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Ashley Olien Travis tweets
Why is Travis Porter 3 people and The Weeknd is 1 person?
3 years ago
Did try to ask Moyes about Ashley Young's form. One of the MUFC press officers jumped in and hurriedly ended press conference
3 years ago
Me and my bro @zach_dorsey lol ashley_anderson dressed as him for celebrity day at school http://t.co/1g5GR9go2l
3 years ago
http://t.co/bBRs9OlSKG - United Keok di Etihad, Ashley Young Banjir Hujatan
3 years ago
Ashley Young: Of every player to attempt 10+ crosses in the PL this season, Ashley Young has the worst cross accuracy (4.5%)
3 years ago
Join us in congratulating Brian and Ashley McCann on the birth of their daughter, Colbie!
3 years ago
"Te doy mi palabra. Ni siquiera pensaré en tus bragas... A menos que quieras que lo haga". —Travis Maddox. http://t.co/sKKpVjeOuB
3 years ago
Sites related to Ashley Olien Travis
Home of bondage star, Ashley Renee, featuring strict sexual bondage, sm and orgasms! High Quality...
Delicious Recipes and Food Photography by Ashley Rodriguez.
3A is a toy, publishing and entertainment company founded in 2008 by Kim Fung Wong and Ashley Wood...
Illustrations and Graphic Design by Ashley Tate


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Welcome to The Phantom Phlashers!
Website updated February 9, 2017
Welcome to the homepage of IPMS Birmingham, the Phantom Phlashers. We are a scale modeling club dedicated mostly to airplanes, but we welcome wholeheartedly (and have a large membership of) scale modelers who are interested in other subjects as well. Kick the tires, light the fires, and enjoy our online modeling resource!
Our next meeting is February 11, 2017. See the meetings page for more information about our meetings.

subset: commoncrawl


text:
- Home
- Protection
- Training
- Shoes
- Apparel
- Uniforms & Gi
- Accessory
Ideal 78cm length allows full 360 degree access around bag when working out. Can be mounted masonry wall. Extra sturdy and strong. Holds bags up to 80kg. Super sturdy, strong and easy to install.
|Wall hanger height
|75,5 cm
|Lenght of the arm
|78 cm


text:
Top Definition
"Wow, my girlfriend tried to cut me last night! I had to break up with that bitch before she tried to kill me.
"DSYDIC, bro!"
"DSYDIC, bro!"
by The Guru Turtle October 16, 2011
The Urban Dictionary Mug
One side has the word, one side has the definition. Microwave and dishwasher safe. Lotsa space for your liquids.Buy the mug
The Urban Dictionary T-Shirt
Smooth, soft, slim fit American Apparel shirt. Custom printed. 100% fine jersey cotton, except for heather grey (90% cotton).Buy the t-shirt


text:
TYLER (KYTX) - February is heart month. According to the Centers for Disease Control, heart attacks account for one out of every four deaths in the U.S. each year.
88-year-old WWII veteran Sidney M. Kahn was one of hundreds who came to ETMC's free heart health fair Tuesday.
"The fact is I have a pacemaker and I spent three years in the military during WWII and I've had 13 surgeries since then. So, consequently I'm really concerned about my heart. And, that's what keeps us going."
Greg Murphy is director of Clinical Research at Tyler Cardiovascular Consultants. He says Kahn has good reason to be concerned.
"It's one of the leading causes of mortality, morbidity in East Texas."
And he says it's the leading killer in women.
"Women need to be screened more frequently, even, than men."
"We work out together. This is my workout partner."
20-year-old Andira Battles and her mother, Keffie, say teamwork keeps their hearts healthy.
"I have my days when I don't want to work out. And then, my mom's like, no, you're going."
Murphy says along with regular screenings, exercise and a healthy diet are also ways to avoid heart disease and heart attacks.
And, with Valentine's Day quickly approaching, now is the perfect time to start making sure you're heart healthy.
"There's nothing like love to make the heart healthy."
And he says a small amount of our favorite Valentine's Day treats can actually be good for our hearts.
"Dark chocolate, red wine..."
Both loaded with healthy antioxidants.
"Valentines, hearts, screening, health. It's what it's all about." says Murphy.
And of course, a little love- something this mother/daughter team uses to encourage each other all year round.
"She motivates me to stay young and healthy."


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Boonex Dolphin 7.1.3 Social Publisher module modification
This project received 3 bids from talented freelancers with an average bid price of $215 USD.Get free quotes for a project like this
Project Budget$30 - $250 USD
Total Bids3
Project Description
This project is to fix bugs SOCIAL PUBLISHER which was installed in Boonex dolhpin 7.1.3.
Social Publisher is the module easily publishes Dolphin activities and updates Dolphin status to other social networks: Facebook, Twitter, LinkedIn.
@ Fix fanction code of facebook/twitter/linkedin auth code in class of SOCIAL PUBLISHER to be able to complete posting on fb.twitter.linkedin.
@ FIx the function SOCIAL PUBLISHER checkout popup screen on content posting page.
@ add function to auto publish to Google+
More about SOCIAL PUBLISHER MODULE
Key Features-----------------------------------------------------------
@Publish Dolphin activities and update Dolphin status on Wall of Facebook / Twitter / LinkedIn
@Permission to connect / disconnect to Facebook / Twitter / LinkedIn to use Social Publisher.
@Auto connect to Facebook / Twitter in sign up process if User uses Facebook / Twitter account to log in
@Closely integrate Social Publisher into Social Connect
Front – End-----------------------------------------------------------
Auto link to social publisher in sign up progress
View screenshots: Link To Social Publisher Settings | Connect To Twitter
Permission user to publish Dolphin activity and Dolphin status when user posts something new on Dolphin Wall.
View screenshots: Choose To Publish Blog (Activity, Status)| Blog (Activity, Status) Was Published On Facebook Wall
Network Connections
View status of connections : Connect / Disconnect to Facebook / Twitter / LinkedIn
View screenshot: Network Connections
Activity Management
Allow users to set which modules will be published on Wall of Facebook / Twitter / LinkedIn
View screenshot: Activity Management | Hide Actions of Module In Activity Management
Back – End-----------------------------------------------------------
Activity Management
Set enable / default for modules what will be published on Wall of Facebook / Twitter / LinkedIn
View screenshot: Activity Management
Networks Settings
Facebook App ID
Facebook App Secret
Facebook App Key
Twitter Consumer Key
Twitter Consumer Secret
Update subject / content of message when user signs up
View screenshot: Network Settings
Supported Modules and Compatible Actions
Blogs: Create, Rate
Events: Add, Change, Join, Rate, Comment Post
Files: Add, Comment Post, Rate
Groups: Add, Change, Join, Rate, Comment Post
Map Profiles: Location Manually Updated
Photos: Add, Comment Post, Rate
Poll: Add, Answered, Rate, Comment Post
Sites: Add, Change, Rate, Comment Post
Sounds: Add, Comment Post, Rate
Store: Add, Change, Rate, Comment Post
Videos: Add, Comment Post, Rate
Bx Wall: Update
Profile: Edit, Set Membership, Edit Status Message
Skills Required
Looking to make some money?
- Set your budget and the timeframe
- Outline your proposal
- Get paid for your work
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- Forbes
- The New York Times
- Time
- Wall Street Journal
- Times Online


text: Step out in style this new season with these fabulous peep-toe wedge court shoes. Crafted from a shimmering fabric, these heels are the perfect addition to your S/S wardrobe. Featuring a cute peep toe, cork-effect wedged heel, and polished stud detail at the cuff. Complete your look with a midi dress and cropped jacket for instant chic appeal. Heel height: 9cm.Check stock and price


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Melanie @ The Rhythm Room
Though Melanie Safka may have fallen under the mainstream radar some time ago, she and her distinctive vocal style have remained a part of the collective consciousness. She's best known for "Brand New Key" (a song that every outspoken pre-teen girl should listen to, to feel both independent and unabashed) and "Lay Down (Candles in the Rain)," songs that encapsulate the spirit of '60s mass gatherings for a common cause. Her unmistakable voice is a series of seemingly contradictory characteristics: rough and sweet, fierce and inviting, strong and vulnerable, solid and shaky. While her most famous music and most memorable performances (including Woodstock, the iconic Isle of Wight Festival in England, and the Powder Ridge Rock Festival in Connecticut — which she played despite a court order saying the fest couldn't happen) occurred in the late '60s and early '70s, she's released a whopping 34 albums over the past 42 years. Her political candor and bold manner means that she isn't slowing down, even at 63 years old.
Related Location
1019 E. Indian School Rd.
Phoenix, AZ 85014
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text:
An Atlantic Monthly correspondent for over a decade, William Langewiesche obtained full access to the Ground Zero site to report on cleanup efforts after the September 11, 2001 terrorist attacks. His book on the subject is American Ground: Unbuilding the World Trade Center. Producer Ric Burns interviewed dozens of historians, journalists, artists, engineers and other experts during the making of New York: The Center of the World.
One Person's Story
The story of Pasquale Buzzelli is long and complicated. Typically it's full of confusion. He was one of those people who, for reasons essentially of confusion and not understanding what was going to happen -- no one did -- stayed in the buildings, sticking to -- He was a particularly well-behaved fellow, as were the others who stayed with him, sticking to the approved plan of -- you know -- wait for the evacuation order. So rather than leaving, as the great majority of people did, whether on their own initiative or on someone else's orders, these people stayed, fairly high in the North Tower, and then were caught by the collapse during a descent of the stairwells.
Buzzelli was approximately on the 22nd floor, I believe, or in that neighborhood. He was fairly high up in the building. He heard the collapse coming from above. It sounded to him like a boulder coming down on his head as the floors progressed, pancaking down successfully. Bam, bam, bam. He heard this thundering. And he didn't of course -- And he knew what was happening. He felt the building shaking. He was an engineer. He had this sort of clearheaded technical ability to -- and remained quite calm. He also instinctively ducked, as one would duck with a boulder coming toward one's head. And that's what it felt like to him. He went into a curl in a corner of the stairwell. And then it all fell apart around him, and he felt himself falling free. He kept his eyes closed. But he had all kinds of coherent thoughts, including that this was -- this reminded him of a ride in a amusement park -- I think, Great Adventure in New Jersey -- and how that "falling free" sensation was just like some big roller coaster. He had those thoughts. He was -- He felt the debris against his face as he was falling. And he saw with his eyes closed, he saw these bright flashes. He was being hit by pieces of debris. He was getting bright flashes... behind his closed eyes. Then there was a big final white flash, bright flash. And when he woke up, he was on top of the pile, on top of a huge slab. He, as far as he was concerned, hit the ground and woke up. The only thing is, it was two hours later. So he was out for about two hours. He had no memory or no concept of being out. But he knew exactly what had happened to him. And, I mean, the amazing thing about Buzzelli's story is that he was coherent about it. He could describe it in detail, what it was to fall-- during that collapse.
Beyond that, the amazing thing is that he survived by landing on top of the debris pile. So what was a peculiar thing in that collapse is that there -- the entire building beat him to the ground. It beat him to the ground in two ways. It -- Because of the peculiar pancaking nature of that collapse, top to bottom, systematically, by the time it caught up with him -- the collapse -- most of the building had in a sense already collapsed and was already at something close to its terminal velocity -- maybe not its theoretical terminal velocity, but as fast as it was going to get -- and passed him. Basically the building passed him on the way to the ground. And so, you know, he lost the race and survived. In fact, he had very little physical damage. I believe he broke his foot, and -- but he was stranded. Of course he was disoriented. He couldn't move. He was up high on a slab.
And then he -- And there was a long story full of fear and certainty of death, as fires approached. He looked up though, and he saw -- he couldn't understand what had happened before that even, that -- I mean, he knew the building had collapsed, but he couldn't -- he still couldn't understand, where was -- Where was the South Tower -- which by that time had already gone? Where was the North Tower? He saw sky and smoke and -- So there was a funny contradiction in that he both -- he was analytical and knew what had happened, and knew what was happening when it was happening to him, yet he couldn't get the consequences. It's just what we were talking about: that this death was too severe for him to fathom. So he's lying on this altar. He's having that confusion. There's no one around. It's utterly silent. There're no people around, nothing. It's a wasteland desert in the middle of New York City. The buildings are gone, there's smoke, and then there's fire.
At some point, he was quite certain -- to make a long story short -- that he was going to die from fire. So certain that he found a piece of jagged metal and was going to cut his wrists, in order not at least to burn to death. And had gotten to that point when he was rescued.
New York: The Center of the World examines the rise and fall of the World Trade Center -- from its conception in the post-World War II economic boom, through its controversial construction in the 1960s and 1970s, to its tragic demise in the fall of 2001 and extraordinary response of the city in its aftermath. It is the eighth episode of filmmaker Ric Burns' award-winning series New York: A Documentary Film.
While the U.N. debated strategies for control of atomic energy, the U.S. Navy was preparing for nuclear tests on Bikini Island.
The bizarre saga of the Symbionese Liberation Army and Patty Hearst's kidnapping and conversion to her captors' cause.
Meet the Wizard of Odd. Robert Ripley was a new media star and the most popular man in America.
The evocative stories of teenage hoboes crisscrossing America on trains during the Great Depression.
The effort of pioneering researchers to conceive babies through in vitro fertilization.
The internationally famous carnival of delights in New York was the birthplace of the hot dog and the roller coaster.
Roman Catholic priest Father Charles Coughlin used the power of radio to rail against the nation's economic system in the Depression.
Originally settled as a mail stop, Las Vegas changed from an Old West vacation town, to a mafia haven, to the "Atomic City" and "Sin City."


text:
Andrew, all the issues that you brought up were discussed a long time ago
before I had myself removed from the Phoenix. Not by choice. There was some
talk of polling the membership on issues, etc., etc., this esp came up when
there was a move toward preferred growers by the AHS.
Most people don't want to be involved in the nuts and bolts part of running
this organization because people like Kevin can tell you it is a lot of work.
You seem like a good candidate for the nuts and bolts effort, it is not hard
to get elected, rarely does anyone oppose someone who is running. Go for it.
To sign-off this list, send email to email@example.com with the
message text UNSUBSCRIBE HOSTA-OPEN


text:
Shifting Mindset: What About the Baby?Broward AWARE provides resources and information for safe and healthy experiences for children.
Video Hearings Challenged In Mental Health CasesPublic defenders look to have videoconference hearings in mental health cases blocked.
Instagram Filter You Pick May Reveal Your Mental HealthThe Instagram filter you choose may reveal more than you realize about your mental health.
Court Allows Lawsuit In Gun Dispute With SheriffAn appeals court cleared the way for a lawsuit alleging that the Palm Beach County Sheriff's Office improperly held onto a man's firearms.
Mental Health, Substance Abuse Reforms Get ApprovalIn the waning hours of the 2016 legislative session, Florida lawmakers Friday approved wide-ranging reforms to the state's mental-health and substance-abuse treatment systems.
Task Force Urges Doctors To Screen All Adults For DepressionAll adults, including pregnant women and new mothers, should be screened for depression as a routine part of health care, a government advisory group recommended Tuesday.
FIU Dean To Lead Study On Lead Exposure In ChildrenA new study on the effects of lead exposure on children's mental health will be lead by a dean at Florida International University.
Facing South Florida: A Look At Issues Important To People In South FloridaState Senator Anitere Flores, the chair of the Miami-Dade legislative delegation, will discuss the issues they will work on this year in Tallahassee.
Dade Judge Honored With Judicial Excellence AwardMiami-Dade County Judge Steve Leifman, who has long led efforts to change the way the legal system handles people with mental illnesses, was honored this week with the newly established Chief Justice Award for Judicial Excellence.
Study: Kids With Better Memories Are Good LiarsIs your youngster a good liar? It may not be such a bad thing, research shows.
NFL Player Retires At Age 24 Over Concerns Of Head TraumaAs more and more cases of current and former NFL players having head issues come out, the more those players are taking note of the dangers of playing the sport.
Cooking Classes Could Help People Cope With Mental Health ProblemsSome counselors, treating patients with issues such as stress, anxiety and depression, are turning to cooking classes to help them cope with mental health problems.


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The long term goal of this application is to elucidate the in vivo significance and molecular mechanisms of integrin-mediated activation of transforming growth factor beta (TGFbeta). In current and previous cycles of this grant we have shown that the integrin, alphavbetaS, activates TGFbeta and that this process plays a central role in models of pulmonary fibrosis and acute lung injury in mice. We have also identified three stimuli, thrombin, LPA and S1P that can each activate this process be initiating signals from G protein coupled receptors. In this application we propose to first determine the importance of this pathway in a more clinically relevant model of acute lung injury that combines low dose LPS with normal tidal volume ventilation. For these experiments we will also determine whether any protection seen with loss or blockade of the integrin is specifically due to loss of the integrin from alveolar epithelium and/or to loss of TGFbeta activation using mice we have generated expressing either the integrin or active TGFbeta as alveolar epithelial transgenes. In parallel, we will explore the mechanisms underlying indcution of this process through activation of G protein coupled receptors. We will use cells from mice lacking Galpha12, Galpha13 or Galphai and shRNA designed to knockdown each subunit to identify the G proteins involved in these responses. We will take a similar approach to identify the relevant LPA and S1P receptors. To genetically determine the relevance of actin-myosin mediated contraction, and to identify the specific myosin isoforms invovled, we will also use shRNA-mediated knockdown of each of the three myosin II isoforms we have identified in lung epithelial cells. To determine the significance of cell contraction we will also quantify alphavbeta6-medated TGFbeta activation by cells plated on substrates of varying stiffness. Finally, we will use labeled forms of the integrin and a TGFbeta receptor to perform live videomicroscopy and test the idea that this process involves the formation of a TGFbeta activation synapse across adjacent cells. Lay summary: This application seeks to understand a key process that controls pulmonary fibrosis and acute lung injury, two common and currently largely untreatable diseases. By determining the mechansims by which cells in the lung control this process, we should be able to identify and validate novel targets for design of effectiive treatments for these diseases.
|Erle, David J; Sheppard, Dean (2014) The cell biology of asthma. J Cell Biol 205:621-31
|Sheppard, Dean (2013) ROCKing pulmonary fibrosis. J Clin Invest 123:1005-6
|Friedman, Scott L; Sheppard, Dean; Duffield, Jeremy S et al. (2013) Therapy for fibrotic diseases: nearing the starting line. Sci Transl Med 5:167sr1
|Su, George; Atakilit, Amha; Li, John T et al. (2013) Effective treatment of mouse sepsis with an inhibitory antibody targeting integrin *v*5. Crit Care Med 41:546-53
|Giacomini, Marilyn M; Travis, Mark A; Kudo, Makoto et al. (2012) Epithelial cells utilize cortical actin/myosin to activate latent TGF-* through integrin *(v)*(6)-dependent physical force. Exp Cell Res 318:716-22
|Hogmalm, Anna; Sheppard, Dean; Lappalainen, Urpo et al. (2010) beta6 Integrin subunit deficiency alleviates lung injury in a mouse model of bronchopulmonary dysplasia. Am J Respir Cell Mol Biol 43:88-98
|Melton, Andrew C; Bailey-Bucktrout, Samantha L; Travis, Mark A et al. (2010) Expression of *v*8 integrin on dendritic cells regulates Th17 cell development and experimental autoimmune encephalomyelitis in mice. J Clin Invest 120:4436-44
|Atabai, Kamran; Jame, Sina; Azhar, Nabil et al. (2009) Mfge8 diminishes the severity of tissue fibrosis in mice by binding and targeting collagen for uptake by macrophages. J Clin Invest 119:3713-22
|Singh, Purva; Chen, Chun; Pal-Ghosh, Sonali et al. (2009) Loss of integrin alpha9beta1 results in defects in proliferation, causing poor re-epithelialization during cutaneous wound healing. J Invest Dermatol 129:217-28
|Xu, Ming Yan; Porte, Joanne; Knox, Alan J et al. (2009) Lysophosphatidic acid induces alphavbeta6 integrin-mediated TGF-beta activation via the LPA2 receptor and the small G protein G alpha(q). Am J Pathol 174:1264-79
Showing the most recent 10 out of 20 publications


text:
Tuna Cakes with Spring Onion Salsa
|Peeled and diced potatoes
|14 Ounce (400 Gram)
|Canned tuna chunks
|185 Gram, drained and flaked roughly (In Brine Or Spring Water)
|Lemon juice
|1 Teaspoon
|Olive oil
|1 Teaspoon
|To Taste
|Ground black pepper
|To Taste
|For the salsa :
|Spring onions
|4 , chopped finely
|1 Inch, seeds removed and flesh diced finely (1 Number)
1. In a saucepan boil the potatoes in lightly salted water for 15-20 minutes, until tender.
2. When the potatoes are just cooked through, drain and mash them.
3. In a small bowl mix together all the salsa ingredients and leave to marinate.
4. Into the mashed potatoes stir tuna, the remaining lemon juice and season to taste.
5. Divide the mixture into eight and shape into small cakes.
6. In a large, non-stick frying-pan heat oil and fry the cakes for 3 minutes.
7. Gently turn them over and cook for a further 2 minutes.
8. Serve two tuna cakes per person with a helping of salsa.
Recipe Summary
Rate It
Nutrition Rank
Nutrition Facts
Serving size
Calories 202 Calories from Fat 46
% Daily Value*
Total Fat 5 g7.8%
Saturated Fat 0.89 g4.4%
Trans Fat 0 g
Cholesterol 8.3 mg2.8%
Sodium 286.5 mg11.9%
Total Carbohydrates 21 g7.1%
Dietary Fiber 2.8 g11.2%
Sugars 0.4 g
Protein 16 g32.2%
Vitamin A 3.7% Vitamin C 5.8%
Calcium 1.8% Iron 11.7%
*Based on a 2000 Calorie diet


text:
Gerard Gioia, PhD, Director of the Safe Concussion Outcome Recovery and Education (SCORE) Program at Children's National, sits down with National Geographic to discuss how concussions affect the brain and what symptoms parents should look for to help identify a concussion.
Read the article
Want the latest Children's National news and stories as they happen? Sign up to get our News & Events releases by email.
Children's National has some of the world's foremost experts in care for children with complex neurodevelopmental disorders affecting the brain and central nervous system.
Learn more about the concussion awareness partnership between Children's National and MedStar Sports Medicine.
Learn how to spot and treat a concussion, whether you're a parent, teacher, physician, or coach.
Gerard Gioia, PhD, with Children's National, demonstrates new youth concussion smart phone application that puts CDC youth concussion guidelines into parents' and coaches' hands.


text:
Added lots of black...paint Grizzly wheels next?
Started with soft top and factory half doors...removed soft top...bought diamond plated chrome-colored doors (painted them black)...painted roll bar padding black (thanks to this forum found great paint)...installed mirror relocation brackets with stock mirrors (major PITA after dropping windshield and dash)...installed Bestop rear seat cover (which is an unbelievably nice seat cover)...painted soundbar black (which came out surprisingly nice).
See before, middle, and after pics below...
I've seen people paint these Grizzly wheels black, although they are already a dark grey...how do you think they would look?
looking good might as well do the wheels also
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text: Seller: stuffednfeathereduk (7) 100%, Location: Taunton, Ships to: Free Local Pickup, Item: 132012004857 This chair would make an excellent upholstery project 47 cm wide 53 cm deep 94 1/2 cm high and 30 cm height to If you need a courier please see below under collections Most of the items I sell are pre owned and will have signs of age related wear e.g the odd scratch or fading, please make sure you take a look at all the photos, as they do form part of the description and will give you a good idea of colour and condition. We do try to list or show any known defects or faults though we are only human and mistakes are sometimes made, if so we will try to resolve the problem as quickly as possible. VIEWING:- Most of the items listed are stored at our warehouse near Taunton, if you would like to view an item please contact me to arrange an appointment, we also have various lights fitting / chandeliers, China etc PAYMENT :- 24hrs of the listing ending via Paypal, bank transfer, if your collecting in person cash on collection is fine, please let me know. COLLECTIONS :- Please ensure arrangements for collection have been made within 7 days of the listing ending, and collection within 14 days unless agreed otherwise, items not collected within 14 days will be re-listed. As with all the items listed, you are welcome to collect in person or feel free to arrange your own courier, I will try and help as much as possible with packing though there maybe an additional cost for this, please check with me before purchasing an item. If you need a courier try Norton CRC (Darren) on 077 860 15211 local to us or try shiply, the link is at the end of the listing Please feel free to use whoever you like Sorry but I cannot not be held responsible for items damaged whilst in transit you will need to deal with the courier direct should this be the case. Any questions please don't hesitate to ask Thank you for looking On 23-Nov-16 at 23:17:50 GMT, seller added the following information: For delivery quotes of up to 75% off standard rates - try Shiply: I want to put this into my own eBay listings


text:
Lenalidomide as Consolidation and Maintenance in Adults >/= 60 Years of Age With AML Following Standard Induction
This study is currently recruiting participants. (see Contacts and Locations)
Verified February 2017 by UNC Lineberger Comprehensive Cancer Center
UNC Lineberger Comprehensive Cancer Center
Information provided by (Responsible Party):
UNC Lineberger Comprehensive Cancer Center
ClinicalTrials.gov Identifier:
First received: April 13, 2012
Last updated: February 17, 2017
Last verified: February 2017
- Full Text View
- Tabular View
- No Study Results Posted
- Disclaimer
- How to Read a Study Record
No Study Results Posted on ClinicalTrials.gov for this Study
|Study Status:
|This study is currently recruiting participants.
|Estimated Study Completion Date:
|February 2019
|Estimated Primary Completion Date:
|April 2018 (Final data collection date for primary outcome measure)


text:
Search By Vehicle
K&N Engine Cold Air Intake Performance Kit 57-9005 87-92 TOYOTA SUPRA 3.0L TURBO FIPK KIT
Performance Intake Kit
K&N's easy to install air intake systems replace the restrictive factory air filter and air intake housing allowing for virtually unrestricted air flow. This power gaining air intake comes with K&N's famous million mile limited warranty.
The K&N 57-9005 FIPK air intake system replaces the restrictive factory air filter and air box in some older Toyota Supra models. K&N intakes are designed to dramatically reduce intake restriction and improve air flow. This allows your engine to inhale a larger amount of air than the factory air filter assembly. More air means more usable power and acceleration throughout the engine's RPM range. The 57-9005 air intake comes with a chrome topped K&N high-flow air filter that installs onto the factory mass air sensor within the previous air box space. Air is directed through the air filter into the engine's throttle body for a guaranteed power gain. The oversized cone shaped air filter can be used for up to 100,000 miles before servicing is needed depending on driving conditions. This air intake is relatively easy to install usually in 90 minutes requiring commonly available tools to do the job. K&N 57 Series FIPK's are street legal in all 50 US states and come with K&N's Million Mile Limited Warranty.
Extended Information
- 1
- 8421310000
- 2 Available to Order
- 57-9005
- 57-9005
- 24844021687
- Ships from Manufacturer Typically in 1-3 Business Days, Depending on Availability!
- New
Shipping Information
- Item Requires Shipping
- 3.5 lbs.
- W9.1250" x H9.2500" x L9.1250"
Customer Reviews
Total Reviews (0)
Write the First Review!
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The goal of the Transgenic Animal Core is to assist the investigators of each project with the design, production, characterization, and maintenance of genetically modified mice. To achieve this goal, the core will perform the following functions. First, the core will design and construct transgenes and develop genotyping assays and purify transgene DNA for microinjection. Second, the core will generate transgenic founders via microinjection of transgene DNA into fertilized eggs from the C57BL/6 strain of mice. Potentially transgenic offspring will be identified using genotyping assays developed by the core. Founder mice will be characterized for the ability to transmit the transgene to offspring. The number of independent chromosomal integration sites in each founder will be determined. Germline-competent mice, each with a transgene integrated at a single genomic locus, will be delivered to project leaders. The third service of thecore will be to design and facilitate production of gene-targeted mice. Specifically, the core will produce and purify the gene-targeting constructs and test embryonic stem (ES) cell screening assays. The core will then work with an off-site ES cell facility to introduce the DNA into ES cells and isolate appropriately targeted ES cell clones. Appropriately targeted clones will then be used for blastocyst injections. Chimeric mice will be sent to UAMS and the core will identify those with the ability to produce offspring harboring the targeted allele. Germline-competent mice will then be delivered to project leaders. Finally, the core will assist in the characterization, maintenance, and preservation of genetically-modified mice. Quantitative reversetranscriptase polymerase chain reaction (RT-PCR) assays will be designed to specifically detect transgene mRNA and then used to determine the tissue distribution of transgene mRNA expression. Expression patterns of each Cre-deleter strain will be verified by crossing with R26R Cre-reporter mice. Each new mouse model generated by the core, or imported for use by the program, will be cryo-preserved via sperm cryopreservation for long-term bio-security, cost-reduction, and efficient access.
Genetically modified mice allow investigators to determine whether phenomena observed in cell lines and cell cultures also occur in vivo. Such mice are also used to test hypotheses that cannot be convincingly addressed in any in vitro system. Thus timely and efficient production of genetically modified mice is essential to the overall goal of the Program which is to improve the understanding of the pathophysiology of the bone fragility syndrome of osteoporosis and thereby rationalize and optimize its treatment.
|Bartell, Shoshana M; Kim, Ha-Neui; Ambrogini, Elena et al. (2014) FoxO proteins restrain osteoclastogenesis and bone resorption by attenuating H2O2 accumulation. Nat Commun 5:3773
|Xiong, Jinhu; Piemontese, Marilina; Thostenson, Jeff D et al. (2014) Osteocyte-derived RANKL is a critical mediator of the increased bone resorption caused by dietary calcium deficiency. Bone 66:146-54
|Iyer, Srividhya; Han, Li; Bartell, Shoshana M et al. (2014) Sirtuin1 (Sirt1) promotes cortical bone formation by preventing ?-catenin sequestration by FoxO transcription factors in osteoblast progenitors. J Biol Chem 289:24069-78
|Bellido, Teresita (2014) Osteocyte-driven bone remodeling. Calcif Tissue Int 94:25-34
|Manolagas, Stavros C (2014) Wnt signaling and osteoporosis. Maturitas 78:233-7
|Jilka, Robert L; O'Brien, Charles A; Roberson, Paula K et al. (2014) Dysapoptosis of osteoblasts and osteocytes increases cancellous bone formation but exaggerates cortical porosity with age. J Bone Miner Res 29:103-17
|Manolagas, Stavros C; Kronenberg, Henry M (2014) Reproducibility of results in preclinical studies: a perspective from the bone field. J Bone Miner Res 29:2131-40
|Plotkin, Lilian I; Bellido, Teresita (2013) Beyond gap junctions: Connexin43 and bone cell signaling. Bone 52:157-66
|Onal, Melda; Piemontese, Marilina; Xiong, Jinhu et al. (2013) Suppression of autophagy in osteocytes mimics skeletal aging. J Biol Chem 288:17432-40
|Zhou, Jian; Ye, Shiqiao; Fujiwara, Toshifumi et al. (2013) Steap4 plays a critical role in osteoclastogenesis in vitro by regulating cellular iron/reactive oxygen species (ROS) levels and cAMP response element-binding protein (CREB) activation. J Biol Chem 288:30064-74
Showing the most recent 10 out of 133 publications


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Dec 12, 2008, 10.50 AM | Source: Moneycontrol.com
The markets have crashed in early trade following a slump in Asian stocks and US futures, and failure of the US auto bailout to clear the Senate. Auto, real estate, capital goods, power, metal, banking, and technology stocks are under pressure.
Like this story, share it with millions of investors on M3
Mkts plunge as US auto bailout fails, weak global cues
The markets have crashed in early trade following a slump in Asian stocks and US futures, and failure of the US auto bailout to clear the Senate. Auto, real estate, capital goods, power, metal, banking, and technology stocks are under pressure.
At 9:56 am, the Sensex fell 334 points to 9,311 and the Nifty lost 97 points to 2,822.
Major losers are M&M, Tata Motors, Maruti, DLF, Ashok Leyland, Jaiprakash Associates and Bharat Forge.
Among the US markets futures, Dow Jones and Nasdaq Futures tumbled 4%.
In an interview with CNBC-TV18, JP Morgan said US Auto bailout failure is negative message for global capital markets. This move will stall rally and bad for auto ancillaries & financials, he said.
Asian markets also extended losses further, after that bad news on auto bailout. Japanese Yen appreciated to 89.27 to a dollar.
Nikkei, Kospi, Taiwan and Hang Seng plunged 5.5-7%. Shanghai and Straits Times are down 1.7-3.4%.
In US markets, stocks closed sharply lower led by financials after comments from JP Morgan CEO Jamie Dimon on the fourth quarter. It was a bad day for economic data too, jobless claims stood at a 26-year high. October trade deficit widens more than expected while import prices drop more than expected. The Dow Jones plunged 196.33 points, or 2.24%, to 8,565.09. The S&P 500 index declined 25.65 points, or 2.85%, to 873.59, and the Nasdaq composite index fell 57.60 points, or 3.68%, to 1,507.88.
Market cues:
Uncertainty looms over auto bailout pkg
Initial jobless claims at 26-year high, trade deficit grew by 1.1%
CNBC-TV18 poll sees IIP for Oct at 1.68% versus actual no of 4.8% (MoM), 12.22% (YoY)
Crude surges over 10% as OPEC President pledges substantial output cut
FIIs net buy USD 245 million in equity on December 10
MFs net buy Rs 167 cr in equity on December 10
F&O Open Int up by Rs 748 crore to Rs 53,381 crore
F&O cues:
Nifty down 0.3%, Futures Open Int flat, Nifty Fut trades at 9 pts prem
Stock Futures add 58.5 lakh shares in Open Int; added 7.5 crore shares in last 3 days
Nifty Open Int PCR down from 1.31 to 1.3
Nifty Puts add 3.7 lakh shares & Calls add 5.5 lakh shares in Open Int
2900 Call adds 4.6 lakh shares in Open Int
2800 Put adds 1.8 lakh shares in Open Int
2900 Put adds 1.5 lakh shares in Open Int
3200 Call sheds 2.7 lakh shares in Open Int
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|Nicola Ken Barozzi <nicola...@apache.org>
|Re: latest forrest can't build incubator site
|Wed, 01 Sep 2004 11:50:43 GMT
Rodent of Unusual Size wrote: ... My apologies for the problems Forrest is giving the Incubator Project. I feel responsible for it, having proposed it in the first place. I think that Forrest has been a serious problem for active collaboration on the site, and wish to fix this. If this does not happen in a reasonable time, I'll personally ask to drop it's usage till it becomes more usable for this purpose. Now on to the replies... (let's continue this thread on the forrest dev list) > that makes it better.. but it does *not* restore the appearance > we had/{want?}. observe the difference between what we have/want: > > http://cvs.apache.org/~coar/i.a.o-before.png > > and what the above change gives us: > > http://cvs.apache.org/~coar/i.a.o-after.png This is a new version of the skin that was used before. The changes were made to use more CSS and make the fonts smaller (the size is customizable), as many have complained that they were too big (especially in navigation). It is unfortunate that we are also now deciding to do another change in the skin format, to make it fully css-based... > specifically: > > 1. the tab (shape,font,size,highlighting} is substantially different. > 2. the print/pdf icons in the upper right have been shrunken to things > barely recognisable. > 3. the text in the 'search' box has changed from white to black, > reducing readability. > 4. worst of all, the body has changed so that it now has a toc at the > beginning, pushing the meat of the page down. This last point is configurable in skinconf.xml... the TOC can be set to less levels or disabled. (IIRC the <toc> element) Another unwanted backwards incompatible change :-/ ... > which leads > ** me to be concerned that making that change, which should make the > ** derby page look like the 'after' picture, will break *other* pages > ** already on the site. The whole site has to change AFAIK unfortunately. > i really appreciate the improvement, but what do we need to do to regain > our original look-and-feel? We have deleted the old skin as it does not use the new Forrest features. As it seems this is not well seen by our users. I'll see if we will decide to revert this "imposed" skin upgrade. > i'm not sure i entirely buy the 'was built with 0.5.1' argument, since > ian holsman supposedly built the looked-right derby page on his own machine > using 0.6-dev, with no skin/config changes, and then uploaded it. 0.6-dev has changed fast in the skins lately, so it could just be that he used a previous 0.6-dev version. ... > this is not a slam against forrest by any means; i love forrest's potential. > if anything, it's a criticism of the choice to use it for the i.a.o site, > which is maintained largely by forrest non-users. forrest is a moderately > complex beast, and is still evolving. someone (presumably whomever was > originally so gung-ho for forrest that it set up/converted the i.a.o site > to use it) should track the changes to forrest that are going to affect our > use of it, and make appropriate modifications to the i.a.o site. That's me IIUC... the fact is that we are trying to make it totally backwards compatible, and I thought that it still was. It seems that the forced skin change is the major culprit. > i don't > think it's unreasonable for everyone updating the i.a.o site to know how to > *use* forrest (update-pages-and-go), but i *do* think it's a bit over the top > to expect them to know how to configure it and know what changes to make > to track forrest's own evolution. Of course. These problems have come up because Forrest (the project) has been very bad at releasing, and this has forced me to use the dev version to update the site. We have decided new rules and dates for releasing, so after 0.6 the Incubator can saftely generate the site with a fixed version. > moving on to how-to questions concerning the cwiki format: You can find a reference here: http://forrest.apache.org/docs/wiki-sample.html As for *.cwiki, it seems to be creating issues instead of just being a simple format, as it gives validation problems without being able to be validated. Would a change to using plain *.html (still digested by Forrest) be a better option? > 1. is there any way to create a prominent box for important notes? Nope. > 2. is there any way to include [url] and ''italic'' inside a table? > (those seem to end the table def) Not AFAIK. > 3. how does one signal bold text? __text__ -- Nicola Ken Barozzi email@example.com - verba volant, scripta manent - (discussions get forgotten, just code remains) ---------------------------------------------------------------------
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