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Synthesis, characterization, biodistribution and scintigraphy of 99mTc-paclitaxel: a potential tracer of paclitaxel
Banerjee I.,CSIR - Central Electrochemical Research Institute |
Behera A.,CSIR - Central Electrochemical Research Institute |
De K.,CSIR - Central Electrochemical Research Institute |
Chattopadhyay S.,Variable Energy Cyclotron Center |
And 4 more authors.
Journal of Radioanalytical and Nuclear Chemistry | Year: 2015
99mTc-paclitaxel was synthesized by using sodium borohydride as a reducing agent. Greater than 95 % labelling efficiency was achieved. Radiochemical purity of the synthesized 99mTc-paclitaxel was validated by thin layer chromatography (TLC) scanner and high performance liquid chromatography (HPLC). 99mTc-paclitaxel passed in vitro stability tests. Biodistribution and scintigraphy studies were performed in Sprague–Dawley rats. The biodistribution study results of 99mTc-paclitaxel were related mainly to the metabolism and excretion routes followed by the parental drug, paclitaxel. Apart from that, biodistribution of 99mTc-paclitaxel was altered after pre-treatment with cold paclitaxel. Hence, 99mTc-paclitaxel may be used as a tracer for paclitaxel. © 2014, Akadémiai Kiadó, Budapest, Hungary. Source
Paclitaxel-loaded solid lipid nanoparticles modified with Tyr-3-octreotide for enhanced anti-angiogenic and anti-glioma therapy
Banerjee I.,CSIR - Central Electrochemical Research Institute |
De K.,CSIR - Central Electrochemical Research Institute |
Mukherjee D.,CSIR - Central Electrochemical Research Institute |
Dey G.,Indian Institute of Technology Kharagpur |
And 7 more authors.
Acta Biomaterialia | Year: 2016
Somatostatin receptors (SSTRs) especially subtype 2 (SSTR2) are overexpressed in glioma. By taking advantage of the specific expression of SSTR2 on both glioma neovasculature endothelial cells and glioma cells, we constructed Tyr-3-octreotide (TOC)-modified solid lipid nanoparticles (SLN) loaded with paclitaxel (PTX) to enable tumor neovasculature and tumor cells dual-targeting chemotherapy. In this work, a TOC-polyethylene glycol-lipid (TOC-PEG-lipid) was successfully synthesized and used as a targeting molecule to enhance anticancer efficacy of PTX loaded sterically stabilized lipid nanoparticles. The prepared PTX-loaded SLN modified with TOC (PSM) was characterized by standard methods. In rat C6 glioma cells, PSM improved PTX induced apoptosis. Both tube formation assay and CD31 staining of treated orthotopic glioma tissues confirmed that PSM significantly improved the antiangiogenic ability of PTX in vitro and in vivo, respectively. Radiolabelled PSM achieved a much higher and specific accumulation within the glioma as suggested by the biodistribution and imaging studies. Furthermore, PSM exhibited improved anti-glioma efficacy over unmodified nanoparticles and Taxol in both subcutaneous and orthotopic tumor models. These findings collectively indicate that PSM holds great potential in improving the efficacy of anti-glioma therapy. Statement of Significance Somatostatin receptors (SSTRs) especially subtype 2 (SSTR2) are overexpressed in various mammalian cancer cells. Proliferating endothelial cells of neovasculature also express SSTR2. Tyr-3-octreotide (TOC) is a known ligand for SSTR2. We have successfully prepared paclitaxel-loaded solid lipid nanoparticles modified with TOC (PSM) having diameter less than 100 nm. We found that PSM improved anti-cancer efficacy of paclitaxel in SSTR2 positive glioma of rats. This improved anti-glioma efficiency of PSM can be attributed to dual-targeting (i.e. tumor cell and neovasculature targeting) efficiency of PSM and promoted anti-cancer drug accumulation at tumor site due to TOC modification of solid lipid nanoparticles. This particular study aims at widening the scope of octreotide-derivative modified nanocarrier by exploring dual-targeting potential of PSM. © 2016 Acta Materialia Inc. Source
Synthesis and evaluation of technetium-99m-labeled bioreductive pharmacophores conjugated with amino acids and peptides for tumor imaging
Baishya R.,CSIR - Central Electrochemical Research Institute |
Nayak D.K.,CSIR - Central Electrochemical Research Institute |
Karmakar S.,Jadavpur University |
Chattopadhyay S.,Variable Energy Cyclotron Center |
And 4 more authors.
Chemical Biology and Drug Design | Year: 2015
Development of molecular imaging agents to target tumor has become a major trend in nuclear medicine. With the aim to develop new potential 99mTc-radiopharmaceuticals for targeting tumor, we have synthesized 5-nitroimidazolyl amino acids and RGD-coupled 2-nitroimidazoles. Technetium-99m radiolabeling with high radiochemical purity (>90%) was achieved for all the compounds. The radiolabeled complexes exhibited substantial in vitro stability in saline, serum, and histidine solution (10-2 m). Cell binding studies in EAC and B16F10 cell lines also revealed rapid and comparatively high cellular internalization. Among all the compounds studied, the binding of 99mTc(CO)3-5 to B16F10 cells was moderately inhibited by the competitive peptide c[RGDfV], suggesting specificity of the radioligand toward αvβ3 receptor. However, no significant displacement of bound radioligand was observed when the binding of the 99mTc-labeled complexes to above cells was challenged with excess competitive peptide. Fluorescent microscopy study provided direct evidence of intracellular localization of 5(6)-carboxyfluorescein-labeled 2-nitroimidazolyl-RGD-peptide in αvβ3-positive B16F10 mouse melanoma cell line. The ligands caused only 8-13% of hemolysis toward rat erythrocytes at concentrations as high as 100 μm. Imaging and biodistribution studies were performed in Swiss albino mice bearing induced tumor. 99mTc-1 and 99mTc(CO)3-5 demonstrated a very favorable in vivo profile. Selective uptake and retention in tumor with encouraging tumor/muscle and tumor/blood ratio and significant cellular uptake of fluorescence-labeled-2-nitroimidazolyl RGD indicate the great potentiality of the pharmacophore for further evaluation as potential molecular imaging agent in cancer diagnosis. © 2014 John Wiley & Sons A/S. Source
Nayak D.K.,CSIR - Central Electrochemical Research Institute |
Baishya R.,CSIR - Central Electrochemical Research Institute |
Halder K.K.,CSIR - Central Electrochemical Research Institute |
Sen T.,Jadavpur University |
And 4 more authors.
Metallomics | Year: 2012
The aim of this study was to develop 99mTc(CO) 3-labeled fluoroquinolones as novel SPECT radiopharmaceuticals for imaging bacterial infection. Fluoroquinolones, e.g., ofloxacin (OFX), levofloxacin (LVX), lomefloxacin (LMX) and norfloxacin (NFX) were labeled with a fac-[99mTc(CO)3(H2O)3]+ precursor. The radiochemical purity of the radiopharmaceuticals exceeded 97% as determined by thin layer chromatography and HPLC. No further purification was necessary before injection. The Re(CO)3 complex of one of the fluoroquinolones (levofloxacin) was synthesized using [Re(CO)3(H 2O)3]OTf and Re(CO)5Br precursors in separate experiments and characterized by IR, NMR and mass spectroscopic analysis. These studies revealed the formation of a single species in which the piperazinyl nitrogen and the -COOH group attached to the benzoxazine ring system of quinolone were involved in co-ordination to the Re(CO)3 core. The HPLC elution pattern and retention time of the Re(CO)3-LVX complex were comparable to those of the corresponding 99mTc(CO) 3-complex proving their similarity. When incubated in isotonic saline and serum up to 24 h 99mTc(CO)3-labeled fluoroquinolones exhibited good in vitro stability. Biodistribution studies performed at different time points on rats intramuscularly infected with S. aureus as well as on rats with sterile inflammation revealed a higher uptake in the infected area than the turpentine induced inflamed area. The uptake in infected thigh was significant with 99mTc(CO)3-OFX followed by 99mTc(CO)3-LVX. The mean ratios of the uptake in infected/non-infected thighs were 4.75 and 4.27 at 8 h and 24 h, respectively, for 99mTc(CO)3-OFX and 4.42 and 4.18 at 24 h and 8 h, respectively, for 99mTc(CO)3-LVX. The above abscess to muscle ratios were higher than reported for 99mTc-ciprofloxacin and other 99mTc-labeled fluoroquinolones. Scintigraphy studies also showed a significant uptake in the infectious lesions suggesting that 99mTc(CO)3-fluoroquinolones might be useful as diagnostic agents for targeted delivery in bacterial infection. This journal is © The Royal Society of Chemistry 2012. Source
Synthesis, characterization, conformational analysis of a cyclic conjugated octreotate peptide and biological evaluation of 99mTc-HYNIC-His 3-Octreotate as novel tracer for the imaging of somatostatin receptor-positive tumors
Behera A.,Indian Institute of Science |
Banerjee I.,Indian Institute of Science |
De K.,Indian Institute of Science |
Munda R.N.,Indian Institute of Science |
And 5 more authors.
Amino Acids | Year: 2013
Peptides are attracting increasing interest in nuclear oncology for targeted tumor diagnosis and therapy. We therefore synthesized new cyclic octapeptides conjugated with HYNIC by Fmoc solid-phase peptide synthesis. These were purified and analyzed by RP-HPLC, MALDI mass, 1H NMR, 13C NMR, HSQC, HMBC, COSY and IR spectroscopy. Conformational analysis of the peptides was performed by circular dichroism spectroscopy, in pure water and trifluoroethanol-water (1:1), revealed the presence of strong secondary structural features like β-sheet and random coils. Labeling was performed with 99mTc using Tricine and EDDA as coligands by SnCl 2 method to get products with excellent radiochemical purity >99.5 %. Metabolic stability analysis did not show any evidence of breaking of the labeled compounds and formation of free 99mTc. Internalization studies were done and IC50 values were determined in somatostatin receptor-expressing C6 glioma cell line and rat brain cortex membrane, and the results compared with HYNIC-TOC as standard. The IC50 values of 99mTc-HYNIC-His3-Octreotate (21 ± 0.93 nM) and 99mTc-HYNIC-TOC (2.87 ± 0.41 nM) proved to be comparable. Biodistribution and image study on normal rat under gamma camera showed very high uptake in kidney and urine, indicating kidney as primary organ for metabolism and route of excretion. Biodistribution and image study on rats bearing C6 glioma tumor found high uptake in tumor (1.27 ± 0.15) and pancreas (1.71 ± 0.03). Using these findings, new derivatives can be prepared to develop 99mTc radiopharmaceuticals for imaging somatostatin receptor-positive tumors. © 2012 Springer-Verlag Wien. Source


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VQSpot for VQLog
VQSpot is a simple utility program developed for sending DX-Spots automatically when QSO are logged into VQLog
Listed in Software/DX Cluster
[ Hits: 449 | Votes: 1 | Rating: 1.00 ]
About VQSpot for VQLogThe "VQSpot for VQLog" resource is listed in dxzone.com under 2 categories. Its main category is DX Cluster client software (Ham Radio DX Cluster clients). Listed in our web site directory since Thursday May 7 2009, as a result, till today this link has been followed 449 times. So far received 1 votes for a total score of 1.00/10
In addition to this page, you will find "VQSpot for VQLog" probably along to other similar resources, listed under the following categories:
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412 Evergreen St,San Antonio TX, 78212
Sold Price
3 beds , 1 Full baths
1,340 sq. ft
Status: Sold
Berkshire Hathaway HomeServices Don Johnson, REALTORS
(210) 493-1766
Last Updated: 2/26/2017 6:03 PM
Description for 412 Evergreen St San Antonio, TX 78212
Trendy remodeled 3 bedroom, 1 bath home in the highly desired area of Tobin Hill! NO CARPET! NEW laminate floors & tile throughout the home, ceiling fans, cozy fireplace and new kitchen cabinets! This charming home is conveniently located near San Antonio College, Baptist Memorial Hospital and Downtown! NEW DECK is being added the first week of November! Schedule your showing today!
Listing Information
Tobin Hill
School Information
Room Information
Full Bath
Interior Features
Central Air, Ceiling Fan(s)
Electric Heating, Central
High Ceiling
Exterior / Lot Features
2 Garage Spaces, Side Entry
Wood Shingle
No Pool
Financial Considerations
Inside AccessTM
Current market conditions for 412 Evergreen St
Active Market Trends
Source:MLS DATA
Median list price$245,000
Days on market92
Properties for sale4,676
Sold Market Trends
Source:MLS DATA
Median sold price$185,000
Sales to list price9,776.0%
Properties sold4,068
Median sq ft price$100
Arrows indicate 90 day trend
Listing Price History for 412 Evergreen St
San Antonio Real Estate
San Antonio is located in Texas. San Antonio, Texas 78212 has a population of 1,335,287.
The median household income in San Antonio, Texas 78212 is $44,937. The median household income for the surrounding county is $49,141 compared to the national median of $53,046. The median age of people living in San Antonio 78212 is 32.7 years.
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Today, my jeans got caught in the airport escalators. Seeing as how we couldn't get them unstuck, my mother made me take them off. FML
Today, I sneezed after watching a commercial involving dust. FML
Today, my alcoholic mother decided to finally check herself into rehab. She did it while drunk, and flirted with the front attendant. FML
Today, I had a package stolen from my porch. It was a shipment of customized M and M's for a Valentine's gift. I spent $60 for someone else to eat "I love you" messages. FML
Today, I walked into the house only to be greeted by the strongest smell of dung. I asked my mom about it, and it turns out she's been airing these strange herbs throughout the house, most of which are in my bedroom. She won't let me open the window. FML
Today, I was called an 'unhelpful little bitch' by a customer, after I informed her that we couldn't order a pair of shoes she wanted from the company in her size because it's a discontinued model. This little tirade continued for another few minutes, with her insulting me and my intelligence. FML
Today, I made a Sim of myself and had her work out until she was completely fit, then got her a job and a husband. Meanwhile, I sat at my desk, fat, single and jobless. FML
Today, I was dumped. My boyfriend was too afraid to break up with me, so he sent the girl he cheated on me with. FML
Today, my girlfriend openly mocked me, calling me an idiot for thinking seahorses are real. She insists that they're like unicorns, and only exist in fiction. FML
Today, while I was standing in line at the store, some guy insulted the girl in front of me as he walked past. She turned around and socked me in the face. FML


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About PRSSA
Both PRSA and PRSSA are committed to the letter and spirit of the law regarding accessibility of our program to individuals with disabilities. If you have any special need(s), please contact us as far in advance of the program as practicable so that we may address your request.
© 2010–17 The Public Relations Society of America, Inc., 120 Wall Street, 21st Fl., New York, NY 10005-4024


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Tiffany Industries Corsica Series Credenza, 72w x 20d x 29-1/2h, Sierra CherryDesk Shells
Hardwood veneer credenza with full-height modesty panel. - View Complete Details
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Tiffany Industries Corsica Series Credenza, 72w x 20d x 29-1/2h, Sierra Cherry - Italian-influenced style adds sophistication to executive settings. AA-grade select hardwood veneers throughout with 14-step finishing process provides consistent beauty and uncompromised quality. Worksurface is protected with two final coats of high-tech catalyzed lacquer for durability and hardness. Full-size end panels and full-height modesty panel. Beveled black edge detail.View Product Specs
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Little Asia: "Vietnamese Food" Little Asia Tip by Suet
Little Asia, Brussels: 2 reviews and 2 photos
YUMMM!!!! The food was fantastic.... I felt the decor was a little sparse however, minimalist to the extreme but it was warm enough *temp wise* and very very very good food.
We had Nems to start 6.00 euros each, then chicken in cashews nuts and a beef dish at 12.00 euros each *including rice* so the food came to a total of 36.00 for two. Add the drinks (oopsy) and you get a total of 54.50.... service not included.
Favorite Dish: I must admit the nems *small fried parcels of veggies served with a sauce* are very good indeed. A nice starter. I have had them all over the world and they never fail to be tasty.
Address: 8 Rue St Catherine 1000 Bruxelles
Price Comparison: about average
Directions: dunno you'll have to look at the map!!!
Phone: 02 502 88 36
Price: US$41 and up
Rating: 5
Theme: Pan-Asian and Pacific Rim
Website: http://littleasia.be/?lang=en
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- Product J12836
Peavey Versarray 218 Subwoofer
- Write a Review
An incredible 4,800-watt program rating is made possible by Kevlar-impregnated cones that increase strength and minimize distortion, as well as polym...Click To Read More About This Product
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Find a similar product below or contact our experts for a recommendation of great alternatives. Call us at 800-449-9128.Customers Also Viewed:
18" sub, with a heavy low end.
An incredible 4,800-watt program rating is made possible by Kevlar-impregnated cones that increase strength and minimize distortion, as well as polymide-impregnated fiberglass formers, die-cast aluminum frames and 4" diameter edge-wound voice coils with solderless, diffusion-welded OFHC copper leads. The Versarray 218 also features the Peavey UniVent venting system (U.S. Patent #6,549,637), which uses an exclusive process to literally pump cool outside air through the enclosure, maintaining cool operating temperatures, increasing reliability and reducing power compression under heavy continuous-drive conditions. With premium 13-ply Baltic birch construction, a durable acrylic polyurethane finish and a 16-gauge, powder-coated perforated metal grille, the Versarray 218 is built to endure years of heavy use, and tilt-back 4" casters allow easy transport and setup along the way. Input connections are made via two 4-pin Neutrik jacks in parallel, or an 8-pin Neutrik with a 4-pin Neutrik thru jack for bi-amping. An optional bolt-on Ground Stack Kit allows users to mount up to three Versarray 112 enclosures with full articulation.
A two-time veteran of the Rockstar Mayhem Festival, the Versarray 212 line array offers extreme versatility in the most demanding sound-reinforcement applications. This three-way enclosure is outfitted with two 12" Black Widow woofers, ten midrange drivers and four planar ribbon drivers mounted to a manifold line source that enables critically damped operation with immediate transient response. All 16 components utilize neodymium magnets that yield lighter weight and greater efficiency over traditional magnet designs.
Any line array claiming true versatility should be able to excel in any application you can throw its way. That's what makes the Versarray 112 so unique - it holds its own nightly in world-class venues like Ground Zero Blues Club, the juke joint co-owned by Morgan Freeman, and has whipped up crowds at outdoor music festivals like Ozzfest and the New Orleans Jazz & Heritage Festival. The Versarray 112 utilizes a high-performance, lightweight 12" Neo Black Widow woofer and dual ribbon drivers.
Designed for use with Versarray line arrays, the Versarray 118 and 218 subwoofers incorporate Peavey's ultra-high power Lo Max 18" woofer into a 13-ply Baltic birch cabinet. The 2x18 model also features Peavey's patented UniVent venting system, which uses an exclusive design to literally pump air through the enclosure, maintaining cool operating temperatures, increasing reliability and reducing power compression under heavy continuous-drive conditions.
The Versarray system allows maximum articulation from each enclosure with Peavey's exclusive bracket-and-pin flying hardware. This highly flexible rigging system gives users a multitude of array possibilities, from traditional flying to ground stacking or pole mounting. Versarray accessory packages include everything you need to achieve perfect sound, from locking pins and fly bars to a crankable speaker lift.
- Power Handling: 2400 watts continuous, 4800 watts program
- Frequency Response: 45Hz to 1.5kHz (anechoic environment)
- Full-power low-frequency response down to 38Hz
- Two 18" vented Lo Max woofers
- 4/8 ohms selectable
- 9600 watts peak
- One Neutrik 8-pin Speakon input
- One Neutrik 4-pin Speakon thru imput (use with 8-pin input)
- Patented UniVent vented cooling system (U.S. Patent #6,549,637)
- Durable GatorHyde finish
- Made in the U.S.A.
Start creating your own Versarray Line Array system today!
Versarray 218 Subwoofer
- Weight Unpacked: 200.00 lb. (90.72 kg)
Weight Packed: 215.00 lb. (97.524 kg)
Width Packed: 28.5" (72.39 cm)
Height Packed: 45" (114.3 cm)
Depth Packed: 28.5" (72.39 cm)


text: Release of some raghead fanatic British law can surely kiss its arse goodbye. Laughable that this man is now allowed to be in public. Bin Laden's man in Europe is now a free man. This cannot be right. And frankly is a blight on the men and women who are trying to free the people this idiot is trying to poison and turn against us.


text:
Welcome to the CLEAA Website
As the major association for practitioners involved in the provision of continuing legal education and professional development to the legal profession, CLEAA provides ongoing information and opportunities for discussion to members on current issues.
CLEAA circulates a quarterly e-newsletter to facilitate information sharing and communication, and posting papers and key items of interest to the CLEAA Website.
The CLEAA Executive also look forward to meeting members and participants in the provision of legal education and professional development at our annual conference together with a range of State events planned during 2016/17.
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Save the Date: CLEAA 2017 Annual Conference: 12 October College of Law Level 16, St James Centre 111 Elizabeth Street Sydney NSW 2000 More details coming soon…
04.10.2016Jan Christie's evidence presented at the Law Society of NSW's hearing on the future of the Profession
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|We could ultimately develop sound to the point where people ask for talking pictures
– H.M. Warner, Warner Brothers, 1927.Rate it:
|We create an environment where it is alright to hate, to steal, to cheat, and to lie if we dress it up with symbols of respectability, dignity and love.
– Whitney Moore, Jr.Rate it:
|We create history by our act and deeds.
– Amenorhu kwakuRate it:
|We create in people through our actions and example. In this way people around us become reflections of our own behavioral patterns and internal energies.
– Bryant McGillRate it:
|We create our lives a thought at a time. And sometimes, it comes down to changing a thought such as 'Why did this happen to me' into 'There is a divine plan and there is a reason for this, and my choice is to create the most positive reaction I can.'
– Dee Wallace StoneRate it:
|We cross our bridges when we come to them and burn them behind us, with nothing to show for our progress except a memory of the smell of smoke, and a presumption that once our eyes watered.
– Tom StoppardRate it:
|We dance in a circle and suppose, while the secret sits in the middle and knows.
– Robert FrostRate it:
|We dare not tempt them with weakness. For only when our arms are sufficient beyond doubt can we be certain beyond doubt that they will never be employed.
– John Fitzgerald KennedyRate it:
|We deceive ourselves when we fancy that only weakness needs support. Strength needs it far more.
– Madame SwetchineRate it:
|We deliberate about the parcels of life, but not about life itself, and so we arrive all unawares at its different epochs, and have the trouble of beginning all again. And so finally it is that we do not walk as men confidently towards death, but let death come suddenly upon us.
– SenecaRate it:
|We delight in the beauty of the butterfly, but rarely admit the changes it has gone through to achieve that beauty.
– Maya AngelouRate it:
|We demand privacy, yet we glorify those that break into computers.
– Bill McCollumRate it:
|We derive our vitality from our store of madness.
– Emil CioranRate it:
|We desire nothing so much as what we ought not to have.
– Publilius SyrusRate it:
|We determine our own price; it is always good to set our price to infinity so that no one can buy us!
– Mehmet Murat ildanRate it:
|We did not change as we grew older we just became more clearly ourselves.
– Lynn HallRate it:
|We did not change as we grew older; we just became more clearly ourselves.
– Lynn Hall, Where Have All the Tigers Gone?, 1989Rate it:
|We did not join this government to establish a Palestinian state, but to stop this terrible idea - our position is clear to the prime minister and we believe that it is his position as well. We are reminding him that there are domestic coalition agreements that take priority over international pressure. We are opposed to the two-state solution. We believe it is not a solution – it is the start of a problem and it makes existing problems worse.
– Uri OrbachRate it:
|We die with a notice. Notice, this is our life. (Nous mourons avec un préavis. Le préavis, c'est notre vie)
– Charles de LEUSSERate it:
|We discovered that peace at any price is no peace at all.
– Eve Denise CurieRate it:
|We dissect nature along lines laid down by our native language. Language is not simply a reporting device for experience but a defining framework for it.
– Benjamin Lee WhorfRate it:
|We distinguish the excellent man from the common man by saying that the former is the one who makes great demands upon himself, and the latter who makes no demands on himself.
– Jose Ortega y GassetRate it:
|We do not attract what we want, But what we are.
– James AllenRate it:
|We do not believe in immortality because we can prove it, but we try to prove it because we cannot help believing it.
– Harriet MartineauRate it:
|We do not condemn the preachers as an individual but we condemn what they teach. We urge that the preachers teach the truth, to teach our people the one important guiding rule of conduct -- unity of purpose.
– Malcolm XRate it:


text:
Based on the popular British program, Top Gear Australia looks to give a unique Aussie spin on the car scene while still having all thrills and spills that we all love. Plus there is the Stig's Australian cousin. What more could we ask for!
Top Gear Australia
February 4, 2016


text:
Schumacher's health remains private matter
The condition of Michael Schumacher's health will remain closely guarded among family and close associates, the former Formula One champion's manager said on Saturday.
"Michael's health is not a public issue, and so we will continue to make no comment in that regard," Sabine Kehm said in a statement.
"We have to protect his intimate sphere. Legally seen and in the longer term, every statement related to his health would diminish the extent of his intimate sphere."
Schumacher sustained severe head injuries in a skiing accident in France on December 29, 2013 and has been cared for at his home in Switzerland since September 2014.
Kehm said the Schumacher family was aware that fans were hoping for news of the 47-year-old German's condition, "but we do this with full commitment to Michael's guidelines and can only thank people for their understanding."
Kehm announced that the family was launching a "Keep Fighting Initiative" as a sign of gratitude to fans and to encourage people inspired by Schumacher's career "to keep fighting and never give up."
Schumacher's accident happened on a family vacation as he was skiing with his son at the Meribel ski resort in the French Alps. The avid skier hit the right side of his head on a rock, cracking his helmet. Doctors operated to remove blood clots from his brain, but some were left because they were too deeply embedded.
Schumacher's condition stabilised after he was placed in a drug-induced coma, from which he later emerged.
"Michael has always been very protective of his privacy, even during the most successful times of his career. He has always made sure there is a clear and distinct line between his public persona and his private one," Kehm said.
Schumacher, who made his name with Benetton before joining Ferrari in 1996, won a record seven F1 titles and 91 races.
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Trump wants to expand US nuclear arsenalReuters
Nerve agent used in murder of Kim Jong NamReuters


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- College Overview
- Dean's Welcome
- Mission and Tradition
- Diversity, Equity, and Inclusion
- Expect Respect
- Administration
- Amazing Facilities
- Maps
- Contact Us
Preface: A Note on the LSA DEI Plan
The College of Literature, Science and the Arts is pleased to participate in the campus wide diversity, equity, and inclusion planning process. Hundreds of faculty, students, and staff have already contributed to the LSA plan and we encourage further engagement across the College community.
Our feedback email—email@example.com—was sent, along with the full draft of our plan, to more than 20,000 members of the LSA community in August. It remains open to those who have yet to send us their ideas, comments, criticisms and editorial suggestions.
We have already begun implementing many of the elements of this plan, several of which have already been completed. Those already underway include:
Calling for applications to the first cohort of the LSA Collegiate Postdoctoral Fellowship Program, which aims to recruit a total of 50 fellows and convert these positions to tenure track lines upon successful completion of the two-year fellowship.
Implementing recommendations from the Race & Ethnicity Degree Requirement Review (2015-2016), and the creation of a Student Advisory Committee on R&E, currently underway.
Collaborating with the Center for Research Learning & Teaching to hire an Instructional Consultant with a focus on Race & Ethnicity courses.
Continuing the Laptop Loan Program to close the "digital divide" by providing laptops to more than 200 students per year, which is in the second of a four year pilot.
Initiating Transfer Student Initiatives and creating a variety of faculty, staff and student "task force" groups under the leadership of the LSA Transfer Student Manager and the LSA Dean's Office.
Extending the multiyear process of "Reinventing" the Comprehensive Studies Program to make it the best in the nation for supporting students of color, students from lower socioeconomic backgrounds, First Generation students, students from rural high schools and others with unequal access to resources.
Collaborating among LSA, REBUILD and CRTL on the "foundational courses" initiatives to improve the quality of inclusive undergraduate teaching in first and second year courses in STEM and beyond.
Renewing LSA's commitment to diversity, equity and inclusion in hiring, training, retaining and promoting staff members across LSA under the leadership of the LSA Staff Diversity Officer
Engaging staff by conducting a Diversity, Equity and Inclusion Administrative Forum Survey.
Leading ongoing efforts by the Undergraduate Education Climate Committee to work with faculty, staff and students to create a better, healthier campus climate.
Setting an expectation for LSA Graduate Admissions Chairs to attend Rackham's Admissions Workshop for Excellence and Diversity.
As we gather more feedback from the LSA community and learn from our experiences as we implement it, the plan will continue to evolve. We will update the formal plan regularly and post all changes on the LSA DEI website. We look forward to your continued participation in this process.


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Fitted vest in nude beige. Raw-edged paneling overlaid throughout in black. V-neck collar. Single-button closure at front. Adjustable belt at waist. Tonal stitching. Body: 68% polyamide, 32% cotton. Lining: 100% silk. Made in Italy.
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Separate names with a comma.
Discussion in 'Introductions' started by HTTP23, Jan 30, 2014.
Hi everyone
I hope I'll have a gret time here
Thanks !!
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Not a member yet? Join now
Hello, My husband and I are english speakers looking for an experienced Spoken Tamil Tutor--references required and any certifications or a language school that teaches Tamil. We want to learn Tamil as spoken in Chennai as opposed to proper Tamil. We'd love a recommendation. Thank you.


text:
by Stephanie
(La Mesa, CA)
On Wednesday, 1/18/2012 at 5:30pm my 19 year old brother was ridding his bike down a hill. He hit a bump in the sidewalk and his bike went out of control. He veered into the street and a car hit him, the impact threw my brother 20 feet away.
My brother is now in coma in critical condition. My family and I didn't find out he was in the hospital until 8:30pm that night. We tried to get a police report but received nothing until the next day. They gave us the case number, telling us that we had to go pick up the report, called a "traffic report".
I thought that when the accident happened they would have taken the bike as evidence of how the accident happened, but they didn't. My brother's friend took the bike home the next day. According to witnesses the driver got arrested because he was an illegal alien and got set back to Mexico. We don't know what to do.
Can we file a personal injury case against anyone to help pay my brother's medical bills?
Stephanie (La Mesa, CA):
Because the police effected an arrest your brother might have access to a Victims' Compensation Fund. Contact the San Diego County District Attorneys Office. They have a Victims' Access Department. They may have access to a Victims' Compensation Fund. That fund is available to help the victims of crime.
Call the following telephone numbers. Dong so should afford you access to the Victims of Crime Department...
Adult Probation Department
(619) 515-8202
Juvenile Records Department
(858) 694-4319
Once you contact the San Diego County Victims' Assistance Department you will be directed to one of the County's employees. That person will probably be a probation officer. Although the person who hit your son was arrested and deported without having to stand trial, there may be some difficulty in securing access to any available funds.
You have nothing to lose by contacting the department. If they can't help you they may be able to direct you to another department which will.
The above is general information. Laws change frequently, and across jurisdictions. You should get a personalized case evaluation from an attorney licensed in your state. Find a local attorney to give you a free case review here, or call (888) 647-2490.
Best of luck,
Judge Calisi
P.S. Please help us out by sharing this site...
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The man removing it from the lorry - who may have been tempted to discreetly chuck it in a nearby bin - is Piper's new boyfriend Amadu Sowe. The 27-year-old was Piper's publicist when she was a singer with Virgin Records. He gave up the music business to become a law student.
Piper, having travelled the galaxies as Dr Who's latest assistant, is clearly going up in the world. The house is in one of Hampstead's loveliest and leafiest streets.
Meanwhile Evans, the 38-year-old television host and media mogul, is trying to rebuild his career. He is thought to have spent £50 million in the four years he was married to Piper. Their homes are now so close that Piper visited her estranged husband's home on at least one occasion during yesterday's move to fetch water for thirsty removal men.
She came out of Evans's home carrying two or three glasses, allowing the workmen a thirst-quenching breather.
Their marriage was a stormy one. She was a teenage bride and he was drinking heavily. That it lasted four years - they split last year - was perhaps longer than most people predicted.
Now 23, Piper, a former teenage pop star, has rejuvenated her career in much the same way that Dr Who reinvents himself every few years.
Her role as the Time Lord's assistant Rose, opposite Christopher Eccleston, has been critically acclaimed. She has gone from being the young wife of an ageing mogul to a star in her own right.
Not that it is all comfy sofas, scatter cushions and coffee tables in Piper's new home. There was still a hint of rock 'n' roll glamour among the possessions. As well as the photograph of her soon-to-be-ex, the removal men grappled with two giant framed Sex Pistols' posters.
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- Marriage
- Pop
- Rock'n'roll
- Sex Pistols
- Teenagers
- Tv Show Hosts And Hostesses (tv People)


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Rev up your game with the Brunswick Powerkoil XF wrist positioner. The extended index finger support enhances side roll for improved length and back-end hook angle. Get yours today!
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My son and I went there for lunch. Wasn't too crowded and the food was delicious. They have a special lunch menu and at least 3 items were $7.49 and that included drink. The people were very nice.
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My son and I went there for lunch. Wasn't too crowded and the food was delicious. They have a special lunch menu and at least 3 items were $7.49 and that included drink. The people were very nice.
Waitress was great. Was welcomed as soon as came in door. Was very attentive. BBQ pork had a very good taste even without and of the four sauces available.
First of all the folks who work there are friendly and attentive the minute you walk in the door. The resturant is clean and welcoming.I ordered a side order of fried green tomatoes and a pulled pork sandwich. The food was hot and fresh, the tomatoes had a serious crunch on them. They were served with ranch dressing and very... 更多
Not bad at all for a local bbq restaurant. The menus were pleasing to the eyes. The waitress was quick to attend to us and food came out at a decent time. Good bbq sauce...the mild was actually mild, sweet n tangy was what it was, etc. It's good to find a bbq place that gave you sauce that was... 更多
Stopped in late afternoon / early evening on Saturday . I have visited several times before . Never any complaints on anything period with the business . The main item I have had most times is the smoked chicken which most folks rave about . Salads are very good . The location is always clean and offers a good sit... 更多
DH and I stopped for lunch here mostly because there were alot of cars in the parking lot. He had a rib plate - rated the ribs as a 7, slaw and green beans "good". I had the smoked pork salad which while good, was only iceberg lettuce. The pork on it was good. Generous portions. Service was only average,... 更多
Gotta say that I love the rack of ribs. The side of Mac and cheese with some potato salad topped off what I want to say is one of the best BBQ joints I ever been to. Price is low and the food and service is great. If your down this way don't miss out on this place.
Referred by a neighbor as we are new in town. We happened in on Friday night which was all the ribs you could eat. My husband enjoyed those and they were very tender. He picked the seasoned fires and slaw as his sides. Both were very good. My son got the buffalo bites pizza- 12 inch, certainly enough for 2... 更多
Passed by here many times on the way to the beach, but never at mealtime. Happened to be there for... 更多
I'm sorry to say this was quite a disappointing dining experience. To be BBQ restaurant there was a very limited... 更多
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Made from a phthalate-free PVC rubber, these finger sleeves allow you to probe and play in comfort. A great introductory toy to those new to anal, or for experienced anal pros the anal Fantasy Tushy Trainerz are a great addition to your collection as they can be placed on your favourite vibrating bullet or mini-vibe as well as fingers.
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UK DeliveryRoyal Mail Tracked 48– £2.95 usually delivered within 2 working days. Free over £20Royal Mail Tracked 24 - £3.95 on all orders, usually delivered within 1 working day Free over £50Royal Mail Special Delivery - £5.95 on all orders. Guaranteed next day delivery within the UK when ordered before 3.30pmSame Day DispatchOrder between 8am and 3.30pm, Monday to Friday and your order will be dispatched the same working day.
Please note when ordering Electro Sex items in conjunction with other products, items may be dispatched and delivered separately. This will not affect the delivery charge.
Collect in store
Pay for this item online and then choose this option to collect it for free from Harmony Store, 103 Oxford Street, London, W1D 2HF or Harmony 99a Charing Cross Road, London, WC2H 0DP. Click & Collect using Express Delivery is currently unavailable. Click & Collect orders will be received within 1-5 working days. You will be notified by telephone that your order has arrived. Please provide a working contact telephone number when checking out.
Deliveries to the Highlands and outside UK mainland may take longer.Click here for full information on deliveriesEUROPEAN DELIVERYRoyal Mail International - £12.95 or £9.95 delivered in 7-10 working daysClick here for full list of countries we deliver to and delivery information.
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Penske Diesel Technician in Jackson, Michigan
This opportunity will be Tuesday - Friday 1:30pm - 10:00pm AND
Saturday 7:00am - 3:30pm
Perform minor component repair and all aspects of preventative maintenance on the newest and best maintained fleet of power, refrigerated and non-powered truck and trailer equipment in the industry.
We have industry leading vehicle maintenance and repair technology, tools and experts in the maintenance field and industry. You will receive state of the art training each year on a variety of OEM equipment. Many of our technicians have been trained and certified through Penske's Technician Certification Program which is ASE (Automotive Service Excellence) certified as a CASE (Continuing Automotive Service Education) provider.
Major Responsibilities:
Demonstrate proficiency in the repair and diagnosis of - with some assistance: Engines (gas and diesel), Power train to include differentials, transmissions, clutches, drive shafts, PTO's and wheel ends, Electrical systems including starters and alternators, HVAC systems, Steering systems, Electronics to include ECM's, ECU's, sensors etc., Engine bolt on items such as turbos, fan clutches, injectors, cooling system etc., Brake systems including ABS, Suspension systems (spring and air)
Perform mechanical and general appearance reconditioning of equipment for "trade-ins" and prepare new equipment for delivery.
Identify and determine parts required for repair of disassembled units
Perform all levels of preventive maintenance services on truck and trailer equipment
Identify warrantable repairs and document on repair order
Maintain work area appearance and safety
Road test Vehicles when necessary to diagnose malfunctions or to ensure that they are working properly.
Use hand tools such as screwdrivers, pliers, wrenches, pressure gauges, and precision instruments, as well as power tools such as pneumatic wrenches, welding equipment, and jacks and hoists.
Inspect brake systems, steering mechanisms, wheel bearings, and other important parts to ensure that they are in proper operating condition.
Perform routine maintenance such as changing oil, checking batteries, and lubricating equipment and machinery.
Adjust and replace brakes, tighten bolts and screws, and reassemble equipment.
Raise trucks, buses, and heavy parts or equipment using hydraulic jacks or hoists.
Inspect, test, and listen to defective equipment to diagnose malfunctions, using test instruments such as handheld computers, motor analyzers, chassis charts, and pressure gauges.
Examine and adjust protective guards, loose bolts, and specified safety devices.
Inspect and verify dimensions and clearances of parts to ensure conformance to factory specifications.
Specialize in repairing and troubleshooting of major components such as engine, transmissions and differentials, to include replacing complete assemblies, turbochargers, fuel system components etc.
Other projects and tasks as assigned by supervisor
2-4 years practical experience with tractor trailer maintenance preferred
High school diploma or equivalent required
Vocational/Technical or certification preferred
Specialized training in the repair and replacement of vehicle components preferred
Proficiency in the use of shop tools required
A valid drivers license is required
Current CDL license with air brake certification preferred, willingness to acquire CDL if you do not have one.
Basic computer skills preferred for data entry into maintenance systems.
Ability to work in non-climate controlled conditions required
Willingness to travel as necessary within the district (customers yards, close geographical area and training sites), work the required schedule, work at the specific location required, complete Penske employment application, submit to a background investigation (to include past employment, education, and criminal history) and drug screening are required.
Physical Requirements:
-The physical and mental demands described here are representative of those that must be met by an associate to successfully perform the essential functions of this job. Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions.
-The associate will be required to remember and understand certain instructions, guidelines or other information. The associate must be able to see and verbally
communicate. Specific vision abilities required by this job include close vision, distance vision, peripheral vision, depth perception and the ability to adjust focus.
-While performing the duties of this job, the associate will be required to move frequently, stand, walk, and sit. The associate is frequently required to use hands to touch, handle, and feel, and to reach with hands and arms. The associate must be able to regularly lift and/or move up to 50lbs/23kg and occasionally lift and/or move up to 100lbs/45kg.
Penske is an Equal Opportunity Employer, including individuals with disabilities and protected veterans.
Penske Truck Leasing Co., L.P., headquartered in Reading, Pennsylvania, is a partnership of Penske Corporation, Penske Automotive Group, General Electric Capital Corporation and Mitsui & Co., Ltd. A leading global transportation services provider, Penske operates more than 216,000 vehicles and serves customers from more than 1,000 locations in North America, South America, Europe, Australia, and Asia. Product lines include full-service truck leasing, contract maintenance, commercial and consumer truck rentals, used truck sales, transportation and warehousing management and supply chain management solutions. Visit http://www.GoPenske.com to learn more.
Work Locations: 2012 Dunigan Drive Jackson, MI
Primary Location: United States-Michigan-Jackson
Job: Vehicle Maintenance/Mechanics/Technicians
Penske (Oracle) Job Name: Vehicle Maintenance/Mechanics/Technicians
Req ID: 1701019


text:
Spectacular opportunity! First time being offered. Equestrian's dream to own a magnificent 48 acre horse farm in the heart of Colts Neck. This property features the original farmhouse with wide plank hardwood floors, thirty eight stalls, indoor riding rink and large utility barn for machinery. Apartment above barn. There are eight gorgeous paddocks with watering system. Tranquil and beautiful this property is a must see!
Listing Courtesy of Shore Homes Shirvanian Realty


text:
LAFAYETTE, Ind. (WLFI) — Police have released a surveillance photograph from Friday's attempted robbery at a Lafayette KFC.
Police responded to the Kentucky Fried Chicken on Teal Road on Friday, Nov. 18, around 9 p.m. to a report of a man in the restaurant with a handgun.
Police said the incident is being investigated as an attempted robbery.
An extensive search of the area was conducted, but no subjects were located.
Anyone with information is asked to contact the Lafayette Police Department at 765-807-1200 or the anonymous WeTip Hotline at 800-78-CRIME.


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Struggling with business case for part time working(10 Posts)
KristinaFranziska Wed 26-Jun-13 11:34:54
mymatemax Sun 23-Jun-13 22:01:45
Poosnu Sun 23-Jun-13 21:52:20
princessx Tue 14-May-13 16:58:58
lovefreelance Tue 14-May-13 16:49:20
princessx Tue 14-May-13 15:42:03
chanie44 Tue 14-May-13 14:49:21
chanie44 Tue 14-May-13 14:40:09
Stubbed56 Tue 14-May-13 10:56:38
princessx Tue 14-May-13 10:52:00
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Bubble Guppies and Friends
By: SpankMeApps
Welcome to the walkthrough for the iOS game Bubble Guppies and Friends, if you are looking for ways to make it to the next level, and to improve gaming experience as a master player, you've come to the right place. Here you will find Bubble Guppies and Friends tips, tricks and guides, as well as the opportunity to share your own discoveries to help others move on and beat the game.
If you can't find the answer to your question you are welcome to post it in the comments section below. This way others who know the answer can help you by sharing their own tips and advices.
Bubble Guppies and Friends game app is developed by SpankMeApps and available on iTunes and Google Play. For more details on the app, check out our review.
- App name: Bubble Guppies and Friends
- Seller: SpankMeApps
- Category: Family
- Updated: Sep 17, 2013
Bubble Guppies and Friends iOS/Android Gameplay
Check out these tutorial for all levels of Bubble Guppies and Friends. We'll continue to update this list with the latest answers as new levels are released.
Bubble Guppies and Friends Answers
- Basic Game Guide Part One - dora the explorer and friends paw patrol bubble guppies wallykazam full kids game
Hit like if this helped you!
Until the Walkthrough is completed, feel free to ask for help in the comments section.


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This adorable baby girl needs a bath, but her mommy is very busy today. Can you clean her up? Fill the tub with warm water and make some soap bubbles to keep the baby smiling! You can also place some flowers and toys in the bathtub, so she won't get bored. Wash her with some gentle soap and shampoo. Now that she's all clean, you can take care of her! Use baby powder on her skin, so it won't get irritated. In the next level of the game, you can choose a cute hairstyle for the adorable little girl and dress her up. Impress her with your fashion choices!
Author: girlsplay Tags: baby, bath, care, dress up, fashion, hair,


text:
Growth hormon therapy
Is it safe of growth hormone therapy? Have any side effect? What are the result of therapy.? Is it effective? On which age it shows best result?
25 Views
Doctor Answers (1) on Growth hormon therapy
Dr. Chethan R S
Bangalore | General Physician
INR 250 for 24 hrsCHAT NOW
If an exogenous source was provided, the growth region of the bone known as the epiphyseal plate has already shut down, so you'd only grow laterally. If you get doses of growth hormone as an adult, you develop a condition known as acromegaly...
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Transparent Lcd - Chinaprice: contact company for price
objects through the monitor's viewing surface. The ChariotSmart has been
researching the use of liquid crystal optical film as a substitute for
traditional LCD backlights with the goal of commercializing a display
which allows a user's gaze to pass through to the opposite side when the
screen is powered on. We are hoping to market the screens to the
amusement industry, where they will be used for activities such as
watching your family while watching a movie, watching a movie while
another movie plays in the distance, and of course playing a video game
while watching a movie
Transparent Lcd
Feel free to contact us with all your questions
Company Contact:
- Posted By: chariotsmart
- Phone: 8615824254689
- Address: No.298 Technology Center, Xueshi road, china, China
- Email:
- Website: http://www.chariotsmart.com
Published date: September 7, 2012 -
- Business Description: ChariotSmart, a high tech company with own independent R & D institutions and service team, offers an innovative platform for interactive media displays. We give advertisers and media companies, event and tradeshow organizers the ability to display digital content in various public locations, including convention centers, retail spaces, airports, exhibition spaces and other commercial locations.
ChariotSmart s lines of products have been installed in worldwide locations by major international brands. ChariotSmart has delivered applications for home entertainment, advertising, digital signage, education, corporate promotions, and etc. ChariotSmart displays are opening a new world of possibilities for brands to communicate with target consumers.
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Bicheng provides RD, high-tech, IT research companies and organizations, large and small with PCB prototypes. It covers: 1) 1-32 Layers, 0.3-6mm thick, Heavy copper (2-10 oz) 2) High Tg 170, High CTI 600V 3) Impedance control +/-10% 4) 1+C+1 HDI, Bur...
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6a05 6a10Electronics - Manufacturing - kingtronics international company - China - September 7, 2012 - contact company for price
Axial leads diode R-6 Package diode High surge current capability Low leakage and forward voltage drop Available with 6A05, 6A1, 6A2, 6A4, 6A6, 6A8, 6A10 6a05 6a10 Please inquiry for your need now
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text:
Ericdress Casual Plain One Shoulder Hollow T-Shirt
Ericdress BFstyle Patchwork Zipper Jacket
Here ericdress.com shows customers a fashion collection of current wedding dress for prom.You can find many great items. They all have high quality and reasonable price. You can get big discount sometimes, because we always do promotions. If you need wedding dress for prom,come here to choose. We give you good items and services.
Ericdress Shining Snowflake Earring for Women(for one)
Ericdress Letter Craving Ring For Lovers
Ericdress Shiny Rhinestone Flower Ring For Women
Ericdress Classic Diamond Ring For Women
Ericdress Heart Design Diamond Ring For Lovers
Ericdress Sparking Zircon Ring for Women
Ericdress Water Drop Crown Ring for Women
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Delicate Flower Diamante Ring for Women
Metal Leaf Shaped Unique Bracelet for Arm
Ericdress Punk Style Bullet Bracelet For Men
Ericdress Shining Butterfly Ring for Women
Ericdress Hollow Star Silicone Bracelet For Men
Golden Faery Sweater Chain for Women
Ericdress Simple Chain Tassels Necklace for Women
Ericdress Heart-Shaped Imitation Diamond Ring for Wedding
Ericdress Flirtatious Hollow Peacock Gem Earrings(Price For A Pair)
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Ericdress Wooden Leaf Pendant Long Necklace for Mori Girl
Bateau Neck Appliques Backless Prom Dress
Ericdress Jewel Neck Beading Sequins Prom Dress


text:
Filter by:
Content type:
Stage 1&2
Stage 2&3
Stage 3&4
Stage 4&5
Challenge level:
Annie and Ben are playing a game with a calculator. What was
Annie's secret number?
The value of the circle changes in each of the following problems. Can you discover its value in each problem?
This magic square has operations written in it, to make it into a
maze. Start wherever you like, go through every cell and go out a
total of 15!
Zumf makes spectacles for the residents of the planet Zargon, who
have either 3 eyes or 4 eyes. How many lenses will Zumf need to
make all the different orders for 9 families?
There are three buckets each of which holds a maximum of 5 litres.
Use the clues to work out how much liquid there is in each bucket.
On a calculator, make 15 by using only the 2 key and any of the
four operations keys. How many ways can you find to do it?
Find another number that is one short of a square number and when
you double it and add 1, the result is also a square number.
There are 44 people coming to a dinner party. There are 15 square
tables that seat 4 people. Find a way to seat the 44 people using
all 15 tables, with no empty places.
Use the information to work out how many gifts there are in each
Can you work out how many flowers there will be on the Amazing Splitting Plant after it has been growing for six weeks?
Using the statements, can you work out how many of each type of
rabbit there are in these pens?
At the beginning of May Tom put his tomato plant outside. On the same day he sowed a bean in another pot. When will the two be the same height?
Throw the dice and decide whether to double or halve the number. Will you be the first to reach the target?
Twizzle, a female giraffe, needs transporting to another zoo. Which
route will give the fastest journey?
Look on the back of any modern book and you will find an ISBN code. Take this code and calculate this sum in the way shown. Can you see what the answers always have in common?
There were 22 legs creeping across the web. How many flies? How many spiders?
Can you arrange 5 different digits (from 0 - 9) in the cross in the
way described?
Claire thinks she has the most sports cards in her album. "I have
12 pages with 2 cards on each page", says Claire. Ross counts his
cards. "No! I have 3 cards on each of my pages and there are. . . .
Peter, Melanie, Amil and Jack received a total of 38 chocolate
eggs. Use the information to work out how many eggs each person
This problem is based on the story of the Pied Piper of Hamelin. Investigate the different numbers of people and rats there could have been if you know how many legs there are altogether!
Cherri, Saxon, Mel and Paul are friends. They are all different
ages. Can you find out the age of each friend using the
The clockmaker's wife cut up his birthday cake to look like a clock
face. Can you work out who received each piece?
We can arrange dots in a similar way to the 5 on a dice and they
usually sit quite well into a rectangular shape. How many
altogether in this 3 by 5? What happens for other sizes?
A game for 2 people. Use your skills of addition, subtraction, multiplication and division to blast the asteroids.
Use your logical-thinking skills to deduce how much Dan's crisps and ice-cream cost altogether.
Go through the maze, collecting and losing your money as you go.
Which route gives you the highest return? And the lowest?
If the numbers 5, 7 and 4 go into this function machine, what
numbers will come out?
These eleven shapes each stand for a different number. Can you use the multiplication sums to work out what they are?
These sixteen children are standing in four lines of four, one behind the other. They are each holding a card with a number on it. Can you work out the missing numbers?
Here are the prices for 1st and 2nd class mail within the UK. You have an unlimited number of each of these stamps. Which stamps would you need to post a parcel weighing 825g?
The Scot, John Napier, invented these strips about 400 years ago to
help calculate multiplication and division. Can you work out how to
use Napier's bones to find the answer to these multiplications?
Suppose we allow ourselves to use three numbers less than 10 and
multiply them together. How many different products can you find?
How do you know you've got them all?
What is happening at each box in these machines?
In a Magic Square all the rows, columns and diagonals add to the 'Magic Constant'. How would you change the magic constant of this square?
Put a number at the top of the machine and collect a number at the
bottom. What do you get? Which numbers get back to themselves?
Well now, what would happen if we lost all the nines in our number
system? Have a go at writing the numbers out in this way and have a
look at the multiplications table.
Use your logical reasoning to work out how many cows and how many
sheep there are in each field.
Put operations signs between the numbers 3 4 5 6 to make the highest possible number and lowest possible number.
EWWNP means Exploring Wild and Wonderful Number Patterns Created by Yourself! Investigate what happens if we create number patterns using some simple rules.
This number has 903 digits. What is the sum of all 903 digits?
Skippy and Anna are locked in a room in a large castle. The key to that room, and all the other rooms, is a number. The numbers are locked away in a problem. Can you help them to get out?
Tom and Ben visited Numberland. Use the maps to work out the number of points each of their routes scores.
Can you find which shapes you need to put into the grid to make the
totals at the end of each row and the bottom of each column?
Explore Alex's number plumber. What questions would you like to ask? What do you think is happening to the numbers?
This activity focuses on doubling multiples of five.
This task combines spatial awareness with addition and multiplication.
This challenge combines addition, multiplication, perseverance and even proof.
What happens when you add the digits of a number then multiply the result by 2 and you keep doing this? You could try for different numbers and different rules.
This group activity will encourage you to share calculation strategies and to think about which strategy might be the most efficient.
Can you design a new shape for the twenty-eight squares and arrange
the numbers in a logical way? What patterns do you notice?


text: 1967 births Category page 3,091pages on this wiki Add New Page Edit History Talk0 Sorting type: Most visited Most visited Alphabetical | Pages in category "1967 births" Russell Swan Dan Foley Denise Martin Deena Bennett Jill Behm Stacey Powell Tyrone Davis Retrieved from "http://survivor.wikia.com/wiki/Category:1967_births?oldid=326668" Ad blocker interference detected! Wikia is a free-to-use site that makes money from advertising. We have a modified experience for viewers using ad blockers Wikia is not accessible if you've made further modifications. Remove the custom ad blocker rule(s) and the page will load as expected. Categories: Contestants by year of birth


text:
Simplest scenario:
if ($_POST) {
// Execute code (such as database updates) here.
// Redirect to this page.
header("Location: " . $_SERVER['REQUEST_URI']);
Use REQUEST_URI. Do not use PHP_SELF as in most CMS systems and frameworks PHP_SELF would refer to /index.php.
A snippet of code:
if (count($_POST)) {
// process the POST data
// your code here- so for example to log a user in, register a new account..
// ...make a payment...etc
// redirect to the same page without the POST data, including any GET info you
// want, you could add a clause to detect whether processing the post data has
// been successful or not, depending on your needs
$get_info = "?status=success";
// if not using rewrite
// header("Location: ".$_SERVER['PHP_SELF'].$get_info);
// if using apache rewrite
header("Location: ".$_SERVER['REQUEST_URI'].$get_info);
HTML form
PHP app
reads $_POST
sends 303 header
receives header
redirected to
new page
PHP app
reads $_GET
does whatever
A common use is in login authentication. That's the process flow when user submits the login form. PHP app authenticates user via $_POST vars. Sends a 303 header back to browser when the user has successfully authenticated. So user is redirected to a new page.
Callee.php (Is called twice.)
if ($_POST) {
header("Location: ". $_SERVER['REQUEST_URI']. 'Query2');
// PART1: Use $_POST and $_GET to execute database updates here...
// Now any display (i.e. echo or print) will come after the header.
// ...
die; // When done, GET 'myself' to execute PART2 below.
// PART2: Results page goes here...
echo 'PART 2 display output: '; var_dump($_GET);
Notice there are two query strings involved
Look what var_dump says about $_GET:
PART 2 display output: array(1) { ["Query1Query2"]=> string(0) "" }
Issues with putting header at the end of the POST section like this:
header("Location: ". $_SERVER['REQUEST_URI']. 'Query2'); die;
The php manual says: "Remember that header() must be called before any actual output is sent, either by normal HTML tags, blank lines in a file, or from PHP. It is a very common error to read code with include, or require, functions, or another file access function, and have spaces or empty lines that are output before header() is called. The same problem exists when using a single PHP/HTML file."
However if you need to build 'Query2' based on what happens in the POST section, it may need to be at the bottom of the POST section. This is ok, so long as you don't try to insert any echo's above it, not even for testing.


text:
theres a little light labelled L next to the power, rx and tx leds that flashes a couple of times, giving me the impression the data is being recieved! does anybody know if my assumption is correct
and have any ideas
public void start() { try{ portid1.getPortIdentifier("COM4"); // portid1.open("start", 2000); serialPort1 = (SerialPort) portid1.open("connect", 2000); JOptionPane.showMessageDialog(null,"Connection Established"); } catch (Exception e) { JOptionPane.showMessageDialog(null,e); // System.out.println(e); }
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text:
Urban Beauty Salon and Spa
Beauty Salon
Urban Beauty Salon and Spa is one of the most sought after salons for hair design, extensions, care and maintenance, blonding and highlights.
Our salon is also one of the best in San Diego for all your skin care needs: We provide waxing, full service facials, peels and custom airbrush tanning.
Client care and supreme satisfaction is what we strive for with each of our clients.
Print this page
PCA SKIN® Clinical Care Products and PCA® MEN products are scientifically formulated using technically advanced, all–natural ingredients to nourish, hydrate
L'Oréal Professionnel in-salon treatments are professionally formulated to repair, enhance, strengthen, nourish and protect depending on the needs of your
Framesi hair products are known for their quality and high performance, always respecting the integral structure of the hair. Each
UNITE Eurotherapy, a boutique, salon–selective brand, combines European Creativity and American ingenuity in one comprehensive professional hair care line that
Eufora's advanced technology utilizes important botanical extracts that have been scientifically proven to benefit the hair, scalp and skin. Designed
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