text:
Is Rehman Clinic incorrect or missing key business information? Update your Hotfrog listing today.
Contact details
Are these details correct?
Hotfrog SouthAfrica provides information regarding Rehman Clinic in Johannessburg. Rehman Clinic is located at 3rd Avenue Mayfair, Johannessburg and provides Medicine services. Contact them on +27 11 837 8932 or by visiting them on their website http://www.rehmanclinic.co.za.
Is Rehman Clinic in 3rd Avenue Mayfair, Johannessburg your business? Claim your listing and attract more leads by adding more content, photos and other business details.
We have more Medicine services in Johannessburg available on Hotfrog SouthAfrica. You can update your search for Johannessburg Medicine by location, keyword or service options.
Small Business Hub
Sharing tips, ideas and advice to help grow your small business.
Your profile without ads
Have you considered upgrading to Hotfrog AdVantage? No competitor advertising means exclusive focus on your business. You take centre stage.
Create your free Hotfrog business profile
Follow Hotfrog on:
Share on:
Hotfrog Small Business Hub


text:
By Eddie Timanus, USA TODAY
Two of the three leaders in the race for the league's Bowl Championship Series berth square off as No. 19 Pittsburgh steams down the Ohio River to take on No. 20 Cincinnati. With only Syracuse remaining on their Big East dance card and having beaten West Virginia, the Bearcats can all but lock up the big-money bid. But UC has not beaten Pitt in seven tries. The Panthers, coming off a bye, embark on a challenging three-game stretch that would give them the outright conference title if they run the table. Cincinnati's offense continues to thrive despite — or perhaps because of — numerous QBs seeing action. Tony Pike (bruised sternum) is probable this week, but the depth is better than it has been for most of the season with Dustin Grutza back from a leg injury. The passer hasn't mattered to WRs Mardy Gilyard and Dominick Goodman, who each have eight TD catches and have combined for 1,610 receiving yards. Pitt LB Scott McKillop is accustomed to being everywhere at once, but he'll need backing from FS Eric Thatcher to keep UC's big gains to a minimum. The Panthers' 1,000-yard TB, LeSean McCoy, must make his presence felt quickly. If he can't, Pitt QB Bill Stull will have to take his chances against the Bearcats' dangerous CBs, Mike Mickens and DeAngelo Smith. Hot PK Conor Lee might give Pitt the edge in a close game.
West Virginia will try to keep pace with a victory at Louisville, which is trying to avert a sub-.500 finish. The Mountaineers are still a run-first offense with QB Pat White and TB Noel Devine capable of breaking loose any time, but finding aerial balance has been difficult. WR Jock Sanders might have more success this week against a Cardinals secondary that allows the most passing yards in the conference. The loss of CB Woodny Turenne (broken collarbone) won't help. The Cardinals have enough offensive weapons to keep pace if QB Hunter Cantwell takes care of the ball. He'll need help from WR Doug Beaumont and TB Victor Anderson, who will try to stay clear of Mountaineers LB Mortty Ivy.
Two bowl-eligible teams round out the weekend Sunday as Connecticut visits South Florida, though the Bulls almost certainly need another victory to receive an invitation. USF looks to end a three-game skid caused primarily by a slew of turnovers. Bulls QB Matt Grothe can be a dynamic playmaker outside the pocket, but his gambling style isn't a good mix with the Huskies' ballhawking defense featuring rush DE Cody Brown and CB Robert McClain. If Grothe can stay in rhythm, WRs Taurus Johnson and Jessie Hester will benefit. UConn QB Tyler Lorenzen made an early return from a foot injury at Syracuse, though his main job will still be feeding the ball to TB Donald Brown, the nation's leading rusher. He can expect to see a lot of Bulls LB Tyrone McKenzie.
Atlantic Coast
No. 23 Maryland is alone atop the league's Atlantic Division. But neither of the Terrapins' last two league opponents will give up the division fight easily. Up first is Saturday's prime-time visit from Florida State, which closes out its conference schedule needing a couple of breaks to win the division. Given Maryland's propensity this season to beat Top 25 teams but lose to unranked opponents, coach Ralph Friedgen might want to show his players last week's polls. For that curious Terps trend to continue, the Seminoles will need a steadier performance from QB Christian Ponder and more touches for WRs Greg Carr and Preston Parker. Maryland doesn't generate many takeaways but relies on LBs Alex Wujciak and Dave Philistin to get off the field with third-down stops. Terps TB Da'Rel Scott is on pace to eclipse the 1,000-yard mark, but he'll need aerial cover from QB Chris Turner and WR Darrius Heyward-Bey to make headway. They'll have to contend with DE Everette Brown and CB Patrick Robinson.
No. 25 Boston College, which hosts Maryland next week, also has its own Atlantic fate in its hands. But the Eagles first must survive Saturday's trip to Wake Forest, whose hopes to play for the conference title are alive despite last week's setback at North Carolina State. The Demon Deacons need this win and two Maryland losses. Wake QB Riley Skinner continues to lead the ACC in total offense, though his lack of ground support and the ongoing absence of PK Sam Swank (quadriceps) has cut into the point production. Eagles LB Mark Herzlich will likely keep the clamps on the running game, so some deep passes to WR D.J. Boldin will be needed. The Deacons have a hard time when they don't win the turnover battle. BC QB Chris Crane has cut down his miscues, but he must remain vigilant with Wake CB Alphonso Smith and LB Aaron Curry on patrol. If TB Montel Harris can get rolling, the Eagles should be in good shape.
Big Ten
The league wraps up its 2008 slate this weekend with No. 8 Penn State attempting to lock up its place in the Rose Bowl at home against No. 15 Michigan State. The Spartans will claim a piece of the conference title with a victory but will need Michigan to upend No. 10 Ohio State to make it to Pasadena. The marquee matchup pits two of the league's top three rushers. Spartans TB Javon Ringer is a workhorse, averaging more than 31 carries and 141 yards a game. MSU's bye week should help him enter the game fresh, but he'll still need some production from QB Brian Hoyer to keep Nittany Lions LB Navorro Bowman from crowding the line of scrimmage. Penn State TB Evan Royster is also good for more than 100 yards per outing on the ground. WRs Jordan Norwood and Deon Butler stretch the field to give him room, but QB Daryll Clark must make use of them. He'll have to watch out for Spartans SS Otis Wiley while doing so.
Minnesota's turnaround season has lost some of its luster thanks to a three-game slide. But the Golden Gophers can head into the postseason on a high note if they can reclaim the prize pig known as Floyd of Rosedale from visiting Iowa. The Hawkeyes go for a sweep of their trophy games, having beaten Iowa State and Wisconsin. Minnesota's slump coincides with top WR Eric Decker's ankle injury. He will play this week, which should help QB Adam Weber's confidence and give TB DeLeon Eskridge room to operate. They must all beware of Iowa LB Pat Angerer and DT Mitch King. Hawkeyes TB Shonn Greene, first in the Big Ten and second nationally in rushing, will get plenty of attention from Gophers LB Lee Campbell. He would appreciate any help QB Ricky Stanzi and WR Andy Brodell can provide.
Big 12
The winner of this week's game of the century featuring No. 2 Texas Tech at No. 5 Oklahoma won't quite be guaranteed a spot in the BCS title game but will certainly be in the discussion the final two weeks of the season. The Red Raiders will lock up the Big 12 South and a date with Missouri in the conference final with a victory. The Sooners must beat Tech and archrival Oklahoma State next week and hope for a favorable BCS ranking to prevail in the three-way tie. But all that aside, this meeting of the first- and third-highest scoring teams in the country should be just plain fun. The showdown between QBs Graham Harrell and Sam Bradford that could determine the Heisman Trophy winner is the top story line. Harrell and the Red Raiders have the nation's second-most productive offense. Much of the credit goes to Tech's rock-solid offensive line, anchored by G Rylan Reed, that has allowed only five sacks despite regularly attempting 45-50 passes a game. The blockers are even opening holes for TBs Baron Batch and Shannon Woods, but WRs Michael Crabtree and Detron Lewis are still the primary movers. Harrell's third aerial option, diminutive WR Eric Morris, might be the most difficult matchup for the Sooners' defense, which has struggled since losing LB Ryan Reynolds to a season-ending knee injury in the Texas loss and will be without DE Auston English (sprained knee) this week. The good news for Oklahoma is Bradford has a high-octane attack of his own that leads the nation in scoring. His favorite targets recently have been WRs Juaquin Iglesias and Ryan Broyles, who will challenge Raiders CBs Darcel McBath and Daniel Charbonnet. TE Jermaine Gresham provides Bradford an excellent inside option, but the Sooners' best approach might be using TBs DeMarco Murray and Chris Brown to control the clock.
Two hurdles remain for No. 21 Oregon State in its quest for a Rose Bowl bid. The test this week is at bowl-bound Arizona, which is hoping to move up in the Pac-10 pecking order. With the Rodgers brothers, WR James and TB Jacquizz, doing most of the damage for the Beavers, it's easy to forget that QB Lyle Moevao also has speedy WR Sammie Stroughter in his arsenal. All that figures to be bad news for an Arizona defense that was torched for 55 points by Oregon last week, but the return of LB Sterling Lewis from a sprained ankle could help. Wildcats QB Willie Tuitama is getting good production from WR Michael Thomas and support from TBs Nic Grigsby and Keola Antolin. But his most effective weapon might be TE Rob Gronkowski, who will try to occupy Oregon State safeties Greg Laybourn and Al Afalava.
Stanford has one last chance to get to six victories and bowl eligibility. The Cardinal make the short trip to Berkeley for this year's version of the Big Game with arch nemesis California. Stanford TBs Toby Gerhart and Anthony Kimble have combined for more than 1,700 rushing yards despite getting only limited aerial coverage from QB Tavita Pritchard. Golden Bears LBs Michael Mohamed and Anthony Felder will try to keep them bottled up. Cal's QB play has been just as spotty down the stretch, with neither Kevin Riley nor Nate Longshore able to assemble a complete game. Riley will start this week, and he will want to get TB Jahvid Best as many touches as possible.
With the division winners already determined and Alabama and Florida almost certainly BCS-bound, the rest of the conference is competing to move up the bowl ladder. Most important this weekend is No. 18 LSU's home date with Mississippi, with a possible New Year's Day bowl at stake. This rivalry, more than a century old, will be dubbed the Magnolia Bowl with an accompanying trophy for the first time. LSU QB Jarrett Lee has 14 TD passes and 15 interceptions, seven of which have been brought back for scores. But the Tigers need him to keep throwing to take full advantage of a talented receiving corps, featuring Brandon LaFell and Demetrius Byrd, and create space for TB Charles Scott. Nevertheless, Ole Miss FS Kendrick Lewis will be waiting for any stray tosses caused by backfield penetration by DT Peria Jerry. The Rebels' offense isn't flashy, and QB Jevan Snead can also be interception-prone when pressured. But WR Shay Hodge is a good primary target and TB Cordera Eason leads a deep backfield. Speed rushes from Tigers DEs Rahim Alem and Tyson Jackson could keep Ole Miss grounded.
Conference USA
Houston has control of the West after scoring 70 points against Tulsa. But a couple of roadblocks remain. Up next is a visit from Texas-El Paso, which needs a win to become bowl-eligible and has a powerful offense of its own. Houston QB Case Keenum has 3,794 passing yards and 35 TDs with only nine interceptions. He has overcome the loss of top WR Patrick Edwards (broken leg) in part because of a breakout performance from WR/KR Tyron Carrier. The Miners will counter with QB Trevor Vittatoe, who has thrown for three scores in each of his last seven games. WRs Chris Adams and Jeff Moturi are his top targets, and PK Jose Martinez has hit his last 15 field goal attempts. The defenses might be overshadowed somewhat, but Cougars CB Loyce Means and UTEP LB Adam Vincent could be momentum changers.
Notre Dame staved off a near catastrophe against Navy to become bowl-eligible. The Fighting Irish will assure themselves of a winning record if they take care of business against Syracuse, which is playing out the string for outgoing coach Greg Robinson. Fighting Irish QB Jimmy Clausen could use a quick start after failing to throw a TD pass in his last two outings. WR Michael Floyd (knee) won't be available, but WR Golden Tate and TB Armando Allen should take up the slack. Little has worked for the Orange passing game with QB Cameron Dantley or Andrew Robinson at the helm. TB Curtis Brinkley has been a bright spot for the offense, but he's sure to get attention from Notre Dame LB Maurice Crum.
Buffalo is a win away from clinching the MAC East for a shot at its first conference title in program history. The Bulls will try to get it tonight at Bowling Green, which also can win the division on its own with victories in its last two games. Buffalo has won its share of tight games this season, including the four-overtime marathon at Akron. TB James Starks, QB Drew Willie and WR Naaman Roosevelt pace an attack that is scoring better than 30 points a game. The Falcons will counter with QB Tyler Sheehan, who hopes to regain the services of top RB Anthony Turner (shoulder). Bulls LB Justin Winters leads a group that has recovered 16 fumbles this season. Falcons DE Diyral Briggs has seven sacks, all solo.
Mountain West
There are two games of note as Air Force goes for a major upset at No. 17 TCU. But most eyes will be on No. 14 Brigham Young at No. 7 and undefeated Utah, where a BCS-busting conference title is on the line. The Utes will assure themselves of a major bowl slot with a victory. The Cougars can put themselves in the mix, though they'd likely need help in the form of a Boise State loss. Both offenses are rounding into shape for the big showdown. The Utes' outing against last-place San Diego State a week ago might be less noteworthy than the Cougars' numbers against Air Force. Nevertheless, Utah QB Brian Johnson has delivered when needed all season. WR Freddie Brown is the most frequent catcher, but Brent Casteel and Bradon Godfrey must also be accounted for by LB David Nixon and the BYU back eight. Cougars QB Max Hall is getting an all-timer of a season from WR Austin Collie at a school known for throwing the ball. TE Dennis Pitta is also a key contributor. He is listed as questionable with a sprained knee but will almost certainly play in the rivalry game if possible. The Utes' best chance to slow the BYU attack could come from DEs Paul Kruger and Koa Misi. With all the aerial weapons, the game might come down to whether Utah TB Matt Asiata or Cougars TB Harvey Unga can provide more tough yards.
Sun Belt
Louisiana-Lafayette, despite coming up short at Florida Atlantic a week ago, can still earn the SBC title and New Orleans Bowl spot by winning its final two games. First up Saturday is a trip to conference co-leader Troy. The Trojans, who also can win the outright title with two more victories, must rebound from last week's collapse at LSU. The Ragin' Cajuns must get their two-pronged running game, featuring TB Tyrell Fenroy and QB Michael Desormeaux, moving much earlier. WR Jason Chery provides an aerial threat, but the offense isn't built for a comeback. Trojans QB Levi Brown has done an efficient job since taking over for injured Jamie Hampton five games ago. WR Jerrel Jernigan and TB DuJuan Harris are the main ball-handlers. Troy LB Boris Lee and Cajuns LB Daylon McCoy will be in on many stops.
Western Athletic
No. 9 Boise State can remove all the suspense from the final weekend of the WAC season with a victory Saturday at Nevada. The Wolf Pack will need help to catch the Broncos in the final standings but have a chance to pick up a program-defining win. Regular WAC followers will recall that these squads battled through four overtimes a year ago on Boise's blue turf before the Broncos prevailed by a basketball-like 69-67. That game was the first career start for Nevada QB Colin Kaepernick, the WAC leader in total offense this season. He and TB Vai Taua each have topped 1,000 rushing yards from the "pistol" formation that has become the Wolf Pack's trademark. FS Jeron Johnson, the Broncos' leading hitter who occasionally runs afoul of the rules, must play with discipline. Boise State QB Kellen Moore has a 71.2% completion rate with 20 TDs and six interceptions. He received the best ground support of the season last week from TBs Ian Johnson and Jeremy Avery, but he can always go back to WR Jeremy Childs if Nevada LB Joshua Mauga and Co. sell out too much to stop the run.
Weekend TV games
Times p.m. Eastern. Lines by USA TODAY sports analyst Danny Sheridan. Jeff Sagarin's power ratings show the relative strength of teams; 2.92 points added to the home team's rating to calculate the difference.
Guidelines: You share in the USA TODAY community, so please keep your comments smart and civil. Don't attack other readers personally, and keep your language decent. Use the "Report Abuse" button to make a difference. Read more.

subset: commoncrawl


text:
- Brain-melting arcade-puzzle-platformer.
- Play as the fluffy, slug-goatish creature, illi.
- Travel through a beautiful, surrealistic universe.
- Take on 60 gravity defying levels!
- Over 170 quests to be completed.
From us at Set Snail, we hope you enjoy the game.
DeveloperSet Snail
Last UpdateMay 24, 2016
Update notes
We hear you! The energy system has been removed, play all you want :) Now you just see ads once in a while instead, also, you awesome people who bought infinite energy, you still won't see ads. Thank you for your support.
The UI has been optimized in various places.
Collect Light Crystal and Help illi Save Barren Worlds
The world as you know it will forever be altered once you play the mind-bending puzzle game illi. More than just another puzzle game, you are tasked with helping the adorable creature illi as he explores a variety of barren lands in his world. With each step through the portal, the gravity and physics you know will change, making every land a new challenge to overcome. Fear not, my friends, for the magical illi can bend the very fabric of time to his will. Along your way, collect light crystals that have been left over from a time long forgotten.
The game illi is much like the sluggish creature illi. They are both amazingly adorable, love a good time, and are both oh-so-fluffy! Take on more than fifty crazy levels and complete over 170 different quests as you and illi ride the mystical waves on your PC or Mac.
Now You Can Become a Twitch Broadcaster
The world of Twitch broadcasting is exciting and glamorous. Okay, maybe not glamorous, but it is a heck of a lot of fun. Play your favorite Android-powered video games and apps and broadcast each exciting moment to millions of players all over the globe. No more do players require a slew of extra equipment and cables to9 mirror your screen and broadcast it to the world. Now, you only need the free BlueStacks 2 player and you can use the ease of one-click controls to stream every single game to the massive twitch.tv network. meet other illi players, swap gaming tips, and even start building your own following of fans nd followers.


text:
Greetings Guest!!Dismiss Notice
In order to combat SPAM on the forums, all users are required to have a minimum of 2 posts before they can submit links in any post or thread.
House Search ............ pretty please with sugar and honey!!
Discussion in 'UHall' started by Parnoc, Aug 2, 2014.


text:
Please don't ***** about your boss to me when you know she is my best friend. Idiot. Good luck keeping your job now.
Please don't ***** about your boss to me when you know she is my best friend. Idiot. Good luck keeping your job now.
dancingchipmunk (08-04-2013)
I am so angry...it just gets worse
Sent from my GT-I9100 using BubHub
Dude ... Did you actually bathe in your cologne?? - I'm getting an instant headache sitting next to you in the waiting area :/
Tried breathing through my mouth instead and now I can taste it!!!
Boobs... Please stop growing. I feel like your about to explode out of my top!
Because I freaking said so!
dancingchipmunk (09-04-2013),mrsoptomistic (09-04-2013)
So tired i got appointment time wrong. Now i have wait a hour (that if they are running on time) with 5 kids 2 that are sick but 1 has 40 temp.
F**K Centrelink right in the A!
Last edited by White Mage; 09-04-2013 at 11:38. Reason: Spelling mistake.. lol
cluckcluck (09-04-2013)
So sick gahhh
Phone companies that continuously try and screw me over.
Pregnant for the first-time?
Not sure where to start? We can help!
Our Insider Programs for pregnancy first-timers will lead you step-by-step through the 14 Pregnancy Must Dos!


text:
Latest Updates
Casino Bookies point is a websites dedicated to all casino gamblers around the world
Instant Casino Chips is a site dedicated to free casino chips which players can play and complete the wager points and can withdraw the real money
USA Casino company is a very authentic site which provides information on casino games and gambling
http://www.stylecasinochips.co.uk/ is a site for casino players to wish to play casino games with a style. lots of casino games and reviews available to give the best to its players
Top Casino betting is a site for gamblers specially from USA and western world. A long list of online casinos with various merit and demerit points will teach you a better way to play at an online casino
Casino City Motors provides a very authentic and informative information about casino gambling
Play casino games 24x7 at http://www.24x7casinoresorts.co.uk/
do shopping with casino software and select the best one for you at http://www.shoppingcasinosoftware.co.uk/
Online Casino channels is a one stop shop for gamblers who wish to keep on playing the casino games 24 x 7
Narragansett Indian Tribe requesting the state legal authorities for declaration of the 2012 voting issue as unlawful in respect of installation of table games by the Twin River slot parlour


text:
Chinese archeology professor Jack (Jackie Chan) teams up with beautiful Indian professor Ashmita and assistant Kyra to locate lost Magadha treasure. In a Tibetan ice cave, they find the remains of the royal army that had vanished together with the treasure, only to be ambushed by Randall (Sonu Sood), the descendent of a rebel army leader. When they free themselves, their next stop is Dubai where a diamond from the ice cave is to be auctioned. After a series of double-crosses and revelations about their past, Jack and his team travel to a mountain temple in India, using the diamond as a key to unlock the real treasure.
Receive special offers, discounts and free movie tickets at Village Cinemas. Remember to flash your Village Movie Club card at the ticket box or log into your account when buying your tickets online to earn rewards!


text:
Cat eyeliner tutorial
Explore related topics
How To Apply Eyeliner ❤ liked on Polyvore featuring beauty products, makeup, eye makeup, eyeliner, beauty, eyes and sexy eye makeup
It's always easier to line out a cat eye then fill it in for a neater look. :)
Follow the amazing and talented @maya_mia_y and help her reach 1Million follo... | Webstagram
Use an angled brush to create the line then gel liner and mac 211 brush to fill it in!
Top 10 Eyeliner Tutorials for Irresistable Cat Eyes - Top Inspired
Our favorite (doable) Halloween makeup how-tos from YouTube
Pro tip: For lines that are perfect & precise, use an eyeliner brush like the one in the Strokes of Genius Brush Kit from L.A.B.²!
Neutral smokey eye with cat eye eyeliner
A cat eye is probably the biggest struggle for small-lidded ladies, but here's a quick and easy trick.
Detailed cat eye/winged eyeliner tutorial :)


text:
Buccaneers sign LB Lehman
TAMPA, Florida (Ticker) - The Tampa Bay Buccaneers signed linebacker Teddy Lehman on Wednesday.
Financial terms were not disclosed but the Tampa Tribune reported it was a one-year deal for Lehman, who spent his first four seasons with the Detroit Lions.
On Tuesday, Tampa Bay announced the signing of free agent linebacker Leon Joe.
A second-round pick of the Lions in 2004, Lehman's best season came as a rookie, when he registered 103 tackles while playing in all 16 games.
Lehman, 27, appeared in just nine games combined the following two seasons before seeing action in all 16 games in 2007, posting 27 tackles in a reserve role.
Yahoo! Sports Fantasy Football 2012 registration is now open. Sign up today!
Updated Wednesday, Mar 5, 2008


text:
Clarins Capital Lumière Nachtcreme Revitalisierend Trockene Haut (Crème, 50ml)
Third-party offer
This product is delivered by a third party supplier. The sales contract is concluded between you and the supplier.
Mail delivery
approx. 2–4 days
> 5 item(s) ready for shipment from external warehouse
- Unfortunately, this product cannot be collected.
If ordered immediately.
Information subject to change.


text:
This feature is free. Check out the awesome benefits of becoming a Pro User.
=FindDuplicateContent(string findDuplicateContent,
{string inCells}) : string
Finds the longest Longest Common Substring of strings in a vector compared to a reference string.
This function is very useful when writing content in Excel and you want to make sure you have written unique texts.
See blog post Excel plugin for finding duplicate content in cells for more help with this function.


text:
Coolest Homemade Carrie Halloween Costume 2
by Malorie
(White Plains, NY, USA)
My dad and I are really big horror movie buffs. My mom, brother, and sister, not so much. So, when they all left for a week-long vacation, we took the opportunity to rent a bunch of horror movies. I had read "Carrie" several months ago, and I decided to add the 1976 movie version to our list. Books are always better than movies, but I liked the movie version so much, I decided on a Homemade Carrie Halloween Costume that year.
I found a recipe online on how to make fake blood (FYI, it's red and green food coloring and corn syrup), and found a pink dress at an inexpensive store. My dad had complained that the dress was too short, but I had to explain, "Do you see how these girls dress these days, with the Ashlee, and the Lindsay, and the Paris? They all dress like strippers. It's go ho or go home." (quote from How I Met Your Mother).
When I entered the costume contest, I was up against a guy in a bloody Scream mask. So I knew I had won. Especially when I walked very slowly down that path outside, with my eyes open wide like Sissy Spacek had done in the movie.
Return to Movie and Book Character Costumes 1.
Coolest Homemade Ash from Army of Darkness Costume
by Eric B.
I made this Homemade Ash from Army of Darkness Costume last year. I found a cheap shirt at value village and ripped it a bunch and smeared makeup over it since that's all I had to make it look dirtier. In the back is a rifle I made out of cardboard in a holster also made form cardboard.
It's held on by a bracelet in the center and a few cheap belts I also got from value village. The chainsaw hand is a cardboard box that cut a hole in the end for my hand and played with a bit so it was a little less square looking. Spray painted that red and the blade silver (the chain on the chainsaw is from a hardware store, I don't remember what it is exactly), then threw some extra makeup on it and all over myself to make me look a bit more like I'd been fighting the undead. It mostly got sweated off, but the makeup was a rush job anyways (actually the whole thing was, I made it the night before).
It was nice though to have a hand free to eat cupcakes though.
Comments for Coolest Homemade Ash from Army of Darkness Costume
Click here to add your own comments
Coolest Carrie Costume 4
by Elise
(Melbourne, Australia)
My husband decided to have a horror theme for his 35th Birthday party. I decided to go as Carrie as it was one of the only horror movies I have ever seen in my life!
I actually ordered a Carrie Costume online but was so disappointed when I received it; I decided to make my own.
I bought an old dress from the Op Shop, a flower corsage from Spotlight and a wig from the costume shop. I then made my own blood with coffee, sugar, corn flour, red food colouring and green food colouring. I drenched myself with the stuff in the backyard and let myself dry off 30 mins before the party. The homemade blood also only took 2 showers to come off and didn't stain the floor or shower. Phew!
I scared everyone who walked through the door, it was such fun!
Return to Movie and Book Character Costumes 1.
Coolest Homemade Ash Costume from Army of Darkness 4
by Jeff L.
(Saratoga, New York)
Homemade Ash Costume from Army of Darkness
This Homemade Ash Costume from Army of Darkness cost me about $45. I bought a broken chainsaw from a garage sale and took out the motor so it wouldn't weigh a ton, then to Home Depot for some PVC pipe and rubber grommets to hold my hand in place. I got a screw on PVC top which I bolted to the bottom of the chain saw so I could take it on and off.
I used a bloody rag on the inside of the PVC pipe so when I unscrewed the chainsaw it looked like my hand was indeed severed. Took a belt and a tool belt and crossed them on my chest. A cheap toy shotgun from amazon.com, a blue button down shit from a thrift store, some fake blood and a little bit of make up and you done!
Return to Movie and Book Character Costumes 1.
Coolest Homemade Carrie Prom Queen Nightmare Costume 3
by Charlotte and Steve
(Boston, MA - USA)
This Homemade Carrie Prom Queen Nightmare Costume is made with a Prom dress of 70-80's style. Purchased liquid blood and dripped it so it was running down all sides. Silk roses with silk ribbon with droplets of blood. Blood on face, arms and flesh showing. Prom Queen tiara.
Prom King, 80's suit, 80's hair, king crown, prom king sash. I widened the lapel on the suit with brown felt for the 80's look and purchased a ruffled shirt from a tuxedo shop. I was lucky to find it. Rose corsage dipped in blood.
Return to Movie and Book Character Costumes 1.


text:
For Trade:
FS/FT My bass port modded white Q701 for your HD600 (UK)
Will Ship To: UK
Hi all, looking to do a straight swap for the above headphones.
Im also willing to sell for £140 including delivery.
Paypal fees must be paid by the buyer.
Willing to send first to buyers with high feedback.
Can upload photos if needed.
Edited by Jony27 - 3/19/15 at 6:34am


text:
I Bought a Vampire Motorcycle (1990) Watch Online Free
I Bought a Vampire Motorcycle (1990)
IMDB Link:
Rating: 5.6/10 (636 votes)
Directed By: Dirk Campbell
Starring: Amanda Noar, Anthony Daniels, Michael Elphick, Neil Morrissey
Duration: 101 min
Year: 1990
Genre: Comedy, Horror
Language: English
Released: N/A
|Plot: When a motorbike gang kills an occultist, the evil spirit he was summoning inhabits a damaged bike. The bike is then bought and restored, but reveals its true nature when it tries to exact vengance on the gang, and anyone else who gets in its way.
I Bought a Vampire Motorcycle Full Movie


text:
Leadership Initiatives
Coaching for Administrators
SCOE provides one-on-one coaching support for principals that is relevant to their immediate needs and respectful of the demands already being made on their time and energy. This coaching program is completely voluntary and designed as a proficiency, not a deficiency, model. Coaches are highly experienced former principals who possess strong coaching skills and can provide accessible on-site, real-time support for new administrators. They are trained in coaching models, protocols, and methods to ensure that the services they provide meet the individual needs of the principal.
Key Components & Expectations
- The district superintendent must support the principal's participation.
- Coaches and principals meet to establish goals and areas of focus for the year.
- Coaches meet with principals at the school site on a regular basis for individualized coaching conversations and planning. Coaches are available by phone and email between meetings.
- Coaches provide authentic opportunities for assistance. This may include assistance in areas such as conducting teacher observations and conferences, facilitating staff meetings, interpreting data, managing budgets, etc.
- Coaches may assist principals in locating model programs, best practices, consultant services, and other resources that relate to identified goals.
- Coaches and principals participate in an assessment of the effectiveness and value of the coaching experience as a means to refine and improve the program for future participants.
Coaching is available to schools and districts on a fee-for-service basis.
2016-17 Coaching Support Announcement Letter (pdf)
Fee Structure for 2016-17
|Type of Site
|Type of Service
|Admin/Coachee Fee
|District/ school in program improvement
|6 months of PI coaching
|District/ school in program improvement
|7 months of PI coaching
|District/ school in program improvement
|8 months of PI coaching
|District/ school in program improvement
|9 months of PI coaching
|NOT in program improvement
|6 months of general coaching
|NOT in program improvement
|7 months of general coaching
|NOT in program improvement
|8 months of general coaching
|NOT in program improvement
|9 months of general coaching
- Tara Beiden,�Division Support Assistant
(707) 522-3151,
- Karen McGahey,�Director, Leadership Development
(707) 522-3330,
- Stacie Post-Sheffer,�Administrative Specialist
(707) 524-2813,


text:
Can a vegetarian person get a good meal at this restaurant?
Can a vegan person get a good meal at this restaurant?
Is this restaurant family-friendly?
Can a gluten free person get a good meal at this restaurant?
Does this restaurant offer free wifi?
Is this restaurant good for lunch?
Is this restaurant good for dinner?
Is this restaurant good for breakfast?
Does this restaurant offer takeout or food to go?
Does this restaurant offer delivery?
Thanks for helping!
3 Days in New York City
First Time in the City
Insider's Guide - Personal Favorites: NY, NY
Dining at Park Avenue Winter (Spring, Summer or Fall) is always a treat. Yes, the restaurant is expensive but the experience is worth it. Their food is delicate and delicious and the atmosphere can't be beat. It's a very nice special occasion venue.
We had a lovely Valentine's Day meal. We sat in the bar/bistro area in a little corner banquette. While it wasn't as pretty as the main dining room, it served the same delicious menu and offered attentive, but not overly solicitous, service. (The soundproofing was also very good.) The "winter" menu wasn't too heavy. Even though a lot of the...
Beautiful restaurant with lovely decor in shades of winter white, however, VERY LOUD and thus not suitable for conversing with others in my 7 person group. Friendly and accommodating staff. Despite the large Valentines Day crowd, the service time was very reasonable and the food reached the table at an appropriate temperature. Prices are comparable to other restaurants in the...
We enjoyed a truly wonderful meal here with great service as well a wonderful food in an attractive atmosphere.
We were drawn in by a dish on the menu. Broccoli covered by Cheetos. Please don't let that turn you away! It was actually tasty, and our inquiring minds were satisfied. The restaurant changes their menu (and decor) with the seasons,...
Stopped at this restaurant for dinner while on a long weekend excursion. My lovely girlfriend has made the reservation having been here in the past. The decor was lovely, our table situated next to another couple's who we engaged in lively conversation (after some time together, just the 2 of us, of course). We started with a cocktail and later,...
Friends took me here for Christmas Dinner and it was perfect. The drinks were amazing to start and the service was impeccable. The food was insanely good. I had the steak which was done perfectly, but the cheesy roasted broccoli was to die for. It was so smoky and cheesy it was literally the best broccoli dish I have ever...
Excellent food, amazing unusual combinations of ingredients! Oxtail orecchiette dish was superb. Everything I tasted was delicious.
We scooted in here late on a Friday for cocktails and were not disappointed. I had the 'Fezziwig', and my friends each tried a different fancy cocktail on the menu of specials. There was only one dog in the bunch - a strange, smoky concoction called 'Yellow Snow'. Well, you know what they say about yellow snow...
Other than that,...
My first visit, the food was fine, but the noise was outrageous. The table service was attentive -- the hostesses rude. There was nothing particularly special about this restaurant and, in NYC, that matters because there are endless other choices! We went for Restaurant Week and they are generous in the number of menu selections...it wouldn't be my choice to...
Visiting from out of town, we made reservations for 9p on a Tuesday. We did not realize that we had made reservations for the 'dinner party' and we couldn't be happier with our mistake!
We had a greeting glass of champagne and a beautiful plate of hors d'oeuvres. The tables on either side of us asked what we had ordered......
Own or manage this property? Claim your listing for free to respond to reviews, update your profile and much more.


text:
Sometimes the art of seduction is subtle and surreptitious, and sometimes it's just mailing someone a sexy picture of yourself once a day for four years. Use the power of the pose with this Groupon.
$71 for a Boudoir Photo-Shoot Package ($652 Value)
- One-hour in-studio boudoir photo session
- Five retouched digital images
During their boudoir shoot, subjects can don up to three sultry outfits. Afterward, they receive five retouched, digital images uploaded to their personal USB device.
Maya Mouis - Photo Atelier
Maya Mouis has shot models in business sheaths, in high-fashion fringed crop tops, and frolicking in their bikinis on the beach. Since its inception in 2000, however, her eponymous management company and photography studio has encompassed more than eclectic photo shoots. She and her team also aid models with agency placement and teach them to stride down the runway with style.
Customer Reviews
7901 4th St. N
Suite 324
St. Petersburg, FL 33702
+17279452242Get Directions


text:
Hi! My name is Norma. I was born in Bogota, Colombia. I fell in love with music when I was a little girl, so I began taking music lessons when I was 8 years old. First, I took violin lessons, and after four years decided to switch to the piano.
I also loved to sing. So I took piano lessons and singing lessons at the same time, and after a while I dedicated myself completely to singing. After that I graduated from my music school with a degree in vocal technique.
I have sung in several venues in Colombia and in the US. as a solo artist and as a band member as well.
I also worked at the School of Rock in Coral Springs, Florida for four years, which gave me much more experience with rock music and teaching kids of all ages.
I really hope I can help you reach your goals, and to love music the same way I do.
Director of the music program for little kids (ages 3-5) at the School of Rock in Coral Springs.
I was the vocal instructor for all their programs, working with kids of all ages and with adults as well. I was in charge of teaching them the right technique to help them get ready for the season shows where they would sing and play music with other students.
Member of Legato - It is a choir that sings all sorts of Colombian and Latin American traditional songs, religious music, and Christmas carols. Legato is well known for its Christmas carols repertoire. We recorded an album with the most popular carols in 2001. In 2002, Legato sang in "Carmen" by Georges Bizet, with the Opera Studio Foundation in Bogota.


text:
|Home | About | Journals | Submit | Contact Us | Français
The recent structure and associated biochemical studies of the metazoan-specific p300/CBP and fungal-specific Rtt109 histone acetyltransferases (HATs) have provided new insights into the ancestrial relationship between HATs and their functions. These studies point to a common HAT ancester that has evolved around a common structural framework to form HATs with divergent catalytic and substrate binding properties. These studies also point to the importance of regulatory loops within HATs and autoacetylation in HAT function. Implications for furture studies are discussed.
The genetic material present in the nucleus of eukaryotic cells is packaged into chromatin, which functions as a dynamic scaffold for the regulation of various nuclear processes including DNA transcription, replication, repair, chromosome segregation, and apoptosis. The basic, repetitive unit of chromatin is the nucleosome core particle, a nucleoprotein structure that contains 147 base pairs of DNA wrapped around a histone octomeric core of a histone H3/H4 heterotetramer and two histone H2A/H2B heterodimers. Together with the H1 linker histone, nucleosome core particles form arrays of compacted higher-order chromatin structures that allow the entire human genome with a linearized length of more than 1 meter to be packed into a nucleus with a micrometer-scale diameter. Compacted chromatin restricts the access of many DNA regulatory proteins, thus neccesitating the need for chromatin regulatory proteins to facilitate DNA regulatory activities. Of the proteins that regulate chromatin function, the enzymes that post-translationally modify the histone proteins, particularly on the N-terminal histone tail regions, form the largest family. Histone acetyltransferases (HATs) were the first family of histone modification enzymes characterized at the molecular, biochemical and structural levels.
HAT enzymes catalyze the transfer of an acetyl group from the co-factor acetyl-coenzyme A (acetyl-CoA) to the ε-amine of a substrate lysine side chain. Since the isolation and characterization of the Tetrahymena Gcn5 HAT in 1996 [1], a large number of HATs have now been identified and characterized. To date, nuclear HATs can be categorized into four major families based on primary sequence homology: Gcn5/PCAF (General control nonrepressed protein 5 and p300 and CBP associated factor); MYST (named for the founding members MOZ, Ybf2/Sas3, Sas2, and Tip60); p300/CBP (protein of 300 kDa and CREB Binding Protein); and Rtt109 (Regulator of Ty1 Transposition gene product 109). Other putative HATs that have been reported include ATF-2 [2], TAF250 [3], nuclear steroid receptor coactivators [4,5], and more recently the circadian CLOCK protein [6], but their enzymatic properties have not been rigorously characterized. In this review, we will describe the two HAT families that have been most recently characterized, p300/CBP and Rtt109, with a particular focus on their strucutres and chemistry with implications for HAT evolution and function.
The p300 and CBP (CREB binding protein) paralogs were originally identified as binding partners of the adenovirus early-region 1A (E1A) protein [7,8], and the cAMP-regulated enhancer (CRE) binding proteins [9], respectively. These proteins were later shown to function as transcriptional adaptors, and, about a decade ago, they were shown to harbor HAT activity [10,11]. p300 and CBP HAT domains have >90% sequence identity and are conserved in metazoans with many overlapping functions and will henceforth be referred to as p300/CBP. p300/CBP has multiple domains and, in addition to the enzymatic HAT domain, contains other protein interaction domains including three cysteine-histidine rich domains (CH1, CH2 and CH3), a KIX domain, a bromodomain, and a steroid receptor coactivator interaction domain (SID, also the SRC-1 interaction domain). p300/CBP not only catalyzes the acetylation of all four core histones, but has been reported to acetylate over 70 other proteins and itself (Table S1). Therefore, p300/CBP appears to be a versatile, and perhaps rather general, transcriptional integrator.
Abberrent p300/CBP activity has also been observed in various diseases. For example, Rubinstein-Taybi syndrome (RTS) is a developmental disorder caused by heterozygous germline mutations in the CBP or p300 genes [12,13]. p300/CBP gene mutations have been detected in human tumors with loss-of-function point mutations found in colorectal, breast, ovarian, oral, gastric, lung, and pancreatic carcinomas [14–16]. p300/CBP involved chromosome translocations have been observed in acute myeloid leukemia (AML) and in hematological disorders such as myeloid/lymphoid or mixed lineage (MLL) [17]. p300/CBP also functions as a transcriptional cofactor for proteins involved in tumorigenic pathways, including oncoproteins (such as myb, jun, and fos), transforming viral proteins (such as E1A, E6 and large T antigen), and tumor-suppressor proteins (such as p53, E2F, Rb, Smads, and BRCA1) [17]. p300/CBP may also contribute to respiratory epithelial carcinogenesis via cyclin D1, cyclooxygenase-2 (COX-2), and activator protein-1 (AP-1) [18]. More recent studies have linked p300/CBP to other diseases like progressive neurodegenerative diseases (such as Huntington Disease) [19], Kennedy's disease [20], Alzheimer's disease [21], cardiac disease [22], and fibrosis [23].
In contrast to the exclusive presence of p300/CBP sequence homologues in metazoans, Rtt109 sequence homologues are only present in fungi. Rtt109 was first identified to be a budding yeast regulator of Ty1 transposition that also plays an important role in the DNA damage response to genotoxic agents [24,25]. Recent genomic and proteomic screens as well as a more directed effort led to the observation that Rtt109 promotes genome stability and resistance to a variety of DNA-damaging agents through the direct acetylation of histone Lys56 of histone H3 (H3K56), a residue positioned at the DNA entry and exit points of the nucleosome core particle, during S-phase [•26, •27, •28, •29]. Rtt109 was subsequently reported to also acetylate H3K9 [•30].
Similar to the p300/CBP family, Rtt109 has no detectable sequence homology to other known HATs. Unlike other HATs, Rtt109 does not contain additional protein interaction domains and requires the presence of one of two histone chaperone proteins, Asf1 or Vps75, for HAT activity [•27, •29, •30, 31, 32].
In early 2008, we reported on the crystal structure of the p300 HAT domain in complex with a Lys-CoA bisubstrate inhibitor and accompanying biochemical analysis of the enzyme [••33]. The overall fold of the p300 HAT domain consists of a central β-sheet composed of 7 β-strands surrounded by 9 α-helices and several loops (Figure 1c). Despite its sequence divergence from other HATs, a central core region of the p300 HAT domain, associated with acetyl-CoA cofactor binding, overlays well with the corresponding regions of the Gcn5/PCAF [34] and MYST [35] HATs (Figure 1a,b). This structurally conserved core region corresponds to the A, B and D sequence motifs of the GNAT (Gcn5 related N-acetyltransferase) superfamily of proteins reported by Neuwald and Landsman [36]. In contrast, the structural elements that flank the central core diverge significantly between the three HAT familes. Two other features also distinguish p300 from other HATs. First, the acetyl-CoA binding site of p300 is more buried than other HATs. This is largely due to the presence of a p300-specific L1 loop that covers one side of the cofactor and contributes to about one third of the protein-cofactor interactions (Figure 2a). This loop was also shown to be important for p300 catalysis. Second, the surface charge of the p300 HAT domain, particularly proximal to the lysine substrate binding site, is largely electronegative, compared to the more neutral character of the corresponding substrate binding sites of other HATs. Indeed, two shallow electronegative patches, one harboring the lysine moiety of the Lys-CoA inhibitor (P1) and another located about 10 Å away (P2) were shown to be mutationally sensistive for histone binding and catalysis (Figure 2c). Correlating with the importance of the P1 and P2 pockets, positively-charged residues are typically present within 3–4 amino acid residues (about 10 Å) upstream or downstream of the acetylated lysine residues of known p300/CBP substrates [37]. The promiscuous substrate specificity of p300 relative to other HATs can be accounted for by such a shallow and presumably versatile P2 pocket governing substrate recognition. An interesting property of the p300/CBP HATs is the presence of a highly basic autoacetylation loop that is hyperacetylated in the activated form of the p300/CBP HAT [•38] and that has been proteolytically cleaved in the current p300 HAT domain structure [••33]. We propose that this highly basic loop sits in the electronegative substrate binding site to block lysine substrate binding and is released from this site upon autoacetylation, as schemetically depicted in Figure 3a.
Recent enzymatic studies on the p300 HAT domain is consistent with a Theorell-Chance (or "hit and run") catalytic mechanism that is distinct from other HATs. This mechanism, as it applies to p300, invokes that during catalysis, there is no stable ternary complex formed during the reaction. Rather, the p300 protein first forms a stable complex with the acetyl-CoA cofactor and then the positively charged substrate lysine side chain from the protein substrate transiently binds to the negatively charged P1 pocket and departs immediately after acetyl transfer. Such a mechanism differs from the classical ordered Bi-Bi ternary complex mechansim employed by the Gcn5/PCAF [39] and the ternary [40] and ping-pong mechanisms [35] that have been proposed for the Esa1 member of the MYST family of HATs. The Theorell-Chance mechanism proposed for p300/CBP is consistent with the broad substrate specificity of p300 as it does not require a specific substrate binding pocket. Structure-based p300 mutagenesis studies also identify two critical catalytic residues: Tyr 1467 that likely funcitons as a general acid to protonate the CoA leaving group, and Trp1436 that likely helps steer the substrate lysine into its binding site (Figure 2a). Interestingly, p300 does not critically depend on a specific Asp/Glu general base for catalysis, similar to serotonin N-acetyltransferase [41], but unlike the Gcn5/PCAF [34,42] and MYST [35] HATs that employ glutamate residues for this purpose.
The structure of p300 allows for a rationalization of several p300/CBP-inactivating mutations that have been observed in various cancers [14–16]. For example, the catalytic Trp1436 residue is mutated to cysteine in lung cancer, as is Arg1410, which plays a key role in acetyl-CoA cofactor binding. In addition, Asp1399, a residue important for the appropriate conformation of the L1 loop (Figure 2a), is mutated to a tyrosine residue in colon cancer.
Shortly after the structural determination of the p300 HAT domain, we reported on the crystal structure of the Rtt109 HAT domain bound to the acetyl-CoA cofactor [••43]. Despite its sequence divergence from other HATs, the Rtt109 structure reveals a strucutrally conserved core region for CoA binding. Unexpectedly, the rest of the Rtt109 domain also looks remarkably similar to p300 with an overall r.m.s.d of 3.5 Å for 236 out of 354 Ca atoms (Figure 1d). This similarity extends to the L1 loop where an Asp89-Lys210 salt-bridge (reminiscent of the Asp1399-His1451 salt-bridge in p300) is essential for holding the loop in position for acetyl-CoA cofactor binding (Figure 2b). Given that the Rtt109 and p300/CBP HAT family only exists in fungi and metazoans, respectively, these structural similarities suggest an evolutionary link between p300/CBP and Rtt109.
Despite the structural similarities between p300 and Rtt109, several biochemical properties of the two enzymes suggest that they diverge significantly at the functional level. Specifically, the surface charge of Rtt109 proximal to the lysine binding site (Figure 2d) is unlike the electronegative surface of p300 (Figure 2c) and, in fact, more like the apolar surfaces of the Gcn5/PCAF and MYST family of HATs. Indeed, unlike the broad substrate specificity of p300/CBP, Rtt109 appears to be quite selective for H3K56 [•27, •28, •29] and H3K9 [•30]. The potent p300 inhibitor, Lys-CoA [44] does not show detectable inhibition of Rtt109 [••43]. The mechanism of acetyl transfer catalyzed by Rtt109 also appears to be distinct from that of p300, as well as the Gcn5/PCAF and MYST HATs. Similar to p300, Rtt109 does not contain an appropriately positioned glutamate residue in the active site that might function as a general base for catalysis, as seen for the Gcn5/PCAF HATs. However, dissimilar to p300, the two important catalytic residues of p300, Trp1436 and Tyr1467, are not structurally conserved in Rtt109 (Figure 2a,b). Interestingly, although tyrosine and tryptophan residues of Rtt109 (Tyr199 and Trp222) have been shown to be important for catalysis, they are in different positions in the three-dimensional structure from the corresponding catalytic residues in p300 and appear to play different catalytic roles (Figure 2b). Kinetic analysis of Rtt109 also reveals an unusual sigmoidal histone H3 substrate concentration dependence at fixed acetyl-CoA that fits to a Hill equation with a Hill coefficient of 3, suggesting a high degree of cooperativity of the histone substrate in the acetylation reaction. Although the delineation of the precise catalytic mechanism employed by Rtt109 requires further study, it is already clear that Rtt109 employs a catalytic mechanism that differs from other HATs and is consistent with a more complex nature of protein substrate recognition.
Like p300, Rtt109 has been shown to acetylate itself [45]. Indeed the structure of the Rtt109/Ac-CoA complex reveals that a partially buried lysine residue (K290), located about 8 Å away from the active site of the enzyme, is acetylated (Figure 3b). Moreover, mass spectrometry data on bacterially produced recombinant and yeast produced Rtt109 protein reveals that this lysine is autoacetylated in vitro and in yeast cells [••43]. Although the functional consequence of this autoacetylation is still unclear, it is interesting to note that in addition to Rtt109 and p300/CBP, other HATs, including Esa1 [40] and PCAF [46] have been shown to undergo autoacetylation. These observations point to the possibility that the autoacetylation of HATs may play conserved functional roles in regulating HAT funciton.
A unique feature of Rtt109 that distinguishes it from p300 and other HATs, is that it requires the association of histone chaperones, Asf1 and/or Vps75 for catalysis [•27, •29, •30, 31]. We suggest that the binding of these chaperones may help present the H3 substrate to Rtt109 protein, which is consistent with the observation that the addition of excess Vps75 to a stoichiometric Rtt109/Vps75 complex inhibits histone H3 acetylation by Rtt109 [••43]. The histone chaperone requirement for Rtt109 HAT activity may be related to the fact that Rtt109, unlike other HATs, does not contain other associated domains to interact with other chromatin modifiers.
During the review of this manuscript, two additional manuscripts describing analogous crystal structures of Rtt109 were reported [••51, ••52]. Both studies utilized protein constructs with internal loop deletions similar to what we had described (delta 130–179) and reveal essentially the same Rtt109 structure. Moreover, the study by Stavropoulos et al. also confirmed that this particular loop region is essential for Vps75 histone chaperone binding [••43, ••51]. Also similiar to the initial Rtt109 structure report is the finding that K290 of Rtt109 is acetylated [••51, ••52]. Interestingly, while our study found that a K290R mutant is wild-type for both H3K56 acetylation and sensitivity to genotoxic stress in vivo, the more recent studies show that mutation of K290 reduces the ability of Rtt109 to acetylate H3K56 in vitro [••52] and in vivo [••51]. These apparently conflicting results may be related to the fact that we employed a K290R mutant in the context of an intact Rtt109 protein using a W303 yeast strain [••43], while Stavropoulos et al. employed K290 mutants in the context of a (delta 128–170) loop deletion using a different BY4741 yeast strain [••51]. Lin and Yuan also found that the K290R Rtt109 mutant is inactive in vitro towards an Asf1/H3-H4 substrate [••52]. Additional experiments are clearly needed to resolve the importance of K290 acetylation in Rtt109 function.
The recent structural analyses of the p300 and Rtt109 HATs further extend the notion that, despite the lack of sequence conservation, HATs may contain a "universal" conserved central core region for acetyl-CoA binding but divergent flanking regions (Figure 1). These more divergent flanking regions appear to be important for HAT-specific functions. For example, these flanking regions play a key role in histone substrate binding by Gcn5 [39] and play a role in nucleosome binding by the MOZ member of the MYST HAT [47]. The conserved L1 loop in p300 and Rtt109 plays an important role in acetyl-CoA cofactor binding and possibly also histone substrate binding and catalysis. With regard to catalysis by HATs, it is noteworthy that they employ different catalytic mechanisms despite the presence of a strucutrally conserved core region. This may reflect the fact that acetyl transfer between a thioester and an amine is kinetically and thermodynamically facile and can be readily catalyzed by positioning and orientation using various easily evolved strategies. The finding that different HATs employ different catalytic mechanisms argues favorably for the prospect of preparing small-molecule HAT-specific inhibitors, an important consideration given that HATs such as p300/CBP and MOZ [17,48] have been implicated in human disease. We would also note that the design of alternative therapeutics that rescue HAT-inactivating mutations [49] may also be aided by the structure of p300. Finally, the lack of sequence conservation among HATs and the relatively recent identification of Rtt109 as a HAT, suggest that other HATs are likely to be uncovered and tools such as novel proteomic reagents [50] are needed to aid in discovery.
Publisher's Disclaimer: This is a PDF file of an unedited manuscript that has been accepted for publication. As a service to our customers we are providing this early version of the manuscript. The manuscript will undergo copyediting, typesetting, and review of the resulting proof before it is published in its final citable form. Please note that during the production process errors may be discovered which could affect the content, and all legal disclaimers that apply to the journal pertain.
Papers of particular interest, published within the annual period of review, have been highlighted as:
• of special interest
• • of outstanding interest
PubMed Central Canada is a service of the Canadian Institutes of Health Research (CIHR) working in partnership with the National Research Council's national science library in cooperation with the National Center for Biotechnology Information at the U.S. National Library of Medicine(NCBI/NLM). It includes content provided to the PubMed Central International archive by participating publishers.


text: Blockchain-based marketplace DeBuNe, bitcoin wallet Cryptosigma and blockchain equity issuer Otonomos, have been accepted to the first batch of Startupbootcamp (SBC) Fintech Singapore's accelerator program. The startups will be given funding, free office space, access to business support services and a large network of industry experts and venture capitalists.The three digital currency startups join seven other startups in the program, which are made up of peer-to-peer wallets, money management apps, a social network for financial trading and more. All of the startups will receive three months of acceleration, 24,000 Singapore dollars (about $18,000 USD) and access to pilot customers, industry data, APIs and capital from SBC partners, such as DBS Bank, MasterCard and Route 66 Ventures."Since the beginning of the year, we have scoured the Asia Pacific and the globe for the most fascinating, innovative and promising fintech startups," said Startupbootcamp FinTech Global COO, Markus Gnirck. "With 300 applications it shows that fintech in Asia is on the rise to tackle local problems with the potential for global scale. We have met close to 200 startups, visited 12 financial hubs across APAC and beyond. So we feel confident that the 10 teams selected showcase the very best that financial services and technology has to offer."


text:
Karnataka Medical Council
Regulating doctors, ensuring good medical practice
"Renewal Certificate not received(Renewal done before October 2016)-Contact 7847849073,7411472373 or Mail at firstname.lastname@example.com, Online payment
related Queries-Contact 9591995874"
"Any discrepancy or about the correction on Preliminary renewal report of the registered medical practitioners of KMC, Kindly write to us at firstname.lastname@example.com within 15 days. On the same basis revised list will be published.(Below List is updated by 18th Jan 2017)"
Test your knowledge of ethical guidance for doctors - visit Good Medical Practice in Action.
If you have concerns about a doctor, our interactive Patients' help site can help.
Your access to and use of this website ("Site") is
subject to your compliance with all applicable
laws and the following terms and conditions.
Monday - Saturday : 10:30 AM to 5:00 PM
Holidays : Second Saturday's of month
and Government holidays
  Address:#16/6, Miller Tank Bed Area,
Bangalore -560052.
+080 22200888.
  Fax:+080 22200300.
  Website : www.vworks.co.in
Copyright © 2017 KARNATAKA MEDICAL COUNCIL . All rights reserved.


text:
Evidence of Early Trade Routes? Circa 80,000 BCE
Nassarius gibbosulus shell beads were discovered in Grotte des Pigeons, Taforalt, Morocco more than 40 km (25 mi) from the Mediterranean Sea, where they originated. "By 40,000 years ago, humans were transporting decorative shells—and perhaps trading them—over areas of more than 500 km (310 mi)" (http://humanorigins.si.edu/evidence/behavior/ancient-shell-beads, accessed 05-10-2010).
Filed under: Commerce / Trade, Human Origins, Prehistory


text:
Is this restaurant good for business meetings?
Is this restaurant good for lunch?
Does this restaurant accept reservations?
Is this restaurant good for dinner?
Is this restaurant good for brunch?
Can a vegetarian person get a good meal at this restaurant?
Can a gluten free person get a good meal at this restaurant?
Can a vegan person get a good meal at this restaurant?
Does this restaurant offer free wifi?
Does this restaurant offer delivery?
Thanks for helping!
Had a great Sunday after Church lunch. They have great steaks. Great salad bar with good variety. Great pies also.
We all had steak (of course!) and it was cooked correctly and seasoned pretty well. Salad bar was small, but had a decent selection. Had the peanut butter pie for dessert and it was quite delicious! Service was excellent and overall this was a good restaurant.
The steaks we had were prepared perfectly, and at a price that was reasonable as well. Not what I would have guessed from the outer appearance of the building, but definitely a first rate steak house.
The food was good and the service was very friendly. The grill the steaks on wood fired grill which adds to the flavor. The portions were good and the peanut butter pie was excellent.
We spent October 14-16, 2016 in the Cave City - Horse Cave, KY area! Totally enjoyed my meal at Sahara Steak House! Hope to return there sometime! :)
I ordered the sirloin which was quite tasty and good how I wanted it (medium rare). The salad bar that comes with it was fair, pretty basic stuff, without a lot of frills. Their beef veggie soup, that is part of the salad bar was quite good with just a touch of spiciness. The service was okay, I think our...
The staff here were friendly and helpful. They were able to cater to me by preparing my meal away from all the allergens I cannot come into contact with.
Great food. Even better service from Monica. Steaks spot on for temp. Get the peanut butter pie..not just the slice...get the whole pie. Trust me you will want more!
This is a casual steakhouse with good food. It had a good selection of sides. Biggest disappointment is that it has no wine or beer apparently because this is a dry county or state - not sure which. If we went back, I'd be tempted to take my own but I don't know if that's allowed. Only real slip up...
We were at Sahara for lunch and their lunch specials are great!!! The shrimp are large and fried to perfection. The steak fries were great!!! Soup and salad was included with the lunch special. I can't say enough about the salad the potato and macaroni salads were both homemade and so good!!! This is a must add to your dining...
Own or manage this property? Claim your listing for free to respond to reviews, update your profile and much more.


text:
Flight returns after being 'hit' by laser pointer
A Virgin Atlantic flight to New York was forced to return to Heathrow Airport after a laser beam was pointed at the plane - prompting urgent action in the cockpit, said British police.
The police were notified that a laser was aimed at a commercial aircraft that had taken off from Heathrow on Sunday evening, said a police spokesman.
Audio of the plane's exchange with air traffic control describes one of the pilots having a "medical issue" following the incident, which occurred "six or seven miles" west of Heathrow, writes Sky News.
- The decision to turn the plane were taken by both pilots after one of them felt unwell after the incident, writes the airline, Virgin Atlantic, in a statement.
The plane flew over Ireland when the pilots asked to return.
It is not uncommon in the UK that people are aiming laser pointers at aircraft. Every year there are reports of hundreds of incidents.
Comment below.
Comments at Speisa are unmoderated. We do believe in free speech, but posts using foul language, as well as abusive, hateful, libelous and genocidal posts, will be deleted if seen. However, if a comment remains on the site, it in no way constitutes an endorsement by Speisa of the sentiments contained therein.comments powered by Disqus
VIDEO: The Secretary General of the Council of Europe - on radical Islam
The Secretary General of the Council of Europe, shows us what he knows about Islam, which is less than zip.


text:
Art Est. Art School
Fine Art, Oil Paintings, Art Classes
Art Est. Art School's annual January Summer Art School offers a chance for adults to kick start a creative new year. Our Summer Art School has a great range of workshops designed to suit all levels of artists and interests.
There's something for everyone, whether you want to:
learn to paint
learn to draw
consolidate your existing skills
or dip your creative toe into a new media
All Summer Art School workshops are suitable for HSC and senior school art students too.
Visit our website to find out more. www.artest.com.au
Places fill quickly, so don't leave it too late to enrol!
We are located in Sydney's inner west and accessible by easy public transport from the city.
Print this page
Are your kids stuck for something to do these Easter Holidays? Art Est. Art School and Gallery have a range of fun creative art workshops on from April 7 -17.
Corporate Team Building Event - Art Workshops
Art Classes for Children.
School Holiday Art Classes for Children | School Holiday Activities for Kids
Imaginative art parties for all ages led by professional artists at our beautiful studios.
A huge range of creative small art courses and workshops led by professional artists at affordable prices.
Create your free Hotfrog business profile
Follow Hotfrog on:
Share on:
Hotfrog Small Business Hub


text: Newcastle-based Dickinson Dees is preparing to launch its first office in London. The firm is understood to be finalising terms for a new office near Blackfriars, with management finalising the lease agreements for its new serviced premises. The new office, which is not initially expected to base lawyers in London full time, will focus on Dickinsons' clients in the transport, projects, real estate and construction sectors.


text:
Che Lulu Guesthouse
Show Prices
Show Prices
Show Prices
Show Prices
Show Prices
Show Prices
Show Prices
Show Prices
Show Prices
Show Prices
- Open Bayres Hostel
- Miravida Soho Hotel and Wine Bar
- Terrazas de Uriarte Apartments
- Hollywood Suites & Lofts
- Esplendor Palermo Soho
Show Prices
Show Prices
Show Prices
Show Prices
Show Prices
Trendy Neighborhood, So-So Hotel
We spent our first stay in BsAs in this hotel. It's tucked away in the Palermo Nuevo Neighborhood in BsAs and there are a lot of nice restaurants and such around. As for the accommodations, I think we would have found better in the area. The rates are around $50 US which for BsAs is a little pricey. I would have expected a bit more than what we got. The staff was very and friendly and helpful and the breakfast in the morning was delish, but that was about it.
Unique Quality: The location was nice - a good distance from downtown BsAs if you were going to do that stuff.
Directions: Palermo, Palermo Nuevo
MTV house....better on MTV
Che Lulu is incredibly hard to find. Our remis driver had to stop and ask directions no fewer than 4 times, that's even after we showed him where it was on a map. It's a cute guesthouse, a bit on the outskirsts of Palermo Viejo, near the railroad tracks.
Despite it's cuteness, I would NOT stay there again. We arrived during a heat wave, only to find that the place had no a/c. Also, it was cramped and crowded, although the others staying there were very nice. We had one of the two first floor rooms because they were the only ones en suite, and it was essentially a basement room...no windows, only the sliding glass front door which lead to the little courtyard. And, despite the fresh flowers daily, it was a basement.
Watch charges for extras there. A cell phone call cost me U$S1 per minute. (Luckily I only talked for 4 minutes), and a small water (con gas) is also U$S1....es caro, no?
Unique Quality: The place is young, hip, and cute.
Also, while we were there, they were filming some quaisi-reality tv show, with some Argentine supermodels. (Think Paris Hilton and Nichole Ritchie, but with even LESS talent.) If hanging around supermodels is your thing, you may get lucky. (Yeah, lucky, just like us...)
- 1
Nearby Che Lulu Guesthouse
Nearby HotelsSee all 1187
Open Bayres Hostel 232 feet away
Hostel Hogar al Sur 520 feet away
Miravida Soho Hotel and Wine Bar 0.1 miles away
Terrazas de Uriarte Apartments 0.1 miles away
buenosairestudios 0.1 miles away
Nearby AttractionsSee all 156
Evita Museum - Museo Evita 0.8 miles away
Bosques De Palermo - Palermo Park 0.9 miles away
Lagos de Palermo 1 miles away
Avenida Santa Fe 1.2 miles away
Museo Jose Hernandez 1.4 miles away
Che Lulu Guesthouse
We've found that other people looking for this hotel also know it by these names:
- Che Lulu Guesthouse Hotel Buenos Aires
Address: Emilio Zola 5185, Buenos Aires, 1425GHA, Argentina
Amenities at Che Lulu Guesthouse
- Continental Breakfast
- Suites
- Shuttle Service
- Wheelchair Accessible
- Room Service
- Bar / Lounge
- Pets Allowed
- Free High Speed Internet
- Kitchenette
Sponsored Listings
Buenos Aires Travel Forum
Need advice about Buenos Aires, Argentina? Visit the Travel Forum for Buenos Aires and ask our Answer Gurus.


text:
Posted On 2005-11-1 by FortyPoundHead
Keywords: OL2000 Outlook Create Message
Views: 1417
Rating: / 5.00
Here's a fast way to create a new e-mail message in Outlook: Double-click a blank area of the Inbox and a new message will automatically open up.
Editor's Note: This tip also works in the blank areas of the Contacts, Tasks, and Notes folders.
FortyPoundHead has posted a total of 1975 articles.
You can find more information from FortyPoundHead by visiting .
No comments on this post yet!
Do you have a thought relating to this post? You can post your comment here. If you have an unrelated question, you can use the Q&A section to ask it.
Or you can drop a note to the administrators if you're not sure where you should post.


text:
Scott Garceau
Email: firstname.lastname@example.com
Scott co-hosts The Scott Garceau Show, an afternoon drive-time Sports Talk Show on Baltimore's 105.7 The Fan that is also telecast on MASN. A member of the Pro Football Hall of Fame Board of Selectors, he is one of 44 members that meet each year at the Super Bowl to select the Hall of Fame inductees.
Garceau: Which Orioles Are All-Star Worthy?
Here are six Orioles who've earned a trip to San Diego with their 2016 play.
Garceau: Orioles Look Good Through Third Of The Season
After taking 2 of 3 from the Yankees this weekend the Orioles are back in first place in the A.L. East, percentage points ahead of the Red Sox. A third of the 2016 season is in the books (plus 1-game) and the Orioles have the second best record in the league and fifth best record in baseball.
Garceau: Wieters Celebrates A Big Birthday Win In The West
If Disneyland is the happiest place on earth, the Orioles bench was about to become a close second.
Garceau: Orioles At Quarter Mark, 4 Players Up & 4 Players Down
The Orioles start the road trip with a 24-15 record, they lead the AL East by percentage points over Boston and their .615 win percentage is the best in the American League and second to only the Cubs (.715) in all of Major League Baseball. The first quarter of the season has included two 7-game win streaks.
Garceau: Orioles Already Show Postseason Potential
Garceau says, "I know 33 games is just a small slice out of a 162 game pizza, so let's just call it 'so far so good.'"
Garceau: Tunsil And Jack Catch Cold Draft
A few weeks ago massive Ole Miss Tackle Laremy Tunsil was the popular choice to be the first pick in the entire draft.
Garceau: Breaking Down Ravens' Past Draft Picks
The Rams and Eagles have traded up and are expected to grab quarterbacks with the first two picks, so if the Ravens stay at six they'll get one of the top four players on their board. The last time the Ravens picked in the top six they grabbed Jamal Lewis with the 5th pick in the 2000 draft.
10 Things To Know About Joey Rickard
He's our favorite Orioles player we probably don't know much about. In an effort to close the gap for his fans we present a closer look at Joey Rickard.
Garceau: MLB National League Predictions
Time to throw darts at the National League; in our American League preview we picked the Blue Jays, Royals and Astros to win Division titles.
Garceau: MLB American League Predictions
It's time to play ball and that means it's time for my annual MLB picks.
Garceau: Breaking Down NFL Rule Changes
Opponents of the automatic ejection rule wonder if it'll lead to cheap shots as players attempt to get an opponent to retaliate after getting an earlier misconduct penalty.
Garceau: Best And Worst Case Scenarios For New Ravens
This off-season it's more like "right player, right now!" Let's take a look at the three veterans the Ravens have added.


text:
Full length, full flight video from gate to gate onboard Flybe Embraer 175 G-FBJF, operating flight BE1858 from Birmingham (BHX) to Berlin Tegel (TXL) on 25 November 2014. *Every minute of the flight included from gate to gate*
The flight begins on the ground in Birmingham with the aircraft being de-iced on an icy morning. We board the aircraft 20 minutes after the scheduled departure time, and once onboard are informed by the captain that due to the delay we have missed our slot into Berlin and we must wait for a further 40 minutes.
We finally push back an hour late from the stand at Birmingham, taxying out to runway 33. We depart to the north breaking through the thick fog within seconds, to a beautiful sunny day above. We make a right turn towards the east coast of the UK, crossing the North Sea before heading across the Netherlands and into Germany, where thick cloud starts to develop below. During the flight I have included some shots of the cabin and the inflight service. We make a right turn and begin our final approach, with the landing gear coming down above the clouds, before we see the last of the sunshine and drop into the foggy day below, emerging from the cloud just a few seconds before touching down on runway 26R. We taxi to our remote stand where today's flight ends.
Video taken from seat 21A.
Airline: Flybe
Flight: BE1858
Aircraft: Embraer E-175 G-FBJF
From: Birmingham (BHX)
To: Berlin Tegel (TXL)
Departure: 10:41
Arrival: 13:09
Flight Time: 01:28
Seat: 21A
Flight Path: http://goo.gl/xPnO22
Please enjoy the flight and feel free to subscribe/comment!
GoPro Hero 3


text:
Rca Drc288su Driver Download
Rca Drc288su Driver Details:
Rca Drc288su File Name: rca_drc288su.zip
Rca Drc288su Driver Version: 196Qq
Rca Drc288su ZIP Size: 127.kb
Manufacturer: Rca
Scan Status: OK
Rca Drc288su special revision for: Windows XP Media Center Edition 2003 32 bit, Windows XP 64-bit Edition 32 bit, Windows RT 32 bit, Windows Vista Enterprise (Microsoft Windows NT 6.0.6000.0) 32 bit, Windows 7 Enterprise (Microsoft Windows NT) 64 bit, Windows XP Professional N 64 bit
Rca Drc288su Download Stats:
Direct Downloads: 140
Most Recent Download: 2/22/2017
Managed Downloads: 6608
Most Recent Download: 2/21/2017
Download Mirrors: 2
Current Delay: 10 Seconds
Driver License: GNU
Direct Download Success Stats:
Reports Issued By 131/140 Users
Success Reported By 22/131 Users
Driver Download Score74/100
Driver Installation Score69/100
Overall preformance Score64/100
Installation Manager Success Stats:
Reports Issued By 5185/6608 Users
Success Reported By 3955/5185 Users
Driver Download Score99/100
Driver Installation Score89/100
Overall preformance Score82/100
1. Direct DownloadSelect your OS and press "Download".
This option requires basic OS understanding.
Select Your Operating System, download zipped files, and then proceed to
manually install them.
Recommended if Rca Drc288su is the only driver on your PC you wish to update.
2. Driver Installation Manager
This option requires no OS understanding.
Automatically scans your PC for the specific required version of Rca Drc288su + all other outdated drivers, and installs them all at once.
After downloading and installing Rca Drc288su, or the driver installation manager, take a few minutes to send us a report:
* Only registered users can upload a report.
Don't have a password?
Please register, and get one.


text:
Recent Stories
Nebraska No. 1 in latest NTCA Coaches pollFebruary 7, 2017 3:38 ET
Nebraska comes in at No. 1 in latest NTCA Coaches poll.
Red Wolves voted No. 1 in November pollDecember 1, 2016 11:03 ET
WHITEWATER, Wis. ---The Red Wolves of Arkansas State received 26-1st place votes to put them on top of the first official NTCA (National Tenpin Coaches Association) Poll of the 2016-17 NCAA Bowling Season. Arka...
Changes to oil patterns approvedAugust 4, 2016 3:37 ET
The NCAA Playing Rules Oversight Panel on July 29 approved a change to the parameters for oil ratio application for the 2016-17 bowling season.
Oil pattern changes proposedJune 21, 2016 4:21 ET
The NCAA Women's Bowling Committee proposed to change the parameters for oil ratio application for the 2016-17 season.
SFA wins bowling championshipApril 16, 2016 11:15 ET
NORTH BRUNSWICK, N.J. -- After playing this past season as the defending national runner-ups, Stephen F. Austin will play its next as the defending national champions.
- Advertisement
Top Headlines
- MBKOSU cruises to upset over No. 16 Badgers
- MHKYNo. 5 UML takes top 15 HEA win vs. BC
- SOFTVols knock off defending champion OU
- WHKYDesbiens' journey to becoming elite goalie
- WBKSenior duo leads UK past No. 3 MSU in OT
- MBKWATCH: Cincy's one-handed alley-oop
- MBKKU turns focus from Big 12 to national title
- MHKYNick Schilkey has OSU on cusp NCAA tournament
- NC Bowling ChampionshipApril 13-15, 2017River Center Baton RougeBaton Rouge, Louisiana


text:
Be Employed today! Boost Your Pocket with Extra Money.
Published Date: Dec 1, 2016Contact Number: 07585040404
Category: Jobs » Part-time Jobs
Uttar Pradesh » Moradabad
Experience: 0 Years
Salary: 15000 Rs/Month
Qualification: 12th pass
Role : Employee
Key skills: Online jobs , Work From Home Jobs , Work at Home J
Posted by: Company
Job location: At homw
For more visit- http://adpostjob4u.com
E-mail us- email@example.com
Contact mobile- 075 85 04 04 04 , 081 45 04 04 04*By-GUY0652SP-01-12-16
Buy YouTube views
You can increase viewership to your YouTube videos and promote your channel visibility in YouTube. Earn more money from YouTube. Cost effective plans at Clicxa will help you increase the number of views your videos get in YouTube. You can attract views from targeted audience. For more details...Sep 8, 2016
CYBER EXPO ISO Certified Company needs 540 online workers
Are you Unemployed? Did you have passion to work online for extra income? Join Today in CYBER EXPO the most reputed online jobs provider company in India. Work any time like a boss. Get daily work daily payment for your works into your bank account. 540 of vacancy are waiting for you. Students,...Dec 15, 2016
Be Employed today! Boost Your Pocket with Extra Money.
Apply in CYBER EXPO (An ISO 9001: 2008 Certified) an award winning company on Online Part time jobs. 200 Jobs Vacancy in your city. Earn up to 10,000 per month while sitting at home. Just work for 2 or 3 hours and lets your free time earn for you. Join today in ad posting jobs, form filling jobs,...Dec 7, 2016
Posted By: Shubham
Contact No: 07585040404
Request New Code
Enter above verification code in provided textbox.


text:
About Matthews.Tech:
Thank you for visiting my blog, my name is Matthew and I am the sole owner of Matthews.Tech. I have a great interest in technology and development, this is expressed within my blog posts and I tend to feature content that provides users with information and development skills. I truly believe in respect, opportunity and support for all people who require it.
I have a great interest with servers and this is my focus of one of my job roles, when I get spare time I publish articles about a various amount of technology.
I am currently a student and in my spare time I try support others to setup various things from computers, servers to networks. Technology is my life and I can't get enough of it! Most, of the articles I write are currently funded by the spare change I have for the benefit of my readers. Those who find the time to read the articles I write and take something away from them are the most important people to me, I am hopeful that you are one of those people.
I like to believe I am a very friendly, open and approachable person. Please do not hesitate to email myself at info [at] Matthews.Tech and I shall respond as soon as possible.
If you are a company who is interested in sponsorship – I am approachable and would be happy to deal with your request, I have worked with a variety of companies and would be more than happy to work with any company that has fantastic morales!
Thank you for your time.
Important Information:
All mail is handled by the domain YNA.ME.UK – All email responses and emails sent from Matthews.Tech will be from this domain.
Matthews.Tech is empowered by love and passion of all forms and variations of technology!


text:
Rep. Kyrsten Sinema will join state lawmakers from across the United States in the coming months to help President Obama reshape the nation's health care policy and reform a system that politicians from both parties say is broken. The Phoenix ...Read More »
Reform bill absent from Senate's health committee hearing
The Senate Healthcare and Medial Liability Reform Committee met June 10 to consider bills for the first time since the start of the legislative session almost five months ago. Committee members heard measures that would automatically enroll KidsCare applicants in ...Read More »
Bill aims to include insurance firms in corporate tax credit program, repeal sunset
The Senate Appropriations Committee approved legislation June 9 to expand the corporate income tax credit to include insurance companies. The panel voted, 7-4, to advance the bill, which also aims to repeal a sunset provision for the corporate tax credit ...Read More »
Brewer appoints Pima Superior Court judge
Gov. Jan Brewer on June 10 announced the appointment of assistant U.S. attorney Richard Gordon to the Pima County Superior Court. Gordon had been with the U.S. Attorney's Office since 1998. Prior to his time as an assistant U.S. attorney, ...Read More »
Burns: Tentative agreement reached on tax increase
Legislative leaders and Gov. Jan Brewer have reached a tentative agreement to move forward with a one-cent sales tax increase as part of the budget, a top Republican said June 10. "There is basically a tentative agreement to go forward ...Read More »
With floodgates opened, Senate begins hearing regular bills
The Senate began hearing scores of bills June 8 following Senate President Burns' decision to shift strategy and open the floodgates for regular measures. Burns assigned hundreds of bills to committees last week after the Legislature approved a budget packet ...Read More »
Senate panel advances guns-in-restaurants bill
Restaurant, liquor lobbies soften stance on guns in restaurantsRead More »
Flake honored posthumously by colleagues
A bust of Sen. Jake Flake was unveiled on the Senate floor June 8. The clay bust was sculpted by former Sen. Rusty Bowers. A permanent bronze bust will be put on display in the Senate, House or old Capitol. ...Read More »
Brewer and 'stakeholders' pick apart Legislature's budget
Lawmakers fire back, from both sides of the political aisleRead More »
Arizona teachers recalled after April layoffs
School districts throughout Arizona have started recalling laid-off teachers amid a clearer budget picture and the retirement of some instructors. Districts issued reduction-in-force notices to about 7,000 teachers on April 15, according to the Arizona Education Association. Districts had to ...Read More »


text:
With Instructables you can share what you make with the world, and tap into an ever-growing community of creative experts.
Tell us about yourself!
DIY: Leather ChokerView Instructable »
DIY: RIpped JeansView Instructable »
Join 2 million + to receive instant DIY inspiration in your inbox.
© 2016 Autodesk, Inc.


text:
"Sleeping" Big Toe
Posted by
Kim R.
on 8/29/02 at 13:18 (093889)
I have pf/heel spurs in my left foot. I am currently undergoing physical therapy with stretching, ultrasound and iontophoresis (spelling?) with dexamethasone. I also have custom orthotics, sleep in a night-splint and ice 2 to 3 times daily. I have noticed that my big toe feels like it is asleep. Can you tell me what is causing this? Thank you.


text:
Recommended to support proper immune system, circulatory functions and skin health.
Give 2 capsules daily, per 10 lbs of body weight for 7-10 days. Then give 1 capsule, per 10 lbs of body weight, daily.
If giving more than one capsule, divide between AM and PM.
Safe use in pregnant animals or animals intended for breeding has not been proven.
If animal's condition worsens or does not improve, stop product administration and consult your veterinarian.
For animal use only.
Keep out of the reach of children and other animals. In case of accidental overdose, contact a health professional immediately.
Store in a cool, dry place.
|Active Ingredient Per Capsule:
|Grape Seed Extract (Vitis vinifera)
Standardized to yield 95% (9.5 mg) proanthocyanidins (PCO's) per capsule, which are potent antioxidants.
|10 mg
|Inactive Ingredients: Rice flour.


text:
- Hi there, welcome to Tribesmart. Log in to get started...
Goodbye Blanket Weed 32000gal (32 x 1000 Gallon Doses)
Guide price: £34
Last updated on 26th May 2013
Tags: nishikoi
Goodbye Blanket Weed 32000gal (32 x 1000 Gallon Doses)
Goodbye Blanket Weed. A worldwide patented natural blanket weed treatment that combines the powers of bacteria, enzymes and activated barley straw, packed into water-soluble dosing sachets. This pack will treat 1000 gallons with 32 doses (Multiple sachets can be used for larger ponds) Each Sachet treats 1000 gallons of pond water for 1 week Contains 32 x 25g sachets Manufacturer : NishiKoi Barcode : 5022459105100
Login or Register to add this to your wish list or favourites.


text:
Friday Sports Roundup
Written by Bwog Staff
February 06, 20092:50 pm 2 Comments
Men's Basketball: The men's basketball team had one of its most successful weekends of the season, sweeping Yale and Brown on consecutive nights at home. Against Yale, Jason Miller's 16 points and 10 rebounds led the Lions' comeback from a nine point halftime deficit to win 53-42, while against Brown the team shot 52% in the second half to pull away and win 67-60. Another piece of good news for the Lions was the return of guard Pat Foley, who scored 12 and 10 points in the two games. This weekend, the men's team hits the road to play at Penn on Friday night and at Princeton on Saturday. Both games can be heard at 7 p.m. on WKCR and 970AM.
Women's Basketball: The women's team split their two games, falling 63-61 to Yale on Friday, before bouncing back to beat Brown 76-51. Against Yale, forward Judie Lomax had 14 points and 18 rebounds, but the Lions were unable to pull out a game that was tied 13 times. The night after against Brown, guard Sara Yee scored 20 points, and Lomax again added 18 points and 15 rebounds, as the Lions romped to 25 point victory. This weekend, the team comes back home for games against Penn tonight and Princeton tomorrow night, both at 7 p.m. in the Levien Gym.
Swimming & Diving: The men's team beat Brown 186-112 last weekend, before facing off against Navy earlier this afternoon (no result in yet). The women's team joined in the sweep over Brown, 157-143, to improve to 4-1 against Ivy League foes, and they face Princeton tomorrow at noon in the Uris Pool.
Wrestling: After a tough loss at Bucknell last Sunday, the Lions face off against #3-ranked Cornell at home on Sunday (12 p.m. in the University Gym)
Fencing: After a weekend off, the fencing team hosts the first half of the Ivy League Fencing Championships this Sunday, starting at 11 a.m. in the Levien Gym.
Track & Field: This weekend, the track team competes in the University of Virginia Invitational, held at the NYC Armory.
Tags: Sports... on Bwog!


text:
Request Form
Thank you for your interest in our Icon Woven Shirt. Please complete your details below and click the 'Request Quotation' button at the bottom of the page. A customer service consultant will contact you about the Icon Woven Shirt with a quotation.
Icon Woven Shirt
Short Sleeve; Polycotton; Reinforced top stitching; Engraved matching buttons
R 265.52each


text:
BotCon wrote:BotCon 2012 presents... BEE IN THE CITY 2! The Script reading sequel, 4 years in the making!
Seibertron.com - The Ultimate Transformers Fansite
BotCon wrote:BotCon 2012 presents... BEE IN THE CITY 2! The Script reading sequel, 4 years in the making!
SlyTF1 wrote:I miss Animated.
Erailea wrote:SlyTF1 wrote:I miss Animated.
Shadowman wrote:This is Sabrblade we're talking about. His ability to store trivial information about TV shows is downright superhuman.
Caelus wrote:My wife pointed out something interesting about the prehistoric Predacons. I said that everyone was complaining because transforming for them mostly consisted of them just standing up-right. She essentially said, 'So? That's what our ancestors did.'
Return to Transformers General Discussion
Registered users: Alpha Weltall, Bing [Bot], bodrock, carytheone, chuckdawg1999, Cobotron, D-Maximus_Prime, ebo716, Exabot [Bot], GalvatronG1, Google [Bot], Google Adsense [Bot], GotBot, Hellscream9999, JelZe GoldRabbit, kirbenvost, Majestic-12 [Bot], Sigma Magnus, SlyTF1, steals_your_goats, SureShot18, WreckerJack, Yahoo [Bot]


text: http://www.abpnews.com/www/1338.article Patterson's defense of sermon censorship contradicts his own actions, critics say By Robert Marus and Greg Warner Published: September 1, 2006 ARLINGTON, Texas (ABP) -- Paige Patterson, president of the Southern Baptist Convention's largest seminary, censored a recent chapel sermon by a seminary trustee because it criticized a "sister" SBC institution. Yet in 2003 Patterson himself circulated a lengthy report by one of his professors that criticized the same agency. Dwight McKissic, a graduate and newly appointed trustee of Southwestern Baptist Theological Seminary, delivered the Aug. 29 morning chapel sermon at the Fort Worth school, where Patterson is president. McKissic, pastor of Cornerstone Baptist Church in nearby Arlington, criticized a controversial policy guideline of the International Mission Board that bans the appointment of missionaries who practice speaking in a "private prayer language." With Patterson seated onstage with him, McKissic recounted how, as a Southwestern student in 1981, he had an experience of speaking in a "private prayer language" that he believes was evidence of the Holy Spirit helping him communicate with God. McKissic, one of Southern Baptists' most prominent African-American leaders, said he has continued to have such experiences, which many theologians say is a private version of glossolalia, or speaking in tongues. After the service, in a break from stated practice, Patterson ordered that a recording of McKissic's sermon not be placed on Southwestern's website. Later in the day, school officials released a statement saying they made the decision because McKissic had criticized actions by a sister SBC institution and because seminary leaders "reserve the right not to disseminate openly views which we fear may be harmful to the churches." But three years ago, Patterson -- then president of Southeastern Baptist Theological Seminary in North Carolina -- distributed a "white paper" by Southeastern professor Keith Eitel that criticized the IMB and its president, Jerry Rankin, on a number of mission practices. Eitel's report and Patterson's cover letter, which was written on seminary letterhead, were sent by Patterson to all IMB trustees. Rankin has been the target of criticism from some of his own trustees, in part because he has acknowledged using a private prayer language. According to Rankin's defenders, a group of trustees is committed to forcing the long-time president out. In an open letter Aug. 30, McKissic, said he respects the seminary's decision to remove the sermon but regrets it nonetheless. He also implied Patterson endorsed tongues-speaking generally. McKissic said while Patterson's rationale for banning the sermon is "fair and affirming of all parties involved," he nevertheless believes it is "inconsistent with views attributed to you, views you've written, and [the views of] other outstanding Baptist scholars, theologians, and preachers." Southwestern Seminary officials, contacted for comment on McKissic's letter, did not respond. They did, however, make recordings of the sermon available for purchase directly from the seminary. Meanwhile, Southern Baptist bloggers said Patterson's reason for removing McKissic's sermon -- because it was critical of another agency -- was hypocritical. "If SWBTS is governed by such a principle, which would indeed be a good one, then why did Dr. Patterson, as president of SEBTS, circulate to the IMB board of trustees Dr. Keith Eitel's now infamous white paper called, Vision Assessment?" wrote Oklahoma pastor Art Rogers, who runs the 12 Witnesses blog (twelvewitnesses.blogspot.com). "You may recall…that this paper undermines Dr. Rankin and the overall vision of the IMB as it currently stands," Rogers said. "Talk about a violation of this policy!" Rogers said McKissic's sermon had "set off the political equivalent of a nuclear device" in Southern Baptist life. McKissic said the IMB's "public policy" on private prayer language warrants public discussion, which was the purpose of his sermon. He added the policy guideline "is in direct contradiction to what many noted Baptist scholars and preachers believe about the practice of a private prayer language. My statement was designed to cause the students to critically think about whether or not the IMB policy lines up with Scripture, not to criticize the IMB." He continued: "Because I said nothing during my message that contradicted the Bible or the 2000 Baptist Faith & Message [the SBC's doctrinal statement], I fail to see how my comments are viewed as outside of the Baptist mainstream. I do believe that banning the free distribution of my message on the school website is a form of unnecessary censorship that is most unusual considering the fact, again, that many Baptist scholars and leaders…have expressed views similar to mine." McKissic cited Baptist preachers and theologians -- evangelist Billy Graham, IMB president Rankin, and current SBC president Frank Page -- as defending the practice. He also offered further criticism of the IMB decision to ban new missionaries who practice a private prayer language. That ban has proven controversial within the denomination. Although Southwestern's faculty and trustees may reject private prayer language, McKissis wrote, "the leading evangelical African-American churches in America, including black Southern Baptists, would affirm the practice of a private prayer language by those who are so gifted by the Holy Spirit," McKissic said. "They would certainly not invoke a policy denying freedom of a gifted person to practice a private prayer language." McKissic, a new Southwestern trustee, has served as president of the pastors' conference of the conservative Southern Baptists of Texas Convention. He has also been at the forefront of efforts, on both state and national levels, to pass laws banning gay marriage. In an Aug. 29 interview with Associated Baptist Press, McKissic said he didn't know his sermon would cause such a stir, and he didn't believe Patterson had a problem with him or his view of tongues. "He has not in any way indicated that he has issues with what I have to say," he said. He noted that he had lunch with Patterson and his wife, Dorothy, following the chapel service. "I love Dr. Patterson, Dr. Patterson loves me, we had rich fellowship today," he said. "If they had a problem with it [the sermon], they didn't utter it to me at all.