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Hotels in Arbrefontaine
Hotel reservation
Hotel rooms in Arbrefontaine
There are not so many hotel rooms in Arbrefontaine, just 2, still everyone can find an offer to suit his choice. The most common offers in this city are hostels, they count 1 out of 2, and their prevalent location is central district. According to our practice, it is the most profitable to book a hotel in the east of Arbrefontaine, as it is the location of the hotels with optimal cost and quality offers along with the cheap hotels. Taking into account the small size of the city, there is no need to dwell hotel reservation on the location: the road to the city center would take less then half an hour, so one can book a hotel in any district of Arbrefontaine. The most populated with hotels district of Arbrefontaine is the center, 100% of cheap hotel rooms are concentrated here. Arbrefontaine is a truly multifaceted city, here everyone can find a hotel of his choice: a business person, a young couple or a family with little children. The view to valley and garden from the hotel room can serve as a pleasant addition to the journey. Apart from all these, hotels in Arbrefontaine offer their customers business centre, bar and restaurant/cafe. Take a look at our selection of the cheap hotel rooms in Arbrefontaine to make a well-informed choice for your reservation!
Arbrefontaine cheap hotels
Guest Houses
All cheap hotels in Arbrefontaine
Best hotels in Arbrefontaine
Hotels in Arbrefontaine are spread around the city within the distance of 0.2 kilometers, while 2 hotels are located directly in the city center. The most popular accommodations in Arbrefontaine is
Hostellerie La Maison de Maitre
located in a 0.1 kilometers from the city center.
The best hotels are here and now. Try them!
All cities in Belgium


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From Fuzzy - A Special Angel Kitty's Catster Photos[ View profile page ]
|"I have joined the Angel Team"
Your cat loves a clean toilet -- don't we all? Catster's singing Cat Lady, Sarah Donner, explains why.24
|"I have joined the Angel Team"
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subset: commoncrawl


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This is the October 20, 2013 news archive. View today's Steelers rumors and news.
Pittsburgh Steelers
Pittsburgh Steelers News and Rumors
Time to get concerned about the Ravens
ESPN.com pittsburghlive.com profootballtalk.com CNNSI.com post-gazette.com Updated Oct 20, 2013
PITTSBURGH -- It's too early to write off the Baltimore Ravens, even though this is the first time they have a losing record this late in a season in their six years under John Harbaugh. But let's be honest: Their 19-16 loss to the Pittsburgh Steelers w…Share Tweet
Steelers running game becomes clear as a BellBy Mark Kaboly, Daily NewsIf there is anything you can say about Le'Veon Bell after his first three games in the NFL, it's that he can grade himself pretty ...Share Tweet
Total Team Effort Leads Steelers To 19-16 Win Over Ravenssteelersgab.com ESPN.com profootballtalk.com post-gazette.com Oct 20, 2013Aggressive. Physical. Not afraid. The Steelers played their best game in a long time on Sunday, and while it wasn't pretty or a blowout by any means, it was a win – a big win – 19-16 over the rival Ravens. The win wasn't sealed till the final play, when…Share Tweet
Steelers notebook: Special teams come up bigBy Ralph N. Paulk, Pittsburgh Tribune-ReviewFor the most part, the Steelers' kick return teams have rarely impacted any game this season. But Antonio Brown, Felix Jones and Emmanuel Sanders gave ...Share Tweet
Watch Pittsburgh's Troy Polamalu attempt to block an extra point – just a tad earlyyahoo.com Oct 20, 2013Maybe it was just anticipation. Maybe it was just eagerness. Maybe it was just the luxurious hair. No matter what it was, Pittsburgh Steelers safety Troy Polamalu really wanted to block Baltimore's extra point attempt in the fourth quarter.There was onl…Share Tweet
Steelers play it safe with Jarvis JonesESPN.com steelersgab.com Oct 20, 2013PITTSBURGH -- Right outside linebacker Jarvis Jones will miss his first NFL game after suffering a concussion in the Steelers' 19-6 win over the Jets last Sunday. That Jones is among the seven Steelers inactives today does not necessarily mean he didn't…Share Tweet
Steelers' decision to deactivate Curtis Brown catches Ravens' attentionprofootballtalk.com Oct 20, 2013Who says the Ravens-Steelers rivalry has lost some luster? OK, it has. But that's beside the point for now. A pre-game development has added a little intrigue to the first game of this year's home-and-home clash between Pittsburgh and Baltimore. Cornerb…Share Tweet
Report: Cowboys could trade for a running backprofootballtalk.com Oct 20, 2013The trade deadline comes in only nine days. With four significant trades already happening during the 2013 season (Trent Richardson to Indy, Jon Beason to the Giants, Eugene Monroe to the Ravens, and Levi Brown to the Steelers), more could be coming. Ia…Share Tweet
AFC North notebook: Ravens missing stars Lewis, ReedBy Alan Robinson, Pittsburgh Tribune-ReviewRavens defensive end Terrell Suggs is arguably the most disruptive defensive player to oppose the Steelers in the past 30 years. Since the sack became ...Share Tweet
Collier: Heat still on despite cooler Steelers-Ravens rivalrypost-gazette.com Oct 20, 2013The teams' records aren't as gaudy as they usually are this time of year, but the Steelers figure to have their hands full once again.Share Tweet
Head-to-head: Steelers PR Antonio Brown vs. Ravens PR/KR Jacoby Jonespost-gazette.com Oct 20, 2013The Steelers hope their return game can get started, while the Ravens' might be restarted with the return of their big-play veteran.Share Tweet
Sunday Blitz: Ravens-Steelers RecapOct 20Jim Basquil and Eric Allen break down the Steelers' Week 7 win over the Ravens.
Steelers Edge RavensOct 20Shaun Suisham made a 42-yard field goal as time expired to lift the Steelers to a 19-16 win against the Ravens.
Steelers postgame press conferenceOct 20Steelers react following game with Ravens
Week 7: Baltimore Ravens vs. Pittsburgh Steelers highlightsOct 20Pittsburgh Steelers kicker Shaun Suisham kicks a game-winning field goal to give his team a 19-16 win over the Baltimore Ravens in a battle between division rivals.


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Alpinetrek expert Hannes
"This product is no longer available."
This is either an older model or we can or will no longer reorder this product from the manufacturer.
Don't give up – we have some other alternatives for you to choose from:
Hyphen-Sports - Kid's Langarmshirt 'striped Cobalt'
Attributes & features
- Suitable for:
- Design:
- Swim shirt
- Material:
- 79% polyamide; 21% elastane
- Item No.:
- 704-0549


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PROJECT SUMIWARY (See instructions): The Cellular Physiology Core provides a series of graded in vitro model systems and technologies for studying the function and regulation of transport and other membrane proteins in isolated expression systems and organized epithelia. The Core will interact with the other Cores in such a way that studies of transport proteins and interacting proteins developed either in model systems or isolated tubules may be exploited by direct measures of their function in in vitro systems that also lend themselves to further analysis by imaging. The Core technologies also are directly applicable to the study of plasma membrane proteins identified by novel model systems. To accomplish these goals, the Core will: a) provide a center for expression of transport proteins and regulatory/interacting proteins in isolated in vitro systems, which will permit direct assessment of the influence of these interactions on electrophysiologic characteristics both at the macroscopic and single channel level. These systems include Xenopus oocytes and naive cell expression systems (e.g., HEK-293 cells) and will permit direct measure of plasma membrane expression of channels and their electrophysiologic features;b) establish systems to expand the study of transport proteins and interacting proteins/pathways in organized epithelia either natively expressing the transport proteins or in model epithelia (e.g., MDCK and FRT cells) where transport protein mutations may be evaluated more fully than in single cell expression systems. These techniques will include standard voltage clamp for assessment of short-circuit current and transepithelial resistance and direct measures of tissue capacitance;c) provide methods for modulating gene expression in epithelia. Recombinant viruses will be generated to allow reconstitution of wild-type or mutated channel subunits and expression of other genes of interest. Silencing RNAs will be expressed using recombinant viruses and lipid-mediated transfer methods to permit downregulation of gene expression;and d) provide analysis of post-translational modifications of transport proteins and regulatory proteins, including phosphorylation, ubiquitination, glycosylation and palmitoylation using both biochemical and mass spectrometry approaches.
The Pittsburgh Center for Kidney Research Cellular Physiology Core provides mechanistic analyses of the functions of membrane transport and other associated proteins through a series of graded in vitro model systems. This Core interfaces with and complements the other Cores and has the overall goal of elucidating at a molecular and cellular level the function and regulation of key proteins involved in kidney diseases.
|Chang, Andy; Yeung, Steven; Thakkar, Arvind et al. (2015) Prevention of skin carcinogenesis by the ?-blocker carvedilol. Cancer Prev Res (Phila) 8:27-36
|Jackson, Edwin K; Cheng, Dongmei; Verrier, Jonathan D et al. (2014) Interactive roles of CD73 and tissue nonspecific alkaline phosphatase in the renal vascular metabolism of 5'-AMP. Am J Physiol Renal Physiol 307:F680-5
|Novitskaya, Tatiana; McDermott, Lee; Zhang, Ke Xin et al. (2014) A PTBA small molecule enhances recovery and reduces postinjury fibrosis after aristolochic acid-induced kidney injury. Am J Physiol Renal Physiol 306:F496-504
|Morrell, Eric D; Kellum, John A; Hallows, Kenneth R et al. (2014) Epithelial transport during septic acute kidney injury. Nephrol Dial Transplant 29:1312-9
|Prakasam, H Sandeep; Gallo, Luciana I; Li, Hui et al. (2014) A1 adenosine receptor-stimulated exocytosis in bladder umbrella cells requires phosphorylation of ADAM17 Ser-811 and EGF receptor transactivation. Mol Biol Cell 25:3798-812
|Schuler, P J; Saze, Z; Hong, C-S et al. (2014) Human CD4+ CD39+ regulatory T cells produce adenosine upon co-expression of surface CD73 or contact with CD73+ exosomes or CD73+ cells. Clin Exp Immunol 177:531-43
|Chen, Jingxin; Kleyman, Thomas R; Sheng, Shaohu (2014) Deletion of ?-subunit exon 11 of the epithelial Na+ channel reveals a regulatory module. Am J Physiol Renal Physiol 306:F561-7
|Hecht, Karen A; O'Donnell, Allyson F; Brodsky, Jeffrey L (2014) The proteolytic landscape of the yeast vacuole. Cell Logist 4:e28023
|Nirmal, J; Wolf-Johnston, A S; Chancellor, M B et al. (2014) Liposomal inhibition of acrolein-induced injury in rat cultured urothelial cells. Int Urol Nephrol 46:1947-52
|Yao, Mingyi; Rogers, Natasha M; Csányi, Gábor et al. (2014) Thrombospondin-1 activation of signal-regulatory protein-? stimulates reactive oxygen species production and promotes renal ischemia reperfusion injury. J Am Soc Nephrol 25:1171-86
Showing the most recent 10 out of 156 publications


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Exactly What Homeowners Should Consider Whenever RedesigningThe lavatory is among the most forgotten places associated with a residence. In relation to remodeling, many individuals either consider the cooking area or the bedroom. Nonetheless, you'll find lots of bathroom remodel ideas in which will be really worth the trouble.
If perhaps you might be a homeowner who's going to be thinking of remodeling your bathroom, you need to look at the particular spot you have available. Your bathroom is among the far more smaller sized places within a residence. Exactly what does this imply? This means that, until you intend on pulling down a handful of walls and expanding, you likely won't have a large amount of room to actually use. That said, a homeowner may choose to take into account the particular area they have got available when looking to renovate.
It does not take a whole lot to be able to uplift and replenish the particular appearance of a stale bathroom. Many house owners imagine that thousands of dollars must be used in an effort to make a boring bathroom appear incredible once more. All you need are a handful of simple alterations. For instance, contemporary bathroom vanities are usually a fantastic place to begin. By just swapping the particular vanity mirror of your bathroom you are able to enhance the room's entire style and allure.
This just proves that you have loads of challenges you'll have to confront in relation to remodeling a bathroom. Once again, the majority of restrooms happen to be fairly modest which suggests one is going to need to let the creativity flow if they want to make the best of their very own redesigning efforts. Additionally, keep in mind that plenty of small improvements to some sort of lavatory could make a tremendous difference in the end.


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I just wanted to know if it was a good idea to keep on higher level maths until leaving cert or if I should just go down to ordinary level.
Have a look at the course to see if you think you will eventually be able to do it and at the moment if your failing or just scraping a pass take that into consideration. If you are in need for a lot of points for a course take honours maths because you get bonus points anyway


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|Publication number
|Publication type
|Application number
|Publication date
|Oct 14, 2008
|Filing date
|Nov 6, 2003
|Priority date
|Nov 6, 2003
|Fee status
|Also published as
|Publication number
|Eric B. Stenzel
|Original Assignee
|Boston Scientific Scimed, Inc.
|Export Citation
|BiBTeX, EndNote, RefMan
|Patent Citations (26), Referenced by (35), Classifications (14), Legal Events (6)
|External Links: USPTO, USPTO Assignment, Espacenet
The present invention relates to the controlled delivery of therapeutic agents to a target site of an organic vessel.
Medical implants are used for a number of medical purposes, including the reinforcement of recently re-enlarged lumens, the replacement of ruptured vessels, and the treatment of disease such as vascular disease by local pharmacotherapy, i.e., delivering therapeutic drug doses to target tissues while minimizing systemic side effects. Such localized delivery of therapeutic agents has been proposed or achieved using medical implants which both support a lumen within a patient's body and place appropriate coatings containing absorbable therapeutic agents at the implant location.
The delivery of expandable stents is a specific example of a medical procedure that involves the deployment of coated implants. Expandable stents are tube-like medical devices, typically made from stainless steel, Tantalum, Platinum or Nitinol alloys, designed to be placed within the inner walls of a lumen within the body of a patient. These stents are typically maneuvered to a desired location within a lumen of the patient's body and then expanded to provide internal support for the lumen. The stents may be self-expanding or, alternatively, may require external forces to expand them, such as by inflating a balloon attached to the distal end of the stent delivery catheter.
Because of the direct contact of the stent with the inner walls of the lumen, stents have been coated with various compounds and therapeutic agents to enhance their effectiveness. These coatings may, among other things, be designed to facilitate the acceptance of the stent into its applied surroundings. Such coatings may also be designed to facilitate the delivery of one or more therapeutic agents to the target site for treating, preventing, or otherwise affecting the course of a disease or tissue or organ dysfunction. The coatings are typically on the order of 3 μm to 100 μm in thickness.
Where a stent is to be coated, care must be taken during its manufacture to ensure the coating is properly applied and firmly adherent to the stent. When the amount of coating is insufficient or is depleted through stripping of poorly adherent coating during manufacture or deployment within the patient's body, the implant's effectiveness may be compromised, and additional risks may be introduced. For example, when the coating of the implant includes a therapeutic, if some of the coating were removed during deployment, the therapeutic may no longer be able to be administered to the target site the desired manner. Similarly, if the therapeutic is ripped from the implant, it can reduce or slow down the blood flowing past it, thereby increasing the threat of thrombosis or, if it becomes dislodged, the risk of embolisms. In certain circumstances, the removal and reinsertion of the stent through a second medical procedure may be required where the coatings have been damaged or are defective.
The mechanical process of applying a coating onto a stent may be accomplished in a variety of ways, including, for example, spraying the coating substance onto the stent, so-called spin-dipping, i.e., dipping a spinning stent into a coating solution to achieve the desired coating, and electrohydrodynamic fluid deposition, i.e., applying an electrical potential difference between a coating fluid and a target to cause the coating fluid to be discharged from the dispensing point and drawn toward the target.
Common to these processes is the need to apply the coating such that the delivery rate can be predictably controlled. For example, in certain applications the goal may be the uniform delivery of the active substance while in other applications the desired effect would be a slow, sustained release of the active substance. Conventional methods include applying the active substance(s) in combination with a polymer to the surface of an implantable device. The drug is released as it elutes through the polymer material when it is placed in the body. One disadvantage of this method is that the polymer material and its composition control the drug's release rate. Another disadvantage is that the polymer provides only one release rate.
For example, the delivery of DNA or therapeutic agent can be inefficient, requiring large amounts of DNA and long delivery times for the stent to be an effective delivery system. This in turn can require large amounts of polymer coating on the stent, adapted to hold and release the DNA over the required period of time. However, if the coating is too thick, expansion of the stent can cause cracking of the coating, thus reducing the effectiveness of the coating. In addition, excessive coating may also cover the open areas in the stent, which normally allow passage of oxygen into the walls of the artery. On the other hand, if the coating is too thin, the entire supply of DNA or the therapeutic agent can be released within a short frame of time.
Controlled drug delivery from medical device coatings is desirable. As described, the conventional technologies rely on bulk release of therapeutic agents from carrier coatings. In this manner, often a rapid burst of the therapeutic agent occurs.
In one embodiment, the medical device for insertion or implantation in a body includes a structure and at least one therapeutic composition deposited on the structure. The structure can include a first and a second site with therapeutic composition(s) deposited on each site. The therapeutic composition at the first site can be covered with a first protective layer and the therapeutic composition at the second site can be covered with a second protective layer such that the first protective layer provides a faster in vivo decomposition rate relative to the second protective layer, thus enabling the release of the therapeutic composition from the first site at a faster rate than the release rate of the therapeutic composition from the second site.
In another embodiment, each site can have the form of a micro coated pellet (or coated pellets) with each coated pellet including at least one active substance. The active substance can include one or more of the therapeutic agents alone or in combination with excipients and/or placebo. The coated pellets can also include a combination of an active substance with a polymeric composition that covers at least a portion of the active substance. In one embodiment of the invention, each coated pellet can include a micro coating layer substantially covering a core which contains the active substance. In another embodiment, the active substance can be entirely encapsulated by the coating layer. The coated pellets can be similar or dissimilar in composition, size, release rate or decomposition rate.
In yet another embodiment, the invention comprises a stent having deposited thereon a plurality of pellets having one or more coating layers that act as a protective layer. A plurality of coated pellets having a similar release profiles or decomposition rates can be arranged together to form a region. The regions can be discontiguous and/or disconnected. Regions having different release profiles can be positioned linearly along the longitudinal axis of the stent, or as rings around the periphery of the stent, or in any suitable arrangement.
In still another embodiment, the invention comprises a process for preparing a medical device with time-release properties including providing a bio-compatible structure; depositing a therapeutic composition and a protective layer on the structure at a first location and depositing a second therapeutic composition and a protective layer on the structure at a second location. The therapeutic composition and protective layer at the first and the second locations are selected such that the therapeutic composition from the first location is released faster than the therapeutic composition from the second location.
These and other embodiments of the invention will be better understood with reference to the following exemplary drawings, where:
While the underlying structure 110 represented in
Further in reference to
In one embodiment, adhesive layer 120 comprises a photo-cure polymer that can be activated through exposure to light of a particular wavelength. In another embodiment, adhesive layer 120 comprises a thermally-activated polymer. According to this embodiment, once the micro coated pellets are placed on adhesive layer 120, they can be bonded to the stent strut 110 by heating the substrate and/or the adhesive layer to cure adhesive layer 120. Adhesive layer 120 can be applied by any conventional or known method including, for example, coating, spraying, brushing, contact transfer and electrodynamic coating.
Referring to
The micro coated pellets can be arranged according to their expected release profile or decomposition rate. For example, assuming that micro pellets 130, 140, 150 and 160 have different release profiles, they can be arranged on the structure 110 such that micro coated pellets having a substantially similar release profile are not immediately adjacent to each other. In this embodiment, the surface of the structure can be coated to have micro pellets 130 placed along the longitudinal axis of the stent and in a columnar arrangement. With this arrangement, repeating columns of micro coated pellets 130 are adjacent to, for example, columns of micro coated pellets 140 and 160. A similar arrangement can be implemented circumferentially around the periphery of the stent. In this embodiment, repeating rows of micro coated pellets 130 appear as rings around the circumference of the stent. An advantage of this and other similar arrangements is that the coated device has a predictable, and similar release profile throughout its surface. In other words, such an arrangement can predictably release an active substance simultaneously throughout the body of the stent.
Alternatively, the application may demand arranging the micro coated pellets such that the composition(s) at one region, or one end, of the stent would dissolve faster than the composition(s) at other regions. According to this embodiment, it can be predictably said that, for example, the distal end of the stent will begin releasing the active substance long after the proximal end of the stent is depleted.
Because the release profile of a micro coated pellet can be quantified according to the type and the amount of the polymer or biodegradable layer covering the active substance, designers can pre-define a release profile of the medical device by defining the polymer or biodegradable layer and its dissolution characteristics. The amount of the active substance can also be varied according to the desired effect.
In another embodiment, the material covering the active substance can be a porous material that will allow the active substance to leach or elute through the porous openings.
For example, core 210 can be micro coated with a protective biodegradable material that dissolves at a rate of 50% per hour while another core can be micro coated with a protective biodegradable material that dissolves at a rate of 5% per hour. If these two pellets were placed adjacent to each other on a strut, the first pellet having the faster solubility rate will begin to release the drug mixture first. After some time, the polymer coating of the second pellet will dissolve away, and the drug mixture of the second pellet begins to enter the body. Thus, multiple micro coated pellets with different dissolution rates can be placed along a segment of a structure to provide a device with pre-defined time-release characteristics.
In another embodiment, core 210 can include a polymer material mixed with an active ingredient that can elute the active ingredient over a period of time after the micro-coating 210 has partially or completely dissolved. In the exemplary embodiment of
As can be seen from
Referring to
Referring to
While the exemplary embodiments of
In the exemplary embodiment of
In this regard, it should be noted that the therapeutic/polymer/placebo mix can be adjusted to control the dosage of elution rate as well as the varying of the micro-coating layer thickness can be adjusted to define the time period before therapeutic elution begins.
The exemplary micro-coated pellet of
The exemplary micro-coated pellet of
In the exemplary embodiment of
The micro coated pellets can be of the same size or can have different sizes depending on the desired release rate and/or the underlying drug composition. To keep the micro coated pellets at substantially the same size, the pellets with the fastest release rate can contain some inert chemical, such as mannitol. If the pellets having the faster release rate are supplied with a thinner micro coating, the addition of an inert compound would serve to increase the volume of the pellet while keeping the drug content constant. In one embodiment of the invention, the pellet size is less than 50 μm.
In a method according to one embodiment of the present invention, a mandrel is placed through an uncoated stent to provide structural support. Then the top surface of the stent (the surface not in contact with the mandrel) is coated with a bio-compatible adhesive layer. The coating process can be done by any number of techniques, including rolling, spraying and roll-to-roll transfer. Once a sufficient amount of adhesive is coated on the stent, micro coated pellets can be imbedded on the stent until all or a portion of the stent is covered. The micro coated pellets can also be supplied to the extent necessary to deliver only the desired amount of the active substance. In one exemplary embodiment of the invention, the micro coated pellets are embedded on the surface of the stent circumferentially as rings with each adjacent ring, line or pellet having a different release rate. Once the micro coated pellets are positioned, the adhesive can be cured to maintain the pellets in place. After curing, the stent can be air brushed to remove the loose pellets. While in this embodiment of the invention, the micro coated pellets are secured to the stent with an adhesive, the principles of the invention are not limited thereto and it is understood that any method for securing the micro pellets to the surface of the stent is deemed to be well within the scope of the invention. For example, the pellets can be sprayed or coated with an adhesive and attached to the device. Alternatively, the pellets can be coated with a material such as a biodegradable wax and placed on the device. Once the pellets and/or the device is heated, the wax melts and adheres the pellets to the surface of the device.
In another embodiment of the invention the micro coated pellets are imbedded on the stent structure by scribing lines (such as aperture, via, bore, groove, cavity, gap or notch) in a blank plate to a set depth and width, filling the scribed lines with micro coated pellets in the desired order, introducing an adhesive or other tacky substance over the stent structure, rolling the stent over the pellet-loaded scribed tray so that the pellets adhere to the stent, substrate and curing the adhesive.
In still another embodiment of the invention, the pellets are arranged on a tacky sheet, the structure is coated with an adhesive tackier than the sheet, and the pellets are transferred to the structure from the sheet after the sheet is imposed and impressed on the structure. Once the tacky sheet is removed and the adhesive on the structure is cured, the pellets will remain embedded on the structure. In an alternative embodiment, the structure is cured with the tacky sheet in place and the sheet is removed after the adhesive on the structure is cured.
In a further embodiment, that adhesive layer can be a polymer material that is mixed with the therapeutic agent that is on the device to form a matrix layer. The matrix layer will elute therapeutic agent over a period of time.
In yet another embodiment, using electrostatic attraction of charged particles (or micro pellets) to a grounded plate, the micro coated pellets are deposited on the end of a flat-tipped blade. The blade is then rolled around the periphery of the stent to make contact around the stent (forming rings) or contacted along the length of the stent from end to end (forming lines). The stent can be optionally coated with an adhesive to receive the micro coated pellets. By cleaning the blade and repeating this procedure for pellets of different composition and/or size, a desired arrangement of micro coated pellets can be obtained.
In another embodiment of the invention, using a precision industrial pick and place system along with a vision system, individual pellets can be placed and imbedded on the desired location of the stent strut. If the stent is pre-coated with adhesive, curing the adhesive would bond the micro coated pellets to its surface.
In still another embodiment, using thin strands of adhesive paper or other tacky strips, thin strips of adhesive can be coated with a range of pellets prior to placing the coated strip in a fixture. Once the fixture is occupied with sufficient number of strands, the stent can be rolled over the strands to effectively transfer the micro coated pellets to the surface of the stent. Alternatively, the strands can be wrapper around the stent. If the stent is provided with an adhesive coating, the coating can be cured to further secure the micro coated pellets thereto.
The term "active substance" and "therapeutic agent" as used herein includes one or more "therapeutic agents" or "drugs". The terms "active substance", "therapeutic agents" and "drugs" are used interchangeably herein and include pharmaceutically active compounds, nucleic acids with and without carrier vectors such as lipids, compacting agents (such as histones), virus (such as adenovirus, andenoassociated virus, retrovirus, lentivirus and α-virus), polymers, hyaluronic acid, proteins, cells and the like, with or without targeting sequences. Specific examples of therapeutic agents used in conjunction with the present invention include, for example, pharmaceutically active compounds, proteins, cells, oligonucleotides, ribozymes, anti-sense oligonucleotides, DNA compacting agents, gene/vector systems (i.e., any vehicle that allows for the uptake and expression of nucleic acids), nucleic acids (including, for example, recombinant nucleic acids; naked DNA, cDNA, RNA; genomic DNA, cDNA or RNA in a non-infectious vector or in a viral vector and which further may have attached peptide targeting sequences; antisense nucleic acid (RNA or DNA); and DNA chimeras which include gene sequences and encoding for ferry proteins such as membrane translocating sequences ("MTS") and herpes simplex virus-1 ("VP22")), and viral, liposomes and cationic and anionic polymers and neutral polymers that are selected from a number of types depending on the desired application. Non-limiting examples of virus vectors or vectors derived from viral sources include adenoviral vectors, herpes simplex vectors, papilloma vectors, adeno-associated vectors, retroviral vectors, and the like. Non-limiting examples of biologically active solutes include anti-thrombogenic agents such as heparin, heparin derivatives, urokinase, and PPACK (dextrophenylalanine proline arginine chloromethylketone); antioxidants such as probucol and retinoic acid; angiogenic and anti-angiogenic agents and factors; agents blocking smooth muscle cell proliferation such as rapamycin, angiopeptin, and monoclonal antibodies capable of blocking smooth muscle cell proliferation; anti-inflammatory agents such as dexamethasone, prednisolone, corticosterone, budesonide, estrogen, sulfasalazine, acetyl salicylic acid, and mesalamine; calcium entry blockers such as verapamil, diltiazem and nifedipine; antineoplastic/antiproliferative/anti-mitotic agents such as paclitaxel, 5-fluorouracil, methotrexate, doxorubicin, daunorubicin, cyclosporine, cisplatin, vinblastine, vincristine, epothilones, endostatin, angiostatin and thymidine kinase inhibitors; antimicrobials such as triclosan, cephalosporins, aminoglycosides, and nitorfurantoin; anesthetic agents such as lidocaine, bupivacaine, and ropivacaine; nitric oxide (NO) donors such as lisidomine, molsidomine, L-arginine, NO-protein adducts, NO-carbohydrate adducts, polymeric or oligomeric NO adducts; anti-coagulants such as D-Phe-Pro-Arg chloromethyl ketone, an RGD peptide-containing compound, heparin, antithrombin compounds, platelet receptor antagonists, anti-thrombin antibodies, anti-platelet receptor antibodies, enoxaparin, hirudin, Warafin sodium, Dicumarol, aspirin, prostaglandin inhibitors, platelet inhibitors and tick antiplatelet factors; vascular cell growth promotors such as growth factors, growth factor receptor antagonists, transcriptional activators, and translational promotors; vascular cell growth inhibitors such as growth factor inhibitors, growth factor receptor antagonists, transcriptional repressors, translational repressors, replication inhibitors, inhibitory antibodies, antibodies directed against growth factors, bifunctional molecules consisting of a growth factor and a cytotoxin, bifunctional molecules consisting of an antibody and a cytotoxin; cholesterol-lowering agents; vasodilating agents; agents which interfere with endogeneus vascoactive mechanisms; survival genes which protect against cell death, such as anti-apoptotic Bcl-2 family factors and Akt kinase; and combinations thereof. Cells can be of human origin (autologous or allogenic) or from an animal source (xenogeneic), genetically engineered if desired to deliver proteins of interest at the insertion site. Any modifications are routinely made by one skilled in the art.
Polynucleotide sequences useful in practice of the invention include DNA or RNA sequences having a therapeutic effect after being taken up by a cell. Examples of therapeutic polynucleotides include anti-sense DNA and RNA; DNA coding for an anti-sense RNA; or DNA coding for tRNA or rRNA to replace defective or deficient endogenous molecules. The polynucleotides can also code for therapeutic proteins or polypeptides. A polypeptide is understood to be any translation product of a polynucleotide regardless of size, and whether glycosylated or not. Therapeutic proteins and polypeptides include as a primary example, those proteins or polypeptides that can compensate for defective or deficient species in an animal, or those that act through toxic effects to limit or remove harmful cells from the body. In addition, the polypeptides or proteins that can be injected, or whose DNA can be incorporated, include without limitation, angiogenic factors and other molecules competent to induce angiogenesis, including acidic and basic fibroblast growth factors, vascular endothelial growth factor, hif-1, epidermal growth factor, transforming growth factor α and β, platelet-derived endothelial growth factor, platelet-derived growth factor, tumor necrosis factor α, hepatocyte growth factor and insulin like growth factor; growth factors; cell cycle inhibitors including CDK inhibitors; anti-restenosis agents, including p15, p16, p18, p19, p21, p27, p53, p57, Rb, nFkB and E2F decoys, thymidine kinase ("TK") and combinations thereof and other agents useful for interfering with cell proliferation, including agents for treating malignancies; and combinations thereof. Still other useful factors, which can be provided as polypeptides or as DNA encoding these polypeptides, include monocyte chemoattractant protein ("MCP-1"), and the family of bone morphogenic proteins ("BMP's"). The known proteins include BMP-2, BMP-3, BMP-4, BMP-5, BMP-6 (Vgr-1), BMP-7 (OP-1), BMP-8, BMP-9, BMP-10, BMP-11, BMP-12, BMP-13, BMP-14, BMP-15, and BMP-16. Currently preferred BMP's are any of BMP-2, BMP-3, BMP-4, BMP-5, BMP-6 and BMP-7. These dimeric proteins can be provided as homodimers, heterodimers, or combinations thereof, alone or together with other molecules. Alternatively or, in addition, molecules capable of inducing an upstream or downstream effect of a BMP can be provided. Such molecules include any of the "hedgehog" proteins, or the DNA's encoding them.
It will be recognized by one of ordinary skill in the art that the embodiments and examples described and illustrated herein are merely illustrative, as numerous other embodiments or permutations thereof may be implemented without departing from the spirit and scope of the present invention.
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|Anti-Infective Spinal Rod with Surface Features
|U.S. Classification
|623/1.46, 426/423
|International Classification
|Cooperative Classification
|European Classification
|Nov 6, 2003
Owner name: SCIMED LIFE SYSTEMS, INC., MINNESOTA
Free format text: ASSIGNMENT OF ASSIGNORS INTEREST;ASSIGNOR:STENZEL, ERIC B.;REEL/FRAME:014685/0427
Effective date: 20031030
|Apr 18, 2006
Owner name: BOSTON SCIENTIFIC SCIMED, INC., MINNESOTA
Free format text: CHANGE OF NAME;ASSIGNOR:SCIMED LIFE SYSTEMS, INC.;REEL/FRAME:017798/0848
Effective date: 20041222
|Nov 6, 2006
Owner name: BOSTON SCIENTIFIC SCIMED, INC., MINNESOTA
Free format text: CHANGE OF NAME;ASSIGNOR:SCIMED LIFE SYSTEMS, INC.;REEL/FRAME:018505/0868
Effective date: 20050101
Owner name: BOSTON SCIENTIFIC SCIMED, INC.,MINNESOTA
Free format text: CHANGE OF NAME;ASSIGNOR:SCIMED LIFE SYSTEMS, INC.;REEL/FRAME:018505/0868
Effective date: 20050101
|Sep 22, 2009
|Certificate of correction
|Mar 14, 2012
|Fee payment
Year of fee payment: 4
|Mar 30, 2016
|Fee payment
Year of fee payment: 8


text:
sylvia12345 Review
made of crap and breaks down immediately beyond re
it's made of composite wood chips; the screws pull out, the doors fall off. I threw it out after 6 months
- How did the color on site compare with the actual product? well
- Please tell us about the quality of the product. s***t
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Bedford crash injures two
BEDFORD - Two people were injured Wednesday night in a crash at the intersection of Route 101 and Hitching Post Lane, police said.
Police said one of the cars T-boned the other about 7:50 p.m. Wednesday. The drivers of each car - police did not provide their names - were taken to "local area hospitals for evaluation" after suffering unknown injuries, police said in a release.
Alcohol and speed do not appear to factors in the accident, police said.
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I don't know if Raising Hope has gotten better, but I certainly like it more. Garret Dillahunt is amazing. Read More »
Home / Tag Archives: Terminator: The Sarah Connor Chronicles
Echoes of Eliza: Eliza Dushku Dishes on Dollhouse
Producer and star of Joss Whedon's Dollhouse, Eliza Dushku chats with reporters about season two. Read More »


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This review is from: Logitech Wireless Gaming Headset G930 with 7.1 Surround Sound, Wireless Headphones with Microphone
Pros: The headset sits nicely on the head and are very light weight. The g-keys are also a very nice feature but the con list is very large.
Cons: The headset looses connection with the base unit a lot. I tried moving the base far away and I tried with the base right beside me made know difference. I just stopped using these since its really a annoying having to here the noise of loosing connection to the base. I also tried moving the USB stick in all my USB ports that made know difference. I would say Buyer Beware. Don't waist your money on these.
One last thing the sound is very dull its not full and it's very tinny sounding.
This review is from: APRICORN ASW-USB-25 USB 2.0 to SATA Adapter
Pros: Software included and very easy to use just insert disk and plug cable in to the drive then the pc and just follow the on screen guide.
Cons: None.READ FULL REVIEW
This review is from: SAMSUNG 840 EVO MZ-7TE120BW 2.5" 120GB SATA III TLC Internal Solid State Drive (SSD)
Pros: Got this when it was on sale!
Cons: This drive does not come with any screws. Samsung has failed to say this & newegg has also failed at it. I will stick to corsair ssd, ram, psuREAD FULL REVIEW


text: I really, really want this to be true and I really, really want to get shots of the candid reactions to Dita's dancing from Charles and Harry. Charles was eventually told by his aides what kind of dancing Teese did and he supposedly was embarrassed that he requested her as a performer, but a girl can still dream that this might not only be true but come true. Only time will tell.


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1. Preheat the oven at 400 degrees F.
2. Using a short glass, cut 24 rounds from the puff pastry sheet. Set aside in a baking tray.
3. Bake the puff pastries for 8- 10 minutes at 400 degrees F.
4. Take out the puffs from the oven and let it cool on cooling rack. Once cooled, slice the puffs in between using a serrated knife and set aside.
5. In a mixing bowl, add in the cream cheese, crab meat, green onion, milk, almond, horseradish, black pepper and paprika. Mix all the ingredients well.
6. Spoon the mixture on the lower slice of puffs and close with other half
7. Decorate the plate with basil, arrange puffs in between, sprinkle paprika and serve.
For more recipes please visit The Brown Lounge Website
Serving size Per servingComplete recipe
Calories 264 Calories from Fat 176
% Daily Value*
Total Fat 20 g30.4%
Saturated Fat 6.7 g33.3%
Trans Fat 0 g
Cholesterol 28.3 mg9.4%
Sodium 293.4 mg12.2%
Total Carbohydrates 16 g5.2%
Dietary Fiber 1.9 g7.7%
Sugars 2 g
Protein 6 g13%
Vitamin A 9.4%
Vitamin C 3.1%
Calcium 3.9%
Iron 2.6%
*Based on a 2000 Calorie diet


text: Deal 22 clicks 50% off First Washington Post Wine Club Shipment Receive 50% off First Washington Post Wine Club Shipment. Your two cents Share GET PROMO CODE Did this coupon work for you? YES NO Share this exclusive offer with others! Copy this link and share it anywhere Copy Tweet Share Add comment Leave the community your two cents … Your name


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live video streaming issues
I have a few apps like live stream, which airs Live TV from the UK such as sky news, France 24 etc etc, it comes in pixilated with staticy lines. But this doesn't happen in live streams from other apps like my cablevision app or Netflix or other streaming apps. Any ideas? Btw the troubled ones work fine on my note 10.1 2014 edition.
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The Abrams Chair Conference: Jewish Religious Expression in Byzantine Palestine
Wednesday, Oct. 31, 2012, Notre Dame Conference Center, McKenna Hall
Conference Schedule
Accommodations and Directions
The University of Notre Dame Theology Department and the Abrams family present this conference in honor of Professor Tzvi Novick's appointment as Abrams College Chair of Jewish Thought and Culture.
Online Registration is now closed. Please contact Emily Hammock with questions!
Featured Speakers:
Marc Bregman
University of North Carolina at Greensboro
From Sermon to Scroll to Codex: The Early History of the Hebrew Book
Steven Fraade
Yale University
Language Switching in the Byzantine Synagogue Inscriptions and the Practice of Targum
Martha Himmelfarb
Princeton University
The Suffering Servant in the Seventh Century: The Messiah in a Liturgical Poem for the Day of Atonement
Michael Swartz
Ohio State University
As Above, So Below: Cosmology and Cult in Ancient Synagogue Poetry
Tzvi Novick
University of Notre Dame
Concluding Remarks


text:
Max Weber
Readings and Commentary on Modernity
Edited by Stephen Kalberg
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Max Weber by Stephen Kalberg
Book DescriptionThis unique volume gathers Webera s writings on a broad array of themes, from the nature of work, to the political culture of democracy, to the uniqueness of the West, to the character of the family and race relations, to the role of science and the fate of ethical action in the modern world. * Gathers Weber's writings in a comprehensive collection, organized by topic. * Rejuvenates a central, pivotal theme of Weberian thought: "How do we live?" and "How can we live in the industrial society?" * Connects Weber's writings to contemporary issues through modern essays and editorial introductions.
Buy Max Weber book by Stephen Kalberg from Australia's Online Bookstore, Boomerang Books.
Book DetailsISBN: 9780631214892
(237mm x 164mm x 31mm)
Pages: 432
Imprint: Blackwell Publishers
Publisher: John Wiley and Sons Ltd
Publish Date: 16-Dec-2004
Country of Publication: United Kingdom
Other Editions...
Books By Author Stephen Kalberg
Searching for the Spirit of American Democracy, Paperback (December 2014)
Rich new insights into the particular contours of today's American political culture, based on Max Weber's insights.
Protestant Ethic and the Spirit of Capitalism with Other Writings on the Rise of the West, Paperback (December 2008)
With new enhanced pedagogy, this is a famous translation of a classic book - now available for the first time with "Other Writings on the Rise of the West", a collection of Weber's other diverse writings.
Max Weber, Paperback (December 2004)» View all books by Stephen Kalberg
A collection of Weber's writings on a broad array of themes, from the nature of work, to the political culture of democracy, to the uniqueness of the West, to the character of the family and race relations, to the role of science and the fate of ethical action in the modern world.
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Author Biography - Stephen Kalberg
Stephen Kalberg is Associate Professor of Sociology at Boston University and one of the worlda s leading Weber scholars. He is the author of Max Webera s Comparative Historical Sociology (1993) and translator and editor of a new edition of Webera s Protestant Ethic and the Spirit of Capitalism (Blackwell, 2001).
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Contacts updated in Outlook are not updated on device BES Sync
I have 1 user with a Bold 9650 that keeps having problems with his contacts. I've updated the device with the Verizon OTA updates and that resolved the issues for a time, but now the device isn't showing changes to contacts that are made in Outlook. Any ideas?
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What errors are showing if any in the BES logs?
Does the calender still sync fine after the updates?
Do updates on the device show in Outlook?
What TS have you done so far?
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The Gray Ghost features a gray latex top reed over two clear bottom reeds and produces the sweet throaty yelps of a wild turkey hen. This call breaks from high to mellow rasp and is ideal for producing the softer kee kee's, clucks, and yelps of a content hen. Perfect for finishing off that longbeard that has hung up just out of gun range, this call should be in every serious turkey hunter's vest.'
Woodhaven Stinger Pro Series GrayGhost Cutter Diaphragm Turkey Call
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The statements and opinions expressed within Customer Reviews reflect each author's personal perspective and do not imply endorsement by MidwayUSA, its Employees or any other organization. Customers should in no way infer that MidwayUSA has validated review information as safe, accurate or appropriate.


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Why Hire a Wedding Planner?
Hiring a wedding planner is no longer an extravagant luxury for large, elaborate weddings. Instead, it's simply a sensible option if you'd prefer to
Konfidence Events Services provides a personal, friendly and reliable service to all our clients. Whatever the event, we know how important it is to you and ensure that every detail is accounted for. We plan and produce memorable and high quality Events, Private Parties and Weddings including table decor, props, entertainment catering and venue selection. We attend industry conferences across the UK and globally to keep on trend and to ensure every client's event is creative, exciting and unique!
I'm lost for words, the layout was absolutely fantastic! We walked into our venue and it took our breath away! Everyone was talking about how beautiful the decor looked. Thank you Tammy for turning our dreams into reality
Hi Tammy,Thank you so much for the decorations they were absolutely beautiful. Everyone commented on how stunning the room looked. You really did a fantastic job and helped make our day special. Thanks again – will certainly be recommending you to others.
My daughter's had her party in December last year & I loved the way they managed the children and kept them entertained for the whole time. It made us free from all the worries and we as parents also joined the fun. Thanks very much Tammy and I will definitely come back to u soon.
A big thanks to Tammy for organising a fab birthday party for my son's 3rd Birthday. My son and all his friends had a total blast. The party entertainer was really good and all the parents were also having a good time and were so involved. I totally recommend Konfidence Events!
Konfidence Events plan elegant, stylish, glamorous and fun celebrations and cater for couples who demand first class service and a world-class event.
Timeless and beautiful weddings are the result of careful collaboration, efficient organisation and meticulous attention to detail. Our flexible wedding planning services will bring a calm and reassuring quality to every element of your day to ensure absolute perfection.
Whether you'd like our help organising your entire wedding, managing the day itself, creating the design for your day or finding the perfect venue for you, we'll be only too happy to tailor our services to suit your needs.
We also offer an initial free, no-obligation consultation so that we can find out more about you, your ideas and the level of support you require. So if you're not sure where to start or if there's something specific you'd like to discuss, then please do get in touch.
The planning of a party or event can be a huge job, time consuming and stressful – that's why we have a specialised team of experienced party planners on board to dedicate themselves to your event.
If you're looking for an unforgettable experience for your special occasion, you've come to the right place. Konfidence Events offers full service party planning to take care of the party venue, party invitations, thematic decoration set-up, entertainment, food catering, birthday cakes or any other celebration accessories. Our motto is to plan & deliver a stress free magical experience for your event no matter the occasion.
Through our nationwide network of artists, DJ's and support staff we can provide what you need to make your party a success, be that, private parties, Christmas parties, product and venue launches and exhibitions. We provide the same level of service regardless of how large or small the event and believe working closely with you is the way to make your event the best it can be.
Our goal is always to provide the best, most dependable service you need during the planning of your party and we know only too well that when it comes to the entertainment you want it to be something your guests will remember for all the right reasons. With a wealth of talent and experience we believe we can give you a party to remember.
If you're looking to plan the perfect christening party or naming ceremony then you've come to the right place!
Your baby's christening party is a really special moment to be treasured, so Konfidence Events will make sure every little detail is just right from the right colour balloons and decorations to linen, catering, drinks and music or live entertainment.
Your venue can be themed in any way you wish from formal or casual to simple or elaborate, intimate or big and bold. Whatever you want for your baby's special day, Konfidence Events will completely tailor your party to your requirements.
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Konfidence Events provides professional Baby Shower Planning services, so if you find that you are overwhelmed with all the details and looking for assistance with set-up and management of the big day, we are here to help and ensure that your event is in good hands so you can enjoy your event as host, just as much as the mommy-to-be!
We have found that there is simply no substitute for an event planner that can be on-site and ready to respond to any challenge or unexpected issue. With keen professional eyes on the scene, able to act wisely, yet decisively, Konfidence Events are also able to offer an on-site management service that enables your once in a lifetime event to reach its maximum potential in success, creating a special memory for each of your guests.
We want you to be "stress free" for one of the most memorable events in your life. We have various packages available that includes chairs, tables, centre pieces, table covers, and many more options.
Our goal is to provide you with a beautiful set up to celebrate your special event and whilst delighting & entertaining everyone who is there so that your Baby Shower is as individual and special as you are.
Anniversary parties are special events and not only do they bring back all the memories of the special day, but they are also a celebration of the continuing commitment with the chance for friends and relations to join in and show their love and support.
We understand how a busy lifestyle may leave little time for party planning. Our complete and unique service removes unwanted stress as we listen to your vision, turn it into reality and take responsibility for it all coming together on time and within your budget.
We are passionate about creating remarkable events that meet every requirement, surpass expectations and create memories that will live with you long after the celebrations are over so whatever your thinking we can help with venue selection, ideas and experience we can offer you the best service available for your anniversary needs.
Deciding where to host a wake is a big decision. You not only need a suitable space and catering, but the reassurance of an events team that are not only professional, but also sympathetic and supportive.
Konfidence Events have significant experience in running private events of this nature and we will work with you to ensure that all of your requirements are handled both efficiently and with sensitivity.
Although a wake is a celebration of a loved-one's life, we realise that it needs to be managed discretely and respectfully allowing the family of the deceased to pay their respects in whatever way they feel to be most appropriate.
We also understand that hosting a wake is a big responsibility, and one that we take very seriously. For this reason we have made the booking process extremely simple and you will be assigned an Event Planner and Event Manager who will look after every detail. We will listen to your requests and ensure that everything is just right from the right table settings to the perfect flowers, catering, drinks, music and anything else that you may need.
Konfidence Events understand what it takes when it comes to planning corporate occasions. We have successfully planned events for clients all over the UK from gala dinners to corporate award ceremonies. We can help plan your event form start to finish providing our 5 star event management services, which involve everything from entertainment to full room styling and event decor.
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Konfidence Events can help you to plan the perfect party for your child's birthday or special occasion creating long lasting memories that both children and parents can cherish for a lifetime.
Our wedding packages are tailored to your individual needs, however a basic package is available for theses who want to keep it simple and sweet or as a starting point for inspiration.
Confetti Package :
Pearl Package :
We are able to provide an extensive selection of accessories and entertainment equipment to give your celebration that wow factor and exceed guest expectations.
Hiring a wedding planner is no longer an extravagant luxury for large, elaborate weddings. Instead, it's simply a sensible option if you'd prefer to
To a certain extent, the date will be determined by whether you want a religious or secular ceremony.
A good event can build brand awareness and improve your relationships with the people you do business with


text:
Where a Superior Court judge entered summary judgment for the defendants on the plaintiff's claim that her husband suffered from malignant mesothelioma as a result of his exposure to asbestos during his service aboard the U.S.S. Guadalcanal, that judgment was proper given that there is no evidence that the mesothelioma was caused by asbestos products manufactured by the defendants.
Tagged with: AsbestosRead More »


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I don't know if it is Folk Music or not... but it sure is attractive.
PS I've noticed Iris have a funny habit of growing feet and moving
around when you're not looking :)
--- In iris-photos@y..., Sandra Barss <barsssa@m...> wrote:
> I think this might be Folk Music. It is an intermediate.
> Folk Music ( Willot '94) is described as Lt apricot-pink w/vlt
> vlt bd.
> I did have Folk Music, but I didn't think it was where this iris was
> blooming.
> Sandra
> SE Manitoba Z3
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text:
Testing for Efficiency in Lotto Markets
State-sponsored lotto games, because they are pari-mutuel and because jackpots with no winners are rolled over into the next drawing, present an excellent opportunity to test for market efficiency. Using data from Massachusetts, Kentucky, and Ohio, the authors investigate bettors' responses and test for weak-form efficiency. Lotto bets do not have positive net expected returns, thus weak-form efficiency exists. To evaluate strong-form efficiency, the authors utilize the concept of a rational expectations equilibrium. They find that, in general, lotto bettors' decisions to play generate a level of sales that conform to their original forecasts of expected value. Copyright 1995 by Oxford University Press.
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Volume (Year): 33 (1995)
Issue (Month): 2 (April)
Pages: 175-188
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Each year, the Camdenton R-III School District Education Foundation inducts into its Hall of Leaders deserving individuals who have excelled in their field of expertise and made significant contributions to their communities.
The Foundation is asking the community's assistance to identify individuals with outstanding achievement in the areas of service and dedication to education, youth and community.
"It is our intent through this program that the Lake Area community and especially our young people see education as the foundation for success," said John Porth, president of Camdenton Education Foundation. "We hope current and future students view our Hall of Leaders inductees as role models. We believe the program also brings our community together in sharing and recognizing the successes of these exceptional individuals."
The Foundation is accepting nominations in the following categories:
Distinguished Alumni - persons who attended the Camdenton School District and have become successful in their chosen field.
Outstanding Education Professionals - teachers and administrators who have served the Camdenton School District for at least five years, have been retired for at least five years and were outstanding educational leaders in the District.
Friends of the District - persons whose efforts have made a significant contribution to the Camdenton School District; must demonstrate leadership, character and uncommon dedication to the District; this category is not limited to alumni.
This year's honorees will be celebrated at the 11th annual Elegant Evening on Friday, April 19, 2013 held at Camdenton High School (CHS). Each inductee photo is mounted with their name and biography engraved on a special Hall of Leaders plaque prominently displayed at CHS for students, staff and visitors to view.
"The Hall of Leaders display has become a place where these special individuals can be celebrated now and long into the future," explains Porth. "It gives our kids a face to connect with so they understand that not only is it important to be strong in their professional field, but it's also important to give back to the community in which they live."
Nominees do not have to reside in the Camdenton School District and may be honored posthumously. A maximum of three awards are given out in one year. No more than two awards will be given out in any category per year.
For more information, call 573-346-9213, or visit www.camdentonschools.org, click on District Info then Education Foundation to download a nomination form and application rules. Applications must be received in the Camdenton R-III School District administration office by Friday, Dec. 21.


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Tottenham Hotspur 4 Queens Park Rangers 0
If one player encapsulated Tottenham Hotspur's failure to meet expectations last season it was Erik Lamela, but after the midfielder inspired this rout the fans will hope their record signing remains a symbol of their fortunes. The Argentinian did not add to his dismal tally of one goal for Spurs, but did everything else, creating chances for Eric Dier and Nacer Chadli, who scored twice before Emmanuel Adebayor compounded Harry Redknapp's miserable return to White Hart Lane.
Lamela is clearly seeking to invert second-season syndrome. Having barely played because of injuries last season, the 22-year-old seemed eager to make up


text:
But we must act now! True sustainability will be achieved through endowed programs. Through the generous donations of members and supporters, we can envision a time when the programs of ASRM are self-supported by endowment income.
So today, whether you've had a long-term relationship with us, or are just starting out – we ask you to give from your heart. Your donation will make a difference in ASRM's Research, Education and Advocacy initiatives.
Thank you for helping us to ensure that ASRM continues to thrive not only now but in the future.
Join ASRM for the following fundraising events and ensure that ASRM can continue into the future.
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©2009 - 2016 ASRM, American Society for Reproductive Medicine. All Rights Reserved.


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Thank you, Chickenflicken. Sorry, Leta, that now you look more like me. Your hair, it will finally make sense 20 years from now, no sooner.
Posted in Daily Photo | Tagged Leta Armstrong
The parents of Leta Armstrong
Potty training begins very soon
Cautionary Tale
Magenta protective case for the iPhone 3G
spoonie, come to my crack house.
bucky, there's a pic of a kitty tongue at suburbanmisfit's house. That'll help you feel better.
I love Leta pictures. Keep em comin'!
I'm guessin' the guy's expression and body language probably contributed to the overall impression. You know, the dickhead thing.
Spoonie: I'll smoke your crack any day, butt spelunker.
I don't like discord. The negativity in here was a bit much.
I'll keep asking for advice on ghosts – but another time.
So, do you all think Demi is pregnant but just anxious to confirm until the 2nd trimester?
(I know, it's a lame change of topic, but it's that or ghost stuff from me right now. I'm a bit overtaxed)
DOOCE!!!! Congrats on the awardsss!!!!
Of course, of course. Of course you got'em. Of course I congratulate you. Of course I use 4 exclamation points!!!!
I cannot believe HOW big she is. She looks way more like a toddler than a baby these days.
Dooce, de-lurking to say congrats on the awards. Love your site, love your photos. Any positive attention is well-deserved!
I think Demi is pregnant.
Nothing, and I mean NOTHING, is worth pre-empting Ellen for. Sometimes that is the only fun part of my day (aside from catching up on the dirt here, that is).
Dance, Ellen, dance!
KBWAW: If the stuff going on in my house is the work of ghosts, so far I'd have to attest that they're fairly "Casper-esqe".
Things happening: Steroes coming on in the middle of the night, lights coming back on (not regular lights but pull chain), items disappearing, but the freakist is the tv changing channels by itself or the program guide surfing all the time on it's own.
Any ideas?
And, umm…did I smell a troll?
Or was that a presidential fart blowing through here?
I am unknown here, my name is Nicole.
I am a co-worker and sorta friend of Girl.A who I've known for 6 years and who introduced the site to me last November. I read every day and I do not comment. I don't have a blog.
For the record, over the past few weeks Katie has not seemed to change what she's doing. Sometimes, Katie, with all due respect you go too far. When I get worried about or upset with a friend I tell them. I am not being mean.
Just now I was lumped in with trolls. Which I am not. And I did not show any hate for Katie. I do not hate Katie or anyone.
And thank you "Hey, Unknown" but no thank you. I do not go for name calling or revenge. Please no one else post comments and reference me if you are going to be mean. I do not condone it. I do not agree.
I am just trying to be fair and logical about this. My friend just told me when she left for home that she is never coming back to dooce and that made me feel sad.
"Trolls say mean things to make themselves feel better.â€
This is exactly why saying mean things back is no good.
Because if saying mean things back makes us feel better, then there is something wrong.
Jeez, either I get on only at dead times, or everyone runs as soon as I make an appearance.
Or both.
Torrie: Me too. Did you see Ashton on David Letterman? He didn't actually say flat out that she was wasn't – it's all about the spin.
No trolls. A little crack, some ass-wipe talk, Presidential ghost farts, you know, the usual…
Ryan Harne, I just checked out your website and I think I heart you.
That is all.
Crud, and now that I'm here, the baby wakes up, and I'm gone again.
Bye til later
ATTACK, BABY! And bring me some crack. Butt crack.
While I agree that Dollys comment was uncalled for and down right rude I do agree with Unknown and Hey, unknown. People seem to get called ass troll just for disagreeing with either Heather or the commenters.
Today I think that heather perhaps over reacted with that guy. He was probably trying to be funny. I didn't post that comment because I figured I'd be called an asstroll.
I used to really enjoy reading the comments but now not as much. People seem to be power tripping over calling others ass trolls.
Spoonleg – I have a question. If you get pregnant while smokin' crack, is the baby a 'crackccident'?
And yeah, I'll smoke some rock witcha.
Thanks Torrie!
Much needed comic relief.
Almost time for me to go home here – ya'll take care!
It's a GIR!!!!
(That photo, by the way, is the one you should include in the Album of Humiliation… you know? That album which you're going to show to all her teenage suitors (or the suitors she'll have when she's finally allowed to date at 45, if Jon has anything to do with it).
I didn't see your last post before I wrote mine, though it was more to really just say I am not a troll.
Thank you and have a good night. I gotta go home to my kid and give her a big hug.
Ya know, the more I look at that picture the more I'm digging on the color combo. Little Leta fashion diva.
Bucky, I can just see that John Edwards guy, "Did someone in this room fart yesterday?" or "I'm getting eggs, does that ring a bell?"
and the train conductor says, take a break, driver 8,
driver 8, take a break,
we can reach our destination
Told you Leta was from Mars…
Very well said Unknown about Katie, I didn't think she'd ever see the light of day it was so far us Heather's ass.
Katie, you don't allow anon comments on your site, Heather does–apparently she can take it far more than you think she can, and well you can't.
I've found that the ones who are the bullies deep down are the most scared of all. The bigger they are the harder they fall, we all know about bullies. Katie you are one, at least on here, I doubt in real life you're as ballsy.
Let people say want they want about Heather on her site. You deal with your own life, if you can have one being on here all day long. This goes for everyone—kept your hating to yourself. You actually make the hate grow with your comments. You know who you should focus on, nuts who go looking up emails of people who send Heather emails and then start stalking them…those are some real nuts ya'll.
since when is it wrong for babies to act like babies? why do people expect children to act like well mannered grown ups? most grown ups don't act like well mannered grown ups. i do, of course, but then i have children and when you have children all rights to behaving insanely go to them. it's unfair, but there it is.
I am going to go make dinner. I can't take all of this negativity.
Where's Bucky and her monkey when you need them?
back for a sec (baby on lap), and speaking of soaps…does it bug anyone else when an actor leaves a soap for a period of years, then returns…as a different character?? Days has done that at least twice, and boy is it confusing to people like me who only get a chance to watch it sporadically…
Sorry about your friend, Unknown. I would hope that she will trust that I won't call out the ass trolls anymore. I guess it is only extending the hate to call them out. For the record, I don't think you are a troll – just a concerned Dooce fan. I appreciate your kind words and understanding, and I will stand up for you if anyone calls you a troll! But I won't be mean!
Once again, I hope your friend comes back to Dooce.com – it is not Heather that is saying the troll comments nor is she calling anyone ass trolls. I can promise I won't dole out the daily ass troll comment, although I can't promise trolls won't lurk around here. I hope your friend gives it a second chance, because everyone knows that this is a great website with a lot of fun people!!!
I love all you Dooceketeers! Can we PLEASE talk about poop now? NO MORE ASS TROLL TALK JUST POOPY TALK!!! I PROMISE I WILL STICK TO THE STICKY TOPIC OF POO!
LMAO Bethy-Mae.
I swear you people will get me laughin' so hard I puke again.
I'll bet there are way more lurkers than commenters because they don't want to get slammed for a differing opinion. There have to be to have 40,000 hits & only hundreds of comments, often many from the same dozen or so people. Hey, Katie, give the troll thing a rest please. You're allowed an opinion & so is everyone else. Thanks. See how polite that was? It IS National Courtesy Day, you know.
Bethy-mae – well you know, brown with yellow and blue stripes is the new black.
Happy to oblige, Amanda B.
Love that pick Dooce. Also, CONGRAT'S on the BLOGGIE AWARDS. That is freakin awesome!
Actually I do allow anonymous posts on my site. Visit it and you will find out. There are plenty of anonymous posts.
And I am ballsy in real life. I stick up for my beliefs and my friends. End of story.
And please refrain from calling us nuts. I don't think that was called for.
Blue stripes? Plum, I can see you've already been smoking the crack. Those stripes are white, girl!
(Aren't they?)
There's no need to avoid the Dooce site just because of comments. Just don't read them – heck, it took me a couple of days to even realize they were here! (But golly I'm glad I did!)
I though they were light blue to match the hat…But my crack-addled mind could be fooling with me. I suppose that'd explain why everyone looks like seamonsters right now, too.
I have to agree with the seamonster comment…there ain't no blue in that picture…not even light blue.
Kalki, please save me! Can you talk about poop with me please? I have started down the path of not calling people ass trolls and they keep yelling at me. Let's talk about poop!
You mean the hat with the white letters?
I, like Bucky, have a bit of the flu. I'd trust crack-induced colors over flu-induced ones anyday. Blue it is!!
Thanks Torrie!
Wait. Heck, I got Kendra backing me up now. White it is!
Kendra, since you live at the lakehead, see any lakemonsters wearing big brown hats? Squint, and believe!
C'mon, light blue anyone?
See you later alligator.
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text:
Category:National Portrait Gallery, Canberra
From Wikimedia Commons, the free media repository
English: National Portrait Gallery in Canberra, Australia.
This category has the following 2 subcategories, out of 2 total.
- ► Self-portrait (Rubens, 1623) (6 F)
Media in category "National Portrait Gallery, Canberra"
The following 5 files are in this category, out of 5 total.
- Hilda Spong12a.jpg 381 KB
- Ethel Turner-H Cazneaux.jpg 720 KB


text: I am dedicated, passionate and hard working person that is looking for any freelance job, hoping gain the experience that I need to be in a professional studio. But I also have other skills in Adobe Photoshop, Adobe Flash, and also in Adobe After Effects. I have great understanding about how a production pipeline works and have ability to meet deadlines. I always communicate with my team on my updates that I do on a project. Moreover, I also able to work alone. In conclusion, have the skills that are needed in any job


text:
"Whoo… Whoo… are turning two? Our twin owl boys, that is WHOO!" Cute boyish owls perch around your hooty birthday wording on this twin owl boys photo invitation. We can change the blue, orange, & cream colors for you (perhaps to match your party colors), and we can also include a small photo of your little owl boys, as shown here. You can see more ideas & personalize this card for your own party here (simply share your color & design preferences in the request form): Hoot Owl Twin Birthday Invitation.
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