text: Biology - Ph.D. / Sc.D. http://hdl.handle.net/1721.1/7783 2017-03-01T18:21:06Z Optimal bioeconomic management of changing marine resources http://hdl.handle.net/1721.1/106966 Optimal bioeconomic management of changing marine resources Moberg, Emily Alison Marine populations are increasingly subjected to changing conditions whether through harvest or through broad-scale habitat change. Historically, few models have accounted for such trends over time, and even fewer have been used to study how trends affect optimal harvests. I developed and analyzed several models that explore, first, endogenous change caused by harvest and, second, exogenous change from factors (such as rising ocean temperatures) outside harvesters' control. In these models, I characterized the profit-or yield-maximizing strategy when harvesting damages habitat in a multispecies fishery, when harvest creates a selective pressure on dispersal, and when rising temperatures cause changes in vital rates. I explore this last case in both deterministic and stochastic environments, and also allow the harvester to learn about unknown parameters of the stock recruitment model while harvesting. I also develop an unambiguous definition of and describe a statistical test for a shift in a species' spatial distribution. My results demonstrate that optimal harvesting strategies in a changing environment differ in important ways from optimal strategies in a constant environment. Thesis: Ph. D., Joint Program in Oceanography/Applied Ocean Science and Engineering (Massachusetts Institute of Technology, Department of Biology; and the Woods Hole Oceanographic Institution), 2016.; Cataloged from PDF version of thesis.; Includes bibliographical references. 2016-01-01T00:00:00Z Autonomous replication of integrative and conjugative elements http://hdl.handle.net/1721.1/106738 Autonomous replication of integrative and conjugative elements Wright, Laurel D Mobile genetic elements facilitate movement of genes, including those conferring antibiotic resistance and other traits, between bacteria. Integrative and conjugative elements (ICEs), also known as conjugative transposons, are a large family of mobile genetic elements that can transfer between neighboring cells. ICEs are found integrated in the chromosome of their host bacterium, where they are transmitted to daughter cells by chromosomal replication and cell division. Under certain conditions, ICE DNA will excise and form a circular plasmid-like intermediate. It was previously thought that ICEs were incapable of autonomous replication. However, my research, along with the work of others, shows that ICEs can replicate autonomously, and that many ICEs utilize a rolling circle replication mechanism. Plasmids and phages that use rolling circle replication encode a single strand origin (sso) that enhances priming of DNA synthesis. We identified a functional single strand origin, sso1, in the integrative and conjugative element ICEBs1 of Bacillus subtilis. Genetic analyses indicated that ICEBs1 uses sso1 and at least one other region for second strand DNA synthesis. Sso activity was important for autonomous, rolling circle replication of ICEBs1 in host cells, and for stable acquisition of the element in new host cells. I also showed that the broad-host range ICE Tn916 replicates autonomously by a rolling circle mechanism. Replication of Tn916 was dependent on the relaxase encoded by Tn916 orf20. The origin of transfer of Tn916, oriT(916), also functioned as an origin of replication. I found that the relaxase (Orf20) and the two putative helicase processivity factors (Orf22 and Orf23) encoded by Tn916 likely interact in a complex to facilitate replication. Lastly, I identified a functional single strand origin of replication (sso) in Tn916 that I predict primes second strand synthesis during rolling circle replication. The importance of autonomous replication by rolling circle in the ICE lifecycle and horizontal gene transfer processes is discussed. Thesis: Ph. D., Massachusetts Institute of Technology, Department of Biology, 2016.; Cataloged from PDF version of thesis.; Includes bibliographical references. 2016-01-01T00:00:00Z Studies of amino acid sensing by the mTORC 1 pathway http://hdl.handle.net/1721.1/106737 Studies of amino acid sensing by the mTORC 1 pathway Wang, Shuyu, Ph. D. Massachusetts Institute of Technology The mTOR complex 1 (mTORC 1) protein kinase is a master growth regulator that responds to multiple cues from the local and systemic environment surrounding the cell. Nutrients and growth factors are both required to activate mTORC 1 and to promote growth. While the mechanisms of growth factor signaling have been reasonably well established, we have only begun to unravel in recent years how amino acids signal to mTORC 1, thanks in large part to the identification of the Rag GTPases, which recruit mTORC 1 to the lysosomal surface for catalytic activation, and of the regulators of Rag function. An ultimate goal is to uncover the biochemical basis of the sensing event that triggers this signaling cascade in the first place: which amino acid(s) are sensed and how? Toward this end, we characterize in detail the amino acids required to fully activate mTORCl signaling in HEK-293T cells and identify SLC38A9 as a Rag-interacting amino acid transporter that may serve as an arginine sensor at the lysosome. Finally, we discuss the many open questions that remain to be studied regarding the mechanisms and logic behind amino acid sensing by the mTORC 1 pathway. Thesis: Ph. D., Massachusetts Institute of Technology, Department of Biology, 2016.; Cataloged from PDF version of thesis. "September 2016."; Includes bibliographical references. 2016-01-01T00:00:00Z Small-molecule inhibition of general transcriptional regulators in cancer http://hdl.handle.net/1721.1/106736 Small-molecule inhibition of general transcriptional regulators in cancer Reddy, Jessica Transcription is frequently deregulated in cancer, but targeting of transcriptional processes for cancer therapy has thus far been limited to nuclear receptors. Recent studies, however, have suggested that inhibitors of various general transcriptional regulators can be used in cancer therapy because expression of some oncogenes is disproportionately sensitivity to these inhibitors. Here, I describe the cellular and molecular effects of inhibiting a general transcriptional regulator, CDK7, in T-cell acute lymphoblastic leukemia (T-ALL) cells. Because tumor cells commonly evolve resistance to individual therapies, I have also investigated the potentially synergistic effects of combining two compounds that target transcriptional regulators - the CDK7-inhibitor THZ1 and the BRD4-inhibitor JQ1 - and suggest a model describing the molecular basis of the synergistic effects I observed. My research provides insight into the effects of these inhibitors of general transcriptional regulators on tumor cell behavior and gene expression programs. Thesis: Ph. D., Massachusetts Institute of Technology, Department of Biology, 2016.; Cataloged from PDF version of thesis.; Includes bibliographical references. 2016-01-01T00:00:00Z


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Showing 1-24 of 44 items found in Outdoors & Play
- Sort by:
Arlington Greens Golf Course consists of an 18 hole, par 72 facility with a length of approximately 7,200 yards. The terrain is gently undulating to near level. Each hole has yardages for gold, blue, and white tees that point directly down the fairway with little misdirection. Fairways are irrigated with a double row irrigation system which has recently been upgraded. Fairways consist almost entirely of Bermuda grass.
CITY:Granite City
Just outside of Edwardsville, Bilbrey Farms is home to exotic animals and trained birds. Come feed the animals or stay at the bed and breakfast.
Cahokia Mounds State Historic Site
Illinois' only United Nations World Heritage Site. This 2,200-acre site preserves the central section of the largest prehistoric Indian city north of Mexico. An Interpretive Center presents a coherent account of this sophisticated prehistoric culture. Climb Monk's Mound, see the film and life-size village. Don't miss annual events that focus on Native American culture.
Spend the day tackling go-karts, miniature golf, batting cages, bumper boats and a video arcade.
Route 66 runs through the island which connects Illinois and Missouri. East side of the Mississippi River.
CITY:Pontoon Beach
Boasting some of the largest greens in the Midwest, the 18-hole Clinton Hill has matured into one of the finest public golf courses around, with a great blend of par 3s, 4s and 5s.
Drost Park features a 7-acre lake, pavilions, 1-mile walking trail, boat ramp, playground, and restroom facilities. The University of Illinois' Master Gardeners keep it seasonally beautiful.
Located in Maryville, this facility has an indoor arcade, batting cages and lots more fun for kids. Alfonzo's Restaurant is right next door for pizza lovers.
Tee it high and let it fly into open fairways on one of the Midwest's best golf courses. The front nine is a Scottish-style links layout with native prairie grasses and wild flowers. Grand oaks line perfect fairways on the backside with truly one of the best 9-holes in the St. Louis area. Expect smooth rolling large greens when you play Far Oaks that are consistently rated the best public course greens in the area, you won't be disappointed. Complementing the golf course, the Clubhouse Grill features a casual club setting with delicious lunch options.
Fox Creek Golf Course is an18 hole course which offers all levels of golfers a real challenge to their playing skills. Rolling terrain, wooded bluffs, winding creeks and seven lakes make this course scenically beautiful as well as challenging.
A great place to spot water birds, fish, boat, or play a round of golf. The park covers 1,125 acres, including two lakes and a wetlands area.
CITY:East St. Louis
Fults Hill Prairie/Kidd Lake Marsh State Natural Area
This natural area comprimises 532 acres of forest, prairie and flowering trees, with a trail and pond.
CITY:East St. Louis
Gateway features mini-golf, go-karts, an arcade, bumper boats, a kiddie track and Rudy's Restaurant.
As the world's tallest fountain, the Gateway Geyser Fountain reaches 627 feet in height, and is centered in a pond that holds five million gallons of water.
CITY:East St. Louis
Gateway National offers an 18-hole, par 71 course made up of rolling links, separated by gentle mounds that meander through lush, green pasturelands.
Home to newly added in-line hockey rink. Sitting on 30 acres, five tennis courts, soccer field and basketball court, walking track 4 to 10 mile.
Grand Marais Golf Course takes golf to new heights, and we are not just talking about the spectacular views you'll enjoy while playing our course. Includes an on-site restaurant and pro shop.
28 sites, lake fishing, boating, tent camping
CITY:Granite City
Indian Mounds Golf Course, formally know as Tee-Up Golf Course, is located in Fairmont City, Illinois. It features 3,381 yards of golf with 5 par 4's and 13 par 3's. Designed by Dave Murray and Jan Freiberg in 1995, our course features narrow, tree-lined fairways, severely undulating bent grass greens in addition to water hazards on many holes. The signature hole is #7, a 183-yard, par 3, requiring a tee shot to a peninsula green.
CITY:Fairmont City
This softball field is located in Woodland Park.
77 sites, electricity, water, sewer, showers, reservations.
CITY:Granite City
A 5,000 sq. ft. laser tag arena and a 2,500 sq. ft. game arcade is conveniently located by hotels and restaurants off I-64.
For a closer look at river traffic on the Mississippi, go by the lock and dam where Ol' Man River is still an important way to move freight in the United States.
CITY:Granite City
The 24-acre park has a pavilion, walking trails, and many other amenities. It is also the site of the Veterans of All Wars Memorial and the September 11 Memorial.

subset: commoncrawl


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free Blog submission...
- Status Closed
- Budget $5 - $10 USD
- Total Bids 16
Project Description
I need a coder to find out free blog website where I can submit my blog free Like [url removed, login to view], [url removed, login to view] and so on... I will provide a blog. You just need to submit my blog. Please let me know how much submission you can provide? Happy bidding..
## Deliverables
1) Complete and fully-functional working program(s) in executable form as well as complete source code of all work done.
2) Deliverables must be in ready-to-run condition, as follows (depending on the nature of the deliverables):
a) For web sites or other server-side deliverables intended to only ever exist in one place in the Buyer's environment--Deliverables must be installed by the Seller in ready-to-run condition in the Buyer's environment.
b) For all others including desktop software or software the buyer intends to distribute: A software installation package that will install the software in ready-to-run condition on the platform(s) specified in this bid request.
3) All deliverables will be considered "work made for hire" under U.S. Copyright law. Buyer will receive exclusive and complete copyrights to all work purchased. (No GPL, GNU, 3rd party components, etc. unless all copyright ramifications are explained AND AGREED TO by the buyer on the site per the coder's Seller Legal Agreement).
## Platform
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text:
Conversation Between DoctorWhoLuver and RowdyBetta
Showing Visitor Messages 11 to 20 of 21
- 06-25-2013 01:47 PM - permalinkRowdyBettaYay!! :D I can't wait to see it!!
Is there anything I can do for YOU? :3 I can draw horses, dogs, most birds, some people (depends on who)- oh! :D I can draw the Doctor! Do you have a fav Doctor?? (I haven't watched the show but I've seen pics and heard ppl talk about it.)
Here's one of my most recent. Its Richard Dean Anderson as MacGyver
h ttp://farm6.staticflickr.com/5457/8778831303_b61b5826df_z.jpg
- 06-25-2013 12:41 PM - permalinkDoctorWhoLuverOkay, I'll do the best I can:)
- 06-25-2013 12:36 PM - permalinkRowdyBettaht tp://www.bettafish.com/album.php?albumid=10050&pictureid=65434
Here's one :3
- 06-25-2013 12:14 PM - permalinkDoctorWhoLuverYeah, sure:) Do you have a picture? I use GIMP
- 06-25-2013 12:04 PM - permalinkRowdyBettaEep! Really!!? :D Geese, you're awesome! XD I could do one for you in return. :3 I haven't drawn any fish in years but I have a few examples on here.
If it's alright, could you do one of Count Manzeppi? :3 I don't want to trouble you or anything, but they just look way to cute! What program do you use?
- 06-25-2013 11:54 AM - permalinkDoctorWhoLuverNever thought of it, but I'll gladly do one:)
- 06-25-2013 12:28 AM - permalinkRowdyBettaDo you do free commissions on here?
- 06-25-2013 12:26 AM - permalinkDoctorWhoLuverThank you :D
- 06-24-2013 11:27 PM - permalinkRowdyBettaWow, really!? They look awesome! ^.^
- 06-24-2013 11:23 PM - permalinkDoctorWhoLuverI made them:)


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The Langley Chess Club is proud to announce the 11th annual Langley Open! Please click here to view the details and register online:
The Langley Chess Club is proud to announce the 11th annual Langley Open! Please click here to view the details and register online:
Congratulations to Hugh Long, the 2015 Club Champion. This year's tournament was a 6-player round robin, in which Hugh scored 4.0/5.0 for sole first place.
This is not the first time Hugh has been Club Champion. He also held the title a number of times between 1996 and 2003.
The results will be posted once the tournament is CFC rated.
The Langley Chess Club is pleased to announce a tournament to remember and acknowledge our friend and fellow Chess player, Peter Yee. Peter was a long time member of the Langley Chess Club and played tournaments there frequently for many years.
All profits from this tournament will be donated to the VGH & UBC Hospital Foundation In Memory of Peter Yee for the Leukemia/BMT program.
Please see the full details on the tournament page by clicking here: Peter Yee Memorial
The Langley Correspondence 2014 is now complete. The tournament started on October 1, 2014 with seven players. Click here to see the tournament details and full results and standings.
Congratulations to Savvas Kyriakides who took first place by quite a good margin, and receives a 1-year Gold Membership to chess.com.
2014 brings the Langley Chess Club an all new Champion, and our youngest ever! Congratulations to Neil Doknjas for an impressive victory against a solid lineup of players, many who have won the Championship in previous years.
2014 Club Champion Neil Doknjas with Club President Hugh Long
This 2014 event had an attendance of 46 players. Slightly down from our previous record of about 60 players, but still a great turnout.
Congratulations to this year's winners!
1st: Bindi Cheng
2nd/3rd: John Doknjas, Joshua Doknjas, Savvas Kyriakides
Best U2000: Luke Pulfer, Robin Yu, Paul Leblanc, Karl Cui
Best U1800: Hugh Long, Robert Hamm, Robert L Barron, Matthew Geng
Biggest Upset: Edward Enns
The June Swiss has been completed, and results can be found on our Club Results page as well as on the CFC website.
Congratulations to Charlie Jarquin and Steven Buchi for taking first place. Steven Buchi also took the best U1600 prize, which is an excellent result amongst this group of club players.
The next tournament will be the 2014 Langley Open. Get yourself registered today!
The 2014 April Swiss is underway, with 14 registered players. You can view the cross table on the Schedule Page, along with round-by-round pairings.
Summer is a busy time, and events at the Langley Chess Club vary depending on participation. Sometimes we hold a Monday-night Swiss during the summer. Otherwise, it's open for drop-in games. Watch for an announcement on the Schedule page for closures during the Summer months.
Things kick off again at the end of August with the Langley Open. Watch for an announcement on that as well, and subscribe to our mailing list to be notified by email.
The Autumn Swiss has been rated by the CFC, and the results posted to our Club Results page.
Congratulations to John Doknjas for taking first place, scoring 4.5/5.0, winning the $50 prize. Amir Fazel, Neil Doknjas, and Andrew Hoyer tied for Best U1600 with 3.0/5.0, and split the $25 prize.
The 2013 Club Championship was held during the month of September and October. John Doknjas, last year's Champion, successfully defended his title, scoring 4.5/5.0, a full point ahead of second place.
Full results of the tournament can be viewed on the CFC website: 2013 Langley CC Ch


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You can post a new question from the country page to which the question is relevant to, or at the bottom right hand of this page.
to post a new question or answer excisting ones
Please don't spam this forum with your new surf camp / charter / villa / surf school. Go to SurferDream.com and list your business there for free.
The GlobalSurfers forum has been the leading surf travel resource for over 18 years, so keep it friendly and relevant. Happy posting!
Anyone heard of these before? Shark Deterrent Bands« on: September 25 2010 14:09:00 »
Hello Forum,
I apologize if this is seen as Spam but i wanted to share a new product that recently has hit the market, it a Neoprene band that emits an artificially induced magnetic field that interferes with the " "Ampullae of Lorenzini" that Sharks and Sting Rays have. When a Shark approaches the Magnetic filed produced by the Shark Shocker, it becomes disoriented and is repelled and deterred from staying near this magnetic field. Check out the website at http://www.thesharkshocker.com
RE: Anyone heard of these before? Shark Deterrent Bands« Reply #1 on: September 29 2010 07:09:00 »
Yes! However, whilst your hobnob marketing monkeys claim that they deter sharks, scientist maintain that your wrist bands (any wristbands) will attract gays ugayfuk
RE: Anyone heard of these before? Shark Deterrent Bands« Reply #2 on: April 01 2011 03:04:00 »
Interesting product be nice to here of any proven use of. Testing in pointer country of SW WA or South Aussie be interesting.
RE: Anyone heard of these before? Shark Deterrent Bands« Reply #3 on: April 01 2011 15:04:00 »
It seems Beverley Hamilton had a watch on the arm what got attacked and I saw a photo of her having some thing shiny on the arm left while surfing.


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Wooden photo frames to personalise and display! Decorate using acrylic paints or Deco pens and insert a favourite photo. Makes a perfect gift or keepsake. Fits standard 6 x 4 photos and includes a rod for standing.
Thank you for visiting Wooden Photo Frames - Pack of 4 on hundredsofgiftideas.co.uk
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text: OverviewBack to top Heaven Sent - Hangover Protection - 15 Capsules Item# :103311UPC# :759051060166 Brand:Heaven Sent Size/Form:15 Capsules Servings:15 Dosage:1 Capsule(s) Heaven Sent - Hangover Protection 568 mg. - 15 Capsules Hangover Protection by Heaven Sent have been formulated to help 17 common hangover symptoms including headache, nausea and fatigue. Hangover Protection will stop a hangover before it starts. Hangover Protection can reduce hangover symptoms up to 70%, help regulate alcohol metabolism and protect skin from alcohol damage.


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text:
Red Hat Bugzilla – Bug 354601
open animations applied to menus
Last modified: 2007-11-30 17:12:20 EST
Open animations are applied to firefox menus since the upgrade to 0.6.0.
Apparently fixed in latest git. The bug on their bugzilla is here:
This patch is already part of the 0.6.0 release and therefor included in the
current package.
Also what was the last version that worked for you? (full rpm version please)
Whatever the previous 0.5.2 based one was, probably
compiz-fusion-0.5.2-10.09b700.fc8. Are you saying you're not having the problem?
I have it with both intel and nvidia hardware.
This build should fix it:
Please test it and report back.
With this version installed, compiz won't run at all for me. Does it for you?
I'm x86_64 with intel hardware.
continuity> compiz --replace --ignore-desktop-hints glib gconf
compiz (core) - Fatal: GLX_EXT_texture_from_pixmap is missing
compiz (core) - Error: Failed to manage screen: 0
compiz (core) - Fatal: No manageable screens found on display :0.0
If I revert to the previous version currently in the repos and restart the X
server, it works fine. It doesn't seem to make much sense bit that's what happens.
This is weird, does it also happen when you unload the workarounds plugin?
also try http://koji.fedoraproject.org/koji/taskinfo?taskID=217521 once finshed
The above failed, please try this one:
Are you sure that the new build is causing this? This looks completely unrelated
to the plugins. Can you reproduce it?
The compiz-fusion-0.6.0-5.fc8 build that completed this morning works correctly
and seems to fix the bug for me.
This is the one I have installed:
Ok, thx for the report and the quick testing.
The package has been tagged for f8-final and should hit rawhide soon.


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