text:
I'm gonna start off by saying that I know that I am not the target audience for this movie. This is for the prepubescent little girls who like their "music". But, a documentary should entertain someone no matter what the topic. A good documentary would entertain anyone no matter if they like what the documentary is about or not. That being said, this movie does not do that. It is pretty much an hour and a half long commercial for One Direction; not a movie. This movie was like the first 20 minutes of the movie 'Moonwalker' but if it was the whole movie. I can't exaggerate enough on how this is the worst documentary ever. If you wanna sit through a hour and a half long infomercial then be my guest. But, if you have a functioning brain and would rather watch something that resembles a movie then I'd stay away from this.
One Direction: This Is Us
Action / Documentary / Music
One Direction: This Is Us
Action / Documentary / Music
An intimate all-access look at life on the road for the global music phenomenon. Weaved with stunning live concert footage, this inspiring feature film tells the remarkable story of Niall, Zayn, Liam, Harry and Louis' meteoric rise to fame, from their humble hometown beginnings and competing on the X-Factor, to conquering the world and performing at London's famed O2 Arena. Hear it from the boys themselves and see through their own eyes what it's really like to be One Direction.
Uploaded By: OTTO
Downloaded 91,290 times
December 06, 2013 at 12:33 PM
Tech specs3D 720p 1080p
Movie Reviews
The Worst Documentary I Have Ever Seen
A Great Movie!!
I loved this movie. I watched this movie for the first time when it came out. I thought it was going to be just another stupid biography but it was amazingly good! It isn't just a bunch of boys screwing around! There is good and happy moments and then there is the sad touchy feely moments! They are hilarious and loving boys who have made it so far in life. They are there for their families, fans, and friends and no matter how much they get caught up in their career they will never forget about the ones they love. Most people hate on them but after they see this movie they will take interest.I can't wait to see them perform live! Directioners... this one is for you!
I'm 46, a guy, a Beatles' fan, and I liked it!
I'm 46 and the father of five daughters, the three youngest being in the One-Direction target age: 12th, 8th, and 6th grade. My daughters (including a 22 and 20 year-old) have managed not to go gaga over the Back Street Boys, N-Sync, the Jonas Brothers, Justin Bieber, and the like. 1D has been a little different, in that they caught my girls' interest and have kept it. My youngest three wanted to see this, and I surprised them on Labor Day by taking them. I thought about just dropping them off, but am glad I didn't. I read a critic's review that basically said that these guys are truly nice, decent guys, and that that comes through in the movie. It does.
I'm a huge Beatles' fan, so for me, much of the movie was spent not only enjoying the music (really, it's not bad stuff) and their humble and charming personalities, but also evaluating the sociological aspects of their "Beatlemania"-type popularity.
Here's what's interesting in the comparison. Unlike the Beatles, these guys are not skilled musicians and phenomenal songwriters. Mainly, they just sing, and they're good at that. What lies under their popularity are two things that also lay under the Beatles': 1) they are very humorous and relaxed (lots of quick, on-the-fly, funny comments); and 2) they're working-class boys (lads) who are really great friends and enjoy each other. With the Beatles, I've always thought that their palpable friendship and fun humor were the factors that made them so magnetic--they enjoyed each other, were great friends, and had fun with each other on stage and off. This is even more true for One Direction, as you don't have the leadership struggle with 1D that was there between John and Paul, nor the building resentment of a George. None of One Direction is trying to become the leader, and all are avoiding being the Justin Timberlake or the Sting. They really care for each other, are great friends, and, most striking to me, are tremendously and truly humble about their success. Along with this, they verbalize many times how each member is necessary, how they'd be less successful (or may not have even made it) had one member been missing, how it was a freak of nature/act of God, so to speak, that they wound up together, and that they'd all be doing menial jobs back home right now (factory worker, fireman, working in a bakery), were it not for their fans making them big (and they're really appreciative of their fans, and treat them well). Last thing on this: there's a segment when they go back home, and we see none of them acting like a big deal with any of the folks in their home towns. That was really refreshing.
Certainly these guys aren't the musical giants the Beatles were--not even close. But just as fun, even to adults? Yes, and maybe even a little more so. This movie, the "Hard Day's Night" of One Direction, was a really fun watch.


text: Asian Guy Does Crazy Shit Click to block a category:GamingPoliticsNewsComicsAnimeOther Trollzz next random Comment Top NextComment Amazing dude performs athletic feats that most people couldn't even dream of doing. I would never want to play tag with this kid. next Tags: Asian | Kid | does | Crazy | shit | parkour | amazing +16 Views: 1627 Submitted: 01/16/2011 Facebook Twitter Google+ Tumblr Pinterest

subset: commoncrawl


text:
alright I've run into some revealfic that has given me this sudden and terrible and cruel thirst for a set-up in which Marinette tells Alya, Nino, and Adrien that she's Ladybug because [insert literally any valid excuse here; I make no pretenses about caring, none at all]. Alya flips out for all the obvious reasons and Nino's just like "jfc this explains so much" and both their minds are, like, blown and it's all a big old fuss like "MARINETTE WHAT THE HELL AND ALSO MARINETTE HOW THE HELL DID WE MISS THIS".
And meanwhile Adrien is just, like. Sitting there. Sitting there very quietly in the middle of all the chaos, with his hands folded in his lap. Marinette gives him this nervous little look, worried about how he's going to react, and Adrien puts on his Model Smile™ and beams at her, his whole face lighting up.
Because Marinette told her secret identity to Alya, and Nino, and him, who she's held maybe half a dozen semi-coherent conversations with and barely knows outside of his good son act.
But Ladybug didn't trust Chat Noir with it.


text:
The Green Shelters
yoga retreat, detox retreat, Spa Weekend
Let's give escape a shot, let's let ourselves go: discovering idyllic destinations and immersing ourselves in local traditions, settling in enchanting and secluded places, savouring fresh, juicy, quality produce, all the while receiving our therapists' close attention and taking classes to begin, or perhaps deepen, a practice. In the heart of nature, The green shelters is a confluence of benefits that yield long-term results.
The guiding principal during your stay is based on the concept of detox. This is a pause for everyone and involves no risk to the body. It's true that body cleansing means following a certain diet, but it is first and foremost a moment set aside for peace and tranquillity, so that you can reflect on yourself, listen to your body and give it a rest.
Print this page
Create your free Hotfrog business profile
Follow Hotfrog on:
Share on:
Hotfrog Small Business Hub


text:
USDCHF Weekly Analysis - June 28, 2014
Long Term Forex Analysis | by ForexCycle.com | Saturday, 28 June 2014 13:56 UTCUSDCHF failed to break above 0.9156 resistance and pulled back from 0.9036, indicating that the pair remains in downtrend from 0.9838 (May 22, 2013 high), the price action from 0.8699 could be treated as consolidation of the downtrend. Another fall to test 0.8699 support would likely be seen, a breakdown below this level will target 0.8300 area. Key resistance is at 0.9156, only break above this level could signal completion of the downtrend, then further rise to 0.9400 area could be seen.
Forex Market Analysis
Subscribe to Newsletter


text:
Silicon Valley Infomedia Pvt Ltd
AngularJS developers india, AngularJS Development india, AngularJS Development Services India,
As mobile apps have officially changed our work propensities and scanning designs, the methods for app development has additionally been through a great deal crisp changes. Of late, there are a lot of cutting-edge tools, frameworks and platforms that have eased the task of developers. Creators can now make extraordinarily helpful and top of the line mobile apps effortlessly. Subsequently, it gives a lot of client driven and supportive application to associations and in addition organizations to enhance their general business nearness through their mobile app.
Print this page
It seems Mobile applications are raining everywhere and reigning in each domain, bounteous apps are created every year to cater the needs of the customers.
Are you eager to see your iPhone app on the top of the 'Store'? Should you truly surmise that it is an agreeable undertaking? To be sure, making an iPhone application is not in the least basic and puerile, yet it will be more regrettable on the off chance that it has just 1000 downloads in one month.
Your contacts are some of the most valuable things you have on your Android device. So if you've lost one or more don't worry: we have some quick solutions to get this important data back. Here's how to recover lost contacts on Android.
If you've ever deleted a photo album by mistake or had your smartphone accidentally wipe everything from your gallery, then you know that particular variety of ''bottomless pit in your guts'' feeling. Never fear, your lost photos are not really lost at all.
Silicon Valley Infomedia developers are create MongoDB database design & Development Services. MongoDB is an opensource build web application code & prototypes with existing programming languages & server setups.
silicon valley offer Magento Web Programming India, Hire Magento Developers India, Magento Web Programmers India, Magento Web Developers India, Magento Web Development India.
silicon info providing iPhone App Development service in USA, UK, AUS, india. All types of games custom application fully customize application development service all over globe.
silicon info providing android App Development service in USA, UK, AUS, india. All types of games custom application fully customize application development service all over globe.
Silicon Valley's Web Developers has an outstanding experience in Website Development, Outsource Web Development, Web Applications. Our Website Developers are specialists in e-Commerce and database projects management.
n its earnings report for last quarter, Apple said it expects iPhone sales to slow down this year. It'll be the first time in the iPhone's history Apple has reported negative sales growth.
And because Apple is the iPhone company, you're going to see a lot of tech pundits spewing doom and gloom over the next few days now that Apple's most important, profitable product is no longer growing the way it used to.
Android 6.0 Marshmallow has at last been discharged, yet at this moment it's just accessible on a modest bunch of gadgets. It'll advance toward different leads in the coming weeks, yet as we probably am aware as a matter of fact, it may take a while to achieve everyone. No stresses: here's the way to get Android Marshmallow highlights on your telephone at this moment.
Create your free Hotfrog business profile
Follow Hotfrog on:
Share on:
Hotfrog Small Business Hub


text:
"Pistikos? exhibition" Top 5 Page for this destination Kastoria Things to Do Tip by siaki68
Kastoria Things to Do: 38 reviews and 68 photos
Mr. Pistikos is a barber and also a skilful, self-taught artist. He makes amazing miniatures of the mansions and the churches of Kastoria. His exhibition is housed in the hotel "Kastor" and it is open to the public
Address: Hotel "Kastor"
More Things to Do in Kastoria (7)
1 - 0 of 0
siaki68's Related Pages
"always keep an open mind.."
- Member Rank:
- 0 1 5 7 7
- 112 Reviews
- 131 Photos
- Add Friend
- Follow
- Send Message
Have you been to Kastoria?Share Your Travels


text:
This profile was last updated on and contains contributions from the Zoominfo Community.
Is this you? Claim your profile.
+ Get 10 Free Contacts a Month
Please agree to the terms and conditions
I agree to the Terms of Service and Privacy Policy. I understand that I will receive a subscription to ZoomInfo Grow at no charge in exchange for downloading and installing the ZoomInfo Contact Contributor utility which, among other features, involves sharing my business contacts as well as headers and signature blocks from emails that I receive.
101 N Tryon St, 5th Fl
Charlotte, North Carolina 28255
United States
Bank of America Merrill Lynch offers industry-leading support to small and middle-market businesses as well as large corporations with a full range of banking, investing, asset management, and other financial and risk management products and services. ... more
Gary Gordon AAA
AAA Global Solutions Ltd
Ed Kearney AAA
AAA Global Solutions Ltd
Kirk Aaa
Automobile Club of Southern California
Steve Barton AAA
AAA Global Solutions Ltd
Bw Aaa
AAA Hotel Company


text:
Skip to Content
Home > Research > Research Centers & Programs > Center for Rehabilitation Outcomes Research (CROR) > Research Projects > Midwest Regional Spinal Cord Injury Model System of Care Database (MRSCICS)
Why is this study needed?
This study is part of a national research project designed to learn more about the issues and concerns of people with spinal cord injury (SCI). Our goal is to improve outcomes and quality of life for people with SCI and their families by tracking the long term health of people who have been patients at the Rehabilitation Institute of Chicago.
What are the project objectives?
What agency funded the project?
The National Institute on Disability, Independent Living, and Rehabilitation Research (NIDILRR)
What is the duration of the project?
October 1, 2016 – September 30, 2021.
Principal Investigator:
David Chen, M.D., Medical Director, Spinal Cord Injury Acute Care and Rehabilitation
Allen Heinemann, Ph.D., Program Director, Rehabilitation Institute of Chicago
RIC Project Manager:
Allison Todd
Related Project Research Web Sites
National Institute on Disability, Independent Living, and Rehabilitation Research
National Spinal Cord Injury Statistical Center
Model Systems Knowledge Translation Center
Contact information
For research and students:
Allen Heinemann
For members of the media
345 E. Superior Street - Chicago, IL 60611 | 1-800-354-REHAB (7342) | 312-238-1000
©2017 Rehabilitation Institute of Chicago. All rights reserved.


text: My company (part of our health clinic focuses on herbal food concentrates and not medicinal type herbs and supplements) has announced it is the sole sponsor of the 2006 Israel Olympic Team. Sunrider International is the largest food-herb company in the world (second largest number of stores to Walmart) and is supplying all the products needed for training, etc for the team. They are going out on a limb. Sunrider is very popular in Indonesia, China, Korea, etc - places that are NOT friends of Israel.


text:
Titchmarsh Tree Surgeons
fencing in surrey
Titchmarsh Tree Surgery provides competitive quotes for fencing work and prices include the dismantling, removal and disposal of old fencing. We generally give our customers the freedom to choose their own fencing but we can supply for you if required.
Email - none provided
Print this page
The Titchmarsh Tree Surgery is a trusted provider of tree care and garden maintenance services as well as we cover
Create your free Hotfrog business profile
Follow Hotfrog on:
Share on:
Hotfrog Small Business Hub


text:
April 14, 2011 | 1 comment
Terms of new online store enable Amazon to maximise market share at expense of game devs' profits, warns trade body. Read More »
Sorry, no posts matched your criteria.
Download experimental Cinema 4D plugins and scripts for free from Maxon's new online repository. Read more »
February 18, 2017
New integration plugin for the GPU renderer supports Houdini's native primitives, instancing and volumes. Read more »
Update improves texture streaming and tonemapping, adds support for Nintendo Switch and HDR displays. Read more »
February 16, 2017
Real-time rendering toolkit gets support for material animation, new refraction shader, and EXR output. Read more »
Concept artist Eliott Lilly reveals the 10 key questions to ask yourself to plan a successful long-term career. Read more »
January 19, 2016 | 2 comments
© CG Channel Inc. All Rights. Privacy Policy.
CG Channel is part of the Gnomon group of companies:


text:
Is Groote Kerk incorrect or missing key business information? Update your Hotfrog listing today.
Contact details
Are these details correct?
Hotfrog SouthAfrica provides information regarding Groote Kerk in Cape Town Western Cape. Groote Kerk is located at 43 Adderley St, Cape Town Western Cape 8001 and provides Churches services. Contact them on 021 422 0569 or by visiting them on their website http://www.grootekerk.org.za/.
Is Groote Kerk in 43 Adderley St, Cape Town Western Cape 8001 your business? Claim your listing and attract more leads by adding more content, photos and other business details.
We have more Churches services in Cape Town Western Cape available on Hotfrog SouthAfrica. You can update your search for Cape Town Churches by location, keyword or service options.
1ST FLOOR SPENCER HSE Cape Town Western Cape 7405
HILLCREST ESTATE, RACE COURSE ROAD Cape Town Western Cape 7550
Unit 2 Cavi Park, 2 Estoril Road, Killarney Gardens Cape Town Western Cape 7441
7 SONSKYN ROAD BELLVILLE Cape Town Western Cape 7530
Small Business Hub
Sharing tips, ideas and advice to help grow your small business.
Your profile without ads
Have you considered upgrading to Hotfrog AdVantage? No competitor advertising means exclusive focus on your business. You take centre stage.
Create your free Hotfrog business profile
Follow Hotfrog on:
Share on:
Hotfrog Small Business Hub


text:
Silfra Tectonic Course
An unusual dive certification
Iceland is a beautiful and strange place to dive, presenting you with new experiences and considerations when taking the plunge.
Cold water diving requires a different set of skills than warm water. For instance, to be a competent dry suit diver you must be able to control your buoyancy, clear air from your feet, and remove your dry suit inflator hose and replace it.
DIVE.IS instructors have taught the PADI Dry Suit Course on an almost weekly basis for years. During the summer season we have both enough daylight and good weather to be able to run our standard one day Dry Suit Course, whilst guarenteeing you a course to the highest quality. This course also gives you the opportunity to complete at least one of your training dives in the beautiful Silfra.
The course is structured as follows:
During the Confined session your instructor will introduce you to diving in a drysuit, including donning, care, bouyancy control skills and emergency avoidance skills. You will then move on to your open water dive site where you will have to practice these skills again at a deeper depth and different environment.
The course has a maximum of three students per instructor, which gives each student the greatest individual attention. With training over a variety of dive sites this dry suit course provides a sturdy basis for all of the cold-water dives that you will undertake in the future.
Please note that participants are not allowed to bring any type of camera into the water on the course. This is prohibited by PADI standards.
Visit our website on dry suit diving.
Available from February 15th – October 15th.
Please check the booking calendar below for scheduled courses.
This course might also be available on request from February to October.
Prior to beginning participants must:
10-12 Hours on a single day
Minimum 2 divers.
Maximum 3 divers per guide.
The PADI Dry Suit Manual is excluded from the course price and costs ISK 5.590,- extra at our dive centre.
You will need to complete the knowledge development in the Dry Suit Manual prior to the course. You are welcome to either purchase the manual from us or from your local PADI Dive Centre. If you buy it from us, please be sure to come pick up your dry suit manual at least one day in advance of your course so that you have enough time to read it.


text:
Comment Re:So even worse than before? (Score 1) 139
To be fair the screenshot was pretty clear where the limits of the application are, with less dead screen area. Something that i'm finding increasingly annoying.
Take PDF files for example, why are they Portrait when most screens are landscape? The font sizes are designed for a page size typically 50% taller than your screen. So getting a page on screen means the fonts are uncomfortably small. The next issue is margins typically an inch round the page is white space! For a bit of paper that is fine we don't want to be reading into the spine of a book and we don't want ink transferring to our fingers. But on a screen it already has a bezel margins are just doubling up on margins and making the content smaller and harder to read.
The real failure is when you just give up and print out the page
So Yeah i'm in favour of making better use of screens and you don't need to draw borders round things a small difference in tone or texture is enough. maybe not even that usually if you need to write in a text area the cursor goes to the top left position any way.
I detest the downward scroll that we seem obsessed with if there isn't enough space on the first page make a second page. it's simple.


text:
Al Yankovic's latest song, White and Nerdy, is all over the blogs, obviously hitting a key demorgraphic. AOL pulled the 'World Premiere' as it had been leaked online already – there's currently 21 entries on YouTube for the same video. By looking at the viral video charts today, 2 of the YouTube versions actually have higher links than the 'official' one on MySpace.
The video chart itself is interesting in that it often shows up the multiple versions of a single piece of content often on different netowrking sites, so you see stuff being popular on YouTube, then MySpace, then Google video, rolling in waves across the networks and back as different 'groups' get hold of them. Some one far better at coding than I could do some cool things with the data, showing the trends across the sites.
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.


text:
|Visitors Now:
|Total Visits:
|Total Stories:
|Story Views
|Last Hour:
|Last 24 Hours:
Shares in MGX Minerals Inc (CNSX:XMG) opened higher after it completed infill and extension diamond drilling at its flagship Driftwood Creek magnesium deposit.
The drilling program successfully intercepted large intersections of magnesite mineralization consistent with past drilling and three-dimensional modelling.
Step out drilling has intercepted magnesite mineralization along strike both to the East and West ends of the known resource, MGX told shareholders.
The drill program was increased to a total of 16 drill holes, totaling 1,211 metres with lengths ranging between 31 and 184 metres.
In total, 386 split core samples were shipped for whole rock geochemical analysis.
Results will provide further information for the preliminary economic assessment of the asset in British Columbia, and should not only reveal potential economic extraction, but also a revised resource estimate.
This is the third diamond drill program completed by MGX at Driftwood, in addition to 100 tonne bulk sample completed in June 2016.
Shares in MGX opened 3.3% higher at CS$0.155 on the news.
Story by ProactiveInvestors


text:
Listing information
- Year Built: 1996
- Status: Sold on 9/3/2014
- New Construction: No
- Above Ground Sq. Feet: 1,200
- Estimated Annual Taxes: $1,516
- Middle School: Lakeshore
- Subdivision: N26 - Robinson Township
- Property ID: 103832322
- Beds: 3
- Stories: 0
- Foreclosure: No
- Lot Area: 1.14
- County: Ottawa
- Elementary School: Robinson
- Style: Residential
- Baths: 2 (Full: 1 3/4: 0 1/2: 1 Other: 0)
- Parking Type Description: Attached 2 cars
- Total Square Footage: 1,488 ($110.82 per sq. foot)
- Lot Size: 262x183
- High School: Grand Haven
- School District: Grand Haven
Additional Items Ceiling Fans, Central Vacuum, Garage Door Opener, Water Softener/Owned
Air Conditioning Central
Appliances Dishwasher, Microwave, Oven, Range, Refrigerator
Basement Yes
Design Ranch
Driveway Paved
Exterior Features Deck(s), Scrn Porch
Exterior Material Vinyl
Fireplace Bathroom, Kitchen, Living, Master Bedroom, No, Other Bedroom, Rec Room
Garage Type 2, Attached
Garage: Garage Yes
Heat Source Natural Gas
Heat Type Forced Air
Kitchen Features Eating Area
Landscape Flower Garden, Ground Cover, Shrubs/Hedges
Lot Description Cul-De-Sac, Wooded
Manufactured: Manufactured Y/N No
Other Basement Rooms: Basement Finished SQFT - 288.00, Basement Rooms: Total Basement SQFT - 1200.00, Main Rooms: Main Bedrooms - 3, Main Rooms: Main Full Baths - 1, Main Rooms: Main Half Baths - 1, Main Rooms: Main Level SQFT - 1200.00, Road Frontage - 262.00
OUTBUILDINGS Pole Barn, Storage Shed
Property Sub-Type Single Family Residence
Roofing Comp Shingle
Sale Conditions None
Street Type Unpaved
Substructure Full Basement
Terms Available Cash/Conventional, FHA, Rural Development, VA
Util Avail at Street Broadband, Cable
Utilities / Sewer Septic System
Utilities Attached Cable, Natural Gas, Telephone Line
Water Well
Waterfront Options: Waterfront Y/N No
Windows Insulated
Bedroom 2 M 10x10
Bedroom 3 M 9x10
Kitchen M 12x8
Laundry Room M 10x7
Living Room M 19x13
Master Bathroom M 8x12
Master Bedroom M 11x12
Dining Area 9x12
Listed by Greg Martin of Coldwell Banker Schmidt REALTORS 616-844-9000


text:
Whitehouse Jamaica
Whitehouse Jamaica is a small, unassuming village on the southwest coast of the island. Traditionally, the primary local economy of this town has been fishing. However, the opening of the Sandals Whitehouse European Village and Spa in 2005 has turned this quiet town into a popular island destination because this is one of the very popular Jamaica resorts.
One of the major attractions to Sandals Whitehouse Jamaica is its position within 500 acres of protected Jamaican wilderness. Typical Sandals opulence is surrounded with fertile mountains and clear waters, making this resort especially unique. It is normal to stroll the white sands of Whitehouse Beach, also known as Two Mile Beach, in isolation, without the usual commotion common to other beaches of Jamaica.
Sandals Whitehouse Jamaica is modeled after some of the most popular European destinations. There are three separate villages offering Italian, French, and Dutch architecture and charm. Rooms and villas meet the impeccable standards expected of Sandals resorts, including a view of the ocean, all-inclusive amenities, and in some cases, personal butler service. The grounds are modeled after Italian piazzas, complete with fountains and gardens.
Guests of Sandals Whitehouse are welcome to take advantage of the many activities offered by the resort. There are four pools to choose from, and the beach is fully stocked with complimentary chairs and towels. Water sports rentals include PADI-certified scuba diving, snorkeling, kayaks, and windsurfing. Other activities include beach volleyball, billiards, tennis, and aerobics classes. The resort's guided tours whisk guests away to take in the beauty of Jamaica in unique ways, such as zip lining in the jungle and swimming with dolphins. Those wishing to fully relax can take in a massage at the Red Lane Spa. After a full day of relaxation, guests have seven restaurants throughout Sandals Whitehouse to choose from, including those serving Italian, Asian, and Parisian cuisines. Guests can also enjoy a nightcap at the piano bar or dance the night away at the nightclub.
Compare Travel Sites and Save!
Dunns River Falls
Dunns River Falls Jamaica regularly tops lists of the world's most beautiful ...
Bob Marley Museum
The Bob Marley legend lives on at the Bob Marley Museum in Kingston Jamaica. ...
Latest Topics
My recent trip & report from Hedonism II resort in Negril
My (late) Trip Report from my June 2016 Hedonism II resort adventure) My most recent trip (Jun...
Things to do in Jamaica
For first time travelers to Jamaica, what activities are there to do besides swimming, fishing, a...
Montego Bay
This week Montego Bay is one of the featured destinations on the home page of Destination360.com....


text:
Плагин служит для подключения на другой сервер по указанному IP. Его можно указать в исходнике
Название игры: S.I.P: Out Life Жанр: FPS, с элементами RPG Язык: с++, скрипты lua G API: DirectX 9 Сайт: sip-game.su Группа Vk: vk.... Читать далее
This mod adds custom armor, weapons, a unique stallion, re-textured steel horse armor (if you have the official DLCHorseArmor mod), historical book with a map and 4 unique types of creatures that guard the legendary equipment. For more details, purchase and read the book called "Lost Paladin of the Divines."
Paladins Rejoice!
Music Add-on: Link
WARNING: Playing this mod may scare children and unstable adults. Side effects include, but are not limited to, being scared of the dark and looking over one's shoulder.
The book called "Lost Paladin of the Divines" can be purchased at the First Edition in the Market District of Imperial City.
Once you obtain the unique equipment called Heaven's Wrath and Heaven's Fury, you will be able to buy lesser non-enchanted replicas at The Best Defense and A Fighting Chance.
If you defeat the final guardian, you will be rewarded with a Paladin's Stallion as a gift from the Divines.
If you defeat the final guardian and have no infamy points, you will be able to open the Crypt of Vralen Averos and will be presented with a series of questions to customize the Heaven's Wrath Armor set.
This 2nd reward is an enchanted heavy armor set called Heaven's Wrath and includes:
- Heaven's Wrath Helmet (Open or Closed is your decision)
- Heaven's Wrath Cape
- Heaven's Wrath Cuirass (Male and Female)
- Heaven's Wrath Gauntlets
- Heaven's Wrath Greaves
- Heaven's Wrath Boots
- Heaven's Wall (Heavy Shield)
- Heaven's Glory (Longsword - With or without golden-colored flames that give off light)
- Heaven's Messenger (Claymore)
- Vralen's Journal Note (clue to the location of Heaven's Fury light armor set)
- A vendor at the Best Defense in the Imperial City will craft and sell a replica set of the heavy armor.
- A vendor at a Fighting Chance in the Imperial City will craft and sell a replica set of the swords.
- A vendor at the Divine Elegance in the Imperial City will craft and sell replica capes.
If you read Vralen's Note titled "Heaven's Fury Note," you should be able to figure out the location of his original and light armor set called Heaven's Fury. Once you find the ruin described in the note, it's just a matter of time searching for the chest called "Chest of Vralen Averos" which includes:
- Heaven's Fury Helmet (Open or Closed is your decision)
- Heaven's Fury Cuirass (Male and Female)
- Heaven's Fury Gauntlets
- Heaven's Fury Greaves
- Heaven's Fury Boots
- Heaven's Gate (Light Shield)
- A vendor at the Best Defense in the Imperial City will craft and sell a replica set of the light armor.
Other items include:
- Official DLCHorseArmor texture replacer for the Steel Armor.
- Several colored crystal ball lamps located in the same ruins of Heaven's Wrath.
- Valuable and rare collector portraits of Vralen Averos and Galandra Laora.
- Four levels of Werewolf creatures that act as guardians for the armor. Each breed is visually different and leave behind new and varied ingredients. The deeper you go into the ruin, the more difficult they become.
The unique weapons found during the quest are equivalent to Daedric weapons.
The Replica weapons found in vendor shops are equivalent to Elven weapons.
Heaven's Wrath armor is equivalent to heavy Daedric armor.
Heaven's Wrath replica armor is equivalent to heavy Orcish armor.
Heaven's Fury armor is equivalent to light Glass armor.
Heaven's Fury replica armor is equivalent to light Mithril armor.


text:
Hurley Real Estate
Hurley is located in Mississippi. Hurley, Mississippi has a population of 1,626. Hurley is more family-centric than the surrounding county with 43.5% of the households containing married families with children. The county average for households married with children is 31.15%.
The median household income in Hurley, Mississippi is $58,625. The median household income for the surrounding county is $49,750 compared to the national median of $53,046. The median age of people living in Hurley is 32.6 years.
Hurley Weather
The average high temperature in July is 91 degrees, with an average low temperature in January of 40.8 degrees. The average rainfall is approximately 69.6 inches per year, with 0.1 inches of snow per year.
Hurley Map
Hurley real estate offices
Real estate near Hurley
Nearby Cities
Hurley Zip Codes


text:
"Nice suites" Scandic Hotel Marski Tip by heikkiko
Scandic Hotel Marski, Helsinki: 1,101 reviews and 12 photos
Was there with my love for a weekend. Had booked a premium room but got a suite instead!
The staff was friendly and helpfull.
Address: Mannerheimintie 10, Helsinki FIN-00100
Price Comparison: about average
Phone: +358 3 58968061
Price: US$180 and up
Theme: Hotel
Website: http://scandichotels.com/marski
1 - 0 of 0
heikkiko's Related Pages
"Borta bra men hemma bäst!"
- No VT rank yet.
- 10 Reviews
- 5 Photos
- Add Friend
- Follow
- Send Message
Have you been to Helsinki?Share Your Travels


text:
Your Paris Holiday Includes:
- Return Economy Class airfares to Paris from Auckland, Wellington & Christchurch
- 3 nights accommodation
- Daily breakfast
Please note price based on a weekday flight departure from New Zealand (Sunday to Wednesday). For flight departures Thursday to Saturday, please add $55pp
- Tryp Double Room (3 Nights)
- Travel Dates: 24 Feb - 4 Apr 17, 24 Apr - 8 May 17, 20 Oct - 23 Oct 17 & 27 Oct - 31 Oct 17
Twin per person $2,384Extra Nights$150
Single per person $2,834Extra Nights$300
- Travel Dates: 5 Apr - 23 Apr 17
Twin per person $2,540Extra Nights$150
Single per person $2,990Extra Nights$300
- Travel Dates: 9 May - 15 May 17, 19 May - 13 Jun 17 & 5 Oct - 19 Oct 17
Twin per person $2,453Extra Nights$173
Single per person $2,969Extra Nights$345
- Travel Dates: 16 May - 18 May 17 & 24 Oct - 26 Oct 17
Twin per person $2,756Extra Nights$274
Single per person $3,578Extra Nights$548
- Travel Dates: 14 Jun - 18 Jun 17, 2 Sep - 17 Sep 17 & 21 Sep - 25 Sep 17
Twin per person $2,609Extra Nights$173
Single per person $3,125Extra Nights$345
- Travel Dates: 19 Jun - 22 Jun 17 & 18 Sep - 20 Sep 17
Twin per person $2,912Extra Nights$274
Single per person $3,734Extra Nights$548
- Travel Dates: 23 Jun - 2 Jul 17
Twin per person $2,815Extra Nights$173
Single per person $3,331Extra Nights$345
- Travel Dates: 3 Jul - 5 Jul 17
Twin per person $3,118Extra Nights$274
Single per person $3,940Extra Nights$548
- Travel Dates: 7 Jul - 31 Aug 17
Twin per person $2,746Extra Nights$150
Single per person $3,196Extra Nights$300
- Travel Dates: 26 Sep - 1 Oct 17
Twin per person $2,780Extra Nights$230
Single per person $3,470Extra Nights$460
- Travel Dates: 2 Oct - 4 Oct 17
Twin per person $2,624Extra Nights$230
Single per person $3,314Extra Nights$460
Per Person, from $2,384Enquire Now
Closeout and blackout periods apply over school holidays and peak holiday periods & availability of seats & rooms is likely to be very limited over this time.
It is our policy to present the cost of our holidays inclusive of all airport and government charges. Please accept however that these charges are not within our control, therefore we reserve the right to pass on any increase.. Travel agent professional service fees where charged, will be additional to the advertised prices. Payment & ticketing deadline - no more than 14 days after reservation confirmation. Please note that any Airline generated ticketing time limit which is earlier will over-ride this. Valid for sales to 6 Mar 2017. Valid for travel commenced on or after 24 Feb 2017 (unless otherwise specified). Min Stay: 7 days Max Stay: 4 months.Prices are ex Auckland, Wellington or Christchurch. Travel is based on economy class airfares on Emirates (T class) from AKL, WLG or CHC to Paris (CDG) via MEL/SYD/BNE and DXB. Capacity is strictly limited. IMPORTANT: A surcharge of NZD$55 applies for outbound travel on a Thursday, Friday and Saturday. A Surcharge of NZD$218 applies to outbound travel from 06-08 JUL 17. QF OPERATED SURCHARGES QF009 - NZD$218 OUTBOUND 15JUN-17JUN / 22JUN-24JUN17 QF001 - NZD$218 OUTBOUND 22JUN-24JUN / 28JUN-01JUL17. QF002/QF010/EK5002/EK5010/EK5052 - $109 INBOUND 07JUL-21JUL17 / 02JAN-26JAN18 / 07JUL-21JUL18. QF002/QF010/EK5002/EK5010/EK5052 - $163 INBOUND 27SEP-19OCT17 / 27SEP-19OCT18. Blackouts: T Class low & shoulder season fares - Inbound travel not permitted 19Jul17-26Jul17. T class fares using QF002/QF010/EK5002/EK5010/EK5052 - Inbound travel not permitted 07Jul-31Jul17 / 28Sep-19Oct17 / 09Dec-23Dec17 / 02Jan-15Jan18 / 07Jul-31Jul18 / 28Sep-19Oct18. . Capacity Limitations: Availability may be limited and not available all flights. Upsells may be required depending on direction and month of travel, especially Jun-Aug in lower booking classes and during peak Dec-Jan periods. Please ensure the following OSI entry is entered at time of PNR creation: OSI ZZITX2ZZ failure to do so will result in PNR's defaulting to published retail TTL. All ticketing must be completed within the below TTL's. Booking made 355-7 days prior to departure must be ticketed within 14 days after booking or 7 days before departure whichever is earlier. PLEASE NOTE: where any ticketing message is generated which differs from the above the most restrictive deadline will apply. All ticketing to be completed by 06 MAR 17 - NO exceptions. Valid on EK flights operated by EK/QF/JQ/BE. Valid of QF flights operated by QF. Valid on JQ flights operated by JQ. QF200-399 flight numbers not permitted. Travel not permitted on the following EK6200-6299/EK6670-6671/EK6680-6681/7200-7299 code share flights. Travel between BKK-HKG v.v is not permitted on any EK flight. JQ6000-6999 flight numbers not permitted. Stopovers - 1 free stopover permitted in each direction. Additional stopovers permitted at NZ$163 per stop. Note: Stopovers permitted at any transfer point as per route map in GDS. All fares are subject to increase or withdrawal without notice. For full rules/conditions/cancellations please refer to the GDS. Credit cards are not permitted. Change, reissue & cancellation fees apply. SKYWARDS SAVER miles are accruable on EK sectors with the above fares. Accommodation Surcharges apply during Trade Fair periods. A Paris City Tax applies & is paid direct to the hotel: EUR1.65 per person per night for 3 star hotels, EUR2.48 per person per night for 4 star hotels and EUR3.30 per person per night for 5 star hotels. Prices shown are based on per person costs in New Zealand Dollars, for payment by cash, cheque or eftpos only. Credit card sales not permitted unless Travel Agent acts as a merchant. Capacity limitations apply and may not be available on all services. Travel requiring an overnight stay in New Zealand will be at passengers own expense. Events beyond our control such as currency fluctuations and changes to the price of aviation fuel may result in prices variations . Strict cancellation fees apply. Packages are based on consecutive nights. For split stays please contact your travel consultant. For full terms and conditions and cancellation fees please contact your local travel agent for more information. AFC: JQ / JR ISSUED: 14FEB17.
GO Ref# EK14FEBGEG


text:
Is Kc Carpenter incorrect or missing key business information? Update your Hotfrog listing today.
Contact details
Are these details correct?
Hotfrog Singapore provides information regarding Kc Carpenter in Singapore. Kc Carpenter is located at No. 62 Ubi Rd 1, Singapore 408734 and provides Home Improvement services. Contact them on 9384 4408 or by visiting them on their website http://www.kccarpenter.com.sg.
Is Kc Carpenter in No. 62 Ubi Rd 1, Singapore 408734 your business? Claim your listing and attract more leads by adding more content, photos and other business details.
We have more Home Improvement services in Singapore available on Hotfrog Singapore. You can update your search for Singapore Home Improvement by location, keyword or service options.
Small Business Hub
Sharing tips, ideas and advice to help grow your small business.
Create your free Hotfrog business profile
Follow Hotfrog on:
Share on:
Hotfrog Small Business Hub


text:
Ofsted and the SENCO: the new framework and expectations
Actions and Detail Panel
Ofsted and the SENCO: the new framework and expectations
Thu 20 April 2017, 09:00 – 15:30 BST
Event Information
Date and Time
Friends Who Are Going
Connect to Facebook
Friends Attending
Friends Attending
None yet
- Settings
Friends Attending
Whoops! Couldn't connect
- Settings
This course will give senior leaders and SENCos in mainstream primary and secondary schools a better understanding of Ofsted's new national expectations with regard to outcomes for disabled pupils, those with special educational needs and those with mental health needs.
There will be an update for SENCos and senior leaders on the most recent requirements for the provision for disabled pupils and those with special educational needs in mainstream schools. In line with the revised code of practice, the role of the SENCo will be clarified along with ways to manage and develop appropriate training programmes to equip teaching and support staff.
Delegates will learn about:
- supportive classroom environments for all pupils
- developing roles in leading and managing provision and supporting staff
- the role of the SENCo and senior leaders in monitoring and supporting provision and impact/outcomes for pupils' achievement, personal development, behaviour and welfare
- measuring progress and achievement for pupils including those with profound needs
- the difference between underperformance and special educational needs
- additional or different arrangements that lead to an improvement in progress
- guidance on restraint
- developing effective links with the governing body and the link governor
For this course you will need to bring a printed copy of Ofsted's most recent School inspection handbook.
Course facilitator: Terry McKenzie
Members of NAHT can enjoy our courses and conferences at a subsidised rate so join here today and start enjoying the benefits of membership
Please note that the start time shown allows for registration and refreshments, the course programme will be sent to each delegate via the email supplied with the final information.
Please do not book travel or accomodation without checking with the Professional Development team on email@example.com that the course will be going ahead.
The NAHT has the right to cancel the course if insufficient bookings are received.
By booking a place you are accepting NAHT's terms and conditions.
Do I need my membership number to book?
Yes. If you are booking a member place you will be required to enter the correct membership number. You can find your membership number by phoning membership on 0300 3030333 option 2.
Where can I contact the organiser with any questions?
The Professional Development team can be contacted on email@example.com or 01444 472405.
Is my booking transferrable?
Bookings may only be transferred at the discretion of the Professional Development team. These will need to be made in writing to firstname.lastname@example.com before the event. Transfers and cancellations may be subject to a charge.
Cancellation fees:
Within 20 working days - 25% charge
Within 10 working days - 50% charge
Within 5 working days - 75% charge
Within 2 working days - 100% charge
Can I update my registration information?
Any updates to your booking must be made in writing to the Professional Development team at firstname.lastname@example.com
Does the name on the booking need to match the attendee?
The names of each individual attendee must be entered during the booking process along with a unique email address for each attendee as this will be used for the final confirmation.
Date and Time
Friends Who Are Going
Connect to Facebook
Friends Attending
Friends Attending
None yet
- Settings
Friends Attending
Whoops! Couldn't connect
- Settings


text:
The Photo Game Face feature on Persona Tiger Woods PGA Tour 08 allows you to capture and upload a photo of yourself to use as your player's avatar when you have an EA Sports World account. To capture a picture of yourself from your console, you will need a digital camera and USB cable. You can also upload a picture from your EASportsworld.com account to use as your Photo Game Face picture.
- Skill level:
- Easy
Other People Are Reading
Things you need
- Digital camera
- USB cable
- Xbox 360 or PS3
Show MoreHide
- 1
Log in to your EA Sports World account.
- 2
Click on "My Tiger 08" from the main menu.
- 3
Click on "Photo Game Face" and then "Create Photo Game Face."
- 4
Choose the gender you want your custom player to be.
- 5
Click on "Get Photo." If you are using Microsoft Xbox 360, select "Xbox Live Vision." If you are using Sony PS3, select "USB Camera." If you want to upload a photo from your EASportsworld.com account, select "Download from the Web."
- 6
Follow the on-screen instructions to finish capturing and uploading your photo.
Don't Miss
- 20 of the funniest online reviews ever
- 14 Biggest lies people tell in online dating sites
- Hilarious things Google thinks you're trying to search for


text:
Oakwood is located in Hall county and has a population of 2,689.
The average in-state tuition for full time undergraduate students in wedding planning schools in Oakwood during the 2009 - 2010 school year was $1,896.00. The average tuition was $5,773.00 for non-residents studying in Georgia.
Books and supplies for wedding planning schools in Oakwood cost an average of $1,100.00. There is one wedding planning college in Oakwood. 7 students were reported to have graduated from wedding planning programs in Oakwood in the 2008 - 2009 school year.


text:
Course Number: 13186 – 6
Instructor: Yasmin Solomonescu
"[T]here will be time," writes T. S. Eliot in "The Love Song of J. Alfred Prufrock," "time yet for a hundred indecisions, / And for a hundred visions and revisions, / Before the taking of a toast and tea." While this seminar doesn't promise toast and tea (although that's negotiable), it does promise a feast of literary works well worth digesting, specifically ones about the many "visions and revisions" involved in literature itself. Through the study of poetry, plays, and a novel from across centuries, we will become acquainted with literature as a mode of expression that involves artful negotiation with one's cultural and historical heritage, notably through adaptation, echoing, imitation, and allusion. We will also explore the ways in which literature is often on some level about its own visionary and revisionary processes. The seminar will feature regular classes in which we analyze, discuss, and practice the critical visions and revisions involved in thinking and writing about literature at the university level. Writers figuring prominently in the syllabus include Shakespeare, Stoppard, and Woolf.


text:
Back in April, Boulder's eTown radio program announced that it received a grant from the Fort Collins-based organization, the Bohemian Foundation. The "challenge grant" meant the foundation would match any donations made to the development of eTown Hall, a new venue, recording studio and community space that would cost $5.5 million.
It's been about six months, and construction of the new space is well underway in an old church at the corner of 16th and Spruce Streets. The bulk of the remaining work is in the venue space -- eTown is already moved in and doing post-production, editing and administrative work from the new offices.
The Morning Email helps you start your workday with everything you need to know: breaking news, entertainment and a dash of fun. Learn more


text:
Is Idc Manpower Services incorrect or missing key business information? Update your Hotfrog listing today.
Contact details
Are these details correct?
Hotfrog Philippines provides information regarding Idc Manpower Services in San Juan Metro Manila. Idc Manpower Services is located at Annapolis Street, San Juan Metro Manila 1503 and provides Employment Agencies services. Contact them on (02) 726 7567.
Is Idc Manpower Services in Annapolis Street, San Juan Metro Manila 1503 your business? Claim your listing and attract more leads by adding more content, photos and other business details.
We have more Employment Agencies services in San Juan Metro Manila available on Hotfrog Philippines. You can update your search for San Juan Employment Agencies by location, keyword or service options.
Small Business Hub
Sharing tips, ideas and advice to help grow your small business.
Create your free Hotfrog business profile
Follow Hotfrog on:
Share on:
Hotfrog Small Business Hub


text:
P3 Heating Services51 Feedback reviews, 98% positive
reliable heating engineer with over twelve years of experience on english market, registered and with full liability insurance , reg nr 221267, certificates, fix and comlete upgrade projects for all kind of domestic commercial and industrial instalations,
Latest Gas Work feedback review:
By rb1225 on 23rd Jun, 2014
M A Plumbing16 Feedback reviews, 100% positive
M A Plumbing specialise in all aspects of plumbing and ceramic tiling including bathroom fitting. We offer a high quality service to customers in Southampton and surrounding areas. Our services range from a small maintenance job to a complete bathroom installation.
Latest Gas Work feedback review:
By maxine_159 on 28th Jan, 2017
MayDay Heating & Plumbing22 Feedback reviews, 100% positive
I am a Gas Safe registered engineer, trained in the installation, repair and service of Boilers, Fires and Cookers. I also work on the plumbing side of things from a dripping tap to fitting radiators. I also install heating parts like magnetic and limescale filters, and...
Latest Gas Work feedback review:
By violetdoll on 15th Feb, 2017
Reeve Heating and Plumbing Services12 Feedback reviews, 100% positive
A friendly, reliable and affordable service. All heating works from installation, servicing, unvented cylinders and breakdowns. Most plumbing work undertaken from leaks to toilet replacements. Guttering work also. Gas safe registered and have over 10 years...
Latest Gas Work feedback review:
By alison_570 on 27th Jun, 2016
RT. Hydro Plumbing & Heating32 Feedback reviews, 100% positive
I am a clean, reliable plumber and heating engineer! Fully insured always ready for work 24/7. Reasonable rates and City and Guilds qualified to NVQ Level 2. All work is carried out to the highest of standards. I can cover all your plumbing and heating needs and more.
Latest Gas Work feedback review:
By leiberman on 4th Nov, 2016
Ls Property Maintenance Ltd3 Feedback reviews, 100% positive
Hi I'm fully qualified gas registered plumber and heating engineer. My company name is ls property maintenance Ltd. All my work is carried out professionally and in very high standard. Always on time and reasonable prices.
Latest Gas Work client reference:
Reference taken by MyBuilder on 11th Feb, 2016
New Age Plumbing And Heating2 Feedback reviews, 100% positive
I am a hard working knowledgeable plumber and gas engineer, I have been working in the construction trade for the last 10 years in that time I have gained a wealth of experience. I have recently setup my own business which will benefit customers as I can build better...
Latest Central Heating feedback review:
By michael_705 on 16th Mar, 2016
Lyver Plumbing2 Feedback reviews, 100% positive
I am a Gas Safe registered heating engineer & Family run business based in Winchester covering Otterbourne and surrounding areas. Specialise in all aspects of heating & plumbing, providing a friendly & reliable service.
Latest Central Heating feedback review:
By khc_11 on 7th Sep, 2015
Winchester Boilers & Gas Services2 Feedback reviews, 100% positive
Winchester boilers & gas services specialise in boiler breakdowns, servicing, boiler installations and all aspects of gas related work. Customer satisfaction is our number one priority. You can find us on "Checkatrade" with over a 100 positive feedback ratings.
Latest Gas Work feedback review:
By jennjamm on 10th Jan, 2017
Plumb Tek21 Feedback reviews, 100% positive
Plumb Tek is an established business which delivers a reliable and fast service. Our excellent customer relations, professional knowledge and quality of workmanship have resulted in an ever growing first-rate reputation. We are members of Checkatrade,Gas safe & Trading...
Latest Gas Work feedback review:
By neville980 on 8th Jan, 2017
David Ebbs Plumbing and Heating14 Feedback reviews, 100% positive
I am a friendly local Gas safe registered Plumber, with 14 years experience of working to improve peoples homes across Hampshire and the south coast. I work in a tidy efficient way to exceed customers ambitions whist remaining cost efficient.
Latest Gas Work feedback review:
By chrisallen_79 on 3rd Feb, 2017
Chris Dwyer9 Feedback reviews, 100% positive
I am a gas safe registered engineer. I fit and repair boilers, gas fires, gas and electric cookers and hobs. . I also carry out all smaller plumbing jobs.
Latest Gas Work feedback review:
By debracross62 on 12th Jan, 2017
C.S Plumbing + Heating30 Feedback reviews, 100% positive
C.S plumbing + heating, offers a Professional and Friendly Service to all of our customers. With 5 years experience of all gas work and general plumbing, we are keen to assist you in all of your plumbing needs. Wether it be a boiler installation or bathroom being fitted we...
Latest Gas Work feedback review:
By manuzha on 22nd Feb, 2017
1-Gas Plumbing & Heating10 Feedback reviews, 100% positive
We are a local Plumbing and Heating business working across Hampshire. Our sole aim is to help get your plumbing and heating running again smoothly in the shortest possible time. We carry out all repairs, new installations, landlord certificates and annual maintenance...
Latest Tiling feedback review:
By paulfinch_81 on 24th Nov, 2015
KM Plumbing & Heating, Bathrooms & Kitchens3 Feedback reviews, 100% positive
We would welcome the opportunity to earn your trust and deliver you the best service in the industry.
Latest Gas Work feedback review:
By lancasterestates on 12th Jun, 2014
Need a tradesman?
Post a job on MyBuilder to find a quality, local tradesperson.
How MyBuilder works
1. Post a job
First, create a job listing for your gas work project. It's quick, easy and free - the first step to finding recommended gas engineers in Lyndhurst.
2. Hire a tradesman
Having met our recommended gas engineers in Lyndhurst and read customer reviews, you're ready to decide which gas engineers to hire.
3. Leave feedback
After your project is successfully completed, you can leave a review for your gas engineers. This review helps you and future MyBuilder users.
What our customers say
- " This website is fantastic!! I have been more than happy with the service I have received from the tradesman. Love the site, will use again and again."
- Julie Coyle
Tradesmen in Lyndhurst
- Architectural Designers
- Bathroom Fitters
- Bricklayers
- Carpenters & Joiners
- Carpet fitters
- Chimney & Fireplace Specialists
- Conservatory Installers
- Conversion Specialists
- Damp Proofing Specialists
- Demolition Contractors
- Driveway Pavers
- Electricians
- Extension Builders
- Fascias, Soffits and Guttering Specialists
- Fencers
- Flooring Fitters
- Gas Engineers
- Groundworkers
- Handymen
- Heating Engineers
- Insulation Installers
- Kitchen Fitters
- Landscape Gardeners
- Locksmiths
- Loft Conversion Specialists
- New Home Builders
- Painters & Decorators
- Plasterers
- Plumbers
- Restoration & Refurb Specialists
- Roofers
- Security System Installers
- Stonemasons
- Tilers
- Tree Surgeons
- Window Fitters
- All Tradesmen


text:
Minix 3 and the microkernel experience
Minix Firewall Project
Packet filters are an endangered system component. Despite the excellent quality of the Linux Netfilter implementation, a number of security issues have surfaced in the past. If a subsystem of this kind is running on the Linux kernel, it will endanger system security. Building on work by the Tanenbaum group, the Technical University of Applied Science Berlin ported the widespread Netfilter framework to Minix 3 [5].
Here again, the stability of the microkernel architecture delivers additional benefits. In Linux, an attacker who succeeds in provoking a crash – for example, by exploiting a buffer overflow in the do_replace() function – can bring a Linux firewall to its knees. In Minix 3, a single user process could crash without compromising system security. The reincarnation server would simply restart the process.
The differences become even more apparent if an attacker succeeds in executing code. In Minix, a hijacked user process is still a problem, but the effect is far less serious thanks to isolation.
Even Microsoft is exploring their own microkernel system, named Singularity [6]. Although Minix has played the microkernel game for many years now, its biggest obstacle to becoming more widespread has always been its non-free license. Now that Minix 3 is released under the BSD open source license and the firewall extensions are available under the GPL [7]. Researchers at the TFH Berlin are also working on exploring Minix's potential as a virtualized firewall. Stability, a small footprint, and a new licensing model give Minix 3 a strong potential for growth, especially in embedded systems.
- Tanenbaum, Andrew S., "Some Notes on the 'Who wrote Linux' Kerfuffle, Release 1.5," 2004, http://www.cs.vu.nl/~ast/brown/
- Minix Project: http://www.minix3.org
- Torvalds, Linus, and David Diamond. Just for Fun. HarperBusiness, 2001
- Tanenbaum, Andrew S., and Albert S. Woodhull. The Minix Book: Operating System Design and Implementation. Prentice-Hall, 2006
- Weis, Rüdiger, "Linux is obsolete 2.0," presented at Chaos Communication Camp 2007, http://public.tfh-berlin.de/~rweis/vorlesungen/ComputerSicherheit/WeisLinuxIsObsolete2.pdf
- Microsoft Singularity: http://www.codeplex.com/singularity
- Minixwall: http://wiki.tfh-berlin.de/~minixwall
« Previous 1 2
Buy this article as PDF
(incl. VAT)
Buy Linux Magazine
Visit Our Shop
Direct Download
Read full article as PDF:Minix_3_Review.pdf (924.44 kB)
OpenSUSE Site Hacked
News site for the openSUSE community falls victim to a Wordpress exploit.
LibreOffice Goes Online with 5.3 Release
The source code is available online.
Microsoft Brings Clear Linux OS to Azure
One out of three virtual machines on Microsoft Azure Cloud run Linux.
ASUS Announces a Single-Board Computer
The form factor of the board makes it a drop-in replacement for Raspberry Pi.
Red Hat Releases RHEL 6.9 Beta
Makes it easier for customers to move workloads into container-centric applications.
SUSE Working on a New Operating System Called MicroOS
SUSE's answer to container-centric operating systems.
Biggest Kernel Release Ever
Linux 4.9 is the biggest release in terms of number of commits.
CentOS Linux 7 (1611) Released
The latest version of the official RHEL clone is here.
openSUSE Rolls Out 42.2 Leap
New release targets Linux professionals.
Cutting-Edge Fedora 25 Released
The Fedora project adds Wayland and Gnome 3.22


text:
Snack Safari
this wiki
|This article is about a location in Taiyou Sentai Sun Vulcan and Kaizoku Sentai Gokaiger.
The Snack Safari was the hang-out of the Sun Vulcan team when not on duty. It is run by Daizaburou Arashiyama, where he works as the chef when not controlling his Sentai squadron. Later Sukehachi Yazawa, an actual chef unassociated with Sun Vulcan and the Guardians of World Peace, became an associate chef working to run the restaurant when Sun Vulcan is on duty.
It later appears in the first episode of Kaizoku Sentai Gokaiger. The Gokaigers come here to eat after first arriving on Earth, their lunch was interrupted by an attack from the Zangyack Space Armada, which demolished the diner.
It was rebuilt in time for the Gokaigers to have their final lunch before leaving Earth in the last episode, a few months after they defeated the Zangyack.
- Snack Safari is similar to Snack Gon, the restaurant from Gorenger run by team mentor Gonpachi Edogawa as cover for their Sentai squadron's activities; likewise both Gonpachi and Arashiyama have curry as their store specialty.


text:
(best price)
Raise up to 3.00%.
The Nike Studio Wrap 2 Women's Printed Training Shoes are lightweight and flexible, and can be use from studio to street. The innovative Nike Studio Wrap was designed to help you make the most of workouts typically done... show more
Products you may also like:
Hot Boots (Cream)


text:
|Home | About | Journals | Submit | Contact Us | Français
The level of genomic amplification of the human telomerase gene TERC, which maps to chromosome band 3q26, was determined in primary cervical adenocarcinomas. Interphase nuclei prepared from archival material of 12 primary cervical adenocarcinomas, eight of which were human papillomavirus positive, were hybridised with a triple colour probe set specific for centromeres of chromosomes 3 and 7 and the TERC gene. We observed high proportions of nuclei with increased absolute copy numbers for TERC in all tumours (mean 3.3; range 2.3–5.2). Amplification of the human telomerase gene TERC is a consistent aberration in cervical adenocarcinomas. Therefore, application of our probe set may provide an objective genetic test for the assessment of glandular cells in Pap smears and hence for the diagnosis of cervical adenocarcinomas.
Cervical cancer is a disease that mainly affects women in the forth or fifth decade of life. According to the International Agency for Research on Cancer (IARC), it is the second most common cancer in women worldwide, and in developing nations it is the most common cancer in women (Parkin et al, 2001). Two main types of cervical cancer are described, that is, squamous cell carcinoma and adenocarcinoma. Cervical adenocarcinomas comprise 20% of all cervical cancers that are diagnosed (Vizcaino et al, 1998). Importantly, in the last few decades the incidence of cervical adenocarcinoma among young women has been steadily increasing (Vizcaino et al, 1998; Bergström et al, 1999; Smith et al, 2000; Sasieni and Adams, 2001); however, the reasons for this increase are presently unknown. Applications of clinical screening programmes that have led to a decrease in squamous cell carcinoma have only shown a limited effect on the occurrence of adenocarcinomas. This is owing to the fact that the sensitivity for detecting precursor lesions of adenocarcinomas is much lower than for the detection of precursor cells of squamous carcinomas. This can be partly explained by the difficulty in the morphological assessment of highly differentiated glandular cells, which can be derived from adenocarcinomas of the endocervix. In addition to these difficulties, the endocervix is less accessible for cytological sampling (Bergström et al, 1999).
Epidemiological and molecular biological studies have shown that infection with high-risk human papillomavirus (HPV) is an important aetiological agent in the pathogenesis of cervical adenocarcinoma (Bosch et al, 1995; Bosch and Munoz, 2002). More than 99% of squamous cell carcinomas harbour oncogenic types of HPV, with HPV 16 being the most frequently encountered (Walboomers et al, 1999). Partly in contrast, we and others have found HPV DNA in 30–90% of cervical adenocarcinomas, with HPV 18 as the predominant type (Tenti et al, 1996; Andersson et al, 2003a, 2003b; Clifford et al, 2003; Zielinski et al, 2004; Castellsague et al, 2006).
Although tightly linked to cervical cancer development, HPV infection alone is not sufficient for oncogenic transformation, and other factors than HPV are required for the malignant transformation towards cervical adenocarcinomas (Skyldberg et al, 1999; Pirog et al, 2000). The application of cytogenetic and molecular cytogenetic techniques to study genomic alterations have identified frequent gains involving the long arm of chromosome 3 (Yang et al, 2001). This observation is in concordance with previous findings of recurrent 3q amplification in squamous cell carcinomas (Heselmeyer et al, 1996, 1997a). The value of detection of genomic amplification of 3q as a biomarker for progression during uterine tumorigenesis was therefore evaluated in several studies. The results showed that amplification of TERC is almost invariably found in Pap smears assessed as HSIL (i.e., high squamous intraepithelial lesions). In addition, a more recent study unambiguously established the central role of 3q for progression from low-grade dysplastic lesions to higher grades and to invasive carcinomas and showed that the gain of 3q can occur in morphologically normal Pap smears of women who developed cervical carcinomas after only a short latency (Heselmeyer-Haddad et al, 2003, 2005). Gain of chromosomal region 3q is also recurrently observed in other types of cancer, including tonsillar cancer and carcinomas of the anogenital region that are both associated with HPV DNA (Heselmeyer et al, 1997b; Dahlgren et al, 2003; Stoltzfus et al, 2005).
In this study, we have determined TERC copy number gain in cervical adenocarcinomas using interphase fluorescence in situ hybridisation (FISH) on cytospins prepared from single-cell suspensions of disintegrated archival paraffin-embedded tissue and correlated the findings to the presence of HPV infection and the clinical course.
The study includes formalin-fixed paraffin-embedded tumour tissue specimens from 12 primary cervical adenocarcinomas diagnosed and surgically treated at the Karolinska University Hospital-Huddinge during 1992–2000 (Table 1). All tumour cases were identified from the Swedish Central Cancer Registry organised by the National Board of Health and Welfare. This registry includes all cases of malignant tumours diagnosed histopathologically after 1959, whereby each tumour is identified by a topographical and histopathological code. All tumour samples were collected with informed consent and approval from the local ethics committee.
The clinical information for each case is detailed in Table 1 and has been published previously (Andersson et al, 2003a). The histopathological diagnosis was based on the WHO criteria. The 12 tumours were classified as cervical adenocarcinomas and all were without any squamous cell component. Furthermore, the four HPV-negative tumours (T4, T5, T8, T9) were histopathologically re-evaluated and revealed typical morphology of cervical adenocarcinoma in agreement with the initial diagnosis. Immunostainings with vimentin and carcinoembryonic antigen (CEA) were carried out. Cases T4, T5 and T8 were strongly positive for CEA and negative for vimentin, in agreement with the common pattern for adenocarcinoma of cervical origin as reported by McCluggage et al (2002). Case T9 showed atypical staining pattern (CEA was negative and vimentin positive); however, the morphology was strongly suggestive of cervical origin as judged by several independent histopathologists. Seven tumours were well differentiated (58%), one was moderately differentiated (8%) and four tumours were poorly differentiated (33%). Clinical staging was according to the International Federation of Gynecology and Obstetrics (FIGO) classification for cervical cancer (Benedet et al, 2000). At initial diagnosis, 10 tumours were classified as stage I (83%) and two tumours as stage II (17%). Two patients initially exhibited lymph node involvement (17%). All patients were previously sampled for Pap smear analysis. All but one Pap smear (which was evaluated as showing signs of cellular inflammation) were assessed as normal at the time of the most recent cytological evaluation (Table 1). Re-evaluation of the Pap smears confirmed the initial diagnoses in all cases (Andersson et al, 2003a). All patients were retrospectively followed up from the time of diagnosis until June 2005, and disease recurrence and survival data recorded.
Results from HPV screening analyses have been previously published for all cases (Andersson et al, 2003a). Briefly, the analyses were performed on extracted DNA obtained from sections of paraffin blocks, of which the preceding section had been used for morphological diagnosis. A fragment of 139–148bp was amplified from the L1 region with GP5+/GP6+ primers, HPV typed by direct DNA sequencing and comparison to known HPV sequence databases using the BLAST algorithm (www.ncbi.nlm.nih.gov/BLAST). Eight of the 12 tumours were thus found to be HPV-positive; five tumours were infected with HPV 18, two with HPV 16 and one with HPV 45 (Table 1). In the remaining four tumours, HPV was not detected.
Single-layer nuclei preparations for interphase FISH hybridisations were prepared using the Hedley method with modifications (Castro et al, 1993). A 50-μm section was cut from each of the 12 formalin-fixed paraffin-embedded tumour tissue samples. After deparaffinisation in xylene, the section was rehydrated in an ethanol series and in distilled water, and the section was disintegrated in 500μl of 0.1% protease/1 × PBS (Protease:Type XXIV, Bacterial, P 8038, Sigma, St Louis, MO, USA and Dulbecco's 1 × PBS, Life Technologies, Rockville, MD, USA) at 45°C for 45–60min. The reaction was stopped by adding 500μl 1 × PBS at room temperature. The sample was then filtered through a nylon membrane (CN 051, DAKO, Glostrup, Denmark), centrifuged and resuspended in 1 × PBS. Cytospin slides were prepared using a Shandon Cytospin® centrifuge and fixed in an ethanol series.
Triple-colour FISH analysis was performed on each case using the following probe set: a centromere-specific probe for chromosome 7 (CEP®7); a centromere-specific probe for chromosome 3 (CEP3) and a contig consisting of four overlapping BAC clones containing the TERC gene at chromosomal location 3q26. All probes were obtained from Vysis/Abbott Molecular Inc. (Des Plaines, IL, USA). The details for this probe set, its sensitivity and specificity, as well as experimental conditions were published previously (Heselmeyer-Haddad et al, 2003). In short, CEP7 was labelled with Spectrum Aqua™ (SA), CEP3 with Spectrum Green™ (SG) and the TERC contig with Spectrum Orange™ (SO), using chemical labelling as described (Bittner et al, 1996). Before hybridisation, the cytospin slides were pretreated with a pepsin digestion and fixed in an ethanol series. Slides were denatured in 70% formamide/2 × SSC for 3.5min at 80°C. The probes were denatured according to the manufacturer's recommendations. After overnight hybridisation at 37°C, the slides were first washed four times in 50% formamide/2 × SSC at 45°C (once for 3min and three times for 7min), followed by washes in 2 × SSC at 45°C for 5min and in 2 × SSC/0.1% NP40 at 45°C for 5min. The slides were counterstained with 4,6-diamidino-2-phenylindole (DAPI), and subsequently embedded in an antifade solution.
Fluorescence in situ hybridisation and image analyses were carried out using a Leica DM-RXA fluorescence microscope (Leica, Wetzlar, Germany) equipped with custom optical filters for DAPI, SA, SG and SO (Chroma Technologies, Brattleboro, VT, USA) and × 40 Plan Apo (NA 1.25) objective. Images were taken in areas of optimal cell density with minimal cellular clumps using an ORCA ER (IEEE1394 I/F) digital camera (Hamamatsu, Bridgewater, NJ, USA). Leica Q-Fluoro was used to acquire multifocus images for each of the DAPI, SA, SG and SO optical filters. Ten to 16 images were acquired and signal enumeration was performed on these digital images for 208–641 nuclei for each case. The counted signals were listed and evaluated in Excel-based customised software.
Nuclei that could not be evaluated (e.g., because of insufficient hybridisation or overlapping nuclei) were excluded from further analysis. The results for all 'countable' nuclei were registered in relocation charts in the form of patterns for the entire probe panel. For example, the pattern (2-3-3) refers to two signals for CEP7, three signals for CEP3 and three signals for TERC in a given nucleus. Nuclei with normal signal numbers for the three probes (i.e., 2-2-2) were recorded as 'diploid', and nuclei with four signals for each probe (pattern 4-4-4) were considered 'tetraploid'. The background level for the CEP7–CEP3–TERC probe panel was previously evaluated on cytological slides that contained nuclei from normal cervical cells (Heselmeyer-Haddad et al, 2003). This confirmed that deviation from the expected (2-2-2) pattern was seen in less than 2% of normal cells.
Twelve cervical adenocarcinomas (Table 1) were evaluated for copy number changes of the TERC locus at chromosomal band 3q26 using interphase FISH. The three-colour probe panel consisting of CEP7-CEP3-TERC was simultaneously hybridised to cytospin slides with interphase nuclei prepared from formalin-fixed tissue sections. All cases were successfully hybridised and analysed, whereby 208–641 nuclei per case were scored. Figure 1 shows representative hybridisations. Both normal 'diploid' patterns (2-2-2) and nuclei with nondiploid patterns were observed. The results are summarised in Table 2. In all 12 tumours, a significant proportion of 'nondiploid' nuclei was detected, and nine of the tumours exhibited >50% 'nondiploid' nuclei. In the individual tumours, nuclei with >2 TERC signals were found in similar frequencies as cells with 'nondiploid' pattern, and almost all nuclei with 'nondiploid' pattern exhibited >2 TERC signals. In the 'nondiploid' nuclei, a 'tetraploid' pattern (4-4-4) was not commonly observed. In 10 of the tumours, less than 1% of the nuclei exhibited (4-4-4) and in two cases (4-4-4) was seen in 4 and 12%, respectively (Table 2; exemplified for case 3 in Figure 2). Thus, gain of TERC was present in all tumours studied and was not an effect of 'tetraploid' status.
We observed different FISH patterns in the individual cases. For several of the tumours, one or a few predominating patterns were seen (exemplified for cases 1, 3 and 12 in Figure 2). In addition, all cases exhibited varying proportions of different but recurrent 'nondiploid' patterns. Comparison of signal numbers recorded for TERC vs CEP7 and CEP3 showed increased relative TERC copies in the 12 cases studied (range 1.04–2.0; Table 2). The absolute mean number of TERC signals per nuclei ranged between 2.3 (case 11) and 5.2 (case 10), and in five of the tumours nuclei with more than 10 signals were repeatedly encountered (Table 2). Figure 1 illustrates nuclei of case 10 with amplifications of up to 20 TERC signals and more, together with 5–6 signals for CEP3 and CEP7 (Figure 1G and H), which shows that TERC can be highly amplified in certain cases. However, the more common pattern observed in most cases are low-level copy numbers of TERC, often on a still diploid background with patterns that can be reconciled with extra chromosomes of 3 or an isochromosome 3q formation.
The clinical and follow-up information as well as HPV status of the 12 cervical adenocarcinomas are provided in Table 1. Eight cases were HPV-positive and in the other four HPV was negative. Very high proportions of 'nondiploid' nuclei with >2 TERC signals were demonstrated in HPV-positive (83–99%) as well as HPV-negative (86–99%) tumours. The absolute numbers of TERC signals per nucleus were similarly increased in HPV-positive (mean 3.4; range 2–22) and HPV-negative (mean 3.3; range 2–12) tumours. No apparent associations between TERC copy numbers and clinical characteristics, such as age at diagnosis, stage, differentiation, lymph node involvement or outcome at follow-up, were noted. Thus, gain of TERC is characteristic of cervical adenocarcinomas per se.
In our study, we analysed a series of 12 primary cervical adenocarcinomas for gain or amplification of the human telomerase gene TERC, which maps to chromosome band 3q26. Eight of the 12 carcinomas (67%) were HPV-positive (five tumours were positive for HPV 18, two for HPV 16 and one for HPV 45) (Skyldberg et al, 1999; Andersson et al, 2003a). We then used FISH with a custom-designed probe panel that includes the human telomerase gene (TERC) to assess the potential of this genetic marker to ameliorate the morphological diagnosis of cervical adenocarcinomas. This is the first study that reports the consistent gain of the human telomerase gene TERC in cervical adenocarcinomas.
Yang et al (2001) analysed 20 cases of cervical adenocarcinomas with CGH and found that genetic alterations were evident in most of the cervical adenocarcinomas, including the gain of 3q, which was detected in 70% of these 20 tumours. From the findings of similar 3q amplifications in adenocarcinomas as reported for squamous cell carcinoma, it was proposed that similar mechanisms are involved in the development of the two types of cervical cancer (Yang et al, 2001). In our study, using FISH we detected a gain of 3q in all our cases. This difference is likely attributable to the different sensitivity of the respective techniques. Detection of a trisomy by CGH requires this numerical aberration to be present in at least 40% of the cells. Fluorescence in situ hybridisation, of course, detects changes on a single-cell basis and is therefore not sensitive to dilution. Additionally, small regional low-copy number amplicons might escape detection by CGH.
In our study, HPV infection was not detected in four of the cases, which could either reflect true HPV negativity or represent 'false negatives' owing to technical difficulties in HPV genome detection. In the current literature, HPV infection has not been reported in the same proportion in adenocarcinomas as in squamous cervical carcinomas (Tenti et al, 1996; Skyldberg et al, 1999; Andersson et al, 2003b; Clifford et al, 2003; Zielinski et al, 2004; Castellsague et al, 2006). Perhaps, oncogenic factors other than HPV are more likely to play a role in the malignant transformation of cervical adenocarcinomas (Skyldberg et al, 1999; Pirog et al, 2000).
The application of screening programmes has reduced the incidence of squamous carcinoma in Sweden substantially during the last decades (Mählck et al, 1994; Ponten et al, 1995). Yet, several studies suggest that a single Pap smear has a high false-negative rate (Macgregor et al, 1994). A review of evidence-based data revealed that as many as 50% of precancerous cervical lesions may be missed by a single Pap test (Sherman et al, 1994). Kinney et al (1998) showed that only 30% of women with histopathologically confirmed high-grade disease had corresponding atypia in their Pap smears. Against this background, a new screening strategy for cervical cancer has been presented in which HPV testing is combined with cytological examinations (Walboomers et al, 1999). However, screening methods currently utilised to detect preinvasive and early invasive squamous cervical cancer had only a limited effect in detecting precursor lesions of cervical adenocarcinoma.
Hildesheim et al (1999) classified women as having rapid-onset cervical cancer with the following criteria: a detection of cervical cancer within 5 years of at least one normal Pap smear or within 10 years after the first sexual intercourse. Our data showing that 10 of the 12 women had a normal Pap smear within 3 years before the diagnosis of invasive disease may support the hypothesis of a rapid-onset carcinoma. On the other hand, as the sensitivity of a Pap smear for the detection of cervical adenocarcinomas is very low (Krane et al, 2001), the rapid-onset hypothesis may not apply to our cases.
Cervical squamous cell carcinomas are defined by a nonrandom and recurrent distribution of genomic imbalances. In addition to HPV, the sequential transformation of cervical squamous epithelium requires the acquisition of additional copies of chromosome arm 3q. In the current study, we wanted to analyse and understand whether the gain of 3q plays a similar role in the tumorigenesis of cervical adenocarcinomas. Using a genomic probe for the TERC gene on chromosome band 3q26 in combination with two centromere-specific probes (CEP3 and CEP7), we showed high copy numbers of this locus in cervical adenocarcinomas. Gain or amplification of 3q was found in all cervical adenocarcinomas investigated. Therefore, the application of this probe set may provide an objective genetic test for the diagnosis of cervical adenocarcinomas and might assist in the interpretation of smears with a high degree of glandular cells.
Heselmeyer-Haddad et al (2003) showed in a series of Pap smears of cervical precursor lesions of squamous cell origin that analysis of the TERC gene amplification is able to distinguish normal epithelium and low-grade dysplasia from the group of high-grade lesions with high specificity and sensitivity. In another paper, the same group showed that gain of TERC was found in 33% of cytological normal Pap smears from women who developed carcinoma in situ or invasive cervical squamous cancer in the future (Heselmeyer-Haddad et al, 2005). In the same paper, the authors were also able to show that all CIN1/CIN2 lesions with a diploid pattern for the TERC probe panel (CEP7–CEP3–TERC) eventually regressed to normal Pap smears, whereas the CIN1/CIN2 lesions with TERC amplification progressed. Lesions with a tetraploid pattern for the panel (four signals for each probe) could develop either way. The author concluded that the detection of gain and amplification of TERC in routinely collected Pap smears can assist in identifying lesions with a high progression risk. As the results of the current study indicate, TERC appears to play a similar important role in the carcinogenesis of cervical adenocarcinomas. Interestingly, even the patterns of gain found in the adenocarcinomas are very comparable to the patterns found in cervical dysplasias of squamous cell type (Heselmeyer-Haddad et al, 2003, 2005). The most common patterns observed for both of the cell types are low-level gains of TERC on a diploid background (3–5 signals of TERC). Given the similarity to the results of the studies of TERC in cervical squamous cell lesions, it seems to be a distinct possibility that analysis of TERC gain may also help to find women at risk for developing adenocarcinoma. An objective molecular marker in this patient group is of extreme importance because of the cytomorphologically difficult identification of these cells and the limited numbers of representative cells owing to technical problems in sampling these lesions. As shown in our study, many women with cervical adenocarcinoma presented with morphologically normal Pap smears, often only 1–2 years before diagnosis. A marker like TERC could have considerable impact on the detection of cervical adenocarcinomas at an earlier stage. Fluorescence in situ hybridisation analyses of precursor lesions, that is, adenocarcinomas in situ and dysplasias will be the next step to verify the potential of TERC as a marker of early detection and progression in cervical adenocarcinomas. We are therefore planning to conduct both retrospective studies with archival Pap smears and prospective randomised studies with routinely collected Pap smears.
We wish to express our gratitude to Buddy Chen and Joseph Cheng for IT support and manuscript editing, and Juan Castro, Inga Maurin, Nicole White and Diana Tong for excellent technical assistance. This study was supported by the Swedish Cancer Foundation, Swedish Research Council, Medical Research Council, Göran Gustafsson Foundation, Cancer Society in Stockholm, Stockholm County Council, NIH and Swedish Labour Market Insurance.
PubMed Central Canada is a service of the Canadian Institutes of Health Research (CIHR) working in partnership with the National Research Council's national science library in cooperation with the National Center for Biotechnology Information at the U.S. National Library of Medicine(NCBI/NLM). It includes content provided to the PubMed Central International archive by participating publishers.


text:
This Men's Wallet With Coin Bag Zipper is an accessory that every man needs. It is portable and easy to carry around with all your daily essentials like credit cards, cash, gift cards, change and other important cards. This leather wallet has a neutral color that will match any outfit by adding a little edge and style. This will also make a great gift for any every stylish man you know!
Product Description
Color:Coffee,Black, Blue
Material:First-class PU


text:
This Is How Popular Tahidi High Actor Spent His Last Moments Before His Sorrowful Death
Barely a few months after the nation lost one of celebrated actors Mzee Ojwang', the entertainment industry has lost another talented actor, Kevin Rost. The deceased succumbed to death following an asthma attack. Kevin's death comes four days after the burial of his aunt. Until his death, Kevin was an actor in Tahidi high, a school drama series that reflects what goes on in our schools.
Despite being an orphan, Kevin had big dreams to accomplish in life. Thousands of Kenyans from social media, the political arena and the entertainment industry have joined his family in mourning his sudden death. This is not only a big loss to the entertainment industry but to the whole nation considering the fact that many Kenyans are making a living out of acting. As we wait for his burial, we also join others in praying for his family to stand strong during this moment of trial. Rest in peace Kevin, We loved you but the Almighty God loved you most.
Leave us a comment on Facebook and Share


text:
It might sound a bit racist but I thought Black guys didn't like to swim?I guess if it's a dip in a deep and wet Japanese pool- no stereotypes remain. This release was very nice: a bomb ass Japanese babe with bouncy T&A and some very beefy Black studs to give her a ride. Serious beefcakes only here- no fatties.Format: mp4Duration: 2:24:19Video: 640x480, AVC(H.264), 635kbpsAudio: 62kbps
Sayuri Kobayashi - tutor
Tsuyoshi & Haruki & Mitsuru
Gachinco 457 - Haruki


text:
The Bar Council of India (BCI) has finally uploaded on its website the much awaited list of the de-recognised law colleges across India.
Speaking to Bar & Bench, Rahul Singh Member Directorate of Legal Education said, "For the first time after a gap of so many years the BCI has been so pro-active. Under the leadership of Mr. Subramanium a lot of positive changes are being implemented, which is obvious. Mr. Subramanium being an ex-officio member has been able to initiate
Related Articles
Get the latest legal jobs delivered to your inbox!
Sign up and receive the latest updates on legal openings across the country!


text:
White Banners (1938)
Plot Summary
A homeless woman named Hannah drifts into the lives of the kindly Ward family, in a small Indiana town in 1919. Hannah makes herself useful as a cook and housekeeper and stays with the Wards... but her real interest is in meeting their neighbor, teenager Peter Trimble. It turns out that Peter is the son she bore out of wedlock and gave up for adoption, and now Hannah has returned to town to see what sort of young man her son has become.- Written by Dan Navarro <firstname.lastname@example.com>
Be the first to contribute! Just click the "Edit page" button at the bottom of the page or learn more in the Synopsis submission guide.


text:
WPEasyEmail – Mailjet (Miscellaneous) Free Nulled
WPEasyEmail – Mailjet makes it easy to send emails with Mailjet on your WordPress site. This means you don't need a mail / SMTP server to send emails. It works automatically in the background, all you need to do is enter your Mailjet API key and turn it on! Fully documentation and guides are available too so what are you waiting for, stop worrying about email and start using WPEasyEmail – Mailjet.
We want you to have a great time with WPEasyEmail – Mailjet so we've made sure its easy to use. We've also created a great documentation website that you can search for whatever you need to do, it also has great quick start guides. If anything does go wrong we want you to know that our support team will be there to support you with quick, friendly and helpful support.
You won't believe how good our support is so we've included our statistics for 2014 below:
= 1.1.0 - 4th August 2016 = * Fixed some output in sending * Added change log = 1.0.0 - 18th June 2016 = * Initial release
|Last Update
|5 August 16
|30 March 16
|Compatible With
|WooCommerce 2.6.x, WooCommerce 2.5, WooCommerce 2.4.x, WooCommerce 2.3.x, WooCommerce 2.2.x
|Files Included
|JavaScript JS, HTML, CSS, PHP
|Software Version
|WordPress 4.6, WordPress 4.5.x, WordPress 4.5.2, WordPress 4.5.1, WordPress 4.5, WordPress 4.4.2, WordPress 4.4.1, WordPress 4.4, WordPress 4.3.1, WordPress 4.3, WordPress 4.2, WordPress 4.1, WordPress 4.0
WPEasyEmail – Mailjet (Miscellaneous) Nulled Free
WPEasyEmail – Mailjet (Miscellaneous) Download
WPEasyEmail – Mailjet (Miscellaneous) zip
WPEasyEmail – Mailjet (Miscellaneous) Demo
Be the First to Comment!


text:
Mistah Jolson: As Told to Alban Emley.
JOLSON, Harry
Place Published: Hollywood
Publisher: House-Warven
Date Published: 1952
Description: Illustrated. 257 pages, 8vo, burgundy cloth, d.w. Hollywood: House-Warven, (1952). Second Edition. A fine copy in a near fine dust wrapper.Edition: Second
Jacket: Y
Binding: hardcover
Condition: near fine
Language: English
Type: Books
Book ID: 225230
By This Author: JOLSON, Harry
By This Publisher: House-Warven


text:
iPhone apps
Consolation by Michael Redhill
ConsolationMichael RedhillLittle, Brown and CompanyJanuary 10, 2007From the award-winning author of "Martin Sloane" and "Fidelity" comes a riveting story of two families in different centuries--one searching for the past, the….. Read more
iPhone Screenshots
Video Reviews
No video review..
Customer reviews
Be the first to review this app. Write a Review
Be the first question this app.
Users Community
The information may be outdated. For actual information go to iTunes
Related to «Consolation by Michael Redhill» applications
Henry's Parade by Traci N. Todd; illustrated…
Henry's Parade Traci N. Todd; illustrated by Michael GarlandKindermusik International, Inc.2003Henry's happy song begins with only a little whistle. But soon a group of panpipe players, Mrs.… [more..]
Price: $0.99 |
The Baker Street Letters by Michael Robertson
The Baker Street LettersMichael RobertsonMinotaur BooksJune 23, 2009First in a spectacular new series about two brother lawyers who lease offices on London's Baker Street--and begin receiving mail… [more..]
Price: $13.99 |
The E-Myth Attorney (by Michael E. Gerber et al.)
THE E-MYTH ATTORNEY by Michael E. Gerber et al. (unabridged) is presented by Blackstone Audio and comes with what is perhaps the best audiobook app available (see FEATURES, below)."Gerber's powerful… [more..]
Price: $9.99 |
Ubuntu Certified Professional Study Guide (Exam…
Ubuntu Certified Professional Study Guide (Exam LPI 199)Michael JangMcGraw-Hill Osborne MediaJuly 7 2008The Best Fully Integrated Study System Available for Exam LPI 199 With hundreds of practice… [more..]
Price: $49.99 |
Ubuntu Server Administration by Michael Jang
Ubuntu Server AdministrationMichael JangMcGraw-Hill Osborne MediaNovember 17, 2008Administer Ubuntu Server in the Enterprise Realize a dynamic, stable, and secure Ubuntu Server environment with… [more..]
Price: $49.99 |
Handbook of Optics, Third Edition Volume I :…
Handbook of Optics, Third Edition Volume I : Geometrical and Physical Optics, Polarized Light, Components and Instruments(set)Michael BassMcGraw-Hill ProfessionalSeptember 22, 2009The most… [more..]
Price: $149.99 |
The Reaper - A Revised Version by Michael Aye
The Reaper - A Revised Versionby Michael AyeCaptain Gilbert Anthony has a lot on his mind. He has just been decorated for extraordinary bravery under fire, been given command of the fourth-rate… [more..]
Price: $4.99 |
Waking Caliban by Michael Cale
Waking Caliban by Michael CaleA 400 year-old puzzle, a modern-day hunt to the death.The world's greatest-ever literary figure died, leaving no public record of his life apart from a few scant notes… [more..]
Price: $4.99 |
Barracuda by Michael Aye
Barracudaby Michael AyeAdmiral Lord Gilbert Anthony and his brother Lieutenant Gabriel Anthony, fighting for the Crown during the American Revolution, find adventure, daring privateers, and a ghost… [more..]
Price: $4.99 |
Blade Runners, Deer Hunters and Blowing the Bloody…
Blade Runners, Deer Hunters and Blowing the Bloody Doors Off: My Life in Cult MoviesMichael DeeleyPegasusApril 1, 2009A rollercoaster ride of a Hollywood memoir, by the producer of Blade Runner, The… [more..]
Price: $14.99 |


text:
Celtic v Motherwell
Today 3pm
Last season: Celtic 1 Motherwell 0, Motherwell 1 Celtic 1, Celtic 2 Motherwell 1
Last five league matches: Celtic WLWWL; Motherwell WLDLW
Top scorers: Scott McDonald (Celtic) 8; Ross McCormack and Chris Porter (Motherwell) 5
Match odds: Home 2-9; Away 9-1; Draw 19-5
Referee: S Dougal.
Gretna v Inverness CT
Today 3pm
Last season: No corresponding fixtures last season
Last five league matches: Gretna LWLLL; Inverness CT LWWDL
Top scorers: Fabian Yantorno (Gretna) 3; Dennis Wyness (Inverness CT) 6
Match odds: Home 2-1; Away 11-10; Draw 11-5
Referee: M McCurry.
Hibernian v St Mirren


text: Hey Dr. Bob! Here i am again, blowing my own trumpet! "Six awards in Sept for Changi Airport CHANGI Airport is giving its competition a run for the money: It has bagged six awards given out by aviation organisations and industry magazines so far this month. . . . These include being named best airport in the world for the 13th straight year by readers of the Asia-Pacific edition of Business Traveller magazine. The same group also voted it as having the best duty-free shopping. . . . Readers of Travel Savvy, which is circulated mainly in the United States and in Britain, picked it as the best in the world, as did those surveyed by the British edition of Conde Nast Traveller, which has a circulation of about 83,000. The magazine's rankings are recognised worldwide as a benchmark for the travel industry. In a website posting, editors of Conde Nast Traveller said: 'If your flight is going to be late, you would rather be delayed at Singapore's Changi Airport...'" The Straits TImes Travel Savvy Magazine Best of Awards


text:
Get Best pregnancy pillow for complete comfort
All we know that pregnancy is a thing that most of women find trouble in managing with. As of this, different solutions occur to be formed for creating this a far more manageable experience. Such thing might be the good quality pregnancy pillow. It provides different positive benefits that expectant female will observably love. Some of these are mentioned here in this article:
It provides support and comfort.
The very first and the very important aspects to using these kinds of pillows might be the ease and comfort it offers. Basically, standard pillows do not have the design and style to guide expectant female. Doing work with one point out sleeping only is not as comfortable as it actually should be. Because, it is feasible to foresee, not enough rest can have a bang on both new baby and mother.
If talking about benefits of pregnancy pillow then it turns into a health advantage simultaneously. Mainly, expectant women can tot up on support on their abdomen and lower back. These extraordinary pillows are formed to be used where they are most required. They might be situated everyplace and their type makes it feasible for complete support in most possible places.
These pregnancy pillows are easily available in different shapes that assist them to obtain the work done in a perfect manner. Any combination might be used for utmost support and comfort. The pillow with C-shape is amazing at sizing natural curves of a woman to assurance a comfortable sleep. Some other pillows might be used to complete support the abdomen, lower side, neck and head at accurately the same time.
Apart from ease, these pillows are produced to make happy one more momentous function. These are formed to help cure pain related with pregnancy. The complete support they offer, they are in a perfect position to relieve the pain on relation of arthritis on the lower back, neck, spine with legs. Apart from this, they also can keep away from it altogether.


text:
Is Medical Direct incorrect or missing key business information? Update your Hotfrog listing today.
Contact details
Are these details correct?
Hotfrog Ireland provides information regarding Medical Direct. Medical Direct provides herbs services. Contact them on +353 (0)66 9761066 or by visiting them on their website http://www.medicaldirect.ie.
Is Medical Direct your business? Claim your listing and attract more leads by adding more content, photos and other business details.
We have more herbs services available on Hotfrog Ireland. You can update your search for herbs by location, keyword or service options.
Small Business Hub
Sharing tips, ideas and advice to help grow your small business.
Create your free Hotfrog business profile
Follow Hotfrog on:
Share on:
Hotfrog Small Business Hub


text:
Dr. Charles Day DMD
- General Dentistry Gadsden, AL
Patient Reviews
Reviews reflect patients' level of satisfaction with the care they received from this provider. Dr. Charles Day xhas an overall rating of 5.0.
Dr. Charles Day, DMD is a Dentist primarily located in Gadsden, AL. His specialties include General Dentistry. He speaks English.
Find out the languages this doctor/ or staff may speak.
View all
Specialties & Expertise
Dr. Charles Day has the following 9 areas of expertise and 1 specialty.
See areas of expertise for treating specific conditions, procedures and surgeries for this doctor.
View all
Health Guides
more health guides
Locations & Directions
Nearby Dentists
Dr. Charles Day, DMD is similar to these 3 Dentists near Gadsden, AL.
Dr. John Hawkins
Dr. George Stacey Jr
Dr. Rex Wilson