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The Alzheimer disease (AD) brain is characterized by two types of protein aggregates, neurofibrillary tangles (NFTs), comprised of hyperphosphorylated tau, and amyloid plaques, comprised of amyloid-? (A?). Clinically, AD patients show a progressive deterioration of memory and other cognitive functions. Recent evidence points to soluble A? as an excellent candidate for the initial trigger of memory loss;however, the molecular mechanisms underlying A? -induced cognitive decline remain elusive. In our preliminary studies, we have identified the mammalian target of rapamycin (mTOR) as a potential molecular link between A?, tau and cognitive decline. Additionally, we show that A? oligomers increase mTOR signaling, an event mediated by the ?2 adrenergic receptors (?2ARs). To identify the mechanistic link between mTOR signaling and A?, tau and cognitive decline, three Specific Aims are proposed:
Specific Aim 1 will test the hypothesis that the accumulation of A? oligomers increases mTOR activity by a mechanism mediated by ?2ARs. mTOR plays a key role in regulating protein homeostasis;thus, unveiling the molecular pathways leading to its deregulation in AD will lead to a better understanding of the disease pathogenesis. Here we will dissect the molecular pathways that link the A? accumulation to changes in ?2ARs/mTOR signaling.
Specific Aim 2 will test the hypothesis that the A? -induced increase in mTOR signaling further increases A? pathology and exacerbates cognitive decline. Our preliminary data show that mTOR signaling is increased in 3xTg-AD and Tg2576 mice. Additionally, we show that reducing mTOR signaling with rapamycin, a selective mTOR inhibitor, rescues the early neuropathological and behavioral phenotypes in 6-month-old 3xTg-AD mice. Growing evidence shows that rapamycin may have mTOR-independent effects. To directly address the role of mTOR in AD, we will use a genetic approach and knockout mTOR in the brain of the Tg2576 mice.
Specific Aim 3 will test the hypothesis that the increase in mTOR signaling directly contributes to the tau pathology. Our preliminary data show that restoring mTOR signaling in the 3xTg-AD mice suffices to reduce A? and tau pathology. However, the tau pathology in these mice is highly dependent on A? levels;therefore, it remains to be established whether the effects of restoring mTOR signaling on tau pathology are mediated by a direct interaction between mTOR and tau or are simply due to a decrease in A? levels. Using a mouse model overexpressing wild type tau, we will use genetic and pharmacological approaches to decrease mTOR signaling and test the mechanistic link between mTOR signaling and tau pathology. Overall, the proposed Specific Aims will elucidate the underlying molecular pathways linking A?, tau and cognitive decline. The identification of the pathways that lead to cognitive decline may point to new therapeutic targets.
Alzheimer disease is the most common form of dementia among the elderly and the seventh leading cause of death in the United States. Our studies are aimed at understanding the molecular basis underlying memory loss and cognitive in AD decline and will facilitate the identification of potential therapeutic targets for this insidious disorder.
|Orr, Miranda E; Salinas, Angelica; Buffenstein, Rochelle et al. (2014) Mammalian target of rapamycin hyperactivity mediates the detrimental effects of a high sucrose diet on Alzheimer's disease pathology. Neurobiol Aging 35:1233-42
|Wisely, Elena V; Xiang, Yang K; Oddo, Salvatore (2014) Genetic suppression of ?2-adrenergic receptors ameliorates tau pathology in a mouse model of tauopathies. Hum Mol Genet 23:4024-34
|Caccamo, Antonella; De Pinto, Vito; Messina, Angela et al. (2014) Genetic reduction of mammalian target of rapamycin ameliorates Alzheimer's disease-like cognitive and pathological deficits by restoring hippocampal gene expression signature. J Neurosci 34:7988-98
|Branca, Caterina; Wisely, Elena V; Hartman, Lauren K et al. (2014) Administration of a selective ?2 adrenergic receptor antagonist exacerbates neuropathology and cognitive deficits in a mouse model of Alzheimer's disease. Neurobiol Aging 35:2726-35
|Caccamo, Antonella; Magri, Andrea; Medina, David X et al. (2013) mTOR regulates tau phosphorylation and degradation: implications for Alzheimer's disease and other tauopathies. Aging Cell 12:370-80
|Majumder, Smita; Caccamo, Antonella; Medina, David X et al. (2012) Lifelong rapamycin administration ameliorates age-dependent cognitive deficits by reducing IL-1ýý and enhancing NMDA signaling. Aging Cell 11:326-35
|Majumder, Smita; Richardson, Arlan; Strong, Randy et al. (2011) Inducing autophagy by rapamycin before, but not after, the formation of plaques and tangles ameliorates cognitive deficits. PLoS One 6:e25416


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Does Your Business or Practice Need More Leads, Sales, Repeat Business, and Profit?
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Choose the Ultimate "Done For You" Marketing Management or Custom Services. Getting results for you is our top priority. We specialize in Internet Marketing and bring broad and deep marketing expertise to help you build your business.

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Tag Archives: Travis Wall
The Shaping Sound Tour Premieres Tonight!
It's finally here! The premiere of Shaping Sound's tour, that is. We've been obsessed with this company—full of so-beautiful-we-can't-stop-looking-at-them commercial … More »
10 Dance-y Instagrammers to Follow
Instagram is basically a dance-lover's paradise. Dancers are all about visuals, so a photo-sharing app is our idea of a … More »
Travis Wall Spills About the Shaping Sound Tour
Remember when you first saw Travis Wall's choreography on "So You Think You Can Dance"? What about when you swooned … More »
Dance Moms We Love
To celebrate Mother's Day (May 12), we're highlighting five well-known dancer moms and their dancing children. Their love of the … More »
One-Girl Revolution
Kathryn McCormick's dance life seems pretty fairytale-esque: The 22-year-old native of Augusta, GA, was the top girl on "So You … More »
10 Things We Learned From the "All the Right Moves" Season Finale
"You look so pretty tonight. Did you get that in jail?" —Nick Lazzarini, Voice of Reason, "All the Right Moves" … More »


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2014 Canadian Paralympic Bonus Fund
$7,514 of $10k goal
Raised by 77 people in 36 months
Robb Price Calgary, AB
Canadian Olympic athletes get $20,000 for Gold, $15,000 for Silver and $10,000 for Bronze and PARALYMPIC Athletes get $0. Not anymore! DeliverGood will give Canadian PARALYMPIC Athletes $200 for Gold, $150 for Silver and $100 for Bronze. Please help contribute to increase these bonuses! Any support you can provide would be very much appreciated. An athlete is an athlete! Let's do this Canada!!
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of all the people who are worthy of our support, paralympic athletes are!!


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Three months after he was let go by Gold's Gym International (GGI), Joel Tallman created a new company with the owners of former Gold's operator American Club Systems (ACS).
Tallman, along with ACS owners Charlie Lindsey and Tim Goodwin, have collaborated on FIT Brands, an umbrella of fitness concepts that includes ACS, the newly branded Max Fitness clubs and Club Administrative Services, which provides billing and collection services specifically for fitness clubs.
Tallman said he had many opportunities to consider after leaving Gold's.
"Several of the opportunities that I had prior to accepting this position actually may be part of our plans going forward," Tallman said by phone from Atlanta before boarding a flight to his home in Seattle.
Tallman was the senior vice president of franchising and global operations for Irving, TX-based GGI, which announced his departure on June 14. Before joining Gold's in 2000, Tallman was an area director at Bally Total Fitness, Chicago.
"I've been in the business for 27 years, and 25 of them were with two companies," Tallman says. "It really gave me an opportunity to see what was out there, to see what the opportunities were. It was a great opportunity to sit down and have great discussions with several groups and then make a decision. It was really important to work with good people, and I'm very pleased to be able to work with Tim and Charlie and some of the people that are coming on board."
Tallman says he began forming the concept of FIT Brands "the day I wasn't with Gold's." He compares the structure of FIT Brands to that of Louisville, KY-based Yum! Brands, which has Pizza Hut, Taco Bell and KFC in its portfolio, among other fast-food restaurants. Not all of the clubs formed in FIT Brands will be under the Max Fitness brand, Tallman says.
"I really designed this company to be kind of the Marriott of fitness franchising in that there's many different Marriott concepts," he says. "The franchisee can really enter the marketplace in a lot of different ways."
ACS, a fitness club development and consultation company based in Columbus, GA, has recently rebranded its Gold's Gyms to Max Fitness in both Columbus and Auburn, AL. There are currently nine Max Fitness clubs in operation, with the remainder in south Texas and Baton Rouge, LA. The company projects it will have more than 200 Max Fitness, Max Fitness Elite and Max Fitness Express clubs in operation within the next two years.
"This is just the beginning of what we see as a tremendous opportunity to align new industry innovators with companies that have set their roots deep in fitness," Lindsey says. "We're bringing it all together under FIT Brands to ensure we consistently provide the highest quality results for our clients—whether that's helping our members reach their potential or our business customers meet their goals."
Tallman, Lindsey and Goodwin are all partners in FIT Brands. Lindsey calls Tallman, who will serve as president, the "driving force" of the company.
"He's a visionary who is at once creative and pragmatic," Lindsey says. "In our world, where operations and constant innovation come together every day, that's a delicate balance, and Joel does it like nobody else in the industry."
Although the FIT Brands' revenue model will be driven primarily by corporately owned clubs, franchising will be an important part of the company, Tallman says.
"One thing that I really did take away from Gold's Gym was it allowed me to understand the relationship that could be had and really the fellowship, the fraternity of the Gold's Gym franchisees," Tallman says. "I want that. Franchising will be part of this company because of the family, because of the camaraderie."
Tallman becomes another in a long line of operators with ties to Gold's who have broken away from the company and created a new brand. Royce Pulliam (Urban Active), Kirk and John Galiani (Onelife Fitness) and Jeff Skeen (Fitness Connection) are all former Gold's operators who now run their own brands.
"There's just a life cycle to a business, and I think it's a very natural thing for a business that's going into a growth mode to look at flying its own flag," Tallman says, "or in some cases, multiple flags, like we will. I don't really think it's a commentary on Gold's Gym. You look at all those organizations, and they're doing some of their own brands and continuing to grow."
Tallman says it was Gold's decision to remove him from the company. When asked specifically about the future of Gold's, Tallman took the high road.
"The only thing I'm going to look back on in my last 11 years is really what I drew from the franchisees," Tallman says. "That was just special, and it will always be. As long as I'm in this industry, I don't know if I can recreate the relationship with the franchisees, but I certainly will try. Gold's Gym was a great stepping stone for my career, and I'm thankful for that opportunity. But now, I'm excited about what's ahead."


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Hotel Het Gheestelic Hof
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Belgium's beauty, Bruges
Little to no expectations of what this town would bring we were very pleasantly surprised. Super cute canal town, so getting spoiled with canals. Other than the core of the town, which is maybe 3-4 square blocks, this place is almost like a ghost town it is so quiet. Almost resembling a small scale Amsterdam with the style of houses and canals, this town is home to likely the most chocolate shops per capita and amazingly ...
The Low Countries
... bikes made available with our accommodation, with us. (We are a little under confident as bike riders here - I'm sure the locals wouldn't be too happy with our pace!)
Monday and the sun shone - at least for an hour or so. We set out for regional villages of Broek and Marken in the Waterland district, about 20kms north. Both are delightful little villages. By the time we arrived in Markem, the heavens opened so we sought shelter, yes, in the clog factory. Here, I put ...
A Belgian Tour: Medieval and Modern
... was amazing! We walked into the main square, called the Markt, and marvelled at the beautiful buildings with their step roofs. First thing on the agenda was a canal cruise. The canals in Brugge are certainly not as elaborate a Venice, but we had a very nice trip through the city with beautiful views of buildings, bridges and back alleys. We wandered back to the main square which was unfortunately a bit cluttered by the stands ...
... beers and a final full beer of your choice, the beer tasting seemed good value. For me, it was especially good value as I got it for free! When I told the tour guide in Cologne I was going to Brugge, he said I could have the beer tasting for free if I did the walking tour. The offer was accepted without hesitation. The guy running the tour was the same guy that had done the walking tour just the day before. The samples were sized at one bottle between 3 people. But somehow ...
3 cities in one day
... s was the meeting place to see Joseph and Valentina, it was lovely to see their familiar faces. Joseph recommended some beers for us to try which was really fun. He also shouted us a delicious meal at a restaurant overlooking the water. It was great to catch up and get some travel tips and information about the country we were in. Tired, we returned in the evening to our hotel, dreading leaving tomorrow. We do however, have the Netherlands to look forward ...


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Dear Patients,
since April, my colleague and specialist B. Myndiuk takes over your medical treatment in this practice. He has worked as senior physician ("Oberarzt") in clinics in Berlin and Munich. With his experience in the fields of gynecology and obstetrics, he offers you a great professional and individual care. Please click HERE to make an appointment online.
For more information about our services, please go to the German website. Do not worry in case of language barriers: we are treating many international patients for years and offer you assistance in English.
Best regards,
Dr. med. Waltraud Obst-Tirmizi, MD
Dear Patients,


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Photos: Unlikely pair plan to attend homecoming dance together
Ariel Nelson wants to take her friend Noah Weber as homecoming date Read more: http://www.wtae.com/news/an-unlikely-pair-16yearold-woodland-hills-junior-wants-to-take-8yearold-to-homecoming-dance/27140526#ixzz3ACUmazgQ
When Noah Weber was born, doctors told his parents to prepare to say goodbye. He has a rare, congenital heart defect, according to his mother, Virginia. At 8 years old, he has had four major open heart surgeries.
"He's had a lot of mental health issues through the years too where he was very aggressive and angry," said Virginia. That's where an unlikely companion comes in.
"She has brought out a very special, loving little boy that was inside of him. She's so wonderful," said Virginia, speaking graciously about 16-year-old Ariel Nelson.
Nelson attends Woodland Hills High School. She took dance lessons with Noah's sisters, and through birthday parties she came to meet Noah. Noah was smitten right away.
"It all started like 'Oh, that's your girlfriend,'" said Nelson. At first it was a joke, but Noah has since referred to her as his girlfriend -- and it's now been more than one year. "I mean, I couldn't pass it (this friendship) up because he's just so sweet and energetic and it surprises me that he can do what he does with the condition he has," said Nelson.
Noah takes his role as boyfriend seriously. He bought Ariel a ring, a necklace and even surprised her at her dance recital.
Ariel is focused on high school this year, but always has her young friend on her mind. The homecoming dance in October is something she looks forward to, and she wants Noah to be her date.
"Everyone should deserve to get a chance to go to their homecoming and dress up for school," she said. "We don't know what his condition is going to be in the future, so I said, 'Hey I'm going to be a junior this year, why not take him?'"


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We are filing this one under "best thing ever." Ralph Fiennes, who played Voldemort in the "Harry Potter" films just read erotic Potter fan fiction on live television … in his pajamas, with hook-up music in the background.
A lot of us miss the "Harry Potter" books and films, now that the series is complete. Some of us choose to re-read and re-watch. Some of us have moved onto the "Hunger Games" series. Some of us weep into our butter beer. Others … well, they write erotic fan fiction starring Voldemort to deal with the pain.
On Bravo's "Watch What Happens: Live," a pajama-clad Fiennes was introduced to this literary weirdness and convinced to read it aloud. Host Andy Cohen said, "Here's one for all you 'Harry Potter' fetishists. I'm gonna make your
dreams come true and have Lord V. himself read something aloud." Watch the slightly NSFW video below and marvel at the weirdness.


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- Sugarvine
- > Blackpool and Fylde
- > Restaurants
- > Bispham Restaurants
- > Takeaway
Takeaways in Bispham
For regular updates on the best dining Deals in Blackpool and Fylde subscribe to our Blackpool and Fylde Special Offers Newsletter.
Looking for Takeaways in Bispham? Find them on the leading Blackpool and Fylde restaurant guide. Discover the best Takeaways in Bispham with links to restaurant websites, online menus, restaurant photos, special offers, location maps & much more.
If you can't find the venue you're looking for add it here.
273 The Fishery273 Devonshire Road, Bispham, FY2 0TN | 01253 351670
Bellagio's Diner, Pizza & Takeaway238 Queens Promenade, Bispham, FY2 9HA | 01253 355237
Eastern Spice95 Bispham Road, Bispham, FY2 0NR | 01253 500935
Indian Orchard265a Devonshire Road, Bispham, FY2 0TJ | 01253 350566
New Harmany Chinese Restaurant319 Red Bank Road, Bispham, FY2 0HJ | 01253 592760
Seniors Fish and Chips2 All Hallows Road, Bispham, FY2 0AU | 01253 591144
Sunam Tandoori93-99 Redbank Road, Bispham, FY2 9HZ | 01253 352572
Welcome Chinese TakeAway265b Devonshire Road, Bispham, FY2 0TJ | 01253 593347


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Follow @SCTScourtstribs
There are new standards of service for victims and witnesses involved in court cases. The SCTS is committed to providing high-quality services and are holders of the CSE award - Customer Service Excellence. If our service falls below these standards or you would like to make a complaint, please tell us. Our complaints procedure shows how to make a complaint and what you can expect from us. You can download a PDF copy of the complaints procedure here.
The Courts Reform (Scotland) Act 2014 heralds the most significant changes to Scotland's civil justice system in generations and continues the programme of reform of Scotland's courts implementing many of the recommendations of the Scottish Civil Courts Review, led by principal reviewer Lord Gill, commissioned in 2007. More information is available on the new All-Scotland Sheriff Personal Injury Court and the Sheriff Appeal Court.
The SCTS is recommending both a new approach to ensure children and vulnerable witnesses are protected from further trauma while giving evidence and radical digital transformation of the summary criminal justice system.
Evidence and Procedure Report - Next Steps
Simple Procedure replaces the current small claims procedure and part of the summary cause procedure. It is a court process designed to provide a speedy, inexpensive and informal way to resolve disputes where the monetary value does not exceed £5,000.
If you would like read more please click HERE
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We would like to invite you to be a part of an important opportunity as an exhibitor at our biennial conference "2016 Update in Gastroenterology & Hepatology" at the Hilton Birmingham Perimeter Park Hotel in Birmingham, Alabama on September 30 – October 1, 2016 – presented by The University of Alabama at Birmingham Division of Gastroenterology and Hepatology.
Our previous liver conferences have been recognized as a comprehensive source for clinically diagnostic and treatment information in the southeast for Gastroenterologists and Internal/Family Medicine physicians. The 2016 conference will again draw gastroenterologists, internal medicine/ family medicine physicians and nurses from Alabama, Georgia, Florida, Tennessee, Mississippi and Louisiana who are concerned with the diagnosis and management of patients with gastrointestinal and liver disease. Presenters will include both UAB faculty and guest faculty of nationally acclaimed experts. Topics this year include: Barrett's esophagus, GERD, eosinophilic esophagitis, celiac disease, pancreatitis, difficult diarrhea, inflammatory bowel disease, GI issues in pregnancy, endoscopy in anticoagulated patients, liver transplantation, genetic liver disease, liver disease in pregnancy, hepatocellular carcinoma, cirrhosis, fatty liver disease, and hepatitis B & C
By partnering with us you will provide an invaluable educational experience while giving your company an opportunity to interact with key physician groups.
Please contact Sheri McFall at 205-975-9698 to discuss your participation in our conference. Exhibitor deadline is August 24, 2015. We are very excited about this upcoming course and we look forward to hearing from you soon!
Fred Weber, MD
Clinical Professor of Medicine
2016 Co-Director
Omar Massoud, MD
Associate Professor of Medicine
2016 Co-Director


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OAKLAND, Calif. — The third game of a four-game series between the Texas Rangers and Oakland A's features RHP Colby Lewis vs. RHP Bartolo Colon at 9:07 p.m. on ESPN Dallas 103.3 FM and FSSW. A quick look at the matchup:
Lewis (4-4, 3.50): The 32-year-old gave up just two earned runs in 6 2/3 innings in his last start on June 1, but he gave up two unearned runs and took a loss to the Los Angeles Angels. … After going 3-1 with a 1.93 ERA in April, Lewis has mixed good starts with bad ones since then, going 1-4 with a 4.81 ERA. … Went 4-0 with a 3.05 ERA against the A's last season … Has held right-handed batters to a .217 average and .240 on-base percentage this season, while lefties have hit .281 with a .326 OBP.
Colon (4-6, 4.34): The 39-year-old former Cy Young winner is in the second year of his "second career" after he missed 2010 while recovering from a shoulder injury. …. Went 3-2 with a 2.53 ERA in his first six starts and then 1-4 with a 6.75 in his past six starts. … Gave up two runs in seven innings in a 2-0 loss to the Royals in his previous start. … Is 12-1 with a 3.24 ERA in his career against the Rangers. … His victory total against Texas is the highest against any team.
Hitters: A's 2B Jemile Weeks is 7-for-12 against Lewis. … C Kurt Suzuki is just 4-for-23 against Lewis, but he has two homers. … 3B Adrian Beltre is 17-for-51 (.333) with four homers against Colon. … DH Michael Young is 15-for-42 (.357) against Colon.
Up Next:
Thur. at Oak.: RHP Yu Darvish(7-3, 3.21) vs. RHP Brandon McCarthy(4-3, 2.95), 2:37 p.m., ESPN Dallas 103.3 FM/1540 AM/FSSW
Fri. at S.F.: LHP Matt Harrison (703, 4.37) vs. LHP Barry Zito (5-2, 2.98), 8:15 p.m., ESPN Dallas 103.3 FM/1540 AM/TXA-21
Sat. at S.F.: RHP Scott Feldman (0-4, 7.01) vs. RHP Ryan Vogelsong (4-2, 2.38), 3:05 p.m., ESPN Dallas 103.3 FM/1540 AM/FSSW


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Although Looking Like It Was A New Time, I See Tenebrose, & Only Truth Awakens Lygophilia...& Kainotophobia. Although Never Drawn Before, Eternally Fighting, & Ritually Intertwined, Even Nearing Devistation... Seity Worn Hastily, Yet Inturn Sadly I Try, Seriousness Overruns Happieness, And Reality Dies.
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Winning, losing, mediocrity. That's the NBA pecking order these days, with those non-winning, non-tanking tweeners stuck in basketball limbo. Because, really, every GM's worst fear is to become the next Atlanta Hawks. Only Rockets GM Daryl Morey has tried to rebuild without blowing up the foundation, but the Rockets have stared straight into the eyes of mediocrity and seen nothing. There's nothing in that abyss for NBA teams, no light at the end of the tunnel. It's almost a rite of passage these days, sacrificing the mirage of present triumph for a would-be dynasty down the road in some not-so-near future. And while it might be a bit rough on the chew for fans of the supplicating team, it's necessary karmic justice.
But then there are the teams who cling to the present, tinkering with their roster and plodding through the waves of self-evident truth, that maybe starting over is the best course of action. These teams have moved all of their proverbial poker chips into the middle of the table and shown hands of various terror-inducing levels. They have to win now, if only to satiate the backwards ends-justifies-the-means logic or simply because non-winning equals non-losing as well, which only leaves mediocrity, our worst enemy. With that, here are five NBA teams in need of a championship right now, with anything less than hoisting the Larry O'Brien trophy a failure.
5. San Antonio Spurs
The ebb and flow of the NBA was never better personified by this year's San Antonio Spurs. For the second straight season they earned the Western Conference's No. 1 seed, advancing to the Western Conference Finals and grabbing a 2-0 lead over Oklahoma City. We pronounced them kings, reveled in their team-style play and their propensity for giving us some nasty. We even foolishly posited that they could and would steamroll Miami and that non-clutch, hairline-receding chump in that No. 6 jersey. But all of that disappeared rather quickly as OKC took flight and did younger and more athletic things, leaving the old and crusty Spurs in the dust.
It might be a stretch to say the Spurs need to win now, per se, if only because they've done a lot of winning previously. And although they've have their fair share of young, subsidiary parts filling in the gaps, Tony Parker, Manu Ginobili and Tim Duncan aren't getting any younger. If the last two years have been any indication, the Spurs can win now. But if your core three players are all over 30 years old, "can" slowly morphs into "must."
4. Miami Heat
LeBron James earned his first championship ring this past season, and that's all good and well. But you don't convene the super friends for just one NBA title. The Eastern Conference as a whole is essentially a doormat. Indiana couldn't even handle a handicapped Miami, Chicago with a healthy Derrick Rose lost to the Heat in five games, and the Boston Celtics just can't beat Miami when it counts. Even with Rajon Rondo's superhuman wheeling and dealing, the Celts fell short of matching LeBron's masterful bravado and withered away on the big stage.
But the real pressure stems from Dwyane Wade – or, really, non-Dwyane Wade, as he's proven to be of late. Injuries have riddled an otherwise stellar career, and his 30+ years are creaking and cracking a bit too much. And it's not like Wade has any legitimate trade value, since no NBA team would sacrifice the requisite parts to acquire a broken down once-superstar, and the Miami Heat would obliterate any lasting sense of basketball fealty by dealing the city's most cherished athletic star. LeBron James is chasing history now, and only his teammates really stand in the way. So while they're young, while they're (relatively) injury free, it's championship or endless Skip Bayless blathering.
3. Boston Celtics
Maybe Boston's accelerated ascent followed by its painstaking rise to the almost-top was the right formula after all. We sing their praises and applaud their sage-like saavy, as Rajon Rondo sautees and steams the ingredients into a masterful recipe for near-success. They only won once, in their first year, and placated our very high preseason expectations. Everything since then has been the cherry on top of the cherry, a glass half full kind of thing. Well, it's been four seasons of non-championships for the Celtics, but Danny Ainge still clings to the hope that one more ring is just around the corner – you don't sign an aging Jason Terry in a youth movement. Maybe it is or maybe it isn't, but Paul Pierce has already conceded a desire to test free agency when his contract runs out, and Kevin Garnett is on his last contract after nearly retiring in this very offseason.
Boston had its cake, except now they want to eat it too. More power to them, I say, but we're no longer in the territory of "if." Championship or not, Boston will demolish their roster's current structure in two years' time, so their championship window is not only now, but it's stringently capped at 730 days.
2. New York Knicks
James Dolan hoped to copy Boston's tri-wizard formula, except the summer of 2010 left New York with a partially broken wand and a bunch of how-to wizarding books. Eventually he swapped these tools for the future for another able-bodied magician, completing two thirds of the plan. But that third piece never found its way into a Knicks' uniform, instead evolving into Tyson Chandler and Jeremy Lin. That was fine and dandy, and, as J.R. Smith notes, they still look really good to win it all, sans Lin. Eight playoff losses and one playoff victory later, the Knicks are really under the gun now. In 2014-2015, the Knicks have $62 million committed to three players, which puts them over the current cap. We can expect it to rise a bit by then, but you don't hamstring future cap flexibility if you don't think you can get rings right now. Even if this type of thinking is hardly logical, the dollars speak loud and clear. The only way to salvage this salary cap disaster is NBA Finals victories. Now they've got to just, you know, do it.
1. Los Angeles Lakers
Kobe Bryant is a shell of his former self and isn't getting any younger. Andrew Bynum will be an unrestricted free agent come next season, and those max dollars will surely send him packing to another team. Pau Gasol is pretty good, and so is Steve Nash, but those two plus Kobe don't exactly equal a championship. So really, the Lakers' pressure doesn't even come from the fans, the media, or other third party sources. Without Andrew Bynum, this team will get eaten alive in the Western Conference. And, for those of you scoring at home, that gives the Lakers exactly one season to win the title. Of course, Pau Gasol could be traded and Andrew Bynum re-signed. In an ideal world, that is exactly what would happen. But that would take away from the 2012-2013 team, because the Lakers would likely take back expirings and picks as opposed to present assets.
That brings us back full circle, which is championship or bust. The Lakers are beyond all-in at this point, and it's been two years since the Lakers were championship relevant. Sure, they've parlayed a talented roster into a playoff fixture, but little else. Dallas and Oklahoma City have wiped the floor with their rotting carcass in two consecutive years, and that's no good. Now, will they win the title this coming season? Eh, who knows. There's a lot of quality teams out there, especially in the West, so that remains to be seen. But if they don't win, you can expect Kobe to punch Pau Gasol in the face – that rage has been building for years now.
Which NBA team is under the most pressure to win a title now?
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Showing Results: Most Recent
This review is from: EVGA 04G-P4-3688-KR GeForce GTX 680 Classified 4GB 256-bit GDDR5 PCI Express 3.0 x16 HDCP Ready SLI Support Video Card
Pros: This card can handle any game thrown at it at 1920x1080. Have played Crysis 1 2 & 3, Fallout 3 & New Vegas, Battlefield 3, Defiance, Deadspace 1 2 & 3, Skyrim heavily modded, Metro 2033 & Last light, Dragonage 1 & 2, Guildwars 2, Aliens vs Predator, the Old Republic Online, Resident evil 5 6 & revelations, dishonored, Bioshock all of them, Boarderlands 1 & 2 and Shadow Runner Returns. All with vsync on to prevent screen tearing.
As for temps first card in a long time I can leave auto fan on and not go over 60c not to mention the card runs almost silent.
Cons: I didn't get from newegg but cannot beat the deal I got on amz for $350
Other Thoughts: Running this PC with
Core I7 970
Intel DX58OG
Ripjaws X Series 48GB DDR3 1333
Vengeance Series C70 Military Green case
SuperNOVA NEX750G
2x WD6000HLHX 600GB
1TB Samsung 7200
120GB GSkill Phoenix SSD
This review is from: Cooler Master Seidon 120M - All-In-One CPU Liquid Water Cooling System with 120mm Radiator and Fan
Pros: Size, looks good in a case, does what it should when it works...
Cons: Pump is really cheap, will not even send a signal to motherboard if it has failed/is failing, PC was having hard locks the lights would go out on my mouse. So figured it was a firmware issue on my mouse then in the middle of a firmware update wham computer locked up and my razer old republic mouse bricked, got a death adder from Wally World. Was gaming and kept locking up, then just in windows same thing same symptoms as before . Then not even windows was stable I heard a loud grinding then a large pop. It was 100% dead. Lost money on hardware it took out, really a huge disappointment nor will I buy an over priced cooler master anything agai. So buyer beware keep away from this and or any other cm product
Other Thoughts: Stay awayREAD FULL REVIEW
This review is from: Corsair Vengeance Series C70 Military Green Steel ATX Mid Tower Computer Case
Pros: Lots of room for anything! Have a corsair h50 unit, and an Artic cooling Accellero hybrid gpu cooler both in the top of the case. Sturdy, very well built & designed. Handles on the top are great when you need to move your PC. The easy latch system for the side panels makes getting to anything in your case easy & painless. Just an all out great case. Was looking at this and the hafx, cooler masters case does not hold a candle next to this one.
Cons: On other side of motherboard tray the plastic latches are a little flimsy. They break easily take your time. If you plan in liquid cooling be it a simple closed system or more traditional and you plan on having push pull fans on the radiators make sure board & ram are installed first. Along with the MOSFET cooler some boards have at the top if its too large you may want to get some small low profile passive copper heat sinks to keep the MOSFET chips cool and not keeping you from installing the second fan on the radiator.
Other Thoughts: Didn't get it on the egg was cheaper to get locally.READ FULL REVIEW


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Craig Gibsone & Vera Franco
11 February - 10 March 2017
Co-creating a Regenerative CultureHow do we live in a way that is fulfilling and respectful to ourselves and all life around us? With all the changes, paradoxes, and challenges of our times, where do you and I, as individuals, come in, create change and contribute to re-imagining the future?
Join us in February 2017 for the 18th year of the Findhorn Foundation's most complete and holistic ecovillage course. Together we will consider personal and systemic solutions that help us address the complex situations we are facing in our society in a creative, nourishing and sustainable way.
Taking a holistic approach, the course takes an in-depth look at a wide range of topics: social and ecological regeneration, economy and energy systems, governance and decision-making, nature, our inner nature, and much more.
Whether ecological design, permaculture, systemic biomimicry, or regenerative design, all these approaches share a design-based methodology that applies life's operating instructions and ecosocial literacy to co-creating a future where humanity and all of life can thrive. We are the Re-Generation! If not us, then who? If not now, then when?
We will equip ourselves with the skills needed to create a diverse and re-generative culture that connects humans with nature, all life and ourselves. A culture in which we see each other as part of the bountiful and generous natural ecosystem that is the livelihood of every living being. A culture which gives us a greater feeling of belonging to the Earth and the Earth belonging to us.
The course has helped me discover and connect with my own deep truth and honesty, given me space and tools to express it and inspired motivation and courage to act on it.
More information
More about the Applied Ecovillage Living course:
Inspiration for this pioneering month-long course came during the creation of the Global Ecovillage Network and was promptly recognised by UNITAR (United Nations Institute for Training and Research) in 1998. It contributed greatly to the formation of Gaia Education and the curriculum of its most successful international educational programme, Ecovillage Design Education.
Intentional ecological communities, ecovillages, are cohesive social structures, united by common values. They aim to restore the balance between the four elements: earth, air, fire and water, returning humans to a sustainable relationship with all other communities of life. Working with the principle of not taking away from the Earth more than they give back, they are consciously diminishing their ecological footprint. The ecovillage model can be applied equally to urban and rural settings, in developing and developed countries.
You will Learn:
- Social tools for personal and group transformation, empowerment and community building
- Urban and rural solutions for transitioning to a resilient society
- Local organic food production and right livelihood
- Comprehensive Permaculture design introduction
- Renewable energy systems and energy efficiency models
- Cooperative social economies and complementary currencies
- Holistic decision-making processes, including nature and deep ecology
- Earth restoration projects and biological waste water treatments
- Ecological building and community design
- Cultural and Spiritual diversity practices
Ecovillages aim to restore the balance between the four elements: earth, air, fire and water, returning humans to a sustainable relationship with all other communities of life. With practical tools and living group experience we will cultivate an embodied sense of self and place. This dynamic world work opens you to vision, inspiration and insight into your true purpose in life.
Living and Learning in Findhorn Foundation and Community
We will explore how ecovillages serve as models of environmental, social, economic and spiritual sustainability, meeting the increasingly urgent global need for viable, sustainable human settlements. Our base is the Findhorn Foundation community, a pioneering ecovillage dedicated to co-creation with spirit and nature. This course is an invitation to be part of the community's unique interwoven tapestry, participating and interacting with all the people who cook, clean, grow, eat, produce, explore, and learn there. You will experience firsthand how an ecovillage and community can provide an enhanced quality of life for all species and how it might reharmonise our relationship with the natural world in an empowering way.
We will use the many activities and businesses of the community/ecovillage as tangible examples of ways to live out sustainability and regeneration in practice. You will see various approaches to how sustainability projects can engage symbiotically with a wider geographical area to foster human and ecosystem resilience.
Within the space of this vibrant community, we will form our own group dynamic and support one another in integrating the rich and diverse content of this course. This is a safe and permeable environment created to value you for who you are and stimulate movement from theory to deep practice. The structure and practical work of the course will empower you with the inner and outer tools to create your own place in the world.
The AEL month in brief
During the first part of the course we explore models for urban approaches to the Ecovillage concept by setting up our living classroom at Cluny Hill, a former Victorian hotel now owned by the community and home for up to 120 residents. The building contributes greatly to the reduction of the community's carbon footprint and is also located in the town of Forres, part of the Transition Town network.
For the second part we move our living classroom to The Park, the original site where the Findhorn Community and Ecovillage was born. Here we broaden our enquiry in a more rural setting with smaller, dispersed dwellings, using as a case study the restorative process of transforming sand dunes on an old military base into the famous Findhorn gardens.
Week 1 - People Care:
Building Effective Groups, Deep Ecology & Designing For Transition
In this week we introduce ourselves and our projects to one another, co-creating the learning environment we need by building group respect and understanding as a basis for concerted action. Using deep ecology, we place ourselves within the web of life as a creative, accountable species and examine our impact upon the Earth. The embodied expertise in the community and the three permaculture ethics: people care, fair share and Earth care, guide us to our next steps in living a responsible future.
Week 2 - Fair Share:
Economic Sustainability, Right Livelihood & Organic Food Production
n this week we explore how we can live well on the Earth, providing for our needs in a way that respects our own community, communities in other parts of the world and the ecosystems that support and sustain us. We will visit small community farms, studying their production methods, exploring their values and digging more deeply into underlying concepts such as right livelihood and voluntary simplicity that are needed to walk more gently on the Earth. The Findhorn Foundation community provides us with tools and examples, including a large and diverse organic food production network, a community bank and currency, and a range of other social enterprises.
Week 3 – Earth Care:
Human Settlements, Ecological Building & Wilderness Restoration
In this week we explore the design and construction of ecological settlements that fit harmlessly into the landscape and into different climatic regions, engage in hands-on learning about our biological waste water treatment and a diverse range of renewable energy systems, explore the Scottish wilderness and support the restoration and protection of our wild frontiers.
Week 4 – Next Steps Design:
The Principles of Permaculture & Designing for the Future
With celebration and ritual, the final week weaves together the various threads we spin during the first three weeks, grounding the experience and preparing our onward steps. Working on projects in groups and drawing on the human, physical and spiritual resources of the Findhorn Ecovillage, we create practical designs for new initiatives that can be implemented in your home environment. Integrating and harmonising our human footprint starts at home.
Week 5 (optional) – Grounding and Integrating
After the end of the course, there is an optional fifth week to further integrate the experiences of this intensive month. It is an offering to those who wish to immerse themselves more fully in the Findhorn community, with time for deepening practical knowledge and having more space to feel into and plan next steps. The week has no set schedule other than the daily rhythms of the community, but there will be plenty of opportunities for completing projects, gardening, beach walks, sharing, and eating together. This week does not need to be booked in advance.
You can view a draft schedule for the month here.
Testimonials from the AEL 2016
AEL 2016 fun group photo. We had 17 participants from nine different countries, aged between 18 and 73.
It has helped me know what I want from community. And it was very helpful and inspiring to be with others sharing the same values. And it has been a very useful way for me to experience Findhorn.
AEL reveals how far removed our culture is from the richness and diversity of nature.
Thank you for this opportunity to learn, grow, dream, refocus and heal.
Exploring the self in relation to the world, exploring the world in relation to yourself. Magical mystery tour :) It was really helpful and I am thankful, also for the honesty and transparency of the focalisers and of the place itself.
It helped me to cultivate my discernment (my process) alongside an (outer world) focus. Best educational experience I've ever had in my life. It is truly transformative.
Overall I thought it was great, I really liked the combination of education/information sharing, group work and applied experience. It was very helpful in exposure to a wide range of thoughts, emotions and experiences.
I loved it, it is a course that more than a course it feels like a journey into the being, the self, life and the current situation of the world. The change starts from within, it is a statement often used and rarely experienced, this journey applies it 100%. I connected with myself and understood that the change truly comes from within.
This month was a very powerful and exciting experience because of the passion and knowledge and I am sure it changed my coming life in a positive way.
Our Team
Craig Gibsone and Vera Franco are currently responsible for organising and holding the overall learning journey of the AEL.
Craig Gibsone is a feral elder of the community and artist, and is one of the creators of this pioneering programme. He lives permaculture and has created a little paradise in Findhorn where his whiskey barrel house and garden inspire all those who wander there.
Vera Franco is a young educator and an alumnus of the AEL. She is passionate about spirituality and connection with nature, education as a holistic journey of empowerment of the learner through creativity, and is a firm believer in human spirit and potential.
We also bring a wide team of experts and educators, inventors and inspiring people to express the vibrant diversity of our community and the richness of life.
May East is a sustainability practitioner, educator and designer and has a diploma in Climate Change Diplomacy and an MSc in Spatial Planning. Based at the UN Habitat Best Practice Designation Findhorn Ecovillage since 1992, she has been leading a whole generation of sustainability educators delivering capacity building activities in 41 countries in many different stages of development and in both urban and rural contexts. Recognised as one of 100 Global SustainAbility Leaders three years in a row, she currently serves as Gaia Education Chief Executive and a UNITAR Fellow. An accomplished facilitator of international think-tanks, roundtables and training programmes, May is an inspirational teacher for many. With cross-cultural experience in both Global North and South, she specialises in working with intergovernmental agencies, educational institutions and the United Nations in the creation of policy guidelines for sustainable development.
Alan Watson Featherstone founded the award-winning charity Trees for Life in 1989, and has been its Executive Director since then, with overall responsibility for the charity and its strategic direction. His work includes a special focus on media and public relations, major donor fundraising and biodiversity research at their Dundreggan Conservation Estate.
Alex Walker has lived in the Findhorn Community for more than 25 years during which time he has been a sustainability consultant and a social entrepreneur in a variety of fields both in Findhorn and elsewhere. He has lectured widely on the prospects for a low carbon economy. He is currently a director of Findhorn Wind Park, and chairman of Ekopia Ltd, which operates the local Eko currency and supports numerous local social enterprises, including those providing affordable housing. He is also a board member of Development Trusts Association Scotland.
Eveline Rodenburg is a herbalist, functional nutritionist and gardener. She helps people choose a healthier life style and makes herbal remedies for the community using plants growing in The Park and surrounds. Eveline's website.
Graham Meltzer PhD has a deep, abiding passion for shared or communal living, having lived two years on Kibbutz, eight years in Australia's largest commune and 11 years at Findhorn. In Australia he worked as an architect, academic and photographer. His doctoral research focused on cohousing - looking specifically at the link between social cohesion and effective environmentalism. Graham currently organises conferences in the Findhorn Foundation, teaches eco-architecture in the Findhorn Foundation College and has recently moved back into designing and developing buildings and infrastructure for the Foundation and the Park Ecovillage.
Mathis Rosenbusch is a food grower with 10 years' experience in bio-dynamic farming in Germany. In 1994 he founded Earthshare, the first Scottish Community Supported Agriculture Scheme (CSA), near Findhorn. In 2004 he founded La Jimena in Spain, a supplementary CSA scheme cooperating with various other schemes Europe-wide, seeking a CSA way of supplying the 'Mediterranean aspect' of food. His specialty topics are biodynamics, CSA and sustainability.
Maria Cooper, born in Scotland but raised in Sweden, has always been close to nature. During her university years she discovered the Transition Movement and became very involved in a local group, in particular community gardens, local currencies, deep ecology and behaviour change projects. She is now involved in the Transition Network, looking at how we can use permaculture design to reinvent local communities and social relationships, especially on the edge between conventional academic education and sustainable living. She is currently living in Findhorn and, when Maria is not lost in her garden, she works for the Global Ecovillage Network, as well as on sustainable refugee projects.
Jason (Jay) Caddy, is a director of local ecological construction company Green Leaf Design & Build. From idea to completion Jay has a strong grasp of the process of delivering ecological structures into the world. Using local foraged ingredients for brewing medicinal beverages that sooth the soul and enliven the senses is also one of his passions.
Javier Rodriguez, M.A. Clinical Psychology, trained for four years as a Gestalt Therapist, a year in Cognitive Behaviour therapy, and has different in-depth trainings in Process Work, Non Violent Communication, the Transformation Game, Frameworks Coaching process, and different tools related to spiritual and personal growth. He has been working locally for 15 years as a therapist, mentor and coach supporting people in times of transition, crisis and change. For four years he was with the Foundation's Spiritual and Personal Development department responsible for the Foundation Year Programme, and mentoring and coaching potential staff members.
Britta Schmitz PhD has been with the Foundation for the past eight years, five of which were living and working at the Foundation's satellite community on the tiny Isle of Erraid before moving to the Park where she currently co-focalises Cullerne Garden. Her passion is community life and the focus of her work is 'People Care'. Her spiritual path has taken her on a shamanic journey and she is a firewalking instructor and moondancer. Prior to living on Erraid she worked at university. Her research for her PhD focussed on how men develop gender identity in our challenging times.
Credentials and Certification
The Applied Ecovillage Living now has a Gaia Education certified Ecovillage Design Education Curriculum, is currently recognised by UNESCO, and a contributor to the Global Action Programme on Education for Sustainable Development.
Learn more about Gaia Education here and about UNESCO's Global Action Programme on Education for Sustainable Development here.
Findhorn Ecovillage is an ever-evolving, living demonstration of creative solutions for the future.
- The largest single intentional community in the UK
- Linking spiritual, social, ecological and economic domains
- A pioneering ecovillage since 1985, receiving Best Practice designation from the United Nations Centre for Human Settlements (Habitat)
- A major centre for holistic learning serving 9,000 visitors a year from over 50 countries
The Findhorn Foundation has one of the lowest recorded ecological footprints for any community in the industrialised world, just half the UK national average, and has birthed more than 50 businesses and social ventures in the local region.
- Over 60 ecologically benign buildings
- Three wind turbines with a total capacity of 675 kW
- A biological Living Machine sewage treatment system
- Numerous solar water heating systems
- Biomass boiler heating system total capacity of 250 kW
- Comprehensive recycling and composting scheme
- Published UK's first technical guide to ecological housing
- Our own community currency and community investment fund
- Is served by a car-sharing club that includes zero-emissions electric vehicles
50+ Years of Embodied Knowledge and Wisdom:
The Findhorn Foundation participates in the United Nations as a Non-Governmental Organisation, actively sharing our knowledge and experience of integrated and sustainable development.
Tiered price (click here for more information): £2440 / £2010 / £1840
Tiered Pricing
Before you book your place, please take a moment to consider that the Findhorn Foundation is a Charitable Trust. We believe that the benefits of holistic learning should be available to everyone regardless of their financial or life situation, and that the transformational journey is enriched by a diversity of participants.
We recognise that what is affordable for some can be a financial stretch for others and offer a tiered pricing structure. When you book, please select the price that feels appropriate for you.
Pay it Forward Price covers the cost of your workshop and includes a contribution to our bursary fund. This will make participation possible for one or more people who otherwise would not be able to join our transformational work in the world.
Sustainable Price covers the cost of your workshop and helps us to sustain our learning and guest facilities.
Supported Price reflects a partial bursary toward the cost of your workshop and is intended for those with minor financial need.
Convert to your own currency using The Universal Currency Converter.
- If you cannot afford the full fee, you can apply for a bursary when completing the Application Form. A limited number of bursaries, funded by trusts and the Findhorn Foundation itself, are available to suitable applicants. Applications for financial assistance should be made as soon as possible. This will enable us to assess all applicants and allocate funds in the fairest possible manner.
- If you can afford to pay more than the full fee for this programme you can make a donation to the bursary fund when completing the Application Form. Your donation will be gratefully received and used to help those who cannot afford the whole fee.
For more information send an email to
Presented in association with
GEN Europe
Gaia Education


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"Save America's Treasures" has been totally eliminated—the largest Federal program supporting preservation of such treasures as the original Star Spangled Banner and George Washington's tent.
65% of Americans don't know what happened at the Constitutional Convention, according to a recent survey by Newsweek.
The "Teaching American History" grants—the largest Federal program supporting history education—have been completely eliminated.
Visits to the Top 20 Civil War battlefields have dropped in half from 1970 to 2009 according to official National Park Service statistics.
40% of Americans can't identify whom we fought in World War II, according to a recent survey by Newsweek.
A quarter of Americans believe Congress shares power over U.S. foreign policy with the United Nations, according to a recent Annenberg survey.
"There is little that is more important for an American citizen to know than the history and traditions of his country," John F. Kennedy wrote in American Heritage.
The "We the People Program," which touched some 30 million students and 90,000 teachers over 25 years, has been completely eliminated.
Two-thirds of Americans could not correctly name Yorktown as the last major military action of the American Revolution, according to a recent national Gallup survey.
The National Heritage Areas and Scenic Byways program, the only major Federal program encouraging visits to historic places, has been completely eliminated in Congressional committee.
A young man from Queens jumps into the thick of World War II intelligence activities by translating secret Japanese messages
IN HIS MARVELOUS MEMOIR, Flights of Passage, my friend and onetime colleague Samuel Hynes, a Marine Corps combat aviator in World War II, writes that the war is the shared secret of his generation—those young men who came of age between December 7, 1941, and September 2, 1945. For those of the approximately 12 million Americans in uniform for some or all of those years, it was an experience both personal and collective like nothing before or after. Those who went through the hell of combat carry physical and emotional scars as reminders.Read more »
The Women Airforce Service Pilots seemed strange and exotic to World War II America. In fact, not even the military could quite fiqure out what to do with them.
Curiosity, patriotism, and even a hint of scandal lured the residents of Sweetwater, Texas, to the outskirts of town one April morning in 1943. The townspeople made a day of it, setting out picnic lunches near the military training base at Avenger Field and searching the sky for incoming aircraft. "Cars lined old Highway 80 for two miles in each direction from the Main Gate," recalled 17-year-old Hershel Whittington. The first sightings came in mid-afternoon, and then dozens of planes, open cockpit and single propeller, began passing over the rolling plains of tumbleweed and cactus beyond town on the way to the base. "Here comes one," someone shouted. "And here's another!"
The world-shaping relationship between these two giants got off to a rocky start
Often it is said that vast long-range economic and social forces, not the efforts of leading individuals alone, make history. The course of World War II denies this seemingly rational thesis. Hitler began World War II; he and his principal adversaries—Britain's Winston Churchill, America's Franklin Roosevelt, and Russia's Joseph Stalin—determined the conflict's course and outcome. While the latter two effectively won the war in 1945, Churchill played a significant role by not losing it in 1940 and 1941.Read more »
Gene Wilder discusses his new World War I adventure
Gene Wilder, the son of russian Jewish immigrants, was born in Milwaukee in 1933.Read more »
You can go there too, even to the Bates Motel
Although Alfred Hitchcock lived in the United States for more than 40 years, becoming an American citizen in 1955, five years after his wife, Alma, he carefully retained his Britishness. Even in the warm sunshine of Southern California he always turned up for work in an immaculately tailored dark suit, and his wardrobe held dozens of them, all identical except for their varying waistbands.Read more »
Pork Barrel
A "Call it Pork or Necessity, but Alaska Comes Out Far Above the Rest in Spending." This headline—from The New York Times—was for a story about the $388 billion federal Consolidated Appropriations Act for 2005. "Consolidated" is an apt word for this annual exercise: The act is nearly 1,700 pages long or, looking at it another way, more than a foot thick. Buried within it are thousands of local projects for which funds have been specially set aside. In official congressional parlance, grants of this sort are called "earmarks." Most people call them pork .Read more »
"The founding of the United States experience: 1763-1815"
The book that taught GI's how to behave in England
There were three deadly serious crimes a serviceman could commit, said the United States Army Air Corps commander Carl ("Tooey") Spaatz; "Murder, rape, and interference with Anglo-American relations. The first two might conceivably be pardoned, but the third one, never." Seemingly Gen. Dwight D. Eisenhower agreed. When he learned that two different-nationality officers of his integrated staff had exchanged harsh words, he sent the American one home.
The Automobile License Plate Collectors Association is the world's largest club devoted to the hobby; members benefit from a bimonthly newsletter, an annual convention, and regional meets (ALPCA, Inc., 508 Coastal Drive, Virginia Beach, VA 23451; www.alpca.org ). Great plates abound on the Internet. Start at www.alpca.org, click on "Gallery" for select examples and on "Links" for the best hobbyist sites. Skip books that spotlight clever vanity plates, and opt instead for informative volumes. James K.Read more »
© Copyright 1949-2016 American Heritage Publishing. All Rights Reserved.


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post #1 of 1295 Old 09-09-2006, 10:17 AM Thread Starter
What are you listening to right now?
what was the last song you heard? mine is Panic! at the disco(i write sin not tragedies)
post #2 of 1295 Old 09-09-2006, 10:34 AM
post #3 of 1295 Old 09-09-2006, 02:35 PM
55 Gallon:1 Baby Bristlienose,1 Swordtail, 1 Bala Shark, 2 Common Pleco, 2 Clown Loaches, 2 angel fish,3 (look a like) rasbora Tetra's, 4 Black Skirt Tetra's, 4 Long-finned Gold Zebra Danios, 4 Cardinal Jumbo Tetra's,6 Red Eye Tetra's, 7 neon tetra's
10 Gallon Nano Reef:1 Chocolate Starfish, many snails...Work is in progress...err
post #4 of 1295 Old 09-09-2006, 04:38 PM
Stand by me
when you set up a new tank,hide an extra
sponge or two behind some decor,that way you have
something seeded for you next filter.
post #5 of 1295 Old 09-09-2006, 06:57 PM
post #6 of 1295 Old 09-09-2006, 07:56 PM
post #7 of 1295 Old 09-09-2006, 07:56 PM
High School Musical-Start of Something New
Sent from my desktop or phone or whatever else I am holding on to
I'm ready for the pressure.
The drama and the pleasure!
If there is one thing I want to see here, it's HUMOR.
I believe I can fly!
I believe I can touch the sky!
I think about it every night and day!
I stand in awe of my body.
post #8 of 1295 Old 09-09-2006, 07:58 PM Thread Starter
post #9 of 1295 Old 09-10-2006, 02:14 AM
Flawed Design (Stabilo)
You know what the definition of hobby is: something of interest that is going to cost you lots of money!
post #10 of 1295 Old 09-10-2006, 02:46 PM Thread Starter
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Hotfrog Philippines provides information regarding Asialink Finance in Pasig Metro Manila. Asialink Finance is located at 2/F, AIC Gold Tower, Emerald Avenue, Pasig Metro Manila and provides Financial services. Contact them on (02) 635 6638.
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Web design modification
- Status Completed
- Budget N/A
- Total Bids 27
Project Description
I will shortly have OpenGTS vehicle tracking installed in a VPS. I need help with creating a website for our company that looks professional and has
Home ...About us Solution ...Product... ...Dealers.. ...Contact.. Track Login
Please provide proposals.
The "Track Login" link to my tracker which is something like this. [url removed, login to view]
I also need customization help on the login page of Open GTS. It should be simple but different from how it looks as default.
This is for short term however in a year or so will change it to a full blown commercial website. So whoever bids is highly likely to be hired again or get into long term arrangement for continuous upgrade and improvement.
All build and development will be first tested into test server then will be moved to production server. All severs are Linux CentOS based.Get free quotes for a project like this
Completed by:
Skills Required
Looking to make some money?
- Set your budget and the timeframe
- Outline your proposal
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Hire Freelancers who also bid on this project
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text: This quirky but quaint little restaurant is a must try if you're visiting Nashville, Indiana. Our family has been patrons over the last 20+ years and couldn't imagine popping in and having a bite to eat and saying hello to Larry. Definitely try breakfast because you cannot go wrong and anything on the lunch menu is outstanding.


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The Dark Warrior
I am the Dark Warrior.
My story is not one that will cause you to like me. I don't live for approval. At least not from you. I do what I do because my people depend on me for survival and if that offends you then that is not my problem.
My gift is that of leadership. Some say I am ambitious. They mistake what I do as a need for personal glory.
The truth is….I am ambitious. But I am not here for personal glory. I serve the All Father.
I was sent here to this realm, to these people for a purpose.
I have died and been reborn countless times. I slip from eternity to eternity from realm to realm. As do we all. My journey was decided for me long ago. Because I have this knowledge I am not afraid to make choices and decisions that may be viewed as unpopular by those who don't yet understand that they have a purpose, let alone what that purpose might be. It's okay though, they will find awareness. In this life…or the next…or even the next.
This musing was inspired by the song If I Had a Heart by Fever Ray
As I listened to this song and just began to write, as I intend to do with all of my musical musings, this story piece just began to flow. It's crude, but its a start on my journey to burn this writer's block to the ground!
The Right to Write
Goddamn Writer's Block! This shit has been plaguing me for months and months! I cannot tell you how many times I've sat down to this blog and come up with….Fuck All.
But, I suppose that's why I have this space. So I can write whatever pops into my head and you can read it if you feel like it.
So, I had an idea. Music blogging. Not blogging about songs, but blogging about whatever the song evokes in me in the moment.
This could be a very psycho journey, but what the fuck? Let's do it! And, don't worry, I'll make sure to link it so if you listen to it you can also buy it easily because if you're like me, you'll obsess and obsess over some songs and have to know everything about it and empty your wallet into iTunes to have it. I spend waaaayyyyy too fucking much money on things like iTunes and Audible. Good God Audible. Best idea EVER. I'll hook you up there too.
Do you ever obsess over songs? Like, you hear a song and you have to listen to it over and over? Well, it's one of my more…bizzarre…habits. Songs, shows, books….You name it. Obsess!!! But whatever, Snow need topic so Snow can get her writing pants back on. Snow write about media.
Enter The Family
I suppose before I really get crackin' on this blog, I should probably hurry up and make some really random weird names up to protect my family's anonymity.
Ummm….Let's see:
Alias: Chef … because he's a chef. You can pretty much plan on the rest of these aliases being as clever as this one.
Child number 1:
Alias: 10 Kid, The 10 Year Old.
Child number 2:
Alias: 9 Kid, The 9 Year Old
The Dog:
Alias: Dog, Old Bat, Bag of Bones, Old Lady, Mamma
What?!? She's 16!! In dog years that's in the neighborhood of ninety some 'odd…she's earned a few fucking nick names from this nick name slinging family over the years.
Okay, I think that's enough. If I end up writing about the same people over and over, I'll come back here and add them for easy reference.
Fresh starts
with Comments closed | ∞
Fresh starts are a great thing. Don't you think?
I am a big fan of fresh starts and that is exactly what I am doing. I am so sick of blogging for bucks, blogging for someone else, blogging for SEO. Fuck it. I'm done. No deadlines. No specified topics. It just sucks the joy out of it when there are strings attached and I love to blog! It is a joy for me. But it wasn't for a long time.
When there is pressure attached, all the good stuff goes out the window of my brain anyway.
I'm just going to sit here. Anonymously banging away at this keyboard, doing what I like and not really giving a shit who is or isn't reading this.
This is my play ground and if you don't like it I invite you to enjoy this fine video:
Later Gator


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I could not have written my book "Evidence of Harm" without Vaccination News - the most thorough online compendium of real-time news and analysis from around the world. Whatever your views on vaccination are, this is a vital and useful site.
This is an awful not for profit. Please do not give money to this group! You would be far better donating money to immunology research so that vaccinations can be improved. This website is unscientific and makes false claims that it is providing fair and balanced information when it is clearly picking and choosing information that suits it agenda. Please stop spreading such dangerous lies. Vaccinations are important, and have done a lot for the health of humanity in general. The worst non profit group I have ever come across!
An very informative website that I have referenced for years. Thanks to vaccinationnews.org and Sandy for all that you do.
I could not have written my book "Evidence of Harm" without Vaccination News - the most thorough online compendium of real-time news and analysis from around the world. Whatever your views on vaccination are, this is a vital and useful site.
Previous Stories
I am an author, journalist and blogger (Huffington Post, Take Part, etc) who has written about vaccine safety issues for 10 years. During that entire time, there has never been a more comprehensive site covering vaccine news stories of the day than this one. It makes my work go so much more efficiently.
This is an indespensible website not only for keeping up with the latest news, it has an irreplaceable archive.
Previous Stories
I have known Sandy Gottstein for 14 years. She has dedicated many years speaking out for the vaccine injured, helping many along the way with her time, talent, and treasure. Vaccination News has helped millions of people become informed on the both sides of the vaccine issue. She has battled for our rights, and our children's rights. Thank you Sandy for all of the long hours of work you have put into the vaccine issue, and for the wonderful resource Vaccination News. You truly are among those who paved the path from the beginning.
Previous Stories
I first became aware of the vaccination issue when both my sons had adverse events from vaccines. I decided to do some research, and was fortunate enough to meet Sandy Gottstein President of VN. The information on the website is all-encompassing, which enables readers to see both the pros and cons of the issue.
The news which is posted daily on the website keeps you up to date on all the breaking news on the subject. Much of the news articles posted will not be easily accessible through mainstream media.
Vaccination News helps countless numbers of people from around the world understand this issue. It has helped parents, journalists and medical professionals find the information they need to help their children, write books and journal articles.
The archives are extensive and include articles that can no longer be found elsewhere.
Sandy's blog is great: her information about vaccines is detailed and accurate, and has helped me learn the facts on many occasions, which I'm then able to use in my comments on the Web. I'm grateful to her for having done so much work to serve the public interest.
Vaccination News is a very valuable resource - an archive and library of all news and views of the vaccination debate for well over a decade. The website is unique in that worldwide news from all sides of the debate are presented. President Sandy Gottstein's timeless, fully referenced and highly regarded columns are also housed on the Vaccination News website, as well as numerous other columns by medical professionals and others. No matter what the hot news of the day is, be it the recent CDC Whistleblower revelations or some other hot vaccine story, visiting the Vaccination News site daily allows me to see pertinent news reports and blog posts in one place. Invaluable!
Previous Stories
Vaccination has been called the "Issue of Our Times" by Mothering Magazine Editor Peggy O'Mara. The reason I value Vaccination News is that you can view/read/search for all viewpoints on the vaccine issue. Unlike any other website, Vaccination News provides a daily snapshot of vaccine news and views going back to 2002 on a searchable database. Founder Sandy Gottstein's and her contributor's columns are well researched, referenced, timeless investigations of vaccine issues. Vaccination News is an incredible history, archive, and a great asset to parents and the public.
Sandy is really committed to the cause.
It is strange how such dedication only seems possible outside the world of politics.
Yet, politicians have a 50% chance of becoming a millionaire through their commitments... although it is always difficult to know what those commitments really are and we never seem to reach a conclusion.
Today we seem to have an even greater disconnect between We the People and those elected to Represent us. Vaccination is a notable example.
Previous Stories
I would like to commend Sandy Gottstein for sticking to her guns in spite of the personal costs, both in time and money, that is required.
After all, the Big Guns won't sponsor information that reduces their market.
Her supporters are mostly wise after the event and struggling with a child that has been harmed, ostensibly by vaccines but they are usually told that the cause must lie elsewhere (and the related medical costs not to mention social and psychological burdens). This limits the time and donations they are able to donate.
Indeed, why aren't government health agencies and politicians carrying this fight? That is their sworn duty and elected purpose.
Cynically, grants and contributions mean more to them.
Hopefully, being voted out of office will prove the greater evil than forsaking some grants and contributions.
Above all, women voters never forget and impaired children can never vote.
Finding Resources you can TRUST is always a challenge. Vaccination News has emerged to be one of the best. Vaccines stimulate a huge number of articles, blogs, opinions, rage and oftentimes flat out misinformation. Being able to have a resource that helps you find the valuable studies and emerging data is priceless! Keep up the GREAT Work!!!
Over the years, I have found Vaccination News to be an incredible resource for well-balanced and honest information on vaccines.


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The Data and Safety Monitoring Plan, adopted by the H. Lee Moffitt Cancer Center and Research Institute originally in 2002 and revised repeatedly throughout the grant period, ensures that all clinical research conducted or coordinated by the Cancer Center is scientifically well designed, responsibly managed, appropriately reported, and that it protects the rights and welfare of human participants. The institutional plan conforms to NIH and NCI policies and guidelines regarding data and safety monitoring. The methodology and amount of monitoring required are dictated by the degree of risk involved to the individual patients and the complexity of the clinical research. Because the specific types of monitoring and reporting needed vary by the nature of the individual trial, the responsibility for ensuring that monitoring is appropriate, timely, and effective encompasses a number of Cancer Center individuals and groups. The Associate Center Director for Clinical Investigations has overall responsibility for data and safety monitoring, and the Protocol Monitoring Committee (PMC) is the Institution's venue for review of all monitoring reports. The PMC has a separate and distinct function from the Scientific Review Committee and the IRB. Its primary tasks are to: ? Assess safety by reviewing severe adverse event reports from investigator-initiated studies and monitor their timely and appropriate reports to oversight agencies (such as the IRB, FDA, or NCI). ? Review audits of investigator-initiated clinical trials ? Review interim data and safety reports from investigator-initiated studies ? Review the interim and final reports from the external Data Safety and Monitoring Board The Protocol Monitoring Committee (PMC), chaired by Scott Antonia, MD, PhD, includes members from a variety of the Cancer Center's clinical and scientific programs who have extensive experience with clinical research. The DSM requests CCSG Support of $72,617 for support of Protocol Monitoring Committee activities.
Data and Safety Monitoring at Moffitt provides a level of monitoring during clinical trials that is necessary to protect the safety of human subjects and to ensure the validity and scientific integrity of clinical trial data.
|Chung, Brile; Stuge, Tor B; Murad, John P et al. (2014) Antigen-specific inhibition of high-avidity T cell target lysis by low-avidity T cells via trogocytosis. Cell Rep 8:871-82
|Charbonneau, Bridget; Block, Matthew S; Bamlet, William R et al. (2014) Risk of ovarian cancer and the NF-*B pathway: genetic association with IL1A and TNFSF10. Cancer Res 74:852-61
|Unrod, Marina; Simmons, Vani N; Sutton, Steven K et al. (2014) A randomized clinical trial of self-help intervention for smoking cessation: research design, interventions, and baseline data. Contemp Clin Trials 38:284-90
|Osorio, Ana; Milne, Roger L; Kuchenbaecker, Karoline et al. (2014) DNA glycosylases involved in base excision repair may be associated with cancer risk in BRCA1 and BRCA2 mutation carriers. PLoS Genet 10:e1004256
|Padron, Eric; Yoder, Sean; Kunigal, Sateesh et al. (2014) ETV6 and signaling gene mutations are associated with secondary transformation of myelodysplastic syndromes to chronic myelomonocytic leukemia. Blood 123:3675-7
|Hampras, Shalaka S; Viscidi, Raphael P; Helzlsouer, Kathy J et al. (2014) Prospective study of seroreactivity to JC virus T-antigen and risk of colorectal cancers and adenomas. Cancer Epidemiol Biomarkers Prev 23:2591-6
|Chen, Ning; Chon, Hye Sook; Xiong, Yin et al. (2014) Human cancer cell line microRNAs associated with in vitro sensitivity to paclitaxel. Oncol Rep 31:376-83
|Molife, L Rhoda; Yan, Li; Vitfell-Rasmussen, Joanna et al. (2014) Phase 1 trial of the oral AKT inhibitor MK-2206 plus carboplatin/paclitaxel, docetaxel, or erlotinib in patients with advanced solid tumors. J Hematol Oncol 7:1
|Carvalho, Renato S; Fernandes, Vanessa C; Nepomuceno, Thales C et al. (2014) Characterization of LGALS3 (galectin-3) as a player in DNA damage response. Cancer Biol Ther 15:840-50
|Rizwani, Wasia; Schaal, Courtney; Kunigal, Sateesh et al. (2014) Mammalian lysine histone demethylase KDM2A regulates E2F1-mediated gene transcription in breast cancer cells. PLoS One 9:e100888
Showing the most recent 10 out of 108 publications


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Hotfrog INDIA provides information regarding KIMS Men's Hostel in Bangalore Karnataka. KIMS Men's Hostel is located at 24th Main Road, 18th Cross, Bangalore Karnataka and provides College services. Contact them on 080 2691 9704 or by visiting them on their website http://www.kimsbangalore.edu.in.
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We have more College services in Bangalore Karnataka available on Hotfrog INDIA. You can update your search for Bangalore College by location, keyword or service options.
4TH MAIN ROAD GANDHI NAGAR Bangalore Karnataka 560009
ANDREWS BUILDING Bangalore Karnataka 560001
BTM Layout Bangalore Karnataka 560076
Gundopanth Street Bangalore Karnataka 560002
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Prices and availability are subject to change from the time and date that you print this page.
2/22/2017 11:30:42 AM. For Customer Service, please call 800.933.9904
Step right up and take a look at this Jenny Lind step stool. Based on the popular Jenny Lind style, it's adorned with intricate wood turnings, giving it an elegant look. Plus, it coordinates with the rest of our Jenny Lind Furniture Collection.
Safety first
- To reduce the risk of tipping, stool should only be used by children 3 and up
- Keep surface dry to prevent slipping
Details, details
Show 'em what you're made of
The Land of Nod Guarantee
At The Land of Nod, nothing is more important to us than providing safe, high-quality products to you and your family. We believe that kids' products should be able to handle everything kids throw their way (literally and figuratively). That's why all of our products have an 18-year quality guarantee. And, hopefully, your kids will no longer be sleeping in bunk beds by then.
Knock, Knock.
Who's there?
Dwane who?
Dwane the bathtub- I'm all finished.
Who's there?
Dwane who?
Dwane the bathtub- I'm all finished.


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Jimmy Kimmel's post-Oscar show from last Sunday tops our Top Five this week.
What You Didn't See on TV During the Oscars
By: Associated Press on February 26, 2012 in 84th Academy Awards
Even the hundreds of photographers, TV cameras and webcams around the Hollywood & Highland Center can't capture every starry moment of Sunday's 84th annual Academy Awards.
Baron Cohen Spills 'Ashes' on Seacrest at Oscars
By: Associated Press on February 26, 2012 in * Homepage Cover Module, 84th Academy Awards
Outfitted extravagantly in character, Sacha Baron Cohen ran amuck on the Oscars' red carpet Sunday night and all over E! host Ryan Seacrest's tuxedo.
Tina Fey Joins Growing, Comedy-Heavy Oscar Lineup
By: Reuters on February 17, 2012 in Academy Awards, Awards Shows, Celebrities, General, The Movies, TV News
Tina Fey is the latest presenter to be announced for the 84th Academy Awards, and the third Oscar announcement to come on a very busy Friday for news from the Academy.
Tom Cruise to Present at the Oscars
By: Reuters on February 1, 2012 in Awards Shows, Celebrities, General, Oscars, TV News
Tom Cruise will serve as a presenter at the 84th Academy Awards, producers Brian Grazer and Don Mischer said Wednesday.
Tom Hanks Gets a Return Ticket to The Oscars
By: Reuters on January 31, 2012 in Awards Shows, Celebrities, General, Oscars, TV News
Tom Hanks – an Academy governor, two-time Oscar winner and five time nominee – will serve as a presenter at the 84th Academy Awards.


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Eligibility requirements and application processes vary throughout the Australia Awards programs. Please follow the links below for detailed information about the eligibility criteria and selection process for each program. Applicants must meet the eligibility criteria of the specific scholarship to which they are applying, including English language requirements.
A group of Australia Awards recipient's in conversation.
Award categories and key dates
2018 intake applications for most countries will open on 1 February 2017 and close on 30 April 2017.
2017 intake applications for Kiribati, Papua New Guinea, Samoa, Timor-Leste and Vanuatu are now closed.
2018 intake information for these countries is TBC.
Applications for Africa Short Course Awards and Masters study will close on 15 December 2016.
Applications for Bangaldesh will close on 18 November 2016.
For India scholarships, please see Australia Awards Endeavour.
All Australia Awards Scholarships opening and closing dates for the 2018 intake are listed here.
Applications for the 2017 Australia Awards -Endeavour Scholarships and Fellowships intake have now closed. All applicants (both successful and unsuccessful) will be advised of the outcome of their applications in December 2016.
Applications for the 2018 Australia Awards–Endeavour Scholarship and Fellowship round are expected to open in April 2017, and close on 30 June 2017.


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Proven RapidFire Plus shifting technology combined with compact, adjustable ergonomics.
Buy Shimano Saint 9-Speed Shifters s from Chain Reaction Cycles, the world's largest online bicycle store.
If you're not completely satisfied with an item you may return it within 12 months of purchase. We'll give you a full refund if the item hasn't been used or the component hasn't been fitted.More information on returns
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