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Tagliabue hurts NFL case, rips Saints' coaches, may foster more suits
The NFL will make the case that some major findings were upheld by Paul Tagliabue's ruling on the appeal of the player suspensions in the Saints' "bounty" case, but the reality is that the former commissioner poked some significant holes in the league's allegations and made it clear that had he been running this investigation things would not have been nearly as draconian as what Goodell handed down. In doing so, Tagliabue may have bolstered the case for additional litigation in this case, with sources indicating to me that Scott Fujita and Anthony Hargrove could end up pursuing lawsuits similar to Jonathan Vilma's ongoing case against the commissioner and the league.
|More on Bountygate
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As all sides digested the 22-page ruling, it will no doubt become a critical document moving forward. Goodell's reputation among players, which has been sinking in recent months, will take a further hit here. One cannot help but wonder if there is reshuffling within the NFL offices, as well, as fallout mounts. Goodell brought new faces into his inner circle in recent years, with some longtime NFL confidants no longer in the office on a daily basis. Some league insiders have mentioned to me throughout the duration of this "bounty" saga that this may have been handled very differently had some of those old heads still been as heavily involved, going back to the original language and tone set by press releases on Goodell's rulings, as well as the letter sent to teams updating them on the matter. Most certainly today's ruling chips away at the idea of the complete power of the commissioner to navigate the terms of such player discipline moving forward.
No doubt that issue has strained relationships between the league office and the Saints -- with the denial of coach Sean Payton's contract extension another touchstone issue -- and executives from other teams have commented privately that perhaps the league office has been overzealous in its dealings with team matters. This decision possibly could lead to smoothing out some of those feelings, and may impact the manner with which the league communicates with teams on sensitive issues. The upcoming year could define Goodell's legacy, with these bounty lawsuits possibly lingering for some time, as well as the collusion suits still ahead, and the class-action concussion lawsuits, while the battle over HGH testing rages on and will lead the NFL and NFLPA back to Washington on Wednesday.
No one could argue that Tagliabue, one of Goodell's mentors, raised significant questions with key evidence and witnesses in this case and the commissioner's decisions on player discipline. Tagliabue makes the case that Fujita did not engage in "conduct detrimental," and never should have been suspended. He makes the case that Hargrove probably warranted a fine for obstructing the process to some degree, but not a suspension. He implies that players are taught to listen to coaches -- it's ingrained in them -- and to level such historic punishments for what appears to be much more of a pay-for-performance program than a bounty targeting specific players, is unjust.
Hargrove and Fujita may stand to gain the most. Hargrove missed an entire season in large part because his status was so nebulous for so long as these appeals and decisions played out. He lost a shot at a year of salary, a year of benefits, an accrued season for pension. He lost the chance to keep playing football and putting plays on tape that could lead to future contracts and aid his position as a free agent (having signed a one-year deal with green Bay prior to his release). As someone who was already in the league's substance-abuse program, he had his character attacked, claims made about what he allegedly said on the field -- that seems untrue -- and as Tagliabue notes the NFL could not even make clear exactly what was asked of him by investigators. It's way too late to expect to catch on with a team now, so 2012 was taken away from him. This ruling doesn't give it back and the only way to gain restitution and damages would be through the courts -- and I would not be surprised in the least if there were no shortage of lawyers eager to take on that case after reading this ruling.
Fujita isn't even included among the other three players in the conclusion section at the very end of the ruling, as Tagliabue notes only Hargrove, Will Smith and Vilma engaged in "conduct detrimental to the integrity of, and public confidence in, the game of professional football." Fujita was resolute throughout this matter that he never took part in pay to injure and Tagliabue affirms that. He was there for only one season of the program (2009) yet was somehow among the four players plucked from that entire defensive roster and facing suspension.
With his career now likely over because of a neck condition that landed him on IR with the Browns, Fujita spent his final weeks in the NFL having to defend himself from these allegations. He happens to be represented by agent Don Yee, an accomplished lawyer who also represents Payton. If Fujita were to decide to pursue recourse against the league, he would seem to be incredibly well positioned.
Smith has told other players he has been mulling a lawsuit as well, and as someone who went through a similar ordeal during the STARCAPS case, some are taking him at his word.
Obviously, Vilma will continue to pursue his case against Goodell. The fact that Tagliabue could not confirm the league's allegation of Vilma having money in his hand prior to the 2009 NFC Championship Game, among other things, would seem to help his case, saying "there was no evidence" of any player paying money to injure an opponent in that game and that there was no evidence that Vilma's speech in way led to "causing misconduct on the playing field."
The overall tone of Tagliabue's ruling points very negatively at the Saints staff and front office for overseeing such a program. Yet, it must be noted, he did not speak to GM Mickey Loomis or Payton as part of the appeal process. So for as much as anyone might say this ruling negatively impacts them, it must be noted the role they played once Tagliabue took over the appeal was scant. And Payton never met with investigators until March, sources said, while the investigation had long been going on, so his degree of obstruction could be argued as well.
Most suspect the Saints eventually will get Payton signed to a contract extension. If not, Goodell would be in the uncomfortable position of having to rule on whether the final year of his existing contract tolls into 2013. If he rules it does, the league could be sued by one of its best coaches. If he doesn't, he most certainly would be looking at getting sued by an owner. Neither is desirable and makes 2013 potentially all the more interesting for the league office.
Gregg Williams could be the biggest loser in all of this. As Tagliabue notes the coaches cannot appeal their discipline and Williams is still hoping for reinstatement after the Super Bowl. Given the tone of this document, the league very well could continue his suspension. After having so much of its discipline in this case muted, Williams would be an easy target with which to make a point. The league could latch on to statements from Tagliabue like, "I strongly condemn the misconduct of the Saints' coaches, and this entire case has been contaminated by the coaches and others in the Saints organization." Tagliabue clearly takes issue with the wording of slides and motivation material the defensive staff provided to players as well that was included as evidence.
One could argue the already unprecedented penalties given to Williams and Payton were enough, but given all of the time and effort the league put into this case, and how staunchly it stood behind its findings even as parts of the case seemed to be crumbling -- now coupled with this ruling on player discipline -- perhaps the NFL digs in its heels even more on Williams. Some wonder if his suspension gets extended by another year -- regardless, expect the ramifications of this entire episode to linger and resonate for quite some time.


text:
CFW's 2009 statistics from Kenya have been released. We are pleased to report that the CFW network served over 500,000 people in 2009 through in-store sales and outreach activities. We've uploaded a chart of summary statistics so that you can see the effect that CFW is having in fighting prevalent diseases such as malaria in Kenya. More detailed statistics are available on our website; we've included a link below.
Project Reports on GlobalGiving are posted directly to globalgiving.org by Project Leaders as they are completed, generally every 3-4 months. To protect the integrity of these documents, GlobalGiving does not alter them; therefore you may find some language or formatting issues.
If you donate to this project or have donated to this project, you will get an e-mail when this project posts a report. You can also subscribe for reports via e-mail without donating.
We'll only email you new reports and updates about this project.

subset: commoncrawl


text:
347. calusakat
Quoting AEKDB1990:
Yes, they did, in leaked e-mail communications between each other. I am not surprised you feign not knowing. Apparently you don't read much except for left leaning blogs.
The standard news media has repeatedly reported on statements by several agencies that they routinely alter data.
Nobody is lying, you are simply sadly mistaken.
Member Since: December 31, 1969 Posts: Comments:


text:
Gift Premium Subscription To mpc88
Join Date:07-11-2013
Last Activity:09-29-2013 10:58 PM
Likes Given: 41
3 Likes on 3 Posts
Posted in thread: Beer brewing for the meme generation on 08-30-2013 at 03:32 AM
Yup it's done and long gone drank (took some time though!).If you go to page 6 of the thread
and scroll towards the middle, I put up the other video of me actually reviewing the beer.lol,
I just saw t...
Posted in thread: How many bottles do you have? on 08-20-2013 at 11:46 PM
240. Its what I can fit in this (4-drawer legal-size filing cabinet): my....now that is
something I NEVER thought of at all, :)
Posted in thread: How many bottles do you have? on 08-20-2013 at 11:44 PM
Well over 2,000 last time I counted. I know it's excessive but I can't bring myself to throw
away perfectly good bottles. Oh well, I guess I could have worse neurotic tendencies than
bottle hoarding.....
Posted in thread: How many bottles do you have? on 08-18-2013 at 11:22 PM
Wow, I only have like 30 some odd PETs because of my Coopers kit and I'm just starting off.
That AND my apartment's too small for any more bottles. I'll probably end up buying me a keg so
I can just k...
Posted in thread: went to my first homebrew club meeting tonight on 08-14-2013 at 09:57 AM
Nice. I would like to do the same, but I think alot of the local brewers are pretty far from
me. Will have to just go the length to join the club though. Congrats, :):tank:
Posted in thread: Remember when... on 08-13-2013 at 11:26 PM
Remember when they actually had music videos on MTV, and not all that "reality" crap they have
on it now?I remember people actually cooking on the Food Network, instead of,
Posted in thread: Am I over-reacting? Safety issue.. on 08-13-2013 at 11:23 PM
Please tell me more about these unlicensed doctors and lawyers. Provide links where possible.
;)well, there is that doctor from Pennsylvania, who just went to trial from aborting babies
without a lice...
Posted in thread: what podcasts do you listen to? on 08-13-2013 at 09:44 PM
some NPR podcasts like Fresh AirBarbara Simpson from KSFO(her voice makes me sleepy)Michael
Colameco for cooking tipsDr. Ronald Hoffman for health tips, advice, updates, Local Gardening
show for tips ...
Posted in thread: Beer brewing for the meme generation on 08-13-2013 at 05:33 AM
what an awesome video, how did it turn out or are you still waiting? it's amber ale so I
figured by now it should still be around, right? either way cheers, :)
Posted in thread: Easy Partial Mash Brewing (with pics) on 08-13-2013 at 05:20 AM
Nice. I will try this after I get a couple more batches done, :)


text: His revolutionary designs stretches at the dawn of the eighties, gum-printed tulles, wool woven then embroidered and charred. Based on the mastering of new materials, his creativity meets discoveries of physics or mechanics, just as in those textiles in origami that are unbendable, only stretchable. Beyond his dazzling technical skills, he remains an architect and a poet, following his road, between ���structuration��� and creativity. Thus, through his eau de parfum, imposing beauty as absolute once more, Azzedine Ala��a���s enchanted universe goes on, as he offers, in a truly baudelairian gesture, an immortal invitation to the voyage.


text:
If an imap server returns a namespace that begins with a hierarchy delimiter, in order to distinguish that namespace from a personal folder with the same name, then our IMAP code gets very confused, and shows each level in the hierarchy as a top level folder.
Created attachment 276019 [details] [diff] [review]
proposed fix
this fixes the problem so such folders are at least usable. We're still not doing things exactly right - we should be creating a munged directory name for the "/home" container .sbd file instead of "home.sbd", e.g., "338384.sbd" so we'll have issues if the user has a "home" folder as well. But this is much better than the previous behavior.
the basic problem is fixed - we'll let this bake on the trunk. Might be good for a 2.0.0.x release...
fix landed for 220.127.116.11


text: Having been to STaR multiple times, we have never been disappointed. Chef Jonathan and his wife, Deborah, are the consummate hosts who have you feeling like you are having dinner in their home - not in a restaurant. Service and hospitality are impeccable. To say the food is delicious is an understatement. Chef Jonathan explains how he prepares each dish... More


text:
Research Topics
Genomes and Genes
Gene Symbol: RS1
Description: retinoschisin 1
Alias: XLRS1, X-linked juvenile retinoschisis protein, retinoschisin
Species: human
Top Publications
Research Grants
Scientific Experts
Detail Information
Publications156 found, 100 shown here
- Defective discoidin domain structure, subunit assembly, and endoplasmic reticulum processing of retinoschisin are primary mechanisms responsible for X-linked retinoschisisWinco W H Wu
Department of Biochemistry and Molecular Biology, University of British Columbia, Vancouver, British Columbia, Canada
J Biol Chem 278:28139-46. 2003b>Retinoschisin is a 24-kDa discoidin domain-containing protein that is secreted from photoreceptor and bipolar cells as a large disulfide-linked multisubunit complex...
- Inactivation of the murine X-linked juvenile retinoschisis gene, Rs1h, suggests a role of retinoschisin in retinal cell layer organization and synaptic structureBernhard H F Weber
Institute of Human Genetics, Biocenter, University of Wurzburg, D 97074 Wurzburg, Germany
Proc Natl Acad Sci U S A 99:6222-7. 2002Deleterious mutations in RS1 encoding retinoschisin are associated with X-linked juvenile retinoschisis (RS), a common form of macular degeneration in males...
- Novel XLRS1 gene mutations cause X-linked juvenile retinoschisis in Chinese familiesXiang Ma
Eye Center of Peking University, People s Hospital, Peking University, Beijing, People s Republic of China
Jpn J Ophthalmol 52:48-51. 2008To investigate various XLRS1 (RS1) gene mutations in Chinese families with X-linked juvenile retinoschisis (XLRS or RS).
- Relation of response to treatment with dorzolamide in X-linked retinoschisis to the mechanism of functional loss in retinoschisinSaloni Walia
Department of Ophthalmology and Visual Sciences, University of Illinois at Chicago, Chicago, Illinois, USA
Am J Ophthalmol 147:111-115.e1. 2009..if a positive response of macular cysts to treatment with dorzolamide eye drops in patients with juvenile X-linked retinoschisis (XLRS) can occur with mutations that result in different types of retinoschisin protein dysfunction.
- A novel truncating Rs1 mutation associated with X-linked juvenile retinoschisisZi Bing Jin
Jpn J Ophthalmol 51:71-3. 2007
- Assessment of RS1 in X-linked juvenile retinoschisis and sporadic senile retinoschisisA Gehrig
Institut fur Humangenetik, Biozentrum, Universitat Wurzburg, Germany
Clin Genet 55:461-5. 1999The RS1 gene is the causative gene in X-linked juvenile retinoschisis (RS). We have screened this gene for mutations in 13 patients with RS and in 7 probands with senile retinoschisis, a sporadic, later-onset form of retinoschisis...
- Two Japanese patients with mutations in the XLRS1 geneDemidmaa Tuvdendorj
Department of Ophthalmology, Kagoshima University Faculty of Medicine, Kagoshima, Japan
Retina 22:354-7. 2002
- Two novel point mutations of the XLRS1 gene in patients with X-linked juvenile retinoschisisYumiko Inoue
Department of Ophthalmology and Visual Science, Osaka University Graduate School of Medicine, Japan
Am J Ophthalmol 134:622-4. 2002To report two novel point mutations of the XLRS1 gene in two Japanese patients with X-linked juvenile retinoschisis.
- Genetic and clinical evaluation of juvenile retinoschisisJudy E Kim
Department of Ophthalmology, Medical College of Wisconsin, Milwaukee, Wisconsin 53226, USA
J AAPOS 13:215-7. 2009Juvenile retinoschisis is a rare retinal dystrophy caused by RS1 gene mutations...
- Unusual manifestations of x-linked retinoschisis: clinical profile and diagnostic evaluationDhananjay Shukla
Aravind Eye Hospital and Postgraduate Institute of Ophthalmology, Madurai, Tamil Nadu, India
Am J Ophthalmol 144:419-423. 2007..To describe the unusual clinical manifestations and diagnostic evaluation of X-linked retinoschisis (XLR)...
- Novel RS1 mutations associated with X-linked juvenile retinoschisisJunhui Yi
Department of Ophthalmology, The Third Xiangya Hospital, Central South University, Changsha 410013, PR China
Int J Mol Med 29:644-8. 2012To identify mutations in the retinoschisin (RS1) gene in families with X-linked retinoschisis (XLRS). Twenty families with XLRS were enrolled in this study...
- Phenotypic expression of X-linked retinoschisis in Chinese families with mutations in the RS1 geneFei Xu
Department of Ophthalmology, Peking Union Medical College Hospital, Peking Union Medical College and Chinese Academy of Medical Sciences, Shuai Fu Yuan, Beijing, China
Doc Ophthalmol 123:21-7. 2011..Genomic DNA was extracted from peripheral leukocytes. All exons and the flanking introns of the RS1 gene were amplified by polymerase chain reaction and screened for mutations by direct DNA sequencing...
- Retinoschisin (RS1), the protein encoded by the X-linked retinoschisis gene, is anchored to the surface of retinal photoreceptor and bipolar cells through its interactions with a Na/K ATPase-SARM1 complexLaurie L Molday
Department of Biochemistry and Molecular Biology, Centre for Macular Research, University of British Columbia, Vancouver, British Columbia, Canada
J Biol Chem 282:32792-801. 2007b>Retinoschisin or RS1 is a discoidin domain-containing protein encoded by the gene responsible for X-linked retinoschisis (XLRS), an early onset macular degeneration characterized by a splitting of the retina...
- Intracellular retention of mutant retinoschisin is the pathological mechanism underlying X-linked retinoschisisTao Wang
Department of Medical Genetics, Cambridge Institute for Medical Research, University of Cambridge, Addenbrooke s Hospital, Hills Road, Cambridge CB2 2XY, UK
Hum Mol Genet 11:3097-105. 2002..Many missense and protein truncating mutations of the causative gene RS1 (encoding retinoschisin) have been identified but disease severity is not mutation-dependent...
- Novel mutations in XLRS1 causing retinoschisis, including first evidence of putative leader sequence changeK T Hiriyanna
Department of Ophthalmology and Visual Sciences, Kellogg Eye Center, University of Michigan, Ann Arbor 48105, USA
Hum Mutat 14:423-7. 1999Juvenile retinoschisis is an X-linked recessive disease caused by mutations in the XLRS1 gene...
- Retinoschisin, the X-linked retinoschisis protein, is a secreted photoreceptor protein, and is expressed and released by Weri-Rb1 cellsC Grayson
Department of Medical Genetics, The Wellcome Trust Centre for Molecular Mechanisms in Disease, Cambridge Institute for Medical Research, University of Cambridge, Addenbrookes Hospital, Hills Road, Cambridge CB2 2QQ, UK
Hum Mol Genet 9:1873-9. 2000..RS1 encodes a 224 amino acid protein, retinoschisin, which contains a discoidin domain but is of unknown function...
- Genetic variations in the hotspot region of RS1 gene in Indian patients with juvenile X-linked retinoschisisBalasubbu Suganthalakshmi
Department of Genetics, Aravind Medical Research Foundation, Madurai, India
Mol Vis 13:611-7. 2007..This condition is caused by mutations in the RS1 gene and is, characterized by schisis within the retina...
- ERG variability in X-linked congenital retinoschisis patients with mutations in the RS1 gene and the diagnostic importance of fundus autofluorescence and OCTAgnes B Renner
Augenklinik, Charite Campus Benjamin Franklin, Universitatsmedizin Berlin, Hindenburgdamm 30, 12200 Berlin, Germany
Doc Ophthalmol 116:97-109. 2008X-linked congenital retinoschisis (RS) is a relatively frequent retinal dystrophy associated with RS1 gene mutations. A negative electroretinogram (ERG), i.e., a b/a wave ratio <1...
- X-linked retinoschisis: an updateStephen K Sikkink
Academic Unit of Medical Genetics, University of Manchester, St Mary s Hospital, Manchester, UK
J Med Genet 44:225-32. 2007..identified in the causative retinoschisis gene (RS1) which encodes a 224 amino acid secretory retinal protein, retinoschisin. Retinoschisin octamerisation is implicated in cell-cell interactions and cell adhesion perhaps by interacting ..
- Truncation of retinoschisin protein associated with a novel splice site mutation in the RS1 geneBalázs Lesch
Department of Ophthalmology, Semmelweis University, Budapest, Hungary
Mol Vis 14:1549-58. 2008..of a Hungarian family with X-linked juvenile retinoschisis (XLRS) and to reveal a novel putative splice mutation leading to serious truncation of retinoschisin (RS1) protein. Our genetic results were compared to a mouse model of XLRS.
- Retinoschisin expression and localization in rodent and human pineal and consequences of mouse RS1 gene knockoutYuichiro Takada
National Institute on Deafness and Other Communication Disorders, National Institutes of Health, Bethesda, MD 20892, USA
Mol Vis 12:1108-16. 2006..Recent expressed tag sequence (EST) analysis showed that several gene mutations, including RS1, which cause retinal degeneration, are also expressed in the pineal gland...
- Positional cloning of the gene associated with X-linked juvenile retinoschisisC G Sauer
Institut fur Humangenetik, Universitat Wurzburg, Germany
Nat Genet 17:164-70. 1997..Mapping and expression analysis of expressed sequence tags have identified a novel transcript, designated XLRS1, within the centromeric RS locus that is exclusively expressed in retina...
- A novel mutation in the XLRS1 gene in a Korean family with X-linked retinoschisisHyoung Jun Koh
Department of Ophthalmology, Institute of Vision Research, Yonsei University College of Medicine, Seoul, Korea
Korean J Ophthalmol 20:62-4. 2006To report a novel missense mutation in the XLRS1 gene in a Korean family with X-linked retinoschisis.
- Four Japanese male patients with juvenile retinoschisis: only three have mutations in the RS1 geneTakaaki Hayashi
Department of Ophthalmology, Jikei University School of Medicine, Tokyo, Japan
Am J Ophthalmol 138:788-98. 2004To describe the clinical phenotypes of four unrelated Japanese male patients with juvenile retinoschisis and to investigate occurrences of mutations in the RS1 gene.
- Novel 473-bp deletion in XLRS1 gene in a Japanese family with X-linked juvenile retinoschisisKei Shinoda
Department of Ophthalmology, Keio University School of Medicine, 35 Shinanomachi, Shinjuku ku 160 8582, Tokyo, Japan
Graefes Arch Clin Exp Ophthalmol 242:561-5. 2004..To present the clinical features of two brothers with molecularly confirmed X-linked juvenile retinoschisis (xlRS) but with non-characteristic electrophysiological findings...
- Identification of four novel mutations of the XLRS1 gene in Japanese patients with X-linked juvenile retinoschisis. Mutation in brief no. 234. OnlineY Mashima
Department of Ophthalmology, Keio University School of Medicine, Tokyo, Japan
Hum Mutat 13:338. 1999The XLRS1 gene (HUGO-approved symbol, RS1) has been found to cause X-linked recessive retinoschisis (RS) which is characterized by splitting of the superficial layer of the retina...
- RS1, a discoidin domain-containing retinal cell adhesion protein associated with X-linked retinoschisis, exists as a novel disulfide-linked octamerWinco W H Wu
Department of Biochemistry and Molecular Biology, University of British Columbia, Vancouver, British Columbia, V6T 1Z3, Canada
J Biol Chem 280:10721-30. 2005RS1, also known as retinoschisin, is an extracellular protein that plays a crucial role in the cellular organization of the retina...
- Molecular genetic characteristics of X-linked retinoschisis in KoreansSo Yeon Kim
Department of Laboratory Medicine, Seoul National University Hospital, Seoul, Korea
Mol Vis 15:833-43. 2009..Many genetic studies had focused on the patients in Western countries. We characterized the mutational spectrum of the RS1 gene in Korean patients with XLRS, and aimed to provide genetic information of XLRS in an Asian population.
- Identification of novel mutations in the XLRS1 gene in Chinese patients with X-linked juvenile retinoschisisMeizhen Zeng
State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat Sen University, Guangzhou, China
Curr Eye Res 32:685-91. 2007..In this study we analyzed all six exons of the XLRS1 gene in four sporadic XLRS patients and in an affected family in China who were recently diagnosed...
- Clinical features of X linked juvenile retinoschisis in Chinese families associated with novel mutations in the RS1 geneXiaoxin Li
Department of Ophthalmology, People s Hospital, Peking University, Beijing, PR China
Mol Vis 13:804-12. 2007To describe the clinical phenotype of X linked juvenile retinoschisis (XLRS) in 12 Chinese families with 11 different mutations in the XLRS1 (RS1) gene.
- Correlation of genetic and clinical findings in Spanish patients with X-linked juvenile retinoschisisRosa Riveiro-Alvarez
Department of Genetics, Fundacion Jimenez Diaz, Madrid, Spain
Invest Ophthalmol Vis Sci 50:4342-50. 2009..This study was conducted to describe and further correlate specific genetic variation in Spanish patients with XLRS with clinical characteristics and additional ophthalmic complications...
- Three widespread founder mutations contribute to high incidence of X-linked juvenile retinoschisis in FinlandL Huopaniemi
Department of Medical Genetics, University of Helsinki, Finland
Eur J Hum Genet 7:368-76. 1999..The gene defective in retinoschisis, XLRS1, has recently been identified and characterised...
- Japanese juvenile retinoschisis is caused by mutations of the XLRS1 geneY Hotta
Department of Ophthalmology, Juntendo University School of Medicine, Tokyo, Japan
Hum Genet 103:142-4. 1998We investigated the XLRS1 gene in Japanese patients with retinoschisis (RS)...
- Three novel mutations in the X-linked juvenile retinoschisis (XLRS1) gene in 6 Japanese patients, 1 of whom had Turner's syndromeMasaki Sato
Department of Ophthalmology, University Hospital of Tsukuba, University of Tsukuba, Tsukuba, Ibaraki Ken, Japan
Ophthalmic Res 35:295-300. 2003We examined the XLRS1 gene for mutations in 6 Japanese patients with X-linked juvenile retinoschisis from a total of three families (5 males and 1 female), and from 3 obligate carrier females...
- Clinical and genetic findings in Hungarian patients with X-linked juvenile retinoschisisB Lesch
Department of Ophthalmology, Semmelweis University, Budapest, Hungary
Mol Vis 14:2321-32. 2008To determine clinical phenotypes, examine the age dependency of X-linked juvenile retinoschisis (XLRS), and identify mutations in the retinoschisis1 gene (RS1) in 13 Hungarian (Caucasian) families with this disease.
- Evidence for a new locus for X-linked retinitis pigmentosa (RP23)A J Hardcastle
Department of Molecular Genetics, Institute of Ophthalmology, University College London, United Kingdom
Invest Ophthalmol Vis Sci 41:2080-6. 2000..To investigate the level of heterogeneity for XLRP in the patient pool in the current study, extensive haplotype analysis, linkage analysis, and mutation screening were performed...
- Retinoschisin (RS1) interacts with negatively charged lipid bilayers in the presence of Ca2+: an atomic force microscopy studySvetlana Kotova
LBPS, National Institute of Biomedical Imaging and Bioengineering, National Institutes of Health, Bethesda, Maryland 20892, USA
Biochemistry 49:7023-32. 2010b>Retinoschisin (RS1) is a retina-specific secreted protein encoding a conserved discoidin domain sequence. As an adhesion molecule, RS1 preserves the retinal cell architecture and promotes visual signal transduction...
- Synaptic pathology in retinoschisis knockout (Rs1-/y) mouse retina and modification by rAAV-Rs1 gene deliveryYuichiro Takada
Section for Translational Research in Retinal and Macular Degeneration, National Institute on Deafness and Other Communication Disorders, National Institutes of Health, Bethesda, Maryland 20892, USA
Invest Ophthalmol Vis Sci 49:3677-86. 2008At an early age, the retinoschisin knockout (Rs1-KO) mouse retina has progressive photoreceptor degeneration with severe disruption of the outer plexiform layer (OPL) that decreases at older ages...
- [Molecular genetics of pigmentary retinopathies: identification of mutations in CHM, RDS, RHO, RPE65, USH2A and XLRS1 genes]C P Hamel
Laboratoire de Neurobiologie, INSERM U 254, 71, rue de Navacelles, 34090 Montpellier
J Fr Ophtalmol 23:985-95. 2000..To characterize genes and mutations causing these conditions...
- Preimplantation genetic diagnosis of X-linked retinoschisisBelén Lledó
Department of Molecular Biology, Infertility Centre, Instituto Bernabeu, Alicante 03016, Spain
Reprod Biomed Online 16:886-92. 2008..using multiple displacement amplification (MDA) for whole genome amplification and linked markers to the RS1 gene. The study evaluates the ability of MDA to amplify the whole genome directly from a single blastomere...
- X-linked retinoschisis in three females from the same family: a phenotype-genotype correlationFrancisco J Rodriguez
Fundacion Oftalmologica Nacional, Facultad de Medicina, Universidad del Rosario, Bogota, Colombia
Retina 25:69-74. 2005..To describe the clinical findings and outcome for three homozygous females affected with X-linked retinoschisis (XLRS) in a large Colombian family with 26 affected males...
- Reduced synaptic vesicle density and aberrant synaptic localization caused by a splice site mutation in the Rs1h geneBritt A Johnson
Department of Medical Genetics, University of Wisconsin Madison, Madison, Wisconsin 53706, USA
Vis Neurosci 23:887-98. 2006X-linked retinoschisis (XLRS) is a common form of inherited macular degeneration caused by mutations in the RS1 gene...
- Retinoschisin forms a multi-molecular complex with extracellular matrix and cytoplasmic proteins: interactions with beta2 laminin and alphaB-crystallinMarie France Steiner-Champliaud
Laboratoire de Physiopathologie Cellulaire et Moleculaire de la Retine, INSERM U 592, Hopital St Antoine, Paris, France
Mol Vis 12:892-901. 2006..The affected gene normally codes for retinoschisin (Rs1), a secreted protein containing a large discoidin homology domain...
- The mouse X-linked juvenile retinoschisis cDNA: expression in photoreceptorsS N Reid
Jules Stein Eye Institute, UCLA School of Medicine, Los Angeles, CA 90095, USA
Gene 227:257-66. 1999..and amino acid sequences, as well as chromosome mapping, we determined that this gene is the mouse ortholog (Xlrs1) of the human X-linked juvenile retinoschisis gene (XLRS1)...
- Molecular genetics of macular degenerationM A Musarella
Long Island College Hospital, Department of Ophthalmology, Brooklyn, NY 11231, USA
Doc Ophthalmol 102:165-77. 2001..The gene mutant in X-linked juvenile retinoschisis, XLRS1, is the first macular dystrophy gene to be isolated by positional cloning...
- Phenotypic expression of juvenile X-linked retinoschisis in Swedish families with different mutations in the XLRS1 geneL C Eksandh
Department of Ophthalmology, University Hospital, Lund, Sweden
Arch Ophthalmol 118:1098-104. 2000To describe the clinical phenotype of juvenile X-linked retinoschisis in patients with different mutations in the XLRS1 gene.
- Clinical characteristics of 14 japanese patients with X-linked juvenile retinoschisis associated with XLRS1 mutationK Shinoda
Department of Ophthalmology, Keio University School of Medicine, Shinjuku ku, Tokyo, Japan
Ophthalmic Genet 21:171-80. 2000To characterize the clinical features associated with XLRS1 gene mutations in Japanese patients with X-linked juvenile retinoschisis (xlRS), we evaluated the following data on 14 Japanese males from 13 unrelated families with XLRS1 ..
- Characterization and purification of the discoidin domain-containing protein retinoschisin and its interaction with galactoseFrank M Dyka
Department of Biochemistry and Molecular Biology, Centre for Macular Research, University of British Columbia, 2350 Health Sciences Mall, Vancouver, BC V6T 1Z3, Canada
Biochemistry 47:9098-106. 2008RS1, also known as retinoschisin, is an extracellular discoidin domain-containing protein that has been implicated in maintaining the cellular organization and synaptic structure of the vertebrate retina...
- CRX controls retinal expression of the X-linked juvenile retinoschisis (RS1) geneThomas Langmann
Institute of Human Genetics, University of Regensburg, Regensburg, Germany
Nucleic Acids Res 36:6523-34. 2008X-linked juvenile retinoschisis is a heritable condition of the retina in males caused by mutations in the RS1 gene. Still, the cellular function and retina-specific expression of RS1 are poorly understood...
- Molecular mechanisms leading to null-protein product from retinoschisin (RS1) signal-sequence mutants in X-linked retinoschisis (XLRS) diseaseCamasamudram Vijayasarathy
Section on Translational Research for Retinal and Macular Degeneration, National Institute on Deafness and Other Communication Disorders, National Institutes of Health NIH, Bethesda, Maryland 20892, USA
Hum Mutat 31:1251-60. 2010b>Retinoschisin (RS1) is a cell-surface adhesion molecule expressed by photoreceptor and bipolar cells of the retina...
- Juvenile X-linked retinoschisis with normal scotopic b-wave in the electroretinogram at an early stage of the diseaseLouise Eksandh
Department of Ophthalmology, University Hospital of Lund, Sweden
Ophthalmic Genet 26:111-7. 2005To report four cases of genetically verified juvenile X-linked retinoschisis (XLRS) with normal scotopic b-waves in full-field ERG, including one patient with a novel mutation (W50X) in the RS1 gene.
- Isolation and characterization of the murine X-linked juvenile retinoschisis (Rs1h) geneA E Gehrig
Institut fur Humangenetik, Biozentrum, Am Hubland, Universitat Wurzburg, 97074 Wurzburg, Germany
Mamm Genome 10:303-7. 1999X-linked juvenile retinoschisis (RS) is a vitreoretinal degeneration affecting only males. Recently, the RS1 gene underlying this common cause of early vision loss was identified and shown to encode a 224-amino acid precursor protein ..
- The effects of transient retinal detachment on cavity size and glial and neural remodeling in a mouse model of X-linked retinoschisisGabriel Luna
Neuroscience Research Institute, University of California Santa Barbara, Santa Barbara, CA 93106 5060, USA
Invest Ophthalmol Vis Sci 50:3977-84. 2009To determine the cellular consequences of retinal detachment in retinoschisin knockout (Rs1-KO) mice, a model for retinoschisin in humans.
- Genetic modification of the schisis phenotype in a mouse model of X-linked retinoschisisBritt A Johnson
Department of Medical Genetics, University of Wisconsin, Madison, Wisconsin 53706, USA
Genetics 178:1785-94. 2008X-linked retinoschisis (XLRS) is an inherited form of macular degeneration that is caused by mutations in the retinoschisin (RS1) gene...
- Identification of XLRS1 gene mutation (608C > T) in a Portuguese family with juvenile retinoschisisC Teixeira
Department of Ophthalmology, Hospital de S João Hospital, Porto, Portugal
Eur J Ophthalmol 15:638-40. 2005To characterize electroretinogram (ERG) and molecular genetic findings in a family with XLRS1 mutation. The authors present two cases of a Portuguese family with juvenile retinoschisis with a mutation in exon 6.
- Intravitreal delivery of AAV8 retinoschisin results in cell type-specific gene expression and retinal rescue in the Rs1-KO mouseT K Park
Section for Translational Research in Retinal and Macular Degeneration, National Institute on Deafness and Other Communication Disorders, National Institutes of Health, Bethesda, MD, USA
Gene Ther 16:916-26. 2009X-linked juvenile retinoschisis (XLRS) is a neurodevelopmental abnormality caused by retinoschisin gene mutations...
- Tyrosinase is the modifier of retinoschisis in miceBritt A Johnson
Department of Medical Genetics, University of Wisconsin, Madison, WI 53706, USA
Genetics 186:1337-44. 2010..This disease is caused by mutations in the retinoschisin (RS1) gene...
- On- and off-responses of the photopic electroretinograms in X-linked juvenile retinoschisisK Shinoda
Department of Ophthalmology, Keio University School of Medicine, Shinjuku ku, Tokyo, Japan
Am J Ophthalmol 131:489-94. 2001..To examine the physiologic condition of the middle retinal layer of patients with X-linked juvenile retinoschisis (xlRS) by studying the on- and off-responses of the photopic electroretinograms (ERGs)...
- Prolonged recovery of retinal structure/function after gene therapy in an Rs1h-deficient mouse model of x-linked juvenile retinoschisisSeok H Min
Department of Ophthalmology, University of Florida College of Medicine, Gainesville, 32610, USA
Mol Ther 12:644-51. 2005..mouse model of human RS, delivery of the human RS1 cDNA with an AAV vector restored expression of retinoschisin to both photoreceptors and the inner retina essentially identical to that seen in wild-type mice...
- An unusual X-linked retinoschisis phenotype and biochemical characterization of the W112C RS1 mutationAlessandro Iannaccone
Hamilton Eye Institute, Department of Ophthalmology, University of Tennessee Health Science Center, 930 Madison Avenue, Suite 731, Memphis, TN 38163, USA
Vision Res 46:3845-52. 2006..Although in vitro studies showed that the W112C mutant retinoschisin is present only in the cellular fraction and is not secreted, disease expression was remarkably mild, ..
- Genotypic analysis of X-linked retinoschisis in Western AustraliaTina Lamey
Department of Medical Technology and Physics, Sir Charles Gairdner Hospital, Hospital Avenue, Nedlands, WA 6009, Australia
Adv Exp Med Biol 664:283-91. 2010..By direct sequencing of the RS1 gene, three genetic variants were identified; 52+1G > T, 289T > G and 416delA...
- Severe juvenile retinoschisis associated with a 33-bps deletion in XLRS1 geneK Shinoda
Department of Ophthalmology, Keio University School of Medicine, Tokyo, Japan
Ophthalmic Genet 20:57-61. 1999..This patient with a severe form of retinoschisis was found to harbor the deletion of 33 base pairs, including the boundary region of exon 3 and intron 3 in the XLRS1 gene.
- Functional characteristics of patients with retinal dystrophy that manifest abnormal parafoveal annuli of high density fundus autofluorescence; a review and updateAnthony G Robson
Department of Electrophysiology, Moorfields Eye Hospital, 162 City Road, London EC1 2PD, UK
Doc Ophthalmol 116:79-89. 2008..To examine the presence and functional significance of annular fundus autofluorescence abnormalities in patients with different retinal dystrophies...
- RS1 element of Vibrio cholerae can propagate horizontally as a filamentous phage exploiting the morphogenesis genes of CTXphiShah M Faruque
Molecular Genetics Laboratory, International Centre for Diarrhoeal Disease Research, Bangladesh, Dhaka 1212, Bangladesh
Infect Immun 70:163-70. 2002..Integrated CTXPhi is often flanked by another genetic element known as RS1 which carries all open reading frames (ORFs) found in RS2 and an additional ORF designated rstC...
- Evolutionary genetic analysis of the emergence of epidemic Vibrio cholerae isolates on the basis of comparative nucleotide sequence analysis and multilocus virulence gene profilesYvonne A O'Shea
Department of Microbiology, University College Cork, National University of Ireland, Cork, Ireland
J Clin Microbiol 42:4657-71. 2004..Of the 12 virulence regions examined, only three regions, Vibrio seventh pandemic island 1 (VSP-I), VSP-II, and RS1, were absent from all classical V. cholerae isolates. Most V...
- Genomic analysis of the Mozambique strain of Vibrio cholerae O1 reveals the origin of El Tor strains carrying classical CTX prophageShah M Faruque
Molecular Genetics Laboratory, International Centre for Diarrhoeal Disease Research, Bangladesh, Dhaka 1212, Bangladesh
Proc Natl Acad Sci U S A 104:5151-6. 2007..strain shares most of its genes with the typical El Tor strain N16961 but did not carry the TLC gene cluster, and RS1 sequence, adjacent to the CTX prophage...
- Reversal of gene expression profile in the phenylketonuria mouse model after adeno-associated virus vector-mediated gene therapyHyun Jeong Oh
Department of Biomedical Sciences, National Institute of Health, Seoul 122 701, Republic of Korea
Mol Genet Metab 86:S124-32. 2005..an immunoglobulin alpha heavy chain constant region gene (Igh-2), an osteocalcin-related protein precursor (Bglap-rs1), and a membrane-spanning 4 domain, subfamily A, member 3 (Ms4a3)...
- AVPR1a and SLC6A4 gene polymorphisms are associated with creative dance performanceRachel Bachner-Melman
Department of Psychology, Mount Scopus, Hebrew University, Jerusalem, Israel
PLoS Genet 1:e42. 2005..region HTTLPR and intron 2 VNTR) and the arginine vasopressin receptor 1a (AVPR1a: promoter microsatellites RS1 and RS3)...
- Individual differences in allocation of funds in the dictator game associated with length of the arginine vasopressin 1a receptor RS3 promoter region and correlation between RS3 length and hippocampal mRNAA Knafo
Psychology Department, Hebrew University, Jerusalem, Israel
Genes Brain Behav 7:266-75. 2008..All subjects and their parents were genotyped for AVPR1a RS1 and RS3 promoter-region repeat polymorphisms. Parents did not participate in online game playing...
- The mouse gene encoding the GM2 activator protein (Gm2a): cDNA sequence, expression, and chromosome mappingS Yamanaka
Section on Biochemical Genetics, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland 20892
Genomics 24:601-4. 1994..The Gm2a gene was mapped to a region on mouse chromosome (Chr) 11 that is homologous with a segment of human chromosome 5 containing the orthologous human gene. In addition, a Gm2a-related sequence (Gm2a-rs1) was mapped to mouse Chr 5.
- Repeat linear accelerator radiosurgery for cerebral arteriovenous malformationsMichel Schlienger
Department of Radiotherapy, Radiophysics Tenon Hospital, Paris, France
Int J Radiat Oncol Biol Phys 56:529-36. 2003To evaluate repeat radiosurgery (RS2) for cerebral arteriovenous malformations (AVMs) after failure of initial radiosurgery (RS1).
- Pseudomonas oleovorans subsp. lubricantis subsp. nov., and reclassification of Pseudomonas pseudoalcaligenes ATCC 17440T as later synonym of Pseudomonas oleovorans ATCC 8062 TRatul Saha
Biological Sciences, Michigan Technological University, Houghton, MI, USA
Curr Microbiol 60:294-300. 2010Isolate RS1(T) isolated from used metalworking fluid was found to be a Gram-negative, motile, and non-spore forming rod. Based on phylogenetic analyses with 16S rRNA, isolate RS1(T) was placed into the mendocina sublineage of Pseudomonas...
- Association between the arginine vasopressin 1a receptor (AVPR1a) gene and autism in a family-based study: mediation by socialization skillsN Yirmiya
Department of Psychology, Hebrew University, Jerusalem, Israel
Mol Psychiatry 11:488-94. 2006We examined three microsatellites in the arginine vasopressin 1a receptor gene (AVPR1a), two in the promoter region (RS1 and RS3) and an intronic microsatellite (AVR), for association with autism as well as scores on the Vineland ..
- Metabolic roles of a Rhodobacter sphaeroides member of the sigma32 familyR K Karls
Department of Bacteriology, University of Wisconsin Madison, 53706, USA
J Bacteriol 180:10-9. 1998..sphaeroides deltaRpoH mutant is not generally defective in phage morphogenesis, since it plates the lytic virus RS1, as well as its wild-type parent. In characterizing the response of R...
- Induction of effective immunity to Moloney murine sarcoma virus using monoclonal anti-idiotypic antibody as immunogenT J Powell
Birmingham Veterans Administration Medical Center, Department of Surgery, AL
J Immunol 142:1318-24. 1989We have isolated an anti-idiotypic mAb (RS1.1.3), which recognizes an idiotope present on several IgM mAb specific for Moloney murine leukemia virus (M-MuLV)-determined cell surface Ag. The binding of RS1.1...
- Genetic variation in S-nitrosoglutathione reductase (GSNOR) and childhood asthmaHao Wu
Laboratory of Respiratory Biology, Division of Intramural Research, National Institute of Environmental Health Sciences, National Institutes of Health, Department of Health and Human Services, Research Triangle Park, NC 27709, USA
J Allergy Clin Immunol 120:322-8. 2007..GSNOR knockout mice have increased lung S-nitrosothiol levels and are therefore protected from airway hyperresponsiveness after methacholine or allergen challenge...
- Roles of COMM-domain-containing 1 in stability and recruitment of the copper-transporting ATPase in a mouse hepatoma cell lineTakamitsu Miyayama
Laboratory of Chemical Toxicology and Environmental Health, Showa Pharmaceutical University, Machida, Tokyo 194 8543, Japan
Biochem J 429:53-61. 2010A novel function of COMMD1 {COMM [copper metabolism MURR1 (mouse U2af1-rs1 region 1)]-domain-containing 1}, a protein relevant to canine copper toxicosis, was examined in the mouse hepatoma cell line Hepa 1-6 with multi-disciplinary ..
- Vibrio cholerae O1 clinical strains isolated in 1992 in Kolkata with progenitor traits of the 2004 Mozambique variantSouvik Chatterjee
National Institute of Cholera and Enteric Diseases, Kolkata, India
J Med Microbiol 58:239-47. 2009..With the features of classical CTX prophage, localization in the small chromosome, and an absence of RS1 and pTLC, both Mozambique and Kolkata strains appeared to be identical...
- Classical RS1 and environmental RS1 elements in Vibrio cholerae O1 El Tor strains harbouring a tandem repeat of CTX prophage: revisiting Mozambique in 2005Seon Young Choi
International Vaccine Institute, Seoul, Republic of Korea
J Med Microbiol 59:302-8. 2010..New type RS1 elements RS1(cla) and RS1(env), and a CTX(env) with rstR(env) and the classical ctxB were identified on the large ..
- RS1 (RSC1A1) regulates the exocytotic pathway of Na+-D-glucose cotransporter SGLT1Maike Veyhl
Institut für Anatomie und Zellbiologie der Universität Würzburg, Koellikerstr 6, 97070 Wurzburg, Germany
Am J Physiol Renal Physiol 291:F1213-23. 2006The product of gene RSC1A1, named RS1, participates in transcriptional and posttranscriptional regulation of the sodium-d-glucose cotransporter SGLT1...
- Recognition Preference of Rhodamine-Thiospirolactams for Mercury(II) in Aqueous SolutionWei Huang
Coordination Chemistry Institute, State Key Laboratory of Coordination Chemistry, Nanjing University, Nanjing 210093, P R China
Inorg Chem 48:5061-72. 2009..the design, syntheses, photophysical properties and Hg(2+)-binding of the red-emitting rhodamine derivatives RS1, RS2, and RS3 with different coordination ability and different spatial effects that derived from rhodamine ..
- The shuffling function of resolvasesG Kholodii
Institute of Molecular Genetics, Russian Academy of Sciences, 123182, Moscow, Russia
Gene 269:121-30. 2001..the res site of RP4 located in the par locus, the res site of transposon gammadelta or Tn1721, the incomplete site RS1 consisting only of the (crossover) subsite resI also found in pKLH2/204/205 and others were used...
- Transporter regulator RS1 (RSC1A1) coats the trans-Golgi network and migrates into the nucleusMatthias Kroiss
Institut für Anatomie und Zellbiologie der Universität Würzburg, Koellikerstr 6 97070 Würzburg, Germany
Am J Physiol Renal Physiol 291:F1201-12. 2006The product of gene RSC1A1, named RS1, is involved in transcriptional and posttranscriptional regulation of sodium-d-glucose cotransporter SGLT1, and removal of RS1 in mice led to an increase of SGLT1 expression in small intestine and to ..
- Cloning of a membrane-associated protein which modifies activity and properties of the Na(+)-D-glucose cotransporterM Veyhl
Max Planck Institut fur Biophysik, Frankfurt am Main, Germany
J Biol Chem 268:25041-53. 1993..A., Coady, M.J., Ikeda, T.S., and Wright, E.M. (1987) Nature 330, 379-381). A cDNA (RS1) was obtained which codes for a hydrophilic M(r) 66,832 polypeptide and contains a predicted hydrophobic alpha-..
- Comparative study of lipid composition and proliferative activity of rat cholangiocarcinoma RS1 and sarcoma M1 depending on the transplantation organV A Kobliakov
Institute of Carcinogenesis, Blokhin Cancer Research Center, Russian Academy of Medical Sciences, Moscow, 115478, Russia
Biochemistry (Mosc) 67:1258-61. 2002..The proliferative activity and lipid composition (phospholipids, gangliosides) were studied in rat cholangiocarcinoma RS1 and sarcoma M1 transplanted subcutaneously or intrahepatically...
- Purification and characterization of an inverting stereo- and enantioselective sec-alkylsulfatase from the gram-positive bacterium Rhodococcus ruber DSM 44541Mateja Pogorevc
Department of Chemistry, Organic and Bioorganic Chemistry, University of Graz, Heinrichstrasse 28, A 8010 Graz, Austria
Appl Environ Microbiol 69:2810-5. 2003..From the crude cell-free lysate, two proteins responsible for sulfate ester hydrolysis (designated RS1 and RS2) were separated from each other based on their different hydrophobicities and were subjected to further ..
- The CSC connects three major axonemal complexes involved in dynein regulationThomas Heuser
Biology Department, Rosenstiel Center, Brandeis University, Waltham, MA 02454, USA
Mol Biol Cell 23:3143-55. 2012..Chlamydomonas flagella have two full-length radial spokes, RS1 and RS2, and a shorter RS3 homologue, the RS3 stand-in (RS3S)...
- New triterpenoid saponins from fruits specimens of Panax japonicus collected in Kumamoto and Miyazaki prefectures (1)Kouichi Yoshizaki
Graduate School of Pharmaceutical Sciences, Kumamoto University, Kumamoto, Japan
Chem Pharm Bull (Tokyo) 60:354-62. 2012..9), ginsenoside Rc (10), chikusetsusaponin VI (11), ginsenoside Re (12), ginsenoside Rg1 (13), pseudo-ginsenoside RS1 (14), notoginsenoside R1 (15), chikusetsusaponin L5) (17), chikusetsusaponin L10 (18), chikusetsusaponin IVa (19), ..
- X-linked juvenile retinoschisis: clinical diagnosis, genetic analysis, and molecular mechanismsRobert S Molday
Department of Biochemistry and Molecular Biology, Centre of Macular Research, University of British Columbia, 2350 Health Sciences Mall, Vancouver, B C V6T 1Z3, Canada
Prog Retin Eye Res 31:195-212. 2012..The RS1 gene (MIM 300839) associated with the disease encodes retinoschisin, a 224 amino acid protein containing a discoidin domain as the major structural unit, an N-terminal cleavable ..
- Tissue regeneration in vivo within recombinant spidroin 1 scaffoldsMikhail M Moisenovich
Department of Bioengineering, Lomonosov Moscow State University, Moscow, Russian Federation
Biomaterials 33:3887-98. 2012..different silk proteins, fibroin of Bombyx mori and a recombinant analog of Nephila clavipes spidroin 1 known as rS1/9, and their biocompatibility and degradation behavior in vitro and in vivo...
- Multilocus variable-number tandem repeat analysis of Vibrio cholerae O1 El Tor strains harbouring classical toxin BSeon Young Choi
International Vaccine Institute, Seoul, Republic of Korea
J Med Microbiol 59:763-9. 2010..into two MLVA groups (group I: Mozambique/Bangladesh group; group III: Vietnam group), and altered strains with the RS1-CTX prophage containing the El Tor type rstR and classical ctxB on the large chromosome were placed in two MLVA ..
- Chromosomal assignment of three novel mouse genes expressed in testicular cellsL Lemaire
Institut fur Genetik, Heinrich Heine Universitat, Dusseldorf, Federal Republic of Germany
Genomics 21:409-14. 1994..ii) TNZ1 is located in the proximal region of chromosome 11; and (iii) TAZ4 is located at band D in the distal portion of chromosome 11, near the Hlr1 locus, with a related sequence, TAZ4-rs1, in the proximal part of chromosome 1.
- Wild-type and missense mutants of retinoschisin co-assemble resulting in either intracellular retention or incorrect assembly of the functionally active octamerLindsay J Gleghorn
Faculty of Life Sciences, University of Manchester, Simon Building, Oxford Road, Manchester M13 9PL, UK
Biochem J 425:275-83. 2010The X-linked disease retinoschisis is caused by mutations in the RS1 gene encoding retinoschisin, most commonly missense mutations leading to a lack of secretion of functional protein...
- Sealing ability of a new carrier-based obturating materialL Testarelli
Department of Dental Sciences, La Sapienza University, Rome, Italy
Minerva Stomatol 58:217-24. 2009....
- Egr-1 activation of rat adrenal phenylethanolamine N-methyltransferase geneS N Ebert
Department of Psychiatry and Behavioral Sciences, Nancy Pritzker Laboratory of Developmental and Molecular Neurobiology, Standford University School of Medicine, California 94305 5485
J Biol Chem 269:20885-98. 1994..promoter-luciferase construct and an Egr-1 expression construct are cotransfected into transformed PC12 cells (RS1). Egr-1 also stimulates endogenous PNMT mRNA expression in the RS1 cells...
- Transcript- and tissue-specific imprinting of a tumour suppressor geneReiner Schulz
Department of Medical and Molecular Genetics, King s College London, London SE1 9RT, UK
Hum Mol Genet 18:118-27. 2009..of Nnat in brain, as has been suggested previously for the similarly organized and imprinted murine Commd1/U2af1-rs1 locus...
- Reproductive and epigenetic outcomes associated with aging mouse oocytesFlavia L Lopes
Department of Human Genetics, McGill University and Montreal Children s Hospital of the McGill University Health Centre Research Institute, Montreal, Quebec, Canada H3H 1P3
Hum Mol Genet 18:2032-44. 2009..changes in methylation of the differentially methylated regions of imprinted genes Snrpn, Kcnq1ot1, U2af1-rs1, Peg1, Igf2r and H19...
- Molecular modeling of retinoschisin with functional analysis of pathogenic mutations from human X-linked retinoschisisY V Sergeev
Ophthalmic Genetics and Visual Function Branch, National Eye Institute, National Institutes of Health, Bethesda, MD 20892, USA
Hum Mol Genet 19:1302-13. 2010Gene mutations that encode retinoschisin (RS1) cause X-linked retinoschisis (XLRS), a form of juvenile macular and retinal degeneration that affects males...
- Characterization of shark complement factor I gene(s): genomic analysis of a novel shark-specific sequenceDong Ho Shin
Department of Biological Sciences, Florida International University, Miami, FL 33199, USA
Mol Immunol 46:2299-308. 2009..of each SSR has identified within the region two novel short sequences (SS1 and SS2) and three repeat sequences (RS1-3)...
- Nucleotide sequence, expression, and chromosomal mapping of Mrp and mapping of five related sequencesD F Lobach
Howard Hughes Medical Institute Laboratories, Section of Diabetes and Metabolism, Division of Endocrinology, Metabolism, and Nutrition, Department of Medicine
Genomics 17:194-204. 1993..Five related loci were labeled Mrp-rs1 through Mrp-rs5 (for Mrp-related sequences) and were mapped to mouse chromosomes 10, 17, 15, 13, and X, ..
Research Grants7
- Genetic Modifier of the Retinoschisis GeneAkihiro Ikeda; Fiscal Year: 2010..X-linked retinoschisis (XLRS) is a common inherited macular degenerative disease caused by mutations in the RS1 gene...
- MOLECULAR BIOLOGY AND VIRULENCE OF CTX PHAGEMatthew Waldor; Fiscal Year: 2007..form of CTXphi is found as part of tandem arrays of prophage DNA interspersed with the related genetic element RS1. RS1 encodes a protein, RstC, that can counter RstR repression and lead to markedly enhanced expression of CTX ..
- DEVELOPMENTAL BIOLOGY AND GENETICS OF THE MAIZE LEAFMichael Freeling; Fiscal Year: 2001..Rice will be used as a control genome. Aim number 2. We will determine if RS2 directly binds the rs1 gene. We will use a yeast one-hybrid screen and protein-DNA slot-blots...
- Genomic Sequence of an Otitis Media Isolate of NTHiRobert Munson; Fiscal Year: 2003..We propose to close and annotate the genome of nontypeable H. influenzae strain 86-028. ..
- OCULAR MELANOMAJudy Kim; Fiscal Year: 2003..Standardized clinical and data collection procedures will be employed, and standardized forms will be used in all centers. Central training and certification of all study staff will be required. ..
- Pasteurellaceae 2005Robert Munson; Fiscal Year: 2005..These 2 activities will assure that all of our conference goals are met. ..
- Protein Glycosylatin in Haemophilus ducreyiRobert Munson; Fiscal Year: 2007..ducreyi infection. [unreadable] [unreadable] [unreadable]..


text:
TEACH is supporting the Health Professions Educator Series 2017 and all Jefferson College of Health Sciences faculty are invited to attend all of the presentations.
Explore our Programs
News & Events
Feb. 28
Join the Jefferson College of Health Sciences Student Nurses Association (SNA) for a Bake Sale on Tuesday, February 28, from 8 a.m. to 1 p.m. in the 5th floor common area.
Feb. 28
Harrison Museum of African American Culture Open House & Lecture Series Presents: Guest Speaker Dr. Nathaniel L. Bishop
You are cordially invited to an Open House & Lecture Series event at the Harrison Museum of African American Culture, in collaboration with Hollins University, Roanoke College, Virginia Western
Feb. 28
Learn more about the NEW post-professional Doctor of Occupational Therapy Program at Jefferson College!


text:
Finishing Your Year 2016 Strong
By Jacklyn | August 22, 2016
Every year many people start with huge goals and dreams. Now, we are left with less-than 5 months to end 2016. Have you reviewed your goals? How are they doing?
If due to whatever reasons, your goals seems still far fetch, I strongly encourage you to go back to the basics… I find the 3 main necessary steps of goal setting by Peng Joon is very helpful and I've put his article for your reading. Wishing you success!
Effective goal setting comes in 3 main steps.
When it comes to planning your year, the most important thing is for you to have clarity.
You need to know what you want to begin with.
So the first step is to think about, and be clear on what you want to achieve this year.
Now most people stop here. They list down what they want and that's it. That's like putting an image of a sports car on your desktop wallpaper. Nothing happens.
Many times, people tell me: "Peng Joon, I want to make a million dollars this year."
Well, that's a great goal.
But the next step, after knowing what you want, is knowing why you want it.
What I always tell people is that once you know what you want, you need to have clarity on your "why".
So you want to make a million dollars…. the question now is why?
I list down about 10 things that I want to accomplish during the year – but instead of thinking about accomplishing them, I think about "why". This is something you should be doing, too.
Because if you can figure out the "why", then you can figure out the "how".
These are the steps. The mechanics. It needs to be specific and actionable.
Ineffective: I will go to the gym 3 times a week.
Effective: I will complete the p90X fitness program and complete all 90 days from start to end. I will limit my carbs intake by one bowl of rice a day.
So as a quick recap:
To be able to plan things out and make 2016 your best year ever, you need to:
1. Know WHAT you want to do
2. Know WHY you want to do it
3. List HOW are you going to do it
If you can plan these three things out next to each other, then you'll have a compelling reason to take action.
So, I hope this post has helped you in terms of planning to finish your year strong, and will enable you to really have the best year ever!
As always, if you found value in this post, please feel free to leave a comment below and let me know.
May 2016 be an amazing and incredible year filled with happiness, love, peace and everything else that you could wish for
Topics: Affirmations, Goals Setting, Positive Attitude, Wealth Creation | No Comments »
How Many Singapore Merlion Statues?
By Jacklyn | August 16, 2016
Have you ever wonder how many Merlion Statues are there in Singapore?
There are 7 of these half-lion, half-fish mythical creatures in Singapore. The 2 most famous ones are situated at the Merlion Park, next to One Fullerton.
The 2+5 such Merlion statues are at:
– Merlion Park (2 of them)
– Sentosa
– outside Singapore Tourism Board's office at Tourism Court
– Faber Point at Mount Faber
– Ang Mo Kio Ave 1 (2 pink-granite ones flanking the public carpark entrance along AMK Ave 1)
I've just returned from USA and realised that I know too little about my own country, Singapore!
Now having fun learning about this tiny island, my home, Singapore :)
Topics: General, Gratitude, Personal Life, Singapore | No Comments »
A Good Life Contains These 6 Essentials – Jim Rohn
By Jacklyn | October 27, 2014
The values that make up the foundation of a life well lived—and, no surprise, money isn't one of them.
The ultimate expression of life is not a paycheck. The ultimate expression of life is not a Mercedes. The ultimate expression of life is not a million dollars or a bank account or a home. The ultimate expression of life is living a good life.
Here's what we must ask constantly, "What, for me, would be a good life?" And you have to keep going over and over the list—a list including areas such as spirituality, economics, health, relationships and recreation.
So, what would constitute a good life? Jim Rohn has a short list:
1. Productivity
You won't be happy if you don't produce. The game of life is not rest. Yes, we must rest, but only long enough to gather strength to get back to productivity.
What's the reason for the seasons and the seeds, the soil and the sunshine, the rain and the miracle of life? It's to see what you can do with it—to try your hand to see what you can do.
2. Good friends Read the rest of this entry »
Topics: Affirmations, Friends, Gratitude, Inspiration, Motivation, Personal Development, Positive Attitude, Quotes, Self Esteem | 1 Comment »
Tiny Changes Mean Huge Results – Tony Robbins
By Jacklyn | October 26, 2014
"When it seems impossible, when it seems like nothing is going to work, you are usually a few millimeters away from making it happen." – Anthony Robbins
8:17 mins
… our physical physiology really do change our states, start putting on the empowering ones!
Related Posts:
Tony Robbins Featured in Success Magazine
Anthony Robbins – Create the Energy, Vitality and Health You Deserve!
Anthony Robbins – The Drive Behind Motivation
Anthony Robbins – The Power Of Belief
Topics: Anthony Robbins, Inspiration, Leadership, Motivation, NLP, Personal Development, Video | No Comments »
A Journey of Forgiveness
By Jacklyn | June 15, 2014
"To forgive is to set a prisoner free and discover that the prisoner was you." ~ Lewis B. Smedes
One of the secrets to happiness, peace of mind and good health is being able to free our minds of any anger, hatred or resentment towards others. While it is only human to feel angry and resentment towards those who have wronged you, it takes a true winner to be able to understand and forgive.
Recently, I have my fair share of people who have intimidated, humiliated, betrayed and wronged me. I was hurt and it took me a month's journey to face the world again..
I would like to share a talk by Ellen Rutledge whose son was brutally murdered but chose to forgive her son's killers… If she can learn to forgive the unforgivable, we can certainly learn to forgive the petty arguments or misunderstandings we have with our friends, family and colleagues. Ellen was one of the inspirational speakers at TEDx Ironwood, standing onstage along with prisoners, performers, educators and administrators to tell her story of forgiveness. Ellen's son was tragically murdered in 2008. She expanded on the power of forgiveness, and how it can bring freedom for both all parties. She now works at Ironwood State Prison, where their focus upon education and rehabilitation fits perfectly with Ellen's own philosophy.
A journey of forgiveness: Ellen Rutledge (6:24 mins)
Related Post:
Forgiveness – http://jacklynker.com/forgiveness/
Topics: Inspiration, Motivation, Personal Development, Video | No Comments »
Blood Test with Ionized Water
By Jacklyn | December 27, 2013
1:19 mins
To learn more about ionised water, especially the health effect of Kangen ionised water, visit www.jkangen.com
Topics: Health Tips, Hydration, Kangen Water, News, Recommendations, Video | No Comments »
Kangen Water used in Japan Hospitals
By Jacklyn | August 19, 2013
6:16 mins
Related posts:
Celebrities Drinking Kangen Water
What is your Source of Hydration?
Topics: Health Tips, Healthy Lifestyle, Hydration, Inspiration, Kangen Water, Personal Development, Recommendations, Video | No Comments »


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Back in 2006 I was fortunate enough to dig Ford's Supavan out of hibernation and drive it on an airstrip for a Max Power magazine shoot. The airstrip was active, so we had to wait for radio clearance between aircraft landings to run the old girl. The space framed scaled down Transit body was fitted with a mid-mounted supercharged V6 Cosworth engine (not F1 but totally unsilenced) and sequential gearbox. Rear wheel drive, obviously. This is what it sounds like....
DRIFT BUS na Torze "Poznań"
Driftujący Transit podczas finałowej rundy Driftingowych Mistrzostw Polski na Torze "Poznań"
Mitsubishi L300 VR4 Turbo Dragracing,Wanganui 17.4.11
My L300 van racing at the Wanganui Road Rodders 25th Anniversay Drags April 2011.


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About a hundred years before, at Jonah's preaching, the Ninevites repented, and were spared, yet, soon after, they became worse than ever. Nineveh knows not that God who contends with her, but is told what a God he is. It is good for all to mix faith with what is here said concerning Him, which speaks great terror to the wicked, and comfort to believers. Let each take his portion from it: let sinners read it and tremble; and let saints read it and triumph. The anger of the Lord is
contrasted with his goodness to his people. Perhaps they are obscure and little regarded in the world, but the Lord knows them. The Scripture character of Jehovah agrees not with the views of proud reasoners. The God and Father of our Lord Jesus Christ is slow to wrath and ready to forgive, but he will by no means acquit the wicked; and there is tribulation and anguish for every soul that doeth evil: but who duly regards the power of his wrath? (Na
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Seattle to Victoria Overnight with The Butchart Gardens
Starting From 2 Days / 1 Night
Journey from downtown Seattle on the Clipper and experience the famous Butchart Gardens on your overnight Victoria, BC vacation. Simply select the dates and times you want to travel, choose from a variety of excellent hotel options at a best price guarantee and relax on the less than three hour cruise to Victoria. Upon your arrival, board a motor coach from the Victoria terminal for a brief city tour before exploring the garden's 55-acres of brilliantly colored flowers!
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February 1-November 30, 2017
2 days / 1 night minimum
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Butchart Gardens and City Highlights Tour
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- 1 night Victoria hotel
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- Butchart Gardens admission
- All applicable taxes
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Passport, Passport Card or EDL required when crossing an international border
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Skip to comments.The First Time I Heard of Barack (with additional info)
Posted on 09/20/2009 1:17:34 AM PDT by BP2
Has anyone heard of this before? I did a search but came up negative.
Very interesting and if you list to the tape the man sounds very genuine.
Heres his written confession which happened to a physicist when he was in Russia:
The leader of the Communist Party USA may not be the only one doing Communist cartwheels. Brace yourself for what Im about to say next. Last fall, prior to the presidential election, a friend of mine, Dr. Wiley Drake, former second vice president for the Southern Baptist Convention, sent me an e-mail on which I didnt report. It just seemed too extreme. It was from a software developer
he met named Tom Fife who told of how he first heard of the name Barack.
I cant prove whether its true or not, but in light of all that is happening, it just doesnt seem that far-fetched anymore. All I know is that Tom Fife is a real guy not some e-mail scam. Ive talked to him. He was a government contractor with an active security clearance who took notes on his trips for debriefings with the Defense Intelligence Agency within the Department of Defense. This is what he wrote down after it happened in 1992, before anyone ever heard the name Barack:
The first time I heard of Barack
During the period of roughly February 1992 to mid-1994, I was making frequent trips to Moscow, Russia, in the process of starting a software development joint-venture company with some people from the Russian scientific community. One of the men in charge on the Russian side was named V. M.; he had a wife named T.M.
V. was a level-headed scientist, while his wife was rather deeply committed to the losing Communist cause a cause she obviously was not abandoning.
One evening, during a trip early in 1992, the American half of our venture were invited to V. & T.s Moscow flat as we were about to return to the States. The party went well and we had the normal dinner discussions.
As the evening wore on, T. developed a decidedly rough anti-American edge one her husband tried to quietly rein in.
The bottom line of the tirade she started against the United States went something like this:
You Americans always like to think that you have the perfect government and your people are always so perfect. Well then, why havent you had a woman president by now? You had a chance to vote for a woman vice president and you didnt do it.
The general response went something along the lines that you dont vote for someone just because of their sex. Besides, you dont vote for vice president, but the president and vice president as a ticket.
Well, I think you are going to be surprised when you get a black president very soon.
The consensus we expressed was that we didnt think there was anything innately barring that. The right person at the right time and sure, America would try to vote for the right person, be he or she, black or not.
What if I told you that you will have a black president very soon and he will be a Communist?
The out-of-the-blue remark was met by our stares. She continued, Well, you will; and he will be a Communist.
It was then that the husband unsuccessfully tried to change the subject; but she was on a roll and would have nothing of it. One of us asked, It sounds like you know something we dont know.
Yes, it is true. This is not some idle talk. He is already born, and he is educated and being groomed to be president right now. You will be impressed to know that he has gone to the best schools of presidents. He is what you call Ivy League. You dont believe me, but he is real and I even know his name. His name is Barack. His mother is white and American and his father is black from Africa. Thats right, a chocolate baby! And hes going to be your president.
She became more and more smug as she presented her stream of detailed knowledge and predictions so matter-of-factly as though all were foregone conclusions. Its all been thought out. His father is not an American black, so he wont have that social slave stigma. He is intelligent and he is half white and has been raised from the cradle to be an atheist and a Communist. Hes gone to the finest schools. He is being guided every step of the way and he will be irresistible to America.
We sat there not knowing what to say. She was obviously very happy that the Communists were doing this and that it would somehow be a thumbing of their collective noses at America: They would give us a black president and hed be a Communist to boot. She made it quite obvious that she thought that this was going to breathe new life into world Communism. From this and other conversations with her, she always asserted that Communism was far from dead.
She was full of little details about him that she was eager to relate. I thought that maybe she was trying to show off that this truly was a real person and not just hot air.
She rattled off a complete litany. He was from Hawaii. He went to school in California. He lived in Chicago. He was soon to be elected to the Legislature. Have no doubt: he is one of us, a Soviet.
At one point, she related some sort of San Francisco connection, but I didnt understand what the point was and dont recall much about that. I was just left with the notion that she considered the city to be some sort of a center for their activity here.
Since I had dabbled in languages, I knew a smattering of Arabic. I made a comment: If I remember correctly, Barack comes from the Arabic word for Blessing. That seems to be an odd name for an American. She replied quickly, Yes. It is African, she insisted, and he will be a blessing for world Communism. We will regain our strength and become the number one power in the world.
She continued with something to the effect that America was at the same time the great hope and the great obstacle for Communism. America would have to be converted to Communism, and Barack was going to pave the way.
So, what does this conversation from 1992 prove?
Well, its definitely anecdotal. It doesnt prove that Obama has had Soviet Communist training nor that he was groomed to be the first black American president, but it does show one thing that I think is very important. It shows that Soviet Russian Communists knew of Barack from a very early date. It also shows that they truly believed among themselves that he was raised and groomed Communist to pave the way for their future. This report on Barack came personally to me from one of them long before America knew he existed.
Although I had never before heard of him, at the time of this conversation Obama was 30-plus years old and was obviously tested enough that he was their anticipated rising star.
There have been attempts to discredit Fife with made up details, but the original version of Fifes story is posted online. Fife can be reached at: email@example.com.
Whether you believe this story or not, believe what the Communist Party USA has to say. Spending our way to the largest government in American history wont stimulate anything
other than the agenda of the Communist Party: taking over the private sector and capping peoples salaries. And thats just for starters. Call your senators at 202-224-3121 right now to stop this massive government takeover masquerading as a stimulus spending bill. Forget the hype: The world isnt going to end if this bill isnt passed, but democracy may end if it does.
Heres the audio:
Listening to the tape the man sounds authentic.
BTW, I have heard this account before.
I feel like we're in the Twilight Zone.
FARC logistics chief extradited to U.S.
Students of revisionist history will remember that Bill Clinton disappeared from Oxford University in England for a while in 1970 and surfaced in Moscow (courtesy of the CIA) purportedly to be trained in communism. When the accompanying story first appeared, we could not locate its source for confirmation and cast it off as a probable Internet fairy tale.
But we have since interviewed Tom Fife, blended the information with the many accusations of high-profile politicos (such as former UN Ambassador Alan Keyes) and witnessed the communistic behavior of the White House occupant, and we have no of doubt the authenticity of this amazing piece. Ed.
(Issue # 12, March 23, 2009)
FP: So tell us how the Soviet Union trained some of our Islamist enemies.
Rasmussen: It became clear to me that the entrance into the Soviet system for practically all foreign students was the Lumumba University. (Click here and also Click here) After one or two years of language training and "political training" here they were then distributed to other educational institutions according to their capabilities and desires.
Those who were talented agitators stayed back at the Lumumba University. Those who were mere thugs with severe personality disorders were sent to Romania and Bulgaria to learn guerrilla warfare. Bulgaria was the playground for large scale guerrilla operations including the use of mortars and anti tank weapons, while Romania had many centers for city guerrilla warfare.
The smarter ones were sent to other places such as Czechoslovakia or Eastern Germany. In Czechoslovakia they were given an education as chemical engineers at the so-called "Semtex University". (Click here and Click here) The education was genuine and serious, but what really made my hairs stand on one end was the immense overweight of practical training in the preparation and use of explosives. It was taught to the Iranian students even down to the minutest details that these skills were deemed necessary if their "revolutionary aims" were to succeed.
The PLO/Fatah movement remains true to its communist roots today, with Moscow-trained Mahmoud Abbas serving as chairman of the PLO. Abbas studied for a doctorate from Patrice Lumumba University in Moscow, finishing in 1982. KGB defector Yuri Bezmenov explained back in 1984 that Patrice Lumumba University was under the direct control of the KGB and [the] Central Committee, where future leaders of the so-called National Liberation Movements are being educated and selected carefully .
They were dispatched back to their countries to be leaders of the so-called National Liberation Movements, or, to be translated into normal human language, leaders of international terrorist groups. Abbas then defended his thesis at the Oriental Studies of the Soviet Academy of Sciences, which was then headed by former KGB General Yevgeny Primakov.
Raila Odinga educated in East Germany. Named his son Fidel. Obama helped Raila's Islamist murder/rape drive for power.
Campaigned for it; counseled it; financed it.
Obama is behaving in the precise manner we would predict were he a product of KGB Active Measures.
He has just made Papa Putin proud by renouncing our missile defense which so irritated the post-Soviet Commies in gangsta drag.
Barack Apparatchik Obamanov.
They wouldn't use his picture if this was an intelligence message.
Back in the day, newspaper stories were used to get messages out.
Today Kenya is run by a ruling coalition of the aging and ill President Mwai Kabaki, heir to the Kikuyu dominance of the earliest Kenyatta years, and the prison-schooled son of the early Luo leader, Oginga Odinga, Moscow's Patrice Lumumba University-trained Prime Minister Raila Odinga...
They can't control him. Look at the damage he is doing.
Maybe their only control is getting certain pieces of info out so that the public and Congress will mistrust him..but they have to get some Democrats on board since they have the votes.
I think it would be a good lesson for America to learn they actually let in a Russian plant.
However, are there many in our government who are culpable. Look at the Weather Underground guys. Nothing happened to most of them and the ones that went to jail got pardoned.
Someone in the government was working with them or protecting them.
As far as I know, the largest infilitration into the US Government was done by Scientology through Operation Snow White.
If Scientology could do it, then certainly the KGB could do it.
I guess I take a somewhat less sinister view of this issue. I think that people like Clinton (who toured Russia with help) and Obama may tacitly understand that they are dealing with leftists/radicals. Undoubtedly, these individuals and their related organizations have received funding and assistance from nefarious communist organizations.
However, I think that, rather than directly communicating with their protege or whatever, the communists consciously act as cheerleaders for their proteges. It would be too dangerous and damaging to have direct communications with their targets. Thus, any such "wayward" individual can consciously associate with these leftist causes yet have plausible deniability about being a a communist pawn.
I met a conservative fellow once who grew up in the 60s. He said that it was common knowledge that all of the senior leadership of SDS were rabid communists and that anyone who dealt with them (e.g., Clinton) were, in many ways, dealing with the devil. However, given the tight cell-oriented behavior of these organizations, one could claim to be a supporter or to be sympathetic, yet still avoid being called a communist sympathizer and the like.
A huge BTTT.
Ping the cranks to this thread, they'll eat it up.
Very interesting ping, to say the least.
Email this to everybody!!!
Even more than Obama, everything he did benefited the Soviet Union. The difference with Obana is that everything he does benefits Communism and accelerates the destruction of America.
Luckily, the Soviets did not have enough money to spare to do achieve that.
While on the subject of destroying America, among such efforts of the absolutely loony Obama advisers with his total support and encouragement is turning the nation's food basket of Southern California into a dust bowl for a bunch of minnows.
Even crazier is the proposal to DESTROY/REMOVE a couple of HUGE dams on rivers TO SAVE SALMON RUNS TO THEIR BREEDING GROUNDS!
Instead of building side, stepped channels for the salmon, Obama wants to destroy the dams and flood huge areas which it will take decades to restore - APART from the loss of power being generated by those dams.
Destroy, destroy, destroy under some idiotic ideological premises that would seem strange in a lunatic asylum. This is the same lunacy and any excuse to destroy the nation with his health care power grab nonsense,
Since a Democratic (or RINO for that matter) controlled Congress won't impeach him and the Supreme Court won't hear any citizenship cases, what are we to do? We can't wait another 3 or 4 years. He'll have this country looking like East Germany way before that!
I thought USSR declassfied docs after the USSR fell showed Carter was contacting Brezhnev trying to get the USSR to save his bacon in the 1980 election. All the money in the world was not gonna save Jimmy against Reagan.
Where did the $700 + million come to get Hussein elected?
By now, many should be realizing that Barry & co are driven by dreams of Cloward-Piven. Everything this lying bastard does has a goal of bringing down one societal buttress after another. If he is not stopped soon, the 2012 election won't matter. By destroying our economic resilience—yes, that is already a clear goal with cap&tax and obamacare—the quisling affirmative action figure has effectively painted the ultimate target upon our backs for al qaeda to 'exploit the moment'. If this bastard hasn't caused US to have another 911 event but perhaps much more deadly, within the next nine months, I will be astonished, actually. In fact, I expect it by Christmas of this year. And the democrat party is fully at fault yet they haven't a clue that they are causing this Republic to die. They think they are radically transforming US into their societal engineering dream, but they are only stripping US for the enemies to murder.
Thanks for the ping!
here's the link to the article that shows one son of Oginga Odinga went to East Germany and the other son to the Patrice Lumumba University.
Which entered into a MEU with de Muslims.
De Muslims is not necessarily a God Fearing family in the way American clingers would understand the term.
East Germany. Patrice Lumumba. Knee of Uncle Frank. Not necessarily God Fearing.
Oh, but, Barack KGB Obama is a Christian.
Its Eddie Murphy.
So, if there was an Odinga at the Patrice Lumumba University, it's not surprising there may have been an Obama there as well.
Oginga Odinga had four wives and seventeen children. Two were named Raila and Oburu.
Religious? Sure. Muslim.
In capitalist-oriented Kenya, newly independent from Britain in 1963, the Soviets and their East European satellites rushed to open embassies. Washington quickly followed, offering exchange programs in America for Kenyan students to offset the offers from Moscow universities. A prominent politician, Oginga Odinga, was financed by Moscow in his political struggle with the first President, Jomo Kenyatta, a tactic that served to reinforce American enthusiasm for Mr. Kenyatta.
AFTER THE COLD WAR: Views From Africa; Stranded by Superpowers, Africa Seeks an Identity
Moscow financing Oginga. Obama campaigning for, and providing counseling and financing for, his East German-educated son Raila.
Obama himself being a special project of CPUSA member Frank Marshall Davis.
from your link:
"...Moscow, judging the anticolonial fervor to be a good fit with Marxism, waded in first. In 1960, Nikita Khrushchev embraced African leaders at the United Nations, and Soviet embassies sprouted in barely known African countries...
That's where I begin my summary of the OBAMA AFRICAN COLONIAL story -
No Stanley Ann in Hawaii, but we have Obama Sr. by mysterious route and with mysterious authority--
--and we have Stanley Armour in a role confirming my suspicions he and Davis were fellow cell members, not merely whiskey and marijuana buddies.
Leaving a wider venue for Obama Jr.'s baby-daddy and birthplace/citizenship.
Your scholarship continues to be epic.
In case you missed any of this on FR or AntiMullah (not usually on both but sometimes)
thanks, there's much more there on that thread...when you have the time.
It is lunacy, albeit a very calculated kind. Obama has lined up rabid environmentalists, communists and a few big banks to destroy the economy, so he can take over everything . He promised a "New America" before the election. He just forgot the details.
You made some good points here, FARS. It's easy to see the destruction in terms of "liberal nuttiness" but maybe it's just plain old destruction...
Thanks for the ping!
What's an "E.G."?
Got it: Equatorial Guinea
"It's impossible for us to study. The universities have no money and our government has no money. We are hostages," said another countryman, Enrique Edu, 29, a law student at Baku University in Azerbaijan.
Ummm, would it be that hard to contact the other "students" and see if they remember ...
When he unlawfully got a copy of Ryan's divorce proceedings and used them to beat Ryan in Illinois with inuendo and lies. The gangster Obama has never changed.
I sometimes think we are now living in one. Every day brings new unbelievable announcements of Obama's intents - even though they are shrouded in devious wording to hide the truth.
Thank God for those of you who are strongly fighting it.
I am convinced that Obama is doing everything he possibly can to damage or destroy America. He does not have a background as an American, but is a product of third world,countries like Indonesia and Kenya.
I am beginning to feel like a broken record, but Barack Obama is the greatest threat to America that we face today. I keep asking myself how this creep ever became POTUS.
bump to the top
Please add me to your ping list.
I've read it before, but generally chalked it up as CT.
One aspect which appears to be false is the modus operendi of the drunken female with loose lips.
If her incentive is to win an argument by mentioning something that is supposedly very secretive, then she definitely spilled more beans than required to satiate such a desire. The level of detail described would have required extensive planning with branch and sequel plans to implement.
I have researched and found a possible connection. Read the original account from Mr. Fife and how he refers to a Mrs. T
Then check this link.
I think Dr. Tatyana Koryagina may be the Mrs. T in question.
Probably why his college records are sealed. I wonder how popular the name "obama" is? What are the odds of this being another "obama"? This story is really strange.
Seattle Times
February 13, 1992
As I recall, the Fife recounting said
the wife's name was T.M ... the husband's
Google the Frankfort School.
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Ebstein's Anomaly -- Child
- Home
- Health Information
- Ebstein's Anomaly -- Child
(Ebstein's Malformation—Child; Anomaly, Ebstein's—Child; Malformation, Ebstein's—Child)
|Heart Chambers and Valves
|Copyright © Nucleus Medical Media, Inc.
|Blood Flow Through the Heart
|Copyright © Nucleus Medical Media, Inc.
Risk Factors
- Chromosomal abnormalities
- Environmental exposure
- Certain medications taken by the mother during pregnancy
- Swelling in the abdomen and legs
- Blue or pale skin color
- Rapid heart beat or skipped heart beats
- Decreased energy
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- Ablation procedure—This procedure may be done if your child is having abnormal heart rhythms. A catheter is threaded up to the heart. Abnormal tissue is destroyed to stop the abnormal rhythms.
Lifelong Monitoring
Ebstein's Anomaly Foundation http://www.ebsteinsanomaly.org
Ebsteins Society http://www.ebsteins.org
Canadian Cardiovascular Society http://www.ccs.ca
Heart and Stroke Foundation of Canada http://www.heartandstroke.ca
Ebstein's anomaly. American Heart Association website. Available at: http://www.heart.org/HEARTORG/Conditions/CongenitalHeartDefects/AboutCongenitalHeartDefects/Ebsteins-Anomaly%5FUCM%5F307025%5FArticle.jsp. Updated November 19, 2015. Accessed June 3, 2016.
Ebsteins anomaly. Cincinnati Children's Hospital website. Available at: http://www.cincinnatichildrens.org/health/e/ebstein. Updated January 2016. Accessed June 3, 2016.
About Ebsteins. Ebsteins Society website. Available at: http://www.ebsteins.org/about. Accessed June 3, 2016.
Ebstein anomaly of the tricuspid valve. EBSCO DynaMed Plus website. Available at: http://www.dynamed.com/topics/dmp~AN~T114604/Ebstein-anomaly-of-the-tricuspid-valve. Updated January 25, 2016. Accessed June 3, 2016.
Symptoms and diagnosis of congenital heart defects. American Heart Association website. Available at: http://www.heart.org/HEARTORG/Conditions/CongenitalHeartDefects/SymptomsDiagnosisofCongenitalHeartDefects/Symptoms-Diagnosis-of-Congenital-Heart-Defects%5FUCM%5F002029%5FArticle.jsp. Updated October 26, 2015. Accessed June 3, 2016.
Revision Information
- Reviewer: Kari Kassir, MD
- Review Date: 06/2016 -
- Update Date: 05/30/2014 -