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Solar Control Glass Tinting Co. eliminates the effects of sun over-exposure for residential and commercial properties throughout Northern California, from single-family homes to high-rise multiplexes. In addition to window tinting, it provides solutions for graffiti, eavesdropping security and safety issues. Other services include decorative interior and exterior glass applications.
Owner Rocky Burcham has seen the industry evolve from the days when tinting was done with liquids to the modern process of applying film. Solar film lets glare-controlled sunlight pass through windows while screening out heat and dangerous UV rays, he says. Bonding the film to the glass creates a barrier that protects against flying glass shards if the window is shattered. It also makes glass more difficult to break, which adds the element of security. Films with anti-graffiti surfaces protect against vandalism, while decorative films can mimic the appearance of expensive etched glass.
Solar Control Glass Tinting Co. provides free in-home estimates and samples of film. The company's website offers case studies from previous jobs and extensive information about its licensing and qualifications.
"Like our products, our personnel are top-quality. Many have been with us for 20 years or longer. All our employees take pride in a job well done. Excellent products and excellent service are the reasons so many Bay Area clients choose us again and again."
Serving Northern California
Window Tinting
Window Films
Graffiti Film
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Reduce Fade, Heat & Glare
Most consumers, designers and business owners have little experience with solar glass tinting, so do your homework before you buy.
When looking for a contractor for specialized services such as window tinting, it's important to educate yourself and find a company you trust. The only real way to accomplish that, says Rocky Burcham of Solar Control Glass Tinting Company, is...
"I would show them before and after pictures of what the windows look like on my shop and they look as good as new. All of the tinting did the trick to remove any scratches.""It is so easy to clean and to maintain. I was pleased with the price quote."
"They were very good about specifying different options depending on what your needs are.""They offered several options and they were prompt with delivery."
"I'd recommend them. They do good work.""They know what they're doing and they're punctual."
"For me, it was critical to reduce the light without having to buy new glass.""It is permanent and it is relatively reasonable. With care, it should be there for a long time."
"They are very reliable and I am happy with them.""They are very reliable."
"The tinting cuts down on the heat and the fading of the leather and fabric. And it's nice that it doesn't have that mirrored look. You can hardly see any difference looking at it from the outside.""It was so easy to work with them and they did such a nice job. I was very happy."
"I would recommend them.""They were on time, they were efficient, they were very responsive, and they did a clean job with the installation."
"Try them out. I'd recommend them.""They are thorough and they have a fairly reasonable price."
"They are a great company and they know what they are doing. I am very satisfied with their work, their performance, and their product.""There is nothing that particularly stood out to me because they're very good all around."
"I like the work they did and I've used them a few different times. I think the tinting is beneficial in terms of thermal control, privacy, and protection from glare.""I think they were very good and they stand behind their work. They said if there's any problem, they'd replace the whole window."
"I have recommended them to my sister. It was very simple to use them.""They were good at explaining my options, they were professional, and there were no surprises."
"They were very professional, very honest, and they do the job in a timely manner.""They did the job as promised."
"I have told several people how satisfied I am with their work. They do top-notch work.""I think I felt confident with their work, they use quality materials, and they are honest."
"They're very helpful in finding the right product for me.""Their honesty in not selling me a product that I didn't need."
"I thought they were very professional, and they did a good job.""They were very quick."
"Go with this company.""Their flexibility to get me in, they were flexible with my time."
"I would use them again if I could have Todd. He did a good job, and he was very nice. I felt that he was very professional and did his job right. I had the film application before, so he had to take the old film off and put the new one on. The old one had been on for 20 years. It was a difficult job.""Their professionalism, they told me what they were going to do, and they delivered. Everything was on time. The clean-up was extremely neat."
"It's great, because it keeps my house cooler, it saves electricity, and it keeps my furniture safe from fading.""It keeps my furniture from fading."
"Their work helps with saving money on heating.""It was very difficult to find someone who actually does this work. There was only one company in the area."
"I should have done it a long time ago.""It has climate control, and I am not sitting there worried that my furniture is fading."


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Obituary & Guest Book Preview for Dino Joseph DalMolin
Dino Joseph DalMolin Obituary
First 25 of 301 words
: Dino J. DalMolin 1967 - 2011 SPRINGFIELD - Dino Joseph DalMolin, 44, of Springfie-ld, passed away peac-efully on Friday March 18th at Mercy Medical Center....
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Dino DalMolin Guest Book | View 2 of 29 Entries:
"To the Dalmolin family: I was saddened to hear the loss of your son Dino. My thoughts and prayers are with all of you. We had graduated from HCC & Disney together. Hold true to the fond memories and..." -
"My deepest sympathy to your family. I went to Holy Name and Cathedral with Dino. I have great memories of Dino walking me home from school at Holy Name. What a wonderful person and friend. He will..." -
Marie Brown-Serrazina
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hand towel with woven stripes
Guide price: £11
Last updated on 20th Aug 2009
Tags: esprit
hand towel with woven stripes
-for the highest standards: fleecy-soft, high quality terry hand towel -with wide, tasteful woven stripes and embroidered logo at one end -absorbent and comfortable -with timeless, modern look -available in various sizes
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What bride isn't a fan of gold glitter? So elegant and timeless, it's the perfect color scheme for complementing your Indian wedding decorations or cooling off guests a jewel tone bridal shower. Place these beautiful gold hand fans on guest tables to make a sparkling statement. You can even personalize them with your names and event details on your choice of a teal or ruby paper applique! Features and facts:
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WHIRLPOOL SYSTEMS ARE A BESPOKE ITEM MADE TO YOUR SPECIFIC REQUIREMENTS – DELIVERY LEAD TIME CAN VARY UP TO 3 WEEKS ACCORDING TO DEMAND ( Please contact our sales team for current delivery dates before placing your order lead times)


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Distances are calculated in a straight line and may not reflect actual travel distance.
Let us help calculate the repayments on this property.Use our mortgage calculator
A rarely available individual and spacious home situated in a village location that offers light and open plan accommodation over two floors. The property has been enlarged and modernized by the current owners to encompass over 2000sq ft of flexible accommodation which takes advantage of the secluded, south facing back garden. The large kitchen & breakfast room gives access through to a lovely dining hall and garden/living room both of which feature vaulted ceilings with easy access to the garden. The second living room can be used as a family room/bedroom with a shower room easily accessed. Both the master bedroom on the ground floor and the second bedroom on the first floor benefit from ensuite facilities, walk in wardrobe areas and views over the garden. A further spacious ground floor bedroom can be accessed from the hallway.
Kings Sutton is located south east of Banbury off the A4260. This is one of the larger villages within the area and facilities include a local shop, village post office, two public houses (one of which was winner of the best gastro pub by the Oxfordshire Restaurant Awards in 2014) and a tennis club. The village has its own main line railway station where London Marylebone and Birmingham can be accessed in around an hour. By road King Sutton is located between junction 10 of the M40, for those wishing to go south, and junction 11 for those wishing to travel north and the motorway can be easily reached in 15 minutes. Primary schooling is available within the village (Ofsted rating"good"), whilst secondary schooling is at the Chenderit School in Middleton Cheney or Bloxham School, in Bloxham.
A large decking area gives access to the main garden which is predominately lawned with well stocked and established perennial flower and shrub borders surrounding. The private garden extends to approximately 120ft, it is enclosed by fencing and well established hedge and trees. Within the decking area there is a quality summerhouse which incorporates a hot tub which is included within the sale. To the front of the property there is gravelled driveway and parking for a number of vehicles with access to the garage.
Additional Information
Double glazing throughout, Gas fired heating, fitted kitchen with belfast sink, fitted oven, grill, dishwasher and hob.
3/4 Bedrooms | Kitchen & Breakfast Room | Dining Hall | Garden Room/Living Room | Second Living Room | Utility Room | Ensuite & Dressing Area To Master & Second Bedroom | 120ft Rear
Garden With Hot Tub | Driveway Parking | No Onward Chain
Contact branch for relevant Energy Performance Certificate


text: No need to choose between style and cosiness with this full-zip curly fleece jacket with cut and sewn panels. Its kangaroo pockets and chest pocket with zip closure provide functionality while Napapijri personalisations and a jersey lining bring a trendy touch to this item inspired by the adventurous polar explorer Sebastian Copeland. Full-zip curly fleece jacket with cut and sewn panels Kangaroo pockets. Napapijri personalisation on the chest. Chest pocket with zip closure. Napapijri personalisation on the chest pocket and upper sleeves. Jersey lining. 90% polyester, 10% acrylic. Color: gray


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Explainer Video
This project received 50 bids from talented freelancers with an average bid price of $571 USD.Get free quotes for a project like this
Project Budget$250 - $750 USD
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Next time wing it-- tell her you ran out of room on the ground, so you are starting a garden on the roof!
> Noreen,
> You're not alone there. I have one of those old 1960s aluminum Florida
> Rooms with aluminum roof. Have cleaned the gutter on that only 3 times in
> 15 years. Even my small hands can barely get in to these tight spaces.
> But I noticed maple seedling sentinels up there - actually a friend noticed
> them, embarrassed as all get out - so I got out the ladder yesterday to
> clean them. The gutter was completely clogged with the nicest compost. I
> dug out what I could by hand, but that still left quite a bit. Fortuantely
> it hadn't rained in several days so it was all rather dry, so I used the
> leaf blower to blow out the rest. Done for a few more years!
> Kitty
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J-a-g-e-r-m ... Ah, Screw It
Any douchebag with nothing better to do can yell out correct answers during classic Scripps Spelling Bee reruns of yore (praise be to ESPN for covering all such nonsporty competitions). It takes a real topnotch wordsmith to step up to the mike, give a decisive throat-clear, and w-i-n without even having to ask for a word to be repeated or used in a sentence. You probably couldnt perform under that kind of pressure or could you? What if the tension were ratcheted up by the kind of peer pressure that only a drinking game can provide? Imagine the high jinks if those middle-schoolers on your telly had just slugged back a shot of booze!
If you think you could not only (a) take one of those baby geniuses out with your mastery of the English language, but also (b) drink their sorry asses under the table, we invite you to put up or shut up at the monthly Drunken Spelling Bee at Purdy Lounge. For every word spelled correctly, you get a shot of Jägermeister. The winner receives a $50 bar tab and bragging rights with anyone in earshot. The shenanigans take place every first Sunday of the month and begin around 10:30 p.m.
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Doctor Jewels Jade sharing dick in hospital with Mackenzie Lohan
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Channel: Brazzers Network
Pornstars: Jewels Jade Mackenzie Lohan


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This classic design was inspired by the cowboy legends of the silver screen. It features 9 snap closures on the front, 6 snaps on the cuffs, distinctive smiley pockets and attractive piping. Scully recommends dry cleaning for all their Western shirts because of the delicate nature of the materials used and the intricate sewing patterns. Rayon and polyester blend.
Scully Tom Horn Shirt Long Sleeve Cotton Black 2XL (52")
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Part of the Grosseto range by Da Vinci, this elegant champagne flute is hand-cut and finished from 24% lead crystal. Made in Italy.
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Whirlpool NEO IC305 PRM 3S 292 L Double Door Refrigerator Wine Orchid
Warranty Period:
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No. of Doors:
2 Door
Energy Rating:
3 Star
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Whirlpool NEO IC305 PRM 3S 292 L Double Door Refrigerator Wine Orchid
Product Details
Warranty Period
1 Year Manufacturer Warranty
Items in the box
Main Unit, User Manual, Warranty Card
Capacity (Litres)
292 Litres
Wine Orchid
Shelf Material
Toughened Glass
Door Type
Double Door
No. of Doors
2 Door
Dimensions (W x D x H)
560 x 662 x 1588 mm
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Energy Rating
3 Star
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Door Lock Feature
Refrigeration Features
Ice Tray
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Frost Free
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Quick Chill Bottle Zone
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3 Shelves
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Social Wine Discovery
Average rating: 3.5 /5
Added by Sue1973 on October 21, 2010
+ new year or type / Share Wine
thirstforwine has reviewed the Gemischter Satz Nussberg Classic 2009 /5
Glad we chose this wine at the EWBC in Vienna in October. It is something a little different from the usual. It has a very pleasant, easy drinking tropical fruit style that still doesn't stray too far from the kind of elegant, complex, slightly spicy style of white wine that one associates with the single varietal wines of Austria such as Gruner Veltliner. The ripe fruit finishes brightly with a lovely mineral freshness. A field blend (Gemischter Satz) offers something distinctive in this variety-obsessed wine market, and to achieve this sort of quality for this price, from a vineyard within the city-limits of a European capital, is something truly unique and definitely worth exploring.
bjwdad What a wonderful discovery! I'm guessing EWBC is "European Wine Bloggers Conference," not "Ewoks With Big Cars." ;)2252 days ago
julia7ich has reviewed the Gemischter Satz Nussberg Classic 2009 /100
Pale green yellow. Discreet melon, lime and pear on the nose. Light, crisp and softly aromatic. Reminds me of a pleasant, breezy spring day. Light-footed and playful fruit and floral components on the finish.
andre has reviewed the Gemischter Satz Nussberg Classic 2009 /20
Slightly tropical nose. Minerality. Acidity is a little lower that the other wines on this tasting but is still enjoyable. Short but nice finish.
cid has reviewed the Gemischter Satz Nussberg Classic 2009 /20
nadali has reviewed the Gemischter Satz Nussberg Classic 2009 /100
Easy wine, I imagine it with some simple food to enjoy with friends.
|Gemischter Satz Nussberg RESERVE 2007white
|Weingut Rotes Haus Grüner Veltliner 2009white
|Gemischter Satz Beerenauslese 2008sweet
|Weingut Mayer am Pfarrplatz & Rotes Haus Wiener Gemischter Satz 2009white
|Wienger Gemischter Satz Nussberg 2009white
|Oct 23, 2010
|EWBC 2010 Closing & Dinner (Sponsored by Austrian Wine)
|Oct 22, 2010
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|Oct 22, 2010
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|Jun 21, 2010
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"Some things you have to do yourself."
As the days wore and the days turned into a week, Sandy seemed to be improving. The doctor was again excited about his recovery and even though he was still in a coma he would on occasion respond to their simple requests, like squeezing her hand, or a small smile when someone said something funny.
He had heard them. He heard all of them, their soft goodbyes, even though they were doing what Kirsten claimed to be a coping mechanism, "Denial is a very effective coping mechanism." He wanted to reach out and touch her face softly and say, "Honey, Da Nile is a river in Egypt," but his brain wasn't functioning properly and someone had placed two-ton weights on his eyelids. He wanted to sob when he heard Seth's innocent plea, and Ryan's belief in him shook him to the core. His wife's was just plain heartbreaking. He couldn't take this, but his body was still hurting so much. He wanted a steady morphine drip. Truthfully however, he would be able to handle everything if he could just wake up and see everyone.
When she went home from the hospital that night Ryan was sitting on the couch with a book in his lap halfway studying and halfway watching Seth play his game console. The boys greeted her with hello and told her that there was Chinese in the fridge. She sat down close to Ryan and watched Seth yell excitedly as he beat a level. She smiled and reached down and ruffled his hair.
"Yeah Ryan?"
"You look like shit. You should get some sleep."
Seth laughed out loud before he looked at her sheepishly.
To both of their surprise she laughed with them and told them she would take him up on his offer and walked up the steps to go into their bedroom, but Ryan stopped her.
"I just want to make sure you're okay," he whispered softly his eyes full of concern and love for her.
She smiled at him. Always the savior, always trying to make sure everyone was fine. He had really stepped up to the plate since the accident, taking over her husbands place as the supporter. She knew how he felt about Sandy. When he wasn't paying attention she watched how he looked at her husband, even at her. His expressions showed nothing but awe, admiration, gratitude and appreciation it decorated his face when either of them walked into the room. This was hard on him too, and he was just checking to make sure that she wasn't going to break down, whether he would admit it to himself or not, he relied on them on their guidance and love. And right now the invincible twosome lost a valuable member.
"I'm fine, are you okay?"
He nodded his head.
"Okay," she whispered and she reached up and ruffled his hair. "Goodnight sweetie."
"Goodnight," he called watching her go.
When Ryan returned he and Seth stayed up playing games talking softly to each other.
"She seems okay…"
"Just keep an eye on her Seth."
Seth looked at Ryan like he was foolish but shrugged his shoulders and they continued their friendly banter back and forth.
Later that night when they had finished eating and he thought his mother was out of earshot, Seth took a turn.
"What if he dies Ryan? What are we going to do?
Ryan stopped tying the plastic bag, obviously taken off guard, and Kirsten leaned against the doorframe, out of sight, listening.
"I don't know… We'll get through it together. That's the only part I'm sure of."
She smiled at how thoughtful he was.
"What about if he comes home, what if he's like a different person?"
"Of course he's going to be different."
"It's been so weird without him. You know? I wish he hadn't played hero."
"Yeah Seth. You know cause he really wanted to take that bullet. He probably held up a neon sign, saying Shoot Me Here! Christ Seth, he was protecting your mom. I would have done the same."
"You always play hero," Seth muttered.
"I do what I think is right to protect people…cause no one ever did it for me," he looked at him, anger flushing his normally quiet features. Sandy was the one person who made it okay for him for once in his life. He was the one person who didn't raise his hand to him, or yell obscenities. He stood behind him in most of his decisions, bad or good, and guided him. He stood behind him proudly when he couldn't tie his own tie and was embarrassed to ask for help. He didn't hesitate reaching around straightening up his collar and stood there for a few moments just smiling at him.
Sandy took a chance with him and Ryan would be there for him. In truth, if Sandy said jump, Ryan would ask how high.
"You know something Seth. You really don't know how good you got it. How good you've had it your whole life. Your mom never laid a hand on you; she barely has ever raised her voice your way. Your dad never raised his hand to you; both of them have shown you nothing but affection. It's nice to come home to a family that you don't have to defend yourself against, especially when at school maybe that's all I did there too. So stop being such a little bitch. Grow up, and face what comes your way with him. Because I will."
Seth looked at him wide-eyed. He didn't really realize in his slight babblings that he was still thinking of himself and not his father.
"When did you become so expertise in family values?"
"Oh Jesus Christ Seth. I'm done talking to you about this," he sighed.
"You're right Ryan. Sorry."
"Don't apologize to me. Think a little Seth, maybe about others for once. He's your dad. Even if he and Kirsten are fighting there isn't anything they won't do for you, or me."
Ryan walked past him and gave him a look, dragging the garbage outside. Kirsten quietly walked away from the scene, watching as Seth stalked off angrily. She suspected that his anger was from being so scared.
Walking into her empty bedroom, sometime during the days that had blurred by Rosa had cleaned up Sandy's shorts, and clothes that had been tossed about. She frowned slightly as she changed her clothes for she was facing another endless night alone. Every time she found herself sound asleep she would reach for him and the emptiness would wake her up. It was if her mind didn't want to believe that he was away. 'Seventeen years of reaching for someone and succeeding, well I guess you just don't forget it overnight,' her conscious reminded her. Just like it had reminded her she was lucky, still lucky because he was still alive. She pulled back the covers and climbed in. She could still smell him on the sheets and his pillow. She pulled his pillow close to her body and inhaled him. This would have to do for now.
The nurse that had been attending to Sandy, Janna, was humming to herself, during her routine vital check when he awoke in a blind panic. Literally. She rushed to his side, holding down his hands so that he didn't pull out his I.V, or stitches.
"Easy there ma' dear," she whispered. "Focus, Focus, now. Atta' boy, Der you go handsome. Easy now."
Sandy awoke to a bright unfamiliar room. He did what anyone would do. He panicked. His vitals shot up ringing off alarms, when he jerked pain roared up his chest and his arm, where the I.V was.
"Hey there hon-ay, It's a'ight, we gon getcha fixed up a jiffy," her foreign accent rang through his ears.
Oh God. He was dead. This was an angel or something from another world. No one spoke like that around here.
For a second he couldn't breath as fear paralyzed him. His eyes danced nervously about the room as she took his vitals and calmed him. Where? Why? Where was his family? His chest was on fire; it almost hurt to breath again.
"Now, now, you okay? Look at me here there ya go handsome. Lookie here," she said making him stare at her chocolate brown eyes. "You're in the hospital sweetie, okay, you're okay."
The hospital. The images of his wife crying ran through his brain. He remembered, and it terrified him even more. He heard Janna's words and he relaxed, just enough so she took advantage of it.
"Okay sugar, I'm gonna run and get the doctor, mmm-kay, just relax. You're okay. My names Janna, sweetie, okay? I'll be right back."
He reached out and placed a shaky hand on her arm. "Where's my wife?"
"Oh sugar, she's at home honey. Its three am, now you hang tight, be back in a flip."
He sighed. Okay. Okayokayokay. No. Not it wasn't okay, he wanted to cry right now.
Alex Rudley breezed into his hospital room, excited. "Mr. Cohen, you gave us all a scare. How do you feel, other than disoriented? Lets go over some things," he stated as he started listening to his heartbeat and his lungs. He asked if anything was tender when he pushed on it. Sandy literally felt fine, to the sense. He groaned softly when the doctor placed his hands on his chest. He didn't want this guy, or this nurse, who was keen on him and kept calling him sugar, honey, and any other candy name she could think of. He just wanted his wife, his boys. He wanted to lay on the couch with her, and watch Seth play, play station while babbling to Ryan. He wanted to reach out affectionately and ruffle Ryan's hair, while Kirsten smiled. He was scared. He just wanted familiarity.
"Doc, Please, can you call my wife?" His blue-green eyes pleaded with him. Begged. PLEADED.
The doctor smiled at him, breaking a hospital policy, but he reached for the phone dialed the number for him and handed the phone to Sandy.
The phone rang at three-thirty in the morning. Her brain thought the worst.
He's dead.
She felt panic-stricken when she reached for the handset, took a deep breath and prepared herself for the worst.
"Hello?" She asked weakly.
"Hey honey, if it's not to much to ask, do you think you could come see me," his tired voice spoke softly on the phone. "Please?"
She smiled through her tears, "In a heartbeat."
Kirsten woke both boys telling them the news, and they both jumped to their feet and got dressed quickly. However the boys weren't going to stay long. They needed to get to school both had tests in at least three classes. But they needed to see Sandy. They drove separately, the boys taking the BMW.
Walking in the room, they looked at him apprehensively. He looked like he was sleeping, but when he heard the door open he opened his eyes in disarray. He smiled weakly at them, "Hey guys!"
Ryan broke into a huge grin, as did Seth. Kirsten's eyes brimmed with tears.
Ryan was the first to find his voice, "Hey yourself, stranger."
Sandy broke into a grin, and they crossed over to the bed. Seth was the first to lean down and hug his father. "Hey dad," he whispered softly. Sandy's arms reached up and gently held the boy close for a moment.
He felt home. Ryan was next and did so with a huge grin. He pulled back and it was Kirsten's turn. She managed a small smile and her bottom lip trembled. He smiled up at her knowingly, she crossed the distance, placing a small kiss on his forehead before leaning down and kissing his lips.
"I missed you guys," he said as he watched Seth cross over to the other side and sit down on his bed. Kirsten and Ryan followed suit on the side that they were on.
"Dad, we missed you too, Mom was trying the corny jokes and Ryan was semi upbeat and happy, not brooding. He danced around in black socks for entertainment!" Seth babbled.
The smile that was evident on his face mirrored everyone's in the room. "Ryan, I hope they weren't mine," he whispered weakly.
"Of course, I'm not going to ruin my own socks!"
Kirsten smiled at Ryan and ruffled his hair. Seth grinned. Sandy smiled and then yawned. He was so tired. Seth and Ryan looked at each other, and then the clock, it was a quarter to four. "Dad, sorry to cut this short, but Ryan and I are going to head out, you're tired and you probably want some 'mom' time, so to speak.
He smiled at his boys toexhausted to argue, "Kay, I love you guys.
Surprisingly both of them yelled back, "Love you too."
Kirsten walked them out of the hospital, "Be careful driving home."
"We will." And like that, they were gone.
She thought for a second he was sleeping when she walked back into his room. His eyes had been closed and his dark hair was every direction other than straight. He must have sensed her because he smiled and opened his eyes, looking in her direction. His face was a pale, eyes showing exhaustion; he was struggling to stay up for her. He patted the bed beside him. Her eyes welled up with tears and she sat on the bed near him. She looked at him apprehensively but he calmed her fears, reached over and lovingly ran the back of his hand against her cheek. She leaned into his touch placing her hand over his, and he pulled her closer and kissed her lips softly.
"Beautiful," he said softly looking at her, "Such a sight for sore eyes."
She could only imagine what a sight she truly was.
"I was scared baby," he whispered so softly, "I woke up and …" he trailed off looking at her like a little boy. Sandy looked lost.
"I love you," she whispered, reassuring him the only way she knew.
He closed his eyes and bit his bottom lip "I love you too, so much." She kissed him again, leaning her forehead against his.
Closer. The need to be closer was adamant.
He moved his weary body over a little bit, groaning as he shifted his weight but he tugged at her hand, begging her to join him.
She looked wide-eyed at him and was hesitant. "Kirsten, I know you haven't slept. Come on," he said tenderly, knowing her sleeping habits mirrored his when she wasn't there.
Truthfully he was shaken and he just wanted the safety of her beside him. Calming him.
She looked at him the fatigue evident on his tired face and then eased herself against him, his arm wrapping around her, holding her closely to him. His blue-green eyes closed and he sighed quietly.
She was nervous against him and he grasped her hand, guiding it over his wound to his heart. She could feel the heat radiating from it as her hand passed over it. "You're not gonna hurt me, relax baby."
"I was scared, Sandy. I was so scared," she confessed to him.
"I know honey. I heard everything. Even when I couldn't respond, I still heard you and I'm sorry. I'm sorry I couldn't protect you from that." He kissed her forehead and she closed her eyes.
"Its okay. You're okay. That's all that matters to me. My boys are safe," she whispered.
"I missed you," his deep voice rumbled softly.
She can only nod as a tear slips down her cheek. "Oh God Sandy, you have no idea."
He smiled weakly, closing his eyes, taking pleasure in her closeness. "I love you Kirsten. I love you and I can't leave you, not with Jimmy Cooper out there."
She chuckled, "Only you would be thinking of Jimmy Cooper right now."
"Actually the only thing I'm thinking of would probably kill me cause I don't have the strength to keep up…"
She nudged him tenderly with a smile.
"Oh honey, don't think I don't know how your mind works, you've been trying to jump my bones since I got in this place," he protested faintly.
He pressed a kiss into her hair, resting there, inhaling her scent. "Beautiful, you're so beautiful."
She closed her eyes. She too, was home.
Six days later Sandy was released from the hospital with the follow up the subsequent week.
For a month and four days Kirsten had laid in their bed alone. She hadn't slept much. Tonight at least she could look at him while he slept, which he was surely about to do. She could reach out for him in her sleep. She could hold his hand, listen to him breath. She could rest in his arms; savor the fact that he was alive, and safe against her. He was leaning against the window of the Rover his eyes were closed, but a small smile played upon his lips.
Walking in the mansion he was greeted by his two boys who gave him gentle hugs, trying not to hurt him. They were fierce but gentle hug that made sure they knew how much he was actually missed. Jimmy, Julie, Caleb, Marissa and Summer had stopped by. Everyone was glad to see him, even Caleb was civil and joked around with him instead of sneering. He leaned on Kirsten, an arm around her waist supporting his weight some. He looked at her and she was smiling as she talked to her dad. He leaned over and placed a tender kiss on her forehead and disengaged from her. She looked up at him and watched as he retreated to the kitchen where he was surprised to find Ryan.
He eyed him, looking for a sign but Sandy just lumbered in and plopped in a chair.
"Exhausted huh?" Ryan asked quietly.
Sandy looked over wearily, using 'the look', and a yawn to hopefully convey just how he felt.
"You want me to help you up the stairs and to bed?" he asked almost hopefully.
"Sure kid, that would be great. I just can't stand up anymore, I'm dead on my feet."
Ryan grabbed hold of one arm as they slowly went up the stairs. He led Sandy over to the bed and let go, watching as he slowly eased himself on the mattress, sighing in relief.
"Thanks son," he smiled faintly. "I feel horrible for not being as strong as I normally am."
Ryan just nodded. He didn't know whether to go or to stay. He would have liked to stay and talk, or just watch TV.
He shoved his hands in his pockets, "Do you uh, do you want me to leave?"
"I'd like it if you could keep me company for a while. Kirsten's going to be pissed I left her and didn't say anything. You may have to protect me from her," he closed his eyes.
Ryan eased himself on the bed near Sandy, crossing his legs sitting Indian style. "Hey you want me to go get anything, something to drink or something?"
"Water would be good," he said softly.
Ryan took off on his quest to get a bottle of water for himself and Sandy. On his way downstairs he ran into Seth who asked where he had been.
"I helped Sandy upstairs, he's tired, and so we're watching TV and hanging out." Ryan was still leery of Seth since he had somewhat flipped out on him but if he was willing to let bygones be bygones than so was he.
"Oh, hey good idea let me grab Summer. We'll be up."
Ryan looked at Seth, shrugged and walked back up the stairs. He handed Sandy the bottle of water and got comfortable on the bed. A few moments later both Seth and Summer joined them, making themselves comfortable around him. Sandy raised an eyebrow, "You guys don't have to be up here just cause of me."
"Ew Mr. Cohen, we want to be here. We all missed you, you know? Summer bluntly pointed out.
He smiled. Leave it to Summer, she always said what was on her mind. "Mmm-Kay," he mumbled leaning back against headboard, watching the movie they had picked out. Both Ryan and Seth were leaning on Sandy and he welcomed their closeness. He shifted and put his arms around both his boys they had settled against him contentedly. Ryan was actually sound asleep. Both Summer and Seth had long ago fallen asleep as well. Sandy was struggling to stay awake, it was then when Kirsten entered the room and gazed upon the site before her.
"Sandy, God, I was . . .." she stopped when she saw the boys sleeping and Summer. He looked up at her a bashful grin played upon his tired face.
"Hey," he whispered.
"Hi…they're all sleeping," her voice was awed.
He looked over the kids and nodded.
She eased herself on the bed, the movement waking Summer even though she had tried to be careful, and she groggily sat up.
"Hey sweetie," Kirsten said softly, her hand reaching out, sweeping a stray strand of hair away from her face.
"Do I have to go?"
"No baby, hold on a second," she whispered as she leaned over and got herself comfortable, placing an arm around the girl. To her slight surprise Summer curled up against Kirsten like she was her own daughter. She smiled and ran her hand lovingly through her hair and was rewarded with a soft, "Thank you, Mrs. Cohen."
"No problem sweetie," she pressed soft kiss onto her forehead and she looked over to see Sandy smiling at her. He mouthed 'I love you.' Through the disarray of children, his hand found hers.
She mouthed it back to him.
At some point in the wee early hours of the AM Ryan awoke. He was slightly disoriented until he realized they had all fallen asleep in the safe arms of Sandy. Summer was curled up against Kirsten. Now this would be the perfect picture. He managed to disentangle himself from Sandy's grasp, and woke Seth and Summer without waking either parent. He was proud of himself. They crept out of their rooms, Seth and Summer going into his and Ryan crashed in the guestroom, to tired to walk out to the pool house.
Sandy shifted in his sleep facing away from his wife, as his conscious mind told his body that would be the safest position without pain. She however felt the lack of warmth from the sudden loss of bodies on the bed and reached out for Sandy. She pulled her body close to his wrapping an arm over his warm body and his hand covered hers. Finally her wish had been granted, she could reach out for him and actually find his warm body, not just empty cold space. She smiled into his shoulder blade, he was home, and everything was going to be fine.
"I love you Sanford Cohen, but if you ever pull a stunt like that again, I'll shoot you myself."
She felt him chuckle and whisper, "I love you too, pumpkin muffin."
She fell asleep with a smile on her face.
He was home and safe, her boys were safe, and finally everything was going to be just fine.
I hoped you all enjoyed this. It was truly only meant to be a little drabble and it turned out more than that.
If you liked this, check out Rhyme or Reason, apparently people don't think it's too shabby either :o)
Thanks for the reviews!


text:
Great photo, Brock. I hope we all get to enjoy your new camera.
My season is over and done. Supposed to be 98f today, with winds
upwards of 30mph. Hot, drying winds. We need rain, so this year is
back to normal after the wet summer last year.
I look forward to seeing the ABs that bloom in your locale. I think
ABs are being grown successfully in a wider geographical range than a
lot of people realize. They really have a varied genetic background,
so I would expect some to do well and others not - same as they do
here. And the same as the other iris classes do here. It's just a
matter of locating which ones manage my conditions and what I can do to
help them manage. I expect my end of it falls short most of the time.
Donald Eaves
Texas Zone 7b, USA


text:
Curtis Arledge*
Cuong Do*
Barry R. Feirstein
Nanci Fredkin
Philip H. Geier, Jr*
Matthew Higgins*
Dee Hilfiger
Tommy Hilfiger
Adrian M. Jones*
Tim Jones
Mel Karmazin*
Brian Kelly*
Billy Mann
Gary Mayerson
Kevin Murray*
Valerie Paradiz, PhD
Herbert Pardes, M.D.
Jamie T. Richardson
Andrew Robertson
Chuck Saftler
Stuart Savitz*
Dan Schulman
Stephen Shore, Ed.D.
Laura Slatkin*
John B. Wilson
Steven P. Stanbrook
Joseph T. Coyle, M.D.
Bob Wright*
*Executive Committee Members
**Staff Officers
Curtis Arledge
Vice Chairman and Chief Executive Officer, BNY Mellon Asset Management
Curtis Arledge is Vice Chairman of BNY Mellon and Chief Executive Officer of BNY Mellon Asset Management. Additionally, Curtis is responsible for BNY Mellon Wealth Management, and is a member of BNY Mellon's Executive Committee, which is the senior-most governing body of the corporation. Prior to joining BNY Mellon in November 2010, Curtis was the chief investment officer for fundamental fixed income portfolios at BlackRock, Inc. He joined BlackRock from Wachovia Corporation, where he was the global head of the fixed income division within the bank's corporate and investment banking group. He spent 12 years of his career at Wachovia, and had oversight for various business lines in the U.S., Europe and Asia, including leveraged finance, investment grade, global rates, structured products, corporate loan and commercial real estate portfolios, and financial institutions investment banking. He and his wife, Diane, have a son on the autism spectrum.
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Executive Vice President, Global Strategy Group, Samsung
Cuong Do is Executive Vice President, Global Strategy Group for Samsung. Cuong is responsible for helping set the strategic direction and improve the performance of Samsung's many businesses. Prior to Samsung, he was the Chief Strategy Officer for Merck, Tyco Electronics, and Lenovo. He was also a former senior partner at McKinsey & Company, where he spent 17 years and helped build the Firm's healthcare, high tech and corporate finance practices.
Between his roles at Merck and Samsung, he "retired" for a year to devote most of his time to addressing the challenges of autism. Between 500,000 and 1 million teenagers with ASD will transition to adulthood in the next decade. However, there currently no tools, approaches, processes to help parents of these individuals understand what their children are able to do and are interested in – without which one cannot help put in place appropriate post-secondary education options, jobs and support for housing and transportation. Cuong worked with his wife to launch Identifor (www.identifor.com) to develop new approaches to help these individuals identify abilities, skills and interests so that meaningful post-secondary educational and vocational plans can be pursued.
He holds a Bachelor of Arts degree from Dartmouth College, New Hampshire, U.S. and a Master of Business Administration from the Tuck School of Business at Dartmouth, New Hampshire, U.S. He serves on Autism Speaks' Executive, Family Services, and Science Committees. He founded Profectum Foundation as a non-profit working to train clinicians and parents on working with autistic children. He currently or previously served on the boards of Celebrate the Children (school for children with special needs), Caring for Cambodia (non-profit working to establish the model schools for Cambodia); the National Youth Science Foundation, the Tuck MBA Advisory Board, and WuXi AppTec (leading pharmaceutical R&D outsourcing company). He was co-founder and Chairman of Callidus Biopharma (a biotech company working in rare diseases) and Lysodel Therapeutics (company developing an innovative pharmaceutical product for obesity).
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Barry R. Feirstein is the retired founder of Feirstein Capital Management, a private investment management firm.
He is a graduate of Brooklyn College and the Harvard Business School. Barry's current activities are focused on non-profits and the arts.
He has served two terms as the Chairman of the Brooklyn College Foundation. While serving at the foundation he founded the Barry R. Feirstein Graduate School of Cinema. This state of the art school is located at Steiner Studios in Brooklyn. It is to be one of the only film schools to be located in a working studio.
Barry is the chairman of the Anderson Foundation for Autism, he is on the board of the Film Society of Lincoln Center, and he is a past president of the Friars Foundation.
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Nanci Fredkin
Nanci Fredkin is a former board member of Cure Autism Now, where she gave nearly $70,000 from 1999-2007. Nanci created Facing of Autism as a fundraiser in 1998. She redesigned and re-launched this highly successful fundraising event in March 2012 which took place in San Francisco, bringing in nearly $500,000 for Autism Speaks. Her personal connections and dedication in developing and executing the event was invaluable and she also gave $20,000 in donations to the event. Nanci is also a member of the Board of Directors of Telecare Corporation. The organization encompasses a family legacy that she is very proud to continue. Nanci worked in banking and was an account executive for the Estee Lauder Corporation. She has used her business experiences and brought her insight and judgment to various non-profit organizations as well as to Telecare. Nanci has a passion for and has made a commitment to children and healthcare issues. She sits on the Foundation Board of the University of California San Francisco and Theater Works Silicon Valley Board.
Nanci resides in the Bay Area of California with her husband Gary and three children.
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Chairman, The Geier Group LLC
Philip H. Geier, Jr., an advertising professional, became Chairman and Chief Executive Officer of the Interpublic Group of Companies, Inc., in 1980. He retired from this position at the end of December 2000.
In February 2001, Mr. Geier formed The Geier Group to provide consulting/advisory services in the marketing, communications and venture capital areas.
Additionally, Mr. Geier is a Senior Advisor for Lazard Frères & Co. LLC and serves on the Board of Directors for the following companies: AEA Investors, Inc., Fiduciary Trust International, and Mettler-Toledo International, Inc. Mr. Geier's philanthropic relationships as Director or Trustee include: Autism Speaks, Columbia Business School, Memorial Sloan-Kettering Cancer Center, Save the Children Federation, Inc., The Whitney Museum of American Art, and International Tennis Hall of Fame.
Mr. Geier holds a B.A. in Economics from Colgate University (1957) and an M.B.A. in Marketing and Finance from Columbia University (1958).
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President and CEO of RSE Ventures
Matt Higgins is the President and CEO of RSE Ventures, a firm developed to foster innovation within sports, entertainment and technology. Matt co-founded RSE in 2012 with Miami Dolphins owner and Related Companies founder Stephen M. Ross. In just a year's time, RSE has experienced explosive growth, breaking down boundaries across a space that is notoriously slow to innovate. RSE has made investments in many emerging technologies and launched numerous startups: Derris & Company, a communications and brand strategy agency boasting over 30 clients in entertainment, media, technology, finance and sports; Insignia SE, a sports marketing firm representing top sports properties and leading consumer brands; and Relevent Sports, an international soccer agency that launched the International Champions Cup, featuring the biggest teams in the world competing across the United States. Early stage investments include cutting edge companies such as Preplay Sports, Thuzio and Poptip. Higgins also serves as a Vice Chairman of the Miami Dolphins.
Before co-founding RSE, Mr. Higgins served as EVP of Business Operations of the New York Jets, where he transformed the team's business operations into one of the most innovative in sports. During his tenure, the Jets created a permanent home for the first time in franchise history by partnering with the Giants to build MetLife Stadium. Higgins also helped spearhead the effort to create the most state of the art practice facility in the NFL, building a headquarters for the Jets on 20 acres in Florham Park, New Jersey. His passion for innovation also led Higgins to elevate the Jets' national profile through unorthodox brand extensions, including a partnership with Jet Blue to create a dedicated Jets' jet flying routes around the country. By making team operations transparent and increasing access to its players, Higgins used social media to give fans and press unprecedented access to the team.
Prior to his career in sports, Higgins helped lead the recovery effort in Lower Manhattan following 9/11. As COO of the Lower Manhattan Development Corporation, the agency charged with rebuilding the World Trade Center site, Higgins helped implement programs and grants that revitalized Lower Manhattan in the aftermath of the attacks. In addition, he helped oversee the 9/11 Memorial design competition, which became the largest design competition in history with more than 5,000 entries from 63 countries. Prior to the LMDC, Higgins served as Press Secretary under Mayor Rudolph W. Giuliani, managing the City's global media response to 9/11. In 2011, Higgins was recognized in Sports Business Journal's 40 Under 40 as one of the most outstanding executives in sports. Four years earlier, Higgins was honored as one of the top 40 executives under 40 in New York by Crain's New York.
Higgins holds a Bachelor's Degree in Political Science from Queens College, and a Juris Doctorate from Fordham Law. Higgins is a proud testicular cancer survivor who has taken up marathon running as a way to maintain a healthy lifestyle. He lives in New Jersey with his daughter Collette and son Matthew. He is the father of a child with autism.
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For 25 years, Tommy Hilfiger has brought classic, American, cool apparel to consumers around the world. His designs give time-honored classics a fresh look, and his discerning taste has provided the foundation for the growth of a global brand.
Under Hilfiger's guidance, vision and leadership as principal designer, the Tommy Hilfiger Group has become one of very few globally-recognized designer brands offering a wide range of American-inspired apparel and accessories.
Born the second of nine children in Elmira, New York, Hilfiger's career in fashion began as a high school student in 1969, when he opened a small chain of stores called People's Place with just $150. His goal was to bring "cool big city styles" from New York to his friends in their small town in upstate New York. Hilfiger soon began designing for the boutiques he had always admired, and in 1979 he moved to New York City to pursue a career as a full-time fashion designer. There, he caught the eye of Mohan Murjani, a businessman who was looking to launch a line of men's clothing and believed that Hilfiger's entrepreneurial background gave him the unique ability to approach men's fashion in a new way. With Murjani's support, Hilfiger introduced his first signature collection in 1985 by modernizing button-down shirts, chinos, and other time-honored classics with updated fits and details. The relaxed, youthful attitude of his first designs has remained a distinctive hallmark throughout all of Hilfiger's subsequent collections.
As Hilfiger's designs merged with popular culture, he began to extend his company's distinct brand message across a variety of mediums and platforms, including the introduction of Tommy Hilfiger Collection, men's tailored, Hilfiger Denim, men's and women's sportswear, childrenswear, bodywear, footwear, accessories and licensed products such as watches, jewelry, eyewear and fragrance.
Tommy Hilfiger launched The Tommy Hilfiger Corporate Foundation in 1995 to enrich the physical and intellectual well being of youth, with a major emphasis on education and cultural programs. In 2013, all Foundation activities around the world aligned under the global banner of Tommy Cares, to unite the brand's philanthropic commitments, non-profit partnerships and employee engagement. Hilfiger is actively involved in supporting charitable causes including Autism Speaks and the MLK, Jr. National Memorial Project Foundation. He has also served on the board of directors for The Fresh Air Fund, a New York-based group that has been sending underprivileged children to summer camp since 1877. On a global scale, Tommy Cares supports Save the Children, the World Wildlife Fund, War Child, Breast Health International (BHI), and Millennium Promise.
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Co-Head of the Americas, Goldman, Sachs & Co.
Adrian M. Jones is a Managing Director at Goldman Sachs in New York in the company's Principal Investment Area. He joined Goldman Sachs in 1994 as an associate of the Investment Banking Division. He has also served in the company's Communications and Media Department, on mobility assignments in Equity Capital Markets and in the Executive Office of Goldman Sachs International in London. Jones grew up in Ireland and served as a Lieutenant in the Irish Army. In 1987-88, he served in the United Nations Peacekeeping Force in Southern Lebanon. Jones is a 1986 graduate of University College in Galway, and earned his MBA from Harvard in 1994. He is the father of a child with autism.
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Tim Jones
CEO, ZenithOptimedia North America
Leading The ROI Agency in North America, CEO Tim Jones is committed to ensuring that each agency client receives a better return per media dollar invested than any of their competitors. Managing ZO's industry-leading North American media brands, Tim also serves as a member of the ZO worldwide executive committee.
Under Tim's leadership since 2005, ZO has experienced unprecedented growth. Ranked by the Research Company Evaluating the Media Agency Industry (RECMA) as the second largest, fastest-growing agency, ZO has welcomed a world-class roster of new clients including Nestlé, Twentieth Century Fox, Payless Shoes, Ubisoft, Harrah's, Jenny Craig and Reckitt-Benckiser. ZO's new business success and the retention and expansion of existing client partnerships have also garnered RECMA's highest three and six-year agency performance scores.
Helming the charge into digital and diversified offerings Tim has been a leader of evolution. With the acquisition of Moxie Interactive and the strategic alignment of Performics, ZO's interactive billings total more than $550 million and represent one of the industry's largest digital units. The development and growth of econometrics, direct response, Newcast all-platform content and multicultural now offer agency clients a full complement of powerful diversified communication solutions.
Tim's career started in 1978 and has included service at Ogilvy and Mather, Bates and ZO International. Among other awards, in 2007 Tim was named an AdAge Media Maven.
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Mel Karmazin
CEO, SIRIUS Satellite Radio
Mel Karmazin served as CEO and member of the board of directors of SiriusXM from July 2008 until January 2013 when he retired. Prior to that, he served as CEO and member of the board of directors of Sirius Satellite Radio from November 2004 until its merger with XM Satellite Radio.
Previously, he was President and COO of Viacom from May 2000 until June 2004. Karmazin served on the Viacom board of directors and was responsible for overseeing all of Viacom's operations. Prior to that, he served as president, CEO, and member of the board of directors of CBS Corp. from January 1999 to May 2000. Before becoming chief executive officer, he was president and chief operating officer of CBS Corp. from April 1998 to January 1999.
He joined CBS in January 1997 as chairman and CEO of CBS Radio through a merger of Westinghouse/CBS and Infinity Broadcasting. He had served as Infinity's president and CEO from 1981 until Infinity became a wholly owned subsidiary of Viacom in February 2001. He was named chairman and CEO of CBS Station Group in May 1997. Prior to Infinity, Karmazin spent 10 years with Metromedia.
He is involved in numerous philanthropic ventures and has served on a number of boards throughout his career. Currently, he serves as a Trustee at NYU Langone Medical Center, a board member and Executive Committee member of Autism Speaks, and Vice Chairman of the Board of Trustees of The Paley Center for Media. He was inducted into the Broadcasting Hall of Fame, and has received the National Association of Broadcasters National Radio Award and the IRTS Gold Medal Award.
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Brian Kelly
Chairman, Autism Speaks
Principal, Eastern Real Estate, LLC
Brian Kelly was elected Chairman of the Board of Autism Speaks on May 1st of 2015. Kelly has long been an integral part of Autism Speaks as a founding member of the Board of Directors and its Executive Committee. Prior to his election, Kelly served as Chairman of the Audit and Family Services Committees. Kelly is co-founder of Eastern Real Estate LLC, a leading commercial real estate investment, development, and asset management firm. Eastern has orchestrated transactions of more than 25 million square feet of commercial real estate and developed more than 100 projects totaling over 12 million square feet with a value of over $2 billion dollars.
Brian Kelly has had a longstanding and deeply personal commitment to autism and autism related causes. In 2006, Kelly led the development and property acquisition of the Melmark New England school in Andover, Massachusetts. Melmark School services individuals with autism and other disabilities. In 2007, Kelly and his wife Patricia funded the construction of the Koegel Autism Center at the University of California, Santa Barbara, a $2.4 million dollar project that was completed in 2009. The Koegel Autism Center is world renowned for their Pivotal Response Treatment for individuals with Autism. In 2008, Brian Kelly was the recipient of the University of California, Santa Barbara's Gevirtz School's Thomas G. Haring Memorial Award which honors achievement in special education. In 2013, the Kelly's established the Brian & Patricia Kelly Postsecondary Scholarship Fund at Autism Speaks to support vocational and educational opportunities for young adults on the spectrum.
Brian Kelly was raised in New York and spent most of his adult life in Boston, where he met his wife Patricia. In 1994, Kelly was honored as a recipient of the Gilda Radner Courage Award which recognizes a cancer survivor whose courageous public battles have given hope to people with cancer and focuses public attention on the fight against the disease. Brian and Patricia Kelly now reside in Santa Barbara, California with their six children. Their eldest child, Patrick, has autism.
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Music Producer, Songwriter
CEO of Green Bloom, Inc/BMG, a Joint Venture between Mann and KKR/BMG Chrysalis Rights Management
Billy Mann is a Grammy-nominated accomplished hit songwriter, producer, artist, executive and entrepreneur. Mann's active discography includes P!nk, Cher, Sting, John Legend, Take That, Kelly Rowland, Hall & Oates, Martina McBride, Celine Dion, among others, and has written numerous Top 10 hits and achieved sales of over 125 Million albums.
Beginning as an A&M artist in 1994, after two albums, Mann's ambition helped him pivot towards writing, producing and entrepreneurialism. In 2001, he founded Stealth Entertainment, a talent development company with special focus on brand partnerships. EMI acquired Stealth in 2007 Mann was soon-after appointed President of International/Global Artist Management, overseeing EMI's rosters in over 30 countries. In late 2010, Mann was appointed President of Creative-BMG North America before becoming CEO of Green & Bloom/Topline the following year. An aggressive, songwriter-led publisher, in only 3 years Green & Bloom/Topline has offices on both coasts, over 40 songwriters, 3,000 copyrights and chart-topping successes around the globe representing copyrights that vary from David Guetta to Eric Clapton to John Legend and more.
Mann is a national board member of Autism Speaks serving on the Advocacy and Digital Committees, co-founder of the Rema Hort Mann Foundation and was an elected Governor of Songwriters in New York for the National Academy of Arts & Sciences (Grammys). In 2007, Mann helped draft the Autism Policy for the Obama/Biden Presidential campaign (also securing a dedicated "autism" destination on their digital platform) and later had the honor of watching his oldest son, Jasper, receive the first pen in the Oval Office from President Obama after he signed H.R. 2005, the Combatting Autism Reauthorization Act in 2011. In December 2013, The Manns were presented The Champion Award at The Autism Winter Ball at the Met by friend Senator Bob Casey (PA), original sponsor of the ABLE Act. Mann resides in Connecticut and is a proud husband and father of four children.
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Founding Attorney, Mayerson & Associates
Gary Mayerson, a board member since 2005, is a graduate of the Georgetown University Law Center and the S.I. Newhouse School of Public Communication at Syracuse University. In early 2000, Gary founded Mayerson & Associates as the very first civil rights law firm in the nation dedicated to representing individuals with autism and related developmental disorders. To date, Gary's law firm has helped more than 1,000 affected families in more than 30 states. Gary also consults internationally to military and other families living abroad.
Gary and his firm are responsible for more than 60 reported federal court decisions, including the very first autism case to ever reach the U.S. Supreme Court. Many of Gary's federal court decisions are recognized as groundbreaking decisions that are shaping the way that the court system looks at autism. Gary also serves as the Director of the Autism Speaks Federal Legal Appeals Project ("FLAP"), a pro bono initiative at the national level.
Gary speaks regularly at national conferences and major universities and has testified before Congress on the subject of the federal Individuals with Disabilities Education Improvement Act ("IDEIA"). Gary is the author of How To Compromise With Your School District Without Compromising Your Child (DRL Books 2005), as well as the "Autism in the Courtroom" chapter appearing in the Fourth Edition of Dr. Fred R. Volkmar's seminal treatise, Autism and Pervasive Developmental Disorders (Wiley 2014) and the legal considerations chapter appearing in the Auditory Processing Disorders (2nd Edition, 2013).
Gary is married with three children and has a family member with autism.
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Kevin J. Murray
Managing Dir., BNY Mellon Investment Management
Kevin J. Murray is a Managing Director for BNY Mellon Investment Management. Mr. Murray is focused on strategic initiatives in alternative assets and non-traditional investments. The BNY Mellon Investment Management group currently manages over $1.6 trillion in assets for institutional and HNW clients globally. Formerly Mr. Murray was the Managing Director and Head of Business Development for G2 Investment Group/Forbes Private Capital Group. Based in New York, he was responsible for originating and marketing G2-sponsored private equity and hedge funds and third-party investment opportunities through its global institutional and ultra-high net worth network.
Prior to 2011, Mr. Murray was the Director of Marketing at Federal Street Partners, a multi manager fund focused on emerging managers. In 2005 Mr. Murray Co-Founded Rock Ridge Advisors, LLC, a macro hedge fund with an institutional client base. Mr. Murray was a partner and also served as COO, CCO for Rock Ridge Advisors. Prior to forming Rock Ridge, Kevin was a partner and managing director for Muirfield Capital Management, a $800 million hedge fund that launched in 2001 where he was involved with fixed income manager selection and distribution strategy. During that time Mr. Murray also formed and operated Pilgrim Foresight, a private investment vehicle, which offered insurance clients a tax efficient alternative investment option. From 1997 to 2001, he was a co-founding partner in Convergence Asset Management, LLC, a global fixed income fund launched with a team from Salomon's proprietary trading unit.
From 1988 to1997, Kevin was a partner at Cantor Fitzgerald, where he was responsible for managing the mortgage-backed trading operation.
In 1997, Kevin, his wife, Susan, and other interested parents formed the Autism Coalition for Research and Education which eventually became Autism Speaks in June 2005. They have three boys including Owen, who suffers from ASD. Kevin is currently an Autism Speaks Executive Board Member and holds a B.S. in Finance from Siena College.
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Director, Valerie Paradiz LLC
Dr. Paradiz is a longtime supporter of Autism Speaks having first joined the family services committee in 2012 while also serving on the Community Advisory Board. Dr. Paradiz is the director of Valerie Paradiz, LLC, a consultancy that provides technical assistance and strategic development to schools, universities, corporations and agencies that support individuals with Autism Spectrum Disorder. Prior to joining the Autism Research Institute (ARI) in her part-time capacity as Executive Director of the Autistic Global Initiative (AGI), Dr. Paradiz served as Director of Education at New York University's Asperger Institute.
Dr. Paradiz developed the 2010 International Book Award finalist in education, Integrated Self-Advocacy ISA®, an evidence-based program that gives teachers, therapists, service providers, families and people with disabilities hands-on curricula and tools to foster their ability in self-advocacy and self-determination. She is the author of the book Elijah's Cup: A Family's Journey into the Community and Culture of High-Functioning Autism and Asperger's Syndrome.
Dr. Paradiz is the 2015 recipient of the Autism Society of America's Adam Heavner Memorial Award for promoting successful employment of individuals with autism. In addition to the Autism Speaks board, she also serves on the Bank Street College of Education's Autism Annotation Board and is an NGO representative to the United Nations. She received her PhD in German Studies with honors from City University of New York's Graduate Center. Before moving fully into the field of autism, Dr. Paradiz published translations of German literature (All I Need Is Love, Klaus Kinski, Random House, 1995), as well as narrative nonfiction (Clever Maids: A History of the Grimm Fairy Tales, Perseus, 2005) while teaching writing and literature at Bard College.
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Executive Vice Chairman of the Board of Trustees, NewYork-Presbyterian Hospital
Dr. Herbert Pardes after serving from January 2000 through September 2011 as President and Chief Executive Officer of NewYork-Presbyterian Hospital and the New York-Presbyterian Healthcare System became Executive Vice Chairman of the Board of Trustees of NewYork-Presbyterian Hospital. Under his leadership, NewYork-Presbyterian Hospital escalated to one of the highest ranked hospitals and comprehensive health care institutions in the United States.
Dr. Pardes has been an outspoken proponent for academic medicine, medical research, children's health education, mental health, access to care, humanism and empathy in care delivery, Information Technology and medicine.
He has chaired three different departments of psychiatry at Downstate Medical Center, the University of Colorado and Columbia University. He served from 1989 to 2000 as the Dean of the Faculty of Medicine at Columbia University College of Physicians and Surgeons and Vice President for Health Sciences. A noted psychiatrist, he served as Director of the National Institute of Mental Health and the United States Assistant Surgeon General during the Carter and Reagan Administrations. He was also President of the American Psychiatric Association.
He is a member of the Institute of Medicine and of the American Academy of Arts and Sciences and has received the United States Army Commendation Medal as well as being the recipient of the Sarnat International Prize for leadership in the field of mental health.
He has served on commissions related to health policy appointed by Presidents George Bush and Bill Clinton including the Presidential Advisory Commission on Consumer Protection and Quality in the Healthcare Industry and the Commission on Systemic Interoperability. He serves on the NYeC Board Executive Committee for Information Technology, and is Vice Chairman of the New York Genome Center. He is former Chairman of the Greater New York Hospital Association, the Hospital Association of New York (which on whose Board he continues to sit), the Association of American Medical Colleges and the New York Association of Medical Schools.
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Vice President, White Castle System, Inc.
Richardson took his love of White Castle hamburgers to its logical extreme, joining the White Castle home office team in 1998. He serves as Vice President, White Castle System, Inc. with responsibilities for government affairs, shareholder relations, public relations and corporate philanthropy.
In recent years, Richardson has led White Castle's involvement in entertainment projects like "Harold and Kumar Go to White Castle", "Undercover Boss" and "Impractical Jokers". Richardson is frequently quoted in major print and broadcast media on restaurant industry perspectives on current events and policy issues. He serves on the board of Family Enterprise USA, the National Council of Chain Restaurants and the Ohio Restaurant Association where he serves as Vice Chairman of the Board. In 2014, Richardson was named the National Restaurant Association's "Advocate of the Year".
Richardson is active in his community, serving on a number of charity boards. He is Chairman of the Board for the American Red Cross of Greater Columbus, Ohio, and serves on the YMCA of Central Ohio board, as well as the American Red Cross National Philanthropy Board.
Richardson has demonstrated a powerful passion and commitment to Autism Speaks over the past several years, spearheading the White Castle efforts that have raised over $3.5 million dollars. He has testified before the Ohio State House of Representatives and worked with Autism Speaks board member Laura Slatkin to create the "Original Slider" White Castle hamburger scented candle – an effort that has raised awareness and over $350,000 for Autism Speaks.
As a 4th generation family member "in-law" Jamie invests his time and passion in the White Castle vision of "remaining a family owned business for generations to come. Jamie and his wife Kate live in Mount Vernon, Ohio and have five children, Brendan, Chloe, Mary, Grace, Maggie and Finn.
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President and CEO, BBDO Worldwide
Andrew Robertson has been President and Chief Executive Officer of BBDO Worldwide since June 2004.
BBDO Worldwide adds value to its clients' brands and businesses through its focus on "The Work, The Work, The Work." It has been named Network of the Year at Cannes five times and is currently the world's most awarded agency network according to The Gunn Report and the Most Creative Network across all communications platforms in the Directory Big Won. Since 2005, BBDO has been honoured as Global Agency of the Year in Ad Age, Adweek (two times) and Campaign (four times). In 2011, BBDO Worldwide was also recognized as the Most Effective Network in the world by the Global Effies.
Andrew first came to BBDO in the UK in 1995, joining Abbott Mead Vickers BBDO where he subsequently served as Chief Executive. In 2001, he moved to BBDO North America to serve as President and CEO.
He began his advertising career at Ogilvy & Mather, London as a Media Planner. He switched to Account Management and was appointed to the Board of Ogilvy & Mather in 1986. In 1989, he joined J. Walter Thompson and in November 1990, was appointed Chief Executive of WCRS.
Andrew has a degree in Economics from City of London University. He currently serves on the Boards of Autism Speaks, the Center on Media and Child Health, the International Rescue Committee and Wake Forest University Business School. He is a past Chairman of The Advertising Council.
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President of Program Strategy and Chief Operating Officer, FX Networks
Chuck Saftler is President of Program Strategy and Chief Operating Officer of FX Networks and oversees programming strategies including scheduling and acquisitions, program operations, business operations and digital operations for FX, FXX and FXM. In addition, Saftler oversees special programs/hosted content including FX's The Download, all award show coverage including FXX's The Creative Arts Emmys and FXM's Red Carpet coverage, FXX's new late night Animation Domination block and, in conjunction with FX Digital Marketing, the new video-on-demand app FXNOW featuring Simpsons World.
Saftler has the longest tenure of any FX Networks employee, having joined FX in December of 1993 as Director of Scheduling, seven months prior to the network's launch. In addition to being a member of the FX launch team, he also helped launch Fox Movie Channel in its original incarnation as fXM in October of 1994. He was promoted to Vice President of Programming in 1996, and then to Senior Vice President of Programming at FX in June 2000. He added General Manager of Fox Movie Channel to his responsibilities in July 2003, and was promoted to Executive Vice President of FX Networks in 2006. Saftler assumed his current role in 2013.
Saftler has played an enormous role in the growth and expansion of FX Networks. He has been responsible for assembling the most impressive movie library of any broadcast or basic cable network on television – a collection that includes the highest number of box-office hit films and the most commercial television premieres of any network. He is also responsible for acquired television series deals for FX Networks, including Two and a Half Men, Mike & Molly and How I Met Your Mother.
Saftler spearheaded the transformation of FXM from Fox Movie Channel and has expanded its growing library of award-winning hit and prestige films. He also oversees the development of the network's original programming.
In September 2013, Saftler helped launch FX Networks' newest channel FXX. He negotiated the landmark deal for the linear and non-linear rights to The Simpsons for FXX, including the groundbreaking 12-day "Every Simpsons Ever" marathon that helped make FXX basic cable's fastest-growing entertainment network in primetime last year. Working with FX Digital Marketing, Saftler oversaw the creation of the acclaimed Simpsons World for FXNOW. He negotiated the rights to broadcast the Primetime Creative Arts Emmy Awards on FXX. He is also developed the late night animation block Animation Domination for the network with ADHD Studio.
Prior to joining FX, Saftler worked in various program research positions at KTLA-TV in Los Angeles, as well as at Columbia Pictures Television, where he participated in the successful syndicated launches of Seinfeld and Married…With Children. He is a member of both the national and local Los Angeles Board of Directors for Autism Speaks. He is a graduate of Boston University and currently serves on the National Boston University Alumni Council.
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Stuart Savitz
Founder, Law Offices of Stuart M. Savitz, LLC Operating Board, CP Acquisition LLC
Stuart Savitz graduated from Michigan State University (James Madison College) with a BA in 1982, and received his JD from Washington University School of Law in St. Louis in 1985. In 2001, Savitz founded the Law Offices of Stuart M. Savitz LLC, specializing in mergers and acquisitions, corporate finance transactions and general corporate services. In 2004, Savitz was the lead investor in CP Acquisition LLC, which acquired the Coco Pazzo and Coco Pazzo Café restaurants in Chicago.
Stuart, and his wife Amy, live in Glencoe, Illinois, with their two sons, Tyler, who has autism, and Spencer. In 2007, Spencer founded Team Tyler to participate in the Chicago Walk Now for Autism Speaks. In 5 years, Team Tyler has raised over $600,000. In 2011, Spencer and the Savitz Family founded the North Shore Walk, which has raised almost $400,000 in its first two years.
The Savitz' began funding autism research through Cure Autism Now in 2005, and have continued their funding through Autism Speaks. Mr. Savitz has also served on the Autism Speaks Family Services Committee since 2010.
Mr. Savitz served on the Foundation Board for Children's Memorial Hospital in Chicago from 2004 – 2009.
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Dan Schulman
President, PayPal and Chairmen, Symantec
Dan Schulman is President of PayPal and Chairmen of Symantec. He previously served as Group President of Enterprise Growth at American Express from 2010 to 2014. He was responsible for the company's global strategy to expand alternative mobile and online payment services, form new partnerships and build revenue streams beyond the traditional card and travel businesses.
Schulman joined American Express from Sprint Nextel Corporation, where he served as President of Sprint's Prepaid group since 2009. Before joining Sprint, Schulman was the founding CEO of Virgin Mobile USA, a mobile virtual operator, acquired by Sprint in 2009. Prior to that he was CEO of priceline.com and spent the early part of his career with AT&T, where he ultimately led the company's consumer long distance business.
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Clinical Assistant Professor, Ammon School of Education, Adelphi University
Dr. Shore is a clinical assistant professor at the Ammon School of Education at Adelphi University teaching courses in special education and autism. Before his election to the Board of Directors Dr. Shore served on the Autism Speaks Family Services committee.
Dr. Shore focuses his work on matching well-thought out educational practices to individual needs that promote fulfilling and productive lives for those with autism. It is because of his personal experiences when he was nonverbal and his parents refused to institutionalize him that Dr. Shore has become an advocate of intensive early intervention matched to the needs of the individual with autism. He speaks and consults throughout the world on educational and social inclusion, sensory processing challenges, bullying, as well as many other issues associated with successful transitioning into adulthood for those with autism.
Dr. Shore's writings can regularly be seen in the media. He also shares his experiences in his autobiography Beyond the wall: Personal experiences with autism and Asperger Syndrome, Ask and tell: Self-advocacy and disclosure for people on the autism spectrum, and the DVD Living along the autism spectrum: What is means to have autism or Asperger Syndrome.
In addition to his work with Autism Speaks, Dr. Shore serves as President emeritus of the Asperger/Autism Network. He also serves on the board of Specialisterne-USA, the Asperger Syndrome and High Functioning Autism Association, the United States Autism and Asperger Association, and is the President of the Asperger Syndrome Support Network of the Russian Federation.
Dr. Shore received his Ed.D. in Special Education from the Boston University School of Education in 2008.
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Founder and Executive Chairman, Nest Fragrances
After a 13-year career as a successful Wall Street executive, Laura Slatkin left the world of finance in 1992 to pursue a very different business venture: Slatkin & Co., a luxury home fragrance brand she founded with her husband, Harry Slatkin. Its high-quality, smartly designed collections established it as the most successful luxury home fragrance brand to-date, blazing a trail to a now-multi-billion dollar category in the beauty industry. In 2005, the couple sold the popular brand, even as Laura's interest in fragrance continued to grow.
That same year, Laura founded her own company, NEST Fragrances, initially focusing on the production of private-label and licensed home fragrance collections for the world's most important luxury brands including Christian Dior, Ralph Lauren, Tory Burch, Jonathan Adler and NARS. In 2008, after three years of meticulous development, she launched a more personal collection of luxe home scents by the same name, the NEST Fragrances Collection. For this collection, Laura draws upon her own experiences, emphasizing the powerful emotional connection between scent and a sense of place: "As guests enter my home and they are greeted with a beautiful home fragrance, their faces light up, and their mood changes. An immediate emotional reaction takes place and they are impacted in a very positive way," she said. It is with this spirit and intent that all of NEST Fragrances' scents recreate both faraway and familiar atmospheres.
Naturally, personal fragrance followed: In 2012, Laura launched the NEST Fine Fragrances Collection. Comprised of sophisticated botanical notes in unexpected combinations and exquisitely designed packaging, each eau de parfum in the collection continues to evolve the brand.
Outside of the fragrance world, Laura is committed to various causes, most notably autism, as her son was diagnosed with this life-altering disorder. Along with her husband and closest colleagues, she co-founded New York Collaborates for Autism (NYCA), an organization dedicated to creating replicable programs that immediately address the needs of individuals and families living with Autism Spectrum Disorder (ASD). To date, it has created the first charter school dedicated to autism; a training institute with Hunter College; a clinical research institute- the Center for Autism and the Developing Brain in collaboration with New York Presbyterian Hospital, Weil Cornell and Columbia University.
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President and Chief Support Officer, Staples Europe
John B. Wilson joined the board of Autism Speaks in February 2007, following the merger with Cure Autism Now (CAN) and has been an active board member since 2000. Wilson is the President of Staples Europe and is the owner and president of Hyannis Port Capital, Inc. He has held several other executive positions, including Chief Operating Officer and executive vice president of Gap, Inc.; Chief Financial Officer and executive vice president of Staples, Inc.; senior vice president of Northwest Airlines; and vice president/partner at Bain & Company. He serves on the board of several Franklin Templeton Mutual Funds as well as a number of private company boards.
Wilson earned his MBA from Harvard Business School in 1983 and his Bachelor of Science degree in Chemical Engineering, magna cum laude, from Renssalaer Polytechnic Institute in 1981. Wilson and his wife Leslie have been married for 25 years and have three children.
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Former COO International, S.C. Johnson & Son, Inc.
Steven P. Stanbrook joined S.C. Johnson in November 1996 as President, Europe, and one year later, Africa & the Near East were added to his responsibilities. In July 2006, he was appointed President – Developing Markets and in September 2010 to Chief Operating Officer – International, where he covered 130 markets, representing roughly two-thirds of SCJ's Global sales. Steven joined SC Johnson from CompuServe where he served as President of its International Division. Before CompuServe, Steven spent 17 years at Sara Lee Corporation, most recently as President & CEO of Sara Lee Bakery.
Steven also serves on the Board of Directors of Imperial Brands, the U.K.'s twelfth largest enterprise, and is a partner at the Chicago-based Private Equity firm Wind Point Partners. Previous Board roles have included Hewitt Associates and Chiquita Brands International, both NYSE listed businesses.
Steven and his wife, Judy, have 5 children aged 23-30 years.
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Joseph T. Coyle, M.D.
Director, Laboratory for Psychiatric and Molecular Neuroscience, Mclean Hospital
Eben S. Draper Professor of Psychiatry, Harvard Medical School
Joseph T. Coyle, MD, is the Eben S. Draper Chair of Psychiatry and Neuroscience at Harvard Medical School and was chairman of the Consolidated Department of Psychiatry at Harvard 1991-2001. A graduate of College of the Holy Cross, he received his MD from Johns Hopkins. He completed an internship in pediatrics, a residency in psychiatry, and a fellowship with the Nobel laureate Julius Axelrod, PhD. He joined the Hopkins faculty in 1975 and was named the Distinguished Service Professor of Child Psychiatry in 1985. Dr. Coyle is a member of the Institute of Medicine (1990), a fellow of the American Academy of Arts and Sciences (1993), and a distinguished fellow of the American Psychiatric Association. He is past president of the American College of Neuropsychopharmacology (2001) and of the Society for Neuroscience (1991). He is the editor of JAMA Psychiatry.
Dr. Coyle and his wife, Genevieve, have 3 sons.
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Bob Wright
Co-founder, Autism Speaks
Senior Advisor, Lee Equity Partners
Bob Wright served as Vice Chairman and Executive Officer, of the General Electric Company and also Chairman and Chief Executive Officer of NBC Universal. Bob joined NBC as President and Chief Executive Officer on September 1, 1986, and served as Chairman and Chief Executive Officer of NBC Universal until May 1, 2007. Bob had one of the longest and most successful tenures of any media company chief executive, with more than two decades at the helm of one of the world's leading media and entertainment companies. He has a strong history of philanthropy and community service, for which he has received numerous awards and accolades. He serves on the boards of Polo Ralph Lauren Corporation, AMC Networks Inc., and is a Trustee of the New York Presbyterian hospital. He is also Chairman and CEO of the Palm Beach Civic Association and Senior Advisor of THL Capital. Bob Wright is also the former member of the Executive Committee of Rand Corporation and a former Board of Director of EMI Group Global Ltd. He is a graduate of the College of the Holy Cross and of the Law School of University of Virginia.
The Wrights have three children and six grandchildren.
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Clinica Santa Barbara
Clinical and mobile hospitals / clinics
Reclaim business
Address and Phones Clinica Santa Barbara
La Isabelica, Valencia, Carabobo - Venezuela
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Days and Hours of Service Clinica Santa Barbara
Monday, Tuesday, Wednesday, Thursday, Friday
Morning: 08:00 am - 12:00 am
Afternoon: 01:00 pm - 5:00 pm
Afternoon: 01:00 pm - 5:00 pm
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Putnam, 1972 - Comics & Graphic Novels - 226 pages
Fifteen works by the American artist and author provide a journey into a macabre world
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Review: Amphigorey (Amphigorey #1)User Review - Milica Chotra - Goodreads
Lovely collection of Gorey's illustrated short stories. Or rather: a collection of his wonderful illustrations (certainly worth a thousand words) with funny text here and there :) And while it's dark ... Read full review
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Review: Amphigorey (Amphigorey #1)User Review - Tammie - Goodreads
I really enjoyed "Amphigorey", which is a collection of 15 books first published between 1953-1965. "Gashlycrumb Tinies", "The Listing Attic" and "Wuggly Ump" are a few of my favorites titles in this unique and sometimes bizarre book. Read full review
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PROJECT SUK/IH/IARY (See instructions): The progressive growth of primary ovarian cancer and metastasis is dependent on development of an adequate blood supply (angiogenesis). Vascular endothelial growth factor (VEGF) plays a critical role in angiogenesis and consequent ovarian cancer growrth and progression. VEGF blockade has shown promise in human studies. Our pre-clinical and clinical results from the prior funding period demonstrate that a novel approach (high-affinity VEGF decoy receptor, VEGF-Trap or aflibercept) for VEGF blockade was highly effective in combination with taxane chemotherapy. However, despite initial responses, most patients eventually develop tumor progression resulting in their demise, mainly due to the development of drug resistance. The DII4 (delta-like ligand 4)/Notch signaling pathway has recently been shown to play an important role in angiogenesis including vessel maturation, pericyte recruitment, branching and cell differentiation, proliferation, survival and apoptosis. Our preliminary data indicate that when DII4 inhibition using a monoclonal antibody (DII4-mAb or REGN421) was coupled with VEGF inhibition (aflibercept), this combination strikingly reduced tumor burden and ascites, suggesting that this anti-angiogenesis regimen holds promise as a novel therapeutic modality. However, the mechanisms of its potency are not fully understood. We hypothesize that the DII4/Notch signaling pathway plays an important role in reducing the efficacy of anti-VEGF monotherapy and targeting both VEGF and DII4/Notch signaling pathway will enhance anti-angiogenic therapy. The overall goal of this proposal is to develop novel and effective strategies for targeting ovarian cancer angiogenesis. In the current proposal, we will investigate the functional significance of DII4/Notch signaling pathway in ovarian cancer by examining whether DII4 expression in ovarian cancer cells activates Notch signaling in endothelial cells and whether blockade of DII4/Notch signaling with REGN421 deregulates angiogenesis in vitro in Aim 1.
In Aim 2, we will assess the efficacy of combinatorial approaches for targeting VEGFA/EGFR/DII4/Notch signaling pathway with aflibercept and REGN421 using in vivo orthotopic ovarian cancer models. We will conduct a Phase I/lb clinical trial using the anti-DII4 monoclonal antibody REGN421 in patients with recurrent ovarian carcinoma in Aim 3. Thus, all three Aims are complementary to each other and findings of this study should allow the design of new therapeutic approaches for women with ovarian cancer
There are limited options for treating advanced/recurrent ovarian cancer. Anti-angiogenic therapies appear to be one of the most promising for treatment strategies for ovarian and other cancers;however, despite initial responses, most patients eventually develop progressive disease. DII4/Notch signaling is increased in response to elevated VEGF levels and DII4 expression is increased in the tumor vasculature. DII4 blockade especially in combination with anti-VEGF therapy, appears to be a highly promising approach.
|Bottsford-Miller, Justin; Choi, Hyun-Jin; Dalton, Heather J et al. (2015) Differential platelet levels affect response to taxane-based therapy in ovarian cancer. Clin Cancer Res 21:602-10
|Sun, Yan; Hu, Limei; Zheng, Hong et al. (2015) MiR-506 inhibits multiple targets in the epithelial-to-mesenchymal transition network and is associated with good prognosis in epithelial ovarian cancer. J Pathol 235:25-36
|Wen, Yunfei; Graybill, Whitney S; Previs, Rebecca A et al. (2015) Immunotherapy targeting folate receptor induces cell death associated with autophagy in ovarian cancer. Clin Cancer Res 21:448-59
|Previs, Rebecca A; Coleman, Robert L; Harris, Adrian L et al. (2015) Molecular pathways: translational and therapeutic implications of the Notch signaling pathway in cancer. Clin Cancer Res 21:955-61
|Zhang, Shu; Lu, Zhen; Unruh, Anna K et al. (2015) Clinically relevant microRNAs in ovarian cancer. Mol Cancer Res 13:393-401
|Zhang, Shiwu; Mercado-Uribe, Imelda; Liu, Jinsong (2014) Tumor stroma and differentiated cancer cells can be originated directly from polyploid giant cancer cells induced by paclitaxel. Int J Cancer 134:508-18
|Matsuo, Koji; Sheridan, Todd B; Mabuchi, Seiji et al. (2014) Estrogen receptor expression and increased risk of lymphovascular space invasion in high-grade serous ovarian carcinoma. Gynecol Oncol 133:473-9
|Liu, Guoyan; Sun, Yan; Ji, Ping et al. (2014) MiR-506 suppresses proliferation and induces senescence by directly targeting the CDK4/6-FOXM1 axis in ovarian cancer. J Pathol 233:308-18
|Rich, Thereasa A; Liu, Mei; Etzel, Carol J et al. (2014) Comparison of attitudes regarding preimplantation genetic diagnosis among patients with hereditary cancer syndromes. Fam Cancer 13:291-9
|Zhang, S; Mercado-Uribe, I; Xing, Z et al. (2014) Generation of cancer stem-like cells through the formation of polyploid giant cancer cells. Oncogene 33:116-28
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