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- //Home
- //Music
- //Reviews
- //Andrew Pekler
Is This Music?
There are albums you can describe as "difficult listening", and then there are albums where it's difficult to decide whether they qualify as music at all. The latter's the case with Pekler's third album, Strings + Feedback; if "music" requires elements like modality, melody, and harmony, then this ain't it. Pekler's previous work has been described as Tortoise-meets-Pole, but Strings + Feedback makes those "difficult" acts sound like early Beach Boys by comparison.
Not much can arouse a critic's—or any music lover's—self-doubt like a high-minded, highly unorthodox album such as this: Am I insufficiently familiar with the complex mathematical equations behind the compositions? Has all the pigeonholing and cross-referencing left me unprepared to deal with this? Or am I just too closed-minded to "get it"?. One may ask these difficult questions before considering the other option: This isn't music at all; it's high-minded bullshit.
Andrew Pekler
Strings + Feedback
US: 27 Sep 2005
UK: 26 Sep 2005
Maybe all this would make a little more sense if you knew how Strings + Feedback actually sounds. Well, the title isn't too far off the mark, actually. Pekler pokes and prods his analog synthesizers until they yield a series of eerie, disturbing tones and bursts of white noise. If you've ever gone to your public library and checked out dust-covered albums (they do still have LPs at the library, don't they?) of the experimental electronic recordings made in the 1950s, you have an idea of what Pekler's getting at. For all synthesizers' myriad uses and ranges of sound these days, those early recordings present the instrument as a creepy, creepy noise-making machine.
Or you could just do this: imagine Radiohead's "National Anthem" without the guitars, bass, drums, or horns. Then imagine it going on for 40 minutes.
To be fair, "Ogonook" does have staccato synth-strings playing a couple recognizable chords, and "Organist" features an organ droning away and again playing something almost harmonic. "Mirrorise" uses that earliest of electronic instruments, the theremin, in an old-science-fiction-movie way. But by the time they reach their conclusions, even these tracks are overwhelmed by overdriven oscillators and general freakiness.
You could say, then, that Strings + Feedback does achieve and sustain a certain mood and feeling, however unpleasant. Maybe that's enough to make it music. It could be a masterpiece that some ears are just not sophisticated enough to decode. Or it could be your younger brother playing with his Vintage Keys program for the very first time. The truth is, you probably won't want to listen to it long enough to be able to decide.
We all know how critical it is to keep independent voices alive and strong online. Please consider a donation to support our work as an independent publisher devoted to the arts and humanities. Your donation will help PopMatters stay viable through these changing and challenging times where advertising no longer covers our costs. We need your help to keep PopMatters publishing. Thank you.
Big Bad Voodoo Daddy "Dinah" (audio) (premiere) // Music
Rachel Kilgour 'Rabbit in the Road' (album) (premiere) // Music
Depeche Mode "Where's the Revolution" (Singles Going Steady) // Music
Beth Bombara "Sweet Time" (audio) (premiere) // Music
20 Questions: Nashville Singer-Songwriter Natalie Hemby
// Sound Affects
"Natalie Hemby's Puxico is a standout debut from a songwriter who has been behind the scenes for over a decade.READ the article


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Click on the "Convert & Download Video + MP3" button to start the video conversion. After the video conversion is finished, you can download the converted video in the formats MP4 or 3GP (for mobile phones) or you can download the converted audio as a MP3 music file. This online service is completely for free.
Hmm, he-he Oh, hey Doesn't matter (It doesn't matter) Doesn't matter at all Doesn't matter what your friends are telling you Doesn't matter what my family's ...
DMCA: Are you the owner of this convertable material and do you want to disable the conversion of your media on clip.dj? Then you can request a conversion block for this video.236
Music video by Janet Jackson performing "Doesn't Really Matter" (C) 2000 Def Jam Recordings.
Janet Jackson - Doesn't Really Matter Remix - Jonathan Peters Club Edit.
Janet sings Live at the 2009 American Music Awards - HD!
Nutty Professor II: The Klumps OST Soundtrack album by Various Released: July 11, 2000 Label: Def Jam Recordings.
Janet Jackson performs Doesn't Really Matter on Top of the Pops in 2000.

subset: commoncrawl


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Alternative websites for 4505meats.com
1. Result for 4505meats.com
Aug 28, 2013 ... 4505 Meats is taking over 705 Divisadero, a.k.a. the location that was most recently known as Da Pitt. Ryan Farr is plotting to revamp and ...
Alternative for insidescoopsf.sfgate.com
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Serving Petaluma Evening Farmer's Market, San Francisco Ferry Plaza, San Rafael Civic Center and Temescal in Oakland.
Alternative for pizzapolitana.com
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Whole Beast Butchery: The Complete Visual Guide to Beef, Lamb, and Pork [ Ryan Farr, Brigit Binns, Ed Anderson] on Amazon.com. *FREE* shipping on ...
Alternative for amazon.com
Alternative for amazon.com
The Best Meat Shops in San Francisco on Yelp. Read about places like: Guerra Quality Meats, Mission Market Fish & Poultry, Drewes Meats, Little City Market, ...
Alternative for yelp.com
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Hey Meat Lovers, don't forget we're still raising funds for Mo' Magic this month! All funds raised are going towards creating low cost quality summer programming ...
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The CamRade TPBI ROLL tripodBag (Gray) is a 1000 denier Cordura nylon bag designed to carry and protect a tripod up to 37" long. The bag has reinforced plastic sides with a fully padded interior and a nylon lining. There is an interior full length pocket with zipper. It is transported by 2 carrying handles, a flat strap handle, a removable, adjustable shoulder strap with pad, a backpack harness that stores under a touch fastener flap and built-on wheels.
|Tripod up to 37" long
|Carrying/Transport Options:
|Two handles Flat strap handle Shoulder strap with pad Backpack harness Built-in Wheels
|Exterior Dimensions (L x W x H):
|980 x 210 x 250 mm 38.5 x 8.3 x 10 inch
|Interior Dimensions (L x W x H):
|950 x 180 x 200 mm 37.4 x 7 x 8 inch
|Exterior: 1000 denier Cordura nylon Interior: Fully padded Interior: 3.0mm plastic sides Interior: Nylon lining
|Type of Closure:
|2.8 Kg 6.2 lb
|CamRade TripodBag II Roll Tripod Case with Built-in Wheels
|CamRade TripodBag I Tripod Case
|CamRade TripodBag II Tripod Case


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7 Diamonds
'Escape' Woven Shirt
Product not available
Have questions?
Chat with us or call 1.888.282.6060.
HideDetails & Care
Contrast trim, decorative topstitching and panel detailing at the shoulders accent a short-sleeve shirt patterned in retro-inspired plaid and finished with multiple pockets.
- Approx. length from shoulder: 31".
- Measurements taken from size Medium and may vary slightly by size.
- Button-flap pockets; chest welt pocket.
- Cotton; machine wash.
- By 7 Diamonds; imported.
- The Rail.


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- Product Details
- Fabric Estimator
- Rewards
Spice up your style with this exotic applique. Here we have a 4.5" champagne beaded rhinestone applique. This exciting and fun piece can add a kick to any application. This applique has beige, cream and champagne beads that compliment each other in this intricately placed design. This is perfect for stylistic touches to a beach hat or denim jeans.
Color: Champagne/Cream
Width: 4.5" X 3.5"
Country: INDIA
PLEASE NOTE: The above numbers are estimations only. Please take into account garment size, lining and fabric width.


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Great Bang-for-your-buck Keyboard
The Casio CTK-3200 portable keyboard is an ideal first keyboard. With 400 great sounds, an intuitive interface, and easy-to-use arranger functions, the CTK-3200 makes learning and composing music fun and exciting. Polish your skills while enjoying the CTK-3200's 61 touch-sensitive keys and impressive built-in features - which include 110 songs, 150 rhythms, a sampling function, a pitch bend wheel, and a highly effective learning system. You also get onboard speakers and an audio input for connecting a CD or MP3 player, so you can play along with your favorite tunes. Ignite your passion for music with the Casio CTK-3200.Casio CTK-3200 Portable Keyboard at a Glance:
- Never run out of inspiring sounds
- Built-in lessons and play-along songs
- Cool sound sampling feature
The Casio CTK-3200 includes an impressive 400 sounds - plus 150 rhythms - to really exercise your creativity. Of the sounds, there's an excellent stereo grand piano sample - plus, all of the built-in tones have been improved using Casio's new AHL technology (Acoustic and Highly-compressed Large-waveform). Casio also increased the polyphony to 48, so you don't have to worry about sounds dropping out when you play extensive passages. There are even 10 reverb effects onboard for further shaping your sound. With the increase in polyphony, the excellent sounds and effects, and Casio's Touch Response keys, the CTK-3200 lets you play with incredible expression.Built-in lessons and play-along songs
The Casio CTK-3200 is more than a fun keyboard to play - it's also an excellent learning tool. 110 songs are in the Song Bank. The songs are divided into short, easy-to-master phrases, making it easy for just about anyone to learn to play. After you master a phrase, you'll advance to the next one until you can play the entire song. An on-screen guide shows you the notes you need to play, so the CTK-3200 can also help you learn to read music - and then directly apply that knowledge.Cool sound sampling feature
Now more fun to play than ever, the Casio CTK-3200 keyboard has a sampling function built-in. You can take anything you've recorded - up to one second long - and then connect a portable audio device to the CTK-3200's audio in jack. Load up the sound, and you can press a key and hear it! You can even add effects to give the sound more dimension. Make even more complex drum kits, or add even more expression to your playing with the CTK-3200.Casio CTK-3200 Portable Keyboard Features:
- 400 AHL keyboard voices
- 48-note polyphony
- 61 dynamic touch keys
- Step-up learning system
- 150 rhythms; Auto Accompaniment
- Sampling function
- Music Challenge
- Metronome for lesson support
- Voice pad function
- Audio input
- Pitch bend wheel
- USB plug-and-play
- Headphone connection
- Onboard stereo speaker system
- Runs on 6 AA batteries or included AC adaptor


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Tom Thumb Meets Thumbelina Trailer (1996)
"Enchanted Tales" 17 September 1996 Animated, Family 54 mins
She slept in a flower; he rode a snail. Together, they make up fabulous adventures in the Enchanted Tale: Tom Thumb meets Thumbelina. In their small world, the two encounter fairies and princes in surprise after surprise. Using their wits, Thumb and Thumbelina make it through the kingdom. *** Enter a thrillingly animated kingdom of mischievous fairies, wicked princes, and a pair of very little people caught up in a very big andventure. Join Thumbelina and Tom Thumbas save the Great Meadow!
Watch the official Tom Thumb Meets Thumbelina 1996 trailer in HD below or find more Tom Thumb Meets Thumbelina videos on Vidimovie.com.
Watch Tom Thumb Meets Thumbelina Free on Popcorn Time Online


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hi everyone.. my problem is that i just changed my system from domain to workgroup an applied the settings of domain which i collected before change to worgroup. now when i try to access my computer from other computer in lan pop up menu is showing that guest account in grayed textbox and prompting for password, but my computer has the administrator privilege. But my computer can access other computers connected to the lan. please help.
If you removed the computer from the Domain, then you'll need to create local users that the other Domain users will then use to access the shares.
Domain authentication won't work..
thanks for the reply..i have got the solution for the problem from this site from another post...
here is that solution
Check XP Security policies in gpedit.msc:
Found in Security Settings\Local Policies\User Rights Assignment
- Access this computer from the network: add guest
- Deny logon locally: remove guest
- Deny access to this computer from the network-> check Guest is not here.
- Network access:Sharing and security model... -> Guest only
Found in Security Settings\Local Policies\Security Options
Security-wise, that's a bad idea.
A very bad idea, indeed.
A man can be happy with any woman as long as he does not love her.
> - Oscar Wilde


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- Hi there, welcome to Tribesmart. Log in to get started...
Rhinestone Decoration Collar Long Sleeve Blouse
Guide price: $40
Last updated on 7th Jun 2012
Rhinestone Decoration Collar Long Sleeve Blouse
Color: Various colors available
Material: 95% Terylene & 5% Spandex
Brand: Other Brand
Made in Asia
Fashionable and delicate sleeve design of the women shirt can show your high taste
High quality Designer Women Blouse is comfortable for you to wear
Wearing this cool Designer Women Blouse would never be out of fashion
This blouse is simple and concise in design to make you decent for kinds of occasions
The fashionable design of the Designer Women Blouse is very fashionable
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Free size fits most people
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What's it like to be black in a white city?
Americans are often uncomfortable with the unfamiliar. Traveling outside the United States for many, creates insecurities because of language, customs and sometimes because of the first time experience of being a minority. But those differences surround us every day in our own country.
Most of our citizens are at ease with the combination of the American culture mixed with their ethnic origins. But Phoenix is a uniquely Caucasian community. As settlers moved west, people of color were often left behind in the east and the cities of the middle west. That separation geographically and racially now offers the opportunity to answer the question, "What's it like being black in a white city?"
Sponsored Articles
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Ring Gear Stabilizer Kit
Part No.
- Ring Gear Stabilizer Race
- Bearing Buttons (5)
For 1.82 ratio stamped steel carriers only.
Vibrations at high speeds and broken Reverse friction plates are common problems with GM Powerglide racing transmissions. These issues occur when the poorly supported planetary ring gear moves off the transmission center line, oscillating out of control. Sonnax ring gear stabilizer kit 28510-S1 welds to formed steel, 1.82 ratio planetary carriers to support the ring gear, keeping it on-center.
The following tools are required to install this ring gear stablizer kit:
- Three 4" C-clamps
- 1/8" Drill bit
- 1/4" Drill bit
- Welder, MIG or TIG
- Patent Pending
Related Parts
Click here to view PDF if instructions do not appear below.


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Camping in the lake ecosystem at Red Hills near Ooty in Tamil Nadu, India
It was time for another weekend camping trip. 7 of us left Bangalore one early Saturday morning equipped with all our camping gear towards Red Hills in Tamil Nadu.
The Red Hills area, 28 km from Ooty is an ecologically fragile zone of the Nilgiri Biosphere Reserve. It is situated approximately 325 kms south of Bangalore.
The group, which left home from different parts of the city, met up at the Raja Rajeshwari arch on the Bangalore-Mysore highway. After coasting on the highway for an hour and after beating the morning traffic, we stopped at Maddur Tiffany's at breakfast. This was followed by a brief stopover at Mysore to shop for some groceries and brew.
Soon, the scenic 36 hairpin bends that led to Ooty lay before us. It was great fun ascending through the winding roads. The nip in the air increased as we reached Ooty.
Upon reaching Ooty, we stopped by a restaurant for lunch, got proper directions and headed towards the narrow Muthorai road that leads out of Ooty to the villages of Palada, Ithalar and Emerald, all surrounded by acres of cabbage and carrot and further towards Red Hills.
At Red Hills, the forests are magnificent and vast, the foliage is dense and the air, crisp and pure. Lush eye-soothing greenery covered the whole area right into the horizon. Ringed by an almost never-ending array of mountains, clothed in green finery, Red Hills, so named by the British, in remembrance of a similar area in England, is where tranquillity meets calm to produce a sense that is soothing and soul-enriching.
Our initial plan was to camp by one of the 8 lakes that cover this region, but due to some unforeseen circumstances (local trouble), we had to change our plans and instead camp at the Red Hills Nature Resort that overlooks the Emerald lake.
Situated on a hillock at 7,000 feet, the Red Hills Nature resort, is a bungalow that dates back to 1875. It has a sprawling 250 acre tea garden that encircles the surroundings.
Shortly, we set up camp, had some tea and snacks and went on a short hike to a nearby hillock that offered breathtaking views of the valleys and the countryside. As evening set in, we got ourselves a roaring camp fire, sipped into our drinks and had a sumptuous dinner as the temperature started dipping. By midnight, all of us decided to turn in.
It was an early morning call for us and after performing our morning duties, we took a walk down the tea garden and towards the lake. After spending some time in the water, we made our way back to our camp for some much needed breakfast.
After sunbathing for a while on the green lawns, we packed up our camp and made our way back to Ooty. Enroute, we stopped and chilled out on the banks of another lake.
Once we reached Ooty, we had lunch, bought some home-made chocolates for the folks in Bangalore and proceeded to make our descent. We finally reached Bangalore by dinner time.
A great camping trip and Red Hills, a lesser known hill station, is a fantastic weekend getaway from Bangalore!!


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http://saltlakecomiccon.com/wp-content/uploads/2013/08/Jess-smart-Smiley.jpg 919 656 Salt Lake Comic Con http://saltlakecomiccon.com/wp-content/uploads/2017/01/FanX17-header-logo-2.png Salt Lake Comic Con2013-08-12 19:10:422013-08-23 16:13:00Jess Smart Smiley to Join Salt Lake Comic Con
Salt Lake Comic Con is excited to have Jess Smart Smiley as a guest September 5-7th. Jess is the author/illustrator of Upside Down: A Vampire Tale, and the creator of Rumpus on the Run: A Monster Look-n-Find Book.
Join the conversation on Facebook.


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Topix Mobile
Read the Khalif Wyatt news page on your web-enabled phone or wireless PDA
Now you can get Khalif Wyatt news on your phone!
Enter your phone number and we'll send you a link to the Khalif Wyatt page that you can view in your mobile browser.
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Wordpress Becomes Default Blogging Platform in Windows Live
Move replaces Windows Live Spaces, adds 7 million users to WordPress.
Windows Live and WordPress.com are partnering to make WordPress the default blogging platform in Windows Live. Today at TechCrunch Disrupt Dharmesh Mehta, director of Windows Live product management made the announcement, which moves away from Windows Live Spaces, the current blogging platform.
The move to WordPress instantly gives the open source blogging CMS an additional 7 million users. Existing Windows Live Spaces users get 6 months to migrate their blogs to WordPress before they go bye-bye.
WordPress powers roughly 9 percent of all sites on the Web today and accounts for about 26 million active blogs.
Issue 28: GIMP Handbook 4th Ed./Special Editions
Buy this issue as a PDF
OpenSUSE Site Hacked
News site for the openSUSE community falls victim to a Wordpress exploit.
LibreOffice Goes Online with 5.3 Release
The source code is available online.
Microsoft Brings Clear Linux OS to Azure
One out of three virtual machines on Microsoft Azure Cloud run Linux.
ASUS Announces a Single-Board Computer
The form factor of the board makes it a drop-in replacement for Raspberry Pi.
Red Hat Releases RHEL 6.9 Beta
Makes it easier for customers to move workloads into container-centric applications.
SUSE Working on a New Operating System Called MicroOS
SUSE's answer to container-centric operating systems.
Biggest Kernel Release Ever
Linux 4.9 is the biggest release in terms of number of commits.
CentOS Linux 7 (1611) Released
The latest version of the official RHEL clone is here.
openSUSE Rolls Out 42.2 Leap
New release targets Linux professionals.
Cutting-Edge Fedora 25 Released
The Fedora project adds Wayland and Gnome 3.22


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Ever delayed your trip to Sainsbury's to watch the 4.10 at Doncaster? Do you get frustrated when you have to leave your sitting room right before a big race?
Well fret no more! You can now watch Live Horse Racing on the go when you bet with StanJames.com. Simply place a minimum of a £1 bet to catch the race from wherever you are, on your Mobile or Tablet.
Follow these 5 simple steps to be a part of the action today:
- Log into your StanJames account on Mobile or Tablet
- Place a minimum bet of £1 on any UK Horse Race
- Qualifying race is listed in "My Live Races"
- Click watch in "My Live Races" to start the live stream or navigate to "My Live Races" from the "Horse Racing Tab"
- Sit back and enjoy the action
So whether you're going for the favourite at Lingfield, or backing an outsider at Ascot, you'll now be able to enjoy the thrills of a day's racing at your fingertips no matter where you may be!
Click here for today's Horse Racing Betting
Terms and conditions
To watch the horse you have backed live at StanJames.com
- Place a bet of a minimum of £1 win single on a race covered by At The Races or Racing UK.
- Multiples should be £1 per selection (e.g. Double £2 would be required to watch both races, treble of £3 for three etc.)
- Please note: streams will only be accessible for as long as your multiple bet is still Open/Unsettled.
- Only races from UK & Ireland will qualifiy for Live Streaming
- Only customers based in Uk & Ireland can watch live streaming


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'Finding Dory' Beats 'Tarzan' for Third Straight Box Office Winby and
Pixar's sequel to 'Nemo' also tops Spielberg's 'The BFG'
Total box office marks the fourth-biggest July 4 weekend
"Finding Dory," the Pixar film in its third week of release, outdrew three new movies over the U.S. Independence Day weekend, including a Steven Spielberg picture and a costly "Tarzan" feature.
"Dory," a sequel from Walt Disney Co., collected $50.2 million in North American theaters from Friday to Monday over the long weekend, ComScore Inc. estimated Monday in an e-mailed statement. Warner Bros.' "The Legend of Tarzan" landed in second place with $45.6 million, Universal Pictures' "The Purge: Election Year" was third with $34.8 million and Spielberg's children's movie "The BFG" placed fourth with $22.3 million.
The total box-office sales of about $225 million from Friday through Monday would be the fourth biggest July 4th weekend ever, comScore said.
The haul made Disney and Warner Bros. the weekend's big winners. Still, Universal's "The Purge," a dystopian thriller, cost just $10 million to make, according to Box Office Mojo, suggesting a profitable theatrical run. "Dory" headed into the weekend with $330 million in domestic revenue, making it one of the top 2016 films. Analysts at BoxOfficePro.com were expecting weekend sales through Monday to rise from a year ago.
"Dory" was forecast to collect $52.3 million over four days, according to analysts at Box Office Mojo. The picture is a sequel to the highly successful 2003 film "Finding Nemo."
"The Purge: Election Year" exceeded forecasts after Box Office Mojo predicted it would take in $30.9 million through Monday for Comcast Corp.'s film division. It's the third picture in a series about a society where crimes are legal for a night. Critics were split, with 55 percent giving positive reviews at RottenTomatoes.com.
The box-office tally for "The Legend of Tarzan" was a better-than-expected debut for Warner Bros. The film, which cost $180 million to make and tens of millions more to market, was projected by Doug Stone at Box Office Analyst to make as much as $29 million through Monday, a sum the studio will split with theaters.
Burbank, California-based Disney also released Spielberg's "The BFG," which is based on the book by Roald Dahl and features Oscar winner Mark Rylance as the benevolent giant who befriends a young girl.
The movie scored well with critics, garnering 72 percent positive reviews. Analyst Stone was forecasting as much as $19 million for four days, while the studio was expecting around $30 million. The film cost $140 million to make.


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According to a new research study from Wharton and the Verde Group – published in the Results of The Retail Customer Dissatisfaction Study 2006 (PDF) – of those shoppers who experienced problems with a retailer, only 6% contacted the company, but 31% went on to tell friends and family. Of those, 8% told one person, 8% told two people, and 6% told six or more people. The study further found that out of 100 dissatisfied customers a retailer stands to lose between 32 and 36 current or potential customers.
While this is less than the old rule of thumb which said that you typically only hear from 1 out of 10 dissatisfied customers – the impact of negative word of mouth can be more devastating as the tools that amplify word of mouth are getting increasingly powerful.
The study truly illustrates the power of negative word of mouth and the retelling of stories. Indeed, and according to the study, "the complaints have an even greater impact on shoppers who were not directly involved as the story spreads and is embellished. Almost half those surveyed, 48%, reported they have avoided a store in the past because of someone else's negative experience."
[Technorati Tags: word of mouth marketing WOM viral marketing retail marketing]


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Elena S. Omelchenko
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Uploaded on November 11, 2011
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Is The Old Boys School incorrect or missing key business information? Update your Hotfrog listing today.
Contact details
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Hotfrog Ireland provides information regarding The Old Boys School in Garristown Dublin. The Old Boys School is located at Main St, Garristown Dublin and provides Education services.
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View other listings in Reservoir, Carlton, Heidelberg West, Bundoora, Ivanhoe, Heidelberg Heights.
Online 4 months ago
Rent budget
Preferred stay length
Move date
I've been travelling and working around Australia and Europe
Looking for a room for about 10 weeks near Heidelberg Heights from the 31st of October. I'm a clean and quiet housemate but also sociable and fun!
Adam is also interested in Teaming-Up and starting a new share house.


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Hopefully my July AIS bulletin is waiting for me in the mailbox!
El, near Winnipeg
Manitoba, Canada Z3
-----Original Message-----
From: email@example.com <email@example.com>
To: firstname.lastname@example.com <firstname.lastname@example.com>
Date: Saturday, August 04, 2001 11:30 AM
Subject: Re: [iris-talk] AIS:2002 Symposium
>We have not understood what to do either.
>Okay so the affiliates can vote too, did each affiliate get sent a ballot?
>Were they sent to the RVP or the President of the affiliate? It would seem
>me the President would just duplicate her or his ballot.
------------------------ Yahoo! Groups Sponsor ---------------------~-->
Small business owners...
Tell us what you think!
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The Vanilla Pod Bakery
local, wedding cakes, handmade
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Fabulous bespoke brithday cakes from the Vanilla Pod Bakery.
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text: A Few WWDC Takeaways That Didn't Fit Anywhere ElseBrian Barrett6/03/14 3:05pmFiled to: applewwdcwwdc2014iososxchatroom615EditPromoteShare to KinjaToggle Conversation toolsGo to permalink There's a lot to unpack from Apple's WWDC keynote yesterday, and we've been doing plenty of that already. But instead of trying to force a few thousand more words on you about what it all means, it seems more humane to just talk out a few of the bits and pieces that have stuck with us so far. So here, in no particular order, are a few thoughts on WWDC and what it all might add up to. Please do add your own in the discussion below! There's a lot to talk about. Advertisement Advertisement TouchID's going to make a great wallet replacement someday. Not today, and not even any time particularly soon. But by opening up TouchID to developers, Apple took an important first step towards turning your iPhone into a wallet replacement. The tech we need to pay with our phones exists today; the problem is that it's still way more annoying than just swiping a card. Being a thumb-press away from a Passbook-stored credit card would be more efficient (at least than all the steps we have to go through now) and more secure. Splitscreen iPad multitasking are almost definitely coming, and are going to be great. This was Hot Rumor that got quashed but good by Brian X Chen at the NYT. But Apple's iOS Extensibility feature—which lets apps communicate with one another—did make an appearance yesterday. It's exciting for a lot of reasons, but also very specifically for this one. Sponsored Thanks to Extensibility, it's easy to imagine that when the iPad does embrace splitscreen multitasking, it'll do it in a way that lets your apps interact while both are open. See something you like in Safari, open up Pinterest in a split screen, drag and drop onto your board.An iPhone will be a terrible smart home remote. There's a lot to be said about smart homes that probably shouldn't be said until it's clear that anyone actually wants one. But I can't help but be struck by how annoying it would be to have an iPhone—or any current smartphone—control your home. Advertisement Think of how frustrating it is when your TV remote dies. Now imagine if your TV remote ran out of juice every afternoon, and also controlled your garage door and alarm system, and HVAC unit. It's not the end of the world—homes have outlets, outlets have electricity, it's fine—but we have enough to worry about when our phones die already without wondering if we'll be able to open the garage door. [Clarification: Yes, of course there will be other ways to control these things. But if you come to rely on your iPhone and it suddenly doesn't work any more, that will be a little bit annoying, and little annoyances tend to add up. That is all.] The more open Apple gets, the harder it'll be to leave. There's been a lot of focus on how Apple's opening up more, especially with HealthKit and HomeKit. And while that's mostly true, if you think it's hard to leave iOS now just think how hard it'll be when your refrigerator, security system, and, I don't know, respirator run on it. Apple's opening up to more hardware partners, but also making your exit strategy way, way more expensive. Advertisement Being able to use whatever keyboard you want is pretty great, though. What's going on with Apple TV? I mean, right? If Apple doesn't want to open it up to developers, that's fine, but its main living room product—a space that it cares about very much!—is starting to feel pretty stale next to the competition. The hope, I guess, is that it's holding off until some kind of hardware refresh this fall to unlock Apple TV's full app, gaming, cable box (maybe?) potential. Then again, I could've said the exact same thing the last three WWDCs. Advertisement What a tough world to be a dev. Well, not most devs. Most devs are fine (I assume?). But Apple and Google haven't been shy the last few years about replicating the best apps for their platforms in-house, and squeezing out the people who dreamed them up. And honestly, they should! It's just good business sense. But it's a wonder everyone doesn't just sell out before they get pushed out.Anything else? This is just what's been bouncing around in my brain since yesterday afternoon; there's plenty more speculating and deducing to be done, especially since the payoff for most of what we saw yesterday won't actually exist until two or three (or more) years from now. Let's talk it out below.Reply61 repliesLeave a reply


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Nature or nurture? It's the perennial teaser that sociologists and psychologists, parents, politicians and even the police have posed when trying to understand the behaviour, or sadly more usually the misbehaviour, of young people.
And it's a question I can't help but ponder myself – almost on a daily basis – as I observe the constantly evolving character traits of my young son.
Krishan is now almost three and a half years old, and over the past few months I've observed a radical change in the way that he treats both me and my partner.
From when he was born up until a few months ago, Krishan would always run to his mum for solace. If ever he stubbed one of his tiny toes, tripped over a toy or just got frustrated with something through lack of sleep, he'd always seek salvation in her arms. If ever I even attempted to comfort him, he'd turn away, sometimes even lashing out in the process.
The parameters were quite clearly defined – whenever anything went wrong, whenever he was tired, in fact any time that he felt out of his toddler comfort zone he'd go to her.
But now things have changed – specifically, his attitude towards me. Where before he'd actively seek my partner out, now he seems just as happy (on the majority of occasions) to be consoled by me. Obviously, mum still tops the "cuddles pecking order", but at least dad now registers on the scale.
What warms my heart the most is the way that he waits for me to come home. Nowadays, he genuinely seems delighted to see his dad, and he's clearly aware that there are some things he can do with me that he can't with my partner.
He knows that with me he can wrestle and play fight. But my partner is certainly not in the least bit happy to have our three-year-old attempt to punch her on the nose (however playfully).
This "male-ness" has certainly started to rise to the top in recent months. Where before he would happily run around playing with anything, now his toys and games have taken on a more masculine flavour.
When he was much younger, Krishan used to enjoy pushing around a baby's pushchair. At first, my male ego was appalled – that my son was playing with what usually is a girl's toy. But no sooner had I conjured these thoughts than I was ashamed to have them. There I was, conforming to the sort of gender bias that as a balanced parent I was seeking to avoid. And, more to the point, didn't I spend half my time pushing him around in a pushchair anyway? Surely a pushchair is not an innately feminine article?
Now, on most days, our flat looks like a miniature car-wrecking yard. There are toy cars of all shapes and sizes littering the floor. Visitors have to be careful where they tread – you could risk life, limb or (perhaps, worse) a toddler's wrath if his prized HotWheels suffers a busted axle from your misplaced foot.
So where does he get this love of four-wheeled vehicles from? Admittedly, some of his first cars came from an uncle who'd safely squirrelled away his own prized childhood collection in his parents' attic.
But it's not just toys – he loves fire engines, police cars, dumper trucks, even the dustbin lorry. And if we're on the motorway and pass some roadworks with their assorted maintenance vehicles, the squeals of joy from his car seat can be deafening.
In fact, it almost – almost – makes up for the disruption in the journey. It certainly makes those maddening cone-counting moments pass more easily.
So is this nature coming to the fore? Is there some deep-seated petrol/large vehicle love affair lying dormant inside all little boy genes?
Perhaps we just have to accept that boys and girls are as polar opposite as the "sugar and spice" and "puppy-dog tales" from those old nursery rhymes. And any attempt to try to change this internal chemistry is futile.
- More about:
- Cars
- Police
- Sleep
- Waste Disposal


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Top Definition
A bra worn by a women that stuffs money or other items that are usualy kept in a walet.
Thanx for sucking me off, heres 5 bucks, you better put it in your bralet.
by zeke paine the founder of the bralet July 11, 2006
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Smooth, soft, slim fit American Apparel shirt. Custom printed. 100% fine jersey cotton, except for heather grey (90% cotton).Buy the t-shirt


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Log in to create groups for projects or interests and save some images to them. More about groups.
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southLAnd – Top Chef Master Suzanne Tracht makes simple simply amazing. I mean the humble roast beef is elevated to star status. Bring a cig. You may want to smoke it after you "finish."
Saved from


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[2ChicksSameTime.com/NaughtyAmerica.com] Monique Alexander, Tasha Reign - 16457 (2013) [HD 720p]
Here you will find fresh porn videos, movies for every taste. You can download their by clicking on the link site file-sharing service Nitroflare, Uploaded, Gigapeta, Keep2Share.cc and many other.
Number on a site: 16457
Release date: July 4, 2013
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Happy Fourth of July!!! To celebrate, Monique Alexander and Tasha Reign are frolicking in the pool, topless with their tits hanging out, while Danny is cooking hotdogs on the grill. But while those weiners are roasting, the girls want to roast Danny's footlong in their hot mouths and pussies! Three isn't a crowd on Independence Day as this backyard threesome heats up with some good ol' fashion fucking! No need for fireworks ... all the banging you need is right here!!!
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Search Prestwick Airport Parking
Search parking at
Glasgow Prestwick
Available from £4.75 per day or £38.00 per week.
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Our Kent-based support team are friendly, knowledgable and ready to help with a new or existing booking.
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The best choice of Prestwick airport parking from only £6.63 per day or £53.00 per week.
Why pay the expensive gate rate prices for Glasgow Prestwick airport parking? If you turn up at without pre-booking your Prestwick airport short and long stay parking, you have to hunt down a spare parking space and also pay the expensive gate price. The gate rate can be as much as £13 per day. Pre-booking with Holiday Extras® ensures you make a saving on the gate rate and helps avoid the hassle of trying to find a parking space. We check over 100 prices a week in order to bring you some great deals on your airport parking, saving you as much as 60%.
Prestwick airport parking customers' rating: 90% (8,255 reviews).
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Map & DirectionsPhotosReviews
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Aviation House
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*This is an example price for reservations between 23-04-2017 and 30-04-2017, valid as of 21-02-2017.
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The long stay car park was closed at Prestwick when we arrived. There was a sign on the door advising us of this. We were diverted to the other car park at Prestwick. Everything was ok though.Mrs O'neill, 12 Dec, 2015 (5 out of 5)
Airport parking at Prestwick. only small hitch was we were upgraded to the closer car park but when we went to leave the barrier wouldn't rise as apparently we were outstanding almost £300 this was solved very quickly by the attendant who let us out.Mr Orr, 13 Dec, 2015 (5 out of 5)
Very easy parking for Prestwick Airport. We will definitely use again.Mrs Johnstone, 17 Dec, 2015 (5 out of 5)
Very happy with aspects of your service,will use Prestwick airport againMr Weir, 20 Dec, 2015 (5 out of 5)
Very smooth operation no hassle even when flight delayed we had no problem leaving the car park at prestwick. Pleasant and helpful staff.Mr Kerr, 22 Oct, 2016 (5 out of 5)
Our Glasgow Prestwick airport parking is rated 90% by 8255 guests
Holiday Extras offers a range of cheap Prestwick airport parking: Prestwick on-airport parking, Prestwick off-airport parking and Prestwick airport park and ride. The choice of car parks at Prestwick coupled with great low prices make Holiday Extras the best place to book your Prestwick parking. It's easy to book online or over the phone. Browse our full list of parking options at Prestwick to find the option that suits you.
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Prestwick on-airport parking
The Prestwick Short Stay car park is situated within the airport perimeter, which means the airport terminal is just a short walk from the car park. The closer, on-airport options cost a little more than the off-airport parking option. The on-airport car park is shown in the product table below with a small plane in the features column. The on-airport parking service at Prestwick airport is well sign-posted and easily accessible.
Take a look at our Prestwick airport parking transfers and Prestwick airport disabled parking if you need any more information.
To see what else we can include in your parking booking, take a look at our Prestwick airport parking upgrades.
For all our reviews and customer scores visit our Prestwick airport parking reviews page.


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January 7: What Are We Wearing Today?
Hey! So sorry about the tech issues on Friday that left the site either not working at all or just not updating with new content. There was some sort of "broken node," according to our tech team, but all seems to be resolved. Here's to a new week! And a new set of outfits! Click on to see what we're wearing today…
5 Signs You Belong Together
We've all heard the old saying that there's someone out there for everyone. Here are a few signs you can look for to figure out just how well you and your partner mesh together.
3 Reasons to Stay Single
There are plenty of benefits to being in a relationship, but there are just as many reasons for staying single.
9 Sexual Communication Tips
Talking about sex can be stressful, Here are nine helpful tips to make it easier.
Top 5 Gifts for Couples
Are you looking for something you can share with your partner? Check out these great recommendations to find something that you'll both love.
Top 5 Gifts for Him
Not sure what to get your man? Check out some of the top gift ideas from the guys at Adam & Eve.
Indulge in a little "me time"
Adam & Eve Adult Toys. Always Discreet, Free Shipping and Bonus Gifts.


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Share house
Share house
5 Bedrooms
5 Beds
2 Bathrooms
2 Baths
5 Flatmates
5 Flatmates
|Room Type
|Private room
|Shared bathroom
|Length of Stay
|Maximum 3 months
|Anyone welcome
|Weekly rent
|2 weeks rent
|Not included in rent
|Unlimited included in rent
|On street parking
Hello :) We have a room available temporarily in a large North Melbourne house.
It's a 5bed/2bath house with heaps of room (big lounge, open plan dining/kitchen area and backyard). Good set of speakers in the common areas to keep things lively. The whole house has wooden flooring.
Air-conditioning/heating units are in the room but we tend to keep them off unless things are dire...
We live right outside the 57 tram line, 20 mins to get to the CBD, and a 15 min walk to Errol St, Queen Vic Markets or Kensington!
Looking for someone friendly between 20-26 who knows how to keep a house clean
The room has a BIR, fireplace, a nice window with natural light, aircon/heating unit and a chandelier.
The room is available for any amount of time up to 3 months with preference going to those who are around for longer.
Also the furniture since the photos has changed! Room comes with a large queen bed
We are five flatmates who are also great friends :)
Ranging in ages from 21-26 and hailing from Perth, NSW, ACT, New Zealand and France! We are a very short walk to uni although only three of us are studying with the rest working part/full time.
More share house listings in North Melbourne, Melbourne


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One of the long-standing issues with 360-degree sphere videos is that hands are tripods are usually visible in the shot. The throwable Panono camera does solve this issue, but its recording time is limited to how long it can stay in the air once thrown.
Enter Varavon, a South Korean film equipment manufacturer, with the VR Gimbal, a three-axis, six-propeller gimbal drone that can film a full 360-degree video without being visible in the image. The drone's powerful stabilizer allows it to move freely without disturbing its fragile footage-capture process.
While Varavon hasn't yet set an official price for the VR Gimble, they predict that their drone will cost $30,000. This is a bold move, TechCrunch's Haje Jan Kamps says, given that a competitor exists for one-fifth of this price.


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Called the "original Modern Family," this comedy play follows the freethinking Sycamore family and mayhem that ensues when their daughter's fiancé brings his conservative, straight-laced parents to dinner on the wrong night. (August 26, 2014-January 4, 2015). Some discount tickets are still available, so make sure to catch the amazing James Earl Jones and co-star Rose Byrne this season on Broadway!
Home You Can't Take It With You Broadway Comedy Starring James Earl Jones
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More Time To Travel accrues two more accolades…
In a world filled with inspiring "travel content," it's always exciting when your work is noticed and acknowledged by colleagues.
Guest blogger Susan Campbell gives us the scoop on what's new in Aruba.
The poignant themes of the Off-Broadway production "Not That Jewish" will resonate with a wide audience of theatergoers.
Looking back at our travels in 2016 and hoping for 'more time to travel' in 2017!
Holland America Line and O, The Oprah Magazine just announced a partnership to promote the transformative power of travel.
River cruises are a great choice for traveling solo.
Guest contributors John and Sandra Nowlan offer readers a sneak peek aboard the new Holland America Line Koningsdam where food takes center stage.
The term farm-to-table has become so popular that it's often overused—and misused.
Each time we return to Gotham Bar and Grill, we're captivated by the consistent perfection of the culinary experience.
Contributing writers John and Sandra Nowlan experience the tastes of Texas on a food trail expanding from Forth Worth to Dallas.
Guest bloggers John and Sandra Nowlan visit the Mexican Riviera and sample the good life at two relaxing resorts, Zoetry Paraiso de la Bonita and Secrets Capri Riviera Cancun. Maybe it's our age, but our ideal all-inclusive Mexican get-away now involves a relatively small resort, a natural and eco-friendly tropical setting, wonderful food, a great beach
A wedding at the Marriott Essex House gave us an opportunity to check out this classic hotel…
Guest contributor Laura Kelly writes about her visit to the Ojai Valley Inn & Spa, a dreamy destination along many dimensions.
Guest contributor Laura Kelly shares how hygge, the Danish lifestyle trend, is warming up everywhere.
Experts offer advice on how travelers over 50 can avoid or minimize the risk of falls when traveling.
The cabin steward plays a key role in the life of any cruiser. Here are five attributes of a good cabin steward.
Getting Naked for Money is a witty memoir by my erudite, but down-to-earth travel writer friend and colleague, Edie Jarolim.
Here are some of our favorites gifts for the over-50 traveler that are available on Amazon.
An interview with travel author and entrepreneur Andy Steves, and an opportunity to win a copy of his new book.
In a world filled with inspiring "travel content," it's always exciting when your work is noticed and acknowledged by colleagues.
Homeaway is offering one lucky winner the opportunity to stay in a 14th century castle in Duns, Scotland.
Win the chance to spend a weekend for two in Verona, Italy.
Feeling dowdy? Need a Big Apple makeover?


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QB-Matt Moore
RB-Mike Goodson
WR-Devery Henderson
TE-Ben Watson
OL-Phil Loadholt
OL-Garret Reynolds
DL-Sammie Lee Hill
LB-Manny Lawson
DB-Tracy Porter
QB-Matt Moore
RB-Mike Goodson
WR-Devery Henderson
TE-Ben Watson
OL-Phil Loadholt
OL-Garret Reynolds
DL-Sammie Lee Hill
LB-Manny Lawson
DB-Tracy Porter
1) Takarist Mckinnley-OLB-UCLA
2) Pat Mahommes_QB-TT
3) Rasul Douglass-CB-WVU
4) Samaje Perine-RB-OU
5) Bryan Cox-Edge-Florida
5c) Jalen-Reeves-Maybin-ILB-Tennessee
6) Akhello Weatherspoon-CB-Colorado
7) Billy Butler-TE-Shepherd
I saw Brandon Jacobs was released by the 49ers. With our RB situation, is he worth taking a look at?
The Rams' offense featuring weapons such as Marshall Faulk, Torrey Holt, and Isaac Bruce were known as "The Greatest Show on Turf"
The Steelers' offense featuring weapons such as Le'Veon Bell and Martavis Bryant should be known as "The Greatest Show on Grass"
This has nothing at all to do with respective playing surfaces at the Edward Jones Dome vs. Heinz Field.
2015 MNF Executive Champion!
I know he's been fairly vocal about his unhappiness in SF. I don't expect many on the board to be keen on the idea of giving him a look. I was big on him coming out of college, and at this point and looking at all possible RB options to try and fix our RB situation.
Tracy Porter. Absolutely. Getting him after an injury filled year could be a great value. If he can come cheap enough that will give great flexibility in figuring out what to do with Lewis and Taylor.
Plus his high risk/high reward play seems at odds with LeBeaus philosophy imo.
1. C.J. Mosley LB Alabama
2. Jordan Matthews WR Vanderbilt
3. (comp) Philip Gaines CB Rice
4. Arthur Lynch TE Georgia
5. Ross Cockrell CB Duke
5. (comp) Derrick Hopkins DT Virginia Tech
6. Josh Mauro DE Stanford
6. (comp) Shaquil Barrett OLB Colorado State
7. Quincy Enunwa WR Nebraska
I would add Rey Maualuga to this list.
Steelers 2015 Draft???....Go Freak! As in....
1-Bernardrick McKinney MLB Mississippi State 6 ft 5 250 4.5 40 yard dash


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SOURCE: Commonsense & Wonder
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Victor Davis Hanson warns of the isolationist urgeHistorians in the News
Historian Victor Davis Hanson, pointing to the experience of the United States after World War I, warned of the dangers inherent in embracing isolationism during a speech at the Heritage Foundation Tuesday.
"This is the first administration that has not studied World War I or World War II or appreciates the post-war order that brought the greatest level of prosperity, personal freedom, security in the history of civilization," said Hanson. "It requires an engaged United States."Hanson detailed how World War I was the first war in American history that ended without unconditional surrender and how the murky terms under which the United States left Europe and Asia opened the door for renewed aggression that manifested itself in World War II.
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- Did Salmonella Kill Off the Aztecs?
- Jewish history is under siege in the middle east and these volunteers are risking their lives to protect it
- 'Amazon should stop selling Holocaust denial books'
- National Museum of African American History and Culture Reaches Milestone of 1 Million Visitors
- What Makes a President Great? Clipping? Sipping? Slashing?
- McMaster knows how national security policy can go wrong. Will that help him?
- Historian and Antiwar Activist Marilyn Young Dies at 79
- Trump Chooses Historian H.R. McMaster as National Security Adviser
- Holocaust Historian Deborah Lipstadt Explains Why People Believe Trump's Lies
- Princeton's Harold James warns World War Three is now a "serious threat"


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Bareck E.,Vienna University Hospital |
Ba-Ssalamah A.,Medical University of Vienna |
Brodowicz T.,Medical University of Vienna |
Eisterer W.,Innsbruck Medical University |
And 11 more authors.
Wiener Medizinische Wochenschrift | Year: 2013
Optimal treatment for patients suffering from gastrointestinal stromal tumors (GIST) is based on an interdisciplinary treatment approach. Austrian representatives of Medical and Surgical Oncology, Pathology, Radiology, Nuclear Medicine, Gastroenterology, and Laboratory Medicine issued this manuscript on a consensual base within the context of currently available and published literature. This paper contains guidelines and recommendations for diagnosis, therapy, and follow- up of GIST patients in Austria. Source
Combined Immunodeficiency Evolving into Predominant CD4+ Lymphopenia Caused by Somatic Chimerism in JAK3
Ban S.A.,Austrian Academy of Sciences |
Salzer E.,Austrian Academy of Sciences |
Eibl M.M.,Immunology Outpatient Clinic |
Linder A.,Immunology Outpatient Clinic |
And 11 more authors.
Journal of Clinical Immunology | Year: 2014
Purpose: Idiopathic CD4 lymphopenia constitutes a heterogeneous group of immunodeficiencies with characteristically low CD4+ T-cell counts with largely unknown genetic etiology. We here sought to determine the underlying molecular cause in an index family with two patients suffering from combined immunodeficiency that evolved into predominant CD4+ lymphopenia. The more severely affected index patient also presented with selective antibody deficiency against bacterial polysaccharide antigens.Methods: For the genetic analysis, we used combined homozygosity mapping and exome sequencing. Functional assays included immunoblot analysis, flow cytometry and TCR Vβ spectratyping.Results: A novel homozygous missense mutation was revealed in the kinase domain of JAK3 (c.T3196C, p.Cys1066Arg). Further analysis showed revertant chimerism in CD8+ T-cells in both patients. The additional presence of revertant CD4+ T-cells was associated with a milder clinical and immunological phenotype in the second patient, although the role somatic chimerism plays in amelioration of disease phenotype is uncertain, as presence of revertant cells had no effect on residual CD4 cell JAK3 signaling function. Residual activity of JAK3-dependent STAT3 and STAT5 signaling was also found in immortalized B-cell lines indicating a hypomorphic nature of the described mutation which likely contributes to the milder clinical phenotype.Conclusions: We here present the first case of revertant mosaicism in JAK3 deficiency, manifesting as combined immunodeficiency evolving into predominant CD4+ lymphopenia. Revertant chimerism or hypomorphic mutations in genes typically associated with more severe T-cell deficiency should be considered when assessing patients with milder forms of combined immunodeficiencies. © 2014, The Author(s). Source
Reiter M.,LabDia Labordiagnostik GmbH |
Rota P.,LabDia Labordiagnostik GmbH |
Kleber F.,LabDia Labordiagnostik GmbH |
Diem M.,LabDia Labordiagnostik GmbH |
And 2 more authors.
Pattern Recognition | Year: 2016
We propose a supervised learning approach to automatic quantification of cell populations in flow cytometric samples. One sample contains up to millions of measurement vectors with a dimensionality between 10 and 20. Normally, each measurement vector corresponds to a single cell in the biological sample. Identifying biologically meaningful cell populations is essentially a clustering problem, however, standard clustering methods are impractical, because size, shape and location of corresponding clusters may vary strongly between samples mainly due to phenotypic differences and inter-laboratory variations. In our holistic approach, we implicitly employ the structural information (such as relative locations and shape of sub-populations). A new input sample is reconstructed by a linear combination of artificial reference samples each represented by a Gaussian Mixture Model (GMM), in which for each Gaussian component the class label of the corresponding cluster of observations is known. The reference samples are calculated from a larger set of training samples by non-negative matrix factorization and can be regarded as the basis of a lower dimensional feature space, in which input samples are reconstructed. We show a method for calculating the feature space transformation based on minimization the L 2 distance defined between two GMM. The feature space representation of the sample is then used to assign each observation to one of the specified sub-populations by a Bayes decision. We present classification results on a database of about 170 patients with Acute Lymphoblastic Leukemia (ALL), where high accuracy in the prediction of relatively small leukemic populations is crucial. The approach is not limited to our application. It can be employed wherever analysis of large, multi-dimensional, numerical data of a specific class of samples with related structure has to be performed. © 2016 Elsevier Ltd. Source
Preuner S.,Childrens Cancer Research Institute |
Preuner S.,LabDia Labordiagnostik GmbH |
Danzer M.,Red Cross |
Proll J.,Red Cross |
And 6 more authors.
Journal of Molecular Diagnostics | Year: 2014
The availability of high-quality germline DNA is an important prerequisite for a variety of genetic analyses. We have shown previously that fingernail clippings provide an optimal source of autologous, constitutional DNA for PCR-based applications. However, most existing protocols for nucleic acid purification from nails do not provide sufficiently high yields of pure and intact DNA for more demanding downstream analyses such as next generation sequencing (NGS). We have extensively tested and systematically modified a number of different protocols for DNA purification from nail material to optimize the yield and quality. The integrity of DNA was determined by PCR amplification of short (<300 bp), mid-range (>400 bp), and long-range (>2 kb) sequences using different target genes. Among the methods tested, the Prepfiler Forensic DNA Extraction kit was identified as the most appropriate approach to isolation of high-quality DNA from nail clippings. A standardized input of 20 mg nail material (1 to 10 pieces of fingernail clippings) yielded a mean of 1 μg DNA (range, 0.5 to 2.3 μg). Subsequent PCR-analysis revealed efficient amplifiability of short and mid-range targets in 93% and 90%, and long-range fragments in 60% of the samples tested. The adequacy for next generation sequencing applications was demonstrated by successful high-resolution HLA-typing in ten transplant recipients. Hence, the protocol presented facilitates the exploitation of fingernail material even for demanding genomic analyses both in research and diagnostics. © 2014 American Society for Investigative Pathology and the Association for Molecular Pathology. Published by Elsevier Inc. All rights reserved. Source
Rapid identification of compound mutations in patients with Philadelphia-positive leukaemias by long-range next generation sequencing
Kastner R.,Childrens Cancer Research Institute |
Kastner R.,LabDia Labordiagnostik GmbH |
Zopf A.,Red Cross |
Preuner S.,Childrens Cancer Research Institute |
And 9 more authors.
European Journal of Cancer | Year: 2014
An emerging problem in patients with Philadelphia (Ph)-positive leukaemias is the occurrence of cells with multiple mutations in the BCR-ABL1 tyrosine kinase domain (TKD) associated with high resistance to different tyrosine kinase inhibitors. Rapid and sensitive detection of leukaemic subclones carrying such changes, referred to as compound mutations, is therefore of increasing clinical relevance. However, current diagnostic methods including next generation sequencing (NGS) of short fragments do not optimally meet these requirements. We have therefore established a long-range (LR) NGS approach permitting massively parallel sequencing of the entire TKD length of 933 bp in a single read using 454 sequencing with the GS FLX+ instrument (454 Life Sciences). By testing a series of individual and consecutive specimens derived from six patients with chronic myeloid leukaemia, we demonstrate that long-range NGS analysis permits sensitive identification of mutations and their assignment to the same or to separate subclones. This approach also facilitates readily interpretable documentation of insertions and deletions in the entire BCR-ABL1 TKD. The long-range NGS findings were reevaluated by an independent technical approach in select cases. Polymerase chain reaction (PCR) amplicons of the BCR-ABL1 TKD derived from individual specimens were subcloned into pGEM®-T plasmids, and >100 individual clones were subjected to analysis by Sanger sequencing. The NGS results were confirmed, thus documenting the reliability of the new technology. Long-range NGS analysis therefore provides an economic approach to the identification of compound mutations and other genetic alterations in the entire BCR-ABL1 TKD, and represents an important advancement of the diagnostic armamentarium for rapid assessment of impending resistant disease. © 2013 Elsevier Ltd. All rights reserved. Source


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- PT. Visualand Arthamediatama
- 0 reviews
- 0 gaji
Job Responsibilities:
- programs by converting project requirements into code.
Job Duties:
- Confirms project requirements and timeline by reviewing program objective, input data, and output requirements with analyst, supervisor, and client.
- Arranges project requirements in programming sequence by analyzing requirements; preparing a work flow chart and diagram using knowledge of computer capabilities, subject matter, programming language, and logic.
- Encodes project requirements by converting work flow information into computer language.
- Confirms program operation by conducting tests; modifying program sequence and/or codes.
Job Requirement:
- maximum age 30 years old.
- Candidate must possess at least a Bachelor's Degree in Computer Science/Information Technology or equivalent.
- At least 1 year of working experience in related field.
- Solid knowledge in web application programming and database. Mastering one of the following programming language and database: asp, HTML, Java Script/Query, and Microsoft SQL Server.
- Experience in making project requirement and timeline.
- Experience in performing analysis of business processes and requirements.
- Strong analytic, problem solving, and debugging skills.
Please send your application + photograph by clicking APPLY NOW
(for Member & Non Member)
Deskripsi Perusahaan
Our company (VisuaLand) was established in November 1999 under Indonesian Law by the name of PT. VisuaLand Infotelindo Mediatama. In order to focus on technology-based and integration software products, the company change its name to PT. VisuaLand Arthamediatama in 2008. Starting the business especially in customized software development. The company also provided several services related to computer technology such as computer & network installation & procurement, troubleshoot problems, hardware & software reseller/distributor, system integration and etc.
We developed partnerships relation with other local IT Providers like HP, DELL, SAP Indonesia, Oracle Indonesia, Microsoft Indonesia and others. We also developed partnerships from other countries like iWOW Connections Pte Ltd, Singapore, Lantronix Corporation, Equinox & Avocent Technology.
We have been working on various software development projects, from Windows application platform to SCO UNIX and DEC OpenVMS Platform. We have advanced experiences in developing data integration, security software, and software for handheld devices, like BarCode Scanner, PDA and Mobile Devices.
In addition, we also worked together and provide applications for government such as Election Commission Media Center, Telemarketing, and others.


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- Quick Ceiling Fan Repairs in Marlow, OK
- Dependable Marlow Ceiling Fan Repair Specialists
- Free Estimates on Ceiling Fan Repairs in Marlow
Ceiling Fan Repair in Marlow, OK
It's important to take advantage of ceiling fan repair in Marlow, OK when there is a problem that prevents your fan from operating at maximum efficiency. These fans can be incredibly beneficial for a home because of the energy savings they can help create, but you will have to keep yours in good condition over the years if you want to get the most out of them. Over time ceiling fans tend to have problems with their motors and various other parts, but you will have to get yours fixed when necessary so they will keep working perfectly.
Avg Costs for Ceiling Fan Repair
Min Cost
Max Cost
Avg Cost
$122.14 - $171.72
Find the Best Quality Ceiling Fan Repair - Marlow, OK
Quality Marlow ceiling fan repair services will ensure that your ability to keep saving money on your energy bills each month by not having to constantly run your air conditioning system in the warmer months of the year. If you have noticed that your fan has started to slow down, is making a strange noise, or doesn't work at all anymore, it is imperative that you speak with our team of professionals to fix it right away. The sooner you have your ceiling fan repair in Marlow, OK performed, the sooner you will be able to start saving money on your monthly energy bills again.
Ceiling Fan Repair Companies
Melton's Heat-Air & Appliances & Tom's Electric
Duncan, OK 73533
Holloway Technical Services LLC
107 N 2nd St
Marlow, OK 73055
Cotton Electric Co-Op
1101 W Oak Ave
Duncan, OK 73533
Marlow, OK 73055
Lights Fantastic
710 W Main St
Duncan, OK 73533
Melton's Heat-Air & Appliances & Tom's Electric
Duncan, OK 73533


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Flooring may not be the most glamorous feature of a home, but it's an element prospective buyers notice immediately—and bad flooring could be a deal breaker. No new homeowner wants to contend with severely damaged floors or seriously stained carpet. If your floors need a fast refresh, try laminate. Designed to snap easily into place, this low-cost material can be installed by homeowners of all skills, which means you'll save yourself the expense of a professional installation.
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... Fire Weather Watch in effect from Thursday morning through
Thursday evening for the South Plains... rolling plains... and
extreme southern Texas Panhandle for 20 foot winds of 20 mph or
more... relative humidities of 15 percent or less and a high fire
The National Weather Service in Lubbock has issued a Fire Weather
Watch, which is in effect from Thursday morning through Thursday
* Wind... westerly winds at 30 to 35 mph.
* Humidity... between 5 and 10 percent.
* Fuels... dry.
* Impacts... any fires that develop can spread rapidly. Outdoor
burning is discouraged.
Precautionary/preparedness actions...
A Fire Weather Watch means that critical fire weather conditions
are forecast to occur. Monitor later forecasts and possible red
flag warnings.
Severe Weather Get Mobile & Email Alerts
Castro Severe Watches & Warnings NOAA Weather Radio
Watches & Warnings
Fire Weather Watch
Issued: 3:30 AM CST Feb. 21, 2017 – National Weather Service
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text:
Klamath Falls has a population of 19,462 and is located in Klamath county.
The average in-state tuition for full time undergraduate students in cpa schools in Klamath Falls during the 2009 - 2010 school year was $3,735.00. The average tuition was $10,899.00 for non-residents studying in Oregon.
The cost, on average, for books and supplies needed for cpa schools in Klamath Falls is $1,025.00. The average cost for room and board for students living on campus at cpa schools in Klamath Falls was $8,615.00. The average cost for students living at home was $2,550.00 for the 2009 - 2010 school year. There is one cpa college in Klamath Falls for students to choose from. CPA programs in Klamath Falls reportedly graduated 3 students in the 2008 - 2009 school year.
|Average Salary
|Number Employed in City
|Accountants and Auditors
|Tax Preparers


text:
Classic tongue-in-cheekiness: 9 to 5: The Musical
Well-timed factoids and witty retorts at San Diego Music Theatre
Jon Reimer 2:30 p.m., Feb. 17
The Filipino American Arts & Culture Festival, better known as FilAmFest, celebrates their tenth-annual festival.
Share Filipino and Filipino-American culture through cultural dances, martial arts, food, games, and more.
This year's theme, "Halo-Halo: A Mix of All Good Things," is based on a favorite Filipino shaved-ice dessert called "halo-halo," translated to "mix-mix."
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text:
Three Cool Cats - Take 1 Lyrics
Song Meaning
Verse 1
Three cool cats, three cool cats
Parked on the corner in a beat-up car
Dividing up a nickel candy bar
Talking all about how sharp they are, these
Three cool cats
Verse 2
Three cool chicks, three cool chicks
Walkin' down the street swingin' their hips
Splitting up a bag of potato chips
And three cool cats did three big flips for
Three cool chicks
Verse 3
Well, the first cool cat
He said, "Man, look at that!
Man, do you see what I see?"
"I want this little chick!"
"I want that little chick!"
"Hey, man, save one chick for me!"
Verse 4
Three cool chicks, three cool chicks
They look like angels from up above
And three cool cats really fell in love
And three cool chicks made three fools of these
Three cool cats
Verse 5
Three cool cats, three cool cats, three cool cats
Threeeeeeeee cooooooool caaaaaaaaaaats
Lyrics Licensed & Provided by
Writer(s):Lyrics © Sony/ATV Music Publishing LLC
Copyright: JERRY LEIBER, MIKE STOLLER
What's Your Interpretation?
Share your thoughts on "Three Cool Cats - Take 1" by The Coasters.
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Framed - Remastered
by The Robins, Robins, The Coasters


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Jute Grocery ToteSKU #: NW-15655
Item DescriptionMore InformationAdditional Information
Great for your next run to the store. This grocery tote has long shoulder handles for easy carrying as well as added stitching to provide added strength. Large main compartment. Shoulder-length cotton handles. Price includes: 1-color imprint, 1 location
Price includes the cost of a one color imprint in one location. Please contact us at 888-206-3047 for more print options, a custom project, or additional print locations.
|Imprint Dimensions
|6"w x 6"h
|Standard Production Time


text:
Hostelworld doporučuje
Milujeme tento hostel! Dáváme mu zdvižený palec za trvale vysoké hodnocení od zákazníků a vynikající hodnocení kvality.
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- 27 úno 2017, 3 Nocí
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Hostel Uppelink Ghent
Welcome to Hostel Uppelink, a family owned hostel situated in the historical center of Ghent. Ever since our opening, the users of Hostelworld.com have voted our hostel 'Best in Belgium' (Hoscar Award... Více...
Backstay Hostel Ghent
Our hostel is conveniently located in the middle of the university nucleus of the city, opposite the renowned art centre Vooruit and just 3 minutes away from the historic city centre. The hostel offer... Více...
KaBa Hostel
KaBa Hostel offers precisely that what a budget tourist is looking for...
A cosy atmosphere in the green garden, arty lounge or wooden dinner room. Pleasant comfort in the dorms or private rooms, i... Více...
HI De Draecke Gent
In an excellent location in a quiet street right in the centre of Gent, the renewed hostel is just 150m from the famous medieval Castle of the Counts. Retaining a period facade, it offers a high stand... Více...
Treck Hostel
Our building is a former brick factory which is part of the cultural heritage of Flanders, the building is completely heated in winter so you'll be able to camp all year round.
There's a... Více...
13 O'clock Hostel
All brand new rooms of 13 O'clock Hostel are fully equipped with a private bathroom with a shower, a wash basin and a toilet. Each guest unit features a kitchenette and a desk/table, while some are al... Více...
Ecohostel Andromeda
Ship ahoy!
After sailing the seven seas we dropped our anchors in the sparkling, enchanting city of Gent. Life is pretty good in Gent, why wouldn't it be?
The city is fun and relaxed, the people... Více...
Guesthouse PoortAckere
No imposing entrance or red carpet awaits you here. No clue on the outside that behind the centuries-old frontage on Oude Houtlei is an ancient cloister: PoortAckere. We are an oasis of peace, hidden... Více...
Hotel Erasmus
The charming Erasmus Hotel is situated in a 16th century patrician house. Find yourself in the heart of the historic centre of Gent, at walking distance from all interesting places to visit.
The ro... Více...
Charme Hotel Hancelot
This authentic boutique hotel is situated in a renovated Town House dated 1840; the stylish decorated rooms are very spacious, have re-newed bathrooms and feature free wireless internet and flat-scree... Více...
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Titleist 641174812 Does not apply
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3 Dozen Masters LOGO Titleist Pro V1 Mint AAAAA Used Golf Balls #1 Ball in Golf!
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Location: Loudonville
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Condition: Used
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Gym, cycle, cardio, group fitness - it's all here!
Swimming pool & aquatic area
General purpose space available for community hire
Take a break or get an energy hit in the cafe
Workout with a group or class or on your own
Swimming pool (indoor and outdoor)
Get expert advice on exercise and fitness training
Read our tips on healthy eating
Exercise can improve your mental health
Read about membership benefits
A variety of options to suit you
Ready to get started? Find out how
Manage my membership
11 Feb 2017
Come and join Phil for a Mega Fitness Class to raise money for our 2017 Swimathon.
Read more
16 Jan 2017
Australia Day public holiday opening hours.
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3 Jan 2017
Changes to Group Fitness Timetable in January 2017
Read more
25th February 2017
Come and have some fun on the inflatable for a good cause! Read more
The Victorian YMCA.Helping Victorians for over 160yrs.
Eat smarter for a healthierhappier you!
Discover careers full of diversityworking with the YMCA.


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Captain Jefferds Inn
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- Suites
- Free High-Speed Internet
- Continental Breakfast
- Wireless internet connection in public areas
- High-speed internet in room
- Wireless internet connection in room (free)
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- Wireless internet connection in public areas
- High-speed internet in room
- Wireless internet connection in room (free)
- Breakfast Available
- Refrigerator in room
- Free High-Speed Internet
- Air-Conditioning
- Free parking
- Pets allowed
- Suites
- Continental Breakfast
TripAdvisor Reviews Captain Jefferds Inn Kennebunkport
Travel Blogs from Kennebunkport
Saying good by
... then it has gotten progressively better as we traveled south. I can't explain this but the trees were not changing in Canada except near the border. As we get further into Maine it has been more colorful. I didn't download the pictures from the camera before it went back with CW. So I missed the pictures of Kip and the few I took of Acadia. Carolyn flys out early so we say our goodbyes. It has been a few quicks weeks making our own memories. I'm lonely already. 179 ...
Cumberland Fair - Cindy Clark
... classics. The animal barns were a little crowded but clean. You can pet any of the animals at your own risk. Most of the time the animal owners are nearby and more than willing to talk to you about their animals and farm. The barns and sidewalks and reasonably handicap friendly and flat.
Don't forget the huge pumpkins and the exhibition hall! The hall had more commercial vendors than local artists this ...
Dalsza czesc roadtripa
Ostatnio nie za bardzo mialem internet zeby cos wrzucac, wiec po krotce bylismy w oceanarium w Filadelfii, mieli tam rekiny i duze hipopotamy, wynajelismy samochod zeby pojechac do six flags i Atlantic city, w six flags bylo super, nie bylo kolejek na rozne kolejki gorskie a maja ich tam duzo, teraz zmierzamy do Atlantic city, potem zostanie nam jeszcze Washington i nowy ...
Lobsters and Lighthouses in Maine
... are we all queuing for?"
"The best god darned Lobster Rolls in all of Maine!" exclaimed a George W lookalike!
And so the hour wait began with our new queue friends Bright (George.W) his wife Randy and another couple called Chet and Bonnie...how American are those names! Both couples were celebrating milestone anniversaries respectively and deemed 'Red's Easts' the best ...
Kennebunkport by Marion Cerino
... you back to the center of Kennebunkport, and a right turn will bring you around to Cape Porpoise. With so much to see in such a small area comes lots of traffic. I suggest if you plan on venturing to Kennebunkport, especially during the summer and fall, think ahead and plan for backed up traffic.
Driving down some of the back roads of Kennebunkport, various historic buildings can be seen, such as the Nott House. The Nott House, which has been ...


text:
Ocd disrorder
Iam using tablets suggested by Dr vadlamani naresh they are good but when I'm using those tablets I'm suffering from sleep and drowsiness throughout the day.iam not able to do any work due to this.tablets are divalgrence 1gm, quticad 50 mg,bionitas 4 mg daily to times.
87 Views
Doctor Answers (1) on Ocd disrorder
Dr. Phani Prasant Mulakaluri
18 yrs. of exp | Hyderabad | Psychiatrist
It is better you consult your doctor back again and get the dose of medication adjusted. Some of the side effects can be reduced by other medicines or by adjusting the dose. The medicines you are taking does not seem to be for OCD rather medicines for bpad.
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text: I have a Christian website with several sermons in RealAudio. They can be listened to with a simple RealOne Player. But I notice that they do not get many visitors in comparison to other pages of my site. Some search engines such as altavista give you the opportunity to search for audio files, so I would like to know if it is possible to put meta tags to the audio files (.rm)? I know in RealProducer there is a way to add a short description and keyword, but does that already produce the meta tags? Please let me know more, if you are knowledgeable about this. Thank you very much. The sermons are on this site: http://www.solidrockfaith.com/RealAudioSermons.html


text:
The Gender Identity Center is looking for volunteers
39.69592, -104.99703)
Cause Areas
WhenIt's flexible! We'll work with your schedule.
Where1151 S. Huron StreetDenver, CO 80223
1151 S. Huron St.
The Gender Identity Center of Colorado has branched out! We host open hours Mondays through Sundays and we need dedicated volunteers to help us make exploring gender identity shared, celebrated, and safe. So, get involved!
- Administrative Support
- Office Reception
- Community Outreach
- Market Research / Analysis
- Interactive/Social Media/SEO
- Group Facilitation
Good Match For
Requirements & Commitment
- Orientation or Training
- 4-6 hours per day at least twice a month