text:
Swiss Stocks Fall as Franc Gains; Richemont, Swatch SlideCorinne Gretler
Swiss stocks fell for a second day, paring three weeks of gains in the benchmark index, as Cie. Financiere Richemont SA slumped the most in more than seven months and the franc gained against the euro.
Richemont tumbled 5.6 percent, for the largest decline since June, after the world's second-biggest luxury-goods company reported sales that missed estimates. Flughafen Zuerich AG dropped 2.9 percent after Nomura Holdings Inc. downgraded its recommendation for the stock.
The Swiss Market Index slid 0.4 percent to 7,336.05 at the close of trading in Zurich, for the first back-to-back losses since the start of the year. The gauge has still rallied 7.5 percent in 2013, the best start to a year since the measure was formed in 1988. The broader Swiss Performance Index also slipped 0.4 percent today.
"The SMI had a strong start to the year," said Reto Huenerwadel, senior economist at UBS AG in Zurich. "To the extent that market participants are willing to take more risk, we've seen the franc depreciating against the euro and a rally in Swiss stocks. But it's difficult to see how the rally could go on at this pace."
The franc rose for a second day, gaining 0.3 percent against the euro. The Swiss currency last week depreciated to the lowest level since the country's central bank imposed a exchange-rate cap in September 2011.
Bailout Funds
Euro-area finance ministers, gathering in Brussels today, will begin talks on how to channel rescue funds directly to banks. Policy makers are likely to clash over how and when the 500 billion-euro ($666 billion) European Stability Mechanism can bypass governments. An assessment of Spain, Cyprus and Greece is also expected to feature.
Richemont slid 5.6 percent to 74.30 Swiss francs, contributing the most to the SMI's decline. The owner of the Cartier brand reported third-quarter revenue growth that missed analysts' estimates as demand in the Asia-Pacific region slowed.
Revenue rose 9.3 percent to 2.86 billion euros in the three months through December, the Geneva-based company said today. The 5 percent growth excluding currency shifts missed the 8.9 percent average estimate of 13 analysts surveyed by Bloomberg.
Swatch Group AG, the world's biggest maker of Swiss watches, retreated 1.9 percent to 510 francs.
Flughafen Zuerich fell 2.9 percent to 403 francs, the largest drop since April, as Mark McVicar, an analyst at Nomura, cut the stock to reduce from buy, meaning investors should sell the company's shares.
The volume of shares changing hands in SMI-listed companies was 19 percent lower than the average of the last 30 days, data compiled by Bloomberg showed.


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Call our experts: 888.808.FINE
Custom Stationery from luxury designers!NEW! Wedding Invitations Customize any Address Stamp to match your style!
Select a quantity and printing method. Changes are easily made later.
This pearl white invitation features ample space for all your event details. Shown with optional monogram MON381A. Two color printing is available for an additional charge.

subset: commoncrawl


text:
Create a Social Network
This project received 59 bids from talented freelancers with an average bid price of $3109 USD.Get free quotes for a project like this
Project Budget$1500 - $3000 USD
Total Bids59
Project Description
Hi everyone, my company and I need a social network built. We want it to have the same appearance as [url removed, login to view], but of course, instead of being targeted to companies, it is targeted towards sports teams, players leagues, and all sports in general. I can explain a bit more about what the website needs to do after I hire you, but for now it needs to be kinda like Facebook, but instead of connecting with friends, you connect with teammates, and the teams connect with leagues. That's very brief but it is a little info. The payment is simple, we know that if this website is programmed well, and designed well, it will be a big hit! But we also know that it will take a lot of upkeep. So we are offering for you to work with us a couple hours a week and put in new features, fix bugs, ect...You will be part of the company! You will be making 35% of the sales! Apply and we can talk more! Thanks!
Skills Required
Looking to make some money?
- Set your budget and the timeframe
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- Wall Street Journal
- Times Online


text:
Find the best choice in video poker at William Hill Casino Club. These online casino games are different to casino poker in that you are not trying to beat the dealer – but striving to get the best hand possible to win big. We have designed a casino environment that is inclusive of all types of casino players – so all players can find a game or table that appeals to them.
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Our great range of video poker games includes the likes of Joker Poker, where you can win up to 5000x your initial stake. We also have the ever popular Aces and Faces, where you get a bigger payout if you match four of a kind with aces or jacks, queens and kings. You can also try your hand at 10's or Better, a simple yet fun video poker game with a big 4000x initial stake jackpot. You can find all these great video poker games – and many more besides – at William Hill Casino Club.
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text:
In the U.S., the second phase of mandatory clearing of over-the-counter derivatives goes into effect in June. Market participants warn that many smaller firms might have to suspend their use of OTC derivatives because they will struggle to sign up with a futures commission merchant. The situation could prompt some to shift to interest-rate-swap futures, according to market participants.
Full Story:Risk.net (subscription required)


text:
Jerome Jerome
John Jerome sometimes claims to be retired but can't prove it. He has in the past raced in cars, on skis, and in swimming pools but now lives as slowly as possible in far-western New England and writes books. He is a former magazine editor, advertising copywriter, and columnist for "Esquire and "Outside magazines. His previous books include "Truck, The Sweet Spot in Time, Stone Work, and "Blue Rooms.
"From the Hardcover edition.
There are no products matching the selection.


text:
CRI's new website that seeks to engage, educate, and empower patients and their loved ones to learn more about cancer immunotherapy as a treatment option across numerous tumor types.
Cancer patients, donors, scientists, and other supporters all stand behind the Cancer Research Institute. Read their stories and learn about what motivates each of us to keep fighting against cancer.
By running in a marathon or hosting a bake sale, you can make a real difference for our scientists in the fight against cancer and allow them to bring newer immunotherapies to more patients.
We gratefully accept donations made in memory or in honor of a loved one. Your gift will be acknowledged to whomever you specify.
A $1 million challenge to spur innovative solutions to challenges in cancer immunotherapy research.
Curious about the latest developments in cancer immunotherapy research? Listen in as leading scientists discuss immune-based treatments across numerous cancer types in our free "Cancer Immunotherapy and You" webinar series.
When the Cancer Research Institute was founded in 1953, we knew then that immune-based treatments would transform cancer medicine. In more than six decades since, we've made numerous groundbreaking discoveries that have given more patients new hope today.
Are you a patient or caregiver? Visit our website TheAnswerToCancer.org for more information on immunotherapy for pancreatic cancer.
Pancreatic cancer is the most lethal cancer, and new therapies are urgently needed to impact pancreatic cancer treatment and to extend and save pancreatic cancer patients' lives. Immune-based strategies to treat pancreatic cancer during the early stages of development, as well as new immunological approaches to treat advanced disease, are showing significant promise where other approaches have failed. This page features information on pancreatic cancer and immunotherapy clinical trials for pancreatic cancer patients, and highlights the Cancer Research Institute's role in working to bring effective immune-based cancer treatments to pancreatic cancer patients.
Pancreatic cancer is the fourth-leading cause of cancer-related death in the United States, with a 5-year survival rate of less than 7%. Compared to other cancers, it shows marked resistance to conventional forms of chemotherapy, and there are limited capabilities to diagnose and treat the disease in its earliest stages. No current treatment option has demonstrated long-term benefit in patients with advanced disease who are not eligible for surgery—which represents the majority (80%) of pancreatic cancer cases.
Urgent Need: Pancreatic ductal adenocarcinoma (PDA), which accounts for more than 90% of pancreatic cancer cases, is highly lethal; for all stages combined, the 1- and 5-year relative survival rates are 27% and 7%, respectively, making it the only cancer with an overall 5-year survival rate in the single digits. Even for those people diagnosed with local disease, 5-year survival is only 27%. More than half of patients are diagnosed at a distant stage, for which 5-year survival is 2%.
Incidence and Mortality: Each year more than 53,070 people in the United States will be diagnosed with pancreatic cancer, and more than 41,780 will die. Worldwide, more than 337,000 people will be diagnosed, and more than 330,000 will die of the disease. The incidence of pancreatic cancer is rising, and some reports project that the number of new pancreatic cancer cases and pancreatic cancer deaths will more than double by 2030.
Detection/Diagnosis: Pancreatic cancer is very difficult to detect or to diagnose at early stages of disease. It often develops without early symptoms, there is no widely used method for early detection, and, although some risk factors have been identified (such as tobacco use, family history of pancreatic cancer, and a personal history of pancreatitis, diabetes, or obesity), few patients diagnosed with pancreatic cancer have identifiable risk factors.
Treatment: The only curative treatment for pancreatic cancer is complete surgical resection. Unfortunately, fewer than 20% of patients are candidates for surgery, because pancreatic cancer is usually detected after it has spread. Cancers that cannot be treated with surgery are called "unresectable." For those patients with localized disease and small cancers with no lymph node metastases and no extension beyond the capsule of the pancreas, complete surgical resection can yield 5-year survival rates of 18% to 24%. Approximately 80% of patients who undergo surgery eventually relapse and die from the disease, suggesting a need for effective strategies to eradicate minimal residual disease following surgery to prevent relapse.
Because of the poor prognosis and lack of effective treatment options, for pancreatic cancer a clinical trial is nearly always preferred over existing treatment options for everything except localized tumors that can be removed surgically. Specifically, pancreatic cancer patients are encouraged to participate in clinical trials:
Go to our Clinical Trial Finder to find clinical trials of immunotherapies for pancreatic cancer that are currently enrolling patients.
Several approaches to immunotherapy for pancreatic cancer have shown promise in early clinical trials. These treatments can be broken into 7 main categories: checkpoint inhibitors/immune modulators, therapeutic vaccines, adoptive cell transfer, monoclonal antibodies, oncolytic viruses, adjuvant immunotherapies, and cytokines.
A promising avenue of clinical research in pancreatic cancer is the use of immune checkpoint inhibitors. These treatments work by targeting molecules that serve as checks and balances in the regulation of immune responses. By blocking inhibitory molecules or, alternatively, activating stimulatory molecules, these treatments are designed to unleash or enhance pre-existing anti-cancer immune responses. Several checkpoint inhibitors, targeting multiple different checkpoints, are currently in development:
Nivolumab (Opdivo®): A PD-1 Antibody +/- Ipilimumab (Yervoy®): A CTLA-4 Antibody
Pembrolizumab (Keytruda®, MK-3475): A PD-1 Antibody
Durvalumab (MEDI4736): A PD-L1 Antibody +/- Tremelimumab: A CTLA-4 Antibody
Other Drugs
Cancer vaccines are designed to elicit an immune response against tumor-specific or tumor-associated antigens, encouraging the immune system to attack cancer cells bearing these antigens. Several trials of vaccines, given alone or with other therapies, are currently enrolling patients with pancreatic cancer:
Another major avenue of immunotherapy for pancreatic cancer is adoptive T cell transfer. In this approach, T cells are removed from a patient, genetically modified or treated with chemicals to enhance their activity, and then re-introduced into the patient with the goal of improving the immune system's anti-cancer response. Several trials of adoptive cell transfer techniques are currently under way for patients with pancreatic cancer, including:
Monoclonal antibodies are molecules, generated in the lab, that target specific antigens on tumors. Many monoclonal antibodies are currently used in cancer treatment, and some appear to generate an immune response.
Oncolytic virus therapy uses a modified virus that can cause tumor cells to self-destruct and generate a greater immune response against the cancer.
Adjuvants are substances that are either used alone or combined with other immunotherapies to boost the immune response. Some adjuvant immunotherapies use ligands—molecules that bind to proteins such as receptors—to help control the immune response. These ligands can be either stimulating (agonists) or blocking (antagonists).
Cytokines are messenger molecules that help control the growth and activity of immune system cells.
CRI discoveries and ongoing work in pancreatic cancer research and treatment include:
This hematoxylin and eosin stained slide of a surgically removed (resected) primary pancreatic tumor shows a cluster of immune cells (lymphoid aggregate) observed next to a pancreatic tumor lesion in a patient treated with a GM-CSF vaccine 2 weeks before surgical removal of the primary tumor. Immunohistochemistry of this and similar aggregates found throughout the resected tumor shows CD4+ and CD8+ T cells—aka helper T cells and killer T cells, respectively—with B cells in germinal center-like structures. (Photo courtesy of Lei Zheng and Elizabeth Jaffee, Johns Hopkins University)
Sources: National Cancer Institute Physician Data Query (PDQ), American Cancer Society Facts & Figures 2016, National Comprehensive Cancer Network (NCCN) Guidelines for Patients, ClinicalTrials.gov, CRI grantee progress reports
Updated March 2016
January 31, 2017
December 1, 2016
November 1, 2016
Listen in as Dr. Elizabeth Jaffee discusses the latest immunotherapy research for breast and pancreatic cancers in this 45-minute webinar recording.
Watch Now
Are you a patient interested in enrolling in a cancer immunotherapy clinical trial? Visit our Clinical Trial Finder page to learn what trials you may be eligible for.
Subscribe to our e-updates to receive the latest news about pancreatic cancer immunotherapy.
A donation to the CRI today will help us to fund groundbreaking scientific research aimed at bringing safe and effective immune-based treatments to patients with pancreatic cancer.


text:
NJASA Legal Department Research Services - January 2017
School administrators have an obligation to prevent students from being sexually abused by both current and former employees. Part one of this Administrative Guide discussed the impact of improper sexual relationships on students and the steps chief school administrators should take when presented with information about improper conduct by a staff member. Part two concludes the series by discussing the steps to be taken to prevent harm to other children by former employees who have been accused of inappropriate contact with students.
In addition, School News Briefs reviews three new cases including one case in which the Commissioner held that the standard to prove inefficiency for increment withholding purposes is not the same standard as that for inefficiency tenure charges.
The January 2017 Special Education Bulletin, also reviews three cases including one in which a school district was ordered to reimburse the parents for the placement of a disabled child at an unaccredited, sectarian school because no other placement could provide a FAPE.
Subscribers to the NJASA Legal Research Publication Program can access the publications after inserting their user name and password by clicking here.
To become a subscriber to the NJASA Legal Research Publications Program, click here.


text: Elvin and Helen Gower of Kunkletown brought their 1926 Model T Ford to St. Matthew's UCC's Laymen's Fellowship Strawberry Festival and Car Show. Elvin says he learned how to drive on his grandfather's Model T Ford pick-up so they have a special place in his heart. The car show drew in 136 entries, the largest number they've ever had.


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Lemon Frosted Plum Squares
|Strawberry-flavored gelatin
|6 Ounce, flavored (1 Package)
|1 Dash
|Boiling water
|2 1⁄2 Cup (40 tbs)
|Lemon-lime carbonated beverage
|1 Cup (16 tbs)
|Lemon juice
|2 Tablespoon
|2 Cup (32 tbs), pitted and cut in wedges (9 Pieces)
|Instant lemon pudding mix
|3 3⁄4 Ounce (1 Package)
|Cold milk
|1 1⁄4 Cup (20 tbs)
|Dairy sour cream
|1⁄2 Cup (8 tbs)
|Bibb lettuce
|Apple slice
|Lemon lime carbonated beverage
|1 Cup (16 tbs)
|2 Cup (32 tbs), pitted and cut in wedges (9 Plums)
|Instant lemon pudding mix
|3 3⁄4 Ounce (One 3 3/4 Ounce Package)
|Apple slices
Dissolve gelatin and salt in boiling water.
Cool to room temperature.
Slowly pour in carbonated beverage and lemon juice; stir gently.
Chill till partially set.
Fold in plums.
Pour into 8x8x2-inch pan.
Chill till almost firm.
In mixer bowl combine pudding mix and milk; beat till smooth.
Blend in sour cream.
Spread pudding mixture atop gelatin.
Chill till firm.
Cut into squares and serve on lettuce-lined plates.
Garnish with apple slices atop each square, if desired.
Recipe Summary
Rate It
Nutrition Rank
Nutrition Facts
Serving size: Complete recipe
Calories 2533 Calories from Fat 323
% Daily Value*
Total Fat 37 g56.5%
Saturated Fat 18.9 g94.3%
Trans Fat 0 g
Cholesterol 88 mg29.3%
Sodium 2577.6 mg107.4%
Total Carbohydrates 547 g182.3%
Dietary Fiber 22 g87.9%
Sugars 324.5 g
Protein 35 g69.9%
Vitamin A 504% Vitamin C 195.2%
Calcium 75.9% Iron 56.7%
*Based on a 2000 Calorie diet


text:
Srinarahari from Mysore, India recommends this hotel Posted: Room Quality: 5/5 Service Quality: 5/5 Dining Quality: 5/5 Cleanliness: 5/5
there was no lodge by that name in the described location. It was there 9 years back. Now it NI Hotel. Kindly, arrange to refund my advance immediately otherwise I will....Dr.Srinarahari


text:
I recently went out on my first Tinder date. I asked him out, mostly because he didn't open with "Can I spread Nutella all over your body," which yes, some other gentleman did propose. We had both right-swiped each other (Tinder speak for approving the person to contact you) and begun texting shortly after. He had two jobs, loved biking and burritos — hey, I like one of those things, too! — and he seemed really driven. There were small red flags, like when I suggested he look at something on Reddit, he said he wasn't interested because he didn't like wasting time on the Internet. That's literally all I do, but whatever, we could get past this.
To be perfectly honest, I'm flawed too: I don't drink alcohol (a deal-breaker for many young daters), sometimes I Febreze myself instead of showering, and I have no desire to go skydiving, ever. But I also have a great job, an OK sense of humor, and I've been told I'm cute by people other than my mother. So who's to say we couldn't be a match, right? Well, here's what happened. This is completely true.
When I Saw His Profile Pictures
This guy was cute. I confirmed it with my co-workers, who looked at his picture when I passed it around the office shortly before I left for the date. (What if I disappeared? They needed to know who I was last seen with. He was a stranger, after all.)
Source: MGM [1]
When He Showed Up Looking Homeless
Oh, goodness. His thinning hair was greasy, his sweatshirt was baggy, and his shoes were dirty. He looked like the poor man's version of the least flattering picture on his profile. I started to question my decision to wake up a half-hour early to do my hair up all cute.
When He Told Me He Says Yes to Every Girl on Tinder
He asked me how I Tinder, and I genuinely didn't even know what that meant. He went on to tell me his strategy is to say yes to every girl (he doesn't even look at the pictures) and strike up a conversation. That really made me feel special. But also, maybe I was the shallow one because I look at the pictures? Such internal conflict.
When I Started to Think Maybe He Was High
Why was he staring at me like he wanted to lick my face? Was there Nutella on it?
When He Told Me About the Time He Woke Up Bleeding
We started talking about the fact that I don't drink, and he goes, "Yeah, sometimes I think I should stop, too." When I ask why, he starts telling me about the time he woke up in an unfamiliar place with blood all over his hands. What do you even do with that?
Source: MGM [2]
When He Asked If I Wanted to Split the Cheese Plate
OK, I don't always need a guy to pay for me. Having said that, it's a nice gesture, especially on the first date. Usually I make a move for my wallet, and the guy will go, "No, this is on me," and I'll shyly put away my wallet and say, "Thank you," genuinely appreciating the free meal. Instead, we walked up to the counter and he says, "So we'll split this?" That's $6 I'll never get back.
When a Child Street Performer Started Singing Love Songs Next to Us
Look, it's enough pressure to go on a date with a stranger. I don't need some kid judging our chemistry.
Source: A24 Films [3]
When He Started Talking About His "Experimental Phase"
I know it's a double standard that girls get an experimental phase and guys don't, but I didn't make the rules. In fact, it didn't even bother me so much that he kissed a man, but it did bother me that he had a propensity to flirt with men just to get free drinks. His story about getting drunk with a male co-worker and making out with him (and "maybe more") only to tell him later that he was "totally straight" and doesn't want anything to do with the poor guy bothered me the most.
When He Said He Didn't Want a Full-Time Job Because It Would Be Selling His Soul
You're right, working part-time at CPK is way better.
When He Brought Up His Former Fiancée
At this point, bringing up his past relationship didn't even register on my radar of why this date was a fail. Though, in case you were wondering, they dated for five and a half years, he still loves her, and he let her keep the $4,000 Tiffany ring. Whatta guy.
When He Told Me What a "Good Guy" He Is For Not Sleeping With His "Slut" Boss
I can't even.
When I Said Goodbye and Thanks For the Cheese
Why did I say that? HE DIDN'T EVEN PAY FOR THE CHEESE.
When He Texted Me 10 Minutes Later
The most offensive part of this whole experience was him telling me, "For a Tinder date, you're someone that I really liked." Really? Because I hate you.
When I Got Home
I literally crawled into the fetal position. Then I checked my Tinder, where a new guy had messaged me asking if I was into "butt stuff." I'm starting to think this app isn't for me.


text:
Popular music app Shazam has announced a partnership with the biggest electronic music digital retailer, Beatport.
If you have a smartphone, then you most likely know what Shazam is (and you probably have it too). It's the app we all use when we're listening to sets and radio shows from our favorite DJs to get those sought-after IDs that plague our lives, to the tracks we're dying to know.
With this new partnership, Shazam will have access to Beatport's entire catalogue of music. That's A LOT of music!
Shazam's director of music and content Will Mills revealed that 31 of the top 100 most tagged tracks from last year were dance music. He said, "From Ibiza to LA to Tokyo and beyond, fans of electronic dance music will now be able to experience more of the dance tracks they love every time they use Shazam when they go out."
Beatport's CEO Matthew Adell added, "Our partnership also gives DJs and producers exposure to an enormous audience of potential new fans."
It was about time these two companies joined forces. Now get to Shazam-ing!
Photo Credit Getty Images


text:
- Coma
- Low blood pressure
- Seizures
What causes coma, low blood pressure and seizures? 3 possible conditions
See a list of possible causes in order from the most common to the least.
This condition is considered a medical emergency. Urgent care may be required.
Learn about carbon monoxide poisoning and what causes it. Find information on carbon monoxide symptoms, diagnosis, treatment, and prevention.
This condition is considered a medical emergency. Urgent care may be required.
An adrenergic bronchodilators overdose is when you take too much of a certain kind of asthma medication.
Medullary cystic kidney disease (MCKD) is a rare condition in which small, fluid-filled sacs called cysts form in the center of the kidneys. These cysts scar the kidneys and cause them to malfunction. In order t...
Please consult a healthcare professional if you have health concerns.
Click to add a symptom to your list
- Top Symptoms
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Results 1 to 2 of 2
- 12-18-2012, 09:56 AM Thread Author #1
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Just switched from iphone 4S, please help.
Hello, I just changed over from a 4S to an S3 and thus far it has been tough to make the change. I have a couple of issues that I'm hoping can be resolved on this new phone. Any help would be greatly appreciated.
1. I have no idea if there is an update to Jelly Bean, I've read that there is but my built in updater says nothing is available. Can I update with factory software?
2. I used Samsung's Easy Phone Sync program to move over contacts, pictures, etc. The only problem is that I had a lot of text messages on my iPhone and have let it sync overnight and it has only finished with one person's text thread. Everytime I try to go into that thread I can scroll up about one screen and then it crashes the ap. I have removed the 200 text limit so that I can keep all my old text messages, but it appears that the built in messenger does not archive old texts like the iphone does. Is there any way to keep all my texts, or archive them like the iphone? Or is the Galaxy limited to having only 200 texts in storage. Seems like a pretty big drawback so far.
3. I had to manually stop the Easy Phone Sync process, because it drained my battery from full to zero overnight, and I'm guessing it uses a ton of computing power. Is this most likely the sync application and not just normal battery life for the S3?
4. The front of the phone seems extremely hot all the time, and this is fresh out of the box with auto-dim enabled, is this phone always this hot?
5. The built in browser also seems very slow to react to button pushes and clicks on the device, is this normal?
Please let me know any tips and tricks for an Android noob, I would like to love this phone but these issues are a little strange. Please let me know what I should do with the text syncing process, since I manually stopped it after one text thread, and I have 4 years of texts that function fine on my iPhone. I know that most people will say delete them, but that doesn't seem like a great indicator of the Galaxy compared to the 4S if the 4S stores them with no problem and the Galaxy can't. Is there any way to keep them? If not, then will I constantly only be able to have a running limit of 200-500 texts saved?
Thank you.
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Re: Just switched from iphone 4S, please help.
I think if you do a search in this forum you'll find TONS of tips as a new Android user.. I had an iP3G for 4 years and have had my GS3 for about 5 months now and couldn't imagine returning to the dinky little iPhone. That said, let me see if I can throw out some ideas:
1. Re: Update. Since I'm a PC guy and I have no idea whether you're PC or Mac, let me just say that you first need to install Kies on your computer. Once it's installed, fully charge your battery. Then you'll need to take the USB cable that came with your charger and plug into the PC with Kies installed and let it recognize your phone. It may take a couple of tries, but it will happen. Once it recognizes your phone it will show you the latest update available for Android version 4.1.1. You click to install it and just sit back and wait until its finished.
2. Re: Easy Sync. I don't save text messages though photos are usually saved in a folder in iTunes which can be imported to your phone. I have a Scandisk 32 gb Class 10 MicroSD which is where my photos are saved. Contacts are best imported into a Gmail account which will sync with your phone.. That's the best solution. Remember you're a Google user now, so let go of the Apple thinking, LOL
3. Re: Temperature. Your phone shouldn't be hot, but since you're saying the Easy Sync is running non-stop, that's probably the reason. You can also go to:Support - AT&T Cell Phones SGH-I747 | Samsung Cell Phones and either live chat or call Samsung with any questions. They're really great both chat and phone. Also make sure you set up a Samsung account.
4. Re; Browser. The stock browser sucks in my opinion. Since I use Chrome on my PC I immediately installed Chrome and set up the Chrome to Phone sync. Now all my bookmarks, tabs, etc. sync on my phone. I also have Dolphin browser installed which totally rocks too.
5. I honestly don't know what to tell you about storing text messages since I don't save mine. Some other more savvy Android users will probably be able to help, or just chat with a Samsung rep
Also, I would install the SwiftKey 3 keyboard, Visual Voicemail app (and have ATT set it up for you), Juice Defender and Aquamail instead of the stock email app..but that's just my opinion. I liked the look and feel of the stock email app but it doesn't support HTML viewing. Aquamail free allows you to set up 2 accounts and works great; the stock Gmail app will automatically notify you of any emails too.
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text:
The Book of Genesis, Illustrated by R. Crumb
From Creation to the death of Joseph, here is the Book of Genesis, revealingly illustrated as never before.
This eagerly awaited graphic work retells the first book of the Bible in a profoundly honest way. Peeling away the theological and scholarly interpretations that have often obscured its most dramatic stories, R. Crumb - using actual text word for word - has imagined the Bible as it really was. Now, readers of every persuasion - Crumb fans, comic book lovers, history buffs, and believers - can gain astonishing new insights from these harrowing, visceral, and even juicy stories. Crumb's "The Book of Genesis" reintroduces readers to Adam and Eve's Eden, Noah's Ark, Sodom and Gomorrah, and the Pharaoh's Egypt. Using clues from the text, Crumb fleshes out the parade of biblical originals: from the sensitive dreamer Joseph to the crafty Jacob, to the still-fetching Sarah, to God Himself. The result, four years in the making, is a tapestry of extraordinary detail, the finest work of Crumb's legendary career. MORE
BoingBoing Video: Paging Through R. Crumb's Book of Genesis
Fora Video: R. Crumb in conversation with Francoise Mouly (Art Director, New Yorker)
Book Details
224 pages, Hardcover
October 2009
Jacket Illustration: R. Crumb


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This is your resource to discuss support topics with your peers, and learn from each other.
Hi All,
I am trying to show text which has Arabic and Numeric content using Graphics paint drawText method. It is behaving wierdly. Below is the code
String arabic ="اختبار"; g.drawText(" 2.5 " + arabic , 5 , 5); g.drawText(" 2.5B " + arabic , 5 , 40); g.drawText(arabic+" 2.5 " , 5 , 75); g.drawText(arabic+" 2.5B " , 5 , 100);
And below is the output
I need to have Arabic content on Left of Digit. (First case works fine). But when I have letter for example 2.5B, then Arabic content is coming on Right always.
Can we do something about this?
Thanks and regards,
Solved! Go to Solution.
08-29-2012 05:38 AM - edited 08-29-2012 05:39 AM
I think only option in this case is to draw both Arabic and alphanumeric content seperatly.
g.drawText(arabic , 5 , 75); g.drawText(" 2.5B ", 50 , 75);
The better way is add the text in sublayout of a manager and use the localization for the language.
and in that manager you can use LOCAL_AWARE_LAYOUT. So that it will automatically adjust the text according to the language.
Yes I think this is also a good way of handling.
08-29-2012 06:29 AM - edited 08-29-2012 06:29 AM
Can we see the Field definition that you have added this paint() to to get your output. I am wondering if there are some DrawStyle or text alignment style bits that are set that you could perhaps set another way and get different results.
Also can you tell us what OS level you are developing for and testing on.
08-29-2012 07:18 AM - edited 08-29-2012 07:19 AM
Hi Peter,
In my POC i didnt use any DrawStyle. I am just overriding paint to check in a Screen. But after you pointed out I tried DrawStyle.LEFT, DrawStyle.RIGHT giving the same results.
Simulator OS i am testing on is 126.96.36.1991 (9810).
I guess when it is coming to Arabic text some auto handling is being done in combined string (As Arabic is Right to Left language) which we avoid by seperate drawText or using sublayout. There may be another better way of doing this other than these.
"I guess when it is coming to Arabic text some auto handling is being done in combined string"
I agree, I was trying to figure out where it came from.
It is kind of great that it will reverse the order of the words, but kind of strange that it does not do it consistently.
The DrawStyle styles that I think are significant are LEADING and TRAILING. Also I think the locale of the device/Simualtor could be important too. But I don't know.


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- Eddie B and Harry Fraud provide their new collaborative project as a free stream.Nov 12, 2013 | 1,056 Views 14 Comments Nov 12, 2013 at 05:39pm
- HOTTTTTEddie B gets production from his frequent collaborator Harry Fraud and an assist from Sean Price and Term on this new cut off the upcoming "Paper Piff & Polo" project arriving November 12th. Pre-order it on iTunes.95 Views 3 Comments Nov 8, 2013 at 02:16pm
- Eddie drops an EP, entirely produced by Harry Fraud. The project features guest appearances from The Kid Daytona, Shabaam Sahdeeq, Chace Infinite and Adrian Lau. The instrumental version of each track is also includedOct 14, 2013 | 966 Views 6 Comments Oct 14, 2013 at 04:12pm
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- HNHH's "Underrated Audio" puts you on not-too-mainstream music you might have missed from the past week.Apr 9, 2013 | 107 Views 4 Comments Apr 9, 2013 at 04:48pm
- HOTTTTTEddie B and Harry Fraud linked up for a project, "Horsepower," which is out now on HNHH. This particular cut features Shabaam Sahdeeq & Maffew Ragazino.88 Views 1 Comment Apr 8, 2013 at 03:02pm
- Eddie B and producer Harry Fraud have joined forces for this effort, "Horsepower." All tracks, of course, produced by Fraud, with appearance from Matthew Ragazino, AG Da Coroner, Meyhem Lauren, Action Bronson and more.Apr 8, 2013 | 10,076 Views 11 Comments Apr 8, 2013 at 03:00pm
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- MarvelousEddie B Feat. Action BronsonHOTTTTTEddie B and Harry Fraud grab Action Bronson for the second leak off their upcoming collaborative EP "Horsepower." The EP is dropping at SXSW.89 Views 10 Comments Mar 7, 2013 at 01:14pm
- HOTTTTTBy Steve KerryHarry Fraud's Surf School artist Eddie B has some projects in the works including the "Horsepower" EP dropping soon. Here is the first cut with la musica de Harry Fraud.66 Views 2 Comments Feb 21, 2013 at 05:47pm
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Let us know when your receive great advice so we can thank our lawyers and point others with similar questions in the right direction.Got it!
I got in a fight with my Baby's father and left him. I left a lot of stuff there, including my car and the title. He had the keys and refused to give them to me. So I just left it there for a while cause the tags were dead anyway. Later, I get calls from the girl demanding I put the car in her name. I told her that I WOULD NOT EVER sign the title and if she put it in her name, I would have her arrested. I thought nothing of it cause I figured she didn't want to get in trouble. Then I saw my car with West Virginia tags (I'm from Va), come to find out this girl registered it in her name with out my permission, AT ALL. I don't want who signed it to get in trouble, only her(his mom will say she signed it so she won't get in trouble and I don't want her in trouble.
What is it that you are trying to accomplish? Simply getting your car back, getting someone "in trouble" or both? Forging a signature on a vehicle title (or other legal document) is a crime. It appears that the car must be registered (in WV) - how long did you leave it? It isn't clear what rights you may have without knowing all the facts. You may want to consult an attorney before doing or saying anything else about this matter. Good luck.
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Forging the title is a crime. Registering the vehicle with a forged title is also a crime. However, there are other ways to get a title if the vehicle has been abandoned. Contact Virginia DMV to find out how your car's title changed hands before assuming or doing anything.
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text: 10 Jan 2014 Castle hotels: The Fab Five Previous slide Next slide 4 of 5 View All Skip Ad Kinnettles Castle, near Dundee Fancy slumbering in a 19th century Scottish Baronial Castle? Head north of Dundee to Kinnettles Castle for fairytale turrets, little windows peeking from stone walls, and fly fishing and clay pigeon shooting, if the king-of-the-castle bug really catches on. Also available for exclusive hire and events. Double rooms from £149, including continental breakfast (£9 extra for cooked Scottish breakfast); (01307 820354; kinnettlescastle.com ). Back to image


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Microsoft Streamlines Azure Preview Portal Experience
This month's update makes the cloud management portal easier to navigate, use and customize.Microsoft's cloud-powered, DevOps-enabling Azure Preview Portal has a new look and feel after the November 2015 update. The changes are aimed at helping customers better manage and monitor their Azure cloud-powered application environments. The newest release improves how users interact with the portal, allowing them to drill down to their desired tools, dashboards and controls in a more intuitive manner. One example is the new resource browsing experience, explained Leon Welicki, a Microsoft Azure program manager, in a company blog post. "When you are browsing through a list of resources and click on a resource, the browse blade is now automatically collapsed to a list that displays only resource names," he stated. "If you close the resource blade, then the browse blade is restored (it expands and shows all the columns again). This experience makes it easier to both navigate through a list of resources and focus on one resource." Browse blade lists are now wider and can accommodate more columns. For example, the classic virtual machines (VMs) view can also display a VM's size, DNS name and VIP status. The browse blade can also now be used as a springboard for other tasks.
"You can take action on a resource directly from a browse blade," Welicki said. "For example, if you want to connect to, start or stop a Virtual Machine you don't need to open a resource blade, you can just do it directly from the Virtual Machines list."
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Woodworkers Connection to Wood Market News
WMIA honors Safety Speed Cut
Monday, 19 July 2010 00:00
Safety Speed Cut has won the 2010 Partner of the Year award, presented by the distributor division of the Woodworking Machinery Industry Association.
Bigger crowds come out for Kitchen & Bath Industry Show
Written by Jennifer Hicks Monday, 19 July 2010 00:00
The National Kitchen and Bath Association's 47th annual Kitchen & Bath Industry Show (KBIS) drew more than 37,000 attendees April 16-18 to Chicago's McCormick Place. It featured nearly 700 exhibitors showcasing their latest products.
Baltimore show see sales on the upswing
Written by Jennifer Hicks Monday, 19 July 2010 00:00
The Baltimore Fine Furnishings & Fine Crafts Show had its second appearance at the France-Merrick Performing Arts Center/Hippodrome Theater on the weekend of May 1-2. Exhibitors say their success had nothing to do with luck and everything to do with strategic marketing.
IWF 2010 hopes for late surge
Written by Jennifer Hicks Monday, 14 June 2010 00:00
While campaigns and promotions for IWF 2010 are in the works, those behind the scenes are enthusiastic about the show's expanded educational seminar program and the array of new machinery and supplies expected to be presented by exhibitors.
Exhibitors buoyed by Philadelphia show
Written by Jennifer Hicks Monday, 14 June 2010 00:00
The 16th annual Philadelphia Invitational Furniture Show experienced a vibrant turnout, with numbers slightly up from last year. The show took place March 26-27 at the Cruise Ship Terminal in the Philadelphia Navy Yard. Many exhibitors reported that their sales expectations were met or exceeded and they plan to return next year.
Page 51 of 79


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From the Miami Herald:
A federal criminal probe is under way into whether the owner of a South Florida anti-aging clinic illegally sold controlled substances to high schoolers in addition to major league ballplayers and other professional athletes, the Miami Herald has learned.
This after Porter Fischer, the former Biogenesis employee, gave interviews in which he said it wasn't just baseball players who patronized the clinic.
Source: Craig Calcaterra, NBC Sports Hardball Talk


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Spending 2 nights at the Ptarmigan Inn this week and while this hotel offers many "pros", the "cons" mean I would not return nor recommend it to friends without some caveats.
. The Ptarmigan Inn is very well located, especially for travelers without a car. On the main drag but a 5 minute walk from the busy center. Perfect.
. The staff is very friendly and helpful. At check-in, I asked about fares for Roam buses and was given a free pass good for my entire stay. I was also upgraded to a premium room (with fireplace and jacuzzi tub). Just cause.
. The room I was given is large and faces Banff Avenue. It is a bit rustic to my taste but everything works fine and the bed is wonderful.
. I had read reviews so knew the Ptarmigan Inn deosn't have a/c. Silly me thought I wouldn't need it since it gets quite cool at night here (5 C last night). Well... My room is boiling hot! For some reason, there is little to no air circulation during the day even though both windows are wide open. At night, to avoid hearing road traffic, I have to close the windows so no cooling down then either. There is a wobbly floor fan in the room but, let's be honest, all it does is move hot air around. If the Ptarmigan isn't willing to invest in a/c (which several guests wish they would judging by the reviews), seems to me the least they could do is install ceiling fans above the beds which would be slightly more efficient than what they have now.
. The breakfast room is dark and dreary. Food is ok but not replenished often/ quickly enough so you have to constantly ask for more bread/bacon/eggs/coffee...
. When I checked in, I specifically requested a quiet room since I have low/no tolerance for noise. Why then has a mediocre at best musician been strumming his guitar and howling underneath my window for the last hour?
In short, if you don't mind a stuffy room, dark breakfast space and bad live music, this is the place for you! But until such a time as the Ptarmigan starts offering a comfortable, bright, airy and quiet experience to its guests, I won't be returning.
- Official Description (provided by the hotel):
- - Located on Banff Avenue, one short block from downtown Banff- Includes Full buffet breakfast with a made to order omelette station- Indoor hot tubs, sauna, steam and fitness equipment- The Meatball Pizza and Pasta- 134 cozy hotel rooms- The Sundance and Atrium function rooms for small to mid-size - meetings/receptions- Complimentary wireless internet access in all guest rooms- Heated underground parkade with free parking (first come basis)- Complimentary Roam Bus passes for the Banff transit system. ... more less
- Reservation Options:
- TripAdvisor is proud to partner with Booking.com, Hotels.com, Cheap Tickets, Travelocity and Priceline so you can book your Banff Ptarmigan Inn reservations with confidence. We help millions of travelers each month to find the perfect hotel for both vacation and business trips, always with the best discounts and special offers.
- Also Known As:
- Banff Ptarmigan Hotel Banff
- Ptarmigan Inn Banff


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B2B: Education
Community College
Creating awareness of business training programs available to the business community.
Our Work:
We developed a strategic marketing plan based on competitive analysis, surveys and interviews.
The College received value from the following:
- Increased focus – The research more clearly defined the target market parameters, so that it could avoid inefficiencies and pinpoint where it's marketing dollars should go.
- Understanding of buyer values – The research showed what criteria were of most importance to businesses in selecting a training program.
- Higher ROI – The College had a marketing plan, including a competitive analysis, clear communication points, tactical plan and budget, making its return on marketing investment go farther.


text: It's Finally Here! Mommy Books | May 2016 I'm so excited to announce the launch of my very first parenting book. The book is now available for pre-orders (more details below). I first came up with the idea for this book after struggling with Read More Tags: baby self-feeding, ezpz happy mat, purees, contest, book, nancy ripton, melanie potock


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NOBODY saw this one coming! John Huarte was from California, a prized prospect from an emerging Catholic prep school, Santa Ana Mater Dei, which would later produce Heisman honoree Matt Leinart of the Cardinal and Gold of USC. But Huarte's talents went unrecognized by Joe Kuharich and Hugh Devore. As a soph in '62, Huarte escaped the sideline, and Kuharich's dour gaze, long enough to complete 4 of 8 passes for an un-Heisman foreshadowing 38 yards. When the '63 season opened, under "interim" Coach Hugh Devore, Huarte was buried behind Dennis Szot, Frank Budka and Sandy Bonvecchio. The Irish faithful would certainly see ...Read More »
Notre Dame Heisman Trophy Winners
Paul Hornung
Paul Hornung's path to the Heisman Trophy was filled with intrigue, surprise and adventure, and finished in what is arguably the most controversial Heisman Trophy Award. Hornung was a legendary schoolboy athlete at Flaget High in Louisville. Jim Murray, the iconic LA sportswriter, once described Louisville, the captive of the tobacco and bourbon cartels, as "America's Bar Rag." Notwithstanding, Hornung eventually became a member of the High School Hall of Fame. Frank Leahy was in his twilight when Hornung's recruitment began. Hornung, along with Flaget High teammate Sherrill Sipes, came up on a recruiting visit for the 1952 USC game. But when the ...Read More »
John Lattner
It seemed that Notre Dame's Heisman Trophy winners were following a Westward sojourn. Angelo Bertelli, from Springfield, MA, was the first and next was John Lujack of Connellsville in Western PA. Next was Leon Hart from Turtle Creek, a Pittsburgh suburb and just northwest of Connellsville. The Fighting Irish Heisman caravan then shifted to Oak Park, a near west suburb of Chicago to Fenwick High and John Lattner. Fenwick was run by the Dominicans and was named after a Bishop Fenwick from Cincinnatti. Fenwick, which provided five recruits to Hugh Devore's masterpiece recruiting class of 1963, became one of the lead tributaries of the Chicago ...Read More »
Leon Hart
Leon Hart was a big player for Notre Dame. He was actually the BIGGEST Heisman Trophy Winner of all time. Hart was born in Pittsburgh, and was recruited to Notre Dame from Turtle Creek, PA, just Southeast of Pittsburgh. Hart's recruiting had some drama. Leahy had assigned the wonderful Moose Krause to recruit Hart and he had been on him like basmati on rice. Hart had not yet visited Notre Dame. The normally sturdy Krause was felled by a horrific, near pneumonic bout with a cold, and could barely move. His wife was providing cough syrup, chicken soup and tender loving care. The ...Read More »
Johnny Lujack
John Lujack was born and raised in Connellsville, Pennsylvania, southeast of Pittsburgh. Lujack was a four sport athlete at Connellsville, and was an RKG, graduating as both the Valedictorian and Senior Class President of Connellsville '42. He was a "phenom" on and off the field, and the local gentry, a few months after Pearl Harbor, encouraged him to attend West Point. But young Johnny had spend Saturday Autumn afternoons glued to his radio listening to the exploits of a civilian team, the University of Notre Dame. When Lujack arrived, he was soon the backup to Angelo Bertelli, and in the kind of thing ...Read More »
Angelo Bertelli
The Heisman Trophy was first awarded in 1935 by New York's Downtown Athletic Club as the "Downtown Athletic Club Trophy." John Heisman, the former coach at Georgia Tech, was the athletic director of the DAC and supervised the award program. After Heisman's death in 1936, the DAC was renamed the "Heisman Memorial Award Trophy," conveniently remonickered as the "Heisman Trophy." It was first awarded to that bellwether of the University of Chicago Maroons, Jay Berwanger, in 1935. Yale players won the next two. In each case one trophy is awarded to the player and one to his school. So the ones you see displayed in ...Read More »
Tim Brown
Notre Dame was in a 24 year Heisman drought, its longest since the award was established in 1935. Then Tim Brown ended the drought when he won his Heisman in 1987. Notre Dame's first 6 winners were Caucasians. Four had attended legendary Catholic High Schools. Neither was true with Tim Brown. But Tim Brown may have been unique in that he might have been influenced by Notre Dame's Bowl Appearances, which began after the '69 season, with the '70 Cotton Bowl. When Notre Dame broke the 45 year self-imposed boycott of the bowls, it did so in Dallas. In the ...Read More »


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PHP auto download / upload - repost
- Status Closed
- Budget N/A
- Total Bids 3
Project Description
I'd like to have a script can do these:
Have a manager that allow me to input :
page / rss
option to auto grab IMDb info or not.
which site is going to post.
And the script have these functions:
Auto download torrent file from the page / rss i provided, you can use preg_match_all or anything you preferred.
If it is a rar file, UnRAR the file, remove all attached files like: [url removed, login to view] or .url kind of advertisements.
Auto grab screenshots and contains my watermark or domain name and upload to the image host i provided.
Auto ReRAR the file into splits by the size I provided.
Add my domain name at prefix on the file.
For example: [url removed, login to view]
Auto upload those files to the filehost on my account, for example: Fileserve, FileSonic,Hotfile,RapidShare,MediaFire.
Auto grab download links from filehost.
Auto grab IMDb info if the file is a move and upload poster to the image host i provided.
(I can provide IMDb info grabber and you need to save those IMDb info)
Auto post formality Title, IMDb info, video info, screenshot to WordPress using XML-RPC or anything you like.
This script must work on Linux server.
This script can do multitask, which means can download / upload 5 or more torrent on the same time.
I prefer this script based on PHP, but you can use python if you like.Get free quotes for a project like this
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Pharmaceutical Innovation
Frederic M. Scherer
Harvard University - Harvard Kennedy School (HKS)
July 2007
KSG Working Paper No. RWP07-004
AEI-Brookings Joint Center Working Paper No. 07-19
This article, written for the forthcoming Handbook of the Economics of Technical Change, surveys the costs, risks, and challenges encountered in the discovery and development of superior new pharmaceuticals. The changing methods by which drugs are discovered, the links between companies and academic science, the changing character of public regulation, and the sharp rise in the cost per new approved drug are analyzed. Determining which new drugs are both efficacious and safe poses classic statistical decision theory problems. Why patents are so important to drug developers is explored. A rent-seeking theory of new drug development is proposed to rationalize the high gross margins but only slightly supra-normal returns on investment realized by pharmaceutical companies, and the economic welfare implications are investigated.
Number of Pages in PDF File: 59
Keywords: Welfare, Health Care, Social Policy
Date posted: February 6, 2007
Suggested Citation
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Alien Disclosure with aside of NSA disclosure
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Originally Posted by
Come on. Look at it. Does it really look human to you? It has a fin coming out of its skull for christ sake!
But you're arguing from a position of complete ignorance. How many human foetal skeletons have you seen? How many human foetal skeletons have you seen with severe deformities, such as dwarfism? How many mummified foetal skeletons have you seen? How many skeletons with abnormal cranial processes have you seen? Ever seen John Merrick's skeleton?
I'm not a specialist in mummified bodies, neither are you, and certainly neither is Steven Greer. He's an osteopath, not a paleontologist. The point is that none of the three of us are fit to judge whether this is one of the bizarre shapes into which the human form can be distorted. We can only go on the most superficial of appearances.
One of the recent previous 'aliens' turned out to be a skinned squirrel monkey. Another hoax. But a layman would look at it and say it couldn't possibly be a monkey - a naive judgement because most people (including me) can't possibly be educated on what skinned or foetal or deformed or injured or stitched-together creatures actually look like.
So, what you need is someone like a forensic surgeon. Like the one who examined it in 2007 and concluded it was a human foetus:
El feto humano de ?Sirius? - CSI
Or someone from the Horniman museum in London, who deals with foetal skeletons:
Atacama 'alien' mystery is no mystery | Zygoma
Bung it through googletranslate.
Or you could go for a DNA analysis, which I've already reported. Here's the report:
and here's the summary:
Reconstruction of the mitochondrial DNA sequence and analysis shows an allele frequency consistent with a B2 haplotype group found on the west coast of South America, supporting the claimed origination of the specimen from the Atacama Desert region of Chile. Sequence analysis definitively rules out the specimen as an example of a New World primate.
Greer has his own DNA analysis - unless he's misinterpreting the one he received - but then he is the producer of the Sirius documentary and stands accused of skimming off the profits - not by sceptics but by other UFologists:
EXOPOLITICS: Politics, Government, and Law in the Universe: Sirius documentary: Reported project financial improprieties and "Dead Man's Trigger" fabrication by Dr. Steven Greer undercut UFO/ET and New Energy mission
Seeing as Greer makes an income from UFO documentaries, there is a conflict of interests here.
What the hell?
Steven Greer dedicated his career to declaring aliens real.
Honestly, if you want to argue alien life-forms have been discovered on earth, you don't want to be using Steven Greer to back you up. Leave him off your team.
230 strict press @ 220; bodyweight+187 X 4 dips @ 180; 403 front squat @ 210; 10 000 push-ups.
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More than any other species, humans have evolved a remarkable ability to manipulate the physical environment with their hands, resulting in an extraordinary transformation of our culture and our planet. This ability co-evolved with an enormous expansion of the neocortex and an increase in the number of areas of the cortex associated with hand use and hand-eye coordination. Although manual abilities in non-human primates cannot match those of humans, they are nonetheless impressive and rely on similar brain mechanisms. Indeed, most of posterior parietal cortex in both human and non-human primates comprise a network that includes areas 5 and the anterior intraparietal area (AIP), and is devoted to reaching, grasping, manipulation and bimanual coordination, as well as transforming sensory information into a coordinate system in which these actions can be initiated. Three overarching goals of the present proposal are: to assess the role of areas 5 and AIP in executing three well-defined tasks that require a monkey to perform natural (although complex) manual and bimanual behaviors under both visual and non-visual guidance. This will be accomplished by permanently lesioning areas 5 or AIP in different animals and examining the resulting behavioral deficits that arise following lesions to these fields. The second goal is to determine if spared areas in the network that generates complex manual behaviors can compensate for permanent loss of a cortical field. This will be accomplished by utilizing a microfluidic cooling device to reversibly deactivate areas 2 and AIP in the animals with area 5 lesions, or deactivate areas 2 and 5 in the animals with AIP lesions. The final goal is to examine the coordinated activities of areas 5 and AIP for generating complex manual behaviors by rapidly and reversibly deactivating area 5, AIP or 5+AIP ipsilaterally and bilaterally in the same animal and observing resulting behavior. In all cases, functional inputs of the deactivated region will be determined. Our lesions and reversible deactivations will be quantified using a combination of thermal recordings, electrophysiological, behavioral indications, and 3D stereological data reconstructions. These studies build on our previous data on behavioral and cortical plasticity following lesions to posterior parietal cortex. Our proposed studies will define the coordinated role of areas 5 and AIP in normal cortical circuits as well as their capacity to compensate for restricted posterior parietal lesions.
Humans are highly dexterous animals, and bimanual dexterity is critical for even the most rudimentary tasks that humans perform daily. The importance of these abilities is particularly marked when parietal cortical areas that lie at the core of these abilities are lost due to stroke or lesions, and severe deficits such as optic ataxias, dystonias, choreas, and neglect occur. The proposed studies will examine posterior parietal areas involved in manual behaviors, and the behavioral deficits that arise when these areas are lesioned. We will also determine the extent of behavioral recovery and the cortical plasticity that underlies this recovery following progressively larger virtual lesions to posterior parietal cortex.
|Goldring, Adam B; Cooke, Dylan F; Baldwin, Mary K L et al. (2014) Reversible deactivation of higher-order posterior parietal areas. II. Alterations in response properties of neurons in areas 1 and 2. J Neurophysiol 112:2545-60
|Cooke, Dylan F; Goldring, Adam B; Baldwin, Mary K L et al. (2014) Reversible deactivation of higher-order posterior parietal areas. I. Alterations of receptive field characteristics in early stages of neocortical processing. J Neurophysiol 112:2529-44
|Campi, Katharine L; Collins, Christine E; Todd, William D et al. (2011) Comparison of area 17 cellular composition in laboratory and wild-caught rats including diurnal and nocturnal species. Brain Behav Evol 77:116-30
|Krubitzer, Leah; Campi, Katharine L; Cooke, Dylan F (2011) All rodents are not the same: a modern synthesis of cortical organization. Brain Behav Evol 78:51-93
|Campi, Katharine L; Krubitzer, Leah (2010) Comparative studies of diurnal and nocturnal rodents: differences in lifestyle result in alterations in cortical field size and number. J Comp Neurol 518:4491-512
|Zumer, Johanna M; Nagarajan, Srikantan S; Krubitzer, Leah A et al. (2010) MEG in the macaque monkey and human: distinguishing cortical fields in space and time. Brain Res 1345:110-24
|Campi, Katharine L; Bales, Karen L; Grunewald, Rebecca et al. (2010) Connections of auditory and visual cortex in the prairie vole (Microtus ochrogaster): evidence for multisensory processing in primary sensory areas. Cereb Cortex 20:89-108
|Padberg, Jeffrey; Recanzone, Gregg; Engle, James et al. (2010) Lesions in posterior parietal area 5 in monkeys result in rapid behavioral and cortical plasticity. J Neurosci 30:12918-35
|Krubitzer, Leah (2009) In search of a unifying theory of complex brain evolution. Ann N Y Acad Sci 1156:44-67
|Zhu, Zhao; Zumer, Johanna M; Lowenthal, Marianne E et al. (2009) The relationship between magnetic and electrophysiological responses to complex tactile stimuli. BMC Neurosci 10:4
Showing the most recent 10 out of 41 publications


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Science & Medicine, Natural Sciences, Society & Culture, TechnologyFollow
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Whether the topic is popcorn or particle physics, you can count on BrainStuff to explore -- and explain -- the everyday science in the world around us.
February 8th, 2010
Episode 533 of 1094 episodes
Mood rings claim to reflect changes in your emotional state -- and, in a way, they do. Discover the science behind mood rings in this episode of BrainStuff.
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Hi Rose,
I'd be very happy to send you a piece! It might not be until next year, but I think it's important for other people to have this one, so I don't feel so guilty if mine croaks.
I'll try to contact you off-forum to make sure I'll be able to get ahold of you whenever I get one ready.
Thanks, Tom
Hi Tom
I for one would be delighted to grow this one if and when you care to part with some of it. Would be glad to pay for an increase and postage.
Rose Kinnard


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This review is from: PLANTRONICS GameCom 380 3.5mm Connector Circumaural Over the ear headset
Pros: Still sounds better than I would imagine
Cons: Very uncomfortable, The sound adjustment button on the headset is too sensitive. The mic isn't a noise cancelling headset.
Other Thoughts: I took an egg from my previous review as I couldn't update the old one. The headset is very uncomfortable especially after a few hours. The mic picks up everything, not clearly but as a high pitched squeaking sound or is too low without mic boost.READ FULL REVIEW
This review is from: Creative Sound Blaster Z 70SB150200000 5.1 Channels 24-bit PCI Express (x1, x4 or x16) Interface Sound Card
Pros: Sound is crisp and clear. Voice modulation is fun. Music has never sound better.
Cons: Installation was a little more complicated than it should have been. Like others mentioned it doesn't sit flush in my motherboard but still works fine after it's in. The connections need to be adjusted by twisting the cables of my mic before it works.
Other Thoughts: While the card sounds great. Scout mode doesn't work that well in a few games. Installation and cable issue are also a slight problem. Not something I would expect from a sound card. Still It works where it counts.READ FULL REVIEW
This review is from: PLANTRONICS GameCom 380 3.5mm Connector Circumaural Over the ear headset
Pros: The sound and mic quality is impressive especially for the price. Material feels solid if that's any indication of build quality.
Cons: The comfort level isn't that great. the ear cups are a little small and the headset itself is a little tight; granted it is new and they haven't been broken in yet.
Other Thoughts: I haven't had time to properly test these but games, music and movies sound decent and that's coming from the integrated sound card. While I don't love the comfort (coming from a corsair vengeance 1500) This is a steal at $50 hopefully they hold up over time and they break in well. Will update over time if any issues occur.READ FULL REVIEW


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[10:01] Download Bleach memories of nobody sub esp parte 6 de 9
January 27, 2010
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Posts tagged with Ux
The hierarchy of user experience components
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Earlier this month, I was lucky enough to spend a week or so in Japan and there were several bits of everyday and unassuming design that struck me.
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A day in the life of... VP User Experience at Huge
This week, we're spending a day in the life of a UX professional within an innovative agency.
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