text:
Directional Valve, Solenoid, Float, 12 VDC
PARKER| Zoro #: G2386702| Mfr #: D1VW004CNKW
Zoro #: G2386702Mfr. Part #: D1VW004CNKW
$273.96 /ea
This item ships free. DetailsStandard ground shipping
Technical Specifications
|Zoro #: G2386702 Mfr #: D1VW004CNKW
|Seal Type: Nitrile O-Ring
|Number of Positions: 3
|Type: Solenoid Operated
|Adjustable PSI Range: -
|For Use With: -
|Number of Ways: 4
|Item: Hydraulic Directional Valve
|Max. Pressure (PSI): 5000
|Series: D1VW
|Hz: -
|Holding Amps: -
|Width (In.): 1.81
|Size: CETOP-03
|Length (In.): 9.2
|Inrush Amps: -
|Max. Tank Pressure (PSI): 3000
|Height (In.): 1.97
|Standards: ISO 4401, NFPA D09
|Coil Volts: 12 DC
|Spool Type: Float
|Country of Origin (subject to change): Unknown
Product Description
Hydraulic Directional Valve, Solenoid Operated, CETOP-03 Size, Number of Ways 4, Number of Positions 3, Float Spool Type, Coil Volts 12 DC, GPM @ 3000 PSI 18.5, Max Pressure 5000 PSI, Max Tank Pressure 3000 PSI, Nitrile O-Ring Seal Type, Manual Override, Length 9.2 In, Width 1.81 In, Height 1.97 In, ISO 4401, NFPA D09 Standards
Restrictions and Compliance
- *1 : California Proposition 65 : This product contains a chemical known to the State of California to cause birth defects or other reproductive harm.
- *2 : California Proposition 65 : This product contains a chemical known to the State of California to cause cancer.


text:
- Horaires d'ouverture: 24 Hours 7 Days
- Temps de transfert à l'aéroport: Drop your car off at the terminal
- En votre absence, vos clefs de voiture devront rester à la réception du parking.
Meteor meet and greet parking provides you with a hassle-free start to your journey.
Simply drive direct to the terminal forecourt where a uniformed driver will meet you, allowing you to walk straight to check in. Your vehicle will be parked in a secure Park Mark car park located within the airport boundary
Your vehicle will be returned to you back on the forecourt, allowing you to drive straight home. It's the only way to Airport Park!!
Meteor Meet and Greet is operated by our partners I Love Meet and Greet who have over 30 years experience in providing meet and greet services.
Important: there is an airport levy fee of £6.00 which will be applied on the summary page of your booking. Please note that this is non-refundable should you cancel the booking.
Pourquoi Réserver Cette Place de Parking?
- Ultimate convenience - Meet and Greet service at STN airport
- 24hr security with electric barrier, CCTV & Park Mark award
- Fully trained, insured and uniformed chauffeurs
- Meeting point in the forecourt at terminal building
- Airport levy fee applies
Information Handicapés
No transfers are needed, Stansted Meteor Meet and Greet will be an excellent alternative for disabled customers who would find it difficult to use transfer buses. Your car is collected from the terminal when you leave, and brought back to you at the terminal on return.
Informations complémentaires
Please take a copy of your confirmation email with you on your day of travel.
This service is operated by our partners I Love Meet and Greet, who have been providing a parking service at Stansted for several years. Rest assured you and your car will be looked after at all times.
Procédure à l'arrivée
Please call the number on your confirmation when you are 10 minutes from the airport. Proceed to the Express Set Down – Follow signs for Express Set Down which is located directly outside the terminal building up on the forecourt. Drive along to the area marked zone C located centrally on right hand side of the terminal road. If there are any changes to the location point you will be advised when you call.
If you experience difficulties with the main contact number please use the Emergency number to contact the drivers. Postcode for SatNav is: CM24 1QW. This service is facilitated by our partner I Love Meet and Greet
Procédure au retour
Please collect all your luggage and clear customs BEFORE calling the driver number to have your vehicle delivered. Make your way to the forecourt, just outside the terminal doors and wait in Zone C, by the flag poles.
Please remain on the same level as departures.
We are unable to wait for more than 5 minutes, so it is therefore essential you are ready to collect your vehicle, otherwise YOU will be liable for any excess fees.
You will be notified of any changes to the meet point when you call. Emergency Number is provided on your confirmation. Our service is facilitated by our partners I Love Meet and Greet.
Adresse GPS
Postcode for SatNav is: CM24 1QW
Stansted Airport is sited around 40 miles north-east of the city of London, close to Stevenage and Chelmsford. It is close to the M11, after exiting here, follow the signs along the A120 to the airport.

subset: commoncrawl


text: Six of us -- four adults and two small children -- ate here for dinner last month. The atmosphere was friendly and embracing -- the kitchen staff all spoke Italian -- and the pizza was very good highlighted by a very thin crust and tasty toppings. Opt for any wine as long as it's Italian, naturalemente!


text:
To complement the full Hasbro Transformers Titans Return gallery posted recently, I have done the same for the TakaraTomy Transformers Legends series, or at least the toys that best correspond to the Headmasters-themed Titans Return toys. The only released figure missing from the set is the E-Hobby exclusive Convobat, but it will arrive in due course and it stands apart from these in some respects. This gallery will be updated with alt modes and any new releases as and when I get them, so enjoy!
Friday, 13 January 2017
Sunday, 8 January 2017
Transformers Titans Return - Wave 1 to 3
In this post you'll find my gallery of every Hasbro Transformers Titans Return retail release from waves 1 through 3, including SDCC exclusives. I will add TakaraTomy Transformers Legends figures soon, but it's mainly a place for me to keep my full gallery of pictures taken and edited using the vignette effect for an experiment. It ended up being a long experiment! So here they are, starting at wave 1 and with the biggest size class in descending order:
Monday, 2 January 2017
MMC Reformatted R-18 Anubis
Mastermind Creations regularly pay homage to prominent comic book characters from the Transformers universe with the continuing excellence of their Reformatted sub-line. With Reformatted R-18 Anubis, they bring Death's Head to the 3rd party scene, and as a transforming figure no less. Anubis uses the same mould as Jaegertron (Lockdown) as well as the upcoming Cyclonus, so there are inevitable compromises. This Marvel-born "Freelance Peacekeeping Agent" seems to be something of an expensive exclusive, but there's no shortage of interest in him, yes?
Saturday, 10 December 2016
Ocular Max PS-05 Girder
So here is Ocular Max (AKA Mastermind Creations) Perfection Series 05 "Girder", otherwise known as a 3rd Party interpretation of Masterpiece Autobot Grapple. This mould has already been used by Ocular Max for their Not-Inferno "Backdraft" and since the release of PS-05 Girder we have had a show exclusive "Road Crane" version of Hauler. Forgive the lack of gorgeous packaging in this review, I had to leave it in the UK!
Wednesday, 26 October 2016
Ex-Factory Gladiator
What we have here is the Ex-Factory Gladiator, a 3rd Party Masterpiece Transformers-scaled representation of the Generation 1 Centurion Droids as seen in "The Key To Vector Sigma" episodes. These droids guard the Vector Sigma supercomputer, are supposed to have impervious armour and be highly-skilled fighters. Interestingly, they are not supposed to be armed, but Ex-Factory have equipped them with a handgun.
Monday, 19 September 2016
Fansproject WB008 Trianix Alpha
Fansproject, a 3rd party company who have been part of the scene since the beginning, have just released their interpretation of the 1980 Diaclone Dia-Battles figure. This WB008 from the Warbot series is called "Trianix Alpha", in reference to the fact that the original Dia-Battles - and this Trianix - split into three individual vehicles but combine to form the robot. It has been produced to scale with Classics/CHUG figures but it stands taller than the TakaraTomy Diaclone Dia-Battles V2 that saw release in the late spring. I was aware of this release and had a passing interest, but when I walked past it on display at Kapow Toys during TFNation, that passing interest became a fervent fascination.
Thursday, 15 September 2016
Corbot V Mugger
Corbot V, 3rd party makers of Classics scale Transformers accessories such as the Blizzard Axe, have done a full transforming figure. Using the 'Allicon' transforming alligators of Quintessa as a base mould, Corbot V have gotten a few uses out of the tooling, but the one that interests me the most is CV-002 "Mugger". This instantly recognisable creature did of course debut in Transformers: The Movie in 1986. Think Energon goodies, think Bah-Weep-Gra-Na-Weep-Nini-Bong, there's a great deal of Movie accuracy here.
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text:
- Error
--Publisher's Description--
-Title: download frets on fire songs mac
Languages: Multiple languages
Last week:
-Last updated:
03/07/2015 14:02:53
-OS support:
Windows (all)
-User rating:
[4.2 out of 5] (158 votes)
TOP Downloads download frets on fire songs mac:
03/07/2015 14:02:53
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3:00 PM - 6:00 PM Sandburg dress rehearsal
3:00 PM - 6:00 PM Sandburg dress rehearsal
7:00 PM Gym Night at NHS
7:00 PM Gym Night at NHS
PSSA / Keystone info
Click here to read a letter to parents and guardians containing important information about the 2017 PSSA and Keystone tests. Click here for a PSSA information sheet from the PA Department of Education.
The PSSA testing window is April 3 through May 5 this year, and the Keystone testing window is May 15 through May 26.
Get Board agendas, documents online
Starting in January, all future Neshaminy School Board meeting agendas and public documents will be available online at least a day before meetings and archived for future viewing and searching at our new BoardDocs site, found here. Both this link and the link to past agendas and meeting minutes can always be found under the 'Board of School Directors' menu drop-down on this home page.
K-1 registration open
Students entering kindergarten in the 2017-2018 school year can now be registered through the online Central Registration site, found here. First-grade students new to the district can also be registered at this time. New students in grades 2-12 can begin online registration on April 3, 2017.
Strategic Plan
A summary of the Neshaminy School District Strategic Plan covering the years 2017-2021 can be viewed here.
Substitute teachers wanted!Do you have a bachelors degree and love working with children? Would you enjoy sharing your knowledge and wisdom with the next generation? Neshaminy School district is looking for substitute teachers right here in our schools. We can even help you obtain state certification through the Bucks County Intermediate Unit 2-day Guest Teacher program. For more information, contact any of our school principals or call Human Resources at 215-809-6606.
District art gallery
Each month, one school will be featured in an art exhibition in the Board Room at the District Administration offices in Maple Point. In January, art from Tawanka Elementary School is on display. You can also view the art works in an online gallery here.
2017-2018 Proposed Preliminary Budget
The proposed preliminary budget approved at the January 24, 2017 School Board meeting has been posted for public review and can be viewed here. Please note that this budget is a work in progress and may be modified before a final version is drafted for public inspection and approval.


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Theresa: Thanks for sharing that link...that was really cool to look at!
Melody, IA (Z 5/4)
"The most beautiful thing we can experience is the mysterious."
--Albert Einstein
--- On Sat 06/12, Tchessie < firstname.lastname@example.com > wrote:
From: Tchessie [mailto: firstname.lastname@example.com]
To: firstname.lastname@example.com
Date: Sat, 12 Jun 2004 18:53:27 -0700
Subject: [CHAT] Strybing plant sale- by luck!
Hi all-

Well I took my test this morning. Not too bad- we'll see
how the score is
in a few weeks. I didn't make it over to the Oakland
farmer's marker, so I
don't know if DF made it or not (or how his
daughter is). But....My husband
wanted to go to the planetarium and
aquarium in Golden Gate park. So, on the
way into the park, trying to
find both of the above, we came across Strybing
garden and they were
having a PLANT SALE (big huge sign on their front
gate). So I said
STOP! We have to go in. So I now have more plants that I
don't know
where I am going to put them! I got a kiwi (female- I'll have
to
order a compatible male) that has lovely red stems and very green
leaves.
Does get edible fruit too! I got 2 more salvia varieties
(saliva patens-
has lovely large vivid blue fowers, and "jean's
purple passion"- has similar
sized intense purple flowers). My
husband picked out a collection of
alpines and dwark conifers to make
a trough garden. He also picked up a
handful of succulents- 'because
they are more interesting' than regular
plants. Finally, he fell in
love with an Adenium obesum (desert rose) which
amazed me as he was
more than happy to fork over $25 for it. Now it will be
my challenge
to keep the most expensive plant I've ever owned alive! The
walk
throught the arboretum was lovely also, of course.

Turns out that
the aquarium is closed and they are doing all kinds of
construction
on something- so you can' get to the planetarium. So... we
when to
the conservatory instead. I have wanted to visit since they
finally
finished reconstructing it last year and opened it to the
public again. It
is gorgeous. Each room has a different climate,
amazing specimen plants
(including a 100 year old philodendron),
orchids, umpteen potted tropicals,
a watergarden, cloud garden etc.
It's hard to imagine that some insane
businessman many years ago
bought the conservatory as a KIT- it was shipped
over in wooden
crates. The
poor guy died before it was built!

here's a link if you want to
see where we were
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Psalm 80International Children's Bible (ICB)
A Prayer to Bring Israel Back
For the director of music. To the tune of "Lilies of the Agreement." A song of Asaph.
80 Shepherd of Israel, listen to us.
3 God, take us back.
4 Lord God of heaven's armies,
7 God of heaven's armies, take us back.
8 You brought us out of Egypt as if we were a vine.
12 So why did you pull down our walls?
14 God of heaven's armies, come back.
19 Lord God of heaven's armies, take us back.
International Children's Bible (ICB)
The Holy Bible, International Children's Bible® Copyright© 1986, 1988, 1999, 2015 by Tommy Nelson™, a division of Thomas Nelson. Used by permission.
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HUNTINGTON, W.Va. | Cody Green threw his only touchdown pass, a 4-yarder to Jordan James for the go-ahead score midway through the fourth quarter, and Tulsa stopped Marshall on downs twice in the fourth quarter to seal a 45-38 win.
The Golden Hurricane's quarterback connected with Thomas Roberson on the two-point conversion to follow up his touchdown, putting Tulsa (5-1, 3-0 Conference USA) up by seven with 8:25 remaining.
Then the Tulsa defense took over. Lowell Rose broke up a Rakeem Cato pass on Tulsa's 16-yard line on fourth-and-5 to stall a Thundering Herd (2-4, 1-1) drive with 3:32 left. Less than two minutes later, Tulsa's Marco Nelson broke up another pass by Cato on fourth-and-7 at the Golden Hurricane's 17 to stall Marshall's final possession and seal the win.
Alex Singleton rushed for three touchdowns on 94 yards for Tulsa. Cato had three TDs and 391 yards passing for Marshall.
Alabama Birmingham 52, SE Louisiana 3
BIRMINGHAM, Ala. | In his second collegiate start, Austin Brown bolstered Alabama-Birmingham to a 28-point halftime lead as the Blazers earned their first win of the season — a trouncing of Southeastern Louisiana.
A week after amassing 337 yards and three scores through the air in a loss to Tulsa, Brown helped beat the Lions (2-4) by completing 16 of 22 passes for 266 yards and a touchdown, all before the half.
UAB (1-4) went on scoring drives of 68, 78, 59 and 56 yards in the first half, and also scored on Marvin Burdette's 36-yard interception return for a touchdown.
Boise State 40, Southern Mississippi 14
HATTIESBURG, Miss. | Joe Southwick threw for three touchdowns and Boise State took advantage of five turnovers to breeze past Southern Mississippi.
The Broncos (4-1) won their fourth straight by intercepting Golden Eagles quarterback Ricky Lloyd twice and recovering three of four fumbles by Southern Miss, which is 0-5 for the first time since 1976.
Louisiana-Lafayette 41, Tulane 13
LAFAYETTE, La. | Alonzo Harris ran for 123 yards and a touchdown on 23 carries and Louisiana-Lafayette piled up 294 rushing yards in a victory over Tulane.
Terrance Broadway threw for two touchdowns and ran for one for the Ragin' Cajuns (4-1), who won their eighth consecutive home game.
The Green Wave (0-5) lost their 15th straight game, and are 0-5 for the first time since starting 0-9 in 1991.
Broadway, who split time with Blaine Gautier before Gautier suffered a broken throwing hand last week, found Javone Lawson with a 23-yard touchdown pass to make it 10-0 in the second quarter.
C-USA Roundup: Tulsa Wins to Stay Perfect in C-USA
HUNTINGTON, W.Va. | Cody Green threw his only touchdown pass, a 4-yarder to Jordan James for the go-ahead score midway through the fourth quarter, and Tulsa stopped Marshall on downs twice in the fourth quarter to seal a 45-38 win.


text:
Dacheng is a full-service, integrated firm with a team of outstanding experts in the field of real estate.
Dacheng has considerable experience in the provision of the full range of legal services to all key stakeholders in major real-estate projects (including government agencies, developers, construction companies, lenders, investment banks, real-estate trust funds, property owners in owner-occupied construction projects and foreign/domestic investors) and an experienced team of professional real-estate lawyers.
More importantly, Dacheng has the ability to quickly put together a cross-disciplinary team of lawyers for the provision of timely, accurate, comprehensive legal services.
For more information on real estate and construction click here.
This material has been sourced from the Dacheng website.


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Reviews for San Giorgio VillasAddress: Fira, Santorini, Greece
Rooms from: US$ 39.22
Ratings Explained
(Hostelworld.com and Affiliate sites)
The following reviews were submitted by customers who booked through our sister site, Hostelworld.com, in the last 12 months.
The ratings in the rating box are based on all-time feedback for the property and are the opinions of the customers who submitted them; they do not express the opinions of Hostelworld.com or our affiliate sites.
Overall Rating (13 Ratings)
Customer Reviews for San Giorgio Villas
nehapurohit8129346, from India ~ 21st Apr 2016
rinkusahay705, from India ~ 22nd Apr 2016
aaronkooris4970, from USA ~ 22nd Apr 2016
mflah4211, from USA ~ 28th Mar 2016
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jungheum9253439, from South Korea ~ 26th Mar 2016
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text:
Citi Open
The Citi Open is the longest running ATP tour event in the United States and is located at the William H.G. FitzGerald Tennis Center in Washington, DC. WTEF is the proud beneficiary of the Citi Open, an event that showcases the best in professional tennis, while at the same time giving back to tennis and the community. To show our appreciation to sponsors and donors of WTEF Tennis Ball by giving reserved seating, air conditioned suites, and box seats to the Citi Open. WTEF students participate in activities during the tournament on and off court.
WTEF Hall of Fame
Each year the WTEF Hall of Fame, Presented by Citi honors individuals who have given selflessly to support and grow the organization throughout its history. Inductees include:
The Honorable William H.G. FitzGerald
The Honorable Norman Dicks
Zina Garrison
Charlie Brotman
Dwight Mosley
Albert "Allie" Ritzenberg
Hon. John Breaux
DD Eisenberg
Willis Thomas, Jr.
Donald Dell
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Hon. Henry Kennedy
Peter B. Work


text:
Every man wants to know, how to make your dick bigger. Of course men always want more size. It doesn't matter that woman don't care about the size of your penis, you care. One search on the internet will give you hundreds of thousands of search results. You can find everything from penis pumps to pills to make your girth and length better. Medical research suggests that none of these methods work but it doesn't stop men from trying them out at a steep cost. On average, if a male is looking to enlarge his penis size he is willing to spend over $1,000 a year in doing so. This is money that is spend on supplements and tools to aid in his journey.
The only well researched and documented to record any sort of size change is herbal supplements. With all supplements though, it's better to buy them locally and through a vendor that you trust instead of a website that has no rules or regulations through the FDA. Ginseng is easy to come by at your local grocery store, the healthy effects of this herb have been known to increase your growth. It's easy to infuse in a nice hot tea with a little ginkgo to boost your metabolism also. If you don't like the flavor, try crushing some watermelon in it! Yes, watermelon. The properties in watermelon have shown progress as a super food for men, increasing the size and longevity of an erection.
Your lifestyle also affects the size of your penis. If you truly want to make your penis larger, you need to change your lifestyle. Weight Loss is one key element. When your body is able to grow and enhances itself, all parts will grow. However, if your body is too busy fighting back excessive weight and health problems. It will not be able to properly get the functions needed to grow. Another added bonus is though weight loss, you may not grow but if your body is fit and trim, it will make your penis appear larger than if you were overweight.
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Fedena Pro Version Needed
This project received 4 bids from talented freelancers with an average bid price of ₹27930 INR.Get free quotes for a project like this
Project Budget₹12500 - ₹37500 INR
Total Bids4
Project Description
i am using fedenaopensource since 2 years... But it does not having the plugins link Transport,Hostel, Blog and more plugins..
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i need all modules which is in pro version. if you have the this plugins which is developed no problem you can give to me..
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here is the deom for Basic version
[url removed, login to view]
Ruby n rail developer only bid on this project.
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Creative Signs
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My father has gifted me his self acquired residential property under a registered gift deed. The Khata of the property now stands in my name and I am paying property tax regularly in respect of this property. I have a married sister. My question to you is whether my sister can claim a share in this property after the death of my father?
Since the house property which has been gifted to you by your father under a registered gift deed was his self acquired property over which he had absolute right, title and interest which can be alienated at his sweet will, and the khatha of the property now stands in your name, the gift is absolute and irreversible. The question of bringing the ancestral property right by your sister doesn't arise in this case since the property was purchased by your father from out his own earning and hence he had authority to dispose of this property as he like. Therefore, your married sister shall have no right whatsoever either now or at a later date in respect of this property.


text:
The Cambridge Companion to Tennessee Williams
Edited by Matthew C. Roudane
Format: Paperback
Normal Price: $74.95
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Shipping: $7.95 per order
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Plus...earn $3.37 in Boomerang Bucks
Availability: Available to Backorder, No Due Date for Supply
Cambridge Companion to Tennessee Williams by Matthew C. Roudane
Book DescriptionThis is a collection of thirteen original essays from a team of leading scholars in the field. In this wide-ranging volume, the contributors cover a healthy sampling of Williams's works, from the early apprenticeship years in the 1930s through to his last play before his death in 1983, Something Cloudy, Something Clear. In addition to essays on such major plays as The Glass Menagerie, A Streetcar Named Desire, and Cat on a Hot Tin Roof, among others, the contributors also consider selected minor plays, short stories, poems, and biographical concerns. The Companion also features a chapter on selected key productions as well as a bibliographic essay surveying the major critical statements on Williams.
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Book DetailsISBN: 9780521498838
(228mm x 152mm x 17mm)
Pages: 304
Imprint: Cambridge University Press
Publisher: Cambridge University Press
Publish Date: 11-Dec-1997
Country of Publication: United Kingdom
Other Editions...
Books By Author Matthew C. Roudane
Methuen Drama Guide to Contemporary American Playwrights, Paperback (December 2013)
This is an authoritative single-volume guide to the work of twenty-five American playwrights from the 1960s to the present written by a team of twenty-five eminent scholars from the USA, Canada, Britain, Germany and Ireland. It is the perfect companion for students of American literature and drama.
Cambridge Companion to Sam Shepard, Hardback (May 2002)
A fascinating exploration of one of the most influential American playwrights of the contemporary stage.
Cambridge Companion to Tennessee Williams, Hardback (December 1997)» View all books by Matthew C. Roudane
This collection of thirteen original essays covers Williams's work from the early apprenticeship years in the 1930s to his last play before his death in 1983.
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text:
this dream was full of calumets
© Copyright 2017 moonphish. All rights reserved.
Status: Finished
Genre: Poetry
ahhhh, from corncob to hookah. that was a trip, a travel, a dream, a rondo. through pipes and tunnels - plumbing the depths - and with tents, yet. the tents--what a fantasmagorical add in...
Wonderful imagery
Poem / Poetry
Poem / Poetry
Poem / Poetry
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text:
I knew he would still be mad at me. I ran into my ex , Gage, who used to be Danny's best friend in college, on my lunch break and we had lunch together. We talked about work, family, and the past. He told me he missed me and asked when Danny and I would break up so he could have me again. Then he went on to tell me how he envied Danny because Dan got my cherry. I told him how much I love Danny and that no one would make me as happy as Danny does.
Danny was always jealous of Gage, when Gage had me. Gage cheated on me, with another girl, in my bed. My heart was broken. He caused most of my insecurities. I was a mess. And when the opportunity arose, Danny swept in. Danny hates Gage for what he did to me.
I wasn't going to tell Danny about any of the lunch. However, when he called, he asked what I did for lunch, and I didn't want to lie to him. He heard everything and didn't say anything. He became passive and quiet. I knew he was jealous and mad at Gage, but he could only take it out on me.
When I got home he was playing his football, video games. I greeted him and he said nothing. I asked how his day was, he just mumbled. I asked what he wanted for dinner, more mumbling. The silent treatment. I removed off my heals and took them upstairs to put them away and change.
I put my shoes in their place and noticed the box of sex toys wasn't in its place. I opened it and saw that he had bought a new toy. He bought a plug. It was pretty big. We hadn't even had anal sex yet. I knew he has wanted to try, but I've been too scared. Now that I look at the toy and picture it in my ass, completely filling me, only being able to see the round end of it between my ass cheeks. I get really horny and wet.
I decide that I don't only want to cheer up Danny, but I really need to have sex with him. I take off my cloths and put on one of Dan's button up shirts, not wearing my bra, but still wearing my black, boy short, underwear. I go back downstairs. He doesn't look up at me. He just continues to play his video game.
I ask him again what he wants for dinner and he snappily replies, "I don't care."
Making and executive decision, that I don't want to cook, I call for a pizza. It will be here within the hour.
I sit down next to him on the couch. Placing my hand on his thigh, I kiss my way up his neck to his ear. He makes me so hot. We can both see a difference in our bodies since we got a gym membership. Iv just lost a few pounds, while I kept my curves and huge assets and he got more beefy and muscular.
He continues playing his game. I start rubbing his thigh and let my hand run over his package. I rub his dick through his sweats. He slides away from me on the couch. I know I'm wearing down on him. So I lean over and whisper in his ear that I want him to take me in the ass tonight.
He looks at me for the first time. "You're playing with me. You do not."
He returned to his game. I back up to the arm of the couch and start unbuttoning his shirt that is on me. I only unbutton the top four and move the shirt to the sides of me, exposing my breasts. He is still playing his game, but I can tell he isn't paying as close attention, due to the booing crowd in the TV.
I grab by tits and rub them all over, caressing them. I'm hoping he will take over for me. I rub my nipples and moan in pleasure. He is really having a hard time ignoring me. I can see his bulge growing with every soft moan. I really damaged his pride for him to be so mad. I remove my panties and kick them so they land, perfectly, on the remote control he's holding. I place my hand on my mound and start rubbing, really overdoing the fake moans.
He watches my hand rub my pussy lips up and down, rubbing the hot juices all over. I keep my eyes glued to his, while he watches my hand, and I insert one finger into my hole. He licks his lips. "Why are you doing this to me?" he asks.
"I want you so bad honey. Please take me."
He looks into my eyes, and nods his head around when childishly replies, " Why? When you can have Gage."
I stop moving my hand, "You were the first person in my pussy, I don't want anyone else to be the first one in my ass. You're the one that bought that new toy, weren't you? I want to use it with you. Please make hot love to me."
I slide closer to him and kiss his lips, pressing my breasts to him. My hand goes back to his thigh and moves up to his hard penis. He kisses me until I'm on my back and leans up to help me remove his T-shirt. He goes back to my lips. My hands are placed on his head while he uses his for support, as to not crush me with his large frame.
His left leg is between both of mine. With how horny I am, I start grinding my pussy against his leg, soaking his grey sweats. He can feel the wet heat on his thigh and his bulge grows even more. He places his hand on my left breast and grabs tight, almost so that it is painful, but not yet. He rubs it and flicks his finger over my nipple, making it even harder. "You look so sexy in my shirts, but you look sexier with out anything on."
I start unbuttoning his pants and he unbuttons the rest of my shirt. We are both desperate for each other now. He throws the shirt across the room, while he stands up and kicks his pants off. I sit up on the couch, smile, and reply, "You look sexy when your pride hurts."
"I'll show you what's going to hurt." He takes off his underwear while he's standing and his cock springs out. He is so erect and I can hardly wait any longer to contain his cock in my pussy and ass. He returns to me on the couch and kisses me hard, and passionate, pushing his tongue past my lips. He starts his assault on my right nipple, flicking, pinching, and tweaking it.
His lips move down my face, down my neck, down my chest, and to my left nipple. He grabs hold of my right tit while the sucks on my nipple. He flicks his tongue across it and sucks it, continuing a pattern of that before he moves on to the right breast.
My already wet pussy becomes uncomfortable with desire. His every touch makes me want him more, many times over. He looks up at me and kisses my lips. He takes my curves in his hands and I wrap my legs around his hips. He barely picks me up, turns around, and lies on the couch so I'm on top of him.
I position myself just right, on top of him and rub my pussy up and down the length of his shaft. His face is placed with agony. "Fuck, baby. Come on. I'm not getting any harder."
I reach down and grab his penis, position it to my hole, and in one hard, quick movement, swoosh myself all the way down on his cock. I gasp, he moans in surprise and pleasure. My twat moves up and down on his penis. His hands extend to my tits and he grabs them firmly, rubbing my nipples every so often. I'm in pure ecstasy.
I speed up, slapping my self against him and he places his hands on my love handles, helping me come down harder. My hands are on his chest, my thumbs rubbing over his nipples. "Baby, I'm going to cum if you don't hurry."
I stop all movement. "You cant cum."
"What? Why?"
"Because I still want you in my ass."
"You were serious? I thought you were just saying that to make me hard."
"Babe, I saw the toy, it made me hot. I want to try it."
His eyes lit up and he started moving my hips to make me continue. Getting the hint, I resumed my motions and went right back to doing it just as hard and fast. He places a hand on my mound and rubbed my clit with one finger, I exploded immediately, into an orgasm. Much to my surprise, when I calmed down, he pumped into me five times, hard, and shot his hot seed into my wet pussy.
Shocked, I lightly slapped his chest. "What the hell!"
He smiled. "You made me even more hot when you told me that. I couldn't hold it in."
I slid off of him, his seed flowing out from my pussy, got up, and went and got his shirt. I put it on but didn't button it, just wrapped it around me to cover up. "I told you I wanted to take you in my ass. I want to have more fucking sex. I have a lot more in me!"
"So do I! I'm not done. Fuck baby, I can get it right back up for that." He chuckled a little bit. When I asked what was so funny, he replied, "I can't believe your throwing a fit because you want more sex. I never thought that day would come."
The truth is, I want sex a lot more than I let him know. And even though he came inside my pussy and I was mad, I loved the rush of not knowing if he just shot the seed that might impregnate me. The rush makes me feel good. And I love his semen in my pussy. Its just as hard for me when I hold out as it is for him.
Just then, the doorbell rang. I buttoned a couple buttons and grabbed the cash from the table. Danny put his underwear back on, went into the kitchen so the pizza guy couldn't see him, and he retrieved a couple plates and a beer while I answered the door, half naked, with no panties, and hungry.
The young, dangly limbed teenager let his eyes roam my body for a second. His eyes stopped at my covered breast and saw my hard nipples through my shirt. I could feel Danny's hot cum, mixed with my juices, racing its way down my thigh, so I tried to hurry up the process by holding out the money to him, before he noticed. He got the hint and gave me our pizza. He stole another quick look at my body before I, kind of roodly, shut the door on him.
I set the pizza down on the dinning room table and walked into the kitchen. Danny took my and in his and checked me out. I felt the cum running down my thigh. Dan grabbed my waste and lifted me onto the kitchen counter. He spread my legs open and took a paper towel. Then he wiped my pussy, and wiped down my thigh, cleaning me up. He threw the soiled paper away. He kissed me on the lips and helped off the counter.
We sat down at the table and ate some pizza. He scarfed his down. I didn't eat much, even though I was hungry. My appetite left me when I started thinking about taking someone in my ass. I mean, Danny isn't just "someone". He is Danny.
I knew it was going to hurt. I hadn't slept with anyone before Dan, but I've seen other penises. Gage's, other boyfriends, and I have seen porn. Danny was pretty big. Nine inches, and really thick. Larger than any dildos I have had. Perfectly stretches my pussy. But my ass is tight. And I don't know if I want it stretched. It probably won't feel good at all. Maybe a little. All I know with my ass is that its felt good when Dan has stuck a finger in there while we had sex. A finger, as in one finger. A finger is way smaller than his dick.
He gets done eating and looks puzzled. He notices that I drifted away in thought. He takes our dirty plates and loads them into the dishwasher. I close up the pizza box and put the left over pizza in the fridge.
I pick up all of the cloths in the living room and put them in the laundry room. Danny waits around for me in the living room, waiting for me to talk. I walk past him and go upstairs, into our bedroom and into the bathroom. I go pee and brush my teeth. When I return into the bedroom, Danny is sitting on the edge of the bed, waiting to see what I do. He is wondering if I still want to do it.
He asked me what I was thinking about downstairs and I told him I'm nervous. He assured me that he doesn't want to do anything that I'm uncomfortable with and he won't be mad if I changed my mind. I straddled his lap, wrapped my arms around his neck and gave him a great, long kiss, forcing my tongue through his lips. He wrapped his arms around me, holding me up by my butt.
Our bodies were molded for each other like two puzzle pieces. After three years together, he still gives me butterflies when he kisses me. No one can give me this pleasure like he does.
My hips start to wiggle up and down over his limp package. I have a new mission, to arouse his dick again. As I circle my hips on/hump him, with his boxers on, my lips never leave his. His grip on my ass gets stronger. I break away from him and kneel on the floor. While I remove his underwear, to see his cock, yet again, I look him in the eyes. He is smiling and looking at me with so much joy in his eyes, its cute.
His underwear is thrown out of the way and I unbutton the shirt so he can see by breast. I inch my way between his spread legs. I take a hold of his half limp dick and lick the tip of it, tasting a little bit of my juice still on it. His penis becomes a little harder with just the first lick. I look up at him, wrap my lips around his shaft, and slide him into my mouth. I tease him by taking him, half hard, out of my mouth, "I want you to be the first to fuck me in my tight, virgin ass."
I slide his dick all the way in and out of my mouth again, lick all around the head, and talk dirty again, "When you've fucked my ass, I don't want you to cum in it, I want you to wait. I want you to put your new toy in it, really stretch my ass hole." Slide him in and out of my mouth again, "Then I want you to eat out my pussy and finger it, with the toy in my ass, until I cum on your fingers." Slide in and out again. He is very hard at this point, so I do it one more time, "And when I'm done Cuming, I want you to stick your dick wherever you want and fuck that hole until you shoot your hot seed in it."
"Fuck baby. I love it when you talk dirty."
"Mission accomplished." I winked at him and stood off the ground. I leaned down to kiss his lips and then crawled on the bed, up to the head of it. His eyes never left my body. I sat down, removed the shirt, and tossed it to the floor.
He turned around and crawled up the bed to me. He lay down, placing his head on the pillow, I followed suit. He removed my long hair from my face, gazing into my eyes. I moved my knee up between his legs, he was still hard. He kissed my lips lightly. "I want you to be comfortable. If you want to go through with this, it will hurt the first time, but I will make it enjoyable for you. You have to trust me. Do you?"
"Of course I do. I want to do it." He just made me fall more in love with him. The more I love him, the more I want to do things that will please and reward him.
He kissed me again and sat up. I followed. "Get on your hands and knees." I did so and he got behind me. He reached over to the nightstand to retrieve the lube. He squirted some on his hand and onto my ass. He rubbed it all over my ass hole, stuck a finger inside, and down over my pussy. He rubbed my clit a little bit and then he stroked his cock.
With much anticipation, I waited. He placed his cock at the virgin opening. He slowly, eagerly started pushing it in my ass. He pushed so slow and stretched my ass until I felt the head of his cock popped into my ass. He let out a breath containing pleasure. He slowly pushed his cock inside my ass. Inch by inch. I buried my face into a pillow. The pain was so much, and it was so uncomfortable. "Its all the way in babe. You did so well. You were so hot." He started inching his way out of my ass and that didn't hurt as bad. It almost felt good.
Right before the head came out, he slid his shaft back into me. He's groaning and moaning this whole time. "Fuck. Your ass is so tight Elli. It feels so good wrapped around my cock." I couldn't say anything because I wasn't sure about this yet. He kept sliding in and out of my ass slowly, and the more he did it, the better it felt.
I started moaning the faster he went, but he never went too fast. Just fast enough. He fucked my ass so good. He reached around and started rubbing my clit while he pumped in and out of my ass. The Pleasure was so good. I couldn't help but get louder with every hump. He rubbed my clit faster and his pumping picked up its pace. My head felt light and my body tightened up. Every part of me had goose bumps.
I let out a loud yell, and shook with a huge orgasm. Danny slid his cock out of my ass hole. "I almost came in your ass. That felt so good."
I was panting hard, "Fuck Dan. There are no words for that."
He got off of the bed and returned with something pointy and cold on my ass hole. He had but lube on it and pushed the plug in with one swift "plop". I let out a yell, partly in pain and partly in surprise. He helped me lean up so I was on my knees and my back against his chest.
It felt funny to have that in my ass. But good at the same time. Danny kissed my neck, down to my shoulder. He helped me turn partially around and then gently pushed me onto my but. I felt the plug wiggle around and my senses were heightened in my ass. He pulled my legs down so I was lying on my back. He got down, his face right up to my pussy, and licked it all the way up the slit.
He zeroed in on my sore clit and attacked it with licking, sucking and biting. He entered two fingers into my pussy and finger fucked me. He finger fucked me fast and gentle. Moans and sounds of pleasure escaped my lips. He sucked and flicked my pussy hard. He took his other hand and started twisting the plug in my ass. He began to remove it from my ass, and then pushed it back it. He was fucking my ass with the large plug. After a few seconds of this steady rhythm, my body let out another orgasm. My head was spinning and I felt like I was out of my body for a short time.
Danny grabbed my ankles, and held them together, holding my hips off the bed. He reached down and I felt him remove the plug. He set my legs down. "My turn. I want to fuck your pretty, mouth. I want you to moan all over my cock as I pump in and out of your mouth. I want you to taste all your juices on my cock."
I scooted down the bed until my face was right under him. He straddled over my chest and placed is cock to my lips. I took his erect penis into my mouth and swirled my tongue around the head of it. He pumped his cock in and out of my mouth while I sucked. "I love your lips around my cock." I moaned on his cock, sending vibrations all over it and letting him know I loved it.
He slid all the way out of my mouth, "I love pleasuring you with all of my holes." He instantly pushed his cock back into my mouth and to the back of my throat. He did that a couple more times. "I want to cum all over your titties. Suck me hard until I'm ready to cum. I am so close." He humped my head faster and I sucked harder.
He urgently popped out of my mouth and started pumping his shaft with his hand. He moved down my body, getting ready to cum. I leaned up on my elbows. "Cum all over my huge titties Danny. They need your hot cum all over them. All over my soft tits. I need it. Your so fuckin sexy Danny. Cum all over me."
My words sent his cum shooting onto my tits. He aimed for one nipple and then the other. With each squirt, his cum flowed onto my triple D breasts. He groaned with pleasure as his cum left his cock. He rubbed to semen all over my tits with his cock. All over my nipples and soft surface.
Danny climbed off of me as I scooped some of his seed up with my two fingers and sucked it off of them. When I sucked them all clean, he kissed me hard on the lips. "Thank you baby. Your so sexy."
He took my hands and guided me to the bathroom. He started the shower. He joined me and washed me. He made sure I was very clean. When we were finished, I put on a different shirt of his, a big T-shirt, and a new pair of blue boy shorts. He put on a new pair of briefs. We climbed in bed and snuggled close to each other. "Danny, I love it when you fuck all my holes. I love you and your big cock." I fell asleep with his hand tightly griped on my tit and his tiered cock pressed up against my butt.


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Bienvenu is TOPS state queen
Juanita Bienvenu of Patterson was crowned Louisiana State Queen during the Take Off Pounds Sensibly State Recognition Day Saturday at the Holiday Inn in Lafayette.
"We are very proud of her," said Berwick TOPS Chapter 0393 Leader Jodi Jett. "She has set an excellent example for our club members."
Nine members of the local chapter attended the three-day gathering held Thursday through Saturday.
Berwick chapter members also attending were co-leader Connie Thomas, treasurer Carole Hidalgo, secretary Dianne Baillargeon, weight recorder Tammy Clements, assistant weight recorder Lee Hebert, Julie McCarty and Jacquline Langston.
Bienvenu lost 129.75 pounds to reach her goal weight earning her the state title. She was also chapter queen. In Division 2, she took second place for her weight loss during 2012 while first place went to Chris Liner who lost 95 pounds last year.
In Bienvenu's personal success story for Recognition Day, she related the incident that propelled her to begin her weight-loss journey.
She wrote, "In May of 2010, I fell and broke my shoulder. All 274.75 pounds of me had to be 'picked up' by the thinnest Acadian Ambulance driver. A former student had to try to put a sling on me. Everybody had a harder job to do because of my weight."
The Patterson High School teacher learned that she liked the movement that therapy was giving her and wanted to move more.
"My friend Julie told me she had joined TOPS and it was working for her," Bienvenu said. "I was so needy! I didn't get out of the car the first night until I knew she was on her way."
As her weight shrunk, her confidence grew.
"What a journey this wonderful path to good health has been. I went from being totally dependent on others during my recoup time to a half marathon in 18 months," she proclaimed. "My doctors are actually proud of me; they tell me that I did it the right way!"
While fast food is no longer an option, she admits that the journey was aided by her husband, Luke. "By the way, my husband is the cook in the family; so literally, I could not have done this without him!"
She has been an inspiration not only to her fellow TOPS members, but to the faculty and students at Patterson High.
"A former student called me an athlete and that comment still brings tears to my eyes," she said.
Berwick's TOPS chapter meets Wednesdays at the Berwick Civic Complex. Weigh-in begins at 5:30 p.m. with the meeting at 6 p.m.
New members are always welcomed to the non-profit weight-loss meeting.
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Win A Trip For You & Dad To See Nickelback In Las Vegas!! [Video]
Give Back to Dad With Nickelback!!
Give Back to Dad With Nickelback!!
You wanna win the Soundtrack to the Hunger Games? Then just tell us who your favorite character is!
Join me tonight at the new Club 101 for a chance to win Wicked tickets.
Win Tickets to Wicked – The Musical!
Like Seize the Deal on Facebook and enter for a chance to win $1,000!
A Spirit of Michael - A Live Tribute Concert!
It's beginning to look a lot like Christmas!
Today after lunch I will call out the first name for the Great Purse Giveaway!
Win Rihanna's Latest CD!
LAST DAY to sign up for The 4 Thousand Dollar Holiday Showcase!
Join me this afternoon at GECU at 12400 Montwood & Joe Battle.
Today is the the last day to try and win tickets!
The New Mel Brooks Musical - Young Frankenstein will head to the Plaza Theatre this weekend...


text:
2011 Indians 40-man review: Who do they remove?
Trevor Crowe and Luis Valbuena may not
survive on the 40-man roster. (Photo: AP)
This is a key date in the offseason as teams set their 40-man rosters for the upcoming season by making decisions on which players to keep, which players to remove, and which young players to add in order to protect them from the Rule 5 Draft in December. The Indians already made two decisions on Tuesday when they outrighted outfielder Jerad Head and right-handed pitcher Mitch Talbot off the 40-man roster.
Most of the additions to the 40-man roster are who organizations view as their best young talent in the minors that is up for roster protection from the Rule 5 Draft. The rest of the additions come from signings through free agency with a few waiver claims or trades potentially sprinkled in. Teams conduct several meetings from the final month of the season until the roster deadline date as they work to whittle down the roster and finalize it before the deadline. Many decisions on who to remove and who to add from the roster are obvious, but other decisions are not so cut and dry.
Whether obvious or not, teams will wait until right around the deadline date to officially make roster additions from the minors in order to let things play out. Teams rarely make roster decisions on who to add well in advance of the deadline since there is no rush to do so and it could be a decision that results in disaster. What if the player being rostered is playing winter ball then goes out the next day and gets seriously hurt? This is a situation the team wants to avoid, and is why most of these decisions typically always go down to the last minute.
Occasionally, a team will open up a roster spot by trading a player already on the 40-man roster in exchange for a non-roster player that is not required to be protected. Even more rare are trades at this time of the year involving Rule 5 eligible players that teams may not have room on their roster to protect. This is mostly because other teams are in the same boat, and also because teams have little interest to acquire a player that if they are even interested in they can just go out and try to pick them up in the Rule 5 Draft for little cost.
When it comes to filling out the 40-man roster at this time of the year, it all comes down to a combination of need and talent. For a young team like the Indians that expects to contend next season and already has so many young players on the roster there is not as much focus on adding more youth to the roster this offseason as in previous years.
For the Indians most of the needed additions to the roster from their farm system this offseason happened over the course of this past season when they rostered such players as third baseman Lonnie Chisenhall, second baseman Jason Kipnis, right-handed reliever Zach Putnam and others. While there are still maybe two or three players from the farm system they will add to the roster, the additions the Indians make this offseason will likely mostly be Major League players via free agency or trade.
With all this in mind, let's take a look at what decisions the Indians may make in creating room on the 40-man roster prior to the November 18th roster deadline. In the next few weeks I will post a follow up to this piece and take an in depth look at what players from their farm system the Indians will consider adding to the 40-man roster.
Roster Breakdown
Currently the Indians have 42 players on the 40-man roster, four of which are on the 60-day disabled list. There is no disabled list in the offseason, so by the November 18th roster deadline the Indians will need to put all players on the 60-day disabled list back onto the active 40-man roster. These four players are right-handed pitcher Carlos Carrasco, right-handed pitcher Josh Tomlin, outfielder Michael Brantley, and outfielder Shin-Soo Choo.
Shortly after the World Series players eligible for free agency will officially be removed from the roster. The Indians have three players eligible for free agency: outfielder Kosuke Fukudome, designated hitter Jim Thome, and right-handed pitcher Chad Durbin. None of these players are expected to be resigned in advance of the start of free agency, so even with the activation of the 60-day disabled list players back on to the 40-man roster the removal of the three pending free agents technically puts the Indians roster at 39 players right now.
Obviously one open spot on the 40-man roster is not enough for the Indians to make needed and expected acquisitions via free agency and trade or to add some of their young players from the minors, so they still need to remove a few players from the roster.
Who Stays, Who Goes
Looking at the 39 players on the Indians
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IBI Breaking Newswire


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Since 2009, enforcement of FCPA actions has significantly increased. The Department of Justice has convicted over 50 individuals, and companies have paid approximately $3 billion in fines and penalties. Government...more
- Cross-Border D&O Insurance Enforcement Actions FCPA Federal Contractors Indemnification Clauses Risk Mitigation Suspensions & Debarments Vendors
Based on recent cyber-attacks against the United States Office of Personnel Management (OPM) and its subcontractors, USIS and KeyPoint Government Solutions, it is evident that government entities and government contractors...more
- Best Practices Commercial General Liability Policies Cyber Attacks Cyber Crimes Cyber Insurance Cyber Safety Act Cyber Threats Cybersecurity Data Breach Data Protection Data Security Federal Contractors Information Technology Policy Exclusions
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Small business owners' anxiety levels are in the red zone because of the barrage of news about hacking incidents that target businesses' ongoing operations. While those...more
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Defending the Body: Neutrophils
Editor's note: Physicians have a special place among the thinkers who have elaborated the argument for intelligent design. Perhaps that's because, more than evolutionary biologists, they are familiar with the challenges of maintaining a functioning complex system, the human body. With that in mind, Evolution News is delighted to offer this series, "The Designed Body." For the complete series, see here. Dr. Glicksman practices palliative medicine for a hospice organization.
Life must not only obey the physical and chemical laws of nature, but must also protect itself from many of the other organisms that exist in the environment. Nature contains a multitude of different microbes that, though our senses cannot detect them, are always trying to enter our body so they can multiply. The first line of defense against infection by these microorganisms is the skin and the epithelial tissues that line the respiratory, gastrointestinal, and genitourinary tracts. Deprived of any one of those, our earliest ancestors could not have survived long enough to reproduce. However, if by injury or functional ability, microbes penetrate to the tissues below, then they come up against the second line of defense: the immune system.
In previous articles I've shown that the immune system can be divided into two categories: the innate immune system that each of us is born with and the adaptive immune system which develops over time as we are exposed to the environment. Each of these systems has its unique cells and proteins that are needed for the body to defend against microbial invasion. In my last article I looked at the first responders of the innate immune system and how they act like sentries defending a walled town. Now let's look at the main immune cells in the blood that respond to the call to arms by the sentries and how they do their job to help keep the body alive.
Blood consists of about 55 percent fluid and 45 percent cells, of which there are three main types. The most numerous are the red blood cells (erythrocytes) that produce hemoglobin to transport oxygen to the tissues. The platelets (thrombocytes) are smaller than red blood cells and help the body control bleeding when injury takes place by sticking together and providing a base for fibrin clot formation. Finally, the least numerous but largest cells are the white blood cells (leukocytes), which help to defend the body from infection.
The leukocytes can be divided into two main types: mononuclear agranulocytes, which have uniform nuclei and no granules within the cytosol (lymphocytes and monocytes), and polymorphonuclear granulocytes,which have multi-lobar nuclei and granules within the cytosol (neutrophils, eosinophils and basophils). The former make up about 30 percent of the white blood cells in the blood and the latter about 70 percent.
The lymphocytes are part of the adaptive immune system, which we'll discuss later. The monocytes are basically wandering macrophages within the blood that enter sites of infection and, like the fixed macrophages in the tissues, are one of the first responders that kill invading microbes and process their chemicals to provide important information to the cells of the adaptive immune system.
Of the polymorphonuclear granulocytes, it is the neutrophils that are the main defenders against infection. Let's see how they do their job and what clinical experience tells us about how important they are for survival.
Like red blood cells and platelets, neutrophils are produced in the bone marrow and with maturation move out into the blood. Neutrophils are usually the first immune cells from the blood to come to the field of battle. They are attracted to the war zone by cytokines, which are chemical messengers released from injured tissue and activated mast cells, macrophages, and dendritic cells. The process by which they move into the field of battle and toward invading microbes is called chemotaxis. This involves using specific receptors on their plasma membrane to move toward areas of increasing concentration of these chemicals. It's similar to how a bloodhound moves towards its prey by sensing the increasing concentration of the scent, or a shark to blood. Moreover, the same cells that send out cytokines to attract neutrophils and other immune cells also release chemicals that cause inflammation. Inflammation allows the neutrophils to squeeze through the narrow openings between the cells that line the capillaries into the tissues so they can seek out and destroy the enemy.
Once inside the tissues and brought toward the invading microbes by chemotaxis, the neutrophils activate by using specific receptors on their plasma membrane to attach to specific chemicals on the surface of the intruder. The activated neutrophil usually engulfs the microbe in a process called phagocytosis (phagein is Greek for "to eat"). Once the microbe is inside, the neutrophil releases various chemicals and enzymes to kill and literally digest it. Neutrophils also kill microbes by releasing the chemical contents of their granules into the tissues, in a process called degranulation, where not only the microbes but also host cells may suffer damage.
However, some pathogens have developed the ability to defend themselves from this initial attack by the neutrophils. In later articles I will show how both the innate and adaptive immune systems produce specific proteins to help bolster the effects of the neutrophils to bring about a counterattack. After neutrophils do their job, they usually die and are phagocytosed by macrophages. Dead neutrophils make up most of the cellular content of pus. Finally, like all activated immune cells, neutrophils release cytokines to promote inflammation, attract other immune cells to the battlefield, and increase the metabolism, often causing fever.
The body is constantly being exposed to many different types of microbes. Therefore it must have enough defenders with enough fire power to protect itself from overwhelming infection. The analogy of the inhabitants of a walled town defending themselves from invasion only works up to a point. A town usually faces a finite number of attackers that usually diminish as the battle goes on. However, a microbial infection usually involves a relatively small invading force that, given the chance, is able to multiply rapidly once inside the body. In contrast, neutrophils do not multiply and generally only live a few hours to a few days.
The number of defenders and their ability to move fast enough and have enough firepower to protect against an invading force determined the survival of a town. In the same way, the body must have enough neutrophils that can move fast enough from the blood into the tissues with enough firepower to protect against life-threatening infection. The normal neutrophil count is about 3 to 7.5 billion per liter of blood, but having at least 1.5 billion per liter usually provides an adequate defense against life-threatening infection. Due to their short lifespan, the bone marrow must produce about one hundred billion neutrophils per day to have enough neutrophils in the blood and tissues. That means the body makes about one million neutrophils per second!
Furthermore, to maintain this constant production, support cells in the bone marrow release a cytokine called Granulocyte Colony Stimulating Factor (G-CSF), which attaches to specific G-CSF receptors on the stem cells in the bone marrow, stimulating them to develop into neutrophils.
Finally, in response to infection and inflammation, some immune cells also release G-CSF, which can often result in a doubling or even tripling of the amount of neutrophils. So, although neutrophils cannot multiply on their own (like microbes can), in response to infection and inflammation some immune cells stimulate the bone marrow to increase neutrophil production. This increase makes more defenders available that can be sent to the battlefield. It is by the release of these cytokines that the body not only develops a fever, but also raises the white blood cell count (leukocytosis), the two main tell-tale signs of infection.
However, when it comes to life and the ability to defend against invading microbes, real numbers have real consequences. Clinical experience shows that when the body doesn't have enough properly working neutrophils to track down and kill enough invading microbes, it usually dies. The commonest clinical cause for this is the use of radiation and chemotherapy in cancer treatment, which often reduces bone marrow function and results in a condition called neutropenia.
Severe neutropenia is having a neutrophil blood count less than 500 million per liter and is often associated with a very high risk of septicemia and death. With severe neutropenia, there just aren't enough neutrophils around to patrol the body against intruders. This is like not having enough defenders to prevent invaders from scaling the walls and taking over the town.
In addition to not having enough neutrophils, having too many, as with acute leukemia, where there may be in excess of one hundred billion per liter of blood, can cause problems as well. Remember, leukocytes, like other blood cells, float within fluid. So, just like having too many food particles in the kitchen sink can clog up the drain, so too, having too many neutrophils in the blood can slow down blood flow. Besides taking over the bone marrow and reducing the production of red blood cells and platelets, this complication of leukemia can result in multi-organ failure and death. The mere presence of neutrophils in the blood does not guarantee survival. You not only have to have the right number of them, but they also have to work properly as well. For our earliest ancestors this would have been a matter of life and death.
Evolutionary biologists seek to explain how life came into being but they pay attention predominantly to how it looks, not how it must work within the laws of nature to survive. They may speculate on how neutrophils and the control mechanisms involved in their production must have come into being by chance and the laws of nature alone. But this doesn't take into account that this system is irreducibly complex, requiring cells that can produce G-CSF and ones that have specific G-CSF receptors, so they can be instructed to become neutrophils, and cytokines to allow neutrophils to leave the bloodstream, and with specific receptors move toward their prey.
It also requires natural survival capacity. For our earliest ancestors to have survived long enough to reproduce, this one part of their innate immune system must not only have constantly produced enough neutrophils within enough time, but also must have been able to get them to the field of battle fast enough and with enough firepower to get the job done. What evolutionary biology tries to explain is how the defenders of a walled town came to be where they are, not how there just happen to be enough of them to get the job done and how they do it.
Now that you've seen how some of the immune cells of the innate system work, it's time to look at how its proteins work. After all, a good defense requires many different weapons and strategies. We'll turn to that subject next time.
Image: White blood cells (leukocytes), by Dr Graham Beards (Own work) [CC BY-SA 3.0], via Wikimedia Commons.


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GM may increase dealers on coasts
SAN FRANCISCO – General Motors may add dealers in big metro areas on the U.S. coasts because it expects sales there to grow, two top executives said Saturday.
It's the opposite of the company's stance just two years ago when GM got rid of about 1,700 dealers across the U.S. as it headed into bankruptcy protection.
GM has been losing dealers on the coasts, especially in California, for two decades due to slow sales as people bought more foreign brands. Company officials say GM's poor products also played a significant role.
Mark Reuss, GM's North American president, said Saturday that the company's dealership footprint on the coasts was destroyed by the lack of products, the financial meltdown and GM's 2009 trip through bankruptcy protection.
The company, he said, wants to rebuild the network because its newer models, like the Chevrolet Cruze compact, are starting to sell better in coastal markets, and GM expects growth to continue as it rolls out more new products and the economy recovers.
"We know there's areas where we should be that we're not," said Don Johnson, vice president of U.S. sales. "We didn't have the product. We didn't have the focus. We were irrelevant to California consumers."
GM needs more dealers in the San Francisco and Los Angeles metropolitan areas and will look at other areas on the East and West coasts and around the Gulf of Mexico, the executives said.
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Tijuana Flats
39 Eglin Parkway NE, Fort Walton Beach, Florida, USA, 32548
Serves meat, vegan options available. Tex-Mex fast food chain. Casual atmosphere, order at counter. Reported no meat broth in rice, no dairy in guacamole, and no lard in beans or cooking.
Category: Lacto, Fast food, Take-out, Mexican, Tex-Mex, Non-veg
Reviews (5)First Review by vegeray
not good - Edit
The food is greasy and inconsistent in taste. Guacamole is too salty and the service is little to be desired.
One of my favs - Edit
This place is one of my husband and I's favorite places. When we don't feel like cooking we usually choose to go here. I love the black bean and veggie burritos and I also get tacos with black beans too. There salsa and guacamole are delicious.
Vegan & Family Friendly - Edit
We ended up at Tijuana Flats after the first place we went to didn't have high chairs. So down the road we went and I'm so happy that we did. The staff is polite and vegan-knowledgeable. Most of the items are easily made vegan, even the kids meal.
What we ordered:
Chips and Guacamole
Norritto (burrito bowl) with black beans and refried beans.
Veggie & Bean Burrito (sans cheese)Comes with Chips
Kids meal burrito (refried beans & rice) with apple juice and banana (other option is applesauce.) Comes with chips.
Everything was excellent. Filling and tasty and not a hint of cross-contamination with non-veg items.
The Hot Bar has a lot of great hot sauces. We stuck to the mild ones for the most part. We especially loved the "Slap my @$$ and call me Sally-Sweet" and the "Caribbean Soul Key Lime." Husband tried the Ghost Chile but as we're from New Mexico it wasn't that hot to us.
Also worth a mention, we didn't order them this time, but our server confirmed the banana empanada desert is vegan. Not sure if this includes the caramel sauce or not, but it's nice to know you can finish your meal with something sweet.
The patio is dog friendly (complete with water bowls) and kid friendly (complete with bean bag toss and sidewalk chalk.)
Pros: Vegan friendly staff/ menu, Family Friendly, Dog Friendly (on patio)
Nice, accomodating, veg/canine friendly! - Edit
My family (husband and two dogs, haha) and I have come here to eat multiple times and it has always been very pleasant! Patio seating outside allows dogs, and the waiters were very kind and even brought out treats! Our food was delicious with no traces of meat or cheese. Would recommend!
Vegetarian Concern - Edit
I loved this place. Once we found meat in an item and they were very apologetic and upset. We stayed away for a long time. Many of our veg friends said give it another try. But found chicken or meat in a bean burrito. You hae to be very careful
Pros: vegan items, good , friendly
Cons: not careful, may find meat
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When we talk matchups, the Paul Pierce/LeBron James slugfest rarely gets mentioned, and it's odd. The two have matched up in four of the past five postseasons, and given they are playing the same position with very similar roles on their respective teams, you'd think the NBA fanbase would take better notice. Instead, we're asking for Kobe vs. LeBron in the Finals or checking the calendar for when Deron Williams and Chris Paul match up again.
Yet the best one-on-one battles happen in the playoffs, and these two small forwards have shed enough blood against each other to make a movie.
But in Game 1 of this year's Eastern Conference Finals, the Truth shot 5-for-18 and was nonexistent for most of the night. He played better in the second game (21 points), but ultimately fouled out before he could inflict any memorable damage on Miami and James. LeBron has been a monster, and dropped 32 and 13 in Game 1.
Boston is down 2-0, and it doesn't take a genius to know they better win both games at home. Rajon Rondo won't be scoring 44 points again any time soon, so it's going to fall on Pierce's head. He HAS to outplay LeBron for long stretches in New England, or else this series will be over before we get a defining moment.
But if anyone is able and willing to rise to the occasion against the toughest matchup in the league, it's Pierce. He's done it over and over again in the playoffs for the Celtics. With that, here are the top five best playoff performances of his career.
*** *** ***
5. 2008 NBA Finals, Game 5 at L.A. Lakers
Celtics lose 103-98
Pierce: 38 points, 6 rebounds, 8 assists
Boston might've lost this game, but you wouldn't have known it looking at Pierce. This was probably the weirdest Finals game I've ever seen. No one really wanted to win. Down 3-1, the Lakers knew it was over, and played in somewhat of a trance after the first quarter. And the Celtics knew they were going home for Games 6 and 7. Outside of Pierce absolutely destroying Kobe, Luke Walton, Vlad Ramanovic and everyone else in white, it was a relatively boring night.
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4. 2012 First Round, Game 2 at Atlanta
Celtics win 87-80
Pierce: 36 points, 13 rebounds, 4 assists
No Rajon Rondo. No Ray Allen. Down 1-0 on the road, Boston should've lost this game. Too bad Pierce started almost right from the tip, scoring within mere seconds from the opening jump, and never letting up. "I have a lot of experience, a lot of confidence from being in those moments," Pierce said afterwards. "You believe in yourself, your coach believes in you, your team believes in you, it's a combination of all those things." He capped it all off by Tebow-ing at center court.
3. 2002 Conference Finals, Game 3 vs. New Jersey
Celtics win 94-90
Pierce: 28 points, 19 in the fourth quarter
The Truth has had higher scoring games in the playoffs – take for instance the 40 he dropped on Indiana (plus 21-for-21 from the line) in Game 1 of the 2003 Playoffs – but none of them will be remembered quite like this game will be. Boston came home tied at a game a piece with New Jersey in the Eastern Conference Finals, but found themselves down 21 points before Pierce exploded. It took a tongue lashing from Antoine Walker, but in crunch time, Pierce lit the crowd on fire by continuously driving to the basket – over and over again – on his way to 19 points in the fourth quarter of one of the greatest comebacks in NBA history. I wasn't even a Celtic fan, but living in Boston at the time, I felt like one after this.


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How Additional Medications Free Calls To Your Loved Ones
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The same technology is embedded softphone small devices, known as analog telephone adapter or ATAS. They have become really popular over recent years, along with the quality in the devices has grown dramatically. ATAS basically connect a regular phone at home, located on the one hand, and the other Internet. ATA acts as being a gateway, to translate requirements from cell phone to the SIP that goes through the Internet and, finally, cell phone system, where it is to decode and transmit regular phones.
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Another story Warren often recounts was when we entered this little tiny grocery store we found tucked somewhere in the town. As we entered, the guy turned on the breakers and powered up modest calculator too single light bulb. As soon as we left the little store, everything was turned off again! This reminds me of the ENEL (Italy's electric company) procedure each and every or only two. We would go down to function to settle the bills and tony horton created always a crowded blunder. On day I got a little agitated and was almost in tears, as everyone had cut in front of me and some man came all the way from at the back, guided me together with a desk and had me pay separately. After that, aged gentleman would always get me and serve me first. Warren said it had to do with my chest size.
So function it conserve your funds? VOIP saves money by eliminating the need to use a regular phone line, and make costly Cheapest international calls. In fact if the the receiver is a Skype user calls can be achieved free of charge. Consider using email, it is just like VOIP - free and fast, however voice lets you speak and listen similar to regular phone to any section of entire world.
Newer far better Skype apps will be a boon to small enterprisers and professionals who use actual commitment required every month. We can't wait to see that they take advantage of the iPad and the iPhone several.0 in the months to come.
Using the VoIP system, cheap VoIP calls to India can be made to anyplace lengthy as there is an internet connection. No additional charges have to be paid to make calls and receiving says.


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By Harold Ambler
Contributing Writer
PROVIDENCE – A team of Rhode Island-based researchers has found that dementia patients are at high risk for readmission after hospital discharge.
Publishing their results in the Archives of Gerontology and Geriatrics, lead author Lori Daiello, assistant professor at the Warren Alpert Medical School at Brown University, and her co-authors found that patients with a diagnosis of dementia were nearly 20 percent more likely to be readmitted within 30 days than those without dementia.
The researchers analyzed more than 25,000 admissions to Rhode Island hospitals. All of the patients in the study were Medicare fee-for-service beneficiaries
"People with dementia are quite a vulnerable group when they enter the hospital," said Daiello. "We know that dementia can impair these patients' ability to follow discharge instructions and to report worrisome symptoms. It's critical to recognize and account for a dementia diagnosis when doing the discharge planning process."
Dr. Gary Epstein-Lubow, assistant unit chief of geriatrics at Butler Hospital and a co-author, said that family members play a crucial role when people with cognitive impairment are discharged from the hospital.
"People with cognitive impairment need help to accept hospital care and need even more help after the hospital to be sure that the gains achieved inpatient are maintained," said Epstein-Lubow. "Health care systems can do more of this by improving handoffs to the next clinicians, and equally or more important is the communication with family – because, all too often, it is the family caregiver who has unexpected responsibilities right after the hospital care is complete."
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