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Polyomavirus nephropathy (PVN) is a form of nephritis caused by reactivation of the human polyomavirus, BKV, in renal transplant patients. BKV is ubiquitous in most human populations and establishes a lifelong, subclinical, persistent infection of the kidney. In transplant patients and other immunocompromised individuals, viral replication leads to tissue damage and renal dysfunction. The incidence of PVN has risen dramatically in recent years concomitant with rising numbers of transplants being performed and the development of more effective immunosuppressive drug regimens aimed towards preventing rejection of the transplant. Presently, there are no effective anti-viral treatments for BKV, and therefore the clinician is faced with the dilemma of reducing the dose of immunosuppressive drugs to allow the patient's immune system to battle the virus, which then raises the risk of graft rejection. The biology of BKV in human renal epithelial cells is beginning to be uncovered, and a better understanding will be critical in the design of therapeutic approaches. Using an in vitro cell culture system for the propagation of primary human renal proximal tubule epithelial cells that allows them to maintain their differentiated function, key features of the BKV life cycle can be studied. BKV replicates efficiently in these cells. Treatment of the cells with interferon-?, however, inhibits viral gene expression and, therefore, replication.
The aims of this project are to utilize this in vitro system to characterize the mechanisms that regulate viral replication, including an analysis of viral chromatin and subnuclear localization of the viral genome under replicating and non- replicating conditions. In addition, the pathway that the viral particle takes from the plasma membrane to the nucleus of the cell, during which it begins to disassemble, will be examined. The long term goals of these studies are to dissect the mechanisms that regulate BKV replication in renal tubular epithelial cells and to identify steps in the viral life cycle that may be amenable to the development of new antiviral drugs.
BK virus is a virus that infects nearly everyone during early childhood but does not cause any disease in healthy individuals. However, in kidney transplant recipients the virus can reactivate from an otherwise dormant state and cause a destructive disease of the kidney. Up to ten percent of loss of function of transplanted kidneys is thought to be due to BK virus and there are no drugs available with which to treat the infection. BKV can also cause severe bladder disease in bone marrow transplant patients. Therefore, it is the goal of this project to understand more about how the virus infects cells in the kidney and urinary tract, which should lead to the identification of new targets for anti-viral drugs.
|Imperiale, Michael J (2014) Polyomavirus miRNAs: the beginning. Curr Opin Virol 7:29-32
|Broekema, Nicole M; Imperiale, Michael J (2013) miRNA regulation of BK polyomavirus replication during early infection. Proc Natl Acad Sci U S A 110:8200-5
|Bennett, Shauna M; Jiang, Mengxi; Imperiale, Michael J (2013) Role of cell-type-specific endoplasmic reticulum-associated degradation in polyomavirus trafficking. J Virol 87:8843-52
|Broekema, Nicole M; Imperiale, Michael J (2012) Efficient propagation of archetype BK and JC polyomaviruses. Virology 422:235-41
|Bennett, Shauna M; Broekema, Nicole M; Imperiale, Michael J (2012) BK polyomavirus: emerging pathogen. Microbes Infect 14:672-83
|Jiang, Mengxi; Entezami, Pouya; Gamez, Monica et al. (2011) Functional reorganization of promyelocytic leukemia nuclear bodies during BK virus infection. MBio 2:e00281-10
|Swimm, Alyson I; Bornmann, William; Jiang, Mengxi et al. (2010) Abl family tyrosine kinases regulate sialylated ganglioside receptors for polyomavirus. J Virol 84:4243-51
|Broekema, Nicole M; Abend, Johanna R; Bennett, Shauna M et al. (2010) A system for the analysis of BKV non-coding control regions: application to clinical isolates from an HIV/AIDS patient. Virology 407:368-73
|Abend, Johanna R; Low, Jonathan A; Imperiale, Michael J (2010) Global effects of BKV infection on gene expression in human primary kidney epithelial cells. Virology 397:73-9
|Jiang, Mengxi; Abend, Johanna R; Johnson, Silas F et al. (2009) The role of polyomaviruses in human disease. Virology 384:266-73
Showing the most recent 10 out of 19 publications


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Willie Geist: "There's been many overblown claims of tyranny and abuse of power from the government over the last few years…This is tyranny. If this is the government, a nonpartisan agency coming after specific groups, this time it's real."
Comment count on this article reflects comments made on Breitbart.com and Facebook. Visit Breitbart's Facebook Page.


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|Rollerfly Plastic Replacement Balls 100-Pack
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text: There's Cosplay And Then There's Building An Oil Tanker In The DesertAndrew P Collins5/05/16 3:33pm4110EditPromoteGo to permalink "Wasteland Weekend" is a Mad Max-style ComicCon that goes down in the desert. You know, for realism. Our man Sweet Lips here got into Wastelanding with pirate-themed bitchin' Camaro, then upgraded to a damn sand-sunken Exxon Valdez.


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Publisher's Description+
From Pocket Island: Think about it! Your ringtone can tell a lot about you! Discover one more way of self expression with new Ringtone Volume Amplifier! If your ringtone is just a sound that indicates the incoming call and you never cared to change it for as long as a whole year then this application is not for you.It is a promising application for those who have style and consider their ringtone a trendy accessory and a part of their image. People that meticulously work to create their own style will be pleasantly surprised by the expanded abilities of the Ringtone Volume Amplifier. Cut ringtones out of favorite music themes, sound tracks and mixes, amplify the cuts and create your own records without ruffle or excitement is it not a dream come true? The software interface is perfectly organized to make the ringtone creation process most comfortable and pleasant. > Import the chosen theme from the music collection of iPod/iPhone. > Cut a piece up to 40 seconds long > 4-fold amplification. > Trial hearing of the chosen part before conversion. > For enthusiasts, there is an option that allows you personally record a piece with a mike, cut the unwanted stuff off and adjust the volume. > You can easily export the ready piece and make it your ringtone. > You have an option to transport the file to your favorite Facebook or Twitter.> Send the processed music file to your email or straight to your PC via Internet browser.So, if you see the Ringtone Volume Amplifier application in your device congratulations! You own a powerful ringtone factory. Dont forget that each contact in your list can have its own ringtone that you want to hear when the person calls you. With Ringtone Volume Amplifier what ringtone it would be is only up to you to decide! Ringtones cant be too many! Let hundreds of unique hand-made ringtones brighten up your device and play their part in creation of your flawless style.
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Well - I went out and bought the Sapphire version of the card. The drivers work nicely, and the fan slows to 3% at idle (47C) so very nice! However, it is still clearly audible in my system. I also bought the Accelero S1, but I don't know if I should mount a fan on it, or if it can even be mounted on the 4670 at all.
Edit: I did end up mounting the S1. Very pleased. Completely silent, idles at 40C and only gets up to 55C in a hot room.


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The rise of Laura Robson moved up another notch when she survived one of the most severe cases of Centre Court ordeal by adulation since Tim Henman called it a day.
There was also a swift bonus hard on her victory over Columbia's Mariana Duque-Marino. It came with the unexpected fall of the seventh seeded – and world ranked – German Angelique Kerber, who was suggesting formidable opposition next week if Robson happened to fight her way through to the fourth round.
Yet if the 19-year-old Robson is now firmly established as the latest object of Wimbledon worship in all its cloying frenzy, if she has the strength and self-belief that has already ambushed some of the big names of the women's game, you were still bound to ask a hard question after her joyously received triumph over an opponent who, quite frankly, looked distinctly flattered by her world ranking of 117th.
The 23-year-old from Bogota fired shots of dismaying inconsistency before Robson – a 6-4, 6-1 winner in one hour, 13 minutes – was required to bow to a standing ovation.
Yes, Robson came through the crisis of a broken serve in the third game of the first set and eventually she produced some of the natural, thumping power which brought her such major scalps as Kim Clijsters and Li Na at the US Open – and has also claimed 2011 Wimbledon champion Petra Kvitova.
Yet while Robson talked happily of picking up 20,000 new Twitter followers as a result of a message sent by One Direction's Harry Styles, there was certainly a sense of impending questions about the weight of pressure being applied at her place of work.
There were huge groans when Robson double faulted and surrendered her serve, and that extreme was matched by the jubilation which came when she found her way home.
After reporting that her mother was still absent in Greece but had sent her a message of congratulations, Robson insisted that she did not see too many hazards in the rising level of attention paid to everything she does and says, even after her Twitter mistake in failing to correctly identify fans of her admiring pop group was pointed out.
"I think I'm handling it [the crowd pressure] pretty well so far. I've had a fair few matches in big stadiums now where I've handled the crowd support perfectly fine. You know, I love when people get involved. Sometimes they do like a massive groan if I hit a double fault, but I'm doing it as well. So, yeah, we're just living it together."
In fact the synchronisation was less than perfect when Robson quickly fell out of the rhythm of her serve. Yes, she agreed, there were problems with her timing but it was a routine problem and nothing do with nerves. "You know, I thought I handled it well today. I managed to break her at the end of the first set, which was big. And yeah, I just kept it together."
There is certainly no lack of commitment or force. Robson may not be extravagantly gifted in terms of the range and the spontaneity of her game but the more that is seen of her at the higher levels the less of a mystery it is that she is among the elite of Junior Wimbledon winners, a player who has been earmarked for a significant career by no less than Serena Williams.
The winner of 16 Grand Slams was asked about Robson's chances of making the world's top 10. Williams insisted they go higher than that, a theory which plainly filled Britain's No 1, and the 34th ranked player in the world, with much pleasure – even it brought another turn of pressure.
"It's very nice of her," said Robson. "She's obviously the best player of all time. Yeah, it means quite a lot. But I do understand that what I have to do is focus on the next match rather than how soon I might be in the top five or the top 10.
"I think it just takes a lot longer to get to the top now. You have to have a lot of confidence. You know that for a long time you have to keep your expectations low because you're going to have a lot of tough matches."
Inevitably, we are back with the screams and the groans of the Centre Court – and the fact that the prime minister found time to send her a congratulatory tweet after the first-round victory over the 10th seed, Maria Kirilenko.
Again, Robson is defiant of claims that there is a danger that she could be engulfed. "When I'm on court, I'm not worried about who's tweeting me. I'm really focused on the game plan that I have. After a match, I'll go through it all. But the truth is that it doesn't bother me at all."
She is much more concerned, she says once again, with the burden of performance than anyone's expectations but her own. It is as heavy as ever today when New Zealand-based Marina Erakovic is expected to produce a much more severe challenge than that delivered yesterday.
"I've lost to her on grass before," said Robson. "She's got a big game, a huge serve, a good slice as well, which is pretty much a perfect game for grass. Yeah, I know it's going to be a tough one. Her net game is on the ball. Yeah, we'll see how it goes."
There is, though, another inescapable reality to be faced once again today. It is that such nuances of an opponent's style, and the peculiar pressures she will bring to the court, are hardly likely to be high in the attention of an adoring crowd.
There are good reasons to believe in Laura Robson. She has power, which has already claimed a high quality of victim. She is a natural fighter who hits the ball extremely hard. The trouble, though, is that she has already been anointed. It is something that happens in this place too frequently, too quickly, and, with depressing regularity, too hazardously.
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text: Sex And The City-Inspired Cigarette Ads Die Early DeathJessica11/28/07 9:30amFiled to: snuffed outCamel No. 9r.j. reynoldsCigarettes68EditPromoteShare to KinjaToggle Conversation toolsGo to permalink Print advertisements for Camel No. 9 Cigarettes, the pink-packaged smokes meant to evoke Chanel No. 19 and appeal to the Manolo-obsessed and Cosmo-swilling female consumer, will be pulled from magazines by parent company R.J. Reynolds beginning in 2008. Executives for the company tell the Winston-Salem Journal that the decision to pull all print ads is not based on Congressional protests, but merely a "business decision." According to the AP, the initial protest — which focused on tobacco advertising in women's magazines — was launched because Camel No. 9 ads "threaten the health of the teenagers and young women who form a large part of [women's magazine] readership." We Quit...For Now [WWD, sub. req.] RJ Reynolds to Stop Print Ads Next Year [ABC News] Earlier: R.J. Reynolds Thinks Women Are Superficial. They May Be RightReply68 repliesLeave a reply


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Drag to set position!
Group Since August 27, 2006
|Last Replier
|Latest Post
|Does anyone comment?
|10 years ago
|does cheesecake count?
|Sam BreachPRO
|10 years ago
Group DescriptionWell it had to happen eventually; having 'cake' as the photo theme I mean. This round we look to that old Queen with the big hair (and I'm not talking Elton John!). I am thinking cake – which means cream-laden gateaux, fluffy jam-lined sponges, cup-cakes and other little dainties through to huge slabs of chocolate, carrot, cheese and fruit cakes. Then there are candle topped birthday cakes, wedding cakes and the like. Careful you don't stray over into puddings and no buns, biscuits, cookies, tray bakes or muffins!
Time to bring into play those cake stands, fancy plates, doilies and cake slices. Or you could go the other route and aim for that 'just out of the oven' baked at home look.
Entry Guidelines:
- Only pictures with a somehow food/drink related CAKE theme should be added to this Foodography 9: we will remove those that are not.
- Only pictures taken specifically for this Foodography challenge will be accepted. Any images taken or loaded to Flickr before September 1st 2006 will be deleted.
- Up to 4 Foodography entries per person please. Edit your entries before you submit and choose to showcase just your favourites on the subject CAKE. The challenge is open til mid October so there is plenty of time to experiment and play with the theme before uploading your favourite images.
- Foodography is generally open to constructive critique, to help us improve our food and drink photography skills.
- If you do not wish your Foodography entry to receive a critique enter NO CRITIQUE in the description. Otherwise, by default, you should expect critique from fellow members.
- IMPORTANT: If you are expecting Foodography critique, please initiate discussion about your own entry by adding your own critique first, to your submission. Outline what you like about your picture, what you were trying to achieve, what you think works and where you think there are areas for improvement.
- The Foodography challenge is to take a picture on a theme, not to pick one from an archive.
- Foodography was created for food bloggers but anyone who is into the idea is welcome to join in.
- Please Note: After the deadline, people will still be able to upload pictures to this group but it will no longer be administrated and there will be no active critiquing going on.
Additional Info
- Members can post 4 things to the pool.
- Accepted content types: Photos, Videos, Images, Art, Screenshots
- Accepted safety levels: Safe


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Let's Make Today Awesome
I know I sound like that lame motivational speaker you had in junior high school, but just hear me out.
I know I sound like that lame motivational speaker you had in junior high school, but just hear me out.
The holiday season is upon us and it's so easy to get stressed out about everything that needs to be done. Here are a few creative ways to unwind and clear your mind.
I love food. Sometimes, I love food more than I like most people. I eat with gusto and love to play with recipes. Here are a few ways to give the gift of food.
Thanksgiving can be a good time to introduce someone important to your family. I did it with Glen. Everyone was there in one place so it just made sense. Here are a few ways to bring a date to Thanksgiving without it being a disaster.
You know I'm all about doing as much stuff online as I can. Sometimes it's just faster and easier and now it can save us money!
The holiday shopping season is upon us and I don't like going to crowded stores with rude associates and empty shelves. I like staying inside where it's warm and shopping online. Here are a few online shopping scams to watch out for and how to avoid them.
One of the most stressful times of the year is coming up. Here are a few pointers for a low stress holiday season.
Everyone seems to gain weight through the holidays, myself included. I always chalked it up to the colder weather and that metabolism slowed down over the holidays. Turns out it was just me that slowed down. Here's how to get through the holidays without gaining a spare tire.
Looking for a job? Here's how to do it while you're still employed.
This year, like years past, kids probably got a lot more candy than they can eat before next Halloween, so here are a few things that you can do with the candy your little ghosts and goblins can't eat.
As shoppers make a mad grab for stuff, shoving anything and everything into their carts and figuring out whom to give it to later, there are some things shoppers should stay away from.
Most will tell you not to even put it in your mouth, but these cool dentists are here to tell you what to eat because it's the day after Halloween and they know you're going to do it anyway.


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Is Stoneburg Cove Resort incorrect or missing key business information? Update your Hotfrog listing today.
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Hotfrog Canada provides information regarding Stoneburg Cove Resort in Carrying Place ON. Stoneburg Cove Resort is located at 59 Carter Rd, Carrying Place ON K0K 1L0 and provides Travel services. Contact them on (613) 475-0765.
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The love of a mother. From the moment you are conceived, you know that there is someone special awaiting your precious arrival to the world. Someone who will love you despite all of your flaws and whose love for you is the most important gift of all. The person who will starve for you and dedicate their entire lives to you, just to ensure your health and happiness. This person will be there for you no matter what the circumstances are, and you know that you can always depend on them to smile. This is the person who brought you into this world, your dearest mother. Your mother who survived through a difficult nine month pregnancy and an even harder labour process, with the intentions of giving you their all. Your mother knows all the potential risks of having a child, but she also knows that the warm feeling in her heart when she sees your eyes twinkle is worth all of her struggles. Mothers are the most beautiful, kind-hearted, and caring people there are in this world. They lose sleep over your crying nights as a baby, and they know just how to make you feel better no matter what you're going through. It's that inseparable bond a child has with their mother that makes that love so strong. Mothers love their children even when they are defiant and unreasonable, and they always have room in their hearts for forgiveness. The effort they put into everything they do and the way they are ready to just drop whatever they're doing at any time to help you is remarkable. That patience and care that they have and their ability to nurture is something only a mother holds. The feeling of having someone to talk to at all times who is always ready to listen and help you is unexplainable. A mother is someone who always wants what is best for their child, and they live to give their child advice and wisdom. A mother's work takes more effort than any other job out there. Mothers deserve all the appreciation in the world for the work they do, while always having a smile on their face. That positive and uplifting personality that you will never forget. A mother is more than just a best friend... a mother is everything. Appreciate everything your mothers do for you and love them infinitely. -Bethany Sousa
© Copyright 2017 bethanysousa. All rights reserved.
Status: Finished
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Miscellaneous / Health and Fitness
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"Matt, 23, Not Really Prince Harry"
In one classic fairytale, a ghastly beast turns out to be a handsome prince. In another, a frog is in fact a handsome prince. In "I Wanna Marry 'Harry'," FOX's new reality show that premiered tonight, the handsome Prince Harry of Wales turns out to be a random British kid named Matt. Will the girl still want him when they learn he's a pauper? Better than an amphibian, but still: Despite the fact that the word "fairytale" is said almost a dozen times in the first 10 minutes of the premiere, this story is far more similar to a teaching fable.
Twelve American women...young women...girls, really (the most senior in the bunch are 25 and referred to as "oldies"), are brought to a castle in the UK and told nothing about the man who's eye they'll compete to catch. Meanwhile, we enjoy a montage of Matthew Hicks, 23, who really does resemble Harry, learning to pretend he comes from the House of Windsor instead of nondescript flat.
He can't afford a car, so rides his bike to his job cleaning up oil spills. He's fit, humble and more handsome than Harry. The producers (including Ryan Seacrest) hit the jackpot. As for the ladies, it's more of the same: we have the loud one, the catty one, the drunk one, the old one (at 25!). Yet, "The Bachelor" franchise — with its perfectly polished, family-oriented, trained and molded dolls — this is not. These women seem to have been chosen specifically because they might go off the rails. This show may be the frog that turns out to be a thoughtful (if unintentional) investigation: into the differences between English aristocracy and the slums of American culture, reality television.
One refreshing thing about this morally-unclear debacle: a bachelor who doesn't think he deserves be there. Whether because actually humble, told to be, edited to be, or simply British, Matt actually is charming. He thinks they're all out of his league. And, considering what most are after (fame and money), he's right.
He's presented as adorable, particularly during a montage in which he's taught, by a hilariously fake butler character named Kingsley, which fork is for what and how to shoot skeet, among other supposedly royal trappings. We see Matt — whose slug, appearing under his name during confessionals, is "Matt, 23, Not Really Prince Harry" — exclaiming that his fencing uniform has given him a "massive front wedgy."
So far the front runners appear to be 1) Kimberly Burch, from Long Island, who's as normal as a reality-show contestant can be; 2) Meghan, from SoCal by way of Dallas, who thinks she deserves whatever she wants because, "I cook and clean, and look bangin in a bikini;" and 3) Rose, who's a hot mess in the best rubbernecking sort of way.
Matt and the women first meet at a masquerade "ball" on the castle's lawn. He avoids pointed questions and doesn't even reveal his name. Then, at the stroke of midnight, they each unmask one at a time. A mask analogy on a reality show! Is this dreck or high lit? I can't tell.
Matt chooses Rose to stay in a fancy "adjacent" suite in the castle (he thought with his shorts). And he sends home Leah, who also, sadly, seemed kind of normal.
It's tempting to spend these recaps simply mocking the show (and, honestly, I probably will). But I'm not certain who the target should be. The women, for their cattiness? The bachelor, for his duplicity? The producers, for their evil genius? Myself, for watching it? My heart wants to see Kimberly win; the bully in me is pulling for Rose just for the spectacle; the skeptic in me knows it's all fake anyway and hates that after one 40-minute episode, I'm already like, "Aw, she's cute" or "Whoah, she's a train wreck."
Ultimately, it's not much different than any other reality show: people pretending to be people they're not. At this point, I'm hoping for a surprise ending, in which we discover that one of them actually is royalty — Kingsley.


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Aston Martin / Ferrari Driving Experience£49 for a 3 lap supercar experience, £99 for 9 laps in 3 cars from Group A & B, or £129 for 9 laps in 3 cars from any group at Supercar Test Drives
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Opened today. This has spring bloomed before, but not other seasons.
Too dry I guess. Nice color impact from a distance - wouldn't have paid
any attention to it during spring bloom, but nice this time of year.
None of the 'typical' cycle rebloomers have started to show any signs of
making stalks here yet, so I guess this is still 'summer' bloom.
Linda Mann east Tennessee USA zone 7/8
East Tennessee Iris Society <http://www.DiscoverET.org/etis>
Region 7, Kentucky-Tennessee <http://www.aisregion7.org>
American Iris Society web site <http://www.irises.org>
talk archives: <http://www.hort.net/lists/iris-talk/>
photos archives: <http://www.hort.net/lists/iris-photos/>
online R&I <http://www.irisregister.com>


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Using soy wax as a resist is an exciting way to introduce color, pattern and texture in your work. Soy wax has the benefits of melting at a lower temperature and being much easier to remove than traditional batik waxes. In addition soy wax is sourced from a renewable resource and helps to support our farmers.
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A chat with Jeff Petry
Jason Strudwick
December 05 2012 04:25PM
I believe Petry is and will be a big part of this Oiler defense moving forward. With his ability to skate, move the puck and be good defensively he is a minute-eater. Every team needs these types of guys. He is good on both the power play and penalty kill.
He has not reached the ceiling for his development and Oilers fans should be very happy of that.
Jason Gregor
December 05 2012 11:22AM
In case you forgot what NHL hockey looked like, or the potential of Ryan Nugent-Hopkins, that was the highlights of his five-assist game v. the Chicago Blackhawks. Some Taylor Hall kid wasn't bad either that game potting a hat-trick in the 9-2 drubbing of the Hawks.
Both Hall and Nugent-Hopkins were having a check up this week, but before you freak out keep in mind that the Oilers wanted to use the break in the OKC Barons' schedule to let their doctors look at both of them.
It's nice to be wrong
Jonathan Willis
December 04 2012 10:59PM
An NHL lockout is a cynical business, with two extremely rich parties fighting for a wicked pile of cash. The most recent edition has been particularly galling, with two sides seemingly able to agree on a myriad of issues but unwilling to bridge the small gap between them.
Given that, naturally I was cynical about the December 4 meeting between players and owners – without the presence of league commissioner Gary Bettman or NHLPA executive director Donald Fehr. I thought it likely to be an empty ploy without hope of succeeding. And to be clear: it hasn't succeeded yet. But for the first time in quite a while, things are looking up.
Robin Brownlee
December 04 2012 05:24PM
Is anybody else just a little bit nervous about the state of the left shoulder of Ryan Nugent-Hopkins? I thought so.
December 04 2012 02:48PM
"When you're at the end of your rope, tie a knot and hold on" ― Theodore Roosevelt
So something called a Steve Burton - a CBS reporter from Boston who has been right about some stuff in the past - went on Teh Twitterz and said that the lockout was going to end in the next couple of days. Then we get all excited and then Bill Daly comes out and says that this is absolutely false.


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Outlook How do you protect workers in a recession? If you are a Tory adviser, such as Adrian Beecroft, you strip them of all rights so that it is possible to keep them employed at much cheaper rates. Which will ensure employment rates stay high.
Reassuringly, Beecroft, David Cameron and George Osborne all go for this personally under the terms and conditions of their own employment. There's proof that it works (don't ask where, there just is).
So it is with some disappointment we report that, I quote Reuters, "France's new Socialist government is planning labour regulations in the coming months to ramp up the cost of laying off workers for companies, its labour minister said after data showed the jobless rate has hit 10 percent".
This crazy guy's response to rising unemployment is to make it harder to fire people. Is he not aware of the British economic miracle?
The French Labour Minister Michel Sapin said: "The main idea is to make lay-offs so expensive for companies that it's not worth it."
This will clearly inhibit economic growth. Which was otherwise soaring. Honestly, have they not learned the lessons of the banking crisis?Reuse content


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|Help and Advice
|Transit of Mercury 2016
|Giving long exposures on a digital camera
|Photographing star trails
|Predicting the ISS and other satellites
|Using a mirror to view a partial eclipse
|Simple Guide to Viewing the Space Station
|Choosing a Telescope
|Tips when projecting the Sun
|Starting to Use Your Telescope
|Imaging with a DSLR through the telescope
|Buying a telescope for a child
|Photographing a partial eclipse
The stars are out. It can't be all that hard to learn the sky, can it? But then you get out there and the stars all look, well, starry. So what's the secret? Read on and find out.
But before you do anything these days you have to carry out a Risk Assessment. Being eaten by a ravenous wild animal? Hasn't happened yet. Being scared out of your wits by next door's cat suddenly jumping on you? That's more likely, assuming next door have a cat. Being frozen to the guts? Even more likely this weather, but at least you can do something about that one by putting on two of everything (within reason, of course).
You will need a star map, and you will need to know how it works. This may seem obvious, but there is a knack to understanding these things. Here's our map for this month:
All maps produced using Stellarium software.
Now don't write in and tell us that we have the points of the compass all wrong. This is a map of the sky, so it shows what's over your head which reverses all the directions. If you hold it over your head, east and west will be the right way round. Easy enough with a phone or a tablet, but not recommended with a desktop computer. Maybe that should go in the Risk Assessment as well.
It shows the whole sky, so the scale is quite small. Normally you turn to see different parts of it, so to see the view looking north, for example, hold the map upside down with north at the bottom.
The map shows the sky in mid month at about 7.30 pm, at the start of the month at 8.30 pm, or by the end of the month at 6.30 pm. All times are GMT.
|TIP If you aren't sure of the direction of north from your location, click here for a page on Getting Your Bearings.
At this time of year one of the best constellations (star patterns) of all is in the sky – Orion. Look just to the left of your south point and you should spot three stars in a line, with four other stars forming a sort of box around them, as shown on the map below.
Orion has more bright stars than any other constellation, so it shows up no matter how bad your light pollution is. You can't mistake it for anything else in the sky. As well as the three stars in a line there are two brighter stars, called Betelgeuse and Rigel, at top left and bottom right.
The three stars in a line are known as Orion's Belt. Orion is meant to represent a hunter, usually facing westwards towards Taurus, the Bull. Dangling from his belt is a sword, which is the line of fainter stars just below the belt where the map is marked M42.
You can follow the Belt stars up and to the right (the west) to the bright star Aldebaran, in Taurus, and beyond that to the best star cluster in the sky, the Pleiades (pronounced Ply-a-deez). Then following the Belt stars down and to the left you get to Sirius, in the constellation of Canis Major, the Greater Dog. Sirius is the brightest star in the night sky (note: smart-alecs love to point out that the brightest star in the sky is the Sun so you always have to be vary careful to say the night sky to avoid giving them the satisfaction of doing so).
Also look out for Auriga, some distance directly above Orion. Its brightest star, Capella, is almost overhead from the UK at this time of year. There is a little group of three fainter stars just to one side of it. There are four other stars in a big pentagon making up the rest of the constellation.
Above and to the left of Sirius is Procyon, then high up above Procyon is a pair of stars called Castor and Pollux. When you have stopped sniggering, we will just say that these are the main stars of Gemini, the Twins. Click to find out more about these stars and the constellation.
For a star map that shows all the constellations and their names, click here.
In the early evening we have brilliant Venus in the western sky and Mars just to its left. At the start of the month they are close together, but after the first week Venus stars to drop away from Mars as it gets closer to the Sun as seen in the sky.
After midnight and in the early morning skies you'll see a bright star over in the eastern sky which is Jupiter, the largest planet in the solar system. Next April it will be rising earlier and will be at its closest to us for the year. Then during the summer it will a good object to spot in the early evening, though slightly farther away. It's worth looking at it through binoculars, as you should see three or four of its moons like tiny stars on either side of it. With a telescope you can see a couple of its dark equatorial belts as well.
Saturn is very low in the early morning sky in the east just before sunrise.
It begins the month just after New Moon which was on 28 January, when it's in the same part of sky as the Sun and isn't visible. You will see a thick crescent after sunset over in the west on the 1st, when it is just to the right of Venus. First quarter – that's a half Moon – is on the 4th and then full Moon this month is on the 11th. Last quarter on the 18th, then the month ends with New Moon on the 26th.
We have a whole section of this site about the Moon and what to observe.
OK, you've read all this for nothing, now comes the plug. This page is brought to you by the Society for Popular Astronomy, which is a really great society to join. It's based in the UK but there are members in other countries as well. It doesn't cost much to join, and there is a special rate for Young Stargazers. At least take a look at what we have to offer.
Text by Robin Scagell


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Optimality Theory
By (author) Rene Kager
Series edited by P. Austin J. Bresnan
Format: Paperback
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Optimality Theory by Rene Kager
Book DescriptionThis is an introduction to Optimality Theory, whose central idea is that surface forms of language reflect resolutions of conflicts between competing constraints. A surface form is 'optimal' if it incurs the least serious violations of a set of constraints, taking into account their hierarchical ranking. Languages differ in the ranking of constraints; and any violations must be minimal. The book does not limit its empirical scope to phonological phenomena, but also contains chapters on the learnability of OT grammars; OT's implications for syntax; and other issues such as opacity. It also reviews in detail a selection of the considerable research output which OT has already produced. Exercises accompany chapters 1-7, and there are sections on further reading. Optimality Theory will be welcomed by any linguist with a basic knowledge of derivational Generative Phonology.
Buy Optimality Theory book by Rene Kager from Australia's Online Bookstore, Boomerang Books.
Book DetailsISBN: 9780521589802
(228mm x 152mm x 30mm)
Pages: 466
Imprint: Cambridge University Press
Publisher: Cambridge University Press
Publish Date: 28-Jun-1999
Country of Publication: United Kingdom
Other Editions...
Books By Author Rene Kager
Prosody-Morphology Interface, Paperback (June 2010)
Leading linguists address various issues in the interaction of word formation and prosody.
Constraints in Phonological Acquisition, Paperback (April 2009)
A 2004 overview of linguistic research into acquisition of phonology, focusing on constraints in phonological acquisition.
Optimality Theory, Hardback (June 1999)» View all books by Rene Kager
First ever textbook on Optimality Theory, a major new area of linguistic theory.
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text: All applications must be submitted on or before Monday, June 6, 2016 by 5:00 pm - no mailed or hand delivered applications will be excepted. Please read the Application instructions and the Community Development Program Design. All attachments must be submitted with the online Application. Please be sure to thoroughly review the entire Application for completion, errors, or omissions prior to submitting the Application.


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Gameforge has reportedly restructured and has laid off one hundred of its four hundred plus employees. According to CEO Alexander Roesner, the move will "optimise our use of resources and great potential for further growth increase".
The report at GamesIndustry.biz also reveals that Star Trek: Infinite Space could be in developmental trouble unless a co-publisher is found for the title.
Gameforge reaches 300 million users worldwide according to its own internal data.
Read the full article at the link above.
What a shame.
Star Trek Infinite Space development has been suspiciously quiet for sometime now which normally only means one thing.
But, there's 300 million registered users... oh wait, it's a meaningless stat on a F2P game.


text:
In March of 1886, at the age of 26, acclaimed Russian author and physician Anton Chekhov wrote this fascinating and honest letter of advice to his troubled older brother, Nikolai.
Anton Chekhov
The War on Insincerity
Melita Caulfield is waging war on something that is often considered socially acceptable.
We Don't Talk: Jovan Belcher and Kasandra Perkins
Liam Day wonders if the tragedy in Kansas City was a part of society's expectations that men be strong and silent.


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Chrysler Cirrus QuestionsRefine by vehicle
Just purchased a seldom used 1997 Chrysler Cirrus. only 30K original miles. ride is really firm. Is this normal or is there an issue with the suspension from lack of use?
Getting fire but won't start
Drove car,stopped went to restart an won't start back
Drove 30 mi an stopped.30min later went to leave.started car and went to pull up an out of drive an it died an won't start bk.sound like it's trying to start but won't.
The black plastic line blows off might be a week or 2 months. Put new clips on can pull on the line and it's on good then out of the blue pop it's off
The automatic door locks keep trying to lock when the dome lights flicker off and on.
The car runs and sounds fine when first started. After a few minutes, it starts having a whistling type noise and a scrubbing king od noise that sounds like metal on metal. I had several people tell me it sounds like brakes but it makes the noise when brakes are not being applied. The repair shop says brakes are fine. Passenger side rear wheel is very hot after driving for a short distance and there is a burning smell.
Also had no spark replaced crank sensor tryed to start once with either now no spark either
I have replaced the front rotors 2 times and the calipers, and pads. At about 40mph, I am getting brake vibration like the rotors are bad. It is on both front wheels What could be causing this? What should I replace next?
noise isn't at starter
the check engine light doesn't come on at all. I'm told for this model it comes attached to a cluster which I found at dealership but can I install this myself? is it just that simple to remove dash and replace?
replaced the hvac control module because the resistance check found resistance did not change when control module shifted to any position. replacement module has correct resistance, but no change.
It's not running well and needs to be repaired..
Just won't fire had been stalling alot before it got where it just won't start
The car turns over but won't start can't smell gas even when you keep pumping gas peddle.
Seems to run good at other speeds. It is much better but am afraid if I don't get this misfire fixed it will stop up another catalytic converter. Any help or ideas will be appreciated!!
At times when I start my motor, the gauges all work fine (gas, wiper, heater, air conditioner). But now and then when I start the motor the gauges do not move and I get nothing. The air does not work, or the heat, or the wipers or gas. What is causing this? I have checked for loose grounds and loose wiring.
The light where the cup holders between the driver and passenger is intermittent at best and I would like to replace. I would also like to replace the light that illuminates the gears 'P','R,'N''D',etc. That one is completely out and if it's something that isn't too complicated to do then I would like to put a new light in there as well.
I have a 2000 Chrysler Cirrus, at first when it wouldn't start I replaced the fuel pump and it started. 2 weeks later same problem. Replaced it and it started. I'm on my 4th fuel pump and new filter. This time she wouldn't start. A hose was replaced & she started multiple times. Drove to the store, returned home prepared to leave out again she turned over and cut back off. Now she won't start. It's like it's not getting gas.
not running hot, no other lights or indicators
Ran self-diagnosis and gauges appear to be working correctly.


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in 1994 to take over the partnership business of its predecessor,
ALLWELL Narrow Fabric Industri…
THE CREATIVE BEHIND THE LENS Not just photography . We are here to capture the best visuals. To be visually creative and to translate precisely thoughts and forms into vivid images of magnificent value. At Effect Visu…
The manufacturer & supplier for precision turning & milling part,electronic,automobile part,fax machine.
Parts & Services
we offer safety shoes,safety boots, work shoes, work boots,safety footwear,rigger boots,pvc safety boots,men's safety boots,china safety shoes, steel toe boots,steel toe shoes,workwear,safety goggle,welding gloves,safety…
Safety Helmet
Established in 1978, SAFE INDUSTRIAL PRODUCTS SDN BHD specialises in the marketing and servicing of assorted pumps and valves catering to the General Industries. With 30 years of experience behind us, we are always c…
We have more than 30 years experience specialist in transport and trading, achieving customer's satisfaction and deliver your goods in time. Our reasonable price and the efficiency services are your best confidence.
Transport ServicesTransport AgentsLorry TransportTransport
Services: Petrol & diesel engines Factory maintenance Marine & Industrial automation Machinery erection, installation & repairs Steel structure fabrication/ construction Spare parts supply Rental of equipmen…
Kluang, Johor
GPRO Shopfloor Data Tracking System (G.PRO SDT) is designed to improve your production line productivities and worker's efficiencies by eliminating processing wastes and improve work methods. An automative data capturing…
Fasteners : Bolt, Nut, Screw, Washer, Stud. Material : High Tensile, Mild Steel, Copper, Brass, Aluminium, Stainles Steel. Hand Tools : Mr.Mark, Elora, Jonnesway. Chemical : Loctite, PH7 Hand Cleaner, Starwill
Metal FastenersScrew Machine ProductsCopperFasteners
Pasir Gudang, Johor
KONG LONG HUAT signifies "FAIRNESS, PROSPERITY AND TOGETHERNESS" in our dealings with Customers, Business Partners and Employees
Rubber ChemicalsChemical CompanyAcidChemical
Pest Contol System, Termite Treatment in Kulai, Johor for Hotel, Industrial, Commercial Building, Wet Market, Residential., AGR Environmental Service Sdn Bhd, kulai, Johor
With a strong, capable and professional workforce, we managed to tap into the rapidly developing market of Malaysia and acquired a growing list of prestigious clients along with their illustrious projects
residentialMechanical EngineeringCommercialContractor
Pontian, Johor
NCI Industries offer a wider range of household products from confectionery moulds, containers, bottles, basic furnitures, kitchenwares, microwavable, storage & cabinets as well as stationery sets to meet your everyday n…
To rental skylift from 16m - 54m, and mobile crane 20t - 160t (tel : 012-7313158)
We offer fully integrated services including valuation advisory and consultancy, strategic consulting and market research, agency, property and asset management as well as project coordination to property owners, in…
Dealers in Waste Scraps, Plastic & Waste Paper and Factory Waste Collecting Service.
Bukit Bakri, Johor
M & R Manufacturing - malaysia window clamp, top plate, precision engineering, jig & fixtures, trim & form, tool & die, mould cavities
Engineering, Electrical, Hardware, Industrial and Estate Supplies
We, Dowin Real Estate Agency, not represant the developer or the management corporation of Pan Vista but the marketing agent for some of the units at Pan Vista Our first office which is headed by Mr Richard Sha…
AgentIndustrial real estateContractor
Kluang , Johor
Industrial, Engineering, Estate and Electrical Supply
Kuala Lumpur, Johor
Brass Machine Screws Brass Screws [x] Brass Nuts Fasteners [x] Jamnagar India Brass Components [x] Brass Hose Barbs Hose Fittings [x] Copper Screws [x] Brass Casting Fittings Foundry [x] Stainless Steel Baskets [x] Stain…
Metal FastenersEarthingCable GlandsElectrical Components
Trailer Parts & ServicesTrailersTransport EquipmentTrailer Transport Service
Transport EquipmentTransport ServicesTransport AgentsLorry Transport
OilsCrop ProtectionGreasesIndustrial Lubricants
Fuel OilsOilsOrganic ChemicalsChemicals By Name
OilsScrew Machine Products
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You missed it This great deal for Burger Joint is over. But don't despair, we've got more great deals every day.
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$50 or $100 Toward Lunch or Dinner
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Burger Joint
$10 to Spend on Online Ordering in SoMa
With LivingSocial's Takeout & Delivery, online ordering is easy: Browse menus from local restaurants, place your order on our platform, and pay with your LivingSocial account—no need to pick up the phone or scramble to find cash!
Today, pay $5 and you'll get $10 to spend on online food and drink orders from Burger Joint. Sure, cheese can make a burger pop, but this franchise has something else that makes its patties that much better: environmentally responsible, farm-raised beef. Land a flame-touched patty propped up on a toasted bun and topped with all the fixins; or snap up alternatives, like the Philly cheesesteak and the chicken-charged Caesar salad. Regardless of your main, piping hot fries are the ultimate accompaniment.
PAID VALUE EXPIRES ON February 27, 2022
PROMOTIONAL VALUE EXPIRES ON May 15, 2013


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This popular udon restaurant is located near the Heian Shrine. (If you are walking there, it is very scenic to walk along the canal rather than the main road). Unfortunately, the only day we could fit it in was a Saturday. We knew it would be busy so we showed up 15 minutes before opening time, only to discover that there was already a significant line in front. We waited for about 1 hour 15 minutes before we were seated. (It was very hot that day, I assume the line might be longer when the weather is more pleasant).
We got the cold udon with chicken tempura, which was amazing. We liked it so much we ordered extra noodles and then extra chicken tempura. We also got a hot Kyoto-style curry udon, which we didn't like as much. They do have an English menu. The people who work there are very friendly and helpful. Although the line was long, they came out to bring us cold tea and to take our order in advance. We decided the lunch was worth the long wait...
Updated 4 months ago | 3
Updated 1 month ago | 11
Updated 4 months ago | 0
Updated 4 days ago | 2
Updated 5 months ago | 0


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Doret Vermeulen <email@example.com> wrote: To all the ferny people around the world.
I got a list of cheilanthes species that can be found in Namibia. The only
problem is I am not able to find any photo's or sketches of these plants. Good Morning Doret...
well I did some random checking on www.google.com and came up with photos in the images section for about 4 out of every 5 species you list...so might I suggest you check that out..
.secondly are there any second hand book stores nearby? they might have a book or two in the Botany or Wildflower section
last resort..go to your local university and see if they've an extensive library that you could be able to check into...who knows maybe you'll sigh up for some classes while your there...
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To embed, copy and paste the code into your website or blog:
"Hello Jake, I hate to tell you this but we can't ship your order this week. One of our key suppliers is holding us up."
That's a customer phone call you never want to make. If you are like most companies, a significant supply chain interruption could wreak havoc on your operations. Lines would be shut down, customer orders delayed or terminated, and profits stymied. How likely is it that your business is vulnerable to a serious interruption in supply? According to a recent PricewaterhouseCoopers survey of family-owned businesses, approximately 70 percent do not survive past the first generation, so this type of disruption could be imminent if your supply chain includes such businesses.
Significant OEM's in our region are beginning to focus on the topic of supplier succession planning. Quality and delivery are critical, but years of work to optimize the chain can disappear overnight if a key supplier is unprepared for the retirement, death or disability of its owner. All too often unexpected change results in the close of the business. Reducing the risk of this type of disruption in your supply chain may not be something you thought was in your control. But there are steps you can take to identify the companies in your supply chain that may pose a risk.
The first step is to have thoughtful discussion with each of your key suppliers to understand where they are in the process of planning the transition of their business. Questions that will facilitate your discussion include:
Does the owner have a current business succession plan in place? If not, will he/she agree to put one in place within an agreed upon time frame? You want to know that the supplier has governing documents that are aligned with its business succession plan. For example, who are the company's planned future owners? Do the governing documents clearly state how the future owners will gain ownership interest in the company? If there are multiple owners, is a buy-sell agreement in place? Does the buy-sell agreement suggest how the company will be valued upon the death of an owner?
Does the owner of the company have an estate plan in place? An estate plan typically consists of a Will, Trust Agreement, Durable Power of Attorney and a Designation of Patient Advocate and Living Will. The fiduciaries named in the estate planning documents (i.e., the Personal Representative, Trustee, Agent and Patient Advocate) will have the legal authority to act on the owner's behalf in the event of an incapacity or death. Without these documents in place, a conservatorship and/or guardianship must be obtained through the local Probate Court, which will likely lengthen, or make permanent, the disruption of supply to your business.
Is the owner's estate plan coordinated with the business succession plan? Fiduciaries named in the owner's estate plan to act on behalf of the company should be the same individual(s) the owner has internally designated to run the company in his or her absence. Without such coordination, a company may end up with a fiduciary that has no prior experience running the company. This can lead to devastating effects for the supplier and, as a result, your business.
How does the company mentor and train its designated future leader(s)? Preparing a future leader may be one of the most important steps to creating a successful transition of management on an owner's death, disability or retirement. Yet, we find this step is often overlooked. It is never too early to start developing and nurturing future leaders to ensure they are ready to step into the owner's shoes at a moment's notice.
Has the business succession plan been communicated to the management of the company? The manner in which a succession plan is communicated will impact the outcome of the succession plan, sometimes more than the succession plan itself. The PricewaterhouseCoopers survey of family-owned businesses states: "A clearly communicated plan signals that the company is here to stay." This is particularly true when communicating a succession plan to the management (and potential future leaders) of a company. It is imperative to gain the confidence and support of the management team in relation to the succession plan. Otherwise, the company risks driving out important nonfamily members after the departure of an owner.
Is there sufficient liquidity to financially support the owner's family, pay any necessary estate or income tax obligations, and secure the future of the company? Often times, an owner's wealth is tied up in his or her company. For that reason, it is crucial to understand whether there will be enough liquidity in the company to continue to operate after tax and family obligations are met. You want to know the owner has thought this through and has a plan in place.
Subsequent steps to take with your supplier will depend on their answers to the foregoing questions. However, if your key supplier answers "no" to most of these questions and exhibits no interest in putting a succession plan in place, you may want to consider vetting additional suppliers to protect the on-going operation of your business.
Switching focus from your suppliers to your customers, consider this: If your key customer(s) asked you the above questions, would you be prepared, or would you pose a risk to them? Given the growing interest in this area, you may find that having a succession plan in place gives your business a competitive advantage.
All business owners must exit the business at some point. The goal of business succession planning is to have as little disruption to the business (and family) as possible in the event of an owner's incapacity or death. Put your own plan in place, and start the discussion with your key suppliers now.
This article originally appeared in the Grand Rapids Business Journal.
See more »
DISCLAIMER: Because of the generality of this update, the information provided herein may not be applicable in all situations and should not be acted upon without specific legal advice based on particular situations.
© Varnum LLP
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Waterside Holiday Apartments
No prices found through our partners. Please contact the business directly or check some of our recommended alternatives.
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TripAdvisor Reviews Waterside Holiday Apartments Manly
Travel Blogs from Manly
Pancakes and a city walk
... we booked was open dated, so we can do it whenever we want. We spent around $2,700AUD (about £1,300), which got us - a 3 month unlimited greyhound bus pass, 22 nights open dated accommodation in X Base or Nomad hostels, 5 days surf camp at Spot X (including 2 lessons a day, all food, accommodation, wetsuit and surfboard hire, and activities), a 3 day 4X4 self drive on Fraser Island (including all food, accommodation for 2 nights and accommodation for 1 ...
72-96 hours in Sydney
... up town walk to Martin place, check out Sydney tower aka Centrepoint tower for amazing views.
Walk over to Town hall & check out QVB building itself and its' shops, amble up to Hyde park and St. James's church b1819 oldest church in Australia & convict designed - features in TV alternative travel shows - have a spot of lunch in World Square perhaps.
Afternoon in ...
Spit Bridge to Manly Coastal Walk
... for a quick bite...
Our tiring legs were given a thorough massage when we got back on the 30 minute ferry ride back to Circular Quay from Manly Wharf.. With the chill winds picking up, and the views of the harbour and the pacific ocean sliding by, we were finally welcome by the majestic Sydney Opera House and the spectacular skyline of "the city".... with the sun just setting behind the Harbour Bridge... a glorious end to an amazing day..
Hope you had a nice walk ...
I'm Still In Love With Manly
... all still there. Seeing as though we had had a small lunch (for us) we decided to treat ourselves to an ice cream - we were at the beach after all! $6 bought us possibly the biggest ice cream I have ever seen. The free toppings you did yourself meant we both went to town, mainly by accident, on sprinkles, hundreds and thousands, and sauces. We sat on the steps down to the beach to tackle them properly and it took me a good half an hour to finish it all. Safe to say I ...
An amazing week in Sydney
... harbour where we could see the bridge, the opera house and the amazing city skyline. We admired the amazing view of the harbour enjoying an ice-cream each in the sunshine. The perfect introduction to Sydney. Having not seen each other for months the three of us, despite still not having any sleep, decided we should celebrate the first night together with a few drinks. Conveniently, our hostel is connected to a decent bar so we walked next door and enjoyed a ...


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Owner Financing Homes in Osceola, IA
|6 Listings Found
of CRP with an annual income of $11,527; contracts expire in 2022 and 2025. Mature timbered draw
Osceola, IA, 50213Details »
Income producing pasture land for sale in Derby, Iowa. Approx $6,000 in CRP income, plus additional
Derby, IA, 50068Details »
This 100+/- acre property is located 45 minutes from West Des Moines in Madison County Iowa, just south of Winterset. The farm has...
Lorimor, IA, 50149Details »
been enrolled into CRP in 2016 and will have ten full years of payments on the contract
Thayer, IA, 50149Details »
and electric at the road Owner will consider a trade or contract sale Directions Winterset South four way stop
Winterset, IA, 50273Details »
to Creston has beautiful bird cover, and the owner even has images of a large buck that calls this farm home
Afton, IA, 50830Details »
RentUntilYouOwn.com is the #1 provider of Osceola, Iowa owner financing homes listings.
Our goal is to offer the highest quality results, along with helpful Osceola resources and support. We understand that finding genuine owner financing homes in Osceola can be very difficult. Even more challenging is trying to search Osceola, IA listings for free.
After discovering how difficult it was for Osceola buyers and sellers searching online, RentUntilYouOwn.com has become dedicated to providing users with the most current, accurate, and detailed listings in Osceola, Iowa.
If you have any questions or suggestions for improving our site, please contact us here.
Trouble Finding Local Owner Financing Homes Listings?
If the initial results in Osceola, Iowa did not provide any listings of interest, or you just want more selections, click any of the blue tabs just above the search results for more.
Thanks for visiting and good luck!


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46th Street Bliss Stop - Summer Sunset
Thanks to the Queens Ledger for their profile of my photogaphy and for featuring this pic: queensledger.com/view/full_story/17956386/article-Shots-o...
And Thanks to Gothamist for featuring this on their site.
THanks to the Travel Blog for featuring my pic!
10,686 views
67 faves
46 comments
Taken on July 30, 2009


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90 Millburn Ave., Suite 201 | Millburn NJ 07041 (Exit 142b off GS Parkway)
521 Newman Springs Road, Suite 21 | Lincroft, NJ (Exit 109 off GS Parkway)
494 Route 17 North, Suite 2 | Paramus NJ (Exit 163 off GS Parkway)
We need blood work prior to any patient stating chelation therapy.
Chelation Therapy Is Still Considered Experimental for cardiovascular issues and Patients Must Understand Risks and Alternatives To Such Treatment Prior to Starting. Consult your primary care physician prior to starting Chelation Therapy.
We use Chelation therapy (on label) to remove trace amounts of lead and other toxic metals (off label). Also beware that there are no definitive tests to determine the exact levels of toxic metals in your system. Blood, hair, fecal, radiographic, or challenge urine toxicity testing is only a general determinant that toxic metals are in your system; as metals settle into different organs depending on age, metal and nutrional status. We utilize challenge urine toxicity testing as a general indicator of toxic metals. There are safe levels of toxic metals according to government standards; but in Preventive Medicine the ideal is to eliminate completely ALL toxic metals.
Lyn Patrick ND.mp3
Jeffery Morrison MD.mp3
Rita Ellithorpe MD.mp3
Richard Linchitz MD.mp3
Eric Braverman MD.mp3
Toxic Metals Brochure
The Case for Intravenous EDTA Chelation Therapy
Scientific Rationale for EDTA Chelation Therapy
A Summary of EDTA Chelation Clinical Research
Current Status of EDTA Chelation Therapy in Occlusive Arterial Disease
by Linus Pauling, PhD
For more than twenty years I have devoted most of my time to research and education in the fields of nutrition and preventive medicine. I have written and lectured extensively about simple, safe and inexpensive measures to improve the length and quality of life. In my recent book, How to Live Longer and Feel Better, I covered that subject at length. EDTA chelation therapy fits in well with my views on health care.
EDTA is not normally present in the human body and is therefore, by definition, not an Orthomolecular substance. Chelation, however, is far safer and much less expensive than surgical treatments for atherosclerosis.
Heavy Metal Detoxification NJ
"Approximately 250,000 U.S. children aged 1-5 years have blood lead levels greater than 10 micrograms of lead per deciliter of blood, the level at which CDC recommends public health actions be initiated. Lead poisoning can affect nearly every system in the body. Because lead poisoning often occurs with no obvious symptoms, it frequently goes unrecognized."
Toxic Metals Brochure
Heavy Metals are shown to cause disease. Precise levels that are toxic to one person are benign to another. When evaluating toxicity one should consider the patient's overall health and what combination of toxicities their specific patient can handle. If the CDC and EPA issues a statement or policy stating that the toxic level is10 micrograms per deciliter of lead; but what is your child also has low level mercury exposure and happens to be already immuno-compromised with strep throat? The Cleansing Clinic believes that ANY poison is too much poison.
The Cleansing Clinic utilizes blood, hair, urine and fecal testing to determine heavy metal toxicity and works with patients to determine a strategy to promote optimum health. The most common metals we see in patients are lead, mercury, cadmium and aluminum. Mercury is chemically similar selenium; Lead is chemically similar calcium; Cadmium is chemically similar to zinc and Aluminum is chemically similar to magnesium. The metals are so chemically similar to substances your body NEEDS to function that your body is tricked into absorbing them. Once inside, these metals are trapped and begin a cascade of devastating effects; most of which are just coming into focus.
Exposure to mercury occurs from breathing contaminated air, ingesting contaminated water and food, and having dental and medical treatments.
The nervous system is very sensitive to all forms of mercury. Methylmercury and metallic mercury vapors are more harmful than other forms, because more mercury in these forms reaches the brain. Exposure to high levels of metallic, inorganic, or organic mercury can permanently damage the brain, kidneys, and developing fetus. Effects on brain functioning may result in irritability, shyness, tremors, changes in vision or hearing, and memory problems.
Short-term exposure to high levels of mercury may cause effects including lung damage, nausea, vomiting, diarrhea, increases in blood pressure or heart rate, skin rashes, and eye irritation.


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Banana Sundae – January 1, 2016 FULL HD REPLAY
Banana Sundae (formerly Banana Split) is a Filipino comedy gag show broadcast on ABS-CBN every Sunday after ASAP and before Kapamilya Mega Blockbusters.
Featuring Angelica Panganiban, Jason Gainza, and John Prats, with Pokwang, JC De Vera, Jessy Mendiola, Pooh, Zanjoe Marudo and Pinoy Big Brother: Teen Clash of 2010 2nd Big Placer Ryan Bang.
Banana Split is the spiritual successor to the Goin' Bananas series which included Edgar Mortiz, Christopher de Leon, and the late Jay Ilagan and Johnny Delgado.
Banana Split Extra Scoop ended on November 7, 2015 after its four-year run to give way to Banana Sundae that premiered on November 15, 2015 and move to Sunday depicting its program's name.


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By Steve Godwin, Published Mar. 11, 2012, Updated Oct. 18, 2013 at 2:46 PM UTC
In this video we interview Competitor Of The Year Meb Keflezighi at the 2012 Endurance Live Awards.
MORE VIDEO–Female Runner Of The Year: Jenny Simpson
Start your FREE subscription to Competitor Digital today!
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News By Tag
* Reset Branding
* Branding Expert
* Toronto Branding Agency
* Toronto Branding Company
* John Miziolek
* Brand Strategy
* More Tags...
Industry News
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Industry News
Branding Expert John Miziolek Designated as Expert Blogger For FastCompany.com
John Miziolek, up and coming branding star, will be featured as an expert blogger on FastCompany.com with his blog series, "John Miziolek: Branding the Future."
John Miziolek has been seen in USA Today, CNBC, Yahoo! Finance, MarketWatch, Morningstar and CBS MoneyWatch, among others. He is one of the premiere strategic branding professionals who are making waves in the cutthroat world of design agencies. He specializes in brand strategy, consumer insights and name generation. His experience in building and revitalizing brands spans every category of consumer packaged goods and corporate development. As one of the co-founders of Reset Branding, Miziolek has turned the traditional design firm model upside down to create an innovative agency that reaches out to clients all over the world.
With offices in Toronto, New York and Chicago, Reset Branding specializes in strategy for both consumer and business-to-
According to their website, "Fast Company sets the agenda, charting the evolution of business through a unique focus on the most creative individuals sparking change in the marketplace. By uncovering best and 'next' practices, the magazine and website help a new breed of leader work smarter and more effectively. Fast Company empowers innovators to challenge convention and create the future of business."
John Miziolek's first blog post was titled "How Dove Reinvented Its Brand For Men." You can read the full post at http://www.fastcompany.com/
To learn more about John Miziolek and Reset Branding, please visit http://www.ResetBranding.com
# # #
The Dicks and Nanton Branding Agency helps businesses brand themselves online by elevating their expert status through the use of television, radio and feature publications.
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