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legal mumbo jumbo
1. you agree to these terms by using this site
your access to, and use of, www.vitaminwatercanada.ca , including the content, services, and software provided there (collectively, the "site") are subject to the following terms of use and all applicable laws and regulations. if you do not agree and accept, without limitation or qualification, these terms of use, please exit the site.
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please note that other site visitors may post messages or make statements in the services that are inaccurate, misleading, deceptive, or offensive. glacéau and the affiliated entities neither endorse nor are responsible for any opinion, advice, information or statements made in any services by third parties. without limitation, glacéau and the affiliated entities are not responsible for any information or materials made available through the services (including without limitation errors or omissions in postings or links or images embedded in messages or profiles) or results obtained by using any such information or materials. under no circumstances will glacéau, the affiliated entities, or their respective employees, officers, directors, shareholders, agents, representatives, or affiliates, be liable for any loss or damage caused by your reliance on such information or materials. the opinions expressed in the services reflect solely the opinions of the individuals who submitted such opinions, and may not reflect the opinions of glacéau or any affiliated entity.
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6. privacy Policy
the use of this site is subject to the coca-cola ltd. online privacy policy, which form a part of these terms of use of use.
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the site may contain links to sites owned or operated by parties other than glacéau such links are provided for your convenience only. glacéau does not control, and is not responsible for, the content or privacy policies on, or the security of, such sites. without limiting the foregoing, glacéau specifically disclaims any responsibility if such sites:
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glacéau does not endorse the content, or any products or services available, on such sites. if you establish a link to such sites, you do so at your own risk and without the permission of glacéau.
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13. termination
you agree that glacéau, in its sole discretion, may terminate your access to or use of the site, at any time and for any reason, including without limitation if glacéau believes that you have violated or acted inconsistently with the letter or spirit of these terms of use. upon any such termination, your right to use the site and the services will immediately cease. you agree that any termination of your access to or use of the site may be effected without prior notice, and that glacéau may immediately deactivate or delete your account and password, and all related information and files associated with it, and/or bar any further access to such information or files. you agree that neither glacéau nor any affiliated entity will be liable to you or any third party for any termination of your access to the site or to any such information or files, or will be required to make such information or files available to you after any such termination.
14. revisions to the terms
glacéau may at any time, and without notice, revise these terms of use by updating this posting. you are bound by any such revisions and should therefore periodically visit this page to review the current terms of use. you can determine when these terms of use were last revised by referring to the "last updated" legend at the top of this document.
all content and services made available through the site that were not made available as of the "last updated" date above, shall automatically be deemed to be part of the services when first made available through the site. any software or tools made available through the site that were not made available as of the "last updated" date above, shall automatically be deemed to be software for purposes of this agreement when first made available through the site.
when using any services or software on the site, you agree that you are subject to any additional posted guidelines, rules, terms and conditions applicable to such services or software, which rules, terms and conditions are hereby incorporated by reference into these terms of use.
15. revisions to the site
we reserve the right, at any time and from time to time, temporarily or permanently, in whole or in part, to: modify or discontinue the site, the services, or the software, with or without notice; limit the site's availability to any person, geographic area or jurisdiction we choose; charge fees in connection with the use of the site; modify and/or waive any fees charged in connection with the site; and/or offer opportunities to some or all users of the site. you agree that neither we nor any affiliated entity shall be liable to you or to any third party for any modification, suspension or discontinuance of the site, in whole or in part, or of any service, software, content, feature or product offered through the site. your continued use of the site after such changes will indicate your acceptance of such changes.
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this site is intended for users who reside within canada. we make no representation that materials on this site are appropriate or available for use in any particular location. those who choose to visit and use this site do so on their own initiative and are responsible for compliance with local laws. the terms of use as well as the use of this site, including any order or purchase made through this site shall be governed by the laws of the province of ontario and the laws of canada applicable therein. the united nations convention on contracts for the international sale of goods shall not apply.
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if you believe in good faith that materials available on the site infringe your copyright, you (or your agent) may send glacéau a notice requesting that glacéau remove the material or block access to it. notices and counter-notices should be sent to:
glacéau vitaminwater
attention: privacy officer
335 king street east toronto, on m5a 1l1
1-877 glaceau
20. information or complaints
you may contact us by writing to:
glacéau vitaminwater
attention: privacy officer
335 king street east toronto, on m5a 1l1
or by calling us at 1-877 glaceau
21. void where prohibited
although this site is accessible worldwide, not all services discussed or referenced in this website are available to all persons or in all geographic locations or jurisdictions. we reserve the right to limit the availability of this site and/or the provision of any service to any person, geographic area or jurisdiction we so desire, at any time and in our sole discretion.


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26 Oct 2009
Here is an easy glaze for any sort of cake you would try at home. This glaze recipe I have furnished here is too easy to prepare and will hardly consume any of your time. Give this glaze recipe a try the next time you make a cake!
|Powdered sugar
|4 Cup (64 tbs), sifted
|Ground cinnamon
|1⁄2 Teaspoon
|Vanilla extract
|1 Teaspoon
|1⁄4 Cup (4 tbs) (plus 2 tablespoon)
Combine all ingredients, and beat until smooth.
Recipe Summary
Rate It
Nutrition Rank
Nutrition Facts
Serving size: Complete recipe
Calories 2054 Calories from Fat 17
% Daily Value*
Total Fat 2 g2.9%
Saturated Fat 1.1 g5.3%
Trans Fat 0 g
Cholesterol 5.6 mg1.9%
Sodium 23.3 mg1%
Total Carbohydrates 506 g168.5%
Dietary Fiber 1.3 g5.3%
Sugars 487 g
Protein 2 g3.8%
Vitamin A 1.3% Vitamin C 0.16%
Calcium 8.9% Iron 1.3%
*Based on a 2000 Calorie diet
Glaze Recipe

subset: commoncrawl


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The Lezyne Micro Floor Drive High Pressure pump with gauge is the perfect partner for long day rides or touring adventures. Track pump performance and power combine in this compact form factor bike pump designed to fit easily inside a rucksack, bike bag or pannier.
CNC machining keeps weight low and durability high whilst a stainless steel foot peg provides stability and a floor pump feel while inflating. A rubber hose makes connecting to your valve the work of a moment, whilst a double sided chuck assures compatibility with both Presta and Schrader valves. A vital pressure gauge is a welcome touch to prevent the guessing game of how the tyre 'feels' with a little squeeze. Save your squeezing for your loved one.
31 riders
bought this item
7 riders
want this item
All orders are packed & shipped from our HQ in the UK on the same day you order, if in stock and ordered before 3pm GMT Monday to Friday.
We offer both mail and express ship options courtesy of Royal Mail and DHL respectively. Below you will find a rundown of default delivery costs, but to see your personalised shipping cost, please visit the delivery section of checkout when you have added some items to your bag. Please note that orders of bulky items will attract a surcharge.
|Royal Mail*
|£1 standard, or £3.50 for Tracked 48
|DPD Next Day (Mon-Fri), £5.00
|Up to 10 working days, from $8
|2 day, from $10
|Up to 5 working days, from €5
|Next day, from €8
|Up to 5 working days, from €5
|Next day, from €10
|Up to 10 working days, from $10
|3 day, from $20
|Up to 10 working days, from ¥700
|3 day, from ¥1400
|Up to 14 working days, from $10
|3 day, from £20
Returns are really simple. We include a returns address label inside every package, so if you would like to return something to us, just make sure to send it back up to 60 days after you have received it.


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Making Christmas Decorations with Primary School Kids November 23 2011
Here are a few great ideas that you can do with your primary school classes during the buzz and anticipation that inevitably happens during the build up of breaking up from school for Christmas.
Each Christmas decoration below also includes a list of the suggested items you will need to make them.
Festive Fruit-Inspired Decorations
Oranges are traditional for many during the Christmas season, in appearance as well as practice. By drying out orange slices in the oven, you can make a variety of individual Christmas decorations perfect for the Christmas season.
Slices on their own can be fixed to create door wreaths, hung from doors in a pendant-like fashion, or used to decorate Christmas trees when combined with simple loops made from string or pipe cleaners.
You can even create orange skin spirals using a vegetable peeler, making sure not to cut the piece away from the rest of the orange prematurely - 4 to 5 rotations usually look best. These can then be hung as decorations in their own right using string tried to one end (carefully punch a hole using scissors) or combined in numbers to create decorative hanging mobiles.
You will need 1-2 oranges per a student, craft glue, ribbon or coloured string and scissors. For slicing the orange or cutting spirals it will be necessary to use a sharp knife or instrument and we highly recommend an adult or teacher do this on their behalf.
Glitter Cones
Our natural surroundings are full of great beauty once you know where to look!Endless sources of inspiration will be revealed to you and your kids for creating fun, crafty, Christmas decorations in your classroom this Christmas.
Pine Forests are abundant in many locations and ideal places to collect pine cones for use in creative projects such as this simple Christmas craft. The cones respond to both heat and moisture. Store them in a warm, dry place to cause the cones to arc open into their familiar shape. Your kids can paint them green to turn them into Christmas trees or white for snowmen. Coat them in glue and sprinkle with glitter to make mystical eggs, but first soak them in water to cause them to close again.
If you don't live near any forests, you can look at what's available from your local park or even the school yard. Twigs blown from trees, acorns, or even holy sprigs if you're lucky!
You will need: Pine cones (enough for 1 each), craft glue, paint brushes, paint and beads as desired.
Crafty Snowflakes
During the Christmas season, snowflakes are never really far away! A number of craft stores and general hardware stores will sell pipe cleaners pre-coated in a layer of shimmery tinsel, or your students can create a similar effect yourself with simple glitter and glue. For a more modest snowflake, normal pipe cleaners can be covered in white tissue paper.
Take 1 of the pipe cleaners, and then overlap 2 more pipe cleaners bending them around the center of the axis in order to fix together a star shape with 6 spokes. Take an additional 2 pipe cleaners and cut them down to size into 2 inch strips. Bend these small strips in the middle to form triangle shapes. These can then be glued at intervals along each of the 6 spokes to create a variety of flake like patterns, each one as individual as the students in your classroom!
You will need: pipe cleaners (5-6 per student), scissors, glitter & glue (optional), string and soft craft tissue paper (optional)
Christmas Jar Lanterns
Painted jars make great candle lanterns with some fun and simple customizations. Before starting the craft, ask your students to start collecting clear glass jars and ask them to bring them in to store in your classroom.
You will need to pre-purchase a selection of brightly colored ceramic paints or tinted glass varnishes to use for this craft - take a look around your classroom to take inventory of paint that you already have.
Let your students loose when it comes to painting a particular pattern or using a variety of color, though you might like to suggest Christmas themes. Once your students have painted and created a unique design they are happy with, the jars can be fired off in a regular oven to set the paint.
Once this is done and the jars have been allowed to cool, you can create a cradle and handle so that these Christmas lanterns can be carried round. This will vary depending on the size of the jar, so you may wish to help them with this step. Cut enough wire to create a ring that snugly fits the circumference of the top part of the jar, where the lid grooves are and tie this off, cutting off any excess wire. Taking a second section of wire, bend in the middle sufficiently enough to create a simple handle and fix each end to the ring at opposite ends of the jar by wrapping the wire round.
You will need: 1 or 2 glass jars (per student), ceramic paint, paint brushes and soft coated craft wire.
This article was written on behalf of Christmas Trees and Lights who sell a selection of artificial Christmas trees and Christmas fairy lights.


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Two flown to hospital after accident
WASHINGTON TWP., Pa. - Two people were flown to the hospital after a violent wreck in Northampton County around 3:45 p.m. Thursday.
The accident happened along Factoryville Road in Washington Township.
A male and a female were seriously injured.
This Week's Circulars
Lehigh Valley News
Police searching for missing man in Bethlehem
Bethlehem police are searching for a missing 41-year-old man last seen several days ago.Read More »
- Bethlehem police searching for missing elderly man
- Lafayette College asks for temporary dorms amid rise in applicants
- Local movie experts preview the Oscars
- Lily's Hope Foundation provides "packages of hope" to families with premature babies
- Lehigh Valley opens weekend with 5-3 setback at Springfield
- District 11 Wrestling: AAA and AA quarterfinal recap
Latest From The Newsroom
- Public memorial service planned for Al Boscov
- Strong storms move through the region
- Updated Windy and much cooler today, but seasonable for late February
- Man shot, killed by Reading police after allegedly pointing shotgun at officers
- Police investigating morning shooting in Reading
- Judge: Man charged in deadly stabbing will remain jailed
- Police work to bring back murder suspect who fled state with 6-year-old daughter
- Police searching for missing man in Bethlehem
- Bethlehem police searching for missing elderly man
- Police: Driver owes nearly $13,000 in unpaid tolls, fees


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TomatoMAX Pure High Strength Tomato Extract provides you with powerful and highly absorbent lycopene and antioxidants. It is made using 100% natural, active ingredients. A single capsule gives you the equivalent of 1400mg of tomatoes and 17mg of lycopene. TomatoMAX benefits for you Contains 100% natural ingredients One of the most powerful natural tomato products in the market A single TomatoMAX capsule equals the goodness of 2 kilos of ripe tomatoes Clinically proven to enhance the absorption rate of nutrients into the body Rich in antioxidants
Cheapest price we found
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Michael Clarke Duncan net worth: Michael Clarke Duncan was an American actor famous for his imposing stature and his deep, booming voice, who had a net worth of $18 million. Michael Clarke Duncan attained this net worth through a variety of acting jobs, mostly in the world of film. After moving to Hollywood for a career in acting, Duncan had to work as a bodyguard for celebrities to make ends meet. Some of the celebrities he protected from harm during this period include Will Smith, L.L. Cool J, and The Notorious B.I.G. He worked in small parts on TV and in film up until getting cast in the 1998 Michael Bay disaster movie Armageddon. The friendship he struck up with Bruce Willis on the set led to his being cast in what would become his breakout role: John Coffy in The Green Mile. From there, Duncan continued to work in a variety of high profile movies, including The Whole Nine Yards, The Scorpion King, and Tim Burton's 2001 remake of Planet of the Apes. He also got to play a genuine comic book villain in Daredevil, in which he starred as the evil crime lord The Kingpin. Duncan also has had a thriving career in the field of voice acting – his voice has been heard in a variety of animated TV series, animated films, and commercials. Unfortunately, Michael Clarke Duncan died on September 3, 2012 in Los Angeles, California at the age of 54 after suffering from a heart attack.
Michael Clarke Duncan Net Worth
Michael Clarke Duncan
Date of Birth
Dec 10, 1957 - Sep 3, 2012 (54 years old)
Actor, Bodyguard, Voice Actor, Model
United States of America
6 ft 5 in (1.96 m)
More Actors
All net worths are calculated by applying a proprietary algorithm. The results are then fact checked and confirmed by a team of editors. We scan all publicly available data and resources and work diligently to ensure that our numbers are the most accurate and up to date net worth data you will find anywhere on the internet.


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Digital media are exploding. People are interacting with the media, content producers, and each other. They reach out to the storytellers. They talk to the authors, the camera people, the producers, the actors themselves. They influence plots in fiction-driven media. They discuss with other fans their favorite serialized mystery's latest clues. They even learn what blogs their favorite journalist reads or pays the most attention to.
Most of this was possible before, of course, but technology is opening new doors and supercharging existing passions. The ever-accelerating transition of various analog media to digital media is incredible. It facilitates an unprecedented level of involvement in media that previously offered little or no means to interact. It's novel and exciting to people over 30, but to the younger crowd it's different.
To the younger crowd, interactive is simply the way things are. They expect it and will begin to demand it from everything. Much in the way they don't have the same grasp on cable versus broadcast as their parents, young people don't know media without interactivity.
That simple fact significantly and irrevocably changes the media and marketing ecosystem. It's a massive disruptive force responsible for all the mountains of money shifting around.
Someone once told me interactive TV has been a year away for 20 years. And the promise of convergence has lived a similar buzz-hype-death lifecycle over the last decade or so. It's here again, and this time it's bigger than the marriage of the Web and TV. It's bigger than Web 2.0, but the foundations of the new generation of sites and services are partially fueling the explosive growth on the Internet and in other new media. It's everywhere and in practically everything. It's ubiquitous.
Let's look at a few examples of technologies that are embracing and enabling this new convergence.
- BlueCasting delivers content to a Bluetooth-enabled mobile phone from systems in outdoor boards, retail locations, kiosks, and so on. It can effectively bring interactivity to outdoor media and create a new opt-in opportunity for marketers.
- SMS (define) has a relatively long history of fueling unexpected interactivity. Vibes Media and others have been powering JumboTrons and interactive billboards that respond to text messages.
- The same basic interactivity is also being applied to camera phone promotions. Vibes offers Pix-2-Web and Pix-2-Screen, which feature rapid posting of pictures taken with a camera phone and sent to a particular address. JuiceCaster offers similar functionality and marries it with community, blogging, and social networking.
- Wiffiti provides something similar in that you can send a text message and have it appear on a screen in a public place. But Wiffiti puts a wiki spin on it by allowing others in the area to vote on the messages on the screen by texting "fade" or "grow."
Touchscreens and Kiosks
GestureTek is making "Minority Report"-style computer interfaces a reality. You can control a computer interface by holding your hand in the air and performing certain recognized actions. Imagine the impact this will have on digital outdoor advertising.
Video and TV
- Apply the power of tagging images on a site like Flickr to moving images and sound, and you get Click.TV. The network is enabling video to be social-tagged. Powerful stuff.
- Panache powers just-in-time assembly of video assets and allows hotspotting within the video itself. The technology makes addressability and deep interactivity within video a reality.
- Jumpcut and Eyespot provide easy-to-use interfaces for remixing video. They're the ultimate video mashup tools, creating an even wider audience for user-generated content. You don't even have to shoot your own video anymore. Just tweak what others have done or use assets provided by advertisers, as in the case of the Doritos Super Bowl ad contest currently running on Jumpcut.
- BuddyTV is bringing TV closer to fans by creating virtual communities that interact live during TV broadcasts, often moderated by a session leader who has something to do with the program itself. For example, sessions during "Big Brother" may be led by a former contestant.
These are just a few examples. The growth of innovative companies and technologies that are enabling new ways for people to get involved with media is rapidly gaining momentum. For marketers, it means an entirely new landscape to consider. It's no longer simply about blasting a single message to a huge group of passive consumers. It's about serving an empowered media consumer with relevant marketing content. It's about more meaningfully engaging them and finding new ways to open your campaigns to participation. It's time to free that philosophy from the Internet and apply it to all media.
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According to data gathered for the report,'Communications Infrastructure: The Backbone of Digital,' 88% of IT professionals and 61% of marketers ranked their company's current communication infrastructure as 'cutting-edge' or 'good.'
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President Trump's digital savvy isn't limited to social media. As it turns out, the Trump Organization owns thousands of domain names, possibly even more than 10,000.
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Amy Fisher is very withdrawn so far on 'Celebrity Rehab with Dr. Drew' (Sun., 9PM ET on VH1) and it's not sitting well with former Guns N' Roses drummer Steven Adler. Both are patients, but Adler took serious issue with Fisher in two consecutive therapy sessions.
First, he yelled at her when she compared the rehab facilities to prison, defending their current accommodation as far better. Then, in a later group session, Fisher declined to identify herself as an addict or an alcoholic. Instead she said she was just listening right now and had nothing to contribute.
"Might as well identify yourself as what you are," Adler told her. "Because you wouldn't be here if there was nothing."


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Edinson Cavani shot down reports he's agreed terms with Real Madrid. "Right now my only thought is for Napoli."
Spanish media Sport claimed that the Uruguayan had committed himself to the Merengues [12], who would offer €45m plus players.
"During my career people have linked me with numerous clubs, but until there is a signature nothing is for sure," Cavani told Ovacion Digital.
"Right now my only thought is for Napoli. I want to have a few days off before going on international duty. I want to continue working and improving, as in life one must always keep learning new things."
He became the first Capocannoniere in a Napoli jersey since Diego Armando Maradona in 1987-88 and helped them to reach the Champions League.
"It was such a great feeling to win that title, as it was my dream since I first arrived in Italy. Second place is a good result for Napoli, as we were close to Juventus at the start, but then they started to take off."
Keep up to date with the latest news and action from Spain's Primera Division with Football Espana - from the team behind Football Italia. [13]


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Travel effortlessly and stay organized with the ProStyle™ 15-inch Wheeled Case. This lightweight, water-resistant TSA X-ray Friendly laptop wheeled case fits laptops and MacBooks up to 15.4 inches. A spacious main compartment with dedicated internal pockets keeps electronic devices, accessories and other small necessities separate and organized. A separate padded compartment built with a High Density Foam Protection System stores and protects your laptop or MacBook, ensuring maximum protection on the road. The ProStyle™ 15-inch Wheeled Case is equipped with durable wheels and an ergonomic telescoping handle for easy transport through airports and during your commute, making this TSA approved wheeled case a perfect travel companion. Pair this wheeled case with the Collins Laptop Sleeve for added device protection.
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Millions of platelet transfusions are conducted each year, yet the supply of this blood component is limited, thus patient access to treat disorders is problematic. There are also many diseases where platelet production or function are impaired, resulting in severe consequences and where there are limited clinical options available. To address these current limitations, new modes to generate functional platelets in vitro would provide a major benefit to many patients, as well as provide an approach to permit the systematic investigation of mechanisms involved in functional platelet formation. Our goal in this Project is to build upon our recent successful studies where a novel bioreactor system was engineered to house megakaryocytes (Mks) and to generate functional platelets in vitro. We will exploit this system to address our hypothesis;engineered microenvironments in vitro can be tailored to optimize the formation of functional platelets. To address the needs in the program we will:
(Aim 1) establish a bioreactor-based 3D tissue system to study the mechanisms of Mk development and platelet release, with functional outcomes in terms of functional platelets generated and recovered from the system, and (Aim 2) to use this 3D tissue system to investigate mechanisms of platelet production related to biochemical signalling and environmental components (i.e. matrices, oxygen tension) as well as pathological megakaryopoiesis by including Mks from patients with platelet related diseases. With insight from this system we will be positioned to interrogate the maturation of Mks from both normal vs. diseased sources in order to begin to establish differences in Mk outcomes (adhesion, migration, proplatelet formation, platelet production and function). The outcome for the proposed study would be twofold: (1) a new laboratory model for Mk development, proplatelet formation and platelet release in normal and abnormal (disease) states, and (2) mechanistic insight into these processes. In the long run, building upon this new in vitro tissue system would allow for the more systematic understanding of the processes involved in Mk development, as well as insight into modes to intervene in disease states associated with these cells.
Circulating platelets are highly specialized cells produced by Mks that participate in haemostatic and inflammatory functions. Millions of platelet transfusions are conducted each year but the supply of this blood component is limited. Despite their critical role in many physiological functions, little is known about the molecular mechanisms involved in platelet production from Mks, or about the pathogenesis of platelet disorders. With such widespread impact of these diseases, and the lack of good options for clinical treatments, new insight into the formation of platelets from Mks would have a major impact on patients and healthcare. To address this need, we plan to develop a novel human bone marrow system in vitro that can be used to understand the process of Mk formation and development both in normal and disease scenarios, as well as an innovative procedure to produce fully functional platelets for clinical needs.
|Di Buduo, Christian Andrea; Moccia, Francesco; Battiston, Monica et al. (2014) The importance of calcium in the regulation of megakaryocyte function. Haematologica 99:769-78
|Pallotta, Isabella; Kluge, Jonathan A; Moreau, Jodie et al. (2014) Characteristics of platelet gels combined with silk. Biomaterials 35:3678-87
|Rnjak-Kovacina, Jelena; Wray, Lindsay S; Golinski, Julianne M et al. (2014) Arrayed Hollow Channels in Silk-based Scaffolds Provide Functional Outcomes for Engineering Critically-sized Tissue Constructs. Adv Funct Mater 24:2188-2196
|Malara, Alessandro; Currao, Manuela; Gruppi, Cristian et al. (2014) Megakaryocytes contribute to the bone marrow-matrix environment by expressing fibronectin, type IV collagen, and laminin. Stem Cells 32:926-37
|Abbonante, Vittorio; Gruppi, Cristian; Rubel, Diana et al. (2013) Discoidin domain receptor 1 protein is a novel modulator of megakaryocyte-collagen interactions. J Biol Chem 288:16738-46
|Badalucco, Stefania; Di Buduo, Christian Andrea; Campanelli, Rita et al. (2013) Involvement of TGFýý1 in autocrine regulation of proplatelet formation in healthy subjects and patients with primary myelofibrosis. Haematologica 98:514-7


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Travel Blogs from Abbadia San Salvatore
Day 59 - 75 ....degrees, not our score.....
... late October. Tomorrow, we head to San Gimignano in the heart of Tuscany. Only an hour south of Florence, we will be spending the next week there as a base to explore the region and its bounty. Weather is predicted to be sunny and low 70s, we are truly blessed.
While Halloween is not celebrated here, for all those following us in the USA, Happy Halloween!
Day 58 - Beaches, Ports and Views
... should be interesting. In Europe, the big news is still the thousands of immigrants heading Europe but finding the pathways cut off. Many countries are building extensive fences to halt to flow. Largest immigration since World War II. Winter will be harsh for many here.
We enjoyed a nice seafood risotto Jerry prepared for dinner tonight. Tomorrow in the mid-seventies, time for some golf.
Day 57 - Tuscan Coast Cabin
... includes two small port towns of San Stefano and Ercole. Unlike the tight narrow roads of Amalfi, the roads are wide enough to do some touring.
We enjoyed a burgandy beef with gnocchi and some Tuscano red for dinner tonight. Simple but comforting. Comfort food for road weary travelers.
No no pictures today to accompany the blog. Back at it tomorrow!
... was now useless to us since we hadn't planned on being in this new area we really had minimal information. Luckily, Kory by total fluke had downloaded the Tuscany region on his google maps and we were able to use that to sort us out. We passed a group of organized cycle tourists that had come for a week to Tuscany from Vermont. After a short conversation with a few of the participants we rode away both agreeing it wouldn't ...
I want to be alone !!
... numbers. I recall this fear from the Camino to Santiago last year, although in reality there was rarely a problem. Second, this new group seem to have a different mentality when it comes to getting up in the mornings. After being used to waking at 6.30 or 7.00 on my own or with the small group of recent weeks, the first morning after Siena was marked with the rustling of plastic bags and the stuffing of back packs at 5.30am. Yesterday morning was even ...


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"BLING" STYLUS FOR THE TOUCHSCREEN QUEEN! You'll strike the right key every time you text, scroll or do web searches on a smart phone, tablet or other device ... and do it in style. "Jeweled" stylus has a 7 mm, soft, rounded rubber tip that ends finger fumbles and typos on keyboards and screens. Attaches to your phone instantly. 6" L with coiled, stretchable cord. Assorted fun colors.
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The Nike Women's Legendary Waves Pant are both stylish and functional. Made with Dri-FIT fabric to keep you cool and dry alongside flat seams to reduce irritation caused by chaffing.
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The Sofa Beds and Futons - Ratchet Back Sofa Bed with Dark Brown Leather-Like Base by Coaster at Del Sol Furniture in the Phoenix, Glendale, Tempe, Scottsdale, Avondale, Peoria, Goodyear, Litchfield, Arizona area. Product availability may vary. Contact us for the most current availability on this product.
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Your Home is Olde Towne
POLISH TRIANGLE NEW CONSTRUCTION!! Welcome to one of Boston`s HOTTEST Neighborhoods! CITY VIEWS FROM YOUR LIVING ROOM! Just a short walk to South Bay Shopping Center, JFK or Andrew Redline T, South Boston/Dorchester restaurants, beaches and easy highway access to Downtown. Different floor plans and locations to choose from! Brand new units. Boston Street, Washburn Street and Rawson Street. Wide range of ammenities to fit everyones wants and needs.


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HOUSTON -- When an offensive highlight of the night is a double from the pitcher that didn't even lead to a run, it was probably an effort not worthy of distinction.
The Cubs have now gone 59 consecutive innings without holding a lead. The last time they were on top was in the fourth inning last Wednesday at home against the Philadelphia Phillies.
In yet another game over the past week where the Cubs' offense barely made a dent, Alfonso Soriano supplied the only run Tuesday with an impressive home run to left field.
Make that four home runs for Soriano over the past eight games. The bad news is that the Cubs have lost all eight of those games.
Doesn't it figure that once one of the club's power bats finally comes to life that everybody else goes into a slide, including Bryan LaHair, who now has one hit over his last 20 at-bats.
And then there is Starlin Castro, who struck out all four times he came to the plate, including once in the eighth inning with the tying run at third base and one out. His 31 strikeouts are now third most on the club behind sluggers Soriano (32) and LaHair (46). He has just four walks, or the same amount as Reed Johnson has in nearly two-thirds less at-bats.
"We just can't seem to get anything going," manager Dale Sveum said. "You get a guy at third and less than two outs and you get a couple of strikeouts. We just can't get anything out of the ballpark. Soriano hit a solo shot but we just can't seem to get that three-run shot."
The Cubs are now batting .223 (51-for-229) with 20 runs over their last seven games after batting .277 (54-for-195) and scoring 29 runs over their five-game road trip to Milwaukee and St. Louis that ended last Tuesday.
Only Soriano is delivering now after not hitting a home run over the team's first 30 games. He has driven in a run in eight of the team's last 13 games.
"I started hitting homers but it's not enough to win," Soriano said. "It's better to win games. I don't care about my homers because I know I have been doing that for 12 years. The more important thing is to get a win. I don't know what we have to do to win one game and hit more. We're struggling not getting hits so we have to work more."
Batting in the cleanup spot Tuesday, Soriano had a close up view from the on-deck circle of Castro's four strikeouts.
"He's just in his third year in the league so he'll figure it out," Soriano said. "That happened to him last year too. He had little struggles. It's a long season and sometimes you have (struggles) one week or two weeks. But when you get out of your slump you become a better player. I hope when he gets out he will come out hot and be a better player."
Soriano hopes that by everybody continuing to plug away, the offense can finally get in sync.
"I just try to do my job no matter if we're struggling or not," Soriano said. "If you're young or a veteran, everybody has to do their job. I came here to play and try to do my job to make the team better and try to win."


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Season 2 of the Overtime podcast is here! Listen to the first episode with Meg Robichaud now.
Its been over a year and a half since my last attempt at a personal logo (pretty bad concepts and designs now that I look back). Been doing quite a bit of thinking and writing on my personal brand over the last few weeks of who I am and how I want to represent myself. I have a few different concepts in the mix and thought I'd share one with you that I did tonight.
I struggle to find something that represents me, is unique, timeless, adaptable. And I find that you can do a lot with some letters of the alphabet, but I wrestle to find unique things to do with a "t" or "w" or to create an icon to represent me.
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Drug toxicity often goes undetected until clinical trials, the most costly and dangerous phase of drug development. Both the cultures of human cells and animal studies have limitations that cannot be overcome by incremental improvements in the drug testing protocols. A new generation of preclinical models - in form of integrated human tissue platforms, would be transformative to drug screening and predictive modeling of disease. This multiphase (UH2/UH3) proposal integrates in a novel and synergistic way some recent breakthroughs from four leading laboratories, towards developing a vascular/liver/cardiac microtissue system predictive of integrated human physiology. In the UH2 phase, we aim to establish iPS-based vascular, liver and cardiac microtissues providing (i) hierarchical tissue-specific architectures, (ii) functional representation of human biology of health, injury and disease, (iii) real-time biological readouts, and (iv) compatibility with high-throughput/high-content multi-tissue platforms for studies of drug toxicity and over long periods of time (e4 weeks). The work will be done using iPS-derived cells (to provide a large diversity of normal and disease genotypes) and using nondestructive monitoring of the tissue architecture and function (to provide real-time insights into the progression of cell and tissue responses). Our overall hypothesis is that tissue specific structure-function relationship can be achieved through control and biomimetic application of microenvironemental cues in vitro. Such microtissues will then be high-fidelity models for drug testing and toxicology. In the UH3 phase we aim to deploy an integrated cardiac/hepatic/vascular platform and demonstrate its utility for a broad range of genotypes and drugs. Towards these goals, we will pursue a set of coordinated aims with constant feedback, evaluation, and monitoring of the milestones.
Aim 1 is to develop cell-type specific labeling and sensing systems for on-line assessment of tissue architecture and cell function.
Aim 2 is to develop a perfusable branching vascular network serving as a model of the vascular bed and for assembling vascularized liver and cardiac tissues.
Aim 3 is to develop a liver module by assembling hepatic microtissues in hydrogel around the vascular tree.
Aim 4 is to develop a cardiac module by assembling matured cardiac microtissues in hydrogel around the vascular tree.
Aim 5 is to conduct studies of disease susceptibility, for the individual tissue modules and in the multi-tissue platform.
Aim 6 is to investigate human physiology and disease in multi-tissue platforms. This way, we aim to develop a radically new technology for studies of drugs in human tissue models. If successful, the proposed approach would radically enhance the translation of drug discovery into human applications, by enabling accurate preclinical data for better, faster and cheaper clinical trials.
Broader Impact We propose to engineer three different microtissues highly resembling the structure and normal function of human capillary network, liver lobule and heart muscle, and to use these microtissues for screening of drugs and study of disease under conditions representative of whole bodyphysiology. To enable personalized approach to evaluation of drug regimens and study of disease, we will use adult stem cells derived from small samples of the patient's skin. This technology could greatly accelerate translation of discovery into new therapeutic modalities for the patients in need.
|Hirschi, Karen K; Li, Song; Roy, Krishnendu (2014) Induced pluripotent stem cells for regenerative medicine. Annu Rev Biomed Eng 16:277-94
|Cimetta, Elisa; Vunjak-Novakovic, Gordana (2014) Microscale technologies for regulating human stem cell differentiation. Exp Biol Med (Maywood) 239:1255-63
|Bhatia, Sangeeta N; Underhill, Gregory H; Zaret, Kenneth S et al. (2014) Cell and tissue engineering for liver disease. Sci Transl Med 6:245sr2
|Martins, Ana M; Vunjak-Novakovic, Gordana; Reis, Rui L (2014) The current status of iPS cells in cardiac research and their potential for tissue engineering and regenerative medicine. Stem Cell Rev 10:177-90
|Martin, Kathleen A; Hirschi, Karen K (2014) The magic touch: endothelial cells muscle-up adipose. Circ Res 115:752-4
|Co?kun, Süleyman; Chao, Hsu; Vasavada, Hema et al. (2014) Development of the fetal bone marrow niche and regulation of HSC quiescence and homing ability by emerging osteolineage cells. Cell Rep 9:581-90
|Galie, Peter A; Nguyen, Duc-Huy T; Choi, Colin K et al. (2014) Fluid shear stress threshold regulates angiogenic sprouting. Proc Natl Acad Sci U S A 111:7968-73
|Freytes, Donald O; O'Neill, John D; Duan-Arnold, Yi et al. (2014) Natural cardiac extracellular matrix hydrogels for cultivation of human stem cell-derived cardiomyocytes. Methods Mol Biol 1181:69-81
|Li, Cheri Y; Stevens, Kelly R; Schwartz, Robert E et al. (2014) Micropatterned cell-cell interactions enable functional encapsulation of primary hepatocytes in hydrogel microtissues. Tissue Eng Part A 20:2200-12
|Shlomai, Amir; Schwartz, Robert E; Ramanan, Vyas et al. (2014) Modeling host interactions with hepatitis B virus using primary and induced pluripotent stem cell-derived hepatocellular systems. Proc Natl Acad Sci U S A 111:12193-8
Showing the most recent 10 out of 13 publications


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Mormon Mommy Blogs has been internationally recognized as one of the Top 100 Christian Blogs for Women, and we're pretty popular with the news media. In fact, we're pretty sure Germany would marry us if they could, but they can't, because we don't believe in polygamy. Also: I don't think you're allowed to marry whole countries... we'll look into that.
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Dieter Van Tornhout hails best moment of his career
The Kilmarnock striker says his goal against Celtic at Hampden was 'like a dream'.
Kilmarnock's League Cup match winner Dieter Van Tornhout says his goal in Sunday's final was the best moment of his career so far.
The Belgian striker headed home Lee Johnson's cross in the 84th minute to take the trophy to Rugby Park for the very first time. Van Tornhout, who turned 27 on Sunday, was a second-half substitute replacing Gary Harkins after 73 minutes.
He joined Kenny Shiels' men in January after terminating his contract with Cypriot side Nea Salamina.
And speaking to STV, the former Club Brugge man described his feelings after seeing the ball hit the back of the net.
He said: "It was incredible, an amazing feeling. It was a perfect cross and it was not so difficult to put my head on the ball.
"It was amazing to celebrate with the many supporters who were there. It was perfect.
"It was the best moment of my career because it won us the cup.
"The fans were super, they supported us a lot and to celebrate with my team-mates on the pitch was an amazing feeling.
"It's like a dream because you join a new team, you try to do your best as much as possible and if something happens like this then it is super."


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1934 â, 30 Ave SW CALGARY ALBERTA T2T 1P9
5524 2nd Street SW CALGARY ALBERTA T2H 0G9
1919b CALGARY ALBERTA T2S 1W4
Suite 901 Sw 1015 Fourth Street CALGARY ALBERTA T2R 1J4
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