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Self Upgrade 1.7
Show creativity and create the unique character from a set of the available details. Want to attach a jet engine to a robo-bunny? No problem, the originality of possible combinations is limited only by your imagination! After that you have to use your speed and reaction and complete dynamic and fast mini-games, that will develop your memory, erudition, skills of the oral account and the "blind" typing. Strain each cell of the body and justify the
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Collect URL 1.0
Collect URL scans internet like a search engine bot. Starting from the user entered URL, it lists all the links on the URL. Then it recursively scans all the links in the list. User can limit Collect URL to collect single domain only. File extension ignore list is editable. Connection and response timeout values are editable. Also user can change user agent value for HTTP and HTTPS connections. Collect URL is developed by VOVSOFT.
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Winter Extreme Racers 1.98
3d rally racing game. What could be more extreme than charged SUVs, overcoming snow bumps of the Far East region of Russia? Win the races and get incredible new cars. Only skilful control of these powerful vehicles will beat the game completely.
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Me Alone Reissue 2.6
On the ground, there was an apocalypse. Many people have turned into monsters that eat other people. At that moment of this doomsday, the protagonist was working at the gas station far from the city. He's the only survivor in this place he must defend against zombies that are closing in. His arsenal has includes 6 weapons which will be increasingly at his disposal as the game progresses. Stay alive as long as possible!
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1001 Mission 5.0
Mission 1001 is a simple but interesting breakout game. Despite the fact that the game is called the 1001 mission, there are actually only 60 levels in the country. There are 7 types of blocks of different strength as well as several different bonuses. Different backgrounds will keep you engaged. The objective is to destroy all the blocks and collect enough points to be in the top ten, or even #1. Enjoy the game!
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Tractor Game 2.8
Take the helm and go conquer the village! On The tractor! Only you, the nature and the steel monster under you. Immerse yourself in the deep atmosphere of nature, take a break from city life and a bad ecology!
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WinSleep by MollieSoft 220.127.116.11
WINSLEEP by MollieSoft keeps your computer asleep (while not too busy) as much as possible during periods you specify. ** Runs on Windows 7, Windows 8.1 or Windows 10. ** Provides a detailed time-line graph showing when your computer was awake, asleep, or hibernating. ** Sleep Journal shows when/why your computer woke up or went to sleep. ** Provides convenient Sleep and Hibernate buttons for manual use when desired. ** Use remote viewer WinSleep Monitor to connect from anywhere! ** Shows the current CPU/Disk/Network usage percentages for your computer. ** Define multiple sleep schedules (daily, weekly, or monthly time slot), each with a designated sleep policy with its own CPU/Disk/Network usage limits. ** Set wake schedules and an optional task (program) to be run at each wake. ** Helps prolong the life of your desktop computer. Your disk drive is not spinning, motherboard is not powered, fan is not running (and accumulating dust inside the computer casing), and your monitors are in standby mode. ...
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Falco Christmas Gems 7.4
What is Christmas? It is the most light and joyful holiday there is! It is when all people loving and dear to you gather in one circle, have fun, and give each other gifts. Unfortunately, this holiday happens only once a year... We reproduce all of the bright and beautiful joy that embodies the magic of Christmas.
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Duck Hunter Dodger Doom 3.7
Duck Hunter Dodger Doom app will certainly remind you your childhood and make smile! If you're hungry for adventures, flying duck hunting is exactly what you need! Duck Hunter Dodger Doom app has many great features,each flying duck is very difficult bullseye.It's very fast,so you'll have a choice ofgunsand shoot any duck, it shouldn't escape! There're more than one duckflying across your display, your goal is to kill not only one duck, but as ma
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Desolators 4.5
The last free country on Earth The last stronghold of freedom and democracy Kingdom of the Netherlands American totalitarian barbarians And French renegades ATTACK! The front line of defense Only YOU can stop the crushing tread of DESOLATORS...
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Rogue Within 2.4
You mysteriously appear in the evil sorcerer's castle. You must escape, and in order to do this must find the hidden key. Only if you capture the key will you be able to escape to freedom, but it's not that simple. Along the way you will meet many dangers. The only way to survive in this mysterious journey is to look for new objects, food and weapons to be able to defeat the bloodthirsty enemies.
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Dead Void 2.3
You play a farmer who realized that the zombie apocalypse happened on earth. Taking their weapons he will pass through dangerous places populated by crowds of the walking dead. Help the unfortunate farmer, who remains the only living person on the whole earth, find shelter. Your path will pass through the city streets, sewers and hospitals. Search for new weapons and ammo and destroy as many zombies as you can!
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Bears Dream 4.7
Help the Bear to achieve his child's dream to earn enough to build a ship in this fun time management game! You manage the main character, a hard working Bear, who grows and sells a variety of plants, catches fish and builds devices to produce some new goods. A number of unique upgrades and bonuses are waiting for you! Remember, if the orders are not fulfilled in time, you can lose not only money, but also bonus stars that are necessary to ..
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JELLY IN A HOLE is a game about Jelly jammed in a hole, as the name suggests. Escape is only possible using structured ladders of boxes. There are 4 types of boxes (metallic, sturdy wood and cardboard). Each of them has its own strength. The heavier box will easily destroy the lighter one. Controls are right and left arrows (with the exception of the menu). The game has 11 levels that increase in difficulty, not only to solve the problem but also
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All Billiards 4.5
"Billiards club " is a 3D pool simulator, giving you full reality sensation. The big amount of games, beautiful graphics, realistic ball movements - only some features of this billiard. You can play with your computer in three difficulty levels, with a partner on the same computer and in the network. For each type of games stipulated separate tables. Tables, spheres and cue are made according to their real sizes. In game special tracking mod
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5 nights with a vodka. Your aim to survive in a wine storehouse, use stock in a right bottom corner of the screen. Use it only when you have noticed a phantom which hides in spirits.
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OrgFinances 2.9
OrgFinances by BinaryHouse - the advanced home accounting tool, which can be used not only by home users, but also by sole traders and small businesses. Requiring no accounting skills or special qualifications, it helps you successfully perform finance management, track income sources and cut down unimportant expenses. Simultaneous management of several budgets is supported, as well as a handy scheduler and a calendar of appointments.
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Danger Zone 5.4
Dander Zone is an addictive 3D shooter. You find yourself in a dark abandoned hospital where they conduct experiments on humans, some of whom have turned into zombies. You'll have to fight these creatures. They know nothing, only that they want to kill you. The only chance to survive is to kill all of them and find the exit from the hospital.
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PDF Data Extractor 1.05
PDF Data Extractor can extract certain text information within the PDF, This is an ideal product if you had for example a PDF statement that you need to extract data like Account Number, Name, Address and output this information into an Excel CSV file. It uses horizontal, vertical text position matching and for more advanced matching it has a rules system for conditional matching, e.g. Only take match when Account Number: text is on the same page
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Maze Of Dark Shadows 5.2
This adventure horror puts you in a maze of dark shadows. The main character of the game will try to find a way out of the dark, terrible maze. His only defense is a flashlight, which will have to keep powered by finding as many batteries as possible. Also do not forget about the first aid kit, which may restore the hero's health when the evil lurking in the shadows suddenly drains life from him.
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Lotto Logic Lottery Software 7.1.8
Whether you're a regular user or completely new to lotto logic, you'll love the simplicity and ease of use found in Lotto Logic Professional Version 7, advanced lotto software that works. Faster, easier, smarter, more flexible and manageable. New Range Finder and Range Tracker technology are unique powerful features only found in lotto logic which help you home in on those winning numbers unlike any other lottery software has before!
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Lawyers Service 3.1
Lawyers Service combines powerful case management tools for organizing clients, case details, exhibits, documents, discovery, mail, e-mail, phone calls and much more. Lawyers Service is designed to help you effectively keep track of not only your schedule for a particular matter, but all the other associated details that will require your attention before you can easily bring that case to a successful conclusion.
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Skynet Rampage 2.6
"Skynet: Rampage" is a tactical stealth action game set in a post-apocalyptic future. To survive in this new world is not so easy, because you have to battle robots and other creatures of Skynet. Robots have advanced artificial intelligence that takes into account real sights and sounds. They can think on the fly as we can, only faster. You, in turn, will be able to use a variety of futuristic weapons and accessories, such as a laser rifle, the
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Mission Escape From Island 2.4
Mission: Escape from Island - great shooter on the passage with amazing modern graphics! Immerse yourself in the story of a soldier, trapped by destiny into the territory of the enemy army, where nobody can help him and he can rely only on himself! Will he survive in this hell - depends on you. Good luck and have fun!
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Halloween Tavern 1.3
Our restaurant is open again for fantasy creatures, monsters and maniacs only! Today though, a beginner chef walks in and does not know anything and can not do anything about it. But under the strict guidance of your demon-cook he will be able to reach new heights of cooking art. Carefully select the best ingredients for the gourmet-monsters. Avoid bad ingredients to keep the interest of customers. Excellent meals beget decent pay, earn generous
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One of the most underrated destinations on the map, Iran is stock full of UNESCO recognized world heritage sites, as the country has been the base of multiple eastern and western empires over centuries. Its welcoming community, modern infrastructure and independently based commerce give it a strong outlook for the future. So if you are not afraid to take a risky stroll to the lesser traveled destinations, book your cheap flights to Iran with us today!
Bargain deals for return flights to Iran
Business class flights to Iran
Iran Overview
Best Time to Visit
You can go to this region almost any time during the year. It is, on the other hand, better advised to avoid visiting here as a tourist for fun during the two weeks period around Nowruz or the month of Moharram (Islamic calendar month) and the month of Ramadan when the religious activity hinders fun activities. You should check out on Holiday & Events in the calendar for such details. The plains in the country observe extreme weather conditions in summer as well as winter.
Places to Visit and Things to Do
The country is one ethnic mix from the Asian cultures from its East and the Arabic cultures from its West. The country's culture spelled immense grandeur and luxury for its Royal Family while it was ruled by its monarchy, with the royal residence of Saad Abad Palace, The Royal palace and the Forty Column Palace being public museums, this region has overseen the development of the largest empires in Asian history. So remember these places while booking your cheap flights to Iran. The ruins of Chogha Zanbil and Persepolis clearly highlight the same fact; consisting of entire cities with wide-ranging establishment. Strengthening its diplomatic bonds with one of its brotherly nations, the Azerbaijan Museum is an opportunity to explore foreign culture associated with the country. Local commerce can be seen on the rise at traditional market centres like the Naqsh e Jahan Square, where handicrafts and artefacts can be purchased to serve as souvenirs ideal for decoration purposes. The Imam Raza Shrine is one of the largest Islamic landmarks worldwide, along with numerous other landmarks like the ruins of Ali Shah Masjid, Goharshad Mosque and the Blue Mosque; each of them showing the magnanimity of Islamic architectural designs. It has extreme terrains as well as climates, with the northern forests, lakes, the deserts to the east and south, and the mountain ranges forming excellent slopes for skiing, transformed into official natural parks. Among them the most prominent ones are Jamshidieh Park, Chitgar Park and Pardisan Park. . So, pack you bag and get to observe the hidden gem of Asia and reserve cheap flights to Iran to secure an exotic holiday well within your budget.
Getting There
This country is completely accessible with around 70 airports spread across the country. The older Imam Khomeini Airport completely focuses upon international operations, attending nearly 600 overseas flights per week, while a small number of flights land at Mehrabad Airport. Considering all main airports of UK like Manchester, Birmingham and all airports of London, there is Gulf Air, Qatar Air, Ukraine International Airlines, Oman Air, Austrian Airlines and Lufthansa. Direct flights landing in Tehran while departing from London Heathrow Airport. For filtering the best cheap flights to Iran, TravelhouseUK has brought forward deals with multiple foreign air operators like Emirates, Alitalia, Qatar Airways, Gulf Air and Austrian Airlines.
Hotels and Accommodation
The spheres of urban development have led to categories of options available amongst the cities and the towns. We always advise customers to add a hotel to their cheap flights to Iran in advance. International hotels are mostly centered in the main cities in the form of towers and plazas, with grand lobbies, suites and restaurants. Some of the mansions serve as villas, subdivided into guestrooms along with gardens and verandas. In the hustling and bustling commercial areas of traditional souk markets, there are small traditional inns which facilitate divided compartments to serve as sleeping centers with exclusive privacy for travellers. They function primarily as motels for local travellers to avail rest and services while en-route to their business or journey to other destinations. If somehow, you were unable to book cheap flights to Iran and want to cut down on accommodation costs, there are small hotels which have retained their standards from the pre revolution era in the older parts of the cities, facilitating standard beds with televisions and seating areas.
Managing the daily budget
- A single meal at an international fast food chain: £ 2.7
- A large bottle of mineral water: £ 0.26
- An imported pack of cigarettes: £ 1.7
- A local transport ticket: £ 0.12
- An average taxi trip within the city: £ 2
- An international standard luxury hotel in central metropolitan area: £ 130
Flight destinations in Iran
Airlines that fly to Iran
Austrian Airlines (OS)
Air France (AF)
Emirates (EK)
When looking out for cheap Iran flights, what are the general preferences available for booking?
Even though there are global air operators like Etihad Airways and Emirates present to operate between London and Tehran, the bulk of cheap Iran flights are offered by small scale budget carriers. These airlines include Pegasus Airlines, Azerbaijan Airlines and Ukraine international. To minimize airfare rates, these airlines usually take off from airports like London Stansted and London Gatwick.
What if one prefers to choose to fly only with European air carriers when booking Iran flights?
No problem; there are many European airlines as well whose seats are available for booking to assure the satisfaction of our client's standards. Austrian Airlines, Lufthansa, Alitalia and Aeroflot come in this category for all clients.

subset: commoncrawl


text:
B.o.B ft. Young Jeezy, Young Dro & Yo Gotti – We Still In This Bitch (Remix)
Off Hustle Gang's G.D.O.D. mixtape dropping May 7. Hit the jump to stream the remix.
Off Hustle Gang's G.D.O.D. mixtape dropping May 7. Hit the jump to stream the remix.
it's not something you do, bruh.
it's something you embody.
a mans mantra.
my bright yellow Vikings hoodie tho >>>>>
Leather facin in 3….2…
it's not something you do, bruh.
it's something you embody.
a mans mantra.
Lmao… U niggas are some characters for real
Don't lie LAND lol
You still rocking that Diplomats tee-shirt with the Big Mac stains
LadyLord gotta febreeze that shit or something my brother..
Keep goin(c) another victim of mine
This nigga got that poetic Rudyard Kipling ether.
That Lord Byron steez
I'ont respect it
smh. that wasn't ether. thas light.
Donald Goines>>>William Shakespeare
You a cranky lil nigga ain'tcha? Lol
No more coffee for this guy
Olympians >>>>12 disciples
Just found out Karen Finney is getting her own show on msnbc
Great news
Hopefully in prime time at like ten o'clock
She's a big woman whole lotta body
Legion of Superheroes>>>>The Founding Fathers
Jimi Hendrix>>>Mozart
Just as they say Obama is finished
The economy starts to show signs of life
This a new era for black men
You can destroy yourself sure
But its getting harder for them to destroy YOU
been listenin to the chance the rapper nigga for the last half hour
i respect it
he half kendrick lamar half eminem half b-ease and half charles hamilton
*daps eric royster*
Bout to install boot camp so I can compose this masterpiece
Smh at FL studio not working on OSX
Smh. Missy Elliott sonned Drake.
leave nahright now! your opinion on music is wack
He gon put that ill Chinese slant on the sample
Ancient Chinese secret beat making style number 1 Mister Blooks
Just make sure A-1 can put in on the album that's all
No filler material chypher-San
"From that day on everything was different," he remembers, his voice rising with excitement. "I said, 'Oh shit, I'm high. Buck. Dawg. Boy. I'm high. Dawg. Boy. I'm high.' I said, 'I wish air was weed smoke.'" The only drug he says he'll never try again is heroin; he unwittingly snorted too much once and ended up vomiting convulsively. His best-ever drug experience came during a photo shoot for Ozone Magazine: "I was on Ecstasy, I was on syrup, I was on my weed, my coke, and some Xanies. Everything was so balanced and perfect. That day, I told myself my new name is Five-Drug Minimum."
Wiz Latifah bars on "Landing" >>>>
Wiz Latifah bars on "For Her" >>>>>
"Cabana" and "For Her" is the 2 best songs of the year so far
*daps The Kid Frankie while wearing rubber gloves and surgical mask*
Cypher hurry up
i put all my chips to the middle of the table, and bet on you to cook up a better joint than Troll Clinton
make a rapper friendly beat for the good people at LMG
24 minutes
That Reese Witherspoon footage is funny as hell
Remember when we used laugh about her slobbing Bookem Woodbine down
It was like only me and Land saw that movie
She went in on that nigga lol
He husband ratted her out right in front of police
"She's had more to drink then I have.."
Antione Dodson just came out as straight by the way
He's a black nationalist now
TS-LTE Respect bruh..it was only right I shout u out bruh RealShit..Kev da same applies 2 u & I'm def gon take ya advice in2 consideration..I also liked Word Al description of my style as well as HW..jus a mixture of my influences I guess..Free J u kno I fucc wit u & ya music so das what it is..Trill thanx 4 da inspiration although it was part dat & part da state of mind I was in..B u kno I respect u 2 da utmost lyrically still u & land da best lyricist on nah in my eyes RealTalk fucc what everybody else talkn bout..speakn of land woulda luv 2 hear his feedbacc also I woulda luv 2 hear feedbacc from Sihk 2..Last but not least Cyph u kno I fuccd wit da 1st beat u upped so I'm def eager 2 hear ya take on da joint..I'm a jus gon put it out dere dat I'm a hop on ya shit 2..wanted 2 do somethn like dis wit Tron/Sihk but it ain't work out like dat but all in all I overly appreciate da luv I got 4 dat shit means alot..and it won't b da las time I do somethn 4 y'all I promise..shouts 2 Frank & Gob on GP


text:
Is this attraction good for couples?
Is this attraction suitable for all ages?
Is this attraction pet friendly?
Would this be a good hot day activity?
Is this an outdoor attraction or activity?
Is this attraction a hidden gem or off-the-beaten path?
Is this attraction a good picnic spot?
Is this attraction exciting, unusual, or risky to visit?
Does this attraction require above average amounts of physical activity (long walks, climbs, stairs or hikes)?
Does this attraction have good scenic or skyline views?
Thanks for helping!
This park has a lot to offer. It is well laid out with great trails, scenic overlooks and a wonderful visitors centre. Wear comfortable shoes and do not forget your camera.
Devil's Hole is great for hiking. It's an average strenuous level of hiking. The scenery is beautiful. Great for trail running. If you are visiting the falls definitely check out Devil's Hole.
This was just amazing. Breath taking close up views of the rapids. There are steep steps that take you to trail and you have to climb them on the return trip. The hiking trail has some tough areas to get thru but it's well worth the trip. I would plan on at least an hour each way. Take water and...
I'm a native to the area, and pretty much hike devils hole on the reg. This is a perfect hike if you want to just get out and be in nature, see the gorge/whirlpools (its not a super long trail) The hike will start on the left, you will see the sign for devils hole trail, yes the "stairs" are...
It's a beautiful place to hike. We loved visiting in Autumn and look forward to visiting in other seasons as well. You should be careful if you have small children and if you're not really steady on your feet if you do the hike.
We did not plan this part of the trip but decided to take a ride before heading home and this was an experience I will surely never forget. Worth the short drive from the falls.
history is really neat- read up on it before you go. here is a clue: it is legend that the hole is a portal to the spirit world. a former president and indian chief had a chance meeting there.....
...however, I do recommend going to see this park after you've seen Niagara Falls, if there's time. This part of the river is post-Falls, but check out the beautiful jade color. Also, check out the sign on the property that states the history of the location, and the bloody massacre that took place there!
Devils Hole is a vortex or river whirlpool. Not a lot to see here, some construction obstruction. Best part is watching the river jet boats shooting through.
I have been to this park a few times and never tire of its beauty... Is a little hike down and up but can also Ben enjoy from on top if more novice... I take my two young kids and they do just fine with a little supervision. Bring a drink and snack and enjoy the beauty of nature


text:
A free way to build your virtual collection, make lists, and share them. It's your new home on Criterion.com.
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Raconteur. Mystic. Fabulist.
Featured Lists:James Agee's Criterion By Neil_McGlone
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The Innocents by Jack Clayton


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Victor Tin Cat Repeating Mouse Trap
Article # 41989
Online Availability: No Longer Available
Order Online Pick up In-Store for free
This item ships FREE to any of our Cabela's Canada locations for pick-up. Learn More
Product Description
Victor Tin Cat Repeating Mouse Trap
No winding or resetting. Catches up to 30 mice. No bait required. No-jam mechanism.


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Harrison was originally named for U.S. President William Henry Harrison and became the seat of Hamilton County in 1840. It was transferred to Chattanooga in 1870 due to its rapid growth.
Tennessee Vacation eGuide
The 2016 eGuide gives you instant access to Tennessee's irresistible attractions and destinations. Peruse venues online, then put in your order to get a free guide delivered to your doorstep.


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Let's see if we can figure out what's causing your symptoms.
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- Coma
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What causes coma and frequent urination? 2 possible conditions
See a list of possible causes in order from the most common to the least.
Diabetes insipidus (DI) is a rare condition that occurs when your kidneys are not able to conserve water. It results in extreme thirst for water and frequent urination. There are several types of DI, and they can ofte...
Hypercalcemia is a condition in which you have too much calcium in your blood.
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The pathogenesis of fibrotic lung disease involves the inability of proliferating alveolar type II cells (AT2) to differentiate effectively into type I (AT1) cells, leading to faulty epithelial repair, irreversible damage, loss of function, and fibrosis. The mechanisms that normally control this process are not fully understood, so potential regulatory molecules or pathways that may be altered in fibrotic pulmonary diseases have not been elucidated. We propose that the key to normal alveolar cell differentiation is the relative sulfation of the extracellular matrix (ECM) microenvironment underlying alveolar cell types. This in turn controls expression of two important differentiation factors: a member of the forkhead (Fox) family of transcription factors and specific wingless (Wnt) signaling pathways. These factors act in conjunction with expression and signaling of transforming growth factor ? (TGF?), which enhances Wnt signaling targets, to collectively drive the cell differentiation process and establish stable alveolar phenotypes. In this proposal, we will show that following proliferative events associated with re-epithelialization in the alveolus, there is a critical, dynamic balance between alveolar epithelial cells and their ECM microenvironment. This is significantly modulated by both fixed and soluble sulfated ECMs, whose downstream effects are to specifically enhance Wnt7a and Foxa1 expression, which act together with TGF? to regulate the shift from the AT2 phenotype and control AT1 cell differentiation. The hypothesis to be addressed is: Following DNA synthesis and cytokinesis, exposure of the daughter AT2 cell to high levels of sulfated ECMs triggers enhanced expression of Foxa1 and Wnt7a in parallel with increased TGF? expression and signaling, which converge to effectively drive differentiation of AT2 to AT1 cells. To address this hypothesis, we will utilize isolated AT2 cells from humans and normal as well as conditional gene knockouts and overexpressors from rodents in traditional and modified co-culture with human and rodent fibroblasts - important regulators of the AT2 cell microenvironment. Cells and ECMs will be selectively modified with specific enhancers or inhibitors of Fox expression, and TGF? and Wnt expression and signaling, and ECM composition. These results will serve as a contextural backdrop for examination of targeted molecules by protein and/or gene expression methods in a whole animal model of alveolar injury and fibrosis. Results of these studies are expected to provide essential information needed to better understand basic cell-cell and cell-ECM relationships in alveolar epithelial homeostasis as well as the mechanisms that steer the pathogenesis of fibrogenic change in the lung as a consequence of alveolar injury and/or disease.
Disease or environmentally-based toxic agents can damage or injure cells that line the internal surfaces of the lung, and how these cell repopulate themselves in large part determines whether the lung heals or not. To accomplish this, specific cells must divide and differentiate into other cells that carry out critically important lung-specific functions. Interruption of this process has serious consequences resulting in faulty repair and permanent damage to the lung and compromises function. This grant will define the specific mechanisms that control this process, and in doing so, enable the development of new and innovative ways to promote the healing process in injured lungs.
|Dush, Michael K; McIver, Andrew L; Parr, Meredith A et al. (2011) Heterotaxin: a TGF-ýý signaling inhibitor identified in a multi-phenotype profiling screen in Xenopus embryos. Chem Biol 18:252-63
|Newman, Donna R; Walsh, Eric; Apparao, K B C et al. (2007) Fibroblast growth factor-binding protein and N-deacetylase/N-sulfotransferase-1 expression in type II cells is modulated by heparin and extracellular matrix. Am J Physiol Lung Cell Mol Physiol 293:L1314-20
|Gabr, Amir A; Reed, Mathew; Newman, Donna R et al. (2007) Alterations in cytoskeletal and immune function-related proteome profiles in whole rat lung following intratracheal instillation of heparin. Respir Res 8:36
|Newman, Donna R; Li, Cheng-Ming; Simmons, Rebecca et al. (2004) Heparin affects signaling pathways stimulated by fibroblast growth factor-1 and -2 in type II cells. Am J Physiol Lung Cell Mol Physiol 287:L191-200
|Evans, Michael J; Fanucchi, Michelle V; Baker, Gregory L et al. (2003) Atypical development of the tracheal basement membrane zone of infant rhesus monkeys exposed to ozone and allergen. Am J Physiol Lung Cell Mol Physiol 285:L931-9
|Li, Cheng-Ming; Newman, Donna; Cesta, Mark et al. (2003) Modulation of fibroblast growth factor expression and signal transduction in type II cells. Chest 123:429S
|Evans, Michael J; Van Winkle, Laura S; Fanucchi, Michelle V et al. (2002) Fibroblast growth factor-2 in remodeling of the developing basement membrane zone in the trachea of infant rhesus monkeys sensitized and challenged with allergen. Lab Invest 82:1747-54
|Li, Cheng-Ming; Newman, Donna; Khosla, Jody et al. (2002) Heparin inhibits DNA synthesis and gene expression in alveolar type II cells. Am J Respir Cell Mol Biol 27:345-52
|Pagan, Ines; Khosla, Jody; Li, Cheng-Ming et al. (2002) Effect of growth factor-fibronectin matrix interaction on rat type II cell adhesion and DNA synthesis. Exp Lung Res 28:69-84
|Wang, Yiqiong; Sakamoto, Kaori; Khosla, Jody et al. (2002) Detection of chondroitin sulfates and decorin in developing fetal and neonatal rat lung. Am J Physiol Lung Cell Mol Physiol 282:L484-90
Showing the most recent 10 out of 21 publications


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Excessive levels of the hormone dihydrotestosterone (DHT) is a common cause of both hair loss and prostate problems for men.
Pumpkin seed oil contains many beneficial health nutrients and two in particular that are believed to provide protection against DHT damage. Here's how pumpkin seed oil can help maintain healthy hair and prevent male prostate enlargement.
If you're a man, regularly producing too much dihydrotestosterone in your body can cause hair loss and eventually male pattern baldness.
This page is designed to be a resource for where to find good pumpkin seed oil at the best price online. It covers the two main types – the Styrian version for culinary uses and the cold pressed oil, best used for its nutritional value and health benefits.
Styrian pumpkin seed oil, also known as kuerbiskernoel, is made by drying and low temperature roasting the seeds from the stripy green and yellow pumpkins from this traditional region of Austria.
Along with being a great tasting culinary oil, pumpkin oil is most commonly taken for preventing hair loss and prostate problems, due to its reported DHT blocking properties.
This page has some of the other most important pumpkin seed health benefits and problems it can help with.
Like the seeds, raw pumpkin seed oil can help improve skin tone and may be a beneficial supplement for many skin problems like acne, dry flaky skin, eczema and psoriasis.
Alongside the powerful antioxidant content, the high levels of natural fats would appear to be responsible for this effect.
Traditional Styrian pumpkin seed oil is made from lightly roasted pumpkin seeds that are pressed to extract a dark green oil. It has a rich and nutty flavor that makes a great salad dressing and healthy, flavorsome addition to many recipes.
Ahead is a look at all of the nutrition in pumpkin seed oil, whether you should choose roasted or raw, and the best dose to take it in for maximum benefit.


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National Grid ordered to pay KeySpan severance
Supreme Court Judge Vito DeStefano ruled that National Grid was on the hook for severance pay for 15 former employees of KeySpan Communications Corp.


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Defender Picks
February 25th
Uptown-St. Charles Route, 11AM
All-female group is one of Carnival's oldest krewes
Uptown-St. Charles Route, 12PM
1,300 men and women make up one of the most satirical and irreverent krewes in Mardi Gras
Mid-City Route, 4:15PM
One of the biggest and most extravagant parades, Endymion is long enough to last all night
One Eyed Jacks, 9PM
Bounce Queen moves 'dat azz
The Bombay Club, 8:30PM
Classic jazz trumpet
House of Blues, 8PM
Australian reggae rockers
SiriusXM Jam On Presents: Galactic
Tipitina's, 11PM
First-rate funk band is joined tonight by Stoop Kids
Hi-Ho Lounge, 11PM
Underground disco and rare groove dance party
Howlin' Wolf, 10PM
Beloved brass band takes the stage
Blue Nile, 7PM
The iconic Washboard Chaz takes a break from the Tin Men to lead this trio
February 26th
Uptown-St. Charles Route, 11AM
Celebrating it's 68th year, Okeanos is heavy on tradition
Uptown-St. Charles Route, 11:45AM
Yes, the Mid-City krewe is parading along the Uptown route
Uptown-St. Charles Route, 12PM
Thoth seeks to bring Carnival joy to the sick and infirm
Uptown-St. Charles Route, 5:15PM
Celebrating the God of wine, feasts, and general good times, Bacchus is one of the most anticipated parades
Rare Form, 4PM
NYC-based hot jazz, blues and swing
d.b.a., 6PM
Local trad jazz masters
Prytania Theatre, 6PM
Enjoy snacks, cocktails and more as the rich & famous vie for those golden statuettes ($25)
The Allways Lounge, 8PM
Weekly recurring dance lessons to live swing music (FREE)
Gasa Gasa, 10PM
European invasion from Swedish indie pop star LEON and UK-based R&B singer Jacob Banks ($15)
Howlin' Wolf, 10PM
Ivan & krewe bring da funk, joined by Miss Mojo
Big Chief Monk Boudreaux & John Papa Gros
d.b.a., 11PM
Golden Eagles Chief brings Mardi Gras Indian funk
Vaso, 11PM
Get Up, Get Down, Get Funky, Get Loose
Room 220
If only we didn't try to be bigger than our hearts with our hearts: An interview with Jenn Marie Nunes
Jenn Marie Nunes will publish her first full-length book, AND/OR, this spring with Switchback Books after winning the feminist press' inaugural Queer Voices contest, judged by Dawn Lundy Martin.
LSU Alums Hill and Backham Golden in NFL
The Saints' season is retro, evoking the paper bag era. And, LSU's 8-4 record was a disappointment to most Tiger faithful. However, the purple and gold still provided a reason to watch the NFL on a Sunday even when the struggling Saints are playing on Monday. LSU alumni and pro rookies Jeremy Hill and Odell Beckham, Jr. posted an impressive Sunday (12.14.)
Committees Dish Bowl: Wolf Pack, OSU, Tide Rolling to Dome, LSU to Nashville
Despite, a disappointing season for SoLa in both pro and college football, there are still bowl games to look forward to. LSU was gifted the opportunity to finish the season in style. The Ragin' Cajuns have found an appointment for their annual romp in da Dome, and it looks 'Bama will be back in town in 2015.
Orion Blasts Louisiana Back to Space
By Ashley Larsen
Today, millions of Americans watched as the Orion spacecraft was launched into the sky from the Cape Canaveral Air Force Station, but what most people didn't know is that it carried a lot of Louisiana with it. Both the capsule and a piece of the payload can lay claim to roots on the bayou.
SEC Joins Campaign Against Sexual Assault on Campus (Video)
The Southeastern Conference (SEC) actually involves much more than athletics. Today, the conference tooks steps to address one of the larger problems at any university. LSU and the 13 other SEC schools have partnered up with the White House's "It's On Us" campaign to fight sexual assault on campus. Today, the initiative rolled out a different kind of advertisement which will become a staple during Tigers' games.
Sunday Morning Quarterback
Takeaways from LSU's 30-27 Win Over Florida
LSU edged out 30-27 win in a nail biter against Florida on Saturday (10.12) night. The nail biter was LSU's first SEC win, and handed the troubled squad some momentum as they eye tough match ups against Alabama, Ole Miss, Arkansas, and Texas A&M in the weeks ahead. Top Freshman recruit Leaonard Fornette looked as if he is coming into his own as did the defense. QB Anthony Jennings did not.
Moving Murals in the Red Stick
By Ashley Larsen
#Iammidcity. Tonight, Baton Rouge MidCity is hosting a unique community art event to celebrate the people and the character of Mid City. LSU students, enrolled in the 2014 Mid City studio class, are creating the architectural mural with the help of several businesses in Baton Rouge as well as The Walls Project. Friday's (10.10) soiree will be focusing on receiving input from the community on the project as well as raising support for the project.
Out Tigered: LSU Throttled by Auburn 41-7
Defense Once Again Thwarted by Spread
LSU came into Jordan-Hare Stadium nine point underdogs against the Other Tigers of Auburn. Freshmen Brandon Harris, Leonard Fournette, and Malachi Dupre were saddled with the weight of leading the Purple & Gold against the SEC West team. The game was daunting but filled with hope for the future. That hope was quickly dashed and LSU was throttled 41-7. It is going to be a long fall in Baton Rouge.
Brazile-an Facts: LSU to House Politico's Papers
Time to see how competitive James Carville is. Fellow local political strategist Donna Brazile just donated 32 boxes of political memorabilia documenting her involvement and career in Democratic politics to LSU libraries. A proud Kenner native and graduate of LSU, she was the first African American to campaign for the presidency and managed Al Gore's presidential bid in 2000.
Miss'd Opportunity: QB Controversy as LSU Beaten By Unranked Miss St 34-29
For weeks, Saturday's game at Tiger Stadium has been billed as the "real home opener." The 34-29 result bodes poorly for the remainder of the season. Despite a late surge to make score close, LSU was thoroughly outplayed. More worrisome, a resounding exclamation point was placed on the quarterback controversy.Leonard Fournette was not a factor, but Josh Robinson certainly was. Les Miles and Cam Cameron left only questions but Mississippi State's Dan Mullen answered them all.
Dead Huey Long, Emma Boyce, Elizabeth Davas, Ian Hoch, Lindsay Mack, Anna Gaca, Jason Raymond, Lee Matalone, Phil Yiannopoulos, Joe Shriner, Chris Staudinger, Chef Anthony Scanio, Tierney Monaghan, Stacy Coco, Rob Ingraham,
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Welcome to our Intentional Community of Health Seekers!
Sep 27, 2016 · 9:00 AMHolistic skin clinic with Dr TDr. Adiel Tel-Oren MD, DC, LN, CCN, DABFM, DACBN, FABDA, Nutritional, Environmental & Functional Medicine Holistic Skin Treatment Clinic Remove disturbing lesions, tags,... Learn more
Sep 26, 2016 · 7:00 PMDo I have cancer? Lecture By Dr. TPotluck & lecture 7pm $5 love donation Do I have cancer? Lecture by Dr. T This life-saving lecture will address the following topics: am I really at risk? Why does the... Learn more
Apr 24, 2016 · 4:00 PMViktoras Kulvinskas Vitality & LongevityViktoras Kulvinskas is Back! ! ! Co-Founder with Dr. Ann Wigmore of the Hippocrates Health Institute Vitality and Longevity Youthing Lecture Join us for this lecture by... Learn more
Apr 14, 2016 · 5:30 PMThe China Study , T Colin Campbell in Ft Myersthis event is full, no rsvp are being taken at this time. REPOST RSPV TODAY , FILLS UP FAST T Colin Campbell author of The China Study & Nelson Campbell RSVP NOW for T.... Learn more
Apr 12, 2016 · 9:00 AMHolistic Skin Clinic with Dr. Thttp://www.doctortevents.com/index.php/skin-clinics-appointments/southeast-skin-clinics/4-12-naples IF WE CAN GET A ROOM CONFIRMED AT DR. JOEL YING'S OFFICE, WE WILL... Learn more
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Mangano creates economic recovery task force
The task force, comprised of leaders in business, health care, banking, retail, technology, infrastructure and education, will focus on providing information and guidance to local elected officials as they develop executive orders to aid and protect small business owners.


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Home > LRR > Vol. 1 > No. 16 (1990)
Article Title
[Excerpt] Earlier this year, OCAW Secretary-Treasurer Anthony Mazzocchi, one of the "founding fathers" of the OSH movement in the late 1960s, started a new publication that embodies and seeks to further the growing coalition of OSH and environmental activists. We reprint here Mazzocchi's Publisher's Introduction to the first issue of New Solutions.
Recommended Citation
"Labor Bookshelf,"
Labor Research Review:
Vol. 1:
16, Article 1.
Available at: http://digitalcommons.ilr.cornell.edu/lrr/vol1/iss16/1


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|Jake Roberts <j...@quantum4d.com>
|Multi-Value Properies in SystemView XML
|Thu, 11 Oct 2007 21:12:57 GMT
Apologies if this question has been answered elsewhere; I've poked around and haven't seen anything. I feel like I'm missing something basic. I'm trying to round-trip repository data to and from System View XML. But there's a problem: When a multi-valued property that happens to have only one value is exported to XML (System View), it becomes a single-valued property on re-import of the same file. Consulting the JCR spec, it looks like no provision is made for recording the multiplicity of a property in System View XML. You get the name, the type, and the values and that's it. When I import the same XML file, it appears that the importer decides whether a property is single or multi-valued based on the number of value elements present for that property in XML. And as far as I can tell, there's no other way it could work. The information necessary to tell a single-valued property from a multi-valued property with a single value isn't present. Or am I confused? In any case, the practical upshot is that I get ValueFormatExceptions on properties that my application expects to be multi-valued, as they were prior to export and re-import. Any suggestions on how to correctly handle round-tripping of multi-valued props via System View XML? Thanks, - Jake -- View this message in context: http://www.nabble.com/Multi-Value-Properies-in-SystemView-XML-tf4610005.html#a13164867 Sent from the Jackrabbit - Users mailing list archive at Nabble.com.
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With his reformist government under fire from all sides of the political spectrum, Mr Yeltsin denounced the newly formed National Salvation Front as a grave danger to Russia's young democracy and said it should be disbanded immediately. The Front, which groups military officers, former Communists and politicians of the extreme right, held its founding congress in Moscow last weekend and elected a leadership dedicated to Mr Yeltsin's removal.
'The Front calls for the overthrow of the lawful authorities, is destabilising society, and is setting people against each other,' Mr Yeltsin told Russian diplomats. 'This is not permissible, and urgent measures must be taken without ado. It is a terrible threat, but the West doesn't yet understand it.'
As Mr Yeltsin spoke, a fresh challenge emerged to the liberal wing of Russian politics when security force units surrounded the offices of Izvestia, a newspaper firmly in the democratic camp. The units belonged to a 5,000- strong guard loyal to Ruslan Khasbulatov, the speaker of the conservative- dominated parliament and a frequent critic of Mr Yeltsin.
Parliamentary leaders sent the units to enforce their decision last week to place the newspaper under the legislature's control and silence its criticisms of Mr Khasbulatov and the conservatives. 'I would not be surprised if they stop us entering the building tomorrow,' said Nikolai Bodnaruk, the deputy editor.
Liberal MPs fear that Mr Khasbulatov's force poses a threat to democracy because it is answerable neither to the Interior Ministry nor to Mr Yeltsin. They say its existence is all the more ominous in the light of the virtual state of war that the Front and other groups have declared on Mr Yeltsin.
Conservatives in the parliament threw down a challenge to Mr Yeltsin last week by blocking his attempt to delay a meeting of the supreme legislature, the Congress of People's Deputies. They voted to convene the Congress on 1 December and made clear they would use the occasion to press for the dismissal of several reformist ministers.
Prominent democrats, including Yelena Bonner, Andrei Sakharov's widow, voiced their alarm at the rising conservative tide in a public appeal which warned that opposition forces would not shrink from provoking a civil war to achieve their ends. Accusing the Communists and right-wingers of whipping up 'social and nationalistic hysteria', the democrats said hostility was being fanned against Jews, Ukrainians, Balts, Georgians, Armenians and any Russian deemed to be unpatriotic.
'The maturing coup need not take the form of an open putsch. A quiet, creeping revenge of the apparatchiks and nomenklatura is being prepared, with a view to wresting Russia from the civilised world . . . To be or not to be for Russia's reforms means today to be or not to be for Russia itself,' said the appeal signed by Mrs Bonner and other liberal politicians and intellectuals.
But one National Salvation Front activist, Alexander Medvedev, responded: 'We should unite to oppose all domestic and foreign provocations. Otherwise, mortars and sub-machine-guns will start to talk in Moscow and St Petersburg.'
- More about:
- Country Of Georgia
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Testicles so massive they could be used as a flotation device and can save lives.
Seth is drowning Brian! Pull off your pants! RESCUE BALLS!
by TomKVideo March 23, 2009
The Urban Dictionary Mug
One side has the word, one side has the definition. Microwave and dishwasher safe. Lotsa space for your liquids.Buy the mug
The Urban Dictionary T-Shirt
Smooth, soft, slim fit American Apparel shirt. Custom printed. 100% fine jersey cotton, except for heather grey (90% cotton).Buy the t-shirt


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logo and visual identity
This project has been awarded to geraldine1983 for £70 GBP.Get free quotes for a project like this
Project Budget£70 GBP
Total Bids1
Project Description
We are a London based design duo looking for a logo design and identity for our start up Ladies footwear brand. We are looking for something that reflects our love and fashion and the ethos of our brand. Our principal mission is flats with and edge, our work is fashion forward, reflecting catwalk trends and the demands on the feet of modern life. We are looking for someone to assist us to create a visual identity we can use across web and physical product.
As we are a design team ourselves, we hope that this should be an interesting assignment.
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Manage Bitcoin addresses
JavaScript component to handle Bitcoin addresses.
See this article for more details: bitcoin address.
npm install --save btc-address
var Address = var binConv = var hash160 = "3c176e659bea0f29a3e9bf7880c112b1b31b4dc8";var address = ; console //16UjcYNBG9GTK4uq2f7yYEbuifqCzoLMGS
Most of the code from Stefan Thomas in https://github.com/bitcoinjs/bitcoinjs-lib with modifications from Roman Shtylman
(MIT License)


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Falling Cloudberries: A World of Family Recipes by Tessa Kiros, includes international recipes like Prego Rolls; Herrings Marinated in Vinegar with Dill, and Allspice; and Kolokassi.
Serves 4
This is how my mother makes her herrings. There are many ways to marinate and serve herrings and these are my favorite, marinated in vinegar, some sugar, carrots, onions, dill, and allspice. I also like them done with tomato and onion. They need to stay in their marinade for about three days before you eat them. Keep the jar in the fridge and make sure that the herrings are immersed in the liquid. They will keep for about a week in the fridge and the flavor will get stronger. I use lightly smoked salted herrings and you can also use unsmoked if you prefer. You might also like to add a dried red chili to your jar. These herrings are good served with room temperature potatoes that have been boiled with salt and dill stalks, or rye bread.
Rinse the herrings and soak them overnight in cold water, changing it a couple of times.
To fillet a herring, cut off the head and tail and then open the fish out flat, skin side up. Using your thumb, press down firmly along the backbone. This will nearly release the bones from the flesh. Turn the fish over and use scissors to snip through the backbone at the head and tail. Pull away the backbone, working toward the tail end. Remove any stray bones with your fingers or tweezers. Wash the fish and pat it dry. Cut the herring fillets into 1-inch strips.
Meanwhile, boil the vinegar, sugar, peppercorns, and 1 cup water in a small pan for a few minutes, stirring to make sure the sugar has dissolved. Remove from the heat and add the allspice and bay leaves. Leave to cool down completely.
Layer the herring strips in jars with the dill, onion rings, and carrots. Pour the cooled liquid into the jars, put on the lids tightly, and keep refrigerated. Marinate for three days (or at least 24 hours if you're in a hurry) before serving. The herrings are also good drained of vinegar and served on a plate with a drizzle of olive oil.
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Tulane 1L Served 12 Years in Prison for Second-Degree Murder of College Prof
Posted Sep 16, 2011 12:59 pm CDT
First-year Tulane law student Bruce Reilly has worked as a community activist and organizer, written plays and authored a blog. But he's getting attention for his criminal past.
Reilly, 38, served 12 years in prison in Rhode Island after pleading no contest to the second-degree murder and robbery of community college professor Charles Russell, the New Orleans Times-Picayune reports. Reilly had been hitchhiking in 1992 when Russell picked him up and took him to his home. There was a fight, the Times-Picayune says, and Reilly fatally stabbed Russell and stole his car and credit cards.
Above the Law broke the story to a widespread audience earlier this week. But Reilly had already revealed his past on his own blog, Unprison, after realizing that his classmates were talking and evidently finding his blog by Googling "Bruce Reilly murder." In response, he offered a post and a picture of a T-shirt with the words, "F— Google, ask me."
"Some of you may be reading this article subsequent to a Google search," he wrote in a post that has since been removed. Above the Law posted a paragraph. "Perhaps you are the person whose Friend Request I ignored, as you may have tried that route to know me: look at all my photos, read my info, check my Wall, and know me as if we were tight since grade school. We live in a passive-aggressive culture of curiosity and fear. The former is an admirable trait, while the latter is what allows us to be controlled. … Lets cut to the chase: I killed a man 19 years ago."
Reilly told the Times-Picayune he has tried to make up for the crime by living his life helping other people. He was a jailhouse lawyer in prison and wants to use the law to improve the criminal justice system. One of Reilly's friends told Above the law he is "the nicest guy you'll ever meet," he's articulate, and he's good at "crystallizing arguments."
Law dean David Meyer gave a statement to both publications. "We evaluate each law school applicant as an individual, taking into account all available information bearing on their character, life story and academic qualifications. Our admission process also allows for exceptional circumstances if the prospective student's experience and background will contribute to his and his peers' study and appreciation of various aspects of the law," Meyer said in the statement to the Times-Picayune.
May the US Kill Rank-and-File Terrorists in Yemen and Somalia? Administration Lawyers Are Split
I Was Tom Cruise Character in 'A Few Good Men,' Four Lawyers Say
We welcome your comments, but please adhere to our comment policy and the ABA Code of Conduct.


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Three creative young musicians in New York Tsahar, Mat Maneri and Black in a trio of warmly orchestrated free improv with witty restraint in extended conversation.
Tsahar / Maneri / Black
Label: Hopscotch Records
Released in: USA
"Whether sparse or dense, light or heavy, stuttering or gliding, the nine untitled tracks on Jam feel like a natural progression. Something of a summit for these three out jazz improvisers, the recording unfurls like a series of open conversations might extend to tell a story.
That's appropriate given these players' exquisite control of their instruments and their preference for listening and responding, rather than shooting from the hip. And given that each of the nine untitled tracks tends to be an encapsulated entity, they unfold like chapters down a musical path. There's almost no melody in the usual sense here, but that doesn't hinder the flow at all.
Assif Tsahar's real strength lies in his ability to coax an extremely broad range of timbres from his instruments, in this case the tenor saxophone and bass clarinet. His playing is rarely clean; instead of handling the horn "correctly," he drifts up and down around notes, coloring them with breath and overtones. The depth of his horns on this date is appropriately matched with Mat Maneri's 5-string violin, which stretches down into viola territory and quite often sounds like a cello. All that warmth makes the combination seem more human and better connected. And it's a pleasure to hear quick-witted (and usually quick-handed) drummer Jim Black in this setting, mostly channeling his usual flying sparks into a burning glow.
The first track on Jam sounds like the musicians are sitting down, getting comfortable, and settling into a rhythm. As the recording continues, the three players engage in short, halting interchanges, closely spaced without overcrowding. They sit back, introducing more space within and between each other's notes. As time passes the overall tenor of the record has been established: darkly clouded, deliberate, and often ominous. A brief wakeup call midway through marks a spike in energy where musical phrases crowd together in a more jumpy fashion, but then it's right back to more quiet brooding, and finally a gentle flush of dissonant waves closes things out.
Restraint and coherence are the key factors here. The first quality means the music consistently skirts overstatement, the second means it still spans a range and tells a story. The title of the record (in either culinary or musical senses) is somewhat ironic, though. This jam is more black currant than strawberry, served with more deliberate intent than freewheeling abandon."-Nils Jacobson, All About Jazz
See all items in the Hopscotch Records category
Related Categories of Interest:
Improvised Music
NY Downtown & Jazz/Improv
Hopscotch Records
Trio Recordings
Get additional information at All About Jazz
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In Stock
Shipping Weight: 2.00 units
Quantity in Basket: None
Label: Hopscotch Records
Catalog ID: HOP 21
Squidco Product Code: 2408
Format: CD
Condition: New
Released: 2003
Country: USA
Packaging: Cardstock Gatefold Sleeve
Assif Tsahar-tenor sax, bass clarinet
Mat Maneri-5 string electric violin
Jim Black-drums
Highlight an artist name or instrument above
and click here to Search
Track Listing:
1. Part One 6:40
2. Part Two 4:57
3. Part Three 7:02
4. Part Four 6:07
5. Part Five 4:24
6. Part Six 5:41
7. Part Seven 3:34
8. Part Eight 5:11
9. Part Nine 8:11


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Polygamy in Islam: what a good idea. A man or woman can have up to four wives or husbands at any one time. I wouldn't fancy it myself, but if everybody's happy with the arrangement ....
Sorry, the Sharia people have just been on. Apparently – and yes, I know this is bizarre – in Muslim law it only applies to men taking wives, not the other way round. How on earth can that be? That was the question I was longing to hear in Jemima Khan and the Part-Time Wife. The New Statesman journo conducted a sensitive and revealing exploration of Muslim polygyny, as I think we should refer to it, and a neutral investigation was always going to get further than anything judgemental. But once, just once, I wanted her to confront one of its more enthusiastic supporters (and they weren't just men) with a baffled "What the –?"
Though there was lots of talk about it being a lifestyle choice for working divorcees, and about how the man is bound by law to treat all his wives equally, the experience of "Aisha" (not her real name), who was "married" in her living room, seemed not untypical. There were teething problems, she reported, such as the fact that hubby had omitted to tell Wife No 1 about the new deal.
Perhaps the most depressing line was the observation by a Muslim woman activist that young men see it as a way of asserting their Islamic identity. For all Khan's admirable even-handedness I was left with the overwhelming feeling that it's a social evil that should end, now.
Thirty or 40 years ago on Nationwide, an item on polygamy might have been preceded by something about the Troubles and followed by a humorous animal item. In the excellent Britain in a Box, which recalls TV landmarks, Paul Jackson looked at the teatime magazine that spawned a host of luminary careers. Sue Lawley's was one, and she delivered the definitive verdict. It was, she said, the perfect example of the Reithian mission to inform, educate and entertain. "I'd like to think Lord Reith would have approved," she said. "Even of the skateboarding duck."
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FlexSol Solutions designs its own custom, stand-alone solar control and telecommunication systems. From MPPT and power conversion to BMS and telecommunication.


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This is your resource to discuss support topics with your peers, and learn from each other.
I recently upgraded from the Torch to Q10. Previous advertising of the Q10 and on BlackBerry's website, I should be able to do a BBM Video Chat on my mobile network, right? But why can't I? I can only do a BBM Video Chat when I'm in a wi-fi area. Please help.
I called AT&T and advised them of the problem but AT&T referred me or transferred me to BlackBerry. I spoke with a BlackBerry service rep (male), who told me that BBM Video Chat only works on wi-fi. I told him but BlackBerry's website on Q10 BBM Video Screen Share shows and tells that it can work on mobile network, which I should be able to turn On or Off. He said no it's not a feature. Holy Moly. What's the truth?


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The major histocompatibility complex (MHC) class II locus is strongly associated with the risk of type 1 diabetes, and tissue specificity of the autoimmunity causing diabetes is likely to be determined by the trimolecular complex composed of an MHC molecule, an antigen, and a T cell receptor (TCR). We hypothesize that the interactions between components of this trimolecular complex, all of which are encoded in the germline, determines the nature of T cells involved in the development of type 1 diabetes. Targeting of an insulin B chain 9-23 amino acid peptide (insulin B:9-23) is highly likely to be an essential determinant in the initiation of islet inflammation in the spontaneous diabetes animal model, NOD mouse. We recently discovered that TCRs containing the germline-encoded variable gene (Vgene) sequence called "TRAV5D-4" play a critical role to induce anti-islet autoimmunity via the recognition of insulin B:9-23 peptide. Thus, the trimolecular complex consisting of the insulin B:9-23 peptide and TRAV5D-4 TCR alpha chain plays a key role in developing anti-islet autoimmunity;however, how T cells expressing TRAV5D-4 TCRs contribute to the initiation and development of the disease remains to be elucidated. Given evidence that the DQ8 diabetes- susceptible HLA class II molecule is an ortholog of NOD I-Ag7 presenting the insulin B:9-23 peptide and that T cells expressing TRAV13-1 (human ortholog of TRAV5D-4) TCR alpha chains dominantly exist in the pancreas of a type 1 diabetes patient having DQ8, the ultimate goal of this proposal is to verify a proof of concept that insulin targetig by a specific germline-encoded TCR Vgene motif plays a critical role in the development of islet autoimmunity. In this proposal, we aim to determine the molecular mechanism of how TCRs, in particular those containing TRAV5D-4, target the critical peptide, insulin B:9-23, to initiate isle inflammation using the NOD mouse model (Aim 1), and to determine whether T cells expressing TRAV5D-4 are essential for diabetes development in NOD mice (Aim 2). If the development of anti-islet autoimmunity is completely suppressed in the absence of TRAV5D-4, targeting only T cells expressing such essential TRAV genes will enable us to develop a robust immunotherapy with the minimum of side effects. Finally, we will pursue the hypothesis that there is a conceptually similar interaction in the human trimolecular complex consisted of the insulin B:9-23 peptide and TRAV13-1 TCR Vgene motif underlying susceptibility to human type 1 diabetes (Aim 3). Findings from this proposal will provide a deeper understanding of the principles underlying the initiation of islet autoimmunity via the interaction within the insulin trimolecular complex, which will ultimately to be applied to design antigen-based immunodiagnostic and immunotherapeutic clinical studies for type 1diabetes in humans!
The proposed research will enhance our understanding of the mechanism how our own tissues are destroyed by the immune system and ultimately why autoimmune diseases occur. The knowledge gained by this proposal will lead us to develop therapies to prevent and cure autoimmune diseases such as type 1 diabetes.
|Bettini, Maria; Blanchfield, Lori; Castellaw, Ashley et al. (2014) TCR affinity and tolerance mechanisms converge to shape T cell diabetogenic potential. J Immunol 193:571-9


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Julie is a pretty blue (gray) and white girl. She likes attention and will cuddle in your lap. She gets along with other cats but wouldn't mind being the only princess in the castle. Her fur is very soft.
Julie's adoption fee is $50.00 which includes up-to-date shots, FeLV test (she's negative) and she's already spayed. She is litterbox trained.
To meet this kitty or for more information, please contact us at (850)377-2132, or email us at firstname.lastname@example.com. Or you can fill out our online cat adoption application on our website ecaaFL.org. There is a link on the top of the home page. Click on "Fill in", you don't have to register.
We are always in need of foster homes. If you find a kitty or dog and are willing to foster it - we can help you find it a furever home. Can't foster or adopt right now, help socialize kittens. The more people the kittens are exposed to the better is for them. We can always use volunteers. Work from home, work directly with animals, or work non-directly with animals helping us raise money or distributing fliers.
PLEASE, PLEASE, PLEASE spay or neuter your pets! Escambia County pound puts down over 1,000 animals a month! Through spay/neuter we can reduce that number.
Thank You!
Your message has been sent to Emerald Coast Animal Allies.
You'll receive a copy, too, at to help you keep track of which pets you've inquired about, and which shelters and rescues you've emailed.
NOTE: Some shelters have physical locations you can visit; some of these shelters may only have pets for a limited time, so please do not wait for a reply—just go visit the shelter! Other organizations are rescue groups run by busy volunteers who may take a while to reply. You can find information about the shelter or rescue group caring for this pet, and their adoption procedures, on the pet's details page on Adopt-a-Pet.com.


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There are several new eCoupons available on SavingStar. Remember these coupons are independent of all other coupon sources so go ahead and activate all of these for the month!
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Quote:for the vast ammount of kata 'step', however sliding motion is extremly important in karate and appears in several parts of kata.so the awnser IMO is both sliding and stepping have their uses!
Quote:Sliding doesn't mean your feet must always touch the ground. It's always preferable to raise your feet only as much as is needed because this will reduce your up-&-down movement. You want all your momentum going forward (or any other direction) to enhance power.Have you ever watched an Olympic hurdler compared to an average person jumping over hurdles? The hurdler's head remains on the same plane whether running or clearing the hurdle. The average person's head goes up-&-down. An exagerated but valid analogy.
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Let us know when your receive great advice so we can thank our lawyers and point others with similar questions in the right direction.Got it!
i got fired because i failed a random drug test can collect unemployment
Maybe. Using illegal drugs can be considered misconduct and your employer can fire you for it.
However, EDD (California Employment Development Department) has an exception for drug dependence. If you enter a rehabilitation program (this can include medically-supervised outpatient programs), you may be able to collect unemployment benefits.
You may not think you have a drug problem, but consider this: you knew your employer might randomly test you, but you used drugs anyway, and it got you fired. To me, that sounds like a problem.
Please understand that this is a general discussion of legal principles by a California lawyer and does not create an attorney/client relationship. It's impossible to give detailed, accurate advice based on a few sentences on a website (and you shouldn't provide too much specific information about your legal matter on a public forum like this site, anyway). You should always seek advice from an attorney licensed in your jurisdiction who can give you an informed opinion after reviewing all of the relevant information.
You may be ineligible for unemployment benefits as a result of the failed drug test pursuant to California UI Code Section 1256.4. However, you should nonetheless submit your benefits request and go through the process to force a final determination on the issue based on the reasons you provide.
The response given is not intended to create, nor does it create an ongoing duty to respond to questions. The response does not form an attorney-client relationship, nor is it intended to be anything other than the educated opinion of the author. It should not be relied upon as legal advice. The response given is based upon the limited facts provided by the person asking the question. To the extent additional or different facts exist, the response might possibly change.
Post a free question on our public forum.Ask a Question
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|Property type
|Minimum Stay
|1 - 7 nights
Every day will feel like summer at the tranquil Summer Breeze Condominiums! This 3 story, classically designed condominium offers you the chance to enjoy a quiet and relaxing vacation with nothing but the peaceful sea breeze outside your windows. Each spacious unit has a private balcony to provide you with breathtaking views of Florida sunsets.
And when you're ready to sink your feet into the sugary sand of the world's finest beaches, all you have to do is cross the street and you're there. The inviting pool is complete with plenty of lounge chairs and umbrellas, lovely landscaping, a hot tub and showers for a sand-free retreat. And to end a perfect day in the sun, gather the family around for a cook-out!
Or if you don't feel like cooking, there are several appetizing restaurants waiting to heat up your taste buds all within walking distance.
Summer Breeze is located in the heart of Destin so the entertainment opportunities are overwhelming! Outdoor malls, movie theatres, hundreds of eateries, arcades and award winning golf courses are all just minutes away
This condo rents weekly from Saturday to Saturday during Spring Break. Over the 4th of July holiday we require a weekly stay.
Located in Miramar Beach, Florida, Newman-Dailey is one of the premier vacation rental, property management, real estate sales and association management companies. For more than 30 years, Newman-Dailey has been welcoming guests to the beaches of South Walton and Destin, Fla. Recognized for excellence, integrity and professionalism, Newman-Dailey consistently receives the "Certificate of Excellence" for positive reviews on TripAdvisor and earned the BBB's 2015 Torch Award for Marketplace Ethics and was voted "Best Vacation Rental Company" and "Best Property Management Company" by the readers of Emerald Coast Magazine. And according to the Emerald Coast Association of Realtors (ECAR), Newman-Dailey's Real Estate Division consistently ranks among the top 10 percent of real estate companies along the Emerald Coast for sales. For more sales or rental information, call 850.837.1071, or visit online at DestinSales.com or DestinVacation.com.
Seasonally Heated Swimming Pool - Check for Dates
Condo was perfect. Kitchen was stocked well. Furniture and bed were very comfortable. Loved the fact there was no carpet. It smelled and looked very clean. Plenty of bedding and bath towels was a nice thought. There were alot of little things noticed that let us know alot of thought went into preparing condo for guests. ND was, as last time, exceptional. Shannon and Mike.


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Joomla Website Developer and Graphic Designer
This project was successfully completed by khalilshow for $1200 USD in 15 days.Get free quotes for a project like this
Project Budget$750 - $1500 USD
Completed In15 days
Total Bids48
Project Description
Looking for an experienced Joomla developer and web designer to develop a microsite that is separate to the company website but will also link to it.
A joomla template will be provided and needs to be customised and tailored to the company's requirements.
The microsite and design needs to be SEO friendly and the designer needs to have knowledge of SEO.
Candidate must have experience in joomla development, web designing, graphic designing and be advanced in english. Meetings via skype are essential.
Include the term 'Paradise' in a PM otherwise your application will be rejected.
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text:
A Study to Compare BMS-936558 to the Physician's Choice of Either Dacarbazine or Carboplatin and Paclitaxel in Advanced Melanoma Patients That Have Progressed Following Anti-CTLA-4 Therapy (CheckMate 037)
This study is ongoing, but not recruiting participants.
Bristol-Myers Squibb
Information provided by (Responsible Party):
Bristol-Myers Squibb
ClinicalTrials.gov Identifier:
First received: November 2, 2012
Last updated: January 5, 2017
Last verified: October 2016
- Full Text View
- Tabular View
- No Study Results Posted
- Disclaimer
- How to Read a Study Record
The purpose of the study is to compare the response rate and overall survival of patients taking BMS-936558 to those taking study physician's choice of either Dacarbazine or Carboplatin and Paclitaxel
Unresectable or Metastatic Melanoma
Biological: BMS-936558
Drug: Dacarbazine
Drug: Carboplatin
Drug: Paclitaxel
Phase 3
|Study Type:
|Study Design:
|Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Open Label
Primary Purpose: Treatment
|Official Title:
|A Randomized Open-Label Phase 3 Trial of BMS-936558 (Nivolumab) Versus Investigator's Choice in Advanced (Unresectable or Metastatic) Melanoma Patients Progressing Post Anti-CTLA-4 Therapy
Resource links provided by NLM:
MedlinePlus related topics: Melanoma
Drug Information available for: Dacarbazine Paclitaxel Carboplatin NivolumabU.S. FDA Resources
Further study details as provided by Bristol-Myers Squibb:
Primary Outcome Measures:
- Estimate the Objective Response Rate (ORR) in BMS-936558 (Nivolumab) treatment group [ Time Frame: 18 months ]ORR is defined as the number of subjects with a Best Overall Response (BOR) of complete response (CR) or partial response (PR) divided by the number of randomized subjects
- Compare Overall Survival (OS) of BMS-936558 (Nivolumab) to investigator's choice in subjects with advanced melanoma [ Time Frame: 23 months ]Overall Survival (OS) is defined the time between the date of randomization to the date of death
Secondary Outcome Measures:
- Progression-free survival (PFS) [ Time Frame: 23 months ]PFS is defined as the time from randomization to the date of the first documented progression or death due to any cause, whichever occurs first
- Programmed death-ligand 1 (PD-L1) expression [ Time Frame: 23 months ]To evaluate whether PD-L1 expression is a predictive biomarker for ORR and OS by testing the interaction between PD-L1 expression and treatment arms
- Health Related Quality of Life (HRQoL) [ Time Frame: Baseline (Day1) and 23 months ]HRQoL will be measured by mean changes from screening/baseline in the EORTC QLQ-C30 global health status/QoL composite scale and by mean changes from screening/baseline in the remaining EORTC QLQ-C30 scales in all randomized subjects
|Estimated Enrollment:
|Study Start Date:
|December 2012
|Estimated Study Completion Date:
|September 2018
|Primary Completion Date:
|February 2016 (Final data collection date for primary outcome measure)
|Assigned Interventions
Experimental: BMS-936558 3 mg/kg (IV)
BMS-936558 3 mg/kg solution for injection by intravenous (IV), every 2 weeks until documented disease progression, discontinuation due to toxicity, withdrawal of consent or the study ends
|Biological: BMS-936558
Active Comparator: Investigator's Choice (Dacarbazine or Carboplatin+Paclitaxel)
Dacarbazine: 1000mg/m2, Powder for IV solution, IV, every 3 weeks until documented disease progression, discontinuation due to toxicity, withdrawal of consent or the study ends
Carboplatin: Area under the concentration-time curve (AUC) 6, solution for injection, IV, every 3 weeks until documented disease progression, discontinuation due to toxicity, withdrawal of consent or the study ends
Paclitaxel: 175 mg/ m2, solution for injection, IV, every 3 weeks until documented disease progression, discontinuation due to toxicity, withdrawal of consent or the study ends
Drug: Dacarbazine
Other Names:Drug: Carboplatin
Other Names:Drug: Paclitaxel
Other Name: Onxol
|Ages Eligible for Study:
|18 Years and older (Adult, Senior)
|Sexes Eligible for Study:
|Accepts Healthy Volunteers:
For more information regarding BMS clinical trial participation, please visit www.BMSStudyConnect.com
Inclusion Criteria:
- Men & women ≥ 18 years of age
- Eastern Cooperative Oncology Group (ECOG) performance status (PS) 0-1
- Histologically confirmed Stage III (unresectable)/Stage IV melanoma
- Measurable disease by computed tomography (CT)/magnetic resonance imaging (MRI) per Response Evaluation Criteria in Solid Tumors (RECIST) 1.1 criteria
- Objective evidence of disease progression (clinical or radiological) during or after at least 1 (V600 Wildtype) or at least 2 (V600 mutation positive) prior treatment regimens
- Pre-treatment fresh core, excision or punch tumor biopsy
- Archival Formalin-fixed paraffin-embedded (FFPE) tumor material if available
Exclusion Criteria:
- Any treatment in a BMS-936558 (Nivolumab) trial
- Subjects with condition requiring systemic treatment with either corticosteroids (> 10mg daily prednisone/equivalent) or other immunosuppressive medications within 14 days of study drug administration
- Active, known or suspected autoimmune disease
- Unknown BRAF status
- Active brain metastasis or leptomeningeal metastasis
- Ocular melanoma
- Prior therapy with anti programmed death-1 (anti-PD-1), anti programmed death-ligand 1 (anti-PD-L1) or anti-programmed death-ligand 2 (anti-PD-L2)
Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.
Please refer to this study by its ClinicalTrials.gov identifier: NCT01721746
Show 94 Study Locations
Please refer to this study by its ClinicalTrials.gov identifier: NCT01721746
Show 94 Study Locations
Sponsors and Collaborators
Bristol-Myers Squibb
|Study Director:
|Bristol-Myers Squibb
|Bristol-Myers Squibb
More Information
Additional Information:
Publications automatically indexed to this study by ClinicalTrials.gov Identifier (NCT Number):
Additional relevant MeSH terms:
ClinicalTrials.gov processed this record on February 28, 2017
Additional Information:
Publications automatically indexed to this study by ClinicalTrials.gov Identifier (NCT Number):
Weber JS, D'Angelo SP, Minor D, Hodi FS, Gutzmer R, Neyns B, Hoeller C, Khushalani NI, Miller WH Jr, Lao CD, Linette GP, Thomas L, Lorigan P, Grossmann KF, Hassel JC, Maio M, Sznol M, Ascierto PA, Mohr P, Chmielowski B, Bryce A, Svane IM, Grob JJ, Krackhardt AM, Horak C, Lambert A, Yang AS, Larkin J. Nivolumab versus chemotherapy in patients with advanced melanoma who progressed after anti-CTLA-4 treatment (CheckMate 037): a randomised, controlled, open-label, phase 3 trial. Lancet Oncol. 2015 Apr;16(4):375-84. doi: 10.1016/S1470-2045(15)70076-8.
|Responsible Party:
|Bristol-Myers Squibb
|ClinicalTrials.gov Identifier:
|NCT01721746 History of Changes
|Other Study ID Numbers:
|Study First Received:
|November 2, 2012
|Last Updated:
|January 5, 2017
Additional relevant MeSH terms:
Neuroendocrine Tumors
Neuroectodermal Tumors
Neoplasms, Germ Cell and Embryonal
Neoplasms by Histologic Type
Neoplasms, Nerve Tissue
Nevi and Melanomas
Albumin-Bound Paclitaxel
Antibodies, Monoclonal
Antineoplastic Agents, Phytogenic
Antineoplastic Agents
Tubulin Modulators
Antimitotic Agents
Mitosis Modulators
Molecular Mechanisms of Pharmacological Action
Immunologic Factors
Physiological Effects of Drugs
ClinicalTrials.gov processed this record on February 28, 2017