text:
Where a watercraft insurance policy excludes bodily injury coverage for any insured, defined as a person "legally responsible" for the boat, a trier of fact must determine whether injured party was an insured. "Carl and Laurie Bowers own a 2003 ...Read More »
Premises Liability – Licensee not entitled to warning about motor oil in parking lot
Where plaintiff slipped and fell on motor oil in defendant church's parking lot, the trial court correctly concluded that plaintiff was a licensee on the premises. The case was properly dismissed because the church did not breach any duties owed ...Read More »
Medical Malpractice – Plaintiff's case dismissed after expert deemed unreliable
The trial court correctly directed a verdict for defendants after determining that plaintiff's only expert witness could not provide reliable testimony. "This case is a medical malpractice action brought by plaintiff after the death of Therel Kuzma, who died from ...Read More »
Civil Rights – Murder of plaintiff's decedent not caused by state-created danger
Plaintiff cannot amend her complaint to name the director of the Michigan Department of Corrections who, plaintiff alleges, is liable for her aunt's death because officers who answered to him poorly supervised the parolees who murdered her. Plaintiff has not ...Read More »
Insurance – Estate collaterally estopped from litigating causation
A marine insurer is not liable for coverage of a drowning-death claim against its insured because the issue of causation was resolved against the decedent's estate in related litigation. Carleton had marine insurance through New Hampshire Insurance Co. Carleton and ...Read More »
No-Fault – Pre-existing medical conditions doom serious impairment claim
A no-fault insurer is entitled to summary judgment of plaintiff's claim that she suffered a serious impairment of body function because the claimed injuries did not interfere with her general ability to lead a normal life. "The evidence submitted to ...Read More »
Workers' Compensation – Conflict certified concerning workers' comp employee test
Under MCL 418.161(1), as interpreted by Amerisure Ins Co v Time Auto Transp, Inc, 196 Mich App 569; 493 NW2d 482 (1992), the injured party was an independent contractor, and thus, plaintiff insurer owes no coverage under a workers' compensation ...Read More »
No-Fault – Broad release bars claim for modified van
The trial court erred by reinstating plaintiff's case after she settled with her no-fault insurer because the parties' release encompassed, in unambiguous terms, all of her claims, including her unfulfilled claim for a modified van. Plaintiff lost her leg in ...Read More »
Governmental Immunity – Sufficient notice of defect in sidewalk-injury claim
The trial court correctly ruled that plaintiff provided defendant city with sufficient information concerning the location of her injury on a freeway overpass. "Plaintiff's notice described the location of the incident in two ways. First, the notice referenced the location ...Read More »
Governmental Immunity – Sidewalk-injury plaintiff gets to jury on constructive notice issue
In this sidewalk-injury claim brought under the highway exception to governmental immunity, the trial court correctly denied defendant summary disposition because there was a material dispute whether the city had constructive notice of the defect. The court properly considered an ...Read More »


text:
* required fields
What is the Carbon Footprint of Your Escalator?
An escalator powered by a 20HP motor operating 24 hours a day, 7 days a week, will use about 28,000 kWh per year. According to the U.S. Environmental Protection Agency's/Department of Energy's ENERGY STAR® program, generating 1 kWh of electricity produces 1.55 pounds of CO2 (the average car produces 11,560 pounds of CO2 per year).
This means that one escalator creates roughly 43,000 pounds of CO2 per year (the equivalent of four cars' worth of CO2 per year). How can you reduce your carbon footprint? Using equipment that can control your escalator's motor efficiency can reduce escalator energy consumption by 30 percent: This means saving 8,400 kWh per year per escalator, which equals 12,900 pounds of CO2. That's equal to one car off the road.
Power Efficiency Corporation
By Christine Toledo
Energy is a major issue today in the United States. We are faced with the challenge of finding new energy solutions through conservation and alternative energy sources. The most effective solution is often through energy-efficiency technologies.
Buildings are one of the largest users of electricity. According to the Washington, D.C.-based Energy Information Administration, buildings account for 79 percent (or $214 billion) of total U.S. electricity expenditures. As of 2003, there were 4,859,000 commercial buildings alone. Most buildings consume a significant amount of electricity through the operation of vertical transportation equipment (elevators, escalators, and moving walks). This equipment generally runs all hours that the building is open for operation.
Several methods for reducing electricity consumption for vertical transportation equipment have been considered, including energy-saving technologies. In general, there are three alternatives to making escalators and moving walks more efficient:
1)Turn the power switch to "off."There's no denying that the best way to save energy is to shut off the equipment. But, if the equipment needs to be running, then it obviously can't be shut off.
2)Install a variable frequency drive.Variable frequency drives (VFDs) can positively impact energy consumption; however, they do not meet current U.S. code for escalator safety, and the additional sensors and equipment that are required to retrofit existing escalators can be expensive.
3)Install equipment that can control efficiency of the motor.This equipment can leave the speed of the escalator unchanged, but can reduce power consumption when few riders are on it. A test by Reno, NV-based Nevada Power, the electric utility for Southern Nevada, on a 40HP escalator motor at a Las Vegas Strip casino showed a reduction in average power consumption of 37 percent (see graph) when using this type of product.
With energy efficiency and the curbing of greenhouse-gas emissions ranking among the highest national priorities, solutions for vertical transportation efficiency will continue to contribute to the overall effort to reduce power consumption.
Christine Toledo (email@example.com) is marketing communications manager at Las Vegas-based Power Efficiency Corp. (http://www.powerefficiencycorp.com/).
Polyglass U.S.A., Inc. has been manufacturing premium roofing products in North America for 25 years. Learn about our CURE Technology and ADESO Technology, innovations that have transformed the roofing industry.
Utility Vehicle Alert! Don't Get Framed. Rust can eat right through most UTV frames, destroy your investment and disable your crews. But this simple step stops rust in its tracks.

subset: commoncrawl


text:
Pale Recluse
Archenemy — Common
Creature — Spider
Pale Recluse is legal in the following formats:
French Commander
Modern Duel Commander
Recently viewed cards:
Archenemy — Common
Creature — Spider
Pale Recluse is legal in the following formats:
French Commander
Modern Duel Commander
TCGPlayer avg. price:
Legendary Creature — Angel (4/5)
You and Humans you control have hexproof.
, Exile a card from your graveyard: Put a 1/1 white Human Soldier creature token onto the battlefield.
Creature — Dragon (6/6)
When Arashin Sovereign dies, you may put it on the top or bottom of its owner's library.
Legendary Creature — Elder Dragon (5/7)
Dragonlord Dromoka can't be countered.
Flying, lifelink
Your opponents can't cast spells during your turn.
Legendary Creature — Frog Horror (6/6)
At the beginning of your upkeep, sacrifice The Gitrog Monster unless you sacrifice a land.
You may play an additional land on each of your turns.
Whenever one or more land cards are put into your graveyard from anywhere, draw a card.
Creature — Human Shaman Werewolf (0/0)
Sage of Ancient Lore's power and toughness are each equal to the number of cards in your hand.
When Sage of Ancient Lore enters the battlefield, draw a card.
At the beginning of each upkeep, if no spells were cast last turn, transform Sage of Ancient Lore.
Creature — Treefolk (6/6)
Whenever a creature you control with toughness 4 or greater dies, draw a card.
Creature — Spider (2/5)
Reach (This creature can block creatures with flying.)
Watcher in the Web can block an additional seven creatures each combat.
Legendary Creature — Spider (3/5)
Delirium — When Ishkanah, Grafwidow enters the battlefield, if there are four or more card types among cards in your graveyard, put three 1/2 green Spider creature tokens with reach onto the battlefield.
: Target opponent loses 1 life for each Spider you control.
Creature — Angel (5/5)
Flying (This creature can't be blocked except by creatures with flying or reach.)
When Aegis Angel enters the battlefield, another target permanent gains indestructible for as long as you control Aegis Angel. (Effects that say "destroy" don't destroy it. A creature with indestructible can't be destroyed by damage.)
Creature — Angel (4/4)
Flying (This creature can't be blocked except by creatures with flying or reach.)
Vigilance (Attacking doesn't cause this creature to tap.)
Creature — Hydra (0/0)
Ulvenwald Hydra's power and toughness are each equal to the number of lands you control.
When Ulvenwald Hydra enters the battlefield, you may search your library for a land card, put it onto the battlefield tapped, then shuffle your library.
Creature — Vampire Shaman Ally (4/4)
Cohort — , Tap an untapped Ally you control: You draw a card and you lose 1 life.
Legendary Creature — Demon (6/6)
Whenever a permanent owned by another player is put into a graveyard from the battlefield, you draw a card and you lose 1 life.
Creature — Eldrazi Hippogriff (3/4)
Emerge (You may cast this spell by sacrificing a creature and paying the emerge cost reduced by that creature's converted mana cost.)
When you cast Wretched Gryff, draw a card.
Creature — Eldrazi (4/4)
Devoid (This card has no color.)
Whenever a creature you control deals combat damage to a player, you may draw a card.
: Target creature can't be blocked this turn. ( represents colorless mana.)
Creature — Eldrazi (5/5)
Untap Endbringer during each other player's untap step.
: Endbringer deals 1 damage to target creature or player.
, : Target creature can't attack or block this turn.
, : Draw a card.
Creature — Eldrazi Processor (3/5)
Devoid (This card has no color.)
, Put a card an opponent owns from exile into that player's graveyard: Draw a card, then discard a card.
Creature — Zombie Horror (3/5)
When Lamplighter of Selhoff enters the battlefield, if you control another Zombie, you may draw a card. If you do, discard a card.
Creature — Angel Ally (4/4)
When Angel of Renewal enters the battlefield, you gain 1 life for each creature you control.
Creature — Beast (7/6)
Trample, hexproof
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text:
Отели рядом с Кафедральный собор Палермо
Гостиница в Палермо
This 4-star hotel enjoys a prime location in the heart of Palermo, by Politeama Square. It is housed in a traditional building and provides chic modern accommodation. Especially recommended for its convenient location.
This 4-star modern hotel is situated in the centre of Palermo, just one block from the Palazzo Steri and Piazza Marina. It offers pleasant environment, friendly and courteous staff and comfortable accommodation in a tranquil but central location.
The 3-star Athenaeum hotel offers comfort and convenience in Sicily's historic capital.


text:
battery operated LED lights
Worried about long electricity bills? Install battery operated led lights at your premises to save big on
your bills. You can also use these lights for Halloween costumes or stage. They are also ideal for wedding, birthday party, kiosk or any other event. Being versatile and durable, these lights are very famous amongst the people. We, at Led Montreal, offer a large range of products including LED projectors, LED Strips, party accessories, Rigid LED bars and all other LED gadgets online. We deliver all the products directly in various locations like Canada, Montreal, Quebec and all over the world. As well, we offer all the products at very competitive prices. To change the appearance of your place, you can order these lights from us. Explore our online portal today to buy these energy efficient products at cost-effective prices. You can also call us at our toll free number to place an order.
Print this page
If you are searching top quality and affordable LED awning lights, then you should look none other than LED Montreal.
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Do you want to spice up your home decoration and bring a unique touch on special occasion? If yes, then
If you are seeking Eco-friendly products to minimize your electricity bills, then you must explore our online portal LED Montreal.
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text:
Bill –
You truly
are a stitch. Sounds like your
wife has kept you around for 36 years purely for laughs at your shenanigans.
(NJ / Zone
From: firstname.lastname@example.com
Sent: Wednesday, June 04, 2003
To: firstname.lastname@example.com
Subject: Re: [iris-photos] Free
Adult Personals
In a
message dated 6/4/2003 4:14:54 PM Central Daylight Time, firstname.lastname@example.com
If what
I said ( the four letter word) was "marginal" and what they
"it wasn't all that bad" ----------- Sounds like the wrong person was
to leave------- I was really enjoying the sight but you can unsubscribe
You should not leave. I'm thinkin' you do not have a problem. To explain
further there was all this talk goin' on about bill dookie. Bein' a little
slow, I was kinda' offended cause my wife is always fussin' about the same, us
livin' in a one bathroom house and all, plus me havin' a bent toward
slovenliness about my desk, and the coffee table and the kitchen table, on the
couch, and in the yard, and most everywhere else an iris catalog might be laid
down. She just does not quit. In 36 years she has not quit and I have not
changed much. I figgered yawl were just a pickin' on me at first. About
that same time, I posted a picture of Frosty Jewels which had by some quirk of
fate wound up in the bed with the Gay Geisha. Then I got an off list email
raggin' me bout the Charmin ad attachment to my Frosty Jewels that I did not
understand until I was sent to the Mallorn archives to see what had posted.
On top of all that, I now fear my wife may well see that ad in the archives and
find another husband to support if the notion gets put in her head.
And you think you got trouble.
That famous Southerner, Winston Churchill, said never, never, never give up.
Kindly reconsider. Some, for sure one, appreciate succinct words that express
ones thoughts precisely. It would have been impossible for you to say as much
with fewer words using that other Southerner's English.
Bill Burleson 7a/b
Your use of
Yahoo! Groups is subject to the Yahoo!
Terms of Service.


text:
We'll respond shortly.
At Pivotal Labs, one of the services we provide our clients is helping them interview and hire. Pivotal Labs and our clients place a strong emphasis on Agile development and its many aspects: Pair Programming, Test-Driven Development, rapid iterations, and frequent refactoring.
Below is the description for a Ruby developer position for Post+Beam, who connect with audiences by listening to their needs, and influencers by understanding their vision. The result is innovation: new products, experiences and processes. Our expertise in communication gets the word out.
Post+Beam is hiring senior Ruby on Rails developers – here's why you want to work there:
You will be building web applications and designing websites for clients across multiple industries that integrate with various platforms and third party APIs. This requires rock solid RoR development skills and the ability to work fluidly with a design team.
You will be working for an incubator of funded startups, backed by years of agency experience in PR, marketing, design, and development. This is a fast-paced position that focuses on mobile and web development in multiple industries. As such, your will role will have a heavy stake in product development.
You will be expected to participate in all phases of our software development life cycle to convert concepts and specifications into released web applications and websites. You will be the lead developer at our SF office and work collaboratively with our other offices and realize this is not a managerial position.
Our offices are in beautiful South Park in San Francisco. We are very interested in people looking to relocate to join our team.
We pay special attention to those that are looking to create the new, not just re-purpose the old. Special consideration will be given to those that show entrepreneurial spirit, are looking to mold the organization, and help create a better agile development environment.
Candidates should have solid communication skills: on one hand they should be able to "speak truth to power" but at the same time be able to listen to and understand strategic business, design and user needs.
Based on experience, talent and ability to innovate and communicate. Strong bonus tied to delivery of successful startups in the incubator.


text:
Write ups and small product reviews
This project received 6 bids from talented freelancers with an average bid price of $7 USD / hour.Get free quotes for a project like this
Project Budget$2 - $8 USD / hour
Total Bids6
Project Description
We are looking for writers for our Auto insurance website. You will need to create short (20-30 word) write ups and small product reviews. We will pay $[url removed, login to view] to start up, then increase if it goes well. You need to be interested in insurance to take up the job.
Due to payment issues, we can only take writes that are based in the USA for now. Please send an email to to apply if you fit the criteria.
Thank you,
A Shankland
Skills Required
Looking to make some money?
- Set your budget and the timeframe
- Outline your proposal
- Get paid for your work
Hire Freelancers who also bid on this project
Looking for work?
Work on projects like this and make money from home!Sign Up Now
- Forbes
- The New York Times
- Time
- Wall Street Journal
- Times Online


text:
from Mexico
December, 2013
Raúl is a great host! Very nice Studio :)
Affordable, clean, fully furnished Miami Studio in Historic Little Havana with WIFI. 5-10 minutes from South Beach, Coral Gables, Coconut Grove, & Miami International Airport.
Only one and a ½ blocks from World Famous Calle Ocho, in the center of Miami's Historic Cuban District, this studio is just a few steps away from cafes, shops, restaurants, museums, Cuban cigar boutiques, and art galleries, and a 5 minute walk from the Domino Park, The Tower Thearter, Cubaocho, and the Lasa de Tula.
Situated in the absolute heart of Miami between Calle Ocho and 5th at 15 avenue, this studio features new furnishings, flat screen TV, gated and secured parking for one vehicle, yard, and sleeping accommodations for a maximum of one to two.
* Flat screen TV
* Cable with PPV
* Air conditioning
* One and a ½ blocks from Calle Ocho
* Completely furnished... New linens, towels, everything...
* One queen-size bed
* Desk
* Full bath
* Towels, and iron are included.
from Mexico
December, 2013
Raúl is a great host! Very nice Studio :)
from Mexico
December, 2013
Raúl is a great host! Very nice Studio :)
from United States
September, 2012
It was a really nice holiday. Everything was OK.
Other reviews for Dvitalio
from Brazil
December, 2014
from India
February, 2014
No complaints Best stay here
For the best experience, update your browser to view this website correctly. Update my browser now


text:
Delores L. Krueger wrote:
> Dee Krueger-Rosendale, Wi
> I got my hosta rom on Monday, but I don't know how to open it. Would
> appreciate any help. Thanks, Dee
Hi Dee
If you open the cd in some program and look at all the file extensions
I might be able to help.
Bob Axmear 208 2nd St Ne Waukon,Ia 52172-1308 319 568-4859
http://www.hostasonline.com/ Hostasonline.com
http://www.hostasonline.com/webwork.html WEBWORK
To sign-off this list, send email to firstname.lastname@example.com with the
message text UNSUBSCRIBE HOSTA-OPEN


text:
If you are living in Detroit, Michigan and want to sell your scrap at great price, then contact Basic Metal, The [Scrap Metal Recycling Company][1] located in Detroit. Its a full service industrial recycling company. Basic Metals operate 2 big junk scrap yards which is best for production scrap, commercial cleanouts, automotive scrap, junk cars and also for the public as well. Sell your scrap Now !
Our website : http://basic-metals.com/
Call Us For A Free Consultation : 1-586-465-8000
[1]: http://basic-metals.com/
Ad ID: 19606


text:
Too Young for the Army? Israeli Soldier Deserts, Develops Anorexia
One of the many challenges that faces the Israel Defense Forces is the fact that its conscripts are essentially kids. A few weeks before getting their uniforms they are sitting in classrooms and being told by their moms not to stay out too late. The army finds itself in loco parentis.
A heartbreaking example of how this arrangement can go wrong is revealed in today's Israeli press. According to reports, a young female conscript felt that she'd been abused by her commander. She then deserted and developed eating patterns associated with anorexia. Her father realized that because she's a soldier, her only source of medical care would be through the army — and so he turned to the military police. Unfortunately, the police didn't take the call as a cry for help, but rather as an aid in the search for a wanted person. The former soldier was arrested and imprisoned her for two weeks, which are up today.
According to Ynet, "Her parents were appalled to discover her painfully emaciated when they arrived for a hearing at the Jaffa Military Court." The same article quotes her father saying: "She was so thin that sitting on the bench actually hurt her. She had to wear sweat pants underneath her uniform."
Your Comments
The Forward welcomes reader comments in order to promote thoughtful discussion on issues of importance to the Jewish community. In the interest of maintaining a civil forum, The Forward requires that all commenters be appropriately respectful toward our writers, other commenters and the subjects of the articles. Vigorous debate and reasoned critique are welcome; name-calling and personal invective are not and will be deleted. Egregious commenters will be banned from commenting. While we generally do not seek to edit or actively moderate comments, our spam filter prevents most links and certain key words from being posted and the Forward reserves the right to remove comments for any reason.


text:
Wit & Wisdom
Aztec Print Ankle Jeans (Nordstrom Exclusive)
Product not available
Have questions?
Chat with us or call 1.888.282.6060.
HideDetails & Care
Fading at the thighs and seat adds dimension to the blue-tone print of slim jeans in soft, stretch denim. Signature details include an angled coin pocket and extra inset pocket in back.
- Approx. inseam: 26 1/2" with 13" leg opening.
- Approx. rise: front 9 1/2"; back 14".
- Measurements taken from size 8 and may vary slightly by size.
- Zip fly with button closure.
- Six-pocket style.
- Cotton/polyester/spandex; machine wash.
- By Wit & Wisdom; imported.
- Point of View.


text:
Free personalized radio that
plays the music you love
Release Yourself
Features of This TrackR'n'B influences
electronic music influences
smooth jazz influences
group vocals
brass section
synth drums
vibes playing
synth playing
synthetic bass part
electric guitar accompaniment
interesting part writing
strong melodies
a groove oriented approach
lyric-centric composition
use of rhythmic loops
insistent backbeats
mixed major and minor tonalities
and many other similarities identified in the Music Genome Project
These are just a few of the hundreds of attributes cataloged for this track by the Music Genome Project.show more
Similar Tracks
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text:
BlackNews.com – 2.4 Million Businesses in United States Owned By Women of Color
Nationwide – Women everywhere are starting businesses, and are increasingly successful at it. As of 2002, there were nearly 7 million women-owned businesses in the country. According to the U.S. Census, 2.4 million (34%) of those are owned by women of color (African Americans, Hispanics, Asians, and Native Americans).This large group of minority business women are not just running traditional businesses like restaurants and hair salons. Many are running professional companies that offer a variety of services including: advertising, public relations, accounting, staffing, government contracting and more.
According to the National Association of Business Women and Moms (NABWM), women have also become incredibly active in the field of network marketing.
Companies such as Mary Kay, Herbalife, Color Me Beautiful, Warm Spirit, and Isagenix have recruited a record amount of business women who now work as consultants and sales associates. It's currently unknown, however, as to whether or not network marketing women are considered to be actual businesses owners.


text:
OpenBus means increased safety. We call it "First Failure Safe". To put it simple, this means that you don't see unintended movement in your application because of short circuited wires. Because with OpenBus the signal is being transferred by Bits and Bytes. No connection means no signal. This means extra safety as opposed to analogue systems where you don't get this feature. On top of this we have a separate wire in the cable which must be enabled before movement is possible. Called "Power Request". No request for power means no movement!
Advanced applications might have a need for clever movement. With the microprocessor you can configure your system to operate in certain predefined patterns. You can configure it to stop at a specific time when moving, or make it operate simultaneously or in parallel in the way you want it to.
OpenBus offers a lot of flexibility in order to address the differentiated needs in the market. Customer needs tend to vary and OpenBus can meet your specific requirement for a customized solution. The software can be made to realize the exact movement, set-up and optional features you want to see in the future application.
LINAK offers flexibility by combining the products to fit your specific need. Please contact your LINAK partner for designing the right system according to your application.
An advantage with OpenBus is that you get more flexibility when creating your system solution. Our OpenBus-compatible products comes with "mini-fit" cable-plug. This means you can interchange all the OpenBus control boxes with all of our common actuators and attendant controls, so your logistical flow will be optimized.


text:
Follow Us!
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5 Reasons to Own a Hunting Dog
If you already own a hunting dog you know there are a million reasons to do so. If it's a decision you've been debating, we've pooled our TOP 5 REASONS why should go ahead and pull the trigger bring home that pup. Health – Ever heard the expression "if your dog's out of shape, you're Read the Rest…
How In-Ground Fences Help with Hunting Dogs
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Monthly Archives: October 2012
Don't Overlook Steady in Your Wetland Training Arsenal
When you think of wetland hunting with your pup, the importance of water retrieves is probably the first thing that comes to your mind. Steady is also an incredibly important command for a waterfowl dog. As we all know too well, the sport takes patience for yourself and your dog. Make sure you've prepared him Read the Rest…
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Treating Paw Injuries in Hunting Dogs
A couple of weeks ago, we discussed the preventative measures to take to ensure your dog's paws stay healthy in the field. Unfortunately, as we all know too well, even when you take all the right precautions, injuries happen. With that in mind, this week we thought we would share a couple of tips for Read the Rest…
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text:
Tea Tree Essential Oil is a 100% pure essential oil made by Aura Cacia. Tea Tree Essential Oil has a warm, spicy aroma.
It can be used alone or blended with Lavender Oil to freshen cloth diapers in the wash. You can also use it to control odors in the diaper pail and even use it in your favorite
cloth wipe solution recipe.
Lavender Essential Oil is naturally cleansing and purifying!
Ingredients: 0.5 oz Melaleuca alternifolia (tea tree) oil
Warnings: Keep out of reach of children. For external use only. Dilute properly; skin irritant.


text:
In the previous funding period we identified immunogenetic loci that an unrelated donor (URD) KIR B haplotype yields statistically significant and meaningful improvement in protection against relapse and relapse free-survival fpr patients with AML. New analyses have refined the favprable KIR B loci to those which encode donor KIR activating receptors associated with improved clinical outcome. We will further explore the clinical importance of these genetic loci by prospectively evaluating the logistics and clinical impact of donor selection by KIR genotyping for URD hematopoietic cell transplantation (HCT) in AML. We hypothesize that amongst URD with optimal HLA matching, donor KIR genotyping can identify better donors likely to yield improved clinical outcome. In conjunction Project 1, we will explore the functional significance of these KIR B loci, their interaction with HLA Class I and allelic polymorphism in the KIR regions to further refine our understanding and methods for prospective donor selection. With Project 2 we will analyze NK cell functional development over time after URD HCT and correlation of this NK development with the complications following HCT including engraftment, GVHD, infections, relapse and survival. These unique analyses accompany a BMT CTN prospective trial testing blood vs. marrow as a graft source for URD HCT and offer a unique platform for understanding how NK cell development, KIR genotyping and functional immune reconstitution can modify post-transplant complications and outcomes. Additionally, the fundamentals of NK cell therapy to reduce recurrence of resistant leukemia and improve sun/ival after transplantation will.be directly tested. In a multicenter trial of reduced intensity haploidentical HCT plus donor NK infusions for resistant AML we will evaluate the direct impact of NK cell therapy on highly resistant leukemia. Prospective clinical trials will define elements essential for safer application of this treatment. Overall, these studies can improve the survival and relapse protection following allogeneic HCT for AML. Our studies outline new and exciting opportunities to improve donor selection and maximize the safety and effectiveness of allotransplantation.
Patients with advanced acute leukemia can be treated with donor transplantation, but improved means to select donors, enhance immune recovery after transplantation and control the risks of relapse have direct application in improving patient survival. These studies will change transplant practice to utilize NK cells to make transplantation safer and more effective.
|Presnell, S R; Al-Attar, A; Cichocki, F et al. (2015) Human natural killer cell microRNA: differential expression of MIR181A1B1 and MIR181A2B2 genes encoding identical mature microRNAs. Genes Immun 16:89-98
|Cichocki, Frank; Schlums, Heinrich; Li, Hongchuan et al. (2014) Transcriptional regulation of Munc13-4 expression in cytotoxic lymphocytes is disrupted by an intronic mutation associated with a primary immunodeficiency. J Exp Med 211:1079-91
|Cooley, Sarah; Weisdorf, Daniel J; Guethlein, Lisbeth A et al. (2014) Donor killer cell Ig-like receptor B haplotypes, recipient HLA-C1, and HLA-C mismatch enhance the clinical benefit of unrelated transplantation for acute myelogenous leukemia. J Immunol 192:4592-600
|Bachanova, Veronika; Miller, Jeffrey S (2014) NK cells in therapy of cancer. Crit Rev Oncog 19:133-41
|Foley, Bree; Felices, Martin; Cichocki, Frank et al. (2014) The biology of NK cells and their receptors affects clinical outcomes after hematopoietic cell transplantation (HCT). Immunol Rev 258:45-63
|Miller, Jeffrey S; Rooney, Cliona M; Curtsinger, Julie et al. (2014) Expansion and homing of adoptively transferred human natural killer cells in immunodeficient mice varies with product preparation and in vivo cytokine administration: implications for clinical therapy. Biol Blood Marrow Transplant 20:1252-7
|Felices, Martin; Lenvik, Todd R; Ankarlo, Dave E M et al. (2014) Functional NK cell repertoires are maintained through IL-2R? and Fas ligand. J Immunol 192:3889-97
|Gleason, Michelle K; Ross, Julie A; Warlick, Erica D et al. (2014) CD16xCD33 bispecific killer cell engager (BiKE) activates NK cells against primary MDS and MDSC CD33+ targets. Blood 123:3016-26
|Sarkar, Chandrima; Cooley, Sarah; Srivastava, Jaideep (2014) Robust Feature Selection Technique using Rank Aggregation. Appl Artif Intell 28:243-257
|Bachanova, Veronika; Cooley, Sarah; Defor, Todd E et al. (2014) Clearance of acute myeloid leukemia by haploidentical natural killer cells is improved using IL-2 diphtheria toxin fusion protein. Blood 123:3855-63
Showing the most recent 10 out of 44 publications


text:
1. In a large bowl, soak the chia seeds in almond milk. You can add as much almond milk according to the preferred consistency of pudding. If you like it thick add less of the milk and if you like it runny, add more.
2. Stir in the frozen goji berries and blueberries along with the juice in the packet. Again you can add more or less as per your liking.
3. The pudding taste good as is but if you like your desserts to be sweeter, add a little stevia. You can also sweeten it with agave or raw honey if you like.
4. Stir in ground cinnamon. You can freshly grate it or use a bottled powdered one.
5. Give a good stir and place the bowl in the refrigerator to chill and set the pudding.
6. When the pudding can thickened and resembles rice pudding, spoon into serving bowls and enjoy cold.
Serving size Per servingComplete recipe
Calories 391 Calories from Fat 163
% Daily Value*
Total Fat 19 g29.8%
Saturated Fat 8.8 g43.8%
Trans Fat 0 g
Cholesterol 0 mg
Sodium 61.2 mg2.5%
Total Carbohydrates 51 g17.2%
Dietary Fiber 12.6 g50.5%
Sugars 28.1 g
Protein 8 g15.6%
Vitamin A 117.2%
Vitamin C 19.6%
Calcium 22%
Iron 7.6%
*Based on a 2000 Calorie diet


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Eye For Film >> Festivals >> Sundance >> 2017 >> Kids
Family viewing.
View other Sundance Film Festival Films by strand: Documentary Premieres, Midnight, NEXT, Premieres, Spotlight, US Documentary Competition, US Dramatic Competition, World Cinema Dramatic Competition, World Documentary Competition
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Moving on up Anna Rose Holmer on adolescence, gender identity and self-determination in The Fits.
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Q: Does a CMVS Board of Trustees (BoT) need to file to become a public/non-profit entity before submitting an application? If so, what type of public/non-profit entity?
A: A CMVS does not become a public entity until the Board of Elementary and Secondary Education (Board) grants a certificate to its proposed board of trustees. Entities completing an application for a CMVS do not need to incorporate as non-profits prior to filing a proposal. A CMVS may not incorporate.
Q: Can single districts be an education collaborative?
A: No. "Two or more school committees of cities, towns, and regional school districts and charter school boards may establish an educational collaborative." 603 CMR 50.03(1).
Q: Can a collaborative newly established by the Greenfield Public Schools (Greenfield) both sponsor and then serve as the CMVS?
A: A collaborative may seek to establish a CMVS but cannot also serve as the CMVS. As a part of its proposal, an entity seeking to establish a CMVS must identify a proposed board of trustees for the CMVS. If a certificate is granted, the Board grants the certificate to the proposed board of trustees, and the board of trustees becomes the public agents authorized to oversee and govern the CMVS. A CMVS operates independently of any school district or collaborative. Greenfield will become a "sending district" for students who reside in Greenfield and enroll in a CMVS fulltime and will pay a tuition to the CMVS for each such student.
If Greenfield were to utilize a collaborative as the entity filing a proposal for a CMVS, that collaborative will not have the advantage provided to Greenfield in Section 6 of Chapter 379 of the Acts of 2012.
Q: Can a collaborative be in non-contiguous cities/towns? Regions?
A: Yes. There is no requirement that a collaborative be made up of contiguous cities, towns, regional school districts, and charter schools.
Q: What provision is ESE prepared to make to accommodate the likelihood that Greenfield, as a first round CMVS applicant, cannot fully meet all governance and employment requirements by the submission date of March 25th?
A: The commonwealth virtual schools law was signed on January 2, 2013, providing very specific language addressing Greenfield. The RFP contains essentially those requirements specified in the statute. The due date for the RFP was established to avoid a gap between the end of MAVA as a Greenfield school and the opening of the new CMVS. As part of its response, Greenfield must submit a proposed board of trustees. Without a proposed board of trustees acceptable to the Commissioner and to the Board, there is no entity to which to grant a certificate for a CMVS.
The proposed board of trustees must be independent of and autonomous from Greenfield. Arguably, there may be some overlap but it cannot be a majority of the membership. The school district cannot control the CMVS, and the board of trustees must be able to make decisions that are in the best interest of the CMVS even if those decisions are not necessarily what Greenfield may desire. If contract(s) run between Greenfield and the CMVS, this autonomy will become even more critical because individuals who serve in roles for both entities may be precluded by state ethics restrictions from participating for either entity in certain matters.
The legislation requires Greenfield to submit information addressing all 39 of the elements required in G.L. c. 71, § 94(b). This is the information that the RFP seeks.
Q: How will ESE count students who enroll less than full time in a CMVS prior to the adoption of regulations? [This question is related to concerns about the "2% of enrolled students must come from Greenfield as the sponsoring district(s)" rule. The requirement for 80% of instruction to be virtual for a student to be counted as a virtual school student has been mooted by the statute's elimination of Virtual Innovation Schools.] Can and will ESE implement a similar rule or a new rule (e.g., an FTE model) for students that enroll less than full time. Would ESE apply the same rule to all students regardless of whether they enroll from within or out of district?
A: Only students enrolled in the CMVS as a full time (FTE) will count towards the 2% local enrollment requirement for Greenfield. A CMVS may offer individual courses for other students, including students enrolled in Greenfield, subject to any agreement reached between the CMVS and those districts. Students taking individual courses at a CMVS, however, are not students enrolled in the CMVS for which the CMVS will receive tuition.
A CMVS may enter into agreements with districts that allow students to take individual courses at the CMVS. Section 94(k) of G.L. c. 71 states that "[i]f a commonwealth virtual school offers online courses to students attending other schools, the commonwealth virtual school shall work with the student's district or school to determine whether the online courses meet the district's or school's standards and requirements and what the commonwealth virtual school will charge the student's district or school for such online courses."
Q: If a CMVS applicant plans to contract with a vendor that provides proprietary materials (e.g., curricula), will the applicant be required to include such materials in their proposal when such submissions are stipulated by the RFP? If yes, can we confirm that the reviewing staff will protect the confidential nature of such materials and that they will not be made public?
A: Yes. As part of the application process, materials including curricula must be provided for evaluation of the application. To the extent permitted by law, the Department will not disclose such information in response to requests for public records.
Q: Statute states (11) "a proposed arrangement or contract with an organization that shall manage or operate the school, including any proposed or agreed upon payments to such organization. " Does this establish any limit on ESE stipulating that a CMVS applicant must provide contract(s) for other than an EMO, such as any contract proposed or entered into with a content provider? [The RFP requires the submission of contracts beyond EMOs.]
A: In response to the RFP, applicants must submit proposed arrangements or contracts with any third party provider. Section 94(b)(10) of G.L. c. 71 requires the submission of "the identity of any third party software or curriculum vendors that the school intends to use. " To the extent that draft contracts are available for such vendors, they should be submitted.
Additionally, G.L. c. 71, § 94(b)(11), requires the submission of proposed arrangements or contracts with organizations that are anticipated to "manage or operate the school, including any proposed or agreed upon payments to such organizations. " This includes any subcontracts for managing or operating the school that may be entered into in connection with the primary contract.
Q: Can a CMVS contract with its own sponsoring district(s)/collaborative or another district for goods or services (including full or part time staff)?
A: Yes. A CMVS may contract with a school district for services. Such contracts necessarily limit membership on the board of trustees of the CMVS of individuals that hold a position with the contracting district. For additional information, see the response to question 5.
Q: How can a CMVS meet its non-discrimination responsibilities and at the same time prioritize enrollment of preferred populations identified by the statute? For example:
Q: Can a CMVS refuse to enroll students whose families claim it would be discriminatory (e.g., for religious reasons) if their child was required to meet certain requirements that apply to all public school students such as taking the MCAS and/or be instructed in certain MA content standards?
A: No. A CMVS may not refuse to enroll a student because of a student's religious affiliation or religious beliefs. Such students, however, must participate in the education required by the public school and must take the MCAS.
Q: What flexibility can be afforded to a CMVS that can only find and contract with a teacher from out-of-state who is capable of providing instruction to a small number of students (e.g., who want to learn Swahili) but who is not licensed to teach in Massachusetts? Can the rules for reciprocity be broadened for a CMVS when a MA licensed educator is not available?
A: Section 94(i) of G.L. c. 71 requires a CMVS to hire teachers who have a Massachusetts educator license. A teacher licensed in another state, however, and has three years of experience under such license, may obtain a Massachusetts Temporary license. A Massachusetts Temporary license is valid for one year of employment. To be eligible for employment beyond one year, a teacher with a temporary license would have to obtain an Initial license by passing the requisite MTEL licensure tests.
Q: If a CMVS contracts for a specialty role like a psychologist who may serve very few students, is the CMVS required to follow the regulations for educator evaluation? If yes, wouldn't this only apply to roles that must be licensed?
A: A CMVS that hires a school psychologist would be required to follow the Educator Evaluation regulations with respect to that individual, regardless of the number of students the individual is serving. A school psychologist is a licensed position, pursuant to 603 CMR 7.04(3). The Educator Evaluation regulations require any person employed in a school district requiring a certificate or license to be evaluated in a manner consistent with the regulations.
Q: Need to confirm whether any courses beyond civics (US History) and physical education are required for graduation by the state?
A: United States history and physical education are required courses in Massachusetts. Additionally, the curriculum offered at a CMVS must be aligned with the Commonwealth's curriculum frameworks, and students must meet the competency determination standard by passing the MCAS in order to receive a high school diploma.
Q: If there is no start-up grant or provision, how does the school start, financially? What money does this new school have to do anything at all, such as pay staff for their work, put ads in the paper for enrollment, etc? There will be personnel and other costs over the summer when there are no students and there is no cache from which to draw funds.
A: The state does not have any funding for transition or startup grants for virtual schools. Similar to charter schools, a CMVS might apply for grants and receive start-up funding from a non-governmental resource either though cash advance or an in-kind contribution. Alternatively, the founding group might provide some startup support to the CMVS.
Q: The RFP seems to be missing a question about the mission of the proposed school.
A: The mission is covered in the Executive Summary (page 13): "Summarize the proposed school's mission, educational program, instructional methodology, services, how this potential school will enhance options for students, make online delivery as good as or better than face-to-face delivery, any specialized student focus, and the founding group's capacity to make the school a success."
Q: The RFP seems to be missing questions about the organization of the school by ages and grade and the estimate of total enrollment.
A: These topics are covered in the Commonwealth of Massachusetts Virtual School Applicant Information Sheet (page 14, question 1) in a simplified manner.
Q: The RFP seems to be missing a question about the timetable for admission.
A: This is intended to be covered in III.A. School Characteristics. It was inadvertently not called out as a separate item...
Q: The RFP seems to be missing a question about whether the virtual school will offer online courses.
A: This is covered in the Commonwealth of Massachusetts Virtual School Applicant Information Sheet (page 15, question 6) in a simplified manner.
Q: The following item in the RFP is confusing: "(39) Describe whether the school will establish personalized learning plans that are standards-based for every student. Describe how the learning plan will be developed for new students and available to receiving districts for students who transfer out of the virtual school." What is meant by "receiving districts"? The statute asks about personalized learning plans but "in conjunction with the school district of residence." Are the personalized learning plans required for every student, or just for special education students?
A: Because virtual schools are web based and can capture significantly more information about a student's progress measured against standards, all Commonwealth of Massachusetts Virtual Schools should be able to develop a "personalized learning plan" for every individual student, not just students on IEPs. If at any time a student chooses to transfer back into a brick and mortar school, there would be a personalized learning plan to better inform the new teachers of where the student is academically. This plan should reduce the amount of transition time so that more time is spent on learning. ESE will be providing more guidance on personalized learning plans in the future.
Q: The RFP's Section C: Student Services supports says that a virtual school "must enroll" students with ELL and special education needs. What does this mean? How could a non-English student participate unless all of the texts and materials were in every language and teachers of other languages were available for online coursework and support? Additionally, there might certain types of disabled children who could not function in this environment.
A: State and federal law prohibit discrimination against a number of classifications, including ELL students and students with special needs. A CMVS must recruit and admit all students in a non-discriminatory manner and may not consider these characteristics during the admission process. Once admitted, a CMVS must offer the services required for such students, either directly or through a vendor. A CMVS may not consider ELL status or a student's disabilities or otherwise prevent such students from enrolling.
Q: The question about evaluation (18) gives the impression a school can improvise teacher evaluation. Aren't all Massachusetts public school required to use the new evaluation system for teachers?
A: (Page 15, 9) The application does ask if the CMVS will use the Massachusetts Model System for Educator Evaluation. A CMVS is required to follow the Educator Evaluation Regulations, but a CMVS is not required to use the Model System. If you need more information on the requirements please contact ESE for a referral to an Education Evaluation expert. Once completed, the CMVS regulations will offer additional guidelines around this.
Q: Question (33) asks for communication mechanisms between the board of trustees, teachers and students. The Board generally doesn't have a direct role communicating with teachers or students because it has to be unbiased in the event of having to serve as an impartial hearing body. Is ESE advocating direct communication between the board and teachers and students?
A: The intent of the question is to address multiple communication channels including, but not limited to, communication between the Board of Trustees and school leaders, between school leaders and teachers, and between teachers and students. The intent was not to require the Board to communicate with a teacher or students inappropriately. The proposal should include all of the communication channels so that reviewers understand who is receiving what information, how frequently, and how is it tracked and shared.
Q: The statute (37) asks "WHETHER the school proposes a mechanism to provide meals to students eligible for free and reduced price lunch" and the RFP question asks "HOW the school plans to provide meals to students eligible for free and reduced price lunch." Wouldn't the cost would of setting up such a food service program be prohibitive? What is actually required of the CMVS?
A: ESE has modified the question to ensure it solicited necessary information and not merely a Yes/No answer. State law requires all public schools to make lunches available. G.L. c. 69, § 1C, and the CMVS statute did not waive this requirement. The Department's Nutrition, Health, and Safety unit is very skilled at providing creative solutions to complex meal delivery issues and can be reached at 781-338-6480 or email@example.com. The requirement is not to deliver a hamburger from Greenfield to Salem; more effective methods exist.


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September 22, 2014
NARAL Pro-Choice America on Michael Boggs Lacking Judiciary Committee Support Needed for Confirmation
Today, the New York Times reported that Sen. Patrick Leahy (D-VT), chairman of the Senate Judiciary Committee, said that Michael Boggs could not muster the votes necessary to win the committee's support and proceed to consideration before the full Senate. He would be the first judicial candidate nominated by President Obama to fail because of Democratic opposition.
Said Ilyse Hogue, president of NARAL Pro-Choice America:
"We echo Sen. Leahy's call for Michael Boggs to withdraw his nomination. As we've said from the moment his nomination became public, Boggs lacks both credibility and a demonstrated commitment to equal justice under the law—qualities necessary for a lifetime appointment to the federal bench.
"As more information about his record on choice, civil rights, and LGBT equality came to light, support for his nomination became a political liability for any senator who hopes to maintain their constituents' support.
"Women understand that judges who respect women, their constitutional rights, and their ability to make their own decisions, are an important line of defense against overzealous politicians who often advance anti-choice laws that defy established protections for women.
"Boggs' record of support for discriminatory and callous measures affecting the lives women, communities of color, and LGBT Americans during his time in the state legislature makes clear that he is unfit to serve as a federal judge. His nomination has faced an unprecedented wave of opposition from the moment of its announcement, and he should withdraw his name from consideration."
Seven in ten Americans support a woman's right to choose. New polling shows that women who support choice will be pivotal in the midterm elections this November, with seventy percent of drop off women voters stating that reproductive rights issues are a motivating factor.
Follow the campaign "Speaking Out Against Michael Boggs" here.


text:
Clinical Chemistry and Laboratory Medicine (CCLM)
Published in Association with the European Federation of Clinical Chemistry and Laboratory Medicine (EFLM)
Editor-in-Chief: Plebani, Mario
Ed. by Gillery, Philippe / Lackner, Karl J. / Lippi, Giuseppe / Melichar, Bohuslav / Payne, Deborah A. / Schlattmann, Peter / Tate, Jillian R.
IMPACT FACTOR increased in 2015: 3.017
Rank 5 out of 30 in category Medical Laboratory Technology in the 2014 Thomson Reuters Journal Citation Report/Science Edition
SCImago Journal Rank (SJR) 2015: 0.873
Source Normalized Impact per Paper (SNIP) 2015: 0.982
Impact per Publication (IPP) 2015: 2.238
- Online
- 1437-4331
Hyperhomocysteinemia and arteriosclerosis: historical perspectives
Citation Information: Clinical Chemical Laboratory Medicine. Volume 43, Issue 10, Pages 980–986, ISSN (Online) 1437-4331, ISSN (Print) 1434-6621, DOI: https://doi.org/10.1515/CCLM.2005.172, September 2005
Publication History
- Published Online:
- 2005-09-30
Early concepts of the origin of arteriosclerosis were introduced in the 19th century by Rokitansky and Virchow, who described mural thrombosis, inflammatory damage to arterial intima, increased intimal permeability to plasma, mucoid degeneration of arterial wall, deposition of plasma lipids in plaques, and fibrosis and calcification of plaques. Experimental production of arteriosclerosis by feeding animal foods to rabbits was attributed to protein intoxication by Ignatowsky in 1908 and to dietary cholesterol by Anitschkow in 1913. Newburgh confirmed the protein hypothesis in 1915–1925 but failed to identify which amino acid produced plaques because methionine (1922) and homocysteine (1932) had not yet been discovered. Cases of homocystinuria from inherited deficiency of cystathionine synthase were found to be associated with thrombosis and vascular disease in 1964. The index case of methionine synthase deficiency (cobalamin C disease) was found by McCully in 1969 to be associated with arteriosclerosis, leading to the homocysteine theory of arteriosclerosis. The theory explains experimental arteriosclerosis by deficiency of vitamin B6 in monkeys, choline deficiency in rats, thyroid deficiency in rats, and methionine deficiency in monkeys. The thrombogenic and atherogenic effects of homocysteine were demonstrated in rabbits, baboons and other species, reproducing the pathological findings found in homocystinuria. Clinical and epidemiological studies in the past two decades have demonstrated that elevated plasma homocysteine is a potent independent risk factor for arteriosclerosis in the general population, supporting the validity of the theory.
Keywords: arteriosclerosis; atherogenesis; homocysteine; homocystinuria; methionine
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