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If Ralph Lauren were as rich in irony as he is in romance, he would commission a contemporary artist to copy the large Victorian mural that served as a backdrop yesterday for his splendid fall collection, held amid the dark paneling and Persian carpets of his headquarters on Madison Avenue. Except that Mr. Lauren should substitute his own likeness for the faces of the high-hatted English gentlemen milling around in the scene, so Waldo-like is his immersion into that supercivilized world.
In his program notes, Mr. Lauren made no mention of the painting, or the English toff style that had influenced the clothes, and in a way he was correct. For it was only the elegant form of that era that seemed to interest him -- the classic rightness of a cutaway slicing over a pair of morning-striped trousers. But those pants were cut for female curves, low and tight, and would strain an old boy's sense of taste and respectability beyond belief.
That's what Mr. Lauren did so well in this collection: he kept the sex lid on. Here were all these fine-looking Edwardians, turned out in proper topcoats and jodhpurs and other examples of masculine swank. Yet all the while there was this erotic tension between the strict tailoring and Mr. Lauren's almost louche treatment of beaded black lace tops.
Apart from white cotton shirts and a lick of gold embroidery entwining seductively down the bare back of an evening dress, the collection was all black. A year ago, in another collection that revisited the 19th century, Nicolas Ghesquiere located the modern elements in old forms, and brought them forward, using black as the only logical hue to convey elegance in a world that doesn't exactly prize it anymore. Mr. Lauren was on the same wavelength, but on his terms.
And though humor has never been his forte -- if he had some, he would have played off that huge slick mural and given one of his models the joke of a top hat -- he at least seems more reactive to the times. One of the dresses that closed the show scooped low under the arms, around the back and ended in a splash of piano fringe.
Helmut Lang's show, opening yesterday with a jolt of that tense, electronic music he likes, stayed on a familiar track of sharp tailoring and esoteric layering that all-too-quickly sputtered out. Underneath his car coats were T-shirts or sweaters worn in layers, some with gold lamé insets or inexplicable flaps of gold trailing from the hem of the coats.
He has done this sort of thing before, but it was hard to make out a new direction, and for the most part the clothes looked heavy or overthought, even gimmicky. A gold pleated skirt came out wound at the hips with what looked like clear plastic packaging strips. A fine bunch of chunky sweaters, molded like soft body armor, got the blood racing, but it wasn't enough.Continue reading the main story


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Emerging Infectious Diseases journal
Expedited Ahead-of-Print Articles
Persistence of Zika Virus in Breast Milk after Infection in Late Stage of Pregnancy J. R. Sotelo et al. May 2017
Volume 23, Number 3—March 2017 PDF Version [PDF - 8.69 MB - 200 pages]
Epidemiology of Invasive Haemophilus influenzae Disease, Europe, 2007–2014
R. Whittaker et al.View Abstract
We describe the epidemiology of invasive Haemophilus influenzae disease during 2007–2014 in 12 European countries and assess overall H. influenzae disease trends by serotype and patient age. Mean annual notification rate was 0.6 cases/100,000 population, with an increasing annual trend of 3.3% (95% CI 2.3% to 4.3%). The notification rate was highest for patients <1 month of age (23.4 cases/100,000 population). Nontypeable H. influenzae (NTHi) caused 78% of all cases and showed increasing trends among persons <1 month and >20 years of age. Serotype f cases showed an increasing trend among persons >60 years of age. Serotype b cases showed decreasing trends among persons 1–5 months, 1–4 years, and >40 years of age. Sustained success of routine H. influenzae serotype b vaccination is evident. Surveillance systems must adopt a broad focus for invasive H. influenzae disease. Increasing reports of NTHi, particularly among neonates, highlight the potential benefit of a vaccine against NTHi.
Medscape CME Activity
Three Cases of Neurologic Syndrome Caused by Donor-Derived Microsporidiosis PDF Version [PDF - 2.02 MB - 9 pages]R. M. Smith et al.View SummaryView Abstract
Encephalitozoon cuniculi was transmitted from an infected donor to 3 solid organ recipients, 1 of whom died.Cite This Article
In April 2014, a kidney transplant recipient in the United States experienced headache, diplopia, and confusion, followed by neurologic decline and death. An investigation to evaluate the possibility of donor-derived infection determined that 3 patients had received 4 organs (kidney, liver, heart/kidney) from the same donor. The liver recipient experienced tremor and gait instability; the heart/kidney and contralateral kidney recipients were hospitalized with encephalitis. None experienced gastrointestinal symptoms. Encephalitozoon cuniculi was detected by tissue PCR in the central nervous system of the deceased kidney recipient and in renal allograft tissue from both kidney recipients. Urine PCR was positive for E. cuniculi in the 2 surviving recipients. Donor serum was positive for E. cuniculi antibodies. E. cuniculi was transmitted to 3 recipients from 1 donor. This rare presentation of disseminated disease resulted in diagnostic delays. Clinicians should consider donor-derived microsporidial infection in organ recipients with unexplained encephalitis, even when gastrointestinal manifestations are absent.
EID Smith RM, Muehlenbachs A, Schaenmann J, Baxi S, Koo S, Blau D, et al. Three Cases of Neurologic Syndrome Caused by Donor-Derived Microsporidiosis. Emerg Infect Dis. 2017;23(3):387-395. https://dx.doi.org/10.3201/eid2303.161580 AMA Smith RM, Muehlenbachs A, Schaenmann J, et al. Three Cases of Neurologic Syndrome Caused by Donor-Derived Microsporidiosis. Emerging Infectious Diseases. 2017;23(3):387-395. doi:10.3201/eid2303.161580. APA Smith, R. M., Muehlenbachs, A., Schaenmann, J., Baxi, S., Koo, S., Blau, D....Zaki, S. (2017). Three Cases of Neurologic Syndrome Caused by Donor-Derived Microsporidiosis. Emerging Infectious Diseases, 23(3), 387-395. https://dx.doi.org/10.3201/eid2303.161580.
Medscape CME Activity
Epidemiology of Mycobacterium bovis Disease in Humans in England, Wales, and Northern Ireland, 2002–2014 PDF Version [PDF - 3.41 MB - 10 pages]J. A. Davidson et al.View SummaryView Abstract
Despite slightly increased cases in these areas, human infection with this cattle pathogen remains rare.Cite This Article
Despite control efforts, Mycobacterium bovis incidence among cattle remains high in parts of England, Wales, and Northern Ireland, attracting political and public health interest in potential spread from animals to humans. To determine incidence among humans and to identify associated factors, we conducted a retrospective cohort analysis of human M. bovis cases in England, Wales, and Northern Ireland during 2002–2014. We identified 357 cases and observed increased annual case numbers (from 17 to 35) and rates. Most patients were >65 years of age and born in the United Kingdom. The median age of UK-born patients decreased over time. For 74% of patients, exposure to risk factors accounting for M. bovis acquisition, most frequently consumption of unpasteurized milk, was known. Despite the small increase in case numbers and reduction in patient age, M. bovis infection of humans in England, Wales, and Northern Ireland remains rare.
EID Davidson JA, Loutet MG, O'Connor C, Kearns C, Smith R, Lalor MK, et al. Epidemiology of Mycobacterium bovis Disease in Humans in England, Wales, and Northern Ireland, 2002–2014. Emerg Infect Dis. 2017;23(3):377-386. https://dx.doi.org/10.3201/eid2303.161408 AMA Davidson JA, Loutet MG, O'Connor C, et al. Epidemiology of Mycobacterium bovis Disease in Humans in England, Wales, and Northern Ireland, 2002–2014. Emerging Infectious Diseases. 2017;23(3):377-386. doi:10.3201/eid2303.161408. APA Davidson, J. A., Loutet, M. G., O'Connor, C., Kearns, C., Smith, R., Lalor, M. K....Zenner, D. (2017). Epidemiology of Mycobacterium bovis Disease in Humans in England, Wales, and Northern Ireland, 2002–2014. Emerging Infectious Diseases, 23(3), 377-386. https://dx.doi.org/10.3201/eid2303.161408.
Whole-Genome Analysis of Bartonella ancashensis, a Novel Pathogen Causing Verruga Peruana, Rural Ancash Region, Peru
K. E. Mullins et al.View Abstract
The genus Bartonella contains >40 species, and an increasing number of these Bartonella species are being implicated in human disease. One such pathogen is Bartonella ancashensis, which was isolated in blood samples from 2 patients living in Caraz, Peru, during a clinical trial of treatment for bartonellosis. Three B. ancashensis strains were analyzed by using whole-genome restriction mapping and high-throughput pyrosequencing. Genome-wide comparative analysis of Bartonella species showed that B. ancashensis has features seen in modern and ancient lineages of Bartonella species and is more related to B. bacilliformis. The divergence between B. ancashensis and B. bacilliformis is much greater than what is seen between known Bartonella genetic lineages. In addition, B. ancashensis contains type IV secretion system proteins, which are not present in B. bacilliformis. Whole-genome analysis indicates that B. ancashensis might represent a distinct Bartonella lineage phylogenetically related to B. bacilliformis.
Zika Virus RNA Replication and Persistence in Brain and Placental Tissue
J. Bhatnagar et al.View Abstract
Zika virus is causally linked with congenital microcephaly and may be associated with pregnancy loss. However, the mechanisms of Zika virus intrauterine transmission and replication and its tropism and persistence in tissues are poorly understood. We tested tissues from 52 case-patients: 8 infants with microcephaly who died and 44 women suspected of being infected with Zika virus during pregnancy. By reverse transcription PCR, tissues from 32 (62%) case-patients (brains from 8 infants with microcephaly and placental/fetal tissues from 24 women) were positive for Zika virus. In situ hybridization localized replicative Zika virus RNA in brains of 7 infants and in placentas of 9 women who had pregnancy losses during the first or second trimester. These findings demonstrate that Zika virus replicates and persists in fetal brains and placentas, providing direct evidence of its association with microcephaly. Tissue-based reverse transcription PCR extends the time frame of Zika virus detection in congenital and pregnancy-associated infections.
Comparison of Sputum-Culture Conversion for Mycobacterium bovis and M. tuberculosis
C. Scott et al.View Abstract
Current US guidelines recommend longer treatment for tuberculosis (TB) caused by pyrazinamide-resistant organisms (e.g., Mycobacterium bovis) than for M. tuberculosis TB. We compared treatment response times for patients with M. bovis TB and M. tuberculosis TB reported in the United States during 2006–2013. We included culture-positive, pulmonary TB patients with genotyping results who received standard 4-drug treatment at the time of diagnosis. Time to sputum-culture conversion was defined as time between treatment start date and date of first consistently culture-negative sputum. We analyzed 297 case-patients with M. bovis TB and 30,848 case-patients with M. tuberculosis TB. After 2 months of treatment, 71% of M. bovis and 65% of M. tuberculosis TB patients showed conversion of sputum cultures to negative. Likelihood of culture conversion was higher for M. bovis than for M. tuberculosis, even after controlling for treatment administration type, sex, and a composite indicator of bacillary burden.
Spatiotemporal Fluctuations and Triggers of Ebola Virus Spillover
J. Schmidt et al.View Abstract
Because the natural reservoir of Ebola virus remains unclear and disease outbreaks in humans have occurred only sporadically over a large region, forecasting when and where Ebola spillovers are most likely to occur constitutes a continuing and urgent public health challenge. We developed a statistical modeling approach that associates 37 human or great ape Ebola spillovers since 1982 with spatiotemporally dynamic covariates including vegetative cover, human population size, and absolute and relative rainfall over 3 decades across sub-Saharan Africa. Our model (area under the curve 0.80 on test data) shows that spillover intensity is highest during transitions between wet and dry seasons; overall, high seasonal intensity occurs over much of tropical Africa; and spillover intensity is greatest at high (>1,000/km2) and very low (<100/km2) human population densities compared with intermediate levels. These results suggest strong seasonality in Ebola spillover from wild reservoirs and indicate particular times and regions for targeted surveillance.
Mycobacterium tuberculosis Transmission among Elderly Persons, Yamagata Prefecture, Japan, 2009–2015
J. Seto et al.View Abstract
In many countries with low to moderate tuberculosis (TB) incidence, cases have shifted to elderly persons. It is unclear, however, whether these cases are associated with recent Mycobacterium tuberculosis transmission or represent reactivation of past disease. During 2009–2015, we performed a population-based TB investigation in Yamagata Prefecture, Japan, using in-depth contact tracing and 24-loci variable-number tandem-repeat typing optimized for Beijing family M. tuberculosis strains. We analyzed 494 strains, of which 387 (78.3%) were derived from elderly patients. Recent transmission with an epidemiologic link was confirmed in 22 clusters (70 cases). In 17 (77.3%) clusters, the source patient was elderly; 11 (64.7%) of the 17 clusters occurred in a hospital or nursing home. In this setting, the increase in TB cases was associated with M. tuberculosis transmissions from elderly persons. Prevention of transmission in places where elderly persons gather will be an effective strategy for decreasing TB incidence among predominantly elderly populations.
Use of Mass-Participation Outdoor Events to Assess Human Exposure to Tickborne Pathogens
J. L. Hall et al.View Abstract
Mapping the public health threat of tickborne pathogens requires quantification of not only the density of infected host-seeking ticks but also the rate of human exposure to these ticks. To efficiently sample a high number of persons in a short time, we used a mass-participation outdoor event. In June 2014, we sampled ≈500 persons competing in a 2-day mountain marathon run across predominantly tick-infested habitat in Scotland. From the number of tick bites recorded and prevalence of tick infection with Borrelia burgdoferi sensu lato and B. miyamotoi, we quantified the frequency of competitor exposure to the pathogens. Mass-participation outdoor events have the potential to serve as excellent windows for epidemiologic study of tickborne pathogens; their concerted use should improve spatial and temporal mapping of human exposure to infected ticks.
Epidemiology of Nontuberculous Mycobacterial Lung Disease and Tuberculosis, Hawaii, USA
J. Adjemian et al.View Abstract
Previous studies found Hawaiians and Asian-Americans/Pacific Islanders to be independently at increased risk for nontuberculous mycobacterial pulmonary disease (NTMPD) and tuberculosis (TB). To better understand NTM infection and TB risk patterns in Hawaii, USA, we evaluated data on a cohort of patients in Hawaii for 2005–2013. Period prevalence of NTMPD was highest among Japanese, Chinese, and Vietnamese patients (>300/100,000 persons) and lowest among Native Hawaiians and Other Pacific Islanders (50/100,000). Japanese patients were twice as likely as all other racial/ethnic groups to have Mycobacterium abscessus isolated (adjusted odds ratio 2.0, 95% CI 1.2–3.2) but were not at increased risk for infection with other mycobacteria species. In contrast, incidence of TB was stable and was lowest among Japanese patients (no cases) and highest among Filipino, Korean, and Vietnamese patients (>50/100,000). Substantial differences exist in the epidemiology of NTMPD by race/ethnicity, suggesting behavioral and biologic factors that affect disease susceptibility.
New Mycobacterium tuberculosis Complex Sublineage, Brazzaville, Congo
S. Malm et al.View Abstract
Tuberculosis is a leading cause of illness and death in Congo. No data are available about the population structure and transmission dynamics of the Mycobacterium tuberculosis complex strains prevalent in this central Africa country. On the basis of single-nucleotide polymorphisms detected by whole-genome sequencing, we phylogenetically characterized 74 MTBC isolates from Brazzaville, the capital of Congo. The diversity of the study population was high; most strains belonged to the Euro-American lineage, which split into Latin American Mediterranean, Uganda I, Uganda II, Haarlem, X type, and a new dominant sublineage named Congo type (n = 26). Thirty strains were grouped in 5 clusters (each within 12 single-nucleotide polymorphisms), from which 23 belonged to the Congo type. High cluster rates and low genomic diversity indicate recent emergence and transmission of the Congo type, a new Euro-American sublineage of MTBC.
Pulmonary Nontuberculous Mycobacteria–Associated Deaths, Ontario, Canada, 2001–2013
T. K. Marras et al.View Abstract
Survival implications of nontuberculous mycobacterial pulmonary disease (NTM-PD) and NTM pulmonary isolation without disease (NTM-PI) are unclear. To study deaths associated with NTM-PD and NTM-PI and differences in survival between them, we conducted a population-based cohort study of persons with microbiologically defined NTM-PD or NTM-PI diagnosed during 2001–2013 in Ontario, Canada. We used propensity score matching and Cox proportional hazards models to compare survival. Among 9,681 NTM-PD patients and 10,936 NTM-PI patients, 87% and 91%, respectively, were successfully matched with unexposed controls. Both NTM-PD and NTM-PI were associated with higher rates of death for all species combined and for most individual species. Compared with NTM-PI, NTM-PD was associated with higher death rates for all species combined, Mycobacterium avium complex, and M. xenopi. NTM-PD and NTM-PI were significantly associated with death, NTM-PD more so than NTM-PI.
Molecular, Spatial, and Field Epidemiology Suggesting TB Transmission in Community, Not Hospital, Gaborone, Botswana
D. Surie et al.View Abstract
During 2012–2015, 10 of 24 patients infected with matching genotypes of Mycobacterium tuberculosis received care at the same hospital in Gaborone, Botswana. Nosocomial transmission was initially suspected, but we discovered plausible sites of community transmission for 20 (95%) of 21 interviewed patients. Active case-finding at these sites could halt ongoing transmission.
Rhodococcus Infection in Solid Organ and Hematopoietic Stem Cell Transplant Recipients
P. Vergidis et al.View Abstract
We conducted a case–control study of 18 US transplant recipients with Rhodococcus infection and 36 matched controls. The predominant types of infection were pneumonia and bacteremia. Diabetes mellitus and recent opportunistic infection were independently associated with disease. Outcomes were generally favorable except for 1 relapse and 1 death.
Zoonotic Transmission of mcr-1 Colistin Resistance Gene from Small-Scale Poultry Farms, Vietnam
N. Trung et al.View Abstract
We investigated the consequences of colistin use in backyard chicken farms in Vietnam by examining the prevalence of mcr-1 in fecal samples from chickens and humans. Detection of mcr-1–carrying bacteria in chicken samples was associated with colistin use and detection in human samples with exposure to mcr-1–positive chickens.
Genetically Diverse Filoviruses in Rousettus and Eonycteris spp. Bats, China, 2009 and 2015
X. Yang et al.View Abstract
Genetically divergent filoviruses detected in Rousettus and Eonycteris spp. bats in China exhibited 61%–99% nt identity with reported filoviruses, based on partial replicase sequences, and they demonstrated lung tropism. Co-infection with 4 different filoviruses was found in 1 bat. These results demonstrate that fruit bats are key reservoirs of filoviruses.
Likely Autochthonous Transmission of Trypanosoma cruzi to Humans, South Central Texas, USA
S. M. Gunter et al.View AbstractCite This Article
Chagas disease, caused by Trypanosoma cruzi, is a major neglected tropical disease affecting the Americas. The epidemiology of this disease in the United States is incomplete. We report evidence of likely autochthonous vectorborne transmission of T. cruzi and health outcomes in T. cruzi–seropositive blood donors in south central Texas, USA.
EID Gunter SM, Murray KO, Gorchakov R, Beddard R, Rossmann SN, Montgomery SP, et al. Likely Autochthonous Transmission of Trypanosoma cruzi to Humans, South Central Texas, USA. Emerg Infect Dis. 2017;23(3):494-497. https://dx.doi.org/10.3201/eid2303.161157 AMA Gunter SM, Murray KO, Gorchakov R, et al. Likely Autochthonous Transmission of Trypanosoma cruzi to Humans, South Central Texas, USA. Emerging Infectious Diseases. 2017;23(3):494-497. doi:10.3201/eid2303.161157. APA Gunter, S. M., Murray, K. O., Gorchakov, R., Beddard, R., Rossmann, S. N., Montgomery, S. P....Garcia, M. N. (2017). Likely Autochthonous Transmission of Trypanosoma cruzi to Humans, South Central Texas, USA. Emerging Infectious Diseases, 23(3), 494-497. https://dx.doi.org/10.3201/eid2303.161157.
Outbreaks of Disease Associated with Food Imported into the United States, 1996–2014
PDF Version [PDF - 989 KB - 3 pages]
L. Gould et al.View AbstractCite This Article
The proportion of US food that is imported is increasing; most seafood and half of fruits are imported. We identified a small but increasing number of foodborne disease outbreaks associated with imported foods, most commonly fish and produce. New outbreak investigation tools and federal regulatory authority are key to maintaining food safety.
EID Gould L, Kline J, Monahan C, Vierk K. Outbreaks of Disease Associated with Food Imported into the United States, 1996–2014. Emerg Infect Dis. 2017;23(3):525-528. https://dx.doi.org/10.3201/eid2303.161462 AMA Gould L, Kline J, Monahan C, et al. Outbreaks of Disease Associated with Food Imported into the United States, 1996–2014. Emerging Infectious Diseases. 2017;23(3):525-528. doi:10.3201/eid2303.161462. APA Gould, L., Kline, J., Monahan, C., & Vierk, K. (2017). Outbreaks of Disease Associated with Food Imported into the United States, 1996–2014. Emerging Infectious Diseases, 23(3), 525-528. https://dx.doi.org/10.3201/eid2303.161462.
Pneumonic Plague Transmission, Moramanga, Madagascar, 2015
B. Ramasindrazana et al.View Abstract
During a pneumonic plague outbreak in Moramanga, Madagascar, we identified 4 confirmed, 1 presumptive, and 9 suspected plague case-patients. Human-to-human transmission among close contacts was high (reproductive number 1.44) and the case fatality rate was 71%. Phylogenetic analysis showed that the Yersinia pestis isolates belonged to group q3, different from the previous outbreak.
Mycobacterium chimaera in Heater–Cooler Units in Denmark Related to Isolates from the United States and United Kingdom
E. Svensson et al.View Abstract
Mycobacterium chimaera was present at high rates (>80%) in heater–cooler units (HCUs) from all 5 thoracic surgery departments in Denmark. Isolates were clonal to HCU-associated isolates from the United States (including some from patients) and United Kingdom. However, M. chimaera from 2 brands of HCU were genetically distinct.
pncA Gene Mutations Associated with Pyrazinamide Resistance in Drug-Resistant Tuberculosis, South Africa and Georgia
S. Allana et al.View Abstract
Although pyrazinamide is commonly used for tuberculosis treatment, drug-susceptibility testing is not routinely available. We found polymorphisms in the pncA gene for 70% of multidrug-resistant and 96% of extensively drug-resistant Mycobacterium tuberculosis isolates from South Africa and Georgia. Assessment of pyrazinamide susceptibility may be prudent before using it in regimens for drug-resistant tuberculosis.
Mycobacterium tuberculosis Infection among Asian Elephants in Captivity
G. Simpson et al.View Abstract
Although awareness of tuberculosis among captive elephants is increasing, antituberculosis therapy for these animals is not standardized. We describe Mycobacterium tuberculosis transmission between captive elephants based on whole genome analysis and report a successful combination treatment. Infection control protocols and careful monitoring of treatment of captive elephants with tuberculosis are warranted.
Variegated Squirrel Bornavirus 1 in Squirrels, Germany and the Netherlands
K. Schlottau et al.View Abstract
We screened squirrels in Germany and the Netherlands for the novel zoonotic variegated squirrel bornavirus 1 (VSBV-1). The detection of VSBV-1 in 11 squirrels indicates a considerable risk for transmission to humans handling those animals. Therefore, squirrels in contact with humans should routinely be tested for VSBV-1.
Increase in Tuberculosis Cases among Prisoners, Brazil, 2009–2014
P. M. Bourdillon et al.View Abstract
During 2009–2014, incarceration rates in Brazil rose 34%, and tuberculosis (TB) cases among prisoners rose 28.8%. The proportion of national TB cases that occurred among prisoners increased from 6.2% to 8.4% overall and from 19.3% to 25.6% among men 20–29 years of age.
Molecular Evidence of Drug Resistance in Asymptomatic Malaria Infections, Myanmar, 2015
M. Nyunt et al.View Abstract
Artemisinin resistance containment in Myanmar was initiated in 2011 after artemisinin-resistant Plasmodium falciparum malaria was reported. Molecular evidence suggests that asymptomatic malaria infections harboring drug resistance genes are present among residents of the Myanmar artemisinin resistance containment zone. This evidence supports efforts to eliminate these hidden infections.
Disseminated Nontuberculous Mycobacteria in HIV-Infected Patients, Oregon, USA, 2007–2012
C. D. Varley et al.View Abstract
We determined disseminated nontuberculous mycobacteria incidence in the HIV-infected population of Oregon, USA, during 2007–2012 by using statewide laboratory surveillance. We identified 37 disseminated nontuberculous mycobacteria cases among 7,349 patients with median annual incidence of 110/100,000 HIV person-years and the highest incidence in those with CD4 counts <50 cells/mm3 (5,300/100,000 person-years).
Mycobacterium tuberculosis in Wild Asian Elephants, Southern India
A. Zachariah et al.View Abstract
We tested 3 wild Asian elephants (Elephas maximus) in southern India and confirmed infection with Mycobacterium tuberculosis, an obligate human pathogen, by PCR and genetic sequencing. Our results indicate that tuberculosis may be spilling over from humans (reverse zoonosis) and emerging in wild elephants.
Research Letters
Imported Leptospira licerasiae Infection in Traveler Returning to Japan from Brazil
M. Tsuboi et al.View Abstract
We describe a case of intermediate leptospirosis resulting from Leptospira licerasiae infection in a traveler returning to Japan from Brazil. Intermediate leptospirosis should be included in the differential diagnosis for travelers with fever returning from South America. This case highlights the need for strategies that detect pathogenic and intermediate Leptospira species.
Autochthonous Outbreak and Expansion of Canine Visceral Leishmaniasis, Uruguay
D. Satragno et al.View Abstract
We report an outbreak of canine visceral leishmaniasis in Uruguay. Blood specimens from 11/45 dogs tested positive for Leishmania spp. Specimens of Lutzomyia longipalpis sand flies were captured; typing revealed Leishmania infantum. Our findings document an expansion of visceral leishmaniasis to southern South America and risk for vectorborne transmission to humans.
Worldwide Endemicity of a Multidrug-Resistant Staphylococcus capitis Clone Involved in Neonatal Sepsis
M. Butin et al.View Abstract
A multidrug-resistant Staphylococcus capitis clone, NRCS-A, has been isolated from neonatal intensive care units in 17 countries throughout the world. S. capitis NRCS-A prevalence is high in some neonatal intensive care units in France. These data highlight the worldwide endemicity and epidemiologic relevance of this multidrug-resistant, coagulase-negative staphylococci clone.
Two Cases of Neisseria meningitidis Proctitis in HIV-Positive Men who Have Sex with Men
J. Gutierrez-Fernandez et al.View Abstract
We report 2 cases from Spain of infectious proctitis caused by Neisseria meningitidis in HIV-positive men who have sex with men. Genetic characterization of the isolates showed that they are unusual strains not found in other more frequent meningococcal locations. This finding suggests an association between specific strains and anogenital tract colonization.
Association of Diabetes and Tuberculosis Disease among US-Bound Adult Refugees, 2009–2014
S. R. Benoit et al.View Abstract
Diabetes is associated with an increased risk for active tuberculosis (TB) disease. We conducted a case–control study and found a significant association between diabetes and active TB disease among US-bound refugees. These findings underscore the value of collaborative management of both diseases.
Potentially Zoonotic Bartonella in Bats from France and Spain
M. J. Stuckey et al.View Abstract
We detected Bartonella in 11 of 109 insectivorous bats from France and 1 of 26 bats from Spain. These genetic variants are closely related to bat-associated Bartonella described in Finland and the United Kingdom and to B. mayotimonensis, the agent of a human endocarditis case in the United States.
Molecular Verification of New World Mansonella perstans Parasitemias
L. Tavares da Silva et al.View Abstract
We obtained ribosomal and mitochondrial DNA sequences from residents of Amazonas state, Brazil, with Mansonella parasitemias. Phylogenetic analysis of these sequences confirm that M. ozzardi and M. perstans parasites occur in sympatry and reveal the close relationship between M. perstans in Africa and Brazil, providing insights into the parasite's New World origins.
Successful Treatment of Human Plague with Oral Ciprofloxacin
PDF Version [PDF - 645 KB - 3 pages]
T. Apangu et al.View AbstractCite This Article
The US Food and Drug Administration recently approved ciprofloxacin for treatment of plague (Yersina pestis infection) based on animal studies. Published evidence of efficacy in humans is sparse. We report 5 cases of culture-confirmed human plague treated successfully with oral ciprofloxacin, including 1 case of pneumonic plague.
EID Apangu T, Griffith K, Abaru J, Candini G, Apio H, Okoth F, et al. Successful Treatment of Human Plague with Oral Ciprofloxacin. Emerg Infect Dis. 2017;23(3):553-555. https://dx.doi.org/10.3201/eid2303.161212 AMA Apangu T, Griffith K, Abaru J, et al. Successful Treatment of Human Plague with Oral Ciprofloxacin. Emerging Infectious Diseases. 2017;23(3):553-555. doi:10.3201/eid2303.161212. APA Apangu, T., Griffith, K., Abaru, J., Candini, G., Apio, H., Okoth, F....Mead, P. (2017). Successful Treatment of Human Plague with Oral Ciprofloxacin. Emerging Infectious Diseases, 23(3), 553-555. https://dx.doi.org/10.3201/eid2303.161212.
Serologic Evidence for MERS-CoV Infection in Dromedary Camels, Punjab, Pakistan, 2012–2015
M. Saqib et al.View Abstract
Dromedary camels from Africa and Arabia are an established source for zoonotic Middle East respiratory syndrome coronavirus (MERS-CoV) infection among humans. In Pakistan, we found specific neutralizing antibodies in samples from 39.5% of 565 dromedaries, documenting significant expansion of the enzootic range of MERS-CoV to Asia.
Fungal Contamination of Methylprednisolone Causing Recurrent Lumbosacral Intradural Abscess
J. J. Renfrow et al.View Abstract
Fungal meningitis transmitted through injections of methylprednisolone contaminated with Exserohilum rostratum affected 753 persons and caused 61 deaths in the United States in 2012. We report a case of infection recurrence after 24-months with the unique manifestation of an intradural fungal abscess. Fungal disease should remain on the differential diagnosis list for previously exposed patients.
Mycobacterium tuberculosis Infection in Free-Roaming Wild Asian Elephant
B. Chandranaik et al.View Abstract
Postmortem examination of a wild Asian elephant at Rajiv Gandhi National Park, India, revealed nodular lesions, granulomas with central caseation, and acid-fast bacilli in the lungs. PCR and nucleotide sequencing confirmed the presence of Mycobacterium tuberculosis. This study indicates that wild elephants can harbor M. tuberculosis that can become fatal.
Mycobacterium bovis in a Free-Ranging Black Rhinoceros, Kruger National Park, South Africa, 2016
M. A. Miller et al.View SummaryView Abstract
Mycobacterium bovis in a Free-Ranging Black Rhinoceros, Kruger National Park, South Africa, 2016
In 2016, an emaciated black rhinoceros (Diceros bicornis) was found in Kruger National Park, South Africa. An interferon-γ response was detected against mycobacterial antigens, and lung tissue was positive for Mycobacterium bovis. This case highlights the risk that tuberculosis presents to rhinoceros in M. bovis–endemic areas.
Zika Virus Vector Competency of Mosquitoes, Gulf Coast, United States
C. E. Hart et al.View Abstract
Zika virus has recently spread throughout the Americas. Although Aedes aegypti mosquitoes are considered the primary vector, Culex quinquefasciatus and mosquitoes of other species may also be vectors. We tested Cx. quinquefasciatus and Ae. taeniorhynchus mosquitoes from the US Gulf Coast; both were refractory to infection and incapable of transmission.
About the Cover
Keeping It in the Family: the Childhood Burden of Tuberculosis
T. Chorba and J. Jereb
Etymologia: Mycobacterium chimaera
R. Henry
Volume 23, Number 3 - March 2017
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Related Information
Additional Resources
- Page created: February 15, 2017
- Page last updated: February 15, 2017
- Page last reviewed: February 15, 2017
- Centers for Disease Control and Prevention,
National Center for Emerging and Zoonotic Infectious Diseases (NCEZID)
Office of the Director (OD)


text:
Question about JVC KD-AVX1 Car DVD Player
Posted by apaxs on
There may be dirt on the laser lens. Maybe there is something mechanicaly worn that is causing the laser to not properly track the DVD information on the disk.
How to clean a DVD lense from eHow:
After cleaning the DVD lens, if the problem still exists, then the DVD player will require proper service. If it is a low to medium cost unit, or if it is more than about 3 to 4 years old, then it may not be worth to service.
Jerry G.
Posted on Apr 19, 2008
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HTML 5 Application Development Class
2 Day HTML 5 Application Development Training
What: This is a 2 day HTML5 training class that begins at 9:00 AM and ends at 5:00 PM each day. There is no coding or programming experience required to attend this class. A general understanding of web page layout is helpful however not necessary. What is necessary is a desire to learn HTML5.
Description: Get the insight into HTML5 Application Development with this 2 day it training course. The class begins at 9:00 AM with coffee as students settle in; this helps tremendously with developing a comfortable environment for the student. You (the attendee) don't have to worry about getting coffee in the morning; show up for class and we will take care of your needs in class (lunch is included as well).
The class begins with an introduction to HTML5, Document Object Model and an overview of JavaScript. Following this, Event Handling mechanism is explained in detail. This gives foundation for the class. Following this Forms, Audio and Video APIs are explained in detail. The morning session concludes with exercises that cover AJAX, HTML Forms, Video and Audio API.
Following lunch we start out with HTML5 Canvas. Canvas API is explained in detail. Following this, a couple of HTML5 Canvas/Graphics libraries are explained in detail. Students will work on building an HTML5 Applications from scratch using Canvas, Canvas Libraries that integrates Canvas with Audio, Video and Drag and Drop APIs. This concludes the session for first day.
Day 2 begins with fresh coffee at 9:00 AM. Morning session starts with Communication API. This follows detailed explanation of AJAX, XMLHttpRequest and Cross-Domain Messaging. Then we will cover Web Workers, Web Sockets and GeoLocation APIs. This session concludes with hands-on exercises using these topics.
Following lunch, we will cover storage API. This covers in detail how to store HTML5 data on local machine and in remote cloud. Following this, how to develop and configure offline applications. Then WebGL is explained in detail. The session concludes with the review of topics covered in the class and how to improve performance of HTML5 applications.
This is a 2 day it training course that requires a commitment from 9:00 AM to 5:00 PM on both days. Morning coffee and Lunch are included for both days. The class size is small so that individualized attention can be paid to all the students. Many opportunities for Q&A are offered to the students. The instructor for this class is an experienced programmer/instructor. We have been successfully teaching this class since 2011.
- Introduction to HTML5
- Review of DOM and JavaScript
- Event Handling in HTML5
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- Video and Audio API
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-HTML5 Graphic Libraries
-Developing Canvas Applications using Custom Libraries
-Communication API
-XMLHttpRequest and Cross-Domain Messaging
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-Local Storage API
-Storage over Cloud
-Introduction to WebGL
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-Optimizing HTML5 Applications
2 Day IT Training - HTML5 App Development Class
Monday and Tuesday - May 14th and 15th (9:00 AM - 5:00 PM - 2 days)
Executive Hotel Vintage Court
650 Bush Street, San Francisco, CA
Conveniently located close to 2 BART Stations
2 Blocks from Union Square
Lunch included on both days
Contact: [masked]
- HTML5 offers faster image downloads, especially for mobile users
- HTML5 offers improved SEO
- HTML5 offers Sophisticated animation effects
- HTML5 offers Easier Web and Mobile App Development
- BBC is turning towards HTML5 for application development
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- HTML5 is one of the most desired skills by employer
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A. Please sign up on eventbrite: http://startupsaturdays.eventbrite.com/
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C. If you have an employer sponsored education program then please contact us at: [masked]
We can work with various reimbursement and employer sponsored educational programs.
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text:
Manchester City are confident of securing Kolo Toure's transfer from Arsenal by the end of this week in a move which would take manager Mark Hughes' spending this summer close to the £100million mark.
Talks between City and Arsenal are continuing and Gunners manager Arsene Wenger has conceded the Ivory Coast defender could be leaving.
It is understood City are very hopeful of wrapping up a deal for the 28-year-old, for a sum in the region of £15million, before the end of the week.
Hughes has already spent £80.5million, including £25million on Emmanuel Adebayor from Arsenal as well as the costly signings of Roque Santa Cruz, Carlos Tevez and Gareth Barry. He is thought to also be keen on Everton defender Joleon Lescott.
Wenger has insisted however that a deal for Toure, who played for Arsenal last night in a pre-season friendly in Hungary, is not definite.
Wenger told Arsenal TV: "We will see what's happening in the next 24 hours, nothing is decided yet.
"We have seven centre-backs and I am in the position where I have to play some in midfield but of course Kolo is a very good player and we will see what will happen in the next 24 hours."
City's spending could see them in direct competition with Arsenal for a Champions League place next season.
So far Wenger has made just one signing, central defender Thomas Vermaelen from Ajax, but he hinted that there will more arrivals before the transfer window closes.
Wenger added: "I am more focused on getting everybody fit for the start of the season but we are looking at opportunities as well, there are still some pre-season games to see what we really need.
"When the time comes we will do something."Reuse content


text:
Ana's Profile
I live and work in Houston as a graphic designer. I usually design logos, websites and other odds and ends for small businesses. Weddings have always been such sources of inspiration for me (I even wanted to be a wedding planner at one point!). So designing wedding invitations was something that just seemed perfect. I love creating unique, custom looks for people to make their special day shine!
Visit my shop: http://www.etsy.com/shop/goldfoxpaper
Read my blog: http://www.goldfoxpaper.blogspot.com
- Female
- Joined April 29, 2012
Favorite materials
- Ana
- Houston, TX, United States


text:
And just for laughs, here is my son after I carried him from one end to other, lol ImageUploadedByThe Bub Hub1368185673.359757.jpg
And just for laughs, here is my son after I carried him from one end to other, lol ImageUploadedByThe Bub Hub1368185673.359757.jpg
Ashram (11-05-2013),Little Miss Muffet (11-05-2013),RobinSparkles (12-05-2013),VicPark (10-05-2013)
Ahhh the terrible 2s, gotta love em NOT!
DS did it pretty bad from about 27 months then was ok a little after 3
DD is 2 in a few weeks and thus far shes fine. I say we're leaving she quickly follows in tow. Not saying it won't ever happen that would be dreaming lol but totally feel you OP as ds was a massive tanty thrower
Me(21) DH(25) DS(4) DD(2) +Tank (mastiff x)
Sent from a magical mobile bubhub device in a galaxy far far away
My almost 5 year old still has tantrums
DS has at least a tantrum a day - he's 16 months. The coming years are very frightening for me. I actually had a man in the supermarket tell me how serious my DS was, whilst DS was staring him down from the trolley. DS seems to wake up grumpy these days, literally threw his sippy cup on the floor first things this morning.
What I think may have helped a little bit is dd1 starting to grasp the concept of things being open or closed. So we have to leave because it's closing time (yep even the park "closes" ) and it can help with morning dawdling because we have to hurry and get to wherever before it "closes". Sometimes it works sometimes it doesn't.
So unless I were to give in, there is no reasoning. And I refuse to give in and raise a spoilt brat.
I used to look/stare/judge others but now I get how hard and how physically strong they can be to restrain without using hitting/smacking etc.
Now I sympathize, it's not easy.
I travelled Perth/Sydney 4 weeks ago with my 2 boys alone and ds2 was a noghtmare. He headbuts, bites, pinches. Was I embarrased? I guess a bit but I really just feel sad for my kid coz he won't calm down for hours .
i give her ample warnings when it's coming up time to leave...."5 more minutes and it's time to go home for lunch..." or "one more slide and then we have to go...." or "one last swing....." i bribe with food "do you want a happy meal on the way home?...then we have to say goodbye to the park".
I ask her to help me find our car and she can hold my keys if she comes with me now (she knows what our car looks like).
I havent tried "the park is closing" thats a good one!
As someone else said, i can do all this till the cows come home. toddlers are really really stubborn little things, so ive learnt. It keeps going till the are 3? god help me.
Oh hugs! DS is 2 and this sort of tantrums happens on a daily basis. Few times a day.
I peeled his mandarin; he throws a tanty.
I opened his yogurt, he screams
I ate his chip, he cries
The list goes on, it seems he screams and cries over anything and everything that doesn't goes his way. I usually ignore him until he's calm then I would try to talk to him. Or I would try to distract him.
Da is 13m and he has started tantrums! Throws himself on the ground just like the picture above! Just lays there flat and cries. I try and figure out what caused it but its hard. I think he wants picking up constantly. I try give food and he throws it and more tanty!
So I'm dreading the 2s-3s!! I think I will just stand there and wait for him to give in. Just calmly tell him I will wait until he is finished. Wonder how long I will be standing in a shopping isle for!!!
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text:
Chainsaw - is a tool that significantly accelerates and facilitates the process of processing and cutting wood.
With proper care chainsaw service life can reach several years.
Types of chainsaws
Before buying a chainsaw, you need tothe choice between the three main types of instruments: home, semi-professional and professional. The first of these is the best suited for the most simple tasks such as firewood or treatment of dead trees, and are designed to save your strength, as an alternative axes and saws. Chainsaws other two types are similar in their characteristics. They can saw even the most strong and powerful trees, and features of their designs allow less tired at work such chainsaws. The difference between the professional and semi tools is that the former can be used for more than 10 hours and the second at the same time comes to an end after 4 hours of operation.
The difference in working hours of professional and semi-professional chainsaw affects the value of these instruments - the first will cost substantially more expensive than the latter.
For daily needs in the suburban area can bebuy a chainsaw special kind - one-handed. It is small in size and modest weight, so that not only can be used for pruning trees or large decorative plants, but also useful while fishing or hunting. A good choice of such a lightweight and compact chainsaw is even in the event that most of the work must be performed at a height of at arm's length - so they will be less tired.
Features chainsaws
Power chainsaw - this is one of the keycharacteristics of the tool. It depends on the power directly chainsaw ability to withstand high loads and cope with durable materials. For active work, this figure should be at least 2-3 kW, the domestic saws such a serious power unnecessarily.
The difference between the types of saws could alsois a method of struggle against kickback, which can occur when docking with the wood surface. The tools of modern stamps it uses a special shield that covers one side of the web chainsaw or inertia braking system - about the kickback tool with this type of protection is simply stall.
Inertia braking system more reliable and safer, which is why the majority of chainsaws equipped with just such protection.
Strong vibration - this is the most serious flawchain saws, which is particularly well manifested in continuous operation. Therefore, you should choose the brand of chain saws, which is equipped with anti-vibration system. It reduces the load on the hand, helping them less tired even after several hours of operation tools.


text:
Annu Shetty Naik's Shop
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A Vision of Yemen
Regard sur le Yemen
Introduction by Nicole de Pontcharra
Photographs by Sheikh Hassan Al Thani
Format: Hardback
Normal Price: $105.00
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Availability: Available, ships in 7-10 days
Vision of Yemen by Nicole de Pontcharra
Book DescriptionA socially committed Arab photographer, Sheikh Hassan Al Thani is a tireless explorer of the history of southern Arabia. He does not see Yemen through the eyes of a naive tourist, but as an artist seeking to capture its emotional charge. A curious observer who is well acquainted with his subject, he photographs the footprints of this civilisation of writing, the roads of incense and coffee, the columns of the temple of the Queen of Sheba, the ruins of the Mocha tower, oases, arid expanses, and palm trees, all while pondering the country's future.
Buy Vision of Yemen book by Nicole de Pontcharra from Australia's Online Bookstore, Boomerang Books.
Book DetailsISBN: 9788876248719
(280mm x 280mm x 23mm)
Pages: 216
Imprint: Skira
Publisher: Skira
Publish Date: 19-Feb-2007
Country of Publication: Italy
» Have you read this book? We'd like to know what you think about it - write a review about Vision of Yemen book by Nicole de Pontcharra and you'll earn 50c in Boomerang Bucks loyalty dollars (you must be a member - it's free to sign up!)
Author Biography - Nicole de Pontcharra
Nicole de Pontcharra-Postnikowa, a French writer of Russian origins, publishes written works while also creating artistic and cultural events (exhibitions, symposia, journeys, book shows, etc.) focussed on exploring two different realms: the countries of the Arab world, and the countries of the East. She is the author of numerous collections of poetry and prefaces to exhibition catalogues and art books.
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Not a member yet? Join now
Hi there,
I have a job offer in Abu Dhabi that would see me move from Sydney, Australia.
I work in Digital Marketing and Social media and the offer is on par with what I can earn in Australia so I don't have the financial incentive getting me over there. I also have a partner who is concerned about coming over with me because he does not have a job and I cannot sponsor him.
I am looking for advice from other people in my situation as to how you found it when you first arrived, what was the hardest part and how did you adapt?
Also, where should I live?
Thanks in advance.


text:
This collection of frames features a lightly antiqued silver leaf finish with a matte black liner. Photos are surrounded by oatmeal linen mats. May be hung horizontal or vertical. Holds photo sizes:11-4x6, 1-8x10, 4-5x7 Frame sizes:13x40, 15x17, 11x27, 2-
The Alternative Wall Decor Massena Photo Collage Set of 7 by Uttermost at Becker Furniture World in the Twin Cities, Minneapolis, St. Paul, Minnesota area. Product availability may vary. Contact us for the most current availability on this product.
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Oakwood Manor Motor Lodge
610 Massey Road Mangere, Mangere 20222.5 out of 5.0
Situated near the airport, this motel is 2.7 mi (4.3 km) from Villa Maria Estate and within 6 mi (10 km) of Butterfly Creek …
ibis budget Auckland Airport
2 Leonard Isitt Drive, Auckland Airport 21503.0 out of 5.0
Situated in Auckland Airport, this hotel is 0.5 mi (0.7 km) from Butterfly Creek and 2.4 mi (3.9 km) from Villa Maria Estate. …
Novotel Auckland Airport
Ray Emery Drive, Auckland Airport 20224.5 out of 5.0
Located in Auckland Airport, this family-friendly hotel is 0.8 mi (1.3 km) from Butterfly Creek, and within 6 mi (10 km) of …
Best Western Ellerslie International
2 Wilkinson Road, Ellerslie, Auckland 10514.0 out of 5.0
Located in Ellerslie, this hotel is 1.2 mi (2 km) from Ellerslie Racecourse and 2.8 mi (4.5 km) from One Tree Hill Domain. …
Mt Eden Motel
47 Balmoral Road, Auckland 10242.5 out of 5.0
Located in Mount Eden, this motel is 0.8 mi (1.3 km) from Clip 'n Climb and within 3 mi (5 km) of Mt. Eden and University o …
Royal Park Lodge
159-161 Great South Road, Auckland 10514.0 out of 5.0
Located in Greenlane, this motel is 0.8 mi (1.3 km) from Mercy Ascot Hospital and within 3 mi (5 km) of Mt. Eden and One Tree …
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- Jet Park Hotel & Conference Centre
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text:
So up to now we have figured out different things we can do with Wordpress, mainly adding PoLib codes for the red borders. That's something we got pretty quick, though adding polls has been something that we never got an answer for until now thanks to Cain-IGN (give her a follow and thanks).
You do so by switching to HTML (You HAVE to add it to HTML) and adding this code where you want it to appear:
{widget path="global/page/polldaddy" parameters="id=6910878&question=Vote!"}
^^^replace "{ }" with "[ ]"
The part that you have to replace is the code (highlighted in red).
Create a Polldaddy account and link it to your Wordpress account. Then create a poll to get the code.
Green Lantern(Simon Baz)


text:
Hi All
I will need to put my daughter in a holiday program over the holidays due to work. I just got the forms today and it costs $46 per day and some of the days they have excursions so its an extra $20 on those days. My question is, if I get the CCB, does that apply to holiday programs at all? $46 a day is alot and if the CCB doesnt apply I dont think I will be able to afford her going.
Any help would be great