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CodePlexProject Hosting for Open Source Software
Oct 19, 2016
4:58 PM(11 posts)
first post: Lukiya wrote: Can you add vs2015 support?
Oct 6, 2016
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first post: mtsatria wrote: In visual studio 2015 with version 2.0.2 r0, the generated xsd file...
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first post: mmilchuk wrote: I have been using the Config Section Designer since Visual Studio 2...
Mar 13, 2015
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first post: simone86 wrote: This seems an old problem and I see that you have talked about it i...
Jan 22, 2015
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first post: MarkosCP wrote: Hi,
Is there anyway to utilise / pass in a configuration section ...
Nov 25, 2014
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first post: michaelchedra wrote: Hi,
This is a brilliant add on, it's saved me hours of work and r...
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first post: simone86 wrote: I would like to have more than one section inside my config...
I h...
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first post: kelmen wrote: I have designed the csd.
I read that there's a feature to generat...
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first post: andym1978 wrote: After doing some work on a very large configuration management proj...
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first post: janimatyastct wrote: First I would like to send a big Thank You for everyone participati...
Unanswered only


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Hyltor Hotel
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Massive Shopping center and cooling mists
... the coast so there was no breeze at all it was inland.
Kyle surprised me with my first charm for the Pandora bracelet he brought me for Christmas! its adorable and im really really happy with it - it looks so cute!
For our last night in La mata we decided to go back to My dream to have a beautiful meal and say thank you to the amazing staff for really looking after us every time we went - Its sad as i will miss the laughs and the food!
Long day travelling
After a long night on the bus, I arrived early in Munich where I went back to ,y hostel that I stayed at earlier in my trip. I went and had breakfast, although as It was the start of the Oktoberfest so there was a lot of ladehosen! I had breakfast and then when the time was right made my way to the airport. After along tram right I arrived where the process was very easy and managed to board my flight where I was then picked up by dad at the other ...
Day 10 Spain
... going to the same shopping centre as we did in the very first day we got the car! We grabbed some yummy burgers for a late lunch and looked around but nothing was open! So funny how the shops are shut on Sunday's! We headed back to the hotel and that was literally all we did today haha!! What a lazy ...
Day 9 Spain!
We headed down the road to McDonald's for breakfast!! I don't know what it is but the bacon and egg mcmuffins are so tasty here!! I don't no if it is because they look like they make them with love, taking there time do to everything perfectly or if it is because we hadn't had them for soooo long now haha!!! We then came back to the hotel and hung out for a few hours using up ...
Day 8 Spain!
... park to our room in the lift! We then chilled out in the room for a little bit before setting off down the road to the mall! We found this great looking Italian restaurant and decided to have a late lunch/early dinner there! We had an entree, main, dessert and soft drink for €10!! Bargain! It was so yummy to! The dessert was the best part though chocolate fondant!!!!!! We then did a little bit of shopping with heaps of sales!! Love a bargain!! ...


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I've been so busy with work that it's been a while since I've posted anything. This is an older piece I did that I thought I'd share.
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If you're looking for a challenging and scenic Chicago area golf course, then Water's Edge is for you. Designed by Rick Robbins and PGA Consultant Gary Koch, this golf course is 18 holes of championship golf that is as challenging as it is scenic. Robbins is known for designing playable courses and Water's Edge is no exception. Measuring 6904 yards from the back tees and 5332 yards from the forward tees, golfers of every skill level will enjoy a day at Water's Edge. And with lush natural grasses, protected wetlands and dense forest golfers will remember this upscale, par 72 as one of the most beautiful courses in the Chicagoland area.
A multipurpose open play area, Woodridge Town Center hosts a variety of festivals in Woodridge.
The Cinemark Imax experience is a 5-story tall, 7-story wide version of educational and recreational film subjects of both 2-D and 3-D.
Includes three ice surfaces, public skate 7 days a week, learn-to-skate and hockey classes, observation area, off-ice training center, party/conference rooms, arcade and a pro shop.
The 1st full service, fully integrated restaurant, bar and movie theater to open in the area. Each auditorium features terraced seating with high-back executive leather chairs.
Carrabba's Italian Grill - Woodridge
"At Carrabba's, we bring you the same wonderful experiences we grew up on--from our warm Italian hospitality to the authentic aromas in our open kitchen, to our flavorful handmade recipes passed down for more than four generations." -Johnny Carrabba
Bobak's Signature Events and Conference Center
Bobak's is a unique banquet conference facility for corporate, social and family events. Whether you are looking to plan a wedding reception, corporate function or birthday party, expert Event Specialists will work closely with you to ensure that your day is a success. From intimate to exclusive, Bobak's first-rate banquet & meeting facilities, award winning cuisine and unparalleled service will transform your event to extraordinary!
Village Greens of Woodridge golf course, located in Woodridge, Illinois, features an 18-hole, fun, affordable, public daily fee golf course always in great condition and considered one of Chicago's best value for golf. Golfers find Village Greens tree-lined fairways and golfer friendly atmosphere an ideal layout.
Seven Bridges Golf Club, a 4-Star rated course by Golf Digest, provides a golf experience unlike any other. Seven Bridges is recognized as one of the top 5 public courses in the Chicagoland area. It's a public course with a private course feel. Our finely-manicured course boasts a bucolic setting featuring 100-year-old oaks, picturesque lily pad ponds, and, of course, at least seven bridges. Following your round, you can enjoy a meal and drinks at the best 19th hole setting anywhere, The Dock, which offers great dining and sunset views.
Country Cape Cod style home offering charm and hospitality overlooking six acres of horse pasture.
Penny candy, gourmet chocolates, candies, Jelly Bellys, soup, sandwiches, ice-cream, pop, coffee and cappuccino.
Home to catfish, walleye, northern pike, bass, pan fish, picnic and recreation.
This site's 5,500 acres make up one of the largest and most used hunting and field trailing areas in the state. It also offers camping, picnicking, boating, fishing, two small natural areas and 12 miles of equestrian trails with cross-country jumps.
Largest open space in northeast Illinois.
Multi-dealer. 15,000 sq. ft., full line antiques and collectibles.
Multi-dealers, general line antiques, collectibles, Hallmark ornaments, Fenton candles, souvenirs, country soaps and dips.
Euorpean imports, estate jewelry, general line. Three buildings with thousands of choice items.
Furniture, costume jewelry, vintage clothing, glass, pottery, Yankee candles, linens.
General line antiques and collectibles. Multi-level, multi-dealer. We buy estates.
Seasonal, monthly camping and full hook-up. Full hook-up sites to primitive tenting. Beach, fishing, fossil hunting, playground, showers. Near raceways. Shade. Open all year. Call for reservations and hours of operations.
The Gemini Giant is a landmark statue on U.S. Route 66. The 30 foot tall statue is named after the Gemini space program and holds a silver "rocket ship" in his hands, while sporting an astronaut's space helmet that looks more like a welding mask.
The Mar Theatre opened for business on June 15th 1937, and today much of the original stage and decorative ceiling are intact. The lobby and ticket booth area are in the original configuration. Much of the original architectural hardware and lighting fixtures are still in use. The original auditorium comfortably seats 300 moviegoers and a new second auditorium accommodates 64 patrons. Outside the original marquee is still used to inform moviegoers of the current movies.
A collection of what's old, some new, and every bit of custom and unique while keeping prices respectable and providing a comfortable, welcoming atmosphere for shoppers. Chances are you might even run into the Two Hounds, beagles Annie & Cooper.
Wilmington Downtown Merchants Association
Stop and visit Wilmington, IL an old mill town built directly on the river with the charm and hospitality you won't find anywhere else. Located on Route 66, you'll find a variety of antique and specialty shops and great restaurants.


text:
7 nights with an arrival from
This old Tuscan country house is set in beautiful countryside with forests, vineyards and slopes full of gnarled olive trees. The house was renovated faithfully and lovingly, taking care to preserve both the layout of the rooms and the structural characteristics.
The rooms have a high ceiling height; the ceiling supported by exposed beams. The floors are decorated with beautiful tiles terracotta clay.
Overall, the house, its original style is set according to, simple and cozy. From the windows you have a beautiful view of the surroundings.
|Internet code


text: Badass Historical Chemists: The Inventor of a Green Dye That May Have Killed NapoleonEsther Inglis-Arkell11/23/15 10:40am51EditPromoteGo to permalinkIf anyone tells you that all you need to do to succeed is work hard, just mention Carl Wilhelm Scheele. They'll say, "Who?" And your point will be proved. This may be the most accomplished chemist never to get credit for anything — except possibly accidentally killing a dictator.


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Get an alert when new Mugenkyo Taiko Drummers dates are announced
Mugenkyo Taiko Drummers are the UK's first and only professional touring taiko group and Europe's most established performing company in this fast expanding field.
Mugenkyo present taiko in a modern and theatrical style with precise choreography, dramatic lighting and a variety of costumes ranging from the post-apocalyptic industrial to gorgeous earthy silks.
The concert is extremely musically varied; powerful rhythms, huge taiko drums, delicate shinobue bamboo flute, expressive percussion and dance.
'Just when you think it could not get any more powerful, it doubles in intensity. This show is not one to be missed' (Edinburgh Evening News).
See more info at taiko.co.uk
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Thursday, February 23, 2017
Working with Phyllis Diller (Sort of!)
As I write this, the media is abuzz with news of the passing of two Hollywood figures that were in their own ways legends: Phyllis Diller and director Tony Scott. Phyllis died of natural ... Continue Reading →
Rules, Categories Updated for 40th Annual Annie Awards
ASIFA-Hollywood has announced the rule and category changes for the upcoming 40th anniversary edition of the Annie Awards. Changes to the rules and categories this year include: Achievement ... Continue Reading →
The Most Shocking Cartoon Ever Made!
If the Annie Awards ever decided to create a category for Outstanding Achievement in Horrifyingly Bad Taste in Animation, 1989's Quiet Please would be the hands-on winner. Nearly ... Continue Reading →
'Gumball' Returns to Cartoon Network on August 14
Cartoon Network's acclaimed animated media series The Amazing World of Gumball will begins its second season on the air on August 14 at 7 p.m. The mixed-media show which won a BAFTA ... Continue Reading →
Toon Legend June Foray Wins Her First Emmy
Dynamic voice actress June Foray finally took home her first Emmy last night at age 94. The animation legend, who is best known for voicing Rocky the Flying Squirrel in the Rocky and ... Continue Reading →
'Rango,' 'Hugo' Win Big at VES Awards
Gore Verbinski's underdog hero Rango continued its winning streak last night at the 10th Annual VES Awards. Only a few nights after taking home four Annie Awards, the Paramount/ILM ... Continue Reading →
'Rango' Rides Home with Top Annie Prize
In what may be a bellwether for Oscar night, Paramount/Nickelodeon's quirky CG-animated feature Rango won the prize for Best Picture at the Annie Awards this Saturday (Feb.4). The ... Continue Reading →
Patton Oswalt to Host 39th Annual Annie Awards
Patton Oswalt, the voice of Remy, everyone's favorite rat chef in Pixar's Ratatouille, will be the host of this year's 39th Annual Annie Awards on Saturday, Feb. 4 at UCLA's ... Continue Reading →
You're Goin' to the Moon, June?
If there is anyone in the animation field who truly needs no introduction, it is June Foray. The First Lady of Animation has accomplished so much in her long and varied career—which ... Continue Reading →
Annies' Facebook Contest Offers Super Pixar Prize
Do you think you can guess the winners of the upcoming Annie Awards? The folks at ASIFA-Hollywood, the org behind the annual Annie Awards have launched the perfect contest for toon ... Continue Reading →


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Wego.com.sg recently found 5 hotels in Logansport, United States. Book last minute hotel or find great hotel deals such as Holiday Inn Express & Suites LOGANSPORT for S$181 per night. Save more on cheap hotels with rates from as low as S$105 per night.
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text:
Catalogue Number: T8R-8K66
- Author: Mary M. Firth,Andrew G. Ralston
- Format:Paperback
- Publisher:Hodder Education
- Published:31 October 2003
Sorry, there are currently no sellers for this product.
Product description
- Total Pages: 120
- Genre: Educational: English language: reading & writing skills
- Secondary Genre: Educational: English literature
- Illustrations: 30 illustrations
Close Reading 11-14 provides a wide selection of of extracts from novels old and (especially) new, with accompanying interpretation comprehension-type questions. In addition, the 'Taking A Closer Look' section in each chapter focuses on a specific language feature from the passage and provides further explanations and practice exercises on that aspect of language. The book has specific links with Knowledge About Language (by the same authors) but can also be used independently of that title, either as a stand-alone classroom textbook or a resource for individual pupils needing interpretation practice.
Author's Biography
Mary M Firth and Andrew G Ralston teach in one of Scotland's top schools and are highly successful authors of several English language and literature titles written primarily for the Scottish market.


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|Message view
|« Date » · « Thread »
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|"Shapira, Yoav" <Yoav.Shap...@mpi.com>
|RE: Tomcat 4.1.30 not shutting down correctly
|Wed, 27 Oct 2004 15:48:59 GMT
Hi, >tc 1.3 was ment to read tomcat 3.3.2. Ahh, OK. I've never used 3.x so I can't help much there. >But if you know what would cause to Tomcat window to persist after >shutdown, I'd be interested in knowing your views. Non-daemon threads spawned by your app (or a library used by your app) and not terminated properly on webapp shutdown would do this. It's fairly common. Yoav This e-mail, including any attachments, is a confidential business communication, and may contain information that is confidential, proprietary and/or privileged. This e-mail is intended only for the individual(s) to whom it is addressed, and may not be saved, copied, printed, disclosed or used by anyone else. If you are not the(an) intended recipient, please immediately delete this e-mail from your computer system and notify the sender. Thank you. --------------------------------------------------------------------- To unsubscribe, e-mail: email@example.com For additional commands, e-mail: email@example.com
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text:
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We have years of experience in creating cinematic videos in Winter Park. Contact Perfect Sky Productions today for the best Training videography services in town.
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Our project delivery partner, Trinity Project, have been appointed as executors of Thembi's late mother's estate. This allowed us to evict the relatives who had been illegally squatting there, and return the house to Thembi and her child. However, we now have to 'administer' the estate of her late mother in order to give Thembi legal ownership of the house, and the long term security this will ensure.
Due to the nature of this case, administering the estate of Thembi's late mother involves many costs which neither Thembi, ZET, or Trinity Project have the capacity to cover. This micro project will ensure that we can cover these costs and provide Thembi with a safe and secure place to live as she seeks to rebuild her life.
In the past, Thembi was always one of the top pupils in her class at school. Since her ordeal began over two years ago, she has been forced to drop out of school and currently has no means to pay for her education. However, she is desparate to return to school. By legally transferring the house into Thembi's name, we can give her the long term security she needs as she starts to rebuild her life.


text:
Banjo are an easy slip-on style with a flat heel and a soft leather lining. They can be teamed with cigarette trousers and a blouse for the office or for more casual days with skinny jeans and jersey basics. Heel height: 2 cm
Thank you for visiting Gabor Banjo Suede Shoes, Black on shoppingfind.co.uk
We bring the products from many websites to one website for you to search, save and compare.


text:
Aam Aadmi Party (AAP) member of Parliament (MP) from Faridkot Sadhu Singh has been caught on a slippery pitch as one of his close aides and AAP's ad hoc committee member Sandeep Handa's pictures have been making rounds on social networking sites showing Handa assisting rebel Balkar Sidhu while filing nomination papers as Independent.
These pictures have been uploaded on social media by none other than the former Faridkot AAP convener Jivanjot Kaur. Earlier, she had also written a hard-hitting letter to Sadhu Singh to ask his student (Balkar) to withdraw nominations as Independent against the AAP official candidate Baljinder Kaur.
Sandeep Handa had no clear answer when HT asked him why he, being a party office-bearer, accompanied Balkar Sidhu while filing nomination papers despite the fact that the party had given ticket to Baljinder Kaur after rejecting Balkar's candidature.
Handa said, "We have been working to pacify Balkar Sidhu. Even Sadhu Singh has been making all the efforts. We are very much sure that Bakar will take back his nomination in the last hours."
Like Balkar, Handa is a close aide of Sadhu Singh who, along with Faridkot MP Bhagwant Mann , had pressurized the AAP high command to secure the party ticket for Balkar. AAP later took a U-turn in view of allegations of human trafficking surfaced against Balkar.
However, the incident has also exposed the internal divide in AAP and it is an open war on social networking sites.
"Jivanjot is an ex-convener of the party. She runs her own webpage. The party has nothing to do with it," said Handa, in his defence. However, he could not disown the allegations and his pictures with Balkar.
Besides, in a defensive mode, MP Sadhu Singh made little attempt to protect Handa and said that photos were needed to be verified before taking any disciplinary action against Sandeep Handa.
He said he had contacted Balkar Sidhu to take back his nomination, but still no there was no response from him.
"He can take the nomination back but nothing could be said with certainty," said Sadhu Singh.


text:
It's Sweet 16 time in the NCAA men's basketball tournament and luckily, there are still some excellent Cinderella teams to root for.
Unfortunately, in Thursday's match-ups, the underdogs are playing each other when No. 13-seed La Salle takes on No. 9-seed Wichita State. Whereas over in the East region, so far the seeds have gone completely chalk.
Here are the Thursday match-ups, check your local listings for details. All times Eastern.
Marquette vs. Miami, 7 p.m., CBS
Arizona vs. Ohio State, 7:30 p.m., TBS
Syracuse vs. Indiana, 9:30 p.m., CBS
La Salle vs. Wichita State, 10 p.m., TBS


text:
Notice: On March 31, it was announced that Statalist is moving from an email list to a forum. The old list will shut down on April 23, and its replacement, statalist.org is already up and running.
[Date Prev][Date Next][Thread Prev][Thread Next][Date Index][Thread Index]
st: robust poisson regression vs. glm with log link
"Dimitriy V. Masterov" <email@example.com>
Statalist <firstname.lastname@example.com>
st: robust poisson regression vs. glm with log link
Tue, 23 Aug 2011 14:03:25 -0400
William Gould has a new post on the NEC blog about how Poisson
regression with vce(robust) is a better alternative to log-linear
I can't seem to comment there, so I hope I can post my questions here
to get some insight. First, how does the robust Poisson model perform
relative to glm with a log link function? Are there ways to get the
elasticities from the poisson and/or glm coefficients?
* For searches and help try:
* http://www.stata.com/help.cgi?search
* http://www.stata.com/support/statalist/faq
* http://www.ats.ucla.edu/stat/stata/


text:
Mission Statement
The Wisconsin Economics Association (WEA) is a non-profit organization whose purposes are the advancement of economic knowledge and the economics profession. In general, the WEA seeks to establish and maintain a strong network among Wisconsin economists as well as economists across the Midwest.The WEA hosts an annual conference for members to exchange ideas, present research and foster collaboration.The conference is typically scheduled in late October or early November.
2017 WEA Conference November 17-18
2018 WEA Conference October 26-27
Click here for WEA conference information
The WEA is particularly interested in supporting:
• Undergraduate and graduate student research presentations
• Research into the teaching of economics at the college and university level
• Research examining topics of regional interest
Board Members:
President: Eric Jamelske, UW-Eau Claire, email@example.com
Vice-President: Laura Wind-Norton, Nicolet College, firstname.lastname@example.com
Treasurer: Matt Raunio, UW-Sheboygan, email@example.com
Presentation Coordinator: Eric Jamelske, UW-Eau Claire, firstname.lastname@example.com
Development Coordinator: Cory Wanek, Waukesha Technical College, firstname.lastname@example.com
Website Development: Eric Jamelske, UW-Eau Claire, email@example.com
Supporting Board Members:
Musa Ayar, UW-Baraboo/Sauk County, email@example.com
Jason Davis, UW-Stevens Point, email@example.com
Yunsun Huh, UW-Green Bay, email@example.com
Thomas Kemp, UW-Eau Claire, firstname.lastname@example.com
Sakib Mahmud, UW-Superior, firstname.lastname@example.com
John Stoll, UW-Green Bay, firstname.lastname@example.com
Andrew Weier, Saint Joseph's Hospital, email@example.com
Matthew Winden, UW-Whitewater, email@example.com
Student Board Members:
Elliot Charette, UW-Superior, firstname.lastname@example.com
Greg Sikowski, UW-Eau Claire, email@example.com
Helue Vazquez Valverde, UW-Eau Claire, firstname.lastname@example.com


text:
Judy: Amen, sister nurse, amen. I take it your nurses are not unionized
and therefore can't be forced to work overtime??? This has been the ONLY
good thing about continuing to work as a nurse at the large hospital I
work at...the protection offered by a good, solidly written contract!
Melody, IA (Z 5/4)
"The most beautiful thing we can experience is the mysterious."
--Albert Einstein
--- On Mon 08/09, Judy L Browning < email@example.com > wrote:
From: Judy L Browning [mailto: firstname.lastname@example.com]
To: email@example.com
Date: Mon, 9 Aug 2004 10:05:32 -0700
Subject: [CHAT] gainful employment/burnout
Well folks, in the last 3 days, my so called 8 hour shifts have
stretched to
9-11 hours with no time for a lunch break. 5 hours
overtime, or about an
extra day's pay for the 3 days. Not sure it's
worth it. They staff by
algorithm at this hospital rather than by
acuity. I fail to understand how
paying 2 or 3 nurses overtime is
cheaper than paying an extra assisitant. I
can afford to work only 6
days every 2 weeks, and can't afford to work more,
emotionally or
physically. A lot of nurses choose to take other, less
lucrative work
because of the killer stress involved.
Getting off my soap box,
thanks for letting me
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Monthly Archives: May 2011
There Is A Chance That I May Speak At TAM9!
TAM – The Amazing Meeting 9 will be in Vegas – July 14-17, 2011. Every year they put out a call for "papers". Anyone can propose a presentation. If they choose yours, you get 20 minutes to do a presentation … Continue reading
Posted in Personal Stories 3 Comments
Robert Ballard Explains Why Ocean Exploration Is A Good Investment – Colbert Video
Feb 10, 2009. Over 2 years old but it is really cool. The Colbert Report Tags: Colbert Report Full Episodes,Political Humor & Satire Blog,Video Archive
Posted in Science Comments Off on Robert Ballard Explains Why Ocean Exploration Is A Good Investment – Colbert Video
This Would Be A Good Graduation Prayer!
catholic Rabbits
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Hello Out There In Postapocalyptia
Post by Derrick ———————————————– Harold Camping's Family Radio has gotten a great deal of unwarranted attention (and a pile of money, strangely) from its epically-failed May 21, 2011 prediction of the Rapture. (He now says it was "spiritual" in nature … Continue reading
Posted in religion Tagged atheism, counterapologetics, Rapture 1 Comment
Creationism Banned From "free schools" In Britain
via NCSE "Free school bids from groups advocating creationism and intelligent design as scientific theories will not be approved, according to the first government guidance on the issue," reports the Times Education Supplement (May 20, 2011). The guidelines by which … Continue reading
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In a world full of misguided lies a shining light exists
Created for the only one who can wake me with a kiss
Raise me from the shadows, remove me from the pain
Shelter me from the barren cold, hide me from the rain
Eternal circumference that was made for you, are you really the one?
The bearer holds the destiny, as the Earth is to the Sun
Will many own the band before the bearer is revealed before my eyes?
Time may hold such answers as I cannot face no more lies
If she is the one in life, the one to wear the ring
Let the rainclouds lift this night and the Nightingale can sing
© Copyright 2017 deanfraserphillips. All rights reserved.
Status: Finished
Genre: Poetry
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Research in Computational Molecular Biology
Volume 3909 of the series Lecture Notes in Computer Science pp 231-245
Algorithms to Distinguish the Role of Gene-Conversion from Single-Crossover Recombination in the Derivation of SNP Sequences in Populations
- Yun S. SongAffiliated withDepartment of Computer Science, University of California
- , Zhihong DingAffiliated withDepartment of Computer Science, University of California
- , Dan GusfieldAffiliated withDepartment of Computer Science, University of California
- , Charles H. LangleyAffiliated withSection of Evolution and Ecology, University of California
- , Yufeng WuAffiliated withDepartment of Computer Science, University of California
* Final gross prices may vary according to local VAT.Get Access
Meiotic recombination is a fundamental biological event and one of the principal evolutionary forces responsible for shaping genetic variation within species. In addition to its fundamental role, recombination is central to several critical applied problems. The most important example is "association mapping" in populations, which is widely hoped to help find genes that influence genetic diseases [3, 4]. Hence, a great deal of recent attention has focused on problems of inferring the historical derivation of sequences in populations when both mutations and recombinations have occurred. In the algorithms literature, most of that recent work has been directed to single-crossover recombination. However, gene-conversion is an important, and more common, form of (two-crossover) recombination which has been much less investigated in the algorithms literature.
In this paper we explicitly incorporate gene-conversion into discrete methods to study historical recombination. We are concerned with algorithms for identifying and locating the extent of historical crossing-over and gene-conversion (along with single-nucleotide mutation), and problems of constructing full putative histories of those events. The novel technical issues concern the incorporation of gene-conversion into recently developed discrete methods [20, 26] that compute lower and upper-bound information on the amount of needed recombination without gene-conversion. We first examine the most natural extension of the lower bound methods from [20], showing that the extension can be computed efficiently, but that this extension can only yield weak lower bounds. We then develop additional ideas that lead to higher lower bounds, and show how to solve, via integer-linear programming, a more biologically realistic version of the lower bound problem. We also show how to compute effective upper bounds on the number of needed single-crossovers and gene-conversions, along with explicit networks showing a putative history of mutations, single-crossovers and gene-conversions.
We validate the significance of these methods by showing that they can be effectively used to distinguish simulation-derived sequences generated without gene-conversion from sequences that were generated with gene-conversion. We apply the methods to recently studied sequences of Arabidopsis thaliana, identifying many more regions in the sequences than were previously identified [22], where gene-conversion may have played a significant role. Demonstration software is available at www.cs. ucdavis.edu/~gusfield.
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- Title
- Algorithms to Distinguish the Role of Gene-Conversion from Single-Crossover Recombination in the Derivation of SNP Sequences in Populations
- Book Title
- Research in Computational Molecular Biology
- Book Subtitle
- 10th Annual International Conference, RECOMB 2006, Venice, Italy, April 2-5, 2006. Proceedings
- Pages
- pp 231-245
- Copyright
- 2006
- 10.1007/11732990_20
- Print ISBN
- 978-3-540-33295-4
- Online ISBN
- 978-3-540-33296-1
- Series Title
- Lecture Notes in Computer Science
- Series Volume
- 3909
- Series ISSN
- 0302-9743
- Publisher
- Springer Berlin Heidelberg
- Copyright Holder
- Springer-Verlag Berlin Heidelberg
- Additional Links
- Topics
- Industry Sectors
- eBook Packages
- Editors
- Alberto Apostolico (19)
- Concettina Guerra (20)
- Sorin Istrail (21)
- Pavel A. Pevzner (22)
- Michael Waterman (23)
- Editor Affiliations
- 19. Georgia Institute of Technology and Università di Padova
- 20. Topic Chairs
- 21. Center for Molecular Biology and Computer Sciecne Department, Brown University
- 22. University of California
- 23. Department of Molecular and Computational Biology, University of Southern California
- Authors
- Yun S. Song (24)
- Zhihong Ding (24)
- Dan Gusfield (24)
- Charles H. Langley (25)
- Yufeng Wu (24)
- Author Affiliations
- 24. Department of Computer Science, University of California, Davis, CA, 95616, USA
- 25. Section of Evolution and Ecology, University of California, Davis, CA, 95616, USA
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To view the rest of this content please follow the download PDF link above.


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The long-term goals of the proposed research are to elucidate the mechanisms that regulate dendrite morphogenesis in the mammalian brain. We recently discovered that the ubiquitin ligase Cdc20-anaphase promoting complex (Cdc20-APC) promotes the generation and elaboration of dendrites in postmitotic mammalian neurons. Genetic knockdown of Cdc20 by RNAi in cerebellar slices and in in vivo in the postnatal rat cerebellum revealed an essential function for Cdc20 in dendrite growth and arborization. Remarkably, Cdc20 is concentrated at the centrosome in neurons, and the centrosomal localization is required for neuronal Cdc20- APC to drive dendrite development. These findings have raised several fundamental questions on how the novel function of Cdc20-APC is regulated in neurons and how Cdc20-APC orchestrates dendrite development. To address these questions, we propose to identify the key domains and posttranslational modifications within Cdc20 that contribute to Cdc20-APC function in dendrite morphogenesis. We will also identify the substrates of neuronal Cdc20-APC that control dendrite growth and elaboration. Finally, based on preliminary evidence, we will characterize the developmental role of a Cdc20-APC in dendrite remodeling and patterning in the cerebellar cortex. The proposed research represents an important set of experiments that will address a major gap in our understanding of the cell-intrinsic mechanisms that underlie neuronal morphogenesis and connectivity. In addition, since abnormalities of dendrite morphology are thought to contribute to the pathogenesis of diverse neurological and psychiatric disorders, including neurodegenerative diseases and mental retardation, the proposed research should provide the foundation for a better understanding of these disorders.
Dendrites are the critical receptive limb of neurons and accordingly the morphology of dendrites is critical for the normal function of neuronal circuits in the brain. We propose to identify the key mechanisms and principles that govern dendrite development. Abnormalities of dendrite morphology may contribute to the pathogenesis of diverse neurological and psychiatric disorders as well as adult neurodegenerative disorders. Therefore, understanding how dendrites are form and shaped is not only essential for a better understanding of brain development but also for insights into a whole host of brain disorders.
|Mar, Fernando M; Bonni, Azad; Sousa, Mónica M (2014) Cell intrinsic control of axon regeneration. EMBO Rep 15:254-63
|Puram, Sidharth V; Kim, Albert H; Park, Hye-Yeon et al. (2013) The ubiquitin receptor S5a/Rpn10 links centrosomal proteasomes with dendrite development in the mammalian brain. Cell Rep 4:19-30
|Ikeuchi, Yoshiho; de la Torre-Ubieta, Luis; Matsuda, Takahiko et al. (2013) The XLID protein PQBP1 and the GTPase Dynamin 2 define a signaling link that orchestrates ciliary morphogenesis in postmitotic neurons. Cell Rep 4:879-89
|Yamada, Tomoko; Yang, Yue; Bonni, Azad (2013) Spatial organization of ubiquitin ligase pathways orchestrates neuronal connectivity. Trends Neurosci 36:218-26
|Huynh, Mai Anh; Ikeuchi, Yoshiho; Netherton, Stuart et al. (2011) An isoform-specific SnoN1-FOXO1 repressor complex controls neuronal morphogenesis and positioning in the mammalian brain. Neuron 69:930-44
|Puram, Sidharth V; Kim, Albert H; Ikeuchi, Yoshiho et al. (2011) A CaMKII* signaling pathway at the centrosome regulates dendrite patterning in the brain. Nat Neurosci 14:973-83
|Puram, Sidharth V; Bonni, Azad (2011) Novel functions for the anaphase-promoting complex in neurobiology. Semin Cell Dev Biol 22:586-94
|Puram, Sidharth V; Riccio, Antonio; Koirala, Samir et al. (2011) A TRPC5-regulated calcium signaling pathway controls dendrite patterning in the mammalian brain. Genes Dev 25:2659-73
|Litterman, Nadia; Ikeuchi, Yoshiho; Gallardo, Gilbert et al. (2011) An OBSL1-Cul7Fbxw8 ubiquitin ligase signaling mechanism regulates Golgi morphology and dendrite patterning. PLoS Biol 9:e1001060
|Pot, I; Ikeuchi, Y; Bonni, A et al. (2010) SnoN: bridging neurobiology and cancer biology. Curr Mol Med 10:667-73
Showing the most recent 10 out of 27 publications


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Thomas Newman (born October 20, 1955) is an American film score composer and a member of a family who established a film-scoring dynasty in Hollywood.Amazon.com Will it become another rich Newman family tradition? Picking up the baton his cousin Randy carried so skillfully on Disney/Pixar's four previous pioneering ...3/21/2012 · A quick look at the amazing cast of The Best Exotic Marigold Hotel lets me know that this is a film I need to see -- Maggie Smith, Judi Dench, Bill Nighy ...Visit Amazon.com's Thomas Newman Store to shop for Thomas Newman albums (CD, MP3, Vinyl), concert tickets, and other Thomas Newman-related products (DVDs, …Road to Perdition by Thomas Newman - Original Soundtrack Review at Tracksounds.Erin Brockovich by Thomas Newman - Original Soundtrack review at Tracksounds.Skyfall: Original Motion Picture Soundtrack is the soundtrack album to the 23rd James Bond film of the same name. Released by Sony Classical on October 29, 2012 …8/17/2010 · Complete MP3 file (32min 38sec - 74MB): http://ul.to/a7d0gbek Perfect meditation. Created using the Paulstretch effect on Audacity, a great free open ...Thomas Newman On The Skyfall Soundtrack The Skyfall composer discusses some of the key tracks on the Bond soundtrackWatch the video or listen to Thomas Newman – Any Other Name for free. Any Other Name appears on the album American Beauty. Thomas Newman (born October 20, …
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Jeanette MacDonald Biography (Wikipedia)
Jeanette Anna MacDonald (June 18, 1903 – January 14, 1965) was an American singer and actress best remembered for her musical films of the 1930s with Maurice Chevalier (The Love Parade, Love Me Tonight, The Merry Widow and One Hour With You) and Nelson Eddy Naughty Marietta, Rose-Marie, and Maytime). During the 1930s and 1940s she starred in 29 feature films, four nominated for Best Picture Oscars (The Love Parade, One Hour with You, Naughty Marietta and San Francisco), and recorded extensively, earning three gold records. She later appeared in opera, concerts, radio, and television. MacDonald was one of the most influential sopranos of the 20th century, introducing opera to movie-going audiences and inspiring a generation of singers.
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The Guardian's coverage of last week's sale of the two Independent titles to Alexander Lebedev was characteristically charitable. By that I mean characteristically uncharitable. The paper highlighted Mr Lebedev's past as a former KGB agent, and suggested that the sale of the papers for one pound to such a man was somehow a betrayal of their original values.
Perhaps as one of The Independent's three journalistic founders in 1986 I might be allowed a word on that last point. The dream of a profitable, non-partisan newspaper free of proprietorial control has been dead for many years. To be precise, it died when Mirror Group Newspapers became dominant shareholders in the titles in 1995. We could argue whether, if mistakes had not been made, the dream could have been sustained, but the fact is that it collapsed long ago.
And, as it happens, the Independent titles have been fortunate with proprietors. I exclude Mirror Group, which never quite got the point of The Independent, but its partner, Dublin-based Independent News and Media (INM), certainly did, and was able to call the shots after gaining control in 1998. Naturally errors were made – costs could have been cut earlier; and I have always thought the titles should have maintained a wider political appeal – but INM have been good proprietors, and this paper and its Sunday sister owe the company's former controlling shareholder and chief executive, Sir Tony O'Reilly, a great debt.
As for Mr Lebedev, his one-time links to the KGB are beside the point. They belong to another world, as does the launch of The Independent. In the world we inhabit he is an enormously rich man who wants to run good newspapers. He is part owner of one of the very few independent titles in Russia, and last year acquired the London Evening Standard. His record as a newspaper publisher suggests he believes in journalism and freedom and democracy, and I would have thought that the original values of this newspaper were as safe in his hands as in anyone's.
So our friends at The Guardian need not fret on that score. My worries are quite different. In its twenty-three-and-a-half year life, The Independent has only made a profit for one, possibly two, years. Its habit of losing money does not make it unique. I doubt The Times has been profitable during a single year since Rupert Murdoch bought it in 1981, and figures released last week suggest that it lost at least £70m, possibly as much as £85m, in the 12 months to June 2009. The Guardian's annual losses are running at about £30m. The Independent is said to have lost £12m last year.
Of course, to read the lordly put-downs of this newspaper in The Guardian or The Times, you would think its finances were in some freakish category of their own. Journalists on those titles apparently believe that the Scott Trust and Rupert Murdoch respectively will bankroll them for ever. I wouldn't be so sure. (For the sake of all newspapers, I am praying that Mr Murdoch's plans, announced last week, to erect an online paywall around The Times and The Sunday Times will succeed, though I have my doubts.) Those who cherish The Independent would be wise to take a more hard-headed approach to its finances.
How easy it would be to say that, as Mr Lebedev is a billionaire, he can keep The Independent and its sibling going for as long as he likes out of petty cash. In the bleak times in which we live, where most quality newspapers are losing money and none can be certain of a long-term future, it is no longer safe to rely on a munificent sugar daddy, as The Times, The Guardian and (let's be honest) The Independent have done for too long.
I don't think Mr Lebedev is a sugar daddy, and I hope he has not acquired The Independent as a trophy to stick on his mantelpiece. I believe that this newspaper will only be secure if it can break even. Surely it is obvious that the present model is never going to be commercially viable. Left alone, the paper will continue to wither, as The Times and The Guardian are continuing to wither, each rather magnificent in its way, but each dangerously, and potentially fatally, far from profitability.
Here The Independent has one advantage, which is that, unlike its rivals, it has already substantially reduced its costs, though there may well be more work to be done. Its disadvantage is to have fewer sales, and therefore more ground to make up. Marketing, vital though it is, cannot achieve this alone. There has been talk of making the paper free in some metropolitan centres and of cutting its cover price as a promotional tool. Both are exciting options, conveying the realisation that things cannot go on as they are. No doubt other radical ideas are necessary.
Will The Independent be around in 10 or 20 years' time? Only if it acquires the habit of not losing money. I would say exactly the same about The Guardian and The Times. Mr Lebedev and his son Evgeny, who will be chairman of the new company owning the Independent titles, come with fresh ideas and open minds, though they have limited experience of British newspapers, and may be forgiven if they feel they have too many people bellowing advice in their ears. The future of The Independent and The Independent on Sunday lies in their hands.
Mr Cameron's coarse new best friend may become a liability
Nick Griffin, the BNP leader, does not obviously look like a thug. It is the shaven-haired heavies surrounding him who make you queasy. I wonder whether people are having similar thoughts about David Cameron on account of his new best friend, The Sun.
Like some over-zealous sidekick, the paper feels obliged not only to cheer its new hero at every opportunity but also to put the boot into his political adversaries whenever possible. Its post-Budget headline last Thursday did this with such crudity that even the Tory leader must have winced: "Darling just screwed more people than JT, Ashley, Mark Owen and Tiger Woods".
This from a paper once proud of its front page headlines such as "Gotcha" and "Will the last person to leave Britain please turn off the light?" and "Freddie Starr ate my hamster". The Sun's editorials, which only a few months ago defended Gordon Brown, now describe him and New Labour in vituperative terms. If I were a floating voter who read the paper, I might be put off the Tories by such coarse and clunking propaganda.
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When I run access-fannkuch.js with TMFLAGS=profile, I learn that the hottest block, 000046, which accounts for 33% of block entries, ends with this delightful code:
ld16 = ld sp[-152]
$stack2 = i2f ld16
sti sp[-152] = ld16
ld17 = ld sp[-128]
$stack5 = i2f ld17
sti sp[-128] = ld17
ld18 = ld sp[-88]
$stack10 = i2f ld18
sti sp[-88] = ld18
ld19 = ld sp[-80]
$stack11 = i2f ld19
sti sp[-80] = ld19
sti sp[-72] = addxov1
ld20 = ld sp[-64]
$stack13 = i2f ld20
sti sp[-64] = ld20
ld21 = ld sp[-48]
$stack15 = i2f ld21
sti sp[-48] = ld21
sti sp[-32] = ld15
ld22 = ld sp[-8]
$stack20 = i2f ld22
sti sp[-8] = ld22
j -> label1
At the end of the pipeline it looks like this:
ld16 = ld sp[-152]
sti sp[-152] = ld16
ld17 = ld sp[-128]
sti sp[-128] = ld17
ld18 = ld sp[-88]
sti sp[-88] = ld18
ld19 = ld sp[-80]
sti sp[-80] = ld19
sti sp[-72] = addxov1
ld20 = ld sp[-64]
sti sp[-64] = ld20
ld21 = ld sp[-48]
sti sp[-48] = ld21
sti sp[-32] = ld15
ld22 = ld sp[-8]
sti sp[-8] = ld22
j -> label1
The next few hottest blocks in fannkuch.js end with very similar sequences.
It'd be nice to avoid these redundant loads and stores. If I had to guess I'd blame ImportBoxedStackSlotVisitor, but I don't really know. Some of those stack slots aren't even touched by the rest of the block.
ImportBoxedStackSlotVisitor shouldn't generate all that (I hope not!)
What line(s) of code did this correspond to in fannkuch? Are we importing these slots in one huge batch (like at a tree call site)?
(In reply to comment #1)
> ImportBoxedStackSlotVisitor shouldn't generate all that (I hope not!)
I could be totally wrong about blaming it, I don't understand that stuff much at all.
> What line(s) of code did this correspond to in fannkuch?
The five hottest blocks all have code like that. They correspond to lines 34, 27, 32, 50, 46. I suspect just about every loop will look the same.
> Are we importing these
> slots in one huge batch (like at a tree call site)?
No idea about that. If you want to see the code, run something like this:
TMFLAGS=minimal,recorder,fragprofile debug32/js -j $SS/access-fannkuch.js
The fragprofile stuff is at the bottom, use the FragID markers to navigate.
Created attachment 453014 [details] [diff] [review]
Holy crap! I was going over old bugs today and decided to look at this one again. The culprit is SlotMap::adjustType(). Turns out we load from a stack/global slot, do a d2i, and then immediately store back into it. It's got something to do with type stability that I don't fully understand.
But if the loaded value itself comes from an i2d/ui2d, that cancels out the d2i and so we end up storing back the same value.
The attached patch simply looks for this case and avoids the store. When this happens the load becomes dead and it's removed by Nanojit's DCE.
These stupid instructions turn out to be really common, almost every progrma in SS/V8 is affected. On 32-bit Mac I see a 2.3% speedup for all of SunSpider, and 4.5% if you exclude the regexp and string tests. V8 gets about 3%. Instruction count improvements for all of SS are as follows:
total 2,356,164,230 2,317,524,894 1.017x better
on-trace 616,577,164 579,917,401 1.063x better
Not bad for a 10 line patch :)
Full Cachegrind results:
instructions executed (nb: "on-trace" may overestimate slightly)
total 127,562,453 125,316,011 1.018x better
on-trace 25,355,526 23,185,247 1.094x better
total 66,700,088 63,283,207 1.054x better
on-trace 25,516,652 22,144,236 1.152x better
total 142,218,300 141,482,814 1.005x better
on-trace 25,694,660 25,535,120 1.006x better
total 78,298,453 78,064,529 1.003x better
on-trace 18,934,574 18,709,337 1.012x better
total 192,025,263 180,772,877 1.062x better
on-trace 115,868,184 105,072,844 1.103x better
total 84,699,885 84,402,173 1.004x better
on-trace 31,013,260 30,755,784 1.008x better
total 61,157,732 58,316,554 1.049x better
on-trace 29,270,213 26,450,687 1.107x better
total 16,183,512 15,795,755 1.025x better
on-trace 3,372,932 2,988,877 1.128x better
total 47,594,297 44,090,318 1.079x better
on-trace 34,580,446 31,085,902 1.112x better
total 24,551,044 23,349,502 1.051x better
on-trace 12,016,854 10,816,828 1.111x better
total 90,488,512 84,978,832 1.065x better
on-trace 47,729,371 42,249,979 1.130x better
total 44,322,686 43,464,923 1.020x better
on-trace 28,337,181 27,505,221 1.030x better
total 49,130,970 48,918,426 1.004x better
on-trace 5,808,596 5,637,685 1.030x better
total 34,054,482 33,187,715 1.026x better
on-trace 7,853,087 7,251,962 1.083x better
total 135,816,270 135,603,460 1.002x better
on-trace 11,562,104 11,351,070 1.019x better
total 105,342,104 105,244,850 1.001x better
on-trace 11,628,622 11,608,362 1.002x better
total 55,781,955 55,424,599 1.006x better
on-trace 30,688,747 30,338,640 1.012x better
total 38,832,084 38,547,468 1.007x better
on-trace 6,560,110 6,288,303 1.043x better
total 30,343,887 29,802,219 1.018x better
on-trace 11,769,512 11,276,109 1.044x better
total 115,080,787 115,080,743 --
on-trace 75,041,535 75,041,535 --
total 54,989,436 54,851,994 1.003x better
on-trace 8,277,642 8,154,541 1.015x better
total 132,064,626 129,052,269 1.023x better
on-trace 29,493,488 26,545,259 1.111x better
total 272,222,837 272,132,591 --
on-trace 6,673,511 6,592,119 1.012x better
total 273,432,506 273,242,758 1.001x better
on-trace 5,680,936 5,614,638 1.012x better
total 83,270,061 83,118,307 1.002x better
on-trace 7,849,421 7,717,116 1.017x better
total 2,356,164,230 2,317,524,894 1.017x better
on-trace 616,577,164 579,917,401 1.063x better
Comment on attachment 453014 [details] [diff] [review]
njn++. Nice find.
Created attachment 453017 [details]
SS results
I love that the biggest speedup (1.27x) is for bitwise-and :)
It's worth pointing out that this doesn't just remove the obvious load/store pairs like those in comment 0. There are lots of cases where just a store is removed. For example, here's the code for bitwise-and.js; the lines marked with '*' are those that are removed:
ebx = parami 0 ebx
esi = parami 1 esi
edi = parami 2 edi
state = parami 0 ecx
sp = ldi.o state[8]
cx = ldi.o state[0]
eos = ldi.o state[12]
ldi3 = ldi.csro cx[0]
immi3 = immi 0
eqi1 = eqi ldi3, immi3/*0*/
xf2: xf eqi1 -> pc=...... imacpc=(nil) sp+0 rp+0 (GuardID=001)
ldi2 = ldi.o eos[1376]
ldi1 = ldi.o eos[1368]
andi1 = andi ldi2, ldi1
sti.o eos[1376] = andi1
immi2 = immi 1
addxovi1 = addxovi ldi1, immi2/*1*/ -> pc=...... imacpc=(nil) sp+0 rp+0 (GuardID=002)
sti.o eos[1368] = addxovi1
sti.s sp[0] = addxovi1
immi1 = immi 600000
sti.s sp[8] = immi1/*600000*/
lti1 = lti addxovi1, immi1/*600000*/
xf1: xf lti1 -> pc=...... imacpc=(nil) sp+16 rp+0 (GuardID=003)
* sti.o eos[1376] = andi1
* sti.o eos[1368] = addxovi1
j -> label1
livei state
x1: x -> pc=...... imacpc=(nil) sp+0 rp+0 (GuardID=004)
They just duplicate stores from earlier in the block.
TM wins still available is good news. We need 'em, along with JM.
Awesome find.
The only way TypeCheck_Promote is returned is if the slot has a trivial conversion, i.e. isPromoteInt would return true. This patch works because any time we sink a promoteInt back, we d2i() it first. Therefore, do we need the d2i() call at all? Removing the whole |if| branch passes trace-tests for me.
Created attachment 453259 [details] [diff] [review]
alternative patch
This patch takes advantage of dvander's observation. It's better because it catches some cases the first patch didn't -- when the instruction is an integral immediate double.
One thing I don't like is that it can result in different LIR being generated for debug and opt builds, because of the debug-only get() call. (The final LIR will be the same, however, because the extra LIR instructions generated in debug builds are dead.) The debug-only call to get() can also change other state, eg. that of the oracle.
I could just remove the assertion for the TypeCheck_Promote case, but I don't want to do that. Can anyone see how to retain it without generating LIR and changing state?
Comment on attachment 453259 [details] [diff] [review]
alternative patch
urgh, yeah, that's kind of nasty. Maybe getFromTracker, which won't cause an import? It can return NULL.
After discussion with dvander on IRC, the pushed version ended up calling getFromTracker() and not doing the check when it returns NULL.


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Blog Posts in Category: Perfectionism
June 27, 2014
College students (and all of us) are burdened by the idea that we have to succeed in all areas of our lives to be as well balanced as we can, but when does the idea of being perfect go too far? At times, there is a lot of pressure to get the best grades possible on our finals. There are many people that struggle with perfectionism, whether it is realized or not. Perfectionism is described as the belief that making mistakes us unacceptable, and everything must be error-free. Perfectionists... Read More
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How to Best Understand Nutrition Fact Labels and Build a Healthy Diet If you want to start eating... Read more
Do You Have Questions About Following a Plant-Based Diet? Read More to Find Answers! About 7.3... Read more
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text:
And so, as Tiny Tim observed, "God Bless us!! Everyone!!''
A Christmas Carol - Charles Dickens (1843)
nothing right now..
one of my daughters, who turned 21 this past June, had been on an anti seizure medication for about 6 years. before she was on it, she had had 3 gran mal seizures in her life, spaced many years apart. the first one at 14 months, the second at 9 years, and the third at 15 years. since she turned 21, she was no longer eligible for the insurance she was on, so she had to go off the med and has not taken it since the end of june. this past summer, when we were visiting my sister, her family , and my mother up north, my daughter, decided to stay and live with them and got a job (her first). well, today, my sister called me to say that my daughter had had a seizure. she took her to the ER, even though she knew there was basically nothing they could do for her, but my daughter wanted to go. they ran some tests, that were all negative (they almost always are, unless a seizure is occurring at the time) but they gave her a prescription, which is great except how is she going to fill it without money or insurance? she doesn't earn much and my sister can't afford it. but, hopefully something will work out because she really needs the medication. she had the seizure around 2 this afternoon and by midnight, she still was not feeling right. it hurts her to eat or to walk.. she felt so disoriented earlier; it scared her.
The horrid weather...
Merry Christmas to all...


text:
Fountain Valley brings 'Frankenstein' to life
Thunder booms and lightning strikes. As in an old-fashioned black-and-white movie, the words flash across the screen, emblazoned against a creepy castle – "Young Frankenstein." But what starts as creepy and dark becomes vibrant and colorful in Fountain Valley's musical production of Mel Brooks' classic comedy.
In a little Transylvanian town, trouble brews upon Victor Frankenstein's death. It is then that grandson Frederick Frankenstein, or "Frank-in-steen," as he would say, comes to inherit the estate. After arriving, Frederick decides to re-create his grandfather's famous monster with the help of a crazy cast of characters.
Jeremy Flores plays the awkward, fidgety Frederick. Forever in his grandfather's shadow, shown in the song "The Brain," he vainly tries to prove his sanity. When frustrated at his experiment's lack of results, he flies into sudden comedic rages, showing the unpredictability of his character.
His decision to "Join the Family Business" is attributable to his faithful companion Igor, played by Nikki Tran. Like a puppy, Igor follows Fredrick everywhere, hunched over but able to spring into the air at a moment's notice.
Flores' and Tran's contrasting personalities and comedic timing shine brightest in "Together Again"; Tran bounces in exuberance, and Flores, though less sure at first, soon joins in the hilarity.
Also helping the young doctor is Inga, a beautiful local girl, played by Miranda Lennert. Sweet and trusting, she comforts Frederick when things go wrong. Even with the innuendos her character brings, Lennert never loses her innocence. In such songs as "Roll in the Hay," she swings her legs like a child and always has a smile on her face.
The ensemble maintains and builds energy, culminating in such songs as "Transylvania Mania" and "Puttin' on the Ritz." Although the singing is pitchy at times, overcoming that are the zany accents and over-the-top acting.
The sets by Julie Brashear, Ronald Daughton, Sam Maytubby and Danthi Tran add a creepy, foreboding atmosphere. Most notable is the platform lift carrying the doctor and the monster to heaven. Makeup and hair by Rebecca Turner and Miranda Lennert make each character unique, but especially the monster, who is humanly creepy.
With a reminder that what's on the inside is what counts, Fountain Valley puts the humor back in horror!
Claire Pukszta is a junior
at Northwood High School in Irvine.
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text:
DPBRN learned several lessons regarding its administrative structure in its early years;several aspects evolved accordingly. For example, although our PSC was the main decision-making body, we soon realized that we needed a Regional Directors Committee (RDC) to decide how best to implement those decisions. We next learned that the RDC could easily get its agenda bogged down by discussing details of particular studies, so next we formed study implementation groups, whose only agenda item was to discuss a single study. However, we next learned that this same team really needed to shepherd the study in each phase, from study design, to pilot testing, to field phase management, to data analysis and manuscript preparation. Thus we formed Study Teams for each study (led by the Study PI). Weekly meetings between the National Network Director group and the Data Coordinating Center group fostered communication between these two groups, adjusted priorities weekly, and established clarity about who was supposed to do what and when. We later realized that our Regional Coordinators (research assistants) needed to discuss agenda items not specific to a particular study, so we began Regional Coordinator meetings. We also learned that we needed a formal document to guide administration of publications and presentations, completing in 2006 the DPBRN publications policy [22], which in 2009 served as the template for the CONDOR three-network policy [23]. Coincident with all this we saw the communication value of taking minutes at each meeting, with a focus on recording Decisions, assigning Action Items with deadlines, and holding persons accountable for those items. Although this amounted to a significant number of committees, it improved our effectiveness substantially. Because the network must have many 'balls in the air'at the same time to maximize its productivity, we believe that this evolution in administrative structure fostered our productivity in the 2005-2012 cycle. Therefore, we propose the same administrative structure for NDPBRN, depicted in the graphic below. The best structure is the one that leads to the best function and performance. We believe that structure is best compared across networks not by comparing assertions about structure or planned collaborations, but by using objective measures of output (i.e., the ones delineated in Section B.I., p. 222).
|Kakudate, Naoki; Sumida, Futoshi; Matsumoto, Yuki et al. (2015) Dentists' decisions to conduct caries risk assessment in a Dental Practice-Based Research Network. Community Dent Oral Epidemiol 43:128-34
|Gordan, Valeria V; National Dental PBRN Collaborative Group (2014) Translating research into everyday clinical practice: lessons learned from a USA national dental practice-based research network. Tex Dent J 131:590-9
|Fellows, Jeffrey L; Gordan, Valeria V; Gilbert, Gregg H et al. (2014) Dentist and practice characteristics associated with restorative treatment of enamel caries in permanent teeth: multiple-regression modeling of observational clinical data from the National Dental PBRN. Am J Dent 27:91-9
|Ray, Midge N; Funkhouser, Ellen; Williams, Jessica H et al. (2014) Smoking-cessation e-referrals: a national dental practice-based research network randomized controlled trial. Am J Prev Med 46:158-65
|Norton, Wynne E; Funkhouser, Ellen; Makhija, Sonia K et al. (2014) Concordance between clinical practice and published evidence: findings from The National Dental Practice-Based Research Network. J Am Dent Assoc 145:22-31
|Riley 3rd, Joseph L; Gordan, Valeria V; Hudak-Boss, Susan E et al. (2014) Concordance between patient satisfaction and the dentist's view: findings from The National Dental Practice-Based Research Network. J Am Dent Assoc 145:355-62
|Makhija, Sonia K; Gilbert, Gregg H; Funkhouser, Ellen et al. (2014) Twenty-month follow-up of occlusal caries lesions deemed questionable at baseline: findings from the National Dental Practice-Based Research Network. J Am Dent Assoc 145:1112-8
|Makhija, S K; Gilbert, G H; Funkhouser, E et al. (2014) Characteristics, detection methods and treatment of questionable occlusal carious lesions: findings from the national dental practice-based research network. Caries Res 48:200-7
|Gordan, Valeria V; Riley 3rd, Joseph; Geraldeli, Saulo et al. (2014) The decision to repair or replace a defective restoration is affected by who placed the original restoration: findings from the National Dental PBRN. J Dent 42:1528-34
|Law, Alan S; Nixdorf, Donald R; Rabinowitz, Ira et al. (2014) Root canal therapy reduces multiple dimensions of pain: a national dental practice-based research network study. J Endod 40:1738-45
Showing the most recent 10 out of 28 publications


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Few fighters in mixed martial arts history have captured the imagination quite like UFC Hall of Famer 'Baby' Jay Dee Penn. A supremely talented "Prodigy" who truly sought out the very best competitio watch video >>
MMA H.E.A.T.'s Karyn Bryant talks with UFC legend BJ Penn about his upcoming fight with Rory MacDonald, set to take place at the UFC on FOX card on December 8th, 2012, in Seattle, WA. BJ tells us why watch video >>
MMA H.E.A.T.'s Karyn Bryant talks with UFC welterweight Rory MacDonald and hears his thoughts on his upcoming fight with BJ Penn, set to take place at the UFC on FOX card on December 8th, 2012, in Se watch video >>
BJ Penn will take on Rory MacDonald at UFC 152 in September in Toronto, Canada. It will likely be Penn's last fight in mixed martial arts, and a fight that can possibly catapult MacDonald into supers watch video >>
In mixed martial arts (MMA) news, Nate Diaz is trying to get a boxing license in Nevada, BJ Penn's future is in doubt after being badly defeated at UFC Fight Night 103 by Yair Rodriguez, the UFC 209 watch video >>
Following UFC on FOX 4, Dana White reveals that Rory MacDonald has been removed from his UFC 152 fight with BJ Penn, VADA testing and much more. Subscribe to our channel for more MMA videos! Click h watch video >>
MMA H.E.A.T. brings you this excerpt from UFC President Dana White's media scrum where he discusses VADA testing and announces Rory MacDonald and BJ Penn fight won't happen.Be sure to visit http://ww watch video >>
The legend BJ Penn takes on rising star Rory Macdonald on September 22, 2012 in at Air Canada Centre in Toronto, Canada, in what should be a amazing fight. watch video >>
UFC 152 Rory MacDonald vs BJ Penn In Depth Preview winner Condit vs GSP? watch video >>
MMA community reactions/reacts to Yair Rodriguez's TKO win over UFC Hall of Famer BJ Penn at UFC Fight Night 103 (UFC Phoenix) watch video >>
BJ Penn made his return to the Octagon against Yair Rodriguez. Check out the best moments. watch video >>
UFC Hall of Famer BJ Penn's long-awaited return to the Octagon will headline UFC Fight Night tonight, as "The Prodigy" faces Mexican phenom Yair Rodriguez in a five-round featherweight bout at Talkin watch video >>
BJ Penn vs Matt Serra
UFC 39 - The Warriors Return watch video >>


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|Message view
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|DO NOT REPLY [Bug 47645] httpd-2.2.12 often hangs for hours
|Mon, 10 Aug 2009 14:44:59 GMT
https://issues.apache.org/bugzilla/show_bug.cgi?id=47645 --- Comment #9 from HWS <email@example.com> 2009-08-10 07:44:54 PDT --- >You will likely be able to work around the problem by selecting a different >poll implementation. For testing, I compiled two new variants of libapr-1.so.0.3.7. First, I removed the line "#define HAVE_PORT_CREATE 1" from srclib/apr/include/arch/unix/apr_private.h, causing poll() instead of port_create() to be used (I verified that no reference to port_create() existed any more in the library). With this library, no hangs happened in 3,5 days. Second, I used port_create() but removed the two occurences of fcntl(fd, F_SETFD, flags) from srclib/apr/poll/unix/port.c, making it act as in httpd-2.2.11. But in spite of this, there soon were hangs again. Thus, NOT using port_create() seems to be a workaround. But still, I am not content with this, because 2.2.11 also used port_create() without ANY difficulties! (This is why I also tested the effect of F_SETFD in poll.c, which was new since 2.2.11. But there is F_SETFD in many other places, too.) The actual reason of the hanging is, IMHO, still unknown (some subtle, machine-dependent timing problem?). -- Configure bugmail: https://issues.apache.org/bugzilla/userprefs.cgi?tab=email ------- You are receiving this mail because: ------- You are the assignee for the bug. --------------------------------------------------------------------- To unsubscribe, e-mail: email@example.com For additional commands, e-mail: firstname.lastname@example.com
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text:
VICKSBURG — Eighteen North Vicksburg homeowners who suffered damage from the Mississippi River flooding this spring have signed up for the city's buyout program. The Vicksburg Post reports the voluntary buyout will be conducted in two phases. The first involves homes in the flood plain known as the city's 1 percent area and were determined by city building inspectors to ...Read More »
Tag Archives: homeowners
Flood victims to be offered buy-out program
VICKSBURG — Vicksburg officials will hold a forum on Sept. 1 at the Vicksburg Auditorium for homeowners in the areas hit by the 2011 flood who are interested in participating in a voluntary home buyout program. The Vicksburg Post reports that the city will apply for funding through the Federal Emergency Management Agency. The Mississippi River crested at 57.1 feet ...Read More »
A look at the pros and cons of home associations
Mr. and Mrs. Binder do not want to renew their homeowners' association dues, but they will be legally forced to if they do not pay up. Mr. and Mrs. Washington on the other hand are not going to renew their homeowners' association dues this year, but nothing will happen to them. Why the difference? The Binders live in a development ...Read More »
State's foreclosure actions up and down
ACROSS MISSISSIPPI — Home foreclosure actions in Mississippi rose in July from the previous month, but were down from a year ago, according to a national foreclosure tracking firm. Irvine, Calif.-based RealtyTrac said 359 housing unit were targeted for some sort of foreclosure action last month — and all of those homeowners were at the end of the line. Lenders ...Read More »
FEMA extends NFIP deadline for flood victims
WEST MISSISSIPPI — Mississippi flood policyholders insured through the National Flood Insurance Program and affected by the April and May flooding of the Mississippi River and its tributaries have been granted a 30-day extension to the deadline for filing a proof of loss statement with their insurer. National Flood Insurance Program policyholders are given 60 days from the date of ...Read More »
MHC launches Home Saver program for jobless homeowners
JACKSON — The Mississippi Home Corporation (MHC) has unveiled its Home Saver program to help unemployed Mississippians bring their mortgages current and make monthly mortgage payments for up to 12 months while they look for work. The program's Education Option assists homeowners for up to 12 additional months if they enroll in a certificate or degree-seeking program to improve their ...Read More »
Chaney issues moratorium on policy cancellations/non-renewals
JACKSON — To assist residents as they struggle to recover from last week's devastating storms, Commissioner of Insurance Mike Chaney has issued a bulletin to insurance carriers placing a 60-day moratorium on the cancellation/non-renewal of certain policies. The moratorium applies to commercial property, homeowners, dwelling fire and commercial and personal automobile insurance policies. The moratorium extension is not automatic. To ...Read More »
Cut loose by Allstate, homeowners likely to find coverage elsewhere
With hurricane season's official start less than a month away, 5,000 Mississippi homeowners face the prospect of losing their Allstate home insurance coverage. But state polices adopted after Katrina in 2005 should go a long way toward ensuring the homeowners can find policies elsewhere, say Professor Larry Cox of the University of Mississippi and Matt Wulf of the Reinsurance Association ...Read More »
FEMA approves wind-retrofitting grant for Coast homeowners
MISSISSIPPI GULF COAST — U.S. Senators Thad Cochran (R-Miss.) and Roger Wicker (R-Miss.) announced the approval of a $22-million grant to assist eligible homeowners in Mississippi's coastal counties in retrofitting their homes to withstand destructive winds. The Federal Emergency Management Agency (FEMA) has approved the Mississippi Emergency Management Agency's request for federal funding to support a Wind Retrofit Coastal Initiative ...Read More »
Allstate asking for increase in homeowner insurance rates
ACROSS MISSISSIPPI — Mississippi Insurance Commissioner Mike Chaney says Allstate Property and Casualty Co. will increase homeowner insurance rates 19.4 percent in Mississippi. Chaney told The Sun Herald newspaper that Allstate was threatening to drop 18,000 policyholders unless he allowed a rate hike of at least 44 percent. He said he "worked diligently to negotiate the requested rate down to ...Read More »


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text: A year and a half later, I haven't heard how my bone-marrow recipient is doing. Delete Blood Cancer hasn't come back to me asking for another bone marrow donation, so I'm hoping that's a good thing and that she's doing great. But if they do call me back, whether it's for her or someone else, I'd do it again in a heartbeat.


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JOIN the world's largest horse forum! Chat and learn from other experts about horse training, breeding, health, showing, riding, contests and use our free horse classifieds. Register Here
26 yr old mare with swollen teats
Discussion in 'Horse Health' started by BettaBlossoms, Apr 20, 2008.
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*FOR A LIMITED TIME we are offering 1 MONTH FREE on a 13 month lease on Studio Apartments ! 2116 Chestnut is the first new residential rental high-rise built in Rittenhouse Square in more than a decade! Taking advantage of the latest construction techniques, this building is stylish, → Read More
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Are you here to participate in one of our current school-based festivals? If so, choose your school and follow the instructions:
The struggle of black men and the choices they make to still make positive outcomes for the future.
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Newegg.com - A great place to buy computers, computer parts, electronics, software, accessories, and DVDs online. With great prices, fast shipping, and top-rated customer service - once you know, you Newegg.
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This review is from: Actiontec PWR511K01 AV500 Powerline Network Adapter Kit, Up to 500Mbps
Pros: I was hesitant about buying because I need to use in a separate circuit panel from the main house, but it is working fine. Also saw mention of newer circuit breakers tripping, but the new wiring and circuit breakers in my house have not tripped or caused interference. (And the circuit breakers have been so sensitive to some electronic dimmer units that we needed to downgrade one circuit to older breaker).
Cons: none yet.
Other Thoughts: Much better transmission than the Wi-fi I had been using.READ FULL REVIEW


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How can I not be full of contentment?
God is not a Man, that He would lie.
On a daily basis, His promises flow;
He is the Source, on Whom I can rely.
Despite the surrounding difficulties,
I've purposed to accept His sacred Word;
therefore, I will continue to stand firm,
by His grace and loving messages heard.
His everlasting mercies are renewed;
I remain girded by His faithfulness!
With the thankfulness of my frail heart,
I am still unable to wholly express…
the articulation of proper gratitude.
With empty hands, raised over my head,
I bow my heart in humble reverence,
while the grace of the scarlet thread
reminds me of the thankfulness I need.
Until the day that we are face-to-face,
I await with righteous anticipation
of being held by His eternal embrace.
Author Notes:
Loosely based on:
Rom 3:23; Phil 3:7-12
Learn more about me and my poetry at:
By Joseph J. Breunig 3rd, © 2014, All rights reserved.
© Copyright 2017 jjbreunig3. All rights reserved.
Status: Finished
Genre: Religion and Spirituality
Poem / Religion and Spirituality
Poem / Poetry
Poem / Religion and Spirituality
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A feline in Russia caused a stir when it was caught by prison officials strapped with a cell phone and trying to enter the facility.
Grumpy Cat is possibly getting his own movie deal and he couldn't be more upset about it.
Al Gore may have not won the election back in 2000, but this cat has never given up hope.
Earlier today in England, a 24 year old female zoo employee was brutally mauled by a tiger. Here's what you need to know
When Ty the tiger lost 100 pounds and still refused to eat, his handlers knew something was wrong.
Talking bacon and drunk cats on Valentine's Day? Trust us, they're far funnier than any Hallmark card you might buy.
Cats always land on their feet… even if they've only got two of them.
One volume of awesome animal photobombs wasn't enough? Well, here's a second volume unapologetic critters ruining photographs.
When you're stacking your cats in cages, you might just have too many.


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We all love A-List stars, but there are few things more exciting than catching a rising star at the beginning of his or her career.
After all, who doesn't love bragging to their friends that they saw someone's first movie and just knew they'd be big? And years later, when they have their big honorary Oscar award montage, won't it be fun to look back on the journey you took with that star, from fledgling neophyte to big screen legend?
Luckily, we live in a time that is boasting a great new generation of young actors and actresses, from teen stars to 20-somethings that have paid their dues and are shooting up to the top.
Here's a look at some of the most talented and promising newcomers to Hollywood stardom; let us know who else should be on the list!


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Confrontation Street [Import]
- (Portugal - Import)
- Artist: Squealer A.D.
- Format: CD
- Release Date:10/23/2006
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Now on the famous AFM label from Germany, this will be the hardest album in the bands history so far and it's music as well as it's lyrics reflect the aggression which rules the day to day life of millions of people in many countries at this point of time. The album was recorded and mixed in Gernhart Studios in Siegburg by Martin Buchwalter (Victor Smolski, Fire in the Attic, Perzonal War) and it was mastered in Monoposto Studios (a.o. Toten Hosen, Beatstakes) in Düsseldorf. Limited digipak version.
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