text:
|Publication number
|Publication type
|Application number
|Publication date
|Jul 29, 1980
|Filing date
|Jun 2, 1977
|Priority date
|Feb 8, 1974
|Also published as
|Publication number
|Avraham Patchornik, Abraham Warshawsky, Matityahu Fridkin, Rami Kalir
|Original Assignee
|Yeda Research And Development Co. Ltd.
|Export Citation
|BiBTeX, EndNote, RefMan
|Non-Patent Citations (3), Referenced by (4), Classifications (40)
|External Links: USPTO, USPTO Assignment, Espacenet
This is a division, of application Ser. No. 545,220, filed Jan. 29, 1975 now U.S. Pat. No. 4,085,261.
The present invention relates to novel ion exchange agents and to a process for preparing these. Various polymeric substances were prepared hitherto, which contain certain desired functional moieties, adapted to carry out a specific activity. According to the methods used hitherto, such polymeric agents are prepared by a sequence of steps, and generally there take place certain undesired side-reactions, which result in cross-linking side-reactions and in undesired physical properties of the products. It is stressed that the novel process of the present invention results in substantially improved products, which have advantageous physical and chemical properties. The advantageous properties of the products obtained according to the present invention are a direct result from the method of preparation of the ion-exchange agents. It is one of the main features of the present invention to prepare the novel ion-exchange resins by activating a comparatively small molecule, carrying the desired chemical function, and to attach this to the polymer backbone of a predetermined polymeric carrier. The activation of the small molecule and its chemical bonding to the polymer substantially eliminates undesired side-reactions, and the product is obtained in a much improved form and has an enhanced degree of activity and specificity compared with similar agents prepared by the conventional sequence of reactions.
The products according to the present invention can be obtained in solid or in liquid form, as desired for certain specific purposes. There may be used a solid polymer backbone, or there may be used long-chain aliphatic compounds having a terminal functional group as carrier, and in the latter case liquid products are obtained.
The novel ion-exchange agents according to the present invention may be used for a wide variety of uses, depending on the functional moieties built into the molecule. They are effective agents for carrying out certain chemical reactions, such as acylations and the like; certain ion exchangers are effective agents for the selective removal of certain metal values from solutions of same; some may be used as ion exchange membranes, etc. Some of the products based on long-chain compounds can be used for liquid/liquid extractions, as their solubility in aqueous solutions is a very low one. Other and further features of the present invention will become apparent from the following description.
In our copending U.S. application Ser. No. 511,687, now U.S. Pat. No. 3,974,110, there is described and claimed a process for preparing certain reagents useful for effecting reactions of organic synthesis, of the general formula ##STR6## wherein
Z designates the ##STR7## part of a polymeric backbone of a polymer like polystyrene, a copolymer comprising polystyrene and a comonomer like divinylbenzene, butadiene and other copolymers comprising styrene; or the aliphatic moiety of a long-chain aralkyl compound having a terminal phenyl or alkyl;
n is an integer of from 1 to 8, inclusive,
R designates oxygen or sulfur;
X designates nitro, carbonyl, carboxyl, cyano-carbalkoxy or a carboxamido group which may be substituted on the nitrogen atom, or a halogen atom, wherein Y is -H or a non-interfering substituent, and corresponding compounds with a naphthyl group instead of the ##STR8##
The present invention relates to the preparation of further reagents of similar structure, but which are useful for certain uses not contemplated in our said first patent application.
The novel products of the present invention are prepared by chemically binding an activated chemical moiety to a polymer backbone, the term "polymer backbone" designating a solid polymer or a long-chain compound. The reaction can be schematically represented, by the reaction sequence ##STR9## Wherein P designates the polymeric backbone as hereinbefore defined, which in the case of solids can be a polystyrene polymer of the type ##STR10## or a similar copolymer, such as for example with 2% D.V.B. or in the case of liquids it designates a long-chain compound, such as for example dodecyl benzene or the like, of the formula ##STR11## In the above X designates halogen such as --Cl --Br or --OH or --OR and R--CH2 -- designates the desired functional moiety attached to the polymer backbone.
Weak acid and weak base ion exchange resins can be prepared by reacting a polymeric backbone, as defined above, with a chloromethylated chloro-nitro-benzene or with chloromethylated nitrobenzene, respectively, as shown schematically in the following reaction sequence: ##STR12##
The above weakly acidic or weakly basic agents can be used as ion exchange resins.
Non-selective ion exchange agents according to the present invention can be converted into effective chelating agents by means of the Fries rearrangement: ##STR13##
The 8-hydroxy-isoquinoline polymer can be esterified as above, and after the Fries rearrangement and conversion to the oxime there are obtained polymeric chelating agents useful in the removal of the recovery of metal values from solutions. The reaction sequence is schematically as follows: ##STR14##
A further type of reagent was prepared by the reaction sequence set out in the following: ##STR15## wherein
R1 designates --H, alkyl or aryl;
X designates alkyl, aralalkyl, halogen, nitro, carboxyl, carboxaldehyde
R" designates --H, alkyl or aryl including substituted aryls.
Similar polymeric agents were prepared by conventional methods and it was found that the ones prepared by the reaction sequence according to the present invention had a higher degree of activity as evident from loading characteristics of the resin, (See U.S. Pat. No. 3,974,110) and that the physical shape and stability of the agents according to the present invention was much better. They were used for repeated sequences of metal removal and were found not to deteriorate.
To a solution of 1.3 g aluminum chloride in 10 ml nitrobenzene there was added 1.7 g 4-nitrobenzyl chloride and 2 g of Xe-305 (polystyrene in bead dorm, Rohm & Haas, USA). The mixture was maintained at a temperature of 65� C. during 72 hours. At the end of this period of time the product was poured on 20 ml of a methanol/HCl mixture (1:1, Conc. HCl), washed with 20 ml of methanol and dried at 80� C. during 5 hours. A crop of the desired product of 3.0 g was obtained. It had a nitrogen content of 4.53% by weight.
To a solution of 14 g stannous chloride hydrate in 20 ml ethanol and 20 ml concentrated aqueous hydrochloric acid there was added 3 g of the polymer obtained in Example 1. The mixture was maintained at a temperature of between 80�-90� C. during 20 hours, the resin was filtered off, washed with a warm mixture (1:1) of ethanol and conc. HCl, with 1 N HCl, with water and with acetone. The product was dried, and the nitrogen content was 4.59% and chlorine content was 6.35% by weight.
The product of Example 2 was reacted in its hydrochloride form with phosgene at 60�-70� C. for 2 hours. The phosgene was driven off with a stream of nitrogen, the polymer was filtered off and washed with dry ether. A quantitative yield of the desired product was obtained.
The polyiscyanato substituted polymer reacts quickly with nucleophiles. Thus, for example, 2 g of the polymer eliminated quantitatively 1 mmole benzylglycine from a solution thereof in 10 ml chloroform.
The polyisocyanato polymer was reacted with hydrazine (2 g of the polymer with 2 g hydrazine in dioxan during 1 hour), yielding a quantitative yield of the corresponding semicarbazide. Analysis: nitrogen: 7.05%; chlorine: 0.51% (residual).
To a solution of 10.4 g aluminum chloride in 120 ml nitrobenzene there was added 19.1 g 3-nitro-4-chloro benzylchloride followed by 16 g of Xe-305 resin, and the mixture was maintained at 90� C. during 3 days. The resin was poured on a methanol/hydrochloric acid (1:1, conc. Hcl) mixture, washed with methanol, with dimethyl-formamide, methanol, and with water. A crop of 20.7 g of dry product was obtained having a nitrogen content of 1.82% by weight.
5 g (3-nitro, 4-hydroxy) benzylated polystyrene cross-linked with 2% divinylbenzene of mesh size 200-300 was converted into the acetate by leaving in a solution of excess acetic anhydride and pyridine in 50 ml methylene chloride until the resin lost its yellow color. It was filtered off, washed with methylene chloride and desiccated overnight over phosphorus pentoxide under a high vacuum. The thus obtained (3-nitro, 4-acetoxy) benzylated polystyrene was left in a solution of 1.3 g aluminum chloride in 25 ml nitrobenzene at 65� C. for 24 hours. The product was poured on a methanol/hydrochloric acid mixture (1:1, conc. Hcl), filtered off, washed with methanol, with water, with methanol and dried. The yellow product shows a carbonyl at 1695 cm-1.
By the same procedure a similar resin was prepared, starting with macroporous Xe-305. It had a nitrogen content of 2.55% by weight.
2 g of dry chloromethylated polystyrene (Xe-305) were reacted with 1.2 g of 8-hydroxyquinoline and 1.35 g aluminum chloride in 20 ml nitrobenzene at 70� C. for 20 hours, during which time the hydroxyquinoline dissolved. The resin as filtered off, washed with methanol: with hydrochloric acid (1 N), with sodium hydroxide (0.5 N), with water, with acetone and dried. There was obtained a crop of 2.0 g of the desired product which had a nitrogen content of 2.4% by weight.
According to a preferred embodiment, there are reacted 2.5 g aluminum chloride. 2.4 g 5-chloromethyl-8 hydroxyquinoline and 2.0 g of Xe-305 polystyrene resin in 10 ml of nitrobenzene. The reaction was carried out at 60� C. and during 20 hours. The resulting resin was filtered off, washed with HCl/methanol (1:1, conc. Hcl), with methanol, water, methanol and ether. The dry product had a nitrogen content of 1.79%. A crop of 3.0 g was obtained.
The resulting 8-hydroxyquinoline resins can be loaded with amino acids and this can be used for the synthesis of peptides. 1.1 g of the polymer obtained in the present example in its hydrochloride form was reacted with 10 ml of a solution of 5%, triethylamine in chloroform until it lost its yellow color, filtered off, washed three times with chloroform and introduced into a solution of 0.8 g BOC-alanine in 25 ml dimtehylformamide. The reaction mixture was cooled to 0� C., 0.8 g dicyclohexylcarbodiimide (DCC) was added and left to stand overnight. The resin was filtered off, washed and dried. The loading, as determined by the benzylamine method, was 0.7 mmole/g.
A comparison of the resins obtained according to Examples 6 and 7 shows that the resin obtained according to Example 7 is mechanically stable and colorless after neutralization while that of Example 6 is colored and decomposes upon prolonged storage.
To a solution of 1.8 g aluminum chloride in 100 ml nitrobenzene there was added 2 g of Xe-305 polystyrene polymer; the reaction mixture was brought to 60� C. and during 48 hours there was added dropwise a quantity of 1.8 g 2-acetyl-4-chloromethyl phenol in 100 ml nitrobenzene. After stirring for additional 20 hours the polymer was poured into HCl (2 M), filtered off, washed with methanol, with water, with methanol and dried. A crop of 2.4 g of the desired product was obtained, having a content of 1 mmole -OH groups/g polymer; IR absorption at 1640 cm-1, (KBr).
To a solution of 1.7 g aluminum chloride in 10 ml nitrobenzene there was added 2.3 g of chloromethyl-2,4-dichloro-6-acetyl phenol (isomeric mixture) and 2.0 g Xe-305 resin. The mixture was kept at 70� C. for 48 hours, poured on hydrochloric acid (2 M) and the resin was filtered off, washed with methanol, with water, with methanol and dried. A quantity of 2.35 g of the desired product was obtained.
1 Millimole of 3-nitro-4hydroxy-benzyl chloride was reacted with excess of toluene in 1.8 M aluminum chloride in 20 ml of nitrobenzene at 65� C. for 20 hours. The product was diluted with toluene and washed with hydrochloric acid (1 N), water, and the nitrobenzene was removed by steam distillation leaving an oily substance which crystallized upon standing. IR: 1690 cm-1 ;
NMR: 2.3 ppm (3H) absorption of methyl; 4.2 ppm (2H) absorption of methylene.
6.2 g (25 mmoles) dodecylbenzene and 5.7 g of 3-nitro-4-hydroxy benzylchloride were reacted with 3.6 mmoles aluminum chloride in 20 ml nitrobenzene as set out in Example 10. There was obtained a yield of 8.9 g of an oily substance. The IR and NMR spectra were in accordance with the expected formula.
1 g 5-Chloromethyl-8-hydroxyquinoline and 1 g cyclododecylbenzene were reacted with 1 g aluminum chloride in 10 ml nitrobenzene at 60� C. during 3 hours. After dilution with 40 ml of chloroform the product was washed with water, the chloroform was removed and the product crystallized from nitrobenzene. There was obtained 1.2 g of yellow crystals. The NMR and IR spectra confirm the expected formula.
10 g of Xe 305 polystyrene were added to 13 g 3-nitro-4-chlorobenzyl alcohol and 10 g aluminum chloride in 50 ml benzene. The reaction mixture was left at 70� C. for 3 days, poured on ice-water washed with methanol, hydrochloric acid (1 N), methanol, and dioxan and the product was dried. There was obtained 14.3 g of a colorless polymer containing 7.0% chlorine.
10 g of the product of Stage A were refluxed in 40 ml hydrazine hydrate (98%) and 60 ml 2-ethoxyethanol. The reflux was effected during 1 hour and after this period the polymer was filtered off, washed with water, with dioxan, methanol, ether and dried. The product contains 0.4% Cl, and 5.4% nitrogen.
The product of Stage B was mixed with 50 ml concentrated hydrochloric acid and 50 ml dioxane and stirred at room temperature for 20 hours. The polymer was filtered off, washed with water, dioxan, methanol, ether and dried. The desired benzhydroxytriazole polymer (BHT) was obtained in quantitative yield. Nitrogen content: 5.2%
A quantity of 5 g polystyrene (Xe 305 Rohm & Haas) was reacted with 10 g benzhydrol in a 1.8 M solution of aluminum chloride in nitrobenzene (20 ml). The reaction was carried out at 75� C. during 20 hours. The reaction mixture was worked up as in Example 1 and there was obtained 0.9 g of the desired product, 2 mmole/g of the polymer.
In a similiar manner, 5 g of polymer were reacted with 5 g of chlorobenzyl chloride to give 6.6 g of 4-chlorobenzylated polystyrene containing about 2 mmole chlorine per gram of polymer.
A quantity of 1.2 g of 3-pyridyl carbinol in 15 ml of 1.8 M aluminum chloride in nitrobenzene was reacted with 2 g Xe-305 during 3 days at 80� C. The polymer was poured on methanol, filtered off and washed with HCl methanol, aqueous methanol, methanol and ether. A crop of 2.6 g of the desired product was obtained which contained 3.6% nitrogen.
A quantity of 1.2 g 3-pyridyl carbinol in 15 ml 1.8 M aluminum chloride in nitrobenzene was reacted with 10 ml of toluene during 3 days at 80� C. The reaction mixture was poured on HCl/ice and extracted with toluene. The organic phase was washed with water, dried and the solvent was evaporated. The desired product was obtained as viscous oil, containg 8.5% nitrogen.
The preparation was carried out as in Example 8, but with 2-formyl-4-chloromethyl phenol.
The preparation was according to Example 8 and a similar yield of the desired product was obtained.
The acetoxy derivatives of the phenols were prepared by leaving them in a methylene chloride solution of acetic anhydride (from 1:1 to 1:2), and pyridine (1 to 10%), until decolorization has taken place. The resins were filtered off, and washed with methylene chloride. The liquids were washed with water, concentrated hydrochloric acid, water, and the solvent was evaporated. The samples were left in a dessicator under vacuum, over phosphorus pentoxide, for a period of 20 hours. Other esters were prepared in a similar manner.
The rearrangement was effected at a temperature in the range of between 45�-100� C., preferably at about 65� C., by leaving the esters in a nitrobenzene solution of aluminum chloride. Good results were obtained with a 1.8 M aluminum chloride solution by leaving for about 20 hours. The resulting polymers were filtered off, washed with methanol, concentrated hydrochloric acid, methanol and ether.
The liquids were diluted with ether (about 5 ml per 1 ml of liquid), washed with concentrated hydrochloric acid, water and the solvent was evaporated. All the liquid products could be identified by the presence of acetylic hydrogens in the NMR spectra. The acetylic hydrogens were in the region of 2.0-25 ppm and there exists the typical shift of the 1750 cm-1 acetoxy absorption to the 1690-1700 cm-1 aromatic ketone absorption. In addition the corresponding oximes and dinitrophenol derivatives were prepared. The following acylated derivatives were prepared:
(3-Nitro-4-hydroxy-5-acetyl) benzylated polystyrene of both the 2% D.V.B.-polystyrene type, and Xe-305.
Oxime: % N 2.7; DNP: % N 5.4
(3-Nitro-4-hydroxy-5-acetyl) benzylated toluene
(3-Nitro-4-hydroxy-5-acetyl) benzylated dodecylbenzene
5-(7-Acetyl-8-hydroxyquinoline) benzylated polystyrene
5-(7-Acetyl-8-hydroxyquinoline)-benzylated cyclododecylbenzene
(3-Nitro-4-hydroxy-5-benzoyl) benzylated polystyrene
(3-Nitro-4-hydroxy-5-p-nitrobenzoyl) benzylated polystyrene
The oximes were prepared starting with the acylated polymers (containing about 4 mmole acyl groups per 2 g of polymer). These were refluxed with hydroxylamine hydrochloride. Good results were obtained by using 10 ml of an ethanolic solution containing 1.4 ml (10 mmole) triethylamine and 0.7 g (10 mmole) hydroxylamine hydrochloride and the reflux was effected during 20 hours. The polymer was filtered off, washed with warm ethanol, with dilute acid and with water.
Liquid oximes were prepared by the same procedure; the product was taken up in benzene, washed with dilute acid and with water. Upon evaporation of the solvent, the desired products were obtained as oily substance.
The products showed the typical IR-absorption in the region of 1660-1640 cm-1 with the disappearance of the carbonylic band at 1690 cm-1.
In this manner the following oximes were prepared:
A. Oxime of (3-Nitro-4-hydroxy-5-acetyl) benzylated polystyrene (Xe-305 polymer: analyses 4.28% N).
B. Oxime of (3-Nitro-4-hydroxy-5-acetyl) benzylated dodecylbenzene (1.8% N).
C. Oxime of (7-Acetyl-8-hydroxy-quinoline)-5-benzylated polystyrene) (analysed 2.74% N).
D. Oxime of (4-Hydroxy-3-acetyl) benzylated polystyrene (analyses 1.61% N).
E. Oxime of (2,6-dichloro-3-acetyl-4-hydroxy and (2.4-dichloro-5-hydroxy-6-acetyl) benzylated polystyrene (analyses 1.28% N).
F. Oxime of (7-Acetyl-8-hydroxyquinoline) benzylated cyclododecylbenzene.
G. Oxime of (4-hydroxy-3-acetyl) benzylated dodecylbenzene.
H. Oxime of (4-hydroxy-3-Formyl) benzylated dodecylbenzene.
I. Oxime of (4-hydroxy-3-formyl) benzylated polystyrene.
The following aqueous solutions were tested:
a. 2.1 g/l Cu as copper sulphate, 0.5 M Na2 SO4, pH 1.3
b. 2.1 g/l Cu as copper sulphate, 0.5 M Na2 SO4, pH 2.12
c. 2.1 g/l Cu as copper sulphate, 0.5 M Na2 SO4, pH 2.72
d. 1.525 g/l CuSO4 ; pH 2.42
0.22 g/l Cu(NH3)4 SO4, PH 9.5
f. 2.1 g/l FeCl3, pH 2.8
g. 1.45 g/l FeCl3 in conc. phosphoric acid
The extraction was effected by shaking the solutions for 2 minutes in a separatory funnel with solutions of the reagents in chloroform at 1:1 ratio. The phases were separated and the organic phase was washed with 0.01 N sulfuric acid. After this the stripping was effected by means of 2 M H2 SO4 at a 1:1 ratio (by volume). The results are given in Table No. 1. The analysis was by means of atomic absorption spectrometry.
Solutions (d) and (e) were used for copper, (f) and (g) for iron. The tests were conducted as follows: a resin bed was prepared by inserting about 2 g of dry resin into a column of 10 mm diameter. The solutions were passed at a rate of 1 ml/minute, the resin was washed with 0.01 N H2 SO4 and then stripped by means of 2 M H2 SO4. The results are given in Table No. 2.
______________________________________Reagent % of No. ofEx. No. reagent solution A:O pH % Extraction______________________________________15/F 5 a 1:1 1.3 7615/F 5 b 1:1 2.12 8115/B 5 a 1:1 1.3 9015/B 5 b 1:1 2.12 10015/B 5 e 1:1 9.5 9915/G 8 d 1:2 2.42 3015/G 8 e 1:1 9.5 10015/G 8 f 1:1 2.8 015/H 6 d 1:2 2.4 1215/H 6 e 4:1 9.5 5715/H 6 f 1:1 2.8 021/d 5 a 1:1 2.4 8821/d 5 a 5:1 2.4 8821/d 5 e 5:1 9.5 10______________________________________
TABLE 2:______________________________________Absorption of Copper and Ironby Chelating ResinsResin acc. toExample No. Metal Solution pH Loaded mg/g resin______________________________________ 7 Cu d 2.42 127 Fe f 2.8 37 Fe g 0.615/C Cu d 2.42 6.315/C Cu e 9.5 9.715/C Fe f 2.8 1.115/A Cu d 2.42 0.215/A Cu e 9.5 5.315/A Fe f 2.8 0.915/i CU d 2.42 0.715/i Cu e 9.5 1115/i Fe f 2.8 1.215/D Fe g -- --15/D Cu d 2.42 015/D Cu e 9.5 5______________________________________
The resin used was that prepared according to Example No. 7 A quantity of 1 g of the resin was stirred in 10 ml of Solution (d) of Example 16, at a pH of 2.42. Aliquots were removed and tested. The resin was then separated and stripped by means of 10 ml 2 M sulfuric acid.
TABLE 3:______________________________________Rate of Absorption and Elution Loading StrippingTime (min) Conc. of Solution (ppm)______________________________________1 830 --5 570 90010 -- 91015 450 96025 -- 1120Loaded: 9 mg total stripped 11.2Resin: Ex. No. 7______________________________________
A quantity of 2 g resin prepared according to example 7 was stirred in 100 ml of Solution (e) of Example 16 of pH 9.5. The stirring was carried out as indicated and after this period of time the resin was washed and stripped with 10 ml of 2 M sulfuric acid. The results are given in Table 3:
TABLE 3:______________________________________Time conc. (ppm) in solution(min) Loading Stripping______________________________________0 220 --13 -- 9705 -- 10506 190 --10 -- 120015 150 --50 110 --______________________________________
The preparation was effected as in Example 7, but starting with 20 ml toluene instead of 2.0 g of Xe-305.
The work-up was as follows: Water was added, the organic phase was washed with water, dried and after this excess of solvent was removed under reduced pressure.
The preparation was as in Example 8, but starting with 20 ml of toluene. The reaction mixture was worked up as in the preceding example.
A solution was prepared, containing 5 g of the above reagent per 100 ml toluene. The thus obtained solution was used at a volume ratio of 1:1 to extract U3 O8 from an aqueous solution of same containing 1 g/l uranyl sulfate. The extraction was at a pH of 2.0 and 80% of the uranyl ions were extracted.
In a manner similar to that of Example 15, the oximes of the compounds
a. (4-hydroxy-3-formyl) benzylated polystyrene;
b. (4-hydroxy-3-formyl) benzylated toluene;
c. (8-hydroxyquinoline) 5-benzylated toluene and of
d. (4-hydroxy-3-acetyl) benzylated toluene
were prepared.
Solutions of the compound of Example 21(d) were used for extracting metals according to Example 16. A 5% solution of the reagent was used.
With Solution a, at a A:O ratio (defined in Example 16) of 1:1 at pH 2.4 an extraction of 88% was obtained.
The same system, but at A:O of 5:1 gave the same extraction.
Solution No. 5 at an A:O ratio of 5:1 at pH 9.5 gave an extraction of 100%.
|Degering, "An Outline of Organic Nitrogen Compounds," p. 176 (1950).
|Flett, Chemistry and Industry, Aug. 6, 1977, pp. 641-646.
|Morrison & Boyd, "Organic Chemistry," pp. 376-382 (1973).
|Citing Patent
|Filing date
|Publication date
|Apr 3, 1991
|May 31, 1994
|N.V. Union Miniere S.A.
|Metal extraction by ion exchange
|Apr 28, 1997
|Oct 23, 2001
|Warner Lambert Company
|Rapid purification by polymer supported quench
|Mar 13, 2001
|Jan 14, 2003
|Warner-Lambert Company
|Rapid purification by polymer supported quench
|Apr 3, 1991
|Nov 14, 1991
|S.A. Acec-Union Miniere N.V.
|Metal extraction by ion exchange
|U.S. Classification
|546/179, 564/265, 564/266
|International Classification
|Cooperative Classification
|European Classification


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Proliferative Retinopathy in Diabetes Tied to Cerebral Microangiopathy
December 20, 2013 (Healio) - Cerebral microbleeds, or microangiopathies, were more prevalent in patients with type 1 diabetes and proliferative retinopathy, researchers wrote in Diabetes Care.
Jorn Woerdeman, MD, of the department of internal medicine at VU University Medical Center in Amsterdam, and colleagues examined 33 patients with diabetes and proliferative diabetic retinopathy (PDR+), 34 patients with diabetes but without retinopathy (PDR?) and 33 controls who underwent MRI to assess cerebral microangiopathy and ischemic damage.
"Our results show that cerebral microbleeds, in contrast to ischemic small vessel disease, are more prevalent in PDR+ patients relative to the other groups," researchers wrote. "The associations between cerebral microbleeds and peripheral microvascular function in skin [have] not been reported before and support the hypothesis that cerebral microbleeds are part of a generalized microvascular disorder, not limited to peripheral organs, such as the eyes and renal system."
Cerebral microangiopathy was identified in 11 patients. Six patients had one microbleed, four had two and one patient had eight microbleeds, according to data.
They found that cerebral microbleeds, but not ischemic damage, were more prevalent in PDR+ patients (n=7; 21%) vs. PDR? patients (n=1; 3%; P=.01) vs. controls (n=3; 9%; P=.02). The researchers also reported a trend across groups for the lowest baseline capillary density in PDR+ patients (P=.05), according to data.
Capillary recruitment was impaired in patients who had cerebral microangiopathy compared with patients who did not (P=.04).
"More research in larger samples is needed to confirm and expand these findings," researchers wrote.
Disclosure: The researchers report no relevant financial disclosures.
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University News Breastfeeding trends good news for new mothers
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There is no "average" pattern or set of rules when it comes to breastfeeding according to a recent study published in the journal Breastfeeding Medicine.
Assistant Professor Jacqueline Kent, from The University of Western Australia's School of Chemistry and Biochemistry, said the most common reason for new mothers to give up breastfeeding was that they felt they had an insufficient milk supply.
But this perception may be based on a comparison with bottle-fed babies, whose feeds are more regulated than breastfed infants. Some breastfed infants prefer frequent snacks day and night while others take fewer, larger feeds.
"We found that from the first to the third months of life, although babies tended to decrease their feeding frequency, they were actually increasing the amount they took during each session while their 24-hour overall intake remained the same," Assistant Professor Kent said.
"Health professionals working with new mothers can give them confidence that changes in breastfeeding behaviour are not an indication of insufficient milk supply, but are more likely due to an increase in stomach capacity of the baby and part of a normal, healthy breastfeeding relationship."
Professor Kent has spent many years studying the biochemistry and physiology of lactation and breastfeeding in babies, working closely with Winthrop Professor Peter Hartmann, who is internationally recognised for his research into human lactation and founded the UWA Human Lactation Research Group, now led by Associate Professor Donna Geddes.
By understanding exactly how the process of lactation works, researchers such as Assistant Professor Kent are able to provide an evidence base to improve treatment when medical difficulties arise in breastfeeding mothers, encourage more mothers to breastfeed and improve existing technology in hospitals, such as breast pumps.
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Gustafson, E. J. 1996. Expanding the scale of forest management: allocating timber harvests in time and space. Forest Ecology and Management 87:27-39.
Gustafson, E.J. 1998. Clustering timber harvests and the effect of dynamic forest management policy on forest fragmentation. Ecosystems 1:484-492.
Gustafson, E.J. 2001. Simulating changes in landscape pattern. Pages 49-61 in Learning Landscape Ecology: A Practical Guide to Concepts and Techniques, S. Gergel and M.G. Turner, (eds). Springer-Verlag, New York.
Gustafson, E.J. and T. R. Crow. 1999. HARVEST: linking timber harvest strategies to landscape patterns. In Spatial modeling of forest landscapes: approaches and applications, Mladenoff, D.J., Baker, W.L. (Eds.), Cambridge University Press, Cambridge, United Kingdom, pp. 309-332.
Gustafson, E.J. and T.R. Crow. 1994. Modeling the effects of forest harvesting on landscape structure and the spatial distribution of cowbird brood parasitism. Landscape Ecology 9:237-248.
Gustafson, E.J. and T.R. Crow. 1996. Simulating the effects of alternative forest management strategies on landscape structure. Journal of Environmental Management 46:77-94.
Gustafson, E.J. and T.R. Crow. 1998. Simulating spatial and temporal context of forest management using hypothetical landscapes. Environmental Management 22:777-787.
Gustafson, E.J. and L.V. Rasmussen. 2002. Assessing the spatial implications of interactions among strategic forest management options using a Windows-based harvest simulator. Computers and Electronics in Agriculture 33:179-196.
Gustafson, E. J., L.J. Roberts, and L.A. Leefers. In review. Linking linear programming and spatial simulation models to predict landscape effects of forest management alternatives. Journal of Environmental Management.
Gustafson, E. J., D.E. Lytle, R. Swaty and C. Loehle. In reviewB. Simulating the cumulative effects of the forest management strategies of multiple landowners on landscape pattern and biodiversity.
Gustafson , E. J. and C. Loehle. In prep. Effects on landscape pattern of parcelization and land divestiture in an industrial forest landscape.
Leefers, L.A., L J. Roberts and E.J. Gustafson. 2005. Spatial sensitivity analysis: an application of HARVEST to a Spectrum alternative. In: Bevers, Michael; Barrett, Tara M., comps. Systems Analysis in Forest Resources: Proceedings of the 2003 Symposium; October 7-9, Stevenson, WA. Gen. Tech. Rep. PNW-GTR-000. Portland, OR: U.S. Department of Agriculture Forest Service, Pacific Northwest Research Station.
Mladenoff, D.J. and B. DeZonia. 2004. APACK 2.23 analysis software: User's guide. Published on Internet server http://forestandwildlifeecology.wisc.edu/staticsites/mladenofflab/P...
Ripple, W.J., G.A. Bradshaw, and T.A. Spies. 1991. Measuring landscape pattern in the Cascade Range of Oregon, USA. Biological Conservation 57:73-88.
Zollner, P. A., Gustafson, E. J., He, H. S., Radeloff, V.C., Mladenoff, D. J. 2005. Modeling the Influence of Dynamic Zoning of Forest Harvesting on a Northern Wisconsin Landscape. Environmental Management 35:410-425.
Creation and Review Dates


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Hotfrog NewZealand provides information regarding Specsavers Optometrists in Christchurch Canterbury. Specsavers Optometrists is located at Cashel Street 07, Triangle Centre, Christchurch Canterbury and provides Healthcare services. Contact them on 03-377 1406 or by visiting them on their website http://www.specsavers.co.nz.
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The Braves franchise is one of the oldest in professional baseball, tracing its roots back to 1876. As the Boston Braves, the franchise constructed some excellent teams but won just one World Series in 1914. A move to Milwaukee in 1953 brought newfound success for the franchise. After winning 92 games its first year in Milwaukee, the Braves won their second World Series in 1957 on the back of Hank Aaron and his 44 home runs. Milwaukee returned to the World Series the following season, but lost to the Yankees in seven games. The Braves moved to Atlanta in the mid-1960s, and experienced their greatest success starting in the 1990s, when Bobby Cox was returned to manage the team for a second time. Atlanta reached back-to-back World Series in Cox's first two years back on the job, but failed to take home the title in either. In 1995 the Braves won their third World Series in franchise history, riding a fearsome starting rotation of Greg Maddux, Tom Glavine and Jon Smoltz. Starting that season, the Braves would win 11 straight NL East titles, winning the one World Series and playing in two more. The Braves have retired the numbers of 10 former players and managers. Score with TicketCity - the place to go for Atlanta Braves baseball tickets.
1. Scan through the 2017 Atlanta Braves Schedule and select the game that you would like to attend, or use the opponent or date filters beside the Atlanta Braves ticket listings to find the perfect matchup. 2. Click "Select" to reveal all available Atlanta Braves tickets, the Turner Field interactive seating chart, ticket quantity, and ticket price filters. Use the ticket price filter, and ticket quantity filter to quickly refine your search to the available Atlanta Braves tickets that are in your price range. You can also utilize the "eTickets Only" filter to find all Atlanta Braves tickets that will be delivered electronically. The Turner Field interactive map can be employed to reveal all tickets available for a preferred section. Select the perfect tickets and click "Go" to proceed to checkout. 3. Review the checkout page to ensure that the correct Atlanta Braves tickets have been selected, and read through any ticket notes or delivery information. If everything looks correct, fill out the checkout information, and purchase your Atlanta Braves Tickets!
Our Sales and Service teams are available 7 days a week at 1-800-880-8886.
The Atlanta Braves once again struggled in 2016 and extended their postseason drought to three seasons. The Braves are working on rebuilding the team and developing new talent and are not expected to contend in 2017, as they spent their offseason signing veteran pitchers such as R.A. Dickey, Bartolo Colon, and Jaime Garcia to short contracts while their top pitching prospects develop. The Braves already have several young prospects that are looking to have breakout seasons, including top prospect Dansby Swanson. The 2017 Atlanta Braves season will be the team's first season at the brand new SunTrust Park.
The Braves play their home games at Turner Field, located in Atlanta, Georgia. When filled to capacity, Turner Field holds nearly 50,000 screaming Braves fans. Home to some of the greatest fans in the world, the Atlanta faithful are known for their intimidating tomahawk chops in the direction of the opposition. The Atlanta Braves dugout is on the Turner Field first base line in front of sections 111-117. Turner Field parking information is covered in our Braves event guide.
New York Mets, Chicago Cubs
Though the rivalry between these two NL East clubs goes back to the 1960s, it only really became heated in the last two decades. With realignment in the early 1990s, these two teams became divisional foes for the first time. By the late 1990s it was clear the Mets and Braves were the class of the division and it led to many contentious battles for supremacy. This has been one of the better matchups in the National League, and both teams are always loaded with star talent.
This rivalry is between the two oldest clubs in MLB history. The Braves are first credited with being a major league team all the way back in 1871 and the Cubs came around not too long after in 1874. Both are founding members of the National League and have played over 2000 times since 1901. If you are a fan of history or just love great baseball, this is a rivalry that you don't want to miss.
The Atlanta Braves went on a 15-year run that has not been duplicated in Major League Baseball. Other than the strike-shortened season in 1994, the Braves won their division every year starting in 1991. The historic streak ended in 2005 and was highlighted with five NL pennants and a World Series title in 1995. The organization has also won over 17 division titles and will only continue to add to that number in the upcoming years.
The main gates open 2 and a half hours before the first pitch at Turner Field.
Barbeque fans should not miss out on trying Daddy D'z BBQ Joynt. One of the best barbeque places in Atlanta, Daddy D'z is only about a mile from Turner field and is usually full of Braves fans before games. If you enjoy trying fresh takes on traditional American food, try Fresh To Order. FTO has great sandwiches, and drink selections. The Varsity is a quick and fun place and is often on the list of food critics in the area. No Atlanta food guide is complete without listing some of the great southern food options in the city. Mary Mac's Tea Room and Gladys Knight's Signature Chicken & Waffles are two of the best anywhere. Other good places in the area are Kevin Rathbun Steakhouse, Ria's Bluebird, and The Vortex Bar and Grill.
There are a number of great parking options close to Turner Field. The largest parking lots in the area are located just north of the stadium on the east and west sides of Hank Aaron Drive. There are also some good spots on the west side of Central Avenue just north of Ralph David Abernathy Boulevard. If you don't mind walking there are other parking lots on the north side of Fulton Street just west of 75/85.
Children 2 years old and younger may enter Turner Field without a ticket but must sit on a parents lap for the duration of the game. It is best practice to bring proof of your child's age with you to the game to ensure they are allowed to enter.
The Atlanta Braves missed the postseason for a second straight season a year ago, struggling in one of baseball's toughest divisions. The young Braves may still be a few years away from returning to the top of the NL East, but there is reason to believe that they are moving in the right direction, and plenty of reason to watch this season. The biggest new face in Atlanta's lineup is Ender Inciarte, who comes over after hitting .303 and driving in 45 RBI's a season ago. Inciarte should add some much needed pop to the Atlanta Braves offense, which it was so desperately lacking a year ago. To sure up the Braves 2016 rotation, Atlanta brought in Bud Norris, and Matt Wisler, which should help give the Braves 5 solid options at the top of their rotation. The Atlanta Braves have a fanatic following, and Braves tickets should still be in high demand in 2016. Look for an exciting Atlanta Braves team to make progress in 2016 and move closer to being a contender.
A year after returning to the top of the NL East standings, the Atlanta Braves took a step back in 2014. The Braves finished tied for second in the division, but had a disappointing 79-83 record, which left the club looking for answers coming into the 2015 MLB Season. In the offseason, the Atlanta Braves lost key pitchers Ervin Santana, Aaron Harang, and Brandon Beachy. Despite the roster losses, the 2015 Atlanta Braves will feature a wave of new talent that will try and help the Braves back into the hunt for October. Key additions to the 2015 Atlanta Braves includes veteran leader A.J. Pierzynski, Jonny Gomes, Shelby Miller, Jason Grilli, and Manny Banuelos. Dethroning the defending AL East Champion Washington Nationals will be a tough task for any of the other teams in the division, but the Atlanta Braves looked poised to be one of the most competitive in the division in 2015 and will likely be in the playoff hunt once again.
The Atlanta Braves had a very successful season in 2013, winning 96 games as well as the NL East division championship. This year they're still not the favorites, as many analysts are picking the Washington Nationals to go as far as the World Series. The Braves will use that as motivation going forward, and they're used to being the underdogs. The lineup is strong from top to bottom, and they'll need Evan Gattis to replace at least some of the production of Brian McCann, who hightailed it to the Bronx during free agency. The rotation doesn't seem to have an ace, but it has been assembled with five quality pitchers and they'll have Craig Kimbrel to close games out. The Braves will be above .500 this season, but will they be closer to 85 or 100 wins?
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text:
©2008 BMoore Photography & Design…………………………
awww, there's my lover!!! love you bonita!!! gorgeous work my dear!!! great to see you.
Gorgeous! I sure do miss you……so happy to see you on here today sis. How are you feeling? LOVE YOU BABY!!!!!!!!!
Simple and lovely. Great use of bokeh and lighting. And the focus really is in focus.
hi bonita…you have been missed….. this does speak volumns dear friend….love and hugs always to you………..
Heyyyyyyyyy this is Maple leaves and this are all around my city of Toronto right now in all its beauty with mindblowing shades but this B&W shades indeed speaks a lot..
Woooo Hooooooo!!! Love it, Sis!!!
Very delicate yet powerful! Beautiful job my dear :)
this is lovely it is like something i would see in dreams well done!!
Lovely image!
what a wonderful look here. awesome done in black n white.
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YAP is a high-performance Prolog compiler developed at
LIACC/Universidade do Porto and at COPPE Sistemas/UFRJ. Its Prolog
engine is based in the WAM (Warren Abstract Machine), with several
optimizations for better performance. YAP follows the Edinburgh
tradition, and is largely compatible with the ISO-Prolog standard and
with Quintus and SICStus Prolog.
WWW: http://www.dcc.fc.up.pt/~vsc/Yap/
To install the port: cd /usr/ports/lang/yap/ && make install cleanTo add the package: pkg install yap
cd /usr/ports/lang/yap/ && make install clean
pkg install yap
PKGNAME: yap
ONLY_FOR_ARCHS: nil
NOT_FOR_ARCHS: nil
SHA256 (yap-6.2.2.tar.gz) = f15f8382104443319a5883eafce5f52f4143b526c7f1cd88d19c1f63fc06d750
SIZE (yap-6.2.2.tar.gz) = 5499811
NOTE: FreshPorts displays only information on required and default dependencies. Optional dependencies are not covered.
===> The following configuration options are available for yap-6.2.2_3:
DOCS=on: Build and/or install documentation
===> Use 'make config' to modify these settings
gmake localbase readline
Number of commits found: 45
lang/yap{,-devel}: use clang and unbreak with gcc5 or later
In file included from ./Solver.C:20:
In file included from ./Solver.h:29:
./SolverTypes.h:122:20: error: friend declaration specifying a default argument
must be a definition
friend Clause* Clause_new(const V& ps, bool learnt = false);
./SolverTypes.h:147:9: error: friend declaration specifying a default argument
must be the only
Clause* Clause_new(const V& ps, bool learnt) {
./SolverTypes.h:122:20: note: previous declaration is here
friend Clause* Clause_new(const V& ps, bool learnt = false);
./Solver.C:123:21: error: no matching function for call to 'Clause_new'
Clause* c = Clause_new(ps, false);
./Solver.C:602:29: error: no matching function for call to 'Clause_new'
Clause* c = Clause_new(learnt_clause, true);
4 errors generated.
Obtained from: upstream
Approved by: portmgr blanket
Bump PORTREVISIONS for ports depending on the canonical version of GCC and
lang/gcc which have moved from GCC 4.8.5 to GCC 4.9.4 (at least under some
circumstances such as versions of FreeBSD or platforms).
In particular that is ports with USE_GCC=yes, USE_GCC=any, or one of
gcc-c++11-lib, openmp, nestedfct, c++11-lib as well as c++14-lang,
c++11-lang, c++0x, c11 requested via USES=compiler.
Remove ${PORTSDIR}/ from dependencies, categories h, i, j, k, and l.
With hat: portmgr
Sponsored by: Absolight
- Fix docs build after texlive upgrade
- Fix build without docs
Cleanup plist
Fix build by removing texlive from USE_TEX.
While here, just add install_docs to INSTALL_TARGET rather than
calling a separate ${MAKE} without MAKE_ENV or MAKE_ARGS.
- Use texlive as build depends instead of tetex
- Build with GCC
- Remove extra patches
- Fix build with clang on i386
- Change maintainer email to @FreeBSD.org
- Add stage support
- Convert USE_GMAKE to USES
Approved by: wg (mentor)
Add NO_STAGE all over the place in preparation for the staging support (cat:
- Fix plist
- Insert PORTSCOUT
PR: ports/180264
Submitted by: Danilo Egea Gondolfo <email@example.com> (maintainer)
- Remove MAKE_JOBS_SAFE variable
Approved by: portmgr (bdrewery)
YAP is a high-performance Prolog compiler developed at
LIACC/Universidade do Porto and at COPPE Sistemas/UFRJ. Its Prolog
engine is based in the WAM (Warren Abstract Machine), with several
optimizations for better performance. YAP follows the Edinburgh
tradition, and is largely compatible with the ISO-Prolog standard and
with Quintus and SICStus Prolog.
WWW: http://www.dcc.fc.up.pt/~vsc/Yap/
PR: ports/180068
Submitted by: Danilo Egea Gondolfo <firstname.lastname@example.com>
2006-12-01 misc/instant-workstation: Incomplete pkg-plist
2006-12-01 lang/yap: Does not compile
2006-12-01 lang/tensile: "Coredump during build on FreeBSD >= 6.x"
Schedule these broken ports for termination on 2006-12-01
BROKEN: Does not compile
fix build on releng_4
upgrade to 5.1.1
Chase gmp library and bump PORTREVISION.
Remove USE_REINPLACE from the categories starting with L
- Update to 5.0.1
PR: ports/92011
Submitted by: Ports Fury
- Add SHA256
- Builds and runs on !i386
Tested by: Johan van Selst <firstname.lastname@example.com> (amd64),
barner (sparc64, ia64)
Submitted by: Johan van Selst <firstname.lastname@example.com>
PR: ports/86081
Update to 5.0.0
PR: ports/85881
Submitted by: Ports Fury
- Fix SIZE on distinfo
Approved by: flz (mentor)
- Update to 4.5.6
PR: ports/83715
Submitted by: David Gullasch <email@example.com>
Approved by: flz (mentor)
At Kris's request, back out the MACHINE_ARCH spelling correction until
after 5.4-RELEASE.
Assist getting more ports working on AMD64 by obeying the
Ports Collection documentation and use 'ARCH' rather than 'MACHINE_ARCH'.
- Update to 4.5.5
PR: ports/79750
Submitted by: Ports Fury
BROKEN on !i386: Does not compile
Update to version 4.5.2
PR: ports/71299
Submitted by: Ports Fury
Info files cannot be installed in post-install
BROKEN on alpha: Does not compile
- Update to version 4.4.4
PR: ports/63008
Submitted by: Ports Fury
- Update to version 4.4.3
Submitted by: Ports Fury
Sweep through and fix some dependency problems and forgotten shlib
version bumps
Noticed by: bento
upgrade to 4.3.22
upgrade to 4.3.21
Update to 4.3.20
Submitted by: email@example.com
Use GNU_CONFIGURE and some style changes
upgrade to 4.3.19 drop maintainership
add yap A high-performance Prolog compiler
Servers and bandwidth provided byNew York Internet, SuperNews, and RootBSD
12 vulnerabilities affecting 25 ports have been reported in the past 14 days
* - modified, not new
All vulnerabilities


text:
Is Newmarket Solutions incorrect or missing key business information? Update your Hotfrog listing today.
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Is Newmarket Solutions in 2A Century Business Park St Margarets Rd, Dublin Dublin your business? Claim your listing and attract more leads by adding more content, photos and other business details.
8 Manor Heath Dublin DUBLIN 14
Cope St Dublin
20 Fortlawn Park Dublin DUBLIN 15
35 Thomas Court Thomas St Dublin
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The ACER Pavilion in the London 2012 Olympic Park was a unique interactive experiential pavilion, which allowed visitors to go on an action-packed 'ACER Journey'.
The Journey extended across a three-level pavilion, and was packed with cutting-edge technology, giving visitors a highly unusual inspirational and engaging brand experience.
Groups of eighty to a hundred visitors were ushered into the pavilion every fifteen minutes. These groups were allocated approximately fifteen minutes on both level one and level two of the pavilion.
Level one was dedicated to a Mixed Reality Theatre, which combined 3D refractive images with a real actor on stage, giving visitors a show like no other. The state of the art CGI video centred around 'Acerman', the brand's superhero, who burst out of the screen in a flash of light, bringing technology to life!
On the second level visitors entered an interactive gaming and discovery area, including the Challenge Arena, the Journey Sphere, an Infinity Room and several device bars. Using their QR cards visitors could race against each other and play mind games, all using their very own personalised avatar.
Level three, which offered a breath-taking view of the park, was limited to ACER corporate guests, including athletes and press. It was a multi-functional space, suitable for meetings, networking and relaxing in a tranquil and stylish setting.
ACER wanted to create an experience with a strong brand attractor to enhance their public image and raise awareness of the brand's unique qualities.
Engaging the public was key to ACER's vision for the pavilion. They wanted the visitor experience to be fully interactive, utilising cutting-edge technology to express the brand's leading position in the technology market and supporting ACER's aim of enacting a perception change in the public domain.
ACER stipulated the theme of 'a journey' for the pavilion experience; a theme which aligned with their wider marketing activities. Pico interpreted this theme through the creation of a series of interactive experiences and a visual narrative.
ACER asked for a three level pavilion, with the third level specifically designed for corporate hospitality.
The ACER Pavilion's final footprint was a 400 sq.m. rectangle, eight meters in height, with an open frontage. Because of the shape and remote position of the footprint, the initial vision for the pavilion had to be re-imagined. With only the front facing the Park, the vision of a circular building with 360-degree moving facade was replaced by a design for a rectangular building, with forward-facing moving facade. The highly visible LED screen could be seen at a great distance, and was designed to act as a powerful visitor attractor to compensate for the poor projected footfall of the out-of-the-way location.
The visitor experience began with the visual attractor of the exterior, which featured a moving facade, an effect created by shutters moving in sequence and a 120 sq.m. LED screen.
Upon joining the queue they were engaged by ACER "Brand Ambassadors" and their details registered using ACER tablets, introducing them to ACER's technology. A photo of their face was also taken using the tablets, known as a "face-grab", and the image then transplanted onto a personalised avatar. They were then given a QR card with their details stored on the card.
The experience inside the Pavilion began with a Mixed-Reality Theatre show on the first floor, featuring a combination of a refractive video and a live actor playing the part of "Acerman" ACER's very own superhero.
On level two visitors were greeted by a huge range of technology-based activities, all aimed at showcasing ACER's products in a fun and engaging way. These included the QR Challenge Arena, the QR Journey Sphere, the QR Infinity Room and the Predator Gaming Area. There were also several Device Bars for visitors to try out featured ACER products.
After completing their on-site experience, visitors were given the opportunity to continue their 'ACER Journey' with their personalised avatar via a linked website.
Designed to draw in the crowds, the facade of the Pavilion featured thirty moving shutters which worked in sync with a 120 sq. m 10P LED screen. The shutters were unique and created especially for ACER by Pico. The design was inspired by the laptop computers' opening and closing movement, to put visitors in a 'computer technology mindset' before they even entered the Pavilion. The shutters were programmed to draw back in sequence to reveal a marketing video for ACER on the theme of "Exploration, Discovery and Knowledge". The moving facade of the ACER Pavilion was the only one of its kind in the Olympic Park, and received much praise in the general press as well as in specific relevant market publications.
The "ACER Journey" began outside the Pavilion where "Brand Ambassadors" registered each person in the queue using ACER tablets.
A photo of their face was then taken, a process known as a 'face grab', and their image transplanted onto a personalised avatar, a character who was then their digital representation. Their details and avatar were then stored on a QR card, introducing a fully interactive QR capture-supporting technology that ran through the showcase experience. Pico created 150,000 unique QR codes; one for each visitor who took part in the experience.
Upon entering the Pavilion, visitors were first directed to the Mixed-Reality Theatre. The theatre featured a high-definition 3D refractive video projection; technology which allows a moving three-dimensional video to be played on a stage. The video was an entertaining, brand-promoting, visual experience, created using state of the art CGI, which introduced visitors to ACER's philosophy of enabling their customers to go on a journey of 'Discovery, Exploration, and Knowledge'.
The central figure in the video was 'Acerman', the brand's superhero, who was part life-sized hologram and part actor; causing viewers to be unsure where technology ended, and reality began. This element added a touch of magic to the performance, particularly at the end when he appeared to burst out of the video in a flash of light, bringing the technology to life!
The 'Challenge Arena' was a virtual racing board which used state of the art programming and 3D projection mapping technology, allowing three-dimensional points to be mapped onto a two-dimensional plane. Eight players at a time gathered around the large oval-shaped table, each at their own tablet station. They then placed their QR card into a card reader next to the tablet, which made their personal avatar visible on the tablet screen and the virtual playing board. The players then raced their avatars against each other whilst fighting through different obstacles on the projection. By coming in the top three in this popular game, visitors won points which they could then use to enter a competition to win ACER products.
The Journey Sphere utilised unique Pico technology, based on a spectacular 360-degree spherical display system. It combined and connected the spherical display system to ACER tablets making it fully interactive and highly engaging.
The sphere glowed ACER green, attracting visitors with its unusual shape and moving interactive content. When visitors placed their personal QR cards in one of the ten tablets surrounding the Journey Sphere, their avatar name and picture immediately appeared on the sphere itself and enabled the tracking pad on the ACER tablet. This directly corresponded with the spheres' content, allowing players to move the cursor and click on different highlighted sections of the sphere, each of which represented individual games. The games included five fiendishly fun challenges, especially created for ACER's Olympic Pavilion: On Target, On the Dot, Puzzling, Sync or Swim, and Thanks for the Memories.
The Infinity Room, so-called because of the infinity mirrors that wrapped the room reflecting a million images of the visitor back at them, gave visitors the chance to capture an image of themselves at the ACER Pavilion. Each visitor entered the Infinity Room alone, and music played while photos were taken of the visitor in different poses. These could be accessed on the ACER website after the visitor had left the ACER Pavilion experience.
Device Bars were located on the first and second floors, where visitors could use ACER computers and tablets to play games and access unique ACER content.
From the Device Bars visitors were able to access five fiendishly fun challenges, especially created for ACER's Olympic Pavilion: On Target, On the Dot, Puzzling, Sync or Swim, and Thanks for the Memories.
On Target - visitors were able to try their hand at shooting a bulls eye with a virtual bow and arrow.
On the Dot - visitors' reaction times were challenged as they had to hit highlighted dots. Speed was of the essence!
Puzzling - a sliding tile puzzle game where visitors were challenged to correctly assemble an image of an Olympic athlete in motion, against the clock.
Sync or Swim - a rowing game in which visitors had to match the rhythm of the stroke to travel further. The higher the accuracy the faster their time!
Thanks for the Memories - visitors' memories were tested, as players had to memorise patterns and movements and play against the computer to win points.
In the Predator Gaming Area visitors could play London 2012: The Official Video Game of the Olympic Games on ACER's new gaming computers. The Predator combines gamer-savvy graphics, razor-edge processing, and ultra-fast memory technology to enable a powerful gaming experience. Visitors played individually using joystick controllers, and were able to try their hand at virtual archery, swimming, tennis and a whole host of other sports.
Each visitor's personal QR card was the key to their post-event experience. Each visitor's personal avatar, created during their QR sign-up, could be customised by changing the colour of its hair or clothing. This created a more personalised experience for visitors and aided interaction with the ACER brand.
While exploring the games and activities online, visitors could also add to the points they collected at the ACER Pavilion. After collecting 100 points they became eligible to enter a competition to win an ACER tablet via the ACER Journey website. This was a huge incentive for people to continue their interaction with the ACER brand beyond their initial experience at the Pavilion.
Those not collecting the requisite number of points were still encouraged to go on the website to play games and continue their ACER Journey with their customized avatar. They were also given the option of sharing their avatar on social media sites.
The Corporate Hospitality Suite located on level three was a large open-plan space in which athletes, VIPs, press and corporate guests of ACER could relax, watch the Games, and enjoy food and drink in a private and elegant setting.
The Suite was comprised of multiple sections including reception desk, refreshment bar, several meeting rooms, and a TV viewing area. There was also a balcony with covered outdoor seating and a stunning view across the Park , as well as several Device Bars for guests to try out ACER products.
Click here to find out how to activate your brand.


text:
MAT/PACE Program
The Master of Arts in Teaching / Panhandle Alternative Certification for Educators (MAT/PACE) program is an online, university-based teacher certification program for degreed individuals who want to make a career transition into the teaching profession. The program, which ultimately culminates in Texas educator certification and an advanced degree, begins with testing, early field-based experiences, and online graduate course work. An eligible candidate may be employed as a Texas teacher or may complete clinical teaching under the supervision of an experienced teacher. Upon attaining initial teacher certification, individuals may continue with completion of the Master of Arts in Teaching degree.
Detailed program information, including step-by-step admission and application requirements, course work, and cost, is included in the PACE Information/Application Packet. Please allow 3 weeks for evaluation.
Application Deadlines
Summer Enrollment - application timeline and deadlines
Jan 1 - April 1 application deadline
May 1 - application documentation deadline
Fall application timeline and deadlines
May 1 - August 1 application deadline
August 10- application documentation deadline
Spring application timeline and deadlines
September 1 - December 1 application deadline
December 10 - application documentation deadline
WT's educator preparation programs are rated "accredited" by the Texas Education Agency's Accountability System for Educator Preparation: Consumer Information about Educator Preparation Programs.
WTAMU's Title II Institutional Report may be accessed on the U.S. Department of Education website: https://title2.ed.gov.


text:
Channel a classic look with this Truman Bifold from Fossil. This slim wallet is crafted from 100% rich leather, featuring 8 credit card slots, 2 slip pockets and 1 bill compartment.
Thank you for visiting Fossil Truman Bifold, Cordovan on shoppingfind.co.uk
We bring the products from many websites to one website for you to search, save and compare.


text:
Can Someone Really save hundreds on auto insurance? For one to believe thus, insurance companies would undoubtedly like. When an insurance company believes you present a threat that is good, then it'll show you with low auto insurance costs. Otherwise, you're better off remaining with your present business. By
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Be Baby Starlight Dreamshow Yellow
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Be Baby Starlight Dreamshow Yellow Product Description
Product Features: A star-shaped dreamshow that projects magical, dream-time characters, stars and moons onto the ceiling Plays 3 soothing lullabies to gently send baby to sleep Attatches to the cot or free-standing Batteries: 4 x AA required Age: From Birth
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Look Inside | Enlarge Cover
Jun 01, 2006
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Marvel at God's hand on your own life! Record your personal journey in this companion to Bruce Wilkinson's New York Times bestseller, Secrets of the Vine.
Bruce Wilkinson is recognized as one of the world's foremost Christian teachers and speakers. But he is best known as the author of the New York Times #1 bestseller, The Prayer of Jabez, and other bestsellers including A Life God… More about Bruce Wilkinson
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Jay Hieron Talks Strikeforce, UFC And Titles watch video >>
Joe Riggs Talks Nick Diaz, Jay Hieron & Strikeforce watch video >>
Herschel Walker Talks Fighting For Charity In Strikeforce watch video >>
Marloes Coenen Strikeforce Locker Room Interview watch video >>
Strikeforce Miami Promo watch video >>
MMA Confidential All-Access At Strikeforce Evolution watch video >>
Strikeforce Rising Star Marloes Coenen will face Cris "Cyborg" Santos @ Strikeforce Miami. watch video >>
Strikeforce's first card of 2010 features Nick Diaz, Robbie Lawler, Cris Cyborg, Melvin Manhoef, and Herschel Walker to name a few. watch video >>
Jay Hieron Focused On Joe Riggs watch video >>
Gegard Mousasi wants to run with the best.Strikeforce's light heavyweight champion will join UFC welterweight champion Georges St. Pierre's training camp this week to assist in the French watch video >>


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User State Migration Tool Scenarios
Before taking a look at the two scenarios, Refresh Computer and Replace Computer, the speakers will review the different types of migration stores available. They will look at the migration xml files and show how they can do some simple customizations.
Provided by: Microsoft Topic: Software Date Added: Apr 2011 Format: Podcast


text: Whether your gift recipient dives on a regular basis or took up the hobby on a recent vacation, she'll love the female brown hair scuba personalized Christmas ornament with authentic styling and details. It becomes a custom keepsake she'll enjoy displaying when one of our lettering artists adds the information you provide. It will be hand painted where shown, but in a pretty and stylish font. We offer a matching male scuba diver ornament too, and both arrive ready to display in our plush velvet gift and storage bag. Celebrate spending memorable time beneath the surface with the female brunette scuba diver personalized Christmas ornament from Russell Rhodes.


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Gunung Guesthouse
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... heavens opened not long after. Luckily our taxi driver was outside otherwise it could've been a similar experience to KL.� Starving we asked the driver to take us to a restaurant nearby. Well, this was a slight mission in itself, as it appears most places shut down for a few hours mid afternoon. We were left with little choice but ask our driver who spoke very little English to take us to KFC. Well I guess we did try to have authentic food...� Well dear ...
Miasto kontrastów
... zliczyć. Jestem piękna, mądra i bogata :) :) :) Szkoda, że wcześniej o tym nie wiedziałam, zwłaszcza jeśli chodzi o ostatnią część zdania, czyli bogactwo. Dziś też zrobiono mi ok 20 zdjeć, bo "you're so beautiful". Czułam się jak atrakcja turystyczna- flashe z każdej strony. Tak wiec jeśli masz kompleksy- jeden dzień w Indonezji Cię z nich ...
Jostling around Jakarta
... museum described the change brought about by historical trade and banking with a special focus on the banks creation and position in modern markets. Ian made a new friend in a local school boy called Kevin who struck up a conversation to practice his English with a parting comment echoing down the hall "see you in the UK Ian".
Navigating our way around the city streets, we took our lives into our own hands crossing the busy roads; green man doesn't mean cross ...
3rd to 5th October
... dress code wrong and made a bee-line for the incredible ice sculpture dominating the room, flanked by what looked like German secret service men.... Fitting suitably into my tourist role I began taking pictures, obligatory mock peace sign was absent however... I was not keen on insulting any of the many Chinese and Japanese delegates who were present.... Having felt in reality like a total fish out of water all night, the evening ended with a wonderful photo booth moment in front of ...
The sun never shines in Jakarta
We weighed our options to come to Jakarta. We were going to continue south but the prospect of so many long hours in a Sumatran bus wasn't appealing. There was one more sight I had wished to see here but there was also a compromise to make so we took a flight to Jakarta. We found a cheap ticket online but could not book it due to the airline policy of not accepting credit card payment for flights leaving less that 48hours from the time of purchase. So we took a gamble and ...


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1. In the food processor, place the strawberries, lemon juice, grand marnier and maple syrup.
2. Process at high speed, until the ingredients are smooth for about 2-3 minutes; do not forget to scrape the sides.
3. Once done transfer it in a bowl, cover and refrigerate for about 2 hours to overnight.
4. After 2 hours pour the chilled strawberry base in the ice cream maker and churn for 20-25 minutes or until you get an ice cream consistency.
5. Serve the strawberry sorbet with a garnish of fresh mint.
Once you finish churning transfer the sorbet in a container and keep it in the refrigerator if not using immediately.
Serving size Per servingComplete recipe
Calories 308 Calories from Fat 7
% Daily Value*
Total Fat 0.82 g1.3%
Saturated Fat 0.06 g0.3%
Trans Fat 0 g
Cholesterol 0 mg
Sodium 8.7 mg0.4%
Total Carbohydrates 69 g23.1%
Dietary Fiber 4.6 g18.3%
Sugars 52.9 g
Protein 2 g3.1%
Vitamin A 0.8%
Vitamin C 226.3%
Calcium 8.4%
Iron 9.9%
*Based on a 2000 Calorie diet


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No Artificial Flavor, No Milk, No Lactose, No Soy, No Gluten, No Wheat, No Yeast, No Fish. Sodium Free
Supplement Facts:
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Sex Differences in Mathematical Reasoning Ability: More Facts
Camilla Persson Benbow and Julian C. Stanley
New Series, Vol. 222, No. 4627 (Dec. 2, 1983), pp. 1029-1031
Published by: American Association for the Advancement of Science
Stable URL: http://www.jstor.org/stable/1691289
Page Count: 3
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Almost 40,000 selected seventh-grade students from the Middle Atlantic region of the United States took the College Board Scholastic Aptitude Test as part of the Johns Hopkins regional talent search in 1980, 1981, and 1982. A separate nationwide talent search was conducted in which any student under age 13 who was willing to take the test was eligible. The results obtained by both procedures establish that by age 13 a large sex difference in mathematical reasoning ability exists and that it is especially pronounced at the high end of the distribution: among students who scored $\geq $ 700, boys outnumbered girls 13 to 1. Some hypothesized explanations of such differences were not supported by the data.
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Science © 1983 American Association for the Advancement of Science


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Actress Priyanka Chopra, whose debut single In My City has received a lot of compliments, was initially approached by music composer Anu Malik to sing the track Babli Badmaash from the film Shootout At Wadala. Priyanka went on to perform for this song instead. Anu Malik was recently quoted saying that he wanted Priyanka to sing the item number. He added that she is very bubbly and energetic and that he loves the texture of her voice.
Anu also said that Priyanka refused, as she is under a contract with her record label. He said that it is unfortunate and that in the future, he would definitely like to have her sing for his compositions.
Sanjay Gupta-directed Shootout At Wadala, starring John Abraham, Anil Kapoor, Manoj Bajpayee, Kangna Ranaut and Tusshar Kapoor, is set to release on May 1, 2013.


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I'm loving the Table-Time Look & Learn "Mostly Math" learning tablecloth! Can you imagine sitting at this educational tablecloth? Your kids, ages 18 mos. to 6 years, will discover 20 fun, interactive math concepts. Table Time Learning Tablecloth for PreK - K Here's the whole picture of what's on the tablecloth . . . Look how many concepts! Sit here and you'll get to practice your … [Read more...]
40+ Coding Classes, Websites, Games, and Apps for Kids
If you're looking for coding or pre-coding classes, games, toys, and apps, for your kids to learn to code, you'll find everything you need here. But first, let's define terms. Coding is learning a foreign language -- a machine foreign language. Just like any language, the ability to read and write it is a literacy of it's own. The biggest benefit of learning to code is that kids develop … [Read more...]
Talking to Kids About Sex
I just sat down and watched a sex video with my 13-year-old. Well, a sex education video -- that was pretty detailed with anatomical models. FUN TIMES! In this day when kids are exposed to so much, so young, I want my kids to be educated and prepared. Hopefully. Knowledge is power. Talking to Kids About Sex Long before we watched the video, we started going through the book 30 Days of Sex … [Read more...]
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Favorite Cookbooks My Kids Actually Use
About 5:30 in the evening I start imagining a fairy god-cook who whisks in and whips up a healthy meal. Since that's NOT happening, I figured I better keep working on my kid's cooking skills. Thus, I must find cookbooks my kids will actually like and use. They already pack their own lunches and can make breakfast, pasta, frozen pizza, and hot dogs. But their idea of cooking a main … [Read more...]
Geology for Kids
Melissa Weisner's son wanted a geology birthday party. So, like the smart entrepreneurial mom she is, she invented Rock On! A Geology Game & Rock Collection. And we're glad she did -- it's a fun, easy way to teach geology for kids! My kids LOVE it -- we play it often all together as a family. So, not only is it a learning game, it's a great family game! Geology for Kids Now updated … [Read more...]
Harry Potter Potions Class Experiments
If you have a Harry Potter enthusiast in your house, you'll want to try your own Harry Potter Potions Class and Experiments, either for a birthday party or just for fun. I'm thrilled to be joining Rae Gun's annual Harry Potter blog hop. Go here to see all the posts about Harry Potter from bloggers around the web. SCROLL DOWN FOR AN AMAZING HARRY POTTER GIVEAWAY!! Harry Potter Potions Class … [Read more...]
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UMIGO Free Math Website
UMiGO, short for "You Make It Go," is a free math website for first and second graders, kids ages 6 and 7. It's an inventive combination of video stories with games embedded within the narrative. UMiGO calls this "appisodes." The website provides lessons and practice in problem solving and early math skills such as: measurement, addition, skip counting, 2D shapes,and greater than / less than -- … [Read more...]
Review of Osmo Gaming System for iPad
Of all the Osmo Gaming System game apps, we loved Words best of all. (Go figure. I'm a writer, what can I say.) Osmo sees something physically on your table and instantaneously recognizes it on the screen. Choose from four apps about math, words, drawing, and invention. It's amazingly innovative and like that it provides the interactive experience parents want with technology. Review of … [Read more...]
ALEKS Math Website for Kids
Parents, you can avoid any summer slide and even help your kids get ahead in math with ALEKS, a web-based, artificially intelligent mathematics assessment and learning system from McGraw Hill Education correlated to NCTM standards. It's an innovative, award-winning math website for kids third grade and up that will keep them actively learning all summer long. ALEKS Math Website for Kids The math … [Read more...]
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Learning apps for kids are a solid choice for summer learning options. Researchers say that the best educational apps are: ACTIVE ENGAGING --not overly distracting MEANINGFUL to a child's life SOCIAL to include parents and peers Do you agree? Here's a list of new apps your kids might enjoy this summer . . . Spring 2015 Learning Apps for Kids The Counting Kingdom $2.99 Add the … [Read more...]


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dead yj please help ive done everything!!!!
:banghead::banghead::banghead::banghead: 92 yj renegade 4.0 ltr v6
changed cps, changed cam sensor, ignition coil, plugs, made sure its on time, i have fuel at the rail with alot of pressure and spark( kinda wierd though it will spark-spark then sparkspark like double it weird. anyway i have no start it wont even try and i have got a diff computer but it still wouldnt fire. Im at witts end im about to get rid of it cuz i need a second car please help anyone.
did you clock the distributor properley. sounds like it is a tooth off
its cause you have a 4.0 liter v6. the jeep engine is an I6.
are your spark plug wires on properly? not opposite? maybe you are sparking but when the engine is on the second stroke that is clearing the exhaust out of the chamber?
i tried uploading pics of the rotor and stuff but it wouldnt, i put flywheel on 2nd tooth from bottom and rotor at about 4 oclock right on the number one.
the timing marks need to be at top dead center on the compreshion stroke. i think the dist needs to be at 5 oclock
so it wont even try to start if its a tooth off
nope mine was a tooth off did the exact same thing. had fuel, fire, no start
really this sucks, is there any pics or videos that can help me dude im really dieing here my wife has a job lined up for next mon and we nned that jeep to start.
the haynes manuel, or google this is what i found.holding the centerline of the base slot in the 1 o'clock position Distributor Pre-position - All Engines Continue to engage the distributor into the engine. The rotor and distributor will rotate clockwise during installation. This is due to the helical cut gears on the distributor and camshaft. When the distributor is fully seated to the engine block, the centerline of the base slot should be aligned to the clamp bolt mounting hole on the engine Distributor Engaged Position - 4.0L 6-Cylinder Engine The rotor should also be pointed at the 5 o'clock position.
It may be necessary to rotate the rotor and distributor shaft (very slightly) to engage the distributor shaft with the slot in the oil pump gear. The same may have to be done to engage the distributor gear with the camshaft gear.
The distributor is correctly installed when:
ok i was holding it in the 11 oclock position and the rotor around the 5oclock position but i might be off it jus doesnt make sense that it wont fire at all. thanks for the advice could my problem be anything else?
not that i can think of did you remove the dist or did it just stop running?
it just stopped one morning i my driveway
did you check the roter ive seen them woller out
ya i thought about that but i had spark so i wasnt worried i think i might still be off time like u said now should i be just ahaead or just behind or right on the number one post.
just a smig ahead
ok ill try that its gotta be it idk what else it can be is so irritating.
it was prob the cam sensor and the timing just got fuged ive done it my jeep sat in the back yard for almost a year i was so fed up with it
im hoping i didnt put the cam sensor in wrong but it had a ratainer screw so it can only go one of teo ways is there any pics of that i havent found any of those.
and where on the flywheel do i need to have the knoch at i have it on the 2nd to last knoch on the right if your looking at the motor.
i need a pic of a cam ensor inside a dist to know if i did it right or if it matters really it can only go one of two ways but it might matter idk
i will try 2 get a pic tomorrow
That would be awsome thanks
2 Attachment(s)
I hope these help not very good pics
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Yiannis Apartments
Heraklis, Psalidi, Kos 85300, Greece
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This 2 star hotel is located within the city of Kefalonia. All 54 rooms are equipped with air conditioning.
Heraklis Psalidi, Kos 85300, Greece


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Studio classes
Enjoy a wide range of group workout classes
A range of classes and sessions in the studio to help keep your workout programme varied.
Here are some of our current sessions, but do check out our timetable for the full list of workout classes.
Body Pump
The original barbell class that strengthens your entire body. This 60-minute workout challenges all your major muscle groups by using the best weight-room exercises like squats, presses, lifts and curls. Great music, awesome instructors and your choice of weight inspire you to get the results you came for – and fast!
Body Balance
This Yoga, Tai Chi, Pilates workout builds flexibility and strength and leaves you feeling centred and calm.


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Product Information
Officially Licensed Chicago Cubs Dog Jersey! This new style v-neck jersey is made of a micro-mesh polyester and touch fastener closure with button trim. Contrast color trim at neck and sleeves. Looks just like what the pros wear! Dress your pet in game day gear and support your favorite team!
Important Sizing Note: The following measurements are the dimensions of the actual product, not of the pet they fit. After measuring your pet, make sure all measurements fit within the following dimensions (with a little room to spare in the chest and neck).Small
It is a nice shirt, but the size ran bigger than I expected so it doesn't really fit.
Maui loves that grandma sent her this Jersey. Maui is a big Cubs fan and loves that she can wear her cubs jersey to cheer on the Cubs. The jersey has a nice fit and could be worn all year long.
Maui looks great and is ready to cheer on the Cubbies! Got it just in time for spring training and will be wearing it all summer long. Hoping it will bring the Cubs good luck- Love the feel and materials used in this nice jersey!


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Fullhouse Communications
Interior Design, Furniture & Furnishing Products & Services, Home Furnishing
Date:20/12/2014 - 28/12/2014 12:00PM-10:00PM
Admission: Public - Free Admission
Venue: Singapore Expo Hall 4
Save on your X'mas shopping with the grandest year-end home furniture, furnishing and renovation show – Home Planner! Look out for the latest designs in furniture and new interior trends to realize your dream home for the new year. Brought to you by Full House Communications, organizer of top brand Singapore home shows including March Home, The BIG Furniture Fair and My Home International Grand Furniture and Renovation Expo. This festive fair promises to be a grand event with the widest range of the best furniture products and furnishing services with many exciting programmes, cash prizes, attractive gifts and bargains for visitors!
Telephone: +65 6842 7266
Fax: +65 6842 7133
Email: [email protected]
Print this page
Largest scale furniture fair in Singapore! More than 50 booths. Only in Home Planner 2015
Wedding Parade @ Suntec Convention Centre Level 3 Concourse, 8 – 11 August 2013 is the hottest bridal fair with
The BIG Furniture Fair is the show worth waiting for! Lots of furniture and furnishing products will be going on sale at incredible prices! It's the one stop shop for all your home needs with beautiful furniture for every room, many innovative designs and gorgeous interior décor! You'll also receive attractive free gifts when you shop! Don't miss this hottest furniture sale!
Venue: Singapore Expo Hall 7
Opening Hours: 12noon - 10pm
FREE Admission!
Organized by: Full House Communication
Luxury Living 2012 — Singapore's premier home fair for high-end living is coming to town again! Come and discover ways to revamp and create your dream home! Paying special attention to interior design and furniture, you can see how interior designers transform spaces into luxuri
Highlight - Free admission! Door gifts will be given away to those who register online too! Please log on
Summer Romance 22 to 24 April 2011 Suntec Convention & Exhibition Centre, Level 3 12 pm – 10 pm Free Admission Organized by Fullhouse Communications Pte Ltd
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President Donald Trump's first address to the joint session of Congress Tuesday touched on immigration, the economy, foreign policy, health care and unity. Watch the highlights in three minutes. Photo: Getty
The Night They Locked Up All the Smartphones2/28/2017 1:18PM
French Cop Accidentally Shoots Gun During Hollande Speech2/28/2017 11:16PM
Two Women Charged With the Murder of Kim Jong Nam2/28/2017 11:24AM
Listing of the Day: Vegas Three Elevators2/23/2017 3:01PM
Trump Says 'Immigration Reform' Possible2/28/2017 10:58PM
President Trump said "immigration reform is possible" and proposed adopting a merit-based system of legal immigration during an address to a joint session of Congress on Tuesday. Photo: Getty
'Trump Bump' Reaches the Superluxury Car Market2/28/2017 1:23PM
SpaceX Plans to Take Tourists Around the Moon in Two Years2/28/2017 3:48AM
Small Plane Crashes Into Two California Homes2/28/2017 1:28AM
What to Watch For in Trump's Speech to Congress2/28/2017 6:00AM
Am I Doing What I Love?9/22/2016 11:59PM
Golf's Data Revolution9/9/2016 2:16PM
Green Park's Fresh approach to executive searching3/18/2016 11:42AM
The New What's News App8/27/2015 6:03PM
'Logan' Star Hugh Jackman on the Next Wolverine2/28/2017 5:00AM
"Logan" star Hugh Jackman on who could play his Wolverine character after him and what situations might tempt him into considering the role in the future. Photo: 20th Century Fox
CIO Network: Will AI Take Your Job?2/27/2017 11:39PM
CIO Network: Better Speech Recognition Coming Soon2/27/2017 11:46PM
'Logan' Star Hugh Jackman on 'The Greatest Showman'2/28/2017 5:00AM
YouTube's Viewership Could Soon Overtake TV2/27/2017 6:08PM
CIO Network: James Woolsey on Trump's Attitude Toward Intelligence2/28/2017 8:03PM
Former CIA Director James Woolsey comments on the public statements President Trump has made about the intelligence community. He speaks with WSJ's Gerald Seib at the CIO Network in San Francisco.
CIO Network: Securing the Cloud2/28/2017 7:51PM
CIO Network: IoT Devices Vulnerable to Cyberattacks2/28/2017 7:49PM
CIO Network: The Dangers of an Electromagnetic Pulse2/28/2017 7:47PM
CIO Network: The Biggest Cyberthreats Facing the U.S.2/28/2017 7:45PM
Snap IPO: Five Things Critics Are Saying2/28/2017 7:07PM
Snap, the company behind the Snapchat disappearing messaging app, has been facing some criticism ahead of its upcoming initial public offering. WSJ's Lee Hawkins walks through five of the biggest criticisms of the IPO. Photo: Bloomberg News