text:
A refreshing and easy soup to enjoy in the warm weather
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- Serves:4
- Degree of difficulty:Low
- Preparation time:45 minutes
1 bunch coriander
4 stems lemon grass
4 leeks
75g butter
50ml olive oil
1 onion
4 sweet potatoes
1 litre stock
300ml cream
Remove leaves from coriander and reserve. Cut off white parts of leek and reserve. Put the roots of coriander, the greens of the leek and the chopped storks of the lemongrass in a saucepan with a litre of water. Add salt and pepper to taste. Bring to a boil then cover and simmer for 30 minutes.
Melt the butter in a large saucepan, add finely chopped leeks and onion and gently cool for about 10 minutes, stirring occasionally.
Now add the peeled and diced sweet potatoes and cook for a further 5 minutes. Pour in strained stock and simmer until potatoes are soft.
Blend until smooth, add salt and pepper to taste. Refrigerate for at least 6 hours. Just before serving mix in cream, pour into bowls and garnish with coriander leaves.
This can be made with a ready-made chicken of vegetable stock.


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Black Jack is a safe, sane, seasoned, and very smooth big guy. He has years of natural horsemanship training, and you can literally ride him bareback with…SOLD
Gorgeous Bay/White Spotted true Racking Gelding for sale. He has been there and done that attitude and is non-spooky. No vices. His most recent rider…SOLD
Hersey is one fun love'n little paint racking pony! He's dog gentle, neck reins and backs up like a quarter horse, loads, baths, easy to catch, doesn…SOLD
My bay racking horse is for sale. A 14 year old gelding. About 15 hands tall. He is well built - solid - muscular. Has a good conformation. Will rack a…SOLD
Smooth riding racking horse.SOLD
Moonshine is a very calm, quiet, well-trained Racking gelding. He has a smooth, natural 4-beat gait with no trot or pace.He is easy to handle, has no vices…SOLD
Bo is a 12 year old gaited gelding, who is 14.3 hands high. Bo has a wonderfully smooth rack, and a nice slow dog walk, and canter. He is an awesome trail…SOLD
Harley is about as good as it gets in a gaited pleasure horse. He has an awesome, smooth, 4-beat gait, and can rack at 15MPH if asked. He also has a nice…SOLD

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surround sound on regular tv download mZAu free file
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architectural design - sports clubrooms
This project received 59 bids from talented freelancers with an average bid price of $372 AUD.Get free quotes for a project like this
Project Budget$100 - $500 AUD
Total Bids59
Project Description
I am looking for an architect to design clubrooms for a sporting club, I really want a very creative design while maintaining a very tight budget on this project, so use of materials, layout, fittings etc will be key..
Design must be Environmentally Sustainable Design
I am also wanting to explore the idea of constructing as modular design if this may save some budget.
I will be needing 2 -3 exterior renders and 2 - 3 internal renders of the project.
I will provide floorplan to best possible applicants
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Liberalization under the auspices of the palace: migration reform in Morocco
The majority of irregular migrants in Morocco are from sub-Saharan Africa.
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Morocco's King Mohammed VI has been touted as a reformist leader since becoming head of state in 1999 after the death of his father, King Hassan II. The final years of Hassan's reign ushered in a government of alternance led by long-time opposition leader Abderrahman el Youssoufi (Union des Forces Populaires-USFP) in 1998. Economic liberalization and relative democratic reform became policy priorities during this time and set the stage for the transfer of power to his son.[1]
The young king delivered on some promises for change in the new millennium. These included the 2004 reform of the moudawana, or family code; establishing the Moroccan truth and reconciliation committee, the first of its kind in the Arab world; settingambitious development goals and attracting high levels of foreign direct investment; drafting a more "liberal" 2011 constitution in response to Morocco's February 20thmovement; and, most recently, overhauling the migration and asylum system.
Or so the story goes. . . .
2014 marks the fifteen-year anniversary of the reign of Mohammed VI, and the politics of co-optation have become more acute than ever. While Morocco has had a multiparty system and an increasingly vocal civil society since independence, these developments have masked the relative weakness of democratic bodies, like the parliament. The recent rise to power of the Party of Justice and Development (PJD), an Islamist group, and Prime Minister Abdelilah Benkirane has also provoked comparisons with King Hassan's successful neutralization of the leftist opposition during the 1998 alternance government.While the current king's reform efforts are not without merit, they very effectively demonstrate that political power in Morocco lies firmly within the monarchy.
The state's overhaul of the migration and asylum system is an excellent case study of how reform is centrally controlled in the kingdom. It is true that civil society was incredibly active in shedding light on the plight of irregular migrants, asylum seekers, and refugees. For the last several years, various associations have worked together to support this vulnerable group and to raise awareness about the challenges they face. These include Moroccan NGOs, such as the Anti-racist group for the Defense of Foreigners and Migrants (GADEM) in Rabat and the Beni Znassen Association for Culture, Development and Solidarity (ABCDS) in Oujda; migrant associations, such as the Council of sub-Saharan Migrants in Morocco (CMSM) and the Association Shedding Light on Clandestine Migration in the Maghreb (ALCEMA); international groups, such as Doctors without Borders-Spain, Caritas, the United Nations High Commissioner for Refugees (UNHCR), and the International Organization for Migration(IOM); as well as joint ventures, such as the immigrant division of the Moroccan syndicate, the Democratic Organization of Labor (ODT). Many of these activists have faced intimidation and arrestfor publishing reports on police abuse, racism against sub-Saharan migrants, and the limitations of a security-focused migration strategy. They have, nonetheless, voiced their concerns and criticisms to the Moroccan parliament, relevant ministries, European Union institutional bodies, and the National Human Rights Council, —a palace funded body whose representatives are chosen by the king from a list proposed by civil society groups.
2013 proved to be a pivotal year in the struggle for human rights monitoring in Morocco.Doctors without Borders published a very extensive report, which documented the dire humanitarian situation for sub-Saharan migrants in the country, as well as police abuse and judicial disregard for Morocco's domestic and international legal commitments to migrants and refugees. The BBC also aired an investigative documentary on the issue, which chipped away at Morocco's carefully crafted narrative of regional "exceptionalism."
As these abuses received increasing publicity, other developments began to encourage palace involvement in the issue. The majority of irregular migrants in Morocco are from sub-Saharan Africa, particularly from Senegal, Mali, the Ivory Coast, Guinea, Cameroon, and Nigeria.[2] For Morocco, West African countries have become viable partners for bilateral economic agreements, as well as potential avenues for reestablishing its relationship with the Africa Union; Morocco left the organization in 1984 in protest over its recognition of the Sahawari Arab Democratic Republic in the disputed Western Saharan territory. The Western Sahara has been a critical foreign policy issue for Morocco since the1975 Green March, and it continues to shape the country's political and economic relationships with sub-Saharan African countries.
King Mohammed became directly involved in the asylum and migration issue after theNational Human Rights Council published a list of recommendations to encourage antidiscrimination and more humane migration policies. In response, the king announced a total overhaul of the migration system on September 10, 2013.
The palace's platform included a process of regularization for certain categories of migrants, especially women and children. Under the plan, the Ministry of Foreign Affairs assumed responsibility for the Refugee Status Determination Process (RSD) from the United Nations High Commissioner for Refugees. These are important steps in the right direction, but they do not address the issues of racism, police violence, the "draconian" process for obtaining and renewing documentation, and the "lack of [government] consultation with associations [and civil society]."
The National Human Rights Council is presiding over the commission which adjudicates the regularization process and includes both "political authorities" and civil society groups like GADEM. As of June 2014, 16,000 requests for regularization were filed, 14,510 were "studied," and only 3,000 were accepted by the commission. 5,000 women have applied for the benefit and will be given priority, according to GADEM Secretary-General Hicham Rachidi. The program will end on December 31 of this year. Human rights and migrant associations have expressed their criticism of the process, including concerns with procedural matters like the length of time it takes to make a status determination, the strict criteria for legal residence, and the short-length of residency permits.
Despite the platform's reforms, civil society groups in Morocco, which specialize in the area of migration and asylum, continue to fill the vacuum left by the government. Without proper legal institutions, the right to legal assistance, including the right to appeal, as well as access to interpreters, social aid, and psychological support, would not be provided to applicants but for the efforts of these organizations.
Morocco's domestic and international human rights commitments in the area of asylum and migration are generally progressive—the problem is one of implementation, institutional development, and empowerment of democratic institutions. It also cannot be forgotten that the process is presided over by a royally supported institution—the National Human Rights Council. This appears to affirm the continuing power of political co-optation, demonstrating that the reform process poses no real ideological, political, or economic threat to the status quo.
[1] Willis, Michael, Politics and Power in the Maghreb: Algeria, Tunisia, and Morocco from Independence to the Arab Spring, (Hurst and Company, London, 2012), 140-146.
[2] Khachani, Mohammed, Les Marocains et Les subsahariens: Quelles relations?,(Moroccan Association for the Study and Research on Migrations, 2009), 26, 33, 37, 40, 42.
By: Anna Jacobs
Copyright © 2010-2014 Muftah. All rights reserved.
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text:
complacent (about somebody/something) (usually disapproving) too satisfied with yourself or with a situation, so that you do not feel that any change is necessary; showing or feeling complacency a dangerously complacent attitude to the increase in unemployment We must not become complacent about progress. Word Origin mid 17th cent. (in the sense 'pleasant'): from Latin complacent-adjectivejump to other results
BrE BrE//kəmˈpleɪsnt//; NAmE NAmE//kəmˈpleɪsnt//
Check pronunciation: complacent


text:
If the Beastie Boys woke up one morning and decided they were an indie folk band, you'd probably have the Kinetic Stereokids. Every so often some of that rap precociousness would spill over and the pull to experiment would be stronger than any force life ever imagined.
'Course, Kinetic Stereokids are no Beastie Boys. And, by god, they don't hafta be, now do they?
They are a committed, entertaining, enchanting Michigan-based outfit drawn from basement rock-out sessions among friends. Comparisons to the aforementioned Beasties, Can, Elliott Smith, Mogwai, Beck, and so forth abound and are reinforced within seconds of listening to Kid Moves, the band's second album.
Naturally, the Kinetic Stereokids infuse the music with their own misshapen sense of things and cleverly create their own identity – or lack thereof.
Kid Moves opens up with a rollicking jam tinged with electric guitar and beats to die for. "Free Money" has a great summertime appeal, bouncing and whistling with a happy melody and likeable vocals. The abrupt drops of feedback and the howling, crusty guitar solo drilling away helps accent the reality that this is no ordinary indie folk shit and that Kinetic Stereokids are no ordinary band.
At times, the samples and distorted radio fuzz can get a bit dizzying. The songs are often noisy and often busy, leading to a sort of obnoxious sonic alchemy that takes a bit of getting used to. There's a lot going on within the background of a typical tune, to be sure, but there's also a helluva lot to like.
Banjo and acoustic guitar meld together for "Have a Nice Day," kicking off a decent folk piece. A deformed, rough-sounding violin highlights the musicianship these guys are capable of, adding to an Americana vibe.
This album was built with the intention of creating a folk music tableau and slathering it with sloppy nacho-cheesy haze. "Kid Moves was originally conceived as being a project in which we would create these very delicate, almost baroque folk songs and alter them to the point of disfiguration," frontman Justin Ford told quietly loud.
The near-8-minute "Planes with Teeth" brims with that sort of disfiguration. Starting off with a divine groove, the track uses incongruous vocals, scratches, stacks of samples on top of stacks of samples, rap, clattering acoustic, and anything else these experimenters can think off to push the limits of song construction. It's either spectacular or completely horrific.
And that's just it: these songs are ditheringly beautiful, confusingly resolute, absurdly uncomplicated. Their style brims with modish musical conundrums, bowling strikes with sample-heavy grit and filthy poppish folk to the point of being utterly, explicitly unclear. Confused? You better be.
Whether rolling through a sort of surplus sound necropolis ("Proper Etiquette") or attempting a Mellow Gold-era Beck vibe with "Twisted Thoughts," these Kinetic Stereokids are serving the Master of Disfigured Jams with reckless abandon. One of the boldest, grittiest, weirdest records I've heard so far this year, Kid Moves is chic junkyard scrap.Powered by Sidelines


text:
48 E Willow Street,Elizabethtown PA, 17022
3,819 sq. ft
Status: Active
Last Updated: 2/25/2017 2:11 PM
Description for 48 E Willow Street Elizabethtown, PA 17022
4 Unit Apartment building and a Carwash. 1 Automatic touchless bay, 3 self serve bays and 1 pet wash. All units currently rented and carwash is fully functional. Property has potential for significant increase in cash flow.
Listing Information
Electric Water Heater, Gas Water Heater, On Site,
Public Sewer
220v Service, Cable TV, Electric, Natural Gas, Sewer, Water
Apartment Building,Automotive,Car Wash,Commercial,
School Information
Room Information
Interior Features
3,819 Sq. Ft. Above Ground
Window/Wall Unit
Exterior / Lot Features
On Site
151x60x49x95x103x152, .25 Ac to LT .50 Ac
In City, City Road, Level
Financial Considerations
Inside AccessTM
Current market conditions for 48 E Willow Street
Active Market Trends
Source:MLS DATA
Median list price$239,900
Days on market116
Properties for sale127
Sold Market Trends
Source:MLS DATA
Median sold price$184,750
Sales to list price9,693.0%
Properties sold84
Median sq ft price$117
Arrows indicate 90 day trend
Listing Price History for 48 E Willow Street
Elizabethtown Real Estate
Elizabethtown is located in Pennsylvania. Elizabethtown, Pennsylvania 17022 has a population of 11,579.
The median household income in Elizabethtown, Pennsylvania 17022 is $50,443. The median household income for the surrounding county is $56,172 compared to the national median of $53,046. The median age of people living in Elizabethtown 17022 is 31.8 years.
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text: Original LeBron Hater Sick Of All The Bandwagon HatersTom Ley4/24/14 1:56pmFiled to: funnylebron jamesmatt liebsatirethings we actually likenba2616EditPromoteShare to KinjaToggle Conversation toolsGo to permalink This right here is a brilliant piece of satire. Comedian Matt Lieb adopts the character of someone who has been hating LeBron James way before you were hating LeBron James, and in the process captures everything that is annoying about scolding fans who never shut up about bandwagoners. There's also a pretty great drawing of LeBron imagined as a penis.Reply26 repliesLeave a reply


text:
Jumbo Fluke with Pea Puree Sauce and Veggies
|Flounder fillet
|3 1⁄2 Pound
|Wild spring onion/Scallion
|2 Tablespoon, cut roughly
|Baby fennel leaves
|2 Tablespoon, cut roughly
|Fava beans
|2 Tablespoon, cut roughly
|Spring peas
|3⁄4 Cup (12 tbs) (2 cups for puree)
|2 Tablespoon, diced
|1 Teaspoon
|1 Teaspoon
|Chicken stock
|3 Tablespoon
|Garlic cube
|1 (Dorot brand, equivalent to 1 minced garlic)
|1⁄2 Cup (8 tbs), sliced thinly
|Chanterelle mushroom
|1⁄2 Cup (8 tbs), halved and diced
|Shitake mushrooms
|1⁄2 Cup (8 tbs), halved and diced
|Rampe leaves
|2 Tablespoon, chopped roughly
|Minced basil cube
|1 (Dorot brand, equivalent to 1 teaspoon minced basil)
|Truffle oil
|1 Teaspoon
|Curry powder
|1 Teaspoon
|Thyme leaves
|2 Medium
|1 Medium
|Extra virgin olive oil
|1 Teaspoon
1. In a pan heat oil and saute baby fennel bulbs, fava beans, spring peas, tomatoes chopped, salt and pepper.
2. Add 1 Dorot garlic cube and continue to cook.
3. In another pan, saute thin shallot slices and chanterelle mushroom pieces for a while.
4. Add herbed butter (with parsley and chives) and stock and cook.
5. Stir in shitake mushrooms, rampe leaves and 1 cube minced basil and cook.
6. Season the filets with salt and pepper and dust with flour.
7. In a pan heat 4 tablespoons oil and brown the fish filets until lightly golden brown.
8. Squeeze over lemon and add thyme.
9. To make peas puree, boil peas in water until done, drain completely, blend in a blender and season with truffle oil and curry powder.
10. On a serving plate make a bed of sauted vegetables, top with a fish filet and then top with sauted mushrooms.
11. Spoon over seasoned pea puree and extra virgin olive oil and serve.
Recipe Summary
Rate It
Nutrition Rank
Nutrition Facts
Serving size
Calories 355 Calories from Fat 141
% Daily Value*
Total Fat 16 g24.1%
Saturated Fat 5.8 g28.9%
Trans Fat 0 g
Cholesterol 112.2 mg37.4%
Sodium 871.9 mg36.3%
Total Carbohydrates 26 g8.6%
Dietary Fiber 4.5 g17.9%
Sugars 7.7 g
Protein 29 g57.1%
Vitamin A 13.4% Vitamin C 32.5%
Calcium 9% Iron 11.3%
*Based on a 2000 Calorie diet


text:
Dragon Claw, intersectional 'Itoh' peony
Notable characteristics: Small, very dark maroon flowers resemble those of the tree peony species P. delavayi. Those familiar with the wild trilliums of the woods of New England will recognize this shade of dark maroon red. This semi-dwarf hybrid peony is offered exclusively by Cricket Hill Garden.
Cultivar group, hybridizer and year introduced: Intersectional peony, Frank Simone, early 1990s.
Growth habit and size at maturity (10 years old): Spreading, grows to 2' tall and 3' wide.
Flower form and size: Single form blossoms, 3-4" and upward facing. Flowers held well above the foliage.
Flower fragrance: Light, spicy.
Bloom time: Early season 'Itoh' intersectional hybrid peony, blooms in our USDA zone 6a garden in the last week of May and first two weeks of June. Long blooming cultivar.
Zone hardiness: Proven in USDA zones 4-9.
Plant size: 4-5 'eyes' ( buds) with a well developed root system. This size plant will most likely flower its first or second spring in the ground.
When we ship: USDA Zones 4-9 ship in early spring, 2017.


text:
I was very happy the K. family was up for where we chose to have our family shoot. St. Vincent's is one of the most beautiful and peaceful locations I've visited since moving to Marin. And it's just minutes off of Highway 101 in San Rafael. Located on 780 acres, the Spanish colonial-style buildings surrounding the lovely chapel give you a real sense of California history. It's feels as if you are stepping back in time. Originally built as a school by the Dominican Sisters in 1855, the campus was rebuilt and expanded by the Christian Brothers in the 1920's. The sprawling Mission-style campus is the perfect backdrop for a family photo session with white walls and red stone steps surrounded by a grove of eucalyptus trees. Add to that a ballet school housed on the grounds with classical music emanating from the open windows and it truly felt magical.
In Category: 'Children'w
Corte Madera Family Session
Lafayette Newborn Session
First newborn session of 2016! Such a great way to kick off the new year. Baby B. was born on Christmas Eve and I loved photographing all the new relationships his arrival creates with mom, dad and big brother. Thank you N. Family!
Larkspur Family Session
The B. Family was the successful bid on an auction item I donated to the Twin Cities Coop Preschool in Corte Madera. We had a beautiful September evening on the beach for our family photography session. The three girls brought so much fun energy to the session and I loved capturing their interactions. Thank you B. Family!
Stinson Beach Family Session
On a hot July day, with a high of 99 degrees, we headed to Stinson Beach for some cooler breezes and beautiful light. The W. Family was the successful bid this year on an auction item I donated to the Ross Valley Nursery School in Kentfield. I love how the family's outfits coordinate so well with the natural beach colors! Photography enables me to meet so many nice Marin families. Thank you W. Family!
Kentfield Newborn Session
The H. Family welcomed a new baby boy last week. It was such a treat to capture this truly joyful occasion. Thank you H. Family!
London with Younger Children
This is the start of a new column on Travel with Children. First destination: London, specifically with younger children. Having lived in London for three years with a toddler I am often asked for suggestions on fun family activities for visitors. London is a fantastic city to visit with young children. There are unlimited castles, towers, museums and parks. Just riding on the double-decker buses (be sure to sit upstairs!) or in the black cabs would probably bring hours of pleasure for any young child. But there are so many fun stops to make along the way. In addition to the obvious sites to visit, such as Buckingham Palace, here are some of our favorite activities when we lived as locals. Some favorite activities: The Serpentine Lido at Hyde Park: you pay a nominal entrance fee and have access to a lovely elevated spacious grass area with paddling pool, playground and sandbox
Greenbrae Newborn Session
Another lovely newborn session in Greenbrae. Big sister was so happy to welcome her new baby sister. Those first few days are truly magical.
Mill Valley Newborn Session
Oh the excitement of a new baby in the family! Miss A. is just 8 days old and her big sister, parents and grandparents are so happy to welcome her. Thank you B. Family for such a relaxed morning session.
Family of 6 in Tiburon
Tiburon truly felt like the great small town that it is when we had our session there this week with this family of six. I'm sure for the P. Family it feels completely normal to have so many residents stop to speak to them. For me, it was really fun to observe. I think my favorite interaction was when the bus driver slowed down his bus to hold up 4 fingers and then gave a big thumbs up. We had beautiful light in the late afternoon and the children were so much fun to photograph. Thank you P. Family!
Inverness Family Session
We had a beautiful fall afternoon in Inverness on Tomales Bay this past weekend. And all wrapped up in time to watch the World Series. Thank you S. Family for making the session such a breeze!


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Style your casual wardrobe with the EA7 ID jogging shorts. Crafted from pure cotton, this piece is finished with two front pockets and the brand's iconic logo printed down the left leg.
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A bladder tumor is an excessive reproduction of cells that line the bladder where liquid waste from the kidneys is stored in the body until released through urination. Most tumors are noncancerous wart-like growths called papillomas. Cancerous bladder tumors can spread through the bladder wall and into other organs via the blood stream.

Bladder tumors are nearly four times more common in men than in women.

Bladder tumors are most common in white men over the age of 50.

Less than 1 percent of cases of bladder cancer occur in people under 40 years old.

Bladder tumors are the second most common tumor that can occur in the reproductive and urinary tract (a prostate tumor is the most common).

Tumors of the lining of the bladder cause about 4 percent of all cancers diagnosed in the United States.

Bladder tumors can be cancerous or noncancerous (benign).

Causes of Bladder Tumors

Causes of bladder tumors can include exposure to carcinogenic chemicals—chemicals that are known to cause cancer and include chemicals used in the rubber and dye industries—smoking tobacco, chronic urinary tract infections, and schistosomiasis, a parasitic infection common in the tropics.

Signs and Symptoms of Bladder Tumors

The signs and symptoms of bladder tumors can include the following:

Blood in the urine. This symptom is very common in bladder cancer

A sudden feeling that you urgently need to pass urine

An increased frequency in the feeling that you need to pass urine, often with the passing of smaller amounts of urine

Back or abdominal pain

 Appetite loss and/or weight loss

Most bladder tumors are painless. Signs and symptoms can and do vary depending on the type of bladder tumor, size, and spread of the disease.

Bladder Cancer

As many as 77,000 Americans are diagnosed with bladder cancer each year, and each year bladder cancer claims 16,000 lives in the U.S.

The majority of bladder cancers begin in the urothelium or transitional epithelium, which is the innermost lining of tissue in the bladder. These cancer cells are referred to as non-invasive. Cancer cells that are invasive grow into deeper layers of the bladder wall and beyond the bladder into surrounding areas, including the lymph nodes, making cancer more difficult to treat.

Bladder cancer cells (whether invasive or non-invasive) that have not grown into the muscle tissue of the bladder may also be referred to as non-muscle invasive or superficial.

The most common form of bladder cancer is known as urothelial carcinoma or transitional cell carcinoma (TCC). Because urothelial cells are common throughout the urinary system, such as in the urethra and the tubes connecting to the kidneys, tumors may exist in these other places as well and the entire urinary tract should be checked if tumors are found.

Bladder Cancer Survival Rate

Cancer survival rates can be confusing and even dire, but they are often misinterpreted. The five-year survival rate for those treated for bladder cancer varies depending on the stage of the cancer being treated. The following percentages represent patients who survive at least five years after diagnosis; however, these are not predictive of how long a person will live after being diagnosed—many people survive well beyond the five-year measure used—but the numbers can help gauge how effective treatment may be.

Stage 0: 98 percent

Stage I: 88 percent

Stage II: 63 percent

Stage III: 46 percent

Stage IV: 15 percent

More Information

About Bladder Cancer


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Archive for the 'Kaiser Chiefs' Category
AWmusic's Top Songs of 2008 pt 2: #51-75
I forgot to mention that these top songs are still very personal opinions despite trying to take as many suggestions of the rest of the writers. I'm not sure how people will respond to the list, numbering isn't quite as important as inclusion. I like taking suggestions as there will be millions of tracks I likely missed. As is the goal with this list, 10-limit descriptions included.
Next in the series:
Part 3: #26-50
Part 4: #1-25
Numbers #51-75:
#51 Creator by Santogold w/ Switch and Freq Nasty (myspace/video -unofficial was canceled?)
The intro is risky, brave and wildly effective.
#52 Crystal Stilts by Crystal Stilts (myspace)
A song should be good if it's your band name.
#53 I Wish I Could Keep You by Little Pictures (myspace/live)
This song makes me wish I was a kid again.
#54 In The Kitchen by The Pomegranates (myspace/live -poor visual quality)
A song I want to play on the guitar.
#55 Never Miss A Beat by Kaiser Chiefs (homepage/video)
The kids on the street, are scary! Shiiet.
#56 Death To The Los Campesinos! By Los Campesinos! (myspace/video)
"I'll be control-alt-deleting your face with no reservation".
#57 Marry Me Annie by Matthew and The Arrogant Sea (myspace)
Hey Annie, I'm serious, MATAS is a great band.
#58 Whiite Fantaseee by Slim Twig (myspace)
How about an Asian fantaseee?
#59 Dance Dance Dance by Lykke Li (myspace/live with Bon Iver)
Lykke Li's hips lie and she's shy. I'm in love.
#60 Galaxy Of The Lost by Lightspeed Champion (myspace/video)
Emmy The Great makes this song gold. Weird video.
#61 Skinny Love by Bon Iver
Bon Iver should try BBW. Morbidly Obese Love anyone?
#62 Good Time by Brazilian Girls (myspace/video)
I just want to have a good time too.
#63 Can't Shake It by Kate Miller-Heidke (myspace/video)
I can't dance either though this song is danceable…
#64 New Soul by Yael Naim(homepage)
I'm a new ipod product with a new catchy song.
#65 Boneless by The Notwist (homepage)
Great song off a slightly disappointing album.
#66 Shadow Falls by Hello, Blue Roses (myspace/live)
Awesome duet, too bad they were bashed by Pitchfork.
#67 Get Better by Mates of State (myspace/video)
"Forget your politics for awhile". 2008 was a tough year.
#68 Xavia by The Submarines (myspace)
The Submarines don't let me down in this song.
#69 Home Sweet Home by Those Dancing Days (myspace/video)
A perfect holiday song.
#70 Not Your Savior by Peasant (myspace)
Peasant keeps it honest, leave him alone.
#71 Call It A Ritual by Wolf Parade (myspace)
I enjoy Spencer Krug's metaphorical writing.
#72 Black Rice by Women (myspace/live)
Best Song that ends in a whimper.
#73 The Rip by Portishead (homepage/video)
Just beautiful.
#74 That's Not My Name by The Tings Tings (myspace/video)
Wait..what is her name again?
#75 Gila by Beach House (myspace/live)
Kaiser Chiefs – Off With Their Heads Review
The Kaiser Chief's third album, Off With Their Heads went to number #2 on the UK charts in terms of sales. They've been a mainstay since their debut release Employment which was an album I liked quite a bit and still listen to once inawhile. However, their second release, Yours, Truly Angry Mob definitely disappointed me (and that one went #1) and was a big step back.
I wasn't sure what to expect since the Chiefs were in limbo of having me as a fan. As popular as Mark Ronson is, he's doesn't exactly instill some respect nor do I care who's doing the producing. However, initial listens were very good. I was specifically addiction to the track "Never Miss A Beat" before finding out that it was the albums first single. A lot of the album is catchy, which isn't a surprise considering the Kaiser Chiefs past tracks. On the first few listens, I was about to sing my praises on how good this album is. They do have different approaches to satisfy what makes a good pop song and almost each song on its own at first glance comes off as sounding pretty good.
That explains a lot of the positive reviews, HOWEVER this album does poorly when it comes to replay value. It went really downhill after the 5th listen on, for comparison sake it's very similar to Employment but this album got me a lot more bored. Part of the problem in my opinion is that when repetitive lyrics don't have the qualities of becoming some sort of anthem (like most of the songs on Employment) a lot of these songs become dull very quickly.
I think that's ultimately the case. The Kaiser Chiefs don't bring that much to the table and are a very mainstream band so they have to be spot on when it comes to their execution. It works at first and does work for a few tracks, like Remember You're A Girl and the aforementioned first hit but there's got to be a reason why I can't really listen to much else.
Rating: 3 out of 5
A lot of potential hits here but as an album, it's difficult to listen to now and that's a pretty important quality. In some cases I would say that the Kaiser Chiefs have returned to what made them great but there's still something missing. It might be due to the lack of range when it comes to singing and overall variety of sound.
Never Miss A Beat by Kaiser Chiefs
Back 2 School/End of Summer Playlist
Summer has basically ended with me wasting it and not working all. My summer ended in July as I injured my knee and wasn't really able to have fun for the last month. I'll try… to go back to some concerts but standing around is still a bitch.
Filling in for Joe who needs a break before school starts, I'm holding onto the albums I review for tomorrow 😉 so enjoy this playlist. Most of them are recycled MP3s from other posts and rather short songs but it's better then nothing right?
Constructive Summer by The Hold Steady – We've had a constructive summer for this blog didn't we?
Stuck For The Summer by Two Hours Traffic – I was stuck at home for a good 5 weeks
It's That Time Again by The Dodos
Brain Burner by No Age
Learnt My Lesson Well by Kaiser Chiefs
We'll Never Sleep (God Knows We'll Try) by Rilo Kiley
Insane Ft. Warrior Queen by The Bug
This Is Not A Test by She & Him
It Could Have Been A Brilliant Career by Belle and Sebastian -They'll be saying that about me when I spend more time on this blog then on actual school
Holiday by Chaingang – hopefully you enjoyed your labor day!
The Dark Knight Playlist and Review
I dislocated my knee Thursday night so all I've got to do is stay at home on my bed. I figured I'm about a week late with the playlist and review, who needs my input? With the extra time "presented" to me, I changed my mind. It also "puts a smile on my face"
The Dark Knight has been a huge critical and financial success, grossing just under $160 million in an opening weekend, critical praise of 95% and becoming the #1 movie on IMDB. So better late then never with my review and playlist?
My playlist tried to involve some key quotes surrounding the movie. Granted the real soundtrack is great but let's give the movie a good playlist anyway.
1. The Thieves They Are Everywhere by Bridges and Powerlines
2. Pencil Rot by Stephen Malkmus
3. Only Clowns Are Scary by I Love Math
4. Boy With A Coin by Iron & Wine
5. Smile Like You Mean It by The Killers
6. Knights of Cydonia by Muse
7. I'm Your Villain by Franz Ferdinand
8. The Angry Mob by Kaiser Chiefs
9. Psycho Killer by The Talking Heads
10. No Key, No Plan by Okkervil River
11. Black Heroes by Ratatat
Here's the movie review below (CONTAINS SPOILERS!!!!!!)
Indie Playlist for UFC 83 St. Pierre vs Serra
UFC 83 is happening this Saturday at the Bell Centre in Montreal. Canada's first UFC event which I will be catching with some friends and I have to get this out of the way since I won't be posting for a week (exams!).
I'm pretty excited and I hope MMA finally gets approved in the province of Ontario so we can get a event here in Toronto. Either way, I hope UFC comes back soon. I'll be making picks in addition to having a tribute mp3 to the main card fighters.
Georges St. Pierre vs. Matt Serra
1. Midnight Surprise by Lightspeed Champion
-Can Matt Serra pull off the 2nd upset?
2. Frenchy's By Holy Fuck
-Calling GSP Frenchy insulted him big time
3. Home Field Advantage by Drive-by Truckers
4. If I Faltered Slightly Twice by Of Montreal
-Georges is too good, everyone or almost everyone has St. Pierre taking this one easily. When the pressure is on GSP performs.
Winner: Georges St. Pierre in 5 round round war. I love Matt Serra as well to be honest and he has world class skill and will frustrate St. Pierre at times. It may be boring….
Michael Bisping vs. Charles McCarthy
5. Sing! Captain by The Handsome Furs
– For Charles "Captain Miserable" McCarthy
6.Everything is Average Nowadays by the Kaiser Chiefs
-For Michael Bisping getting mad that McCarthy called him average, such a huge insult.
Winner: Bisping by 2nd round TKO. Rooting for McCarthy though.
Rich Franklin vs Travis Lutter
7. Don't Weigh Me Down by Broadcast 2000
– Lutter better make weight, he didn't against Anderson Silva when he had a title shot on the line.
8. Can't Lose by We Are Scientists
Franklin's career can probably take only one more loss.
Winner: Travis Lutter by Armbar in Round 3. Picking an upset here.
A pretty weak card but I'm going to see this one anyway because it's in Canada. The Montreal crowd should make this an event to watch (I envy their atmosphere).


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Printer Sales, Service and Supplies
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Lots of promise and lots of promises.
Having attended the "world launch" today it seems that they are still not for sale and the Australian distributor (Zolar Distributors) dose not have a street address.
It is claimed that the SunCube can deliver electricity at a cost similar to conventionally produced electricity.
Without any performance figures or prices it is very difficult to analyse this claim.
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Where London had G4S, Sochi had G-A-Y. Rows that dominate the build-up to an Olympic Games rarely come to overshadow them, even though Sochi's was rather more serious than London's – a sovereign nation persecuting a large section of its own people, as opposed to a cocked up contract with a private security firm.
But it meant that the casual observer found out very little about what to expect from an Olympics in a town they'd never heard of, in a difficult region of a confusing country. But two weeks on, as the Closing Ceremony's curtain fell last night, the Sochi Games have charmed and mystified audiences in equal measure. So what have we learned?
Violinists do not make good skiers
Type Vanessa Mae into Google and you'll quickly find out she is a British-Singaporean violinist, which does little to explain quite why she has been slaloming down the Sochi mountains in the colours of Thailand. She also had to change her name to Vanakorn, that of her Thai father's. She came last in the women's downhill and by some margin. She was also, at 35, the oldest competitor, also by some margin. But she is no gallant Olympic failure, like the Jamaican bobsled team, or Eddie "the Eagle" Edwards. She trained for just six months, and her aim was to "not get lost". She didn't, alas, but had she done so, no one would have been getting their violins out.
Life's still tough for girl bands
You turn up, you put on your luminous balaclava and start to sing. Then you get pepper sprayed and whipped by a cossack. It came as no surprise to see the newly unimprisoned Russian protest punk act Pussy Riot turn up at the Games with politics on their minds, but the pictures that emerged of two of their number being attacked by Russian security forces were still extremely shocking. Two of them were later arrested on suspicion of stealing a woman's handbag. It's as true as ever, that if you want to protest successfully at the Olympics, you've really got to win a medal first.
Russia CAN throw a party
Well, kind of. It certainly looks incredible on the television, the medal plaza packed at night in that central square surrounded by five stunning stadiums. But, whisper it, there's not that many people around. Sochi is a town of 300,000 people, the Olympic Park isn't even in the main part of it and it's still a two-hour flight from Moscow and three from St Petersburg. Most of the volunteers were flown in and almost none of the events have been full. Those who are there are doing an impressive job of looking happy. The McDonald's didn't get built in time, leaving Olympic attendees with almost no dining options beyond the now infamous Sochi Hot Dog, which comes slathered in a cheese sauce so astringent it could replace soap and water as a punishment for vituperative children.
The hills are alive with the sound of woofing
In a tale of schmaltz that goes up to 11 and far beyond, when stories emerged in the days before the Games of a mass stray dog cull, a hero emerged, and he just so happened to be the coolest man on the planet. Gus Kenworthy, 22, an American wearer of back-to-front baseball caps, will not only be taking the silver medal for slopestyle skiing home with him, but no fewer than four stray puppies and their mother. He and his little doggies have become something of a social-media sensation. Now Slovenian ice-hockey players, American snowboarders and skaters are all getting in on the act. Forget Malawian babies, a Sochi stray is the new must-have animal accessory.
Not everyone's feeling the love
If canine love is in the mountain air, it has its limits. "All you've got to do is walk in here, look a bit glum and it's green-card city, Illinois," is what the giant wolf that wandered into the athletes village must have been thinking. But it didn't work. US luger Kate Hansen hid behind her door, terrified, and filmed the great beast wandering the corridors outside. Except, of course, she didn't. The whole thing was a hoax by the US talk-show host Jimmy Kimmel. Privately, apparently, the International Olympic Committee blazerati are amused. President Vladimir Putin has yet to comment.
Britain are still rubbish
Yes, yes, so it's been our most successful Games since 1924, four medals, hooray. We finished above the Italians in the medal table, despite their ready access to the Alps. But there are no longer excuses to be made. Much has been made of the heat of Sochi – ice-skating below the palm trees and so on – and it's true. Forget mountains, sports on rinks can be done anywhere. There are ice-hockey teams all over America's south. The Netherlands, a country and a people disarmingly similar to us, have won six golds in speed skating, purely because they've decided to take it seriously, as the Brits have been doing with other sports. Let's have a proper go.Reuse content


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Tennessee Hall of Shame
www.flpba.org [cached]
The warden who was dismissed was Alan Bargery and the security chief was Glenis Henson.
The warden who was dismissed was ...
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The warden who was dismissed was Alan Bargery and the security chief was Glenis Henson.
News Channel 9: Silverdale Warden Fired for Poor Recordkeeping
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CCA, which operates the workhouse, says such poor record keeping is a violation of company policy.
Administrative Changes Welcome at Silverdale - News 12 Chattanooga
www.wdef.com [cached]
CCA's policy says all drugs taken from inmates must be documented and turned over to the Hamilton County Sheriff's Department.Silverdale's officers could not produce any list of drug seizures after the county requested one.> >
News Channel 9: The Cost of Inmate Care
www.newschannel9.com [cached]
That policy is echoed by Hamilton County Executive Claude Ramsey. 'I don't know that it is writen anywhere but if the warden were to call me while we were sitting here and say I have got a sick prisoner where should I take him to the hospital?
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Bonnie Raitt's first video in 14 years is a simple, straightforward clip. Footage of the guitarist performing the Gerry Rafferty tune "Right Down the Line" is cut with images of loving couples filmed at the abandoned Mission Theatre in San Francisco.
Bonnie Raitt 'Right Down the Line'
'Right Down the Line' from the guitarist's new record 'Slipstream'


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Image 7-292-3 | Photo ©David Sanger | India, Rajasthan, Sariska Palace Hotel
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|Jump to ...
|Graduate Students
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Graduate Students
Jonathan Cooper – Cancer Biology
Education B.S. – Biology, 2010, Dallas Baptist University
Research Interests: Exploring the intersection between cellular growth and renewal signaling pathways and their dysregulation in cancer. Specifically, I am interested in investigating the key players in cellular responses to nutrient availability and probing for selective vulnerabilities in cancers harboring aberrant nutrient sensing.
Cooper, J. M., Bodemann, B. O., and White, M. A. (2013). The RalGEF/Ral pathway: evaluating an intervention opportunity for Ras cancers. The Enzymes 34, 137-157.
Thomas, J.C., Cooper, J.M., Clayton, N.S., Wang, C., White, M.A., Abell, C., Owen, D., and Mott, H.R. 2016. Inhibition of Ral GTPases Using a Stapled Peptide Approach. Journal of Biological Chemistry, in press.
Elizabeth McMillan – Cell Regulation with Supplemental Curricula in Computational, Systems Biology
Education: B.A. – Biology, B.A. – Mathematics, 2011, New York University College of Arts and Sciences/New York University Courant Institute of Mathematical Sciences
Research Interests: Oncogenic lesions arising during cancer progression provide an attractive target for chemical intervention strategies. The extreme molecular heterogeneity of tumors, however, makes it difficult to identify authentic intervention targets and to link patients to the most appropriate treatment. To confront this challenge, we launched a full scale investigation to identify the genetic lesions that arise during cancer progression together with a computational approach to link novel compounds to these lesions. A panel of 103 non-small cell lung cancer cell lines was screened with over 200,000 uncharacterized synthetic chemical compounds and natural products fractions in a tiered HTS approach. Statistical and machine learning procedures were then used to link drug activity to the complexity of cancer genomes by systematically assigning enrollment biomarkers to each compound from measures of gene expression, gene mutation, gene copy number, protein expression, and metabolomics datasets. Using this approach, we have found that genetic vulnerabilities that are not currently actionable can be linked to novel chemicals. Experimental mechanism of action hypotheses can be derived from these chemical/biomarker relationships and were validated for a subset. Notably, we are able to parse KRAS mutant cancers into multiple, distinct molecular subtypes defined by co-occurring mutations. This indicates that KRAS lung cancers are representative of diverse mechanistic subtypes, and we are able to identify putative novel compounds that may target each subtype. Collectively, we are using this approach as a data driven way to parse mechanistic cancer subtypes and identify a diverse cohort of therapies capable of contending with cancer heterogeneity together with enrollment biomarkers that can specify sensitivity.
Ekas, L. A., T. J. Cardozo, M. S. Flaherty, E. A. McMillan, F. C. Gonsalves and E. A. Bach (2010). "Characterization of a dominant-active STAT that promotes tumorigenesis in Drosophila." Dev Biol 344(2): 621-636.
Kim, H. S., S. Mendiratta, J. Kim, C. V. Pecot, J. E. Larsen, I. Zubovych, B. Y. Seo, J. Kim, B. Eskiocak, H. Chung, E. McMillan, S. Wu, J. De Brabander, K. Komurov, J. E. Toombs, S. Wei, M. Peyton, N. Williams, A. F. Gazdar, B. A. Posner, R. A. Brekken, A. K. Sood, R. J. Deberardinis, M. G. Roth, J. D. Minna and M. A. White (2013). "Systematic identification of molecular subtype-selective vulnerabilities in non-small-cell lung cancer." Cell 155(3): 552-566.
Osborne, J. K., M. L. Guerra, J. X. Gonzales, E. A. McMillan, J. D. Minna and M. H. Cobb (2014). "NeuroD1 mediates nicotine-induced migration and invasion via regulation of the nicotinic acetylcholine receptor subunits in a subset of neural and neuroendocrine carcinomas." Mol Biol Cell 25(11): 1782-1792
Borkowski, R., Du, L., Zhao, Z., McMillan, E., Kosti, A., Yang, C., Suraokar, M., Wistuba, I., Gazdar, A., Minna, J., White, M.A.* and Pertsemlidis, A.*. 2014. Genetic mutation of p53 and suppression of the miR17~92 cluster are synthetic lethal in non-small cell lung cancer due to upregulation of vitamin D signaling. Cancer Research in press. *co-corresponding authors.
Witkiewicz, A.K., McMillan, E.A., Balaji, U., Baek, H., Lin, W., Mansour, J., Mollaee, M., Wagner, K., Koduru, P., Yopp, A., Choti, M., Yeo, C.J., McCue, P., White, M.A., and Knudsen, E.S. 2015. Whole exome sequencing of pancreatic ductal adenocarcinoma reveals hallmarks of disease etiology, prognosis, and targets for therapeutic intervention. Nature Communications 6:6744.
Potts, M.B., McMillan, E.A., Rosales, T. I., Kim, H.S., Ou, Y.H., Tooms, J.E., Brekken, R.A., Minden, M.D., MacMillan, J.B., and White, M.A. 2015. Exceptional responders to dedemnin B illuminate the mechanism of action and pharmacogenomics biomarkers for antineoplastic activity. Nature Chemical Biology
McNamara, R.P., Reeder, J.E., McMillan, E.A., Bacon, C.W., McCann, J.L., and D'Orso, I.D. KAP1 recruitment of the 7SK snRNP complex to promoters enables transcription elongation by RNA Polymerase II. (2015) Molecular Cell (in press)
Shields, B.B., Pecot, C.V., Gao, H., McMillan, E., Potts, M., Nagel, C., Purinton, S., Wang, Y., Ivan, C., Kim, H.S., Borkowski, R. J., Khan, S., Rodriguez-Aguayo, C., Lopez-Berestein, G., Lea, J., Gazdar, A., Baggerly, K.A. Sood, A.K., and White, M.A. 2015. A genome-scale screen reveals context-dependent ovarian cancer sensitivity to miRNA overexpression. Molecular Systems Biology, 11: 842.
Young, J. H., Peyton, M., Kim, H., McMillan, E., Minna, J. D., White, M. A., and Marcotte, E. M. 2016. Computational discovery of pathway-level genetic vulnerabilities in non-small-cell lung cancer. Bioinformatics, in press.
Hensley, C.T., Yuan, Q.Y., Lev-Cohain, H., Kim, J., Liang, L., Eunsook, J., Skelton, R., Loudat, L., Wodzak, M., Cai, L., Klimko, C., McMillan, E.A., Butt, Y., Torrealba, J., Malloy, C., Kernstine, K., Leninski, R.E., and Deberardinis, R.J., (2015). "Heterogeneous glucose metabolism within and between human non-small cell lung tumors". Cell (in press)
Chensu Wang – Biomedical Engineering
Education: B.S. – Biomedical Engineering, 2011, Southeast University, Nanjing, China
Research Interests: The interface between engineering and biology; in particular the design and development of nanotechnology tools that illuminate dynamic cell biological processes in space and time. My current project is the application of novel pH-responsive nanoprobes for analysis of autophagosome biogenesis at single organelle resolution. (Joint student with Professor Jinming Gao)
Wang, C., Wang, Y., Li, Y., Bodemann, B., Zhao, T., Ma, X., Huang, G., Hu, Z., DeBerardinis, R.J., White, M.A.* and Gao, J.* (2015). A nanobuffer reporter library for fine-scale imaging and perturbation of endocytic organelles. Nat Commun 6, 8524. *Co-corresponding authors
Dutchak, P.A., Laxman, S., Estill, S.J., Wang, C., Wang, Y., Wang, Y., Bulut, G.B., Gao, J., Huang, L.J., and Tu, B.P. (2015). Regulation of Hematopoiesis and Methionine Homeostasis by mTORC1 Inhibitor NPRL2. Cell Rep 12, 371-379.
Wang, C., Li, J., Amatore, C., Chen, Y., Jiang, H., and Wang, X.M. (2011). Gold nanoclusters and graphene nanocomposites for drug delivery and imaging of cancer cells. Angew Chem, Int Ed 50, 11644-11648.
Thomas, J.C., Cooper, J.M., Clayton, N.S., Wang, C., White, M.A., Abell, C., Owen, D., and Mott, H.R. 2016. Inhibition of Ral GTPases Using a Stapled Peptide Approach. Journal of Biological Chemistry, in press.
Aubhishek Zaman– Cancer Biology
Education: M.S. – Genetic Engineering and Biotechnology, University of Dhaka, Bangladesh
Research Interests: Cancer therapeutics and its mode of actions; key players in cellular growth, vesicular traffic and cellular responses to nutrient availability,.
Publications (selected):
Zaman A* and Razzaque S 'Designing Novel Antibacterials: Application of Omics Science' Klimik Dergisi. 2013; 26; 2-8
Islam MR, Zaman A, Jahan I, Chakravorty R, Chakraborty S*. 'In silico QSAR analysis of quercetin reveals its potential as therapeutic drug for Alzheimer's disease.'J Young Pharm. 2013 Dec;5(4):173-9.
Islam MR*, Hosen MI, Zaman A, Islam MO. 'Structural, functional and molecular docking study to characterize GMI1 from Arabidopsis thaliana.' Interdiscip Sci. 2013 Mar;5(1):13-22.
Zaman A*, Rahaman MH, Razzaque S. 'Kaposi's sarcoma: a computational approach through protein-protein interaction and gene regulatory networks analysis.' Virus Genes. 2013 Apr;46(2):242-54. doi: 10.1007/s11262-012-0865-z. Epub 2012 Dec 25.
Zaman A*, Fancy NN. 'A computational prediction of structure and function of novel homologue of Arabidopsis thaliana Vps51/Vps67 subunit in Corchorus olitorius.' Interdiscip Sci. 2012 Dec;4(4):256-67.
Zaman A*. 'Docking studies and network analyses reveal capacity of compounds from Kandelia rheedii to strengthen cellular immunity by interacting with host proteins during tuberculosis infection.' Bioinformation. 2012;8(21):1012-20.
Islam R, Sakib M S, and Zaman A* 'A Computational Assay to Design an Epitope-based Peptide Vaccine against Chikungunya Virus.' Future Virology. 2012; 7 (10):1029–1042.
Zaman A* (2012) 'Characterization of Coilin protein nucleotide binding region in Homo sapiens' Online Journal of Bioinformatics, 13(2):314-330.
Zaman A* 'Drug Designing Approaches Using In-Silico Techniques' Lambert Academic Press (LAP). 2012; ISBN: 978-3-659-15283-2
*Corresponding author
Postdoctoral Fellows
Rachel Vaden, Ph.D. – Chemistry
Education: B.S. – Chemistry, 2008, University of West Georgia; PhD – Chemistry, 2015, University of Utah
Research interest: The use of molecular tools to probe biological systems can provide insight into complex cellular processes and disease states. My research is focused on understanding how genetic mutations acquired during tumor progression can confer sensitivity to novel bioactive compounds. Not only can these studies facilitate clinical therapeutic development by identifying patient populations that are likely to be sensitive a specific treatment, but they can also provide direct mechanistic information about cancer signaling pathways that may be used to inform additional treatment design strategies.
Vaden RM, Gligorich KM, Jana R, Sigman MS, & Welm BE (2014) The small molecule C-6 is selectively cytotoxic against breast cancer cells and its biological action is characterized by mitochondrial defects and endoplasmic reticulum stress. Breast Cancer Res 16(6):472.
Gligorich KM*, Vaden RM*, Shelton DN, Wang G, Matsen CB, Looper RE, Sigman, MS, & Welm BE (2013) Development of a screen to identify selective small molecules active against patient-derived metastatic and chemoresistant breast cancer cells. Breast Cancer Res 15(4):R58.
Pathak TP, Osiak JG, Vaden RM, Welm BE, Sigman MS (2012) Synthesis and Preliminary Biological Study of Bisindolylmethanes Accessed by an Acid-Catalyzed Hydroarylation of Vinylindoles. Tetrahedron 68(26):5203.
Suzie Hight, Ph.D. – Cancer Biology
Education: B.S. – Biochemistry 2002, University of Iowa; M.S. – Biochemistry and Molecular Biology 2006, Purdue University; Ph.D. – Cancer Biology 2015, University of Texas Southwestern Medical Center.
Research interest: Leveraging the power of functional genomics for identification of new therapeutic strategies to treat cancer. Using functional signature ontology (FuSiOn) mapping, we are elucidating mechanisms of action for bioactive natural products, and thus accelerating the discovery of new therapeutic agents. Also: The role of genetic instability and heterogeneity in tumorigenesis, and strategies for targeting genetic instability in tumors; Identification of synthetic lethal relationships that can be exploited as tumor-specific acquired vulnerabilities.
Caroline Diep, Ph.D. – Cancer Biology
Education: B.A. – Art History 2003, University of Arizona; B.S. – Molecular Cellular Biology 2005, University of Arizona; Ph.D. – Microbiology, Immunology, and Cancer Biology 2015, University of Minnesota.
Research interest: I am interested in identifying and understanding the master molecular drivers and/or regulators of squamous lung carcinoma biology. Insights gained will be leveraged into novel and efficacious therapeutic strategies to precisely treat tumors.
Diep CH, Knutson TP, Lange CA. Active FOXO1 is a Key Determinant of Isoform-Specific Progesterone Receptor Transactivation and Senescence Programming. Mol Cancer Res. Nov 17, 2015. PMID: 26577046
Whatcott CJ, Diep CH, Jiang P, Watanabe A, Lobello J, Sima C, Hostetter G, Shepard M, Von Hoff DD, Han H. Desmoplasia in primary tumors and metastatic lesions of pancreatic cancer. Clin Cancer Res. 2015 Aug 1;21(15):3561-8. PMID: 25695692
Diep CH, Daniel AR, Mauro LJ, Knutson TP, Lange CA. Progesterone action in breast, uterine, and ovarian cancers. J Mol Endocrinol. 2015; 54(2):R31-53. PMID: 25587053
Dressing GE, Knutson TP, Schiewer MJ, Daniel AR, Hagan CR, Diep CH, Knudsen KE, Lange CA. Progesterone receptor-cyclin D1 complexes induce cell cycle-dependent transcriptional programs in breast cancer cells. Mol Endocrinol. 2014; 28(4):442-57. PMID: 24606123
Diep CH, Charles NJ, Gilks CB, Kalloger SE, Argenta PA, Lange CA. Progesterone receptors induce FOXO1-dependent senescence in ovarian cancer cells. Cell Cycle. 2013; 12(9):1433-49. PMID: 23574718
Diep CH, Zucker K, Hostetter G, Watanabe A, Hu C, Munoz RM, Von Hoff DD, Han H. Down-regulation of Yes-Associated Protein 1 (YAP1) expression reduces cell proliferation and clonogenicity of pancreatic cancer cells. PLoS One. 2012; 7(3):e32783. PMID: 22396793
Diep CH, Munoz RM, Choudhary A, Von Hoff DD, Han H. Synergistic effect between erlotinib and MEK inhibitors in K-Ras wildtype human pancreatic cancer cells. Clin Cancer Res. 2011; 17(9):2744-56. PMID: 21385921
Jeon Lee, Ph.D. – Computational Biology
Education: Ph.D. – Biomedical Engineering, 2006, Yonsei University, South Korea; Postdoctoral Fellow, 2013-2014, Johns Hopkins University School of Medicine
Research Interests: Data fusion for anti-cancer drug response prediction, machine learning algorithms for cancer biology and biomedical image and signals, physiological signal analytics, arrhythmia diagnosis and prognosis algorithms, finding links between sleep apnea and arrhythmia, scientific approaches to traditional Korean/Chinese medicine, and clinical trials.
Lee, C. H, Park, K. H, Nam, J. H, Lee, J., Choi, Y. J., Kong, E. J. Son, J. W., Kim, U., Park, J. S., Kim, Y. J., and Shin, D. G (2015). Increased Variability of the Coupling Interval of Premature Ventricular Contractions as a Predictor of Cardiac Mortality in Patients with Left Ventricular Dysfunction. Circulation Journal, 79(11), 2360-2366.
Lee, J., Kim, S. J., Chen, R., and Herskovits, E. H. (2015, August). Brain tumor image segmentation using kernel dictionary learning. In Engineering in Medicine and Biology Society (EMBC), 2015 37th Annual International Conference of the IEEE (pp. 658-661). IEEE.
Kim, J. U., Lee, Y. J., Lee, J., and Kim, J. Y. (2015). Differences in the Properties of the Radial Artery between Cun, Guan, Chi, and Nearby Segments Using Ultrasonographic Imaging: A Pilot Study on Arterial Depth, Diameter, and Blood Flow. Evidence-Based Complementary and Alternative Medicine.
Lee, J., & Finkelstein, J. (2014). Evaluation of a portable stress management device. Studies in health technology and informatics, 208, 248-252.
Lee, J., and Finkelstein, J. (2014). Consumer sleep tracking devices: a critical review. Studies in health technology and informatics, 210, 458-460.
Choi, Y. J., Park, K. H., Lee, C. H., Lee, S. H., Park, J. S., Kim, U., Son, J. W., Lee, J., Kim, J. R., and Shin, D. G. (2014). "Optimal" cutoff value of heart rate; appraisal based on heart rate variability and C-reactive protein. International journal of cardiology, 176(2), 497-499.
Lee, H. K., Lee, J., Kim, H., Ha, J. Y., and Lee, K. J. (2013). Snoring detection using a piezo snoring sensor based on hidden Markov models. Physiological measurement, 34(5), N41.
Lee, J., Song, M. H., Shin, D. G., and Lee, K. J. (2012). Event synchronous adaptive filter based atrial activity estimation in single-lead atrial fibrillation electrocardiograms. Medical & biological engineering & computing, 50(8), 801-811.
Researchers / Staff
Kiran Kaur, Ph.D. – Adjunct Instructor / Lab Manager
Education: M.S., 1982, University of Kentucky; Ph.D. 1994, Southern Methodist University
Saurabh Mendiratta – Research Scientist
Education: M.S. – Biotechnology, 2003, MS University, Baroda, India; M.S. – Cell and Molecular Biology, 2006, University of Texas at Dallas
Research Interests: High throughput SiRNA and chemical compound screening to identify gene targets selectively required for cancer cell survival.
Kim, H. S., Mendiratta S., J. Kim, C. V. Pecot, J. E. Larsen, I. Zubovych, B. Y. Seo, J. Kim, B. Eskiocak, H. Chung, E. McMillan, S. Wu, J. De Brabander, K. Komurov, J. E. Toombs, S. Wei, M. Peyton, N. Williams, A. F. Gazdar, B. A. Posner, R. A. Brekken, A. K. Sood, R. J. Deberardinis, M. G. Roth, J. D. Minna and M. A. White (2013). "Systematic identification of molecular subtype-selective vulnerabilities in non-small-cell lung cancer." Cell 155(3): 552-566.
Potts, M.B., Kim, H.S., Fisher, K.W., Hu, Y., Carrasco, Y., Bulut, G.B., Ou, Y.-H., Herrera-Herrera, M.L., Cubillos, F., Mendiratta, S., Xiao, G., Hofree, M., Ideker, T., Xie, Y., Huang, L.J.-S., Lewis, R.E., MacMillan, J.B., and White, M.A. (2013). Using Functional Signature Ontology (FUSION) to identify mechanisms of action for natural products. Sci. Signal., 6(297), ra90.
Ward S.E., Kim H.S., Komurov K. Mendiratta S., Tsai P.L, Schmolke M., Satterly N., Manicassamy B., Forst C.V., Roth M.G., García-Sastre A., Blazewska K.M., McKenna C.E., Fontoura B.M., White M.A., "Host Modulators of H1N1 Cytopathogenicity," PLoS One, 2012;7(8):e39284. Epub 2012 Aug 2.
Goldsmith E.J., Mendiratta S., Akella R., Dahlgren K., "Natural language query in the biochemistry and molecular biology domains based on cognition search™," Summit on Translat Bioinforma, 2009 Mar 1;2009:32-7.
Garcia-Rodriguez J., Mendiratta, S., White, M. A., Xie, X.-S., and De Brabander, J. K. 2015. Synthesis and structure-activity studies of the V-ATPase inhibitor saliphenylhalamide (SaliPhe) and simplified analogs. Bioorganic and Medical Chemistry Letters, 25:4393-4398.
Li, Y., Mendiratta, S., Ehrhardt, K., Kashyap, N., White, M. A., Bleris, L. 2015. Exploiting the CRSPR/Cas9 PAM constraint for single-nucleotide resolution interventions. Plos One, 11:e0144970.
Jean René Clemenceau - Research Assistant I
Education: B.S. - Informatics, 2013, Baylor University
Role: I am the administrator for the lab's databases and servers. I also develop and mantain the lab's different software tools. These include web user interfaces used to access and analyze the data produced and gathered by the lab and fellow contributors within our different projects. I strive to create user-friendly tools that can increase the efficiency of drug discovery out of massive amounts of data.
Principal Investigator
Michael A. White, Ph.D. – Professor, Cell Biology
Grant A. Dove Chair for Research in Oncology
The Sherry Wigley Crow Cancer Research Endowed Chair in Honor of Robert Lewis Kirby, M.D.
Education: University of Iowa (1986), Undergraduate; University of North Carolina at Chapel Hill (1992), Graduate
Research Interests: Cancer, molecular architecture of growth regulatory signal transduction cascades, oncogenes, signal transduction and tumor suppressors
Publications: 1992 – 2015


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A multiplicative decomposition of Herfindahl concentration measure
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Volume (Year): LIX (2001)
Issue (Month): 1-2 ()
Pages: 3-10
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- Shorrocks, A F, 1980. "The Class of Additively Decomposable Inequality Measures," Econometrica, Econometric Society, vol. 48(3), pages 613-625, April.
- Bourguignon, Francois, 1979. "Decomposable Income Inequality Measures," Econometrica, Econometric Society, vol. 47(4), pages 901-920, July.
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- Snapshots From the Meeting
These snapshots include new evidence that changes in the appearance of martian gullies from year to year are the result of carbon dioxide frost (aka dry ice) and that geological barriers delayed an earthquake by temporarily holding back injected wastewater from fracking.Permalink:


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Like in bug 331125 we need to bump version to 1.0.2 for the next security release from 1.8.0 branch (based on Gecko 22.214.171.124).
Created attachment 220956 [details] [diff] [review]
bump version number to 1.0.2
OK, here's the patch. If still check in before the freeze today nightnight, we can go without additional drivers' approval, else we need to request that as well.
Checking in mozilla/xpfe/bootstrap/module.ver;
/cvsroot/mozilla/xpfe/bootstrap/module.ver,v <-- module.ver
new revision: 22.214.171.124.2.3; previous revision: 188.8.131.52.2.2
Checking in mozilla/xpfe/bootstrap/version.txt;
/cvsroot/mozilla/xpfe/bootstrap/version.txt,v <-- version.txt
new revision: 188.8.131.52.2.3; previous revision: 22.214.171.124.2.2


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- Summary: Experience roller coaster speed and drops, multiple 3D texture-mapped tracks, and futuristic vehicles in this out-of-control hovercraft racing game. Pick up weapons to blow your opponents off the course, or pick up shields to defend the lead.
- Developer: Psygnosis
- Genre(s): Driving
- Cheats: On GameFAQs
- More Details and Credits »
Score distribution:
Positive: 0 out of
Mixed: 0 out of
Negative: 0 out of


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June 22nd, 2015
Episode 468 of 1214 episodes
Have you visited Oscar Wilde's grave in Paris or had a pint in the Sherlock Holmes pub in Charing Cross? If you have, you're not alone. Literary tourists of all ages and nationalities are visiting their favourite fictional places and authors haunts, right around the world.
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Double tap to screen on/off like LG G3
38 comments
When double tap for wake up will be available? I've download the prime version but unable to find the setting.
Mark Schmitz commented
I have LG G3 on Android 6.0 and I use Nova Prime. I use smart unlock directly in Android.
When I use double tap to screen with the option "screen off" Nova not only turns off the screen but locks it.
LG launcher only turns off the screen. Please fix Nova, so the screen only turns off and does not lock. Thanks!
data commented
I have Prime version. The option double tap for wake up will be welcome.
Here's another vote for adding the "double tap to wake" feature in Nova Prime.
My LG Volt phone has it and I'd love my Samsung Galaxy Tab 2 to be able to do that too.
allow administrator and use gesture. that should work fine!!
double tap screen of but not on please update on option
GO launcher has this implemented and is the only feature that might make me decide to choose GO over NOVA. C'mon guys implement it... using 3rd parties apps is not the solution
Simone commented
I would also like to see this implemented. Relying on third party apps gives a buggy experience overall, and Nova already has this on the status bar, so I imagine giving the possibility to bind it to another gesture wouldn't be too much work.
Thomas Novin commented
Using gesture > double tap with 3rd party app Screen Off is not a solution, because that app doesn't support SmartLock. So the screen will be locked, even though it should be kept unlocked by SmartLock.
So please fix so that double tap = screen off, not the notification bar.
Michael Canning commented
Anonymous commented · September 10, 2014 15:53 · Flag as inappropriate
with nova installed. you can double tap the notification bar.
this works Awesome for me on the LG G4
I love the Nova Prime
dns commented
Please integrate screen locking on double tap. When using external app, the lock sound is played twice. Super anoying thing.
Barksino commented
I have a LG G3 and only because of this function I switched to GO Launcher because GO launcher supports double tap gesture for screen lock/off. You should consider to implement this very useful function in the NOVA launcher.
Zeeshan commented
This is an excellent feature of LG Phones.
I highly recommed the addition of this feature to NOVA Launcher.
Petri commented
Yep workaround is that you install app like "Screen Off and Lock" then use double tap gesture to lauch it.
Also you can use double tap to launch Greenify shortcut that will hibernate apps and turn screen off.
Dean Milord commented
Install app screen off. Set as a gesture on the homescreen.
Aung Lay commented
i want to use
Sebastián commented
En la configuración de gestos de Nova Launcher debería tener una opción que sea: predeterminada del sistema, o bien la opción "No Action" debería dejar libre a la predeterminada del sistema.-
Sean commented
Try solo launcher. Using it now and allows double tap to turn off and on. Works perfectly.
I just added that as a gesture on the app settings.
Filip Rek commented
It's a kernel feature, no hardware bullshit.


text: Samsung Leaks ARM's Roadmap For Next Three YearsKat Hannaford4/22/10 5:30amFiled to: ProcessorsArm leaked roadmapArmarm AquilaArm taurusArm mercuryArm orionArm pegasusArm herculesArm venusArm draco30EditPromoteShare to KinjaToggle Conversation toolsGo to permalink Thanks to Samsung leaking a document, we now have details about ARM's roadmap for the next three years. It's not the best leak of the decade (or even the century), but helloooo 2013's Aquila, the 1.2GHz quad-core Cortex-A9. Listed in the leak is Taurus, the single-core 1GHz S5PV210 Cortex-A8 chip which will arrive later this year, Mercury, which is a 600MHz single-core Cortex-A5 which will be available either this year or next, Orion, an 800MHz Cortex-A9 which we'll see early next year, Pegasus which we'll see later in 2011 (a single-core 1GHz Cortex-A9), Hercules the 1GHz dual-core Cortex-A9 which will appear early 2012, and in 2012 - 2013 Venus, which is a 600MHz Cortex-A5 dual-core chip, and Draco, another dual-core but at 1.2GHz Cortex-A9 flavor. Advertisement Advertisement ARM's got to be feeling pretty peeved at Samsung for leaking their goods—but at least we know they've got the support of a major manufacturer for the next few years, with their chips looking set to replace Intel's in upcoming laptops and other products. [EeTimes via Notebook Italia via SlashGear] Reply30 repliesLeave a reply


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Wisconsin-Iowa report card
Jeff Potrykus reviews Wisconsin's 28-9 victory Saturday over Iowa:
Completing passes in the windy conditions couldn't have been easy. However, quarterback Joel Stave was all over the map early. To his credit, he settled in and made some important throws. His best was the 44-yard touchdown pass to Jacob Pedersen.
Stave looked to the right, where UW had three wide receivers, including Jared Abbrederis. That led both safeties to focus on that side of the formation. Given time by his line, Stave deftly stepped up into the pocket while looking right, then suddenly looked left to the backside and fired a dart to Pedersen for the score.
Pedersen, in case you haven't noticed, has become a consistent receiving threat.
Iowa crowded the line of scrimmage and stuffed UW's running game early. The linemen and tailbacks James White and Melvin Gordon didn't waiver, however, and that persistence paid off in the second half. White's patience on his 11-yard touchdown run was impressive.
My guess is that offensive line coach T.J. Woods didn't agree with the holding call on left tackle Tyler Marz, a penalty that wiped out a 17-yard touchdown run by Gordon.
No Chris Borland? No Tyler Dippel? No problem. Marcus Trotter struggled in the open field because of a lack of speed, but he filled holes and delivered blows in tight quarters. Iowa likes to run to the short side of the field, which plays into Trotter's strengths.
Safety Nate Hammon and Trotter helped blow up a fourth-and-1 play at the UW 35 in the third quarter with the Badgers leading, 7-6. Later, Trotter's pressure contributed to the interception by Pat Muldoon.
Muldoon's workload increased because of Dippel's absence, and he contributed the interception, a pass break-up, a quarterback hurry and solid play overall.
Cornerback Darius Hillary baited Iowa quarterback Jake Rudock into thinking tight end C.J. Fiedorowicz was coming open and then closed hard to make a critical interception.
This was the type of game defensive end Ethan Hemer enjoys. Hemer entered the day with two tackles and recorded three against the Hawkeyes.
UW generated consistent pressure against both Iowa quarterbacks, which led to seven hurries. That was a key factor.
If UW had more play-makers at wide receiver, Abbrederis might be in line to replace Kenzel Doe on punt or kickoff returns.
Doe generally displays sure hands on punts. However, he doesn't appear confident sprinting up to field short punts. That indecisiveness resulted in a muff that was recovered by Dezmen Southward at the UW 33 early in the third quarter.
Doe's decision to bring the ball out of the end zone on a kickoff return after the Hawkeyes' third field goal was a mistake. That cost UW 7 yards because Doe was tackled at the 18.
The ability of punter Drew Meyer to execute rugby kicks and Aussie-style kicks gives UW an effective weapon. His 48-yard punt, into the wind, that was downed at the Iowa 1 was huge.
The coverage units continue to excel.
The defensive assistants had their side of the ball ready for a physical, pro-style offense after a steady diet of spread attacks. This week the pendulum swings back to an up-tempo, spread attack with BYU visiting Madison. That will be a tough transition.
The use of freshman Corey Clement as the motion man on what appears to be a jet sweep is another nice wrinkle. Clement hasn't gotten the ball yet, but at some point he will.
Does anyone remember the last time UW allowed a huge kickoff return? Bill Busch is in charge of that unit, which has been sound for most of the season.


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Q: Is bruising easily a health concern?
A: A bruise forms when small blood vessels under the skin break, dumping some blood into the tissue that can be seen from the surface of the skin. Gary Chuang, director of the Dermatologic & Cosmetic Surgery Center at Tufts Medical Center, says that one of the main reasons people bruise more easily is because of age. As we get older, the skin loses collagen, as well as the ability to retain water. "These two building blocks of skin are basically like air bags that protect the blood vessels underneath," he says. Simple bumps and dings leave bruises because there's less of a cushion protecting their blood vessels.


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Description: Herold Newspaper building and surrounding commercial area at the southwest corner of Broadway and Mason Street. Pedestrains cross the street and horse-draw...
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The video is gone but the caption is oh so true!


text: Nathan Ironside Nathan Ironside & El Despertar Sydney "There is a stirring of worship in the earth, hearts alive + awake + responding now" Nathan Ironside is a lead worshiper, singer, & songwriter from Australia. He has been writing songs & leading worship in churches passionately since he was 15 years old. Nathan is now based in NW Indiana, USA, and with his wife Mary they are the Worship/Creative Pastors of Road to Life Church, Chesterton (One of the fastest growing church plants in the USA). Nathan's previous experience includes worship leading and music directing at Hillsong Church, Sydney, Australia. Nathan & Mary both served extensively, with Nathan also lecturing at Hillsong College and being involved in studio & production projects. As a producer Nathan has produced over 30 albums & written many songs for other artists, this history of worship and creativity led to the healthy beginnings of what is now "The Stirring" (Established by Nathan & Mary in 2011). "The Stirring" is the ministry heart behind the music. "Our purpose is to inspire authentic worship ... We were born to worship!" In 2012 Nathan led worship next to US worship group 'Jesus Culture' in Colombia, South America. In the last year 'The Stirring' has ministered to over 300,000 people in events throughout South America & the United States. "We want to inspire people everywhere to shake off in-difference, to reject apathy, to express their worship with passion, & with a lifestyle of surrender before the highest King" Says Nathan. The latest album "Light of Your Glory" is an epic and energetic worship journey that will inspire you, and serve as a wake up call to the sound of worship in your life. Available in English & Spanish the album features the songs 'Awaken my City', 'Born to Worship' and 'Power to Save' which has now become a project and a movement resourcing churches with stories of salvation on video: www.powertosave.me Nathan's first album 'Sound of a new day' features musicians from Hillsong Church, Australia, Henry Seeley of 'Planetshakers', & worship leaders from Colombia, South America and is also available in English & Spanish. To have Nathan Ironside & The Stirring ministry at your church, worship event, or for training workshops with worship teams, songwriters and musicians please contact: Email: email@example.com Twitter: @nathanironside Facebook: www.facebook.com/TheStirringinme Nathan Ironside's tracks Persigues Mi Corazón by Nathan Ironside published on 2016/09/06 17:19:42 +0000 Wildfire - Power to Save by Nathan Ironside published on 2016/09/06 16:56:38 +0000 Shout His Fame by Nathan Ironside published on 2016/09/06 16:55:53 +0000 Wonder of It All by Nathan Ironside published on 2016/09/06 16:49:37 +0000 Spirit & Truth by Nathan Ironside published on 2016/09/06 16:49:26 +0000 Pursuer of My Heart by Nathan Ironside published on 2016/09/06 16:48:06 +0000 Wildfire - Stir up the Flame by Nathan Ironside published on 2016/09/06 16:47:28 +0000 Renew in Me by Nathan Ironside published on 2016/09/06 16:46:56 +0000 Blood Cries Out by Nathan Ironside published on 2016/09/06 16:46:55 +0000 We Are Free by Nathan Ironside published on 2016/09/06 16:46:42 +0000