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Chevrolet Camaro Concepts - Click above for high-res image gallery
Camaro Concept
13SEMA 2009: Handful of Chevy Camaro concepts preview new options
- Frank Filipponio
- Nov 3, 2009
- 13
29SEMA 2008: Camaro Accessories, Camaro Black, and Earnhardt, Jr. Camaro LIVE
- Jonathon Ramsey
- Nov 3, 2008
- 29
Click the image above for a high-res gallery of 2008 SEMA Camaro concepts
17Transformers: Corvette concept, Bumblebee Z28 in the buff
- Jonathon Ramsey
- Jun 22, 2008
- 17
So a couple of weeks ago we asked you to help us identify a mystery car on the set of Transformers 2. Quite a few of you guessed it was some sort of Corvette concept, or the C7 Corvette due in 2010. For those of you who guessed Corvette concept, you were right. The picture above is that concept, and according to speculation it is getting some paint work done in the house of Chip Foose. We don't know if these pics were taken before or after the car's closeup, but we hope it was afterward and that
24Camaro SS spied on set
- Jonathon Ramsey
- Jun 22, 2008
- 24
Ladies and gentlemen, you are looking at your 2010 Chevrolet Camaro SS. It wasn't found on the set of Transformers2, but on location for a Christian Slater television show that'll debut this Fall on NBC. It's a very tastefully done brawn job. The SS badge takes its place in the lower right corner of the grille, with another small badge on the rear bumper. The front spoiler that a number of commenters took issue with on the Bumblebee mod looks to be, if anything, an aftermarket piece. But there's
18VIDEO: 2010 Chevy Camaro cruising to classic rock
- Jonathon Ramsey
- Mar 24, 2008
- 18
Click above to view video
97Lutz says GM considering 2.0-liter turbo for Camaro
- Jeremy Korzeniewski
- Mar 19, 2008
- 97
A four-banger in a Camaro! Blasphemy you say? Could be, but what four-pot are we talking about? In this case, the General's car czar Bob Lutz suggests that the new 2010 Camaro due next February could offer the same 2.0 liter direct-injected engine used in the Saturn Sky Redline, Pontiac Solstice GXP and the SS versions of the Chevy HHR and Cobalt. Before dismissing the turbo-four immediately, consider the top-of-the-line engine options the Camaro offered after the last oil-embargo-driven doomsda
282009 Chevy Camaro a no-show at auto shows
- Chris Shunk
- Jan 22, 2008
- 28
We've seen the Camaro coupe and convertible concepts over the past two years at venues like the Detroit and Chicago auto shows. A stunning yellow Camaro also had the starring role on the biggest Hollywood blockbuster of 2007. We're even getting "spy shots" of the production Camaro taken by General Motors engineers that are posted on the GM Fast Lane blog. What we won't see any time soon is a production Camaro being unveiled during 2008. Kicking Tires quotes Chevy execs as saying that the company
24Autoblog's #1 Most-Read Post of 2006
7SEMA panel celebrates muscle cars, then and now
- Mike Magda
- Oct 30, 2006
- 7
15Full-body Bumblebee snapped on Transformers set
Once again the set of the upcoming Transformers film has been infiltrated, and this time a full-body pic of Bumblebee laying prostrate supine flat on his back made it off the lot. It's a perfect view to analyze the Autobot's form and pick out pieces parts from the Chevrolet Camaro concept. The most obvious is Bumblebee's chest plate, which appears to made out of the corners of the Camaro concept's front bumper. Though many have panned the decision to base Bumblebee on the Camaro concept rather t
23Lutz thanks blogosphere for Camaro support
Though many factors were responsible for the new Camaro's path to production, Bob Lutz took some time on General Motors' FastLane Blog to recognize the support the car received from the blogosphere. While Lutz only mentions the comments left on FastLane Blog, we can add that the support for the Camaro on Autoblog has been robust to say the least. After posting on the Camaro Concept's introduction at the North American International Auto Show in January, you all left 1,074 comments on the post. D
69BREAKING! It's really official now - GM's Wagoner confirms Camaro production
- Stuart Waterman
- Aug 10, 2006
- 69
34Jay Leno shows off the Camaro concept
- Stuart Waterman
- Jul 10, 2006
- 34
7GM teams up with Discovery for TV documentary
- Eric Bryant
- Jun 6, 2006
- 7
To help rectify a relative lack of automotive content in the world of TV documentaries, General Motors and the Discovery Channel are teaming up to bring a four-part series to the small screen in 2007. The new series will follow eight interns as they each take a vehicle - based on GM's hydrogen fuel cell technology - from the drawing board through the design process. The series promises a "rare look" at several aspects of automotive industry and product development process, such as the
63Camaro convertible already approved?
Haven't gotten the latest issue of Motor Trend in the mail yet, but this article from Post-Gazette.com references the current July issue out on newsstands that claims General Motors has already approved a convertible Camaro for production. Umm ... now we all know the Camaro Concept (and the Dodge Challenger Concept, as well) will likely go into production, but last we heard the business case was "still being fleshed out." Reportedly 100,000 Camaros will need to be sold in order for Chevy to star
40Camaro and Mustang do battle in Transformers: The Movie
The upcoming live-action Transformers movie will feature a matchup with which most Autoblog readers are intimately familiar: Camaro versus Mustang. A bright orange Chevy Camaro Concept that's more than meets the eye will play the good-natured Transformer named Bumblebee, which has traditionally been portrayed by the Volkswagen Beetle. Meanwhile, a Decepticon named Brawl that reportedly "jacks-up poor Bumblebee" is being played by the Ford Mustang.
19Dodge insists Challenger does not yet have green light
In a questionable PR move, Chrysler's VP of Communications Jason Vines told Inside Line that despite internet reports of a supplier already working on components for the production version of the Dodge Challenger Concept the company has not yet given the pony project a green light. Vines, who is on the product strategy team for the Challenger, says a business case is being produced "fast" and a decision should be reached by the end of the year. We already know Chevy needs to produce 100,000 Cama
58The making of the Camaro Concept
- Eric Bryant
- May 6, 2006
- 58
11Camaro Concept versus Mustang debate goes digital
Many of us have already taken in Motor Trend's May issue cover story in which an impatient MT staff pits Chevy's Camaro Concept, not due out until 2008 if at all, against the Ford Mustang in a digital duel. The comparison occurred in a virtual world created by a simulation program called CarSim. While data on the actually-in-existence Ford Mustang was easy to come by, editors from MT has to consult with GM to cull information on the 2009 Camaro to use in the simulation.
- Biggest automotive sales disappointments
- Fastest-depreciating cars in the United States
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You can gain unprecedented access to The Royal Mint to discover the people and events behind the coins in your pocket.
Discover more on the origins of these fantastical creatures who represent and guard Her Majesty The Queen.
The Royal Mint is to commemorate the Sapphire Jubilee
Amongst coins on trial in ancient quality assurance ceremony
Partnership to build digital gold product on blockchain to be available in 2017
Accreditation against new standard
Background Information
The United Kingdom 2p coin was introduced on the 15 February 1971 with the introduction of a new decimal currency system. The other two coins issued at this time were the 1/2p and 1p coins.
To avoid confusion between the old and new coinage all three coins had the word 'NEW' incorporated into the reverse design. This was subsequently removed in 1982.
The first copper-plated steel 2p coins were struck in 1992. The reason for this change was the increase in the price of metals on the world markets. The coins have a mild steel core and are electroplated with copper - consequently they are magnetic.
The 2p coin is legal tender for amounts up to 20p.
*Mintage figure based on UK decimal coins issued into general circulation during from 01/04/13 to 31/03/14
50p, £1 and £2 albums for budding collectors starting from £5
Honouring those who fought for control of the skies 75 years ago.
The third coin in our £100 coin series

subset: commoncrawl


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More Videos...
Part 7: My 76 Mazda RX-5 Cosmo Restoration - Intake and Exhaust Porting
Has it been nearly a month since my last episode? Wow, time does indeed fly. I've been quite busy preparing to build the engine. So in part 7, I cover the intake and Exhaust porting. The engine is being built with GSL-SE 6 port plates and the Cosmo rotor housings as the basis for a 6 port turbo setup. This port job is fairly conservative, only opening up the primary ports a little and bringing the Exhaust ports close to 2nd gen RX-7 specs. The goal is to maintain fuel economy, low and midrange torque, and idle quality. This episode covers everything involved in porting including: marking out the new ports, grinding the port shape, smoothing the bowls, smoothing port to runner transitions, smoothing the runners, grinding and blending the Exhaust ports.
Complete Rotary 13B Rebuild - Engine (Part 3)
Do-it-Yourself knowledge to rebuild the popular 13B rotary engine for a Series 6 Mazda RX7. This part will tackle the assembly of the engine. This includes preparation and fitting of seals, gaskets into rotor housing and end plates. This will show you how to assemble the engine block together correctly with the rotors and apex seals to the manufacturers tolerances and specifications. The final assembly of the engine is completed with standard tools and leaves them ready for the final part 4 'Setting the end-float'. If you could please take the time to Subscribe Like and Share my video to spread the word, I would appreciate it. I also wanted to start getting some videos up putting a Veilside Fortune Bodykit on my Rx7 for viewers over the world so any donations would be much appreciated to get this project up and away. Link is on right hand side on main channel page or Link is http://www.gofundme.com/8oc9ck Thanks for your time
BDC Porting - Front Secondary w/ Bridgeport
BDC Motorsports http://www.bdcmotorsports.com Quick video showing a half-bridgeport plus street port I performed on a Series 5 front iron housing. Video taken in summer '04.
How To Rebuild an Port a Rotary Engine : Part 5
Please vote for my video http://on.fb.me/HEooS1 In this video I get my turbo's cleaned up and ready to put back together, and I start porting the center iron.


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Certificate Program Overview
In engineering and science today there is a trend toward the use of modern, sophisticated mathematical techniques of both computational and theoretical types. One reason for this is the revolutionary development of computational resources. Modern engineers and scientists have at their disposal user-friendly, powerful computers with sophisticated graphics to display results. Such modeling and simulation techniques are also increasingly used in the biological and social sciences, especially economics. With these tools, interdisciplinary problems that are complex and nonlinear have become the norm in contemporary science and engineering. The engineer/scientist must learn to use such tools wisely, accurately, and to their full power. A natural time to be introduced to such skills is as an undergraduate. During these formative years the modern engineer or scientist should learn the use of mathematical and computational techniques in an interactive, interdisciplinary environment. At Princeton, the Program in Applied and Computational Mathematics offers a small group of undergraduate students the unique opportunity to learn to perform accurate and controlled numerical studies and, perhaps most important, exposes them to the philosophy and tools of interdisciplinary applied mathematics in a very personal and individualized manner. Students who complete the prescribed requirements are awarded a certificate in Applied and Computational Mathematics. Recently a new option has become available to undergraduate math majors who intend to pursue the PACM certificate, the applied math track.
Formal application to the program typically occurs toward the beginning of the junior year of study, although sophomores who display high aptitude may be considered as well. Before February 1st of their junior year, students should submit a one-page proposal outlining their course selection and giving some idea of their choice of independent work (paper/ course project/ computational laboratory) or thesis. Proposals should be addressed to the undergraduate representative and sent in care of Gina Holland, Room 205 Fine Hall. Students accepted into the program will be notified by means of a formal acceptance letter. Students interested in more information about the program should contact the undergraduate representative, Prof. Paul Seymour, for a meeting.
Faculty Research and Interests


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Sweet Potato Casserole
Total Time
1hr 5mins
Prep 25 mins
Cook 40 mins
This is a family favorite at the holidays!
Ingredients Nutrition
- 3 cups sweet potatoes, boiled and mashed
- 1 cup sugar
- 1⁄2 teaspoon salt
- 2 eggs, beaten
- 1⁄4 cup butter, soft
- 1⁄2 cup milk
- 1 teaspoon vanilla
- 1 cup brown sugar, packed
- 1⁄2 cup flour
- 1 cup chopped pecans
- 1⁄3 cup melted butter
- Mix all casserole ingredients well and pour into greased 8x10 casserole dish.
- Mix topping ingredients and sprinkle over top of potato mixture.
- Bake at 350 degrees for 35 minutes. Allow to set up a few minutes before serving.
Most Helpful
Sooo good, I could have ate just this for dinner and been happy! I used a little more sweet potatoes than called for since the ones I cooked were rather large. Made the filling a nice fluffy texture; not too dry and not too soupy. The topping made a nice sweet crust on top which was not too sweet at all. Made for 2012 Spring PAC.


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Los Angeles Residents Continue to Report High Levels of Stress
In a survey released today by the American Psychological Association (APA), more than half of Los Angeles residents surveyed cited money, work and the economy as significant sources of stress, although the number citing these as stressors has decreased since 2008. Similarly, the number of Los Angeles residents who said their average stress level is in the extreme range is lower than last year. Less than one-quarter (21 percent) rated their average stress levels as an 8, 9 or 10 on a 10-point scale, compared to about one-third (31 percent) last year. Almost half (47 percent) said their stress has stayed the same over the past year, compared to 36 percent who reported in 2008 that it had not changed since the previous year. And fewer Los Angeles residents expressed strong satisfaction with their job than they did last year (22 percent vs. 33 percent in 2008).
These high and long-lasting levels of stress can contribute to serious physical health problems. Diabetes, heart disease, obesity and high blood pressure are just a few of the diseases linked to chronic stress. In the APA survey, more Los Angeles residents said they have been told by a health provider that they have a chronic condition (71 percent vs. 66 percent nationally). More than the rest of the nation, they reported that they have high blood pressure (34 percent vs. 30 percent nationally) and high cholesterol (31 percent vs. 28 percent nationally).
On a positive note, fewer residents this year reported physical symptoms caused by stress. For example, the number of Los Angeles residents who said they felt irritable or angry dropped 17 points (39 percent in 2009 from 56 percent in 2008) and fewer residents are feeling fatigue (33 percent in 2009 vs. 55 percent in 2008) or experiencing headaches (26 percent in 2009 vs. 46 percent in 2008) because of stress. Also, fewer Los Angeles residents are drinking alcohol to relieve stress (9 percent in 2009 vs. 25 percent in 2008).
"The good news for the region is that fewer people this year are reporting money, the economy, family responsibilities and relationships, among other things, as significant stressors. But with so many of us still so stressed -- that's alarming," said psychologist Dr. Jana Martin, the public education coordinator for the California Psychological Association. "When stress is ignored or managed in unhealthy ways, it will most likely lead to further health problems. This is why it's crucial for people to pay attention to their stress levels and do something about it."
APA's annual survey reveals that nationally nearly a quarter (24 percent) of adults reported experiencing high levels of stress, and half (51 percent) reported moderate stress levels in 2009. Many Americans continued to report that they rely on sedentary activities and unhealthy behaviors to manage their stress (49 percent listen to music, 41 percent read and 36 percent watch television or movies).
Among Americans who received lifestyle change recommendations from a health care provider, few reported that their health care provider offered support to help them make lasting changes -- only 46 percent were given an explanation for recommended lifestyle changes; only 35 percent were offered advice or shown techniques to help make changes; and only 5-10 percent were referred to another health care provider to support the adoption of lifestyle changes. In general, people cited a number of barriers in their efforts to make lasting lifestyle and behavior changes -- lack of willpower (33 percent); not enough time (20 percent); and lack of confidence (14 percent). More than one in ten people cited stress as the barrier preventing them from making lifestyle and behavior changes (14 percent of adults reported they are too stressed to make these changes).
More than the rest of the nation, Los Angeles residents said they were prevented from following through with lifestyle change recommendations due to a lack of willpower (41 percent vs. 33 percent nationally). And 7 percent of those in Los Angeles (vs. 14 percent nationally) said they were too stressed to follow through with lifestyle change recommendations.
The California Psychological Association offers these tips to help manage chronic stress:
The 2009 Stress in America research was conducted online within the United States by Harris Interactive on behalf of the American Psychological Association between July 21, 2009 and August 4, 2009 among 1,568 adults aged 18+ who reside in the U.S. and an oversample of 205 adults aged 18+ who reside in Los Angeles. In the 2008 research, 256 Los Angeles residents were included in the oversample. No estimates of theoretical sampling error can be calculated; a full methodology is available.
The American Psychological Association, in Washington, D.C., is the largest scientific and professional organization representing psychology in the United States and is the world's largest association of psychologists. APA's membership includes more than 150,000 researchers, educators, clinicians, consultants and students. Through its divisions in 54 subfields of psychology and affiliations with 60 state, territorial and Canadian provincial associations, APA works to advance psychology as a science, as a profession and as a means of promoting health, education and human welfare.
Harris Interactive is a global leader in custom market research. With a long and rich history in multimodal research that is powered by our science and technology, we assist clients in achieving business results. Harris Interactive serves clients globally through its North American, European and Asian offices and a network of independent market research firms. For more information, please visit www.harrisinteractive.com.
-- Set limits. List all of the projects and commitments that are making you feel overwhelmed. Identify those things that you absolutely must do in order to survive. Cut back on anything non-essential. -- Tap into your support system. Reach out to a close friend and/or relative. Let them know you are having a tough time and accept their support and guidance. There is no need to face challenging life circumstances alone. -- Make one health-related commitment. One small step like cutting back on your caffeine consumption can have a positive effect. Studies show that without caffeine, people report feeling more relaxed, sleeping better and having more energy. Regular aerobic exercise, such as taking a brisk walk, can lessen your anxiety and reduce your stress. -- Strive for a positive outlook. Looking at situations more positively, seeing problems as opportunities, having realistic expectations, and refuting negative thoughts are all important aspects of staying positive and trying to minimize your stress. -- Seek additional help. If feelings of chronic stress persist, or you are experiencing hopelessness or trouble getting through your daily routine, seek consultation with a licensed mental health professional, such as a psychologist. Psychologists are trained to help you develop strategies to manage stress effectively and make behavioral changes to help improve your overall health. For additional information on managing stress, visit www.apahelpcenter.org.
SOURCE American Psychological Association
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Sketching Together the Modern Histories of Science, Technology, and Medicine
John V. Pickstone
Vol. 102, No. 1 (March 2011), pp. 123-133
Published by: The University of Chicago Press on behalf of The History of Science Society
Stable URL: http://www.jstor.org/stable/10.1086/657506
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ABSTRACT This essay explores ways to "write together" the awkwardly jointed histories of "science" and "medicine"—but it also includes other "arts" (in the old sense) and technologies. It draws especially on the historiography of medicine, but I try to use terms that are applicable across all of science, technology, and medicine (STM). I stress the variety of knowledges and practices in play at any time and the ways in which the ensembles change. I focus on the various relations of "science" and "medicine," as they were understood for a succession of periods—from mainly agricultural societies, through industrial societies, to our biomedical present—trying to sketch a history that encompasses daily practices and understandings as well as major conceptual and technical innovations. The model is meant to facilitate inquiry across topics and across times, including those to come.
© 2011 by The History of Science Society. All rights reserved.


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Bathing in the river or sea and not experiencing any fear, panic or humiliation suggest deliverance from afflictions: if the observer of the dream is grief stricken, his grief will be removed an replaced with happiness; if he is suffering from a disease or sickness, he will be cured; if he is in straitened circumstances, […]
Search Results for: bathing with well water
Here's what we've found for you
Bathing in the sea (or swimming in the sea) foretells of good fortune beyond your wildest dreams. If you bathe in a lake, your difficulties will soon fade away. If you bath in a river, good surprises are coming towards you. If you bathe with others in your dream, it means that someone close to […]
In clean, clear water, a dream of great good fortune; in muddy water, the reverse (Artemidorus). Symbolism obvious.
Bath, Bathing
Being in a bath, or taking many baths, reveal an intense interest in the opposite sex. To bathe with other people, gossip about the dreamer may be disturbing. For a widow or widower, remarriage. Bathing in clear water, business expansion or renovation about the home. Physiologically, dreams of bathing may be due to physical discomfort. […]
Symbolic of cleansing yourself, Ex. 30:19-21. Also symbolic of a place of intimacy and exposure, 2 Sam. 11:2
Bath / Bathing
When we dream of being in the bath, it may indicate the need for cleansing of some old feelings, the need to relax, to let go. We have an opportunity to contemplate what has occurred in the past and to adopt new attitudes. To be wearing a bathing costume denotes a degree of permitted exposure.
Bath / Bathing
For many women a bath can be a relaxing time of contemplation and can, therefore, have that significance in dreams. For men, it is more likely to be functional and, therefore, a time of planning. You might like to read the entries for swimming, washing and water.
(Sauna; Steam room; Sweat room; Rest room) Washing one's dirt with hot water in a dream brings benefits. If one builds a bathhouse in his dream, it means committing a sin or searching for a woman to partake in it, then suffering its consequence. Ifthe bathhouse is heated and the water is lukewarm in the […]
Bathing Suit
If you dream of shopping for bathing suits, you may be worrying about being judged by others. If all the suits feel tight or ill-fitting, you need to protect your reputation by cooling down your activities with boys. If you try on lots of great suits, success is ahead for you. If you dream of […]
Bath / Bathing
From a spiritual perspective, any dream where water is involved suggests an act of cleansing or initiation. Communal bathing depicts innocence and sensuality combined.


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|Looking for software? Click here.
|If you maybe haven't heard yet - ex Marshall and Akai product designer (remember Marshall JMP-1?) has created a guitar amp emulation software plugin called S-Gear, which is simply awesome. Believe me on my word, i own and use (now very rarely) at least five other major amp sim plugins. S-Gear is being used almost exclusively for all guitar work in my music production. Having a guitar amp inside computer has never felt better!
Here you can listen to few my tracks, which demostrate the power of S-Gear. You can listen to more of my music production on Zabukowski's Soundcloud.
Enjoy :)
Articles about Zabukowski in Slovenian language:
Sanjska Rockline reportaža iz koncerta v ORTO baru
Fotografije iz koncerta v ORTO baru
24ur.com - Moški svet: Slovenec, ki je s svojim izdelkom osvojil svet


text: Beauty and the Beast Look Inside Listen Beauty and the Beast Piano, Voice, Alto Voice - IntermediateBy Alan Menken. Arranged by Sandy Lynch - Music Creations Ltd. www.music-creations.co.nz; firstname.lastname@example.com; www.piano-now.com; Instagram; sandy_lynch. Musicals, Movies, TV, Children's Music, Children's Musicals. Score, Solo Part. 5 pages. Published by Sandra Lynch (H0.77079-66212). Available Instantly More info Add to Cart { "catalogRefId":"20140472", "productId":"prod20140472", "quantity":"1" }


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Swiss Croquet
Croquet agenda & events
World Golf Croquet Team Championship — 15th / 20th May 2016 in Bath, England
8th Women's Swiss Golf Croquet Championship— 17th June 2016 in Geneva and is open to all women playing golf croquet in Switzerland
14th Swiss Handicap Golf Croquet Championship — 18th / 19th June 2016 in Geneva, open to all Swiss Clubs
3rd Swiss Golf Croquet Mixed Doubles Open — 25th / 26th June 2016 in Zurich, open to all golf croquet mixed doubles teams
5th Swiss Golf Croquet Open Championship — 6th / 7th August 2016 in Geneva, open to Golf Croquet players
Swiss Croquet Association
Fixtures List 2016: Click to open
Swiss Croquet Clubs
Fixtures List 2016: obtainable by contacting the secretary of the appropriate croquet club.
We wish you a successful and exciting croquet season!
The essential information on croquet
Croquet is a game in which a ball is knocked around a course of hoops with a mallet. Billiard Croquet is the modern version of croquet, the Swiss game! There are many playing versions of croquet and each version has its own rules and court setup. Click for more…..
How to play croquet & its objectives
Billiard Croquet, the Swiss Game!
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The distinguishing features of a croquet player
A typical croquet player is a strategist, a tacticians, above average mental strength, succeeds under pressure, a good judge of distance using eyesight and feeling, the calmness dominates, feeling relaxed and tensionless is not visible but always present, prepared to train hard, a team player, participates in tournaments, a socialite and more. Click for more…
If the above distinguishing features are your characteristics, you should urgently contact your nearest Swiss croquet club (Click to locate your croquet club) and to all those that are not so sure, do the same!
Registrations & Submissions
Keep up to date with all current events and news on croquet by subscribing to the Swiss Croquet newsletter.
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The free registration of your club on Swiss Croquet website is open to all croquet clubs. Further details and registration of your club.
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Big K.R.I.T., Club Red, 8/2/12
Big K.R.I.T.
Anthony Sandoval
Big K.R.I.T. Club Red Thursday, August 2, 2012
See also: Big K.R.I.T.'s Blowing Up, but the Rapper's Got Underdog Appeal Success can sometimes have a funny way of taking the edge away from competitors. In the ever-growing rap game, artists are often a one-hit wonder away from retirement.
Southern rapper Big K.R.I.T. has experienced his fair share of success since 2010's breakout mixtape K.R.I.T. Wuz Here announced his arrival and now with his latest album, Live From the Underground, still giving critic's whiplash, the Mississippi-native is primed for more.
But will he be a "one-and-done" musician that gets fat from too much success? If last night's performance at Club Red in Tempe is any indication, not likely.
Upcoming Events
Born of Osiris
TicketsWed., Mar. 1, 6:30pm
Ugly God & Wintertime
TicketsThu., Mar. 2, 9:00pm
The Australian Bee Gees Show
TicketsFri., Mar. 3, 8:00pm
Isaiah Rashad
TicketsSat., Mar. 4, 7:30pm
Dueling Chicago Quartets
TicketsWed., Mar. 8, 7:30pm
K.R.I.T. tackled each track during his hour long set with so much intensity and veracity that the crowd will be talking about this show for some time.
I got to the venue around the time tour supporter Tito Lopez was scheduled to perform, but he had to scrap his appearance because of a sore throat. Sounding notably hoarse, Lopez came out to apologize to the crowd personally.
At around 10:20 p.m., Los Angeles-native Casey Veggies appeared for a brief showing that really didn't do much to work up the crowd. His laid back beats and swagged-out lyrics mostly fell on deaf ears from where I was standing, until the notes for "Toe Tag" filled the air and got a rise from the audience. But after only a 20-minute set, there wasn't much else to remember.
Casey Veggies
K.R.I.T. turned everything around once he took the stage. With the help of some wall-shaking bass, the kind that makes your shirt tremble against your chest and your teeth rattle, he snapped everyone to attention opening with "Boobie Miles."
"Cool 2 Be Southern" and "4EvaNaDay" picked up the pace and got concertgoers really moving. "You came to the wrong show to be tired," K.R.I.T. warned early in his set. His coarse cries and animated movements energized the crowd closest to the stage, while the rest of the venue showed a healthy bounce.
The rest of the set was full of fan-favorite tracks that brought out plenty of sing-alongs and fist-pumping. Even when he slowed down the pace, his careful croon hit with equal ferocity. Midway through the set he instructed everyone to put their middle fingers in the air and ripped into the bridge to, "I Got This."
"Fuck these haters, fuck these hoes," the crowd responded excitedly. But it proved to only be a teaser. "It ain't time for that song yet," he said. He saved the best for last, choosing to close the show with the outstanding track.
K.R.I.T. tweeted yesterday, "As soon as I jumped off the bus I got attacked by a heat wave." Looks like he brought some heat of his own.
Critic's Notebook:
Last Night: Big K.R.I.T.
The Crowd: Mostly dudes. And some familiar faces from the local hip-hop talent pool.
Overheard in the crowd: "I was 14 the first time I smoked crack."
Random Notebook Dump: I'm way over the horn/siren blare thing.
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Brands Hatch hosts Paralympic cycling
5 September 2012 Last updated at 20:17 BST
There are winners and losers among businesses affected by road closures and diversions near Brands Hatch in Kent, the venue for the Paralympic cycling events.
Petrol station managers Kumar and Judie Asokkumar said they believed the restrictions, in place until Saturday, would cost them £30,000 in lost custom.
But Derek Mathews, manager of the Oasis Cafe, said his takings had doubled since the beginning of the week.


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Tumors actively suppress immune response against themselves. This creates a fundamental barrier to successful immunotherapy, but the underlying molecular mechanisms are still poorly understood. This proposal builds upon the novel discovery that three key molecular pathways - indoleamine 2,3-dioxygenase (IDO), CD40/CD40L and CTLA-4 - all become tightly linked in tumor-bearing hosts, functioning together as a single integrated regulatory network. This innovative model is supported by important new discoveries made during the previous period of support, including the role of IDO in activating highly suppressive Tregs in tumor-bearing hosts;and identification of a novel subset of "reprogrammable" Foxp3+ Tregs that is capable of converting into pro-inflammatory, CD40L-expressing helper T cells under suitable conditions. The current proposal will use informative mouse preclinical models to develop clinically-applicable, mechanistically-based immunotherapy regimens. These regimens will incorporate the first-in human IDO-inhibitor drug 1-methyl-D-tryptophan (1MT), now in Phase I clinical trials, in combination with chemotherapy and active immunotherapy.
Aim 1 will test the hypothesis that the highly suppressive Tregs in tumor-draining lymph nodes (TDLNs) can be de-activated and rendered non-suppressive by simultaneously blocking IDO and providing a strong proinflammatory signal through the CD40/CD40L pathway.
Aim 2 will test the hypothesis that DCs in TDLNs can be licensed for robust and effective cross-presentation of endogenous tumor antigens by preventing the tolerogenic DC phenotype that is induced by IDO-activated Tregs via the CTLA-4/B7/FOXO3 pathway, and simultaneously driving the DC-activating/licensing CD40/CD40L pathway.
Aim 3 will test the hypothesis that the late stages of the CD8+ cytotoxic T cell response (clonal expansion, effector differentiation, and long-term memory formation) can be markedly enhanced by blocking the cell-intrinsic inhibitory effect of CTLA-4 on the CD8+ cells, and that this cell-intrinsic effect of CTLA-4 different from - and acts synergistically with - the upstream cell-extrinsic effects of interrupting the IDO/CTLA-4 loop during the initial priming stage.
These Specific Aims continue the project's strongly translational and pre-clinical therapeutic focus. The overall goal of the current proposal is to develop novel high-potency combination regimens that leverage the synergy of IDO-inhibitor drugs in combination with CD40 agonist antibodies, chemotherapy, and CTLA-4 blockade. The strategies proposed are timely, high-impact, and have a clear path to the clinic. The proposed studies bring new mechanistic insights to bear on the difficult and important clinical problem of identifying highly potent and synergistic multi-aget immunotherapy regimens, and provide testable outcome measures at the molecular level to evaluate whether each proposed strategic intervention is hitting its hypothesized target.
Clinical strategies that use the body's own immune system to kill cancer cells are now poised to enter mainstream cancer therapy. The current proposal addresses a key unmet need in this field, asking what is the best way to combine powerful immunologic therapies so that they take advantage of the natural synergies between the complementary mechanisms and pathways, while minimizing the degree of toxicity to the patient.
|Sharma, Madhav D; Huang, Lei; Choi, Jeong-Hyeon et al. (2013) An inherently bifunctional subset of Foxp3+ T helper cells is controlled by the transcription factor eos. Immunity 38:998-1012
|Divanovic, Senad; Sawtell, Nancy M; Trompette, Aurelien et al. (2012) Opposing biological functions of tryptophan catabolizing enzymes during intracellular infection. J Infect Dis 205:152-61
|Ravishankar, Buvana; Liu, Haiyun; Shinde, Rahul et al. (2012) Tolerance to apoptotic cells is regulated by indoleamine 2,3-dioxygenase. Proc Natl Acad Sci U S A 109:3909-14
|Baban, Babak; Chandler, Phillip R; Johnson 3rd, Burles A et al. (2011) Physiologic control of IDO competence in splenic dendritic cells. J Immunol 187:2329-35
|Makala, Levi H C; Baban, Babak; Lemos, Henrique et al. (2011) Leishmania major attenuates host immunity by stimulating local indoleamine 2,3-dioxygenase expression. J Infect Dis 203:715-25
|Sharma, Madhav D; Hou, De-Yan; Baban, Babak et al. (2010) Reprogrammed foxp3(+) regulatory T cells provide essential help to support cross-presentation and CD8(+) T cell priming in naive mice. Immunity 33:942-54
|Munn, David H (2010) Lineage-specific transcription factors in unexpected places. Eur J Immunol 40:315-7
|Johnson 3rd, Burles A; Kahler, David J; Baban, Babak et al. (2010) B-lymphoid cells with attributes of dendritic cells regulate T cells via indoleamine 2,3-dioxygenase. Proc Natl Acad Sci U S A 107:10644-8
|Ding, Zhi-Chun; Blazar, Bruce R; Mellor, Andrew L et al. (2010) Chemotherapy rescues tumor-driven aberrant CD4+ T-cell differentiation and restores an activated polyfunctional helper phenotype. Blood 115:2397-406
|Baban, Babak; Chandler, Phillip R; Sharma, Madhav D et al. (2009) IDO activates regulatory T cells and blocks their conversion into Th17-like T cells. J Immunol 183:2475-83
Showing the most recent 10 out of 21 publications


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The American pajama brand, P.J. Salvage, is finally coming to Sweden. The brand has been featured in TV shows like "Ugly Betty", "Grey's Anatomy" and "Desperate Housewives". P.J Salvage is a young and modern brand that, instead of focusing on a specific age group, reaches out to people with a certain "state of mind". P.J. Salvage makes amazing night and loungewear in lovely materials, with vivid prints and exciting designs. At Nelly.com UK you'll find flannel pajamas, slippers, dressing gowns, nighties, and a lot more.
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1617 LAKESIDE CIR Park City, UT 84060
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Estimated Monthly Payment$5,051
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1617 Lakeside Cir. combines 2 units into 1 lrg 7-bed/7-bath chateau w/approx. 4,200 sq. ft on 3 levels w/views of 'Big Stick' ski run at Deer Valley. High-capacity boiler w/circulation pumps supplies all 7 bathrooms w/steady hot water. Fully-remodeled w/top-of-the-line materials. Hardwood floors, carved wood cabinets, marble counters & custom floorplan. 3rd level has 2 bedrooms plus master suite w/spa bath, steam shower, copper fixtures, custom tile & jetted tub. 2nd level has plenty of space for family & guests in the great room w/fireplace & wet bar, gourmet kitchen, formal dining for 12 & living room. Hand-carved mantel & grand staircase. There is a warrantied, over-sized elevator w/back-up battery. Ground level has 4 bedrooms, laundry w/a front-load washer & dryer and a stackable washer & dryer, plus 2 (2-car) garages & covered patio. Lakeside condos are at the base of Deer Valley on bus route or just walk to lifts or tram. Amenities incl. hot tub, pool, shuttle service, & more.
Interior Features Include:
Alarm: Fire, Alarm: Security, Bar: Wet, Bath: Master, Bath: Sep. Tub/Shower, Dishwasher: Built-In, Disposal, Jetted Tub, Oven: Double, Range: Gas, Vaulted Ceilings, Instantaneous Hot Water, Granite Countertops
Basement Full, Walkout
Fireplaces 1
Air Cond: Central Air: Electric
Heating: Forced Air, Gas: Radiant
Floor Type: Carpet, Hardwood, Travertine
Exterior Features Include:
Balcony, Basement Entrance
Acreage: 0.0100 Acres
Lot: See Remarks, Road: Paved, Sprinkler: Auto-Full, Terrain: Flat, View: Mountain
Landscape Landscaping: Full
Roof: Asphalt Shingles
Exterior: Cedar/Redwood
Patio/Deck: 0 Patio 1 Deck
Garage/Parking: See Remarks, Attached, Opener
Driveway Asphalt
Garage Capacity: 4
Other Features Include:
Subdivision: LAKESDIE
Inclusions: Alarm System, Ceiling Fan, Dryer, Gas Grill/BBQ, Microwave, Range, Range Hood, Refrigerator, Washer, Water Softener: Own, Window Coverings
Amenities: Cable Tv Available, Cable Tv Wired, Sauna/Steam Room, Swimming Pool
Water: Culinary
Utilities Gas: Connected, Power: Connected, Sewer: Connected, Sewer: Public, Water: Connected
Storage Garage
Taxes 9239
School District: Park City
Information deemed reliable but not guaranteed accurate. Buyer to verify all information.The multiple listing information is provided by Wasatch Front Regional Multiple Listing Service, Inc. from a copyrighted compilation of listings. The compilation of listings and each individual listing are © 2014 Wasatch Front Regional Multiple Listing Service, Inc., All Rights Reserved. The information provided is for consumers, personal, non-commercial use and may not be used for any purpose other than to identify prospective properties consumers may be interested in purchasing.


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Ambra's soothing jacquard pattern of flowing vines is woven in a combination of Egyptian cotton and silk to create subtle luster and sheen. The neutral hues add a tranquil finishing touch.
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Heidi Klum dropped by the Winter Television Critics Association to talk "Seriously Funny Kids," her new Lifetime show exploiting kids' natural proclivity for hilarity.
"It's really a show for adults," she says. "The kind of things that are funny to grownups."
In fact, the supermodel and "Project Runway" host says there's very little she wouldn't do to make us laugh.
"We thought of a hodgepodge of things," says Klum. "We do so many things. If you watch one week, you don't know what you're going to get in the next."
Here are 5 things Klum says she does to make us laugh:
1.) Interview a dozen or more kids until she finds a gem: "It doesn't always work," she says. "I interview 12 to 13 kids a day. Sometimes, nothing happens. When we pre-interview them, they're really fun and outgoing. But, they get on our set and clam up."
2.) Fulfills kids' dreams: For example, she tells us that she blows an unsuspecting 6-year-old boy's mind with a visit from his favorite basketball player.
3.) Sacrifice her own giggles: "It's hard for me not to crack up," she says. "I have to keep a straight face, because I don't want to let them know it's a joke."
4.) Impersonate a goldfish: Klum tricks a few kids when she disappears from the room and then returns via the voice coming from a nearby goldfish. "If these flowers could talk," says executive producer Eric Schotz, pointing to the arrangement on stage. "Four-year-old kids would talk to them."
5.) Sport a fake booger: "I had a gigantic snot fit," she says. "We had all these different boogers we had to choose from. The kids are looking at me and they don't know what to do. They can't believe what I have coming out of my nose!"
Since the show doesn't premiere until Feb. 1, Klum's unsure if she'll always be up for anything to make us laugh. "We'll see afterwards how you feel about the big booger," she jokes.


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|"Erwan de FERRIERES (Updated) (JIRA)" <j...@apache.org>
|[jira] [Updated] (OFBIZ-4644) Sub-Project Phase are listed in Project Task list
|Wed, 04 Jan 2012 21:53:39 GMT
[ https://issues.apache.org/jira/browse/OFBIZ-4644?page=com.atlassian.jira.plugin.system.issuetabpanels:all-tabpanel ] Erwan de FERRIERES updated OFBIZ-4644: -------------------------------------- Summary: Sub-Project Phase are listed in Project Task list (was: Sub-Project Phase are list in Project Task list) > Sub-Project Phase are listed in Project Task list > ------------------------------------------------- > > Key: OFBIZ-4644 > URL: https://issues.apache.org/jira/browse/OFBIZ-4644 > Project: OFBiz > Issue Type: Bug > Components: specialpurpose/projectmgr > Reporter: Olivier Heintz > Assignee: Erwan de FERRIERES > Priority: Minor > Attachments: OFBIZ-4644.patch > > > To show the problem, add "Demo Project2 Cust2" as sub project for Demo Project1 Cust1[9000] and after go to Project Summary. > In Tasks List, Project2 phase 1 and 2 are list. > To correct the problem, I have add workEffortTypeId as field in view ProjectAndPhaseAndTask and add a constrain on Phase Type (it's not possible to constrain on TASK, because there are multiple Task type) > {code} > + <entity-condition> > + <condition-expr field-name="workEffortTypeId" entity-alias="WEPH" value="PHASE"/> > + </entity-condition> > {code} -- This message is automatically generated by JIRA. If you think it was sent incorrectly, please contact your JIRA administrators: https://issues.apache.org/jira/secure/ContactAdministrators!default.jspa For more information on JIRA, see: http://www.atlassian.com/software/jira
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The City of Alexandria Office of the Arts is accepting proposals for the temporary placement or experience of art in public spaces in the City of Alexandria through the Special Opportunity Grant program. Artists and artist teams can apply for grants up to $5,000. The deadline to submit proposals is April 18, 2014 at 5:00 p.m.
This grant is open to artists 18 year of age and older who reside in the Greater Washington Metropolitan region for at least one year prior to the application. The project must be completed by September 30, 2014.
A grant workshop/webinar on Tuesday, April 1 at 7pm at the Lee Center, 1108 Jefferson Street, Alexandria, VA 22314. To attend via the webinar please register in advance by email to firstname.lastname@example.com.
The Special Opportunity Grant's intention is to encourage innovative, thought-provoking projects that relate to a proposed space or spaces in an engaging way. All artistic disciplines will be considered including, but not limited to: visual art, storytelling, poetry, spoken word, dance, music, theatre, performance art, and new media. The project should foster community participation in and an understanding of public art projects.
One project will be awarded in each of the City's three planning districts: Old Town, Del Ray/Arlandria, and the West End. More than one location or planning area in the City of Alexandria may be proposed. Traveling or rotating project sites will also be considered. Projects are to be in areas accessible to the public. Based on the proposal, City permits or project modifications may be required. The Office of the Arts will work with the selected artists or artist teams to facilitate the process.
Submission Requirements
Proposals may be submitted via email to email@example.com or delivered to Durant Arts Center, 1605 Cameron Street, Alexandria, VA 22314. All proposals must be received by the deadline and must include:
- Written Description of proposed project. Please include: project concept, process, timeline, itemized budget, site specificity, installation method and anchoring procedures (if applicable), plan for community engagement, value of the project to the community, and measurements of the project's success
- Not to exceed two pages, 12-point Arial font, 1" margins
- Resumes and Contact Information for artist or artist teams
- Work Samples and Descriptions: images, CDs, writing samples, video clips or portfolios
Friday April 18, 2014, 5:00pm
- Only individual artists or artist teams are eligible
- Artists may submit up to three different proposals
- Artists may submit existing art for consideration
- Not eligible: current members of the Alexandria Commission for the Arts and its subcommittees, City of Alexandria Employees
Evaluation Criteria
- Benefit to the City of Alexandria: the level of community participation and engagement of the project
- Artistic excellence
- Experience of the artist/artist team (emerging artists are encouraged to apply as a team)
- Innovation of project
- Quality and clarity of proposal
- Suitability to the proposed site
- Safety
- Explanation of how community involvement will be achieved.
Grant Requirements
- No ticket sales or fees may be charged
- All events and installations must be freely accessible
- Matching funds are not required
- Artist or Artist Team will be responsible for any and all maintenance or repair during the project
- The winning artists will permit the Office of the Arts to promote their projects in all media including, but not limited to, press releases, web sites, and social media.
- A final report must be submitted to the City of Alexandria Office of the Arts within one month of the conclusion of the project and no later than September 30, 2014


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Sweden Shows Europe How to Cut Debt, Weather the Recession: View
Sweden faces a difficult year, like every other European economy, but unlike the rest of the European Union, it's equipped to cope. There are lessons here, especially for the EU's other non-euro countries.
Scandinavia's biggest economy will see growth slow to less than 1 percent in 2012, down from an impressive 4.5 percent in 2011, according to the National Institute of Economic Research. Sweden relies heavily on exports to the rest of Europe, and the EU's protracted economic crisis will set it back.
Shortly before Christmas, the Riksbank cut its benchmark rate for the first time since 2009 to 1.75 percent. The NIER predicts further reductions this year in response to a weaker economy and slower inflation. This prospect underscores the seriousness of the situation -- and how valuable it is at such times to have an interest rate to change.
The value of monetary independence is the first and most important Swedish lesson. Sweden stayed out of the euro system when the currency was introduced in 1999, and in the past several years, the government has used this monetary flexibility to the full.
Firm Fiscal Hand
With most of the EU bound by the European Central Bank's excessive monetary caution, the Riksbank cut interest rates more sharply than the ECB and (in real terms) the U.S. Federal Reserve from 2007 to 2009. Its inflation-adjusted interest rate fell from 2.25 percent to minus 1.5 percent. The central bank also devised new credit facilities and other unconventional measures to support the Swedish financial system.
Fiscal policy played a smaller role in steadying the economy. This, too, was a legacy of the 1990s, when budget deficits widened and a national consensus formed around the need to curb government spending and stabilize the public finances. Sweden's subsequent success in doing that is nothing less than remarkable.
Hence Sweden's second lesson: Fiscal stimulus isn't a necessary condition for economic recovery. Through the course of the recent recession, the government's cyclically adjusted budget stayed in surplus. As a result, Swedish government debt stands at less than 40 percent of gross domestic product, among the lowest of any rich country.
Fiscal policy still helped to cushion the recession and support a recovery -- not with discretionary stimulus, but through so-called automatic stabilizers, which are relatively strong in Sweden. (Measures such as consumption taxes and generous unemployment benefits relax fiscal policy in recessions and tighten it in booms, even if policy stands pat.)
In Sweden's case, a firm fiscal hand, far from stifling the recovery, probably helped it along. Keeping the budget under control buoyed consumer and investor confidence. Surging demand for Swedish debt drove bond prices higher last year; indeed, Sweden's government pays less to borrow than Germany's.
Should others follow its example? For one group, the answer is plainly yes. Members of the EU that have not yet adopted the euro are nonetheless committed in principle to doing so. (This includes Sweden; the U.K. and Denmark are two exceptions.) Sweden proves, if further proof were needed, that euro membership is a mistake.
Lacking a currency to devalue and interest rates to cut, members of the euro system would only worsen their recessions if they squeezed fiscal policy as tightly as Sweden did. Beyond the EU, though, Sweden does suggest that sufficiently powerful monetary easing can carry most, if not all, of the burden of economic stabilization.
New Swedish Model
Models have their limits. Every country has to cope with its own special circumstances. It helped Sweden that the most recent slump, unlike that of the 1990s, was export-led: Its exports are capital-intensive, so a drop in foreign demand raises unemployment by less than a decline in demand at home. It also helped that since coming to power in 2006, the country's center-right coalition government has made private-sector job creation a priority.
Note, therefore, that this isn't the old Swedish model. Taxes on labor have been cut and the country's once-lavish welfare state is being squeezed.
What do Sweden's voters, who once elected left-wing Social Democrats by default, make of that? Their economic concerns have increased lately, but few blame Prime Minister Fredrik Reinfeldt and his government, and the Social Democrats have failed to recover.
This suggests a third lesson, political rather than economic: Fiscal conservatism can be popular. Sweden is reluctant to put its hard-won fiscal strength at risk. Rightly so. Sweden is better placed than most to deal with the further economic setbacks the EU seems determined to dispense. More interest-rate cuts and a shift to budget stimulus, if needed, are options that few other rich economies have.
To contact the senior editor responsible for Bloomberg View's editorials: David Shipley at firstname.lastname@example.com.


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Pats call in for Collins
Belichick dials up true pass-rushing threat
Credit: AP (File)
FOXBORO — The Patriots added some explosion to their defensive edge last night when they made their first selection of the NFL draft.
They selected Southern Mississippi outside linebacker Jamie Collins with the 52nd pick, and they might have found a little extra punch to attack quarterbacks in the upcoming season.
The 6-foot-3, 250-pounder had 21 sacks, 45 tackles for loss, seven forced fumbles, three interceptions, two fumble recoveries, three defensive touchdowns, 18 passes defensed and 314 tackles in four collegiate seasons.
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Maine, USA
Vintage Little People
J.A. Pingree brings "Vintage Little People" to life through her art and products. Though creativity and humor, these individual pieces of art display "Vintage Little People" in a new way.
Art & Products By J.A. Pingree
**8.5" x 8.5", perfect binding, white interior paper (80# weight), full-color interior ink, white exterior paper (100# weight), full-color exterior ink
Copyright © J.A. Pingree Enterprising Privacy Policy
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VBScript (.vbs file) To run a macro in an excel in predefined intervals
This project was awarded to furqanshakoor for $30 USD.Get free quotes for a project like this
Project Budget$30 - $40 USD
Total Bids7
Project Description
I have a macro written in an Excel . I want you to write a VB Script to create a ".vbs" file which can make the macro run in the Excel in predefined intervals. I have written a code, but its not returning me exactly what I need. I can share the sample VBS file and the Excel file to interested person. I think this will not take more than an hour for a person who is good in VBS scripting or any other windows scripting.
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Par Amnesty International, 21 octobre 2011, N° d'index: MDE 14/041/2011
The death sentences of 53 people, including five foreign nationals, were ratified by the Iraqi presidency on 20 October. They are at imminent risk of execution.


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Friendly staff, clean room, clean bathroom, pretty up to date, close to attractions. No personal valuables safe in room clean but extremely small fitness nook/room
Stay was Awesome Excellent Customer Service!!!! I liked how when I called Front Desk about not having a microwave and how it said my room included microwave I was informed that it was available upon request and one would be delivered to my room right away and literally as I hung up phone I received a knock at the door that microwave had arrived and they set up. Great friendly staff!!!!
From the moment I walked past the glass door and into the Lobby area I was in love with the decour. The lobby area was beautiful and spacious. There was a snack room dining tables to our left and a bar/ restaurants right there. Once you continue to walk further into the Lobby you'll notice there is a computer area which all guests area allowed to use to surf the web or print. Next to that was more seating areas. There was a beautiful fire place area outside that was surrounded by comfortable seats. There is a big pool and jacuzzi. The bed was super comfortable and I loved the water pressure in the shower. Moreover, it is near everything so it was very convenient. It's surrounded by Medieval Times, Knotts Berry Farm, The Bodies Exhibit, Restaurants, The mall is down the street, etc... The outside of the Hotel was dirty. There were a lot of leaves everywhere in the driveway area. This needed some serious cleaning As soon as I walked into the Hotel my opinion changed however. The rooms were a lot smaller then the pictures showed. Our room did not have a balcony which upset me but we did arrive before our check int time so maybe that was the reasoning behind that. The jacuzzi and the gym were in tiny rooms and everytime I intended to go into either one it was crowded. They only gave us 3 towels.
Close to tourist spots Coming from the south must make a u-turn on busy street to enter parking lot.
Loved the location. Literally right next door to knotts berry farm and there was a mall across the street as well. Staff was awesome and rooms were super CLEAN. That's all I could ask for. The souvenir shop was never open.
Rooms could have been cleaner especially bathroom and tub. Construction to balcony incovenient to getting to the room. and really no wear to put the clothes unless you hung some of them.
Location only The room stated non smoking and the room smelled like smoke horrible review
Clean and spacious Thicker bed comfortable, refrigerator, and updated TV with more channels
The bed was comfortable. There was no comforter on the bed, instead there was a warm blanket between 2 sheets. I really liked that, knowing that hotels are not required to wash their comforters. The walls were thin and could here the people next door getting busy at 4 in the morning. The shower was AWFUL, there was no pressure, midway through the shower I was ankle deep in water, half of the pressure was coming out of the faucet rather than the shower head and the shower head was old and crusted over with calcium. The breakfast was lack luster
I was left alone. I tried to shorten my stay due to an emergency and had to cut a day; your staff basically told me oh well, too bad.
Breakfast was great employees were nice and courteous the rooms were clean and parking was easy and right in front of my room What i didnt like was the tv it was outdated and the cable sucks got like 8 channels terrible
Staff is always nice. Rooms are always neat and clean. Very good facility and stay for the price. Sometimes things are broken. On this particular stay, the tub faucet dripped water when it was off, the tub drain cover was detached, and one of the outlets (the most important one by the bed) didn't work. I know they just remodeled the rooms here, which they look nice, but they should've added those lamps with the outlets on there.
Rooms were clean, large, & sparse. Wifi was very slow.
Nothing this place is gross and the grounds are dirty and broken down Rooms are dirty tv's are old and broken changed my room 3 times pictures are fuzzy and the screen is green I didn't feel safe staying there the maid kept coming in the room for no reason
I didn't like the hidden fees upon check in.
It was comfortable, clean and spacious. It was reasonably price for being so close to Knotts Berry Faem & Disneyland!! N/A
The closeness to the theme park which we visited in our trip. It was literaly a walk away.
it was clean and quiet and close to knotts berry farm. breakfast menu was a bit sparse.
The only reason why I stayed after seeing the room is because I didn't want to lose my money. I did not feel safe at this place. The carpets were not cleaned it appeared, for years.
I liked that the room was clean and had a refrigerator and microwave. I did not like that there were mattresses outside the lobby. It made my first impression of the hotel very bad. Also, the staff were not friendly when checking in or asking questions and I was ignored a few times.
Only that it was close to Knotts .... The entire stay was terrible, noisy, dirty, smelly, and not very pleasant totally
the convenience of the location to other businesses in the area the claim of wireless internet access I could not access
I liked the cleanliness of the room and the pool and hot tub. Everything was very clean. I did not like the service, day time was very unprofessional and after hours/owners were not friendly. We called ahead to request flowers etc be brought in, and the answer wasn't even, "can we give you some phone numbers for delivery?" The answer was, "no. We don't do that." Not how we anticipated spending our 7th anniversary.Also their afterhours security gate has a metal tab sticking outinto the hallway... Not highlighted, and is actually the same color as the wall... In any case I now have a deep bruise and near fracture on my hand because I didn't see it, and walked right into it.
Nothing at all!!! Oh wait maybe that it was 10 miles away from the beach. Oh yes I did not like any of the staff they were very rude and did not understand half of anything you said. ALso the manager (rude) gave out my room key I guess they thought we had checked out? Lol who knows but we were only there a day and reserved two nights. They just gave our key to some random people and it just so happend my lap top got stolen right along with my purse. But thank god the cops came let us watch cameras and just happend to catch that the people were still staying in the hotel and got our stuff back. After spending three hours looking at cameras on my vacation! So if you want the staff to just give your room key out and let your personal belongings get ransacked threw you go ahead and stay there! K! I will never go back
The location is great. Directly across from Knotts Berry Farm and only 6 min away from Disneyland! The hotel in general looks old and rundown. There were a couple of roaches in the room. The pillow cases smelled of cigarettes. Housekeeping refused to change the pillow cases. There was only 1 pillow per queen size bed. When we requested additional pillows we were given 1 for each bed. Pillows were flat and old. All in all I would not stay there again.


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Non-Invasive Body Contouring
Lose your excess body fat without dieting.
Slim Your Core offers the most advanced technology in body contouring. Our 15 minute treatment quickly and naturally causes the fat cells to open and empty out.
Where does the fat go?
The fat cells open and release the contents (triglycerides) into the interstitial space (the space between cell membranes). The lymphatic system is responsible for transporting fatty acids to the circulatory system for metabolism and is 'powered' by muscle movement. Using our vibration machine after your 15 minute treatment will help activate your lymphatic system and eliminate the toxins and waste naturally.


text: OverviewBack to top Abra Therapeutics - Bubble Bath Mental Clarity - 14 oz. Item# :55465UPC# :021204140040 Brand:Abra Therapeutics Size/Form:14 oz. MENTAL CLARITY helps you think clearly and choose wisely. Clear your busy mind. Keep your thoughts focused with clarifying Lemongrass, Grapefruit, Tangerine and Rosemary essential oils. Enjoy Mental Clarity Aromatherapy Bubble Bath whenever you need some time to make an important decision or gain perspective on a troubling situation. Think clearly. Choose wisely.


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- PT. Mabar Elektrindo
- 0 reviews
- 0 gaji
- Journal entry
- Prepare monthly financial statements
- Coordinate with auditor
- Prepare and submit reports to official external parties
- Prepare and submit tax return
- Other jobs as required
- Must have a Bachelor Degree in Accounting with maximum age 35 years old;
- Min. 4 YEARS EXPERIENCES as AN ACCOUNTANT @Dept. Finance & Accounting in foreign company;
- Fluent English, prefer Mandarin;
- Indonesia Citizen;
- Familiar with Indonesia Accounting Standards and Tax Law;
- Accuracy in daily work and other projects;
- Responsible;
- Discipline;
- Ability to meet communicated schedules and deadlines;
- Ability to maintain good working relationships with superiors and other employees;
- Ability to function as a team player;
- strong Computer Skills.
If you feel that you can meet the qualification and up to the challenge, please send your complete application (application letter, resume, expected salary and any related supporting documents) and current color photograph at size 4 x 6 cm by clicking button bellow
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Deskripsi Perusahaan
PT. MABAR ELEKTRINDO (hereinafter refer to"company") is a joint venture company, the biggest shareholder is China Oceanwide holdings group (http://en.chinaoceanwide.com/).
The company main business is invest, construct and operate coal fired power project.


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25% off mugs, totes, and spiral notebooks. Use STRETCHFOR25
Watercolor painting I did shortly after Favre was traded away by the Packers ending his career with the Pack.Original size 9″ × 12 FEATURED IN MONOCHROME IN COLOR GROUP "Please visit My Bubble site
favre packer packers green bay football watercolor dan wagner
Wonderful image, Dan! Love your paintings.
Thank you Lynne, you are too kind as always.
Congratulations!! You have been featured in the Monochrome in Color group (clickable banner)
Please check out our Challenges
Thank you Cee!
Wonderful work,….Lot of emtion inthis image,…..I believe the Pack has found new Gold,….
Thanks John, yes I admit and am thrilled Rogers is very, very good. The new gold. Very fortunate to have two very magnificent QBs in a row.
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Politics, Gender and Concepts
Theory and Methodology
Edited by Gary Goertz Amy G. Mazur
Format: Paperback
Normal Price: $67.95
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Politics, Gender and Concepts by Gary Goertz
Book DescriptionA critique of concepts has been central to feminist scholarship since its inception. However, while gender scholars have identified the analytical gaps in existing social science concepts, few have systematically mapped out a gendered approach to issues in political analysis and theory development. This volume addresses this important gap in the literature by exploring the methodology of concept construction and critique, which is a crucial step to disciplined empirical analysis, research design, causal explanations, and testing hypotheses. Leading gender and politics scholars use a common framework to discuss methodological issues in some of the core concepts of feminist research in political science, including representation, democracy, welfare state governance, and political participation. This is an invaluable work for researchers and students in women's studies and political science.
Buy Politics, Gender and Concepts book by Gary Goertz from Australia's Online Bookstore, Boomerang Books.
Book DetailsISBN: 9780521723428
(247mm x 174mm x 17mm)
Pages: 322
Imprint: Cambridge University Press
Publisher: Cambridge University Press
Publish Date: 13-Nov-2008
Country of Publication: United Kingdom
Other Editions...
Books By Author Gary Goertz
Puzzle of Peace, Hardback (March 2016)
The Puzzle of Peace moves beyond defining peace as the absence of war and develops a broader conceptualization and explanation for the increasing peacefulness of the international system.
Tale of Two Cultures, Paperback (September 2012)
Some in the social sciences argue that the same logic applies to both qualitative and quantitative methods. This title discusses major differences between these two traditions that touch various aspects of social science research, including design, goals, causal effects and models, concepts and measurement, data analysis, and case selection.
Politics, Gender and Concepts, Hardback (November 2008)
Provides a systematically gendered approach to methodological issues in political science.
Explaining War and Peace, Paperback (June 2007)» View all books by Gary Goertz
Focuses on the use of 'necessary condition counterfactuals' in explaining two key events in twentieth century history, the start of the First World War and the end of the Cold War. Containing essays by leading figures in the field, this book analyzes the causal logics of necessary and sufficient conditions.
» Have you read this book? We'd like to know what you think about it - write a review about Politics, Gender and Concepts book by Gary Goertz and you'll earn 50c in Boomerang Bucks loyalty dollars (you must be a member - it's free to sign up!)
Author Biography - Gary Goertz
Gary Goertz teaches political science at the University of Arizona. He is the author or co-author of seven books and over forty articles on issues of international politics, methodology, and conflict studies, including Contexts of International Politics (Cambridge, 1994). Amy G. Mazur is Professor in the Department of Political Science at Washington State University. Focusing her research on comparative feminist policy issues, she has published numerous book chapters and articles and is author or editor of four books, including Theorizing Feminist Policy (2002).
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Call our experts: 888.808.FINE
Custom Stationery from luxury designers!NEW! Wedding Invitations Customize any Address Stamp to match your style!
Select a quantity and printing method. Changes are easily made later.
This white sticker with a pink border features a palm tree at the top.Colors in the design on the sticker include: pink, brown, black, white and green.


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Added reply in a thread Reed Monster Tweet 12/6/2016 2:42 PM
Holy shit that just made my mouth water! Gonna have to get one of those for New Years eve now.
Added reply in a thread Put a fork in JS7 5/21/2016 8:42 PM
I feel bad for James Stewart when he hits 50-60 years old. All of these injuries are going to take their toll. Plenty of other riders will be in the same position, but a lot of them didn't make the money that he did where he could have just walked away ... more »
Added reply in a thread any straight edge mx riders? 4/5/2016 5:40 PM
God dammit..I knew there were two "A's" and still typed it wrong. Guess I was being too high and mighty with the spelling correction attempt...Fuck me.
Added reply in a thread any straight edge mx riders? 4/5/2016 5:23 PM
Because dude spelled McKaye.."Mcaye"?.....HA!
Added reply in a thread any straight edge mx riders? 4/5/2016 4:51 PM
On Thursday April 7th, it will be 21 years since I was introduced to the idea of the drug and alcohol-free punk movement called straight edge. In those 21 years: I've never beaten anyone up I've never "preached" my "lifestyle" onto others I've seen countless ... more »
Added reply in a thread Age old question 1/30/2016 5:40 PM
Sotille's fastest lap was more due to local knowledge and track conditions early in practice, it hadn't really turned to shit at that point. Southwick has always been a place where locals stood a decent chance when the mx series rolled into town.
Added reply in a thread FOR SALE :: Fox V3 Star Wars Helmet 12/17/2015 8:49 AM
I didn't think of that! Totally worth it
Added reply in a thread FOR SALE :: Fox V3 Star Wars Helmet 12/17/2015 5:17 AM
Shipping: $273.11 What bargain!
Added reply in a thread spoke with my wallet: rmz edition 12/5/2015 4:01 AM
He spoke with his wallet. He doesn't give a shit about buying a two-stroke.
Added reply in a thread Mike Tyson Studied Old Fights (Anaheim 82) 12/3/2015 9:36 AM
Great race, great video. That track looks like it would be so fun to ride!. Makes you appreciate how far the suspension technology has come too.
Added reply in a thread Reed trolling? 11/5/2015 3:35 AM
Could it be that he's just simply referring to the fact that no more Two-Two Motorsports race team means his connection to Discount Tire is in a limited capacity? I can't imagine the individual sponsorship they provide would be cause for the same level ... more »
Added reply in a thread Canard for the win bitches! 10/17/2015 5:17 PM
Everyone agrees...Oh wait...This isn't the break between moto 2 and 3 of the 2014 MEC........
Added reply in a thread Mika Musquin, what an amazing attitude! 10/14/2015 8:01 PM
Sad, but also inspirational. This reminded me of when Martyn Ashton was paralyzed a couple years ago, it bums me out so much when accidents like this happen. Puts things in perspective when someone is so positive after encountering such a life-changing ... more »
Added reply in a thread Things I have learned on Vital so far this year 6/25/2015 4:35 AM
35. That was a shitload of typing for people to just make fun of you
Added reply in a thread Dungey Passed 14 riders in 1 lap 6/8/2015 5:35 PM
I passed 60 riders in 1 lap... In a 30+ cyclocross race.
Added reply in a thread Never Leave Your Bike Alone 5/26/2015 4:35 PM
"Never leave your bike alone"..A good friend of mine left his bike alone and something happened to his engine as well. He realized something was wrong after we arrived at the track that weekend.
Added reply in a thread "New" 2007 CR250R For Sale - Craigslist 5/23/2015 4:52 PM
I don't even think that price is within reason for a collector...For those who said they want to ride their bikes, you could easily find a used one and throw a ton of cash to restore/modify it and have a better bike for the same money as this nutcase ... more »
Added reply in a thread Will Tomac be the next GOAT? 5/19/2015 2:55 PM
Added reply in a thread Will Geico resign ET? 5/18/2015 6:18 AM
Let me give you a glimpse of the future using the past.. Will KTM resign Ken Roczen? Or do you think another team like Suzuki will sign him
Added reply in a thread Wheelie boy scum in the uk 5/5/2015 3:21 PM
This is going to sound racist as hell but bear with me...Can every black dude worldwide just hop on a bike and totally rip bad-ass wheelies or what? I mean seriously. I'm not jealous they are doing them on potentially stolen bikes, but I am jealous because ... more »


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App Creation for iPhone and Android from existing Magento website
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Project Budget$250 - $2500 USD
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Project Description
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You are here:Home > Guidance centre > Improving your governing board > Effective Governance > Skills Audit and Matrix
NGA encourages all governing bodies to use a skills audit to help them identify any skills and knowledge they still need to deliver their functions effectively. This updated 2015 version of the NGA skills audit is structured around the core functions of the governing body, as defined in the Governors' Handbook:
This is to enable governing bodies to ensure they have sufficient expertise to carry out their core duties effectively. However, it is also important for governors to know their school and community, so skills relating to this are also included.
An individual governor is not expected to have all the skills listed in the audit, but they should be covered across the governing body. To make it easier to get a view of the skills across the governing body as a whole, we've also produced a skills matrix, which can be used to collate governors' responses from the skills audit. The matrix is colour coded so it is easy to identify areas of particular strength (green) or weakness (red).
Download the skills audit
Download the skills matrix
Please note that you will need Adobe Reader to view the skills audit. You can download the latest version free of charge here - http://get.adobe.com/uk/reader/otherversions/


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Keeping My Clothes Smelling Fresh
Five Tips for Cleaning a Reusable Coffee Filter
If you use a reusable mesh filter with your coffee machine, you need to clean the filter on a regular basis. Keeping it clean safeguards flavour and ensures it works correctly. Wondering how to clean it? Take a look at these tips: 1. Boil filter in vinegar and water. Over time, coffee grounds get stuck to your filter, and an oily residue from the coffee grounds may also build up on it. To effectively remove those items, boil a solution of two parts vinegar and one part water. Submerge your filter and let it soak in the bubbling liquid for...read more
The Array of Choices for Laundry Sink Installation at Home
With many commercial and industrial buildings, an almost certain find in the utility rooms is a laundry tub, or laundry sinks as they are commonly called. These tubs differ from your ordinary home sink by their sheer volume of allowance and large sizes that make them suitable for carrying out heavy duty washing activities in the areas. The wide and deep basins would certainly be quite handy in handling activities such as washing gardening equipment, hand-washing your bulky laundry, bathing your beloved pet, or even simply emptying the mop...read more
Maintenance Tips You Need to Keep Your Washing Machine in Good Condition
For your washing machine to serve you properly, you must take good care of it. Just like many other appliances in your house, failing to maintain your washing machine elevates the risk of a breakdown and eventual costly repairs. Essentially, the washing machine relies on an electrical power supply, hot water inlet, cold water and detergents to perform its functions. If you have just bought one for the first time, the following are some of the maintenance tips that you can use to keep the machine in good condition: Do Not Overload the Machine...read more
Signs of Impending Ducted Heating Repairs
Ducted heating systems are units that are commonly found in both residential as well as commercial buildings. They are preferred due to their convenience as well as durability. However, just as most other appliances, these HVAC systems require proper and regular maintenance to ensure they remain in optimal working condition. Not taking the right maintenance measures will lead to the eventual decline of your heating system. The following are some of the signs impeding ducted heating repairs. The ducted heating system is not heating the...read more
Monthly Fire Extinguisher Safety Checklist For Small Businesses
It's important for the safety of your employees, and for that of your business premises, that you have your fire extinguishers serviced by a professional appliance services company on an annual basis. However, it's also important that you give your extinguishers a monthly visual check to ensure that they are in good condition. Here's a helpful guide on what you need to do. Fire extinguisher safety check guide Begin by looking at the position of your fire extinguishers to see if anything in their location has...read more
Guide to Buying Refrigerated Cabinets for Commercial Applications
Refrigerated cabinets offer a suitable storage space for food products that need to be kept refrigerated in commercial areas such as supermarkets, hotels, restaurants, bakeries, grocery stores and so on. There are several varieties of refrigerated cabinets that you can choose from, making the decision to settle on a particular type of cabinet rather difficult. Here are a number of important things you should consider to ensure that you choose the most appropriate refrigerated cabinets for your intended commercial application. Temperature What...read more


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Catalogue Number: HW5-ZF3B
- Author: Ian Rankin
- Format:Paperback
- Publisher:Orion Publishing Co
- Published:19 February 2009
Sorry, there are currently no sellers for this product.
Product description
- Total Pages: 128
- Genre: Crime & mystery
My dad used to say to me, 'Try to keep a cool head and a warm heart'. At least I think it was my dad. I don't really remember him. Gravy worked in the graveyard - hence the name. He was having a normal day until his friend Benjy turned up in a car Gravy didn't recognise. Benjy had a bullet hole in his chest, but lived just long enough to ask Gravy to hide him and look after his gun. Gravy had looked after things for Benjy before, but never a gun. When Gravy looked in the car he found blood, a balaclava and a bag stuffed with money. Gravy's not too bright but he wants to help his friend. So Gravy finds himself caught up in the middle of a robbery gone wrong, a woman who witnessed a murder, and some very unpleasant men who will do anything to get back the money Benjy stole...
Author's Biography
Ian Rankin is a regular No.1 bestseller, and has received numerous awards, including the prestigious Diamond Dagger. He lives with his family in Edinburgh, and in 2003 received an OBE for his services to literature.


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The rustic casual design of this two-tone occasional table set provides versatile style to any living area. The rectangular coffee table and two square end tables each feature a grooved plank style top in a medium finish. The solid wood legs and corner braces are finished in a dark brown finish for contrast.Dimensions:End table (2) 23.63" x 23.63" x 23.00"Cocktail table 47.75" x 23.63" x 18.00"
The Latoon 3-Piece Occasional Table Set in Two-Tone Finish with Plank Style Tops and Solid Wood Legs by Signature Design by Ashley from Wayside Furniture. We proudly serve the Akron, Cleveland, Canton, Medina, Youngstown, Ohio area. Product availability may vary. Contact us for the most current availability on this product.
Nothing on this page may be copied or reproduced without explicit permission.
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Good ole Aglaonemas used to be THE houseplant way back when, and they went
out of vogue for
years. They're now making a strong commercial comeback in the form of
hybrids created by Dr. Frank Brown of Valkaria Fla. But even the 'old' ones
make wonderful houseplants, and in my opinion are well worth the space in an
Aroid collectors greenhouse. Interest has seriously waned for this and
other genera among Aroiders, in favor of the tuberous Amorpho's and company.
I've been looking for years for many of the old ones, such as 'Francher',
'Malay Beauty', 'Pewter', 'Belvedere', the many forms of costatum,
'Mutton-fat Jade', 'San Remo', the many forms of crispum, 'Nocturne', etc,
etc, etc.
'Treubii' is only occasionally seen here in stores among displays of 'Silver
Queen' and Brown's hybrids, along with an 'Elegans' very rarely. I'm sure
many of these antiques exist in small numbers in various collections.
An excellent old softback book for newby's wanting to learn about Ag's and
their history is the 'Aglaonema Grower's Notebook' by Roy N. Jervis, 1978,
80. It's magazine size, and only black and white, but is a
wealth of information on this genus about which little has been written.
It's probably difficult to find. Most interesting is the natural 'hybrid
swarm' found by chance on Luzon, Philippines in1980, and Dr Brown was guided
to this find shortly afterwards. These were not just a few plants from a
chance cross, but hundreds of plants in a ''giant 'hybrid swarm' of more
complex parentage and background''.
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Ryan Lemmon Showcase baseball tournament this weekend
The Ryan Lemmon Foundation's annual Senior Showcase event will take place this Friday and Saturday at Windrow Park.
The showcase is now in its 17th year and has grown to be one of the best postseason events on the West Coast.
There are two games on Friday and two games on Saturday, with a home run derby in between games each day.
Seniors from the Trinity League will play seniors from the South Coast League at 4:30 p.m. Friday.
A game between seniors from the Century League against seniors from the Sunset League will follow at 7:30 p.m.
On Saturday, seniors from the Empire League will play seniors from the Sea View League at 1:30 p.m. Seniors from the Pacific Coast League will take on seniors from the Freeway League at 4:30 p.m. Saturday.
Showcase games will be broadcast on Cox 3 and Time Warner Cable.
The Pacific Coast League team will include Austin Bourassa, Gilbert Gonzales and Chase Augustus from University, Michael Fuchs, Jake Hazard, Chase Bartholomew, Justin Pearson and Dallas Dey from Beckman, Max Gleit and Cody Tyo from Northwood, Zach Weber, Kai Abe, Connor Rogers and Chad Jacob from Woodbridge and Nick Abrahams from Irvine.
There will also be a sophomore baseball pro workout from 8 a.m. to 2 p.m. on Saturday at Windrow Park.
Local sophomores chosen to participate include Trevor Lawrence, Joshua Lopez and Taylor Cleary from Northwood, Ryan Santa Cruz, Jack Martine, Jake Larson and Aharon Modlin from Woodbridge, William Faure and Neil Boudreau from University, John Lavigne from Irvine and Ryan Carpenter, Jack Wiese, Tyler Guerts and Michael Hanson from Beckman.
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The central theme of Research Project 3 {RP3) is biologic discovery with selective targeted inhibitors of the two signal transduction pathways that are activated most frequently in human cancer: RAS/RAF/ERK and PI3K/AKT/MT0R. Multiple inhibitors of RAF, MEK, P13K, AKT, and mTor are now being developed for the treatment of these tumors. In this proposal. Molecular Imaging (Ml) with PET and MRI w/ill be used as a guide for understanding target inhibition and optimizing these therapeutic regimens. This work is based on recent fundamental studies from our group on pathway regulation and function;effects of inhibitors on components of these pathway;development of Ml modalities for imaging pathway inhibition and tumor response in preclinical models and patients. The recent clinical trial of the RAF inhibitor PLX4032 in melanomas with mutant BRAF was based in large part on our basic findings and resulted in an 85% clinical response rate and serves as proof of principle for the utility of targeting these pathways (NEJM 2010;363:809-19). ERK signaling drives the proliferation of tumors in which it is activated and we have shown that inhibition of the pathway can be imaged effectively with by FLT/PET (Cancer Res. 2007;67:11463-9), In contrast, PI3K/AKT/mTor signaling regulates glucose homeostasis and FDG uptake is very sensitive to mTor inhibitors. These data suggest a role for Ml both as a measure of pharmacodynamic pathway inhibition and tumor response, as well as other changes in tumor biology. For instance, in recent trials, we showed that ERK pathway inhibition induces the iodide transporter and iodine avidity of tumors with mutant BFIAF. The RPS research plan is comprised of the fallowing specific aims. SAl;.Imaging the effects of selective inhibition of P13K signaling in tumors with mutational activation of the pathway. SA2: Imaging the effects of selective inhibition of ERK signaling in tumors with mutant BRAF. SA3: Imaging the effects of combination therapy utilizing inhibitors of P13K or ERK signaling. The major goal of the project is to develop imaging as a tool for measuring the quantitative and temporal effects of targeted drugs on pathway inhibition, tumor biology and tumor growth. The inhibitors we are using are all in or about to enter trials, the major limitations of which are the inability to assess pathway inhibition or to rationally choose combinations, so we expect the findings in this project to be rapidly translated and to have a major clinical impact.
Malignant melanoma, thyroid cancer, colon cancer and breast cancers are known to harbor mutations to key molecules that change a normal cell to a cancerous one. Recently, special drugs which disable only the mutated, cancer-producing molecules have been discovered, and early clinical results are promising. Only a portion of patients respond, and duration of treatment response is relatively short. Molecular imaging after treatment with selective drugs will be used to improve duration of response and chances of cure.
|Cheal, Sarah M; Xu, Hong; Guo, Hong-fen et al. (2014) Preclinical evaluation of multistep targeting of diasialoganglioside GD2 using an IgG-scFv bispecific antibody with high affinity for GD2 and DOTA metal complex. Mol Cancer Ther 13:1803-12
|de Biasi, Andreas R; Villena-Vargas, Jonathan; Adusumilli, Prasad S (2014) Cisplatin-induced antitumor immunomodulation: a review of preclinical and clinical evidence. Clin Cancer Res 20:5384-91
|Vargas, Hebert Alberto; Wassberg, Cecilia; Fox, Josef J et al. (2014) Bone metastases in castration-resistant prostate cancer: associations between morphologic CT patterns, glycolytic activity, and androgen receptor expression on PET and overall survival. Radiology 271:220-9
|Adusumilli, Prasad S (2014) Translational immunotherapeutics: chemoimmunotherapy for malignant pleural mesothelioma. Cancer 120:3268-71
|Eguchi, Takashi; Kadota, Kyuichi; Park, Bernard J et al. (2014) The new IASLC-ATS-ERS lung adenocarcinoma classification: what the surgeon should know. Semin Thorac Cardiovasc Surg 26:210-22
|Zhang, Hanwen; Huang, Ruimin; Pillarsetty, NagaVaraKishore et al. (2014) Synthesis and evaluation of 18F-labeled benzylguanidine analogs for targeting the human norepinephrine transporter. Eur J Nucl Med Mol Imaging 41:322-32
|Cheal, Sarah M; Punzalan, Blesida; Doran, Michael G et al. (2014) Pairwise comparison of 89Zr- and 124I-labeled cG250 based on positron emission tomography imaging and nonlinear immunokinetic modeling: in vivo carbonic anhydrase IX receptor binding and internalization in mouse xenografts of clear-cell renal cell carcino Eur J Nucl Med Mol Imaging 41:985-94
|Zhang, Hanwen; Huang, Ruimin; Cheung, Nai-Kong V et al. (2014) Imaging the norepinephrine transporter in neuroblastoma: a comparison of [18F]-MFBG and 123I-MIBG. Clin Cancer Res 20:2182-91
|Beattie, Bradley J; Pentlow, Keith S; O'Donoghue, Joseph et al. (2014) A recommendation for revised dose calibrator measurement procedures for 89Zr and 124I. PLoS One 9:e106868
|Lee, Ming-Ching; Buitrago, Daniel H; Kadota, Kyuichi et al. (2014) Recent advances and clinical implications of the micropapillary histological subtype in lung adenocarcinomas. Lung Cancer Manag 3:245-253
Showing the most recent 10 out of 119 publications


text: Amanda Seyfriend & You Have The Same Christmas TraditionDodai Stewart3/08/11 8:31pmFiled to: notable quotableamanda seyfriedCelebrityElle MagazineRomcom35EditPromoteShare to KinjaToggle Conversation toolsGo to permalink On romcoms: "I don't think I'm being very 'artistic' when I do them, but I'm not doing it for that reason. Romantic comedies make me happy. I watch Love Actually every Christmas."Reply35 repliesLeave a reply


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Bonita is a short haired black and white female born approx 2007. A lovely big and healthy cat who is friendly and gentle with other cats and people. She has very quirky markings on her face.
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Watch It Was a Wonderful Life
This documentary takes a journey alongside a woman down on her luck. Once living amongst middle class Americans, she now lives homeless due to a series of misfortunes that began with a bitter divorce. Now, she struggles each day and not sure what is next in life.
| 1993 | 1 hr 24 min | 10 /
- Cast
- Jodie Foster, Lou Hall, Reena Sands, Josephine, Marie
- Studio
- Jane Balfour Films Limited
- Director
- Michele Ohayon
- Language
- English