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, Volume 23, Issue 5, pp 379-409
First online:
The Role of Atmospheric Aerosols in the Origin Of Life
- Adrian TuckAffiliated withNOAA Aeronomy Laboratory
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Recent results from the real time analysis of individual aerosol particles by laser mass spectrometry have revived interest in the inverted micelle structure for aerosols containing organic molecules; indeed for many aerosols the organic content is high enough, for example ∼50% by mass in the tropical upper troposphere, that it is likely to be the only viable structure. It is pointed out that atmospheric aerosols would have had many advantages as prebiotic chemical reactors, having the potential to address several key problems in a way arising naturally from the probable geophysical and chemical environment on the prebiotic planet. Bacterial and viral size can be predicted for these structures by an equation combining atmospheric aerodynamics and gravity, and which is therefore applicable to other astronomical objects which are candidates for supporting life. Experimental tests and mathematical modelling of the early stages of the chemical evolution of aerosols should be possible.
Reference tools
- Title
- The Role of Atmospheric Aerosols in the Origin Of Life
- Journal
Surveys in Geophysics
Volume 23, Issue 5 , pp 379-409
- Cover Date
- 2002-09
- Print ISSN
- 0169-3298
- Online ISSN
- 1573-0956
- Publisher
- Kluwer Academic Publishers
- Additional Links
- Topics
- Keywords
- aerosols
- amphiphiles
- membranes
- origin of life
- prebiotic atmosphere
- Industry Sectors
- Authors
- Adrian Tuck (1)
- Author Affiliations
- 1. NOAA Aeronomy Laboratory, 325 Broadway, Boulder, CO, 80305-3328, USA


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SDCC: "Batman: The Killing Joke" Cast & Crew Debuts Film at Comic-Con International
Every day this month I'm going to feature a current comic book writing "star," someone who I think is a very good writer.
I'm mostly going to try to keep from the biggest names as much as possible, because, really, do I need to talk more about the awesomeness of Alan Moore, Neil Gaiman and Warren Ellis?
Here is the archive of previously featured writers.
Today we look at a hilarious comic book comedy duo.
Andrew Boyd and Ryan Yount are the co-writers of the hilarious Scurvy Dogs comic book series (Yount draws the book), which is collected into one delightfully packed with content volume by AIT/Planet-LAR.
The series stars a group of odd pirates who are tying to make it in modern society where they are quite the anachronism. The group is made up of Captain Blackbeard, McDougal the strongman, Jefe the crazy Spaniard, Pappy, the old guy with the eyepatch, hook hand, and peg leg and Irish Pete, the mute scrapper.
To say that these stories are madcap would be to undersell the term "madcap," as these comics are just off the wall laugh riots.
Bill Reed featured the book as one of his Reasons to Love Comics here, and he helpfully shares a few pages from the comic to show you some of the absolutely zany jokes this comic tells (Bill also supplied the description of the cast used above).
How about when the comic turns just to crayon drawings out of nowhere?
This scene with the Portuguese lepers is the opener of the book and leads to one of the best punchlines I've seen – it is the sort of thing you just give to people to read and that will sell the book right there.
I only wish that Boyd and Yount would give us more Scurvy Dogs!
Someone has GOT to get me a copy of their one-shot follow-up to Scurvy Dogs (both Boyd and Yount have full-time jobs, so they don't get to do too much comic output)….American Space Ninja (in Space)!
But I will settle for the pair doing more work together in the future!
I have the Scurvy Dogs miniseries. It was a crazy book. I will have to dig them out and reread the series. I was sorry to see it go.
I picked the trade up a while back and was disappointed. It was funny at first, but got old rather quickly. It's still sitting on my nightstand about half way read. I'll probably get back to it at some point. Maybe it works better in monthly doses.
Ahh, that bit where Pappy breaks the microwave still makes me laugh out loud. I love this series.
I had no idea they teamed for another book after Scurvy Dogs. I've gotta track that down, too.
Hi, Brian. I met Andrew and Ryan at the Staple! Expo in Austin, TX a couple of years ago. I picked up a copy of American Space Ninja (in Space). It's just a little ashcan sized comic. If you'll send me an e-mail, I'll make a scan of it for you. They published a short story called Team Building Exercise (or something similar – I don't have it in front of me, and I can't quite remember) that's pretty funny as well.
Good call highlighting Scurvy Dogs. Hands down the funniest book that I've ever read. In a perfect world these two creators would be millionaires and I'd be on the Scurvy Dogs ride at Disney, drunk, right now.
I keep on loaning this trade out and hoping it gets returned, as I would be tempted to abscond with such comedy gold (gold, Jerry!). It's probably the best "funny" comic I have, and I get those Penny Arcade trades (sorry, guys) AND still have a few Chuck Austen X-titles (funny in a different way).
Comics Should Be Good accepts review copies. Anything sent to us will (for better or for worse) end up reviewed on the blog. See where to send the review copies.

subset: commoncrawl


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Branded Content
Introducing BASF's new Experiential Skin Care – BASF Introduces Experiential Skin Care
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The right to play: New Rhode Island law requires recess in elementary schools
Where's Waldo? Construction worker cheers up sick kids with sweet game
Prince Harry reveals he regrets not speaking about Princess Diana's death
Savannah Guthrie to interview President Obama amid DNC
How necessary is it to build a wall across the Mexican border?
Former gang rivals providing affordable meals with 'Trap Kitchen'
Donald Trump goes in for an 'air kiss': See this week's highs and lows
What do leaked DNC emails mean for Clinton, Trump?
University of Florida football player stops rape of unconscious woman
Donald Trump: Immigrants from France, Germany could face 'extreme vetting'
Democrats reach compromise to limit the role of superdelegates
Burned body found as wildfires threaten 1,500 California homes
See how this little girl's response to a crying homeless man is inspiring others
Homeless student biked 6 hours and slept in a tent just to register for college
Happy 3rd birthday, George! Little prince celebrates with adorable new photos
Stranger answers 'Hail Mary' plea after couple loses wedding ring
After debilitating dog bite, man starts charity for abused animals
Anne Hathaway posts moving tribute to 'Princess Diaries' director Garry Marshall
Ivanka Trump admits she's 'terrified' to introduce her father at the RNC
Eric Trump to Ted Cruz: Don't come on stage if you won't endorse my dad
Trump campaign chief Paul Manafort: Ted Cruz 'made a mistake' at RNC
How one children's hospital is using Pokemon Go to brighten smiles
The simple way this employee helped a mom of twins is winning hearts everywhere
California couple finally claims their share of the $1.6 billion Powerball jackpot
Powerful photo shows children of police officer praying he comes home safely
Strangers surprise man who walks 16 miles to 2 jobs with a new car
Chris Christie: 93 percent of Melania's speech differed from Michelle's
See the cool surprise a thoughtful boy left his mailman during a heatwave
Singer who is blind wows RNC with powerful performance of national anthem
Duchess Kate's sister Pippa Middleton is engaged!
Melania Trump on convention speech: 'I wrote it with as little help as possible'
Family of crash victim says ghostly image is 'likely' his way of saying goodbye
Boston bombing survivor finishes race while pushing his hero's wheelchair
See how this man warmed the hearts of many — with only an umbrella
Pure gold! Watch Team USA jam to Justin Timberlake's 'Can't Stop the Feeling'
The best optical illusions of 2016 will give your brain a workout
Daughters of slain Dallas police officers share touching moment at memorial
'I crossed over': Survivors of near-death experiences share 'afterlife' stories
Somber cartoon tributes pour in across social media following Nice attack
Dorothy Hamill looks back on Olympic gold, her famous haircut and fight with cancer
Meet Houdini and Grace, 'miracle' kittens rescued from Walmart refrigerator
News Video


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For the Record
Published: Saturday, August 29, 2009 at 4:30 a.m.
Last Modified: Friday, August 28, 2009 at 5:16 p.m.
Mission Hospitals
u A son, born on Tuesday, July 14, 2009 to Stacy Reid and Uriah Clouse of Hendersonville.
Emergency Notes Henderson County fire calls
The Henderson County Fire Commission reported the following alarms between noon Thursday and noon Friday:
u Bat Cave, emergency, 6:11 a.m.
u Blue Ridge, emergency, 2:58 p.m.; emergency, 6:06 p.m.;
u Mountain Home, emergency, 7:03 p.m.; heart attack, 7:28 p.m.; emergency, 7:03 p.m.; heart attack, 7:28 p.m.
u Valley Hill, emergency, 3:23 p.m.
Hendersonville fire calls
The Hendersonville Fire Department responded to the following calls from noon Thursday to noon Friday:
u Emergency, 2:38 p.m.
u Heart attack, 5:10 p.m.
u Victim down, 8:32 p.m.
u Victim down, 9:12 p.m.
Henderson County EMS
The Henderson County Emergency Medical Service reported the following calls between noon. Thursday and noon Friday:
u Four routine transports.
u 18 medical emergencies, 15 people transported.
u Two motor vehicle accidents, two people transported.
u Four out of county, to Mission Hospital in Asheville.
u Three calls ambulance not needed.
Henderson County Rescue Squad
The Henderson County Rescue Squad responded to the following calls Thursday.
u Death investigation, 4:51 p.m.
u Emergency, 9:27 a.m.
Crime Report Henderson County Sheriff
The Henderson County Sheriff's Department responded to 344 calls Thursday. Deputies served four warrants.
Hendersonville Police
The Hendersonville Police Department reported 93 calls Thursday. Officers made one arrest, investigated three accidents and provided two assists to other agencies.
The following crimes and incidents were reported Thursday, according to law enforcement records:
Henderson County Sheriff's Department
u Larceny, Industrial Park Road, 8:43 a.m.
u Larceny, Bear Creek Lane, 12:44 p.m.
u Vandalism, Orchard Road, 5 p.m.
u Fraud, New Airport Road, 9:07 p.m.
Hendersonville Police Department
u Fraud, Highway 64 East, 9:02 a.m.
u Larceny, Howard Gap Road, 10:07 a.m.
u Larceny, Highway 25 North, 10:09 a.m.
u Assault, Hillview Boulevard, 12:24 p.m.
Fletcher Police Department
u Discharging a firearm, Cane Creek Industrial Park, 3:43 a.m.
u Fraud, New Airport Road, 8:38 p.m.
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Brief history-
I'm pregnant with baby #3, 28 years old, preeclampsia history in the past, extensive blood clot in left leg...
We've been seeing my family doctor so far, we're 15w5d, and soon we'll have to go to my OB. My OB is super great, definitely intelligent, and nice, but she's always sooo busy. I'm considering changing doctors because she's so difficult to get in to see. I'm not confident that she would have the time to deliver our baby.
Then secondly, we are about 35 minutes NE of Grand Rapids, but we're in Muskegon often (my husbands family is there), so I'm not sure if we should still seek a doctor in the GR area or if there are any doctors or a team of doctors that are in GR and Muskegon?
Do you recommend any doctors?
(I had a midwife with my first pregnancy and was less than impressed. The doctor who delivered my son has since retired and his daughter in law took over his practice and is my current OB.)


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I have setup my Notebook to dual boot for CentOS 6.3 (64-bit) and Ubuntu 12.04 (32-bit) and both have been configured for ntp (network time protocol) with proper time zones (India).
But they are showing an exact time difference of 5 1/2 hours. Only one of them is showing the proper time. Why is it so? I made sure both OS are configure to ntp and the time zones are set proper.


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updated 04/12/2010 AT 9:00 AM ET
•originally published 04/12/2010 AT 10:00 AM ET
Count Hugh Hefner as one of many who were surprised by Jenny McCarthy and Jim Carrey's recent split.
"I don't think any of us saw it coming. From the outside looking in, it looked like a magic couple," the Playboy founder told PEOPLE at his 84th birthday celebration at Las Vegas's Palms Casino Resort on Saturday.
He added: "I thought she found the right one."
Hefner has not spoken to McCarthy, 37, a former Playboy centerfold and 1994's Playmate of the Year, since the split, but is confident she will be fine, saying, "She's a strong person."
As for his own love life, Hefner says he's as happy as he's ever been with girlfriend Crystal Harris, 23. "It's as good a relationship as I've had in my life," he says. "It's wonderful. She's a real feet-on-the-ground lady and very sincere, and I love her."
Will we be hearing wedding bells anytime soon? "I love her enough to marry her, but we'll see," Hefner says. "I don't want to spoil the relationship, because it's very special."


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Sandra Bullock and Ryan Reynolds's visit to Wyoming last weekend also included a low-key dinner with friends.
The Proposal costars – who a source has told PEOPLE are "like brother and sister" – made their way to Rendezvous Bistro in Jackson Hole on Sunday.
Sans Bullock's baby son Louis, who accompanied the actress, 47, and Reynolds, 34, on the trip, the duo joined two other guests for what a source says appeared to be a "really informal" meal.
"They didn't seem like they were a couple," the source says. "It was very relaxed, totally friendly. She wasn't romantic with anyone at the table."


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For a few brief, shining moments, it looked like another "splendid little war," to borrow Secretary of State John Hay's description of the U.S. triumph over Spain in 1898. Just six weeks after American and allied coalition forces had begun "Operation Iraqi Freedom," President George W. Bush landed on the deck of the USS Abraham Lincoln to announce the end of major combat operations. Above and behind the President, a banner announced triumphantly, "Mission Accomplished."
A few days prior to the assault on Libya by coalition forces, Secretary of Defense Robert Gates strongly cautioned against imposing a "no fly zone" on that troubled nation because doing so would constitute going to war against Libya. He said a "no fly zone" he would mean attacking airfields, fuel dumps, and whatever else might be needed to keep Moammar Gadhafi from using his air force. And this, he asserted, adds up to war.
A "sense of the Senate" resolution by Senator Rand Paul (R-Ky., left) opposing President Obama's Libyan intervention using Obama's own words as a Senator has tied up the U.S. Senate as Democratic Party leaders avoid an embarrassing vote against the leader of their party. Paul's resolution had been offered as an amendment to the Small Business Reauthorization bill.
The U.S. government is in the process of developing a Smart phone application that effectively wipes a mobile phone clean of any information pertaining to the owner's revolutionary "democratic movement" that may be discovered by government or military officials, and sends a single last-minute text message to the rest of the revolutionaries warning them of the capture of the cell phone's owner, as well as that person's location.
The Bush-Obama-Neocon DoctrineWritten by Michael Tennant
It's official: When it comes to foreign policy, Barack Obama's first term is really George W. Bush's third.


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Having stayed here before, it was a no brainer. This is one of the nicest Holiday Inn express properties you'll find anywhere. Very clean, decent location and priced modestly.
Room A/C worked very well. Could have hung slabs of meat in there if you wanted.
Breakfast is typical Holiday Inn fare which isn't bad just typical.
- Official Description (provided by the hotel):
- The Holiday Inn Express Hotel Lynchburg is located in the heart of Central Virginia s exciting attractions, business and colleges. The hotel surrounds our guests with the conveniences that make business and leisure easy. We are located within minutes to major business such as Framatone, Areva, Frito Lay and Georgia Pacific. Any business traveler would agree with the Lynchburg Regional Airport only five miles from the hotel that you couldn t get closer. We are also minutes away from several outstanding colleges including Liberty University, Lynchburg College, Sweet Briar College and Randolph-Macon College. With the many scenic and historic attractions so close to Lynchburg, our hotel is a perfect choice. The Blue Ridge Mountains provide a perfect backdrop for a drive to visit the National D-Day Memorial, Appomattox Court House and Thomas Jefferson s Poplar Forest. The Holiday Inn Express Lynchburg proudly features a friendly staff and comfortable guest rooms with a spacious work desk with free wired high-speed Internet access. Guests can jump start their morning with our free deluxe continental breakfast. Take a relaxing dip in our seasonal outdoor swimming pool, or work out at our nearby off-site fitness center with complimentary passes available as the front desk. Come let us show you why it is 'SMART' to stay with us at the Holiday Inn Express Lynchburg, Virginia. ... more less
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- TripAdvisor is proud to partner with Booking.com, IHG, Expedia, Hotwire, Priceline, Hotels.com, Odigeo and Travelocity so you can book your Holiday Inn Express Lynchburg reservations with confidence. We help millions of travelers each month to find the perfect hotel for both vacation and business trips, always with the best discounts and special offers.
- Also Known As:
- Holiday Inn Express Lynchburg Hotel Lynchburg


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By Bertram de Souza (Contact)
Published April 8, 2008
In detailing the sexual harassment allegations made by two female employees of the Ohio Attorney General's Office against Anthony Gutierrez of Liberty, a political appointee of Attorney General Marc Dann's earning $87,000 a year, The Columbus Dispatch shed light on a unique way Dann conducts official business.
Based on the written complaint filed by one of the women, Cindy Stankoski, 26, The Dispatch reported that less than three weeks after she was hired, Gutierrez, a neighbor of Dann's in Liberty, pressed her to have a drink with him after work. The newspaper reported that Gutierrez took Stankoski to two downtown bars and to a steakhouse. While there, Gutierrez received a call from Dann urging both of them to come to the condo he was sharing at the time with Gutierrez and Leo Jennings III, the AG's communications chief.
The newspaper reported that when they got to the condo, Dann's scheduler, Jessica Utovich, was there. According to Stankoski's complaint, Utovich "walked in w. pj's and laptop" and lay down on the floor to work on her computer.
Here's how Jennings, another Valley resident, explained Utovich's presence in the condo: He told the newspaper that staffers, including Utovich, occasionally visited the condo, but only for work-related purposes: "She was there to deliver schedules."
Thus the question: Were the pajamas she was wearing from Victoria's Secret? If they were, it would explain a lot, given that the world-famous lingerie chain has a line of lounge wear, such as pajamas, that are popular with women who take their work home.
The other question that Utovich's presence in the condo triggers is this: Was Dann dressed in a smoking jacket (a la Hef —Hugh Hefner)?
Why is it that so many of our "community leaders" don't understand that professionalism does not include asking young women working for them to have sex? Within the past few months we had to listen to the sordid accusations involving Joe McRae's behavior and now we get to hear how the state's work is being done at the AG's office.
Since when does professional behavior include doing business at a bachelor pad? Do these people not have access to email or fax machines? Why is it necessary for a young female scheduler to hand deliver a document to the AG after hours. Hand-delivering papers to a boss at his bachelor pad is a lot different than delivering them to the family home with the wife, kids, and family dog present.
Shame on Marc Dann for allowing his office staff to act in such an unprofessional manner. I voted for him and was happy to have someone from this area in that office. Again, the Mahoning Valley is disappointed by one of our own who was given the opportunity to accomplish great things for us and blew it.
Dann better clean up his AG's office because he'll have an Attorney embarrassing his office here very soon.
Put up or shut up Marc Dann. If you won't put up, expect to lose your job in the coming years!
True Valleyred, I feel their is more than is comming out right now. I am guessing here, But I bet something comes out involving Dann. It would be sad, those are my feelings, Hope they are wrong. Also, Look at the people he has given jobs to.


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Celiac Disease Health Center
News Related to Celiac Disease
Celiac Disease: Faster Gluten Test
Nov. 14, 2008 -- Scientists have developed a new test that could speed up identification of gluten, a trigger for people with celiac disease. Gluten-free foods are already on the market. But gluten can lurk in products that people might not expect. People with celiac disease have to avoid gluten comRead Full Article
Celiac Disease Underdiagnosed?
May 20, 2008 -- Most Americans who have celiac disease probably don't know it. A new study shows that the criteria used to diagnose the disorder may be too stringent, leaving many people undiagnosed and untreated. It is estimated that one in every 100 Americans may be affected by celiac disease. ButRead Full Article
New Celiac Disease Clues
March 3, 2008 -- New information about a possible genetic cause of celiac disease could soon lead to better treatments for the immune disorder. Researchers have identified a group of seven gene regions that appear to predispose people to celiac disease. People with celiac disease cannot tolerate gluRead Full Article
Celiac Disease Clue Found
June 11, 2007 -- Gene studies link celiac disease to a defective immune signal. Celiac disease is a digestive disease sometimes called celiac sprue or gluten-sensitive enteropathy. When a person with celiac disease eats wheat or other foods containing gluten, damage to the small intestine results. IRead Full Article
Celiac Disease Linked to Dementia
Oct. 13, 2006 -- Adults who develop the digestive condition known as celiac disease appear to be at increased risk for dementia, according to new research from the Mayo Clinic. Celiac disease is a disorder caused by an immune reaction to eating gluten, found in some grains such as wheat, barely, andRead Full Article
Cereal for Infants: A Link to Celiac Disease?
May 17, 2005 -- Infants who are introduced to cereals between the ages of 4 months and 6 months may have a lower risk of developing celiac disease than those who start eating cereal earlier or later, according to new research. Celiac disease is a condition in which the small intestine becomes inflamRead Full Article
Celiac Disease Testing May Help Osteoporosis
Feb. 28, 2005 - Screening people with osteoporosis for a condition that makes it difficult to digest wheat may help improve treatment and reduce the risks associated with the common bone-weakening disease. A new study shows that celiac disease, a disorder of the immune system that damages the smallRead Full Article
Hold the Oats for Celiac Disease?
Oct. 18, 2004 -- The on-again, off-again relationship between people with celiac disease and oats may be off again. For years, people with the chronic immune system disorder were told to avoid oats as well as wheat, rye, and barley. The reason for the food ban: gluten, a form of protein found in somRead Full Article


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2007 Mazda 3 Hatchback s Grand Touring 4dr Hatchback (2.3L 4cyl 5M)
Purchased this car 6 years ago, car has 50,700 miles on it.
Overall it gets me from point A to point B, however I have had to replace brake cable, calipers, rotors and brakes as well as the rear and front supsension.
Apparently this is a not uncommon issue with the vehichle.
Car warranty should be better as well only 3 years 36K miles
Good sound system, manual transmission, heated seats for cold winter days
Better warranty offer, use better rotors/brake pads.
2007 Mazda 3 Hatchback s Grand Touring 4dr Hatchback (2.3L 4cyl 5M)
It's been a great car and the list of features is fantastic for the money. I put some Continental Tires ($800) on it which have improved the wet handling tremendously - anxious to try it in the snow. I was afraid of it in those conditions with the original tires. The ride quality on the Continentals is much better than the original tires. My paint has way too many chips like others. I'm satisfied with 27 mpg avg for this level of power. Manual is very smooth. Pedals are a little close together though and I have a size 10 shoe. Needs heated mirrors. I think I will have to get a BMW 3 series next to find something I would consider an upgrade in handling and luxury.
Heated seats, Xenon lights, climate control, I like the look of the 17" wheels, silky transmission, sporty handling.
Heated mirrors, better paint, more pedal room, 30 more HP, and send it from the factory with a decent set of tires. I'd like to see it offered with about 50 more HP and AWD - that would be a fun car and I think Mazda might do that better than Subaru and cheaper than Audi.
2007 Mazda 3 Hatchback s Grand Touring 4dr Hatchback (2.3L 4cyl 5M)
For the money, you won't find a better driving hatchback out there (minus the Mazdaspeed3, GTI, STI, etc. of course). Typical Mazda steering, powerful brakes, and fantastic grip. If the aforementioned are more important to you than mpg, the Maz3 is definitely worth a look. Fuel economy is ok, but certainly not great for a compact, as has been said by many others. Driving from CA to NY (all interstate with speeds around 75-80), I averaged around 30 mpg. A typical tank with mixed city and hwy driving will yield 22-26 mpg. For those who cannot see their gauges in daylight, you need to push that little button on the instrument cluster to alternate your dash lighting - there are two modes
Steering, handling, brakes. Versatile interior layout (was able to transport a full-sized clothes dryer with some room to spare), classy interior design. For the money, you won't get a better feature set on a car.
Snowflake wheels are awful. The Bose system really should have mp3 capability (2008 and later models do), interior plastics are hard and scuff easily.
2007 Mazda 3 Hatchback s Grand Touring 4dr Hatchback (2.3L 4cyl 5M)
This is a great car and I highly recommend it to anyone that asks. However, I would like to see a rack option other than buying aftermarket model. All in all, this is a great car and I look forward to the 1.5 hours I spend on the road going to and from work every day.
I like them all.
I would recommend that there be battery power until the doors are open. In my old car I could turn the car off & take the keys out and the radio, windows & sunroof would all work for 10 minutes or until i opened the door. Also, work on iPod integration.
2007 Mazda 3 Hatchback s Grand Touring 4dr Hatchback (2.3L 4cyl 5M)
I chose the Mazda3 over a Civic EX coupe because I was looking for performance, styling and versatility over mileage. After 2,000 miles, I'm finding all of that and more. This car is a pleasure to drive on long trips and short. Handling is superb and mileage has been excellent, generally getting 29-33 mpg. This car offers Honda quality with twice the styling.
Stability and traction control, leather seats, Bose system, smooth manual transmission, and many more.
Delay feature allowing lights and sunroof closure after turning off engine, standard homelink, choice of interior color. Other than that I'm not sure there is anything left at this price point.
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Proposition 1, which would create a Seattle Park District and raise an estimated $48 million a year to support city parks, is narrowly passing with support from 52 percent of the people.
The measure would increase home property taxes by 33 cents for every $1,000 of assessed value. For a home worth $300,000, taxes would increase by about $100 a year.
It would replace an expiring six-year parks levy that raised $146 million this year and is about to expire.
Supporters of proposition, including Mayor Ed Murray, say it is needed it is needed as a permanent fix to address a $270 million maintenance backlog and restore community center hours.
Opponents of the measure say they love parks, but don't want voters to write city council members a blank check. They fear this could lead to wasteful spending. Opponents also say that once voters give up the right to vote on parks every six years, they lose their voice.
About two-thirds of the votes have been counted so far.


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Shelter Bay Marina at night. Photo copyright Jen Edney 2009
Screen shot of Intrepid passing through the Miraflores Locks
Walking through the jungle with Jen and friend
Passing through the Gatun Locks at night
Prepping my new fenders - Panama Canal-style!
Cooking breakfast for the linehandlers
Intrepid tied to Pura Vida
Interesting view of the canal from land - Photo by Laurence Sunderland
Zac arriving at Shelter Bay in the rain - Photo by Laurence Sunderland
Fenders a la Panama - Photo by Laurence Sunderland
Meeting with the admeasurer - Photo by Laurence Sunderland
Interviewing in Panama City Photo courtesy of Panama Tourism Authority
A feast for hungry travelers - Photo courtesy Panama Tourism Authority
At the sail maker - Photo by Zac Sunderland
View from the Country Inn - Photo by Laurence Sunderland
Under the Bridge of the Americas back into the Pacific


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Applied Materials comes to XiAn
Clean energy R&D finds a home in China
CAP has sent a cohort of their experts into the field to China to study the rapidly expanding Chinese efforts to support clean energy R&D, innovation, manufacturing, and deployment. At one of their first stops on the tour, Julian Wong and Sarah Miller document how and why Serious Materials, a titan of Silicon Valley Innovation, has chosen to locate its new solar energy R&D facility in Xi'An province, instead of California.
Applied Materials, a prominent Silicon Valley technology firm that has been the leading maker of equipment to the semiconductor chip industry since the early 1990s, captured industry headlines when it announced the opening of the world's largest nongovernmental solar research and development center in China and relocated its chief technology officer, Mark Pinto, from California to Beijing. And then The New York Times published a prominent profile of the new R&D center just last month.
So we hopped a two-hour flight from Beijing on Friday to visit Applied Materials' new facility, which consists of a center for research and development, engineering, product demonstration, testing, and training for thin film and crystalline solar module manufacturing equipment and processes. It's located not in Beijing or Shanghai, but in Xi'An, home to the famous Terra Cotta Warriors and about 8 million people""a midsize city by Chinese standards.
Shaanxi Province is one of China's biggest coal mining areas, but Xi'An, the provincial capital, is becoming a cradle of clean energy technology development. It boasts 47 universities, more than any other Chinese city except Beijing and Shanghai, and this provides a strong source of human capital for its new High-Tech Zone.
We sat down with General Manager of Applied Materials' Solar Technology Center Dr. Ruiping Wang during our visit to talk about other elements that make Xi'An, and China in general, attractive as the site of its solar research and development efforts.
Excerpts of the interview are in the video above.
Julian L. Wong is a Senior Policy Analyst for the energy policy team and Sarah Miller is the Policy Advisor to President and CEO John Podesta.
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6 Responses to Applied Materials comes to XiAn
Nice interview and post despite being low on details.
Surface discussion of achievements and strategies:
Guns into plowshares as Applied Materials' original business was for the military now civilian use.
High investment in human capital with lots of universities
Government support for infrastructure and clean energy strategies in photovoltaic (pv) and light emitting diode (led) technologies.
Indication that the government is trying to establish a large national and multinational research and development center for clean energy.
No mention of nanotechnologies also of the materials science field with the potential for being disruptively positive game-changers leading to dramatic built environment and clean energy developments on the scale of the electronics, computer and communications revolutions; with typically dramatic economic potential.
Moving green jobs to China. Thanks for letting us know.
China is the world's source of rare earth metals, some of which are essential components of "green technologies", computer hard drives, cell phones, etc. China is also reducing global access to its rare earth metals and processed oxides and intends to use these vital resources for domestic production of finished products which the world will have to purchase. That will include wind turbines and cfcs and leds.
It is no mystery why "green tech" companies are locating to China. That is how they will acquire the materials needed to build their products. The interviewer should have touched upon this or at least explore it before the team leaves China.
John McCormick
But all we have to do is put a $15 price on carbon, and then we will be good to go–right?
"Serious Materials?"
Anyway, Applied materials has a pretty neat vision for solar, see http://fab2farm.appliedmaterials.com/
Just need some money and some cities to bite ….
So, turn your back on your own country, because you can get engineers for $730/month….well, you get what you pay for.


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2 Cans Diced Potatoes1 Can Corn1 Can Creamed Corn2 Cans Sweet Peas1 Can Rotel (or diced tomatoes)1 20 oz Ketchup16 oz. bottled water2 lbs Meat (Any cooked meat will do.)16 oz BBQ Sauce1 tbs Worcestershire SauceSalt and Pepper to taste
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Deathmatch Village has PS3 Vita Cross-Play
Bloober Team has announced Deathmatch Village, a free-to-play multiplayer affair headed to PlayStation 3 and Vita. Eurogamer reports the 3v3 arena combat title offers Cross-Play, Cross-Save and dozens of weapons. No screens or video as yet. Blooper was last seen working on Medium; the developer is all that remains of Nibris, the team behind unreleased Wii title Sadness, and also produced A-Men.
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Levels of Life
This short, unconventional book is probably the most moving that Julian Barnes has ever written
You put together two things that have not been put together before. And the world is changed…
In Levels of Life Julian Barnes gives us Nadar, the pioneer balloonist and aerial photographer; he gives us Colonel Fred Burnaby, reluctant adorer of the extravagant Sarah Bernhardt; then, finally, he gives us the story of his own grief, unflinchingly observed.
This is a book of intense honesty and insight; it is at once a celebration of love and a profound examination of sorrow.
2 Reader ReviewsSee All Reviews
Editorial Reviews
"It is extraordinary... [It] would seem to pull off the impossible: to recreate, on the page, what it is like to be alive in the world." - Emma Brockes, Guardian
"This is a book of rare intimacy and honesty about love and grief. To read it is a privilege. To have written it is astonishing." - Ruth Scurr, The Times
"It's an unrestrained, affecting piece of writing, raw and honest and more truthful for its dignity and artistry... Anyone who has loved and suffered loss, or just suffered, should read this book, and re-read it, and re-read it." - Martin Fletcher, Independent
"Levels of Life is both a supremely crafted artefact and a desolating guidebook to the land of loss." - John Carey, Sunday Times
"While one might expect a Barnes book to impress, delight, move, disconcert or amuse, the last thing for which his work prepares us is the blast of paralysingly direct emotion that concludes Levels of Life." - Tim Martin, Daily Telegraph
"Levels of Life is, deep-down, a heartfelt attempt to chronicle the strange journey that follows the death of a loved one." - Craig Brown, Mail on Sunday
"A Taj Mahal made of paper not white marble." - Peter Conrad, Observer
"A magnificent blast of unflinching prose." - Daily Telegraph
"A magnificent blast of unflinching prose." - Daily Telegraph
"Powerful and well-articulated." - Roger Lewis, Daily Mail
About the authorMore
Julian Barnes
Julian Barnes is the author of twelve novels, including The Sense of an Ending, which won the 2011 Man Booker Prize for Fiction. He has also written three books of short stories, Cross Channel, The Lemon Table and Pulse; four collections of essays; and two books of non-fiction, Nothing To Be Frightened Of and the Sunday Times Number One bestseller Levels of Life. He lives in London.
Julian Barnes BooksMore
- A History Of The World In 10 1/2 Chapters (Vintage Past)
by Julian Barnes
Vintage Past: Inventive tales of times gone by to tell the histories we think we know
- The Noise of Time
by Julian Barnes
Art and Power collide in Julian Barnes's first novel since the Booker-winning The Sense of...
- Keeping an Eye Open: Essays on Art
by Julian Barnes
A collection of essays on art by one of Britain's most brilliant writers.
- Through the Window: Seventeen Essays (and one short story)
by Julian Barnes
From one of Britain's greatest writers comes a brilliant collection of essays on the write...
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Dennis Helder
Position Title: Associate Dean for Research
Department: College of Engineering
Area of Research: Radiometric, Geometric and Spatial Calibration of Satellite and Airborne Optical Sensors
What motivates you about your chosen field?
I found that I really enjoyed image processing when I was in graduate school. Having USGS EROS, the largest archive of land satellite imagery in the country, just down the road from SDSU gave me the opportunity I wanted to work with images. Calibration converts those images from pretty pictures to accurate data sets that can be used for a variety of scientific purposes such as global change monitoring, deforestation, water management, and many others.
Why did you choose to conduct your research at SDSU?
I was born and raised in this area. So it's fun to work at home, yet do high tech research!
What roles do your colleagues and student research assistants play in the work you do?
Our research lab works as a team. We have staff members, as well as several students, working together to solve satellite calibration problems. Everyone brings something to the table and it's fun to integrate it all together to accomplish the tasks we are funded to address.
What have been some of your greatest research accomplishments while at State?
The most recent one occurred about a year ago when we developed a consistent calibration for the entire Landsat archive. Landsat sensors have been in orbit since 1972 and eight different instruments have collected images of the earth's surface from then until now. However, the sensors were not calibrated to a consistent radiometric scale. We completed that calibration—it took us about 10 years—this past year so that now scientists can use Landsat images from 1972 and compare them to images of the same location obtained in 2012 and be assured that the changes they see actually are due to changes on the Earth rather than changes in the satellite sensor.
What do you enjoy most about SDSU?
Working with the faculty and students. I have always been impressed with the faculty I have been blessed to work with. They are genuinely good folks that enjoy working for the benefit of students and their profession. Students are great, too. They help keep us more 'mature' faculty young in our perspectives and always bring new ideas to the table.
What piece of advice would you give new students?
Get to know your professors. They are people, just like you, and are here because they want to work with students.


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Translation of insanity in Spanish:
- 1 (madness)Example sentences
- In practice, the effect of this strict approach has not been greatly to swell the numbers of people pleading insanity.
- There's something about this place that breeds great madness and insanity.
- The trial judge ruled that this was a defence of insanity, whereupon she pleaded guilty and appealed.
- 2 (foolishness)Example sentences
- But the show does capture the various insanities and absurdities of his life, and is filled with clips of his more outrageous outfits.
- Sarcasm raises its ugly head between all your sacred rites and ceremonies, but you cling on to your methodical insanities.
- Yet, one has to wonder how National, despite the multitude of Labour insanities, only leads by one point.
Definition of insanity in:
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Programme Highlights
MENTOR's RESPONSE TO THE LEISHMANIASIS EPIDEMIC IN SYRIA » The Syrian conflict and vast population displacement has significantly increased the vector-borne disease, leishmaniasis, within Syria. Poverty, malnutrition, displacement and a weakened health system are all risk factors for leishmaniasis. Find out what MENTOR is doing to control leishmaniasis here.
Zika » MENTOR is providing technical support to UNICEF and IFRC to help guide the teams in the Americas in the Zika responses and is planning further support at country level.
Proud to support Mediaplanet's The 2016 Malaria Campaign. The campaign is distributed through The Guardian newspaper on 25th April, distributed at world leading events and is published online on www.malariaawareness.co.uk. Over 15 million people today are being reached through – together we can #EndMalaria. Read the interview with CEO of MENTOR, Richard Allan here
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text: My project page on the front end is only showing 5 projects with 5 tasks each. I have 6 active projects, each with more than 5 active tasks. Is there a way to show everything? Is this something I need to fix in one of the themes or a selection I make somewhere?


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Start your day with our Signature Breakfast, and enjoy traditional café classics enlivened with a modern twist. Along with our complementary Eye Openers, these distinctive offerings awaken the senses with an infusion of local flavours.
Le Méridien Hub, our innovative hotel lobby concept, is a coffeehouse-style gathering place for creative minds. Enjoy an illy espresso crafted by one of our Master Baristas, or indulge in an éclair while discovering a playlist curated by French bossa nova band "Nouvelle Vague."
With our Unlock Art™ programme, keycards unlock more than just doors; our partnerships provide access to leading contemporary culture centers in every destination. In the evening, join us for Le Méridien Sparkling, a cocktail ceremony inspired by the traditional European aperitif hour.
The hotel only serves alcoholic beverages to those guests 18 years or older, with valid identification.
Guests must be 20 years or older with valid photo identification to reserve and check-in to a room.
The hotel provides babysitting services at a charge for our guests' convenience. Reservations are required at least two days in advance.
The hotel regrets that checks are not accepted as a form of payment.
The hotel offers Executive Suites with a king bed that can connect to a Deluxe Twin or Executive Deluxe Twin with two single beds. Connecting rooms must be requested in advance and are subject to availability. We recommend that guests contact the hotel to confirm availability.
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The hotel will apply a full day charge for guests checking-in at 11am or earlier.
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The hotel regrets that pets are not allowed.
A third party wishing to pay for a guest's room in the hotel must complete an Authorization Approval Form and fax/e-mail a clear copy of the front and back of the credit card prior to the guest's arrival. Please specify which charges can be charged to the credit card. Please contact the hotel for more information.
Local ordinance prohibits smoking in all areas of the hotel including guest rooms, restaurants, function rooms and all public areas. Violators of the ordinance will be fined 2,000 TWD to 10,000 TWD. For the convenience of our guests, one comfortable smoking area have been established in the hotel—the 3F Smoking Room.


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In this year's Chicago Triathlon I swam faster and biked faster than I ever did during training, without really "pushing" it. However, my run was about a minute and a half slower per mile than I was running during training runs...I started slowing way down at about mile 3.
I am wondering if my training caused this. During brick training I would ride the full bike distance but then only about 2-3 miles of running followed. I would, of course, run the full distance regularly during training, just not in the brick.
I have some pretty aggressive improvement goals for the 2006 season. Any suggestions on how to finish stronger?
What did you do for intake? Any jel or gu? Hydration an issue? That sounds like more of a cause than training or experience.
Training wise, I would add some hills. Some nice mean bastards. Perhaps start your run off a little easier, get your legs and then go to cruising speed.
I had the same experience in Chicago this year. After reviewing the race over and over again I came to the conclusion that nutrition and lack of warm weather training did me in. I finished but my run was a minute and half slower per mile than normal. I used GU and water during the bike but held off using a sports drink because they sometimes cause digestive problems. This was a big mistake because the weather turned deceptively warm for the late morning start times. The temp jumped at least 15 degrees following the water start (and hit the high 80's) and the sun really baked the bike and run path. Two other participants collapsed on the path as well. I'm interested to hear others experiences at Chicago this year. Any similar stories? If not, what was your nutrition intake and training set up?
I too was a late start and that affected my run. All the waiting till my number was up kinda wore me out. I ate gel on the bike and only drank water. Digestive problems with gatorade or sugar. I belive the heat cause some slowing down for me.
ACTIVE is the leader in online event registrations from 5k running races and marathons to softball leagues and local events. ACTIVE also makes it easy to learn and prepare for all the things you love to do with expert resources, training plans and fitness calculators.


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Cartoons Featured on Battery Pop Patrick Neary's animated cartoons are rolling out on Battery Pop, the new kids' programming network. Check them out at www.batterypop.com and vote with a POP!
The City of Hillsboro was one of 20 finalists for Bloomberg Philanthropies Mayors Challenge, a nationwide contest to drive innovation in local government. Our animation department created a video to illustrate Hillsboro's winning concept – GoPoint.
"Which film one was your favorite?
'Cowburd! It was SO AWESOME!!'"
"Cowburd was great! It was all the kids could talk about after the screening."
"Martian Picnic was a huge success at our festival! Kids wanted to see it twice so we played it again after all the others. They laughed loud, jumped up and down by the screen and one kid kept yelling "one eyed monster, one eyed monster!" over and over!"


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Velvet Zardozi Pillow Cover
An embroidery technique once reserved for royal robes, zardozi creates shimmering designs with tiny coils of metallic thread. Paired with deep blue velvet, the effect is rich and regal. Made from cotton rayon velvet. Hand embroidered with silvery metallic thread. Reverses to solid blue velvet. Hidden zipper. Insert sold separately. 12" x 16".
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General Services Administration CIO Sonny Hashmi. (FCW photo by Zaid Hamid)
The General Services Administration has melded an "open source first" policy with the federal government's cloud-first policy to develop a list of nine key principles the agency's CIO says will guide its IT operations into the future.
GSA Chief Information Officer Sonny Hashmi said the nine principles should be incorporated into all of the agency's new IT builds or enhancements. "These principles will guide us as we continue to modernize our organization, processes, technologies and platforms at GSA," he wrote in an Aug. 1 blog post.
In addition to open source first and cloud first, the other principles are:
On platform reuse, Hashmi said that GSA has spent money over the past few years on common application and infrastructure platforms to allow rapid deployment, reuse of resources and cost-effective delivery of business services. The platforms reuse common components and technologies to cut IT costs and complexity by reducing the number of applications and tools its end users need to learn and access, he said.
What 18F aims to accomplish
Former Presidential Innovation Fellow Clay Johnson, a frequent critic of the federal procurement system, praised GSA's effort to become a touchstone for open source. "I think it's a great thing. The GSA and the 18F team are doing remarkable things demonstrating to the rest of government how it should be done," he said.
Gunnar Hellekson, chief technology strategist at open source solutions provider Red Hat US Public Sector, concurred.
"This really is the GSA adopting industry best practices. Commercial companies evaluate open source as a matter of course. It's just standard operating procedure. It's wonderful to see the GSA join its commercial counterparts in taking advantage of everything open source has to offer," Hellekson said.
"One challenge GSA will face is having the talent and expertise to use all the open source available," he said. "Groups like 18F can help build capacity, but the GSA will also be relying on commercial open source vendors and system integrators that can take some of the sharp edges off these cutting-edge products."
While the GSA is known for being an early adopter of the government's cloud first initiative, its use of open source software is relatively new. "Simply put, any solution developed by taxpayer dollars should be in the taxpayer's domain," Hashmi said. "At GSA, we believe that all code we developed should be shared under an open license so others may benefit from it. In addition, we will give priority to using open source software as we design new solutions."
Hashmi's open source software pledge comes after the agency unveiled its 18F tech innovation program a few months ago, and marks a further solidification of the agency's efforts to be more flexible and innovative in the sometimes-stolid and prescribed world of federal procurement.
About the Author
Mark Rockwell is a staff writer at FCW.
Before joining FCW, Rockwell was Washington correspondent for Government Security News, where he covered all aspects of homeland security from IT to detection dogs and border security. Over the last 25 years in Washington as a reporter, editor and correspondent, he has covered an increasingly wide array of high-tech issues for publications like Communications Week, Internet Week, Fiber Optics News, tele.com magazine and Wireless Week.
Rockwell received a Jesse H. Neal Award for his work covering telecommunications issues, and is a graduate of James Madison University.
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The agency software inventories required under the draft category management policy will be treasure maps that lead to efficient, effective, streamlined buying and unprecedented savings.
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The agency is making strides in developing and deploying border technologies but still has some weaknesses.
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The United Kingdom will go live with its governmentwide digital identity platform, GOV.UK Verify, in the coming days. The U.S. government will need a little more time.
What contracting officer representatives really think is needed to fix contract management.
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Hello! I am using your plugin for the gallery on my website http://grabkovadeiloff.com/projects/, and appreciate it very much, but there are some issues. First - the lightbox continues cycling after last image in gallery 1 to first in gallery 2.
Could you perhaps implement some solution? http://wordpress.org/extend/plugins/lightbox-gallery/ This plugin actually can separate multiple galleries by adding "class=gallery1" to gallery shortcut.
The second issue - the shortcut fsg_photobox does not work in wordpress post tabs, which I am using.
Thank you very much for your work!


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+ Post New Thread
First off, congratulations on your release and thanks for a great product! I'm very excited to see where things go from here. :D
I have a...
Create a panel, absolute layout.
Add a textfield to this panel, remove the anchor property so it won't stretch. set the width and move it to where...
Designer version tested:
Designer 220.127.116.11c
Operating System:
WinXP Media Center Edition
Designer version tested:
Designer 18.104.22.168c
Operating System:
Mac OS/X 10.6.3
When I add a DataView in the designer the...
I'm evaluating the ExtDesigner and so far I'm pretty positive - good job! However when building up demo projects, I have quite some issues with...
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Designer version tested:
Designer 184.108.40.206c
Operating System:
WinXP Pro with SP3
The scenario: I have two buttons centered in a vbox. By default, their flex properties is set to '1' which distances them from each other. Setting...
UPDATE: sorry, just noticed this is already reported.
I've created a store and for the baseParam I just entered an empty object (I know...
I can't register Ext Designer on Snow Leopard, I'm assuming it's because i'm behind an authenticated proxy.
Ext Designer should support from the...
Designer version tested:
Designer xds-18.104.22.168c
Operating System:
Mac OS X Snow Leopard
On entering
the designer generate an error saying that Profile is...
Ext designer: 1.0.10c
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After filling in an Ext Direct API that cannot be found, an error message is shown, but behind the panel....
Designer: 126.96.36.199c
OS: Mac OSX 10.6.3
the code generator is not putting a trailing comma (",") after the baseParams element:
what is...
Ext Designer version xds-188.8.131.52c.
the "clicksToEdit" property is not in the Component Config property list for an Editor Grid Panel
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Drag a container onto the design area. Drag a toolbar onto that. It won't drop.


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Helping you give personalized, sophisticated gifts, from the heart, without sophisticated effort .
Welcome !I'm Kelli Belt. I enjoy helping folks create photo gifts that honor others , celebrate events, or tell their stories so uniquely they leave others speechless. All with 2 ordinary photos. The perfect gift for the person who has everything !


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Mary Pace Hill
Published: Thursday, November 1, 2012 at 7:35 a.m.
Last Modified: Thursday, November 1, 2012 at 7:35 a.m.
HENDERSON COUNTY — Mary Johnson Pace Hill, of East Flat Rock passed away Friday, October 5, 2012 at Pardee Hospital following a period of declining health. A native and lifelong resident of Henderson County, she was a daughter of the late Jesse Turner and Lucille Pressley Johnson, and the wife of the late Weston Hampton "Dub" Pace, and the late Julian Hill. She was also preceded in death by her brother, William Clarence Johnson, and her sister, Sibyl J. Moffit.
Mary retired after forty-three years of service with the Tuxedo factory last owned by West Point Pepperell. She was a member of the Order of the Amaranth in Hendersonville, and Tuxedo First Baptist Church. Mary supported many local organizations including the Shriners Hospitals for Children in Greenville, SC, Kedron Masonic Lodge, the Saluda Masonic Lodge, and the Order of the Amaranth.
It was Mary's request to have no memorial service, and to be interred beside of her first husband, Weston "Dub" Pace at Forest Lawn Memorial Park.
Forest Lawn Funeral Home assisted Mary with arrangements.
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Guide to Find our best travel tips, advice and inspiration on what to do and where to stay in our guide to Podgorica. Discover how to travel on a budget and don't forget to check the weather before you go!


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Department: Microbiology & Immunology
Dr. Mehta is a professor in the Department of Microbiology & Immunology at Drexel University College of Medicine.
Research interests: Development of new hepatitis B (HBV) therapeutics; identification of early markers of liver cancer.
Graduate students: Anne Lamontagne and Yuanjie Liu
The hepatitis B virus (HBV) is the prototypic member of the Hepadnaviridae family of viruses that chronically infects 350 million people worldwide. The major complication is the development of primary hepatocellular carcinoma (HCC) estimated to cause 500,000 deaths annually. Although there is no cure for HBV infection, several therapeutic options exist. However, the poor response rate and development of resistant mutants highlight the need for alternatives and complements to the conventional therapeutic regimens. Our laboratory has two major projects: the development of new HBV therapeutics and the search for early markers of liver cancer and cirrhosis. Our approach towards the discovery of HBV therapeutics involves the development of immunological agents to complement traditional anti-virals. That is, there is a growing body of evidence that animals and people chronically infected with hepadnaviruses possess the potential to mount a beneficial immunological response to the virus. It appears that this response, in experimental animals and in chronically infected people, can be enhanced or enabled by highly effective and sustained antiviral therapy and vaccination using hepadna viral antigens (Boni et al. Hepatology. 33: 963 2001). Thus, our approach involves the development of novel HBV DNA vaccines that will be able to generate the appropriate immune response to help cure people of HBV. This work will lead to great insights into the basic biology of protein folding, degradation, antigen presentation and into the development of useful therapeutic products. In an effort to identify serum biomarkers of HCC, we have developed a targeted glycoproteomic approach. That is, we have utilized a simple quantitative method to identify alterations in glycosylation and subsequently identify the glycoproteins with altered glycosylation, by two-dimensional proteomics (2DE). In the case of primary HCC, we have shown that an increase in the fucosylation of liver derived glycoproteins is associated with the development of cancer. By combining our quantitative glycan sequencing methodology with 2DE, we have identified many glycoproteins with altered glycosylation as a function of disease. One such glycoprotein, GP 73, was found to be elevated and hyperfucosylated in animals with HCC. Further analysis of human sera from patients with varying disease states confirmed the specific association of GP73 with the development of HCC. GP73 is a resident Golgi membrane protein that is known to be upregulated in liver disease including viral infection and, although its function has yet to be elucidated, its expression profile suggests it may serve as a biomarker of liver cancer.
Selected Research Publications
"Identification and development of fucosylated glycoproteins as biomarkers of primary hepatocellular carcinoma"
Comunale MA, Wang M, Krakover J, Rodemich L, Kopenhaver B, Long, RE, Junaidi O, Di Bisceglie AM, Block TM, and AS Mehta.
Journal of Proteome Research. 8(2): 595-602, 2009.
"Glycomic Characterization of Prostate Specific Antigen and Prostatic Acid Phosphatase in Prostate Cancer and Benign Disease Seminal Plasma Fluids"
White KY, Rodemich L, Nyalwidhe JO, Comunale MA, Clements MA, Lance RS, Schellhammer PF, Mehta A, Semmes OJ, and RR Drake.
Journal of Proteome Research, 8(2): 620-630, 2009.
"Inhibition of cellular alpha-glucosidases results in increased presentation of hepatitis B virus glycoprotein peptides by MHC class I"
Simsek E, Sinnathamby G, Block TM, Liu Y, Philip R, Mehta AS, and PA Norton.
Virology, 384(1): 12-15, 2009.
"Glycoproteomic analysis by two-dimensional electrophoresis"
Comunale MA, and A Mehta.
Methods Mol. Biol., 520: 59-74, 2009.
"Analysis of GP73 in combination with fucosylated alpha-1-antitrypsin and fucosylated kininogen as a biomarker of hepatocellular carcinoma"
Wang M, Long RE, Comunale MA, Junaidi O, Marrero J, Di Bisceglie, AM, Block TM, and AS Mehta.
Cancer Epidemiology, Biomarkers & Prevention, 18(6): 1914-1921, 2009.
"Increased levels of galactose-deficient anti-Gal immunoglobulin G in the sera of hepatitis C virus-infected individuals with fibrosis and cirrhosis"
Mehta AS, Long, RE, Comunale MA, Wang M, Rodemich L, Krakover J, Philip R, Marrero JA, Dwek RA, and TM Block.
J. Virol., 82(3): 1259-1270, 2008.
"Human immunodeficiency virus-related microbial translocation and progression of hepatitis C"
Balagopal A, Philp FH, Astemborski J, Block TM, Mehta A, Long R, Kirk GD, Mehta SH, Cox AL, Thomas DL, and SC Ray.
Gastroenterology, 135(1): 226-233, 2008.
"N-linked glycosylation of the liver cancer biomarker GP73"
Norton, PA, Comunale MA, Krakover J, Rodemich L, Pirog N, D'Amelio A, Philip R, Mehta AS, and TM Block.
J Cell Biochem., 104(1): 136-149, 2008.
"Fucosylated Biomarkers for liver fibrosis, cirrhosis and cancer"
Mehta A, and TM Block.
Dis. Markers, 25(4-5): 259-265, 2008.
"A Substituted Tetrazolo-Pyrimidine is a Specific and Novel Inhibitor of Hepatitis B Virus Surface Antigen Secretion"
Dougherty AM, Guo H, Westby G, Guo J-T, Mehta A, Norton P, Gu B, Block TM, and A Cuconati.
Antimicrobial Agents and Chemotherapy, 51(12): 4427-4437, 2007.
"Lectin capture strategies combined with mass spectrometry for the discovery of serum glycoprotein biomarkers"
Drake RR, Schwegler EE, Malik G, Diaz JI, Block T, Mehta A, and OJ Semmes.
Mol. Cell Proteomics, 5(10): 1957-1967, 2006.
"Proteomic analysis of serum associated fucosylated glycoproteins in the development of primary hepatocellular carcinoma"
Comunale MA, Lowman M, Long, RE, Krakover J, Philip R, Seeholzer S, Evans AA, Hann HW, Block TM, and AS Mehta.
J. Proteome Res., 5(2): 308-315, 2006.
"Use of targeted glycoproteomics to identify serum glycoproteins that correlate with liver cancer in woodchucks and humans"
Block TM, Comunale MA, Lowman M, Steel LF, Romano PR, Fimmel C, Tennant BC, London WT, Evans AA, Blumberg BS, Dwek RA, Mattu, TS, and AS Mehta.
Proc. Natl. Acad. Sci. U. S. A., 102(3): 779-784, 2005.
"Hepatitis B Virus Large and Middle Glycoproteins Are Degraded by a Proteasome Pathway in Glucosidase-Inhibited Cells but Not in Cells with Functional Glucosidase Enzyme"
Simsek E, Mehta A, Zhou T, Dwek RA, and TM Block.
J. Virol., 79 (20): 12914–12920, 2005.
"GP73, a resident Golgi glycoprotein, is a novel serum marker for hepatocellular carcinoma"
Marrero JA, Romano PR, Nikolaeva O, Steel L, Mehta A, Fimmel CJ, Comunale MA, D'Amelio A, Lok AS, and TM Block.
J. Hepatol., 43(6): 1007-1012, 2005.


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By Spc. Elizabeth GorencAugust 27, 2008
CAMP ATTERBURY, Ind. (Army News Service, Aug. 27, 2008) - The legacy of a World War II prisoner of war lives on through a rock that marks the entrance of Camp Atterbury. Libero Puccini, one of the crafters of that monument, recently passed away.
Col. Barry Richmond, Camp Atterbury commander, said that Camp Atterbury was blessed by the opportunity to share Libero's life.
"That big stone that Libero carved over six decades ago still marks our entrance. And it stands not only for our legacy of traditions in training excellence, but as a promise to the future that Camp Atterbury will remain a premiere training center."
Puccini and thousands of other Italian Soldiers were brought to Camp Atterbury in 1943, as prisoners of war after surrendering to American troops.
While here, the Italian POWs were hired out to local farmers and tomato canneries. When not working, the POWs completed special projects to pass the time. Two of those special projects, the POW Chapel and Camp Atterbury entrance stone, still stand today serving as memorials to the war prisoners.
While hundreds of POWs worked together to build the chapel, only Puccini and one other Italian were selected to carve the colossal rock to sit near the front gate of the camp.
Retired Col. Jorg Stachel, a former Camp Atterbury commander and friend of Puccini's, said the commander at the time was looking for someone to complete the project for the entrance and sought out Puccini.
"Puccini was quite an artist so it was no surprise that he was approached with the task," he said. "Every time I pass that rock, I think of Puccini."
In an anecdote from The Atterbury Files, a reference book about the camp written by Custer Baker Middle School students in the 1980s, Puccini said some of his most interesting experiences as a POW at Camp Atterbury were attributed to being involved in that special project.
The project was an "exercise of artistic skill that would mark the entrance of the camp, the date of its establishment and symbolic sword on a large glacial stone," he said.
Puccini said in the article that the project could have been accomplished in two weeks time but he extended the process.
"I was assigned another POW to work with me. Having not much to do and being it was a pleasant summer we decided to do a little goldbricking and prolonged the enterprise for the rest of the summer," he said.
"The rock is now in a prominent position where I hope it will remain as a memory of the time," said Puccini, in The Atterbury Files.
"The Atterbury Rock" has attained a certain fame in the local area. Just as his biography states, it has become the face of Camp Atterbury, used on plaques and official photos as well as its Web site; and just as he hoped, the rock remains and will continue to be a reminder of the Italian POWs' contribution to the installation.


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"Old saved by New..." Top 5 Page for this destination Chicago Favorite Tip by deecat
Chicago General: 445 reviews and 517 photos
Favorite thing: I pointed out the beautiful Carbide and Carbon Building to Allan. This building with its polished black granite and marble base is 40 stories high and uses glazed green terra cotta. It's topped with a gold Art Deco leaf-trimmed tower that is illuminated at night.
The Carbide and Carbon Building was completed in 1929, and it resembles a champagne bottle. In 2004, it was renovated and became the Hard Rock Hotel. Allan and wanted to see what it looked like inside so we casually walked inside as though we were staying there. Once inside, we sat down on the comfortable modern couches and observed. The interior is quite modern and follows what one would expect of the Hard Rock Franchise.
The Hotel is located at 230 North Michigan Avenue and attracts a much younger crowd. I'm so pleased that this lovely old building and its grand architecture was really saved by the "hip" Hard Rock Hotel.
#1 I took this photo of the outside of the Carbide & Carbon Building very up close and from the bottom up at a slight angle.
#2 This photo was taken inside the Hard Rock Hotel. As we walked in, we turned to the right and made ourselves comfortable at this small bar/seating area.
Allan thanked me for giving him the "scoop" on this Carbide and Carbon Building, which has become The Hard Rock Hotel.
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On top of Mickey Mouse, Cinderella and Aladdin, visitors to Disney theme parks may one day get a glimpse of drones.
Walt Disney Co. appears to have a wish to use unmanned aircraft to produce entertainment shows, according to three recently published patent applications first reported by the blog Stitch Kingdom.
At the moment, aerial shows can be cumbersome and difficult to modify, Disney says in the applications published last week.
The shows may rely on "very complex fountain systems," fireworks or even blimps dragging large display screens, an application reads. Light shows can also be projected onto buildings, another filing says.
But buildings can't be moved, fireworks can be dangerous and water can shoot only so high, limiting the size and scope of the shows, the applications say.
Disney's apparent fix? Drones. What else?
Numerous drones would jet through the sky, carrying "display payloads" to create a "dynamic display," according to one application.
"Each of these (drones) with its display payload may be thought of as a floating pixel or 'flixel' that when combined provides a very large display screen or aerial display that may be three dimensional," the patent application says.
Another application has a hint of Pinocchio. Drones, the document reads, would pull the strings on marionettes, moving their limbs.
Another patent application says drones would carry flexible, floating projection screens to present "an aerial display over an audience of spectators."
A representative from Disney could not immediately be reached for comment.
Location, ST | website.com


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I would like to use the Google URL Shortener in Google Chrome. Has anyone figured out or heard of a way to do this yet?
Here is their release announcement, it is only available for Google Toolbar and Feedburner. And to quote the post
With all that said, I did find this extension for chrome


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Passion on the Playa: The Best Burning Man Missed Connections
"Your name is David, your playa name goblin?"
If you're not ready to commit to a self-marriage, perhaps you were looking for love on the playa at Burning Man last week. A few hopeful souls on Craigslist certainly were, but their budding desert romances were quickly derailed by robot hearts and horse sailboats. Come take a journey with us through the spiritual arena of Burning Man Missed Connections. (My playa name is Cat Princess.)
"looking for John from Half Moon Bay--we met Saturday at Burning Man" w4m (430&G)
If you're a handsome, dark-haired man named John, this lady was wowed by you after you offered her "a gift containing googly eyes."
"i tried to find you at the fallout shelter later," she writes, "but they'd never heard of you."
"lindsey you rode my art cart twice at burning man" m4w (new york)
Lindsey, this guy wants to "know what your film is about" and also probably make out.
"I lost you at burning man" w4m
A woman with long, wavy hair dressed in a belly-dancing outfit is seeking her Prince Charming, a man named "Goblin" who "rode the robot heart" with her. Burning Man sounds mad romantic.
"'Brother' with the chai tea cart in deep playa" m4m
This one is so good it deserves to be reprinted in its entirety:
On Friday night we met you in deep playa. You were serving chai tea from a cart you built yourself and brought out on a tandem bike, in exchange for either two compliments or a secret. You were also dispensing free spiritual advice. Your playa name was Brother and you said you were from Berkeley.
There were three of us. You told us that your favorite teacher said that you never *have* to do anything and can choose to do what you do.
We thought you were really cool and wanted to connect in the default world!
Here is our fee:
1) your chai was awesome
2) we thought you were really cool
May you all find each other, you lovable band of complete weirdos.


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Ready in 45 minutes
8 people want to try | 18 have favorited
Saute onion, mushroom stems, and crabmeat in butter until onion is transparent.
Mix in salt, pepper, parsley, basil, lemon juice, Worcestershire and Tabasco.
Add flour, and cook over medium heat about for 5 minutes, stirring frequently.
Slowly add milk, whisking constantly; mixture should be very thick.
Add Parmesan cheese, and cook over low heat, for 5 minutes longer, stirring constantly.
Remove from heat, and add wine as desired to taste, so mixture still remains quite thick, and then adjust all seasonings to taste.
Spoon into mushroom caps, and sprinkle with chopped almonds.
Bake at 350-375 degrees F for about 15 minutes or until top starts to brown a little, being careful that almonds do not burn.
Variation: I actually like this version better than the crab!
Replace crab with 8 oz cooked shrimp, peeled, deveined, and chopped.
It's just a matter of preference, but I like it!


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Spencer's Orchard & Greenhouse in Harrah has been family owned and operated since the 1960s. Bring the whole family ... read more...
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breathtaking longji rice terraces
Travelling through China may be a challenge for some, but when Rachel Wasser was an Intrepid leader she loved helping her groups discover why the effort was worth it…
"A highlight of the Beijing to Hong Kong holiday is definitely the time we spend in Longji. This area is such a unique and breathtaking sight, it's hard to compare it to anything else!
one day in bangkok
What can you get for $10 these days? In most cities the answer would be "not much!" But Shelley Seale made it her challenge to spend less than this during a whole day in Bangkok…
"If you're traveling on a budget, South East Asia is a great place to do it. Once you get here, it's easy to keep the cost of living very low, and have an amazing time on just a few bucks. Take your pick from our recommendations to build your itinerary for a great day in Bangkok, for less than $10 – and easily around $5:
turkey for christmas
Considering the horribly harsh winter that the northern hemisphere is currently enduring, the concept of going in search of a white Christmas might seem slightly mad to some. But for an Aussie who's used to hitting the beach on Christmas Day, all Intrepid's Julie Keldoulis wanted was to explore East Turkey and see it snow…
"After asking many people and reading many guidebooks I decided on Erzurum [Arz-e Rum] (in Persian this literally means The Land of the Romans). Erzurum was known as 'The Rock', as it served as NATO's southeastern-most air force post during the Cold War. At 1757 metres above sea level, there are many reports about being the coldest city in Turkey. So why not go there I thought. Seems to have a lot of history as well as the near-by skiing resort on the Palandoken Mountain – the summit (Buyuk Ejder – Great Dragaon) reaching a height of 3188 metres.
top 5 must-sees of south east asia
When travelling through South East Asia you'll come across many amazing highlights and hidden gems. Jack Horder spent a few months doing just that and he's whittled the list of wonders down to his top 5…
"With the strong Aussie dollar continuing to linger and the reeling international tourism industry offering unprecedented deals, there has never been a better time to travel through South East Asia. A budget traveller's paradise, South East Asia offers a taste of the exotic as well as being a historical and culinary treasure. Here are just a few of my must-see destinations:
quito knows how to party
Every city has its celebrations, but the Fiestas de Quito is one of the world's biggest. From the end of November the streets overflow with music and mayhem and Intrepid's Summer Davis loved being amongst it all…
"For six days in the capital city of Ecuador, every night is a public party and for two days at the finale of this independence day revelry every business closes officially. This week most Quitenos partake of at least one chiva outing (traditional open-air bus painted bright colours), squished in the vehicle amongst drunken companeros belting out traditional Quiteno music along with the popular band on the bus roof.
art and craft of shopping in vietnam
Some people are inspired to visit Vietnam for its World Heritage-listed sites, intriguing local culture or even its delicious cuisine, but it was the promise of some serious retail therapy that tempted Intrepid's Lisa Rollinson…
"Vietnam has such an amazing variety of things to do and see but what convinced me to visit was the shopping. I was told it was great…but 'great' is a huge under statement. From ceramics near Halong Bay, to tailored clothes in Hoi An and incredible lacquer work throughout the north, I was in my element.
more to life in borneo
At any given opportunity our Intrepid team are off exploring all corners of the world, but you'll also find we each have our favourites that we love returning to time and time again. So we asked Intrepid's Jo Edgely to tell us about her special place…
"My favourite place in the world is undoubtedly Malaysian Borneo… I first went there as an Intrepid group leader back in 1999, and leading there for over three years, there was a point when I never thought I would leave. Now based in Melbourne, I make the journey every year to visit, because travelling in Borneo leaves you with a feeling that there is more to life, and that's something I always want to remember.
focus on ladakh
In July this year Lynne Yeaman joined a special Intrepid group travelling to Ladakh with professional travel photographer and renowned author, Steve Davey. Steve's photography tours are always a fantastic way to gain an insight into a destination, while having the opportunity to fine tune your photographic skills and feed off Steve's passion and enthusiasm…
"The fun began prior to departure with Steve forming a Facebook group for participants and it was like meeting old friends by the time we all arrived in Delhi!
mind, body and banya at lake baikal
What could be so uncomfortable about stepping into a sauna in Russia? Intrepid group leader Denis Sobnakov explains…
"One of my favourite places is Turka, a village on the shores of the beautiful Lake Baikal. With only a few people living here, this simple and very rural community can be considered one of the most peaceful places on the planet. But from time to time the quiet is disturbed with sounds of water splashing and people screaming. That's when you know an Intrepid group has arrived and they are experiencing their first Russian banya!
water festival in siem reap
This week there has been a lot of publicity about the tragic events at the Water Festival in Phnom Penh, Cambodia, where over 370 people were trampled to death in a stampede as the crowd became panicked. It was a tragic incident and our thoughts are with all those affected by the event. Thankfully we can confirm that none of our travellers and staff or their friends and families were involved.
Intrepid's Graham Stanley was in Siem Reap to visit our Cambodian office at the same time as the Water Festival…"The festivities here in Siem Reap were a lot less news-worthy and it was actually a fantastic occasion. The Water Festival is one of the largest festivals in Cambodia. The town was full of foreign visitors, as well as Cambodian tourists from other cities or the countryside wanting to be a part of the event.


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Coming up in January is the long-awaited debut release from this New York City swing band, and already the press is pouring in. Leader, vocalist and composer Svetlana Shmulyian has a fascinating life story which is covered in this interview.
Check it out and then buy a pre-release copy of Night At The Speakeasy now!
Lots of great airplay coming in for Origin and OA2 titles over the last several months, with Nick Finzer's The Chase (still in the Top 60 after 7 months at radio and 16 weeks in the Top 40!) leading the way. Ben Paterson's organ trio debut, For Once In My Life has been in the Top 60 for 2 months, and more recently, Tom Collier 's Across the Bridge with Bill Frisell and Larry Coryell, shot up into the Top 50 in it's 2nd week at radio and is getting widespread play across the country.
David Friesen and Glen Moore, two of the more influential bassists in jazz, recently teamed for a tour through Europe concluding with their 3rd duo recording over the last 40 years. Add the decade between their initial meeting up in Seattle in the '60s before their first recording, 1977's In Concert (Vanguard), and the total time they've been working together comes to 50 years. Named for the two-humped camel native to the steppes of central Asia, Bactrian offers ample new proof that these old friends continue to take great glee in surprising and challenging each other, their listeners, and themselves. Street date is November 20th, but look for it on sale here at the beginning of October.
Seattle vocalist Gail Pettis recently completed her second stellar tour of Russia over the last year. Playing to sold-out houses throughout central Russia, Pettis is developing material for her third recording in time for her next tour in Spring 2016.
With the amazing reception Laurie Antonioli received for her 2014 release, Songs of Shadow, Songs of Light: Music of Joni Mitchell, (including from Joni herself!), she decided to follow up with something entirely different. Rekindling a duo relationship she's carried on with master pianist Richie Beirach over the last 25 years, Varuna reveals the exhilarating musical empathy they've developed over that time. As Stereoplay magazine said about their last collaboration, "The delicacies created by (Beirach and Antonioli) are simply extraordinary." Varuna hits stores on September 18th.
Baritone saxophonist, composer and OA2 Records artist Aaron Lington was selected as a "2015 Silicon Valley Artist Laureate" by the arts organization Silicon Valley Creates.
He was recognized in the "Off Stage" category which celebrates his achievements as a composer and arranger.
This is the 25th year of the Silicon Valley Artist Laureate program and places Lington among 140 of the best artists in Silicon Valley from the last quarter century.
Gail Pettis is featured in October's MORE Magazine. Gail is profiled under the heading "Freeing Your Inner Artist" in the issue that's available on every newsstand in the country, now!
Paul Tynan has won the East Coast Music Award (ECMA) for jazz recording of the year for Bicoastal Collective: Chapter Three, from the ensemble he co-leads with Grammy Award-winning saxophonist Aaron Lington.
The awards were handed out in Charlottetown, PEI on April 6.
"Needless to say I am extremely excited about winning the 2014 ECMA jazz recording of the year award," says Tynan, who also played a showcase at the ECMAs.
Episode #30 of Origin Records Online Radio is no online at YouTube.
The episode is an interview with trumpeter Chad McCullough and talks about his up-coming shows and recent recordings Cascades and Lake Superior.
On May 19th 2013, the Metropole Orkest will be presenting a concert in Amsterdam celebrating the 50th anniversary of "Ballads." The performance will feature renowned tenor saxophonist Joe Lovano. The orchestra will be conducted by OA2 Records artist Daniel Jamieson, and they will be premiering his reimagined arrangements of these classic standards. In addition to the "Ballads" program, they will be performing arrangements by Jim McNeely, Joe Lovano, Kenny Werner and Billy Strayhorn.
Check out, Sudden Appearance, Daniel's debut release on OA2 Records.
New York trumpeter Liam Sillery received a 5-star review for his fourth and most recent release from OA2 Records. Phenomenology made a strong showing on the radio charts earlier this year, and is available now from our website. Don't miss this exciting record Downbeat's Chris Robinson states, "Is so natural, that only one word can be used to describe it: perfect."
Read the full review - here.