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Welcome To The Bicycle Accidents Lawsuit Center
Thanks for stopping by. First, let us introduce our lead counsel. Michael Ehline, of Ehline Law Firm PC, has actively led the way in aiding victims of bicycling accidents.
Bicycling is a commonplace form of portage, amusement and fitness from one end to the other in California State. Bicycles afford very limited protection from the day to day perils facing bicyclists on the roadways of the Golden State. Riding bikes can, and often does, pave the way to moderate injuries to riders on the low range, to severe harm and loss of life on the high range. The catastrophic injuries to bicyclists from roadway accidents are tragically higher among kids, and school aged children. Victims of bicycle smash ups face unique challenges, both medically and legally, when one is trying to get paid by the person(s) who negligently caused these injuries. Plus, under the laws of California and local municipal codes, require riders or their legal representatives to have specialized training and experience concerning the duties, rights and obligations of bicyclists throughout the state.
The vast majority of bicycle accident claims Ehline Law typically faces, comprise of fact patterns where there is contact between riders and passenger care who are guilty of failing to yield the right-of-way at an intersection, such as when a cyclist is cut off by a sudden, un-telegraphed turn by a vehicle directly into the path of an oncoming bicyclist. Typically car drivers , misjudge the speed of the bike, or do not see the bike, and thus, misjudge the safe space they should allocate in order for safe passage. Often, motorists, fail to fairly share the road, or a large vehicle like a bis or truck is not paying attention to smaller objects like bikes in their blind spots. This has forced many a rider into a curb, or onto a sidewalk, or other fixed object, to their doom. This visibility issue is a huge danger to riders.
Bicycle mishaps on roads are also caused based upon other forces, many of them being particular to the utilization of this unique machine used for transportation. Bicycle accidents often happen from or are exacerbated by coincidental factors such as poorly designed roads, negligent repair, signage or maintenance. These factors often lead to limited, or severely impaired vision of the poor road and path conditions. Other negative conditions riders face are things like loos gravel, trash, oil spills, potholes, and other road debris. Riders make easy targets for loose dogs, and many a fallen rider has fallen victim to packs of dogs pulling the down and tearing them to pieces. One of the atypical twists facing California riders, occurs after an unreasonable motorist negligently opens their car door into the path of a bicycle rider. Another stroke of bad luck very common in large cities like Los Angeles, is when person on foot is slammed into by a bicycle delivery service, such as a process server, or legal messenger, and even a food delivery service who hires out riders.
Other Facts About Rider Injuries
In California, bicycle riders are subject to the same obligations and restrictions as cars, except where specifically provided for by law, such as bicycle lanes. In fact, some municipalities allow bikers to ride on the sidewalk, such as parts of Los Angeles. LA County may also allow sidewalk riding, subject to the restrictions laid out in the Vehicle Code here, and County Code here. But as discussed, riders need to obey the rules of the road just like operators of all other traditional motorized conveyances. (See safety tips here). But there is not rule requiring a cyclist to have liability insurance.
Bicyclists under age 18, are also subject to helmet laws codified in California Vehicle Code §21212. In California, a child under the age of four year, or weighing 40 pounds or less, is prohibited from being a passenger on a bicycle unless riding on a seat which holds the child in place, and protects the youngster from moving parts. The child must also wear an approved helmet. (Source CHP "Common Causes of Bicycle Accidents.")
A factor that people need to also comprehend, is that helmets are not designed to stop injuries in all situations. Rider awareness is the key to staying safe. Speeds and impacts of 15 to 20 miles per hour or under, may allow a helmet to lessen or prevent serious head injuries, but not always, and not at all at higher speeds. It is just a safety implement, not a guarantee or insurer of safety. Under U.S. benchmarks, bicycle helmets are tested in 2 meter drops which travel at drops of approximately 14 miles per hour (or 22.5 kph) on a flat, anvil. However, the New England Journal of Medicine said in a notorious piece, that individuals wearing a bicycle helmet had at least an 85% lessened chance of a serious head injury. In fact, it went on to say that there was also an 88% reduced chance in the risk of serious brain injuries. (See also, "A Case-Control Study of the Effectiveness of Bicycle Safety Helmets", Robert S. Thompson, M.D., Frederick P. Rivara, M.D., M.P.H., and Diane C. Thompson, M.S. N Engl J Med 1989; 320:1361-1367, May 25, 1989.)
The experts have concluded that inconsequential skull and brain housing group injuries, typically arise from linear acceleration, wherein the head impacts with another physical barrier to free movement. Wearing a bicycle helmet is known to assist, in prevention and mitigation of serious, or traumatic head injury. This is because a helmet is able to reduce, and spreading the inertia through the device. Alternatively, the greater, and more devastating types of harm, typically arises from angular as well as rotational acceleration. This can result in a diffuse axonal injury (DAI) or even subdural hematoma (SDH). The above, are the standard head injuries afflicted upon unfortunate riders, and have been known to set the stage for loss of life upon spill victims. Bicycle helmets are not engineered to reduce rotational injury, and the available scientific research does not look promising in a helmet's safety capacity improving any time soon. (See also "Curnow WJ. The efficacy of bicycle helmets against brain injury." Accident Analysis and Prevention, 2003,35:287-292.)
Ehline Law Firm PC is a legal advocate, and its attorneys are also riders of all types of cycles. We put ourselves in the shoes of victims and we feel their pain. When victims become our clients, they can take pleasure in the confidence they have that we are fighting to get them a comprehensive financial recovery. We fight for windfall like results. We do this by putting fear in the hearts of the opposition by showing them we are the real deal. We hire the right experts, investigators and legal researchers to seek out the strengths of your case, and the weaknesses in the defendant's case. Let Ehline meticulously prepare your case for settlement, mediation and trial. If you or a wage earner are devastated and feeling the pain of a serious loss or death from a spill on a bike, call us to get a detailed analysis of your potential injuries claims with a real lawyer. (888) 400-9721.


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Results 17 to 21 of 21
Thread: RBI refused information.
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Re: RBI refused information.
I think RBI has not designated Post Offices as ACPIO and hence it is asking for Rs10 through cash, demand draft or postal order. Even all central govt depts have also not designated post offices as ACPIO. List of depts/organisations can be checked on website of post dept: indiapost.gov.in. It is better to pay Rs.10 by cash,bank D.D. or IPO [ipo is cheapest] rather than wasting time and energy in complaining etc, if one is really interested in information.
› Find content similar to: RBI refused information.
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Re: RBI refused information.
I think RBI has not designated Post Offices as ACPIO
There might be some ambiguity in using the Postal Route(u/s 6.3). But it has been accepted norm now for a lot of Central Public Authorities including RBI.
The CIC has been very explicit on this. So the RBI has also amended it's ways accordingly. Apart from that single issue, there is absolutely no refusal from RBI to any of my queries. That was a freak incident, I suppose.
Somehow I am lucky with RBI, because till date I never paid anything to RBI for any information supplied by them.
Sec. 7(6) effect ! !
P.S. Your suggestion for IPO is very much pertinent and should be used invariably.
Re: RBI refused information.
RBI has not designated Post Offices as ACPIO.
This provision is in-built in sec. 6(3).
In my above complaint case the RBI has submitted a letter (issued by Dept. of post) before the CIC saying that UCR / ACG-67 are only for internal use only. i.e. use of UCR/ACG is restricted for use by Dept. of post only.
Although RBI has grudgingly accepted that they will honor UCRs/ACGs henceforth.
UCRs/ACG-67 cannot be used for other Public Authorities.
This letter is signed by a senior officer of the Dept. of Post.
Is this contention right?
Last edited by sidmis; 06-06-08 at 11:22 AM.
Re: RBI refused information.
I have uploaded that file for the members to see and comment.
I will email this page to those members who have difficulties in viewing this image here.
Last edited by sidmis; 06-06-08 at 01:02 PM.
06-06-08, 07:01 PM #21Helpful Member
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Re: RBI refused information.
Yes the contents are correct and in order.
But that does not stop one from filing RTI Application through the APIO Post Office Route. Meaning, even if you wish to file an RTI Application with another Public Authority, say Min. of Parliamentary Affairs, you can still submit your RTI Application addressed to the CPIO of Min. of PA, along with ACG-67 / UCR worth Rs. 10/- to the designated APIO Post Office of your city. They will have to forward your application to the concerned CPIO at the earliest.
Lage Raho
Manoj Pai

subset: commoncrawl


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At ERA Kennedy Group REALTORS when you work with one of us you work with all of us. ERA Real Estate was founded on the principle of collaboration- the idea that by working together and helping one another we could build a stronger community of real estate professionals and help to strengthen the communities where we work and practice real estate.
ERA Kennedy Group Realtors
Keep up to date on all our news, get tips, and more.


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Rates in USD (taxes & fees included), shown as:
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US$136 Avg. price/night
Bulleigh Barton Manor
Ipplepen, Newton Abbot TQ12 5UA, United Kingdom
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Check-in: 16:00
Check-out: 10:30
Enjoy your visit to Newton Abbot with a stay at Bulleigh Barton Manor. Guests can take a dip in the outdoor pool, and free perks include English breakfast and self parking.
Ipplepen Newton Abbot TQ12 5UA, United Kingdom


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Home > Company Profile
Guangzhou Aoqun Brush Industry Co., Ltd.
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The supplier's company premises has been checked by Alibaba.com staff to ensure onsite operations exist there. A third-party verification company has confirmed the legal status of the supplier.
|Business Type:
|Manufacturer, Trading Company
|Guangdong, China (Mainland)
|Main Products:
|Brush (Escalator Deflector Brush,Door Airproof Brush,Door and Window Energy-Saving Brush,Cleaning Brush,Industrial Brush)
|Total Employees:
|Fewer than 5 People
|Total Annual Revenue:
|US$5 Million - US$10 Million
|Year Established:
|Top 3 Markets:
|Domestic Market 13.62% Northern Europe 10.91% Western Europe 10.61%
|Business License,Test Reprot,Test Report,Test Report,Test Report,Test Report,Test Report,Test Report
Guangzhou Aoqun Brush Industry Co., Ltd is a comprehensive research and development, production, sal...
Guangzhou Aoqun Brush Industry Co., Ltd is a comprehensive research and development, production, sales and service in a body's specialized brush enterprise.
Aoqun brush have strip brush\roller brush\clean brush and tube brush have cylinder-shaped\conical\oval. The products has been exported to abroad, and operates in more than 50 countries and regions in the world. Products are widely used in doors and windows, furniture, hardware, glass, ceramics, textile, cabinets, high-speed elevator and environmental protection, breeding, cleaning, etc. To achieving seal ,dustproof, windproof, sound insulation, heat and cold insulation, energy saving insulation, such as polishing, grinding, cleaning filter effect. On the other hand, Aoqun brush have flame retardant, anti-static, static conducting and other functions , also can provide all kinds of brush products series of accessories.
Aoqun Company has the production process, equipment and advanced high-quality talent, on the other hand, Aoqun Company pay attention to quality and safety, according to the ISO9001 to establish the quality management system and obtained CNAS and IAF authorized certification, also obtained the standardization of safety production enterprise certification. Aoqun Company will always insist on the tenet of "sincerity for trust, achievement future" and "create customer satisfaction products" as the enterprise spirit. Adhere to the scientific management, strict requirements, creating the world's leading brush enterprises, contributing more power to "China create".
Trade Capacity View More >
Trade & Market
|Main Markets
|Total Revenue(%)
|Domestic Market
|Northern Europe
|Western Europe
|Southeast Asia
|Mid East
|South Asia
|South America
|Eastern Asia
|Southern Europe
|Eastern Europe
|North America
|Export Percentage:
|81% - 90%
|Export Mode:
|Using an agent
|No. of Employees in Trade Department:
|6-10 People
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- Company Overview
- Company Introduction
- Company Capability
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- Ed and Eddy's prank at the gag factory. RUN DOUBLE D!!!
Ed: If looks could kill, I'd be dead.
- While the punishments from the kids onto the Eds usually leave them cowering in fear, the fact that all three of them are panicking and trying to run for their lives, visibly scared the whole time at the start of The Movie is unsettling; especially with the kids actually pissed off enough to try and murder them.
- The kids' injuries are also pretty freaky. Jonny has a bear trap on his head, Kevin looks like he was set on fire, Nazz's hair has been partially shaved off and she's naked in a magician's box, and Rolf has most of his torso torn off! What the FUCK did the Eds do?!
- The Ed's scenes of panic are all uncomfortable to watch in their own way. Ed is acting like they've caused The End of the World as We Know It, Edd is writing a letter to his parents saying they've done the most unholy sin imaginable and has to keep pausing to cry, and Eddy is down right hysterical.
- A Reddit user posted a theory he calls The Scam That Went Too Far. It's not pretty.
- Towards the end of the movie, Kevin states the Eds have to "pay with their lives", which means that at least he was going to actually commit murder.
- Doubles as Fridge Horror, as Kevin now hated the Eds enough that getting life in prison or the death penalty would be worth it.
- Or the fact he thinks it's okay to murder three guys who he should know have families (that are hardly there for them anyway, but Kevin still didn't seem to care either way).
- The scene where Eddy and Ed seemingly sink in quicksand/mud, even though it's only a prank, it was surprisingly close to an actual death scene.
Ed: "The evil dark side has consumed them both! Trouble! Bad! Pain!"
- Double D's reaction to them faking their deaths. He is extremely pissed at them for scaring him that much. Sure he got mad in the main show, but here he is legitimately pissed off at them to the point of which he's willing to go back to the Cul-De-Sac rather than spend another second with Eddy and that he actually gets into a fight with Eddy over the scams, and the two actually physically duke it out. What makes it worse is that Ed watches the entire scene in utter fear and he's powerless to do anything about his two best friends fighting.
- Eddy's brother in general, and particularly the smile and stare he makes (pictured above). It stretches to around half his face. Worse, he's an Ax-Crazy Psychopathic Manchild who loves torturing children, and the only one in the series that really deserves these tropes. His Evil Laugh when he twists Eddy's leg as well. It's not a comical laugh, but a realistic, twisted, demented laugh. Even the music that plays during the scene is pretty freaky too, as it is a sinister tune mixed with an electric guitar. Listen to it here.
- The kids all react in absolute horror, to the point that Kevin, of all people, gets over his fear of Eddy's Brother and tells him to lay off.
- The way Eddy brokenly begs for his brother to stop beating him is extremely unsettling.
- Even the Kankers are utterly appalled by his cruelty.
- The worst part? Eddy's Brother's entire reasoning (at least from what we saw) of why he torments Eddy? "Belittle?! He's always been little!". Makes it more disturbing since some abuses don't ever give a reason for harming others.
- When Rolf thinks he's found the Eds, he takes out a pitchfork and starts stabbing the air.
- The look on Ed's face as he decides to let the door off its hinges looks frighteningly familiar to the Nightmare Face he made back in "Little Ed Blue".
- What's worse is that Ed was doing that out of his free will, whereas in Little Ed Blue, he was under the influence of a pebble within his shoe. It's disturbing to know how far Ed's state of mind is willing to go if he's pissed enough.


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Twitter advertising includes conversion tracking and re-marketing tools.
AdRoll is a simple and effective platform for advertising online and retargeting previous website visitors to bring them back to your site.
Facebook Retargeting Pixel
Foursixty turns your brand and customer generated content into shoppable galleries for your online store.
Website using the £ symbol on their website - meaning it may accept payment in this British currency.
Shopify is a powerful ecommerce website solution that allows you to sell online by providing everything you need to create an online store.
Shopify Plus is an enterprise eCommerce software solution from Shopify Inc.
Nosto enables online retailers to deliver their customers a personalized shopping experience.
Simple, fast, and powerful. Optimizely is a dramatically easier way for you to improve your website through A/B testing. Create an experiment in minutes with our easy-to-use visual interface with absolutely no coding or engineering required. Convert your website visitors into customers and earn more revenue today!
Websites using some type of Facebook technology.
Website using Instagram integrations or links.
Facebook Connect allow users to connect their Facebook identity, friends and, privacy to any website. Facebook Connect is Facebook's first attempt to allow access to Facebook user data outside of Facebook itself. The company is describing it as giving third party applications access to much of the same data as Facebook applicat...
Website with links to Instagram profiles or pictures
All Twitter's social tools, including buttons and timeline widgets.
AddThis, the new brand name for Clearspring Technologies, is the leader in socially connecting publishers, services and advertisers to audiences on the open web. Reaching more than 1.3 billion unique users monthly, AddThis' social tools and analytics are used on more than 14 million unique domains to distribute and track digital...
iOS Safari instructions for mobile web apps
This site uses the viewport meta tag which means the content may be optimized for mobile content.
Disqus is a networked community platform, reaching over 900 million people a month, 1.8 million registered communities, and over 300M active commenters. The service offers a networked comment system used to foster engagement and connect audiences from around the web. Disqus looks to make it very easy and rewarding for people ...
nginx [engine x] is a HTTP server and mail proxy server written by Igor Sysoev.
The Platform for Privacy Preferences Project (P3P) enables Websites to express their privacy practices in a standard format that can be retrieved automatically and interpreted easily by user agents. P3P user agents will allow users to be informed of site practices (in both machine- and human-readable formats) and to automate dec...
The DOCTYPE is a required preamble for HTML5 websites.
Allows a website to define how a page is rendered in Internet Explorer 8, allowing a website to decide to use IE7 style rendering over IE8 rendering.
Content Security Policy is best used as defense-in-depth, to reduce the harm caused by content injection attacks.
Open graph type entity tag
Open graph url entity tag
Open graph description entity tag
The Open Graph protocol enables any web page to become a rich object in a social graph, a open protocol supported by Facebook
Open graph image entity tag
Open graph title entity tag
Open graph site name entity tag
Any offered product or service. For example: a pair of shoes; a concert ticket; the rental of a car; a haircut; or an episode of a TV show streamed online.
Meta descriptions are HTML attributes that provide concise explanations of the contents of web pages. Meta descriptions are commonly used on search engine result pages (SERPs) to display preview snippets for a given page.
Sites who has this tag are verfied by google to use WebMaster tools
The http-equiv attribute provides an HTTP header for the information/value of the content attribute. The http-equiv attribute can be used to simulate an HTTP response header.
A canonical link element is an HTML element that helps webmasters prevent duplicate content issues by specifying the "canonical", or "preferred".
UTF-8 (8-bit UCS/Unicode Transformation Format) is a variable-length character encoding for Unicode. It is the preferred encoding for web pages.


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Mobile-Centric Computing: How Mobile Devices, Apps Are Creating a New Web
NEWS ANALYSIS: The world is shifting from a Web-centric one to one based on mobile-centric IT. Right now, smartphones, tablets and mobile apps are leading the way.Are you aware that we're creating another Internet? It's one that is mobile-centric rather than Web-centric, and it's going to continue and become more important in the years to come. The reason that a good part of the Web is being recreated right before our eyes is summed up in one word: mobile.
If you use a mobile Web browser on your smartphone and enter a traditional Website, the experience is less than positive. Most of the time, it's just plain awful. That's because normal Websites are not meant to be viewed on tiny screens using smartphones.
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|Property type
|Minimum Stay
|3 nights
Relax….Enjoy…. Savor…. this charming and cozy beach casita with private ocean patio and amazing views of the Atlantic Ocean and the mountains . The best beach at your feet - the famous Luquillo beach. Located at the most private spot of the beach, close to all amenities to make your wishes come true. Go snorkeling or scuba diving steps away from your patio, ride the waves at sunset a short walk away, play beach volley ball, or just stroll peacefully on this magnificent beach. If water sports are not your cup of tea, just relax in the comfort of this casita, bask in the sun and let the ocean breeze overtake you.
Close to EL YUNQUE NATIONAL FOREST, with miles of hiking trails and refreshing river ponds and the town of Fajardo, famous for its sailing. Chartered sailing trips to unspoiled little islands close distance offshore, kayak trips to the bioluminescent bay and tours to Las Cabezas Natural Reserve are located in this town.
There are four resorts with professional golf courses and tennis courts within 15 minutes ride from the casita. For adventure lovers, 5 minutes away is Hacienda Carabali, providing horseback riding, ATV rides, go Karts and wonderful local cuisine.
Old San Juan is a must see, just 40 miles away. Old world charm and elite shopping await you.
The casita is located very close to the airport (only 36 miles away) in a small beach development, Poza del Mar, consisting of just 15 units. It provides accommodation for 8 persons and is wheelchair accessible from the parking lot. With 1,500 square feet of living space, it has two bedrooms - Master with en suite bathroom, king size bed and double louvered casement windows that open to a wonderful ocean view, Guest room with queen size bed with side bathroom and there are two very comfortable full futons. Choose from air conditioners, ceiling fans or the natural ocean breeze. All indoor and outdoor furniture is new. This casita has just been put in the market for your enjoyment. It has two great terraces and a big, ocean front beach patio to relax outdoors, with loungers, hammock and outdoor table with sitting for six. Inside, it has a comfortable kitchen with new equipment and a lovely dining area that accommodates six people, both with gorgeous ocean views. The living room is charming and inviting with comfortable seats and of course, great ocean views. Free Wi-Fi is available. Ipod-Ipad speaker station, snorkeling gear, small wave boards, paddle boards, volley ball, beach toys, beach chairs and towels are provided. . Pet friendly.
The charm of this Casita and the beauty of this ocean awaits you.
This beach front casita is a must stay in Puerto Rico. The beach is right out your door and is a great beach for young children with the water being only knee deep with little tidal waves. The views from the balconies are wonderful. The property manager, Rosa is so helpful - she even had the gardener trim bushes off the patio at our request so we could sit and look out on the beach. We highly recommend staying here in your next visit to Luquillo.
This property is a must stay. My girlfriend and another couple stayed here for 5 days 4 nights and I have to say this is my favorite property in all the years I've been coming to PR. The view from the master bedroom and back terrace is incredible. Everything we needed was a short drive away. Rosa, the property manager was amazing, She was available every time I called. I can't really say anything bad about this property. I will no questions ask will be staying in this house again. Thanks Rosa for everything
We got in late Saturday night, and Rosa was so sweet, she stayed up to meet us and give us the keys to the condo. Once on our way, we did have difficulty finding the property. There wasn't an actual address or name of the complex given. However, we immediately called Rosa and she talked us thru and stayed with us on the phone until we found it. Condo is very secure, you have to have keys and remote controls to get thru all entrances/exits.
Once in the condo, we were very pleased to find it very spacious and updated. As the previous reviewers stated...it does need a few cosmetic repairs, but they are all minor. We actually found the sofas in the living room comfortable. The bedding in the master bedroom does need some upgrading...but I've slept on a lot worse! Loved opening the windows and feeling the breeze and hearing the ocean. We felt right at home the whole time! We spent quite a bit of time on the beautiful patio watching the ocean.
The condo is located in a very central location for us. We are on the ocean, within 1/4 mile of the beautiful Luquillo Beach and the Kiosks. Short driving distance to Fajardo, the Yunque Rainforest and San Juan. Perfect location for anyone wanting to experience everything Puerto Rico has to offer.
I would recommend this condo to anyone! We can't wait to come back!
The pros on this condo far outweigh any small negatives. Rosa was amazing and the most helpful and responsive person I've ever dealt with on any rental. The condo has a very nice layout and the rooms are large. Kitchen was well-appointed with cookware and everything needed and having a washer and dryer very convenient. Patio was very comfortable and private. It is right on the beach and close to the Kioskas where there are several great restaurants to choose from. Beautiful walking beach and nice to sit on as well. The surf was very strong near the property while we were there so for swimming would have walked down the beach a little where there was a very pretty and quiet swimming area.
We didn't find the futon sofa/sleepers in the living room as comfortable for sitting as a regular sofa would have been (we did not use them for sleeping). The bedding in the MBR could use freshening and updating and some paint and trim touch ups would go a ways to just bring it up to a 5 star for me. Also, regular beach chairs would have been nice rather than the higher sports chairs supplied which are fine for watching a game at a field but not great for sitting on the beach.
Thank you, Rosa, for such great service and flexibility. We would definitely stay here again.
This was a beautifully maintained condo in a great location. You could walk down the beach in both directions for what seemed like miles if the tide was out. The beach right in front of the condo is shallow and there is a reef, but just a short walk in either direction there were deeper beaches for swimming, boogie boarding, collecting shells etc. Be sure to have bug spray on the beach at night or early in the morning bites from sand fleas (which we found out are on most beaches in the tropics) itch like crazy. The condo is in a gated community, very quiet and secure. There were beach chairs, an umbrella, snorkels/goggles, and boogie boards at the condo to use, among lots of other things. The Kioskos in Luquillo are a must for good food. El Yunque Rain Forest was only about 10 minutes away. Rosa was very kind and helpful. We would love to come back and stay again!
It was a wonderful place for our Christmas vacations, we have two boys both under 3 years old and the beach and water were perfect for them, within walking distance you can find deeper crystalline water for adult swimming, infront of the property the water is shallow but great for the kids. We loved our stay, the property was clean and it had everything we needed to feel like home.
Amazing amenities , from the magnificent El Yunque National Reserve, the bioluminescent bay in Fajardo, sailing to pristine islands at the shore front of Fajardo, snorkeling or scuba diving
at the reefs right in front of the property, Horseback , ATV or Go-Karts rides at Hacienda Carabali, elite shopping, golf and tennis.
|Rate Period
|Weekend Night
My Standard Rate
3 night minimum stay
|Pet Fee
|Refundable damage deposit
|Tax Rate
The quality of the accommodations, the emphasis on the details and service will
exceed your expectations.
Fifty percent (50%) of total rent fee is due with reservation. Remaining balance, Security Deposit and cleaning fee is due 30 day prior Check In date. Payment is accepted US Dollars via PayPal . Rates are subject to change until reservation is confirmed. The rent applies up to 6 persons. Extra person charge is $25.00 per night. BBQ Cleaning when is left dirty $50.00. Pet fee $25.00 per night.


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KONA NIGHTS (J. T. Aitken, R. 1992), Sdlg. 82M107. BB, 26"
(66 cm), M "S. light violet; F. deep velvety purple black, edged lighter;
beards dark.
Hellcat X TA79-80: ((Warm Laughter x Dusky
Evening) x Mystique).
Aitken's Salmon Creek 1992 HM 1994"
It has lost it's fat beards in the process, and is
less blue.
I'd like to see it back crossed with Hell
But i can't do them all, and since i've decided for
rebloomers, i must focus , and stick to it!
So i'd better cross it with Best Bet !
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Kidstar, Menu Service (Manufacturers), listed under "Menu Service (Manufacturers)" category, is located at 207 Yuma St Denver CO, 80223 and can be reached by 3039340004 phone number. Kidstar has currently 0 reviews.This business profile is not yet claimed, and if you are the owner, claim your business profile for free. If you are not the owner you can invite this business to join by email or by phone.Browse all Menu Service (Manufacturers) in Denver CO. Discover census data for Denver, CO.
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Rice Ring with Creamed Vegetables
|2 Cup (32 tbs)
|3⁄4 Teaspoon
|1 Cup (16 tbs) (not quick cooking type)
|Grated nutmeg
|1⁄4 Teaspoon
|Coarsely chopped blanched almonds
|3⁄4 Cup (12 tbs)
|1⁄4 Cup (4 tbs)
|2 Cup (32 tbs) (creamed or buttered)
Bring water to rolling boil; add salt, then rice.
Cover, let come to high boil again, reduce heat and simmer 20-30 minutes, removing cover last 5 minutes and shaking pan to separate grains.
Season with nutmeg.
Grease a 7-inch ring mold generously, and sprinkle bottom with almonds.
Press in the rice.
Melt butter or margarine, and pour over mold.
Set mold in pan of hot water, and bake 20 minutes at 350°F.
Loosen edges, invert on platter and fill center with vegetables.
Recipe Summary
Rate It
Nutrition Rank
Nutrition Facts
Serving size
Calories 375 Calories from Fat 205
% Daily Value*
Total Fat 22 g34.5%
Saturated Fat 5.9 g29.6%
Trans Fat 0 g
Cholesterol 20.2 mg6.7%
Sodium 268.3 mg11.2%
Total Carbohydrates 37 g12.4%
Dietary Fiber 5.3 g21.2%
Sugars 1.1 g
Protein 11 g21.2%
Vitamin A 55.5% Vitamin C 8.7%
Calcium 10% Iron 9.4%
*Based on a 2000 Calorie diet


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- 512MB 256-Bit GDDR3
- Core Clock 600 MHz
- 2 x DVI
- 112 CUDA Cores
- PCI Express 2.0 x16
Nice card 06/02/2008
This review is from: EVGA GeForce 8800 GT DirectX 10 512-P3-N800-AR 512MB 256-Bit GDDR3 PCI Express 2.0 x16 HDCP Ready SLI Support Video Card
duel slot, bigger fan than single one. bought it around 180 and have a 50 MIR (= 130), good prize. and over clocking is fantastic.
GPU temp can't go down lower. fan speed to 100%, the temps kinda like 52C. but not a big deal.
Other Thoughts:
set fan speed to 80%, clock it to 750Mhz. and got a 11419 for 3dmark06. not bad at all. i will buy one more later my life for SLi,
1 people found this review helpful. Did you? Yes / No Thanks for the valuable feedback you provided!


text: Reliving Pearl Street's Past Back to Article Comments Need to Register? X Remember Me Forgot your password? Latest local news Bridge City still waiting for OK for water filtration system 4 arrested in Beaumont in robbery conspiracy Mardi Gras of Southeast Texas kicks off in downtown Port Arthur Appeals court affirms dismissal in Sheriff's deputies' tampering case Police: Vidor teen dismembered his own hand


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Food Alert Limited
food, health and safety training, fire safety training
To provide delegates with a fundamental knowledge of safe work practices and the skills to monitor safe and healthy working environments.
Who Should Attend?
All staff who have not received formal training in Health and Safety.
Creating a healthier and safer working environment
Reduces the risk of accidents and injuries
Course Structure:
The two hour training course includes lectures enhanced by audio/visual material and practical teaching aids. Delegates are encouraged to actively participate in discussion sessions and group activities.
Course Content:
General Health and Safety
Manual Handling
Fire Safety
The course culminates with a short examination which comprises of 14 multiple choice questions. Successful candidates receive a certificate from Food Alert.
Print this page
Suitable for anyone working within retail organisations that serve alcohol to the public, who need to be aware of their
This course provides students with an understanding of the impact of our daily life on the environment. Course Topics:
Suitable for a variety of candidates, this course provides students with the skills and knowledge to deal with first-aid
This qualification will prepare employees to contribute to the safer use of hazardous substances in co-operation with their managers and
This course is designed to complement the CIEH Level 2 Award in Manual Handling - Principles and Practice. This
To provide delegates with a fundamental knowledge of safe work practices and the skills to monitor safe and healthy
Designed to make candidates aware of the key health and safety issues and the part that they should play
To provide food handlers with an appreciation of the fundamentals of good food hygiene practice and to equip them
This qualification has been developed to raise awareness of key food safety issues and to provide employees with an
With current public global interest and the requirements of owners and investors, the need for businesses to address environmental
To provide Managers with an update on current food hygiene and health & safety issues. This should enable them
Delegates who successfully complete this course and apply for approval as tutors to conduct the Formal Level 1, i.e. Foundation
To provide delegates with a fundamental knowledge of fire safety and of the specific duties and responsibilities as a
To provide candidates with a appreciation of the fundamentals of first aid. Who Should attend? Anyone who may be
The objective of the Chartered Institute of Environmental Health's Level 4 Award in Health and Safety is to provide
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Page 3 Archives for February 2006
This clip took place on April Fools of last year. Just before the race began one of the jockeys thought it would be funny to put a couple of heavy duty springs underneath this guys saddle.
Buffalo Wild Wings' Spicy Garlic stings. Just how much sting? Check it out.
The guy in this clip is tryin to beat the record set two weeks ago for distance thrown from a car while being chased down by the cops. He falls short of the title but luckily had his coffee in the cupholder which ended up being just enough weight to keep the car from rolling on top of him.
Watch this dad play a nasty prank on his kid. The kids reaction is hilarious, he just got a diaper full of poo to the face.
I totally relate to this guy. I dont know how many times I have done everything I could to help someone and in the end I always get jabbed in the back. Granted this guy had a truck hit him in the back but regardless it just goes to show once again No Good Deed Goes Unpunished. I just hope there are enough of us out there that never learn the lesson.
Alright, who do you guys think hit the ground harder? The first guy did come down pretty fast but at least had the luxury of rolling down the hill while this dude just bounced off the grass. Actually, after watching the first video again roll is kinda used a bit loosely there. My money is on the first guy.
Got to give the guy credit. This is a pretty sweet stunt. Great takeoff and nice positioning in mid-air. Although, if he would have nailed the landing we wouldnt of posted the clip.
This guy is casually robbing a cash register at a supermarket. Out of nowhere a guy whacks him in the back of the head with a metal pipe knocking him out cold.
No chance this was going to work. This kid runs up to a snowboard and tries to ride the stairs down.
This is close. Which one of these two guys do you think slapped harder. I call it a draw.
This is great montage of snow board crashes from our friend Trailer Tom. Crashing should be an Olympic event. I would definitely watch that.
This is a really heartwarming story of an autistic high school student who scored 20 points in a recent game and became the hero of his town. I just read that after this happened hes gotten countless offers from Hollywood to make a movie about his life.
Talk about adding insult to injury. Its not enough that he misses the jump completely but while hes down the table comes crashing down on top of him.
Bill Dance Outdoors fishing show. This guy just cant catch a break or a fish for that matter.


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Wego.com.sg recently found 14 hotels in Bruchsal, Germany. Find a range of accommodation in Bruchsal at great prices. Book luxury Bruchsal hotels or find last minute accommodation. Save more on cheap hotels in Bruchsal with affordable room rates.
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Fabtech K4009 Crawler System
View Additional Required Parts »
Fabtech K4009 Crawler System w/Performance Shocks - 8 in. Lift
See Full List of Vehicle Applications »
Fabtech - Crawler System P/N K4009 Features:
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Wrangler (LJ), Jeep, 2006, 2005, 2004
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Welcome to The World Federation Against Drugs
George: "I was a street child myself"
George Ochieng Odalo, 28 years old, social worker from Kenya and the founder of Slum Child Foundation.
As a street child in the slums of Nairobi George met the same reality that he meets today and felt the same feelings.
- I became a street child when my father died. But I survived; someone saw my potential and introduced me to a person who paid for my schooling.
In 2008 George founded the Slum Child Foundation, a nonprofit organization that works with street children in Nairobi. More
Voices from the 4th World Forum Against Drugs
Rima Saade Turk, 48 years, Secretary General at Nusroto Association, drug and rehabilitation center, Cenacle of the Son of Man, Lebanon
Why are you here?
I am here because my organization is member of the World Federation Against Drugs and because I am nominated to be the representative of Asia in the board of WFAD. I want to share experiences with other grass-root organizations and I want to increase our knowledge on drugs and treatment. More
WFAD Release in response to The Report of the West African Commission on Drugs urging West African Countries to Decriminalize/Legalize Drugs
A Report titled, "Not Just in transit Drugs, the State and Society in West Africa" prepared by a group of ex-public servants and some Civil Society activists under the auspices of the West African Commission on Drugs (WACD) has been brought to the notice of the World Federation Against Drugs (WFAD).
After perusing the said Report, WFAD wishes to highlight the following facts pertinent to the Report with a view towards putting the intention and objectives of its sponsors and originators in proper perspective. More
Statement of the Congress of World Federation Against Drugs
Please select a country
Intervention at the intersessional meeting of the Commission on Narcotic Drugs
Open letter to the Mayor of Stockholm
Open letter to:
Karin Wanngård - Mayor of Stockholm
Åsa Lindhagen - Chair, Committee of Social welfare, Stockholm
Sara Pettigrew - Board member of ECAD, representing Stockholm
Regarding Stockholms discussion to leave ECAD
The signatories of this letter are concerned over the fact that Stockholm is considering leaving European Cities Against Drugs (ECAD), an organization it founded. We have been...[Continue]
Action. Now. That will make a difference.
A position paper in support of a balanced and effective drug policy towards 2019
The agenda for the meetings, as well as the proposed outcome document and the list of side events can be found here. The discussion will be broadcasted so it is possible to follow it live here.
The Civil Society Task Force, CSTF, will host a Civil Society Forum the day before...[Continue]
Written statement, 59th Session of the Commission of Narcotic Drugs
Member Activity
COYPED Wants Sustainable Rehabilitation Program for Substance Users in Liberia
Written by: Linda Nilsson
Statement from Swedish Narcotics Officers Association
Written by: Linda Nilsson
Thank you Mr Chairman,
My name is Mika Jörnelius and I work as a police officer in Sweden and I am here to represent Swedish Narcotic Officers Association. SNOA.
Written by: Linda Nilsson
Lead Guest Editor - Ikenna Molobe, Co-founder/Director, Unified Initiative for a Drug-Free Nigeria (UIFDFN)
Drug and substance abuse is a global health problem. The global situation of drug abuse reveals that the problem has become a major source of concern. The dearth of research in drug abuse and addiction is also...[Continue]
The 2016 Nairobi AidEx Conference and Other Soberlife Outreaches
Written by: Linda Nilsson
Voices from African Youth - protect the future
Written by: Linda Nilsson


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> Donald, that triangle bed is where I was thinking about trying your sand method for AB's.
That should work very well. It might be good to retry some of those that didn't survive to see if it makes a difference in survival.
Everytime I look at your photos I find myself trying to visualize what it must look like in your garden space with them blooming. It's so very, very different than my own space and conditions for growing things. Very beautiful. I hope you're having a banner year! Am enjoying the photos a lot.


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Scotch Shortbread
|1 Cup (16 tbs) (At Room Temperature)
|Confectioners sugar
|1⁄2 Cup (8 tbs)
|Vanilla extract
|1 Teaspoon
|Unbleached flour
|2 Cup (32 tbs)
|1⁄4 Teaspoon
|Baking powder
|1⁄4 Teaspoon
Preheat oven to 375° F.
In a mixing bowl, cream butter and sugar together until fluffy. Add vanilla extract.
In a separate bowl, combine flour, salt and baking powder. Add to creamed mixture and mix thoroughly, using a heavy beater or wooden spoon.
Place dough on a lightly greased cookie sheet and roll out to 1/3-inch thickness. If necessary, sprinkle top of dough with a little flour to prevent sticking. Prick holes in top with a fork.
Bake for 20 minutes or until golden. Remove from oven and slice into squares while still hot. If the center portion needs more baking, remove outer pieces and return center portion to oven for a few more minutes.
Recipe Summary
Rate It
Nutrition Rank
Nutrition Facts
Serving size: Complete recipe
Calories 2851 Calories from Fat 1626
% Daily Value*
Total Fat 185 g284.8%
Saturated Fat 116 g580%
Trans Fat 0 g
Cholesterol 483.8 mg161.3%
Sodium 613.7 mg25.6%
Total Carbohydrates 267 g89%
Dietary Fiber 7.3 g29.2%
Sugars 59.5 g
Protein 30 g59.6%
Vitamin A 112.5% Vitamin C
Calcium 18.7% Iron 70.7%
*Based on a 2000 Calorie diet


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Kee Wee (Kee Kee) is a brown tabby w/ white DSH and is a polydactal which means he has extra toes. Actually his front paws look like baseball mits. He is super sweet and loving. He is a big ole' lap cat. Loves dogs and any human. He let's my 9 month old pull out his fur and doesn't care how rough he is. He won't leave him alone. Kee Kee would be a perfect therapy cat. He let's you do anything to him and just loves people. Purrs through everything.
Kee Wee is located in Lakeland FL. Contact Angie at firstname.lastname@example.com.
MCR adoption fees are:
• $200 - kittens spayed & neutered, $150 if too young to spay/neuter with Prepaid S/N Agreement
• $175 - adults 1 - 9 years
• $150 - seniors 10 years and older
• $150 - cats with special needs (any age)
• $150 – Purebred Maine Coon Senior (11 years and older)
• $250 – Purebred Maine Coon (adults 7 - 10 years)
• $300 – Purebred Maine Coon (adults 1 - 6 years)
• $350 – Purebred Maine Coon kitten
• $200 – Purebred Maine Coon without papers (adults 7 – 10 years)
• $250 – Purebred Maine Coon without papers (adults 1 - 6 years)
• $125 – NON Maine Coon (any age)
**We can arrange transport within a reasonable distance for an additional fee.
Adoption fees assist us with shelter fees, testing and vet expenses. It is because of fees that MCR is able to continue with our rescue work.
This usually covers shots, neutering, vet visits and tests,and cost of foster care. Please contact us if you have any questions.
Thank You!
Your message has been sent to Maine Coon Rescue - FL.
You'll receive a copy, too, at to help you keep track of which pets you've inquired about, and which shelters and rescues you've emailed.
NOTE: Some shelters have physical locations you can visit; some of these shelters may only have pets for a limited time, so please do not wait for a reply—just go visit the shelter! Other organizations are rescue groups run by busy volunteers who may take a while to reply. You can find information about the shelter or rescue group caring for this pet, and their adoption procedures, on the pet's details page on Adopt-a-Pet.com.
Contact this Rescue Group about FL - Kee Wee (Kee Kee; CP) again.


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Send several e-mails to"PhotoWraps Customer Service" and responses were slow and now i get no response at all. The canvas prints were intended as anniversary presents for grand parents. I am so disgusted with the way this company was allowed to first change its name and then deny its obligations. order # PHOTO-2858 ordered Nov. 6, 2012 I hope there is a law that prevents companies from committing this fraud. Please let me know if any action... Read more ›
On 10/01/2012 I ordered a 16X20 canvas print of my son who races motorcycles Order #photo2587 (through another ripoff EVERSAVE LOS ANGELES who could care less about my order) Paid $29.00 I figured that I would get it by Christmas as Photowraps had 11 weeks to process my order.When I sent them my first email on 11/11/2012, they sent me their generic *** letter saying"I am very sorry & we received so many orders, that we are a "little backed... Read more ›


text:
Automata, Languages and Programming
Volume 5126 of the series Lecture Notes in Computer Science pp 39-50
Finite Automata, Digraph Connectivity, and Regular Expression Size
- Hermann GruberAffiliated withInstitut für Informatik, Ludwig-Maximilians-Universität München
- , Markus HolzerAffiliated withInstitut für Informatik, Technische Universität München
* Final gross prices may vary according to local VAT.Get Access
Recently lower bounds on the minimum required size for the conversion of deterministic finite automata into regular expressions and on the required size of regular expressions resulting from applying some basic language operations on them, were given by Gelade and Neven [8]. We strengthen and extend these results, obtaining lower bounds that are in part optimal, and, notably, the presented examples are over a binary alphabet, which is best possible. To this end, we develop a different, more versatile lower bound technique that is based on the star height of regular languages. It is known that for a restricted class of regular languages, the star height can be determined from the digraph underlying the transition structure of the minimal finite automaton accepting that language. In this way, star height is tied to cycle rank, a structural complexity measure for digraphs proposed by Eggan and Büchi, which measures the degree of connectivity of directed graphs.
Chapter Metrics
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- Title
- Finite Automata, Digraph Connectivity, and Regular Expression Size
- Book Title
- Automata, Languages and Programming
- Book Subtitle
- 35th International Colloquium, ICALP 2008, Reykjavik, Iceland, July 7-11, 2008, Proceedings, Part II
- Pages
- pp 39-50
- Copyright
- 2008
- 10.1007/978-3-540-70583-3_4
- Print ISBN
- 978-3-540-70582-6
- Online ISBN
- 978-3-540-70583-3
- Series Title
- Lecture Notes in Computer Science
- Series Volume
- 5126
- Series ISSN
- 0302-9743
- Publisher
- Springer Berlin Heidelberg
- Copyright Holder
- Springer-Verlag Berlin Heidelberg
- Additional Links
- Topics
- Industry Sectors
- eBook Packages
- Editors
- Authors
- Hermann Gruber (1)
- Markus Holzer (2)
- Author Affiliations
- 1. Institut für Informatik, Ludwig-Maximilians-Universität München, Oettingenstraße 67, D-80538, München, Germany
- 2. Institut für Informatik, Technische Universität München, Boltzmannstraße 3, D-85748, Garching bei München, Germany
Continue reading...
To view the rest of this content please follow the download PDF link above.


text:
Matt Williamson's projected top three needs for each NFL team provides a good starting point as we prepare for the anticipated start of free agency following the lockout.
I've gone through his chart and culled information with an eye toward the NFC West.
The first chart below reproduces Williamson's projected needs for the division. My thoughts on his thoughts, by team:
Arizona Cardinals: His projected needs and the ordering of those needs line up with my thinking. The needs on the offensive line could be more pressing if Lyle Sendlein and Deuce Lutui hit the market.
Seattle Seahawks: Williamson is not assuming Seattle will re-sign defensive tackle Brandon Mebane. Most of the roster is fluid.
San Francisco 49ers: Aubrayo Franklin's impending free agency explains why nose tackle comes first on the 49ers' need list. Listing receiver as the No. 2 need comes as a mild surprise. Michael Crabtree was the 10th overall choice in 2010. Josh Morgan has been solid and has the blocking ability to fit with the new coaching staff. It's tough to count on Ted Ginn Jr., though, and top-to-bottom quality could use improvement.
St. Louis Rams: Williamson lists running back higher than I would have listed it, but he thinks Steven Jackson is slipping quite a bit. Jackson should be strong enough to carry the load for another season, in my view. The team does need a backup at the position, but starters are needed at defensive tackle and outside linebacker.
Now, on to that chart.
Matt Williamson's NFC West Needs
The second chart combines specific positions into broader positions and then shows how many teams have primary needs at those spots. Nose tackles, defensive ends and defensive tackles become defensive linemen, cornerbacks and safeties become defensive backs, etc.
Williamson lists five teams with primary needs at quarterback: Arizona, Cincinnati, Miami, Seattle and Washington. Tennessee and a couple others could be in the market for a veteran as well, although Williamson sees more glaring needs elsewhere.
This chart shows which positions could be in greatest demand, according to Williamson.


text:
Address: Foreshore Marieville Esplanade, Sandy Bay.
Facilities: Fenced playground equipment, tables and seats.
Find other local parks and things to do in the Bub Hub Pregnancy & Parenting Directory.
Pregnant for the first-time?
Not sure where to start? We can help!
Our Insider Programs for pregnancy first-timers will lead you step-by-step through the 14 Pregnancy Must Dos!


text:
Data Deluge
Researchers Turn to Cloud Computing as Genomic Sequencing Data Threatens to Overwhelm Traditional IT Systems
Seeking Young Scientists for Research in Space
Sounds of Science Podcasts
Infectious Fight
Tackling the Inevitability of Resistance One Genome at a Time
Long Noncoding RNAs: Clarity or Confusion?
Because They Are Such Elusive Prey, lncRNAs Have Yet to Emerge as Therapeutic Targets
Top 20 Biopharma R&D Spenders
Which Companies Have the Deepest Pockets for Research and Development?
Big biopharma still spent big on research and development in 2012, but pharmaceutical and biotechnology giants are divided over how that spending compared with 2011, according to a GEN list of the 20 top R&D spenders for last year (Table).
Five of the top 10 biopharmas, and six of the top 20, spent less on R&D in 2012 than the previous year. Those numbers rise to six of the top 10, and seven of the top 20, when Sanofi is included based on constant exchange rates, which more than wiped out that company's 2.3% increase in R&D expense last year. The declines are not too surprising given talk within the industry of the need to contain costs and generate more return for the money spent on research—in many cases, through new collaborations with other corporate or institutional partners.
The GEN list also shows that 13 of the top 20 biopharma R&D spenders shelled out less for R&D in proportion to their sales than they did in 2008, soon before a wave of mergers and acquisitions helped consolidate the industry's key players—and generated new debt that companies opted to pay down in part via reduced R&D spending.
Of the seven companies that spent more on R&D in proportion to their sales last year compared with 2008, nearly all were either generics giants eager to develop portfolios of branded drugs (Teva), or biotechs looking to expand their product offerings (Gilead), or pharma giants scrambling to replenish pipelines depleted by patent-cliff expirations (AstraZeneca, Bristol-Myers Squibb).
The Table shows a list of the top 20 biopharmas ranked by their R&D spending for 2012. Listings include R&D spending for 2012 and 2011, the percentage difference between the two years, the percentage of sales for both years, and 2008 R&D spending and percentage of sales. Figures were disclosed by the companies in annual reports and quarterly results press releases. Where applicable, figures were converted to U.S. dollars from other currencies.
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One approach to the treatment of neural loss is the transplantation of exogenous progenitor cells. We use a model system developed for neural replacement in the inner ear to investigate requirements for rebuilding a neural circuit: in the current work we study whether transplanted neurons derived from stem cells can restore function to an ear after the loss of primary afferent innervation. Our previous work has shown that neurons from transplanted stem cells can reinnervate hair cells of the organ of Corti after chemical de- afferentation, both in an in vitro explant and in an in vivo gerbil model, suggesting that this neural circuit can be reconstituted in the adult nervous system if appropriate progenitor cells are introduced. In this proposal we use this system to study what characteristics of the donor cells allow them to form functional synapses with hair cells, and we ask whether the new synapses lead to recovery of hearing in animals with primary neuronal degeneration. Understanding the mechanisms underlying re-formation of neural connections to hair cells in the adult ear is important to any therapeutic approach to sensorineural hearing loss.
The Specific Aims comprise 3 inter-related experiments to probe key variables likely to influence the success of hair cell reinnervation by transplanted neural progenitor cells.
In Aim 1 the effect of the stage of differentiation of the stem cells on their capacity to reinnervate hair cells is assessed in a denervated in vitro organ of Corti. Assessments are based on immunohistochemistry: the morphology and number of synapses formed with inner and outer hair cells;and electrophysiology: firing of action potentials and excitatory postsynaptic currents by the neurons after stimulation of hair cells, and inhibition of this synaptic function by pharmacological blockers that inhibit functional activity of native cochlear afferent glutamatergic synapses.
In Aim 2 we use cochlear explants de-afferented by a toxin to study the effect of modulating expression of molecules involved in synaptogenesis. Based on our evidence for their expression in the organ of Corti and their ability to increase synaptogenesis in other systems of neural regeneration, we have selected a group of molecules for study. Semaphorin 3a, repulsive guidance molecule, and semaphorin 4b, a negative regulator of axon guidance and synaptogenesis are inhibited, and neurotrophin-3 and cadherin 11, positive regulators of synaptogenesis are overexpressed. We also inhibit the expression of neuropilin1 and neogenin1, axon guidance receptors expressed in the growth cone of regenerating neurons.
In Aim 3 we build on the in vitro results for in vivo transplantation into a de-afferented gerbil ear, in which the sensory cells are intact but spiral ganglion cells are destroyed. We test whether the reinnervation of hair cells that we have observed in this model results in improvements in functional measures of hearing, and we use a mouse model to study the effect of axonal guidance molecules on reinnervation and functional improvement.
TO PUBLIC HEALTH The work described in this grant will attempt to better understand the genes involved in pathfinding and synapse formation between stem cell-derived neurons and their targets. This information is useful in any treatment in which replacement of neurons could be beneficial. Because of the clear correlation between loss of cochlear cells and sensorineural hearing loss, improvements in our ability to regenerate these neurons and their afferent synapse with hair cells will lead directly to new treatments for loss of hearing.
|Brugeaud, Aurore; Tong, Mingjie; Luo, Li et al. (2014) Inhibition of repulsive guidance molecule, RGMa, increases afferent synapse formation with auditory hair cells. Dev Neurobiol 74:457-66
|Parker, Mark A; Cheng, Yen-fu; Kinouchi, Hikaru et al. (2014) An independent construct for conditional expression of atonal homolog-1. Hum Gene Ther Methods 25:1-13
|Shi, Fuxin; Hu, Lingxiang; Jacques, Bonnie E et al. (2014) ?-Catenin is required for hair-cell differentiation in the cochlea. J Neurosci 34:6470-9
|Yuan, Yasheng; Shi, Fuxin; Yin, Yanbo et al. (2014) Ouabain-induced cochlear nerve degeneration: synaptic loss and plasticity in a mouse model of auditory neuropathy. J Assoc Res Otolaryngol 15:31-43
|Tong, Mingjie; Brugeaud, Aurore; Edge, Albert S B (2013) Regenerated synapses between postnatal hair cells and auditory neurons. J Assoc Res Otolaryngol 14:321-9
|Shi, Fuxin; Hu, Lingxiang; Edge, Albert S B (2013) Generation of hair cells in neonatal mice by *-catenin overexpression in Lgr5-positive cochlear progenitors. Proc Natl Acad Sci U S A 110:13851-6
|Shi, Fuxin; Edge, Albert S B (2013) Prospects for replacement of auditory neurons by stem cells. Hear Res 297:106-12
|Mizutari, Kunio; Fujioka, Masato; Hosoya, Makoto et al. (2013) Notch inhibition induces cochlear hair cell regeneration and recovery of hearing after acoustic trauma. Neuron 77:58-69
|Parker, Mark A; Jiang, Kevin; Kempfle, Judith S et al. (2011) TAK1 expression in the cochlea: a specific marker for adult supporting cells. J Assoc Res Otolaryngol 12:471-83
|Jeon, Sang-Jun; Fujioka, Masato; Kim, Shi-Chan et al. (2011) Notch signaling alters sensory or neuronal cell fate specification of inner ear stem cells. J Neurosci 31:8351-8
Showing the most recent 10 out of 22 publications


text:
The Horse Forum (http://www.horseforum.com/forumindex.php)
- Meet the Community (/meet-community/)
- - dressage/trail rider from NV saying hello! (http://www.horseforum.com/meet-community/dressage-trail-rider-nv-saying-hello-78868/)
dressage/trail rider from NV saying hello!
hello all! i'm new to this forum and wanted to do as suggested and post a hello thread.
i live in the high desert of nevada with my 15yr old OTTB and my brand new (to me haha) 9mth old appaloosa colt.
i'm glad to be here and hope to meet some fun new people and learn what i can from all of you. :)
Hi There and welcome!
thanks! i'm glad to be here. seems like a nice group of people thus far. :)
Hello from Montana, and Welcome to the Forum! :D
Love to see some pics of your horses...
here we go!
this is jager (captain hook). he is a 17hh black 15 yr old OTTB that i got 5 years ago. he's my super attitude wonderful boy who still thinks he's a stud. ;)
and this is koda (still waiting on his registration papers so we'll see if i got the name i wanted). he's a 9mth old appy colt that i brought home last weekend. :D
Oh wow, Jager is really handsome, and that little Koda is going to be quite the looker too!
Thanks for posting pics!
Hello and welcome! I love Reno!
thanks! i'm partial to them both but i'm biased. ;)
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Add FuelBelt's Plus One bottle to have the extra water you need. It easily attaches via a belt loop to any FuelBelt hydration belt. A 7oz. bottle is included.
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text:
Padron Serie 1926 #1 box of 10 cigars are the perfect smoke for any time of day. Made to celebrate Jose O. Padron's 75th birthday, this cigar hits on every characteristic the master blender himself loves from a rich blend of longfiller tobaccos and a Nicaraguan Habano wrapper, all aged 5-10 years.
Best Maduro ever-Love them almost daily


text:
Taste the nouvelle Northwest in Braiden Rex-Johnson's latest cookbook, Pacific Northwest Wining & Dining. Recipes include Cervelle de Canut (Herbed Goat Cheese with Walnut Crostini); Baked Oysters with Orange-Thyme Beurre Blanc and Citrus Zest; and Blue Cheesecake.
Serves 6 to 8 as an appetizer
Makes 2 cups
Varietal: Chardonnay (unoaked)
or Syrah
With a whisk or in a food processor, whip the fromage blanc and crème fraîche with the shallots, lemon juice and zest, olive oil, parsley, and chives. Season to taste with salt and pepper.
To serve, spread the herbed goat cheese on the toasted walnut bread and arrange on a serving plate. Top with frisée leaves.
Buy Pacific Northwest Wining & Dining
This page created November 2007
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by Yiming Gong
1. NetFlow review
In the first part of this article series, we looked at what NetFlow is and how it can be used in the early detection of worms, spammers, and other abnormal network activity for large enterprise networks and Internet service providers. The article discussed some of the most common methods of flow-based analysis: Top N, Baseline and Pattern Matching techniques.
In this second and final part of the article, we'll look at three additional methods of analyzing the flow, including how to filter our flow results via TCP flags, in order to get a more granular view of network abnormalities. We'll discuss some ICMP issues, and then look at some of the various tools that exist to help implement and analyze our NetFlow solution. Let's get started.
2. TCP flags for NetFlow
One difficult task when performing flow-based analysis is that the administrator must evaluate a very large number of flow records. If he is just relying on the Top N, baseline and pattern matching methods, the administrator will merely get a coarse view of network abnormities. We've seen many times there are moderately intensive worms and other abnormal activities which appear intangible amongst the immense amount of legitimate traffic that is typically found in a large enterprise network. Those malicious hosts will not show up in the Top N lists, nor will we know in advance what key fields and values to 'grep' -- yet these are still malicious hosts that must be addressed.
In order to identify the abnormities more effectively and accurately, a better way to narrow the analyzable flow records is required. Fortunately, for most types of TCP-based worms and other abnormities, there is another useful field in flow records: analysis based on the TCP flags.
Worms, by their replicating nature, are programmed to seek as many victims as possible. Typically they send out hundreds or even thousands of probes to large blocks of IP addresses in a very short period of time. If a worm was designed to spread via TCP (as most of them are), during its propagation there will be a lot of corresponding TCP SYN packets sent out as it seeks vulnerable services in other hosts.
2.1 A typical worm's SYN scan process
In the patch a worm takes as it makes its way outside the corporate network, there are three possibile results to its SYN scan:
- The first possibility is that the destination host is alive, and the corresponding vulnerable service that was targeted is running.
As we all know, the three-way handshake that starts a normal TCP connection involves:
- First a client will send a SYN packet to the destination host.
- The destination host sends back a SYN/ACK packet.
- The client acknowledges the destination host's acknowledgment.
- A connection is established.
Figure 1, below, illustrates this handshake.
Figure 1: destination host is living and the TCP port is open
When a SYN packet arrives at the destination port of a host, if the port is open the SYN request sent from the worm will be responded to -- regardless of whether or not the service running on that port is vulnerable. Therefore, the standard TCP three-way handshake will be completed and subsequent packets carrying other TCP flags such as PUSH and ACK will be followed. In the first part of this article we mentioned that a V5 NetFlow record contains the cumulative OR of TCP flags in the 'entire' connection session. Therefore, using our the NetFlow approach we should expect to see a combination of TCP flags such as ACK/PUSH/SYN/FIN or ACK/SYN/FIN in flow record, flowing in both directions.
- The second possible result from the worm's SYN scan is that the destination host it attempts to connect to is not living, as shown below in Figure 2.
Figure 2: connect to a 'dead' destination host
Because the destination host is not alive, the SYN requests sent out by the worm will receive no response. From our NetFlow perspective, we will get a flow record in which only the SYN bit was set from worm host and sent to destination host.
- The third possible result is that the destination is alive but connection attempts from the worm are not functional, as shown in Figure 3.
Figure 3: destination host with closed TCP port
This simply means the destination host is indeed living but the port which the worm is trying to connect is closed. As we know, to establish a TCP connection a server must listen on that particular port. If a client connects to a server's non-listening port, the server will send back a RST/ACK packet. According to normal TCP implementation guidelines, the host will immediately stop any TCP connection attempts once it receives a RST. From the NetFlow angle, the TCP flag combination in the flow records will show only SYN requests from the worm host to the destination host.
Thus far I have discussed three possibilities when a worm's host SYN scans the network. There is one important fact about the worm to remember: when it tries to propagate, the destination addresses are typically generated at random, and normally there will be a large number of destination hosts that are not living or functional. Therefore in the outgoing traffic we should expect to see a large number of SYN bits set in the flow records associated with the worm-infected host. This characteristic is very useful and may be used as a key point for our flow-based detection of worms and other TCP based abnormalities. In section 2.2, below, we will discuss this detection process.
2.2 Three steps to process a flow file for TCP flags
When doing flow-based analysis, a captured flow file can be processed by the following steps:
- The first step is to search through the flow file, filter out all flow records that have only the SYN bit set, extract the source IP addresses of every flow record, count the occurrence of every unique IP, and then finally sort the records by the number of counts for each one. Following this process, we will end up with a suitable list of potentials. The administrator can set a threshold depending on the network size and traffic volume, whereby hosts whose counters are above the threshold should be considered as potentially malicious, and those under the threshold should be considered as benign.
- The second step is to search through the flow file again to extract all flow records where the source IP addresses are the ones found in the "potential malicious" list as generated in step 1 above. By taking a second look at the flow file in this way, we will get a detailed connection table for every potential host. The results of this search will be used for our third and final step in this process, and will help us to further identify the behavior of our suspicious hosts.
- The third step will give us some very meaningful data about the worm-infected hosts on our network. First read the output taken from step 2, and then for each host count the number of appearances of every unique destination port. Sort by the number of occurrences, and we will then get an IP address and its corresponding active ports table. The following is an example output generated by a little shell script that performs this task, as written by the author.
potential host1: 220.127.116.11 ------ 84 times probe on dstport 1025 76 times probe on dstport 80 72 times probe on dstport 2745 64 times probe on dstport 3127 48 times probe on dstport 6129
For a malicious host that is always trying to connect to one or several special ports, we can discover it in our reports by checking the corresponding services registered for the most active host's destination port in the matrix. In other words, using the above example, host 220.127.116.11 was infected with W32.gaobot.sa worm because it is scanning for the MyDoom backdoor on port 3127, the Bagle backdoor on port 2745, and the Dameware port on 6129. These are clearly the characteristics of worm W32.gaobot.sa.
In our goal is to evaluate the propagation of a worm from outside our network into the inside, flow records coming from outside that have the TCP flags RST/ACK set should be looked at. We know that a closed port will send back a RST/ACK to a TCP request, as was shown in Figure 3. If a worm is scanning a large block of living hosts for a certain vulnerability, those hosts with closed ports would send back a RST/ACK. For ingress traffic, if a destination (not source!) host in the flow records receives too many RST/ACK responses, the administrator should check out this destination IP seriously, as it is very likely infected with a worm.
3. ICMP issues
One of the purposes of ICMP is to provide feedback about problems in the communication environment of a network. Sometimes a ICMP type/code in the flow records could also be used to help us locate the potential malicious hosts.
The first thing to note is that there is no flow field that is directly named as an ICMP type or ICMP code, as was inferred in part 1 of this article series. Some people have suggested, then, that the type and code of ICMP requests cannot be identified in the captured flow data because that information is not specifically recorded. Does that mean we cannot use ICMP type/code for flow-based analysis? No. In actual fact, we can: ICMP type and code are indeed recorded in the NetFlow data, they are simply stored in the destination port field in the flow record.
For flow-tools, when one needs to obtain the ICMP type and code number, we just need to check the destination port field (dstPort). If the number appears in hex, we should convert it to decimal, and vice versa.
The following is example output of flow-tools in which the dstPort is in decimal.
srcIP dstIP prot srcPort dstPort octets packets 18.104.22.168 188.8.131.52 1 0 2048 28 1 22.214.171.124 18.104.22.168 1 0 2048 28 1 184.108.40.206 126.96.36.199 1 0 769 112 2 184.108.40.206 188.8.131.52 1 0 769 56 1
We can see that protocol field (prot) is 1, which means ICMP. The destination port is 2048, which is 800 in hex. Here 8 means ICMP type 8, and 00 is the code field for ICMP type 8, which means no code. So we can conclude that 800 is an ICMP echo request. In the same way, 769 is 301 in hex, which is ICMP type 3 and code 01, which means ICMP host unreachable.
There are two interesting types of ICMP packets that can be used for flow-based abnormal detection when analyzing a network's ingress traffic. It is also possible to use pattern matching methods to do ICMP flow analysis, as we will demonstrate.
3.1 ICMP destination unreachable
According to ICMP implement guidelines, if the destination network or the destination host is unreachable, the gateway MAY send destination unreachable messages to the source host, as shown below in Figure 4.
Figure 4: destination unreachable
3.2 ICMP port unreachable
For UDP requests, hosts with closed ports may send back ICMP port unreachable messages to the source host. If a worm spreads with UDP, it may then trigger many ICMP port unreachable flow records in the packets returned. This is shown below in Figure 5.
Figure 5: destination host with closed UDP port
If a host has an abnormal volume of ICMP port/host/network unreachable set of flow records, that may indicate that the host is acting abnormal.
3.3 Pattern matching methods
Another ICMP-based flow analysis method is pattern matching. Some worms and network attacks are carried out using ICMP, as we saw with the W32.Nachi.worm. When a host is infected with the worm, it will send out ICMP echo requests to the outside with a fixed length of 92 bytes. So we simply need to filter out the flow records with ICMP type 8 that have a 92-byte packet length, and hosts infected with this worm will be caught.
4. Special zones in the Enterprise
In enterprise networks there are always some servers that are protected with firewalls. Normally these servers should be hardened and have only fixed ports open to outside. Except for those fixed ports, any connection established between the server and outside should be prohibited.
We could use this characteristic to monitor the security of the servers using NetFlow.
4.1 ingress traffic
If we find any flow record whereby the destination IP contains a server IP, but the destination port is not in the server's functional port list and additionally the TCP flags in the flow record contains ACK (but not RST/ACK), an alert should be triggered.
The above suggestions perhaps indicates two points. First, it tells us that the firewall in front of the host has something wrong with it, as it has let a connection (which should be prohibited) get established. An exception to this would be that the connection launched by outside incorrectly contains only a ACK packet; regardless, this kind of connection should not have appeared. Secondly, the appearance of this flow record also indicates the server may have an abnormal port open to outside!
4.2 egress traffic
When we see any flow record whereby the source IP contains a server IP but the source port is not on the server's list of functioning ports, and additionally the TCP flags in the flow record are not RST/ACK, an alert should be triggered.
As well, if we spot any data being transferred at the same time as the above, a red alert should be immediately raised! It is quite possible that the server has been broken into. Perhaps a backdoor has been actived, and maybe a new service has been enabled.
5. Implementation guidelines
Thus far we have discussed several methods that can be used for flow-based detection of worms and other network abnormal activities, however no detailed implement instructions have been provided. In reality, if you follow the main points of these methods as discussed in this article series, implement will actually be fairly easy.
For instructions on how to enable NetFlow on a specific router, readers can check the corresponding manufacture's website. Some example NetFlow configurations for popular Cisco and Juniper routers can be found at: http://www.splintered.net/sw/flow-tools/docs/flow-tools-examples.html
Although there are both commercial and open source solutions for flow file analysis, the author himself prefers the open source solution. Commercial products normally have built-in and fixed functions which are always difficult to extend. Most importantly, commercial flow analysis tools don't have the flexibility as existing open source options.
For open source solutions we have many choices, such as cflowd, SiLK, and flow-tools. All of these work quite well and on many different UNIX platforms.
SiLK is a collection of NetFlow tools developed by CERT/AC to facilitate security analysis in large networks. It consists of a packing system and an analysis suite. SiLK provides administrators with great flexibility in its ability to process the flow data, but in my option, SiLK still needs some revisions and enhancements to make it run more smoothly. SiLK can be found at http://silktools.sourceforge.net.
Flow-tools is a powerful and helpful program for NetFlow related work. There are some available add-ons, and overall it provides greater flexibility and controls than many of the other tools. Flow-tools can be found at http://www.splintered.net/sw/flow-tools/.
- cflowd
cflowd is the classic traffic flow analysis tool. It can be found at , however note that it is no longer supported by CAIDA anymore, so consider one of the other tools below.
In addition to these, there are some other programs such as FlowScan and CUFlow which can be used for flow-based analysis work. All of these can be considered to be valuable tools.
6. Summary
This article series has discussed the flow-based detection of worms and abnormal activities. Part one talked about the basic concept of NetFlow, and then the first two of the five flow-based analysis methods were put forward. The second part of the article discussed the final three analysis methods. In summary, these five methods of analysis are Top N and Baseline, Pattern Matching, TCP flags, ICMP issues and special zone for large enterprises. With these methods, network administrators can detect network-wide abnormities much more effectively.
There is no silver bullet for security detection on large network infrastructure, but with NetFlow we may attain further insight into the traffic crossing our entire network -- and make it run better.
Yiming Gong has worked for China Telecom for more than 5 years as a senior system administrator, and now he works as a Technical Manager in China Telecom System Integration Co.Ltd. He also has a personal homepage focusing on network/system security.
Comments on this article can be sent to the editor.
This article originally appeared on SecurityFocus.com -- reproduction in whole or in part is not allowed without expressed written consent.


text:
At 12:59 PM 11/25/99 -0600, you wrote:
> Why am I most thankful?
What a great idea, Kate!
I am thankful that my husband and I are in good health and here to
celebrate another Thanksgiving.
I am thankful for the rain we so desperately needed.
I am thankful, like you, to have a place on the internet where I am free to
be right, or wrong, or stupid, or profound, and no one will tell me to leave.
I am thankful for the friends I have made on hosta-open, the purveyors of
incredible hostas that I have met here, and for two members in particular
that have brightened my life in so many ways and talked me into joining the
list (You know who you are!).
I will be thankful in two hours if I manage not to burn down the house
smoking a duck for dinner.
My best Wishes for all of you.
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