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Pizza #4
Tonight at Fondazione Gianfranco Ferré the special covers inspired by the work of the designer will also be on display
Tonight, at Fondazione Gianfranco Ferré in via Tortona, Milan, Pizza - the six-monthly magazine exploring Italian cultural identity and created by a team of under-30 headed by Sabrina Ciofi and Andrea Batilla and by Alessandro Jumbo Manfredini in the role of artistic director – will present its 4 issue.
Among the highlights of this issue is a journey through the archive of Germana Marucelli, one of the dress-makers who gave rise to the Italian style and a research into how India influenced the work of Gianfranco Ferré. Inspired by the "architect of fashion" is also the work of some young artists invited by Pizza to crate a special cover.
The presentation will start at 6 p.m in via Tortona 37, the headquarters of Fondazione Gianfranco Ferré which, as well as being a significant historic archive of the work of the designer, is also an authentic research centre concerned with the study of cultural changes related to aesthetics, style and image.
In the picture, the cover as seen by Sara Scanderebech
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Menswear and womenswear collections will walk together and will be on sale right after the show. These are the news from Burberry but the evolution is generalized: runway shows are changing


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Athletic Jackets and Hoodies
GapFit Athletic Jackets and Hoodies at Gap
Enjoy a variety of athletic jackets and hoodies for women from GapFit. Our athletic jackets are available in a variety of styles that can be mixed and matched with your running wardrobe. Athletic hoodies are designed specific for the rigors of a long run. We have a nice selection of cool weather apparel in this assortment available with zip fronts or as pullovers. Designed with comfort and great fit in mind, our jackets actually make your running and workout more fun because it looks so great. For the best in active outerwear, shop the selection at Gap.

subset: commoncrawl


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Working Stay At Home Mom
I was a stay at home mom for close to 2 years and a blogger for 9months. I need more income so I decided I needed to work. I was stressed out. I was unhappy. I wanted to do more for my child and myself. Staying at home is a job in itself. I applied and… Continue reading Working Stay At Home Mom


text: Hi All, I sent off my forms a couple of months ago to AOSB and am still awaiting a briefing date (medical issues). In those forms were three referees which included, for me, the coach of a sports club I am chairman of. Unfortunately, since sending off the forms things have turned a bit sour between the coach and the club, and I fear things will only get worse. Obviously this affects my relationship with the coach, being chairman, me having to deal with this coach and how he's behaving. Due to recent goings on, this guy possibly isn't a character I'd like to be associated with. So, my worry is that because of all of this he may provide me with a bad reference or not even provide one at all. Because of this, do you think it would be possible or even a particularly good idea to ring up AOSB and ask to change this referee? One, would they allow it? And two, how would this reflect on my application or would it have any adverse consequences on me being awarded a pass at Main Board? Many thanks, DM


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Is this an European restaurant?
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Thanks for helping!
Naples is interesting, sometimes the best restaurants are in nondescript strip malls. This is one of those. Fantastic for both lunch and dinner and just a short drive off of I75.
If your looking for some great French Cuisine, but don't want to pay the prices on 5th Ave- this is a great spot. Always new specials that incorporate local fish and flavors, but you'll also find your traditional favorites. Don't let the strip mall location fool you- the chef knows what he is doing. My favorite spot for French in...
My husband & I went on a whim to FAB, it was so wonderful, small and intimate, with the best food from hoemade france right here in Naples.
Lovely, ownera, Luc and his wife Lee(sp)
We had dinner and everyone participated in the dinner special. The salads were great, the dinners were not skimpy and dessert was good. The creme brulee was burnt on top and I was disappointed that they were still served that way but overall it was good and the service was outstanding.
Have wanted to try this place for a while and finally got to do it. Should have done it years ago. The small out of the way restaurant is a delight to the eyes and pallet. The staff went out of their way to explain the menu and we enjoyed every bite of dinner and dessert. The house wine was...
Our first visit will bring us back again. We opted to dine outside where our great server, Elicha, took good care of us. She knew her fond preparation and made some good suggestions. The veal special, escargot appetizer, and my rack of lamb were superb. (they even had mint jelly for the chops)
I went here with a small group. I ended up with Croque Madame (I'm a sucker for a fried egg). It was very good. we sat outside and enjoyed the Naples, sunshine. I'm listing this site as mid-range pricing, but the special was a good deal. I will go again.
The French American Bistro has a very fitting acronym: FAB! We've eaten there several times, lunch and dinner, and their food is reliably great. Always great service, and the menu is a nice blend of reliable fare and new items. Comfortable seating inside and out. Why not 5 stars? FAB is quaint and small, and it's not easy getting a...
Casual and cozy. Food was very good and proportions were generous (without overdoing things). My salmon was perfect and the veggies were steamed crispy.
Our waitress was sweet, efficient and not at all pushy when our table needed a few minutes to chat first.
I shy away from anything pretentious, and this Bistro was anything but.
My friend I stumbled on this amazing french restaurant.
Such nice and welcoming staff. My friend had a croque monsieur with a side salad that she enjoyed very much. I had the warm goat cheese salad which was delicious.
We shared a chocolate moose that was out of this world amazing.
Our waitress Dorine took such good care of us,we...
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Call (888) 651-9785
January 2017
Very great tour. Sam was our tour guide and he was extremely friendly and just chock full of information about the city. I would highly recommend to anyone. Super price for what all we got.
January 2017
great city lovely vibe to the place
January 2017
Although we had seen some of this the day before on the Hop On and Hop Off each driver is unique in their own interpretation. We got to spend time at previous Hop On and Hop off sites and revisit what we might have missed. Driver was very amusing and gave us new insight.
January 2017
Our tour director/driver, Sam, was wonderful. He showed us all the interesting and historical attractions. It was a great tour, and I would recommend taking this tour if this is your first trip to Memphis.
November 2016
The tour was excellent the bus arrived well on time and Sam the driver was very good he knew the area so well and he made the tour enjoyable and fun well worth booking..
November 2016
It was a very interesting tour and Willie was our guide and knew all about Memphis. Enjoyed it and would recommend this tour to travelers who want a good tour of Memphis.
Linda G Australia
November 2016
Sam our tour guide was very passionate about Memphis and was very knowledgeable and very friendly and entertaining. Great tour!
October 2016
Will remember this experience forever. Memphis is such a special place, people are amazing, not one complaint. Graceland was so sad and wonderful all in the same breath. If you are an Elvis fan you will understand once you walk into his home and his life.
Carol P United States of ...
October 2016
Great the whole tour from the Peabody, Beale St. Graceland and so much more
October 2016
We had a great tour with the Memphis city tour. Our tour guide Michelle was an absolute delight . She is very informative , she is very nice, she keeps you laughing throughout the tour and is very knowledgeable about the city . I would recommend anybody who can use Memphis city tours for any tour you need and if it is the city tour request Michelle as your tour guide you will not be sorry
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|Science & Medicine
The award winning Science Weekly is the best place to learn about the big discoveries and debates in biology, chemistry, physics, and sometimes even maths. From the Guardian science desk Ian Sample, Hannah Devlin & Nicola Davis meet the great thinkers and doers in science and technology. Science has never sounded so good! We'd love to hear what you think, so get in touch via @guardianaudio or [email protected]
February 19th, 2013
Episode 22 of 325 episodes
The second of our Nexus debates about the scientific, technical and social challenges of achieving sustainability in water, energy and food consumptionJo ConfinoJason Phipps
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Is Taska Permata Sirim Berhad incorrect or missing key business information? Update your Hotfrog listing today.
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Is Taska Permata Sirim Berhad in No. 1, Persiaran Dato Menteri, Seksyen 2, Shah Alam Selangor 40000 your business? Claim your listing and attract more leads by adding more content, photos and other business details.
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Aras 8 Menara Mrcb No 2 Jalan Majlis 14/10 Seksyen 14 Shah Alam Selangor 40000
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text:
Mohabbatein (2000)
( Bluray )
|Mohabbatein (2000)
|Rating: 7.1/10 (16,068 votes)
Director: Aditya Chopra
Writer: Aditya Chopra (dialogue), Aditya Chopra (screenplay), Aditya Chopra (story), Aditya Chopra
Stars: Amitabh Bachchan, Shah Rukh Khan, Uday Chopra, Jugal Hansraj
Runtime: 216 min
Rated: N/A
Genre: Musical, Drama, Romance
Released: 27 Oct 2000
Info: http://www.imdb.com/title/tt0213890/
|Plot: In India, open romance is forbidden, as is showing affection in public. A college principal named Narayan is a strong believer in this, aware that a male student named Vicky is in love with Ishika; while another male student is hopelessly in love with Sanjana; and a third man named Karan is in love with a married woman named Kiran. No amount of persuasion can get Narayan to change his mind. Then the college recruits a music teacher named Raj, who eventually starts fanning the flames of love among the students, much to Narayan's chagrin, anger, and displeasure. Things get worse when Narayan finds out that Raj was the very man who fell in love with his daughter who eventually committed suicide when he didn't grant them permission to get married. Will the six young people be also heartbroken by Narayan, and if so, who will be the first to kill himself or herself?
Jadwal Serial TV, Anime & K-Drama Buffering? Ada 2 Server silahkan pilih yang cepet. More Info Tekan CTRL+F5/Command+Shift+R jika Player tidak muncul Cara Download Film & Subtitle ada di F.A.Q & Fanpage
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Add retaggr.com functionality to your blog - image tagging of any image,and totally customizable Profile Cards.Demo and help at http://www.retaggr.com
Copy the retaggr folder and its contents to your wp-content/plugins directory, then activate the plugin.
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1180 West Peachtree Street, N.W., Suite 900
Atlanta, Georgia 30309
United States
|Areas of Practice
|1) Government/Litigation
|Law School
|University of Georgia School of Law
|University of Georgia (B.S.A., 2005
|Most recent firm
|Hall Booth Smith & Slover PC
|Relevant Jobs
Associate Attorney
USA-CA-Newport Beach
PUBLIC FINANCE AND GENERAL PUBLIC LAW ASSOCIATES We are an AV-rated law firm in Orange County, California specializing in public law for our local government clients since 1973. We desire to add ...
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Deputy District Attorney
USA-NM-Silver City
Seeking attorney in good standing to join dynamic team of state prosecutors focused on community based prosecution. IMMEDIATE OPENING for prosecutor to handle primarily Domestic Violence, Sexual ...
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Assistant General Counsel - Economic Sanctions
Assistant General Counsel - Economic Sanctions The candidate will report to the General Counsel for Economic Sanctions in the Corporate Legal Department. Will principally be responsible for providing...
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George A. Cumming is counsel in Morgan Lewis's Litigation Practice. He concentrates his practice on complex litigation across a wide range of substantive areas including antitrust, intellectual property, and financial services litigation.
Harry T. Robins is a partner in Morgan Lewis's Antitrust Practice. Mr. Robins represents clients, including a number of prominent private equity firms and Fortune 500 companies, before the U.S. Federal Trade Commission.


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Note : Your Quotation Request will be directed to Dbwave Technologies.
The DBLNA315002700A from Dbwave Technologies is a RF Amplifier with Frequency 15 to 27 GHz, Gain 33 dB, Gain Flatness 1.5 dB, Noise Figure 2.5 dB, P1dB 29 dBm. Tags: Low Noise Amplifier. More details for DBLNA315002700A can be seen below.
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Produced once more by his New York neighbour Arto Lindsay, Brazilian singer-songwriter and guitarist Cantuaria's latest album – launched with a concert at London's Barbican on Tuesday – returns to the laid-back, drifting samba-jazz with which he made his name.
For those yet to claim an aquaintance, Cantuaria is a class act whose gentle songs (in Portuguese) are set to magical soundscapes of considerable poetic appeal. Guests include US stars Bill Frisell and Brad Mehldau alongside the outstanding drummer Paulo Braga.
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[Temptations of the World] : manuscript fragment of a religious text
- Language
- Latin. In Latin.
- Imprint
- Northern Italy?, circa 1200
- Physical description
- 1 item (4 p.): vellum; 260 x 175 mm.
Available online
Special Collections
All items must be viewed on site
Request items at least 2 days before you visit to allow retrieval from off-site storage. You can request at most 5 items per day.
|Call number
|In-library use
In collection
Stanford University Libraries Special Collections, Manuscripts Division
The Manuscripts Division of the Department of Special Collections at Stanford University Library exists to arrange, describe, preserve, and make available documents of enduring historic value, both as intellectual items \n and as historical artifacts, to support the research needs of the undergraduates, graduate students, faculty and other scholars at Stanford University and beyond.
- Digital content
- 88 items
- Collection PURL
- http://purl.stanford.edu/sk373nx0013
More options
- Summary
- A fragment of an unidentified devotional text treating the dangers of worldly temptations occasioned to the believer in the Christian life by the vices of the world.
- Local subject
- 13th century CHR > Italy.
- Medieval and Renaissance studies > Italy > 13th century.
Bibliographic information
- Earliest possible date
- 1190
- Latest possible date
- 1210
- Note
- Rounded Carolingian-Gothic textata hand.
- Access
- Open for research; material must be requested at least 24 hours in advance of intended use.
- Citation
- Reported to: Bibliothèque Nationale pre-1600 ms. census.
- Source
- Purchased from the Rendells, 1979. Accession 1979-009.


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One of my favorite cars
- Posted May 22, 2010 by Trish Viewed 1214 times
- This is a migrated legacy post. Image resolution is low. Info
This photos was taken driving on a day with a friend I miss dearly…and his car. That day, even the mirror seemed beautiful to me..everything was beautiful when we were in love….
Even the reflections behind me…
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Heartbreaking Details Of How School Children Lost Their Lives While Using Wooden Bridge As Passage [See Graphic Photos]
This is really sad; May their souls rest in perfect peace… Amen, Read & see all the photos below…
Imagine how Children going to school just to get education using this wooden bridge as a passage and unfortunately the bridge fell down while carrying them which cause the children to lose their lives. May their souls rest in perfect peace… Amen
This is a big shame to African leaders, Especially to that Cameroonian President who has been in power for ages with little to show for it.
As shared by a facebook user: Emeka Onuigbo


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If You Use a Screen ReaderThis content is available through Read Online (Free) program, which relies on page scans. Since scans are not currently available to screen readers, please contact JSTOR User Support for access. We'll provide a PDF copy for your screen reader.
Nutrient Input to an Alpine Tundra: An Aeolian Insect Component
James Halfpenny and Michael Heffernan
The Southwestern Naturalist
Vol. 37, No. 3 (Sep., 1992), pp. 247-251
Published by: Southwestern Association of Naturalists
Stable URL: http://www.jstor.org/stable/3671865
Page Count: 5
Topics: Moths, Insect vectors, Alpine tundra, Nitrogen, Snow, Acid soils, Phosphorus, Potassium, Soil ecology, Insect ecology
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Large quantities of non-alpine insects are blown episodically onto some alpine tundras. These events may have return intervals as short as 3 years in Colorado. Windblown depositions of a moth (Loxstege cerareoles, Pyralidae) from one episodic event were analyzed to determine the possible influx of soluble nutrients to the alpine tundra. Ten chemicals were identified in or on the insect bodies. Significant external additions of soluble phosphorus and potassium occurred to the alpine, but additions of soluble nitrogen were probably not significant. Phosphorus additions may represent a relatively new input source emanating from contamination by fertilizers used on alfalfa crops on the Great Plains. Potassium inputs may originate in the soils of the Great Plains and may increase buffering capacity in the poorly buffered tundra soils of the Colorado Front Range.
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The Southwestern Naturalist © 1992 Southwestern Association of Naturalists


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Is Rooster's B & B incorrect or missing key business information? Update your Hotfrog listing today.
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Hotfrog SouthAfrica provides information regarding Rooster's B & B in Frankfort Free State. Rooster's B & B is located at 25 Kerk St, Frankfort Free State 9830 and provides Travel services. Contact them on 073 228 9085 or by visiting them on their website http://www.frankfortaccommodation.co.za.
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17A CHURCH STREET Frankfort Free State 9830
67 B JJ Hadebe Street Frankfort Free State 9830
326 West Main Street Frankfort Free State 9830
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The BulletBlocker NIJ IIIA Bulletproof 100% Lamb Leather Jacket is classically styled with a straight hem that will fit comfortably over any type of clothing. It has a standard, shirt-type collar with a full zippered front for easy wearing and offers a discrete yet lightweight NIJ IIIA bullet-resistant hidden liner. Its multi-pocketed design attributes to the functionality of this handsome coat. The exterior is constructed of smooth genuine lamb leather that will continue soften over time. It is a design that will never go out of style!Features and Benefits
* Level IIIA removable ballistic liner
* Heavy-duty brass zipper
* Two inside pockets
* Inside breast pocket
* Nylon lining with polyester fiberfill
* Easy care instructionsBallistics
* Removable Kevlar bullet resistant interior liner for cleaning and maintenance.
* Meets NIJ IIIA standards that will stop a 357 Magnum, 44 Magnum, 9mm, .45, hollow point ammunition and more.
* Provides identical ballistic protective coverage area as traditional law enforcement body armor.
Measure under arms and across shoulder blades
Measure from center back of neck, over the shoulder, down the
arm to wrist.
Measure around your waistline.
Updated Feb 07, 2017


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When I filter their 20,000-word articles I am left with two words I can possibly digest without getting acid reflux. To me they are useless. I haven't read their reviews for the past two years and my neurons have surprisingly been regenerating. For worthwhile reviews I read what you guys have to say.
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May-06-2013, 01:04 PM #1
Status :Rank : ModeratorJoin Date : Oct 12, 2009Location : Wheatfield, IndianaPosts : 18,762Threads : 152Last Online : Nov-22-2016 @ 01:42 PM
Seating preference for the Tailgate
I got off the phone today with The pirates ticket office and they said we could have the seats we had last year in the upper grandstands behind Home plate ( sections 316-317) but the Prices have climbed from $16 to $21. Sections 322-323 are available for $15. Let's decide on this by Wednesday night and everybody can start paying by clicking the donation button for Pittsburgh Sports Forum. I'd like to order the tickets by Thursday, Friday at the latest. When you pay, just leave a notice saying "Tickets" so it don't get confused with regular donations to the board.
SteelreignPittsburgh Sports Forum: Member Driven and no ads
May-06-2013, 03:19 PM #2Status :Rank : 1st Ballot Hall Of FamerJoin Date : Oct 12, 2009Location : York, SC, United StatesPosts : 5,609Threads : 213Last Online : Feb-16-2017 @ 04:45 PM
Re: Seating preference for the Tailgate
Makes no difference to me. $5 bucks won't kill me. Whichever seats are lower I suppose.
May-06-2013, 04:37 PM #3Status :Rank : 1st Ballot Hall Of FamerJoin Date : Oct 11, 2009Location : Avalon, PAPosts : 6,607Threads : 24Last Online : Aug-10-2016 @ 03:02 PM
Re: Seating preference for the Tailgate
I know this will be very little to no help, but I'm happy to go wherever. Just say the word and I'll send the dosh. Cheers, mate!'I want rustlers, cut throats, murderers, bounty hunters, desperados, mugs, pugs, thugs, nitwits, halfwits, dimwits, vipers, snipers, con men, Indian agents, Mexican bandits, muggers, buggerers, bushwhackers, hornswogglers, horse thieves, bull dykes, train robbers, bank robbers, ***-kickers, ****-kickers and Methodists.'
May-08-2013, 05:02 AM #4Status :Rank : Pro Bench WarmerJoin Date : Oct 23, 2009Location : Pirates fan trapped 11 CTA stops north of Wrigley FieldPosts : 1,227Threads : 26Last Online : Jun-28-2016 @ 06:39 PM
Re: Seating preference for the Tailgate
I'm only able to post this to BD just now [weds 4am] -I've put a poll up there that ends on Friday at 9 am EDT - izzat okay?
Also, you need to give us your PayPal info, amigo - we want to make sure you get paid tout suite!
Last edited by cocktailsfor2; May-08-2013 at 05:37 AM.Free your *** and your mind will follow.
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Aptos is located in Santa Cruz county and has a population of 9,396.
LVN schools in Aptos charged students an average tuition of $728.00 if they were California residents, and $6,160.00 if they were non-residents, during the 2009 - 2010 school year.
Books and supplies for lvn schools in Aptos cost an average of $1,638.00. There is one lvn college in Aptos. In the 2008 - 2009 school year, reportedly 55 students completed lvn programs in Aptos.
|Average Salary
|Number Employed in City
|Licensed Practical and Licensed Vocational Nurses


text: Site Gallery Looks To Next Level With Support From Legal Specialists Sheffield Gallery Appoints Lawyers To Aid Capital Development Programme 13.03.2015 Site Gallery, Sheffield's leading contemporary art gallery, has appointed real estate and charity law specialists at Irwin Mitchell to help it as it takes the next step forward in its development. The legal advisers based at the national law firm's Sheffield office will provide support during the gallery's capital development bid, based around plans for a substantial redevelopment of the gallery to extend its spaces and create more areas for exhibitions and teaching. This will include a second stage application for Arts Council England funding and a pre-construction period. Home to an array of exhibitions, commissions, events, talks and education projects, Site Gallery supports artists specialising in moving image, new media and performance, working in partnership with local, regional and international collaborators to nurture artistic talent and invest in artists at critical stages of their careers. Site Gallery's recent alumni won the most prestigious awards in the art-world; The Turner Prize, the Venice Silver Lion and the Frieze Emdash Award. Judith Harry, Executive Director of Site Gallery, based on Sheffield's Brown Street, said: "This project will secure a brighter future for Site Gallery, and will greatly increase resource for artistic and audience focussed activity in Sheffield. The gallery was last refurbished 16 years ago, and this investment will allow us to greatly improve our audiences' experience and make a more competitive offer to artists." Irwin Mitchell's team which will advise Site Gallery consists of Construction partner Julie Morrissy, Real Estate experts Wendy Greenwood and Graham Walker, as well as Laurence Gavin, a Partner who specialises in advising organisations in regulated sectors including charities. Expert OpinionSite Gallery is a core part of Sheffield's cultural offering and has a huge reputation both locally and further afield. "Being based in Sheffield, we are delighted to offer our support to such an important asset to the city and hope to help the gallery move to the next level in terms of its development – creating more opportunities for high quality exhibitions and projects for many years to come." Julie Morrissy, Partner Key contact Julie Morrissy Partner +44 (0)791 867 1665 Email Julie Tags Construction And Infrastructure Julie Morrissy Sheffield Related articles 22.02.2017Two-Thirds Of Leeds Businesses Hit By IT Hacks In 2016, Study Shows 20.02.2017Financial Conduct Authority And Prudential Regulation Authority Publish Decision Making Changes 15.02.2017Cocoon Aims To Secure £2.5m For Latest Expansion Drive 14.02.2017Serious Fraud Office - The Big Funding Debate 14.02.2017Inflation Rises As UK Feels Effect Of Weak Pound Post-Brexit Vote


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Bashshur ZF, Schakal A, Hamam RN, El Haibi CP, Jaafar RF, Noureddin BN. Intravitreal Bevacizumab vs Verteporfin Photodynamic Therapy for Neovascular Age-Related Macular Degeneration. Arch Ophthalmol. 2007;125(10):1357-1361. doi:10.1001/archopht.125.10.1357
© 2017
To compare verteporfin photodynamic therapy (PDT) with intravitreal bevacizumab for management of choroidal neovascularization (CNV) associated with age-related macular degeneration.
Patients with predominantly classic CNV were prospectively randomized to receive standard PDT or intravitreal bevacizumab injections (2.5 mg). Best-corrected visual acuity (BCVA) measured by Snellen charts, central retinal thickness by optical coherence tomography, and greatest linear dimension of the CNV by fluorescein angiography were compared between the groups at baseline and at 3 and 6 months. Main outcome measures were stability or improvement in BCVA, decrease in central retinal thickness, and stability in greatest linear dimension.
Mean baseline BCVA, central retinal thickness, and greatest linear dimension were not statistically different between the bevacizumab (n = 32) and PDT (n = 30) groups. Mean central retinal thickness was significantly better at 3 and 6 months in the bevacizumab group vs the PDT group (P = .04 and P = .002, respectively). At 3 months, mean BCVA and greatest linear dimension were not significantly different between the 2 groups. At 6 months, mean BCVA and greatest linear dimension were significantly better in the bevacizumab group (P < .001 and P = .02, respectively).
During 6 months, intravitreal bevacizumab was superior to PDT in controlling predominantly classic CNV in age-related macular degeneration. Additional randomized clinical trials are necessary to determine if this benefit will remain with longer follow-up.
Age-related macular degeneration (AMD) is the leading cause of irreversible loss of central vision in people older than 50 years in industrialized countries.1 The less common neovascular form, choroidal neovascularization (CNV), causes 80% to 90% of cases with severe vision loss in AMD.2 Choroidal neovascularization is at least partly mediated by vascular endothelial growth factor (VEGF).3- 5
Photodynamic therapy (PDT) with verteporfin was shown to be effective in decreasing the probability of moderate and severe vision loss from predominantly classic subfoveal CNV.6- 8 Although PDT allows selective photothrombosis of the CNV, loss of vision continues mostly in the first year of treatment and to a lesser extent during the second and third years.8
In December 2004, the US Food and Drug Administration approved intravitreal pegaptanib sodium for management of CNV. It is an anti-VEGF aptamer injected intravitreally and binds isoform 165 of VEGF. Pegaptanib sodium was shown to reduce the risk of vision loss from CNV, while vision gain was reported in only 6% at 12 months.9,10 Another anti-VEGF agent, ranibizumab, is an antibody fragment targeting all isoforms of VEGF. It was reported to decrease the chance for a decrease in visual acuity and improve visual acuity at 12 months.11 It was also found to be superior to PDT in changing mean visual acuity, with a mean 8- to 11-letter gain seen in the patients treated with ranibizumab vs a mean loss of 9.5 letters in patients treated with PDT.12
Bevacizumab is a full-length humanized monoclonal antibody of similar molecular lineage as ranibizumab and binds all isoforms of VEGF. It was developed for cancer treatment,13 but intravitreal bevacizumab seems to be effective in the treatment of neovascular AMD.14- 17 Because of its availability and low cost, bevacizumab is favored in many countries for treatment of neovascular diseases of the eye.18 Studies dealing with bevacizumab and AMD are small nonrandomized pilot studies, and safety and efficacy reported in the literature do not exceed 3 months of follow-up. Moreover, it is unknown whether intravitreal bevacizumab is as efficacious as PDT in the management of neovascular AMD. This study is a randomized, prospective, interventional case series comparing, during a period of 6 months, intravitreal bevacizumab with PDT for the management of predominantly classic CNV in AMD.
The study was approved by the institutional review board at the American University of Beirut Medical Center and was in adherence to the tenets of the Declaration of Helsinki. Starting September 2005, eyes with predominantly classic CNV that met the eligibility criteria summarized in Table 1 were enrolled in our study. Patients were randomized into the PDT or bevacizumab groups (1:1 ratio). Power calculation indicated that a sample size of 30 in each group was necessary to obtain statistical significance with 80% power and within a 95% confidence interval (α = 0.05). The procedure and treatment options were explained thoroughly to patients who then signed a study consent form. Patients receiving intravitreal bevacizumab were informed of the off-label use of the medication.
Baseline workup included best-corrected visual acuity (BCVA) using Snellen acuity charts, slitlamp examination of the anterior segment, dilated fundus examination, fluorescein angiography, and optical coherence tomography (OCT). The greatest linear dimension of the CNV was determined using fluorescein angiography and the incorporated measuring software (ImageNet 2000; Topcon, Tokyo, Japan). One millimeter central retinal thickness was measured using OCT (Stratus OCT, Carl Zeiss Meditec, Dublin, California). Macular retinal mapping was created from 6 consecutive slow diagonal 6-mm scans that intersected at the fovea. Retinal thickness, the distance between the vitreoretinal interface and the anterior surface of the retinal pigment epithelium, was measured automatically by the OCT software. Central retinal thickness and greatest linear dimension measurements were interpreted and recorded by an independent observer who was masked to the type of treatment.
Patients randomized into the PDT group were treated with PDT using verteporfin (Visudyne; Novartis Ophthalmics, Basel, Switzerland). A 30-mL solution containing 6 mg of verteporfin per square meter of body surface area was infused for 10 minutes followed by activation with a 689-nm diode laser at an irradiance of 600 mW/cm2 5 minutes later for 83 seconds producing a fluence of 50 J/m2. Treatment was applied to a spot size 1000 μm greater than the greatest linear dimension. Best-corrected visual acuity, slitlamp examination of the anterior segment, dilated fundus examination, fluorescein angiography, and OCT were performed at 3- and 6-month follow-up visits. Photodynamic therapy was repeated if leakage from CNV was present on fluorescein angiography.
Bevacizumab (Avastin, Genentech, San Francisco, California) was prepared by the hospital pharmacy into 1-mL tuberculin syringes and stored at 2°C to 8°C based on protocols described in previous studies.17 Eyes randomized to receive intravitreal bevacizumab were prepared with povidone iodine, 5%, solution and anesthetized with subconjunctival lidocaine, 2%. Using a 30-gauge needle, 2.5 mg of bevacizumab was injected intravitreally through the pars plana 3.5 mm from the limbus. Paracentesis was performed 20 minutes after the injection if intraocular pressure was greater than 25 mm Hg or if the optic nerve head was not adequately perfused. Patients unpatched the eye the next day and applied topical ciprofloxacin (Ciloxan; Alcon, Puurs, Belgium) 3 times a day for 3 days. Patients were examined at 1 week after an injection and then every month for 6 months. At each visit, BCVA was measured and slitlamp examination of the anterior segment and dilated fundus examination were performed. Optical coherence tomography and fluorescein angiography were repeated every month and every 3 months, respectively.
All patients in the bevacizumab group had blood pressure measurements at every visit. Complete blood count and urinary analysis were taken at baseline and 1 week after any injection. Patients were observed for any systemic thromboembolic events or ocular complications.
The induction phase of bevacizumab treatment started with the first injection and spanned 1 to 2 months depending on the number of injections the patient required. The need for retreatment after the first injection was based on the presence of subretinal fluid or cystic maculopathy as determined by OCT. As such, if there was total resolution of subretinal fluid and cystic maculopathy on OCT (ie, dry lesion) 1 month after the first injection, then the patient was followed up monthly. If there was persistent subretinal fluid or cystic maculopathy, then a second injection was given, and if needed, a third injection was given 1 month after the second. No more than 3 consecutive injections were given in the induction phase even if the lesion was not totally dry.
After the induction phase, patients were observed with monthly OCT. We assumed that determining worsening subretinal fluid and especially cystic maculopathy on OCT images could be somewhat subjective in a lesion that was not previously dry. We considered that an increase in central retinal thickness measured by OCT would more objectively reflect an increase in subretinal fluid and cystic maculopathy in such lesions. Therefore, reinjection during follow-up was based on the following criteria: (1) recurrence of subretinal fluid or cystic maculopathy on OCT in a previously dry lesion; (2) increase in central retinal thickness by more than 100 μm, especially for lesions that were not totally dry; (3) a new area of classic CNV; (4) new hemorrhages; or (5) decrease of 2 or more lines in highest recorded BCVA associated with increased leakage on fluorescein angiography or OCT. Photodynamic therapy was considered if the treating ophthalmologist judged that bevacizumab treatment was not working of the patient.
Main outcome measures were stability or improvement in BCVA, decrease in central retinal thickness, and stability in greatest linear dimension. Snellen acuities were converted to logarithm of the minimum angle of resolution units to facilitate statistical analysis. Decreased visual acuity was defined as a loss of more than 3 lines of BCVA from baseline. Improved visual acuity was defined as an increase of 3 or more lines of BCVA from baseline. The t and χ2 tests were used for statistical analysis. The level of statistical significance was set at P < .05 with a 95% confidence interval.
A total of 64 patients, equally divided between the 2 groups, were recruited for this study. Two patients in the PDT group were lost to follow-up shortly after the first treatment and were not included. By the end of the study, 32 patients in the bevacizumab group and 30 patients in the PDT group completed 6 months of follow-up. The mean age was 75.4 and 74.6 years in the bevacizumab and PDT groups, respectively (P = .67). There were 18 women and 14 men in the bevacizumab group, while there were 13 women and 17 men in the PDT group.
Patients in both groups had no systemic or ocular complications. There was no remarkable change in blood pressure in the bevacizumab group at any follow-up visit. Similarly, there was no change in the urinary analysis or complete blood count after any bevacizumab injection.
The PDT group received a mean 2.3 treatments during 6 months vs a mean 2.4 injections in the bevacizumab group (P = .4). In the PDT group, 18 eyes (60.0%) required 3 treatments, 10 eyes (33.3%) required 2 treatments, and 2 eyes (6.7%) received 1 treatment during the 6 months. Patients in the bevacizumab group received a mean 1.6 injections in the induction phase and a mean 0.8 injections during follow-up. In the induction phase, 6 eyes (18.75%) received 3 consecutive injections, 6 eyes (18.75%) received 2 consecutive injections, and 20 eyes (62.5%) received 1 injection. The mean time between the last injection in the induction phase and the need for retreatment was 3.2 months. During follow-up, 4 eyes (12.5%) received 2 injections, 20 eyes (62.5%) received 1 injection, and 8 eyes (25.0%) did not require any injections. During 6 months, 18 of 32 (56.3%) eyes required fewer than 3 bevacizumab injections.
Mean baseline BCVA was 20/119 in the bevacizumab group and 20/108 in the PDT group (P = .50). At 3 months, mean BCVA was 20/89 in the bevacizumab group and 20/118 in the PDT group (P = .09). At 6 months, mean BCVA had improved to 20/68 in the bevacizumab group, while mean BCVA was 20/143 in the PDT group (P < .001). By 6 months, 6 of 32 (18.8%) eyes in the bevacizumab group had 20/40 or better BCVA, while no PDT eyes achieved this visual acuity (P = .02). Five of 30 (16.7%) eyes in the PDT group ended with a BCVA worse than 20/200, while no eyes in the bevacizumab group did (P = .02). Table 2 summarizes the change in mean BCVA over time and Table 3 presents the distribution of visual acuity at baseline and 6 months for both groups. At the conclusion of the study, 32 of 32 eyes in the bevacizumab group and 22 of 30 (73.3%) eyes in the PDT group avoided losing more than 3 lines of BCVA (P = .002), while 16 eyes (50.0%) in the bevacizumab group had improvement in BCVA vs 5 (16.7%) in the PDT group (P = .007).
Baseline central retinal thickness was 352 μm and 354 μm in the bevacizumab and PDT groups, respectively (P = .92). At 3 months, central retinal thickness decreased to 262 μm in the bevacizumab group and 300 μm in the PDT group (P = .04). At 6 months, central retinal thickness decreased further to 241 μm in the bevacizumab group and 292 μm in the PDT group (P = .002). Table 4 presents the change in mean central retinal thickness of both groups at baseline and at 3 and 6 months. At 3 months, 22 of 32 (68.8%) eyes in the bevacizumab group had a dry lesion vs 8 of 30 (26.7%) eyes in the PDT group (P = .001). At 6 months, 23 eyes (71.9%) in the bevacizumab group and 15 eyes (50.0%) in the PDT groups had dry lesions (P = .12).
The mean baseline greatest linear dimension was 2801 μm in the bevacizumab group and 2366 μm in the PDT group (P = .79). By 3 months, the mean greatest linear dimension was 2665 and 2871 μm in the bevacizumab and PDT groups, respectively (P = .46). At 6 months, mean greatest linear dimension had improved to 2593 μm in the bevacizumab group, while mean greatest linear dimension in the PDT group was 3377 μm (P = .02).
The first evidence of recurrence in the bevacizumab group was subretinal fluid or intraretinal cystic changes on OCT but this was considerably less than baseline. Despite this recurrence on OCT, late leakage on fluorescein angiography was generally absent or sometimes much milder than baseline.
The main aim of this study was to compare intravitreal bevacizumab with PDT for management of predominantly classic CNV in neovascular AMD. Predominantly classic CNV cases were selected in this study because it was more meaningful to compare intravitreal bevacizumab to PDT in the management of the lesion subtype that is most responsive to PDT. Best-corrected visual acuity, central retinal thickness, and greatest linear dimension were used to gauge disease control. During 6 months, intravitreal bevacizumab was superior to PDT in controlling the CNV. Generally, the difference was more significant after 6 months than 3 months. It seems that anti-VEGF therapy causes rapid resolution of edema and subretinal fluid but does not completely eradicate the CNV lesion, which probably lays dormant as long as VEGF is inhibited. Once well established, CNV may not be eliminated with suppression of VEGF alone.19 This may explain why we did not observe a rapid reduction in greatest linear dimension with bevacizumab vs PDT.
Photodynamic therapy can cause temporary occlusion of the choriocapillaris in the area of treatment, increased release of VEGF, early increase in subretinal fluid, and possible damage to the retinal pigment epithelium.20- 25 Although PDT induces closure of the CNV soon after treatment, it does not address the state of increased VEGF in neovascular AMD, which allows reproliferation of the CNV.25- 27 Therefore, repeated treatments may lead to cumulative damage to the retina and choriocapillaris, which eventually may affect visual acuity. Recent studies have shown that intravitreal bevacizumab does not seem to be toxic to the retina or retinal pigment epithelium.28- 31 Bevacizumab may deprive the CNV of VEGF, which causes decreased vascular permeability and inhibits progression of immature vessels without having a direct effect on surrounding tissue in the short term.32,33 It is not possible from this study to predict if prolonged VEGF inhibition will eventually cause damage to the retina or the normal retinal and choroidal vessels.
Patients in the bevacizumab group had monthly follow-up with OCT to determine the need for further treatment. Recurrence was noted on OCT before any changes occurred on fluorescein angiography. There are some small, nonrandomized studies that incorporated OCT with PDT treatment.34- 37 However, our purpose was to compare intravitreal bevacizumab with standard-care PDT for management of predominantly classic CNV. This is why treatment and follow-up in the PDT group were based on recommendations from major studies, most notably the Treatment of Age-Related Macular Degeneration With Photodynamic Therapy studies.6- 8
A second aim of this study was to examine the efficacy of intermittent OCT-guided bevacizumab injections. This study showed that during the induction phase, the CNV was dry in 81.3% of eyes after the first or second injection (mean 1.6 injections), and this treatment benefit seemed to last for a mean 3.2 months. Reinjections were done when there was an early recurrence on OCT, making it unnecessary to resort to multiple consecutive injections once the lesion was dry. As a result, 87.5% of eyes required fewer than 2 injections (mean, 0.8) during follow-up. Minimizing the number of injections may reduce potential ocular or systemic adverse effects of prolonged and constant VEGF inhibition.
The ability of bevacizumab to cross the retina has been the subject of some speculation. Based on previous animal studies, it was assumed that the bevacizumab molecule was too large to cross all the retinal layers to reach the subretinal space.38 However, a recent study showed that bevacizumab crossed into the subretinal space in the rabbit retina.30 Moreover, clinical data from previous studies16- 19 and this study seem to support the fact that intravitreal bevacizumab can cause regression of CNV and reduction in vascular permeability.
An intravitreal dose of 2.5 mg (0.25 g/L) of bevacizumab was well tolerated and no postinjection inflammatory response was noted. This is compared with ranibizumab, which has a maximal tolerated dose of 0.5 mg (0.1 g/L).39 One possibility is that ranibizumab can be more immunogenic than bevacizumab. As bevacizumab is a full-length antibody, the Fc fragment can interact with immune effector cells, but this may actually cause an inhibitory effect.40 Nevertheless, the dose of intravitreal bevacizumab used in this study was twice that of other studies.18,19 The purpose for such a higher dose was to allow a greater concentration of bevacizumab to penetrate the retina. It was also hoped that the longer half-life of bevacizumab41 and larger dose may allow a more prolonged inhibition of VEGF and decrease the frequency of reinjections.
There are several potential ocular and systemic complications related to intravitreal bevacizumab injections. Systemic adverse effects from intravenous use of bevacizumab include increased risk of thromboembolic events, hypertension, epistaxis, hemoptysis, proteinuria, delayed wound healing, and impaired reproductive function.42 The dose in intravitreal injections is several magnitudes smaller than the systemic dose, and direct intraocular use may reduce systemic adverse effects and allow direct targeting of the CNV. However, there is the potential for acute vision loss, ocular vascular occlusions, retinal pigment epithelial tears, subretinal hemorrhage, ocular toxicity, and inflammation.43 There are also risks that can be encountered from any kind of intravitreal injection, including endophthalmitis, retinal detachment, vitreous hemorrhage, corneal abrasions, and lens injury.43 In this study, no ocular or systemic adverse effects were noted after several injections during a period of 6 months.
In conclusion, intravitreal bevacizumab can be used to manage predominantly classic CNV in AMD. It may even be superior to PDT in the short term. Another potential benefit for intravitreal bevacizumab for treatment of AMD is the relatively low cost. In this study, the mean cost of verteporfin for a period of 6 months was $3450 vs $160 for bevacizumab. As far as we are aware, this is the only randomized, prospective controlled case series comparing PDT with intravitreal bevacizumab for the management of neovascular AMD. However, this study has many shortcomings. Most notable are the limited follow-up, small number of patients, and nonstandard refractions. Additional, larger, randomized clinical trials are necessary to determine the efficacy and safety of intravitreal bevacizumab in the long-term treatment of neovascular AMD. Issues of the most appropriate dose and treatment interval need to be addressed.
Correspondence: Ziad F. Bashshur, MD, American University of Beirut Medical Center, PO Box 11-0236/B11, Beirut, Lebanon (firstname.lastname@example.com).
Submitted for Publication: October 30, 2006; final revision received February 15, 2007; accepted March 9, 2007.
Author Contributions: The principal investigator Dr Bashshur had full access to all the data in the study and takes responsibility for the integrity of the data and the accuracy of the data analysis.
Financial Disclosure: None reported.


text:
Andrew Parikh
Business Development
Andrew is a financial and operations analyst with a diverse background in biochemical research, healthcare, hospitality management and database architecture. At Tilray, he focuses on building strategic partnerships and developing creative business solutions.
Revenue Analyst at Leafly. Leafly is the world's largest online cannabis information resource. Millions of patients and consumers use Leafly to explore cannabis strains & products, find dispensaries, retail stores, and doctors, and access cannabis news, research, and culture. Andrew was responsible for collecting and analyzing sales revenue and providing recommendations to senior management on emerging cannabis markets.
Duty Manager at Fairmont Hotels & Resorts. Fairmont Hotels & Resorts enjoys a worldwide reputation for accommodation excellence, with a global portfolio that includes historic icons, elegant resorts and modern city-center properties. While at Fairmont, Andrew was repeatedly recognized for outstanding performance and directly contributed to four years of record-setting room revenue.
University of Washington: BA


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Get a Widget
There's more information needed before this can be even roughly estimated. "7 ply" works out to quadruple-wall, which I've only seen in some agricultural totes.
Burst is a function not just of number of "plys" used, but of paper thickness, recycled vs. virgin content, and corrugator consistency. Size of the box has little impact on burst strength, which is why many in the industry specify by either ECT or top-to-bottom compression strength now (as these measures take box size into account).
Oct 24, 2013 - 02:13 PM


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OP, this man is not respecting you as a mother. I've been a fifo partner and a mother with a new born for a short time (with DP being away for 4 weeks at a tim) and yes they are working hard away, but you are also the sole carer for the children when they are away. 24/7 no nights off, plus you have to handle everything on the home front all alone. No one to help you carry the groceries in, no one to help when the kids are sick and so are you.
Working, as well as having young children while being a FIFO widow is bloody tough. If my partner had continued fifo, or goes back to it, i won't return to part time work while my DS is small.
That email was just disgusting, i would not be sticking around to put up with that.
You ARE working, you are raising the children. If he earn's plenty of money to keep the family afloat, there is no need for you to work while your youngest is small.


text: I found this on a church web site. Holy Communion (or the Lord's Supper) is a mystery too deep for words. Its meaning will vary for each of us and from one time to another. But three essential meanings are caught up in this proclamation in our Communion service: "Christ has died; Christ is risen; Christ will come again" We offer Holy Communion at all of our worship services on the first Sunday of every month. I don't believe that Communion is a mystery. I believe the meaning is very clear.


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Let us know when your receive great advice so we can thank our lawyers and point others with similar questions in the right direction.Got it!
i was not ordered to do sex offender treatment because she lied about her age.
is it legal for the courts to dispose of my sentencing hearing and my trial?
I don't know what you mean by "throw away your sentencing hearing." A hearing isn't a thing that you can "throw away." You certainly shouldn't blow off your hearing, if that's what you mean. If you're going through a criminal prosecution, you should consult with an attorney, and do what they say.
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A hearing is an event, not a physical object - so it cannot be thrown away or "disposed." If you were convicted, then you were also sentenced, and the court will have a record of that sentencing hearing. You may need to go to the county courthouse where you were convicted in order to get the right records.
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Bryan Burk is a sought-after international commodity trader, an options expert and analyst. He spent nearly 35 years on Wall Street, including two decades on the trading desk of Phillip Brothers, which became Salomon Brothers and ultimately part of Citigroup. Andy went on to work with a number of banks, hedge funds and traders in the world of commodities.Bryan Burk Technical Direector
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text: Hi,I am trying to understand how WME/WMM works in MadWiFi. What I am interested in finding out is when and how are different ACs used based on traffic. While goingthrough the code, I saw that different hw queues are set up for different access categories like WME_AC_(BK/BE/VI/VO) and the corresponding parameters for AIFS and CWmin and CWmax are setup properly. In the life cycle of a packet arriving from upper layers,ieee80211_hardstart calls ieee80211_classify to calculate the priority level and hence the AC for the traffic type. What I found surprising, or rather discomforting is that ieee80211_classify looks atonly VLAN id and/or IP TOS to determine the AC class. Now from what I observedfrom traffic traces and also read on the Internet that IP TOS field is almost never used. All voice (Gtalk and Skype) and video streaming traffic data arrives from the applicationswith the IP TOS field as 0. So the big question troubling me is that when (if ever) is data actually sent using a different AC class other than the default WME_AC_BE? What am I missing here (assuming I am not using VLANs)? Does madwifi never actually use different ACs. Should there be a more intelligent classification function or is this the responsibility of the applications. Is there some other way by which the applications communicate to the MAC that the data is high priority?I would really appreciate any help in understanding the working of WME capabilities.Thanks in advanceAshish


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Join Serene Education Academy for expert forex strategies and training courses in Wales, UK. Get forex seminar and understand basics of trading and forex charts become a pro!
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For nearly 60 years, The Arc of Anchorage has been a family-focused, grassroots organization that provides a full array of disability services for Alaskans with intellectual and developmental disabilities. The Alaskans we serve and their families are free to choose disability services that best meet their needs. We recognize each person we serve has specific dreams, ambitions and interests, as well as aptitudes and abilities apart from the disability he/she experiences. Our services are individually tailored to meet the needs and goals of each person we serve. The Arc is also the leading expert resource for the media, business and government about people with intellectual and developmental disabilities, including their real abilities, their needs, and the barriers and obstacles they face in their quest to be fully included in society.
The Mental Health Treatment Clinician is responsible for providing therapeutic services and quality assurance to Mental Health, Substance Abuse and other services, which comprise individuals who experience severe emotional disturbance and other co-occurring disorders. The Clinician may provide some clinical consultation and training. This position works under close supervision of the Director ...read more
Off of Northern Lights Boulevard between UAA Drive and Bragaw.


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Assorted Files - Set of 5 2nd Cut Assorted Pack of Round, Flat, 3-Square, Half Round Engineers Files
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Heat Shrink Tubing Dia: 4.8-12.7mm
Price: £8.20 (Ex. VAT)
Price: £27.50 (Ex. VAT)


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Boost your upper body workout with SKINS range of men's compression tops. SKINS long and short-sleeve tops wrap and support sections of your arms, shoulders and core to pump oxygen into key upper body muscle groups. What that means for athletes that depend on a strong top half is improved core body control and power, reduced injury risk, plus less muscle pain after exercise.
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I WELL remember my first visit to the Fennells in North Oxford: our tall and gently humorous host dispensing enthusiastic hospitality in a setting presided over by his wife Marina. It was her unmistakably Russian warmth which made their welcome so special. And, for me, the encounter was to become very important.
It was not Cambridge (where in 1937 he went to read for the Modern Languages Tripos) that taught John Fennell Russian. He taught himself; indeed, his command of the Russian language was such that native speakers began to envy him his tournure de phrase. He was the obvious choice for the job of General Alexander's interpreter; and, after the war, for a Cambridge lectureship in the Department of Slavonic Studies. This post became the first step in a brilliant academic career.
But his fascination with Russia went much deeper than academic endeavour. During the war, in Cairo, he was received into the Orthodox Church. At Fennell's funeral, Bishop Kallistos said that he loved Orthodox Russia. This was undoubtably true in the sense that to John Orthodoxy and Russia were inseparable. Of course, he was aware of, and disliked, the darker sides of Russian history, and his abhorrence of the Soviet regime was obvious. But through the filter of Orthodoxy he was able to glimpse what was in Russia great and good. The choice of his Russian friends - a small and outstanding circle - bears witness to this.
The crowning of his career came in 1967 with the appointment to the Chair of Russian at Oxford. With this went two great fringe benefits, so to speak. One was a fellowship of New College, arguably the most splendid of all Oxbridge colleges. The other was the typically Oxonian vagueness of his academic remit: his was the chair of Russian - not Russian literature, or Russian history. In other words, he was given the luxury of choice within the bounds of, at the one end, literary analysis, and at the other, historical synthesis. Fennell, the acclaimed textologist and 'interpreter of the complexities of the Russian language', elected to concentrate on history.
It is interesting and, I think, significant, that in his historical pursuits he should have moved backwards through time. Having begun with Ivan Grozny and 16th- century Muscovy on the brink of imperial expansion, he proceeded to write The Emergence of Moscow 1304-1359 (1968), and then The Crisis of Medieval Russia 1200-1304 (1983). His personal commitment to Orthodoxy was paralleled by a relentless pursuit of the roots of Russia's statehood. It was a composite road towards understanding the essence of Russia. As chance would have it, his wife's family tree (she was born Lopukhina) effectively encapsulated Russia's history - an added short cut in that pursuit.
The hallmark of Fennell's output was a rigorous, almost ruthless reliance on primary sources. As a result of this discipline his analysis was uncompromising, brave, always original, and at times controversial. In his Crisis of Medieval Russia, for example, he expressed views on Alexander Nevsky which were very different from the standard Soviet eulogies. In spite of this, Fennell's book was translated into Russian and published in the Soviet Union just before its demise. This surely must be the ultimate accolade to his scholarship - and also a happy signal of changing Russian attitudes.
Fennell was fascinated by the phenomenon of tiny Lithuania's expansion into vast Rus', and he viewed it from the point of view of Moscow. My own work in the same subject was Lituanocentric. He very generously took an interest in my tentative results, enjoying, I suspect, our opposing perspectives. Soon swords were replaced by gin-and-tonics, and hands were extended across the Dnepr. I found myself safe under his professional wing, yet exposed to his gentle pressure for results. There was little choice but to put pen to paper. And ever after, for some 10 years in fact, I worked happily within the range of his discreet but persistent cajoling for more. Looking back, I understand now what a splendid teacher and magister Fennell must have been. He was prepared to extend his influence beyond the formal boundaries of academe, and to take a risky interest in the likes of me - independent aspirants from other fields. He was a Good Samaritan of scholarship.
And not only scholarship. A great deal of his time was channelled into the work of the Samaritans, and also into Sir Michael Sobell House in Oxford. Only when John Fennell died did the patients discover that the gentle and self-effacing regular helper was a professor of world renown. This, more than anything else, sums up the man.
Fennell has left an unfinished, but well-advanced, history of the Russian church. I was privileged to see some of the drafts and I feel that this might have become his crowning opus. This work, together with his unstinting support for 'The Voice of Orthodoxy', a radio station transmitting religious programmes to the peoples of the former Soviet Union, was I think intended as a special gift to his Church, from a faithful member. In the interest of scholarship, and of ecumenism, his text must be edited and published.Reuse content


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Gorgeous Jeannie!
Hi Sam. I feel lucky now that I live so close! Hope it all works really quickly for you. Can't believe it's cheaper to come down here than stay in QLD.
We were out of pocket around that much including specialist fees. Good value!
Gorgeous Jeannie!
Hi Sam. I feel lucky now that I live so close! Hope it all works really quickly for you. Can't believe it's cheaper to come down here than stay in QLD.
We were out of pocket around that much including specialist fees. Good value!
Last edited by hwaterhouse; 25-06-2014 at 15:26.
@jeannie he is so gorgeous!
@Sam90 it depends on how you are going to pay. If you do the Medicare safety net claim back thing it will be close to $4600 you will need to pay on the day. You get an interim receipt and then on the day of transfer you will receive an itemised receipt that you send to Medicare and they will refund you directly. If you haven't reached the threshold for the year it's about 1400-1600 you will be out of pocket (so the refund check will be around $3k).
But if you are doing it the other way, I think you pay the $1400 out of pocket directly to westmead and fill in a form for Medicare which pays westmead directly. But it means you are out of pocket the exact same amount for every cycle you do in one year.
I did 4 ivf cycles last year, the first one I was out of pocket 1400 but the subsequent ones it was only 490 (and that's because I paid an extra 200 for lucrin). I think the prices have gone up slightly this year but not much.
How are you going to handle all the scans and blood tests during the cycle? Normally once you start fsh you go in for a bt on day 6 then you have bt and ultrasounds every cpl of days till you're ready for epu.
Afm- I had a bad day today. I woke up feeling quite ill. Almost like I was hungover! I got up, took my meds and had a small brekkie then went back to bed. Unfortunately we had to drive back up to Auckland today so I had to get up eventually! I'm trying not to read to much into it, I don't have sore boobs or anything and had more symptoms before and thought I was pregnant but wasn't! I am 5dp5dt so will probably start poas on Friday.
Are there any doctors in Westmead Fertility that can collect only one or two eggs? I have a really low ovarian reserve. Thanks
wow I just wanted to thank you all for your responses and for being so welcoming! I am now super excited to be starting my journey and wish the 12th July was here NOW so I could get the ball rolling and meet with Dr Fong!!! lol @bel2466 I will have together my husband to start taking menevit...thanks for the tip @Ever1013 congratulations! 30 weeks, along...not long now and you'll have a gorgeous bub that's amazing! Good Luck x
I feel so much better now that I have heard such nice things about our FS! @Zobear @sarahf @mumnetqn @belle2466 , it's so nice to hear you have all had great experiences with Dr Fong! She sound a lovely so am looking forward to meeting her.
@mrsjaguar and @bel2466 Congratulations! Can definitely see the lines! yay!!!
@Chiefsgirl I have my fingers and toes crossed for you!
@jeannie1 your little boy is gorgeous!!!
@Sam90 Good luck with your journey...I'm new to WFC too so can't offer you any advice but fingers crossed for you! I have my appointment in the 12th also with Dr Fong so am super excited. I'm travelling from Bathurst so not as far as you. Where in qld are you from?
Hope ps I haven't missed anyone! I'm still getting used to the site etc!!!
Hope you are all well!
Lorna (Mummy2Harrison) xx
bel2466 (26-06-2014),Chiefsgirl (26-06-2014),hwaterhouse (26-06-2014)
@banshee the FS who do egg collection vary as to what day you go in. You don't necessarily get your FS for epu.
That being said I had an amh of 1.5 when I started and only got 2 eggs but we still went to collection. Both fertilised and one was put back in but it didn't take that time.
banshee (26-06-2014)
Sad news.. I had 14dpo bloods - 93 & 16dpo bloods - only 145. Not looking great.
Unfortunately this morning's pee stick looks even lighter. Went back to the fertility centre this morning so they can check numbers & progesterone, but yeah.. I think we might be heading towards a loss.
Oh Mrs J, I hope little bean is just off to a slowish start! All my love xx
@mrsjaguar don't give up hope. As I said on the other thread I know of another lady whose numbers were slow but she is 22 weeks now.
Sending you lots of positive vibes xxxx
Mrs Jag your numbers are within range, have you done another frer? Is it getting darker? Wfc told me 150+ at 14 days so your pretty much spot on - keeping everything crossed for you xx
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|Older translations
Crack (formerly known as IceBolt) is a recurring offensive spell in the Dragon Quest series and the first in the Crack family of ice spells. Introduced in Dragon Quest III, it has become a staple commonly learned by Mages and other users of offensive magic in the series.
Crack is often depicted as a sudden growth of ice crystals that cut into a single enemy. The crystals become larger, more abundant, and far more chilling in appearance as the spell family advances, often extending its target range along with its power.
Dragon Quest III[edit]
Crack is learned by Mages and Sages at level 5, and deals 25~35 points of damage for 3 MP.
Dragon Quest IV[edit]
Crack is automatically known by Borya at level 1, and deals around 10~16 damage for 2 MP. The reason for the lowered damage output is the concern over difficulty balance in the beginning of the second chapter.
In-Game Description[edit]
Pierces a single enemy with razor-sharp icicles. (Nintendo DS)
Dragon Quest V[edit]
Crack targets a single foe, and deals between 25~35 damage for 3 mp. It is learned by the following playable characters.
|Wiz pip
Dragon Quest VI[edit]
Milly learns this spell at level 9, and is the only character in the game who can cast it. It allows her to pierce an enemy for between 25~35 points of damage.
Dragon Quest VII[edit]
Crack is used by High Priestess Jacqueline, and can be learned by party members by reaching rank 8 of the mage vocation.
Dragon Quest VIII[edit]
Crack is learned by Jessica at level 10. It costs 3 MP to cast and initially deals between 20~30 damage until her wisdom exceeds 32, with a maximum of 44~52 once her wisdom hits 64.
Dragon Quest IX[edit]
Crack is learned by Mages at level 6 and Minstrels at level 8, and costs 3 MP. It pierces a single enemy with razor-sharp icicles, dealing 25~35 base damage before the caster's magical might reaches 50 and capping at 114~123 at 999 magical might.
Dragon Quest X[edit]
Crack is learned by magi at level 6 and by Minstrels at level 8. It costs 3MP to cast, and damage is calculated as Magical Might x 0.24 + 9.5 with an upper limit of 86~90.
Dragon Quest Monsters: Joker[edit]
Crack pierces an enemy with sharp icicles. It costs 2 MP to cast and can be learned from the Aquapothecary, Bang & Crack, Crack & Zam, Crack & Zap, Diamagon, Ice, Icemeister, Niflheim, and Woosh & Crack skillsets.


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Derby restaurants
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via newamsterdamlemonade: the Brown Derby restaurant, Wilshire Boulevard, Los Angeles, c. 1939. by John Swope.
Looking for THE dining experience that's not to be missed in Disney's Hollywood Studios? Look no further than The Brown Derby! 3. Old Hollywood Atmosphere Patterned after the famous Brown Derby restaurant in Hollywood California – this unique eatery displays caricature drawings of celebrities like Lucille Ball, Bette Davis, Charlie Chaplin, John Wayne and many ...
Hollywood Studios -- The Hollywood Brown Derby - (Ate there with my brother & nephew on our last trip.)
Disney Recipe: Grapefruit Cake at #Disney World's Hollywood Brown Derby Restaurant! #Disney #Recipe
laurence olivier and vivien Love among the stars list | Dear Mr. Gable – {The Brown Derby Restaurant} Part 1: The History
Interior Of The Brown Derby In Hollywood
Interior of the Brown Derby in Hollywood
#Disney #Recipe: Cobb Salad from Hollywood Brown Derby! Step by step recipe with pictures!
Banana Toffee Mousse on Cocoa Crunch Recipe Just in Time for Holidays from The Hollywood Brown Derby Restaurant at Disney's Hollywood Studios
The Brown Derby Restaurant, Los Angeles, 1954...... I remember this place...


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Views: 171, Replies: 4 » Jump to the end
Aug 5, 2016 11:37 AM CST
|These Aquilegia are doing better since I moved them to the cedar planter and started fertilizing once a week. Am I supposed to dead-head or prune these? I'm tempted because the dead blooms make it look kinda ratty.
"Love the people who treat you right and forget the ones who don't." - Chiune Sugihara
[Last edited by Brinybay - Aug 26, 2016 1:04 PM (+)]
| Quote | Post #1234444 (1)
Aug 5, 2016 12:32 PM CST
|They do look quite nice! Yes, deadhead away...You'll most likely see another flush of blooms!
Aug 26, 2016 1:03 PM CST
|You were correct! The other apparently is done blooming.
"Love the people who treat you right and forget the ones who don't." - Chiune Sugihara
Aug 26, 2016 1:06 PM CST
|It sure is pretty!
Aug 26, 2016 3:55 PM CST
|Don't deadhead your favorites. They will go to seed and you will have more plants next year. They are easy to move to your desired locations once they sprout.
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Monday, September 2, 2013
Broccoli and Bacon Salad
1/2 lb of bacon
8 C. broccoli florets
1 c. raisins
1/4 c. red onion, minced
1 c. unsalted sunflower seeds
Fry the bacon over high heat until the bacon is crisp, drain and remove from heat. Chop the bacon. Combine all of the ingredients except the sunflower seeds in a large bowl.
1 C. Mayo
1/4 c. sugar
3 TBSP. vinegar
Whisk all of the dressing ingredients together.
About a half hour before serving pour the dressing over the salad and mix well. Top with the sunflower seeds.
Enjoy and Happy Labor Day!
Posted by Debra Hawkins at 9:44 AM
Labels: Tasty Tuesdays
8 comments:
- Vanessa Barker said...
Yum!!! This looks so good. Can't go wrong adding bacon to anything!
- September 2, 2013 at 10:08 AM
- Jessica said...
I typically don't love broccoli but this is actually really calling out to me! Can't wait to try it! Thanks for sharing.
- September 2, 2013 at 10:14 AM
- Amber Brady said...
I love broccoli salad! It's one of my favorites!
- September 2, 2013 at 10:19 AM
- Whit said...
That salad looks so yummy and perfect for a labor day BBQ thank you for sharing the recipe I like really want it for lunch now :)
- September 2, 2013 at 10:20 AM
- Yvonne said...
This sounds like something I would definitely like - the dressing sounds delightful!
Yvonne @ TriedandTasty.com
- September 2, 2013 at 12:53 PM
- UtahCouponDeals said...
This sounds great. I love broccoli and this combo sounds delish. thanks!
- September 2, 2013 at 2:04 PM
- Kylie said...
I'm always looking for non-potato salad recipes for BBQs. Pinning!
- September 2, 2013 at 7:04 PM
- Guereca Family said...
Yum! I've made something similar, with cubed cheddar and no raisins. I think I might make it this week.
- September 2, 2013 at 11:43 PM
Subscribe to: Post Comments (Atom)


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Tom Beecher
As CEO, Tom leads Cartera with a singular vision-to make our platform reach its full potential, creating enhanced loyalty for our bank and airline partners, introducing new customers to our retailers, and making shopping more rewarding for millions of consumers. Formerly serving as CEO of Imagitas and a consultant at Bain & Co., Tom is a model of contemporary corporate leadership. Outside the office, Tom keeps active, frequently hitting the slopes with his family in Vermont and Utah.
Karen Cambray
Karen comes to Cartera with an impressive financial background, having spent twenty years in executive finance roles for several early-stage tech start-ups. Before coming to Cartera, Karen served as CFO and Vice President of Operations at Zeemote and as CFO of Groove Mobile. At Cartera, she is responsible for all-things finance, including accounting, legal and human resources. Karen was recently honored as CFO of the year by the Boston Business Journal.
Anamika Sengupta
As the Manager of Customer Care, Anamika plays an essential role in ensuring clear communication and issue resolution with many of our partners. Outside of work, she can be found enjoying Indian music, a good movie or the occasional Cadbury Egg.
Marc Mazzone
Heading up business development and partnership management, Marc plays an essential leadership role in the continuing success of Cartera. With over 20 years of experience in advertising sales, marketing communications and client services, he is responsible for directing the sourcing and merchandizing of all offers Cartera hosts over its platforms. Outside the office, Marc loves to practice and perfect his gourmet cooking, making delicious meals for family and friends.
Erin Warren
Erin Warren is responsible for all Cartera's marketing initiatives, helping to engage more online shoppers every day. Specializing in digital marketing, she has previously served as CMO of CollegeWeekLive, and as Vice President of Channel Marketing for Sallie Mae. Erin is also a two time Olympian, having competed in the Women's Luge in the 1994 and 1998 Winter Olympics. She currently sits on the Board of Directors for the U.S. Luge Association.
Brian Michon
Driving Cartera's technology strategy, Brian brings an incredible background of innovation and invention to Cartera. With degrees in computer science from both MIT and Stanford, he's served as VP of engineering at Intuit, leading the development of game-changing products like TurboTax and Quickbooks. At Cartera, Brian leads the company's development, operations and solution delivery teams. During his down time, you'll likely find him fiddling about with his many boats.
Andrew Ambroise
With over 7 years of quality engineering management experience, Andrew is a key player in making sure our partners' customers have a seamless shopping experience. He's also the impassioned coach of his son's basketball team and a generous web developer for family and friends' businesses.
MaryBeth Bell
With a career-long track record of developing domestic and international loyalty programs, Mary Beth (a.k.a. MB) heads our Relationship Management team, leading efforts to plan, implement and reach the goals of Cartera's many partners. Prior to Cartera, MB served in leadership roles at LoyLogic, CauseLoyalty and Upromise. When asked about her passions, she'll tell you they're reading a good book, nice beaches, and enjoying a fine cheese or two.
Shradha Jalan
Working with large and dirty data sets, Shradha uncovers many of the insights that inform marketing strategy and business growth for Cartera and our partners. She's also an outspoken foodie and will likely not stop until she's sampled all the world's cuisines.
Danielle Connor
As DMO, Danielle heads up merchandising strategy at Cartera, leading the Merchandising Operations team and constantly seeking new initiatives for revenue growth. In her free time, you'll often find her taking her son and two bulldogs (Lincoln and Zoe) out for long walks.
Cody Wood
With over 16 years of experience in web development, Cody wears many hats at Cartera, working on everything from UI development to business logic and databases. Additionally, if you ever feel the need to discuss old school, cheesy martial arts flicks, Cody is your guy.
Raina O'Hare
As UX product manager, Raina works to drive more shopping on Cartera's B2B client malls through user centric design and functionality updates. She also works with the Relationship Management and the Ad Sales teams to implement custom experiences and valuable ad inventory for clients and retailers.
Carolyn Bartlett
Carolyn has many responsibilities at Cartera, chief among them ensuring all content in our programs is accurate, up-to-date and entered properly. She is also one of Cartera's formidable athletes, having competed in the Disney Marathon (a whimsical but challenging run) on more than one occasion.
Manodnya Lele
Manodnya is one of Cartera's talented back office software engineers, working on enhancing and maintaining our processing systems. Outside the office you might find her taking part in a Bollywood dance concert, and if not that, definitely a rock-solid afternoon nap.


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5 Types of Prewriting Bubble Clusters and Spider Diagrams 1.The subject of the prewrite goes in the middle circle. 2.Each circle is numbered. The center bubble is the main idea and is labeled #1 3.The #2 bubbles are sub-headings off the main idea. #2 ideas are the basis for the topic sentences. 4.The #3 bubbles are concrete details and there must be at least two. They form the backbone of the body paragraphs. Each #3 must be at least 5 or more words.
3 Go on vacation s to Disneyland and the beach 1 Summertime 3 Barbecues in the back yard 3 more time to do pleasure reading 3 Catch up on movies I missed 2 family 2 daily routine 3 stay up late and sleep in 3 see my brothers and sisters more often
1 Summertime 2 family 2 Daily routine 3 Barbeques in the backyard 3 See my brothers and sisters more often 3 go on vacation to Disneyland and to the beach 3 stay up late and sleep in 3 more time to do pleasure reading 3 catch up on movies I missed
Outline Getting a Computer (#1) I.Picking one out (#2) A.Shopping around at different stores to compare (#3) B.Talked to salespeople about what I needed (#3) II. Setting it up (#2) A.Tried to read the manual but gave up (#3) B.Friend came to get it started and teach me (#3)
Line Clustering Subject: (#1)Spring—my favorite season of the year. Step 1: LIST List your ideas in any order. You need 6. --new leaves and flowers on the trees --warmer weather during the day and night --time to clean the house --school is coming to an end --Daylight Savings Time comes in April --baseball season/practice starts up again
Line Clustering, cont'd. Step 2: CATEGORIZE Categorize your ideas(think of ways you can group ideas together) A.Nature (#2) B.My daily routine and responsibilities (#2)
Line Clustering, cont'd. Step 3: LABEL Label each idea by category A. new leaves and flowers on the trees (#3) A. warmer weather during the day and night (#3) B. time to clean the house B. school is coming to an end B. Daylight Savings Time comes in April B. baseball season/practice starts up again
Columns/ (#1)My Two Best Friends (#2)Cheryl (#3) known me since we were in kindergarten (#3) we have 4 classes together each day (#2)Joe (#3) lives down the street from me (#3) we will be taking driver's training together next summer
Thesis Statement 1.My high school is the best one around. Yes 2. I have gone to East High School for three years. No 3. Our football team is better than last year's. Yes 4. I hate going to the mall for Christmas shopping. Yes 5. My family went to Disneyland last summer. No
Thesis Statement 6. Volleyball is the best sport to play. Yes 7. Little Women was a fascinating book. Yes 8. My bedroom is a pigsty. Yes 9. School is a cool place to be. Yes 10. We have 4 required courses to take this year. No
Thesis Statement, cont'd. Come up with your own thesis statements. Subject: Sports Subject: Music Subject: Changing schools
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