text:
*Originally posted on April 3, 2008
IŌĆÖm sitting here at my desk staring at my screen, lost. For the first time in what feels like years I have nothing to do but sit and stare at the screen and wonder how I got here.
ItŌĆÖs odd, you know, being here, in this unfamiliar place. There are a number of things I could do with my time. I could search for some new music on itunes. Hard to find good tunes, the kind you just canŌĆÖt stop listening to. I could go outside and stare at the house IŌĆÖm having built, but itŌĆÖs raining and I would probably be the only one there, feet in the mud, wondering why itŌĆÖs not done, why the chimney looks crooked, why the front door is swinging in the wind.
I could listen to One Republic or Muse and write a blog. I choose Muse and decide to write the blog. But neither change the fact that IŌĆÖm sitting here staring at the screen, lost.
Eighteen months ago I began work on the first of a series of Young Adult novels that I agreed to write two at a time so that all six could be published in the space of one year. The Lost Books series, an extension of the Books of History Chronicles.
I must have been smoking the Christian equivalent of crack that day. As it turns out, writing Young Adult fiction is no easier than writing Adult fiction. My plots always become intense and demanding, and I, like my readers, crave my fantasy strong enough to make my head spin before I reach the bottom.
After writing Chosen, I suspected that I was up against a mountain that could not be climbed at least not by me. All of my novels are due to the publisher 1 year before they are published and immediately following Chosen I was to write Adam.
Adam kicked me in the gut like a panicked horse kicks its well intentioned trainer in the gut. Read it and you will understand. This is a novel for every man woman and child who dares wade through some fright to learn truth. And if your neighbor says they wonŌĆÖt read scary novels, tell them itŌĆÖs okay to read this one because if they donŌĆÖt their house might burn to the ground.
I turned Adam in and retreated to the South Pacific to write Infidel and Renegade. Infidel and Renegade were like a dance on the beach with a roaring bonfire at midnight. Magic came out of the smoke and swept me away to the a land far away.
Upon my return I took a day to search for new music and dove into Kiss, a book that a new author named Erin Healy and I are co-authoring for a 2009 release. While writing Kiss I dove into Chaos and approached the Publisher to express my concern that writing six YA novels was simply to ambitious considering the other stories I was dying to write, namely Sinner and Angel. The six book series became a four books series, with two more being moved into 2009.
Nine months ago (half way through my eighteen month sago) I moved to Austin, hunkered down amongst a pile of my landlordŌĆÖs books in a furnished rental, and coaxed the climax out of Chaos.
Chaos was a special journey for me because it answered a slew of questions the are circling around the Books of Histories and in particular Showdown. It also laid the groundwork for a novel I am desperate to tackle now but must wait a couple years until other stories in my head can get out of the way.
Satisfied with the completion of the four Young Adult books, Chosen, Infidel, Renegade and Chaos, and thrilled with Kiss, the book with Erin Healy, I came up for air, noticed that I had moved to a city in which I literally knew no one, and dove back down into the world of Sinner.
Sinner. What can I say. It was everything I hoped it would be. It made me weep, it made me dance, it made want run around the streets, throwing out copies for whoever would honor me by reading a few sentences. This is it! This is the one IŌĆÖve been trying to write my whole life! Dear God let me just tell them what happens and get it over with!
Alas, my publisher would have my head, which, along with my hands, I need.
My wife and I celebrated the writing of Sinner wildly.
Then it was back into the dungeon. Back into a hole in the ground with a killer called Bone Man who is is obsessed with finding the perfect daughter. This is a book IŌĆÖve had on my mind for five years and it ran out of me in long sittings. When the women he abducts fail to meet his expectations, Bone Man kills them by breaking every bone in their body without breaking their skin. ItŌĆÖs a very spiritual novel about a fatherŌĆÖs love for his daughter. I wish I could give it way. Dear God let me just tell them! This is it, this is the one IŌĆÖve been trying to write!
Adam came out April 1st and IŌĆÖm thrilled to see that some people are buying it. In fact, I went into a B&N and found it on the front table. And a stack of Skin two tables over. When a woman approached me and asked if I knew anything decent, I hesitated then sheepishly pointed to Adam. That oneŌĆÖs pretty good. She snatched it up and opened the back to see my photo. It took her a few seconds to connect the dots, a common reaction readers have to many of my stories.
Now the reviews on Adam are coming in and IŌĆÖve scoured the internet to either pump my fist with the readers or scoff at their ignorance, depending on how enthusiastic theyŌĆÖve been in their review.
But after a couple days IŌĆÖm done with that and I sit here in front of my computer and I am taking a long two month break, one month of it over seas, before returning to the dungeon and entering the world of GREEN.
ThatŌĆÖs the one. ThatŌĆÖs the one IŌĆÖve been trying to write my whole life. I wish I could tell you what I have planned for Green. There will be some fist pumping and wild, wild celebration on that one, I can tell you.
But for nowŌĆ" For now I feel lost. Too exhausted to write. I need to give my head a rest. I need to find some music. I need to travel the world. I need to laugh with my children all day long. I need to seduce my wife.
I need to see the people who make my world go around, those retailers and readers and co-laborers in this task of unfolding the mysteries of God through story. I need to recharge for a few days at least. Maybe even a week. Or two.
And then, on June 7th, I will go to the GATHERING in Nashville where my comrades in the Circle will join me in the dungeon and I will join them on the surface and together we will celebrate…


text:
Terrine de Campagne
|2 Clove (10 gm), crushed
|Bacon (streaky) rashers
|1 Pound (500 Grams)
|Fresh white breadcrumbs
|4 Ounce (125 Grams)
|Dry red wine
|1⁄4 Pint (150 Milliliter)
|Pork belly
|12 Ounce, minced (350 Grams)
|Pork livers
|12 Ounce, chopped (350 Grams)
|Chicken livers
|1 Pound, chopped (500 Grams)
|Chopped thyme
|1 Teaspoon
|Chopped sage
|1 Teaspoon
|Chopped parsley
|1 Tablespoon
|Grated nutmeg
|1 Teaspoon
|Parsley sprigs
|3 (For Garnish)
Remove the rind from the bacon rashers and use half to line the base and sides of a large terrine or loaf tin, stretching them to fit if necessary.
Chop the rest of the bacon and mix with the remaining ingredients, adding nutmeg, salt and pepper to taste.
Turn into the prepared dish, press down firmly and cover with buttered greaseproof paper and foil.
Place in a bain-marie and bake in a preheated moderate oven, 160°C (325°F), Gas Mark 3, for 2 to 2 1/2 hours.
Place a weight on top of the terrine and leave to cool, then chill.
Turn out and garnish with parsley.
Serve sliced, with melba toast.
Rate It
Nutrition Rank
Nutrition Facts
Serving size: Complete recipe
Calories 4328 Calories from Fat 2121
% Daily Value*
Total Fat 236 g362.7%
Saturated Fat 102.4 g512.1%
Trans Fat 0.3 g
Cholesterol 3513.1 mg1171%
Sodium 5557.6 mg231.6%
Total Carbohydrates 89 g29.6%
Dietary Fiber 5.3 g21.3%
Sugars 8.6 g
Protein 409 g818.8%
Vitamin A 2528.4% Vitamin C 344.2%
Calcium 44.1% Iron 731.2%
*Based on a 2000 Calorie diet

subset: commoncrawl


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text: We had seen Dennis's in a guide book and decided to visit on a Sunday. We arrived soon after 12 which was just as well, as within an hour the place was full and buzzing. The food was excellent, the ambience amazing and the musicians, who played for over an hour without a break, were of a ridiculously high standard.... More


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To the Editor.—
Recently we published an article citing our initial experience with asanguineous hypothermic total body perfusion (total body washout or TBW) in the resuscitation of a patient dying of stage IV hepatic coma.1 The patient went on to die of Pseudomonas pneumonia which was present prior to the performance of the TBW. That partial success served to teach us to be more selective of future candidates and to make certain adjustments in our perfusate. These were done in our latest attempt to use the procedure in the care of a young airman dying of acute Australia antigen hepatitis.The airman had been ill and hospitalized for four weeks prior to transfer to our hospital. In the fifth week of his illness and in spite of intensive therapy with bowel antisepsis, steroids, and modified diet, he lapsed into a deepening coma. When received at our hospital, the patient
Klebanoff G. Total Body Perfusion. JAMA. 1972;220(11):1495. doi:10.1001/jama.1972.03200110073022
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The Shawl
[CD-Audio/MP3 Edition]
By (author) Cynthia Ozick
Narrator Yelena Shmulenson
Format: CD-Audio
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Shawl by Cynthia Ozick
Book DescriptionTwo award-winning works of fiction by one of America's finest writers, together in one collection. In "The Shawl," a woman named Rosa Lublin watches a concentration camp guard murder her daughter. In "Rosa," that same woman appears 30 years later, "a mad woman and a scavenger" in a Miami hotel. She has no life in the present because her past will never end. In both stories, there is a shawl-a shawl that can sustain a starving child, inadvertently destroy her, or magically conjure her back to life. Both stories were originally published in the New Yorker in the 1980s; each was included in the annual Best American Short Stories and awarded First Prize in the annual O. Henry Prize Stories collection. Each succeeds in imagining the unimaginable: the horror of the Holocaust and the unfillable emptiness of its aftermath. Fiercely immediate, complex, and unforgettable, each is a masterwork by a writer the New York Times hailed as "the most accomplished and graceful literary stylist of our time."
Buy Shawl book by Cynthia Ozick from Australia's Online Bookstore, Boomerang Books.
Book DetailsISBN: 9781598876840
(145mm x 131mm x 11mm)
Imprint: Highbridge Company
Publisher: Highbridge Company
Publish Date: 12-Nov-2008
Country of Publication: United States
Other Editions...
Books By Author Cynthia Ozick
Letters of Intent, Hardback (April 2017)
A selection of essays by the acclaimed and beloved writer Cynthia Ozick, collected by David Miller.
Reimagined, Hardback (September 2016)
Wide ranging appeal across the realm of Judaic interest - from fans of artists such as Ben Shahn to illustrators like David Levine. A must-have for collectors of both art and written works of Judaica.
Critics, Monsters, Fanatics, and Other Literary Essays, Hardback (July 2016)
A collection of new and previously published essays on contemporary literary culture, authors, and critics by the acclaimed writer and critic
Puttermesser Papers, Paperback (January 2014)» View all books by Cynthia Ozick
Overflowing with ideas, spiked with wit and humanity, The Puttermesser Papers is a tour de force by one of America's most visionary novelists
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Neural mechanisms of savant calendar calculating in autism: an MEG-study of few single cases.
Brain Cogn 2014 Oct;90():157-64
The impact of the metabotropic glutamate receptor and other gene family interaction networks on autism.
Nat Commun 2014 Jun;5():4074
Multimodal brain imaging in autism spectrum disorder and the promise of twin research.
Autism 2015 Jul;19(5):527-41
Relative immaturity and ADHD: findings from nationwide registers, parent- and self-reports.
J Child Psychol Psychiatry 2014 Aug;55(8):897-904
Cognitive behavior therapy-based psychoeducational groups for adults with ADHD and their significant others (PEGASUS): an open clinical feasibility trial.
Atten Defic Hyperact Disord 2015 Mar;7(1):89-99
Brain-expressed exons under purifying selection are enriched for de novo mutations in autism spectrum disorder.
Nat. Genet. 2014 Jul;46(7):742-7
The interdisciplinary quest for behavioral biomarkers pinpointing developmental disorders.
Dev Neurorehabil 2016 ;19(2):73-4
Is autism curable?
Dev Med Child Neurol 2014 Oct;56(10):927-31
Highlighting the first 5 months of life: General movements in infants later diagnosed with autism spectrum disorder or Rett syndrome.
Einspieler C, Sigafoos, Bartl-Pokorny KD, Landa R, Marschik PB, Bolte S.
Res Autism Spec Disord. 2014, 8(3):286-291
Convergence of genes and cellular pathways dysregulated in autism spectrum disorders.
Am. J. Hum. Genet. 2014 May;94(5):677-94
The Roots of Autism and ADHD Twin Study in Sweden (RATSS).
Twin Res Hum Genet 2014 Jun;17(3):164-76
[The diagnostic behavioural assessment for autism spectrum disorders (DiBAS)].
Psychiatr Prax 2015 Apr;42(3):140-6
Reduced predictable information in brain signals in autism spectrum disorder.
Front Neuroinform 2014 ;8():9
The power of words: is qualitative research as important as quantitative research in the study of autism?
Autism 2014 Feb;18(2):67-8
Common variants in genes of the postsynaptic FMRP signalling pathway are risk factors for autism spectrum disorders.
Hum. Genet. 2014 Jun;133(6):781-92
The added value of the combined use of the Autism Diagnostic Interview-Revised and the Autism Diagnostic Observation Schedule: diagnostic validity in a clinical Swedish sample of toddlers and young preschoolers.
Autism 2015 Feb;19(2):187-99
Explicit versus implicit social cognition testing in autism spectrum disorder.
Autism 2014 Aug;18(6):684-93
Classification of functioning and impairment: the development of ICF core sets for autism spectrum disorder.
Autism Res 2014 Feb;7(1):167-72
The missing link: delayed emotional development predicts challenging behavior in adults with intellectual disability.
J Autism Dev Disord 2014 Apr;44(4):786-800
The state of play of ASC-Inclusion: Integrated Internet-Based Environment for Social Inclusion of Children with Autism Spectrum Conditions.
Schuller B, Marchi E, Baron-Cohen S, O'Reilly H, Pigat D, Robinson P, Davies I, Golan O, Fridenson S, Tal S, Newman S, Meir N, Shillo R, Camurri A, Piana S, Stagliano A, Bölte S, Lundqvist D, Berggren S, Baranger A, Sullings N.
In Proceedings of IDGEI 2nd International Workshop 2014
Screening for substance use disorders in neurodevelopmental disorders: a clinical routine?
Eur Child Adolesc Psychiatry 2014 May;23(5):365-8
Neurobiologically based interventions for autism spectrum disorders-rationale and new directions.
Restor. Neurol. Neurosci. 2014 ;32(1):197-212
Brief report: "Quick and (not so) dirty" assessment of change in autism: cross-cultural reliability of the Developmental Disabilities CGAS and the OSU autism CGI.
J Autism Dev Disord 2014 Jul;44(7):1773-8
ASC-Inclusion: Interactive Emotion Games for Social Inclusion of Children with Autism Spectrum Conditions.
Schuller B, Marchi E, Baron-Cohen S, OReilly H, Robinson P, Davies I, Golan O, Friedenson S, Tal S, Newman S, Meir N, Shillo R, Camurri A, Piana S, Bölte S, Lundqvist D, Berggren S, Baranger A, Sullings N.
In Proceedings of IDGEI 1st international workshop 2013
Recognition Memory for High and Low Associative Stimuli in Autistic Individuals with Outstanding Memory Skill.
Neumann N, Braun C, Dubischar-Krivec AM, Bölte S.
Scand J Child Adolesc Psychiatry Psychol. 2013 1:43-50.
Attention deficit/hyperactivity disorders with co-existing substance use disorder is characterized by early antisocial behaviour and poor cognitive skills.
BMC Psychiatry 2013 Dec;13():336
Development of ICF Core Sets to standardize assessment of functioning and impairment in ADHD: the path ahead.
Eur Child Adolesc Psychiatry 2014 Dec;23(12):1139-48
Severe affective and behavioral dysregulation in youths is associated with a proinflammatory state.
Z Kinder Jugendpsychiatr Psychother 2013 Nov;41(6):393-9
Eye-tracking in basic research and clinical practise.
Bartl-Pokorny KD, Pokorny F, Bölte S, Langmann A, Falck-Ytter T, Wollin T, Einspleler C, Slagfoors J, Marschik PB.
Klin Neurophysiol. 2013 44(3):193-198
Eye tracking in early autism research.
J Neurodev Disord 2013 Sep;5(1):28
Emotional development in adults with autism and intellectual disabilities: a retrospective, clinical analysis.
PLoS ONE 2013 ;8(9):e74036
Open access, peer-reviewed, fast track processing, and high quality articles on all topics related to child and adolescent psychiatry and psychology.
Storebø OJ, Bölte S.
Scand J Child Adol Psychiatry Psychol. 2013;1:1-38
Face puzzle-two new video-based tasks for measuring explicit and implicit aspects of facial emotion recognition.
Front Psychol 2013 ;4():376
Lack of visual orienting to biological motion and audiovisual synchrony in 3-year-olds with autism.
PLoS ONE 2013 ;8(7):e68816
New interview and observation measures of the broader autism phenotype: impressions of interviewee measure.
J Autism Dev Disord 2013 Sep;43(9):2082-9
Infants at risk for autism: a European perspective on current status, challenges and opportunities.
Eur Child Adolesc Psychiatry 2013 Jun;22(6):341-8
Diagnosing autism in a clinical sample of adults with intellectual disabilities: how useful are the ADOS and the ADI-R?
Res Dev Disabil 2013 May;34(5):1642-55
Executive and visuo-motor function in adolescents and adults with autism spectrum disorder.
J Autism Dev Disord 2013 May;43(5):1222-35
Family history of suicide and exposure to interpersonal violence in childhood predict suicide in male suicide attempters.
J Affect Disord 2013 May;148(1):92-7
Relationships between years of education and gray matter volume, metabolism and functional connectivity in healthy elders.
Neuroimage 2013 Dec;83():450-7
Age effect on the default mode network, inner thoughts, and cognitive abilities.
Neurobiol. Aging 2013 Apr;34(4):1292-301
Visualization and analysis of eye movement data from children with typical and atypical development.
J Autism Dev Disord 2013 Oct;43(10):2249-58
The motor cortex is causally related to predictive eye movements during action observation.
Neuropsychologia 2013 Feb;51(3):488-92
Autism spectrum disorders (ASD).
Autism 2012 Nov;16(6):555-6
Individual common variants exert weak effects on the risk for autism spectrum disorders.
Hum. Mol. Genet. 2012 Nov;21(21):4781-92
Do symptoms of ADHD at ages 7 and 10 predict academic outcome at age 16 in the general population?
J Atten Disord 2014 Nov;18(8):635-45
Impaired gamma-band activity during perceptual organization in adults with autism spectrum disorders: evidence for dysfunctional network activity in frontal-posterior cortices.
J. Neurosci. 2012 Jul;32(28):9563-73
Brief Report: the Social Responsiveness Scale for Adults (SRS-A): initial results in a German cohort.
J Autism Dev Disord 2012 Sep;42(9):1998-9
Valence scaling of dynamic facial expressions is altered in high-functioning subjects with autism spectrum disorders: an fMRI study.
J Autism Dev Disord 2012 Jun;42(6):1011-24
A close eye on the eagle-eyed visual acuity hypothesis of autism.
J Autism Dev Disord 2012 May;42(5):726-33
The efficacy of intensive behavioral intervention for children with autism: a matter of allegiance?
J Autism Dev Disord 2012 Jan;42(1):139-40
Long-term functional outcome in adult prison inmates with ADHD receiving OROS-methylphenidate.
Eur Arch Psychiatry Clin Neurosci 2012 Dec;262(8):705-24
Prenatal dexamethasone treatment of children at risk for congenital adrenal hyperplasia: the Swedish experience and standpoint.
J. Clin. Endocrinol. Metab. 2012 Jun;97(6):1881-3
Personality traits in attempted and completed suicide.
Eur. Psychiatry 2012 Oct;27(7):536-41
Humans Anticipate the Goal of other People's Point-Light Actions.
Front Psychol 2012 ;3():120
Gaze performance in children with autism spectrum disorder when observing communicative actions.
J Autism Dev Disord 2012 Oct;42(10):2236-45
Predicting other people's action goals with low-level motor information.
J. Neurophysiol. 2012 Jun;107(11):2923-5
Longitudinal high-risk sibling studies of autism spectrum disorder.
Microb. Ecol. Health Dis. 2012 ;23():
Autism spectrum disorders in the Stockholm Youth Cohort: design, prevalence and validity.
PLoS ONE 2012 ;7(7):e41280
Social and individual aspects of classroom learning in students with Autism Spectrum Disorder: an action research pilot study on assessment.
Åsberg J, Zander U, Zander E, Dahlgren Sandberg A.
Eur J Spec Needs Edu. 2012. 27(1):115-127
Gender role behaviour in prenatally dexamethasone-treated children at risk for congenital adrenal hyperplasia--a pilot study.
Acta Paediatr. 2011 Sep;100(9):e112-9
The Child and Adolescent Twin Study in Sweden (CATSS).
Twin Res Hum Genet 2011 Dec;14(6):495-508
Electromagnetic evidence of altered visual processing in autism.
Neuropsychologia 2011 Sep;49(11):3011-7
Neurofeedback in autism spectrum disorders.
Dev Med Child Neurol 2011 Nov;53(11):986-93
[Psychobiosocial interventions for autism].
Nervenarzt 2011 May;82(5):590-6
Sex differences in cognitive domains and their clinical correlates in higher-functioning autism spectrum disorders.
Autism 2011 Jul;15(4):497-511
[Personality and social responsiveness in autism spectrum disorders and attention deficit/hyperactivity disorder].
Z Kinder Jugendpsychiatr Psychother 2011 Mar;39(2):133-41
[Neuropsychological models of autism spectrum disorders - behavioral evidence and functional imaging].
Z Kinder Jugendpsychiatr Psychother 2011 Mar;39(2):79-90
Early developmental regression in autism spectrum disorder: evidence from an international multiplex sample.
J Autism Dev Disord 2011 Mar;41(3):332-40
Autistic traits and autism spectrum disorders: the clinical validity of two measures presuming a continuum of social communication skills.
J Autism Dev Disord 2011 Jan;41(1):66-72
Reduced ADHD symptoms in adults with ADHD after structured skills training group: results from a randomized controlled trial.
Behav Res Ther 2011 Mar;49(3):175-85
Long-term outcome of prenatal dexamethasone treatment of 21-hydroxylase deficiency.
Endocr Dev 2011 ;20():96-105
Deficient cardiovascular stress reactivity predicts poor executive functions in adults with attention-deficit/hyperactivity disorder.
J Clin Exp Neuropsychol 2011 Jan;33(1):63-73
The default mode network in healthy aging and Alzheimer's disease.
Int J Alzheimers Dis 2011 ;2011():535816
Which SPM method should be used to extract hippocampal measures in early Alzheimer's disease?
J Neuroimaging 2011 Oct;21(4):310-6
How special is social looking in ASD: a review.
Prog. Brain Res. 2011 ;189():209-22
Human infants orient to biological motion rather than audiovisual synchrony.
Neuropsychologia 2011 Jun;49(7):2131-5
ADHD, en kontroversiell diagnos.
Bölte S.
BestPractice Psykiatri/Neurologi. 2011 11:5-7
A genome-wide scan for common alleles affecting risk for autism.
Hum. Mol. Genet. 2010 Oct;19(20):4072-82
The mind of the mnemonists: an MEG and neuropsychological study of autistic memory savants.
Behav. Brain Res. 2010 Dec;215(1):114-21
Functional impact of global rare copy number variation in autism spectrum disorders.
Nature 2010 Jul;466(7304):368-72
Linkage and candidate gene studies of autism spectrum disorders in European populations.
Eur. J. Hum. Genet. 2010 Sep;18(9):1013-9
Bipolar disorder in children and adolescents in Germany: national trends in the rates of inpatients, 2000-2007.
Bipolar Disord 2010 Mar;12(2):155-63
[Does the Fragmented Images Test measure locally oriented visual processing in autism spectrum disorders?].
Z Kinder Jugendpsychiatr Psychother 2010 Mar;38(2):103-10
Face scanning distinguishes social from communication impairments in autism.
Dev Sci 2010 Nov;13(6):864-75
Young children with autism spectrum disorder use predictive eye movements in action observation.
Biol. Lett. 2010 Jun;6(3):375-8
Is Preference for Geometry a Valid Early Sign of Autism Spectrum Disorder?
Falck-Ytter T, Bölte S.
Arch Gen Psychiatry, 2010 Dec 16. (peer reviewed letter)
Severe affective and behavioral dysregulation in youth is associated with increased serum TSH.
J Affect Disord 2010 Feb;121(1-2):184-8


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This is our dog, Raafy, he's a Maltese x Shih Tzu and such a lovely little fellow.
This is our dog, Raafy, he's a Maltese x Shih Tzu and such a lovely little fellow.
These are my girls, the black one I am not 100% what she is they said staffy x when I got her thinking she was just a pup I said yeah turns out she is fully grown! So we call her a chaffy (staffy x chihuahua) lol I have no idea what she is but adorable, her names shadow
And the white one is our boxer her name is sonar and she in compleatly deaf, her other senses are pretty bad too so she's very timid and was very under weight when I got her, but she's super energetic just needs some extra lovin!
Aww I love seeing all these beautiful animals. Here are our furry babies... 2 Devon Rex cats (dali and pablo) both 5 years old and are still the naughtiest things ever! And our newest addition a little Blenheim cavalier, Ruby! We pick her up this weekend and I am so excited!!
This is our dwarf plush lop bunny Bruce!
chameleon (01-06-2012)
These are the fish, names are bb, Nemo and sucker (the sucker fish is hiding) Nemo had a dodgy top fin lol
Sent from my MB526 using BubHub
ImageUploadedByBub Hub1337820772.255790.jpg
This Millie our one year old mastiff x ridgeback from RSPCA
ImageUploadedByBub Hub1337820800.303586.jpg
Gizmo who is 3 rescued from a cat shelter.
I have 2 cats.
Mason is and orange rescue cat and Coco is a chocolate burmese.
ImageUploadedByBub Hub1337821346.550090.jpg
Annabelle, she is a 9 year old pure bread chihuahua
She was my first baby.
ImageUploadedByBub Hub1337821420.626329.jpg
This is Toby, he is a Cavalier King Charles.
He is only 1
And is my husbands dog.
We recently had a staffordshire bull terrier named Buster pass away, he was 14 years old.
Annabelle (the chihuahua) really struggled when Buster died, so that's why Toby (cavalier) came along... Toby is a handful!! Lol
These are my two pups. Jade is a Labrador x and jasper is a husky x white shepherd.
We have roxy our 18 month old mini foxy , Bella our bull mastiff cross ridgeback she's approx 2 .5 yrs old and was rescued from the qld floods and Tinka she is 10 wks old
Pregnant for the first-time?
Not sure where to start? We can help!
Our Insider Programs for pregnancy first-timers will lead you step-by-step through the 14 Pregnancy Must Dos!


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ProMark Performer Series PSM10 Marimba Mallet
ProMark Performer Series PSM10 Marimba Mallet
The Performer Series marimba mallets are designed specifically to fit the needs of the most discerning player. Perfect for those solo pieces in which the player would like to use a graduated set of mallets.
- PSM10 mallets are soft, yarn-wrapped mallets, ideal for the lowest range on the instrument
- Length: 17" Head Size: 1.65 x 1.85"
- The high level of craftsmanship and tonal qualities throughout this line of mallets is ideal for the professional players and serious students and teachers
- Natural wood, unpolished handles for long lasting grip
- All ProMark drumsticks are designed and manufactured in the USA to the most stringent quality controls in the industry
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Kurt Busch wins Daytona 500 for his first victory in NASCAR's season-opener
Ryan Blaney finished second.
Ryan Blaney finished second.
The damage is discovered less than a week after similar vandalism in Missouri.
Walnut Lodge Yoga donated 10 weeks of free yoga to Sharon Fire Department's firefighters, who go twice a week.
The 29-year-old Kipnis hit .275 with 23 homers and 82 RBIs last season.
The Shenango Valley Mall held an active-shooter training session Sunday morning from 6-10 a.m.
Samsung recalled millions of Note 7 phones after dozens overheated and caught on fire.
The woman has been identified as Gabriel Ann Hinojosa, who had been reported missing Feb. 19.
Fitch senior Tim Kubacki also finished 4th in the 100 yard backstroke Saturday.
The YSU Men's and Women's Indoor Track and Field teams have a lead after Day 1 of the Horizon League Championships.
Police say 28 people were hurt in the accident that sent three people to the hospital.
Williams, a five-time All-Star, was waived this week by Dallas.
The case reaches the Supreme Court after it was upheld by North Carolina's highest court in a divided ruling.
Reed held off Austin Dillon and Kasey Kahne in a two-lap overtime shootout.
Around 75 people from western PA voiced their concerns about the future of health care outside of Mike Kelly's office.
The goal of the event was bring the community and government together.
The Cavaliers were 4-18 without James since he returned to Cleveland in 2014, including 0-3 this season.
Merritt allowed two runs and four hits in two innings.
Several men were recognized for bringing positive change to their community.
Some Trump supporters are calling for a boycott of the broadcast.
Ali Jr., 44, who confirmed his Muslim faith, was detained about two hours.
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Listen to free music by Diamond Youth
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UNM-G REI - Our History
The UNM Gallup Rural Entrepreneur Institute (REI) formally got underway in fall 2009 with generous funding support from the Johnson Scholarship Foundation of West Palm Beach, Florida and the state of New Mexico. REI was established in response to the increasing number of local entrepreneurs who, with needed support and resources, can take greater advantage of the opportunities available to them as small business owners.
REI relies on a host of volunteers from the greater Gallup area for consultation and advice in building up its resource capacity. With assistance from the REI Advisory Team (REIAT), numerous projects have been identified and accomplished. Among the notables have been the Entrepreneur Expo, Business Outlook Forum, Revised Entrepreneur Curriculum, and Business/Entrepreneur Scholarships.
The greater Gallup service area of REI encompasses 50 miles radius of land-base that include federal, state, counties, and tribal lands where 23 communities thrive and composed of nearly 70,000 population, mostly American Indians - mainly Navajo and the Pueblo of Zuni.


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Paul Ryan's PAC Gave To Mourdock's Campaign
A $5,000 contribution to the conservative's bid in June. Since his remarks about rape Tuesday night, Republicans — and the Romney-Ryan campaign — have backed away from the Senate candidate.
FEC filings reveal that Paul Ryan's Prosperity PAC made a payment of $5,000 on June 26 to Richard Mourdock, the Indiana Senate candidate under fire for comments Tuesday night that pregnancy from rape is "something God intended."
In response to a question in the Indiana debate about abortion in cases of rape and incest, Mourdock said in full: ''I struggled with it myself for a long time, but I came to realize that life is that gift from God. And, I think, even when life begins in that horrible situation of rape, that it is something that God intended to happen."
Since Tuesday night, Republicans affiliated with Mourdock have distanced themselves from the candidate's remark.
U.S. Rep. Mike Pence, the Republican candidate in Indiana's race for governor, said in a statement Wednesday morning, "I strongly disagree with the statement made by Richard Mourdock during last night's Senate debate. I urge him to apologize."
In a statement to the Associated Press Wednesday morning, Romney campaign spokeswoman Andrea Saul said Romney "disagrees with Richard Mourdock's comments, and they do not reflect his views."
The leadership PAC, still affiliated with the Vice Presidential nominee, has given contributions of similar amounts to Republican Senate campaigns this cycle such as North Dakota's Rick Berg and Nevada's Dean Heller.
3. The FEC filing:
Update: This post originally referred to Prosperity PAC as a SuperPAC. The committee is a Leadership PAC.
- Donald Trump said that his comments about Sweden were referring to a Fox News segment, not an actual incident in the country 🇸🇪🙃
- The CEO of Uber is investigating sexism and sexual harassment claims after a former employee said her reports were ignored.
- Geologists say they've discovered an eighth continent beneath New Zealand. "Zealandia" is 94% submerged underwater 🔎🌍
- The US ambassador to Somalia gave the country's new president a "Make Somalia Great Again" hat and the exchange was ~confusing~.


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Wednesday, October 7, 2015
Spotlight On...Colby Day
Hometown: Alamo, CA
Education: New York University, Department of Dramatic Writing
Favorite Credits: Felix & The Diligence which a high school in Vermont performed and it was the most magical experience of my life. It's a fishing adventure with mermaids and sea monsters and Nazi spies. Everything Flashes, a tour of your memories which I've developed and am still developing with so many folks (The In-Between People, Theater Reconstruction Ensemble, and Pipeline Theatre Company), and this video: The Greatest Play Ever.
Why theater?: It's magic. Sometimes with LITERAL magic. Great theater is the closest I think I get to a religious experience. Bad theater is the closest I get to hell. And as a writer, theater is definitely the most fun form. You're working with people, often smarter than you, and if you work with the right people, they're making your stuff WAY better the entire time. And then you get credit for it.
Tell us about Kitchen Sink Experiment(s): It's a kitchen sink show with a real kitchen sink. It explores what it is to feel observed, what it is to feel judged, and asks how the heck can we ever get comfortable in our own skin.
What inspired you to write Kitchen Sink Experiment(s)?: I wanted to challenge myself to write something hyper-hyper realistic and see what that would mean for an audience. It's a show you can kind of live in and reach out and touch, without being "immersive" in the ways I don't like. Nobody is going to force you to do anything, you can just observe and be taken care of. The seed of the idea came from a podcast I'd heard about a similar research project that had not gone well, and I thought "Oh, that's a play!"
What kind of theater speaks to you? What or who inspires you as an artist?: Honestly? Magic. It doesn't need to be real magic, but if you can do something that seems impossible onstage, I am sold. That can be big, like redefining a space, or it can be small, like taking me somewhere emotionally I did not expect. I like twists and turns.
If you could work with anyone you've yet to work with, who would it be?: I have to second pretty much ALL of Andrew's list. And would add probably Woodshed Collective into the mix.
What show have you recommended to your friends?: Go see Pipeline Theatre Company's The Gray Man. It's running right now and is beautiful and spooky and magic.
Who would play you in a movie about yourself and what would it be called?: I'd like it to be Ryan Gosling and it would be called "That Colby Sure is Sexy."
If you could go back in time and see any play or musical you missed, what would it be?: I'd love to go back and see the original failed run of Tennessee Williams' Camino Real. That show is such a mess in a way that I love and admire and would 100% want to see. Or Our Town? I'm a sucker for sentimental shows.
What's your biggest guilty pleasure?: Black & White Cookies. I will never not buy and eat one and I have strong opinions about each and every brand available in the NY metro area.
If you weren't working in theater, you would be _____?: A used car salesman.
What's up next?: I'm doing a workshop of my show [untitled time dilation play] in November and then am putting together a reading of Edgy Christmas Reboot, a dark, gritty re-telling of the Rankin & Bass Claymation Christmas specials.
For more on Colby, visit www.colbyday.com. For more on Kitchen Sink Experiment(s), visit www.crashboxtheater.org.
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Jurong BirdPark Singapore
- Posted Dec. 21, 2008 by Soo Chan Chiew in Nature. Viewed 2159 times
- This is a migrated legacy post. Image resolution is low. Info
1 There is 1 comment, add yours!
2008.12.24 Edited
ahhh..i see that you visited the bird park...and it seemed a sunny day..great day to go outdoors:)


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Packaging Sacks Market report 2016-2020 focuses on the major drivers and restraints for the key players. Packaging Sacks research report also provides granular analysis of the market share, segmentation, revenue forecasts and geographic regions of the market. The Packaging Sacks market research report is a professional and in-depth study on the current state of Packaging Sacks Industry.
Analysts forecast the global Packaging Sacks market to grow at a CAGR of 2.12% during the period 2016-2020.
Browse Detailed TOC, Tables, Figures, Charts and Companies Mentioned in Global Packaging Sacks market research report @ http://www.360marketupdates.com/global-high-barrier-packaging-film-market-2016-2020-10290167
The Packaging Sacks Market research report covers the present scenario and the growth prospects of the global Packaging Sacks industry for 2016-2020.
Packaging sacks are standardized flexible bulk bags used in the industrial packaging of mainly dry, lose, or granulated materials. They are used for protecting, storing, transporting, and handling of goods in large quantities from manufacturing centres to distribution centres, where they are packaged for customers. Packaging sacks are made of plastic, paper, or jute in different weights and strength parameters.
Key Vendors of Packaging Sacks Market:
• Global-Pak
• Hood Packaging
• LC Packaging
• Mondi
• Sonoco
And many more…
Packaging Sacks Market driver
• Demand from diverse sectors
• For a full, detailed list, view our report
Get Sample PDF of Packaging Sacks Market Report@
Packaging Sacks market report provides key statistics on the market status of the Packaging Sacks manufacturers and is a valuable source of guidance and direction for companies and individuals interested in the Packaging Sacks industry.
Packaging Sackss are used for different packaging applications in the food, healthcare, consumer goods, and other industries. These films are usually made of plastic as it is lightweight, non-corrosive, relatively cheaper than other materials, and can be molded into different shapes. The materials generally used in the manufacture of packaging films are polypropylene, polyamide, polyethylene, polyvinyl chloride, ethylene vinyl alcohol, and polyester.
Regions of Packaging Sacks market:
• Americas
• Europe
Packaging Sacks Market trend
• Increasing demand for flexible packaging
• For a full, detailed list, view our report
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Through the statistical analysis, the report depicts the global Packaging Sacks market including capacity, production, production value, cost/profit, supply/demand and import/export. The total market is further divided by company, by country, and by application/type for the competitive landscape analysis.
Key questions answered in Packaging Sacks market report:
· What will the market size be in 2020 and what will the growth rate be?
· What are the key market trends?
· What is driving this market?
· What are the challenges to market growth?
· Who are the key vendors in this market space?
· What are the market opportunities and threats faced by the key vendors?
· What are the strengths and weaknesses of the key vendors?
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The report then estimates 2016-2020 market development trends of Packaging Sacks market. Analysis of upstream raw materials, downstream demand, and current market dynamics is also carried out. In the end, the report makes some important proposals for a new project of Packaging Sacks market before evaluating its feasibility.
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"Annie Barrows accomplishes the almost impossible task of reflecting the world of second grader, creating the tension and drama of family and friendships in language that can be read easily by child who recently graduated from easy readers to early chapter books. " Lisa Von Drasek, Children's Librarian, Bank Street College of Education
Ivy and Bean (Ivy and Bean Series #1)by Annie Barrows
The moment they saw each other, Bean and Ivy knew they wouldn't be friends. But when Bean plays a joke on her sister, Nancy, and has to hidequickIvy comes to the rescue, proving that sometimes the best of friends are people never meant to like each other. Vibrant characters and lots of humor make this a charmingand addictiveintroduction to Ivy and Bean.
The moment they saw each other, Bean and Ivy knew they wouldn't be friends. But when Bean plays a joke on her sister, Nancy, and has to hidequickIvy comes to the rescue, proving that sometimes the best of friends are people never meant to like each other. Vibrant characters and lots of humor make this a charmingand addictiveintroduction to Ivy and Bean.
Editorial Reviews
"Annie Barrows accomplishes the almost impossible task of reflecting the world of second grader, creating the tension and drama of family and friendships in language that can be read easily by child who recently graduated from easy readers to early chapter books. " Lisa Von Drasek, Children's Librarian, Bank Street College of Education
Heidi Hauser Green
Product Details
- 9780811849098
- Publisher:
- Chronicle Books LLC
- Publication date:
- 05/03/2007
- Series:
- Ivy and Bean Series , #1
- Edition description:
- Reprint
- Pages:
- 120
- Sales rank:
- 30,492
- Product dimensions:
- 5.50(w) x 7.00(h) x 0.40(d)
- Lexile:
- 510L (what's this?)
- Age Range:
- 6 - 10 Years
Meet the Author
Annie Barrows has written many books for adults, but Ivy and Bean is her first series for children. She lives in northern California with her husband and two daughters.
Sophie Blackall is an Australian illustrator whose books include Ruby's Wish and Meet Wild Boars. She lives in Brooklyn, New York.
Brief Biography
- Hometown:
- Berkeley, CA
- Date of Birth:
- August 24, 1962
- Place of Birth:
- San Diego, CA
- Education:
- University of California at Berkeley, B.A. in Medieval History; Mills College, M.F.A. in Creative Writing
Customer Reviews
Average Review:
Most Helpful Customer Reviews
See all customer reviews
My daughter is 6 & primarily loves Fancy Nancy books well we had read all of those so I was looking for something similar. I FOUND IT! We LOVE this book even my son liked it, who is also 6. I am going to be purchasing more from this series that is for sure. I love the contrast between Bean who is a tomboy, loves creating "adventures for the to get into and Ivy who at first you think is a girlie girl but soon find out she has a few crazy ideas of her own. I recommend this book highly!
They are awesomeee!!! I love them!!! ;)))))) theres nothing negative to say about them
Seven-year-old Bean does not want to be friends with Ivy. Her mother keeps telling her that Ivy seems like a very nice girl, but Bean knows what that means. Nice means prim and proper and sitting quietly reading big books. Nice means boring. At least, Bean thought Ivy was boring. When she plays a trick on her big sister and Ivy offers a quick hiding place, Bean isn't so sure. Nice is supposed to be boring. And Ivy does seem nice. But she's also training to be a witch. Besides, how nice can anyone be who has a vast supply of face paint, her own wand, and a spell that involves lots of worms? Bean and Ivy didn't plan to be friends, but they might be a perfect match in Ivy and Bean (2006) by Annie Barrows and Sophie Blackall (illustrator). Ivy and Bean is the first book in the series which is very popular with younger readers. The text is not as advanced as the Clementine or Ramona books but the characters all have similar qualities that will appeal to readers looking for girls with spunk. This story was not as compelling, for me, as the Clementine series but it was a fun fast read that will work for young readers and reluctant readers. Blackall's illustrations add a lot of appeal with her delightfully horrifying pictures of Bean's horrible older sister and Ivy's wonderfully scary witch attire. There are some surprisingly vocal negative reviews (seen on Amazon) accusing the book of promoting everything from bad behavior to witchcraft. To such concerns all I can say is books don't make ill-behaved children anymore than guns kill people all on their own. At its core Ivy and Bean is nothing more and nothing less than a sharp book about two singularly creative girls who are ready and willing to make their own fun be it with pranks or a new friendship. Possible Pairings: Clementine by Sarah Pennypacker and Marla Frazee, Dessert First by Hallie Durand and Christine Davenier, Ramona Quimby, Age 8 by Beverly Cleary
I love ivy and bean
I loved it! Cant wait to get #2
I remember last year when my mom said I could pick out any book. I picked Diary of a Wimpy Kid, but Mommy was bugging for me to check out Ivy and Bean. But I was like " Diary of a Wimpy Kid is good. " And then when I started 2nd Grade, My teacher told us pick out a chapter book, by the time I got there, there only one left. And you guessed it. Ivy and Bean. Soon math class was over. And my teacher said " Okay class, 20 minute break. Take out your chapter books." And then I read it. I fell in love with it!!!!!! I recommend this to people who start 3rd Grade ( that is the grade that im in ). Signed, a Ivy and Bean fan, Paris.
I really enjoyed reading "Ivy and Bean" these 2 girls never wanted to meet.Bean didn't even need Ivy,all the kids in the neighborhood came to Bean so they could play.And Ivy didn't need Bean,she was more interested in magic and potions... but Ivy and Bean meet.i would tell you more but then i'll end up telling yal the whole story.i really think u should read this book.
This book is so good!
I love this book
This book does not really deserve bad comments
It was an easy read but great wish they were longer
It is a good book with trost and friend ship. Thats why i think it shood be a 4 stare
Ok, so I am tweleve and i still love these books!!! I have been reading them since, i dont know , since i was 7? six??? I love these books and in my mind, anybody can read this book and still have a good time with it.
I love Ivy and Bean I have book 1,6,7,and 8 and Bean is my favirite because she has really funny and she is so like me I'm funny and I make fuuny noises and I have ideas like and I have brown hair and si does Bean.
Adore this book!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!! ;)
The main charactors in the book Ivy and Bean are Ivy and Bean. Bean plays a trick on her older sister then Ivy needs to help. It is always a nice, blazing hot day when their adventures begin. Her mom would be so mad at her and ground her for her life. My favorite part of the book is when Ivy helps Bean do a halarious trick on her older sister, Nancy. I don`t want to tell you what happens so read Ivy and Bean to find out!!!!!!!!! I think it is a great book to share with your friends and I also love this book because it is about friends. It is a great book to read to your friends to have fun. I think you can count at least 20 adjectives in this book. Also if you don`t have a lot of friends you can learn how to get friends in this book. I would recommend all kids to read Ivy and Bean. That is why Ivy and Bean is a great book for kids!!!
My daughter really enjoys reading Ivy and Bean. She is in 1st grade and it challenges her reading skills. She has recommended this series of books to her friends.
Im 13 and read these exelent theres no crush factor but its still good
Thos book is really good for 7-8 year olds i loved this book and serise as a kid i am now 10 years old but i still injoy it! I highly recemend this book!!!!!!!!!!
Its fun and an amazing book anddddd you should read the rest of the siries
I love all Ivy and Bean books
First time reading the Ivy and Bean series. I thought it was a wonderful young read! Shows children not to judge others for being different, or quiet. Great imagination! Recommended.
Wanted to find a series to encourage my 7 yo granddaughter to develop an interest in reading. She loved Ivy & Bean and I bought the entire series! Highly recommend the series.
A fun story children would enjoy, but please don't try the pranks.
Im in the 7 th or 8 th chapter but o far the book is really good. My mom let me get a free sample and it turned out pretty good. I would defenetly recomend this book.


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National Institute of Mental Health and Neuro Sciences has released the notification for the recruitment of JRF posts. Eligible candidates can appear in walk-in-interview on 09-02-2016.
Post Details:-
Post Name:- Junior Research Fellow
Vacancies:- 02
Age Limit:- max. 30 years
Pay Scale:- Rs. 25,000/- pm + 30% HRA
Qualification:- M.A/M. Sc in Psychology/Clinical Psychology/ Social Work/ Life Science discipline with NET or GATE. (Non NET/GATE candidate can also apply; on selection they will get 10% less salary)
How to Apply:-
Eligible candidates can appear in walk-in-interview along with their bio- data, copies of all necessary documents (also original) on 09-02-2016 at 10:30 AM at Committee Room, Administrative Block, NIMHANS, Bangalore- 29.
- Candidates are requested to bring original documents at the time of interview.
- Candidates are requested to register their names between 10:00 AM to 10:30 AM.
Selection Procedure:- Interview
Details of interview:-
Date:- 09-02-2016
Time:- 10:30 AM
Venue:- Committee Room, Administrative Block, NIMHANS, Bangalore- 29
For More Details:- Click Here


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A novel polymorphism of the GP78 gene is associated with coronary artery disease in Han population in China
Cha E.,Xinjiang Medical University |
Fu Z.-Y.,Xinjiang Medical University |
Ma Y.-T.,Xinjiang Medical University |
Zhu Q.,Xinjiang Medical University |
And 2 more authors.
Lipids in Health and Disease | Year: 2014
Background: GP78 is a membrane-anchored ubiquitin ligase mediating the degradation of 3-hydroxy-3-methylglutaryl-CoA coenzyme A reductase (HMGCR) and Insig-1, which was very essential for the synthesis of cholesterol process. Cholesterol levels have a causal role in the development of cardiovascular disease. The aim of the present study was to assess the association between the human gp78 gene polymorphism and coronary artery disease (CAD) in a Han and Uygur population of China. Methods: We used two independent case-control studies: a Han population (602 CAD patients and 572control subjects) and a Uygur population (374 CAD patients and 376control subjects). All CAD patients and controls were genotyped for the same three single nucleotide polymorphisms (SNPs) (rs731119, rs2617849and rs2440472) of gp78 gene by a Real-time PCR instrument. Results: In the Han population, for total and men, the distribution of SNP3 (rs2440472) alleles and the dominant model (AA vs AG + GG) and recessive model (GG vs AG + AA) showed a significant difference between CAD and control participants (for allele: P = 0.003 and P = 0.002, respectively; for dominant model: P = 0.041 and P = 0.026, respectively; for recessive model: p = 0.004 and p = 0.004, respectively).The significant difference in both the two models was retained after adjustment for covariates (for dominant model OR:0.760, 95% confidence interval [CI]:0.584-0.99, P = 0.042; OR:0.686, 95% CI: 0.498-0.946, P = 0.022, respectively; for recessive model OR: 1.451, 95% CI: 1.067-1.974, P = 0.018; OR: 1.789, 95% CI: 1.219-2.627, P = 0.000). Our data was also assessed via haplotype-based case-control studies. For the Han population, for total, The G-T-G haplotype in CAD was significantly higher than that in the control group (P = 0.02), and the G-C-A haplotype in CAD was significantly lower than that in the control group (P = 0.0443), And for man, the G-T-G haplotype in CAD was significantly higher than that in the control group (P = 0.0048). Conclusions: The GG genotype and G allele of rs2440472 in gp78 gene could be a risk genetic marker of CAD in Han population in China. © 2014 Cha et al.; licensee BioMed Central Ltd. Source
Prevalence of major cardiovascular risk factors and adverse risk profiles among three ethnic groups in the Xinjiang Uygur Autonomous Region, China
Tao J.,Xinjiang Medical University |
Ma Y.-T.,Xinjiang Medical University |
Xiang Y.,Xinjiang Medical University |
Xie X.,Xinjiang Medical University |
And 8 more authors.
Lipids in Health and Disease | Year: 2013
Background: Prevalence of cardiovascular disease (CVD) risk factors have been scarcely studied in Xinjiang, a multi-ethnic region. Methods. Multi-ethnic, cross-sectional cardiovascular risk survey study in Xinjiang, including individuals of Uygur (n = 4695), Han (n = 3717) and Kazakh (n = 3196) ethnicities, aged 35-74 years. Analyses involved 11,608 participants with complete data enrolled between October 2007 and March 2010. Results: There were differences in age-standardized prevalence of CVD risk factors between the three groups (all P < 0.001). Hypertension, obesity and smoking rates were higher among Kazakh (54.6%, 24.5%, and 35.8%, respectively). Dyslipidemia prevalence was higher among Uygur (54.3%), and diabetes prevalence was higher among Hans (7.1%). Age-standardized prevalence of adverse CVD risk profiles was different across different ethnicities. Compared with the Han participants, the Uygur and Kazakh had more CVD risk factors (P < 0.001). Compared with the Han participants, the adjusted odds ratios of 1, 2, and ≥3 risk factors profiles for Kazakh and Uygur participants were higher (all P < 0.001). Conclusions: The present study showed the pervasive burden of CVD risk factors in all participant groups in the Xinjiang region. Three major ethnic groups living in Xinjiang had striking differences in the prevalence of major CVD risk factors and adverse risk profiles. Ethnic-specific strategies should be developed to prevent CVD in different ethnic groups, as well as to develop strategies to prevent future development of adverse CVD risk factors at a younger age. © 2013 Tao et al.; licensee BioMed Central Ltd. Source
CYP2C19 Phenotype, Stent Thrombosis, Myocardial Infarction, and Mortality in Patients with Coronary Stent Placement in a Chinese Population
Xie X.,Xinjiang Medical University |
Ma Y.-T.,Xinjiang Medical University |
Yang Y.-N.,Xinjiang Medical University |
Li X.-M.,Xinjiang Medical University |
And 5 more authors.
PLoS ONE | Year: 2013
Background: Several studies have indicated that CYP2C19 loss-of-function polymorphisms have a higher risk of stent thrombosis (ST) after percutaneous coronary interventions (PCIs). However, this association has not been investigated thoroughly in a Chinese population. In this study, we aimed to determine the effect of CYP2C19*2 and CYP2C19*3 loss-of-function polymorphisms on the occurrence of ST and other adverse clinical events in a Chinese population. Methods: We designed a cohort study among 1068 consecutive patients undergoing intracoronary stent implantation after preloading with 600 mg of clopidogrel. CYP2C19*2 and CYP2C19*3 were genotyped by using polymerase chain reaction-restriction fragment length polymorphism analysis. The adverse clinical events recorded were ST, death, myocardial infarction (MI), and bleeding events. The primary end point of the study was the incidence of cumulative ST within 1 year after PCI. The secondary end point was other adverse clinical outcomes 1 year after the procedure. Results: The cumulative 1-year incidence of ST was 0.88% in patients with extensive metabolizers (EMs) (CYP2C19*1/*1 genotype), 4.67% in patients with intermediate metabolizers (IMs) (CYP2C19*1/*2 or *1/*3 genotype), and 10.0% in patients with poor metabolizers (PMs) (CYP2C19*2/*2, *2/*3, or *3/*3 genotype) (P<0.001). The one-year event-free survival was 97.8% in patients with EMs, 96.5% in patients with IMs, and 92.0% in patients with PMs (P = 0.014). Multivariate analysis confirmed the independent association of CYP2C19 loss-of-function allele carriage with ST (P = 0.009) and total mortality (P<0.05). Conclusion: PM patients had an increased risk of ST, death, and MI after coronary stent placement in a Chinese population. © 2013 Xie et al. Source
Prevalence, awareness, treatment and control of dyslipidemia among adults in Northwestern China: The cardiovascular risk survey
Luo J.-Y.,Xinjiang Medical University |
Ma Y.-T.,Xinjiang Medical University |
Yu Z.-X.,Xinjiang Medical University |
Yang Y.-N.,Xinjiang Medical University |
And 5 more authors.
Lipids in Health and Disease | Year: 2014
Aim. The aim of this study was to estimate the prevalence, awareness, treatment, and control of dyslipidemia in Xinjiang, China. Method. Stratified sampling method was used to select a representative sample of the general population including Chinese Han, Uygur, and Kazak in this geographic area. Seven cities were chosen. Based on the government records of registered residences, one participant was randomly selected from each household. The eligibility criterion for the study was ≥ 35 years of age. Results: A total of 14,618 participants (5,757 Han, 4,767 Uygur, and 4,094 Kazak), were randomly selected from 26 villages in 7 cities. The prevalence of dyslipidemia was 52.72% in the all participants. The prevalence of dyslipidemia was higher in Han than that in the other two ethnic (58.58% in Han, 48.27% in Uygur, and 49.60% in Kazak, P < 0.000). The prevalence of dyslipidemia was higher in men than that in women (56.4% vs. 49.3%, P < 0.000). Among the participants with dyslipidemia, the proportion of those who aware, treat, control of dyslipidemia were 53.67%, 22.51%, 17.09% in Han, 42.19%, 27.78%, 16.20% in Uygur, 37.02%, 21.11%, 17.77% in Kazak. Conclusion: Dyslipidemia is highly prevalent in Xinjiang. The proportion of participants with dyslipidemia who were aware, treated, and controlled is unacceptably low. These results underscore the urgent need to develop national strategies to improve the prevention, detection, and treatment of dyslipidemia in Xinjiang. © 2014 Luo et al.; licensee BioMed Central Ltd. Source
Association of interaction between smoking and CYP 2C19*3 polymorphism with coronary artery disease in a uighur population
Yang Y.-N.,Xinjiang Medical University |
Wang X.-L.,Xinjiang Medical University |
Ma Y.-T.,Xinjiang Medical University |
Xie X.,Xinjiang Medical University |
And 4 more authors.
Clinical and Applied Thrombosis/Hemostasis | Year: 2010
Objectives: Cytochrome P450 (CYP) 2C19 is expressed in vascular endothelium and metabolizes arachidonic acid to biologically active epoxyeicosatrienoic acids (EETs), which are potent endogenous vasodilators and inhibitors of vascular inflammation. The purpose of this study is to explore the relationship between the interaction of CYP2C19*3 polymorphism and smoking and coronary artery disease (CAD) in a Uighur population. Methods: In a Chinese Uighur case-control study of patients with CAD (n = 336) and healthy controls (n = 370), we investigated the roles of polymorphism in the CYP2C19 gene by the use of polymerase chain reaction restriction fragment length polymorphism (PCR-RFLP) analysis. Results: The CYP2C19*3 AG + AA genotype was significantly more prevalent in patients with CAD (6.25.0% vs 2.96%; P =.03). Multiple logistic regression analysis showed 4 independent risk factors: the interaction of CYP2C19*3 and smoking (OR 7.22, 95% confidence interval [CI] 2.32-10.23; P =.009), smoking (OR 3.23, 95% CI 1.72-5.44; P =.003), blood sugar (OR 2.12, 95% CI 1.03-4.21; P <.01), and hypertension (OR 1.74, 95% CI 0.98-2.34; P =.013). Conclusions: The CYP2C19*3 polymorphism and CAD were synergistically and significantly associated in Chinese Uighur patients. Source


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Five things for pharma marketers to know: Wednesday, February 22, 2017
Audit says MD Anderson Cancer Center mismanaged Watson partnership; Icahn takes stake in BMS; Sarepta sells priority review voucher to Gilead
Deloitte taps Havas Lynx's Mickelberg as MD
Dennis Urbaniak has also been named chief digital officer at Havas Lynx.
Read the complete January 2017 digital edition
Here you'll find everything you need to know from MM&M's January 2017 issue, including our health-tech preview, a deep dive into data science, and report on digital innovation from Japanese drugmakers.
Five things for pharma marketers to know: Tuesday, February 21, 2017
Pharma industry remains focused on Alzheimer's, despite setbacks; few new diabetes drugs in development; the FDA issues complete response letter to Trevena
How VAYA Pharma used Facebook ads for its ADHD campaign
The campaign would require a two-fold approach: Facebook link ads and Facebook Audience Network.
WebMD considers sale or merger
Drugmakers are becoming much more cautious with their budgets, WebMD executives said.
Five things for pharma marketers to know: Friday, February 17, 2017
Microsoft reenters healthcare market; Trump accuses Cummings of avoiding drug-pricing meeting; Trump says ACA replacement plan to be unveiled in March
Roche gears up to enter loaded hemophilia A drug market
A loaded hemophilia A drug market is an indication patients in and around it are well-served, but that hasn't stopped contenders such as Roche's emicizumab.
Five things for pharma marketers to know: Thursday, February 16, 2017
The FDA approves Valeant's psoriasis drug; PhRMA to review its membership criteria; Lions Health announces pharma and health and wellness jury presidents
Industry hires and promotions: February 2017
Novo Nordisk appoints new CEO, and more people moves for you to know about
Five things for pharma marketers to know: Wednesday, February 15, 2017
Pharma execs raise concerns about Trump's plans for the FDA; Merck ends study of experimental Alzheimer's drug; Amgen seeks new indication for Blincyto
Top 25 rare disease brands, by sales
Teva Pharmaceutical Industries' Copaxone is by far the top-selling drug, bringing in $3.2 billion in U.S. sales in 2015.
Orphan drugs face criticism on prices — and from patients
When discussing the nation's ability to stomach orphan drug costs, an analyst has called the price tag "the straw that breaks the camel's back."
On drug pricing, Acorda CEO is optimistic
Acorda CEO Ron Cohen applauded Marathon's move to pause the commercial activities for its new DMD drug.
Five things for pharma marketers to know: Tuesday, February 14, 2017
More older Americans are taking at least three psychiatric drugs; Marathon to pause launch of Emflaza; Aetna and Humana call off deal


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Lecompton area man flown to hospital following accident
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The Angel Investor's Handbook
How to Profit from Early-Stage Investing
By (author) Gerald Benjamin Joel B. Margulis
Format: Hardback
Normal Price: $113.95
Your Price: $102.56 AUD, inc. GST
Shipping: $7.95 per order
You Save: $11.39! (10% off normal price)
Plus...earn $5.13 in Boomerang Bucks
Availability: Available to Backorder, No Due Date for Supply
Angel Investor's Handbook by Gerald Benjamin
Book DescriptionMany of today's high-net-worth investors are turning their attention to early-stage investing in emerging companies. They know just how successful and lucrative funding a start-up venture can be. Savvy angel investors can foresee distant but potentially huge returns from pre-IPO companies. There are scores of hungry entrepreneurs in search of capital and lots of money to be invested. But, matching the right entrepreneurs with wise investors, so that both can profit, is the challenge in new enterprises. Gerald Benjamin and Joel Margulis demonstrate that the real pitfall for potential investors is an incomplete understanding of the complexities of early-stage investing. At the same time, the angel capital market offers few mechanisms for bringing investors and entrepreneurs together, while securities regulations restrict communication between sophisticated investors and promising new businesses. So, where do the uninitiated start, and how do they separate the wheat from the chaff? In this ground breaking work, Benjamin and Margulis offer angel investors a hands-on manual for profiting from early-stage, private equity deals. They show how to develop investment criteria and overall game plans, locate viable investment opportunities, assess and manage risks, negotiate the most favorable deal terms, conduct thorough due diligence, and plan the all-important exit strategy.
Buy Angel Investor's Handbook book by Gerald Benjamin from Australia's Online Bookstore, Boomerang Books.
Book DetailsISBN: 9781576600764
(238mm x 160mm x 30mm)
Pages: 351
Imprint: Bloomberg Press
Publisher: Bloomberg Press
Publish Date: 1-Jul-2001
Country of Publication: United States
Other Editions...
Books By Author Gerald Benjamin
Angel Capital, Hardback (February 2005)» View all books by Gerald Benjamin
Get the business insight that has raised millions in capital funding for over 50,000 entrepreneurs. If you're an entrepreneur or own a small, fast-growing businesses, this work provides a complete toolkit for raising capital in a challenging economic landscape.
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Author Biography - Gerald Benjamin
GERALD A. BENJAMIN, MS, is Senior Managing Partner of International Capital Resources (ICR) in San Francisco, and is recognized by entrepreneurs, investors, venture organizations, and academic entrepreneurial finance programs as one of the nation's leading authorities on the angel capital market. Over 50,000 entrepreneurs have attended Benjamin's seminar, "Angel Financing: How to Raise Private Equity for the Early-Stage Venture," which has been sponsored and presented by over 200 prominent entrepreneurial and investor organizations in the United States. His research in the field has been covered by the Wall Street Journal, Time, Barron's, Investor's Business Daily, and many other publications. Benjamin received his BA and MS degrees from the University of San Francisco. JOEL B. MARGULIS is a member of the English Department at San Francisco State University and has authored and coauthored a number of books on a variety of subjects. He received his BA in history and MA in English from the University of Missouri-Columbia. Margulis is a freelance writer who has published books and articles on a range of business and finance topics.
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Biography of Mark Ashdown
Discover your family's story. Enter a grandparent's name to get started. Start Now Mark Ashdown, deceased, for many years a resident of Port Byron and Coe Townships, was, during his lifetime, one of the best known and respected of the many long time residents of this county. He was born in County Kent, in England. on the third day of June, 1851, and died May 31, 1907. He came to America early and in late years became prominent in local public life as an ardent Prohibitionist and the holder of various public offices in this county at various times. Not until early in 1907 did death finally claim Mr. Ashdown, after he had suffered for six years with paralysis. The late citizen of Rock Island County, here mentioned, was the son of Edward and Ann Bakurst Ashdown, both of County Sussex, England. Edward Ashdown, father of Mark, came to America in 1842, accompanied by his two sons, Henry and Mark, and after spending thirteen months in Macedon, Wayne County, New York, they returned to England, where the elder Mr. Ashdown died soon afterward. In the fall of 1850 Mark and his brother returned to New York State and again located in Wayne County. Until 1855 Mark remained there and in that year emigrated to Illinois, spending one Summer in Port Byron. Then going to Canoe Creek Township of Rock...Read More


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We, at CSIR-SERC, Chennai , commit ourselves to achieve excellence in all our R&D activities and in providing high quality S&T outcomes, in the field of Structural Engineering, to the industry and the society at large.
We aim to be at the cutting edge of science, engineering and technologies through continuous enhancement of knowledge, expertise, facilities and performance towards ensuring safety and sustainability of structures.
Quality Objectives
> CSIR-SERC will strive to follow the Quality Policy towards achieving the goals of the Charter.
> Publish minimum 75 technical papers in journals/conferences in a year.
> Achieve a minimum of 1/4 of the human resource component of the budget through externally funded projects.
> Conduct at least one national seminar / two advanced courses in a year.
> Sponsor minimum 25% of scientists and technical staff and 10% of administrative staff for participating in training programmes/courses/ seminars in a year as part of HRD activities.
> Extend facilities for minimum of 50 post graduate and undergraduate students in a year for undertaking their thesis/project work
For More Information Download : ORGANIZATIONAL STRUCTURE OF CSIR-SERC