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This group sings many different styles, from traditional Southern Gospel, to country…
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|Message view
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|List Mail User <tr...@Plectere.com>
|Re: another request for RECEIVED[x] array
|Wed, 02 Mar 2005 01:39:29 GMT
>... >List-Id: <users.spamassassin.apache.org> >Delivered-To: mailing list email@example.com >Delivered-To: firstname.lastname@example.com >... >Date: Tue, 01 Mar 2005 19:32:22 -0500 >From: "Eric A. Hall" <email@example.com> >User-Agent: Mozilla Thunderbird 1.0 (Windows/20041206) >X-Accept-Language: en-us, en >MIME-Version: 1.0 >To: Justin Mason <email@example.com> >Cc: firstname.lastname@example.com >Subject: Re: another request for RECEIVED[x] array >References: <email@example.com> >In-Reply-To: <firstname.lastname@example.com> >Content-Type: text/plain; charset=ISO-8859-1 >Content-Transfer-Encoding: 7bit >X-Virus-Checked: Checked > > >On 3/1/2005 12:37 PM, Justin Mason wrote: > >> actually, there is such a thing in SpamAssassin 3.0.x ;) e.g.: > >> debug: metadata: X-Spam-Relays-Untrusted: [ ip=188.8.131.52 >> rdns=europe.std.com helo=europe.std.com by=mail.netnoteinc.com ident= >> envfrom= intl=0 id=392E1114061 auth= ] > >This doesn't record the 'with' parameter (as in "with SMTP" or "with >ESMTP"), or any TLS info. > >> I want to have available to me are: >>> >>> 1) Check for a reverse-DNS match >>> >>> 2) Check for HELO (versus EHLO) >>> >>> 3) Check for TLS > >I already have a reverse-DNS rule coded up but I'd like to consolidate it >with the other two, but again, I really need a better view into the >transfer protocol from inside SA. > >-- >Eric A. Hall http://www.ehsco.com/ >Internet Core Protocols http://www.oreilly.com/catalog/coreprot/ > Eric, Please note that is section 4.1.4 of RFC2821 it says: "... An SMTP server MAY verify that the domain name parameter in the EHLO command actually corresponds to the IP address of the client. However, the server MUST NOT refuse to accept a message for this reason if the verification fails: the information about verification failure is for logging and tracing only. ..." The capitalization is in the original, not added. Reference from: ftp://ftp.isi.edu/in-notes/rfc2821.txt page 38, 6th paragraph of section 4.1.4 On the other hand, both sendmail and postfix can be configured to refuse messages if there is no rDNS at all for the HELO/EHLO or if the client address doesn't have any rDNS. I *would* recommend these, but since the most common MTAs already have the capability, there shouldn't be any need for SA to duplicate it. Also, the number of FPs if you attempt to enforce an exact match would be *very* high; Whenever a MTA hosts multiple domains, only one could possibly pass the test - but it is reasonable for any host which is an 'MX' for a domain to use that domain as an argument to the HELO/EHLO (and possibly - definititely allowed - for any host in a domain to use the domain name as the argument to the HELO/EHLO) . Also, note that an 'A' record isn't required (though it is recommended) - see section 188.8.131.52 and note that both sendmail and postfix will accept a "resolvable" domain as defined there (i.e. at least one 'MX' or 'A' record, and it need not match the actual client's IP address). You also have the problem of dealing with IP literals, and users running dynamic DNS which still has stale DNS data (so the response should be a 4xx code not a 5xx code, if you do something like this). If you use an SA rule, the score should be fairly low. As an example, recent mail I have exchanged with email@example.com has used escalate.hk.outblaze.com as the argument to EHLO, but the rDNS resolves to escalate.outblaze.com, and they *certainly* are not spammers (notice also, that both names resolve in different ways, but to the same IP address). Paul Shupak email@example.com
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Format PS3, Xbox 360, PC
Publisher Capcom
Reportedly, Brad Pitt may star as Dark Void's protagonistWill, a pilot who crashes in the Bermuda Triangle and ends up battling aliens, in the film-adaptation of the title. Games on screen don't exactly have a great pedigree, with Doom, Max Payne and Resident Evil all being critically panned, but theywere at least good games – Dark Void is not. The premise of a fastpaced, jet-pack shooter sounds promising, but the controls are frustrating and the graphics are crude. There is some fun to be had with the jet pack but overall, this game fails to reach its potential.
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A macroeconomic balance measure of New Zealand's equilibrium exchange rate
We estimate the fair value of the New Zealand dollar using the macroeconomic balance approach. The model's elasticities are calibrated so that they are more appropriate to a small commodity-exporting economy. Over the 1990s, the model estimates that the fair value for the TWI fluctuated between 52 and 59. For the final quarter of 1999, the model estimates that a TWI of around 56 would have been consistent with macroeconomic balance, implying that the TWI (which was around 54.5) was then approximately at fair value. However, this result is subject to a significant amount of uncertainty.
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|Date of creation:
|Dec 2000
|Contact details of provider:
| Postal: P.O. Box 2498, Wellington
Phone: 64 4 471-3767
Fax: 64 4 471-2270
Web page: http://www.rbnz.govt.nz
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Ivan Menjivar talks about his submission win over Azamat Gashimov at UFC 154, preparing for a relatively unknown opponent, and not having to travel on fight week, with MMA Fighting's Ariel Helwani. watch video >>
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text:
The Jedi or Trekkie Test
Their result for The Jedi or Trekkie Test ...
You scored 80 %Jedi and 20 %Trekkie!
Their Analysis (Vertical line = Average)
They scored 80% on Jedi, higher than 74% of your peers.
They scored 20% on Trekkie, higher than 26% of your peers.
All possible test results
-Well if you got low scores in either it probably means you are not cut out for a life in either. -If either score is higher then there is your preference. -A high score in both means you have a br... Read more
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Seo copy, link building and set up
- Status Closed
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Project Description
I am a web designer based in the UK. I am getting very busy with workload and I need to outsource some copywriting and SEO work.
I use the wordpress platform and custom themes to build my sites, but I need to work with someone to help me create content, complete the finished site and build links for seo. this would involve creating individual pages of optimised copy and then setting up the link building, Google analytics and webmaster tools, social media profiles, google places, open directory etc
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Ralphs is installing technology to reduce checkout wait time. QueVision uses infrared cameras to track body heat to determine the number of people in a store. Based on the result, workers are deployed to cash registers. QueVision has reduced Ralphs' wait time from the national average of 4 minutes to about 30 seconds, a spokeswoman says.
Full Story:Los Angeles Times (tiered subscription model)


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How do we eliminate the bias against black skin which seems to be so inextricably linked to issues of discrimination that have a real impact on the progress of African-Americans? Economic investment, legal reform and improvements in education are certainly needed. But, I also believe that positive multicultural media is part of the solution.
Rapper Ace Hood and Loud American A**hole The Fat Jew sit down and discuss waking up in a 1991 Honda Civic instead of a Bugatti, Japanese butt fetishes, his new album, instagram filters and whether Dora the Explorer will ever find what she's looking for. It's basically the best interview you've never seen.


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Our high quality, machine calligraphy services are perfect for anyone who wants the elegant look of hand calligrapy without the high cost and slow turnaround. Our calligraphy lettering bed uses real chisel-tip calligraphy pens, hand-mixed inks, and letterforms designed by master calligraphers. Choose from over a dozen fonts and ink colors. Request
Copyright © 2001-2017 OneWed Inc.
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Selecting business intelligence vendors
BI selection
Selecting business intelligence vendors News
July 07, 2016
Data science as a service provides instant access to analysts
Data scientists are in high demand, but in such scarce supply that some companies outsource their data for analysis. DataScience Inc. CEO Ian Swanson explains how it works.
February 19, 2016
Gartner shakes up annual ranking of business analytics tools
This year's Magic Quadrant report from Gartner on business intelligence and analytics platforms reflects a shifting market for BI reporting tools and includes some big changes in its vendor rankings.
January 29, 2016
Report highlights growing role for location-mapping software
A new report from Dresner Advisory Services says businesses see increased value in location intelligence software, but products need to improve.
October 22, 2015
Tableau adds Vizable mobile BI app to seek out more users
Tableau Software's new Vizable tool is a free mobile business intelligence app for iPad users, which was built as a standalone product from the company's namesake BI platform.
Selecting business intelligence vendors Get Started
Bring yourself up to speed with our introductory content
Elastic is a software company that provides products and services related to Elasticsearch, its distributed enterprise search engine. Continue Reading
Data visualization software deserves a deep look before buying
Data visualization tools can present information to business users in easy-to-grasp formats. But it isn't a pretty picture if you buy the wrong one. Continue Reading
Supermarket co-op stocks up on big data platform to help spur sales
Co-operative Allegiance Retail Services is deploying a cloud-based big data stack to replace a homegrown system that fell short on analytics power. Continue Reading
Selecting the right BI analytics tool
When determining which BI analytics tool is right for your company, it's important to separate the must-have from the nice-to-have product features.
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Evaluate Selecting business intelligence vendors Vendors & Products
Weigh the pros and cons of technologies, products and projects you are considering.
Cloud-based BI helped one company rely less on IT
Cloud-based BI helped ServiceChannel rely less on IT for data management and reporting, which freed up analysts to make stronger use of the company's data. Continue Reading
A look at SAP BusinessObjects BI suite
SAP BusinessObjects BI platform provides users with self-service access to information to support the decision-making process. Find out what's different in version 4.1. Continue Reading
Insight into Oracle Business Intelligence Foundation Suite
Oracle Business Intelligence Foundation Suite enables users to access information through interactive dashboards, search and mobile devices. Continue Reading
Manage Selecting business intelligence vendors
Learn to apply best practices and optimize your operations.
Doors opening for open source data visualization tools
Open source data visualization technologies have matured to the point where users say the available tools can handle large amounts of their visualization workloads. Continue Reading
Putting the data governance plan in self-service analytics
As self-service analytics software becomes more common, users are calling on vendors to beef up governance capabilities. Continue Reading
Cloud BI tools, hosted systems lower data analysis barriers
Cloud business intelligence platforms offer companies a faster, easier way to analyze data, thanks to reduced capital costs and streamlined system design. Continue Reading
Problem Solve Selecting business intelligence vendors Issues
We've gathered up expert advice and tips from professionals like you so that the answers you need are always available.
FAQ: Integrating and securing BI mobile apps
BI mobile apps are no longer the next big thing. They should be a key factor in any business's overall information strategy. Continue Reading
Business intelligence trends affecting the BI market, industry
Learn about some business intelligence trends that are affecting the BI market and BI industry. Learn about packaged analytics software and agile BI. Continue Reading
The real value of mobile business intelligence (BI)
Thinking about adding mobile business intelligence (BI) tools to your BI and analytics strategy? Find out where the real value of mobile BI resides and get real-world examples. Continue Reading


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The Leading eBooks Store Online
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The KoranOrion 2011; US$ 9.99
A new edition of one of the world's most important and influential books The Koran, the holy scripture of Islam, is the record of Muhammad's oral teaching delivered between the years immediately preceding the Hegira in AD 622 and the Prophet's death in AD 632. It has exerted untold influence upon the history of mankind. Apart from its specifically... more...
The Qur'anGibb Memorial Trust 2007; US$ 20.00
The Qur'an is the sacred book of Islam. For Muslims it is the word of God revealed in Arabic by the archangel Gabriel to the Prophet Muhammad, and thence to mankind. Originally it was delivered orally: traditional sources indicate that Muhammad always recited his message. He was a preacher; he delivered good news; and he warned; thus, the Qur'an... more...
Chemistry: An Introduction for Medical and Health SciencesWiley 2005; US$ 70.20
Chemistry: An Introduction for Medical and Health Sciences provides students and practitioners with a clear, readable introduction to the chemical terms and concepts that are relevant to their study and practice. Assuming little prior knowledge of the subject the book describes and explains the chemistry underlying many of the most commonly... more...
Quaternary Ammonium SaltsElsevier Science 2000; US$ 200.00
This text provides experimental methods for a wide range of organic reactions, systematically arranged according to reaction type, and describes the advantages and limitations of the procedures. Traditional methods to speed up organic reactions involve energy-consuming processes and costly and environmentally "unfriendly" solvents. Additionally,... more...
Terry Jones' BarbariansEbury Publishing 2009; US$ 14.09
Terry Jones' Barbarians takes a completely fresh approach to Roman history. Not only does it offer us the chance to see the Romans from a non-Roman perspective, it also reveals that most of those written off by the Romans as uncivilized, savage and barbaric were in fact organized, motivated and intelligent groups of people, with no intentions of... more...
Terry Jones' Medieval LivesEbury Publishing 2009; US$ 12.68
Was medieval England full of knights on horseback rescuing fainting damsels in distress? Were the Middle Ages mired in superstition and ignorance? Why does nobody ever mention King Louis the First and Last? And, of course, those key questions: which monks were forbidden the delights of donning underpants... and did outlaws never wear trousers? Terry... more...
Saturday Night ForeverMainstream Publishing 2011; US$ 11.27
If all disco means to you is records like 'I Will Survive' and 'YMCA', tacky fashions and glitter eyeshadow, this book will be a real revelation. For Alan Jones and Jussi Kantonen, disco was an essential soundtrack to their lives. They loved its total hedonistic excess, its drive, its punch and its sweet, catchy melodies. For every chart hit that... more...
The Bonus of LaughterFaber & Faber 2012; US$ 18.95
Alan Pryce-Jones (1908-2000) had a gift for living, for moving between countries and occupations, and above all for enjoying himself throughout. His memoir offers a highly entertaining account of these varied peregrinations and preoccupations. After Eton and Oxford and a stint on the London Mercury he married and moved to Vienna, joined the army... more...
BloodlineAtria Books 2014; US$ 17.00
Two individuals from different countries but who share one ancestral bloodline race to thwart a terrorist plot in Jerusalem?the first heart-pounding book in a new epic trilogy that delves into the dark underbelly of the Holy City. Bilal, a radicalized Palestinian youth, is promised paradise if he destroys the Western Wall. But his attempted terrorist... more...
BirthrightAtria Books 2015; US$ 16.00
The dramatic fight for modern Jewish statehood forms the backdrop of this second book in the Heritage trilogy, a series of epic political thrillers set in Jerusalem. Following Bloodline , in which Bilal and Yael raced to thwart a terrorist plot in modern-day Jerusalem, Book Two travels six decades into the past and introduces Yael?s grandparents:... more...


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All Entries Tagged With: "Stronghold 3: The Campaigns"
Stronghold 3's First Mission Offered in New Detailed Walkthrough Video
Posted by Mary Ann Neder | Jun 13, 2014 | Comments 0Digital Tribe Games, the premier global publisher for independent game developers, has created a new tutorial video in preparation for its upcoming launch of the anticipated title Stronghold 3: The Campaigns for iPad. Learn how to build, farm and protect your castle.
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U-Haul Office Clerk in COLUMBUS, Ohio
Office Clerk
U-Haul Repair FacilitiesColumbus RERSCOLUMBUS , OH
Perform a variety of general clerical/basic accounting duties to provide support to shop personnel. Prepare reports, correspondence, memos, etc. Maintain office files and order supplies. Answer telephones, take messages, prepare outgoing mail. Should have basic working knowledge of operating a personal computer.
Position requires a valid driver's license and a good driving record to operate a motor vehicle. Adhere to all local vehicular regulations while driving.
Work Environment:
The work involves moderate risks or discomforts which require special safety precautions, e.g., working around moving parts or machines, fumes or irritant chemicals. May be required to use protective clothing, or gear such as masks, goggles, gloves or shields.
Physical Demands:
The work requires some physical exertion such as long periods of standing, walking, recurring bending, crouching, stooping, stretching, reaching or similar activities, and lifting a minimum of 50 lbs assisted or unassisted.
Work Status:
Hours Needed:
(These hours may change based on business needs)
Sun –NA
Mon –7am to 3pm
Tue –NA
Wed –NA
Thu –7am to 3pm
Fri –7am to 3pm
Sat –NA


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text: 8/11/2014 5:27:27 AM 16 9 PathlessDemon Customizable Shaders Just an idea, but having the ability to build a custom shade/color mechanism for armor sets at the cost of glimmer for players. #feedback Comment Reply Start Topic Report Add more answer options B I U Quote Link Named Link Spoiler Armory Forum Category Destiny Feedback Help Community Recruitment Gaming OffTopic Forum Sub-Category Post a Poll Question Post Cancel Edit Create Fireteam Post Play nice. Take a minute to review our Code of Conduct before submitting your post. View Entire Topic


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Apartment Vienna - Entire
Størrelse38 m²
Etage3(med elevator)
- Familie/børnevenlig
- Internet/WIFI
- Køkken
- Kæledyr tilladt
- Vaskemaskine / tørretumbler
- Parkering tilgængelig
- Elevator i bygningen
Oversigt over boligen
|Stuwerstraße, 1020 Vienna, Østrig
|Inden for få timer
|Kalenderen er opdateret
|I dag
This holiday apartment offers room for up to 4 guests and is fully equipped: washing machine, iron, hair dryer, LCD TV, DVD player, free internet, kitchen, coffee machine, microwave oven, and many more. The complete and newly outfitted Vienna holiday apartment is situated on the third floor, with elevator on site.
• Parking garage € 16/24h in the proximity (Stuwerstraße 41)
• Central location with excellent infrastructure connections
• Praterstern - public transportation in every direction and a good number of stores
• Underground station Prater-Messe U2, bus 82A
• 5 min. to Stephansplatz, Danube Island (Donauinsel)
• Fully equipped apartment - dishwasher, coffee machine
• Kitchen, washing machine, iron, hair dryer, silver ware, drinking glasses, children's bed, etc.
• Sofa bed, 160 x 200 cm, double bed, 180 x 200 cm
• Free of charge internet, wireless LAN, Flat HDTV, DVD-player
• Premium equipment
• Elevator/Lift
Other amenities consist of dishwasher, coffee machine, kitchen, washing machine, iron, hair dryer, silver ware, drinking glasses, children's bed, sofa bed, double bed, WiFi internet, flat HDTV, DVD-player, towel and linen service, premium equipment, elevator/lift.
The city accommodation Stuwerstrasse is located a mere 3-minute-walk from the underground station Messe/Prater and lies directly at the Viennese Prater park with its famous landmark: the Viennese ferrous wheel (Riesenrad), the fair grounds, and the University of Economic Sciences.
We can provide parking space in a garage (check rules).
This is a central location with excellent infrastructure connections: Praterstern - public transportation in every direction and a good number of stores; underground station Prater-Messe U2, bus 82A.
It's 5 minutes to Stephansplatz, Danube Island (Donauinsel).
From the underground station Messe/Prater you arrive in only a few minutes in the historic city center of Vienna - where further well known landmarks such as the Stephansdom, the Kärtnerstraße, the State Opera, the Museum of Art History, the Hofburg, the Emperor's Crypt, etc. can be found. At the Danube canal (Schwedenplatz-Urania Station), only 5 minutes by underground, you'll find the departure dock of the Twin City Liners passenger boats which shuttle between Vienna and Bratislava.
The entire holiday accommodation Stuwerstrasse is situated next to the largest part of the second district - the Prater park. The Lusthaus, a historical building, that was a beloved meeting place for the nobility and the upper middle class in the 19th century. Nowadays the Lusthaus is a café / restaurant. Not far from the Lusthaus is the Ernst-Happel stadium where the final game of the 2008 European soccer championship was played. In the Prater river bank area lies the harness racing track Krieau, the horse racing track, and a golf club.
The Wurstelprater offers a great variety of traditional Viennese gastronomic delights at establishments such as: the Schweizerhaus, well known for its plentiful supply of Budweiser beer and their roast leg of pork.
From the apartment and taking the subway, you'll arrive in just a few minutes to the Danube Island (Donauinsel) which hosts the annual 3-day open-air festival, the largest music festival in Europe, which is well known for its recreational facilities and can be reached by the underground U1 in just 2 stops.
Located in the immediate vicinity of the apartment - is the Karmelitermarkt. A market celebrated for its international delicatessen shops, pubs and restaurants and events. Nice taverns and youthful art help make the Karmelitermarkt an exciting Viennese neighborhood. On Friday and Saturday, until noon, you can buy fresh products there and enjoy the atmosphere while taking pleasure in a good glass of wine. Exhilarating food and modern art make the locale around the Karmelitermarkt a stimulating Viennese quarter.
HusreglerPlease be aware that we have no front desk.
But we will welcome you at the appointed time in the apartment.
Parking garage € 16/24h in the proximity (Stuwerstraße 41)
|Ugentlig pris for op til 2 gæster
|Månedlig pris for op til 2 gæster
|Pris for > 2 gæster
|31 DKK pr. gæst/ekstra nat
|Check-in efter
|Check-in før
|Efter aftale
|Check ud før
Anmeldelser af denne værts andre boliger
Meget flot lejlighed, meget ren og godt placeret. Fremragende kvalitet / pris forhold!
Très joli appartement, très propre et bien situé. Excellent rapport qualité/prix !
Vi har haft et prægtigt ophold i Wien. Vor lejlighed var fantastisk, der fandtes alt hvad hjertet kunne begære, samt meget centralt, vil gerne komme igen og kan anbefale boligen til alle.
Very nice, rolige, lyse lejlighed. Gode transportforbindelser til byens centrum og lufthavnen. Lejligheden har alt hvad du behøver for et behageligt ophold. Selv en vaskemaskine. Vi havde meget behagelige dage i Wien og vil vende tilbage. Lejlighed stærkt anbefales.
Sehr schöne, ruhige, helle Wohnung. Super Verkehrsanbindung ín die Innenstadt und zum Flughafen. Die Wohnung hat alles was man für einen angenehmen Aufenthalt braucht. Sogar eine Waschmaschine. Wir hatten sehr schöne Tage in Wien und kommen gerne wieder. Wohnung sehr zu empfehlen.
en god og pæn lejlighed, beliggende nær metro, men ikke ideel til kørestol bruger i forbindelse med små og kun tilgængelige med elevator kælder (elektrisk kørestol er alligevel ikke muligt).
een goed en netjes appartement, vlakbij metro gelegen; maar voor rolstoelgebruiker niet ideaal ivm kleine lift en alleen toegankelijk via kelder.(elektrische rolstoel is zowiezo niet mogelijk!)
Lejligheden er ideel for 2 personer. Meget flot badeværelse!
Die Wohnung ist Ideal für 2 Personen. Sehr schönes Bad!
Lejligheden var meget rart.
Små, men godt udstyret. Placeringen var også meget praktisk, ikke i det historiske centrum, men en metrostation rundt om hjørnet.
The apartment was very nice.
Small, but good equipped. The location was also very practical, not in the historical center but a subway station around the corner.
Dejlig nyrenoveret og ren lejlighed. Enkel indretning. Super med vaskemaskine og tørretumbler i en maskine. Dejligt, at der var vaskepulver. De fleste i familien har et godt sovehjerte - heldigvis, fordi der var megen larm fra store kraner, gravemaskine m.m. Super med en altan. Ok beliggenhed. U-bahn og sporvogn lige uden for døre. Disse kørte til centrum. Supermarked og parkeringskælder meget tæt på. Internettet virkede upåklageligt. Vi vil bestemt anbefale lejligheden til andre.
We had a very pleasant stay at this appartment. It is really perfect, brand new and very complete (with washingmachine, dishwasher, satelite TV). It was really pleasant to sit on the balcony. The bed and the shower are exellent, Also the location is good with the tramway nr 2 to take you down town. We were by car and could park in a garage around the corner and in the weekend free in front of the door or in the street around the corner. Vienna is a wonderfull city, and we would recommend the city as wel as the appartment very much.
We arrived at the apartment on a very hot afternoon. The apartment is located on the sixth floor which is almost the top floor of the building. Unfortunately this meant that inside the apartment the temperature was as high as outside (>30degC). The apartment looked just as in the pictures, very modern and bright. When it was time to go to sleep we discovered that the sheets were still damp from the dryer. Due to the heat we didn't need the covers so this wasn't a real issue but still something you wouldn't expect. The bed could use a little tweaking because it was very loud when one turned. Also a minor disappointment was the lack of supplies. No sugar, tea, coffee or oil. The only thing there was salt and coffee filters.
The pull-out sofas are high quality. In fact I slept better on the sofabed than on the real bed.
Location is perfect, very close to the metro and a tramstop (line 2 will take you directly to the the Vienna ring).
Even though it was very hot we had a great time in Vienna.
We enjoyed our stay at the apartment which we found to be very comfortable and well equipped, and it was nice to be able to sit out on the balcony. While at first the apartment appeared to be a way from the centre, the close proximity of the underground and trams made this journey very easy.
- Kvalitetssikrede boliger
- Alle værter verificeres via telefon
- Sikker betaling med SSL-kryptering


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Pressed on Animal Rights, Researcher Gives Up Grant
Published: November 22, 1988
(Page 2 of 2)
Interpreting this as a pledge that the research on cats had ended, Trans-Species stopped protesting. But Cornell officials say it merely meant that Dr. Okamoto would gradually be shifting her research to rats.
Indeed, in the fall of 1987, with Cornell's approval, Dr. Okamoto applied for a four-year NIDA grant for three years of experiments with cats, followed by one year with rats.
When Trans-Species heard the proposal involved cats, it renewed its protests and accused Cornell of lying. Rat Portion Is Rejected
In July 1988, the institute approved the cat research, but said it was unconvinced that the rat experiments were crucial and so would not pay for them. Scientists there said funds are scarce and the institute frequently approves just part of a proposal.
Dr. Okamoto was awarded $390,000 for the direct costs of the experiment; on top of that, Cornell was to receive about $200,000. Officials at NIDA said that with inflation and other costs, the total award might have come to $750,000 over three years.
So institute officials were stunned when Dr. Okamoto wrote to them on Sept. 22 returning the grant.
Saying that her decision was reached ''regretfully and with deep disappointment,'' she wrote: ''As much as I want to continue my long interest in the study of the mechanisms of drug dependency using the feline model, recent developments both outside and inside the University have made it difficult for me to proceed with the experiments as proposed in my renewal grant.''
Cornell says she freely chose to return the money. Her colleagues say the school pressured her into it. Dean Denies Pressure Applied
The dean of Cornell Medical College, G. Thomas Shires, said last week that there had been no pressure. Dr. Okamoto was disappointed at not getting a four-year grant, he said, and felt her project would not be meaningful unless she could move toward rat research.
''She agreed that since it was not a transition grant,'' he said, meaning the transition from cats to rats, ''she was happy to turn it down.''
Dr. Mishkin retorted: ''That's an absolute falsehood. Of course they pressured her.''
Saying he discussed the case at length with Dr. Okamoto several days ago, he added: ''It is my understanding that she agreed to become involved in the rat research partly under the pressure that was being exerted on her to ultimately change species.'' Public Relations Played Part
The dean acknowledged that public relations also played a part in the decision to give up the grant. The university, already embarrassed by the confusion over its letter, would have looked still worse if Dr. Okamoto had gone ahead with cat experiments without the subsequent rat research, he said.
''Cornell would have had no credibility at all,'' he said.
He added that Dr. Okamoto had volunteered to switch to her current project, a study of alcohol dependency using rats, that Cornell will finance alone. Dr. Mishkin disputed that as well. ''This is sleaze,'' he said. ''It's an attempt by Cornell to get out of a difficult situation and put the onus on her.''
Mr. Siegel of Trans-Species said he was disappointed that rats, or any animals, would be used. Still, he called the decision to give back the grant ''a positive step.''
''Cornell has been made to be responsive to the people,'' he said. ''I'm unhappy about one rat dying, but I know that Cornell thinks it's a step down on the evolutionary scale.'' Animal Rights Groups Stronger
The decision to return the grant -regardless of whose decision it was -illustrates the growing strength of animal-rights groups.
In the last few years, hundreds of them have sprung up, while older ones have gained momentum and money.
People for the Ethical Treatment of Animals, which closed a head-injury lab at the University of Pennsylvania in 1984 by distributing videotapes of conditions inside, now has 250,000 volunteer members nationwide. Four years ago, it had just 20,000.
''You're going to be seeing an increase in activity,'' Carol Burnett, a spokeswoman for the group, said. ''We have more money and staff and can do the research.''
Frankie L. Trull, president of the National Foundation for Biomedical Research, which represents research institutions that use animals, said of the opposition: ''Their propaganda is slicker. They target areas of research for which the public does not have good understanding. They develop sympathy from the animal-loving public.'' Sometimes, Bombs or Arson
Occasionally, animal-rights advocates go so far as to bomb, set fire to or break into laboratories. And this month, the police arrested a Queens woman on charges of planting a bomb outside a Connecticut research laboratory that uses dogs in experiments.
At the same time, many groups are turning to methods like those used in the effort against Dr. Okamoto, including obtaining Government documents through the Freedom of Information Act and circulating reports by doctors denouncing the experiments.
Biomedical researchers say they welcomed some advances made in the early stages of the movement, when the focus was on how laboratory animals were treated, not on whether they were used at all. But they say - and the animal rights supporters agree -that it is impossible to debate when the two sides are so at odds.
''They're arguing a fundamental position of the inherent rights of animals that says animals are equal to people in terms of using them for experiments - it is a position I have no sympathy for,'' said Dr. David Korn, dean of the Stanford University School of Medicine.
''The issue of academic freedom is a big, fat red herring,'' said Dr. Murry J. Cohen, chief of the psychiatric outpatient clinic at Lenox Hill Hospital and a member of Trans-Species. As far as he is concerned, he said, the only animal appropriate for experimentation would be a one-celled animal.
''It would be pretty hard to do a heart transplant on a paramecium,'' countered Larry N. Horton, associate vice president for public affairs at Stanford.
Photo of Steve Siegel (pg. B5) (NYT/Fred R. Conrad)


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Laser hair removal is considered a popular cosmetic procedure these days. Many people actually have problems of unwanted hair growth on various parts of the body. Some people find these hair growths embarrassing or unsightly. However, other people just want to lessen the need for waxing, shaving or tweezing. With laser hair removal, unwanted hair growth is significantly reduced. This procedure may be performed on the back, legs, face, forearm, bikini line, and underarm. Aside from reducing hair growth, this procedure can also be used to permanently lessen the amount of hair in certain parts of the body.
How Does Laser Hair Removal Work?
Laser hair removal works by light energy. A laser will be used to emit light energy, which travels through the skin. In addition, the pigment found in the hair shaft and the hair follicle absorbs this. The laser will work through selective photothermolysis. This means that the light energy will be absorbed by the pigmented areas in the skin. Those hair follicles in their active growth phase will have the largest amount of pigment or melanin and they will absorb the light energy emitted by the laser.
On the other hand, hair follicles that are in the catagen or the telogen phase are less pigmented. Hair growth for these follicles is not diminished. The energy from the laser will damage those hair follicles in its active growth phase. This impairs its ability to grow hair. The hair on these follicles will eventually fall out, which results in a smoother appearance as well as less hair growth in the area.
Laser Hair Removal Procedure: What Happens During and After the Procedure?
In Atlanta, a laser hair removal Atlanta specialist or expert performs laser hair removal. During the procedure, the laser hair removal Atlanta specialist will guide the laser over the body part that will be treated. The laser will pulse intermittently to deliver light energy. The energy travels through the skin and absorbed by the follicles of the hair. The follicles will be damaged and the hair will eventually fall out. In addition, the follicle's ability to grow hair will become impaired.Since not all hair follicles are in their active growth phase, several sessions may be performed. The number of treatments varies. A laser hair removal Atlanta specialist will recommend about six to nine laser removal sessions to completely reduce hair growth in a single part of the body.
For more information please visit: IPL Atlanta


text: The Matrimony Of MimiTracie Egan Morrissey5/01/08 1:45pmFiled to: Mariah CareyWeddingsda bratmimiNick Cannon100EditPromoteShare to KinjaToggle Conversation toolsGo to permalink Mariah Carey isn't just engaged — she's married! Latina magazine is reporting that they have confirmation that Mariah and Nick Cannon had a "very impulsive" wedding on an island on Wednesday, attended by a few close friends of the couple, one of them being Da Brat. It is the second marriage for the 38-year-old bride, and the first for her 27-year-old groom. Congrats! [Latina via Perez]Reply100 repliesLeave a reply


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Arts , Youth , Education , incarcerated , Foster Youth , performing arts , Writing , gang members , Creative Arts , children , , , , , , , , , , , , , , , , , Ver más
Create Now
Por el momento no tenemos ninguna oportunidad de voluntariado, trabajo o eventos.
Ingresa o regístrate para enterarte cuando nuevos avisos o eventos sean publicados!
Sobre nosotros
Create Now, a 501 (c)(3) non-profit organization founded in 1996, helps transform the lives of youth in need through arts mentoring and experiences. The organization serves vulnerable kids ages 2-21 who have been abused, neglected, abandoned, orphaned, are left homeless, runaways, teen parents, substance abusers, victims of domestic violence, children of prisoners, gang members or incarcerated. Through music, dance, art, writing and cultural excursions, we help build needy youths' self-esteem and career goals. We've reached 35,000 of the most troubled youth in Southern California during the last 18 years.
Through our five program areas; music, art, writing, performing arts and cultural excursions, troubled youth learn to express themselves in a positive manner versus the destructive ways that they have in the past. We also bring thousands of these kids to free concerts, plays and other cultural events at premiere venues throughout the region. These field trips not only educate youth while exposing them to new types of music, theater and art, but also bring them relief and joy.
Create Now programs develop vital skills and build teamwork, self-esteem and confidence. In addition, we send out regular notices about jobs, internships, scholarships, free books, computers, arts supplies and other materials to the 100+ partners in our network, such as shelters, group homes, detention camps and other youth agencies serving hundreds of thousands of needy youth.
If you'd like to become an arts mentor or administration volunteer for Create Now please complete our volunteer application at http://www.tfaforms.com/212588.
Palabras clave
Información de contacto
Fecha de creación: 10/26/96
Número de identificación del gobierno: 95-4590574
Email: Ingresa para ver las direcciones de email.
Página(s) web:
createnow.org tfaforms.com/212588
Teléfono: 213-747-2777
Fax: 213-341-2408
1611 S. Hope Street, # E, Los Angeles, CA, 90015, US


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Epstein-Barr virus (EBV) is a human herpesvirus that infects both B lymphocytes and epithelial cells. Depending upon cell type and differentiation state, infection leads to lytic replication with cell death or latent infection. Latent infections are associated with several epithelial- and B-cell malignancies. By identifying key cellular factors and pathways regulating EBV latency and lytic replication and drugs that affect their activities, we hope to develop "lytic induction" therapies for treating patients with EBV-associated cancers. The immediate- early BZLF1 and BRLF1 genes of EBV encode multifunctional proteins essential for lytic replication. While transcription from their promoters, Zp and Rp, respectively, is strongly silenced in latently infected cells, cell differentiation and factors activated by signaling pathways can induce their expression, leading to reactivation into lytic replication. We have identifled several physiologically relevant factors that play key roles in regulating this switch: ZEB1, ZEB2, p53, Oct-1, Oct-2, Smads via TGF-p signaling, and the Zp ZIIR element. We have preliminary data indicating important roles as well for HIF-1 a, Pax5, and Blimp-la and have identified 2 drugs, nufiin-3 and L-mimosine, that induce EBV reactivation via effects on some of these factors. We have developed a mouse model with a humanized immune system that can be use to examine factors affecting EBV-induced tumorigenesis and effects of drugs on growth and killing of EBV+ lymphomas. We have also identified a non-tumorigenic epithelial cell line, NOKs, in which we can study effects of differentiation state on EBV's life cycle. Here, we propose to determine: (i) how HIF-1 a, the ZEBs, PAX5, and Blimp-la play key roles in controlling EBV's latent-lytic balance in cells in culture, during differentiation of EBV+ NOKs and B cells, and in humanized mice;and (ii) whether nufiin-3 or L-mimosine together with HDAC inhibitors can efficiently reactivate EBV, leading to highly selective killing of some types of EBV+ cells lines in culture and tumors in humanized mice, especially when used in combination with ganciclovir, a nucleoside analog prodrug activated by a virus-encoded kinase. The findings obtained from these experiments will identify key cellular factors and pathways that regulate the balance between latency and lytic replication of EBV in epithelial and B cells, may identify effective lytic-inducing drugs for treating EBV-associated cancers, and may lead to a candidate vaccine for immunization against EBV by identifying an EBV mutant unable to establish viral latency. Drs. Kenney and Mertz collaborate extensively, including holding bimonthly joint research group meetings and co-authoring publications in which both labs made key contributions.
Epstein-Barr virus (EBV) is a ubiquitous human herpesvirus associated with several types of cancers. This project is designed to identify drugs that effectively reactivate this virus out of latency into lytic replication to use for treating patients with EBV-associated cancers. This work may lead to a candidate vaccine for immunization against EBV.
|Park, Jung Wook; Nickel, Kwangok P; Torres, Alexandra D et al. (2014) Human papillomavirus type 16 E7 oncoprotein causes a delay in repair of DNA damage. Radiother Oncol 113:337-44
|Wang, Lu; Zhao, Zibo; Meyer, Mark B et al. (2014) CARM1 methylates chromatin remodeling factor BAF155 to enhance tumor progression and metastasis. Cancer Cell 25:21-36
|Kuzembayeva, Malika; Hayes, Mitchell; Sugden, Bill (2014) Multiple functions are mediated by the miRNAs of Epstein-Barr virus. Curr Opin Virol 7:61-5
|Wang, Joseph Che-Yen; Nickens, David G; Lentz, Thomas B et al. (2014) Encapsidated hepatitis B virus reverse transcriptase is poised on an ordered RNA lattice. Proc Natl Acad Sci U S A 111:11329-34
|Stein, Andrew P; Saha, Sandeep; Yu, Menggang et al. (2014) Prevalence of human papillomavirus in oropharyngeal squamous cell carcinoma in the United States across time. Chem Res Toxicol 27:462-9
|Iempridee, Tawin; Reusch, Jessica A; Riching, Andrew et al. (2014) Epstein-Barr virus utilizes Ikaros in regulating its latent-lytic switch in B cells. J Virol 88:4811-27
|Park, J W; Shin, M-K; Lambert, P F (2014) High incidence of female reproductive tract cancers in FA-deficient HPV16-transgenic mice correlates with E7's induction of DNA damage response, an activity mediated by E7's inactivation of pocket proteins. Oncogene 33:3383-91
|Shrestha, Prabha; Sugden, Bill (2014) Identification of properties of the Kaposi's sarcoma-associated herpesvirus latent origin of replication that are essential for the efficient establishment and maintenance of intact plasmids. J Virol 88:8490-503
|Vereide, D T; Seto, E; Chiu, Y-F et al. (2014) Epstein-Barr virus maintains lymphomas via its miRNAs. Oncogene 33:1258-64
|Son, Jieun; Park, Jung Wook; Lambert, Paul F et al. (2014) Requirement of estrogen receptor alpha DNA-binding domain for HPV oncogene-induced cervical carcinogenesis in mice. Carcinogenesis 35:489-96
Showing the most recent 10 out of 358 publications


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Red Hat CEO Jim Whitehurst to Deliver Keynote Address at The Cloud Factory
April 2, 2014
Premiere enterprise technology conference will discuss disruptive innovations in cloud computing, big data and enterprise technology
RALEIGH, N.C. – APRIL 2, 2014 – Red Hat, Inc. (NYSE: RHT), the world's leading provider of open source solutions, today announced that its president and CEO, Jim Whitehurst, will be delivering the opening remarks at The Cloud Factory on April 8, 2014.
In his keynote, Whitehurst will discuss how the evolution of business, technology and innovation has led us to the cloud, and will also share his thoughts on how cloud is impacting enterprise.
The Cloud Factory is a premiere two-day enterprise technology conference to be held in the resort town of Banff, Alberta, Canada on April 7-8, 2014. The conference will bring together senior enterprise executives, corporate M&A teams, venture capitalists, startups, industry disruptors, technology thought leaders and global media to discuss disruptive innovations in cloud computing, big data and enterprise technology. Each day will focus on a distinct theme – Democratizing the Enterprise, and Growth Hacking the Enterprise – and will feature keynote presentations, fireside chats, panel discussions, startup pitches, demo alleys and post-event excursions and activities. The Cloud Factory is billed as the biggest enterprise technology conference in the history of Canada.
WHAT: Red Hat president and CEO Jim Whitehurst opening remarks
WHERE: The Banff Center, 107 Tunnel Mountain Dr. Banff, Alberta T1L 1H5, Canada
WHEN: Tuesday, April 8, 2014, 9 a.m. MT
For more information on The Cloud Factory, visit http://thecloudfactory.io/
Connect with Red Hat
About Red Hat, Inc.
Red Hat is the world's leading provider of open source software solutions, using a community-powered approach to reliable and high-performing cloud, Linux, middleware, storage and virtualization technologies. Red Hat also offers award-winning support, training, and consulting services. As the connective hub in a global network of enterprises, partners, and open source communities, Red Hat helps create relevant, innovative technologies that liberate resources for growth and prepare customers for the future of IT. Learn more at http://www.redhat.com.
Forward-Looking Statements
Certain statements contained in this press release may constitute "forward-looking statements" within the meaning of the Private Securities Litigation Reform Act of 1995. Forward-looking statements provide current expectations of future events based on certain assumptions and include any statement that does not directly relate to any historical or current fact. Actual results may differ materially from those indicated by such forward-looking statements as a result of various important factors, including: risks related to delays or reductions in information technology spending; the effects of industry consolidation; the ability of the Company to compete effectively; the integration of acquisitions and the ability to market successfully acquired technologies and products; uncertainty and adverse results in litigation and related settlements; the inability to adequately protect Company intellectual property and the potential for infringement or breach of license claims of or relating to third party intellectual property; the ability to deliver and stimulate demand for new products and technological innovations on a timely basis; risks related to data and information security vulnerabilities; ineffective management of, and control over, the Company's growth and international operations; fluctuations in exchange rates; and changes in and a dependence on key personnel, as well as other factors contained in our most recent Quarterly Report on Form 10-Q (copies of which may be accessed through the Securities and Exchange Commission's website at http://www.sec.gov), including those found therein under the captions "Risk Factors" and "Management's Discussion and Analysis of Financial Condition and Results of Operations". In addition to these factors, actual future performance, outcomes, and results may differ materially because of more general factors including (without limitation) general industry and market conditions and growth rates, economic and political conditions, governmental and public policy changes and the impact of natural disasters such as earthquakes and floods. The forward-looking statements included in this press release represent the Company's views as of the date of this press release and these views could change. However, while the Company may elect to update these forward-looking statements at some point in the future, the Company specifically disclaims any obligation to do so. These forward-looking statements should not be relied upon as representing the Company's views as of any date subsequent to the date of this press release.
Red Hat is a trademark of Red Hat, Inc., registered in the U.S. and other countries. Linux® is the registered trademark of Linus Torvalds in the U.S. and other countries.
Media Contact:
Emily Stancil Martinez
Red Hat, Inc.
(919) 301-3010
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--- In iris-photos@y..., jem300@a... wrote:
> Wow,Laurie. That is amazing. Thanks for sharing the photos.
> Conjuration is another tall growing iris here. How about you?
I acquired CONJURATION as a tiny increase last year from a friend, and
it's likely to be another year or two before it reaches blooming size.
I'll be watching it closely, though. Thanks for the heads up. :-)
My next tallest stalk this year was BAYBERRY CANDLE which topped out
at 40 1/2".
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President's Council
Chairman's Circle
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PHILADELPHIA -- Rain forced postponement Saturday of the game between the Florida Marlins and Philadelphia Phillies and a pitching matchup of Sergio Mitre and Brett Myers.
The game was rescheduled for July 30 at 7:35 p.m. as part of a split doubleheader. The first game starts at 1:35 p.m.
The rainout pushed Mitre (1-1) and Myers (1-0) back a day and they are expected to pitch on Sunday.
It was the second home rainout this season for the struggling Phillies, who have lost three of four after a 4-2 road trip. Philadelphia is just 2-8 at home.


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Hot pepper sauce is made with green tabasco peppers and vinegar. Don't confuse this product with hot sauce, which is red and fiery hot.
4 servings (serving size: 1 chicken breast half)
More from Oxmoor House
Nutritional Information
Calories 253
Caloriesfromfat 0.0 %
Fat 7.6 g
Satfat 3.5 g
Monofat 0.0 g
Polyfat 0.0 g
Protein 42.2 g
Carbohydrate 1.5 g
Fiber 0.2 g
Cholesterol 115 mg
Iron 1.6 mg
Sodium 431 mg
Calcium 122 mg
1/2 cup (2 ounces) crumbled feta cheese with basil and sun-dried tomatoes
2 tablespoons minced green onions
1 teaspoon extravirgin olive oil
1/2 teaspoon dried basil
1 tablespoon country-style Dijon mustard
1/2 teaspoon hot pepper sauce
4 (6-ounce) skinless, boneless chicken breast halves
Cooking spray
1/8 teaspoon freshly ground black pepper
1. Preheat oven to 350°.
2. Combine first 4 ingredients in a small bowl; toss gently. Set aside.
3. Combine mustard and hot pepper sauce; stir well.
4. Place chicken on a broiler pan coated with cooking spray. Spread mustard mixture evenly over chicken. Bake at 350° for 20 minutes. Sprinkle evenly with cheese mixture. Bake 5 more minutes or until cheese melts slightly. Sprinkle with black pepper.
carbo rating: 1
January 2005


text:
Red Linen Chambray Towels
Product: Red Linen Chambray Towels
Retailer: Fog Linen Work
Color: Red
Thick chambray weave linen that is long-lasting and absorbent. Each towel has a handy loop sewn in for hanging.
If you decide to put these in the dryer, they are going to shrink up slightly, but get really soft and that's what makes these even better!
- W 75cm x L 145cm
- 29.5″ x 57″
- 100% linen
- machine wash gentle/dry cool or line-dry


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Dave Brockie net worth: Dave Brockie was an Canadian-American rock musician who had a net worth of $50 thousand dollars. Dave Brockie was the lead singer of the shock rock metal band Gwar. He was perhaps better known by his stage name Oderus Urungus. Brockie was born on August 30, 1963 in Ottawa, Ontario, Canada. He died on March 23, 2014 in Richmond, Virginia. The cause of his death is not yet known, but Brockie was found sitting upright in a chair by a bandmate. During its more than 30 year career, Gwar released 12 studio albums, nine singles, two compilation albums and two live albums. Their 1988 debut album "Hell-O" was certified Gold in the US and double platinum in Germany. Several more albums were certified at least Gold. The band seemed to find a particular popularity in Germany, where their concerts were frequently sold out way in advance and their albums sold well consistently. Gwar was known for their shock-rock lyrics and wild stage shows that included the band members wearing elaborate costumes. The were nominated for two Grammys during their career, once for best long-form video in 1992 and a second time for best metal performance. Brockie started out as one of the band's three guitarists. He then went on to play bass before becoming the Gwar's official lead vocalist.
Dave Brockie Net Worth
Dave Brockie
Date of Birth
Singer, Musician, Bassist, Actor
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All net worths are calculated by applying a proprietary algorithm. The results are then fact checked and confirmed by a team of editors. We scan all publicly available data and resources and work diligently to ensure that our numbers are the most accurate and up to date net worth data you will find anywhere on the internet.


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The Third Bill Slider Omnibus
By (author) Cynthia Harrod-Eagles
Format: Paperback
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Third Bill Slider Omnibus by Cynthia Harrod-Eagles
Book DescriptionSHALLOW GRAVE: The Old Rectory is the kind of house Detective Inspector Bill Slider would give anything to own. But the dead body of Jennifer Andrews, found in a hole on the terrace, rather spoils the view. It looks like a straightforward case: Jennifer was a congenital flirt, and the hole was dug by her builder husband Eddie, who was violent and jealous. But questions remain unanswered. Why was Jennifer's body so unmarked? And how did she reach her shallow grave unnoticed? BLOOD SINISTER: Award-winning ex-Guardian hack Phoebe Agnew had a name for championing the underdog - and for attacking the police in print. When her trussed and strangled body is found in her chaotic flat, Detective Inspector Slider must demonstrate the impartiality of the law and find her killer. Unidentified fingerprints, a missing ligature, alibis offered when none is required - Slider is on a race against time to untangle the web of lies and hidden relationships.
Buy Third Bill Slider Omnibus book by Cynthia Harrod-Eagles from Australia's Online Bookstore, Boomerang Books.
Book DetailsISBN: 9780751539486
(197mm x 127mm x 33mm)
Pages: 544
Imprint: Sphere
Publisher: Little, Brown Book Group
Publish Date: 1-Feb-2007
Country of Publication: United Kingdom
Books By Author Cynthia Harrod-Eagles
Long, Long Trail, Hardback (June 2017)
The fourth book in the War at Home series by the author of The Morland Dynasty novels. Set against the evocative backdrop of World War I, this is an epic family drama featuring the Hunters and their servants
Land of My Dreams, Paperback (December 2016)
The third book in the War at Home series by the author of The Morland Dynasty novels. Set against the evocative backdrop of World War I, this is an epic family drama featuring the Hunters and their servants
Old Bones, Hardback (October 2016)
A couple discover human remains buried in the garden of their new house: could this be the resting place of 14-year-old Amanda Knight, who disappeared from the same garden two decades before? With a murder twenty years in the past, this is the coldest of cold cases. Most of the suspects are now dead too, and all passion is long spent. Or is it?
One Under, Hardback (August 2016)» View all books by Cynthia Harrod-Eagles
A middle-aged man jumps under a tube train, and a teenage girl is killed in a hit-and-run, puzzlingly far from her home: two unrelated incidents which occupy DCI Bill Slider and his team during a slack period. But links to a cold case create doubts as to whether they are indeed unrelated.
» Have you read this book? We'd like to know what you think about it - write a review about Third Bill Slider Omnibus book by Cynthia Harrod-Eagles and you'll earn 50c in Boomerang Bucks loyalty dollars (you must be a member - it's free to sign up!)
Author Biography - Cynthia Harrod-Eagles
Cynthia Harrod-Eagles is the author of the contemporary Bill Slider Mystery series as well as the Morland Dynasty novels. Her passions are music, wine, horses, architecture and the English countryside.
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"The Young and the Restless" airs Weekdays on CBS. Weeknights on Pop TV. Anytime on CBS.com or the CBS app on Android and iOS enabled devices.
The Young and the RestlessALL THINGS RELATED
The Young and the Restless
Billy Miller/Michael Muhney: 'Y&R's' Cast & Crew Provide Video Tributes To Departing Male Stars
Monday, December 23, 2013 2:29 PM EDT
Billy Miller: 'I Thought I'd Be Fired Every Day'
Saturday, December 21, 2013 2:46 PM EDT
One More Piece of the Post-SOAPnet Puzzle Revealed: 'Veronica Mars' Joins Pivot Lineup
Saturday, December 21, 2013 7:10 AM EDT
Celeb Wedding Planner to Help 'Y&R' Characters Get Hitched!
Friday, December 20, 2013 4:31 PM EDT
'Y&R' and 'GH' Stars Address Michael Muhney Firing Rumors
Friday, December 20, 2013 4:24 PM EDT
Ratings: All Soaps Down in Women 18-49 Viewers
Friday, December 20, 2013 2:43 AM EDT
The Muhney Exit Interview: 'CBS and Sony Want To Give Adam A Break For 3-6 months and Then They'll Bring Him Back With A Different Actor'
Wednesday, December 18, 2013 7:45 PM EDT
Michael Muhney Exiting 'The Young and the Restless'; Last Film Date/Airdate Coincides With Billy Miller's
Wednesday, December 18, 2013 10:56 AM EDT
Longtime 'Y&R' Castmember Doug Davidson Discusses Soap's Spectacular 25 Year Streak as TV's Number One Rated Daytime Drama!
Monday, December 16, 2013 8:43 PM EDT
'Y&R's' Greg Rikaart Planning Meet and Greet for Oklahoma Fans!
Monday, December 16, 2013 4:11 PM EDT


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2006 Toyota Sienna LE 7 Passenger. Very nice one owner van with no accidents. 3.3L V6 with 174k miles, but don't let the miles scare you, this van is very clean and runs and drives great!!! AM/FM/CD player, power sliding door, rear spoiler, alloy wheels, power driver's seat, plus much more! This van i...
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Toyota Pickup - $1950 (St Cloud)
1990 Toyota Pickup for sale has 165,000 miles on it and needs a clutch. Location: St Cloud it`s NOT ok to contact this poster with services or other commercial interests
Year: 1950, Make: Toyota


text:
- Tickets >
- Concerts Tickets >
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University Symphony Tickets
Get ready for University Symphony, all the way live. University Symphony is playing this year in many cities . Buy premium University Symphony tickets and experience the thrill of a live concert with University Symphony at affordable prices.
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Pats Wanted To Trade Up?
By: Ian Logue
According to CNNSI.com the Patriots apparently tried to trade up to the fifth spot, with the intent to take linebacker Vernon Gholston who was selected by the Jets with the 6th overall selection but were turned down by the Kansas City Chiefs.
The NFL Network reported that it came down to between the Patriots and the Saints, who reportedly offered the Chiefs their 1st round pick for this year (No. 10, which ended up going to New England), next year's first round pick, and this year's 2nd round pick (No. 40) in order to move up to five so they could take LSU defensive tackle Glenn Dorsey.
That was a high price to move up to that spot, so it comes as no surprise that New England stayed out of the bidding. Even with that good of an offer Kansas City didn't bite anyway, and held onto that selection and took Dorsey themselves.
CREDIT: Thanks to messageboard user 'Section 103' for pointing this article out.
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I watched while the server took their lunch orders. Reluctant, they pulled away, to merely pick up again after she left. Staring at how simple it was for them to snub the crowded room, eyes gazing, cocooned in a makeshift world of self-made bliss. I strained to hear their conversation above the haze of the crowd's buzzing and only garnered small snips of their cozy happy whispering.
Horror struck when Ricardo took her hand to kiss while placing a ring on her finger. Its brilliance burned in the late afternoon light while scorching my soul. She received the gesture with an endearing smile and a long hard kiss on his full lips.
A bone deep ache over took me while the crowd cheered for them. I doubled over in real physical pain. I wanted to scream gazing at them and their open display of affection, while a sad dream hung
on my mind.
I remembered he held me once body, mind, spirit and soul. I gave Ricardo all of me; then he moved on with his life. I call to mind a vow once holy, a union once shared, but this picture of life anew made it void. Now it's a shadow of what once existed, I'm left to muse over a life once full of love now lost. The incident crossed my awareness and I remembered for the first time.
My world changed on a bright sunny day. The day he proposed, we sat at our table here near the window inside the café. He surprised me going to one knee while he held up
open a small black box. I had on idea he would propose to me. Sudden without warning, a car crashed through the building killing me instantly. I took the brunt of the impact saving Ricardo's
life. He spent a year of his life in a coma and another remembering how to walk.
Gripped with this truth, I'm no longer Ricardo's focus; he's found another to fulfill his dreams, his life and his bed. I had become a distance memory, a whisper in the breeze, a lost soul that hung back. I stayed where all our hopes and dreams began, where our bright future started and where my life ended.
I've stayed in this spot at the table by the window for four years waiting for Ricardo to return. I held on to wants and desires that he can never meet. I've stayed here because I'm a lost soul, a spirit still in love with the living.
I once had the love of a man who loved me. My love for him lingered, hopeful, but watching Ricardo with this woman and their love for each other. I realized there's no need for me. I drifted over to the loving couple, watching them this close I discern that I could never give him what he needed. I'm just a lost soul, now glad to have loved. I planted a soft kiss on Ricardo's cheek. He smiled and I believe it's for me.
It's right for me to move on, to fade into the eternal bliss. I looked to the light so bright near the window luring me. With a sigh, I drifted back realizing there's no longer a need to defy the strong pulling of infinite and glory that called upon me.
I turned to look one last time at Ricardo's happy face. It's genuine happiness I felt for him. Turning back toward the bright and mysterious radiance with the understanding there's no more time for me here. I took my first step into the bright light happy to enter the peaceful rest; bone weary from my time spent lingering.
© Copyright 2017 Ripples. All rights reserved.
Status: Finished
Genre: Flash Fiction
Hi, Ripples! This chapter was packed with emotion, and I am sad that she lost Ricardo, but I am happy she is choosing to go into the eternal bliss:) This is what made the chapter positive and uplifting. I would like to know what happens next with the bright light! Keep me updated?
Essay / Religion and Spirituality
Poem / Religion and Spirituality
Essay / Editorial and Opinion
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Come in to your nearest Firestone Complete Auto Care at 45-934 Kamehameha Hwy for all your car care needs. Learn more about our services, hours, and address below to get started.
At Firestone Complete Auto Care, we have been leading the automotive service industry since we began in 1926. If you think your car could have a problem, our professional teammates can perform a free courtesy check. We'll inspect lights, wipers, belts, and more. Plus, we're devoted to delivering the best quality service possible, all at reasonable prices and a quick wait time. Stop by our store today or schedule an appointment by phone or online.
After 90 years in the automotive industry, we've seen just about every car problem out there. At Firestone Complete Auto Care, we work to provide unparalleled auto repair and maintenance. Our products and services are covered by our Fixed Right Guarantee, meaning any auto service or repair is fixed correctly the first time. If not, we will re-perform the service with no additional charge. We understand that it's never the right time to fix your car, and that's why we constantly strive to make your total auto care experience stress-free.


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This is the first time a Woody Allen movie has looked interesting, maybe ever for me
Woody Allen's newest film, Cafe Society will open the Cannes Film Festival this year and make its North American debut in Seattle. The romantic comedy is Allen's 47th feature film and stars Kristen Stewart, Jesse Eisenberg, Steve Carell, Parker Posey and Blake Lively. In the film, a screenwriter living in the NY slums is captivated by Hollywood in the 30's
"Café Society" will be released by Amazon to theaters in the summer and will be released on Amazon Prime later in the year.
May 10, 2016 at 4:51 pm
This is the first time a Woody Allen movie has looked interesting, maybe ever for me
Toronto's Raunchy Sketch Duo 'Cheap Smokes' Go Beyond the Trailer Park
Patton Oswalt Teaming Up with Chicago's Ian Abramson to Create Modern Vaudville
Brooklyn Punk Rock Comedy Show Declares: The Future is F*cking Female
Latino Comedy Studio Mas Mejor Celebrates a Strong First Year With Fred Armisen
Daman Wayans Jr. Signs on For Seth Rogen's 'Singularity' Pilot
Remembering Alan Colmes, Radio and TV Host, and Stand Up Comic
Toronto's Raunchy Sketch Duo 'Cheap Smokes' Go Beyond the Trailer Park
Brooklyn Punk Rock Comedy Show Declares: The Future is F*cking Female
60% Of Americans Can't Name Any Of The Best Picture Nominees
The IBang Readers Vote for The Best of Everything in Comedy in 2016
The Comedians Call It! 40 Great Comics Tell Us Who Will Be the Next Big Thing in 2017
The Award for Remarkable Achievements of Exceptional Noteworthiness for Unrelated Things in Comedy
The Ten Best Comedy Specials of 2016! Vote for Your Favorite
The Catty "Everyone is Gossiping About You Behind Your Back" Awards
Finding comedy in everything and everything in comedy.
interrobang, in·ter·ro·bang [in-ter-uh-bang] ‽ (often represented by ?! / !?), is a nonstandard punctuation designed to combine the question mark (?) and the exclamation point (!), indicating a mixture of query and interjection, as after a rhetorical question.
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The human red blood cell has a uniquely developed membrane, which survives cellular deformations and shear stresses not encountered by most other cell types in the body. This membrane integrity and flexibility results from a two-dimensional protein network (membrane skeleton) on the cytoplasmic face of the membrane, which is comprised primarily of spectrin tetramers that crosslink short actin filaments. However, key structure-function features of spectrin tetramers and the spectrin self-assembly process are poorly understood. Equally important is the fact that the mechanisms by which hereditary hemolytic anemia mutations disrupt spectrin assembly and structure are in most cases inferred with little or no real supporting experimental data. The broad, long range goal of this project is to develop a detailed understanding of the mechanism of spectrin self-assembly into heterodimers and tetramers and determine how specific HE and HPP mutations perturb these critical molecular interactions, resulting in red cell membrane destabilization. Several hypotheses will be tested in these studies. The first hypothesis is that most HE mutations in ?-spectrin that are substantial distances from the tetramer site destabilize membranes by affecting the close?open dimer equilibrium. The second hypothesis is that tetramer assembly is substantially more complex than current three helix models suggest, with important contributions from Mg2+, terminal non-homologous ? and ? sequences, and possibly other co-factors including phosphorylation. The third hypothesis is that the weak lateral associations outside the dimer nucleation site are relatively non-specific, but they make critical contributions to the molecular properties of spectrin.
The Specific Aims of the current proposal are: 1) determine how HE and HPP mutations affect tetramer assembly and destabilize red cell membranes;2) define structural and functional roles of non-homologous spectrin "tails" and cofactors on spectrin tetramerization;3) determine crystallographic structures of the spectrin tetramer site and interpret the effects of HE mutations on tetramer formation;and 4) determine inter-subunit docking and medium resolution structures of weak lateral ??? associations adjacent to the dimer initiation site.
These Aims will be achieved using: thermodynamic analyses such as isothermal titration, sedimentation equilibrium and other biophysical methods to characterize intermolecular interactions;chemical crosslinking and mass spectrometry to define distance constraints that can distinguish between alternative molecular docking and conformational models, and X-ray crystallography to determine high resolution structures of non-covalent spectrin complexes. Structures of heterodimer and tetramer binding site complexes and elucidation of wild type interaction thermodynamics will provide a reference for determining how specific HE and HPP mutations disrupt spectrin self-assembly and thereby destabilize cell membranes. It is anticipated these studies will provide a solid foundation for genetic counseling as well as potential future development of novel therapeutic treatments for specific HE and HPP mutations.
Hereditary hemolytic anemias are common diseases that disrupt human red cells, most frequently by affecting one of the spectrin self-assembly interactions. Our analyses of the structures and thermodynamic properties of the spectrin heterodimer and tetramer assembly sites and the effects of specific hemolytic anemia-associated mutations on these interactions should form a useful knowledge base for genetic counseling as well as potential future development of novel therapeutic treatments.
|Pesciotta, Esther N; Sriswasdi, Sira; Tang, Hsin-Yao et al. (2014) Dysferlin and other non-red cell proteins accumulate in the red cell membrane of Diamond-Blackfan Anemia patients. PLoS One 9:e85504
|Sriswasdi, Sira; Harper, Sandra L; Tang, Hsin-Yao et al. (2014) Probing large conformational rearrangements in wild-type and mutant spectrin using structural mass spectrometry. Proc Natl Acad Sci U S A 111:1801-6
|Sriswasdi, Sira; Harper, Sandra L; Tang, Hsin-Yao et al. (2014) Enhanced identification of zero-length chemical cross-links using label-free quantitation and high-resolution fragment ion spectra. J Proteome Res 13:898-914
|Harper, Sandra L; Sriswasdi, Sira; Tang, Hsin-Yao et al. (2013) The common hereditary elliptocytosis-associated *-spectrin L260P mutation perturbs erythrocyte membranes by stabilizing spectrin in the closed dimer conformation. Blood 122:3045-53
|Swift, Joe; Ivanovska, Irena L; Buxboim, Amnon et al. (2013) Nuclear lamin-A scales with tissue stiffness and enhances matrix-directed differentiation. Science 341:1240104
|Bhattacharjee, Souvik; Stahelin, Robert V; Speicher, Kaye D et al. (2012) Endoplasmic reticulum PI(3)P lipid binding targets malaria proteins to the host cell. Cell 148:201-12
|Fong, Karen P; Barry, Colin; Tran, Anh N et al. (2011) Deciphering the human platelet sheddome. Blood 117:e15-26
|Krieger, Christine C; An, Xiuli; Tang, Hsin-Yao et al. (2011) Cysteine shotgun-mass spectrometry (CS-MS) reveals dynamic sequence of protein structure changes within mutant and stressed cells. Proc Natl Acad Sci U S A 108:8269-74
|Harper, Sandra; Speicher, David W (2011) Purification of proteins fused to glutathione S-transferase. Methods Mol Biol 681:259-80
|Osborne, Andrew R; Speicher, Kaye D; Tamez, Pamela A et al. (2010) The host targeting motif in exported Plasmodium proteins is cleaved in the parasite endoplasmic reticulum. Mol Biochem Parasitol 171:25-31
Showing the most recent 10 out of 35 publications