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Harmony Collection Freshadama Freshwater Pearl & Diamond Pendant
Product Description
This unique pendant features a single Freshadama quality Freshwater pearl. The diamond setting is beautifully crafted from solid 14-karat gold, which sparkles with a VS1-G, 0.05 ct. round-cut diamond resting right above the pearl. The pendant is available with your choice of a white, pink/peach or lavender pearl, set on a 14-karat white, yellow, or rose gold setting. It is also available with no chain or with your choice of matching box chain.
Technical Specifications
- Pearl Origin
- China
- Pearl Body Color
- White
- Pearl Quality
- Freshadama
- Pearl Shape
- Round
- Diamond Weight
- 0.02 carats
- Diamond Clarity
- Diamond Color
Shipping Methods & Rates
- 5-7 Business Days
- Free
- 3 Day
- $15.00 (3-4 Business Days)
- 2 Day
- $18.00 (2-3 Business Days)
- Overnight
- $25.00 (1-2 Business Days)
- Saturday Delivery
- $50.00 (cutoff Noon Friday)
Our Promise to You
We guarantee complete satisfaction on all of our products.
We guarantee top-quality customer service from our expertly-trained and respectful team.
We guarantee your pearls will be hand-selected and individually inspected to ensure our highest quality standards.
90 Day Money-Back Guarantee
Customer Guarantee: We guarantee complete satisfaction on all our products. If you are not satisfied for any reason, please return the item(s) within 90 days for a complete refund - no questions asked.


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Written on: 15/03/2013
This order was excellent from the time I created it on the website, the quick processing, to the delivery four days later. The tri canvas turned out exactly as I expected in terms of image placement,and the quality of the print on the canvas is spectacular. I was very pleased with how easy the website was to use to create my canvas, and the resulting quality exceeded my expectations. It would have been nice if the final preview image could be viewed larger. But if that's my only complaint, you should be patting yourself on the back. What great service and a great company to work with! Thank you very much!
As rated by our community of reviewers
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Written by Hawks18

subset: commoncrawl


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IT MAY be considered an old fashioned material by some but these award-winning designers have shown that timber can be modern and amazing.
The winners of the Intergrain Timber Vision awards announced this morning include a mixed-use project which looks more like a work of art than a building.
The multipurpose Nishi building in Canberra won the Best Commercial Interior in the awards.
It was designed by March Studio. The building has residential and commercial space plus retail and hotel zones.
The judges said March Studio had managed to create a space which encouraged inhabitants and guests to linger.
It made "spectacular'' use of timber as not just art but also architecture.
Thousands of strategically placed recycled lengths of timber are artistically hung within the building.
The awards aim to recognise and celebrate the valuable role timber plays in Australian architecture and design.
More than 100 entries were received for the awards this year with four major winners announced.
Intergrain Brand Manager Trade, Amanda Chalmers, said the calibre of submissions and number of entries had reached a new high.
"Many of our entries pushed the boundaries with their innovative use of timber this year,'' she said.
The Commons commercial space, in Brunswick Victoria, designed by Breathe Architecture, won Best Commercial Exterior.
Judges said it was a great blend of design and functionality.
They said the "smart design and natural timber facade'' was visually pleasing and softened the grittiness of its industrial surrounds.
The two residential award categories were recognised for showing how timber could be used as an alternative to other materials.
Stonewood, by Breathe Architecture, won the title of Best Residential Exterior.
The project took its inspiration from a 1850s Georgian cottage. It uses timber to connect the interior and exterior in the Melbourne home.
"Overall the home is viewed as warm, handsome and distinct,'' the judges said.
The Best Residential Interior award went to Lilyfield Warehouse designed by Virginia Kerridge Architects.
Judges said the warehouse in Lilyfield, New South Wales, displayed a creative timber adaptation to an existing industrial warehouse.
"Using recycled timber and materials with natural weathering properties, the re-purposed residence presents a cohesive blend between the existing structure and new design.''


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By Isabelle Kassam
Every parent wants the best for their child financially, and to put aside as much as possible to give them a secure future.
But for parents of the UK's 770,000 children with disabilities, decisions can be far tougher than simply working out how much they can afford to tuck away in a building society each month.
The Conservative leader David Cameron, who has a son with cerebral palsy, last week highlighted one of the major causes of frustration for parents of children with learning or physical disabilities - the complexity of the benefits system. And as well as negotiating the benefits maze, they may also find that they have to give up work to care for their child. Those who continue to work outside the home will probably have to fund highly skilled and thus expensive childcare.
The medical problems involved vary hugely, but in many cases special equipment will have to be purchased. Normal baby kit such as high chairs or buggies may not be suitable and, as a child grows, wheelchair ramps, stair lifts and other adaptations may be needed at home.
The cost of bringing up a disabled child is estimated by charities to be three times higher than providing for a healthy child.
"Many parents say that the best way to find out what they are entitled to is to meet other parents who have children with the same condition as theirs," says Louise Moffat of Contact a Family. "Meeting someone who is going through the same problems you or who has already manoeuvred their way through them is often a massive relief."
Contact a Family is a charity that puts parents whose children have the same disabilities in touch with each other, allowing them to set up their own informal support groups.
It also advises on benefits and tax credits that are available to disabled youngsters and their families. As Mr Cameron pointed out, each benefit or tax credit comes with its own qualification rules and its own set of forms. Parents have to work out what they might be entitled to and then make their claims as quickly as possible - many cannot be backdated.
Parents of disabled children often have lower than average incomes and higher expenditure. A Cabinet Office review last year found that 55 per cent of disabled children grow up in, or at the margins of, poverty.
Not all will be reliant on their parents for help in adulthood, but the biggest issue for parents of mentally or physically impaired children is what will happen after their own deaths.
Expecting a disabled child to be able to manage an inheritance, or relying on a sibling to care for a disabled brother or sister, is a mistake that many parents make, according to Aarti Puri, the in-house wills and trusts solicitor for the charity Mencap.
"People often think their child will be fine if they leave them a property," says Ms Puri, who puts families of learning-disabled children in touch with local solicitors to help them make a will. "But if there is no other cash, how will the child maintain the property? And if inheritance tax is due on the estate, the child may be forced to sell, which is not what the parents intended."
Carol Ellis, 42, gave up her job as a civil servant 16 years ago, after her son Thomas was born.
He suffers from unbalanced chromosome trans-locations, a genetic condition that has left him severely mentally and physically impaired.
"Although Thomas can crawl, and can appreciate coloured lights and music, he cannot communicate or look after himself in any way," Carol explains. "I went back to work when he was a baby but there were so many hospital appointments to attend. It's hard for an employer to be understanding in those circumstances."
Her husband Kevin, 45, is also a civil servant and the couple, from Bristol, have a daughter Lauren, who is 11.
"Since Thomas turned 16 he has been able to claim benefits in his own right and we are about £300 a month better off as a family," says Carol.
The Ellises are now planning to move to a new home and to build an extension so that Thomas can have his own bathroom and a sensory space where he can enjoy lights and sounds.
They are taking on a bigger mortgage and still worry about one-off expenses. For example, they had to buy Thomas a specially adapted bed, which cost around £1,000.
Financial Help: Unravelling the benefits maze: what to claim, when to claim it
The main benefit for disabled children is the Disability Living Allowance, which pays up to a maximum of £105.70 a week. It isn't means tested, but the amount a family receives depends on how much care a child needs and on their level of mobility.
Carer's Allowance is available to parents who care for a disabled child for at least 35 hours a week and earn less than £84 a week (after caring expenses). Low-income families can also apply for income support, child tax credit, housing benefit and council tax benefit.
Community care grants can help families with disabled children to buy items such as clothing or bedding.
When they turn 16, young people who are disabled can claim benefits in their own right, in addition to those received by the family. If a child is unable to handle their own affairs, the benefits will usually be paid to a parent.
Looking for credit card or current account deals? Search hereReuse content


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Stunning midi poster featuring the work of award winning photographer David Noton. This poster depicts the natural limestone arch in Dorset England known as Durdle Door. A truly amazing piece of natural architecture.
Thank you for visiting David Noton Durdle Door - Midi Poster - 30.5cm x 91.5cm on bananacorner.co.uk
We bring the products from many websites to one website for you to search, save and compare.


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To see a 7 page preview, click HERE
you can also order a copy from my site HERE
I'll be at the Indie Spinner Rack table at the New York Comic Con with Julia Wertz this Saturday from 4-7 if you're there and want to swing by. Also I'll be at the Stumptown Comics Festival in Portland in 2 weeks. I'll be doing a reading art Guapo Comics on the 25th along with Julia, Austin English, Liz Baille and many others. Come by if you live in Portland!
Also, I was somehow nominated for the Maisie Kukoc Award for Comics Inspiration along with Liz Baille, Alex Holden, Rina Ayuyang, Jon Chadurjian and David King. You should vote if you read minicomics. You certainly don't have to vote for my comic, but DO vote! These other guys are all super talented artists and I'm flattered to be nominated with them.
To vote, email Jesse Reklaw for a ballot at firstname.lastname@example.com.
Tags: israel comics kukoc


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Macadamia Sunrise Herbal Tea-Caffeine Free
$103.99 Ships free Australia wideBack to top
Macadamia Sunrise Herbal Tea-Caffeine Free
by Welcome to the IslandsIn Stock
$103.99 Ships free Australia wide
Delivery: Free shipping anywhere in Australia Delivery within 6-12 working days
(Shipments to NT and rural WA may take longer) Free SMS notifications
(Australian mobile numbers only)
(Shipments to NT and rural WA may take longer) Free SMS notifications
(Australian mobile numbers only)
More options: Ask a question about this product More products by this brand
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Product details:
Island Plantations premium teas are carefully selected from growers and handcrafted into delicious, tropical treats. Savor the taste of paradise. Each beautiful, collectible tin contains 12 tea bags and measures approximately 3⅝" L x 3⅝" W x 4-7/16" H with lid.
Brand: Welcome to the Islands
Product ID: 1117204366870416
Product Dimensions: 9.3cm x 9.2cm x 12.7cm
- Free delivery Australia wide
- 24/7 parcel tracking
- Customer support
- Full factory warranty
- Easy returns
- Secure checkout
Information above was provided by the manufacturer or local distributor.
Please check the packaging and read instructions prior to using the product.
Found an error with this listing? Let us know.


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Rosemary Chicken With White Beans
|Italian seasoned bread crumbs
|3 Tablespoon
|Minced fresh rosemary
|1 1⁄2 Tablespoon, divided
|1⁄2 Teaspoon, divided
|Freshly ground black pepper
|1⁄2 Teaspoon, divided
|Egg white
|1 Large, lightly beaten
|1 Teaspoon
|Skinless boneless chicken breast halves
|24 Ounce (4 Pieces, 6 Ounce Each)
|Olive oil
|2 Teaspoon
|3 Clove (15 gm), minced
|Canned navy beans
|16 Ounce, rinsed and drained (1 Can)
|Chopped fresh tomatoes
|1 1⁄2 Cup (24 tbs), chopped (2 Medium Size)
1. Combine breadcrumbs, 1 1/2 teaspoons rosemary, 1/4 teaspoon salt, and 1/4 teaspoon pepper in a shallow dish.
2. Combine egg white and water in a shallow dish.
3. Place each chicken breast in egg white mixture, allowing excess to drip back into dish. Dredge chicken in breadcrumb mixture.
4. Heat oil in a large nonstick skillet over medium heat. Add chicken; cook 6 to 7 minutes on each side or until chicken is done. Transfer chicken to a plate. Set aside and keep warm.
5. Add garlic to pan; cook, stirring constantly, 30 seconds. Stir in beans, tomato, 1 tablespoon rosemary, 1/4 teaspoon salt, and 1/4 teaspoon pepper. Cook over medium heat 2 minutes or until thoroughly heated.
Rate It
Nutrition Rank
Nutrition Facts
Serving size: Complete recipe
Calories 2645 Calories from Fat 263
% Daily Value*
Total Fat 30 g45.7%
Saturated Fat 5.1 g25.7%
Trans Fat 0.2 g
Cholesterol 394.6 mg131.5%
Sodium 2648.1 mg110.3%
Total Carbohydrates 330 g109.9%
Dietary Fiber 119.7 g478.7%
Sugars 28.2 g
Protein 271 g541.4%
Vitamin A 61.2% Vitamin C 87.6%
Calcium 97.6% Iron 192.7%
*Based on a 2000 Calorie diet


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Mansions on Pulteney
Our website has moved to
Please click the link to view our new page showcasing our 3 great locations.
Welcome to Mansions on Pulteney 08 8232 0033
Reception Hours -: Mon-Fri 8.00am - 8.00pm, Sat- Sun and Public Holidays 8am-6.00pm, Xmas Day Closed (Arrival by prior arrangement)
Email: email@example.com
Mansions on Pulteney provides 3.5 star serviced apartments in the heart of Adelaide CBD at 21 Pulteney Street between Rundle Mall & North Terrace.
Perfectly located near Adelaide's shopping, restaurant, cultural and university precincts MP provides the best possible access to these venues for any visitor to Adelaide. Other attractions within easy walking distance include the River Torrens, the Adelaide Zoo, the Royal Botanic Gardens, the Festival Theatre, the Convention Centre and of course the famous Adelaide Oval. The ideal location for your stay in Adelaide – whether you are from overseas, interstate or just 'out-of-town'.
Mansions on Pulteney offers you every convenience the heritage building boasts many of its original 1912 features with high ceilings and spacious rooms. Our studio and one bedroom apartments offer all the comforts of home including fully equipped kitchens, reverse cycle air conditioning, wireless internet access, LCD TV's, opening windows and balconies. With all this to offer MP is the perfect destination for the corporate traveller and holidaymaker alike.
Car parking with 24 hour unlimited access is available directly across the road at just $18 per night (Height restriction 2.1m)
Complimentary Wifi
- 71 reviews of Mansions on Pulteney in Adelaide


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If you are stupid enough to vote for Hillary Clinton, then you better get ready to pay up in taxes.
Category: Taxes
Hillary Clinton would raise taxes by $1 trillion
As Hillary Clinton continues to show desperation and out communist Bernie Sanders, now she wants a TRILLION in tax increases
Getting a Christmas tree? There's a tax for that
Getting a Christmas tree? Get ready to pay a USDA tax on any fresh cut tree you decide to buy.
Why the IRS insists you pay taxes on time
Want to know why the IRS insists that you pay your taxes on time (unless you are a Democrat)? 1.
Obama's IRS ObamaCARE tax called Shared Responsibility Payment
When you file your taxes next year, you will notice a new tax called the Shared Responsibility Payment. Obama's IRS
House of Cards may leave Maryland because of taxes
House of Cards is a popular Netflix with the upside down flag. I don't watch it, but know many who
New taxes in ObamaCARE coming in 2014
As if ObamaCARE itself isn't bad enough, get ready for some brand new taxes in less than a week as
ObamaCARE Health Insurance Tax set over Thanksgiving
The ObamaCARE Health Insurance tax was quietly finalized this past week during the Thanksgiving Holiday. The ObamaCARE Health Insurance Tax
New ObamaCARE tax of 9.5 percent in Michigan
A new ObamaCARE tax of 9.5% has been revealed by Blue Cross / Blue Shield of Michigan. They call it
Are you ready for the ObamaCARE wedding tax?
Get ready for the ObamaCARE wedding tax. If you are a married couple, especially with no kids, and are getting


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Description from West Elm
Counter style. The Design Workshop Metal Top Bar + Counter are conveniently fitted with wheels for easy mobility. Made in the USA, the blackened-steel top and rolling cart and solid wood shelves create sturdy, versatile heirloom pieces.
- Metal components made of solid steel milled in South Carolina and Kentucky, with a Blackened finish.
- Wood components made of solid oak harvested from the mountains of North Carolina and Tennessee, in a Natural Lime finish.
- Assembled upon arrival via In-Home Delivery.
- Wipe clean.
- Made in the USA.
Prices range from $2,299.00 to $2,399.00
$2299.00 USD Buy from West Elm


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Comfort Inn & Suites Red Deer
No prices found through our partners. Please contact the business directly or check some of our recommended alternatives.
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Annnnnd it Begins....
... a good and bad place. The simplest moments and smallest gestures have made me cry tears of gratitude and happiness. I've swam in more bodies of water than I could name, said hello in more languages than I could list and still there is so much more I want to explore and learn. Some of the times I have felt most at peace in my life have been when I am all by myself; a foreigner in another land totally divided by looks, beliefs, religion, language. ...
... day. Addie bought little, uncleaned ones for us so guess what she did this morning! After an evening of heartburn brought on by who knows what, I was not interested in shellfish this morning.
Found the uncompromised ATM in town and got some more lempiras. The currency is taking time to know. Their biggest bill is 500 limps which is $25 so you can imagine the wad. Brian told me yesterday that there is stuff smaller than the 1 limp which is 5 ...
Like a good book, I can't put this day back
... time we went to Lima. Travelling was exhausting and stressful but exciting and I'll always remember how excited I was in the Toronto airport... I spent so much money on food.
Getting to Lacombe and meeting our host families was super exciting. It was such a change being with people who spoke english, and as much as I love Peruvians... the Canadian families are way more easy going. It was so exciting being able to cook or bake whenever I wanted. I loved showing Canada to ...
Good is better than perfect
... brother and I don't know how I would survive here without him. He is loud and obnoxious and ridiculous sometimes, but he can also be so sweet and protective it melts my heart. When he gets rid of that stupid, annoying, wall he has up, and you get to see how intelligent and compassionate he actually is, its really special. I really hope that we stay in touch after the program, but Ottawa is close to Quebec so that won't be too difficult!
Tonight there ...
A wonderful prayer from total strangers.
... could add them to my blog. What a way to start my trip. Their names are Elaine and Terry. The cute 8 yr old poodle is called Sparky. Interesting name seeing that my nickname is Sparky to a lot of people. Another interesting note is that the couple were actually heading to Wendy's to eat and decided to go to MacDonald's. That was a really cool experience. God does some really amazing things doesn't He!! See picture below of the ...


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This summer so your skin a favor by practicing safe beauty. Our cold pressed, organic barbary fig seed oil heals, repairs and protects. Don't be in or out of the sun without this gentle antioxidant super oil. NEW from La Bella Figura and finally in the USA!
Practice Safe Beauty
Posted on June 01 2012
1 comment
Jozef: July 08, 2012
I would love to sell organic buaety products to people and be able to give them a catalog that they can look from just like how other people sell AVON or Mary Kay. I have looked on the internet and found something that sells make-up for over $50 for foundation. I have found at Walmart that they can sell organic make-up for $6.00 foundation. Any help would be appreciated!!
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Apple Watch Hermès leather bands are now available
If the gold Apple Watch isn't your style but you still want to spend a ton of cash, look no further.
TAG Heuer's first smartwatch gets a $400 price bump
Remember when TAG Heuer's Android smartwatch was only gonna cost $1,400. Good times, man, good times.
A closer look at that fancy new Hermes Apple Watch band
Apple's Watch line also received some updates today -- including some fancy options from French outfit Hermes.
Apple reveals new Watch colors and a leather Hermes band
On top of the Hermes model, you can get rose gold aluminum and 'Product Red' stainless steel.
MIT's robot borrows quick reflexes from a human pilot
The Hermes humanoid robot can move at the same time as its human controller.
Leica teases our wallets with $50,000 Edition Hermès M9-P, $1,000 scarf sold separately
If you've ever wondered if designer names alone can send a product's price tag through the roof, t...
GameBoy Advance Phone caught in the wild (by the guy who built it)
Perhaps if there was some sort of Brundlefly-style gadget mix-up five years ago, the outcome would...
Leica M7 Hermes unboxed, photographed, then promptly re-boxed
So what's it like to be one of 200 people in the world to own the $12,950 Leica M7 Hermes? Quite go...
HTC announces TyTN II / Kaiser for Europe
Well it's not quite as good as, say, AT&T informing us that we can walk down the block and pick...


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All the events and news that happen around the world can have a great impact on the stock market. Very often, if a war breaks out or political problems arise the stock market will take a plunge. The saying of "buy on the sound of cannons, sell on the sound of trumpets" suggests that the start of, or the continuance of, a war is a good time to invest in the stock market, while the end of a war is a good time to sell. The saying was coined in 1810, and is attributed to London financier Nathan Rothschild.
The idea behind this phrase is that during times of war there is a considerable amount of uncertainty and panic in the markets, which leads to selling. This selling pushes down the value of stocks leading to lower valuations and making it an attractive time to buy even if there is a war ("buy on the sound of cannons"). In contrast, when the war ends and uncertainty and the risks of war are removed from the market, people start to buy. This increase in buying causes stock prices to rise again - leading those just-purchased-at-low-prices stocks to higher valuations, making this an attractive time to sell ("sell on the sound of trumpets").
The term also is used in a similar manner to the phrase, "buy on bad news, and sell on good news." This constant theme in the financial market simply suggests that the market often overacts to both good news and bad news, which provides investment opportunities if you are watching carefully.
For further reading, see When Fear And Greed Take Overand Taking A Chance On Behavioral Finance.
How did World War II impact European GDP?Understand the effect of World War II on the European gross domestic product and what foreign and domestic factors influenced ... Read Answer >>
Why does the IRS withhold income taxes from employee paychecks?In the midst of WWII, the U.S. government ran into trouble funding the war effort. The problem did not originate from citizens ... Read Answer >>
Why do stock prices change following news reports?Stock prices move up and down every minute due to fluctuations in supply and demand. If more people want to buy a particular ... Read Answer >>
What was the Marshall Plan?The Marshall Plan was a U.S.-sponsored program implemented following the second world war to aid European countries that ... Read Answer >>
How long has the U.S. run fiscal deficits?Read about the history of deficit spending in the United States, dating back to 1789, and learn about then-Treasury of the ... Read Answer >>
Government Debt: From Billions To TrillionsThe national debt has been growing in leaps and bounds. Find out why.
The Pros And Cons Of Price WarsCheaper prices for the customer may seem great, but aggressive price cutting has a downside.
How Global Events Affect The Forex MarketLearn how politics, war and natural disasters move the forex market, and how you should respond.
What Is A Currency War And How Does It Work?We look at what a currency war is, what factors may lead to it, the impacts of such a strategy, and whether there is a currency war currently.
When To Sell StocksBuying at the right price determines profit, but selling at the right price locks it in.
Investing During UncertaintyThe inability to forecast future events can turn the markets upside down. Find out how to stay right-side up.
Will Star Wars Be Killed By Its Own Hype? (DIS, HAS)As Dec. 18 draws near, the expectations around Star Wars are ballooning. Will the movie franchise be able to live up to expectations?
Original Star Wars Trilogy Returning to Theatres in AugustThe oldest three Star Wars movies return to the big screen in August in a special program called "Return of the Trilogy".
Economic Conditions That Helped Cause World War IIDire economic conditions following the First World War intensified antagonisms between nations that would eventually lead to the outbreak of World War II.
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War EconomyThe organization of a country's production capacity and distribution ...
War Exclusion ClauseA clause in an insurance policy that specifically excludes coverage ...
Trade WarA negative side effect of protectionism that occurs when Country ...


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Related Issues
Is Obama About to Take Over the Internet? No.
Some internet policy groups have also expressed concerns. "Frankly, we don't know" what sort of information the government might eventually request from companies, says Mark Jaycox, a policy analyst at the Electronic Frontier Foundation (EFF). "Information sharing is a slippery slope."
At issue is an executive order on cyberterrorism that the White House is widely expected to issue at some point in the coming weeks.
By Dana Liebelson
Friday, November 16, 2012
Mother Jones
Related Issues:


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Lenovo Must Invest to Keep IBM Brands Lure
Opinion: In taking over IBM's struggling PC business, China's biggest PC maker should realize that holding onto brand loyalty will demand a heavy investement in R&D.This is one of these "and then the other shoe dropped" stories, and it involves the IBM-Lenovo deal that sent Big Blues PC business to the Chinese. It turns out, according to SEC filings reported in The Register, that IBMs PC business wasnt just a low-margin business. Rather, it had lost nearly a billion dollars. What does this mean for people who love their IBM ThinkPads? Will Lenovo be a good foster parent, or did IBM sell to the only company idiot enough to buy? Here are the basics: IBMs PC business unit lost $397 million in 2001, $171 million in 2002, and $258 million in 2003. It was on the same pace through the first half of 2004, during which it lost another $139 million. So, in less than four years, IBM lost nearly a billion dollars selling personal computers.
IBM doesnt normally make these numbers public, lumping them with others so its impossible to tell where the company makes money and where it doesnt. Having these losses come to light, however, explains why IBM sold a business with $10 billion a year in revenue to Lenovo for only $650 million in cash.
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Ryan Adams writes freely on Prisoner
The singer/songwriter's latest takes on heartache with '80s guitar cheese
Marcus Perez 8 a.m., Feb. 20
Fitch, the bond rating agency, has affirmed the BBB-minus rating of San Diego County's certificates of participation issued on behalf developmentally disabled and mentally impaired persons. The outlook is negative, says Fitch. The program is called Arc and serves 1800 to 1900 persons. In Fitch's system, BBB bonds have good credit ratings with a low default risk. But BB bonds are speculative. BBB-minus bonds are between the two. Thanks to Matt Potter for sending this along.


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Doreen Lawrence: 'My pain is raw and that of my children'
22 April 2013 Last updated at 20:33 BST
The mother of murdered teenager Stephen Lawrence has said her "pain is raw", at a memorial service to mark the 20th anniversary of her son's death.
The 18-year-old aspiring architect was murdered in a racist attack as he waited for a bus in Eltham, south east London, on 22 April 1993.
The memorial service took place at St Martin-in-the-Fields, near Trafalgar Square in central London.
Doreen Lawrence said: "My pain is raw, and that of my children."


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Alternative websites for 188bet.net
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188BET is an online sportsbook provider. 188BET is owned by Cube Limited, which is licensed and regulated by the Isle of Man.
Alternative for en.wikipedia.org
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Cloud Computing Reducing Costs, Improving Productivity
Nearly two-thirds of respondents report faster access to technology with the cloud.Organizations with more than 500 employees are seeing tangible benefits from cloud computing, with 85 percent saying the cloud has lived up to industry hype and 23 percent declaring that cloud has exceeded their expectations, according to a global study of 1,000 senior IT decision-makers by Tata Communications. Tata reported that 83 percent of enterprises are seeing benefits they did not expect. The most popular of these are increased productivity (69 percent), better access to data (65 percent), and reductions in costs (63 percent). The findings also indicate that by 2024, off-premises storage will have overtaken on-premises alternatives. Enterprises are forecast to have 58 percent of their compute and data storage in the cloud in 10 years, compared with 28 percent currently. "Some of the major challenges a business faces are getting their network to support a cloud platform. Whether that is a private cloud or public, either requires the network to be the "glue" that holds the cloud together," John Hayduk, chief technology officer of Tata Communications, told eWEEK. "So getting the network to have the necessary performance and uptime is critical to making the cloud platform work."
Hayduk noted another challenge is the location of data. Given that businesses can pick cloud platforms or application service providers from anywhere, knowing where a company's data is stored, protected, and who has access to it requires special planning and attention.
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Publicado el 14/02/2017
Oportunidad de empleo | Boston, MA, US
Publicado el 14/02/2017
Oportunidad de empleo | Boston, MA, US
Donor Database Administrator (Part-Time)
Publicado el 14/02/2017
Oportunidad de empleo | Boston, MA, US
Earthwatch Institute
Puestos vacantes
Sobre nosotros
Earthwatch is an international environmental charity.
Founded in 1971, our mission is to engage people worldwide in scientific field research and education to promote the understanding and action necessary for a sustainable environment.
We enable people from all walks of life to join leading scientists working on crucial environmental research projects locally and globally. We're one of the world's largest private funders of scientific research.
Since we were founded, around 100,000 people from the general public have joined Earthwatch in the field, contributing roughly 10,000,000 hours of data collection—far more than our scientists could have collected alone. Our expeditions offer experiences that are very different from those of for-profit tour operators, because our volunteers get meaningfully involved with real scientific fieldwork.
Earthwatch participants assist in activities designed to advance science while experiencing parts of the world tourists never see, and enjoying the adventure of a lifetime in the process.
We bring members of the public together with world-class scientists to work for the good of the planet. These paying participants, aged 15 up to retirees, assist noted scientists in the field for 1-3 weeks. No special skills are required. Project disciplines range from a-z; from archaeology, animal behavior, ecology, marine biology, to forestry, ornithology, paleontology, world health, and zoology. For more information, including full descriptions of our current expeditions, see www.earthwatch.org.
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Fecha de creación: 1971
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Many Monell scientists conduct studies with animals and need to characterize their chemosensory phenotypes. They will benefit from the Phenotyping Core in the following ways. 1) This Core will provide a centralized resource of equipment and supplies that will receive dedicated support and regular maintenance. The Core will also centralize labor-intensive tasks, such as making equipment for preference tests. Studies will be designed and/or conducted by Core personnel with specialized expertise in phenotyping techniques. This will be more efficient than replicating these techniques and personnel in individual laboratories. Regular use and service will ensure that equipment is always operational and available for experimentation. 2) The Core will provide access to equipment and facilities (e.g., LabMaster, surgical facility) that are not practical to maintain in individual laboratories. The Core will offer a range of services and experimental designs that are not available in individual laboratories. 3) Scientists with no experience in animal phenotyping will receive training and will have access to equipment and expertise of the Core. This will facilitate their research and help them to collect preliminary data for grant applications. 4) This Research Core will be an integral component of the Core Center. Interactions between the Phenotyping Core and other Research Cores will facilitate collaborative and interdisciplinary studies that are often not feasible for individual laboratories. For example, the Phenotyping and Histology Cores will be used to characterize genetically engineered mice generated from constructs produced using the Molecular Biology Core. In forward genetics studies, the same animals will be examined using the Phenotyping and Genotyping Cores, and the data obtained will be used for chromosomal mapping studies. We estimate that 9 of the 13 R01 grants in our Research Base will use services provided by this Core at moderate to extensive levels. We also expect that 11 current faculty research groups at Monell will use the services provided by this Core. As a result, the Phenotyping Core will improve the efficiency and quality of animal model studies at the Center, accelerate existing NIDCD-funded projects, and advance translation of the results into benefits for public health.
|Yamaguchi, Tatsuya; Yamashita, Junpei; Ohmoto, Makoto et al. (2014) Skn-1a/Pou2f3 is required for the generation of Trpm5-expressing microvillous cells in the mouse main olfactory epithelium. BMC Neurosci 15:13
|Tordoff, Michael G; Ellis, Hillary T; Aleman, Tiffany R et al. (2014) Salty taste deficits in CALHM1 knockout mice. Chem Senses 39:515-28
|Tordoff, Michael G; Downing, Arnelle; Voznesenskaya, Anna (2014) Macronutrient selection by seven inbred mouse strains and three taste-related knockout strains. Physiol Behav 135:49-54
|Kokrashvili, Zaza; Yee, Karen K; Ilegems, Erwin et al. (2014) Endocrine taste cells. Br J Nutr 111 Suppl 1:S23-9
|Feng, Pu; Huang, Liquan; Wang, Hong (2014) Taste bud homeostasis in health, disease, and aging. Chem Senses 39:3-16
|Parker, M Rockwell; Feng, Dianna; Chamuris, Brianna et al. (2014) Expression and nuclear translocation of glucocorticoid receptors in type 2 taste receptor cells. Neurosci Lett 571:72-7
|Mennella, Julie A; Reed, Danielle R; Roberts, Kristi M et al. (2014) Age-related differences in bitter taste and efficacy of bitter blockers. PLoS One 9:e103107
|van Valkenburgh, Blaire; Pang, Benison; Bird, Deborah et al. (2014) Respiratory and olfactory turbinals in feliform and caniform carnivorans: the influence of snout length. Anat Rec (Hoboken) 297:2065-79
|Mennella, Julie A; Finkbeiner, Susana; Lipchock, Sarah V et al. (2014) Preferences for salty and sweet tastes are elevated and related to each other during childhood. PLoS One 9:e92201
|Adappa, Nithin D; Zhang, Zi; Palmer, James N et al. (2014) The bitter taste receptor T2R38 is an independent risk factor for chronic rhinosinusitis requiring sinus surgery. Int Forum Allergy Rhinol 4:3-7
Showing the most recent 10 out of 33 publications


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Best Western Hotel Berlin-Kurfürstendamm
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Set in an elegant listed building just off Berlin's Kurf?rstendamm shopping mile, this 3-star hotel is a 15-minute walk from the Kaiser Wilhelm Memorial Church as well as excellent connection for the entire city. Free WiFi is available in all areas of the hotel. The Hotel offers en-suite rooms featuring high stucco ceilings and parquet floors with free of charge WiFi available in all areas of the hotel. The Hotel Astrid offer fresh breakfast and the hotel's reception is open 24 hours a days.
Bleibtreustr. 25, 10707 Berlin Charlottenburg, Berlin 10707, Germany


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Pound for pound, the Wharfedale Titan 12 passive PA speaker is one of the most competent loudspeakers, fusing affordability and of course audio fidelity into an exceptionally lightweight polypropylene cabinet. It is 250 Watts RMS, with 128dB Max SPL making a suitable contender for small to medium sized venues.
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If we try to call 'js::SetRuntimeProfilingStack' before we have a JS runtime and before the JS engine is started and we crash. We start profiling on start up in mobile since we use an environment variable to start.
Simple fix is to delay profiling until we get a runtime.
Created attachment 640764 [details] [diff] [review]
Delay JS profiling until we have a runtime
Also use JS profiling by default on mobile.


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Floor Liner, Rear, Gray, 07-14 GM Acadia/Traverse/Enclave
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text: Buffalo Bills 2013 Offseason riley0605 , NFL News Frequently! on March 10 0 After going 6-10, the Bills look to succeed next year. This is how. (sort of) Positions that need improvement: Quarterback- To much trouble from Fitzpatrick Wide Receiver- Need a compliment or possibly a replacement for Stevie Johnson Linebacker- Nick Barnett was released and Kelvin Sheppard was disappointing. Defensive End- Both Mario Williams and Mark Anderson had bad first seasons as Bills. Guard- Andy Levitre is their best offensive lineman so they can't afford to lose him. Punter- Brian Moorman was never anywhere near as bad as Shaun Powell. Who to draft: Quarterback: Tyler Bray- Tennessee- I like Tyler Bray a lot. I think he has a very good arm and the Bills could probably land him in the second or third round. Collin Klein- KSU- Collin Klein is a guy that will probably go before Tyler Bray but after E.J. Manuel. He seems consistent enough so the Bills should look into drafting him. Wide Receiver: Cordarrelle Patterson- Tennessee- He is arguably the best receiver in this draft. However, the Bills have a high enough pick to get him. Keenan Allen- Cal- A speedy receiver who also can play special teams. Linebacker: Manti Te'o- Notre Dame- Possibly the best inside linebacker in this draft, he is a great option. Alec Ogletree- Georgia- Nick Barnett is gone so the Bills probably could get this impressive middle linebacker. Jarvis Jones- Georgia- The best outside linebacker in the draft. Defensive End: Ezekial Ansah- BYU- A really great football player who loves the game. Bjoern Werner- FSU- A great player when he really tries. Dion Jordan- Oregon Barkevious Mingo- LSU Guard: Jonathan Cooper- UNC Chance Warmack- Alabama Punter: Ryan Allen- Louisiana Tech Brad Wing- LSU Bills offseason done. Show Comments Comments (2) Likes & Reblogs


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Mark Solomon (Washington )
Had a bad accident which left me with a fused slower spine and unable to get my Vortices on and off without imitating a pretzel for half an hour. Not as tough as the Vortices I had to sell, but better than my ST Airs, if not as all-day comfortable. Main difference for me is that I can get them on and off as I'm hoping to return to the track next year. I've worn Sidis for the past 8 years and it will take a lot to get me to change. Will probably get another pair of these as the main downside is they don't have replaceable lowers.
ralph (forney )
these boots are great! ankle can move up & down witch is why I bought them, unlike other boots that are super stiff,ie suck!
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Ron (Spring )
Similar comments to what Scott wrote: I got these in the same size as my running shoes (about 1/2 size over dress shoes) and the boots never felt really comfortable. They're just too tight to the point of hurting. Thinking it's a matter of breaking-in, I started riding in the Sidi's, but they never become comfortable enough. I just ended up ordering a 2nd pair a full size larger and hope that these will fit as expected. Will make someone else happy with the barely worn smaller pair.
Marek Gruszecki (Seattle )
I have had these boots for last 5 years and love them. They have been equally comfortable riding through Alaska rain as well as the desert in Nevada. It is a great value for the money.
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Nice design & great colors. Look superb on my bikes! Very easy to peel off , w/ a blade of course.


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How the world was won: Match analysis
Never mind the football – here's the planet's first proper holiday tournament. While England square up to the US in Rustenburg tonight, The Independent Traveller can exclusively reveal the results of the World Cup of Holiday Destinations (WCHD).
Independent Graphics
The Group Stage
The Independent Traveller's WCHD group stages follow those prescribed by Fifa's draw, made six months ago in Cape Town – and the early battles reflect the footballing prowess of Britain's favoured tourist destinations. In Group A, France relies on a strong strike-force of Brittany, Normandy and Provence – plus the midfield reach of winter resorts such as Chamonix – to ease past South Africa (star performer Kruger National Park). The hosts themselves just pip Mexico (gutted to be out despite an impressive performance out on the right wing from the Yucatá*Peninsula) and therefore become the only representative from Africa to survive the group stage.
Group B sees comfortable victories for Greece (stand up Athens, Rhodes and Crete) and a surprise second place for South Korea (87,000 visitors per year trouncing the 56,000 of strongly fancied Argentina, where the wonders of the River Plate failed to perform as convincingly as the bright lights of Seoul).
In Group C, England uses the energy of the Lake District to good effect, then employs left-back Cornwall to thrash up-and-coming Slovenia. But there's a threat from the US, with Mickey Mouse from Orlando firing in a series of extravagant goals. Algeria, meanwhile, remains off the UK tourist map.
Elsewhere, Germany flatters to deceive at the top of Group D, with cruises along the Rhine attracting an older market, while Australia has a team filled with individual promise (Sydney, the Great Barrier Reef, Uluru) but which suffers from terrible jetlag.
The other four groups run out roughly as expected, with city-breaks to Amsterdam serving the Netherlands well in Group E, and Portugal and Brazil adding Lusitanian appeal to Group G at the expense of the Ivory Coast and the handful of British tourists reportedly paying their respects to Kim Jong-il in North Korea.
No-hopers Chile (no direct flights) and Honduras (ditto) are embarrassed by Spain in Group H (thanks to star striker the Canary Islands, with around one million visitors to Tenerife alone in 2009). Switzerland slaloms into second place, with Alpine ski resorts providing defensive height. But what's Slovakia doing through to the next round, with a place alongside Italy from Group F? The Tatra Mountains outclass New Zealand's epic Milford Sound by just 3,000, barely more than the total of British visitors to the group laggards, Paraguay.
The Second Round
Things get a little clearer: plucky little Portugal brings on super-sub the Algarve, which easily bypasses Switzerland's central defensive duo of Verbier and Zermatt. Greece then thumps South Africa (the package holiday transfer market paying dividends there). Meanwhile Italy, with a squad including Venice, Rome, Lake Como, Tuscany, Sicily, olives, wine, sunshine and millennia of culture, utterly destroys Denmark (even with Legoland in goal). England slips past Australia with ease; a decent Bordeaux from France beats sipping soju in South Korea; and staying closer to home, the mighty mountains and Zlaty Bazant beer of Slovakia are beaten by the low-rise delights and Heineken of the Netherlands.
The glamour match is Spain versus Brazil, where decent ferry routes and the sports bars of the Costas prevail over the romance of Rio. And then, big news: the Sunshine State brings flair and the Big Apple adds grit (plus Bloomingdale's) as the US puts out Germany, with only Hamburg and Frankfurt showing any appetite for the fight.
The Quarter Finals
The first battle of the touristic titans sees England wiping the floor with the French – Cannes and St-Tropez proving no match for Bognor and Bridlington, with a winning margin of 92 million. And still they come: Las Vegas is a key player as the US ups the ante by kicking Greece back into antiquity; and Spain trumps Italy by a stunning 10.4 million annual visits . The Iberian peninsula scores a double: port and Madeira help Portugal ease past Holland. What were the Dutch smoking?
The Semi Finals
They think it's 1966 all over again: it is now, as England beats Portugal, with the Isle of Wight and the Scillies towering over the Azores. And even Mickey Mouse can't stand up to a combination of having it large in Ibiza and taking it slow in Seville, so Spain wins through to the final.
The Final
And the winner is... England. It was never really in doubt, with the domestic tourism market enjoying a home advantage since long before 1966. Nevertheless, Spain offered up decent opposition in the final as our favourite package holiday destination.
Turkey, you should have been there: 2.4 million visits by British tourists could have seen you through to the quarters finals. And an honourable mention for Scotland, again absent from the party: 12.5 million UK tourists in 2009 could, with the right draw, have seen the Scots take on the Auld Enemy in the glittering culmination of the World Cup of Holiday Destinations. Now that would be worth watching – with no passport required.
Ben Ross
Home and Away: Hot tickets to the Top 16
Match-winner: Sydney has its epic harbour; Bondi beach is within easy reach.
Dream Ticket: £639 return on China Airlines via Taipei through trailfinders.co.uk .
Match-winner: Rio for mountains, beaches and Carioca cool in one vibrant city.
Dream Ticket: BA has flights from Heathrow this month from £634 return ( ba.com ).
Match-winner: Copenhagen's restaurants boast more Michelin stars than Rome, one of which is Noma, voted the world's best restaurant.
Dream Ticket: from £65.60 return from Gatwick this month with Norwegian ( norwegian.no ).
Match-winner: London, for the sheer breadth of history and culture – and the forthcoming Olympic Games.
Dream Ticket: £80 per person per night with breakfast, at the four-star Shaftesbury Premier London Notting Hill through Directline Holidays ( directline-citybreaks.co.uk ).
Match-winner: with vineyards, beaches, mountains, lavender fields and that artist-favoured light, Provence is hard to beat.
Dream Ticket: seven nights for the price of six at the four-star Hotel Belle Plage in Cannes in July and August: £789 per person including Eurostar ( f-t-s.co.uk ).
Match-winner: Berlin, one of the most visited destinations in the EU: the Brandenburg Gate is its centrepiece.
Dream Ticket: £82 return from Stansted this month with Air Berlin ( airberlin.com ).
Match-winner: more than 6,000 Greek islands mean there are thousands of holiday opportunities.
Dream Ticket: £410 for flights and a week in a three-bedroom villa in Corfu with Ionian and Aegean Island Holidays this month ( ionianislandholidays.com ).
Match-winner: world-class wine, Renaissance cities, beaches and a leaning tower – it can only be Tuscany.
Dream Ticket: seven nights from £239 in September with Eurotunnel crossings through Cresta ( crestaholidays.co.uk ).
Match-winner: Amsterdam, for art, culture, and canals.
Dream Ticket: the cheapest returns this month start at £59 from Gatwick with easyJet ( easyjet.com ).
Match-winner: the Algarve isn't all golf; new design-driven hotels are giving the region a stylish makeover.
Dream Ticket: seven nights in Vilamoura with flights from Birmingham in late June from £460 B&B through Monster Travel ( monstertravel.co.uk ).
Match-winner: the Tatra Mountains, with lakes, Alpine peaks and national parks.
Dream Ticket: The Grand Hotel Kempinski High Tatras is offering midweek stays from €75 per person including breakfast ( kempinski.com ).
Match-winner: Cape Town boasts wild Atlantic scenery and Table Mountain, plus some great dining options.
Dream Ticket: £1,399 for nine nights in a boutique B&B plus flights between mid-July and August through Destinology ( destinology.co.uk ).
Match-winner: Seoul Special City deserves its title for being the world's biggest city, as well as this year's World Design Capital.
Dream Ticket: return flights from £575 later this month with Emirates via Dubai through expedia.co.uk .
Match-winner: the southern region of Andalucia packs in sun-soaked beaches, Moorish history, oranges and olives.
Dream Ticket: James Villa Holidays has seven nights at Villa Laura, Nerja for £272 with flights from Luton at the end of June ( jamesvillas.co.uk ).
Match-winner: whether slaloming in winter or hiking in summer, the Swiss Alps have year-round appeal.
Dream Ticket: £499 for seven nights' half board in Saas Fee with flights departing later this week through Inghams ( inghams.co.uk ).
Match-winner: yes, it has New York, the Pacific West Coast and Florida, but none can match the majesty of the Grand Canyon.
Dream Ticket: North America Travel Service has a six-night break in Las Vegas and the Grand Canyon from £1,335 per person with flights ( northamericatravelservice.co.uk ).
Sophie Lam
SOURCES: All figures are from The Office for National Statistics except: Algeria from the Algerian Consulate; Netherlands from the Dutch Tourist Office; Brazil, Ghana and Uruguay from the Foreign Office; Cameroon from the Cameroon Embassy; Chile from the Chilean Embassy; South Korea from the Korean Tourist Office; Paraguay, Argentina and Honduras from the Latin American Travel Association; Nigeria and Ivory Coast are industry estimates
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There's a dirty secret behind many of those hot new app startups you hear about every week. They have seed funding and a flashy landing page. They have articles in TechCrunch and promises to disrupt the universe. They have everything except users, because nobody actually wanted the app.
In a presentation at Google's I/O conference, Tomer Sharon, Google Search User Experience Researcher, broke down the age-old question: "Why is nobody using my app?" You can watch the entire presentation in the video embedded below, but we simplified the 30-minute presentation into the key takeaways for those who prefer a quicker skim.
Here are the six reasons why nobody is using your app:
You Didn't Understand The Problem You Were Solving
Does your app solve a real problem that people have? To validate this assumption, many startups create a landing page to gauge interest in lieu of real product testing. You've seen them. It's a website that makes a bold promise like, "We're about to change the way you buy tacos forever! Sign up here!" The problem with this approach, Sharon explains, is that the only thing you're really learning is who is interested enough to give their email address. Whether or not your app fulfills a real need, worthy of someone's time and attention, is a whole other question.
You Asked Your Friends What They Thought
Your mom will always love everything you do. Your friends will always pretend to love everything you do. So asking your friends and family what they think of an app can be borderline useless. "They're biased," Sharon explains. "Of course they like your idea. Sure, they'll use it. Of course they'll pay for it—a lot!" Instead, break out beyond your immediate cohort. Talk to whomever your target market is for your app.
You Listened To Users Instead Of Watching Them
So creating a landing page and asking your friends isn't enough? Well then, polling a lot of users—asking if they'd use your app—seems like a surefire way to design the perfect app, doesn't it? "The first rule of research is don't listen to users," Sharon says. "Instead, observe their behavior."
Sharon points to a recent study of U.K.'s motorway toilets, in which 99% of people claimed to have washed their hands after leaving the bathroom. But when equipment was installed to track real habits, it turned out that only 32% of men and 64% of women actually did wash their hands. "Some people would say, they're just liars. They're not," Sharon says. "We are having trouble predicting our behavior. There are many reasons for that."
You Didn't Test Your Riskiest Assumption
Every product makes assumptions, but there's one assumption that's most important. It's what Sharon calls the "riskiest assumption," the assumption most core to your product. "If the riskiest assumption is not true, then the whole idea falls apart," Sharon says.
Let's imagine how this idea could have played out historically. When YouTube launched, they assumed we'll know to click a play button, that people would recognize how to scrub through a clip, and that bloggers would embed videos into articles. But the riskiest assumption might have been even simpler back then: People will upload videos if it's quick and easy. Hindsight is 20/20, but testing that assumption would be critical in ensuring the successful launch of YouTube.
You Had A "Bob The Builder" Mentality
Right now, it's very popular to quickly launch an app with barebones functionality, see if it sticks, "pivot" (or change the fundamental functions of a product), then essentially relaunch it. Rather than designing a product for real human use, it takes on an entrepreneurial workflow, a strategy to maximize a startup's bets before they run out of money. Sharon calls this a "Bob the Builder mentality."
And while this approach can work—Instagram, which was originally a check-in service called Burbn, might be the poster child of pivoting—Sharon insists that it's not the way to build a successful app. Just because something can be coded again and again doesn't mean it shouldn't have been designed based upon real human needs and user insights in the first place.
The Alternative
So what's the solution? Sharon says it's as simple as validating, or invalidating, three core pieces of the plan: The problem (Is the app solving a problem people care about?), the market (Are there enough people who have this problem?), and the product (Is our product solving this problem for this market?). Of course, this is standard business plan stuff, isn't it? In the culture of startups, it's easy to forget that apps are businesses.
But we think Sharon's best piece of advice is about how you really talk to your market so they'll give you feedback worth listening to. When you poll potential users, doing all your research about real human needs, ditch those things you can easily average to lose the nuance. Avoid yes or no questions. Skip numerical response. Instead, he wants you to ask about repeated behaviors, and preferably as short-answer feedback.
A good question:
"What was the reason you recently updated your website?"
A bad question:
"How many emails did you receive in the last hour?"
Because fundamentally, a well-designed app is like any other well-designed product. It's shaped around human need. And the more viscerally you can understand that need, the more relevant your product will be.


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Web Client Project
This project received 9 bids from talented freelancers with an average bid price of $1878 USD.Get free quotes for a project like this
Project Budget$1500 - $3000 USD
Total Bids9
Project Description
We're a San Francisco, CA based tech start-up looking for an experienced engineer.
If you're a web developer seeking the challenge of producing beautiful UI with fairly complex interactions, this project could be for you!
The Proof of Concept (POC) is a web-client, GWT project with a time-span of 5 days.
Some skills required are:
Google Web toolkit
The developer will be compensated $1,800 upon completion of the POC and if done well, could potentially lead to a larger project for about $15K.
The UI we're looking to develop is a single screen with 3 representations of a data set. The 3 representations are linked, meaning: changing the data in one representation also changes the data in another representation in real-time.
If you're interested, fill out this form here:
[url removed, login to view]
and we'll be in contact with you!
Skills Required
Looking to make some money?
- Set your budget and the timeframe
- Outline your proposal
- Get paid for your work
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Consists of individual portraits of member of the Haas and Lilienthal families, photographs of weddings, and other family gatherings (in Lake Tahoe and on Mount Tamapais), and photographs of the interiors and exteriors of homes owned by members of the Haas and Lilienthal families.
Haas and Lilienthal family photographs, ca. 1890-1 ...
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Gunday is like the dusty minefields it is set in. Its loud explosions deliver loads of coal, but no trace of any diamonds. It is certainly not the ideal date film on this Valentine's Day weekend.
Priyanka Chopra, Ranveer Singh: "All three films we have done together have been different in dynamics," said Priyanka Chopra
Ranveer has written the lyrics to a rap song which will be out soon. The Gunday actor will also sing and perform the rap in a digital video
"I am very proud of Arjun. He is evolving as an actor. The most important thing is to grow with each performance and Arjun is doing that with his every single film," Ranveer said at a screening of Ki And Ka
Actor Arjun Kapoor said that he is scared of losing out on his loved ones, both on screen and in real life, and added that it is one of the reasons he is hesitant to watch Sonam Kapoor's Neerja. The Gunday star made the revelation in a video shared on Twitter
Ranveer Singh and Arjun Kapoor are all set to star in a YRF web series which will be directed by newcomer Ashish Patil.
Ranveer Singh said that Priyanka Chopra and Deepika Padukone are lucky for him. "Whenever I do a film with Priyanka or Deepika, the film becomes a success, such as Gunday, Dil Dhadakne Do, Ram Leela and Bajirao Mastani. These two special ladies are very lucky for me," said Ranveer.
Actor Ranveer Singh has been signed for upcoming YRF film Befikre, which will be directed by Aditya Chopra, and Arjun Kapoor says that the film is 'nice and apt' for his Gunday co-star. "Aditya Chopra will use aspects of Ranveer's personality to do justice to the film and the title."
Arjun Kapoor said his "chemistry" with Ranveer Singh is a result of "genuine friendship and it's rare to be seen in today's time". On turning 30 last month, the Gunday star joked, "Abhi toh life ki interval reel shuru hui hai."
One of Bollywood's most talented and versatile actresses, Priyanka Chopra has come a long way in her career. She has not just proved her mettle as an actor but has also showed her vocal talent with her third single I Can't Make You Love Me.
We finally see Jacqueline Fernandez sharing the limelight with Salman Khan in this brand new poster of their upcoming movie Kick.
We Bang Banged into this picture of Bollywood actor Hrithik Roshan who is shooting for his upcoming movie in Prague.
We finally managed to catch Bollywood actors and rumoured lovebirds Deepika Padukone and Ranveer Singh on camera off-screen as they made their way out of Mumbai's Olive Bar on Sunday, April 13.


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If you find yourself in Bigfork Montana; you have to indulge yourself and take the all day Swan River float fly fishing trip with Guides Matt and Bart. The scenic river views are...
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If you find yourself in Bigfork Montana; you have to indulge yourself and take the all day Swan River float fly fishing trip with Guides Matt and Bart. The scenic river views are amazing. We saw a Bald Eagle, Hawks, deer, and the Guides pointed out many of the colorful birds that call the river home. We had a wonderful...
Our family went for a 1/2 day fly fishing trip with Matt and Sam. Even though we are novice fly fishers, with the expert guiding by our captains, each boat caught about 12 nice size trout of various types. The guides are extremely knowledgable about the river and taught us a lot about the area. The boats and rods were...
I was lucky enough to go on a guided trip with Matt and the Guys from Crane Mountain. The boats were set up perfectly for fly fishing in this area of the Upper Swan River. This was the first time I had been on a guided trip and was impressed with the skill and patience Matt had getting me up...
We booked a full day float trip with Matt and he was great! The Swan River was beautiful and the views of the mountains were incredible. Matt was incredibly kind, and provided us a quick lesson, as this was our first time fly fishing. He knew the river very well and took us to areas where he knew the fishing...
Own or manage this property? Claim your listing for free to respond to reviews, update your profile and much more.


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Waning appetite for bangers and mash in the UK has produced a 4.5 per cent fall in annual profits at the sausage-skin maker Devro.
Soaring pork prices have led to a decline in UK sales of sausages, chorizo and pepperoni in the UK, with a 5 per cent drop in demand in the past two years.
Sales in Europe, Australia and Russia have not been much better and, although Devro met City forecasts with a pre-tax profit of £37.5m for 2013, its weak outlook for 2014 prompted a 9 per cent fall in the shares to 277p.
The chief executive, Peter Page, said the outlook "for important markets, such as the UK, Russia, the US and Australasia, is less clear".
He added that the group will consider cuts at factories where the cost of production is highest, to reduce expenses this year.
Sales in the hot-dog nation of the US were up just 2 per cent. But there was better demand in emerging markets such as China, South-east Asia and Latin America, where total sales volumes of sausage casings jumped by 10 per cent.
Devro said it will invest £50m in a new manufacturing plant in Nantong, near Shanghai, to meet Chinese demand.Reuse content


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Extra powerful motor provides highest torque in its class. Sturdy aluminium gear-housing for increased durability. Ergonomically designed soft grip for superior control. Retractable belt clip allows operation in tight a... show more
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Brushed Artistry/ Makeup by Maddy offers mobile services catered to you at your venue; specializing in airbrush makeup.
Did salon services meet your wedding needs? Why or why not?
The salon services met every expectation that I had.
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The atmosphere was absolutely amazing relaxing and calming, something you need the day of your wedding. The overall experience was perfect, and couldn't ask for anything else.
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Copyright © 2001-2017 OneWed Inc. All Rights Reserved.


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News Release
Commerce Department Privacy Report Leaves Consumers In The Cold, Recommendations Favor Current Industry Practices, Consumer Watchdog Says
WASHINGTON, DC — The Commerce Department's "Green Paper" about online privacy is an industry friendly document that would perpetuate current failed practices that give companies, not consumers, control of consumer data, Consumer Watchdog said today.
The report calls for "voluntary, enforceable codes." It proposes relying on a failed self-regulatory model when it's clear that real regulations with meaningful enforcement are necessary, Consumer Watchdog said.
"The Commerce report starts off on the wrong foot with the title, 'Commercial Data Privacy...' We are talking about consumers' data and their right to privacy, not about a business commodity," said John M. Simpson, Consumer Advocate with the nonprofit, nonpartisan public interest group. "This is an early Christmas gift to the data collection industry."
"There is a fundamental conflict of interest in putting the administration's Privacy Policy Office in the Commerce Department. The department's job is to promote business. Protecting consumers is simply not on its agenda," said Simpson.
Consumer Watchdog said that even though the Commerce Department's proposals are inadequate to protect consumers, the report will play an important role in prompting necessary debate about privacy policies.
On Dec. 1, the Federal Trade Commission issued its own online privacy report, which noted that industry self-regulation has failed to protect consumer privacy.
Consumer Watchdog has been working to protect consumers' online privacy rights and educate them about the issues through its Inside Google Project. The goal has been to convince Google of the social and economic importance of giving consumers control over their online lives. By persuading Google, the Internet's leading company, to adopt adequate guarantees, its policies could become the gold standard for privacy for the industry, potentially improving the performance of the entire online sector.
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Consumer Watchdog, is a nonprofit, nonpartisan consumer advocacy organization with offices in Washington, DC and Santa Monica, CA. Consumer Watchdog's website is www.ConsumerWatchdog.org. Visit our new Google Privacy and Accountability Project website: http://insidegoogle.com
Action Alert
2/2/2017News StoryWashington --The Federal Trade Commission will focus on fraud and be judicious in making paperwork requests when it opens an... More >
4/19/2016News ReleaseConsumer Watchdog Urges Federal Trade Commission To File Antitrust Charges Against Google Over Android Operating System AbusesSANTA MONICA, CA – Consumer Watchdog today urged the Federal Trade Commission to file antitrust charges against Alphabet... More >
5/10/2016News ReleaseWASHINGTON, D.C. – Consumer Watchdog today joined a coalition of a dozen consumer groups in supporting the Federal... More >
5/23/2016News ReleaseFCC's Set-top Box Plan Would Increase Competition And Cut Costs, But Should Not Be Enacted Unless Pandora's Box Of Privacy Issues Are Solved, Consumer Watchdog SaysSANTA MONICA, CA – The Federal Communications Commission's plan to open the set-top box market to competition offers... More >
6/22/2016News ReleaseConsumer Watchdog Opposes California Sen. Hueso's Bill That Would Limit Criticism Of Shady Business PracticesSANTA MONICA, CA – Consumer Watchdog today opposed SB 726, a California Senate Bill that would curtail the ability for... More >


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- Anonimo
- Germania, Maschio, 25-30
- Nomade principiante
- 3 Recensioni
Nice location & nice Hostel (clean rooms & bathrooms!) I would recommend to stay there!
- Anonimo
- Francia, Coppia, 31-40
- Viaggiatore appassionato
- 11 Recensioni
Nice hotel near the ocean in a small fishermen neighborhood not far from Pisco.
- Anonimo
- Inghilterra, Femmina, 18-24
- Nomade principiante
- 4 Recensioni
Very nice rooms in the hostel and very clean. Owner Manual was the only one who spoke English and was helpful.Breakfast was nice and showers were always hot. Area wasn't to nice but there were good fruit markets which sold things fresh and very cheap.
Applicazioni di Hostelworld per cellulare
Prenota dove vuoi e quando vuoi con le nuove app per dispositivi mobili di Hostelworld.


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- //Home
- //DVDs
- //Reviews
- //Tales of the City
Tales of the City (20th Anniversary Edition)
(Channel Four)
US DVD: 27 Aug 2013
Tales of the City was an absolute revelation when it ran on PBS in 1994, and not just because public television was showing a mini-series full of sex and drugs and gay characters who were part of a community and had lives and loves as real and complex as those granted the straight characters. That's all very nice, but Tales of the City spoke directly to me because it was about a naïve and painfully unhip young woman from the Midwest choosing to leave behind her safe, programmed life in Cleveland, where the height of aspiration is living in one of "those new places out at Ridgemont" (with curtains custom-made by her mother), and take a chance on creating her own life among the fleshpots of San Francisco.
Here's two other things that seem revelatory in retrospect, although I didn't notice them back in 1994: 1) although Tales of the City features a large and varied cast of characters, the two most central are both female, and 2) Mary Ann Singleton (Laura Linney), the young woman determined to leave Cleveland behind, is awkward and unsure and makes a lot of mistakes in the process of finding her life (note: her life, not just Mr. Right). On the first point, it's no secret that American television and films these days are dominated by stories about men (check out some of the research posted on seejane.org if you don't believe me). As for the second, I've always been allergic to the wish-fulfillment type of story, in which everyone gets what they want much too easily, while hardly seeming to set a foot wrong in the process.
Of course, two decades can be an eternity when it comes to pop culture, so a revelatory mini-series of 20 years ago could easily seem hackneyed today. That's not exactly the case with Tales of the City, but watching it again after all those years, I was far more aware of its flaws, while still enjoying its good qualities. I also noticed many, many things that I missed the first time, including copious Vertigo references as well as clever little clues planted almost from the start that foreshadow the big reveal near the end.
Tales of the City is based on a novel written by Armistead Maupin and published serially (just like Charles Dickens!) in the San Francisco Chronicle in 1978. It focuses on a diverse of characters living in an apartment house at 28 Barbary Lane, a fictional address whose real life counterpart is the woodsy Macondray Lane on Russian Hill. The landlady, Anna Madrigal (Olympia Dukakis, in one of her great roles), grows her own pot and, in her own words, "has no objection to anything." Mary Anne moves in, and soon meets the other residents, including the tie-dyed fag hag Mona Ramsey (Chloe Webb) and her gay best friend Michael "Mouse" Tolliver (Marcus D'Amico), the very handsome and quite aware of it Brian Hawkins (Paul Gross), and the rather disturbed Norman Neal Williams (Stanley DeSantis).
Mary Anne quickly finds a job working at an ad agency run by Edgar Halcyon (Donald Moffat), a plot move that brings in a whole new flock of characters, including Halcyon's wife Frannie (Nina Foch), daughter DeDe Halycon Day (Barbara Garrick), and slimy son-in-law Beauchamp Day (Thomas Gibson). And therein lies my main difficulty with Tales of the City: while I love the scenes featuring the residents of 28 Barbary Lane, there's far much too much screen time wasted on rich people who are so whiny and boring that I don't feel sorry for them, I just want them to go away. Not Edgar, though: Maupin made him a complex, sympathetic character, and provided him with a secret (revealed to the audience early in the first episode, but not to the other characters until much later) that pushes him to seek something more than his rote, rich white guy existence.
Tales of the City is constructed as a series of blackout scenes, cutting abruptly among the different story lines, which frequently cross and thus bring characters from the different stories in contact with each other. This approach is faithful to the original material, and also feels true to my experience of life in the big city, which can feel like a very small town at times. It's also worth noting that this type of construction felt a lot fresher before it was done to death by Alejandro González Iñárritu and his imitators (note: Tales of the City aired in the U.K. seven years before Amores perros hit the big screen).
The production design (Victoria Paul), costumes (Molly Maginnis), art direction (Lee Mayman) and set decoration (Joyce Anne Gilstrap) of Tales of the City are all excellent—the screen is simply overflowing with the highlights and lowlights of Seventies culture, and that's another great pleasure of watching this mini-series. Unfortunately, the visual quality of the DVDs are poor: the colors are frequently muddy, and the picture is soft and grainy, to the point where you frequently have to watch through the images rather than immersing yourself in the experience.
The two-DVD set of Tales of the City comes with some nice extras, including an eight-page insert with notes from Armistead Maupin and producer Alan Poul, commentary tracks for three of the episodes, and thirteen behind-the-scenes clips showing rehearsals, set construction, and the filming process.
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urgent matlab and ANSYS task
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Project Budget$10 - $30 USD
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Plz focus on Matlab work then compare it with true result which is in the end of the question
The ANSYS just easy but at the end
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Fisrt Math work then apply the equation as matrix on Matlab Then put your work in ANSYS PROG then the write the report
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Dried spearmint
Verified Purchase
Dried spearmint
Dried spearmint, as simple as that.
Alvita Teas - Spearmint Leaf Tea
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Exactly what I've been looking for! Spearmint, great taste, no caffeine. Quick shipping, and arrived in perfect condition too.
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smells nice and tastes good; not too strong and just right. I like the fact that there's no strings and staples attached to the tea bags. Good product :)
spearmint tea
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These are great - extremely hard to find spearmint tea bags - so I will buy again - fairly good price.
Spearmint Leaf Tea Bags
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Very pleased with this order, it came very fast and the Spearment Leaf Tea Bags were much better than I expected. I will be ordering again soon. Thanks.
Good Tea
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Good tea - very delicious and I find quite reasonably priced for the product.
Dried spearmint
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Spearmint Tea
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Great product! Recommend to all! Taste great and you can reuse the bag more then once and it still taste great! Will be buying more!!!
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Looked everywhere for just spearmint tea, and finally found it. It is delicious hot or iced. Great service by seller.
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Chieftain Insurance Company Profile
Established in 1999, Chieftain is a product of The Dominion. Chieftain is the right insurance choice for those who value quality and simplicity. Chieftain offers insurance packages that provide comprehensive coverage through a standardized set of features and a range of straightforward options. Chieftain provides "one-stop shopping" for quality coverage, competitive pricing, numerous discounts, excellent claims service and the convenience of monthly credit card payments.
Chieftain Insurance quotes are available on InsuranceHotline.com for auto and property insurance and offered through a network of independent licensed insurance brokers who subscribe to our service.
Chieftain Insurance Canada is a division of Dominion insurance company. Chieftain offers both automobile insurance coverage and home insurance. Insurance products are supplied through various independent brokers throughout Canada. Online automobile insurance quotes and purchases are available.
Automobile Insurance
Automobile insurance shares risk for any accident or other type of damage. Purchasing an automobile insurance policy means that the car is covered against any damages, liabilities, or injuries that may result from the use of the automobile. An insurance premium is purchased for certain amounts of coverage, and a deductible is selected for the particular policy. Car accidents, theft, and vandalism claims against the automobile policy are accepted. The vehicle involvement in any of these types of claims may be covered under a purchased automobile policy.
Automobile Insurance and the Law
Most jurisdictions require that all vehicles have a certain type of insurance coverage. This protects the automobile investment, the banking loan, or the other driver. An accident claim would involve a determination of who is at fault. Fault may generate either a total fault claim, or fault may be determined to be shared by a certain percentage. Driving on public roads with an automobile may require a certain amount or type of coverage. Usually there is a minimum amount of collision coverage that is required. Collision coverage means that the automobile will be insured against any damage or liability for the other driver or automobile.
Comprehensive insurance coverage says that the automobile and the other driver and automobile are covered against any fault that the vehicle may be involved in. Leasing companies and banking institutions prefer to have a comprehensive policy for the vehicle that is being driven. This means that the automobile will be repaired if there are damages to the car.
Purchasing Automobile Insurance
Purchasing insurance may be completed through a private carrier or through a government agency. The particular group that is providing the insurance may differ depending on the location where the automobile is registered.
Making an Insurance Claim
Making an insurance claim may involve an appraisal of the car damages. If the vehicle has been stolen or vandalized, then this type of insurance claim will take into account the amount of the loss. A deductible amount may be a part of any insurance claim. This means that the policy holder will pay the determined deductible first. The insurance company pays the balance of the claim for the amount of the car repairs or car replacement.
Deductibles may not be required under these circumstances:
1. Damage to the vehicle has been caused by another driver, and the car owner is not at fault.
2. There is a third party liability clause that is included in the automobile policy. This clause says that the insurance company will be responsible for damages.
3. The policy holder has made a claim for accident benefits and injury benefits.
4. The car is declared a total loss. This type of loss may occur as a result of a vehicle theft. A total loss of a vehicle may be due to fire.


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Creative Biolabs develops and commercializes a full range of integrated innovative services that are based on phage display technology. We have ...
Creative Biolabs can offer advanced protein engineering platform for your specific project, including high-scale expression, crystallization and characterization...
Creative Biolabs has established custom membrane protein and membrane protein antibody production platforms for antibody discovery...
Creative Biolabs provides a full range of services based on our matured hybridoma platform. Our featured services involve the custom monoclonal antibody production, from ...
Creative Biolabs is gladly to show a series of unrivalled de novo antibody sequencing services for research, diagnostic and therapeutic industries. To overcome the current drawback of sequencing based on traditional methods, Creative Biolabs has developed the proprietary Database Assisted Shotgun Sequencing (DASS) technology, which based on our next generation antibody sequencing platform. Our services consist of variable region, variable plus leader region and full length heavy- and light-chain antibody sequencing for all species, isotypes and allotypes. Purified monoclonal antibodies in multivalent forms can be sequenced with 100% coverage of the desired regions as well as excellent accuracy. Numerous successful cases from Creative Biolabs have confirmed our qualification to provide antibody sequencing with 100% accuracy and satisfaction guarantee to meet our customers' needs.
Our world-leading DASS system provides reliable supporting proof for:
• Confirmation & validation of produced mAb
• QC analysis
• IND/NDA application
Fig. 1 De Novo Antibody Sequencing Workflow
Service Specifications:
Sequencing of the V and J and C segments by DASS
The V and J and C gene segments of antibodies are available in public databases. However, during the maturation of an antibody, the B cell introduces hypermutations into the sequence to optimize the affinity. Our mapping algorithm is error tolerant and can match the "mutated" peptides to the corresponding germline, reliably.
Due to the high number of peptides, we get sequence information for EVERY peptide bond in the antibody. Typically, 20-70 different MS/MS spectra are generated for each amino acid (AA) position. Hence, even the hardest sequences of proline and arginine rich peptides can be resolved. As the order of all amino acids is clear, there is no need for time consuming techniques like edman sequencing. If we do not reach 100 % coverage, you will not be charged.
De Novo sequencing of the CDR3 region
While the CDR3 of the light chain is mostly encoded by the germline sequences, the CDR3 of the heavy chain is usually not available in databases. It is encoded by the so called D-segments but these are modified by nucleases and terminal transferases. Typically, only 1-4 AA of a D-segment remain in the matured antibody. The rest of the D-segment is "artificial" and has to be sequenced de novo.
Our method generates many overlapping peptides during the fragmentation process, enabling us to sequence very long stretches of unknown amino acids. The high quality of MS/MS spectra in combination with intelligent data mining, allows us to read the CDR3 like a book. The technique is so powerful, that we were able to sequence a 20 kDa protein, which had no homologue in the database.
Isobaric amino acids
In contrast to other MS based methods we can discriminate most isobaric amino acid combinations. E.g.:
• W can be distinguished from GE, AD and SV (by mass difference) .
• R can be distinguished from GV (by mass difference) .
• Q can be distinguished from GA and K (by fragment spectra and mass difference) .
• N can be distinguished from GG (by derivatization and fragment spectra) .
• Leucine and isoleucine cannot be distinguished. However, most of these positions can be determined using the corresponding germline sequence (see Fig. 1). As antigen binding is mostly mediated by salt bridges and hydrogen bonds the impact of Leu/Ile is usually negligible.
Sequencing of fluorochrome mAbs, IgMs and other non-standard antibodies
• Our method is usually not affected by small ligands (FITC, Biotin, Alexa) coupled to antibodies. Larger protein ligands make sequencing slightly more difficult. However, this can be compensated by using a higher protein concentration, because sequencing quality is dependent on sample amount.
• IgMs can usually be sequenced like normal IgGs. Slightly more sample may be required. As the constant region is modified by several glycans, which cannot be cleaved by PNGase F, we can only guarantee complete coverage for the variable part of the antibody.
• Our method works best with mouse and rat antibodies. However, ~50 antibodies from rabbit, hamster and lama have been sequenced successfully.
• Some mAbs are coupled to matrices. This is compatible with our sequencing method but more sample may be required.
• Many older hybridoma produce 2 light chains (one is a Kappa-chain of myelom MOPC 21). These mixtures can usually be sequenced, even when the MOPC 21 kappa chain is in twofold molar excess.
Fig. 2 Sample sequencing results
Validation of your sequence
Before we start sequencing, the masses of the reduced light- and heavy-chain will be determined. The masses of the intact chains serve to validate the determined sequences. The light chain sequence must match within a +/- 1.2 Da range. For the heavy chain +/- 1.8 Da are allowed. If the determined sequences do not match with the protein mass, you will not be charged.
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Human acute myelogenous leukemia (AML) is highly heterogeneous and, as demonstrated by this group, exhibits significant variability in sphingoiipid metabolism. Current therapy of AML is highly toxic, yielding ultimately inadequate outcomes for the vast majority of patients. Cell lines are limited in their representation of primary AML subtypes and manifest clonal evolution in culture, suggesting limitations in their relationship to the primary case material. The systematic study of these diseases thus requires access to primary samples representing a substantial pool of cases, and correlation of these samples to clinical data including treatment outcomes. Animal models of various kinds are available, but models representing direct leukemogenesis via expression of relevant oncogenic proteins and immunodeficient xenografts propagating primary AML, provide relevant platforms for studying developing therapies. In this Core, materials and models will be provided to each Project to allow completion of proposed objectives. The following specific aims will be pursued:
Specific Aim 1 : Expand and maintain the PSHCI leukemia cell bank to provide programmatic access to cell and plasma samples from a broad variety of AML patients and normal hematopoietic controls. Samples will be cryopreserved in multiple aliquots to allow repeated interrogation via developing technologies. Clinical data will be collected and available to provide biologically meaningful categorization of AMLs.
Specific Aim 2 : Develop and maintain a menu of animal models in which to test promising program-derived therapies. Two such models are available.
Sub aim 2 A: Xenograft models of primary human leukemia have been developed in N0D/SCID/IL2ry (NSG) murine hosts and used as platforms for testing novel therapies. Multiple lines (originating from multiple AMLs of differing subtypes) will be passaged in NSG animals to provide in vivo validation of therapeutics. Human cord blood will be expanded in NSG mice to provide normal controls for in vivo toxicity studies.
Sub aim 2 B: Murine syngeneic models of AML using retroviral transduction of murine bone marrow cells with fusion protein oncogenes. We have established a MLL-AF9 retroviral transduction model, which develops a stem cell derived leukemia shown to be inhibited by Project-derived therapeutics. This Core is essential to the overall Program, each project of which uses primary, cells and in vivo models as provided here. These materials and testing platforms will allow development of novel therapies for these lethal diseases.
The overall goals of the present project are to study sphingoiipid metabolism in AML, and to design novel sphingolipid-based therapeutics for the treatment of AML. This Core will serve an essential role for all projects by maintaining a repository of human AML samples with defined clinical outcomes, as well as by developing robust murine models to test the efficacy of the project's sphingolipid-based AML therapeutics.