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Tag - Seesmic
Kootol targets Apple, more on patent it doesn't own yet
Unknown software house Kootol on Friday sent notice to many companies claiming that they allegedly violate a messaging patent. It targets a wide swath of the industry that includes Apple, Amazon, Facebook, Foursquare, Microsoft, Nokia, RIM, Twitter, and others all allegedly violate a patent for "Method and System for Communication, Advertising, Searching, Sharing and Dynamically Providing a Journal Feed." Unusually, Kootol doesn't actually have the patent and is instead acting on a Notice of Allowance that lets it act on the patent but still requires that it pay for the patent later.
Seesmic drops BlackBerry app due to lack of demand
Seesmic in a notice said it planned to drop all support for the BlackBerry version of its app. As of June 30, the company would swing its attention to the "most popular" platforms, including not just Android and iOS but even the much younger Windows Phone 7 platform. Company founder Loic Le Meur said on Twitter that there was no fallout with RIM.
TweetUp snaps up Twidroid, popurls in Android push
TweetUp today said it had bought Twidroid, maker of what's touted as the most popular Twitter client for Android. It plans to rebadge the app as Twidroyd, purportedly to avoid conflicts with Lucasfilm over trademarks. The deal would let TweetUp better identify very popular Twitter users for its own search business.
Seesmic launches first iPhone app
After an extended wait, Seesmic has released its first self-named Twitter client for the iPhone and iPod touch. The app supports multiple Twitter accounts, along with Facebook, and updating for several other social networks via Ping.fm. Users can create, browse and save Twitter lists, searches and topics, and attach geotagging data to individual tweets.
Twitter plans official Android app
Twitter as part of its first Chirp conference today said it would have an official Android app. When asked about the platform, chief Evan Williams was clear the company would take the same approach used for the BlackBerry and iPhone, where a Twitter-branded download would compete against third-party rivals. He stopped short of explaining whether this would involve buying another company or developing a new app entirely.
Windows Phone 7 development, marketplace detailed
Microsoft at its MIX10 developer event detailed some of how app development and sales will work for Windows Phone 7. Confirming that it's based on Silverlight and XNA, the mobile OS will fence off third-party apps from true native code but will give them access to all the key features: it will recognize accelerometers, cameras and multi-touch gestures. WP7 will also mirror iPhone development by using background push notification for those not allowed to multitask and include a general location service that any app can use.
Twitter turns on geolocation feature
Twitter today added its promised geolocation feature for tweets. The addition gives any app using the API, but not the Twitter site itself, the option of tagging posts with a location as well as to automatically draw on the location for position-based features, such as finding tweets in a certain area. It isn't exclusive to GPS-equipped devices and will work with Wi-Fi and other methods that can generate the relevant data.
Now AAPL Stock: 135.72 ( + 0.38 )
Cirrus creates Lightning-headphone dev kit
Apple supplier Cirrus Logic has introduced a MFi-compliant new development kit for companies interested in using Cirrus' chips to create Lightning-based headphones, which -- regardless of whether rumors about Apple dropping the analog headphone jack in its iPhone this fall -- can offer advantages to music-loving iOS device users. The kit mentions some of the advantages of an all-digital headset or headphone connector, including higher-bitrate support, a more customizable experience, and support for power and data transfer into headphone hardware. Several companies already make Lightning headphones, and Apple has supported the concept since June 2014. http://bit.ly/29giiZj
Apple Store app offers Procreate Pocket
The Apple Store app for iPhone, which periodically rewards users with free app gifts, is now offering the iPhone "Pocket" version of drawing app Procreate for those who have the free Apple Store app until July 28. Users who have redeemed the offer by navigating to the "Stores" tab of the app and swiping past the "iPhone Upgrade Program" banner to the "Procreate" banner have noted that only the limited Pocket (iPhone) version of the app is available free, even if the Apple Store app is installed and the offer redeemed on an iPad. The Pocket version currently sells for $3 on the iOS App Store. [32.4MB]
Porsche adds CarPlay to 2017 Panamera
Porsche has added a fifth model of vehicle to its CarPlay-supported lineup, announcing that the 2017 Panamera -- which will arrive in the US in January -- will include Apple's infotainment technology, and be seen on a giant 12.3-inch touchscreen as part of an all-new Porsche Communication Management system. The luxury sedan starts at $99,900 for the 4S model, and scales up to the Panamera Turbo, which sells for $146,900. Other vehicles that currently support CarPlay include the 2016 911 and the 2017 models of Macan, 718 Boxster, and 718 Cayman. The company did not mention support for Google's corresponding Android Auto in its announcement. http://bit.ly/295ZQ94
Apple employees testing wheelchair features
New features included in the forthcoming watchOS 3 are being tested by Apple retail store employees, including a new activity-tracking feature that has been designed with wheelchair users in mind. The move is slightly unusual in that, while retail employees have previously been used to test pre-release versions of OS X and iOS, this marks the first time they've been included in the otherwise developer-only watchOS betas. The company is said to have gone to great lengths to modify the activity tracker for wheelchair users, including changing the "time to stand" notification to "time to roll" and including two wheelchair-centric workout apps. http://bit.ly/2955JDa
SanDisk reveals two 256GB microSDXC cards
SanDisk has introduced two 256GB microSDXC cards. Arriving in August for $150, the Ultra microSDXC UHS-I Premium Edition card offers transfer speeds of up to 95MB/s for reading data. The Extreme microSDXC UHS-I card can read at a fast 100MB/s and write at up to 90MB/s, and will be shipping sometime in the fourth quarter for $200. http://bit.ly/294Q1If
Apple's third-quarter results due July 26
Apple has advised it will be issuing its third-quarter results on July 26, with a conference call to answer investor and analyst queries about the earnings set to take place later that day. The stream of the call will go live at 2pm PT (5pm ET) via Apple's investor site, with the results themselves expected to be released roughly 30 minutes before the call commences. Apple's guidance for the quarter put revenue at between $41 billion and $43 billion. http://apple.co/1oi1Pbm
Twitter stickers slowly roll out to users
Twitter has introduced "stickers," allowing users to add extra graphical elements to their photos before uploading them to the micro-blogging service. A library of hundreds of accessories, props, and emoji will be available to use as stickers, which can be resized, rotated, and placed anywhere on the photograph. Images with stickers will also become searchable with viewers able to select a sticker to see how others use the same graphic in their own posts. Twitter advises stickers will be rolling out to users over the next few weeks, and will work on both the mobile apps and through the browser. http://bit.ly/29bbwUE


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60 minutes
Bridezillas is a reality series that follows high-maintenance brides-to-be as they suffer the stress of planning, organizing, shopping for, and completing the last minute details of their weddings.
Reality TV Buzz
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Previous Episodes
0 reviews
s10e22 Willaura & Megan
October 11, 2013
One cocky bride-to-be makes some questionable choices after she explodes at her helpers. Also: A wannabe socialite's wedding day turns out to be a disaster.
Series Finale
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s10e21 Adrianne & Willaura
October 4, 2013
One bride-to-be cries a lot, while an Atlanta woman prepares for her "celebrity" wedding.
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kim-berly added it to Reality: Stupid Mind-numbing Civilization Ending
46 shows
Renee Mosley added it to Crazy
1 show
7 show lists

subset: commoncrawl


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Search Results: 'Alumni'
The Alumni
eBook (PDF): $2.73
Three high school classmates graduate into the real world of pro football, the courtroom, and corporate/financial bailouts. They reunite over a case of corporate intrigue and a football injury that... More > lands one in a hospital bed. They end up sharing new wealth and restoring lost relationships with their families.< Less
Anything But Ordinary
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The first two books (When...not if and Fill the Bathtub!), in this series of three, told stories of conflict in the Middle East as experienced by alumni of the American Community School in Beirut. In... More > this volume three distinct "generations" of ACS'ers write about what they perceived as quieter, more peaceful times.< Less
Out of this World: A Coloring & Activity Book
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52 pages featuring 40 Threadless alumni cosmic coloring fun!
Adventure: A Coloring & Activity Book
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An exciting Coloring & Activity book featuring 42 artists from the Threadless Alumni.
Friends of Joni Cookbook
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Recipes from the Literacy Alumni, lovingly picked in honour of Joni's retirement.
Ode to a Scholar (Hardcover)
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This compilation book is a gift to the Meyerhoff Scholarship Program at UMBC, given by Meyerhoff Program Alumni.
Ode to a Scholar (Paperback)
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This compilation book is a gift to the Meyerhoff Scholarship Program at UMBC, given by Meyerhoff Program Alumni.
Marietta High School Memories
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Memories book of Marietta High School (1928-1961), Bellwood, Nebraska. Published by Marietta Alumni. (Coil-bound / lay-flat)
When ... not if
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This book is the first volume of a compilation of stories from conflicts in the Middle East written by alumni of the American Community School at Beirut. The idea came out of a discussion on a... More > mailing list of ACS alumni. Most ACS alumni were teenagers or grade school pupils at the time of their stories, others were faculty or staff. These stories describe their experiences in the Middle East, when they were at ACS, or the dramas of later years. Being at ACS left no one untouched. Some were there only a short period of time, never to return. A few have come back in later years and some just never left.< Less
Fill the bathtub!
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This book is the second volume of a compilation of stories from conflicts in the Middle East written by alumni and faculty of the American Community School at Beirut. Stories from WWI, WWII, 1958,... More > the Six Day War, the '73 war, the Lebanese Civil War, the Gulf War and more - by Maria Bashshur Abunnasr ('84), Bill Allen ('64), Esther Allen (Fac '73 -'75), Catherine Bashshur et.al., T. Robert Bassett (Faculty 52-'56), El. Huntington Bliss ('21), Scott Brunger ('64), Ivy Cleo (Gorkiewicz) Compton-Bishop ('35), Harry G. Dorman Jr. ('22), James Downing ('68), Carol Haeussner ('59), George Herrmann ('63), Julie Johns ('71), Phyllis Glessner Leach ('48), Patricia Falconer Roland ('75), Jim Mandaville ('53), Sherry Brown Schmidt ('58), Susan Meade Sindelar ('69), Ivar Walde ('64), Allen West ('48), Jeanne Comings Majdalany (Fac 44-47).< Less
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Recognizing and...
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Reignite Your Marriage...
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The Genealogist's Google...
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Yhugm: The Last Survivor...
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Dropping Our Nets:...
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Faith Flows Down
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Kingdom Prayer Season
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Having Fun with PBIS:...
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BBVA, Mapre Lead Spain Sell-Off on Emerging MarketsCharles Penty
Spanish banks including Banco Bilbao Vizcaya Argentaria SA, the country's second-biggest lender, and insurer Mapfre SA led declines on Madrid's IBEX 35 Index on concern that a slide in currencies in emerging markets from Argentina to Turkey may hurt earnings.
BBVA, which is largest shareholder in Turkiye Garanti Bankasi AS, Turkey's biggest listed lender, and owns a bank in Argentina, fell as much as 6 percent to 8.77 euros, the steepest decline in 10 months. Mapfre, which does business across Latin America and in Turkey, dropped 3.7 percent. Banco Santander SA, the biggest Spanish bank and which earns about a quarter of profit from Brazil, fell 1.7 percent to 6.46 euros. The IBEX 35 slid 2.2 percent.
"There is going to be a lot of focus on Argentina and Turkey where the potential risks seem highest," Benjie Creelan-Sandford, an analyst at Macquarie Bank Ltd. in London, said in a phone interview today. "The general economic situation has been worsening in Brazil and that's a special concern for Santander if there is more contagion there from Argentina."
Spanish financial firms and companies from Telefonica SA, the biggest phone company, and security services firm Prosegur Cia de Seguridad SA, have relied on emerging markets to shield their earnings against an economic slump in Spain. The Federal Reserve's tapering of monetary stimulus, compounded by growing political and financial instability, has triggered the biggest sell-off in emerging-market currencies in five years.
The Argentine peso is the worst-performing currency in the world against the euro this year, with losses of about 17 percent, while the Turkish lira is the second-worst after falling 7.1 percent.
Prosegur, which gets 12 percent of revenue from Argentina, according to data compiled by Bloomberg based on 2012 earnings, fell 7.6 percent, the biggest drop in a year. Telefonica, which relies on Latin America for about half its revenue, fell 4.6 percent.


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Autoimmune diseases, such as multiple sclerosis, rheumatoid arthritis, diabetes and lupus, etc., affect approximately 50 million Americans. The immune responses of self-reactive T lymphocytes play critical roles in autoimmune diseases. Therefore, identification of novel molecules that regulate T cell immune functions are important for a better understanding of the mechanisms underlying the disease development and for seeking novel therapies. During the current finding period, we have discovered that the type III histone deacetylase Sirt1 as a critical suppressor to T cell immunity and macrophage activation by suppressing the transcription factors AP-1, indicating Sirt1 as a potential therapeutic target for autoimmune and inflammatory diseases. In fact, we further demonstrated that the Sirt1 activator resveratrol prevents/treats type 1 diabetes in mice. Our preliminary study of the current competitive renewal application demonstrates that the deacetylase Sirt1 and the acetyltransferase GCN5 oppositely regulate T cell activation. Genetic deletion of GCN5 gene inhibits T cell immune responses in mice, identifying GCN5 as a critical positive regulator for T cell immunity. Interestingly, treatment of mice with GCN5 specific inhibitor attenuated autoimmune disease development. Therefore, based on the above preliminary findings, we propose that the histone deacetylase Sirt1 is a negative regulator and the acetyltransferase GCN5 is a positive regulator for T cell immunity, and that the Sirt1 activator and GCN5 inhibitor have great therapeutic potentials in treatment of autoimmune diseases. This project is to address this hypothesis using the state-of-art approaches of both immunological and molecular studies. Results from this proposed study discover novel molecular mechanisms behind Sirt1 and GCN5 in T cell activation and autoimmunity, providing rationales for the uses of Sirt1 deacetylase activators and GCN5 acetyltransferase inhibitors in treating/preventing autoimmune diseases.
This study identifies the histone deacetylase Sirt1 as a negative regulator and the acetyltransferase GCN5 as a positive regulator for T cell immune response. Therefore, Sirt1 activators and GCN5 inhibitors have great therapeutic potentials in the treatment of autoimmune diseases.
|Kong, Sinyi; Thiruppathi, Muthusamy; Qiu, Quan et al. (2014) DBC1 is a suppressor of B cell activation by negatively regulating alternative NF-?B transcriptional activity. J Immunol 193:5515-24
|Yang, Heeyoung; Qiu, Quan; Gao, Beixue et al. (2014) Hrd1-mediated BLIMP-1 ubiquitination promotes dendritic cell MHCII expression for CD4 T cell priming during inflammation. J Exp Med 211:2467-79
|Kong, Sinyi; Yeung, Pricilla; Fang, Deyu (2013) The class III histone deacetylase sirtuin 1 in immune suppression and its therapeutic potential in rheumatoid arthritis. J Genet Genomics 40:347-54
|Chen, Weimin; Wang, Huihui; Tao, Shasha et al. (2013) Tumor protein translationally controlled 1 is a p53 target gene that promotes cell survival. Cell Cycle 12:2321-8
|Zou, Ting; Yang, Yi; Xia, Fei et al. (2013) Resveratrol Inhibits CD4+ T cell activation by enhancing the expression and activity of Sirt1. PLoS One 8:e75139
|Lei, Fengyang; Song, Jianyong; Haque, Rizwanul et al. (2013) Regulation of A1 by OX40 contributes to CD8(+) T cell survival and anti-tumor activity. PLoS One 8:e70635
|Kemp, Kyeorda L; Lin, Zhenghong; Zhao, Fang et al. (2013) The serine-threonine kinase inositol-requiring enzyme 1* (IRE1*) promotes IL-4 production in T helper cells. J Biol Chem 288:33272-82
|Qiu, Quan; Zheng, Ze; Chang, Lin et al. (2013) Toll-like receptor-mediated IRE1* activation as a therapeutic target for inflammatory arthritis. EMBO J 32:2477-90
|Lin, Zhenghong; Fang, Deyu (2013) The Roles of SIRT1 in Cancer. Genes Cancer 4:97-104
|Chen, Weiming; Wang, Huihui; Tao, Shasha et al. (2013) Tumor protein translationally controlled 1 is a p53 target gene that promotes cell survival. Cell Cycle 12:
Showing the most recent 10 out of 18 publications


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What do you dislike about your truck?
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Dodge Ram Forum Senior Member
Join Date: May 2010
Location: Walbridge,Ohio
Age: 45
Posts: 275
Gender: Male
Vehicle: 2010 Dodge Ram
Trim Level: SLT QD CAB Big Horn
Color: Brilliant Black Crystal Pearl Coat
Engine: 2009-20?? 345ci (5.7L) Hemi V8 390hp 407lb/ft
Rep Power:
I have had my RAM since May 10, 2010. I have 19,700 mile on it. The transmission (knock on wood) has not had any issues. The passenger seat belt rattle bugs me some. The plastic driver seat rail guard at the bottom left corner, every time it seems like it, when I get in, I hit it with my foot and knocks it loose, or off. The shift knob on the column seems to be to close to cup holders in center. If I am not careful I hit the shifter, afraid I might knock it out of gear. Well, even if I can not, it feels as if I could,lol. The driver side sun visor, leaves a gap between the left side of visor and pillar. That lets sun light hit me in the dang eyes,lol. Most all that i see on here are small design flaws that can be addressed later on in new models. The tune up is not something I am looking forward to, but what can you do. The RAM, I love it. I am glad I bought it, I would do it again. For now I will live with the small stuff and enjoy the rest.
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