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Faculty & Research
Faculty Profile
Brian Calvi
IU Affiliations
Medical and Molecular Genetics, IU School of Medicine
Medical Sciences
- Contact Information
- Contact Brian Calvi by bcalvi [at] indiana [dot] edu
- By telephone: 812-855-5450
- Program
- Genome, Cell & Developmental Biology
- Research Areas
- Chromatin, Chromosomes, and Genome Integrity
- Developmental Mechanisms and Regulation in Eukaryotic Systems
- Eukaryotic Cell Biology, Cytoskeleton and Signaling
- Education
Ph.D., Harvard University, 1993
Postdoctoral Fellow, Carnegie Insitution of Washington, 1993-1998
- Awards
American Cancer Society Research Scholar
Research Description
It is critical to discover the mechanisms of normal cell cycle regulation if we are to fully understand what goes awry in cancer cells. Genomic DNA must be fully and accurately replicated and then segregated into two daughter cells when cells divide. DNA replication that is uncoordinated from cell division causes "replication stress" and DNA damage, which is sensed and corrected by cell cycle checkpoints. Defects in both DNA replication and cell cycle checkpoints lead to high rates of DNA mutation (genome instability) and cause cancer. There have been major advances in understanding the molecular mechanisms that regulate DNA replication, the responses to replication stress, and how defects in these processes lead to cancer. Yet, there are many variations on the canonical cell cycle and checkpoint themes during development that remain little understood. Defining these themes and variations is necessary to fully understand how cell division and development are normally coordinated, and how errors in these molecular mechanisms in different tissue types cause cancer.
The research in my laboratory focuses on defining the molecular mechanisms that regulate DNA replication and cell cycle checkpoints during development. We have primarily used Drosophila melanogaster (fruit fly) as a model system. We have also worked with human cells in culture, both in my lab and as collaborations, to determine whether the mechanisms we have defined in flies are operative in humans. We have discovered new aspects of DNA replication and cell cycle checkpoint regulation in development.
Specific subtopics:
- Variant polyploid cell cycles in development and cancer.
- Cell cycle regulation of DNA replication and genome stability.
- Cell cycle and chromatin regulation of apoptosis.
Select Publications
- Qi, S., and Calvi, B.R. (2016) Different cell cycle modifications repress apoptosis at different steps independent of developmental signaling in Drosophila. Mol. Biol. Cell, 10.1091/mbc.E16-03-0139 [article]
- Paranjape, N, and Calvi, BR. (2016) The histone variant H3.3 is enriched at Drosophila amplicon origins but does not bookmark them for pre-RC assembly or activation. Genes Genomes and Genetics (G3), 10.1534/g3.116.028068. [article]
- Chen, S., Stout, J. R., Dharmaiah, S., Yde,S., Calvi,B.R. and Walczak, C.E. (2016) The Kinesin-14 HSET Contributes to Genomic Integrity in Polyploid Cell Division (Mol. Biol. Cell, in press. [article]
- Zhang B, Rotelli M, Dixon M, Calvi BR. (2015). The function of Drosophila p53 isoforms in apoptosis. Cell Death Differ. doi: 10.1038/cdd.2015.40
- Liu J, Zimmer K, Rusch DB, Paranjape N, Podicheti R, Tang H, Calvi BR. (2015). DNA sequence templates adjacent nucleosome and ORC sites at gene amplification origins in Drosophila. Nucleic Acids Res. gkv766
- Zhang, B., Mehrotra, S., Ng, W. L., and Calvi, B.R. (2014) Low levels of p53 protein and chromatin silencing of p53 target genes repress apoptosis in Drosophila endocycling cells. PLoS Genetics, Sept.
Hassel, C., Zhang, B., Dixon, M., and Calvi, B.R. (2014) Induction of endocycles represses apoptosis independent of differentiation and predisposes cells to genome instability. Development 141:112-123.
- Calvi BR. (2014) HBO1:JADE1 at the cell cycle chromatin crossroads. Cell Cycle 2014; 13:15, 2322–2322. (News and Views).
Calvi, B.R. (2013) Making Big Cells: One size does not fit all. Proceedings of the National Academy of Sciences, 110 (24) 9621-9622 (invited commentary).
- McConnell, K., Dixon, M., and Calvi, B.R. (2012) The histone acetyltransferases CBP and Chameau integrate developmental and DNA replication programs in Drosophila ovarian follicle cells. Development, 139: 3880-3890. PMD 22951641. (featured by an "In this issue" article)
- Liu, J., McConnell, K., Dixon, M. and Calvi, B.R. (2011) Analysis of model replication origins in Drosophila reveals new aspects of the chromatin landscape and its relationship to origin activity and the pre-RC. Mol. Biol. Cell. 23(1): 200-212 PMID:22049023.
- Maqbool SB, Mehrotra S, Kolpakas A, Durden C, Zhang B, Zhong H, Calvi BR. (2010) Dampened activity of E2F1-DP and Myb-MuvB transcription factors in Drosophila endocycling cells. J Cell Sci. 123: 4095-4106. PMID: 21045111
- Mehrotra, S., S. B. Maqbool, A. Kolpakas, K. Murnen and B.R. Calvi. (2008) Endocycling cells do not apoptose in response to DNA re-replication genotoxic stress. Genes & Development 22:3158-3171. [cover article]
- Clark et al. (2007). Evolution of genes and genomes on the Drosophila phylogeny. Nature, 450:203-218.
- Calvi, BR, Byrnes, BA, and Kolpakas, AJ. (2007) Conservation of epigenetic regulation, ORC binding, and developmental timing of DNA replication origins in the genus Drosophila. Genetics 177:1291-1301.
- White, A.E., Leslie, M.E., Calvi, B.R., Marzluff, W.F., and Duronio,R.J. (2007) Cyclin E/CDK2 regulation of the Drosophila melanogaster histone locus body. Molecular Biology of the Cell 18(7), 2491-2502.
- Review: B.R. Calvi. (2006) Developmental Gene Amplification. In: DNA Replication and Human Disease. Cold Spring Harbor Laboratory Press. Melvin DePamphilis (ed.), pp 233-255.
- May, N.R., Thomer, M., Murnen, K.F., and Calvi, B.R. 2005 The origin binding protein Double parked, and its inhibitor Geminin, increase in response to replication stress. Journ. Cell Sci. 118:4207-4217.
- Bandura JL, Beall E., Bell M, Silver H, Botchan, M, and Calvi, BR (2005) humpty dumpty is required for developmental DNA amplification and cell proliferation in Drosophila. Current Biology 15: 755-759.
- Thomer, M., May, N.R., Aggarwal, B.D., Kwok, G., and Calvi, B.R. (2004). Drosophila double-parked is sufficient for re-replication during development and is regulated by Cyclin E / CDK2. Development 131(19): 4807-4818.
- Aggarwal, B.D. and Calvi, B.R. (2004). Chromatin regulates origin activity in Drosophila follicle cells. Nature 430: 372-376.
- Schwed GM, May NR, Pechersky Y, Calvi BR. (2002). Drosophila MCM6 is required for chorion gene amplification and genomic replication. Mol. Biol. of the Cell 13(2): 607-620.


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Jesse Gasparro, Associate Veterinarian
Dr. Jesse Gasparro grew up in New Jersey. He attended Ross University and finished his clinical year at the University of Pennsylvania. He is the youngest of five children. He knew that he wanted to be a veterinarian at a young age and has always worked toward that goal. He loves reading books and playing tennis. He is recently married and lives with his wife and two cats €œLily€ and €œFranklin€.
Why I do what I do: I have always loved working with and learning more about animals. I find animals to be incredibly fascinating and fun to work with. Veterinary medicine is very rewarding to me because I enjoy helping animals and through them being able to help the people who own and care for them.

subset: commoncrawl


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Obtaining Health Insurance: Individual vs. Group Plans
There are several ways in which an individual may obtain health insurance. And in the comment thread following my post - "Health Insurance Coverage Protects from Catastrophic Health Costs (!?!) - I promised to discuss various aspects of health insurance. Today we will discuss some fundamental differences between obtaining individual or group health insurance plans.
The most popular way to obtain insurance is through an employer who is in a position to negotiate a group plan (for two or more individuals) with a private health insurance company. Group insurance may also be obtained through a professional organization, an alumni association, or other membership type organization. Only fourteen states currently allow a self-employed individual to qualify as a group of one.
The idea behind a group plan is to spread the risk of claims over a wider selection of people, which would theoretically have a mix of healthy people who don't file claims and people with serious illness or childbirth. The insurance company sets the premium rates for the group to cover the average amount of claims, plus profit. It is important to note that each state regulates health insurance plans, except....
Some corporations and businesses may choose to have a health insurance company administrate a self-funded group plan in which the employer creates a fund to pay health claims and purchases stop-loss insurance to cover claims exceeding the resources in the fund. Self-funded group plans were made available under Employee Retirement Income Security Act (ERISA) and are not subject to state regulations. If one insured person in the group suddenly experiences expensive health claims (such as is associated with MS), premiums for all group members would be adjusted (raised) the following year to cover the increased expense. At times, employees might not even know that their company's health benefits are self-funded.
Another option is to purchase a policy on the individual health insurance market whose plans were originally designed to provide insurance to unemployed or self-employed persons not covered under an employer's plan. Individual health policies are often more expensive and offer fewer benefits, but are portable and guaranteed renewable in most circumstances. Each state has rules governing individual policies. It's important to note that persons applying for individual policies will need to go through the underwriting process which determines the risk to the insurance company and makes the applicant subject to adverse selection.
For individuals deemed uninsurable by traditional underwriters, thirty-three states have High-Risk Pool guaranteed-issue plans. Virginia is not one of those states. In other states, such as Ohio and Idaho, premiums for high-risk plans are limited to 2.5 of regular underwritten policy rates. If that were the case in Virginia, my underwritten policy (which was obtained when I was considered healthy and insurable) would cost $9450 annually instead of $3780 as it does now. That's a big jump in premium costs.
There are important differences between group and individual plans when it comes to applying for coverage, the most significant difference being exclusions on pre-existing conditions found in a person's medical history, which for MS automatically categorizes us as high-risk individuals and uninsurable. People with pre-existing conditions may be unable to find affordable health insurance or any health insurance at all if they are unable to pass the underwriting process.
One the other hand, group plans cannot single out high-risk individuals; nor can they deny them health coverage. All individuals are covered regardless of existing health problems, and the costs of high-risk individuals become spread over the total cost of the group.
A third way, which I will not go into just now, is through government programs, such as Medicare, Medicaid, the Veterans Administration, and the Federal Employees Health Benefit Plan (FEHBP).
In a future post, I will discuss the differences between benefits found in group vs. individual health insurance policies. This is where it gets really interesting.
Until then, stay well and be healthy.
Lisa Emrich is author of the blog Brass and Ivory: Life with MS and RA and founder of the Carnival of MS Bloggers.


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Known to progressively blend audio and visual elements in his work, Woodkid takes live performance to another level by incorporating 4D components. Taking to the stage of Grand Journal de Canal+ with an orchestra, the French musician performed "Run Boy Run" from The Golden Age album, while 4D visual graphics combined with motion capture of the performance itself elevated the four-minute showcase. Enjoy the clip above and head to iTunes to purchase The Golden Age.


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Veterans take time to bond and relax at Camp Bliss in Walker including (from left) Larry Quade, Darby Nundahl, Jimmy Krejce, Jimmy Johnson and Tony Christensen.
In this picture from last fall Tucker is getting ready to take his dad Darby and brother Luke for a ride in Tucker's Model A Doodlebug with airplane tires. This was Tucker's first vehicle.
The item which was stolen from a Lakeside Cemetery grave.
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This is the previous residence of the actors. There current home is also featured on this site.
Melissa Gilbert & Bruce Boxleitner's House (former)
By tlp333 @ 2007-12-14 22:16:56
Links: en.wikipedia.org
Nearby Maps (50 km): 11,432
@ 2007-12-14 22:36:30
I believe even Pa would be impressed with" half pints" digs..


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There is more information than ever before at the point of purchase for a hotel stay. With ratings, reviews, price, brand, and TripAdvisor rank, consumers can get a full picture of the value of a hotel as compared to others ...Read More »
Category Archives: Social MediaFeed Subscription
User-Generated Marketing Campaigns Engage Travelers
In the days of film cameras and slide projectors, having to (painfully) sit through the vacation photos of family and friends was a common occurrence. But times have certainly changed. With the social media explosion, anyone can easily share photos, ...Read More »
Radisson Blu Launches New Blog
MINNEAPOLIS AND BRUSSELS—Radisson Blu today announced the launch of its newly designed travel magazine-style blog and an innovative way for like-minded travelers to share tips and knowledge about the destinations that surround their hotels. In a contest titled Social Eyes, ...Read More »
Using Instagram to Acquire More Customers
Instagram is one of the fastest growing social media platforms. The popular photo-sharing app amassed 150 million monthly users in about three years—two years faster than Facebook and half the time of Twitter, according to L2 Think Tank. And now, ...Read More »
Loews Atlanta Expands Social Media Reach
Goals should not only be met, stresses Drew Mailloux, but be surpassed. As the marketing manager of the 414-room Loews Atlanta Hotel, he saw the property hit the 2,500 "like" mark on Facebook in January 2013 and made plans to ...Read More »
Perch App Helps Hotels Track Competitors
Social media offers hotel owners and managers a wealth of information at their fingertips, but being able to access it all can be a challenge. With so many outlets that allow guests to share pictures and thoughts about a hotel—Facebook, ...Read More »


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Lot 23: A pair of silver twin branch three light
Fine Jewellery, Silver and Objects of Vertu
by Dreweatts & Bloomsbury
November 28, 2012
London, United KingdomLive Auction
Looking for the realized and estimated price?
Description: A pair of silver twin branch three light candelabra by Roberts & Belk Ltd, Sheffield 1975, shaped square with shell angles, with detachable sconces to the reel capitals with drip pans, scroll branches, multiknop stems, the moulded bases with shells at the angles, 39cm (15 1/4in) high, the branches 1713g (55.05 oz), the bases loaded
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Mirror Mirror
- Record Label: Domino
- Release Date: Jun 13, 2011
- Summary: The Scottish rock band's first album since 2008's The Gift was produced by JD Twitch.
- Record Label: Domino
- Genre(s): Pop/Rock, Alternative/Indie Rock, Alternative Pop/Rock
- More Details and Credits »
Score distribution:
Positive: 12 out of 20
Mixed: 8 out of 20
Negative: 0 out of 20
Jun 14, 2011Mirror Mirror is a raw, nocturnal and very northern record, and one that's nailed its bleeding, hedonistic colours high up the musical mast.
MojoJun 24, 2011The resulting record is one that softens with repeated listens, even if it's so full of bad juju you may initially feel compelled to burn it at the stake. [Jul 29011, p.112]
Dec 9, 2011Mirror Mirror isn't the kind of record that will bowl you over right away, but as you listen, the barely contained drama and violence of the performances, the bloody hooks each song contains, and the inspired craft of the arrangements will draw you in and knock you out.
Jun 24, 2011The weird miracle is how natural singers Scott Paterson and Adele Bethel sound harmonizing (well, singing together) over subdermal synth buzz.
Jul 15, 2011In a way, the clear stylistic changes here put a spotlight on how diverse the group's discography really is. Just when you think you know somebody....
Jul 6, 2011Damned if they do and damned if they don't, it seems, but never sounding damned enough.
Jun 14, 2011Reminders of the past are pleasant, but at the end of the day, you'll be choosing Power, Corruption & Lies or Songs of Faith and Distortion over Sons & Daughters' Mirror, Mirror.
Score distribution:
Positive: 0 out of
Mixed: 0 out of
Negative: 0 out of
|Metal Box [Super Deluxe Edition] - Public Image Ltd.
|The Early Years 1967-1972 [Box Set] - Pink Floyd
|Singles: The Definitive 45's Collection - Sun Ra
|Skeleton Tree - Nick Cave & the Bad Seeds
|Live at the Whisky a Go Go: The Complete Recordings - Otis Redding
|Box [Box Set] - Gas
|The 1966 Live Recordings [Box Set] - Bob Dylan
|Who Can I Be Now? (1974-1976) [Box Set] - David Bowie
|You Want It Darker - Leonard Cohen
|We Got It From Here...Thank You 4 Your Service - A Tribe Called Quest
|A Seat at the Table - Solange
|Fuzzy Logic [20th Anniversary Deluxe Edition] - Super Furry Animals
|American Band - Drive-By Truckers
|Black America Again - Common
|The Complete BBC Sessions [Remastered] - Led Zeppelin
|Run the Jewels 3 - Run the Jewels
|My Woman - Angel Olsen
|Kodama - Alcest
|Elwan - Tinariwen
|Live at the Hollywood Bowl - The Beatles


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Comment Re:Figured it'd happen (Score 1) 507
These aren't your everyday jailbreakers, they're the people that found the exploits that allow jailbreaking. There's no indication that they're banning everyday jailbreakers, or AFAIK that they know which devices have been jailbroken. It seems all they did is search though apple ids for some dev team handles.


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Hotfrog Philippines provides information regarding Denso / Mufflerhaus in Cebu City Cebu. Denso / Mufflerhaus is located at M J Cuenco Avenue, Cebu City Cebu 6000 and provides Retail services. Contact them on (032) 233 1880.
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有限元方法: 精度及其改善
Elsevier, 2006 - Mathematics - 320 pages
Distributed by Elsevier Science on behalf of Science Press.
This book discusses the accuracy of various finite element approximations and how to improve them, with the help of extrapolations and super convergence's post-processing technique. The discussion is based on asymptotic expansions for finite elements and finally reduces to the technique of integration by parts, embedding theorems and norm equivalence lemmas. The book is also devoted to explaining the origin of theorems.
* Masterly exposition of the accuracy and improvement of finite element methods, highlighting the postprocessing
* Emphasis on understanding of higher knowledge
* Accessible to students, engaging for experts and professionals
* Written by leading Chinese mathematicians, available internationally for the first time
What people are saying - Write a review
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Selected pages
Eulers Algorithm and Finite Element Method
Function Spaces and Norm Equivalence Lemmas
From K to Eigenvalue Computation of PDEs
Appendix 1
Appendix 2
Appendix 3
Appendix 4
First Part Bibliography
Expansion of Integrals on Rectangular Elements
Expansion of Integrals on Triangle Elements
Quasisuperconvergence and Quasiexpansion
Second Part Bibliography
Common terms and phrases
adjacent elements ah(u BH lemma bilinear interpolation boundary broken-line common edge Consider the functional construct postprocessing interpolation convergence defined derivatives direct computation shows domain dxdy ECHL edge-integral eigenfunction EQ\ot error estimate error expansion Example expansion lemma extrapolation finite difference method finite element interpolation finite element method finite element solution finite element space fishbone four small elements function space fundamental formula G Vh give a proof gives the lemma Green formula h2 f Hq(Q interpolation function inverse inequality isosceles right triangle L2-norm Legendre polynomial Lin Q line integrals mixed element space nonconforming elements nonconforming error norm equivalence lemma piecewise Poisson equation polygon polynomial Proof Let prove quasi-superconvergence Ratio(2 real superconvergence reference element right triangle mesh rotated bilinear element satisfies scaling argument gives Schwartz inequality Sobolev embedding theorem Suppose that Vh uniform convergence uniform rectangular mesh vector vertices Vh,o weak equation wxvxdxdy zero


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Giant Inflatable Beach Ball Need some giant garden games for the children when the sun comes out? This is not an ordinary beach ball, it is much larger than normal beachballs and inflates to a massive 10 feet tall! Outdoor games are really good for keeping the kids out of trouble during the summer holidays, and inflatable toys are always great for a childrens pool party or a day out by the seaside. Picture this, you're on your holidays on the coast with the family and you've found a quiet part of the beach with no German beach towels in sight, and it's time for some beach games! If you're after some beach accessories or outdoor toys then your kids will love to play with one of the largets inflatable beach balls!
Catalogue Number: 503-0199
- Giant inflatable beachball
- Inflates to 10'
- Weight when deflated: 6lbs
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Product Details
Product specifications
Product Height
50.0 Centimetre
Product Width
38.0 Centimetre
Product Depth
9.5 Centimetre
Product Weight
6400.0 Gram
Key Information
Sand/water toy
Age Range
6 years to 24 years
Appropriate Age Warning


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I have the same feeling about the euro onscreen score. It's terrible. So here is my approach. The seconds would count in the green ring around the minutes. The scorer could slide to the side shortly after the goal was scored.
And I know Denmark doesn't wear blue shirts (the goal keeper does), but it just looks cooler then red. ;)
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Arthur Nazaryan Photographer
Arthur Nazaryan taught himself photography while studying philosophy at the State University of New York, Stony Brook. His photographs have appeared in The New York Times, BBC, and Huffington Post World News. His coverage of the "Red Shirt" conflict in Bangkok was featured in Eunice Lau's documentary, Hero. Arthur's work focuses on humanitarian issues in Southeast Asia and East Africa, as well as refugee communities in the United States. He is currently working on contract for Clear Path International in Thailand and Myanmar. Click here to see more of his work.


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"Flat Clyde", Knowing how tired you are after all the dancing and cavorting with
your mostly dead cronies, can I now spell Uzo--Uzu? Thanx for the info, old
firstname.lastname@example.com wrote:
> << They quoted Tony Avent as
> using the Uzu spelling and said that is why they thought is was correct. >>
> I would always go with the advice of Antoine "Tony" d'Avent. As I recall,
> although I am a little bit tired after having jitterbugged at my 80th High
> School Reunion, Wolfram Georg Schmid spells it "Uzo." Person who knows is S.
> N. He speaks Japanese.
> Clyde Crockett z5
> ---------------------------------------------------------------------
> To sign-off this list, send email to firstname.lastname@example.com with the
> message text UNSUBSCRIBE HOSTA-OPEN
Jill, Mike, Danielle, and Jolie
Miller's Perennials and Llama Criation Farm
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Oanda back to basics as tough rules hit retail market
Retail foreign exchange brokers are struggling to find ways to survive in a harsh new regulatory environment, with some opting to simply exit the market altogether. Margin FX trading provider Oanda's approach is to shift its focus away from expansion plans, such as its recent foray into the institutional space, and back to its core clients. The Toronto-based firm has offices in Singapore, Tokyo,...
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Tag Archives: rx-7
MINICARS: 2013 Hot Wheels X JNC Treasure Hunt Mazda RX-7
This week's QotW was about the hardest JNCs to find. Here's another one. We are proud to announce our latest collab with Hot Wheels, the 2013 Treasure Hunt Mazda RX-7!! You read that right. JNC has entered the rarefied ranks of … Continue reading
EVENTS: Shokuji J-Tin, Part 01 – Wangan Style
Last year a fantastic new show called the Bayline Gathering emerged on the NorCal scene. It brought out some of the best cars the region had to offer and filled a void that desperately needed filling. Last month, the organizers were … Continue reading
MOTORSPORT: Mazda is the official car of the SCCA
Mazda often boasts that on any given weekend, there are more Mazdas on racetracks than any other marque. As such, it was already the de facto car of the SCCA, but now it's officially official. Mazda is the car of the Sports … Continue reading
QotW: What's the most impressive JNC restoration job you've seen?
Since it's Easter this weekend, let's talk about resurrection. It wasn't too long ago that Japanese cars were considered disposable and unworthy of restoration. In our opinion, that only makes you crazy JNCers even more heroic when you put your blood, … Continue reading
EVENTS: 2013 Nostalgic2Days, Part 03
We begin Part 03 of our Nostalgic2Days coverage with four generations of beautiful 'Ladies. There's the Wangan wedge Z31, disco club S130, world beating S30, and the pre-Z roadster spanning two decades of sporting Nissans.
EVENTS: 2013 JCCA New Year Meeting, Part 03
We sure feasted our eyes on beautiful examples of Nihon steel in Parts 01 and 02 of our 2013 New Year Meeting coverage. The real show, however, is in the spectator parking area, which is packed full of shakotan sleds … Continue reading
EVENTS: Classic Japan 2012, Part 01 — Rock Stock
Today's coverage of the 2012 Classic Japan comes courtesy of Australian contributor Adam Laws. Enjoy! —Dan November 25th saw the second running of Classic Japan in Melbourne, Australia, a show celebrating 25-plus-year-old J-tin, run by the Toyota Car Club of Australia (VIC), in conjunction … Continue reading
BOOKS: The Stainless Steel Carrot, An Auto Racing Odyssey — Revisited
John Morton has lived a life most of us can only dream of. The legendary driver has had a storied career piloting everything from Shelby Cobras to Porsche Le Mans Prototypes. Of course, the reason Nissan nuts line up for … Continue reading
QotW: What's the best nostalgic for the Pacific Northwest?
I've just spent the Thanksgiving holiday driving through rural Oregon, along the Columbia Gorge, up to Portland and ultimately Seattle. It rained, heavily, non-stop the entire 900 miles. Everything from minivans to tractor trailers threw up walls of mist so … Continue reading
FRIDAY VIDEO: Initial D Fifth Stage, Episode 01 – Encounter of Destiny
Admit it, you've been waiting for this, ever since Fifth Stage rumors surfaced months ago. There's no shame in being a fan of Initial D. After all, it features some of our favorite cars drifting through the mountains of Japan, and it can't … Continue reading
Mazda RX-7 reportedly returning in 2017
2017 will be an important year for Mazda's rotary engine, as it will mark 50 years since the revolutionary motor's debut in the 1967 Cosmo Sport. However, our mates at Australia's aptly named The Motor Report are, well, reporting that 2017 is … Continue reading
EVENTS: 2012 Japanese Classic Car Show, Part 09: Editors' Choice
It should be no surprise by now that the Japanese Classic Car Show continues to grow each year, but we still weren't quite prepared for just how much bigger and better it was for 2012. Let's recap some of the highlights … Continue reading
EVENTS: 2012 Formula D Car Show & Drifting Championships
Formula D isn't the kind of event we here at JNC normally cover, but in recent years stateside drifting has grown tremendously, and with that growth it has welcomed with open arms the nostalgics that made all this tail-sliding possible.
EVENTS: MazFest/SevenStock 2012: The Sevens
As the name implies, SevenStock was originally a gathering for Mazda's iconic sports car, the RX-7. Over the years it's evolved to include all rotaries, and this year they teamed up with MazFest to throw one giant celebration of all cars flying … Continue reading
EVENTS: 2012 Japanese Classic Car Show, Part 05: Sports Cars
You want Zs? You got Zs. We begin Part 05 of our 2012 JCCS coverage with the seminal Japanese sports car, the one that forever changed perceptions of what it meant to be "J-tin" and swept America by storm. Here … Continue reading
SevenStock Preview: JNC "Daytona" Shirt
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EVENTS: 2012 Japanese Classic Car Show, Part 01: Debuts
The 2012 Japanese Classic Car Show has come and gone, and this year's was the hottest one yet. We mean that literally, as it was an unseasonably scorching 100-plus degree day, rare even for SoCal in September, but that didn't … Continue reading
JCCS Preview: JDM Legends' 1:1 Hot Wheels Mazda RX-7
Our friends at JDM Legends have been hard at work on a project they plan to debut this Saturday at JCCS. As you can see from this teaser photo, it's a Mazda RX-7, but it ain't just any 7. When … Continue reading
The beautiful Box Art and history of Aoshima model kits
Step inside any Japanese hobby store and you're bound to be dazzled by both the beauty and abundance of Aoshima box art. Their highly detailed plastic model kits have been around for decades, and in many cases have done a … Continue reading
QotW: What diecast car should they make next?
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Should your preferred language not be available, contents will be displayed in English.
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Last modified On 11 March 2015
ClickShare is compatible with iOS devices such as iPads and iPhones. These devices can be connected to ClickShare either via the ClickShare App (which allows sharing of static documents such as PDF, jpeg or MS Office documents) or via the AirPlay Mirroring function included in CSC-1 firmware version 1.07 (December 2014) and above.
The ClickShare App provides a virtual button enabling you to share static content from your iPad, such as MS Office or pdf documents and jpeg images, as well as do annotations. The app can be downloaded from the Apple app store.
AirPlay Mirroring function included in CSC-1 firmware version 1.07 (December 2014) and above.
3059 Premiere Parkway Suite 400Duluth, GA 30097United States
3078 Prospect Park DriveRancho Cordova, CA 95670United States
28 Feb 2017
Consumer vs. medical-grade displays (1/4): A question of accuracy
01 Mar 2017 - 05 Mar 2017Bruno Kreisky-Platz 1 - AUSTRIA


text:
x = true;
(function() {
for each(let c in [0, x]) {
(arguments)[4] *= c
asserts js debug shell on JM tip with -m and -j at Assertion failed: LIR type error (start of writer pipeline): arg 1 of 'fmul' is 'int' which has type int32 (expected float64): 0 (../nanojit/LIR.cpp:2610)
A variant testcase asserts differently:
var c;
(function() {
for each(e in [0, 0]) {
(arguments)[1] *= c
Assertion failure: m != TT_INT32 || isInt32(*vp), at ../jstracer.cpp:3796
This affects tm-tip too.
Yuck. The problem is that the tracer expects arguments[n] to be undefined if |n| is out of range. In this case, it is _not_ undefined, it is NaN, because the interpreter did this:
arguments[4] = undefined * 0
You're right - it occurs on TM tip with -j. In the past, it used to assert at:
Assertion failed: ((unsigned)r)<8 (../nanojit/Nativei386.cpp:427)
Assertion failed: s0->isQuad() && s1->isQuad() (../nanojit/LIR.cpp:2182)
before morphing to the current form.
autoBisect shows this is probably related to bug 453730:
The first bad revision is:
changeset: 30020:c76558a87dd9
user: David Mandelin
date: Wed Jul 08 11:16:41 2009 -0700
summary: Bug 453730: trace JSOP_ARGUMENTS, r=gal
dvander and I talked this over, and we think all that it takes to fix this is to abort tracing a getelem with arguments (args[expr]) if the index is a constant that is out of range. The tracer already aborts if the index is a non-constant that is out of range, so this just makes things consistent.
ETA = patch up for review later today.
Created attachment 437988 [details] [diff] [review]
Adding bug 547299 as a dep because it needs to land on 1.9.2 before the patch for this bug can land there.
Comment on attachment 437988 [details] [diff] [review]
The patch looks good.
Please put newlines on the last line of the two test files.
(In reply to comment #7)
> Adding bug 547299 as a dep because it needs to land on 1.9.2 before the patch
> for this bug can land there.
That one's fixed in 126.96.36.199, please add a 1.9.2 patch for this bug (or request approval on the trunk patch if it applies)
Why did this just land on 1.9.2 without approval? This isn't a new policy, and I've said this before. All branch patches must have explicit approval before landing. blocking+ is not enough.
(In reply to comment #12)
> Why did this just land on 1.9.2 without approval? This isn't a new policy, and
> I've said this before. All branch patches must have explicit approval before
> landing. blocking+ is not enough.
It's set to blocking 126.96.36.199. I don't even know why am answering this nonsense.
Tracer has been long gone on trunk, marking verified.
A testcase for this bug was automatically identified at js/src/jit-test/tests/arguments/bug554670-1.js.


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Located at the corner of Bruce Rd 1 and Bruce Rd 6
Open 8:00 a.m. to dusk, 7 days/week
Featuring scooped cones of Chapman's Ice Cream and Tracey's Dairy Ice Cream (the size of cones is legendary!)
Offering old-world style and personal service, the Holyrood General Store stocks household staples as well as farm and garden supplies. It caters to the growing Mennonite population and horse and buggies are a common sight tied up along side the store. You know that spring has arrived when tables overflowing with beautiful flowers and plants are displayed for sale outside the store.
**Sammy is at this location**
While you are here:
Magazines and professional golfers alike have dubbed BlackHorse as one of the top new courses in Ontario and one of the best golf values in the province. It has been ranked as the best public course in Southwestern Ontario with the best greens! Come and play. See for yourself what's so spectacular about BlackHorse.
Huron-Kinloss' newest garden centre. Stop in for annuals, perennials, shrubs and vegetable plants. Custom potting services also available. Open Monday to Friday 10:00 a.m. to 7:00 p.m. and 10:00 a.m. to 5:00 p.m. on Saturday's and Sunday's.
Buy Local! Buy Fresh! From peas, jam and cut flowers to corn, peppers, and rhubarb, Kinloss Produce has sweet and delicious produce. Take home in-season fruit and veggies today. Located at 1404 Grey Ox Avenue (Concession 4) west of County Rd 1. Please respect their day of rest on Sunday (NSS). They are also closed on Tuesdays.


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Very Nice Soap
Verified Purchase
Very Nice Soap
This is a lovely scented soap and is very long lasting too. I have been using it everyday now for many weeks. One easy little trick to keep the soap lasting even longer is to push the underside of a plastic milk bottle lid into the underside of the soap. This keeps the soap off the counter top and lets it dry underneath.
Not being notified on changes of ingredients
Posted by 5757042611998439329 on Jan 08, 2017
The Company has changed the package design as well as the INGREDIENTS of this soap, making it less pure and simple like it used to. New ingredients for everyone's reference:- Sodium Palmate, Sodium Palm Kernelate, Water, Glycerin (Vegetable), Fragrance (Essential Oil Blend), Butyrospermum Parkii (Shea Butter), Sodium Gluconate, Palm Acid, Sodium Chloride, Palm Kernal Acid, Soy Milk, Iron Oxides (CI 77492), Titanium Dioxide (CI 77891), Iron Oxides (CI 77499), Boswellia Carterii Resin Extract, Commiphora Myrrha Extract, Honey Extract. Not gonna give high ratings whether or not it has the same benefits / extra goodies, since customers are not being notified on the changes, which in turns defied our right to know.
Very Nice Soap
This is a lovely scented soap and is very long lasting too. I have been using it everyday now for many weeks. One easy little trick to keep the soap lasting even longer is to push the underside of a plastic milk bottle lid into the underside of the soap. This keeps the soap off the counter top and lets it dry underneath.
Buy this soap if you have dry skin!!!
Posted by Reviewer2720611 on Jun 05, 2010
We tried this soap because of our cold CT winters and our aging (!!) dry skin, and there are just so many things to like about it. First, it completely changed our skin (and it's not like we had been using Dial or some other harsh commercial soap.) The smell is incredible, almost makes our whole bathroom smell good (it's a small bathroom). Didn't like Nubian's black one nearly as much - this one is the best - and iherb's price is also the best.
Love it!
Posted by Reviewer1483278 on Apr 30, 2010
My husband has sensitive skin. So I brought this soap for him. But now not just my husband love it, I looooove it ,too! It smells so good and it is so rich to use but so easy to rinse off. And it doesn't take much to soap up the whole body. It gives me a relaxing good mood with it's scent. Love it! Love it! It's on my re-order list from now on!
love this!
Posted by Reviewer2106073 on Aug 18, 2010
The smell of this soap is nice and makes our skin very soft. This is our second buy and we will continu to purchase. Make sure you don't get the foam in your eyes. It's very irritating.
Posted by Reviewer1621299 on Jul 07, 2010
I tried this cause of the reviews. I always have trouble with soaps, so was reluctant. It's good though! The smell is nice too. I would try other scents by this brand. Moisturizing and non-drying, makes you smell CLEAN.
Love the soap
Posted by Reviewer1818092 on May 21, 2010
I really like this product. It smells nice and doesn't make me itch like regular soap does. Will buy again!
If this is in stock - Buy it. You'll be glad you did
Posted by Reviewer1152715 on Apr 24, 2013
All of the soaps in this range are excellent, I recommend this if you have dry skin, the scent is really nice.
Posted by vafa33 on Feb 22, 2015
a bit strong smelling for me as i prefer fresh ones
shea butter
Posted by 4744493424708707935 on Apr 12, 2015
I liked the smell of soap . However, it makes the skin dry . I would recommend for dry skin Nubian Heritage- " Mango Butter Soap, Shea & Cocoa Butters"


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The Secret Techniques of Bonsai: A Guide to Starting, Raising, and Shaping Bonsai
Kodansha International, 2005 - Gardening - 111 pages
The Japanese art of bonsai is practiced worldwide, but while basic techniques have been more or less effectively taught, many of the more intriguing ones, as well as recently invented ones, have not. 'The secret techiniques of Bonsai' remedies this oversight with the thoughtful instruction of second and third generation experts. 'Secret teachings' is by the author of the groundbreaking 'Bonsai with american trees', one of the first books to unveil the secrets of the trade. This time, Masakuni Kawasumi II teams up with his son, Masakuni III, to offer not only the basics for creating perfect bonsai but secret techniques he has developed over years of careful work and observation. Masakuni III, the first qualified tree doctor for bonsai in Japan, adds his unique insights. Between them they offer over eighty years of experience. The techniques are simple and intuitive, yet have been developed only after decades of practice and perfection. Detailed information is provided to start, nurture, and shape bonsai. A number of secret techniques are introduced for beginners and experienced enthusiasts alike. The father-and-son team also delves into bonsai tool usage, another area of their expertise, giving the reader a clear sense of how to use specialized tools-or how to better use the garden and workshop tools they have at home. All these make this an invaluable book for beginners and experienced enthusiasts alike.
What people are saying - Write a review
We haven't found any reviews in the usual places.
Before Getting Started
Species and Styles of Bonsai
Starting a Bonsai
Jumpstarting Your Bonsai
A Last Word from the Tree Doctor
Other editions - View all
The Secret Techniques of Bonsai: A Guide to Starting, Raising, and Shaping ...
Masakuni Kawasumi, III
No preview available - 2013
Common terms and phrases
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Smock tops, print t-shirts, smart shirts and much more! Check out our collection of baby girls tops for all of her essentials, and some adorable occasionwear. Our extensive selection of baby girls tops is both cute and comfortable, and comes in a range of fun colors and prints that little girls will love.
RECALL NOTICE: Mini girls embellished shirt FIND OUT MORE
Was $28.00 Was $28.00 Was $28.00 Was $28.00


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Panda & Link Quantity: Can You Escape Panda's Jaws?
Everyone knows that Google have been throwing their weight around recently, the deindexing of high PR blog networks has caused havoc in the SEO community. Lots of people have been hit with messages from Google warning of unnatural linking activities – this message is normally followed by a nose dive in the SERPS. So, is it possible to rescue a penalized website? Lots of people seem to be saying it is.
Subscribe to my exclusive newsletter, and learn secret SEO tactics to boost your traffic»
Build more links!
It's still unclear as to whether these big tumbles in the SERPS are due to penalties imposed by Google, in fact just mass link loss (some people had thousands of links from these high PR networks remember). What is for sure is that if your website is ever going to make it to the top of the SERPS, you're going to need to build more links to it. Don't just sign up to one of the remaining high PR blog networks though, take some time to do it properly.
There are loads of places that you can get whitehat links from. Do some guest posts on related blogs in your niche, post some comments on related blogs, write some articles and put them on sites like Hugpage or Ezine – you really are spoilt for choice. Don't go building links using mass-automated tools, these will probably only do more harm than good in your recovery efforts.
Think about where you're building links to
One of the strange things about the loss of SERPS due to using blog networks is that entire websites haven't been hit – instead it appears only those web pages that were heavily linked have been hit. You might want to think about moving the content from the page you're trying to rank to a fresh page on your domain – you should find it a lot easier to rank. Don't use the same old blackhat methods though, get legitimate backlinks that won't cause you hassle in the future. Don't forget to put a 301 in place for your old page too – because it will still have a lot of backlinks pointing at it.
Linkbuilding best practices should be adhered to also – remember not to build too many links using anchor text, and definitely don't use the same anchor text for each and every link. Try to ensure that over 50% of your link profile is "naked" links – and not links that use anchor text, it just doesn't look natural. Another small tip that seems to be working for some people is to alter the meta data on the page(s) that have taken a tumble in the SERPS.
It's still early days and there's no way of knowing exactly how to reverse the effects of the latest Panda update, and the blog networks being deindexed. If you haven't already then now is definitely the time to knuckle down and start building only quality links, whilst publishing only high quality, totally unique content on your website.
When you're learning search engine optimization, you need to understand that the very first step is to create a website. If you're interested in starting your own blog, I have written a step-by-step guide that will show you how to start a successful blog for as little as $3.49 per month (this low price is guaranteed only through my link). You will also receive your own domain name for free ($15 value) by clicking on this link and purchasing at least 12 months of hosting with BlueHost. Keep in mind that if you're learning how to do seo, the first thing you need is your own self-hosted website. It will help you look more professional in front of your visitors, clients, companies, and everyone else, including search engines.
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Social bookmarking have worked really great for me and still it does work great ,when i am working on my own or my clients websites i always use mixture of article marketing, press releases and social bookmarking and it does work. I have ranked many of my own and my client`s website by using diverse links . Link diversity is the key


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NAI Daus Announces Strategic New Hire
CLEVELAND, May 11 NAI Daus is proud to announce a talented new member of its team of established brokers, Ms. Debbie Maggard. Maggard has more than two decades of commercial real estate experience and results.
"We are very happy to have Ms. Maggard join our team," said Robert Brehmer, managing partner of NAI Daus. "She brings a substantial amount of experience and expertise, which will help NAI Daus better serve our clients and help continue our success." He added, "We also recognize that now is a great time to expand our presence, and grow our market share."
Maggard's experience includes retail tenant/landlord representation, investment sales, industrial and office sales and leasing. She works with both local and national tenants. Her clients include: H&R Block, Pizza Hut, Best Buy, Curves, Verizon Wireless and PetSmart, to name a few.
Maggard has been in Commercial Real Estate since 1981. She is an active member of the International Council of Shopping Centers and her area of specialization is in the retail sector of commercial real estate. Maggard has a Bachelor of Science in Business Administration from Lake Erie College.
For more information, visit www.naidaus.com or call (216) 831-3310.
About NAI Daus
Founded in 1964, NAI Daus is the Cleveland office for NAI Global, the world's largest managed network of commercial real estate firms with more than 5,000 professionals serving 325 markets in 55 countries. NAI Daus is a full-service commercial real estate brokerage firm dedicated to strategically optimizing its clients' real estate assets. NAI Daus offers a diverse range of expert brokerage and property management services for the industrial, office, land and retail industries throughout Northeast Ohio. BPS Mngt, Inc. is a subsidiary of NAI Daus. NAI Daus clients include: American Greetings Corporation, Levin Furniture and Weyerhaeuser, to name a few. Recent awards include the Costar Power Broker Award, the NAIOP Investment Deal of the Year Award 2004, 2005 and 2006 and the NAI Chairman Award 2010. Professional affiliations include: Certified Commercial Investment Member (CCIM), Society of Industrial and Office Realtors (SIOR), Institute of Real Estate Management (IREM), Cleveland Area Board of Realtors (CABOR), International Council of Shopping Centers (ICSC), CoreNet Global (Core Net) and Commercial Real Estate Women, Inc. Cleveland (CREW).
Available Topic Expert(s): For information on the listed expert(s), click appropriate link.
Nicole Andrews
SOURCE NAI Daus
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Photo: Randy Mayor; Styling: Leigh Ann Ross
Pink peppercorns lend this entrée pretty color and impart a sweet note to the salsa.
Water tally: 7.1 ounces.
4 servings (serving size: 1 fillet and 1/2 cup salsa)
+ Add To Shopping List
1 1/4 cups chopped pineapple
1/2 cup chopped red onion
1/4 cup chopped fresh cilantro
2 tablespoons flaked sweetened coconut
2 tablespoons fresh lime juice
1 jalapeño pepper, finely chopped
2 teaspoons pink peppercorns, crushed and divided
1/2 cup panko (Japanese breadcrumbs)
3 tablespoons finely chopped macadamia nuts
1/2 teaspoon sea salt, divided
1/2 cup light coconut milk
2 tablespoons low-sodium soy sauce
4 (6-ounce) mahimahi or other firm white fish fillets
1 1/2 tablespoons olive oil
Cooking spray
1. Preheat oven to 400°.
2. Combine first 6 ingredients and 1 teaspoon peppercorns in a bowl; set aside.
3. Combine panko, nuts, remaining 1 teaspoon peppercorns, and 1/4 teaspoon salt in a shallow dish. Combine milk and soy sauce in another shallow dish. Sprinkle fish with remaining 1/4 teaspoon salt. Dip one side of fish in milk mixture; dredge dipped side in panko mixture.
4. Heat oil in a large nonstick skillet coated with cooking spray over medium-high heat. Add fish, crust side down, to pan; cook 3 minutes. Turn fish over, and bake at 400° for 10 minutes or until fish flakes easily when tested with a fork or until desired degree of doneness. Serve with salsa.
Created date
July 2008
Nutritional Information
Calories 331
Caloriesfromfat 37 %
Fat 13.6 g
Satfat 3.8 g
Monofat 7.6 g
Polyfat 1 g
Protein 34.5 g
Carbohydrate 18.3 g
Fiber 2.5 g
Cholesterol 124 mg
Iron 2.8 mg
Sodium 743 mg
Calcium 49 mg


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Welcome to the Mathematics Education Database
MathEduc (formerly MATHDI) is the only international reference database offering a world-wide overview of literature on research, theory and practice in mathematics education. MathEduc also covers education in computer science on the elementary level. The scope includes literature for all school levels up to university education, teacher education, general and vocational education. About 500 journals from all over the world are evaluated as well as books and teaching material.
MathEduc is edited by Gesellschaft für Didaktik der Mathematik (GDM), the European Mathematical Society and Fachinformationszentrum Karlsruhe in cooperation with The International Commission on Mathematical Instruction (ICMI), Editorial Unit Debrecen Zentralblatt MATH, Hungary; ERIC, USA; FIS Bildung, Germany; Pädagogische Fakultät Karls-Universität Prague, Czechia; PUBLIMATH, France; SANU, Serbia; SEIEM, Spain.
Editor-in-chief of MathEduc is Prof. Dr. Ulrich Kortenkamp (Potsdam).
FIZ Karlsruhe decided 2016 to support a proposal for a future free access to the database which has been worked out by the editor-in-chief and the German Society for Didactics of Mathematics (GDM).
The German Society of Didactics of Mathematics (GDM) is happy to announce that starting 2017 they will offer the content of MathEduc for free and open to everyone. In addition, it is planned to allow members of the mathematics education community to contribute to the database and create and edit content.This will need some technical work behind the scenes and a lot of organizational and structural work, so MathEduc will be offered in its current form until the replacement platform is up and running.
For any further questions or suggestions regarding the continuation of MathEduc, feel free to contact the editor-in-chief Prof. Dr. Ulrich Kortenkamp: kortenkamp(at)matheduc(dot)org


text:
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No Exam access until payment in full is received.
**Coupon codes or discounts cannot be applied.** Payment Plan Terms and Policies
Note: The program is 100% online. The image to the right is a representation of the materials you will access immediately online. No materials are mailed to you.
- Learn proven techniques for helping your clients to increase energy, improve their health and decrease dependence on medications
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This state-of-the-art Fitness Nutrition Coach program is an easy-to-use, interactive, 100% online training program. You will complete the entire program from the comfort of your home or office.
This is the perfect program for you if you now want to educate your clients about healthy nutritional habits.
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NESTA's Fitness Nutrition Coach program is designed for Personal Trainers, Life Coaches, Registered Dietitians, Certified Diabetes Educators, RNs, and everyone interested in the latest advancements in nutrition, and additional income opportunities in the health & fitness industry.
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What are my career options? How will I make a living with this credential?
The great thing about becoming a Fitness Nutrition Coach is that you have endless career and business opportunities. Some primary careers include: Working with clients at a gym, health club, fitness center, spa or resort. You can train and coach your clients indoors or outside. You can also operate your own facility. You can train and coach clients one-on-one in their home, your home, or your office. Many experts with this credential train in groups to help more people and earn more money per hour. In addition, you can seek out alternative (and frequently very lucrative career opportunities) as a blogger, writer, podcast host, author, online content provider, online video host or publisher of digital education products. You can also offer your services online to individuals, small groups or large groups. You can use fun online communication/collaboration platforms such Skype, Google Hangout or iChat for your training/coaching services. You can become an expert for authority websites such as WebMD, eHow and Livestrong. You can become a frequent expert guest on podcasts, radio shows, TV talk shows, news programs or in industry publications. The list of opportunities is truly endless. Nothing is hold you back. So, go make a difference today!
How will I get clients?
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Nutrition Concepts
The process of nutrition, motility and anatomy, the mouth and esophagus, stomach and intestines, enzymes/hormonal control, basic energy requirements, anaerobic and aerobic energy, energy and ATP, ATP and nutrition and applications for clients.
Understanding Components of Nutrition
The macronutrients, carbohydrates and glucose needs, protein and amino acids, fats and their vital role in human function, water as a macronutrient and the Glycemic Index
Nutrition Requirements
Vitamins from foods consumed and mineral intake requirements
Assessing Nutritional Needs:
Body Composition, BMI and approaching change in biometrics
Understanding Alternative Approaches:
Supplement usage and ergogenic aids
Performance Nutrition:
Easy-to-learn math formulas for Fitness Nutrition Coaches and practical suggestions for optimizing performance
Make the move to become a nutrition expert today!
Fitness Nutrition Coach program details
Continuing Education Units: NESTA 1.5 CEUs, MMACA 1.5 CEUs, ITCA 1.5 CEUs, ISSA 15 CEUs, NSCA 0.8 CEUs, Spencer Institute 1.5 CEUs.
Recertification Requirements: None. Certificate does not expire
Prerequisites: None
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Top Definition
95% of red sox fans as of 2005. made up of mostly fat, irish, red faced women and scrawny white homeboys who will wear their 2004 world championship tilted to the side like a god damn monkey while their over sized manny jerseys will hang all the way down to their knees. 10 years ago these bandwagoners didn't have to suffer watching mo vaughn gain 300 pounds, jose offerman trot around the bases like he was a in beer softball league, or mark portugal tripping over his own feet while pitching off the mound in almost every god damn start. But now they feel like true fans because they can name 3 players on the team.
That bandwagon sox fan over there just yelled "Go Red Sox" then "GGG-Unit" after, lets go beat his ass
by Shaunydigital July 30, 2005
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Great mall with plenty of stores to shop from! There is also a lego store located about 1/4mi down the main walk ☺
Easily accessible by car with a big car parking (unfortunately for payment at 1,90 eur/hour). It's a nice fusion of modern and ancient architecture done by 3 floors with a lot of shops inside (approx. 100). The shops are mostly representatives of big brands like H&M Douglas etc. There is also a Rewe supermarket (not so big) and many bars...
Excellent shopping mall for brands and for non- expensive clothes for men, women and kids. Saturn satisfies the requirements of computer and handy shoppers. A selection of cafes and restaurants satisfies the stomach too. Massage is provided by special chairs to relax you after the shopping trip.
This is a good place to go especially if it rains or in...
The Europa Galerie in Saarbrucken is conveniently located in front of the railroad station with an additional parking structure for those driving into town. This last is handy, but not exactly cheap. The Galerie includes a REWE supermarket with their usual wide assortment including 'bio' products, drinks, fresh fruits and vegetables, bread, etc. in addition to clothing shops such as...
Great place to shop in Saarbrucken. 3 stories of every sort of clothing, hobby, children's stores. Also usually have nice activities/events throughout the mall. 4 areas full of interactive puzzles as the special "event" the last time we visited which was a nice break and diversion for the kids while I was making them try on/ buy new clothes. Lots...
This mall is overlooked since K-Town is closer to Ramstein but 45 minute drive away to the west is Saarbrucken Germany where there are numerous shopping opportunities, restaurants, and night life. Europa Galerie should be your starting point for exploration just park your car and everything is walking distance!!!!!
The new Shoping Center offers to you a wonderful area where you can find attractive shops for every Idea you might have in your mind. Also good food and drinks are there, so if you have time enough you can spend nice hours there.
Nice shoppingmall and for us a very welcome alternative because of the rain during our short stay in Saarbrucken
If you are looking for a place to visit on one of those Saarbrücken rainy days than this is a great place to see. Loved the connection between old (the building itself) and modern (the shops). They have Starbucks so I suppose that's a pretty great thing also :)
The high street and this mall have a good selection of clothes stores but the whole town is really rough and we didn't have a pleasurable experience here. Lots of beggars and half the population walking round with Primark bags! The mall is easy to get to by car.
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Evi is our best selling mobile app that can answer questions about books, music, films, conversions, history, people, places and much more.
To experience the full power of Evi you can download her app for free on iOS, Android and Kindle Fire.
Let It Be, the 1970 film about The Beatles rehearsing and recording songs for the album Let It Be in January 1969
The Compleat Beatles, released in 1984, the two-hour documentary, chronicling the career of the "Fab Four"


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Each month, direct to your email inbox, we'll send the best camping news, tips, recipes and more, to enhance the camping lifestyle that you love so much. Learn More
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Open All Year
Reserve: 800-562-3460
Info: 419-477-5255
3506 Township Road 34
Bluffton, OH 45817Get Directions
We are conveniently located beside Interstate 75 at Exit #145 (for SR 235, Ada, Mt. Cory) in Northwest Ohio. Our I-75 intersection has the big blue camping signs with the KOA logo. SOUTHBOUND: 50 miles from Toledo; 30 miles from Bowling Green; 15 miles from Findlay NORTHBOUND: miles from Dayton; 20 miles from Lima.
GPS: N40.914827. W83.816918Get Google Directions
Camper Rating 4 out of 5


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Category:Holy Name of Jesus R.C. Church
From Wikimedia Commons, the free media repository
Holy Name of Jesus Roman Catholic Church on English Wikipedia.
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- 1900s architecture in New York City
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- Morningside Heights, Manhattan
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- Amsterdam Avenue (Manhattan)
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Applying at UEI Begins Here
UEI believes that applying and being accepted to the school of your choice shouldn't be a time-consuming or challenging process. That's why we make every effort to streamline our admissions guidelines and make them easy and encouraging for you to follow.
Applying to UEI begins when you contact us. You will meet with one of our admissions professionals in person to discuss your educational goals and to submit the information we need for you to begin the process. You'll have the opportunity to tour the campus location you choose and ask questions.
UEI wants you to discover and pursue the career education that will benefit you. Get started today!


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- Age / Gender:
- 25, Female
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- In a swamp
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- 10/23/08
- All Stats >
User Statshot
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Level 22 Gamer
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Rullo Rated 4.0600 Stars An addictive and challenging simple math puzzle game Puzzles - Other Cloudia Rated 3.4900 Stars A platformer where you can't jump. Action - Platformer - Puzzle Return to Riddle School Rated 4.1400 Stars Escape from school in this remake of the classic web game, Riddle School Adventure - Point 'n Click Lost Ethereal Rated 3.9700 Stars Save your dead family from the spirit world Adventure - Other
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Emmy's Christmas Gift Rated 4.1400 Stars Actors for the Harry Potter films wish my sister a Happy Christmas Music Video [Persona 4] Animated Comic Dub (part 1) Rated 4.0700 Stars PERSONA!! Comedy - Parody Eddsworld - The End Rated 4.6900 Stars The grand finale of Eddsworld Legacy Comedy - Original LoZ: Link Meets Zelda Rated 3.6800 Stars Young Link meets Zelda for the first time. Comedy - Parody
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Hard Master 100 Points Clear all hard Puzzle Medal Stats.
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Normal Master 50 Points Clear All Normal Puzzle Medal Stats.
Hard Puzzle key 25 Points Clear last Normal puzzle Medal Stats.
Oracle 10 Points Premonition of imminent misfortune Medal Stats.
Demon 25 Points An evil encounter Medal Stats.
Cursed 25 Points A slave for all eternity Medal Stats.
Threat 5 Points A deathly forewarning Medal Stats.
Escape! 50 Points Escape! Medal Stats.
Skull 10 Points Skull Medal Stats.
Total Medals Earned: 822 (From 108 different games.)


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All of IGN.com's video game podcasts jammed into one feed. It's like one of those little clown cars, but for your ears.
February 6th, 2015
Episode 232 of 1035 episodes
Luke, Lucy, Cam and Bakertalk Ghostbusters casting, VR racing and the future of episodic gaming.
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Invokana (canagliflozin) tablets
Detailed View: Safety Labeling Changes Approved By FDA Center for Drug Evaluation and Research (CDER)
May 2016
Acute Kidney Injury and Impairment in Renal Function
- INVOKANA causes intravascular volume contraction and can cause renal impairment. There have been postmarketing reports of acute kidney injury, some requiring hospitalization and dialysis, in patients receiving INVOKANA; some reports involved patients younger than 65 years of age.
- Before initiating INVOKANA, consider factors that may predispose patients to acute kidney injury including hypovolemia, chronic renal insufficiency, congestive heart failure and concomitant medications (diuretics, ACE inhibitors, ARBs, NSAIDs). Consider temporarily discontinuing INVOKANA in any setting of reduced oral intake (such as acute illness or fasting) or fluid losses (such as gastrointestinal illness or excessive heat exposure); monitor patients for signs and symptoms of acute kidney injury. If acute kidney injury occurs, discontinue INVOKANA promptly and institute treatment.
- INVOKANA increases serum creatinine and decreases eGFR. Patients with hypovolemia may bemore susceptible to these changes. Renal function abnormalities can occur after initiating INVOKANA. Renal function should be evaluated prior to initiation of INVOKANA and monitored periodically thereafter. Dosage adjustment and more frequent renal function monitoring are recommended in patients with an eGFR below 60 mL/min/1.73 m2. Use of INVOKANA is not recommended when eGFR is persistently less than 45 mL/min/1.73 m2 and is contraindicated in patients with an eGFR less than 30 mL/min/1.73 m2.
March 2016
- History of a serious hypersensitivity reaction to Invokana, such as anaphylaxis or angioedema.
Hypersensitivity Reactions
- Hypersensitivity reactions, including angioedema and anaphylaxis, have been reported with Invokana. These reactions generally occurred within hours to days after initiating Invokana. If hypersensitivity reactions occur, discontinue use of Invokana; treat and monitor until signs and symptoms resolve.
Postmarketing Experience
- Anaphylaxis, Angioedema
September 2015
Bone Fracture
- An increased risk of bone fracture, occurring as early as 12 weeks after treatment initiation, was observed in patients using canagliflozin. Consider factors that contribute to fracture risk prior to initiating Invokamet
Clinical Studies Experience
- In a pool of nine clinical trials with mean duration of exposure to canagliflozin of 85 weeks, the proportion of patients who experienced falls was 1.3%, 1.5%, and 2.1% with comparator, canagliflozin 100 mg, and canagliflozin 300 mg, respectively. The higher risk of falls for patients treated with canagliflozin was observed within the first few weeks of treatment.
Bone Fracture
- The occurrence of bone fractures was evaluated in a pool of nine clinical trials with a mean duration of exposure to canagliflozin of 85 weeks. The incidence rates of adjudicated bone fractures were 1.1, 1.4, and 1.5 per 100 patient-years of exposure in the comparator, canagliflozin 100 mg, and canagliflozin 300 mg groups, respectively. Fractures were observed as early as 12 weeks after treatment initiation and were more likely to be low trauma (e.g., fall from no more than standing height), and affect the upper extremities
Renal Impairment
*Section edited to read:
- The efficacy and safety of canagliflozin were evaluated in a study that included patients with moderate renal impairment (eGFR 30 to less than 50 mL/min/1.73 m2). These patients had less overall glycemic efficacy and had a higher occurrence of adverse reactions related to reduced intravascular volume, renal-related adverse reactions, and decreases in eGFR compared to patients with mild renal impairment or normal renal function (eGFR greater than or equal to 60 mL/min/1.73 m2). Dose-related, transient mean increases in serum potassium were observed early after initiation of canagliflozin (i.e., within 3 weeks) in this trial. Increases in serum potassium of greater than 5.4 mEq/L and 15% above baseline occurred in 16.1%, 12.4%, and 27.0% of patients treated with placebo, canagliflozin 100 mg, and canagliflozin 300 mg, respectively. Severe elevations (greater than or equal to 6.5 mEq/L) occurred in 1.1%, 2.2%, and 2.2% of patients treated with placebo, canagliflozin 100 mg, and canagliflozin 300 mg, respectively. The efficacy and safety of canagliflozin have not been established in patients with severe renal impairment (eGFR less than 30 mL/min/1.73 m2), with ESRD, or receiving dialysis. Canagliflozin is not expected to be effective in these patient populations.
March 2015
Clinical Studies Experience
Genital Mycotic Infections
- Added...In females, discontinuation due to genital mycotic infections occurred in 0% and 0.7% of patients treated with placebo and canagliflozin, respectively.
- Added...In males, discontinuations due to genital mycotic infections occurred in 0% and 0.5% of patients treated with placebo and canagliflozin, respectively.
May 2014
7.3 Positive Urine Glucose Test
- Monitoring glycemic control with urine glucose tests is not recommended in patients taking SGLT2 inhibitors as SGLT2 inhibitors increase urinary glucose excretion and will lead to positive urine glucose tests. Use alternative methods to monitor glycemic control.
7.4 Interference with 1,5-anhydroglucitol (1,5-AG) Assay
- Monitoring glycemic control with 1,5-AG assay is not recommended as measurements of 1,5-AG are unreliable in assessing glycemic control in patients taking SGLT2 inhibitors. Use alternative methods to monitor glycemic control.


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james singer wrote:
I've got a seedling bottle gourd growing in a 1-gallon pot in the
lathhouse; it is just beginning to produce secondary leaves. And I need
advice. I want to plant it somewhere so it will produce a bottle or
three, but I have no idea what it wants, including whether it needs to
go in the ground or can stay in a large pot [say, 15 gallon]. I know it
may run all over hell's halfacre no matter where it's planted, but
that's okay--I've got the room. But does it want/need to climb?
Island Jim
My sister grows gourds of various sizes & types in Sarasota. She
grows them in an open field, some on fences, some not. Doesn't seem
to matter. I recall she may set some large ones on rocks to keep them from
rot in the rains.
Jim Fisher
Vienna, Virginia USA
USDA Zone 7
Max. 105 F [40 C], Min. 5 F [-15 C]
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Tennille Paterson Wardrobe Stylist
MUA Jess NicholsMakeup Artist Female Brisbane, Queensland, Australia
Mayhem # 2980896
About MeMy name is Jessica Nichols. I am studing my Diploma of Makeup at the Acadmey of Make up Brisbane and am looking to get a a portfolio of work done. I am willing to work for free if photographers are willing to let me use their photos of my work for my portfolio. I feel very confident in photography and fashion makeup. We have also done face paint, and hair styling. I have had some work experience on catwalks and done previous works for photographers. (am waiting for photos to be sent out.) Driving to locations is not a problem for me, i have a full kit, creative and eager to get my foot in the door to become a well known makeup artist.
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text: How to Prepare the Space Shuttle for Another Mission to the ISSAdam Frucci12/22/08 3:30pmFiled to: SpaceISSEndeavorSpace Shuttle23EditPromoteShare to KinjaToggle Conversation toolsGo to permalink The Big Picture has a photo essay showing us every step that the Space Shuttle Endeavor goes through between missions, from touching down to taking off again. Advertisement Endeavor has gone through this process a whopping 22 times in the past 16 years and will hopefully go through it many more times in the future. This batch of photos show it as it progresses from its landing from its last mission on March 26th through its return from its following mission, 9 months later. Incredible stuff. [The Big Picture]Reply23 repliesLeave a reply


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Donate Now
The UNC Gillings School of Global Public Health greatly appreciates your support!
You can support the work of public health, students and our School in many ways:
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List actors include Kenneth Mars, Dabney Coleman and more.
If you want to answer the questions, "Who starred in the movie How to Marry a Billionaire?" and "What is the full cast list of How to Marry a Billionaire?" then this page has got you covered.
This cast list of who was in How to Marry a Billionaire includes both lead and minor roles. (14 items)
- 1
Dabney Coleman Tootsie, WarGames, The Towering Inferno
- 2
Gabrielle Anwar Scent of a Woman, The Three Musketeers, Things to Do in Denver When You're ...
- 3
Michael Bowen Kill Bill Volume 1, Django Unchained, Kill Bill Volume 2
- 4
Kenneth Mars Young Frankenstein, The Little Mermaid, Butch Cassidy and the Sundance Kid ...
- 5
John Stamos Private Parts, Farce of the Penguins, Party Monster
- 6
Katherine Helmond Brazil, Cars, Fear and Loathing in Las Vegas
- 7
Hamilton Camp Dick Tracy, Heaven Can Wait, Joe Dirt
- 8
Shemar Moore Diary of a Mad Black Woman, The Brothers, The Seat Filler
- 9
Rhea Perlman Class Act, Matilda, Sunset Park
- 10
Joshua Malina A Few Good Men, The American President, In the Line of Fire
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Roark Critchlow Mr Deeds, Cadence, Shark Swarm
- 12
Shelley Malil The 40-Year-Old Virgin, Holes, My Favorite Martian
- 13
Carole Davis Mannequin, Piranha II: The Spawning, The Rapture
- 14
Jeanne Chinn Lethal Weapon 4, Fat Albert, R.S.V.P.


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Lifeproof Lifeproof White
- New - Open Box 1 Left
- Item looks and feels new Packaging may show wear
List Price $89.99
Please note: BLINQ sells products in multiple conditions (new, open box, refurbished, etc). Not all reviews are reflective of the condition that you may purchase.
Lifeproof Lifeproof White is rated out of 5 by 422.
Rated 5 out of 5 by Echan from Perfect Case for my New Phone! I have had many Lifeproof cases over the years for my iPhone 4S, iPhone 6, and now my iPhone 6S Plus! Lifeproof has definitely improved over the years and I could not be happier with my new purchase! The buttons are easy to push and they respond quickly! The fingerprint reader is extremely fast, just like it is without the case on it.The charging port and headphone jack are bigger than before so that you can use your headphones or any charger with no problems! I think this case is perfect for anyone that is looking for a protective case that doesn't add bulk. My phone is still sleek and the black case looks great with my rose gold! I wouldn't trust my phone with any other case!
Date published: 2015-12-23
Rated 5 out of 5 by rachel from I already own two of these! When I initially purchased the Fre case, I was a little doubtful. I drop my phone a lot, and am always cracking the screen protector. After using it for about a month, I am very happy with this case and can not imagine using a flimsy case anymore. It is a little on the pricey side, but worth it, since the phone is worth hundreds of dollars. I also received a scratch on my screen of the case, and it proved not to be waterproof, the LifeProof customer service took care of it immediately. I'm very happy, and currently own both the purple and pink cases (I couldn't decide on a color!). Also convinced my boyfriend to buy one for his new 6S.
Date published: 2016-02-24
Rated 3 out of 5 by TheMom from Every day life of a single mom The case protects my phone very well from the elements and from being dropped and manhandled by my awesome children, and at times myself :) Right now the only complaint that I have is that, a lot if the time, people that I am talking with on the phone tell me that they have a hard time hearing me. They say similar things like "it sounds like you are really far away" or "it sounds like you are in a tunnel" or "are you covering the mouth piece when you talk because your voice sounds muffled". Those are the popular top three. I hear it so much that I am debating returning the case to see if that improves. On a positive note, I LOVE the crushed purple color!!
Date published: 2016-02-23
Rated 2 out of 5 by DaniK from Mother and Student I bought this case a few months ago, and i have been using lifeproof since 2011, and i was so excited when they made the pink and green FRE for iphone 6 plus. Me and my husband both got them and both our phones sound like we are talking through tunnels. Being a mother i make doctors appointments pay bills, deal with atleast 35 phone calls a day and this is ridiculous when i have to get transferred to someone else at the doctors office because they cant hear me through my phone. i love lifeproof and they used to send our cases for free now we have to pay for a new case skeptical if i want to spend anymore money into the phone or throw in the towel on this one....
Date published: 2016-11-17
Rated 5 out of 5 by Railroader from The Ultimate IPhone Case After waiting, which seems like forever ago, it has finally arrived, and I must say it was worth the wait. I've tried other cases before now, and all with disappointment, I've been looking forward to a case which can withstand the elements that my phone takes on account that I work outdoors for a living, the snow, rain and etc. It's lightweight, and it's not big and bulky like some of the other brands on the market today. If you're in the market for a great case I highly suggest the FRE, everything works great, and you should give it a try, you will not be disappointed, this is the ultimate IPhone case out on the market today!!!
Date published: 2016-01-16
Rated 4 out of 5 by Steffff from Pretty awesome! I didn't buy this case because i'm active i'm just very clumsy and always break my phone. So far this case has been amazing and well worth it its more slim than I expected so It fits anywhere including my pockets. The rubber material makes it grip on to your hands and pockets so its hard for your phone to slip out of anywhere. I havent water tested but i'm not big on swimming or underwater pictures so I don't plan on getting it wet. The only downside is you have to open the bottom part to talk on the phone because noone can ever hear me when its on. Other than that I am very satisfied.
Date published: 2015-12-29
Rated 4 out of 5 by FlyBoy from Excellent Case,but..... This case is almost everything I had hoped for. My phone has been dropped numerous times, gotten wet, and has survived without a scratch, using the Fre. I have not even had any problems with the charging door or earphone plug that others seem to have issue with. The thin case allows me to carry this phone comfortably in a pocket. The only issue I have, is that when I talk, most people complain that they have a hard time hearing me. Given the other pluses, I am very happy with the design and protection this case offers. Hopefully, future designs can improve on the ability to be better heard using the phone, without a headphone.
Date published: 2016-02-01
Rated 5 out of 5 by Amberalert from Fre I only buy life proof cases, by far this one has been the best from the color to how lightweight and convinent it is when sitting poolside and you get splashed with water no worries your phone is good. I also love the way the new charger port is made it doesn't have those annoying little latches that break after opening and closing it a few times like the nuud case does. Most people look at the price and say it's too high but it's worth every penny and it pays for itself over and over especially if you love water and don't want to worry about your phone getting wet. I hope they get more colors because from now on I'll only be buying the fre cases.
Date published: 2016-02-15
- Features
- Set out with LifeProof FR for Apple iPhone 6 Plus/6s Plus and live with no limits. Waterproof and drop proof, FR for iPhone 6 Plus/6s Plus has the guts to go into the thick of it and come out unscathed. Featuring a built-in screen protector, FR shields your iPhone 6 Plus/6s Plus from Mother Nature s worst. From ocean shores and mountain trails to desert dunes no environment is too extreme for LifeProof FR . Note:This product works on iPhone 6 plus only. You may experience some distortion/muffling of the speaker and microphone. Gap for charging port will fit only apple brand chargers
- 660543386353
- Brand
- LifeProof
- Model
- 77-52559
- Part
- 77-52559
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- Retailer needs to move overstock, open box & refurbished inventory.
- BLINQ receives inventory and professionally inspects each item.
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