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A San Francisco based General Contractor are looking for both senior and junior carpenters to join their team....
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Need Experienced Journeyman Carpenters with great attention to detail. Must be able to problem solve and work as a team....
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Samsill Angle-D Ring Binder
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- Product Type:Ring Binder
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Canongate, EdinburghIntégréTéléchargement
Publishing in Scotland and e-lending Marion Sinclair Publishing Scotland Vital Stats 100+ active companies in Scotland, producing 3000 titles p.a. Most are small or medium-size companies £350m turnover (similar to salmon farming & cashmere) Employs 1600 people directly 2 No such thing as a typical Scottish publisher, but… 4-12 staff & turnover between £100k and £2m Skills profile - any degree Diverse range of titles, non-fiction is 70% of total Uses overseas distributors, printers, reps Embracing digital publishing 3 Canongate, Edinburgh 4 B & W, Edinburgh 5 Birlinn, Edinburgh 6 Saraband, Glasgow 7 Waverley/Gresham, Glasgow 8 Sandstone, Highlands 9 Freight, Glasgow 10 The literature scene The Edinburgh International Book Festival – largest in the world Strong literary heritage Publishing in all 3 languages: English, Gaelic and Scots A robust public funding system Large number of literature organisations Culture devolved to the Scottish Government 11 What is the market reality? Huge discounting Amazon 60% Wholesalers 55% Library supply 55% The strength of London publishing Marketing spend still problematic – not enough to have good books They are more nimble and niche Scottish books have a defined market/Scottish writing currently very strong Niche players can reach their audiences more easily 12 Threats Abundance of (often free) content Power of mega corporations Fewer High St retailers Dilution of reading habit Digital publishing is complicated… 13 Opportunities New formats for content Consumer expectations constantly changing Devices get more sophisticated Cheaper distribution costs Publishing in English language – global reach 14 Publishing Scotland Set up in 1974 by 12 publishers Funded by Creative Scotland, member subscriptions and activities Two types of membership: Publisher Network: supply services to industry 64 publishers & 44 network members 15 Collective infrastructure… 16 The winds of change… Amazon selling more Kindle ebooks than print books The UK's biggest book retailer Amazon now sells more ebooks than hardbacks and paperbacks combined, the company has said. For every 100 print books sold through the site, Amazon said it sold 114 titles for its Kindle e-reader device. 17 E-lending - the view from the publishers Publishers want libraries to be successful in digital lending but not so successful that they significantly inhibit the purchase of the publishers' titles. Writers and publishers need fair compensation for their efforts. Support for lending but still have major concerns around technological, operational and financial challenges. 18 E-lending – the library view "Denying libraries unfettered access to ebooks threatens the library mission" Cost is a major issue – more expensive to purchase for libraries than for general public "The overriding eBook issues for libraries continue to be the withholding of content and the imposition of problematic and differing licence terms and conditions by major trade publishers." 19 The Sieghart Review (UK, 2013) As far as is possible, the digital loan of a book should emulate its printed counterpart Library members should be able to borrow digital books from their libraries remotely Each copy of a digital book should only be loaned to one reader at a time, just as with a physical book Digital copies of books should be deemed to deteriorate, ensuring their repurchase after a certain number of loans The extension of the Public Lending Right (PLR) to cover digital, audio and e-audio books 20 Models across the world Denmark Libraries provide their cardholders with downloadable ebooks Service set up by government in 2011 Payment to rights-holders on a per use basis Majority of large publishers pulled out after a year Set up their own system – shut down due to low use 21 The Netherlands Access is provided to 5,000 Dutch eBook titles and payment to publishers is on a per loan basis with the amount declining for older books. Dutch residents pay an annual charge to use the public library so the notion of "user pay" for eBooks is not a foreign concept The Dutch government established centralised budget for purchasing ebooks for libraries 22 Quebec eBooks purchased through the BIBLIOPRESTO.CA licence have a maximum loan limit of 55 with no annual limit. On site reading in libraries is permitted and falls outside the loan limit. Individual libraries set their circulation policies including the number of eBooks which can be borrowed at one time, the length of the loan period etc. Providing library users the option to purchase the eBook from a Quebec bookseller can be implemented at the discretion of the library. eBooks are sold to libraries at the same price they are offered to the general public. 23 Australia – the 8 principles Importance of libraries role in promoting a reading culture Models for the supply should be as consistent and transparent as possible Increase availability of ebooks through libraries Continuity of access even if distributor ceases business Fair remuneration for writers and publishers Fair pricing Protecting copyright and other rights Device neutral ebooks 24 Scotland Two ways to approach this: neutral – any book will do – doesn't matter where it's from New scheme for Scottish books 20% of books on Overdrive system are Scottish Desirability of setting up scheme for 20% as opposed to 80%? An indie solution? A pilot with a curated list of books? (Meets need to support cultural 25 Final word… "There is the appetite for collaboration between publishers and libraries in Scotland. We need to think about the implications for copyright, for what's happening elsewhere in the UK, for exclusive deals that the publishers and librarians may have worked out elsewhere, for not being seen to be operating as a cartel, and for a host of other considerations that need to be discussed, not least solutions that focus on the medium to long term." 26 Publishing in Scotland Further info on world e-lending issues and models – http://www.ifla.org/files/assets/hq/topics/elending/documents/2014_ifla_elending_background_ paper.pdf 27


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Brendan Kelleher Rose
Brendan Kelleher Rose is a professional in the game industry.
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display racks
Exhibition Supplies & Services, Retail Stores, Display Racks
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Place of Origin: Shanghai, China (Mainland)
Brand Name: Getell
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Size: customised
color: customised
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1,High quality
2,Durable and fashionable
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4. It can be used for supermarket/ retail store or some other places.
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Oil Loses Gains as Inventories Climb to 86-Year High: Chartby
Oil erased gains after the Energy Information Administration reported U.S. crude inventories rose by 2.15 million barrels to the highest since 1930. That contradicted a report from the American Petroleum Institute late Wednesday that supplies fell.
Before it's here, it's on the Bloomberg Terminal. LEARN MORE


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Stockport County are facing an uncertain future after the Coca-Cola League One club entered administration yesterday.
The Football League acted immediately by imposing a ten-point penalty that drops Jim Gannon's team four places to seventeenth in the third tier. The penalty would have been carried over to next season if Stockport were relegated to League Two, but their healthy goal difference means that they are effectively safe from relegation even with their revised tally of 50 points. Only extraordinary wins by the four clubs immediately below them can send them down after this weekend's final round of matches.
Stockport may


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Definition of 'astragalus'
noun plural -li (-ˌlaɪ)
anatomy another name for talus1
Collins English Dictionary. Copyright © HarperCollins Publishers
Word origin of 'astragalus'C16: via New Latin from Latin: astragal
nounWord forms: plural asˈtragaˌli (əˈstrægəˌlaɪ ; əstragˈəlīˌ)
Webster's New World College Dictionary, 4th Edition. Copyright © 2010 by Houghton Mifflin Harcourt. All rights reserved.
Word origin of 'astragalus'L, astragal
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Beautiful Beads
Bonus: Get our newsletter & special offers for free. We will not share or sell your email address. View our Privacy Policy
Latest Comments
"I agree with those who said projects with glass, glitter, etc., are adults-only projects. I would also add to the list any project that involves a lengthy set of instructions or takes a long time to complete, as I think kids would just get frustrated and impatient."
"I can not even tell you how cute these penguins are. I love them. Reminds me of Happy Feet an that is just what I will make them. So adorable and so simple to make using a water bottle and a sock. Now how many ones do I have that do not have mates and that hat gives the penguin some personality. How about making a few and changing them a little and making your own Happy Feet collection foe a mantel or centerpiece. How cute will that be. Great tutorial."
"A cute colorful wreath for getting in the spring mood. Soft pastels to remind us of the up coming beautiful spring days with a cute fun and easy project that can be done with the whole family inside or out on the patio enjoying the beautiful weather. So inexpensive and a great idea to use the food colors to paint the ends and you can even teach kids how colors mixed together make different colors. You can get creative with this wreath by using the colored cupcake liners, glitter or even embellishments. Super tutorial and a great spring break project. Let's see some pictures of creative minds."
"Home decor pieces, such as furniture crafts or complex wall art. Not for kids because of skill level and also because they probably wouldn't care about the finished project!"
"I love it. It is simple once you get the idea. And think how versatile this pattern would be. You can dress them up by using glitter beads or switch colors for the seasons. Green and red at Christmas, pink or purple for Easter, brown and orange for thanksgiving and so on. I am going to have to experiment a little with them."
Chinese Beads Tutorial
By: Candie Cooper for Be Savvy, Be Crafty
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If you're looking for creative and fun beaded jewelry ideas, check out this project for Chinese Beads Tutorial from Candie Cooper. These tiny little balls of beads are so cute, and will make fantastic earrings for yourself or for one of your friends! It's a simple jewelry craft with beads, and if you like beaded jewelery, you'll want to create this cool new craft!
- 30 beads of any shape and size (just be sure the hole in the bead is big enough for the cord to pass through twice)
- good quality nylon cord
- bit of glue
- Cut 20 iinches of cord and double it over so the ends meet and string 5 beads onto the left end/side of the tail.
- Thread the right end of the cord through the 5th bead in the opposite direction that the left tail is going-I call this a 'cross'.
- Pull the two ends snug so it makes a star in the middle of your bead cluster.
- String 4 beads onto the left tail.
- But on the 4th bead thread the right tail through in the opposite direction that the left tail is going (I call this a cross).
- Look carefully at the orientation here. At the top is the original 5 beads and in my fingers is the 4 beads. The right cord comes out and goes into the bead directly to the right of it.
- This is how it should look. Notice how the cord looks like it is going through two beads side by side.
- String 3 beads onto the left tail and cross the right tail through the 3rd bead.
- String the right tail through the bead directly to the right of it again.
- Repeat the last three steps two more times so that you will have a total of 4 clusters around your central star at this point.
- Now run your right tail through the two beads to the right of the bead where the right tail comes out (as seen in picture) and string 2 beads onto the left tail.
- Cross the right tail through the 2nd bead and pull the two ends snug. This completes the top half of the bead, making sort of a dome shape.
- The right tail goes through the bead just next to it.
- String 3 beads onto the left tail.
- Right tail goes through the 3rd bead, making the cross.
- Now this time, the right tail goes through two beads to the right of it.
- String 2 beads on the left tail.
- Right tail crosses through the second bead.
- Repeat the last the last three steps two more times!
- String the remaining bead on the left tail.
- The left tail with the bead on it goes across and through the bead on the left, then it keeps going through the remaining 3 beads in the cluster of 5. Same goes for the right tail except it goes through the right side, opposite the left. Remember that the cord should make a triangle at each bead junction and the cord must pass through each bead twice. Tie the tails in a knot where they meet up.
- Trim the ends and dot the knot with some glue to secure.
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sunshine6957 90910 35
Nov 05, 2011
Could you please do a demo that shows the thread? It is very hard to see the clear thread and the placement of the beads and where the thread is going. Maybe use black thread and white beads. Thank you very much for sharing, I really like the design and have some nice swarovski bicones for this project.
Sep 15, 2011
@tahdeah 9098606, Please contact the pattern designer directly for help. The designer is specified in the byline. --Editor of FaveCrafts
tahdeah 9098606
Sep 14, 2011
down toward the end it get very confusing and hard to follow
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Susan Hadley MD Patient Reviews
- Infectious Disease Boston, MA
Vitals cannot verify whether or not this professional is currently practicing. We recommend that you attempt to contact the provider to verify their status. Please email us at firstname.lastname@example.com if you have any additional information.
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As an RN I would rate Dr. Hadley as one of the best. She literally saved my husband's life. He developed a rare and difficult to diagnose disease. Without her experience and knowledge, he would not be alive today.


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Last Refuge of Scoundrels
By (author) Paul Lussier
Format: Hardback
Normal Price: $57.04
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Last Refuge of Scoundrels by Paul Lussier
Book DescriptionEarly critical acclaim from Pulitzer Prize-winning scholars and best-selling authors Studs Terkel, Jonathan Kozol, Robert Coles, Howard Zinn, John Ferling and Winston Groom: "Last Refuge of Scoundrels" is the bottom-up story of the American Revolution brought to life vividly, compellingly, suggestively. It's a story that gives America its past in a manner worthy of comparison to Tolstoy's effort to understand and render history and does so in a manner that's rich, rambunctious, exploding with vitality and bubbling with wild humor. A delightfully irreverent look at the Revolution, it tells the story of John Lawrence a naive young merchant's son who finds love and his life's purpose in Deborah Simpson, a spy working in collusion with George Washington to lead An unsung army of ordinary Americans against the self-interested Founding Fathers as much as the bumbling Brits. "Last Refuge of Scoundrels" weaves meticulous research and fantastical fable into a poetic tale that's at once a rollicking romp, a haunting love story and a revisionist historical epic.
Buy Last Refuge of Scoundrels book by Paul Lussier from Australia's Online Bookstore, Boomerang Books.
Book DetailsISBN: 9780446523424
(229mm x 152mm x 22mm)
Imprint: Little, Brown & Company
Publisher: Little, Brown & Company
Publish Date: 8-Feb-2001
Country of Publication: United States
Other Editions...
Books By Author Paul Lussier
Last Refuge of Scoundrels, Paperback / softback (March 2002)» View all books by Paul Lussier
From George Washington to Benjamin Franklin to those whom history has neglected, the human side of the American Revolution that was never taught in school is told from the perspective of two star-crossed lovers.
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Published on March 25th, 2010 | by Janine Popick1
eMarketer: Combining the Strengths of Social and Email
eMarketer reported on a study by Strongmail that said that this year social media will make email marketing more powerful.
"Even though people are spending more time using social media, they are not abandoning e-mail," said Debra Aho Williamson, eMarketer senior analyst and author of the new report, "Maximizing the E-Mail/Social Media Connection." "The two channels can help each other, offering the opportunity for marketers to create deeper connections."
More than 40% of the businesses surveyed said that integrating email and social media was one of their most important initiatives for 2010.
We couldn't agree more with this report, and from what we're seeing, small businesses are using the VerticalResponse Social Sharing feature which posts a hosted version of an email marketing campaign to Twitter and Facebook to get more reach. It seems to be working since a pretty high percentage of our customers are using the feature.
Are you publishing your emails to Twitter and Facebook? If so how is it working?
© 2010 – 2013, Janine Popick. All rights reserved.
One Response to eMarketer: Combining the Strengths of Social and Email
Could you please show an example of a hosted email campaign.


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Images of Aaron Ashmore
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For images of Aaron Ashmore portraying the Smallville character Jimmy Olsen see Category:Images of Jimmy Olsen.
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Morio, Béatrice Fardet, Anthony Legrand, Philippe and Lecerf, Jean-Michel 2016. Involvement of dietary saturated fats, from all sources or of dairy origin only, in insulin resistance and type 2 diabetes. Nutrition Reviews, Vol. 74, Issue. 1, p. 33.
Roy, N.C. Bassett, S.A. Young, W. Thum, C. and McNabb, W.C. 2014. Food Structures, Digestion and Health.
Chuah, Li Oon Ho, Wan Yong Beh, Boon Kee and Yeap, Swee Keong 2013. Updates on Antiobesity Effect ofGarciniaOrigin (−)-HCA. Evidence-Based Complementary and Alternative Medicine, Vol. 2013, p. 1.
Walhin, Jean-Philippe Richardson, Judith D. Betts, James A. and Thompson, Dylan 2013. Exercise counteracts the effects of short-term overfeeding and reduced physical activity independent of energy imbalance in healthy young men. The Journal of Physiology, Vol. 591, Issue. 24, p. 6231.
Das, Sai Krupa and Roberts, Susan B. 2012. Present Knowledge in Nutrition.
Holway, Francis Biondi, Bibiana Cámera, Karen and Gioia, Fernando 2011. Ingesta nutricional en jugadores adolescentes de fútbol de elite en Argentina. Apunts. Medicina de l'Esport, Vol. 46, Issue. 170, p. 55.
Jones, Peter J.H. and MacKay, Dylan 2010. Obesity Prevention.
Llaneza, Placido González, Celestino Fernandez-Iñarrea, Jose Alonso, Ana Arnott, Ignacio and Ferrer-Barriendos, Javier 2009. Insulin resistence and health-related quality of life in postmenopausal women. Fertility and Sterility, Vol. 91, Issue. 4, p. 1370.
Zhang, Z.C. Lian, B. Huang, D.M. and Cui, F.J. 2009. Compare Activities on Regulating Lipid-Metabolism and Reducing Oxidative Stress of Diabetic Rats ofTremella Aurantialba Broth's Extract (TBE) with Its Mycelia Polysaccharides (TMP). Journal of Food Science, Vol. 74, Issue. 1, p. H15.
Avramoglu, Rita Kohen Basciano, Heather and Adeli, Khosrow 2006. Lipid and lipoprotein dysregulation in insulin resistant states. Clinica Chimica Acta, Vol. 368, Issue. 1-2, p. 1.
Cannon, Geoffrey 2006. Out of the Box. Public Health Nutrition, Vol. 9, Issue. 04,
This paper discusses possible consequences of energy excess throughout the life cycle. Firstly we consider the effects of foods on hunger, satiety and satiation. Also, the changes in food availability and consumption in relation to changes in social and economic determinants of energy excess. The relationship between physical activity and energy intake (EI) is also considered. Secondly we explore the definition of energy excess and the metabolic effects of macronutrients (mainly in relation to fuel partitioning oxidation/storage) on energy balance. The cellular and molecular regulation determined by specific genes involved in lipogenesis, fuel partitioning and/or in energy dissipation are explored. Thirdly, we examine the main consequences induced by energy excess and positive energy balance, starting with the alterations in glucose utilisation (insulin resistance) leading to type 2 diabetes and the linkage of energy excess with other non-communicable diseases (NCDs). Biological, social and psychological consequences during perinatal, childhood and adolescence periods are specifically analysed. Fourthly, the transition from energy deficit to excess, under the optic of a developing country is analysed with country examples drawn from Latin America. The possible role of supplementary food programmes in determining positive energy balance is discussed especially in relation to pre-school and school feeding programmes. Fifthly, we deal with the economic costs of energy excess and obesity related diseases. Finally, some areas where further research is needed are described; biological and genetic determinants of individual and population energy requirements, foods and food preparations as actually consumed, consumer education and research needs on social determinants of energy imbalances.
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Right on the beach / lake with an incredible view, great vibe, roof-top bar, fun staff, plenty of day & night... More Info »
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The Hostel Canasvieiras remains open all year! Located on the beach of Canasvieiras which is one of the most... More Info »
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text:
We sold this Lagoon 620 originally in 2013. It has been maintained professionally to a very high standard. Used for 18 months the Owner is now upgrading.
Layout is the standard Lagoon 5 cabin version, with the starboard aft cabin modified into an office /dressing area. Both bow fore-peaks are converted with twin bunks in the port side and a small double in the starboard side. The galley 'down' is located in aft port hull.
220V. Upgraded Hydranet sails with spinnaker and gennakers. Tenderlift, Air Con, Watermaker and full suite of electronics... no expense spared in equipping this Lagoon 620 for serious cruising.
Seriously for sale, as the owner is moving to a larger catamaran. Available to view in Florida. CALL NOW TO ARRANGE VIEWING!
Infused FRP + balsa core with polyester and high quality anti-osmotic resins. Hull bottom and keels in solid infused laminate
Infused balsa core structural bulkheads
Grey paint coat in bilges
White gel coat hulls
White gel coat decks with non skid areas
• 1 deck hatch for technical compartment access
- house battery bank
- dedicated area for generator (optional), chargers
(opt.), inverter (opt.), dive compressor (opt.)
• 2000W 24V electric windlass on deck with horizontal gipsy (14mm chain) and remote control
• Chain locker to starboard of the windlass.
• 3 deck lockers 2 to port and 1 to starboard.
• Composite longitudinal compression beam including anchor chain run, forestay chain plate, staysail and gennaker tack fittings (staysail and gennaker optional).
Deck Hardware
Harken deck gear
1 X STEVA 74.2 mainsail halyard electric winch
3 X STA 74.2 ELECTRIC winches : 2 for genoa sheets and 1 for reefing lines and traveller lines
Cockpit and salon on one level (no steps)
Teak cockpit floor
L shaped settee
Storage under settee
Large teak cockpit table made of 2 separate tops
3 door cockpit locker with sink and resin countertop (Iro G120)
Cockpit fridge 80 L (21 US Gal)
8 spotlights recessed in hard top ceiling with dimmer switch
Storage in cockpit ceiling
Aft crossbeam with 4 storage lockers, sun lounging area, dedicated space for 2 X 10-person life raft, stainless steel railing.
5 CABIN VERSION : Galley in port hull with modified Owners Cabin in starboard hull.
Access from the cockpit through sliding & locking door with latching mechanism inside and out. Half way latching points
Storage under floors with hinged panels and lifting arm
4 opening hatches on the front windows
Forward window curtains
Companionway steps port and stbd against coachouse bulkhead
Companionway steps port and stbd behind mast bulkhead
Lockers on mast bulkhead including
Dish cupboard
Couch for 3 with « lazy boy » lounge chair
1 coffee table
Bar cabinet forward of the settee
Space for flatscreen TV on electric lift (option)
1 X 220 V outlet
Starboard side
Couch for 5 people
2 coffee tables convertible into one large dining table (telescopic legs)
4 stand alone chairs
1 X 220V outlet
Port forward cabin
Access from the forward companionway via wooden door
Queen size bed (2,05 m/6'9" X 1,60 m/5'3")
with side access and wood slats under mattress
Upholstered bed head board
Under bed storage
Bedside storage
Hanging locker with light and shelves
Storage locker on outboard side
1 opening port hole
Large one way fixed hull window
Opaque window curtains
Opening deck hatch with mosquito screen and blind
Direct access to the bathroom (mirror behind door)
Minimum headroom 2.05m (6'9'' )
2 x 220V outlets
Cabin door with lock
Upholstered panels on ceiling liners
General cabin lighting with two way switch by bed side and reading lights
Forward port cabin bathroom
Solid resin countertop ("Coffee Bean" colour) with built in washbasin
Separate shower stall with plexiglass door
Non skid floor in bathroom and shower stall
Vanity cabinet and mirror
Electrical Tecma fresh water toilet
Toilet paper holder
Soap holder
Wall mounted towel holder
Headroom 2.05m (6'9'')
Opening deck hatch with mosquito screen and blind
3 spotlights
Access from cockpit through sliding glass door and steps
Access from the salon through companionway steps
2 opening deck hatches
Outboard side
White solid material countertop (White Ice Corian®)
2 waste bins under countertop for selective refuse
1 double-door side by side fridge/freezer 220V 500l (132 US Gal) with ice maker and dedicated 24/220V inverter
Dedicated space for washer/dryer (optional)
Dedicated space for dish washer (optional) + upper storage
3 X 220 V outlets
Lower storage with shelves
Opening port hole
1 large one way fixed hull window
1 double stainless steel sink with stainless steel mixer tap
Inboard side
White solid resin countertop (Ice White Corian®)
4 burner butane stove
Electric hood over the stove (option)
Butane oven 52L (14 US gal)
Space for multifunction micro-wave oven (option)
Upper storage cabinets
Lower storage cabinets with drawers and shelves
Ceiling and under cabinet lights
2 Volvo D3-150 HP Diesel engines, 3000 rpm. Upgrade
Engine throttles and control panel on port steering station on flybridge
Conventional stainless steel propeller shafts with "p" brackets
2 folding propellers
Engine access through large deck hatches Stainless steel gas struts on hatches
Ventilation system (natural aspiration and forced extraction)
1 x 220 V outlet per engine room
Engine rooms lights
Sound insulation of engine compartments: foam on bulkheads
220V AC Circuit
2 outlets per cabin (owner's cabin : 3),5 in the saloon, 4 in the galley, one per gangway, 1 per engine compartment, and 1 in the technical compartment
220V electric panel with power source selector, voltmeter
30 Amp dock inlet in the aft transom with 15m (49' 3" feet) shore power cord
24 V circuit
24 V 420 Ah gel service battery bank (840 Ah optional)
24V electrical panel with battery bank monitor
Breaker-box for the 24V system
2 engine driven 110 Ah 24V Mastervolt alternators
12 V circuit
1 X 12 V 50 Ah start battery per engine
2 X 12 V Mastervolt alternators
1 X 12 V 50 Ah start battery for the generator (option)
Access from cockpit via stairway with teak steps on stainless steel frame
Flybridge access closing system
2 helm stations including
1100 mm (3'7'') diameter wheels
Navigation instruments pods
Engine throttles and control panels on port steering station
Cushions for settees + backrest
1 steering compass each
Windlass control on port steering station
Large settee across entire width of flybridge
''L '' shaped settee with coffee table
All lines led to forward part of the flybridge cockpit around 4 winches
4 lines storage boxes
Recessed sun lounging area aft of mast base
1 storage locker (housing for optional flybridge fridge)
Settee and sun lounging cushions are optional
Full Batten double thickness 146m2 (1571 sq Feet) « Dimension Polyant » - type Mainsail.
3 reefs.
Double thickness 97m2 (1044 sq feet) «Dimension Polyant » - type furling genoa.
UV protective strip.
Mast and boom in white lacquered aluminium
FRP longitudinal crossbeam
Aluminium transversal crossbeam
Adjustable lazy-jacks with spreaders
Running rigging
1 double purchase spectra mainsail halyard
1 spectra Genoa halyard with tension adjustment track at mast base.
1 boom topping lift
3 reefing lines
Genoa sheets
Mainsail sheet led back to winches via boom
Main traveller adjustment next to port side winches
Electric genoa furler with control on flybridge
Pulpits with wooden seats
840mm (2' 9") stanchions, triple lifelines, 1 lifeline gate on each side.
teak toe rail
|Sales status:
|Year built:
|Length (m):
|Beam (m):
|Engine manufacturer:volvo
|300.0 hp
|Fuel Capacity:
|172 liter
|Fresh water capacity:
|63 liter
|Model Year
|Waterline length
|59.75 feet
|Max Draft
|5.08 feet
Surprisingly comfortable for coastal cruising and excellent for fishing, the Merry Fisher 705 features ...
£ 38,488
VAT Incl. / Paid
Commissioned in 2008 and now on the market at a very attractive price, the Aquador 23 HT is in good, clean ...
£ 55,675
VAT Incl. / Paid
a very roomy starter family cruiser in very good condition great for weekends away and coastal cruising.
£ 14,530
VAT Incl. / Paid
A nice example of this lifting keel cruiser with benefit of recent new Beta inboard diesel. PRICE REDUCED? 12000
£ 5,872
VAT Incl. / Paid


text: Close Meet Starla: The rock for her strong family KING 5's Greg Copeland shares the story on the strength within one Gig Harbor family. wsts2 7:32 AM. PDT October 24, 2016 More Stories Widespread power outages impact thousands Jan. 6, 2017, 1:31 p.m. Flu epidemic: state could soon step in to help Jan. 6, 2017, 6:37 a.m. What the Seahawks are saying about Golden Tate Jan. 6, 2017, 9:22 a.m.


text: Indian actress Rakhi Vijan made her mark in Indian television circuit with her loud mouth character role of Sweetie in the comic sitcom "Hum Paanch" aired on Zee TV. She has amazing sense of humor and comic timing on/off screen and has is now sister-in-law to bollywood actress Raveena Tandon. She became household name when she was seen in TV serials like Dekh Bhai Dekh, Cinhcinnati Bublaboo, Hum Hain Dilwale and Banegi Apni Baat. Actress Rakhi Vijan was also seen in few bollywood films in glam doll roles. But those films did not earn her the status she expected and so she doesn't like to discuss about them.


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text:
Lou X.-D.,Fudan University |
Wang H.-D.,Fudan University |
Xia S.-J.,Fudan University |
Skog S.,Sino Swed Molecular Bio Medicine Research Institute
Fudan University Journal of Medical Sciences | Year: 2014
Diabetes mellitus and its associated micro- and macrovascular complications have posed a great threat to public health and become the main cause of morbidity and mortality burden to state economy. Recent studies have raised that epigenetics may play an important role in the pathology of diabetic vascular diseases, which refers to phenotype changes that are not related to the underlying DNA sequence, yet the alterations in gene expression can possibly be inherited into next generation. Furthermore, UKPDS and DCCT-EDIC demonstrate a phenomenon called metabolic memory, even if the blood glucose level is controlled in an ideal state, vascular inflammation still persists. Although epigenetics has not been fully elucidated, it provides a new insight into the pathogenesis of diabetes and is expected to become the targeted therapy for severe diseases. Source
Effects of resveratrol on the expression and DNA methylation of cytokine genes in diabetic rat aortas
Lou X.-D.,Fudan University |
Wang H.-D.,Fudan University |
Xia S.-J.,Fudan University |
Xia S.-J.,Chongqing Medical University |
And 2 more authors.
Archivum Immunologiae et Therapiae Experimentalis | Year: 2014
This paper studies the expression of proinflammatory cytokines such as IL-1β, IL-6, TNF-α, and IFN-γ and anti-inflammatory cytokines such as IL-10 in diabetic rat aortas, the effects of resveratrol on these cytokines, and the potential epigenetic mechanisms involved. The experiment was performed on rats divided into four groups: normal group (NC), normal interventional group (NB), diabetic group (DM), and diabetic interventional group (DB). The NB and DB groups were treated with resveratrol. After more than 3 months, the rats' aortas were removed and analyzed for cytokines by using immunohistochemistry, Western blotting, real-time PCR, and methylation-specific PCR. Histological localization of these cytokines was mainly found in the arterial intima of diabetic rats. The protein and mRNA expression levels of IL-1β, IL-6, TNF-α, and IFN-γ were significantly higher in the DM group than in the NC group (p < 0.05), whereas in the resveratrol-treated groups (NB and DB), the levels were relatively lower than those in the corresponding groups. The DM group showed reduced levels of DNA methylation at the specific cytosine phosphate guanosine sites of IL-1β, IL-6, TNF-α, and IFN-γ, relative to those in the NC group (p < 0.01), and these levels were increased by resveratrol. In contrast, IL-10 was dramatically methylated and showed decreased expression in response to high glucose, and resveratrol reversed this effect. These results demonstrate that the inflammatory response is involved in diabetic macroangiopathy. Resveratrol inhibits the expression of proinflammatory cytokines and thus may have a protective effect on the aorta in hyperglycemia. Thus, DNA methylation, an epigenetic gene silencing signal, may be responsible for these two phenomena. © 2014 L. Hirszfeld Institute of Immunology and Experimental Therapy. Source
Xu Y.,Nanjing University |
Xu Y.,Nanjing Southeast University |
Liu B.,Nanjing University |
Shi Q.-L.,Nanjing University |
And 8 more authors.
International Journal of Clinical and Experimental Medicine | Year: 2014
Objectives: The sensitivity and reliability of the biomarkers thymidine kinase 1 (TK1) and Ki-67 were studied in relation to clinical features and prognosis of survival for pathological-T1 (pT1) lung adenocarcinoma patients. Methods: TK1 and Ki-67 expression was determined in 80 patients with pT1 adenocarcinoma of the lung and in 20 specimens from normal lung tissues, using immunohistochemistry. Results: TK1 was found in most lung tumor cells both in the cytoplasm and the nuclei. The positive labelling index (LI) for total TK1 was significantly higher than that for Ki-67. There was a significant correlation between the LI of total TK1 and lymph node metastasis, degree of tumor invasion and pathologic stages, which was not found for Ki-67. In addition, the overall 5-year survival of patients was statistically significant different between low and high levels of TK1 expression, but not in cases of Ki-67. A multivariate analysis revealed that expression of TK1, lymph node involvement and TNM pathology staging could serve as independent prognostic factors for the disease progression of pT1 lung adenocarcinoma patients. Conclusions: Compared with Ki-67, TK1 is a more reliable proliferation index in pT1 adenocarcinoma of lung, which can evaluate the invasion and the prognosis of tumor. © 2014, E-Century Publishing Corporation. All rights reserved. Source
The proliferation marker thymidine kinase 1 level is high in normal kidney tubule cells compared to other normal and malignant renal cells
Luo P.,Wuhan University |
Wang N.,Karolinska University Hospital |
He E.,Karolinska University Hospital |
He E.,Sino Swed Molecular Bio Medicine Research Institute |
And 5 more authors.
Pathology and Oncology Research | Year: 2010
The activity of the proliferation related enzyme thymidine kinase 1 (TK1) was reported to be 3-fold higher in extracts from normal kidney tissue as compare to renal carcinoma extracts [3]. To verify these unexpected results, determinations of the protein levels of TK1 in normal kidney and in samples from different types of renal cell carcinoma (RCC) were done with immunohistochemistry and Western blot analysis. Two anti-TK1 peptide antibodies reacting with different TK1 epitops were used. TK1 levels were high in tubule cells as compared to glomerulus cells and connective tissue cells, while an intermediary TK1 was observed in renal cell carcinoma (RCC) cells. Western blot analysis demonstrated high levels of TK1 in extract from normal kidney, and lower levels of TK1 in the RCC extracts. The specificity of TK1 staining was demonstrated in competition experiments with excess TK1 antigen. The high TK1 levels in normal kidney tubule cells suggest that they are in a form of activated G1-state. The relatively low TK1 level in RCC, representing TK1 expression in S-phase cells, is in accordance with the low overall proliferation rate of these tumors. These results suggest that cell cycle regulation of TK1 in normal tubule cells differ from that in other type of normal and malignant renal cells. © Arányi Lajos Foundation 2009. Source
Sun J.,Fudan University |
Lou X.,Fudan University |
Wang H.,Fudan University |
Sollazzo A.,University of Stockholm |
And 4 more authors.
International Journal of Diabetes in Developing Countries | Year: 2015
The increased oxidative stress in diabetes is known to contribute to the development of diabetes. We investigate whether serum 8-hydro-2′-deoxyguanosine (8-oxo-dG) is associated with diabetes at the time of first diagnosis and evaluate whether it can be used as a reliable biomarker for the oxidative stress in diabetes. The study was designed as a case control study with two groups: patient with diabetes and control. The diabetes group consisted of a total of 28 patients consulting the hospital for the first time and definitely diagnosed for diabetes, and the control group was composed of 65 healthy subjects. Serum 8-oxo-dG was measured by a competitive enzyme-linked immunosorbent assay (ELISA) kit, specially developed to minimize cross-reaction of 8-oxo-dG antibody with serum guanosine. The average serum 8-oxo-dG levels in patients with diabetes and controls were 0.72 ± 0.41 and 0.24 ± 0.14 ng/mL, respectively, statistically significant (p < 0.001). The 8-oxo-dG value was significantly higher in women with diabetes, compared with men with diabetes (p = 0.028). The sensitivity and the specificity of the 8-oxo-dG ELISA assay were 0.80 and 0.96, respectively, and the ROC value was 0.93. This study suggests that increased oxidative stress has an important role in the pathogenesis of diabetes. Serum 8-oxo-dG may be a useful clinical biomarker for the early diagnosis of stress-related diseases, e.g. diabetes and its management. © 2015, Research Society for Study of Diabetes in India. Source


text:
The holidays are just around the corner as the thoughts of many Americans are becoming flooded images of food, friends, family, and football. Before we all go our separate ways for Thanksgiving, the president and chief of all things Dirtybird Records related would like to occupy your mind for just 5 mins as Claude VonStroke unveils a new track that may put a boogie in your step come Black
out Wednesday. His latest offering is a straight up electro-house banger that will available for download tomorrow on Beatport. Take a listen here first and like always……Enjoy mes Amis
Listen: Turbosteppa – Kry Wolf & Claude VonStroke
[audio http://dl.soundowl.com/4muw.mp3]
Claude VonStroke on Facebook | Twitter | Soundcloud


text:
Posted on July 07, 2010
Brand: Loog
Save $9.00
Was: $14.00
The Loog Pick guard Set is the perfect way to protect your Loog and keep it fresh. It includes five pick guards in five different colors that are compatible with all Loog models and are easily swappable.
No reviews available.
Posted on July 07, 2010
Posted on August 30, 2010
Posted on October 26, 2010


text:
Happy Birthday Cakes Pics : Every one birthday is a very special occasion for them and others, birthday is a time when we all get together for our relationships and friendships doing surprise parties, fun, hangovers yeah. But birthday party or birthday can't fully done without cakes and their sweetness. So don't miss your friends or family members birthday and send and share with them this amazing pics of happy birthday cakes on your social networking sites like facebook, whatsapp, twitter, instagram etc.
Happy Birthday Cakes Pics For Instagram
Instagram is an online mobile photo-sharing, video-sharing, and social networking service that enables you to take pictures and videos, and share them either publicly or privately on the app, as well as through a variety of other social networking platforms, such as Facebook, Twitter, Tumblr, and Flickr.
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Facebook is a social networking site it is very easy for sending messages, sharing pics videos, making new friends from any country.
Happy Birthday Cakes Pics For Whatsapp
Whatsapp is the best mobile app for us it makes easy for sending of any music songs, audio, video, messages and status update from any where to our mobile contacts.


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chrome ball interview #98: ocean howell - Hello, my name is Ocean Howell and this is my CBI Interview. So I gotta admit that while I've always been a big fan of your skating, I honestly don't know ...
1 month ago
Jerry Gurney in Yuba City from Blood Wizard on Vimeo.
Birdhouse in Europe 2010 from Birdhouse on Vimeo.
A Happy Medium 2 Promo from Buster O'Shea on Vimeo.
Ray Barbee 20Yrs Vans from Kurt Hayashi on Vimeo.
Paul Machnau from Red Star on Vimeo.


text:
Mobile app stats
- Status Closed
- Budget $10 - $30 USD
- Total Bids 11
Project Description
Hi there,
I need someone to go through the web and find a list of amazing stats and graphs about mobile (sites & apps) users.
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Crazy Mobile Stats
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I need them copies and pasted into a word doc .. with the source.
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Not a member yet? Join now
Hi everyone,
I wanted to take B1-level Italian classes, but during the summer there don't seem to be any organized courses. Private classes are too expensive, so I thought to check if there any any other people interested in forming a group and taking group private lessons (I know Scuola Illi accomodates that).
Message me if interested!Thanks,Themis


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Have you been naughty or nice? No matter the age, this holiday child Santa vertical photo card will delight your loved ones with a cute photo, accented by candy graphics. We custom-designed this Christmas design layout to accommodate a vertical photo, although we can easily customize this design to include 1-2 horizontal photos. To include brief family updates on the back, have this custom peppermint Christmas card's design printed on flat cardstock.
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text:
Full Paper
Ring-Opening Metathesis Polymerization-based Recyclable Magnetic Acylation Reagents
Version of Record online: 20 FEB 2013
DOI: 10.1002/cssc.201200453
Copyright © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
Volume 6, Issue 4, pages 721–729, April 2013
Additional Information
How to Cite
Kainz, Q. M., Linhardt, R., Maity, P. K., Hanson, P. R. and Reiser, O. (2013), Ring-Opening Metathesis Polymerization-based Recyclable Magnetic Acylation Reagents. ChemSusChem, 6: 721–729. doi: 10.1002/cssc.201200453
Publication History
- Issue online: 8 APR 2013
- Version of Record online: 20 FEB 2013
- Manuscript Revised: 10 OCT 2012
- Manuscript Received: 29 JUN 2012
Funded by
- International Doktorandenkolleg NANOCAT
- Deutsche Forschungsgemeinschaft DFG
- EU-Atlantis program. Grant Number: CPTUSA-2006-4560
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text: Trinity Graduate School, in conjunction with Trinity College (including adult education programs REACH and Excel), offers three dual degree options: Bachelor of Arts/Master of Arts in Bioethics, Bachelor of Arts/Master of Arts in Leadership, and Bachelor of Arts in Psychology/Master of Arts in Counseling Psychology. Students can be admitted to these programs when they have completed 70 hours of undergraduate coursework, maintaining a 3.0 cumulative GPA or higher (including transfer coursework). Following admission, they may begin taking graduate courses as a part of their undergraduate course load. For students in the Bioethics, Counseling Psychology, or Leadership degrees, 9 hours of overlapping master's-level coursework allows dual degree students to finish both the BA and MA in reduced time.


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Modified conjunctivodacryocystorhinostomy for upper lacrimal system obstruction. Visualization of the inferomedial fornix (A) and blunt dissection to periosteum (B and C). The periosteum is incised with a monopolar cautery (D) and elevated using a Freer elevator down to the level of the lacrimal and maxillary bone junction (E). With the aid of a Kerrison rongeur, a bony osteotomy large enough to create a passage for the glass tube, which is inserted at a 45º angle, is performed (F). Once secured in the inferomedial fornix (G), the neck of the Pyrex tube is sutured to the adjacent conjunctiva by incorporating it in a purse string closure using a 6-0 polypropylene suture (Prolene; Ethicon Inc, Somerville, NJ) (H). Final position of the tube is at a 45º angle or more vertically, with the mouth resting in the inferomedial forniceal gutter (I).
Outcome of conjunctivodacryocystorhinostomy (CDCR) surgical procedures performed at the Jules Stein Eye Institute in January 2002 to December 2004. Thirteen cases underwent modified CDCR leaving the caruncle intact and placement of the tube in a medial incision. Seven cases underwent conventional CDCR with placement of the glass tube through a caruncle trephination. Complete success was defined as complete improvement in tearing, while partial success was defined as partial improvement. Patients who underwent modified CDCR had an overall better outcome compared with patients who underwent conventional CDCR. *P<.05 (Fisher exact test)
A, Tube position in gutter; B, displays tube position as placed intranasally. C indicates the conventional tube position; M, the modified technique with the tube more vertically placed.
Schwarcz RM, Lee S, Goldberg RA, Ben Simon GJ. Modified Conjunctivodacryocystorhinostomy for Upper Lacrimal System Obstruction. Arch Facial Plast Surg. 2007;9(2):96-100. doi:10.1001/archfaci.9.2.96
© 2017
Author Affiliations: Jules Stein Eye Institute and Department of Ophthalmology, David Geffen School of Medicine at UCLA, Los Angeles, Calif (Drs Schwarcz, Lee, and Goldberg); and Goldschleger Eye Institute, Sheba Medical Center, Tel Hashomer, Israel (Dr Ben Simon).
Correspondence: Robert M. Schwarcz, MD, Jules Stein Eye Institute, 100 Stein Plaza, Los Angeles, CA 90095 (firstname.lastname@example.com).
Objective To describe a modified technique for conjunctivodacryocystorhinostomy (CDCR) and to compare this technique with the standard transcaruncular placement of the glass tube.
Methods Patients with upper lacrimal system obstruction underwent CDCR at the Jules Stein Eye Institute during a 3-year period. Thirteen patients underwent modified CDCR leaving the caruncle intact, while 7 patients underwent Jones glass tubes placement through a caruncular incision (conventional CDCR). Data regarding ocular and tearing history were recorded and analyzed. Success rates, defined as complete improvement in tearing, were compared between patients who underwent standard CDCR and those who underwent modified CDCR. Main outcome measures included symptom relief, patients' tolerance of the Jones tube, and surgical complications.
Results Nineteen patients (12 men and 7 women; mean age, 66 years) underwent 20 CDCR surgical procedures with Jones tube placement. Previous lacrimal history included malignancy of the ocular adnexa, trauma, chemotherapy, and previous failed dacryocystorhinostomy. Success was found in 13 surgical cases (65%) and partial improvement was found in 4, giving a qualified success rate of 85%. Patients who underwent modified CDCR were more likely to undergo a successful surgery compared with patients who underwent conventional CDCR, with 11 (85%) of 13 cases achieving complete improvement vs 2 (29%) of 7 cases in the conventional CDCR group (P = .03, Fisher exact test). Complications included 1 case of migration and loss of the Jones tube.
Conclusion Modified CDCR results in partial or complete resolution of tearing in nearly 92% of cases, allowing for an improved outcome both functionally and cosmetically compared with conventional CDCR.
Conjunctivodacryocystorhinostomy (CDCR) with Jones tube placement is generally performed to bypass the lacrimal canaliculi and sac, providing a direct route for tears to enter the nasal cavity in cases of upper system blockage. In 1962, Lester Jones1 first described this procedure for nonreconstructable lacrimal canalicular obstruction. A glass Pyrex tube is inserted into the new communication created, and between the actions of the tear pump and the capillary pull of the tube, tears are drained into the nasal cavity without the aid of the nasolacrimal system.1-3
The standard external CDCR approach as described by Jones2 used an external skin incision to create the bony osteotomy, then after being introduced by a large bore needle, the Pyrex tube was passed through the medial canthal angle. Several years ago, Trotter and Meyer4 described an endoscopic approach to this surgery that allows the placement of this bypass tract without the need for a skin incision. We describe a technique that involves no skin incision and no endoscope and a more anatomical placement of the Pyrex tube.
Data regarding all patients diagnosed as having upper lacrimal system obstruction in the ophthalmic plastic service at the Jules Stein Eye Institute, Los Angeles, Calif, between January 2002 to December 2004, who underwent conjunctivodacryocystorhinostomy (CDCR), were recorded and analyzed (retrospective medical chart review). All patients with tearing secondary to upper canalicular obstruction who underwent CDCR were included. Complete success was defined as complete improvement in tearing. Success was considered only with good position of the Jones tube in the nose and no patient discomfort associated with postoperative care. The study was approved by the local institutional review board. Informed consent was obtained prior to surgery.
Statistical analysis was performed using the paired samples t test to evaluate preinjection and postinjection data such as visual acuity. The χ2 and Fisher exact nonparametric tests were used to evaluate outcome and to compare success rates between the 2 techniques. Statistical analysis was carried out with Microsoft Excel XP (Microsoft Corporation, Redmond, Wash) and SPSS software (SPSS Inc, Chicago, Ill).
Under monitored anesthesia care, patients are preoperatively given nasal packing soaked with 4% cocaine, which is carefully placed under the middle turbinate. The packing is removed, and the middle turbinate, inferior conjunctival fornix, and medial canthal angle are all infiltrated with 2% lidocaine with 1:100 000 epinephrine.
The surgical assistant exposes the area of the inferomedial conjunctival fornix inferolateral to the caruncle with a lacrimal rake and 0.5-mm Castroviejo forceps (Figure 1A). With the aid of Stevens tenotomy scissors, blunt dissection is carried down to the level of the periosteum overlying the lacrimal and maxillary bone junction (Figure 1B and C). The periosteum is incised with a monopolar cautery and elevated anteriorly with a freer elevator (Figure 1D and E). The exposed bone is then infractured with the tip of the freer elevator, and a Kerrison rongeur is used to create a bony osteotomy large enough to create a passage for the glass tube, which is inserted at a 45º angle. Included in this dissection is the underlying nasal mucosa (Figure 1F). A Bowman probe is placed through the conjunctival opening and viewed intranasally to estimate the proper length of the tube needed. Under direct visualization with the aid of a nasal speculum or endoscope, the tube is placed through the conjunctival incision into the anterior nasal cavity in an inferomedial vector, with reconstruction of the nasal septum or middle turbinate when necessary. Once secured in the inferomedial fornix, the neck of the Pyrex tube is sutured to the adjacent conjunctiva by incorporating it in a purse string closure (Figure 1G and H). The final position of the tube is placed at a 45º angle or more vertically, with the mouth resting in the inferomedial fornix and the tip extending 2 to 5 mm into the nasal cavity (Figure 1I).
Conventional CDCR is performed in a similar fashion but with the Jones tube placed through the caruncle using a Hendersen trephine and placing the tube at a 30º angle or more horizontally.
Nineteen patients (12 men and 7 women; mean age, 66 years) underwent 20 CDCR surgical procedures with Jones tube placement. Thirteen patients (65%) underwent modified CDCR leaving the caruncle intact, while 7 patients (35%) underwent conventional CDCR. Demographics of the study population and surgical outcome are summarized in the Table.
Lacrimal history included malignancy of the ocular adnexa, trauma, chemotherapy, and previous failed dacryocystorhinostomy (Table). The mean tube length for the modified approach was 18 mm, with a mean diameter of 3.8 mm. The tube was sutured in 9 cases (45%) using polypropylene (6 patients) or polyglactin 910 (Vicryl; Ethicon, Inc, Piscataway, NJ) sutures (2 patients).
The surgical outcome was favorable in most cases, with 13 patients (65%) reporting complete improvement in tearing and 4 patients (20%) reporting partial improvement, giving a qualified success rate of 85%. Patients who underwent fornix-based CDCR had a higher success rate compared with patients who underwent canthal-based CDCR. Of the 13 patients in the modified CDCR group, 11 (85%) reported complete improvement in tearing and 1 (8%) reported partial improvement in tearing. Of the 7 cases in the conventional CDCR group, the corresponding values were 2 (29%) and 3 (43%) for complete and partial success, respectively. This difference was statistically significant (P = .04, Fisher exact test) (Figure 2).
Visual acuity did not change after surgery (delta logMAR [logarithm of the minimum angle of resolution] visual acuity of 0.025; P = .40, 1-sample t test).
Complications included 1 case of tube migration and scarring of the fistula tract. The patient did not undergo additional surgical procedures. One patient who underwent conventional CDCR also underwent successful surgery revision and placement of the tube medial to the caruncle (modified CDCR). Of the 3 failed cases, 2 involved operations on patients with histories of nasopharyngeal carcinoma. Of note, these 2 patients underwent extensive surgery including ethmoidectomy, septectomy, and radiation prior to CDCR; these 2 patients underwent canthal-based CDCR. In the third failed case, inappropriate position of the tube with globe irritation was noted, but the patient did not undergo additional revision.
Lacrimal canalicular bypass tract surgery, first described by Lester Jones,1 is indicated for epiphora secondary to obstruction at the level of the canliculi.5 Lim et al6 recently reported a patient dissatisfaction rate of 30%, with persistence of overflow tearing while patients were recumbent and patient dissatisfaction with aesthetic outcome. They also reported complications of tube malposition, obstruction, and extrusion.6
The literature provides several variations modifying the Jones tube as originally described for canalicular obstruction. In some surgical variations, a skin incision is used, but we have not found a cutaneous incision necessary to achieve adequate osteotomy and tube placement.
We describe a modified technique for placement of the Jones tube in a more anatomic position. Placing the tube in the inferomedial conjunctival fornix positioned vertically, rather than the standard canthal-based transcaruncular route positioned horizontally (Figure 3), places the mouth of the tube directly in the lacrimal lake. A more inferomedial placed and directed Jones tube allows for better cosmesis, hiding the mouth of the tube under cover of the medial eyelid. The vertical position of the tube often allows more room to position the tip in the nasal cavity, provides a longer soft tissue passage for stability (Figure 3) (whether or not frosted or shaped tubes are used for better fixation), and may allow better drainage action by gravity on the fluid within the tube lumen. The mouth of the tube is generally better hidden cosmetically, as opposed to its visible status in the place of the caruncle.
Abel and Meyer7 reported cases of refractory conjunctival inflammation in cases without caruncletomies. Liu8 described a conjunctival incision for Jones tube placement allowing for no skin incision or endoscopy, as we describe, but he performs a carunclectomy and places the tube in a less inferior vector.
The nuances of Jones tube positioning and placement are unlikely to dramatically affect the outcome, and our results emphasize the relatively good outcome of both techniques. Although this study was limited by its retrospective nature and relatively small number of patients, we noted a statistically significant improvement in success rate in patients with a fornix-based tube, supporting our anecdotal impression. A prospective randomized study would obviously better define the outcomes of various Jones tube techniques. Lacking that type of data, the surgeon should consider the different anatomic options for Jones tube placement in light of his or her own experience and the patient's individual anatomy. We suggest that vertical orientation of the tube, with the mouth in the medial fornix, is an appropriately considered option that may have potential advantages.
Accepted for Publication: November 9, 2006.
Author Contributions:Study concept and design: Schwarcz and Goldberg. Acquisition of data: Lee. Analysis and interpretation of data: Ben Simon. Drafting of the manuscript: Schwarcz and Lee. Critical revision of the manuscript for important intellectual content: Schwarcz, Goldberg, and Ben Simon. Statistical analysis: Ben Simon. Administrative, technical, and material support: Schwarcz and Lee.
Financial Disclosure: None reported.


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NASA satellite nears its rendezvous with Jupiter
LOS ANGELES – Jupiter takes center stage with the arrival next week of a
The solar-powered Juno spacecraft is on the final leg of a five-year, 1.8 billion-mile voyage to the biggest planet in the solar system.
Juno promises to send back the best close-up views as it circles the planet for a year. Jupiter is a gas giant made up mostly of hydrogen and helium, unlike rocky Earth and its neighbor Mars. The fifth planet from the sun likely formed first, and it could hold clues to how the solar system developed.The arrival
As Juno approaches Jupiter late Monday, it will fire its main rocket engine to slow down and slip into orbit around the planet. This carefully orchestrated move, all preprogrammed, is critical because Juno will zip past Jupiter if it fails to brake. The engine burn – lasting about half an hour – is designed to put Juno on a path that loops over Jupiter's poles.
Because it takes 48 minutes for radio signals from Jupiter to reach Earth, mission controllers at NASA's Jet Propulsion Laboratory in Southern California won't be able to intervene if something goes awry.The mission
Juno will peer through dense clouds, flying within 3,100 miles, closer than any other spacecraft.
The goal "is learning about the recipe for how solar systems are made," said Juno chief scientist Scott Bolton.The pictures
The Hubble Space Telescope and other spacecraft have returned stunning pictures of Jupiter, including a new photo released Thursday of its northern lights. But scientists said the best views are yet to come. Juno will get in closer and will provide the most detailed look at the planet's polar regions, clouds and auroras.
The camera onboard – the JunoCam – has been snapping pictures of Earth, Jupiter and its moons along the way. But the camera and other instruments were turned off this week to avoid any interference during the critical arrival. So there won't be images at the nail-biting moment when Juno enters orbit.
The public can vote on where to point the camera. NASA has said pictures from the mission won't be publicly released until at least late August.
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I have been told that general surgeon would be fine but i just recently had 2 strokes and am concerned about anesthesia
Should a Plastic Surgeon Remove Non-encapsulated Infiltrating Lipoma in Deltoid Muscle?
Doctor Answers 2
Choosing a lipoma surgeon
Regardless of whether you have a general surgeon or a plastic surgeon, you will need anesthesia to remove the lipoma. So anesthesia is not a deciding point.
These answers are for educational purposes and should not be relied upon as a substitute for medical advice you may receive from your physician. If you have a medical emergency, please call 911. These answers do not constitute or initiate a patient/doctor relationship.


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Uniform systems of communicating extended finite-state automata are considered. These systems can be used for the initial specification of telecommunication systems such as ring protocols and telephone networks. This paper aims to present an automata systems verifier tool (ASV) designed for the analysis and verification of automata specifications. It is… (More)
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