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email@example.com manual all digest news 1 month_year 1 1 1 1 1 1 1 50 1 auje3xj 1 1 1 12 25 9 1 article articles summary News date http://cancer.ucsf.edu/news/list/set/10/111 news same past_only https://ti.ucsf.edu/cancer.ucsf.edu/news 9 1 1 1 cancer.ucsf.edu 9 23 UCSF Cancer Center 51 https://ti.ucsf.edu/cancer.ucsf.edu 1 http://cancer.ucsf.edu/sm_template/template.php 2 Cancer Center 2012 5 866 2 2 http://cancer.ucsf.edu manual desc 45 word left US/Eastern http://ti.ucsf.edu/element/auje3xj 9 set News 841 newsfeed http://cancer.ucsf.edu/news http://ti.ucsf.edu/element/auje3xj 25 auje3xj 1 2016-07-23 11:05:45 EDT 2016-07-23 11:05:45 ti.ucsf.edu http://ti.ucsf.edu News list 5939 2015-02-18 11:07:05.110268-06 public UCSF.edu http://www.ucsf.edu/news/2015/02/123266/%E2%80%98most-comprehensive-map%E2%80%99-human-epigenomes-unveiled article 1 3 http://ti.ucsf.edu/element/auje3xj/counter/5939 2015-02-18 10:58:23-06 <p> Two dozen scientific papers published online simultaneously on Feb. 18, 2015 present the first comprehensive maps and analyses of the epigenomes of a wide array of human cell and tissue types. Epigenomes are patterns of chemical annotations to the genome that determine whether, how, and when genes are activated.<br /> <br /> Because epigenomes orchestrate normal development of the body, and disruptions in epigenetic control are known to be involved in a wide range of disorders from cancer to autism to heart disease, the massive trove of data is expected to yield many new insights into human biology in both health and disease.<br /> <br /> The 24 papers describing human epigenomes will appear in print on Feb. 19, 2015 in the journal <em>Nature</em> and in six other journals under the aegis of Nature Publishing Group. Collectively, the papers are a culmination of years of research by hundreds of participants in the Roadmap Epigenomics Program (REP), first proposed in 2006 by academic scientists and key members of the National Institutes of Health. All will be freely available at Nature's <a href="http://www.nature.com/epigenomeroadmap">Epigenome Roadmap</a> website.<br /> <br /> "The DNA sequence of the human genome is identical in all cells of the body, but cell types—such as heart, brain or skin cells—have unique characteristics and are uniquely susceptible to various diseases," said UC San Francisco's <a href="http://cancer.ucsf.edu/people/profiles/costello_joseph.3550">Joseph F. Costello, PhD</a>, director of one of four NIH Roadmap Epigenome Mapping Centers (REMC) that contributed data to the REP. "By guiding how genes are expressed, epigenomes allow cells carrying the same DNA to differentiate into the more than 200 types found in the human body."<br /> <br /> In cancer research, said Costello, the new data will hasten a merging of genomic and epigenomic perspectives that was already underway. "You've had cancer researchers studying the genome—the role of mutations, deletions, and so on—and others studying epigenomes. They've almost been working on parallel tracks, and they didn't talk to each other all that much. Over the past five or six years, there's been a reframing of the discussion, because the most recurrent mutations in cancer affect epigenomic regulators. So the way mutations in the genome play out is through epigenomic mechanisms, and major pharmaceutical companies now view epigenomes as an important target."<br /> <br /> Costello holds the Karen Osney Brownstein Endowed Chair in Neuro-Oncology in the UCSF Department of Neurological Surgery, and is a member of the UCSF Helen Diller Family Comprehensive Cancer Center (HDFCCC).<br /> <br /> The overarching findings of the REP, which include data on 111 distinct human epigenomes from all four REMCs as well as from dozens of individual labs around the world, are covered in a Nature paper for which Manolis Kellis, PhD, of Massachusetts Institute of Technology (MIT) and the Broad Institute of MIT and Harvard, is senior author. In addition to the many implications for normal human biology of "the most comprehensive map of the human epigenomic landscape so far," the authors write, "our data sets will be valuable in the study of human disease, as several companion papers explore in the context of autoimmune disease, Alzheimer's disease, and cancer."<br /> <br /> DNA molecules are long, thin double strands containing genes, the discrete units of information that serve as recipes for the protein-making machinery of the cell. In order for DNA molecules to fit into the small space of the cell nucleus, they are compressed and packed like cooked spaghetti, and also wound around spool-like structures called histones. Chemical epigenetic "marks"—the addition of methyl groups in or near genes, and modifications to histones—determine whether genes are available to be transcribed and translated into proteins. Though epigenetic marks are stable, they are reversible, and they can also be altered by environmental factors such as diet, exposure to toxins, and aging. Such changes affect gene expression, which can lead to disease.<br /> <br /> The REMC directed by UCSF's Costello included researchers from UCSF; the University of California, Santa Cruz (UCSC); the University of Southern California (USC), Washington University in St. Louis (WUSTL); and Canada's Michael Smith Genome Sciences Centre and the University of British Columbia (UBC), in Vancouver, Canada. The group provided important data to the REP on several cell types, including epigenomes of the normal human placenta, sperm, breast cells, blood cells, fetal and adult brain cells, and skin cells. Misha Bilenki, PhD, a member of Costello's REMC with an appointment at Canada's Michael Smith Genome Sciences Centre, is co-first author of the Nature paper of which Kellis, of MIT and Harvard, is senior author.<br /> <br /> A unique contribution of Costello's REMC was the creation, by WUSTL's Ting Wang, PhD, and David Haussler, PhD, and Jim Kent of UCSC, of the <a href="http://epigenomegateway.wustl.edu/browser/roadmap/">Roadmap Epigenome Browser</a>, a web-based tool that gives scientists worldwide open access to the complete data from the REP.<br /> </p> Laura Kurtzman 25 Cell nucleus and chromosomes stained by spectral karyotyping, a technique that allows scientists to visualize all of the human chromosomes by "painting" each pair of chromosomes in a different fluorescent color.<br /> Credit: National Human Genome Research Institute<br /> Cell nucleus and chromosomes stained by spectral karyotyping, a technique that allows scientists to visualize all of the human chromosomes by "painting" each pair of chromosomes in a different fluorescent color. Credit: National Human Genome Research Institute ... 2015-02-18 10:58:08.72499 150218072755large.jpg 300 http://ti.ucsf.edu/files/irMSac/150218072755large.jpg/icon.gif 1048 main 350 http://ti.ucsf.edu/files/irMSac/150218072755large.jpg 486 26743 http://ti.ucsf.edu/files/irMSac/150218072755large.jpg/main.jpg 128 http://ti.ucsf.edu/files/irMSac/150218072755large.jpg/thumb.jpg 128 image 300 1048 http://cancer.ucsf.edu/news/2015/02/18/most-comprehensive-map-of-human-epigenomes-is-unveiled.5939 /ics/2015/02/18/most-comprehensive-map-of-human-epigenomes-is-unveiled.5939/most-comprehensive-map-of-human-epigenomes-is-unveiled.5939.ics 5939 left 1 1 34365 2/18/2015 2015-02-18 08:55:00 8:55 am left 4 1 1 UCSF Researcher Leads One of Four Major U.S. Centers in Global Effort UCSF Researcher Leads One of Four Major U.S. Centers in Global Effort <p> Two dozen scientific papers published online simultaneously on Feb. 18, 2015 present the first comprehensive maps and analyses of the epigenomes of a wide array of human cell and tissue types.</p> Two dozen scientific papers published online simultaneously on Feb. 18, 2015 present the first comprehensive maps and analyses of the epigenomes of a wide array of human cell and tissue types. 4347 1280 Arthur Weiss arthur-weiss 17 1 830 gene sequencing gene-sequencing 17 6 359 Genome genome 17 12 889 Genomics genomics 17 7 1025 Homepage Feature homepage-feature 17 22 927 Joseph Costello joseph-costello 17 3 487 Membership membership 17 35 1281 Michael McManus michael-mcmanus 17 1 479 Neurologic neurologic 17 12 1038 Neurologic Oncology neurologic-oncology 17 8 1282 Susan Fisher susan-fisher 17 1 658 Thea Tlsty thea-tlsty 17 4 2/18/2015 8:55 am US/Eastern 'Most Comprehensive Map' of Human Epigenomes Is Unveiled \'Most Comprehensive Map\' of Human Epigenomes Is Unveiled most-comprehensive-map-of-human-epigenomes-is-unveiled.5939 /2015/02/18/most-comprehensive-map-of-human-epigenomes-is-unveiled.5939 5929 2015-02-11 16:19:13.592194-06 public UCSF.edu http://www.ucsf.edu/news/2015/02/123151/ucsf-medical-centers-parnassus-and-mount-zion-expand-care article 1 4 http://ti.ucsf.edu/element/auje3xj/counter/5929 2015-02-11 16:17:09-06 <p> As UC San Francisco celebrates the successful opening of UCSF Medical Center at Mission Bay, there's excitement also brewing at its other clinical care campuses.<br /> <br /> The successful move of 131 patients to Mission Bay is part of a larger vision for maximizing capacity for growth of other programs at the Parnassus and Mount Zion campuses, where UCSF Medical Center will be expanding services in key areas. <br /> <br /> "The big concept here that we're executing is to really focus and augment our areas of care," said Ken Jones, chief operating officer of the UCSF Medical Center. "Parnassus will remain the expert hub for critically ill adult patients, such as those needing transplants or complicated neurological or musculoskeletal surgery."<br /> <br /> Mount Zion will focus on the needs of ambulatory patients, said Jones. Mission Bay is the third piece of the puzzle, with new facilities for treating complex illnesses in women, children and certain cancer patients.<br /> <br /> The move opens up much-needed space for additional beds at Parnassus – to support growth in surgery and for patients admitted through the busy Emergency Department. The new space also allows for important renovations at Parnassus to update patient rooms, operating rooms and technology.<br /> <br /> "We've already set a new standard with our medical center at Mission Bay, and we're planning to do same thing with renovation and remodeling efforts at Mount Zion and Parnassus," Jones said.</p> <h2> Mount Zion Becomes '23 Hour' Surgery Site</h2> <p> UCSF Medical Center at Mount Zion will continue to operate as a high-end surgery center and to treat women's health and cancer patients. The campus will focus on primary care, including prevention and wellness, expert screening and diagnostic services, and treatment of chronic conditions. <br /> <br /> The medical center at Mount Zion will become a "23-hour stay" ambulatory surgery site, allowing certain patients whose surgeries may involve longer recovery times to be treated as an outpatient, rather than being admitted to the hospital. The center already had several overnight patients in its first week of operation.<br /> <br /> Mount Zion's services for women's gynecological care and the breast cancer center will continue to be areas of focus, along with an emphasis on wellness, quality of life and opportunities for support groups.<br /> <br /> The Helen Diller Family Comprehensive Cancer Center remains at Mount Zion as a critical hub for cancer treatment and research, with four linear accelerator vaults for radiation therapy and an infusion center for chemotherapy.<br /> <br /> Women and cancer patients requiring more serious treatment and overnight hospitalization will be served at the new UCSF Bakar Cancer Hospital and the Betty Irene Moore Women's Hospital at Mission Bay.</p> <h2> Parnassus Focuses on Critical Care</h2> <p> The move of some women and children's services to Mission Bay has freed up critical space at Parnassus to expand its adult emergency department, adding 43 much-needed patient beds. <br /> </p> <p> </p> Kathleen Masterson 25 Just days after UCSF Medical Center moved more than 100 patients to Mission Bay, the Parnassus hospital campus began preparing for major upgrades that will expand key patient care services there. This gurney along with other equipment and medical supplies are being donated to a medical center in Zimbabwe. Photo by Susan Merrell Just days after UCSF ... 2015-02-11 16:16:50.266842 ParnCleanup_0.jpg 354 http://ti.ucsf.edu/files/lC2YDK/ParnCleanup_0.jpg/icon.gif 1041 main 433 http://ti.ucsf.edu/files/lC2YDK/ParnCleanup_0.jpg 770 39691 http://ti.ucsf.edu/files/lC2YDK/ParnCleanup_0.jpg/main.jpg 128 http://ti.ucsf.edu/files/lC2YDK/ParnCleanup_0.jpg/thumb.jpg 128 image 630 1041 http://cancer.ucsf.edu/news/2015/02/10/ucsf-medical-center-at-parnassus-and-mount-zion-to-expand-care.5929 /ics/2015/02/10/ucsf-medical-center-at-parnassus-and-mount-zion-to-expand-care.5929/ucsf-medical-center-at-parnassus-and-mount-zion-to-expand-care.5929.ics 5929 left 1 1 34189 2/10/2015 2015-02-10 14:14:00 2:14 pm left 4 1 1 <p> As UC San Francisco celebrates the successful opening of UCSF Medical Center at Mission Bay, there's excitement also brewing at its other clinical care campuses.</p> As UC San Francisco celebrates the successful opening of UCSF Medical Center at Mission Bay, there's excitement also brewing at its other clinical care campuses. 4337 1133 Bakar Cancer Hospital bakar-cancer-hospital 17 9 954 Carol Frank Buck Breast Cancer Center carol-frank-buck-breast-cancer-center 17 2 234 Mission Bay mission-bay 17 6 937 UCSF Benioff Children's ucsf-benioff-childrens 17 9 2/10/2015 2:14 pm US/Eastern UCSF Medical Center at Parnassus and Mount Zion to Expand Care UCSF Medical Center at Parnassus and Mount Zion to Expand Care ucsf-medical-center-at-parnassus-and-mount-zion-to-expand-care.5929 /2015/02/10/ucsf-medical-center-at-parnassus-and-mount-zion-to-expand-care.5929 5927 2015-02-11 12:04:26.878634-06 public UCSF.edu http://www.ucsf.edu/news/2015/02/123206/president-bill-clinton-tours-new-ucsf-hospitals article 1 4 http://ti.ucsf.edu/element/auje3xj/counter/5927 2015-02-11 12:04:26-06 <p> U.S. President Bill Clinton visited <a href="http://www.ucsf.edu/news/2015/02/122971/ucsf-medical-center-mission-bay-opens-welcomes-131-patients" target="_blank">UCSF Medical Center at Mission Bay</a> on Feb. 5 to view the new state-of the-art facilities for children, women and cancer patients.</p> <p> Invited as a guest of Marc and Lynne Benioff, whose generous contributions made one of the new hospitals – <a href="https://www.ucsfbenioffchildrens.org/" target="_blank">UCSF Benioff Children's Hospital San Francisco</a> – possible, the President visited with children and teens, who shared their experiences since the move to the new site on Feb. 1.</p> <p> Led by a teen patient, President Clinton toured the facilities, including the family-friendly patient rooms, classroom and teen lounge. The teen demonstrated the hospital's unique interactive bedside <a href="http://www.sfchronicle.com/health/article/Robots-and-other-tech-on-display-at-new-UCSF-6049757.php#/0" target="_blank">technology</a>, which enables patients to order room service and movies, Skype coworkers and classmates, update social media and email their clinical team. President Clinton also watched the hospital's fleet of 24-hour <a href="http://www.cnet.com/news/robots-give-a-helping-hand-in-san-franciscos-newest-hospital/" target="_blank">robots in action</a> as they removed and delivered food, linens, medications and lab specimens.</p> <p> They were accompanied by UCSF Chancellor Sam Hawgood, MBBS, and Mark Laret, chief executive officer of UCSF Medical Center and UCSF Benioff Children's Hospitals.</p> <p> </p> 25 2015-02-11 12:03:51.863572 clinton2crop.jpg 421 http://ti.ucsf.edu/files/kwn4Xu/clinton2crop.jpg/icon.gif 1040 main 514 http://ti.ucsf.edu/files/kwn4Xu/clinton2crop.jpg 770 50289 http://ti.ucsf.edu/files/kwn4Xu/clinton2crop.jpg/main.jpg 128 http://ti.ucsf.edu/files/kwn4Xu/clinton2crop.jpg/thumb.jpg 128 image 630 1040 http://cancer.ucsf.edu/news/2015/02/10/president-bill-clinton-tours-new-ucsf-hospitals.5927 /ics/2015/02/10/president-bill-clinton-tours-new-ucsf-hospitals.5927/president-bill-clinton-tours-new-ucsf-hospitals.5927.ics 5927 left 1 1 34158 2/10/2015 2015-02-10 10:02:00 10:02 am left 1 1 1 <p> U.S. President Bill Clinton visited <a href="http://www.ucsf.edu/news/2015/02/122971/ucsf-medical-center-mission-bay-opens-welcomes-131-patients" target="_blank">UCSF Medical Center at Mission Bay</a> on Feb. 5 to view the new state-of the-art facilities for children, women and cancer patients.</p> U.S. President Bill Clinton visited UCSF Medical Center at Mission Bay on Feb. 5 to view the new state-of the-art facilities for children, women and cancer patients. 4335 1133 Bakar Cancer Hospital bakar-cancer-hospital 17 9 1269 Betty Irene Moore Women's Hospital betty-irene-moore-womens-hospital 17 2 234 Mission Bay mission-bay 17 6 937 UCSF Benioff Children's ucsf-benioff-childrens 17 9 2/10/2015 10:02 am US/Eastern President Bill Clinton Tours New UCSF Hospitals President Bill Clinton Tours New UCSF Hospitals president-bill-clinton-tours-new-ucsf-hospitals.5927 /2015/02/10/president-bill-clinton-tours-new-ucsf-hospitals.5927 5921 2015-02-09 12:15:18.191927-06 public UCSF.edu http://www.ucsf.edu/news/2015/02/123111/ucsf-led-study-shows-why-some-targeted-cancer-drugs-lose-effectiveness article 1 4 http://ti.ucsf.edu/element/auje3xj/counter/5921 2015-02-09 12:02:30-06 <p> A protein called YAP, which drives the growth of organs during development and regulates their size in adulthood, plays a key role in the emergence of resistance to targeted cancer therapies, according to a new study led by UC San Francisco researchers.</p> <p> By precisely identifying the mechanism by which elevated levels of YAP promote the survival of cancer cells, the new work points the way to combination therapies that may overcome resistance to individual targeted drugs, the scientists said.</p> <p> Though cancer drugs aimed at specific genetic mutations have had some success in recent years, most patients who have a good initial response eventually develop resistance to these therapies, most likely because cancer cells engage alternative survival mechanisms that lie outside the biological pathways targeted by the drugs.</p> <p> Though oncologists have the option of switching to a different targeted drug after resistance takes hold, many cancer researchers believe that a better strategy would be to forestall cancer cells' eventual escape routes by using customized combinations of targeted drugs at the outset of therapy.</p> <p> "Instead of trying to figure out why patients have developed resistance after it has emerged, we need to decipher what survival tactic tumor cells will be most dependent on when they are challenged with targeted therapy," said the senior author of the study, <a href="http://cancer.ucsf.edu/people/profiles/bivona_trever.3308">Trever Bivona</a>, MD, PhD, UCSF assistant professor of medicine and a member of the <a href="http://cancer.ucsf.edu">UCSF Helen Diller Family Comprehensive Cancer Center</a> (HDFCCC). "We want to learn how to wipe out that alternative survival pathway at the beginning of therapy—to pull the rug out from under those cells right away."</p> <p> In the new research, published in the Feb. 9, 2015 online issue of <em>Nature Genetics</em>, an international team of scientists led by Bivona used a gene-silencing tool called short-hairpin RNAs (shRNAs) to tamp down the activity, one-by-one, of more than 5,000 proteins in lung cancer cells that carried cancer-causing mutations in a gene called <em>BRAF.</em> By simultaneously treating the cells with the cancer drug vemurafenib (Zelboraf), which specifically targets faulty BRAF proteins, the researchers were able to determine whether the drug was more effective when the action of other particular proteins was blocked.</p> <p> These experiments quickly and decisively fingered YAP in vemurafenib resistance, as all six YAP-directed shRNAs employed by the scientists significantly enhanced the drug's effectiveness at killing <em>BRAF</em>-mutant cancer cells. The researchers saw similar results with trametinib (Mekinist), which targets a BRAF-activated protein called MEK. Working with other types of cancer cells carrying <em>BRAF</em> mutations, including cells from human melanoma, colon, and thyroid cancers, the researchers again found that suppressing YAP enhanced the effectiveness of both vemurafenib and trametinib.</p> <p> The collective lab-dish results held up in experiments with animal models in which cells from melanoma and colon cancer were injected under the skin of mice and formed tumors: vemurafenib and trametinib were far more effective in treating these tumors when YAP had been suppressed.</p> <p> The researchers then turned to cells carrying mutations in another important cancer-driving gene, called <em>RAS</em>. Cancers with these mutations are particularly problematic, because the RAS protein is widely considered to be "undruggable"— no effective targeted therapies have been developed for tumors expressing mutant <em>RAS.</em> Like BRAF, the RAS protein also activates MEK, but MEK-targeted therapies have not been particularly effective in patients with <em>RAS</em>-mutant tumors.</p> <p> After YAP suppression, however, the MEK inhibitor trametinib was highly effective when tested in <em>RAS</em>-mutant lung cancer, melanoma, and pancreatic cancer cells, and also against <em>RAS-</em>mutant lung tumors implanted in animals.</p> <p> To ensure that these findings were clinically relevant, the authors examined human tumor samples and found that YAP was highly expressed in <em>BRAF</em>- and <em>RAS</em>-mutant lung cancer and melanoma before patients had received any treatment. Moreover, patients whose tumors had higher YAP levels were more likely to have had an incomplete response when treated with a BRAF and/or MEK inhibitor. Finally, YAP levels rose in tumors when patients developed resistance to those therapies.</p> <p> </p> Pete Farley 25 Trever Bivona, MD Trever Bivona, MD 2015-02-09 12:02:24.017137 bivona.jpg 511 http://ti.ucsf.edu/files/il1hAY/bivona.jpg/icon.gif 1038 main 304 http://ti.ucsf.edu/files/il1hAY/bivona.jpg 375 56991 http://ti.ucsf.edu/files/il1hAY/bivona.jpg/main.jpg 128 http://ti.ucsf.edu/files/il1hAY/bivona.jpg/thumb.jpg 128 image 630 1038 http://cancer.ucsf.edu/news/2015/02/09/ucsf-led-study-shows-why-some-targeted-cancer-drugs-lose-effectiveness.5921 /ics/2015/02/09/ucsf-led-study-shows-why-some-targeted-cancer-drugs-lose-effectiveness.5921/ucsf-led-study-shows-why-some-targeted-cancer-drugs-lose-effectiveness.5921.ics 5921 left 1 1 34132 2/9/2015 2015-02-09 09:59:00 9:59 am left 5 1 1 Work Suggests Combination Therapies Could Overcome Drug Resistance Work Suggests Combination Therapies Could Overcome Drug Resistance <p> A protein called YAP, which drives the growth of organs during development and regulates their size in adulthood, plays a key role in the emergence of resistance to targeted cancer therapies, according to a new study led by UC San Francisco researchers.</p> A protein called YAP, which drives the growth of organs during development and regulates their size in adulthood, plays a key role in the emergence of resistance to targeted cancer therapies, according to a new study led by UC San Francisco researchers. 4329 1276 Alain Algazi alain-algazi 17 1 187 drugs drugs 17 11 555 Eric Collisson eric-collisson 17 3 1025 Homepage Feature homepage-feature 17 22 599 Martin McMahon martin-mcmahon 17 2 487 Membership membership 17 35 903 RAS ras 17 8 1274 therapeutics therapeutics 17 2 410 Trever Bivona trever-bivona 17 7 1275 YAP yap 17 1 2/9/2015 9:59 am US/Eastern UCSF-Led Study Shows Why Some Targeted Cancer Drugs Lose Effectiveness UCSF-Led Study Shows Why Some Targeted Cancer Drugs Lose Effectiveness ucsf-led-study-shows-why-some-targeted-cancer-drugs-lose-effectiveness.5921 /2015/02/09/ucsf-led-study-shows-why-some-targeted-cancer-drugs-lose-effectiveness.5921 5909 2015-02-04 13:53:54.115707-06 public UCSF.edu http://www.ucsf.edu/news/2015/02/123096/apply-intramural-funds-through-ucsfs-resource-allocation-program article 1 5 http://ti.ucsf.edu/element/auje3xj/counter/5909 2015-02-04 13:53:52-06 <div> UCSF's Resource Allocation Program (RAP), which offers a single online application process for a wide variety of intramural grant offerings, is now inviting applications for the Spring 2015 cycle.</div> <div> </div> <ul> <li> The electronic submission deadline is Monday, February 23, at 2 p.m</li> <li> Upgrades to the online application to improve the user experience are in progress, and the form will be available February 17</li> </ul> <div> <strong>New Funding Opportunities</strong></div> <div> </div> <div> The Academic Senate and the Research Evaluation & Allocation Committee (REAC) of the School of Medicine are sponsoring a new grant mechanism called "Independence Support Award" supporting investigators who have not yet succeeded in getting an NIH R01 or similar funding. The purpose of the Independence Support Award is to support investigators who currently have or have completed an NIH career development program award (K series) or another extramural career development grant, and have submitted an NIH R01 (or equivalent) application that was not funded. This award will provide bridge funding to support research costs to address inadequacies of the unsuccessful R01-like proposal and support either on-going or new research.</div> <div> </div> <div> The Helen Diller Family Comprehensive Cancer Center (HDFCCC) is partnering with Kure It Cancer Research to provide a "Grant for Underfunded Cancer Research". Funds are provided by a $100,000 donation from Kure It Cancer Research, and will be matched with $100,000 by the HDFCCC for a single two-year award of $200,000. Kure It Cancer Research was established in 2010 with the goal of being the leader in granting funds to kidney and other cancer researchers conducting innovative research projects to better treat and ultimately cure kidney and other rare cancers.</div> <div> </div> <div> The Post-childbearing award program is now called "New Child Leave Award" and is now available to male investigators and adoptive parents, as well as to childbearing women.</div> <div> </div> <div> RAP has decided to invest in updated technology to both strengthen and ease the submission and review processes. The RAP electronic application form has been completely redesigned and will offer new benefits and ease of use to the applicants. With a simple log in, applicants will be able to create an account and view the status of their submissions through a personal dashboard. The new application will automatically save work in progress and allow for a stepwise submission. The system will alert applicants of missing application components and applicants will be able to independently edit their submissions until the competition is closed. The new system will be implemented in phases, beginning with the development of this new electronic application form, and ending with the launch of a robust online review process. While the user interface will be much improved and have a totally new look and feel, the substantive information required by applicants will be the same as in the past. This will allow for a smooth transition, particularly for investigators who have previously submitted to RAP.</div> <div> </div> Emanuela Volpe 25 2015-02-04 13:52:51.252026 Researchers.jpg 419 http://ti.ucsf.edu/files/cSDNbG/Researchers.jpg/icon.gif 1033 main 246 http://ti.ucsf.edu/files/cSDNbG/Researchers.jpg 370 42313 http://ti.ucsf.edu/files/cSDNbG/Researchers.jpg/main.jpg 128 http://ti.ucsf.edu/files/cSDNbG/Researchers.jpg/thumb.jpg 128 image 630 1033 http://cancer.ucsf.edu/news/2015/02/03/apply-for-intramural-funds-through-ucsfs-resource-allocation-program.5909 /ics/2015/02/03/apply-for-intramural-funds-through-ucsfs-resource-allocation-program.5909/apply-for-intramural-funds-through-ucsfs-resource-allocation-program.5909.ics 5909 left 1 1 33927 2/3/2015 2015-02-03 11:50:00 11:50 am left 1 1 1 <p> UCSF's Resource Allocation Program (RAP), which offers a single online application process for a wide variety of intramural grant offerings, is now inviting applications for the Spring 2015 cycle.</p> UCSF's Resource Allocation Program (RAP), which offers a single online application process for a wide variety of intramural grant offerings, is now inviting applications for the Spring 2015 cycle. 4318 577 funding funding 17 9 17 intranet intranet 17 1 487 Membership membership 17 35 1270 RAP rap 17 1 2/3/2015 11:50 am US/Eastern Apply for Intramural Funds through UCSF's Resource Allocation Program Apply for Intramural Funds through UCSF\'s Resource Allocation Program apply-for-intramural-funds-through-ucsfs-resource-allocation-program.5909 /2015/02/03/apply-for-intramural-funds-through-ucsfs-resource-allocation-program.5909 5866 2015-02-03 14:20:40.772389-06 public UCSF.edu http://www.ucsf.edu/news/2015/02/122971/ucsf-medical-center-mission-bay-opens-welcomes-131-patients article 1 4 http://ti.ucsf.edu/element/auje3xj/counter/5866 2015-02-03 14:20:38-06 <div> With 40 ambulances, approximately 300 UC San Francisco staff and faculty, as well as 100 emergency medical services personnel, UCSF Medical Center on Sunday, Feb. 1, safely transported 131 patients to the new UCSF Medical Center at Mission Bay from its Parnassus and Mount Zion campuses.</div> <div> </div> <div> The move day started at 7 a.m. on the UCSF Parnassus campus; later in the day patients also were transported from the UCSF Mount Zion campus. The last patient to be moved arrived at UCSF Medical Center at Mission Bay at 3:33 p.m. The new medical center also greeted the first baby born at the new hospitals, a healthy boy who entered the world at a little more than seven pounds.</div> <div> </div> <div> The opening of the new hospitals was the culmination of more than 10 years of planning and construction of the complex, which includes UCSF Benioff Children's Hospital San Francisco, UCSF Betty Irene Moore Women's Hospital, UCSF Bakar Cancer Hospital and the UCSF Ron Conway Family Gateway Medical Building.</div> <div> </div> <div> The move day, itself, reflected significant planning. "Patient safety was our top priority during the patient move, along with minimizing disruption to our neighbors. We achieved both goals, thanks to the superb work of our medical center faculty and staff as well as our partners in the City of San Francisco," said Mark R. Laret, CEO of UCSF Medical Center and UCSF Benioff Children's Hospitals. "We have been looking forward to this day for some time, and the opportunity to start providing care in our new location at UCSF Mission Bay."</div> <div> </div> <div> The majority of patients who made the trip on Sunday were children, as UCSF Benioff Children's Hospital San Francisco moved from Parnassus to its new home at UCSF Mission Bay.</div> <div> </div> <div> Strategically located on UCSF's world renowned UCSF Mission Bay biomedical research campus, the new medical center puts UCSF physicians in close proximity to UCSF researchers and nearby biotechnology and pharmaceutical companies in Mission Bay and beyond who are working to understand and treat diseases ranging from cancer to cardiovascular disease to neurological conditions.</div> <div> </div> <div> "Placing the hospitals on our Mission Bay campus underscores our commitment to driving discoveries toward patient care, ensuring that our world-class researchers are working in close proximity to our leading clinical researchers and physicians in the hospitals," said Sam Hawgood, MBBS, chancellor of UCSF. "They also will provide invaluable training for our medical students, the next generation of clinicians who will take care of patients at health care facilities across California and nationally. </div> <div> </div> <div> "Significantly, the move also frees up space on our Parnassus and Mount Zion campuses, which will allow us to enrich our medical programs for adult patients there. With the opening of the hospitals at Mission Bay, we now have integrated clinical care and research programs on all of our campuses, the critical factor that has contributed to UCSF's local, regional and global impact."</div> <div> </div> Karin Rush-Monroe 25 More than 100 people gathered for an all-staff meeting at 5 a.m. to review the day's plan and get revved up for the big move to UCSF Medical Center at Mission Bay. Photo by Noah Berger More than 100 people ... 2015-02-03 14:18:18.883981 MBOpeningCalm.jpg 420 http://ti.ucsf.edu/files/lvho4w/MBOpeningCalm.jpg/icon.gif 1031 main 667 http://ti.ucsf.edu/files/lvho4w/MBOpeningCalm.jpg 1000 64117 http://ti.ucsf.edu/files/lvho4w/MBOpeningCalm.jpg/main.jpg 128 http://ti.ucsf.edu/files/lvho4w/MBOpeningCalm.jpg/thumb.jpg 128 image 630 1031 http://cancer.ucsf.edu/news/2015/02/02/ucsf-medical-center-at-mission-bay-opens-welcomes-131-patients.5866 /ics/2015/02/02/ucsf-medical-center-at-mission-bay-opens-welcomes-131-patients.5866/ucsf-medical-center-at-mission-bay-opens-welcomes-131-patients.5866.ics 5866 left 1 1 33856 2/2/2015 2015-02-02 12:18:00 12:18 pm left 1 1 1 Large-Scale Transport Completed With Support of City of San Francisco Agencies Large-Scale Transport Completed With Support of City of San Francisco Agencies <p> With 40 ambulances, approximately 300 UC San Francisco staff and faculty, as well as 100 emergency medical services personnel, UCSF Medical Center on Sunday, Feb. 1, safely transported 131 patients to the new UCSF Medical Center at Mission Bay from its Parnassus and Mount Zion campuses.</p> With 40 ambulances, approximately 300 UC San Francisco staff and faculty, as well as 100 emergency medical services personnel, UCSF Medical Center on Sunday, Feb. 1, safely transported 131 patients to the new UCSF Medical Center at Mission Bay from its Parnassus and Mount Zion campuses. 4315 1133 Bakar Cancer Hospital bakar-cancer-hospital 17 9 1269 Betty Irene Moore Women's Hospital betty-irene-moore-womens-hospital 17 2 234 Mission Bay mission-bay 17 6 937 UCSF Benioff Children's ucsf-benioff-childrens 17 9 2/2/2015 12:18 pm US/Eastern UCSF Medical Center at Mission Bay Opens, Welcomes 131 Patients UCSF Medical Center at Mission Bay Opens, Welcomes 131 Patients ucsf-medical-center-at-mission-bay-opens-welcomes-131-patients.5866 /2015/02/02/ucsf-medical-center-at-mission-bay-opens-welcomes-131-patients.5866 5860 2015-02-09 12:05:34.902051-06 public UCSFMissionBayHospitals.org http://www.ucsfmissionbayhospitals.org/cancer/ article 1 3 http://ti.ucsf.edu/element/auje3xj/counter/5860 2015-01-31 14:03:44-06 <p> UCSF Bakar Cancer Hospital represents the culmination of the science and expertise that has made our cancer program second to none.</p> <p> This unique new hospital is part of the <a href="http://cancer.ucsf.edu/about"><strong>UCSF Helen Diller Family Comprehensive Cancer Center</strong></a>, the only National Cancer Institute designated comprehensive cancer center in the Bay Area. Located steps away from a world-class research center, the new hospital brings top researchers and clinicians side by side, helping foster new treatments and speeding their delivery to patients.</p> <p> Our state-of-the-art facility provides our oncologists and surgeons – pioneers in nearly every form of cancer – with lasers, robotics, telemedicine systems and other advanced technology of today, with room to accommodate the innovations of the future.</p> 25 2015-01-31 14:06:06.094644 hopstial.jpg 336 http://ti.ucsf.edu/files/h8zNlu/hopstial.jpg/icon.gif 1027 main 324 http://ti.ucsf.edu/files/h8zNlu/hopstial.jpg 608 54269 http://ti.ucsf.edu/files/h8zNlu/hopstial.jpg/main.jpg 128 http://ti.ucsf.edu/files/h8zNlu/hopstial.jpg/thumb.jpg 128 image 630 1027 http://cancer.ucsf.edu/news/2015/01/31/introducing-bakar-cancer-hospital.5860 /ics/2015/01/31/introducing-bakar-cancer-hospital.5860/introducing-bakar-cancer-hospital.5860.ics 5860 left 1 1 34124 1/31/2015 2015-01-31 12:01:00 12:01 pm 2015-01-31 14:03:43.376127 52v7t95COSM 1026 http://youtu.be/52v7t95COSM youtube 1 http://youtu.be/52v7t95COSM video none 400 1 630 52v7t95COSM left 1026 7 1 1 <p> UCSF Bakar Cancer Hospital represents the culmination of the science and expertise that has made our cancer program second to none.</p> UCSF Bakar Cancer Hospital represents the culmination of the science and expertise that has made our cancer program second to none. 4309 1133 Bakar Cancer Hospital bakar-cancer-hospital 17 9 1025 Homepage Feature homepage-feature 17 22 1186 Medical Center medical-center 17 4 1267 Video video 17 2 1/31/2015 12:01 pm US/Eastern Introducing: Bakar Cancer Hospital Introducing: Bakar Cancer Hospital introducing-bakar-cancer-hospital.5860 /2015/01/31/introducing-bakar-cancer-hospital.5860 5840 2015-01-27 14:43:02.235676-06 public UCSF.edu http://www.ucsf.edu/news/2015/01/122886/peter-walter-wins-vilcek-prize-biomedical-sciences article 1 3 http://ti.ucsf.edu/element/auje3xj/counter/5840 2015-01-27 14:42:55-06 <div> Peter Walter, PhD, professor of biochemistry and biophysics, has received the <a href="http://www.vilcek.org/prizes/prize-recipients/2015.html#peter-walter">2015 Vilcek Prize in Biomedical Sciences</a>, which recognizes major contributions to science made by immigrants to America.</div> <div> </div> <div> Walter, professor of biochemistry and biophysics, was born in West Berlin, Germany, during the Cold War era. He joined the UCSF faculty in 1983. A Howard Hughes Medical Institute investigator since 1997, Walter was honored for two main achievements. In the 1980s, while working in the Rockefeller University laboratory of Günter Blobel, PhD, Walter discovered a molecular apparatus in cells called the signal recognition particle, which facilitates the transport of newly minted proteins across a cellular compartment called the endoplasmic reticulum by homing in on address tags on the proteins.</div> <div> </div> Pete Farley 25 Peter Walter, PhD, grew up in Cold War-era West Berlin. He said a childhood in a divided city influenced his interest in science, which "bridges divides and political systems and religions." Peter Walter, PhD, grew up in Cold War-era West Berlin. He said a childhood in a divided city influenced his interest in science, which "bridges divides and political systems and religions." 2015-01-27 14:41:38.265699 peterwalter.jpg 421 http://ti.ucsf.edu/files/fW8j60/peterwalter.jpg/icon.gif 1016 main 514 http://ti.ucsf.edu/files/fW8j60/peterwalter.jpg 770 43161 http://ti.ucsf.edu/files/fW8j60/peterwalter.jpg/main.jpg 128 http://ti.ucsf.edu/files/fW8j60/peterwalter.jpg/thumb.jpg 128 image 630 1016 http://cancer.ucsf.edu/news/2015/01/27/peter-walter-wins-the-vilcek-prize-in-biomedical-sciences.5840 /ics/2015/01/27/peter-walter-wins-the-vilcek-prize-in-biomedical-sciences.5840/peter-walter-wins-the-vilcek-prize-in-biomedical-sciences.5840.ics 5840 left 1 1 33624 1/27/2015 2015-01-27 12:40:00 12:40 pm left 1 1 1 <div> Peter Walter, PhD, professor of biochemistry and biophysics, has received the 2015 Vilcek Prize in Biomedical Sciences, which recognizes major contributions to science made by immigrants to America.</div> <div> </div> Peter Walter, PhD, professor of biochemistry and biophysics, has received the 2015 Vilcek Prize in Biomedical Sciences, which recognizes major contributions to science made by immigrants to America. 4289 462 Award award 17 44 487 Membership membership 17 35 1050 Peter Walter peter-walter 17 5 1/27/2015 12:40 pm US/Eastern Peter Walter Wins the Vilcek Prize in Biomedical Sciences Peter Walter Wins the Vilcek Prize in Biomedical Sciences peter-walter-wins-the-vilcek-prize-in-biomedical-sciences.5840 /2015/01/27/peter-walter-wins-the-vilcek-prize-in-biomedical-sciences.5840 5819 2015-02-18 11:00:46.260766-06 public UCSF.edu http://www.ucsf.edu/news/2015/01/122791/qa-alan-ashworth article 1 4 http://ti.ucsf.edu/element/auje3xj/counter/5819 2015-01-22 16:46:34-06 <div> Alan Ashworth, PhD, FRS, is one of the world's preeminent cancer scientists. This January he assumed the role of the new director of the UCSF Helen Diller Family Comprehensive Cancer Center. Ashworth studies genes involved in cancer risk, and was a key player on the team discovered the gene BRCA2, which is linked to a heightened risk of breast, ovarian and other cancers.</div> <div> </div> <div> He went on to develop a treatment for BRCA1- and BRCA2–related cancers that was recently approved by the FDA. Before coming to UCSF this January, Ashworth was chief executive of The Institute of Cancer Research, London. He answered a few questions about his new position.</div> <div> </div> <div> <em><strong>What brought you to UCSF?</strong></em></div> <div> </div> <div> I saw this as a fantastic opportunity to make a difference. UCSF has always been a place I've enjoyed visiting. I like the scale and breadth of it, the excellence, the feeling of entrepreneurship. The new hospital at Mission Bay was also one of the major drivers in my coming here – it will allow a totally seamless integration between clinical programs and research in a stunning new facility.</div> <div> </div> <div> Additionally, there's a lot of cutting-edge, emerging technologies being developed here in the Bay Area which I'm looking forward to tapping into. I believe partnership between academia and commercial outfits to be critical in developing the next generation of cancer therapies and diagnostic tools.</div> <div> </div> <div> <em><strong>What's your top priority for the UCSF Helen Diller Cancer Center as its new leader?</strong></em></div> <div> </div> <div> We've already started a strategic review of UCSF organizational structures and our strengths and weaknesses.</div> <div> </div> <div> With the opening of the new UCSF Bakar Cancer Hospital at Mission Bay there will be huge new opportunities. This review will allow us to work out how we might be best configured to achieve our ultimate goal, that of delivering new advances to cancer patients in the most rapid fashion.</div> <div> </div> <div> <em><strong>Where do you see the fight against cancer in 10 years? 20?</strong></em></div> <div> </div> <div> History proves that predicting exact timelines in this area is a tricky business.</div> <div> </div> <div> Let's say that in the coming decades we will first see much better and long-term disease control. A smorgasbord of therapies will be available – conventional, new targeted drugs and immune therapies – and these will be increasing used in rational sequential and combination strategies. This will initially result in the stabilization of advanced disease with more cures in early disease.</div> <div> </div> <div> We should also eventually see cures of some currently lethal advanced cancers. Methods of early detection will become much more efficient.</div> <div> </div> <div> Unfortunately, I fear the fight against tobacco use will still be ongoing around the world. Pinpointing cancer risk and cancer prevention of cancer will rightly be getting much more attention.</div> <div> </div> <div> <em><strong>What advice do you have for young researchers?</strong></em></div> <div> </div> <div> I've been asked this question a number of times and generally my answer is "Don't take advice from old f*rts like me." If I have to answer I would say: Find your own path, everyone is different; get excited; take risks, don't be boring; change the world.</div> <div> </div> <div> <strong><em>What are you most excited about regarding living in SF?</em></strong></div> <div> </div> <div> The adventure.</div> <div> </div> 25 Alan Ashworth, PhD, FRS. Photo by Steve Babuljak. Alan Ashworth, PhD, FRS. Photo by Steve Babuljak. 2015-01-22 16:42:08.348129 ashworthcrop.jpg 420 http://ti.ucsf.edu/files/eQsppK/ashworthcrop.jpg/icon.gif 1015 main 513 http://ti.ucsf.edu/files/eQsppK/ashworthcrop.jpg 770 36421 http://ti.ucsf.edu/files/eQsppK/ashworthcrop.jpg/main.jpg 128 http://ti.ucsf.edu/files/eQsppK/ashworthcrop.jpg/thumb.jpg 128 image 630 1015 http://cancer.ucsf.edu/news/2015/01/22/qa-with-alan-ashworth.5819 /ics/2015/01/22/qa-with-alan-ashworth.5819/qa-with-alan-ashworth.5819.ics 5819 left 1 1 34363 1/22/2015 2015-01-22 14:41:00 2:41 pm left 4 1 1 <p> Alan Ashworth, PhD, FRS, is one of the world's preeminent cancer scientists. This January he assumed the role of the new director of the UCSF Helen Diller Family Comprehensive Cancer Center.</p> Alan Ashworth, PhD, FRS, is one of the world's preeminent cancer scientists. This January he assumed the role of the new director of the UCSF Helen Diller Family Comprehensive Cancer Center. 4270 792 About us about-us 17 11 1151 Alan Ashworth alan-ashworth 17 13 1250 director's welcome directors-welcome 17 1 487 Membership membership 17 35 1/22/2015 2:41 pm US/Eastern Q&A with Alan Ashworth Q&A with Alan Ashworth qa-with-alan-ashworth.5819 /2015/01/22/qa-with-alan-ashworth.5819 5791 2015-02-18 10:59:24.184545-06 public UCSF.edu http://www.ucsf.edu/news/2015/01/122661/ucsf-mourns-loss-helen-diller-1929-2015 article 1 4 http://ti.ucsf.edu/element/auje3xj/counter/5791 2015-01-14 15:01:26-06 <p> The UC San Francisco community is deeply saddened to learn of the passing of Helen Diller, who was a longtime champion of UCSF, in particular through her family foundation's support of the UCSF Helen Diller Family Comprehensive Cancer Center. As a philanthropist, advocate, and mentor, Helen will be remembered for her compassion and commitment to improving the world for future generations.</p> <p> Born at Mount Zion Hospital and raised in San Francisco, Helen was the only daughter of Dora and William Samuels. She watched her father work his way up from clothing salesman to shop owner, and she credited her parents with instilling in her the importance of giving back.</p> <p> "It's never too late, too early, or too often to give back and make the world a better place," she said.</p> <p> She met her husband, Sanford, at UC Berkeley when they were both undergraduates. Married for more than six decades, the couple raised three children: sons Brad Diller and Ron Diller, and daughter Jackie Safier, a member of the UCSF Foundation Board of Directors.</p> <p> In her role as president of the Helen Diller Family Foundation, Helen worked diligently at providing for the causes she believed in and won several awards for her unwavering efforts. She served as the Northwest president of the American Friends of Hebrew University and as chair of the Bay Area Friends of the Weizmann Institute of Science. She received the Scopus Award from Hebrew University, the Visionary Leader Award from the San Francisco-based Jewish Community Federation, and the Lifetime Achievement Award from the National Society of Fundraising Professionals, among numerous others.</p> <p> Helen's generosity touched many lives, especially those of young people through her support of programs such as the Diller Teen Fellows leadership program and the Diller Teen Volunteer Service Awards. She valued the power of education, as evidenced by the Helen Diller Family Foundation's support of Jewish Studies at UC Berkeley and UC Santa Cruz along with many other projects and programs both in the United States and around the world.</p> <p> In recent years, championing groundbreaking research rose to the top of Helen's "to do" list. In June 2009, UCSF inaugurated the Helen Diller Family Cancer Research Building at Mission Bay, specializing in leading-edge research to detect, treat, and prevent cancer.</p> <p> "Helen was a visionary and a tireless philanthropist," said Sam Hawgood, MBBS, chancellor of UCSF. "It is a fitting tribute to her memory that so many people will associate her name with health, hope, and happiness."</p> <p> Helen's legacy to make a difference in the world of cancer research will be realized in the decades ahead in the talented UCSF scientists, researchers, and physicians who will work together in the Helen Diller Family Cancer Research Building to improve treatments for cancer patients and find a cure. In this way, her true spirit will live on as will her desire to make the world a better place.</p> <p> In her words, "I wanted to do something for cancer and to do something that would be the finest in the world when it came to research."</p> <p> </p> 25 Photo courtesy the Diller family. Photo courtesy the Diller ... 2015-01-14 15:00:04.279044 Helen Diller 2.jpg 630 http://ti.ucsf.edu/files/i0IvTi/Helen Diller 2.jpg/icon.gif 1008 main 856 http://ti.ucsf.edu/files/i0IvTi/Helen Diller 2.jpg 825 198811 http://ti.ucsf.edu/files/i0IvTi/Helen Diller 2.jpg/main.jpg 128 http://ti.ucsf.edu/files/i0IvTi/Helen Diller 2.jpg/thumb.jpg 128 image 607 1008 http://cancer.ucsf.edu/news/2015/01/14/ucsf-mourns-loss-of-helen-diller-1929-2015.5791 /ics/2015/01/14/ucsf-mourns-loss-of-helen-diller-1929-2015.5791/ucsf-mourns-loss-of-helen-diller-1929-2015.5791.ics 5791 left 1 1 34362 1/14/2015 2015-01-14 12:58:00 12:58 pm left 6 1 1 <p> The UC San Francisco community is deeply saddened to learn of the passing of Helen Diller, who was a longtime champion of UCSF, in particular through her family foundation's support of the UCSF Helen Diller Family Comprehensive Cancer Center.</p> The UC San Francisco community is deeply saddened to learn of the passing of Helen Diller, who was a longtime champion of UCSF, in particular through her family foundation's support of the UCSF Helen Diller Family Comprehensive Cancer Center. 4245 763 about about 17 8 792 About us about-us 17 11 1248 Helen Diller helen-diller 17 2 1246 Support Us support-us 17 2 1/14/2015 12:58 pm US/Eastern UCSF Mourns Loss of Helen Diller (1929-2015) UCSF Mourns Loss of Helen Diller (1929-2015) ucsf-mourns-loss-of-helen-diller-1929-2015.5791 /2015/01/14/ucsf-mourns-loss-of-helen-diller-1929-2015.5791


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Friday, November 16, 2012
iMachining CNC Demo by SolidCAM: December 5, 2012
Witness iMachining, a revolution in CNC machining, as it carves through the hardest materials with the smallest tools. With an optimal tool path and a Technology Wizard for automatic calculation of cutting conditions, iMachining will save up to 70% of your machining time while dramatically increasing your tool life.
See the SolidCAM team cut a steel part LIVE from the comfort of your chair. Wednesday December 5th at 10:30AM and repeated at 1:00PM (Eastern).
Posted by Natalia Kostylev at 9:36 AM
Labels: cnc machining, imachining, solidcam
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