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Aging is associated with a loss of body weight, often referred to as the anorexia of aging, which is accompanied by loss of muscle mass (sarcopenia) and bone loss (osteoporosis). The cytokine-like hormone leptin is secreted from peripheral fissues including fat and skeletal muscle, and leptin deficiency is associated with decreased bone mass as well as loss of muscle mass and strength. We have identified an animal model, the aged C57BL/6 mouse, that shares a number of key features in common with the aging human musculoskeletal system: an age-related decline in serum lepfin, decline in serum IGF-1, decreased muscle mass, and loss of bone density. We have also found that leptin treatment increases serum IGF-1 and muscle mass in aged mice. Our preliminary studies therefore suggest that the decline in musculoskeletal funcfion that occurs with aging is due in part to alterations in the lepfin-IGFI axis. We also show for the first time that musculoskeletal tissues from aged mice show increased expression of microRNAs (miRNAs) targefing leptin. The central hypothesis of our proposal is that leptin is a key factor linking nutrient intake with normal musculoskeletal funcfion, but leptin signaling in musculoskeletal tissues is altered with age, contributing direcfiy to age-related loss of muscle and bone.
Specific Aim 1 will identify cell- and tissue-specific alterations in leptin expression with age, and will define the role of circulating leptin in regulating age-associated changes in the local and systemic secretion of IGF-1.
Aim 2 will determine how aging and nutrient intake alter leptin sensitivity and the expression of functional leptin receptors in muscle and bone cells.
Aim 3 will identify fissue-specific microRNAs that are altered with age and leptin treatment, and functional in vitro studies will be used to define the role of these small molecules in the proliferation and differentiation of myogenic and osteogenic cells. The proposed studies will therefore define new therapeutic targets and diagnostic biomarkers related to sarcopenia and fall risk that can be developed to improve upon exisfing fracture treatment and prevention strategies.
The research proposed in this application will investigate the basic mechanisms by which aging alters normal leptin signaling in muscle and bone, and as such will contribute directly to the development of new therapeutic strategies and diagnostic biomarkers related to fall risk and debilitating bone fractures.
|El Refaey, Mona; Zhong, Qing; Hill, William D et al. (2014) Aromatic amino acid activation of signaling pathways in bone marrow mesenchymal stem cells depends on oxygen tension. PLoS One 9:e91108
|Herberg, Samuel; Kondrikova, Galina; Periyasamy-Thandavan, Sudharsan et al. (2014) Inkjet-based biopatterning of SDF-1? augments BMP-2-induced repair of critical size calvarial bone defects in mice. Bone 67:95-103
|Pan, Guodong; Cao, Jay; Yang, Nianlan et al. (2014) Role of glucocorticoid-induced leucine zipper (GILZ) in bone acquisition. J Biol Chem 289:19373-82
|Refaey, Mona El; Zhong, Qing; Ding, Ke-Hong et al. (2014) Impact of dietary aromatic amino acids on osteoclastic activity. Calcif Tissue Int 95:174-82
|Herberg, Samuel; Shi, Xingming; Johnson, Maribeth H et al. (2013) Stromal cell-derived factor-1? mediates cell survival through enhancing autophagy in bone marrow-derived mesenchymal stem cells. PLoS One 8:e58207
|Arounleut, Phonepasong; Bialek, Peter; Liang, Li-Fang et al. (2013) A myostatin inhibitor (propeptide-Fc) increases muscle mass and muscle fiber size in aged mice but does not increase bone density or bone strength. Exp Gerontol 48:898-904
|Bollag, Wendy B; Isales, Carlos M (2013) GRowing an epidermal tumor. J Invest Dermatol 133:2659-62
|Fulzele, Sadanand; Chothe, Paresh; Sangani, Rajnikumar et al. (2013) Sodium-dependent vitamin C transporter SVCT2: expression and function in bone marrow stromal cells and in osteogenesis. Stem Cell Res 10:36-47
|Herberg, Samuel; Fulzele, Sadanand; Yang, Nianlan et al. (2013) Stromal cell-derived factor-1* potentiates bone morphogenetic protein-2-stimulated osteoinduction of genetically engineered bone marrow-derived mesenchymal stem cells in vitro. Tissue Eng Part A 19:1-13
|Bowser, Matthew; Herberg, Samuel; Arounleut, Phonepasong et al. (2013) Effects of the activin A-myostatin-follistatin system on aging bone and muscle progenitor cells. Exp Gerontol 48:290-7
Showing the most recent 10 out of 13 publications


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Winous Point Marsh Conservancy's mission is to protect, restore, enhance, and wisely manage coastal wetlands and watersheds in southwest Lake Erie. Through a combination of private contributions and leveraged grant funds, the Winous Point Marsh Conservancy is working to aid and facilitate wetland conservation programs and research in cooperation with neighbors, state and federal agencies, and other non-profit conservation groups.
Posted in Uncategorized Comments Off on WINOUS POINT

subset: commoncrawl


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Copper Rises Before Fed Minutes as Global Inventories DeclineBloomberg News
Copper advanced for a third day amid declining global inventories and before the release of U.S. Federal Reserve meeting minutes later today.
The contract for delivery in three months on the London Metal Exchange climbed as much as 0.3 percent to $7,370 a metric ton and traded at $7,359.25 at 4:13 p.m. in Shanghai. The industrial metal, used in wiring and electronics, touched $7,460 on Jan. 2, the highest level since June 5.
Inventories tracked by exchanges in London, New York and Shanghai are at the lowest since November 2012, with LME stockpiles falling for a 44th session. The Fed minutes to be released today document the December meeting in which policy makers decided to start tapering the bond buying program that has supported global assets.
"Coppered rose with the low inventories," said Lian Zheng, an analyst at Xinhu Futures in Shanghai.
Metal for delivery in March closed 0.4 percent higher at 52,060 yuan ($8,603) a ton on the Shanghai Futures Exchange. Copper for delivery in March climbed 0.3 percent to $3.3685 a pound on the Comex in New York.
On the LME, nickel, lead, zinc and tin also rose. Aluminum was little changed.
— With assistance by Alfred Cang


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A pair of flip flops from Animal that are great for the pool or beach. One pair has stylish stripes with the Animal logo emblazoned across them and the other boasts a pretty butterfly.
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Lacking a toilet roll holder? Here are some creative, low-tech solutions to solve the loo paper placement conundrum.
Above: Toilet paper suspended from a loop of rope, slung over a ladder.
Above: A vintage soap dish holder works well as a toilet roll holder; image via Lonny.
Above: Spotted in the bathroom at Dosa 818 in Los Angeles, toilet paper in a clay bowl filled with small pebbles.
Above: Two approaches to low-tech toilet paper storage.


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spast/past continuous exercises
spast/past progressive
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Material Type: Reference Material
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Date Added to MERLOT: January 11, 2013
Date Modified in MERLOT: January 11, 2013
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Keywords: spast/past progressive
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Spectro Q6000 Fuel Dilution Meter
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Patrick Nichols serves as Corel's CEO and joined the company in 2009. Before becoming Chief Executive Officer, Patrick held the role of President of WinZip and General Manager of Corel, Roxio, Pinnacle and ReviverSoft, leading the transformation of Corel's acquired brands and setting the strategic direction of the company's product lines. Patrick has played a key role in Corel's success, serving on the management team responsible for nearly tripling the company's operating income over the last three years.
Prior to joining Corel, Patrick served as a General Manager within the Trilogy/Versata family of companies where he was responsible for new acquisitions and business ownership of a portfolio of Versata companies. Before joining Trilogy/Versata, Patrick worked as a product manager and technical consultant at Microsoft, and served as a researcher for the Department of Defense and Department of Energy through the Cornell Engineering and Theory Center. He holds a BS from Cornell University.
Chris DeBiase is Corel's Chief Financial Officer and has become an invaluable part of the executive team as he leads the company's Finance, M&A and Human Resources departments.
Chris has a BA in Economics from Brown University, and prior to joining Corel in March of 2010, served as the Vice President of Business Development for Ingres Corporation, where he was instrumental in managing a variety of M&A, Business Development and Finance functions. Chris also spent a number of years in the financial trenches of Wall Street where he served as Vice President Equity Research at both Goldman Sachs and Citigroup.
Grace Pura is Corel's General Counsel and has been an integral member of the Corel management team for the past two years. Leading the company's legal function globally, Grace has been instrumental in the successful completion of Corel's M&A transactions.
Prior to joining Corel, Grace served as Associate General Counsel for Joyent, Inc. Previously, she served as corporate counsel to Ingres, Fortinet and Silicon Valley Bank on a variety of matters, including mergers and acquisitions, strategic contract negotiations, litigation management and employment disputes. Grace also provided business development and fund raising support to Zero2IPO, a China-based company focusing on providing financial services to start-up companies in China. She started out her legal career as litigation associate with Ropers, Majeski, Kohn & Bentley. Grace achieved her law degree at the University of the Pacific – McGeorge School of Law.
Jussi Arovaara has served as a member of Corel's senior executive team since 2011. In his earlier career with Corel, Jussi gained experience in a wide variety of roles, including senior management positions within Sales, Operations and Marketing, including Regional Manager for Nordic Region, Director of Business Development and Vice President of EMEA Sales. In his current role as Corel's Vice President of Global Sales, Jussi is responsible for defining global sales strategies, and driving the company's global channel and OEM sales across business units. He also oversees Corel's Field Marketing and Operations in Corel's global regions.
Prior to joining Corel, Jussi worked in IT distribution as a business unit leader covering the Nordic Region, Baltic Region and Russia. A Finnish native with over 20 years' experience in the technology sector, Jussi brings a wealth of international experience to his role having lived and worked in Finland, Canada and the UK. Jussi is also a member of the board of F-Secure Corporation and its audit committee. He is also a member of the Institute of Directors and during his time at Corel has served as a member of Business Software Alliance, EMEA Committee. On the rare occasions when Jussi isn't working, he can often be found sailing or skiing, with his trusty GoPro camera always close at hand.
Monika Leissle serves as VP of Human Resources for Corel. In this role, she is responsible for Corel's global HR operations working with employees in North America, Asia and Europe. Monika joined Corel in 2010 and previously held the positions of HR Director for EMEA & APAC and HR Manager, EMEA.
Prior to joining Corel, Monika served as Head of Human Resources at Aston Carter in the UK. She graduated from the University of West London.
Prasannaa Ganesan is VP of Operations, responsible for business operations at Corel including customer support and manufacturing. Prasannaa joined the company as Director of Operations for WinZip in 2010. Respected for his strong sense of fiscal responsibility, he played a key role in dramatically increasing profitability within the WinZip business and subsequently for Corel's Roxio, Pinnacle and Digital Media product groups.
Prior to joining Corel, Prasannaa served as Program and Delivery Director at Versata and Trilogy. Prasannaa pursued his Masters of Science in Electrical engineering from North Carolina Agricultural & Technical State University following a Bachelor of Engineering from Shanmugha Arts, Science, Technology and Research Academy. An engineer at heart, Prasannaa has a passion for automation and gadgets.
Rob Charlebois is Corel's VP of Global eCommerce, responsible for the company's global online sales and marketing strategies across all its product lines, including Corel, WinZip, Roxio, Pinnacle and ReviverSoft. During his 10 year tenure, Rob's impressive track record includes building Corel's direct ecommerce model which now accounts for more than 40% of the company's total revenue. Rob has served as Sr. Director of eCommerce for WinZip as well as Director of eCommerce for Corel.
Prior to joining Corel, Rob has held various strategic marketing positions at companies including Buystream, N-able Technologies and Nexinnovations. He holds a Bachelor of Political Science from the University of Ottawa and a Diploma in Architecture from Algonquin College.


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The Sailing Leadership Forum 2016 schedule features presentations from experts on a wide variety of topics that address the challenges we all share.
While many of these presentations focus on new topics, many expand on the presentations delivered at the 2014 Sailing Leadership Forum.
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Sailing Leadership Forum 2016 FINAL Schedule (Last Published 1-27-16)


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2013 Porsche Cayman S Thrashed - /CHRIS HARRIS ON CARS
Chris Harris reviews the new 2013 Porsche Cayman S in Portugal.
Sold the Porsche, Bought a Ferrari 599 - /CHRIS HARRIS ON CARS
The finance payments were too much, someone offered me good money for it, so I sold the Porsche. 599 values have hit the skids in the UK, Ferrari won't let me drive its cars any more, and I miss driving them so I bought, a 599. It's fast.
415hp Wagon S4 vs 275hp Cayman, With Chris Harris - /TUNED
Matt showed up in t he UK to bother Chris, and over pints, got into a discussion about the "ideal" amount of tuning for a daily driver, as well as whether we'd rather have a fast sleeper Audi or a slow 2013 Porsche Cayman. Agree with us?
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Check Out James Deen's New Movie
Relax, it's not porn.
James Deen, Jewish porn star, makes his non-X-rated debut in "The Canyons," the upcoming movie co-starring Lindsday Lohan and based off a script by Bret Easton Ellis.
The film — which was rejected by SXSW for having "an ugliness and a deadness to it," marks a long-awaited (for her, at least) comeback for Lindsay Lohan, whose onset antics were extensively documented in Stephen Rodrick's article in the New York Times, "Here Is What Happens When You Cast Lindsay Lohan in Your Movie."
In his article, Rodrick added that to his surprise, James Deen was possibly the best thing to come out of this film.
"[The house] quickly became the most dependable player in the film after James Deen," he described. "On the first day of shooting in Malibu, Deen aw-shucked his way around the predominantly male crew. He wasn't a big man; maybe 5-8 and 150 pounds, but they regarded him with wonder."
Despite being a nightmare to work with, Lohan's acting abilities appear to be back on track, though it remains to be seen which side of her will win out in the end.
"I think Lohan has more natural acting talent than Monroe did, but, like Monroe, her weakness is her inability to fake it," director Paul Schrader wrote in Film Comment.
Judging by the trailer, good or bad, it will definitely not be boring.
See for yourself below:
Your Comments
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Musings in 140 or less…
- I Ignored Trump News for a Week. Here's What I Learned. nyti.ms/2ludepa 9 hours ago
- RT @Cubs: 😍 https://t.co/EUtl12Nhw3 17 hours ago
- But not very many other people do. twitter.com/azcentral/stat… 1 day ago
- Hooray! The best anchor in the valley is back tonight for a perfect end to end President's Day!! @KrisPickelNews… twitter.com/i/web/status/8… 1 day ago
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Tag Archives: purple ride
Battling the horror of pancreatic cancer with my feet…
Fighting the horrors of pancreatic cancer with my legs…
I just surpassed the halfway mark toward my goal with a little over one week left. Thanks to all who have pledged their support for my scenic loop challenge bike ride! Please join these wonderful people with your support in the battle against a terrible disease and support for those who suffer from the horrors of pancreatic cancer. Thank you!
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There's extra funding of up to £10,000 (or 25% of funding target) available to artists and arts organisations raising between £4,000 and £40,000 on Crowdfunder.
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AXA is providing £15,000 of match funding for road safety initiatives via Crowdfunder to enable local projects find the funding necessary to make UK roads safer.


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Academic writing, all subjects, undergrad level - SAMPLES
- Status Closed
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Project Description
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Splashtop 2 Remote Desktop App for Android
'Splashtop is the easiest and fastest remote desktop app for accessing your Windows or Mac computer using your Android phone or tablet, from anywhere and at anytime!Use Splashtop for free to access your computer on the local network with best-in-class video streaming performance. Get full access to ALL of your applications, documents, emails, full browser with Flash and Java support, and games. Also get full access to your entire media library and documents. And more!To access your computer from... More
Material Type: Development Tool
Technical Format: HTML/Text
Date Added to MERLOT: December 10, 2013
Date Modified in MERLOT: January 21, 2014
Submitter: Cathy Swift
Reviewed by members of Editorial board for inclusion in MERLOT.Editor Review (not reviewed)
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Welcome to the website of Dr. Jack P. Newell, Jr., DDS.
We accept three types of adult Medicaid:
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New patients are welcome! For 35 years, our office has been specializing in family dentistry and accepting children as young as 1 year old.
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Jack P. Newell DDS
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Phone Number: 985-652-2425 • Fax Number: 985-651-7817
Phone Number: 985-652-2425 • Fax Number: 985-651-7817


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Phoenix Suns
Second-generation players work out for the Phoenix Suns
PHOENIX — If what people say is true and the apple doesn't fall far from the tree, then sophomore small forwards Jerami Grant of Syracuse and Glenn Robinson III of Michigan may already be a step ahead of their fellow draft hopefuls.
Basketball is in their blood, literally.
Grant is the son of Harvey Grant, an 11-year NBA veteran. His uncle is Horace Grant, who spent 17 seasons in the league. Both father and uncle were first-round selections.
Robinson's father, Glenn "Big Dog" Robinson, was the No. 1 overall pick in 1994 as college basketball's consensus Player of the Year and went on to play 11 years in the NBA.
"Enjoy every moment of it. You don't get it back," said Robinson of the advice his father gave him ahead of the pre-draft process.
At 6-foot-7 and 220 pounds, Robinson has the prototypical size and athleticism for an NBA wing player.
"He shoots it with ease," head coach Jeff Hornacek said after Tuesday's workout.
Robinson, however, saw many of his numbers drop from his freshman to sophomore season. He went from shooting 57.2 to 48.8 percent from the field and 32.4 to 30.6 percent from three-point range.
"I think Robinson is a better shooter than his numbers indicate," GM Ryan McDonough said. "His stroke looks good."
Robinson, too, believes his shooting will only get better.
"I've been shooting the ball pretty well and that's just my job to continue to shoot with confidence," he said. "I have no doubt in my mind that (teams) will see that."
Hitting the outside shot is where Grant, 6-foot-8 and 214 pounds, needs to improve the most. He was a post player at Syracuse and therefore did not get many spot-up opportunities.
"Definitely needs to get better," he said of his stroke from the outside. "It's improving. It's been improving so far since I've been in college and it improved after the season. It definitely needs to get a lot better in order to play in the NBA, but I definitely think it's getting there."
Grant attempted only 20 threes, making six in his two-year career. He led his team in rebounding (6.8), ranked third in scoring (12.1) and second in steals (1.9).
"His length and athleticism are pretty freakish," said McDonough, who mentioned Grant displayed some impressive finishes at the basket during the workout.
"The transition from the power forward to the small forward is a difficult one," McDonough continued. "Sometimes it can take a few years. Marcus Morris is one of the few guys who have done it successfully, but he has the physical tools -— like I said the length, athleticism and bounce -— to potentially make that work."
NBA bloodlines, however, will only carry Grant and Robinson so far.
"We try to evaluate each guy on his own merits," McDonough said. "I think one of the advantages is probably more off the court and dealing with (the media). They've been kind of in the spotlight their whole life. I think they're more accustomed to this. This is kind of what they've been doing their whole life. I think that helps them, but on the court it really doesn't matter. When the ball goes up all that kind of peripheral stuff goes away."
Grant and Robinson were two of the six players the Suns worked out, joining New Mexico power forward Cameron Bairstow, Memphis point guard Joe Jackson, Connecticut point guard Shabazz Napier and St. Joseph small forward Ronald Roberts, Jr.
Napier is one of the few seniors in this 2014 draft class who could hear his name called in the first round on June 26.
"The four years gave me the most experience that I can actually say that no one else has in this draft. I was there through the good times and the rough times," he said of winning two national championships and a one-year postseason ban as a result of the program's low Academic Progress Rate scores. "I've seen a lot. I dealt with a lot. As a point guard, you're the general on the court. You can emphasize whether you win games or lose games so you experience a lot. That's the biggest thing, I think, I have."
Added McDonough, "We place a value on winning. Of the guys in the draft, he's probably one of the most ready to come in and make an impact right away."
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Tuesday February 21
Kevin Pelton discusses the DeMarcus Cousins deal, the NBA Trade Deadline and which teams could be ma
Tuesday February 21
See who won the "Hope it was Tito's" award, the "Wish I'd thought of that" award + more.
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Earl Watson explains the importance of organizational culture before making trades.


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Jin Jiang MingCheng Hotel
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JinJiang MingCheng Hotel is commissioned by the Jiangsu bright Investments Limited investment in Shanghai Jin Jiang International Hotel Management Co.Ltd. under the management of a quasi five star luxury business hotel. the hotel is located in Yancheng City.Jiangsu Province poly LONGHU gathering next to Yancheng Chiefcenter. Will trial opened in May 2013. The main hotel building is 21 floors above ground. the 248 rooms has excellent urban landscape. all kinds of Chinese and Western restaurant seats up to 900. as well as of all sizes intelligent conference room. business center. fitness center.swimming pool.tennis courts.chess room services.


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Krisztina Szremkó
From Wikipedia, the free encyclopedia
(Redirected from Krisztina Szremko)
The native form of this personal name is Szremkó Krisztina. This article uses Western name order when mentioning individuals.
|Personal information
|6 January 1972
Medal record
Krisztina Szremkó (born 6 January 1972 in Dunaújváros) is a female water polo player from Hungary, who competed for her native country at the 2004 Summer Olympics in Athens, Greece.
She played professional water polo for Dunaújváros, Eger, BVSC, Szentes, and Mediterrane. Szremkó's biggest success was winning the world title with the Hungary women's national team in 1994.
- (Hungarian) Profile
|This biographical article relating to a Hungarian water polo figure is a stub. You can help Wikipedia by expanding it.


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The Central Information Commission (CIC) has imposed a monetary penalty on an official of the Municipal Corporation of Delhi (MCD). The reason: He supplied misleading information and delayed in replying to an application by an RWA under the Right to Information (RTI) Act.
Fed up with years of dilly-dallying by the MCD, residents of Raja Garden used the RTI to find out about civic facilities in their area. But even the RTI failed to evoke a response from the civic body, when they approached the CIC.
The CIC in its decision in June pulled up the MCD's public information officer (PIO) for not providing information on time and to fix responsibility for the delay. In its decision on August 25, the CIC has imposed a penalty on him under section 20 (1) of the RTI Act for a delay of 32 days at the rate of Rs 250 per day, amounting to Rs 8,000.
The case pertained to an area occupied in allegedly in an unauthorised manner in Raja Garden. Almost two decades ago, a fire destroyed a timber mart in the area and the traders had been relocated. But many of them came back and continued to occupy the original place.
The RWA filed an RTI application in August 2008 and sought to know whether the MCD had acquired any land for civic facilities.
The CIC had in June asked the MCD to give the names of the officers responsible for the delay to the commission before June 30 and also asked to ensure that the applicant is provided with the relevant information before June 25.
When the MCD sent its reply, Commissioner Shailesh Gandhi on August 25, imposed this penalty on the PIO and asked the MCD to ensure that the amount is recovered from his salary by November 2009.


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Saturday, March 10, 2012
Preemptive President or Preemptive Opinion?
Gerard N. Magliocca
To follow on Mark and Jack's posts, I want to make two observations. The first is that there is a simple diagnostic that indicates whether a president is reconstructive or preemptive under Skowronek's theory. The party of the reconstructive president always wins a third term (Jefferson/Madison, Jackson/Van Buren, Lincoln/Grant, FDR/FDR, Reagan/Bush). Preemptive ones do not have the clout to pull this off, though in two instances they got close (Eisenhower/Nixon, Clinton/Gore). So if Obama is reelected and then followed by Joe Biden or Hillary, for example, he was a reconstructive president. Tune in 4 years from now.
As to AA, Kennedy in Parents Involved said he supports race conscious programs but has yet to vote to uphold one yet. Fisher doesn't really sound like one he would either. It would be helpful if he found one he liked.
Roberts opinion in NAMUNDO aside, I'm not aware of Kennedy showing much of a sign of wanting to overturn VRA. I realize Boerne taken to its logical conclusion would, but Kennedy manages to draw lines others find unprincipled.
I'd be curious to see a "preemptive opinion" by the Roberts Court. I too doubt the ACA would be one, though it taking up the state coercion argument that even the 11th Cir. rejected is interesting.
There is also the "Anticipatory Overrulings" idea.
This is an honest question: what are the limits on the political capital of a majority on the Supreme Court? That is, if you have an established pattern of working together, wouldn't such expenditures be minimal compared to those required within a less obviously factional group?
So if Obama is reelected and then followed by Joe Biden or Hillary, for example, he was a reconstructive president. Tune in 4 years from now.
Tune in in seven months.
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Books by Balkinization Bloggers
Sanford Levinson, Nullification and Secession in Modern Constitutional Thought (University Press of Kansas 2016)
Sanford Levinson, An Argument Open to All: Reading The Federalist in the 21st Century (Yale University Press 2015)
Stephen M. Griffin, Broken Trust: Dysfunctional Government and Constitutional Reform (University Press of Kansas, 2015)
Frank Pasquale, The Black Box Society: The Secret Algorithms That Control Money and Information (Harvard University Press, 2015)
Bruce Ackerman, We the People, Volume 3: The Civil Rights Revolution (Harvard University Press, 2014)
Balkinization Symposium on We the People, Volume 3: The Civil Rights Revolution
Joseph Fishkin, Bottlenecks: A New Theory of Equal Opportunity (Oxford University Press, 2014)
Mark A. Graber, A New Introduction to American Constitutionalism (Oxford University Press, 2013)
John Mikhail, Elements of Moral Cognition: Rawls' Linguistic Analogy and the Cognitive Science of Moral and Legal Judgment (Cambridge University Press, 2013)
Gerard N. Magliocca, American Founding Son: John Bingham and the Invention of the Fourteenth Amendment (New York University Press, 2013)
Stephen M. Griffin, Long Wars and the Constitution (Harvard University Press, 2013)
Andrew Koppelman, The Tough Luck Constitution and the Assault on Health Care Reform (Oxford University Press, 2013)
James E. Fleming and Linda C. McClain, Ordered Liberty: Rights, Responsibilities, and Virtues (Harvard University Press, 2013)
Balkinization Symposium on Ordered Liberty: Rights, Responsibilities, and Virtues
Andrew Koppelman, Defending American Religious Neutrality (Harvard University Press, 2013)
Brian Z. Tamanaha, Failing Law Schools (University of Chicago Press, 2012)
Sanford Levinson, Framed: America's 51 Constitutions and the Crisis of Governance (Oxford University Press, 2012)
Linda C. McClain and Joanna L. Grossman, Gender Equality: Dimensions of Women's Equal Citizenship (Cambridge University Press, 2012)
Mary Dudziak, War Time: An Idea, Its History, Its Consequences (Oxford University Press, 2012)
Jack M. Balkin, Living Originalism (Harvard University Press, 2011)
Jason Mazzone, Copyfraud and Other Abuses of Intellectual Property Law (Stanford University Press, 2011)
Richard W. Garnett and Andrew Koppelman, First Amendment Stories, (Foundation Press 2011)
Jack M. Balkin, Constitutional Redemption: Political Faith in an Unjust World (Harvard University Press, 2011)
Gerard Magliocca, The Tragedy of William Jennings Bryan: Constitutional Law and the Politics of Backlash (Yale University Press, 2011)
Bernard Harcourt, The Illusion of Free Markets: Punishment and the Myth of Natural Order (Harvard University Press, 2010)
Bruce Ackerman, The Decline and Fall of the American Republic (Harvard University Press, 2010)
Balkinization Symposium on The Decline and Fall of the American Republic
Ian Ayres. Carrots and Sticks: Unlock the Power of Incentives to Get Things Done (Bantam Books, 2010)
Mark Tushnet, Why the Constitution Matters (Yale University Press 2010)
Ian Ayres and Barry Nalebuff: Lifecycle Investing: A New, Safe, and Audacious Way to Improve the Performance of Your Retirement Portfolio (Basic Books, 2010)
Jack M. Balkin, The Laws of Change: I Ching and the Philosophy of Life (2d Edition, Sybil Creek Press 2009)
Brian Z. Tamanaha, Beyond the Formalist-Realist Divide: The Role of Politics in Judging (Princeton University Press 2009)
Andrew Koppelman and Tobias Barrington Wolff, A Right to Discriminate?: How the Case of Boy Scouts of America v. James Dale Warped the Law of Free Association (Yale University Press 2009)
Jack M. Balkin and Reva B. Siegel, The Constitution in 2020 (Oxford University Press 2009)
Heather K. Gerken, The Democracy Index: Why Our Election System Is Failing and How to Fix It (Princeton University Press 2009)
Mary Dudziak, Exporting American Dreams: Thurgood Marshall's African Journey (Oxford University Press 2008)
David Luban, Legal Ethics and Human Dignity (Cambridge Univ. Press 2007)
Ian Ayres, Super Crunchers: Why Thinking-By-Numbers is the New Way to be Smart (Bantam 2007)
Jack M. Balkin, James Grimmelmann, Eddan Katz, Nimrod Kozlovski, Shlomit Wagman and Tal Zarsky, eds., Cybercrime: Digital Cops in a Networked Environment (N.Y.U. Press 2007)
Jack M. Balkin and Beth Simone Noveck, The State of Play: Law, Games, and Virtual Worlds (N.Y.U. Press 2006)
Andrew Koppelman, Same Sex, Different States: When Same-Sex Marriages Cross State Lines (Yale University Press 2006)
Brian Tamanaha, Law as a Means to an End (Cambridge University Press 2006)
Sanford Levinson, Our Undemocratic Constitution (Oxford University Press 2006)
Mark Graber, Dred Scott and the Problem of Constitutional Evil (Cambridge University Press 2006)
Jack M. Balkin, ed., What Roe v. Wade Should Have Said (N.Y.U. Press 2005)
Sanford Levinson, ed., Torture: A Collection (Oxford University Press 2004)
Balkin.com homepage
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Bryan Colangelo Bio
President and General Manager
Bryan Colangelo, who enters his seventh season as the Suns president and 11th as general manager, was named The Sporting News NBA Executive of the Year after the Suns completed the third-greatest turnaround in NBA history while winning the Pacific Division Championship in 2004-05.
Colangelo, 40, built the Suns through a series of forward-thinking moves, beginning with the controversial trade of All-Star Stephon Marbury and Penny Hardaway to New York on January 5, 2004 creating the cap space necessary to sign eventual NBA MVP Steve Nash and Quentin Richardson, among others. Under the direction of the 2004-05 NBA Coach of the Year Mike D'Antoni, the new-look Suns finished a league-best 62-20 last season after posting a 29-53 record in 2003-04.
The 17-year Suns executive is part of the new ownership group that purchased the Suns on June 30, 2004 and he oversees all basketball operations of the NBA franchise. He is also part of the six-member management committee that governs the club, in addition to his duties as an alternate governor on the NBA's Board of Governors. Colangelo, who represents the Suns on the NBA's Competition Committee, previously held the positions of scout, assistant director of player personnel, and vice president/assistant general manager with the Suns, where he was directly involved in all aspects of player personnel, including evaluation, draft selection and transactions. He has also served as tournament director of the NIKE Desert Classic, an annual college All-Star basketball tournament held in Phoenix, from 1993 through 2001.
During Colangelo's tenure as general manager, the Suns have appeared in the NBA Playoffs eight of the last 10 seasons while posting an overall record of 439-349 (.557). Through various trades and free-agent moves, Colangelo has brought some of the league's best and most recognizable players to the Suns including All-NBA/All-Stars Tom Gugliotta, Hardaway, Jason Kidd, Marbury and Antonio McDyess. Colangelo and his staff have landed the team top-flight players like Shawn Marion, Amaré Stoudemire, Michael Finley and Nash via the draft.
In May 2005, Colangelo was named to the USA Basketball Men's Senior National Program Advisory Panel charged with selecting teams for the 2006 FIBA World Championship (Saitama, Japan), 2007 FIBA Americas Olympic Qualifying Tournament (TBA) and the 2008 Olympics (Beijing, China). This appointment follows a four-year commitment to the USA Basketball Men's Senior National Team Committee from 2001 through 2005, where he helped select teams for the 2001 Goodwill Games (Brisbane, Australia), the 2002 World Championship of Basketball (Indianapolis, Indiana), the 2003 FIBA Americas Olympic Qualifying Tournament (San Juan, Puerto Rico) and the 2004 Olympics (Athens, Greece).
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In addition to his responsibilities with the Suns, Colangelo served as president of Phoenix Arena Sports (PAS), the owning entity of the Arizona Rattlers (Arena Football League) and the operating entity of the Phoenix Mercury (WNBA) from June 1991 through June 2002. He managed the business administration, team operations and marketing sales of the Rattlers, Mercury and other exhibition events including tennis, hockey, indoor soccer, boxing and volleyball. Highlights of his involvement with PAS include the 1997 and 1994 (the state of Arizona's first) World Championship campaigns of the Rattlers, setting the league attendance mark with the Phoenix Mercury in the WNBA's inaugural season, overseeing the Mercury's run into the 1998 WNBA Finals and his selection as the AFL's 1993 Executive of the Year. The Rattlers also won the AFL Commissioner's Award as the top franchise on and off the field for an unprecedented five straight years from 1996 to 2000.
A 1983 graduate of Central High in Phoenix, Colangelo remains active in the community serving on the board of directors of the Arizona Zoological Society, Boys & Girls Clubs of Metropolitan Phoenix and Phoenix Suns Charities. He recently completed posts on the board of directors of the Arizona Sports Council (Grand Canyon State Games), Phoenix Chamber of Commerce and Phoenix Art Museum and he has served as co-chair of the annual Black Family and Child Services dinner. Appointed by former Phoenix Mayor Skip Rimsza in 1999, Colangelo recently completed a three-year term as an executive committee member and vice chairman of the Greater Phoenix Economic Council (GPEC).
A 1987 graduate of Cornell University with a bachelor of science degree in business management and applied economics, Colangelo and his wife Barbara are parents of a son, Mattia and a daughter, Sofia.


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Educators in Toronto, Ontario, credit two initiatives for an increased interest in reading among students at a time when other districts are closing school libraries. Students who participate in Just Read It and a writers-in-residence programme read books and submit reviews to a Just Read It website. Students who submit reviews are eligible to win prizes, such as free books or visits from one of three award-winning authors.
Full Story:The Toronto Star


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Crown Deli, deli, listed under "Delis" category, is located at 88 Atlantic Ave Brooklyn NY, 11201 and can be reached by 7183300594 phone number. Crown Deli has currently 0 reviews.This business profile is not yet claimed, and if you are the owner, claim your business profile for free. If you are not the owner you can invite this business to join by email or by phone.Browse all Delis in Brooklyn NY. Discover census data for Brooklyn, NY.
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Snap's e-commerce site may not be focused on sales
Snap launches Spectacles.com, an e-commerce site where shoppers can buy sunglasses with a built-in camera.
Snap's e-commerce site may not be focused on sales
Snap launches Spectacles.com, an e-commerce site where shoppers can buy sunglasses with a built-in camera.
US e-commerce sales grow 15.6% in 2016
The web comprised nearly 42% of the growth in the U.S. retail market last year. E-commerce represented 11.7% of total sales in 2016, but ...
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KeentoWean.com, a UK-based web site retailer of weaning products for babies, rose to the number five position in Google search results for "weaning products" within two weeks of launch. There are lessons for other merchants in the tactics employed.
A United Kingdom-based web site focused on weaning products for babies rose to the number five position in natural search results on Google for the term "weaning products" within two weeks of launch. While the term is not overly competitive, the site used some tactics that can help other merchants raise their rankings on search results pages.
Emma Hine, founder of KeentoWean.com, attributes the site's high position in Google search in the U.K. to the site's focus on a niche market and the fact that the term "weaning products" is featured prominently on its home page. It also appears on every page on the site and in the site's subtitle.
Other sites may offer weaning products, but they typically are part of a larger inventory of products for children, she says. "Because (KeentoWean.com) is weaning products solely, obviously the relevance is quite high," she says. KeentoWean.com site devotes a section to recipes, food suggestions, and helpful tips for weaning babies. Hine says she republishes the site at least once a week, a practice that can help in search engine rankings as engines like Google give more credit for fresh content.
Hine says she also requested reciprocal links with U.K. web sites and online forums for parents and children. That is also a tactic that can raise a site's search engine rankings, says Bill Leake, CEO of search marketing firm Apogee Search.
Achieving a high rank on a search term like "weaning products" is not as impressive as it would be on a more competitive term like "baby products," Leake says. He notes only 148 of the 2.9 million U.S. web pages in the Google index have the term "weaning products" in the title tag that describes the site, and presumably fewer in the smaller UK market. Nonetheless, he says, KeentoWean is doing many of the things that help bring a site up in search engine rankings.
While there are a lot of variables in how Google ranks each web site, and Google keeps its algorithms secret, Leake says roughly 20% of the ranking on a competitive phrase is based on the content on the site's pages and 80% on other factors, including the age of the domain, links to the site and other factors.
He says search engines value highly new content and links from well-established sites, or as he puts it, "Google likes a web site with new content and old links." Retailers can raise their rankings by asking others to link to them, such as the manufacturers of the goods they sell, Leake says.
KeentoWean did just that, Hine says. She also reached out to parenting forums and other baby and parenting sites requesting reciprocal links, and joined a number of those forums, posting a short description of her site where allowed. "I only targeted sites that were relevant to my products, that is, only baby/parenting-specific, and I always asked permission," she says.
Leake has one other tip for improving search engine ranking: Let others know how you want them to link to your site, for instance, making sure the most important term, such as "weaning products," is the phrase that is attached to the link. "Then the web site linking to you is not only voting for you being generally important, it's voting for you being specifically important for that keyword," he says.
A retailer can also ask customers to mention the site in blogs, with a link featuring the primary keyword. That works especially well when the product is something with an emotional appeal. "If these folks are selling products people are passionate about," Leake says, "they can probably get a lot of link love back from those customers."
A small online retailer that lacks brand recognition can get a big boost from high ...
Posted 02/20/17
We are now entering the third decade of the Amazon effect, and it is just ...
Posted 02/20/17
The Supreme Court is surely going to find this question right back on their doorstep next year."


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London - England's wicketkeeper-batsman Jonny Bairstow will miss next month's one-day series in India after being granted an extension to his compassionate leave due to a family illness.
Bairstow, who left before the final Twenty20 fixture in India before Christmas for the same reason, has been replaced in the squad by Joe Root.
The England and Wales Cricket Board said on Friday that Bairstow is "expected to return to the squad for the T20 and ODI tour of New Zealand beginning in late January."
Root made his Test and Twenty20 debuts for England against India earlier this month.
Bairstow is the third player to be withdrawn from the original touring party, joining rested duo James Anderson and Jonathan Trott.
England play a five-match ODI series in India before heading for New Zealand.
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ICMM will hold its next Congress, from 15-20 October 2017
The host museum is Chile's National Maritime Museum. Planning has already commenced for the Congress under the direction of ICMM Executive Council member and Director of the Chilean National Maritime Museum, Rear Admiral Cristian del Real.
It's my pleasure to communicate with you again via the quarterly Newsletter. Perhaps you are receiving this in your email inbox, or perhaps you are seeing it on our brand new website which just recently went live.Read more
ICMM brings maritime museum professionals together from all over the world for regular conferences, creating a strong network of maritime museums and people.Read more


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Evolution and the Common Law
By (author) Allan C. Hutchinson
Format: Hardback
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Evolution and the Common Law by Allan C. Hutchinson
Book DescriptionThis book offers a radical challenge to accounts of the common law's development. Contrary to received jurisprudential wisdom, it maintains there is no grand theory which will explain satisfactorily the dynamic interactions of change and stability in the common law's history. Offering original readings of Charles Darwin's and Hans-Georg Gadamer's works, the book shows that law is a rhetorical activity that can only be properly appreciated in its historical and political context; tradition and transformation are locked in a mutually reinforcing but thoroughly contingent embrace. In contrast to the dewy-eyed offerings of much contemporary work, it demonstrates that, like life, law is an organic process (i.e., events are the products of functional and localized causes) rather than a miraculous one (i.e., events are the result of some grand plan or intervention). In short, common law is a perpetual work-in-progress - evanescent, dynamic, messy, productive, tantalising, and bottom-up.
Buy Evolution and the Common Law book by Allan C. Hutchinson from Australia's Online Bookstore, Boomerang Books.
Book DetailsISBN: 9780521849685
(234mm x 156mm x 19mm)
Pages: 306
Imprint: Cambridge University Press
Publisher: Cambridge University Press
Publish Date: 4-Apr-2005
Country of Publication: United Kingdom
Other Editions...
Books By Author Allan C. Hutchinson
Toward an Informal Account of Legal Interpretation, Hardback (October 2016)
The book challenges all formalist accounts of legal interpretation and offers an 'informal' alternative.
Is Killing People Right?, Paperback (April 2016)
This book examines how the common law works through profiles of eight great cases.
Fighting Fair, Hardback (July 2015)
This book draws an extended analogy with military theory to propose a new model for legal ethics.
Laughing at the Gods, Paperback (January 2012)» View all books by Allan C. Hutchinson
This book showcases eight judges that exemplify judicial greatness and looks at what role they play in law and society.
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Author Biography - Allan C. Hutchinson
Allan C. Hutchinson is Professor and Associate Dean at Osgoode Hall Law School in York University. He has published on a variety of subjects including civil litigation, constitutional law, torts, jurisprudence, evidence, legal profession, and legal ethics. He was elected a Fellow of the Royal Society of Canada and awarded Osgoode Hall's inaugural Excellence in Teaching Award.
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Our guide to the world of food, drink and entertaining, The Menu serves up interviews with the world's most creative chefs, introduces the makers behind the scenes and the ingredients that will soon be landing on your restaurant table.
May 3rd, 2013
Episode 161 of 492 episodes
We visit the London Coffee Festival for the latest brews, meet possibly the most successful Norwegian barista of all time, Rasmus Helgebostad, and chat to world-famous Italian chef Massimo Bottura.
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Through Gates of Splendor Hardback
by Elisabeth Elliot;
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Through Gates of Splendor
Full Product Description
In 1956, five young men, including Elliot's husband, Jim, traveled into the jungles of Ecuador to establish communication with the fierce Huaorani Tribe, a people whose only previous response to the outside world had been to attack all strangers. The men's mission combined modern technology with innate ingenuity, sparked by a passionate determination to get the gospel to those without Christ. In a nearby village, their wives waited to hear from them. The news they received--all five missionaries had been murdered--changed lives around the world forever. Written while she was still a missionary in South America and at the request of the men's families, Through Gates of Splendor was Elisabeth Elliot's personal account of the final mission of these five courageous men. Filled with quotations from letters, material from personal journals, a wealth of photographs, and an epilogue update, this reprint of the original hardcover edition tells a lasting story of God's grace, unconditional love, and great courage. This story inspired the 2006 box office hit End of the Spear and is sure to inspire the next generation of servant believers.
Through Gates of Splendor by Elisabeth Elliot was published by Hendrickson in April 2010 and is our 18079th best seller. The ISBN for Through Gates of Splendor is 9781598564693.
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Details for Through Gates of Splendor
|Page last updated
|18th January 2017
|Author / Artist
|Elisabeth Elliot
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|24 mm
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|146 mm
|Product Code


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By Chris Carmichael The end of March is a great time of year for endurance athletes. There's so much enthusiasm in the air, so many incredible goals being set, and so many early-season triumphs to cheer about. For coaches, this is the time when we get to talk about race tactics and strategies, in addition…Read the full article
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4 Tour of Flanders Tips All Cyclists Can Benefit From
This Sunday I strongly suggest you find a live video feed of the Tour of Flanders. It's always a race worth watching, and if watching the Ronde van Vlaanderen doesn't inspire you to get out there and put in a storming Sunday ride, I don't know what will. I raced Flanders with 7-Eleven and…Read the full article
The Key to being Extraordinary
As sports fans we're accustomed to witnessing extraordinary performances across the entire spectrum of sports. But all those highlight reels are a double-edged sword. On one hand, highlight reels are inspirational. Many riders go out after watching an amazing cycling race like the Tour of Flanders, a stage of the Amgen Tour of California, or…Read the full article


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Running time: TBC
Directed by: Tom Harper
Written by: Jon Croker
Produced by: Simon Oakes, Richard Jackson, Tobin Armbrust, Ben Holden
Phoebe Fox
Jeremy Irvine
Helen McCrory
Oaklee Pendergast
As bombs rain down on London during the Blitz of World War II, a group of school children are evacuated with Eve, their young and beautiful schoolteacher, to the safety of the English countryside. Taken to an old and empty estate, cut-off by a causeway from the mainland, they are left at Eel Marsh House.
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The 666th shot took place on Friday 13th of December on the last day of shooting in the Eel Marsh House set at Pinewood.
Released worldwide from January 1st 2015!
UK - January 1st
USA - January 2nd
Hundreds of thousands of children were evacuated from London during World War II.
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