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2009 Barolo Brunate Roberto Voerzio
Bt (75cl)
Bt (75cl)
0 immediate, 6 marketplace
Average critic rating : 96.0 points
The 2009 Barolo Brunate shows the deft hand of its creator. This wine is amazingly focused and precise. Its aromatic elements are presented in startling detail: Spice, pencil shavings, small berry fruit, leather and tar compete for your attention. The elegance and finesse felt in the mouth is superb. Hold off from drinking this beauty for five years or more. Anticipated maturity: 2016-2030. ||The wines of Roberto and Davide Voerzio offer a fitting conclusion to this tasting of Piedmont's best red wines. These are stunning wines that capture, head on, the beauty of the 2009 vintage. They remind us of the dazzling heights achieved by the Nebbiolo grape. Wine Advocate.June, 2013
Azienda Agricola Roberto Voerzio is an Italian wine producer based in La Morra, in the heart of the Langhe area of Piemonte. The winery is known for producing top quality Barolo from some of the most prestigious vineyard sites in the region. In addition to Barolo, Barbera d'Alba, Dolcetto and Merlot are also produced at a very high level. The winery philosophy is simply to have the greatest respect for nature. No chemical fertilizers, fungicides or pesticides are used at all in the vineyards and vines are pruned heavily in the winter, leaving only 5-8 buds per plant. During the growing season the vineyards are maintained meticulously with heavy green harvesting, pruning and leaf thinning, resulting in a very small but high quality production. The yields at Roberto Voerzio are said to be the lowest in the region. In the winery, fermentations are carried out as cleanly as possible with only native yeast being used and no use of additives that can alter the flavour profile of the wine. All of the wines are bottled unfiltered in order to maintain their intense flavour concentration, though they are known to be bright, elegant and light on their feet stylistically. The winery recommends a minimum of 5-6 ageing in the bottle before they are opened; however, they will evolve over 2-30 years if kept in optimal conditions. The production at Roberto Voerzio is limited; with 20 hectares under vine, only 40,000-60,000 bottles are produced depending on the harvest. With remarkable pedigree, massive ageing potential and consistently high scores from James Suckling and Antonio Galloni, the Barolo from Roberto Voerzio is not to be missed.
See all wines from this Producer
FINE+RARE offers UK home delivery through our logistics partner London City Bond, with next day deliveries available for Central London addresses.
We deliver Monday to Friday; charges are £ 16 + VAT for up to 10 cases (12x75cl or equivalent) for most UK postcodes.
For delivery charges to Highlands, Islands and outlying areas, please contact our Customer Service Team.
For deliveries into Hong Kong and Singapore, we offer a dedicated air and sea service.
For more details regarding delivery to Hong Kong, Singapore and all other destinations, please view our International Delivery information page.
Spirits cannot travel on our services to Hong Kong, Singapore or Macau and require separate shipments. Please contact our Customer Service Team for further information.
Our storage costs are highly competitive. We will happily accept cases or single bottles, charging pro-rata based on the number of bottles and length of storage period.
Unlike many other wine companies, our service includes storage of duty paid wines as well as in bond from any reputable source, not just those bought through FINE+RARE.
Please visit our F+R Storage information page for more details.
FINE+RARE can arrange delivery of your wines to your personal fine wine storage account:
Deliveries within London City Bond or to a Vinotheque storage account are charged at £ 8 + VAT for up to 10 cases (12x75cl or equivalent).
Deliveries to all other storage providers are charged at £ 16 + VAT for up to 10 cases (12x75cl or equivalent).
Please contact our Customer Service Team if you have any questions.


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Quick access
I have 2 problems,
1) a machine I need to use for debugging will not show the scanners plugged into it in my dialog but will in windows scan and fax, the same scanners show in windows 8 and other win 7 machines.
2) i'm trying to debug why the app crashes when the transfer is called on windows 7 only.
Scan And Fax for windows shows my 2 scanners on windows 7 but using a custom app that implements native WIA in c++ it does not show the scanners in the select device dialog.
This app works fine on windows 8 and some other windows 7 machines although it crashes when doing the transfer with the below crash info.
Problem signature:
Problem Event Name: APPCRASH
Application Name: DocumentImportManager.exe
Application Version: 184.108.40.206
Application Timestamp: 50f9c275
Fault Module Name: sti.dll
Fault Module Version: 6.1.7600.16385
Fault Module Timestamp: 4a5bdb14
Exception Code: c0000005
Exception Offset: 00015568
OS Version: 6.1.7601.2.1.0.256.48
Locale ID: 1033
Additional Information 1: 0a9e
Additional Information 2: 0a9e372d3b4ad19135b953a78882e789
Additional Information 3: 0a9e
Additional Information 4: 0a9e372d3b4ad19135b953a78882e789
2) is fixed by removing IWiaAppErrorHandler from my callback class. some reason sti.dll was getting access exception after the return of this instance from QueryInterface
1) still happens but the device is there if I enumerate it and not use SelectDeviceDlg

subset: commoncrawl


text:
A pair of former contestants on "The Ultimate Fighter: Latin America," including one season winner, will meet at UFC 211 in Dallas.Filed under: News, UFC read news >>
Joe Stevenson isn't a newbie to the Octagon. He's not new to The Ultimate Fighter either. Nor is he new to the battle with addiction. read news >>
The Ultimate Fighting Championship released the attendance and gate numbers stemming from Fight Night Halifax following Sunday's event in Nova Scotia, Canada. read news >>
The Ultimate Fighting Championship announced the recipients of the $50,000 fighter bonuses from UFC Halifax following Sunday's event at Scotiabank Centre. read news >>
Check out the main card face-offs from the UFC Halifax: Lewis vs. Browne Ultimate Media Day ahead of Sunday's fights in Halifax, Nova Scotia. read news >>
Preview Fight Night Halifax with the ultimate fight-by-fight breakdown. read news >>
14 former cast members will compete for redemption in the tournament comprised of welterweights and the largest cash prize in the show's history. read news >>
The 14 cast members for "The Ultimate Fighter 25" have been revealed, and a pair of former winners – not to mention a handful of former finalists – are on the list.Filed under: Featured, News, UFC read news >>
Remember back when Josh Koscheck was the UFC's ultimate heel? When he was feuding with Georges St-Pierre and whomever else he faced, camera crews fell all over themselves to record the Kos flying in read news >>
The landmark 25th season of FS1's highest-rated and most-watched original series, The Ultimate Fighter® premieres Wednesday, April 19 at 10 p.m. ET on FS1. This season 14 former cast members will com read news >>
The Ultimate Fighting Championship crowned its first women's featherweight champion at UFC 208, but Cris Cyborg says everyone knows she's the champ. read news >>
According to an Ultimate Fighting Championship impact study, UFC 205 set numerous records and pumped millions of dollars into New York's economy. read news >>
Ultimate Fighting Championship announced the fighter bonuses stemming from UFC 208 following Saturday's event in Brooklyn, New York. read news >>
The Ultimate Fighting Championship officially announced UFC on FOX 24 on Saturday night, revealing four bouts for the card. read news >>


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Oregon town feeling ignored on future of depot
IRRIGON, Ore. — The city manager of Irrigon says the town has been overlooked in the planning for future uses of the nearby Umatilla Chemical Depot after its stockpile of obsolete Cold War weapons is destroyed.
Jerry Breazeale said the town wants to team with the communities in the region to promote economic development and job creation and had prepared a notice of interest about acquiring some depot land for development.
But he said the notice to the group in charge, Local Reuse Authority, was ranked last among 12 projects.
He included a copy of that vote, and a chronology of the city's efforts to have the authority recognize its application, in a letter sent this week to LRA members.
LRA members denied that Irrigon was treated unfairly.
"I feel the reuse plan adopted last week is the best for everyone in this area, Oregon and the nation," said George Anderson, an attorney who has been involved with depot issues for more than two decades. "I also feel the city of Irrigon was given a fair hearing at all stages of the process."
In its request, the town asked for two miles of the depot for use as industrial land, as well as plans that would allow access from the Union Pacific Railroad's main line to rail lines on the depot; a proposed wind project and possible solar project; storage; and agriculture use on Army land outside the depot.
Three of the six subcommittee members — Rod Skeen, of the Confederated Tribes of the Umatilla Indian Reservation, Gary Neal, of the Port of Morrow, and Kim Puzey, of the Port of Umatilla — gave zero points to Irrigon's notice.
"There is no way that the NOI could receive a zero unless the proposal was blank," Breazeale said.
Puzey noted that Irrigon already was represented on the LRA by Morrow County and the Port of Morrow. Irrigon Mayor David Burns said Irrigon tried to cooperate with members, but couldn't get through.
"The cities have come out on the short end on this thing," Burns said.
Click here to comment on this story »


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Products & ServicesSee also: Categories | More Information
Description: Applications Components for chemical processing, offshore oil/gas platforms, pulp/paper production, desalination plants, marine application, flue gas scrubbers and food processing. Description AL-6XN® is low carbon, nitrogen bearing super austenitic stainless steel. The alloy was designed
Show More
- Metal / Alloy Types: Stainless Steel (UNS S)
- Standards / Specifications: ASTM / ASME, UNS
- Shape / Form: Foil, Semi-finished Shape / Mill Stock, Strip, Wire / Shaped Wire
- Coil Stock: Yes
Supplier: High Performance Alloys, Inc.
Description: to Type 304S.S. This grade is best known for its wear and galling resistance. The additions of Silicon and Manganese have given this alloy a matrix to inhibit wear, galling, and fretting even in the annealed condition. Higher strengths are attainable through cold working the material and is still
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- Metal / Alloy Types: Stainless Steel (UNS S)
- Standards / Specifications: ASTM / ASME, UNS
- Shape / Form: Profile / Structural Shape, Bar Stock, Flats / Rectangular Bar, Squares / Square Bar, Semi-finished Shape / Mill Stock, Other
- Tensile Strength (UTS, Break): 95000 to 105000 psi
Supplier: G.L. Huyett
Description: Ground flat stock is made from general purpose tool steel containing manganese to make it nondeforming and non-shrinking. It's used in toolrooms for tools, dyes, punches, templates, stripper plates, and in tight tolerance keyways.
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- Metal / Alloy Types: Alloy Steel (UNS G), Stainless Steel (UNS S), Tool Steel (UNS T)
- Standards / Specifications: ASTM / ASME
- Shape / Form: Bar Stock, Flats / Rectangular Bar
- Overall Width / OD: 0.1250 to 14 inch
Supplier: RS Components, Ltd.
Description: Material = Silicon Chrome Manganese Steel
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- Drive Type: Slotted
- Overall Length: 3.58 inch
Lithium Batteries - Battery; Lithium/Manganese Dioxide; 3.0V (Nom.); -20 degC; degC; 7.18 -- 70149234Supplier: Allied Electronics, Inc.
Description: Lithium⁄Manganese Dioxide Battery, 3.0 V Nominal Voltage, 17.0 gm (Avg.) Weight Flat, Recessed Negative Terminal, Nickel Plated Steel Provide Very High Density and Excellent Rate Capacity Provide Up to Four Times the Power of Alkaline Batteries Provide Wide Operating Temperature
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- Voltage: 3 volts
- Operating Temperature: -4 to 167 F
- Lithium Secondary Batteries: Lithium / Manganese Dioxide
- Standard Battery Sizes: 2/3 AA
Wirewound Resistors - Resistor;Wirewound;Res 15 Kilohms;Pwr-Rtg 10 W;Tol 1%;Lug;Alum Housed;Military -- 70200365Supplier: Allied Electronics, Inc.
Description: , steatite or alumina core (depending on size). Copper-nickel, manganese copper or nickel-chrome alloy element (depending on resistance value) with stainless steel end caps and tinned Copperweld® terminals. –55°C to +275°C operating temperature range.
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- Resistance Range: 15000 ohms
- Tolerance: 1 +/- %
- Temperature Coefficient (TCR): 20 ±ppm/°C
- Power Rating: 0.0134 HP
Supplier: U.S. Alloy Co.
Description: Specifications AWS A5.28 Class ER80S-D2 Description USA 80S-D2 is designed to give high strength weld son high sulfur bearing (free-machining) steels or medium carbon steels. This wire contains additional amounts of manganese and silicon which, when alloyed with 0.50% molybdenum, produces weldShow More
Supplier: Waterman Industries, Inc.
Description: 304 stainless steel. Hinge bushings are bronze. Gate features a minimum of 2 1/2 degree seat incline to assure positive closing. Finished seating faces are machined to a flat plane within .002 T.I.R. Optional dovetail beonze seat faces, stainless steel seat faces, and a dovetail neoprene seat
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- Valve Type: Gate / Knife Valves
Supplier: Eriez
Description: balanced to make full use of the magnet's high permeability steel members for most efficient magnetic field distribution, produces maximum-force density at a selected working distance from the magnet face. The magnet is fabricated from heavy-steel plate with a thick, manganese, steel bottom plate
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- Magnet Type: Suspension Magnet
Supplier: Hobart Brothers, an ITW Company
Description: of manganese and silicon to control porosity, provide radiographic quality welds and produce a smooth, flat bead. Applications Single or multiple pass 75 Argon/25 CO2 or CO6 Industries High temperature service piping, construction equipment, trailers, cranes, and high tensile strength applications. Root
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- Alloy Type: Steel - Low Alloy Carbon
- Form / Shape: Solid Wire
- Diameter / Thickness: 0.0350 inch
Supplier: LECO Corporation
Description: ), LECO products include setters, saggers, pusher plates, hearth plates, and kiln furniture. LECO ceramics are ideal for melting steel, aluminum, chromium, copper, iron, silver, manganese, nickel, ductile iron, gray iron, and cobalt-based metals. Each ceramic product goes through a rigorous testing
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- Crucible Products: Crucible - Cylindrical (Straight wall)
- Bottom Type / Pour Method: Flat Bottom
- O.D. / Width: 3.25 to 19.25 inch
- Height: 4 to 21 inch
Supplier: Hartchrom, Inc.
Description: lubricity, oil retention and release properties. Hartchrom can handle cylindrical part sizes up to 80 in. in diameter, 450 in. long and up to 35 tons. Flat plates and similar items up to 110 in. wide and 450 in. long can also be accommodated in one of our three large plating tanks. Both outside
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- Plating Processes: Chrome Plating - Hard
- Material / Substrate: Iron / Cast Iron, Metal, Nickel / Nickel Alloys, Stainless Steel, Steel / Steel Alloys
- Additional Services: Electropolishing, Hydrogen Relief Baking, New / OEM Parts
- Industry: Aerospace, Architectural / Construction, Automotive, Chemical / Material Processing, Energy / Utilities, Food & Beverage, Government, Machine Tools, Maintenance / MRO, Marine, Military Specification, OEM / Industrial, Oil & Gas, Process Equipment, Steel / Metal Mills, Vessels
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From the storage piles, the feldspar is fed into a 9" x 16" Reliance jaw crusher, equipped with flat manganese steel jaw plates, designed for finecrushingand set to deliver 1/2-in.product. This crusher is driven from a 20-horsepower motor and …
Selected abstracts of metalworking literature July 1983–March 1984
Rolling of Silico- Manganese Spring Steel Flats in Mini Steel Plants in Developing Countries.
Journal of the Aeronautical Sciences (Institute of the Aeronautical Sciences) > On the Mechanism of Friction
Besides copper and copper alloy targets flats of manganese steel were used; how- ever, the sensitivity which was attained by deuteron bombardment of manganese steel was considerably less than that achieved with copper alloys.
Federal Register > Friday, July 12, 2002 > [67 FR 46221] Exclusion of Particular Products from Actions under Section 203 of the Trade Act of 1974 With Regard t...
(xxxviii) Austenitic manganese steel round and flat bars (Bohler K700), with chemical composition (percent by weight): carbon 1 to 1.3, silicon 0.10 to 0.45, manganese 12.00 to 14.00, phosphorus 0.035 maximum, sulfur 0.040 maximum, chromium …
Influence of inclusion characteristics on the formability and toughness properties of a hot-rolled deep-drawing quality steel
During hot rolling of flat steel products, manganese sulfides, which are plastic at elevated temperatures, are elongated in the rolling direction.
… tongs High-impact service; tail Austenite sattwatedwith Heat to reaustenifize; Excellent Low yieldpoint Poor; grind if required tracks, frogs, switches; carbon; ironwatexquench deformation use on caIbon or manganese carbides at grain boundaries in manganese steel base thin, flat , brittle plates Agricultural rnachinea'y …


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If your existing garden furniture requires a lot of attention and maintenance, then why not consider something totally new and practical? The Keter Allibert Carolina Set is ideal for busy people who don't want the hassle of yearly garden furniture maintenance. This set will change your mind on how garden furniture can enhance your life and bring you joy. The set consists of a two-seater sofa, two armchairs and a coffee table. Such a set will be ideal for a small balcony or even in a conservatory.Practical Rattan Effect
The furniture set is different from other sets. It doesn't have a traditional look because of its woven effect and colour. But this design style is seen the world over in hotels and spars, and you can now enjoy the same modern look but with all the practical elements of great furniture right in your garden. This rattan effect has great weather-resistant properties and its anthracite colour won't fade in the sunshine. This set won't rust and the material makes it lightweight so it's easy to move around.Perfectly Themed Set)
You can be sure the Keter Allibert Carolina Set will be the location of many great moments in your summer. It looks inviting and relaxing and your guests will want to come over again and again. The sofa can comfortably seat two people, the arm rests are low so they won't get in the way but are still great to lean on. The back of the sofa is contoured so it provides great support. The armchairs are similar in style to the sofa but only seat one person. All of the seats have a plush ivory cushions for added comfort. The coffee table complements and completes the set.
The set is composed of two armchairs (Approx. Width 65cm x Depth 66.5cm x Height 76.5cm), sofa (Approx. Width 129cm x Depth 66.5cm x Height 76.5cm) and a coffee table (Approx. Width 92cm x Depth 58.5cm x Height 43cm). You can choose between natural-coloured cushions or the grey variants, whichever you think will be make your space fancier. Nonetheless, make your indoor or outdoor relaxation a sweet treat by having the Keter Allibert Carolina Lounge Set!
This coffee table matches the sofa and chairs with the same rattan effect finish. The stylish anthracite colour ensures the whole set stays ahead of fashion and will always look great in outdoor space. The table is 77cm high which is ideal as you won't be reaching too high or low for your drink or magazine.
You'll never have to worry about having everyone squeeze onto one old sofa. With this set, you can make sure each of your guests will be comfortable and spaced out. The armchairs are easy to position so you can sit close together.
|Natural Cushions
|Grey Cushions
|Table Width
|Table Depth
|Table Dimension
|92cm x 43cm x 59cm
|92cm x 43cm x 59cm
|Table Height
|Chair dimensions
|65cm x 77cm x 67cm
|65cm x 77cm x 67cm
|Chair Width
|Chair Depth
|Chair Height
|Natural Cushions
|Grey Cushions
|Natural Cushions
|Grey Cushions
|No. of Seats
|Table Shape
|Table Style
|Chair Style
|Fixed, Armchair, Fixed Armchair
|Fixed, Armchair, Fixed Armchair
|Cushions Available
|Yes - Standard with this package
|Yes - Standard with this package
|Parasol Available
|Furniture Type
|Lounge Set
|Lounge Set
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This Classified is Closed
For Sale:
Fiio E9 - Like new with Fiio D3 bonus - all original packaging for E9 with all accessories
Will Ship To: United States
This is a original Fiio E9, not the new version that is compatible with the E17 (name - E9K), but is compatible with E7. I'm throwing in a D3 at no extra cost - didn't have a need for it anymore. In the second picture it looks like the E9 has a smudge on it, it doesn't my phone is not very high quality for photos so I apologize in advance. I assure you that the unit is in pristine condition.
Edited by GN3RAL KARL - 11/10/12 at 12:35pm


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Diana Krall
Semi-stranded in the Czech Republic in April 2002, I found succor in Canadian crooner Diana Krall's The Look of Love, an easy-riding pop-jazz confection that feels like a million bucks when you're staring down your third meal of conspicuously vegetable-free goulash a fellow traveler more accurately dubbed "oil soup." Pre-Norah Jones, Krall nailed the sound of consenting adults luxuriating in a privileged mental space of svelte sophistication--quite attractive, I admit, compared with one more night on the hardwood floor of an unheated squat. Krall's new album, The Girl in the Other Room, nails something else: her and new husband Elvis Costello's attempts to make music perfect for entertaining in their New York apartment. (An acquaintance painted it, and says it's huge. True!) As such, it's kind of a snooze. Half of Room's 12 tunes are Krall-Costello co-writes, including one called "Abandoned Masquerade" that I won't quote out of respect for, well, lyrics as a concept; the title track is better because Anthony Wilson's guitar shimmers like chardonnay. But even the good stuff here lacks Love's breezy sensuality, the seductive sheen that made me miss the shit out of Banana Republic two years ago. Looks like Costello made off with more than Krall's party dress.
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Kids grow up so quickly, and it often seems like the ones who have an older sibling grow up faster. Such is the case with my grand niece, Hattie Joy Parmely. Hattie is turning two years old today, but with the help of her sister, Reagan Parmely, she just seems older than two. When I think of a two year old, I think of a child who is trying to learn to pedal a tricycle, but instead, Hattie rides a Strider. Now for those of you who don't know, that is a bicycle with no pedals. Instead of pedaling, the rider uses their feet to basically run the bicycle down the road. I realize that this method is not like riding a bicycle exactly, but it does take a degree of coordination, and Hattie has mastered it very well.
Lots of kids like to climb, but I'm not sure I have seen too many that can climb a stack of hay bails. Granted, once again, Hattie had the help of her big sister, Reagan, and in the end just a little push from her mommy, Ashley Parmely. Reagan didn't initially realize that Hattie needed help, but Hattie let her know…in no uncertain terms, saying, "Reagie, help me!! Help me Reagie!!" And of course, Reagan did help her. Very soon Hattie was up on that bale of hay, right beside her big sister, because, while she is only two, that does not mean she can't do the things her big sister does…just watch her, if you don't believe it.
Hattie and her family live in the country, and they have lots of animals to take care of. Hattie and Reagan aren't one bit scared of the animals, and in fact I think they think of them more as their babies. So while most little girls are playing with dolls, these girls are playing with goats, chickens, and horses. They help to care for them, and get to ride the horses, and eventually they will learn the ropes even more, although, cleaning up after them might not be the thrill of their days. Still, as the saying goes, "It's a dirty job, but someone's got to do it." And as kids get older, they learn all the ropes of having animals.
Hattie looks so much like her daddy, Eric Parmely, and we all thought her sister Reagan did too, but as Reagan has grown, she has started to look more like her mommy. I suppose that time will tell, as to whether or not Hattie will start to take on more of her mommy's features. We will just have to wait and see what the future brings. Today is Hattie's 2nd birthday. Happy birthday Hattie!! Have a great day!! We love you!!
It's really hard for me to believe that my grand niece, Jaydn Mortensen is twelve years old today, but she is, nevertheless. Jaydn has done a lot of living in her relatively few years. She is the only child of her parents, my niece Amanda Reed, and her significant other, Sean Mortensen, and they like giving their daughter a full life. She has never been made to feel like she is too little to be around the adults, and so, she has been four wheeling, boating, and snowmobiling with her parents and their friends. Jaydn's family loves all kinds of outdoor sports, and so it stands to reason that Jaydn does too. I think her extensive time at Seminole Reservoir has probably turned her into a fish…so to speak. He parents spend every possible weekend at the lake, and that means lots of activities.
Sports aside though, I think that Jaydn's true love…for now anyway…is horses. She has such a way with them. She loves to ride them and take care of them, and she isn't afraid of them, even though last summer started off badly, when she was bucked off of a horse, breaking both of her arms. What a way to start the summer vacation. That didn't deter her at all. Jaydn is very much into all things animal, and especially if it relates to the fair and rodeo. She has started showing horses, and is really quite good at it, to which her ribbons will attest. In her first horse showing, she took 4 Grand Champion, and 1 Reserve Champion in horse. She was also voted Outriders Princess last year, which is the best of the best…but then we knew that.
Every year, Jaydn gets better and better at the things she loves to do. I don't know what her future goals and dreams are, and maybe she doesn't know either, but I think she would be a great veterinarian or some other such occupation involving animals, because she simply has a way with them. She doesn't just love horses, although, they are her true love, but she likes goats and rabbits and other animals too. I think she just has a heart for animals in general, and it's obvious from what I've seen, that they love her too. Today is Jaydn's 12th birthday. Happy birthday Jaydn!! Have a great day!! We love you!!
My grand niece, Raelynn Masterson is turning 13 today. Turning 13 is an exciting, mixed up, trying time in that persons life, but Raelynn…or Rae, as she is known to her family, is taking it pretty much in stride. She has always been easy going, and maybe it's that style that lets her make a smooth transition into the teenage years. The journey from child to young adult is filled with ups and downs, but Raelynn doesn't seem to be too shook up about it…unlike her mom, my niece, Dustie Masterson. Dustie is having a bit of a hard time believing that her first born…while no longer a baby, yet always her baby, is growing up so very fast. Dustie calls this by far their "biggest adventure" yet. I think that any parent of children over the age of 13 knows exactly what Dustie means. I don't think any parent is truly ready for their kids to grow up.
Raelynn is the big sister to Matt and Anna, and younger half-sister to Christina, who lives in Colorado. For some time now, Raelynn has been the "little mom" to her younger siblings. She is helpful to her mom and dad, and doesn't present them with a ton of drama…unless her younger brother and sister provoke her, that is. She is so motherly sometimes that her mom has to remind her that in reality she is not the mom, but that often happens with older children. She is a kind person too, so I'm sure that keeps sibling relationships on an even keel. Many people really have no ability to empathize with others, but Raelynn is compassionate and has an understanding of people that surpasses her years on this earth.
These days Raelynn is into science and boys…and not necessarily in that order. I suppose that might be viewed as an odd combination, but it works for her. The Science Zone is a really big deal here in town, and she loves going there. They even have summer classes for the kids. Dustie signed Raelynn up for three this year. The first one was a Dissection Class, and is definitely the one Raelynn likes the least…probably because of her love of animals. The second class was on Water, which she really enjoyed, but it was the class where she was able to help the instructor with the animals that really did it for Raelynn. When her mom picked Raelynn up, she was excitedly telling her that the Iguana and the Science Zone doesn't like anyone, but really took to Raelynn. She was so happy about that. Raelynn loves to read, and is keep a journal, which is seriously private, of course. Raelynn is such a sweet girl, and a great blessing to her family. Today is Raelynn's birthday. Happy birthday Raelynn!! Have a great day!! We love you!!
Children are a curious bunch. There is so much in this world that is totally new to them. Things we take for granted as being average, or even boring, they find interesting, and children aren't alone in this either. Animals can be just as curious about the things that people don't even think about. Things like taking pictures of seagulls can have them looking at you like you are from outer space. I suppose they have seen enough humans to know what they look like. Then to see one with a camera up to their face, makes them think that this is some new creature. As I scrambled to take this shot of a seagull as it flew over me head, I had no idea that I had snapped a shot of him looking right at me, as if to ask, "What are you doing?"
Dogs are especially curious about things, and since they aren't afraid to come near humans, they come and stick their curious little noses right in the camera lens…and they are very likely to lick the camera lens…whether you like it or not. In a way they are like babies. The best way to figure out what something is, is to put it in your mouth…right?? Well, that's just like a dog. If it's cool enough for their human to have up to their face, it must taste good. Or maybe it's a new kind of toy that their human bought for them. Maybe if they lick it and let their human know they want to play, their human with throw it for them. As funny as that sounds, the photographer probably isn't so thrilled with that dog slobber all over their lens, but their dog is having a great time.
When it comes to kids though, they have a little bit more ability to get their hands on things. A wise parent knows that there is a time to kid proof your house. It doesn't matter what it is, if their parents think it's cool, so do the kids. And they don't understand the concept of something being broken. They just want to see what it is.
My grand nephew, Jake Harman was very much that curious little boy, when his mom or grandma was trying to take his picture. I can't say that the picture turned out the way they had planned, but you must admit that it turned out pretty cute anyway. If I didn't know what he looked like as a little boy, I suppose this picture could have been a picture of any baby, but it isn't, it's Jake. Jake was always a curious little boy, and I suppose that like most kids, that got him into a certain degree of mischief, but he was, in all reality just a normal boy, curiosity and all. And while the picture didn't turn out as planned, it takes me back to when my first grand nephew was born. It was a new experience, and we were all curious about who he would become. Hmmm…curiosity isn't just a quirk of children and animals. Even adults have that tendency.
Most kids love to go to the zoo, and it is a special treat if they have to go to some other town to go, such as visiting relatives. I don't recall going to the zoo as a kid, but I'm sure we must have. I remember taking my girls to the zoo in Denver, and they loved it. These days the zoo usually even includes the aquatic area. You can go and spend the whole day there.
Back when my Aunt Laura was a little girl, the zoo was very different than it is now, but the draw was the same. When a child can find themselves so close to wild animals, it is as much a rush as it is for adults. For Aunt Laura, this was a red letter day. I think it was for my grandmother as well, because she wanted pictures to remember the event. I have to wonder what a zoo looked like back then…was it primitive, with just fenced areas around the animals' habitats, or was that just what the particular area they were at when the picture was taken. My guess is that no matter what it looked like, my Aunt Laura was beside herself with excitement to be going. I know that is how I would have felt at her age. I can imagine how wonderful the day was for a little girl. Strolling along in the sunshine with her mom, looking at all the different animals. It must have been almost like a class field trip for her, except that she was not in school.
These days, the zoo is pretty much a common thing. Most people have been to one at some time in their lives. But back then, not so much. For my Aunt Laura, it was a day she would always remember, and I think it felt that way for her mother too. It appears to have been a ladies day out with family, and that probably made it even more special. Nevertheless, the most special thing to any kid is going to be the animals. There is always time to be excited about being with relatives, after all. But the Zoo…well, that's the coolest thing ever!!
Anytime you read through a well written family history book, you are bound to find things out about your family members that you never knew…even if you knew them all your life. The big thing is, I guess, that sometimes when things are in the past, they are viewed as ancient history. We all do things when we are young that we don't continue into adulthood. I knew many things about my Aunt Ruth through the years. She loved animals, gardening, and the mountains of Washington. She was an artist both in paintings and music. She painted a picture of herself that I would have thought was painted by a professional artist…along with other paintings. She could play any instrument that she picked up, as if she had been playing it all her life. She knew things about the weather that surprised me as a child…like the time they were at our house. Aunt Ruth suddenly jumped up and looked out the window. She said there is a tornado somewhere. I thought she saw something, but it was the way the wind suddenly stopped where we were that caused her to think that. I heard later that a small twister was reported on Casper Mountain. I never forgot that she had somehow known.
As I said, I knew Aunt Ruth loved animals, and I had seen pictures of her with several horses. I could tell that she was a pretty good horsewoman. I never had very much to do with horses, so seeing her seated firmly on her horse as he reared up, struck me as an amazing feat. And I knew that the family owned horses, and all the kids, my Aunt Laura, my Uncle Bill, my dad, and Aunt Ruth, road regularly, but never was there any mention of racing except in what I read today. Uncle Bill was describing the scene of one of the pictures he had put in the book, and he said that the horse was Aunt Ruth's race horse, which she did ride in some races. He doesn't specify how she did in the races she ran, but if it is like pretty much anything else Aunt Ruth did, she was probably pretty good at it.
I had to wonder why I had never heard about her racing before, and if I was the only one in the family who didn't know about it? Why was it that Aunt Ruth never talked about racing? I also wondered if it was something that she thought about doing professionally as a young girl, or if it was always just something she did to pass the time and to test her horse. If no one else in the family knew about her racing either, I suppose that it is something that will drift into the unknown past…except for that one little mention of it in Uncle Bill's family history books.
As I started up the walk to my house today, two birds, who were chasing each other buzzed by my head. They were so busy with their play…or was it an argument, that they didn't even notice me, as they flew very close to my head. I have always liked watching the birds in all their activities, but have normally had very little real contact with them. And while I find it fascinating to watch them playing chase, I'm not sure I really want them to be buzzing my head, or dive bombing me.
I watched as the birds flew here and there, chirping and chattering, and I occurred to me that they were probably having a little argument, and if the one bird caught the other…well, someone was going to be sorry they said or did what they did. I guess things in the animal kingdom must be similar to things in our world, because when you get in trouble, you have to pay the consequences in both.
The thing was that these two birds didn't seem like parent and child, so I figured that this was an argument between two adults, whether they were male and female, or two males fighting over a female. It is, if course something I will never know, nor will I know if they were fighting or playing. It was a chance encounter with the animal kingdom that will likely not happen again.
I suppose that when we live in the same world space as the animals, these encounters are going to happen once in a while. One or the other of us, or even both, simply aren't paying a lot of attention to those around them. Like most of us, when we are in an argument, they pay very little attention to anything but the argument. That is exactly what those birds were doing. I might not have even been in the area for all they noticed. They were simply too busy chasing each other.
Easton is like most little boys. He hates the whole dressing up thing that many parents are always wanting their kids to do. In fact, if he could figure out a way to get out of ever dressing up, he would do it. I think most men would have a tendency to agree with Easton…especially when it comes to wearing a tie. They just hate that tie. It chokes them, and if they are at all claustrophobic, it can make them feel like the walls are closing in. And for a little boy, it is even worse. I suppose it could be likened to sitting in a corner, or time out. In fact, time out probably says it all, because just as soon as they dare, little boys are asking, "Can I please take this tie off??" That is, if they ask to take it off at all.
Easton had finally had enough, and so he untucked his shirt and loosened his tie. He hoped that his mom wouldn't notice, and in the end, his hopes were realized. His mom, my niece, Machelle took the picture without even noticing the tie was loosened and the shirt untucked. It was Easton's Aunt Susan who would notice the sneaky maneuver her nephew had pulled off. By that time, there was nothing left to do but laugh at the fact the Easton had won…that battle anyway.
Now, if you were to put Easton, and most other little boys, in a different situation, you would find that they are totally comfortable. That situation would be, of course, camping. There is nothing better, in the mind of a little boy, than the adventures you can have while camping in the wilderness. All sorts of things can happen out there, and everyone will need a hero to save them from whatever danger might lurk just outside of the eye view of the camp. There could be wolves, bears, snakes, and many other such wild animals, but their moms can relax, because these boys will save them from that. They are big tough campers, and everyone knows that any self respecting wolf or bear, or even snake, would run from them. And that is the main reason why moms must understand that real boys, hate that tie. They are simply too macho for their tie!!
Today is Easton's 9th birthday. Easton, I hope you don't have to wear that horrible tie!! I mean, really Machelle, get a clue!! Real boys are too macho for a tie!! Happy birthday Easton!! Have a great, tieless day!! We love you!!
There is so much controversy these days concerning guns and gun control, and while I don't usually write about political events, this one hits close to home for me and my family. For many years, my Uncle Bill was a gun dealer. He and his family had always had guns. He became interested in antique guns at some point and began to collect, deal, and show the guns at gun shows all over the north central part of the United States, and possibly even in the north west part, as well. Uncle Bill and my dad, as well as their sisters were raised around guns, and yet not one of them ever killed someone.
My family and my husband's family have been around guns all our lives too. Our parents have hunted, as have many of us children and our spouses. If you live in Wyoming, as in many other places, owning a gun is really not so unusual. It doesn't, however, give any indication that the gun owners here, or anywhere else are likely to commit murder. And, while people who torture animals, often move on to killing people, hunters usually do not. Legal hunters have a respect for the animals they hunt. It is to provide food for their family, that the hunter hunts.
For centuries, people have owned guns, and during all those years, mass school shootings were unheard of…until recently. Christians, like myself, mostly agree that it is largely because we have kicked God out of our schools. That makes so many people angry, because they think we are talking about God being angry at the schools because He was kicked out, but that isn't it at all. In my opinion, when we removed God from our schools, we stopped teaching morality. Generations of kids have grown up with a changed view of right and wrong. Then those same kids are out there making television shows, video games, writing books, creating pictures, and so many other things that our impressionable kids are viewing. Wrong has become right…if it seems right to the person doing the wrong. It has become a matter of "the devil made me do it" or simply a matter of not allowing anyone to step on our feelings. It has become a good thing to be bad, and a good show is called wicked.
I think, that is we want to change things in this nation, we need to change what we are teaching our kids in school, and in life. Guns don't kill people…people kill people, and very often, guns are not the weapon of choice, in fact, guns are used the least amount of the time. We can't remove every possible weapon for the hands of people, unless we want to live in a Nerf world, and even then, people will use their hands, or they will just use rocks. We have to start teaching our kids and our adults the value of human life, and to respect each person's right to life. We have to realize that few people intentionally set out to hurt the feelings of others, and as with bullying, the ones who do need to be swiftly punished. We need to stop looking at others as less important than we are, and treat each person with respect, no matter how the look, talk, and no matter what their race, gender, or age is. Our ancestors carried guns for many centuries, and did not shoot up schools or other public places in order to make a point, possibly because of the values our nation started on. Maybe we need to work to make all people feel like they are a person of value, because it isn't the gun that kills, it is the person bent on revenge who kills people.
My daughter, Corrie's family all love pets. No matter how much work they can be, they cannot imagine life with out their furry friends. Their newest addition was Molly, who is a miniature dachshund. Like many animals, Molly has her favorite person/pet out of the family. For Molly, that person is Josh, my youngest grandson. Molly does not appreciate it when Josh is not there There are rules, after all, and Josh is supposed to always be at home, or at the very least, take Molly with him. The latter doesn't seem to bother Josh much either, in fact, last night he tried to take Molly to Youth Group at our church, which would normally be a problem, but last night it wouldn't have mattered too much since Josh was the only kid there, and the teacher is my niece, Jessi. I'm quite sure they would have had a wonderful time with Molly. Nevertheless, Corrie caught Josh, and wouldn't let Molly go. I'm quite sure they were both unhappy with her over that one. In fact, I'll bet Molly practically glared at Corrie.
As far as Molly is concerned, Josh is her pet, not the other way around. She has it in her head that Josh should be with her all the time. School and other activities are just not allowed unless Molly gets to go too. That is ok with Josh most of the time too, but there is the small matter of homework. Molly doesn't understand that Josh might be busy. That is when she takes matters into her own hands…or paws, or in this case, teeth. No, she doesn't bite Josh. She would never do that, but she will use her teeth to pull off Josh's sock and nibble on his toes. Now nibbling on someone's toes is…well, eeeewwww, but Molly just doesn't care what we think. If it will get Josh's attention, she will do whatever it takes. I guess it is a way of telling Josh exactly how she feels, but I still think it is gross.
Josh and Molly are practically inseparable. There is no doubt that Molly is Josh's best friend…at least in the animal world, and he is hers. If it were possible, they would never be apart. It's funny how animals have a certain member of the family that is their favorite, and the animal seems to thinks that the human is the pet. It is a show of love and dedication that you don't get anywhere else. It is why we have pets I guess. Unconditional love and devotion to another being, whether it is man or animal is something very special.


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Home > All Cities > Loganville, GA Real Estate Listings > Breckenridge Club Subdivision
Properties for sale in the Breckenridge Club Subdivision, Loganville, GA
Properties 1 to 1 of 1
656 Stonecrest Dr, Loganville, GAList Price: $172,000 | Bed:3 | Bath:2.00
This lovely ranch is located in the quiet Breckinridge Subdivision. it has 3 bedrooms and 2 bathrooms, garden style tub, nicely sized kitchen with breakfast area, 2 car garage, front porch and MORE. Property Sold "AS IS" w/ No disclosures from Seller. We are entertaining all offers. Home is currently occupied . CALL NOW for details. Level Lot 0 Cable In Street, Wall-to-wall Carpet, Double Vanity, Garden Tub, Walk-in Closet Clubhouse, Playground, Pool, Sidewalks, Street Lights, Tennis Courts, Underground Utilities, Neighborhood Association, None None Deck/Patio, Fenced Yard, Porch
Listing Office: MAXIMUM ONE GRT. ATL. REALTOR | MLS ID#: 07600227


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Built DSM vs. 408 Trans Am
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555whp 04 Cobra vs. 1g Talon
My 2004 Ford Mustang Cobra vs. Bryans 1992 Eagle Talon TSi FWD. Cobra has an FRPP Aluminator motor, Whipple Supercharger, and support, and the Talon has a built motor and trapped 133mph.


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Novels to watch
The novel takes to the stage and comes to life in a series of pièces
Whatever one's opinions, the novel remains the most
effective way to spread ideas and information. On top of
being the most intriguing and refined form of entertainment. And
now it takes to the stage in a mix of action and
The great Neapolitan, Erri De Luca, has written and stars in In viaggio con Aurora ("Travelling with Aurora") (promomusic. it), a hypnotic, erudite voyage through the 20th century.
Terra padre ("Father Earth") (archivolto.it), directed by Giorgio Gallione and written by Roberto Saviano, instead stars Neri Marcorè alongside Eugenio Allegri, and is set in the present day.
Le signorine di Wilko ("Wilko's ladies") by Jaroslaw Iwaszkiewicz, one of the most important writers on the Polish scene today, is set in the 1930s; the text has been staged by the Latvian Alvis Hermanis, one of the most innovative directors in Europe today.
Zoraide Cremonini, Vogue Italia, November 2010 (no. 723), p. 48
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Vittoria Mentasti - Dead Sea
Vittoria Mentasti's Dead Sea takes us to a place where the sky and the sea are one
Kristin Prim and The Provocateur's letters
A chat with Kristin Prim, the founder of The Provocateur, the site that publishes letters written expressely by leading women addressing the whole female world. Vogue.it presents you an exclusive preview of the letter written by Dresden Dolls' Amanda Palmer
Fashion shows are changing: Burberry and all that's new on the runways
Menswear and womenswear collections will walk together and will be on sale right after the show. These are the news from Burberry but the evolution is generalized: runway shows are changing


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The Power Lunch Series is a new program this fall for students in the Coggin College of Business. Each month, an accomplished professional will be invited to informally discuss a topic of their choice with a small group of students. The event will take place in a casual setting to encourage dialogue and meaningful interactions. Lunch is provided at no charge to all participants. Seats are limited, RSVP in Career Wings is required.
24th | 12:00PM - 1:00PM | Event ID: 625
Kirk Williams/President & CEO of Proficient Auto Transport
Kirk Williams is the President & CEO of Proficient
Auto Transport. Kirk has an extensive background in the field of logistics. Proficient
Auto Transport is a premier Florida auto transport company, and one of the
leading auto transport companies anywhere. Specializing in new import and luxury
car transport, their passion for flawless on-time execution, zero damage, and
absolute reliability has empowered them to become one of the world's elite car
transport services.
22nd | 12:00PM - 1:00PM | Event ID: 626
Rick Moyer/Managing Partner PwC
Mr. Moyer currently
serves as the Jacksonville, FL Managing Partner and as a National Banking
Partner. He has been servicing firms of varying size and complexity in the
banking and private equity sectors for over twelve years. Rick has worked across a broad
range of complex areas in the banking industry including; Enterprise Risk
Management, Interpretation and Application of Accounting Standards, Pricing and
Integration of Acquisitions, Internal Audit Strategy, Financial Reserve
Analysis, Vendor Oversight and Asset Valuation.
27th | 12:00PM - 1:00PM | Event ID: 627
Elaine Johnson/Sr. Director, HR Business Development at Florida Blue
October's guest is Elaine Johnson, Sr. Director of HR
Business Development at Florida Blue. Elaine has an extensive background in
both HR and business strategy/business development.
19th | 12:00PM - 1:00PM | Event ID: 628
Jim Prohaska/Partner and Business Director with Florachem
November's guest is Jim Prohaska, Partner and Business
Director at Florachem Corporation. Jim has an extensive background in the
sourcing, marketing and technology of Pine Chemicals and Citrus Products
derivatives with significant experience in China, India, Brazil and Mexico-view
his profile on LinkedIn for details.
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Someday, Ferrari 599 GTO. Someday.
[Maybe more than anything else, the Ferrari 599 looks weird. How do all these shadows and lines fold in on each other? Photo Credit: Ferrari]
You've heard a lot of ranting about how a three-pedal stick shift could become some kind of expensive, exclusive feature rather than a maligned and dying standard transmission. Here's some proof.
Driving a Ferrari 599 lets everyone know how much money you make. Covering your Ferrari 599 in velvet, however, lets everyone know that you make so much money you are no longer restricted by the bounds of taste and civility.
Remember when Chris Harris wrote his tell-all screed outlining precisely How Ferrari Spins? Well, he wanted access to a Ferrari again, so he did what any other Maranello-blackballed auto journo with a well-managed awesome-car fund might do: He bought a 599.
Without all its electronic minders, the Ferrari 599 is an absolute monster. It is also the last big Ferrari to come with a manual. Would you teach your daughter (or son) how to drive stick on a 612 horsepower GT?
If you're an affluent car enthusiast who has always desired a vintage Volvo station wagon that has no problem embarrassing a new Ferrari in a straight line (who hasn't), you're in luck. The car you see here, which may be the only one in the world that fits this description, is currently for sale.
A Jalopnik reader caught this Ferrari 599 crashed off the road near Jacksonville, Florida. Apparently 612 horsepower and rear-wheel-drive are a bit of a handful in the rain. Who knew?
When they aren't setting themselves on fire, it appears another one of the Ferrari 599's favorite past times is terrifying children. What sounds like the glorious wail of the 599 GTO's 670 horsepower six liter V12 to us appears to be only one thing to the kid taking a look at it—very very loud. [Brief NSFW language]
A six-cylinder, six-liter bespoke Ferrari concept? Sounds like someone didn't proofread the press release that came out of Villa d'Este sponsor BMW earlier today. Not that we wouldn't love to see what a big-bore six in a Ferrari would be like.
Amazing video from Tunisia shows ousted Tunisian president Ben Ali's Ferrari being taken away from his compound using a giant forklift. They couldn't find the keys?
I'm all for driving your expensive 599 GTO instead of letting it languish and rot under a cover, but there are probably times you should park it in a garage. More at SWNS. (Photo: Peter Watt)
Good morning Fiorano! A FerrariChat member caught what looks to be Ferrari's 599 GTB Fiorano update being flogged on, you guessed it, the Fiorano test track. Is it the next 599, or the first look at the upcoming 599 hybrid?
A Ferrari 599 owner in Australia drifted into oncoming traffic and hit two motorcyclists head-on in October. One rider was in a coma for two weeks and suffered a broken back and hip. The Ferrari owner? Back on the road.
This is the Ferrari 599 SA Aperta, the drop-top roadster version of the 599. Want one? Tough. Even before it makes its public debut next week in Paris, Ferrari's already sold every one of them.
With news that Ferrari held a special gathering for extra-special owners at Pebble Beach to show off the Ferrari 599 roadster slowly leaking out, we tapped our top Ferrari source (guess who!) to find out if it's true. It is.
It's embarrassing when your friends all have trains and all you can afford is a pathetic gold-plated Ferrari. That's what fathers are for. [reddit]
The Ferrari 599XX claims to have just became the first production-derived sports car to break the seven-minute barrier at the Nurburgring, lapping it at an astonishing 6:58.16. But is it really a record?
Halfway between the Ferrari 599 GTB Fiorano and the track-only Ferrari 599XX is Maranello's latest prancing stallion — the Ferrari 599 GTO. It not only looks epic, it's got the stats and pedigree to match the aggressive design.
Nevermind from-afar spy photos, here's the Ferrari 599 GTO completely in the nude. With a presumed 680 HP and lower weight it's not just Italy's worst kept secret, it's the hottest prancing horse since the Enzo. One more picture below.


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Practicing regularly is key to learning how to play the guitar the best you can. [ ... ]
Topsy-turvy wonderful life
February 11, 2008
by carey
I haven't updated this blog for ages already. And that's stating the obvious! For the few visitors dropping by every now and then, thanks for the visit and sorry for not writing anything for more than a month. Life's been wonderfully hectic and topsy-turvy but I'm enjoying it. Here's to…


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He is......the logo of NUFFNANG! XD
Looks familiar to you, isn't it?
Ok, now now, let's back to the original topic that I am going to talk about which is.....
"how you think the famous Nuffnang stick man should celebrate his 5th birthday."
People get to see hot guys in swimming trunks and hot girls in Bikinis.
Oh yeah? =P
Let's get drunk and dance the night away!
*Holding stickman's hands and dancing happily*
Invite friends, neighbour, families to have a birthday gathering.
Maybe we are able to meet stickman mama, stickman papa, stickman sis, stickman bro and etc? =D
Experience more new stuff and widen up circle. =D
Stickman could be a WISE and SMART stickman!
Food is to enjoy, not to suffer. =P
According to scientific investigation, stickman should eat more in order to grow fatter as TRUNKMAN a.k.a. TREE TRUNKMAN. =P
Who knows maybe the natural instinct of this stickman is a singer? =P


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Hi Betsy-
Being completely annoyed with my job right now, I was looking around at
other options (not seriously- but more curious)- so anyway there is a job in
Ft Collins Colorado. Can you tell me what is it like there? (climate, cost
of living, sociopolitical climate?)
Sac, CA
-----Original Message-----
From: email@example.com [mailto:firstname.lastname@example.com]On
Behalf Of Betsy Kelson
Sent: Thursday, May 20, 2004 7:45 AM
To: email@example.com
Subject: Re: [CHAT] tornadoes in Colorado
Hi all!
I am alive and well and did not get a(e)ffected by twirlies. From the
Garden Center I can watch the thunder heads build up and slide to the
east...knowing that something is going to get clobbered.
The Garden Center is situated about two miles from the beginning of the
foothills so twirlies are rare...but we will often get hail which is not
good for the plants. It really makes me laugh inside when a customer brings
me holey or shreaded leaves and wants to purchase a spray to kill the inscet
that is doing it. When I tell them that it is hail damage, oftren time their
response is " But it did not hail at my house" The perp has melted away
by the time they get home of course.
I am having a day off today...yipee AND its not snowing or raining. I am
3 for 4 on bad days off. Ended up doing housework.
I have squeezed in the planting of the cool season crops and have one
tomato under the Wall O' Water. Poor tomato thing got snowed under last
thursday and the WoW keep it from dying.
Happy Gardening!!
----- Original Message -----
From: <firstname.lastname@example.com>
To: <email@example.com>
Sent: Tuesday, May 11, 2004 4:20 PM
Subject: [CHAT] tornadoes in Colorado
> Just flipped on the weather and heard about tornadoes in CO.
> girl
> - you with us?? Everything OK up there?
> Pam Evans
> Kemp, TX
> zone 8A
> ---------------------------------------------------------------------
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Pusha T – Wrath of Caine (Mixtape)
Tracklist and download link after the jump.
Download: Livemixtapes | Datpiff | Alternate
Tracklist and download link after the jump.
Download: Livemixtapes | Datpiff | Alternate
There's been another royal sighting in San Diego County!
Britain's Prince Harry spent Saturday night at the Belly Up Tavern in Solana Beach with a dozen friends, enjoying the music and dancing with delighted young ladies.
"He was a real dude," Matt Burke, lead singer for Vokab Kompany, told People magazine. "He wasn't putting on airs and acting like a prince. Just to think he's down with that scene is super-tight."
Translation: The unmarried 27-year-old prince was well-behaved and appeared appreciative of the music.
He had only one rule: No pictures, please.
LA Times article from 2011
In case niggas still think they are lies in my verses.
Jimmy Butler>>>>>>>>>
Shout out to Noah with the double-double
Man I couldn't imagine waking up and remembering I'm addicted to heroin
If that's a true story, more power to you
That shit done murked a lotta lives and dreams
No troll…I had my vices….the lord saved me…I found god…
Crack was never my cup of tea…dealers around here used to put rat poison in it…a fiend was left slumped over for trying it…
I'm back on my feet…I talk to the youth now….i purchased veneers…
My life is real
You nahrighters is smart…none of you are street or been in the streets…
You 9-5, office pool, cubicle working niggas that went to college…
I was in the sktreets….the skreets fucked me up…
Man Future's hook on Ring Ring on the Rich Forever mixtape >>>>
My niggas used to get mad and laugh at me cause I played that shit so much like
Also sorry for all the grammatical and spelling errors today I don't know what's up with me
I aint bout that junkie life
From what I seen…
Shits stressful
I talk to the black urban youth….
I tell em work on they jumpshot….
Keep they nose in them books…
Stay off the skreets…nothing good there…
They relate more to me….than some honkey cracka trust fund baby tryna teach em….
I tell the youngins stay in sports and school…
Stay off the corners, blocks….
No troll…I had my vices….the lord saved me…I found god…
Nosign hard drugs
Ross been trending for 2 days straight, he might go diamond


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Adds a ticker bar to your wordpress site which will show your recent post headlines.
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This plugin adds a ticker which shows recent posts as headlines. You can set the position top or bottom, fixed or absolute or set the number of posts to show. Some pretty neat features yet to come.
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A new method for multinomial inference using Dempster-Shafer...
Office of Scientific and Technical Information (OSTI)
A new method for multinomial inference is proposed by representing the cell probabilities as unordered segments on the unit interval and following Dempster-Shafer (DS) theory. The ...
A Plug-in Hybrid Consumer Choice Model with Detailed Market Segmentation
Lin, Zhenhong; Greene, David L
This paper describes a consumer choice model for projecting U.S. demand for plug-in hybrid electric vehicles (PHEV) in competition among 13 light-duty vehicle technologies over the period 2005-2050. New car buyers are disaggregated by region, residential area, attitude toward technology risk, vehicle usage intensity, home parking and work recharging. The nested multinomial logit (NMNL) model of vehicle choice incorporates daily vehicle usage distributions, refueling and recharging availability, technology learning by doing, and diversity of choice among makes and models. Illustrative results are presented for a Base Case, calibrated to the Annual Energy Outlook (AEO) 2009 Reference Updated Case, and an optimistic technology scenario reflecting achievement of U.S. Department of Energy s (DOE s) FreedomCAR goals. PHEV market success is highly dependent on the degree of technological progress assumed. PHEV sales reach one million in 2037 in the Base Case but in 2020 in the FreedomCARGoals Case. In the FreedomCARGoals Case, PHEV cumulative sales reach 1.5 million by 2015. Together with efficiency improvements in other technologies, petroleum use in 2050 is reduced by about 45% from the 2005 level. After technological progress, PHEV s market success appears to be most sensitive to recharging availability, consumers attitudes toward novel echnologies, and vehicle usage intensity. Successful market penetration of PHEVs helps bring down battery costs for electric vehicles (EVs), resulting in a significant EV market share after 2040.
A new method for multinomial inference using Dempster-Shafer...
Office of Scientific and Technical Information (OSTI)
The resulting DS posterior is then strengthened to improve symmetry and learning ... Publication: United States Language: English Subject: 97; DISTRIBUTION; LEARNING; SYMMETRY
Predicting primary crystalline phase and liquidus temperature above or below 1050{degrees}C as functions of glass composition
Redgate, P.E.; Piepel, G.F.
This report presents the results of applying statistical empirical modeling techniques to primary crystalline phase at the liquidus temperature (T{sub L}) and (ii) whether liquidus temperature is above or below 1050{degree}C (1OO{degree}C below a melting temperature of 1150{degree}C). Data used in modeling primary crystalline phase and liquidus temperate are from the Composition Variability Study (CVS) of Hanford waste glass compositions and properties. The majority of the 123 CVS glasses are categorized into one of 13 primary crystalline phases (at the liquidus temperature). They are also classified as to having T{sub L} Above or Below 1050{degree}C. Two common statistical methods used to model such categorical data are the multinomial logit and classification tree models. The classification tree models provided an overall better modeling approach than did the multinomial logit models. The performance of models in this report should be compared to the performance of the revised ``Development of Models and Software for Liquidus Temperature of Glasses of HWVP Products`` models from Ecole Polytechnique. If the Ecole Polytechnique models perform better than the models discussed in this report, no additional effort on these models would be needed. However, if the converse is true, it may be worthwhile to invest additional effort on statistical empirical modeling methods.
ADOPT: A Historically Validated Light Duty Vehicle Consumer Choice Model
Brooker, A.; Gonder, J.; Lopp, S.; Ward, J.
The Automotive Deployment Option Projection Tool (ADOPT) is a light-duty vehicle consumer choice and stock model supported by the U.S. Department of Energy's Vehicle Technologies Office. It estimates technology improvement impacts on U.S. light-duty vehicles sales, petroleum use, and greenhouse gas emissions. ADOPT uses techniques from the multinomial logit method and the mixed logit method estimate sales. Specifically, it estimates sales based on the weighted value of key attributes including vehicle price, fuel cost, acceleration, range and usable volume. The average importance of several attributes changes nonlinearly across its range and changes with income. For several attributes, a distribution of importance around the average value is used to represent consumer heterogeneity. The majority of existing vehicle makes, models, and trims are included to fully represent the market. The Corporate Average Fuel Economy regulations are enforced. The sales feed into the ADOPT stock model. It captures key aspects for summing petroleum use and greenhouse gas emissions This includes capturing the change in vehicle miles traveled by vehicle age, the creation of new model options based on the success of existing vehicles, new vehicle option introduction rate limits, and survival rates by vehicle age. ADOPT has been extensively validated with historical sales data. It matches in key dimensions including sales by fuel economy, acceleration, price, vehicle size class, and powertrain across multiple years. A graphical user interface provides easy and efficient use. It manages the inputs, simulation, and results.
Occupant Perceptions and a Health Outcome in Retail Stores
Zhao, Mingjie; Kim, Yang-Seon; Srebric, Jelena
Indoor Environmental Quality (IEQ) in commercial buildings, such as retail stores, can affect employee satisfaction, productivity, and health. This study administered an IEQ survey to retail employees and found correlations between measured IEQ parameters and the survey responses. The survey included 611 employees in 14 retail stores located in Pennsylvania (climate zone 5A) and Texas (climate zone 2A). The survey questionnaire featured ratings of different aspects of IEQ, including thermal comfort, lighting and noise level, indoor smells, overall cleanness, and environmental quality. Simultaneously with the survey, on-site physical measurements were taken to collect data of relative humidity levels, air exchange rates, dry bulb temperatures, and contaminant concentrations. This data was analyzed using multinomial logit regression with independent variables being the measured IEQ parameters, employees' gender, and age. This study found that employee perception of stuffy smells is related to formaldehyde and PM10 concentrations. Furthermore, the survey also asked the employees to report an annual frequency of common colds as a health indicator. The regression analysis showed that the cold frequency statistically correlates with the measured air exchange rates, outdoor temperatures, and indoor PM concentrations. Overall, the air exchange rate is the most influential parameter on the employee perception of the overall environmental quality and self-reported health outcome.
Discrete Choice Analysis: Hydrogen FCV Demand Potential
Office of Energy Efficiency and Renewable Energy (EERE) (indexed site)
* NREL used BIOGEME* for parameter estimation, model development (logit, nested ... Trips: No Adv Planning Driving Radius Price Difference Fuel Cost Difference Possible Long ...
Bootstrapping a Sustainable North American PEM Fuel Cell Industry...
Office of Energy Efficiency and Renewable Energy (EERE) (indexed site)
a Sustainable North American PEM Fuel Cell Industry: Could a Federal Acquisition ... for Fully Installed Fuel Cell Systems ......19 8 Logit ...
Comparative Evaluation of Two Methods to Estimate Natural Gas Production in Texas
This report describes an evaluation conducted by the Energy Information Administration (EIA) in August 2003 of two methods that estimate natural gas production in Texas. The first method (parametric method) was used by EIA from February through August 2003 and the second method (multinomial method) replaced it starting in September 2003, based on the results of this evaluation.
Modeling patterns in count data using loglinear and related models
Atwood, C.L.
This report explains the use of loglinear and logit models, for analyzing Poisson and binomial counts in the presence of explanatory variables. The explanatory variables may be unordered categorical variables or numerical variables, or both. The report shows how to construct models to fit data, and how to test whether a model is too simple or too complex. The appropriateness of the methods with small data sets is discussed. Several example analyses, using the SAS computer package, illustrate the methods.
Liu, Changzheng; Greene, David L
How demand for E85 might evolve in the future in response to changing economics and policies is an important subject to include in the National Energy Modeling System (NEMS). This report summarizes a study to develop an E85 choice model for NEMS. Using the most recent data from the states of Minnesota, North Dakota, and Iowa, this study estimates a logit model that represents E85 choice as a function of prices of E10 and E85, as well as fuel availability of E85 relative to gasoline. Using more recent data than previous studies allows a better estimation of non-fleet demand and indicates that the price elasticity of E85 choice appears to be higher than previously estimated. Based on the results of the econometric analysis, a model for projecting E85 demand at the regional level is specified. In testing, the model produced plausible predictions of US E85 demand to 2040.
An Evaluation of Parametric and Nonparametric Models of Fish Population Response.
Haas, Timothy C.; Peterson, James T.; Lee, Danny C.
Predicting the distribution or status of animal populations at large scales often requires the use of broad-scale information describing landforms, climate, vegetation, etc. These data, however, often consist of mixtures of continuous and categorical covariates and nonmultiplicative interactions among covariates, complicating statistical analyses. Using data from the interior Columbia River Basin, USA, we compared four methods for predicting the distribution of seven salmonid taxa using landscape information. Subwatersheds (mean size, 7800 ha) were characterized using a set of 12 covariates describing physiography, vegetation, and current land-use. The techniques included generalized logit modeling, classification trees, a nearest neighbor technique, and a modular neural network. We evaluated model performance using out-of-sample prediction accuracy via leave-one-out cross-validation and introduce a computer-intensive Monte Carlo hypothesis testing approach for examining the statistical significance of landscape covariates with the non-parametric methods. We found the modular neural network and the nearest-neighbor techniques to be the most accurate, but were difficult to summarize in ways that provided ecological insight. The modular neural network also required the most extensive computer resources for model fitting and hypothesis testing. The generalized logit models were readily interpretable, but were the least accurate, possibly due to nonlinear relationships and nonmultiplicative interactions among covariates. Substantial overlap among the statistically significant (P<0.05) covariates for each method suggested that each is capable of detecting similar relationships between responses and covariates. Consequently, we believe that employing one or more methods may provide greater biological insight without sacrificing prediction accuracy.
Comparison of Oncentra® Brachy IPSA and graphical optimisation techniques: a case study of HDR brachytherapy head and neck and prostate plans
Jameson, Michael G; Ohanessian, Lucy; Batumalai, Vikneswary; Patel, Virendra; Holloway, Lois C
There are a number of different dwell positions and time optimisation options available in the Oncentra® Brachy (Elekta Brachytherapy Solutions, Veenendaal, The Netherlands) brachytherapy treatment planning system. The purpose of this case study was to compare graphical (GRO) and inverse planning by simulated annealing (IPSA) optimisation techniques for interstitial head and neck (HN) and prostate plans considering dosimetry, modelled radiobiology outcome and planning time. Four retrospective brachytherapy patients were chosen for this study, two recurrent HN and two prostatic boosts. Manual GRO and IPSA plans were generated for each patient. Plans were compared using dose–volume histograms (DVH) and dose coverage metrics including; conformity index (CI), homogeneity index (HI) and conformity number (CN). Logit and relative seriality models were used to calculate tumour control probability (TCP) and normal tissue complication probability (NTCP). Approximate planning time was also recorded. There was no significant difference between GRO and IPSA in terms of dose metrics with mean CI of 1.30 and 1.57 (P > 0.05) respectively. IPSA achieved an average HN TCP of 0.32 versus 0.12 for GRO while for prostate there was no significant difference. Mean GRO planning times were greater than 75 min while average IPSA planning times were less than 10 min. Planning times for IPSA were greatly reduced compared to GRO and plans were dosimetrically similar. For this reason, IPSA makes for a useful planning tool in HN and prostate brachytherapy.
Assessment Of Carbon Leakage In Multiple Carbon-Sink Projects: ACase Study In Jambi Province, Indonesia
Boer, Rizaldi; Wasrin, Upik R.; Hendri, Perdinan; Dasanto,Bambang D.; Makundi, Willy; Hero, Julius; Ridwan, M.; Masripatin, Nur
Rehabilitation of degraded forest land throughimplementation of carbon sink projects can increase terrestrial carbonstock. However, carbon emissions outside the project boundary, which iscommonly referred to as leakage, may reduce or negate the sequestrationbenefits. This study assessed leakage from carbon sink projects thatcould potentially be implemented in the study area comprised of elevensub-districts in the Batanghari District, Jambi Province, Sumatra,Indonesia. The study estimates the probability of a given land use/coverbeing converted into other uses/cover, by applying a logit model. Thepredictor variables were: proximity to the center of the land use area,distance to transportation channel (road or river), area of agriculturalland, unemployment (number of job seekers), job opportunities, populationdensity and income. Leakage was estimated by analyzing with and withoutcarbon sink projects scenarios. Most of the predictors were estimated asbeing significant in their contribution to land use cover change. Theresults of the analysis show that leakage in the study area can be largeenough to more than offset the project's carbon sequestration benefitsduring the period 2002-2012. However, leakage results are very sensitiveto changes of carbon density of the land uses in the study area. Byreducing C-density of lowland and hill forest by about 10 percent for thebaseline scenario, the leakage becomes positive. Further data collectionand refinement is therefore required. Nevertheless, this study hasdemonstrated that regional analysis is a useful approach to assessleakage.
Electric and hybrid electric vehicles: A technology assessment based on a two-stage Delphi study
Vyas, A.D.; Ng, H.K.; Santini, D.J.; Anderson, J.L.
To address the uncertainty regarding future costs and operating attributes of electric and hybrid electric vehicles, a two stage, worldwide Delphi study was conducted. Expert opinions on vehicle attributes, current state of the technology, possible advancements, costs, and market penetration potential were sought for the years 2000, 2010, and 2020. Opinions related to such critical components as batteries, electric drive systems, and hybrid vehicle engines, as well as their respective technical and economic viabilities, were also obtained. This report contains descriptions of the survey methodology, analytical approach, and results of the analysis of survey data, together with a summary of other factors that will influence the degree of market success of electric and hybrid electric vehicle technologies. Responses by industry participants, the largest fraction among all the participating groups, are compared with the overall responses. An evaluation of changes between the two Delphi stages is also summarized. An analysis of battery replacement costs for various types is summarized, and variable operating costs for electric and hybrid vehicles are compared with those of conventional vehicles. A market penetration analysis is summarized, in which projected market shares from the survey are compared with predictions of shares on the basis of two market share projection models that use the cost and physical attributes provided by the survey. Finally, projections of market shares beyond the year 2020 are developed by use of constrained logit models of market shares, statistically fitted to the survey data.
Targeted chlorination for biofouling control in steam electric power plant condenser tubes
Tewari, R.N.
The objective of this study was to develop an understanding of the relationships between biofouling, heat transfer, and to assess the technical feasibility of the targeted chlorination (TC) concept as an alternative to conventional chlorination in once-through seawater cooling systems. A shell and tube type heat exchanger was designed and constructed. The test facility monitored biofouling growth by measuring heat transfer resistance (thermal performance), pressure drop (hydraulic performance), and biomass deposit. Biocide effectiveness was determined by triplicates average residual biomass. Tests were run to evaluate 18 treatment scenarios. Preliminary tests were done to determine variabilities between shells and among tubes, effect of heating, very high dose chlorine burn out and regrowth behavior. LOGIT, a software package by the National Bureau of Standards (NBS) for sigmoidal fit, was used for the preliminary test data. The other three tests studied effect of chlorine dosage (low, high), contact time, and frequency. To minimize variability in results, triplicates for each chlorination scheme were used. The total amount of chlorine applied (flow rate Q x C x T x F) ranged from about 400 to 4,000 pounds per million gallons per day (an equivalent to a CTF range of 6 to 60 ppm.min/day). With respect to efficiency of biofouling control, it was found by regression analysis that among four variables C, T, (CT) and F, F was most significant and C, T, and (CT) were relatively equal in ranking.
Allelic variation contributes to bacterial host specificity
Yue, Min; Han, Xiangan; Masi, Leon De; Zhu, Chunhong; Ma, Xun; Zhang, Junjie; Wu, Renwei; Schmieder, Robert; Kaushik, Radhey S.; Fraser, George P.; et al
Understanding the molecular parameters that regulate cross-species transmission and host adaptation of potential pathogens is crucial to control emerging infectious disease. Although microbial pathotype diversity is conventionally associated with gene gain or loss, the role of pathoadaptive nonsynonymous single-nucleotide polymorphisms (nsSNPs) has not been systematically evaluated. Here, our genome-wide analysis of core genes within Salmonella enterica serovar Typhimurium genomes reveals a high degree of allelic variation in surface-exposed molecules, including adhesins that promote host colonization. Subsequent multinomial logistic regression, MultiPhen and Random Forest analyses of known/suspected adhesins from 580 independent Typhimurium isolates identifies distinct host-specific nsSNP signatures. Moreover, population andmore » functional analyses of host-associated nsSNPs for FimH, the type 1 fimbrial adhesin, highlights the role of key allelic residues in host-specific adherence in vitro. In conclusion, together, our data provide the first concrete evidence that functional differences between allelic variants of bacterial proteins likely contribute to pathoadaption to diverse hosts.« less
Allelic variation contributes to bacterial host specificity
Yue, Min; Han, Xiangan; Masi, Leon De; Zhu, Chunhong; Ma, Xun; Zhang, Junjie; Wu, Renwei; Schmieder, Robert; Kaushik, Radhey S.; Fraser, George P.; Zhao, Shaohua; McDermott, Patrick F.; Weill, François-Xavier; Mainil, Jacques G.; Arze, Cesar; Fricke, W. Florian; Edwards, Robert A.; Brisson, Dustin; Zhang, Nancy R.; Rankin, Shelley C.; Schifferli, Dieter M.
Understanding the molecular parameters that regulate cross-species transmission and host adaptation of potential pathogens is crucial to control emerging infectious disease. Although microbial pathotype diversity is conventionally associated with gene gain or loss, the role of pathoadaptive nonsynonymous single-nucleotide polymorphisms (nsSNPs) has not been systematically evaluated. Here, our genome-wide analysis of core genes within Salmonella enterica serovar Typhimurium genomes reveals a high degree of allelic variation in surface-exposed molecules, including adhesins that promote host colonization. Subsequent multinomial logistic regression, MultiPhen and Random Forest analyses of known/suspected adhesins from 580 independent Typhimurium isolates identifies distinct host-specific nsSNP signatures. Moreover, population and functional analyses of host-associated nsSNPs for FimH, the type 1 fimbrial adhesin, highlights the role of key allelic residues in host-specific adherence in vitro. In conclusion, together, our data provide the first concrete evidence that functional differences between allelic variants of bacterial proteins likely contribute to pathoadaption to diverse hosts.
Attitude towards the incorporation of the selective collection of biowaste in a municipal solid waste management system. A case study
Bernad-Beltrán, D.
Highlights: • Attitude towards incorporating biowaste selective collection is analysed. • Willingness to participate and to pay in biowaste selective collection is obtained. • Socioeconomic aspects affecting WtParticipate and WtPay are identified. - Abstract: European waste legislation has been encouraging for years the incorporation of selective collection systems for the biowaste fraction. European countries are therefore incorporating it into their current municipal solid waste management (MSWM) systems. However, this incorporation involves changes in the current waste management habits of households. In this paper, the attitude of the public towards the incorporation of selective collection of biowaste into an existing MSWM system in a Spanish municipality is analysed. A semi-structured telephone interview was used to obtain information regarding aspects such as: level of participation in current waste collection systems, willingness to participate in selective collection of biowaste, reasons and barriers that affect participation, willingness to pay for the incorporation of the selective collection of biowaste and the socioeconomic characteristics of citizens who are willing to participate and pay for selective collection of biowaste. The results showed that approximately 81% of the respondents were willing to participate in selective collection of biowaste. This percentage would increase until 89% if the Town Council provided specific waste bins and bags, since the main barrier to participate in the new selective collection system is the need to use specific waste bin and bags for the separation of biowaste. A logit response model was applied to estimate the average willingness to pay, obtaining an estimated mean of 7.5% on top of the current waste management annual tax. The relationship of willingness to participate and willingness to pay for the implementation of this new selective collection with the socioeconomic variables (age, gender, size of the
Single-Fraction Versus 5-Fraction Radiation Therapy for Metastatic Epidural Spinal Cord Compression in Patients With Limited Survival Prognoses: Results of a Matched-Pair Analysis
Rades, Dirk; Huttenlocher, Stefan; Šegedin, Barbara; Perpar, Ana; Conde, Antonio J.; Garcia, Raquel; Veninga, Theo; Stalpers, Lukas J.A.; Cacicedo, Jon; Rudat, Volker; Schild, Steven E.
Purpose: This study compared single-fraction to multi-fraction short-course radiation therapy (RT) for symptomatic metastatic epidural spinal cord compression (MESCC) in patients with limited survival prognosis. Methods and Materials: A total of 121 patients who received 8 Gy × 1 fraction were matched (1:1) to 121 patients treated with 4 Gy × 5 fractions for 10 factors including age, sex, performance status, primary tumor type, number of involved vertebrae, other bone metastases, visceral metastases, interval between tumor diagnosis and MESCC, pre-RT ambulatory status, and time developing motor deficits prior to RT. Endpoints included in-field repeated RT (reRT) for MESCC, overall survival (OS), and impact of RT on motor function. Univariate analyses were performed with the Kaplan-Meier method and log-rank test for in-field reRT for MESCC and OS and with the ordered-logit model for effect of RT on motor function. Results: Doses of 8 Gy × 1 fraction and 4 Gy × 5 fractions were not significantly different with respect to the need for in-field reRT for MESCC (P=.11) at 6 months (18% vs 9%, respectively) and 12 months (30% vs 22%, respectively). The RT regimen also had no significant impact on OS (P=.65) and post-RT motor function (P=.21). OS rates at 6 and 12 months were 24% and 9%, respectively, after 8 Gy × 1 fraction versus 25% and 13%, respectively, after 4 Gy × 5 fractions. Improvement of motor function was observed in 17% of patients after 8 Gy × 1 fraction and 23% after 4 Gy × 5 fractions, respectively. Conclusions: There were no significant differences with respect to need for in-field reRT for MESCC, OS, and motor function by dose fractionation regimen. Thus, 8 Gy × 1 fraction may be a reasonable option for patients with survival prognosis of a few months.
WE-D-BRE-02: BEST IN PHYSICS (THERAPY) - Radiogenomic Modeling of Normal Tissue Toxicities in Prostate Cancer Patients Receiving Hypofractionated Radiotherapy
Coates, J; Jeyaseelan, K; Ybarra, N; David, M; Faria, S; Souhami, L; Cury, F; Duclos, M; Naqa, I El
Purpose: It has been realized that inter-patient radiation sensitivity variability is a multifactorial process involving dosimetric, clinical, and genetic factors. Therefore, we explore a new framework to integrate physical, clinical, and biological data denoted as radiogenomic modeling. In demonstrating the feasibility of this work, we investigate the association of genetic variants (copy number variations [CNVs] and single nucleotide polymorphisms [SNPs]) with radiation induced rectal bleeding (RB) and erectile dysfunction (ED) while taking into account dosimetric and clinical variables in prostate cancer patients treated with curative irradiation. Methods: A cohort of 62 prostate cancer patients who underwent hypofractionated radiotherapy (66 Gy in 22 fractions) was retrospectively genotyped for CNV and SNP rs25489 in the xrcc1 DNA repair gene. Dosevolume metrics were extracted from treatment plans of 54 patients who had complete dosimetric profiles. Treatment outcomes were considered to be a Result of functional mapping of radiogenomic input variables according to a logit transformation. Model orders were estimated using resampling by leave-one out cross-validation (LOO-CV). Radiogenomic model performance was evaluated using area under the ROC curve (AUC) and LOO-CV. For continuous univariate dosimetric and clinical variables, Spearmans rank coefficients were calculated and p-values reported accordingly. In the case of binary variables, Chi-squared statistics and contingency table calculations were used. Results: Ten patients were found to have three copies of xrcc1 CNV (RB: χ2=14.6 [p<0.001] and ED: χ2=4.88[p=0.0272]) and twelve had heterozygous rs25489 SNP (RB: χ2=0.278[p=0.599] and ED: χ2=0.112[p=0.732]). LOO-CV identified penile bulb D60 as the only significant QUANTEC predictor (rs=0.312 [p=0.0145]) for ED. Radiogenomic modeling yielded statistically significant, cross-validated NTCP models for RB (rs=0.243[p=0.0443], AUC=0.665) and ED (rs=0.276[p=0
Normal Tissue Complication Probability Modeling of Radiation-Induced Hypothyroidism After Head-and-Neck Radiation Therapy
Bakhshandeh, Mohsen; Hashemi, Bijan; Mahdavi, Seied Rabi Mehdi; Nikoofar, Alireza; Vasheghani, Maryam; Kazemnejad, Anoshirvan
Purpose: To determine the dose-response relationship of the thyroid for radiation-induced hypothyroidism in head-and-neck radiation therapy, according to 6 normal tissue complication probability models, and to find the best-fit parameters of the models. Methods and Materials: Sixty-five patients treated with primary or postoperative radiation therapy for various cancers in the head-and-neck region were prospectively evaluated. Patient serum samples (tri-iodothyronine, thyroxine, thyroid-stimulating hormone [TSH], free tri-iodothyronine, and free thyroxine) were measured before and at regular time intervals until 1 year after the completion of radiation therapy. Dose-volume histograms (DVHs) of the patients' thyroid gland were derived from their computed tomography (CT)-based treatment planning data. Hypothyroidism was defined as increased TSH (subclinical hypothyroidism) or increased TSH in combination with decreased free thyroxine and thyroxine (clinical hypothyroidism). Thyroid DVHs were converted to 2 Gy/fraction equivalent doses using the linear-quadratic formula with {alpha}/{beta} = 3 Gy. The evaluated models included the following: Lyman with the DVH reduced to the equivalent uniform dose (EUD), known as LEUD; Logit-EUD; mean dose; relative seriality; individual critical volume; and population critical volume models. The parameters of the models were obtained by fitting the patients' data using a maximum likelihood analysis method. The goodness of fit of the models was determined by the 2-sample Kolmogorov-Smirnov test. Ranking of the models was made according to Akaike's information criterion. Results: Twenty-nine patients (44.6%) experienced hypothyroidism. None of the models was rejected according to the evaluation of the goodness of fit. The mean dose model was ranked as the best model on the basis of its Akaike's information criterion value. The D{sub 50} estimated from the models was approximately 44 Gy. Conclusions: The implemented normal tissue
The Design and Analysis of Salmonid Tagging Studies in the Columbia Basin : Volume XVII : Effects of Ocean Covariates and Release Timing on First Ocean-Year Survival of Fall Chinook Salmon from Oregon and Washington Coastal Hatcheries.
Burgess, Caitlin; Skalski, John R.
Effects of oceanographic conditions, as well as effects of release-timing and release-size, on first ocean-year survival of subyearling fall chinook salmon were investigated by analyzing CWT release and recovery data from Oregon and Washington coastal hatcheries. Age-class strength was estimated using a multinomial probability likelihood which estimated first-year survival as a proportional hazards regression against ocean and release covariates. Weight-at-release and release-month were found to significantly effect first year survival (p < 0.05) and ocean effects were therefore estimated after adjusting for weight-at-release. Negative survival trend was modeled for sea surface temperature (SST) during 11 months of the year over the study period (1970-1992). Statistically significant negative survival trends (p < 0.05) were found for SST during April, June, November and December. Strong pairwise correlations (r > 0.6) between SST in April/June, April/November and April/December suggest the significant relationships were due to one underlying process. At higher latitudes (45{sup o} and 48{sup o}N), summer upwelling (June-August) showed positive survival trend with survival and fall (September-November) downwelling showed positive trend with survival, indicating early fall transition improved survival. At 45{sup o} and 48{sup o}, during spring, alternating survival trends with upwelling were observed between March and May, with negative trend occurring in March and May, and positive trend with survival occurring in April. In January, two distinct scenarios of improved survival were linked to upwelling conditions, indicated by (1) a significant linear model effect (p < 0.05) showing improved survival with increasing upwelling, and (2) significant bowl-shaped curvature (p < 0.05) of survival with upwelling. The interpretation of the effects is that there was (1) significantly improved survival when downwelling conditions shifted to upwelling conditions in January (i


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Staff Sgt. Freddie Goggins Jr. of Charlie Battery, 1st Battalion, 37th Field Artillery Regiment, 3rd Stryker Brigade Combat Team, 2nd Infantry Division pulls the lanyard and fires a M777 howitzer at Forward Operating Base Al Masaak, southern Afghanistan, Aug. 21. (Photo by Lt. Col. Daniel F. Bohmer)
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