text: Do you like croissants and macaroons? This place has both in loads! Their croissants are buttery, flaky, warm, and flavorful. They have croissants with all kinds of fillings, but you can't go wrong with a plain either! Definitely the best croissant I have tried in Miami, hands down. They also have many flavors of macaroons and the 5-6 I have... More


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Despite the success of highly active anti-retroviral therapy in controlling virus replication in HIV-1 positive individuals, problems such as drug resistance and side effects often compromise the effectiveness of anti-HIV- 1 drug. Therefore, new anti-HIV agents with novel mechanisms of action are needed. In an effort to identify novel anti-HIV-1 agents, we have developed potent betulinic acid (BA) derivatives that inhibit HIV-1 maturation. These compounds are structurally and mechanistically novel when compared to the drugs currently used for AIDS therapy. Their potentials for treatment of AIDS are currently being evaluated under different stages of preclinical or clinical studies. Bevirimat is at the most advanced stage of drug development among the anti- HIV-1 BA derivatives. Although bevirimat is a potent HIV-1 maturation inhibitor, results of phase II clinical trials indicate that it is less effective in a subset (30-40%) of HIV-1 positive individuals. Therefore, bevirimat analogs that can overcome this high baseline drug resistance are expected to have great potential to be developed into anti-HIV-1 drugs. The objective of this study is to synthesize bevirimat analogs that overcome the high baseline drug resistance. We have previously identified the C3 side chain as the anti-HIV-1 maturation pharmacophore of bevirimat. We hypothesize that suitable modifications of the pharmacophore will create a new class of bevirimat analogs that are effective against the drug resistant viruses. We plan to test this hypothesis and accomplish the objective of this study with the following Specific Aims: (1) to synthesize BA derivatives with optimized pharmacophores. (2) To identify new terpenoid scaffolds and auxiliary groups for the synthesis of new anti-maturation inhibitors against the drug resistant viruses. (3) To determine the drug binding site and mechanism of action of the anti-HIV-1 maturation BA derivatives. Aside from the high baseline drug resistance to bevirimat, results from clinical trials have been promising. The proposed study is expected to overcome this drug resistance and, as a result, will have a high impact on developing a class of novel anti-HIV-1 maturation inhibitors for AIDS therapy.
The goal of the proposed study is to develop potent anti-HIV-1 agents that can overcome the drug resistance associated with the HIV-1 maturation inhibitor bevirimat. Aside from the high baseline drug resistance to bevirimat, results of clinical trials have been very successful. The proposed study is expected to overcome this drug resistance and, as a result, will have high impact on developing anti-HIV-1 maturation inhibitors for AIDS therapy.
|Dang, Zhao; Ho, Phong; Zhu, Lei et al. (2013) New betulinic acid derivatives for bevirimat-resistant human immunodeficiency virus type-1. J Med Chem 56:2029-37
|Whisnant, Adam W; Bogerd, Hal P; Flores, Omar et al. (2013) In-depth analysis of the interaction of HIV-1 with cellular microRNA biogenesis and effector mechanisms. MBio 4:e000193
|Tian, Xingtao; Qin, Bingjie; Wu, Zhiyuan et al. (2010) Design, synthesis, and evaluation of diarylpyridines and diarylanilines as potent non-nucleoside HIV-1 reverse transcriptase inhibitors. J Med Chem 53:8287-97
|Tian, Xingtao; Qin, Bingjie; Lu, Hong et al. (2009) Discovery of diarylpyridine derivatives as novel non-nucleoside HIV-1 reverse transcriptase inhibitors. Bioorg Med Chem Lett 19:5482-5
|Huang, Li; Chen, Chin Ho (2009) Proteasome regulators: activators and inhibitors. Curr Med Chem 16:931-9
|Dang, Zhao; Lai, Weihong; Qian, Keduo et al. (2009) Betulinic acid derivatives as human immunodeficiency virus type 2 (HIV-2) inhibitors. J Med Chem 52:7887-91
|Huang, Li; Yu, Donglei; Ho, Phong et al. (2008) Synthesis and proteasome inhibition of glycyrrhetinic acid derivatives. Bioorg Med Chem 16:6696-701
|Lai, Weihong; Huang, Li; Ho, Phong et al. (2008) Betulinic acid derivatives that target gp120 and inhibit multiple genetic subtypes of human immunodeficiency virus type 1. Antimicrob Agents Chemother 52:128-36
|Huang, Li; Ho, Phong; Chen, Chin-Ho (2007) Activation and inhibition of the proteasome by betulinic acid and its derivatives. FEBS Lett 581:4955-9
|Traina-Dorge, Vicki L; Martin, Louis N; Lorino, Rebecca et al. (2007) Human T cell leukemia virus type 1 up-regulation after simian immunodeficiency virus-1 coinfection in the nonhuman primate. J Infect Dis 195:562-71
Showing the most recent 10 out of 12 publications

subset: commoncrawl


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Reviewed By Greg R (Saint Louis, MO) Reviewed for a 2000 Lexus RX 300 —2/9/2017 9:01 PM
Great value...fits great...I made the right choice!!
Reviewed By Joel R (Los Gatos, CA) Reviewed for a 2017 Maserati Quattroporte —1/15/2017 10:57 AM
Great concept. The mat did not fit at first as it was not a 100% customized fit. But that was not the concept of this rear cargo mat since it is a customizable fit--meaning you trim it to fit your needs. What a cool concept. I installed it the very day it arrived. It's now a perfect fit! You will not be disappointed. (Used a hard surface and straight razor blade to trim as need for my vehicle's trunk size needs.)


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A group of 14 chefs gathered in Lapland, Finland, earlier this month to create a dinner out of locally foraged ingredients as part of an ongoing program designed to find more eco-friendly ways of preparing food. The group created the first dinner in advance of the 2009 U.N. Climate Change Conference in Copenhagen, and has moved to a new city for each successive meal.
Full Story:MSNBC


text:
super sixes
Who doesn't love a list? These are our pick of the best events from beginner triathlons to the toughest 10k's.
This challenging evening race follows a 10k out and back course on picturesque traffic free country lanes, starting and finishing in Sanders Park, Bromsgrove. Part of the Bromsgrove Carnival weekend, the race is now in its 14th year and has become a key event in the Bromsgrove sporting calendar. There's music en route, the friendliest marshals in the whole of Bromsgrove, and hills. Oh yes, lots of hills. (date tbc)
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Drive Excellence in Your Customer Operations
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Tropical Fish Keeping - Aquarium fish care and resources (http://www.tropicalfishkeeping.com/forum.php)
- Freshwater Aquarium Equipment (http://www.tropicalfishkeeping.com/freshwater-aquarium-equipment/)
- - Shocked! I used Algone and my problems are 'ALLgone' (http://www.tropicalfishkeeping.com/freshwater-aquarium-equipment/shocked-i-used-algone-my-problems-5062/)
Shocked! I used Algone and my problems are 'ALLgone'
I had a bacterial bloom issue in one tank and diatom in the other. I posted here asking if anyone had ever used Algone. I only got responses from 2 members if I remember correctly, but they were positive. I just wanted to let everyone here know my experience. I sent an email to the company, the person who replies is named Thilo, and he seemed fairly knowledgeable. I didn't want to wait and do mail order, so I went to my LFS and bought a pack of 6 for $9.99.
WOW! I cleaned both tanks, put the algone pouch in the filter and in 7 days time I have no more cloudy water, no more diatom, nada-nothing! The bags are basically plants in a pouch, and pick up all sorts of crap in the water that eventually makes a smelly slime, full of bad bacteria, on the pouch which means it's time for change.
If anyone has any "issues" give Algone a try. I am sold on it. I am the last person to fall for a product that makes any promises, but this time I was surprised!
i actually got one of them in my tank as part of the package. initially i was just going to throw it out but ill keep a hold of it now
thanks for sharing
Ditto Julie:
Thanks for the post.
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text:
Maybe it is true what they say
Poets only prosper when they are prey
Only the tortured soul
Only the weeping and discarded
Only the hurt and dying can scrawl with their blood a rhyme experienced in full
I say nay
Pain is one emotion
Pain is but a moment in forever
Pain comes to the poet be it from a woman or a seat with out a cushion
But maybe it is true what they say
Poets only prosper when they must pay
© Copyright 2017 Cody S. D. Crum. All rights reserved.
Status: Finished
Genre: Poetry
Yeah I agree with you. Nothing great ever comes without a sacrifice. Loved reading it. Regards:)
i really like it, it's kind of unique and really flows,
I particularily enjoyed the repeated lines 'poets only prosper when they are prey/must pay', I think it rounds out the poem very nicely and brings the purported question full-circle. Personally, while there certainly are many notable examples of the tormented genius, I've always felt that the idea of the tortured artist suffering for his work is a rather tired, self-perpetuating myth and I like how you bring this question to the forefront by saying 'pain is one emotion', I think this is a perfect way of expressing doubt in this popular myth; that suffering some how has a monopoly on compelling art. I don't know about you but I've never suffered for my work, I love writing and most things I write about I've never experienced, it's pure imagination.
Willet, we seem to be very like minded.
I am a happy, half way successful young man trying to claw in to the middle class, with a fiance; and many of my friends have dared to label me "Boring", far from disturbed or tortured. And on that note, I mostly write horror and thriller stories.
I believe poetry is a great way to express anguish and hurt. But that is not all poetry, or what poetry is all about.
I'm glad you liked it, and I much appreciate your feed back.
i totally agree.. yar it was too gooooood .. :) :) i like it
Short Story / Horror
Short Story / Thrillers
Short Story / Horror
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Rangers 9, A's 7: Ian Kinsler hit a leadoff homer to start a five-run first inning, Matt Harrison got his 18th victory and the two-time defending American League champions held on for a victory over visiting Oakland. The Rangers are one victory from clinching a playoff berth.
Tigers 5, Royals 4: Doug Fister set an AL record by striking out nine consecutive batters, and host Detroit kept its lead in the Central, beating Kansas City on Alex Avila's grounder in the ninth inning.
Blue Jays 6, Yankees 0: Brandon Morrow and two relievers combined on a five-hitter, pitching Toronto to a victory that trimmed host New York's tight lead in the AL East. New York lost for the third time in five games and wasted a chance to go two up with six to play.
Rays 3, White Sox 2: Evan Longoria hit a tiebreaking homer in the ninth inning, and surging Tampa Bay won its eighth game in a row, handing Chicago a loss that hurts its playoff hopes.
Mets 6, Pirates 5: R.A. Dickey became the first knuckleballer to win 20 games in more than three decades, matching his career high with 13 strikeouts and leading host New York over Pittsburgh behind David Wright's tiebreaking, three-run homer.
Reds 2, Brewers 1: Slumping rookie Todd Frazier tied the game with a two-out homer in the ninth inning, Dioner Navarro hit an RBI triple moments later and Cincinnati dealt a major setback to visiting Milwaukee's playoff chances.
Nationals 7, Phillies 3: Gio Gonzalez became the first 21-game winner in the majors, Michael Morse hit two homers and Washington beat host Philadelphia to move closer to an NL East title.
Braves 6, Marlins 2: David Ross and Andrelton Simmons raced home on left fielder Bryan Petersen's costly error, sending Tommy Hanson and Atlanta to a victory over visiting Miami.
Giants 7, Diamondbacks 3: Midseason acquisitions Hunter Pence and Marco Scutaro each hit a two-run homer in the second inning to back Barry Zito, and NL West champion San Francisco beat visiting Arizona in their regular-season home finale.
Rockies 7, Cubs 5: Jordan Pacheco and DJ LeMahieu homered, leading host Colorado over Chicago for a three-game sweep.
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SkPower Fiat x1/9 VS Nissan GTR Power Fest Slovakia Ring 2012 superfinale
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Fiat X1/9 insanity
Jeff tried to kill me today. again


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2015, Volume 064, Issue i11
- BatchJobs and BatchExperiments: Abstraction Mechanisms for Using R in Batch Environments
by Bischl, Bernd & Lang, Michel & Mersmann, Olaf & Rahnenführer, Jörg & Weihs, Claus
2015, Volume 064, Issue i10
- gems: An R Package for Simulating from Disease Progression Models
by Blaser, Nello & Vizcaya, Luisa Salazar & Estill, Janne & Zahnd, Cindy & Kalesan, Bindu & Egger, Matthias & Gsponer, Thomas & Keiser, Olivia
2015, Volume 064, Issue i09
- nparcomp: An R Software Package for Nonparametric Multiple Comparisons and Simultaneous Confidence Intervals
by Konietschke, Frank & Placzek, Marius & Schaarschmidt, Frank & Hothorn, Ludwig A.
2015, Volume 064, Issue i08
2015, Volume 064, Issue i07
- PReMiuM: An R Package for Profile Regression Mixture Models Using Dirichlet Processes
by Liverani, Silvia & Hastie, David I. & Azizi, Lamiae & Papathomas, Michail & Richardson, Sylvia
2015, Volume 064, Issue i06
- NHPoisson: An R Package for Fitting and Validating Nonhomogeneous Poisson Processes
by Cebrián, Ana C. & Abaurrea, Jesús & Asín, Jesús
2015, Volume 064, Issue i05
- Constructing and Modifying Sequence Statistics for relevent Using informR in R
by Marcum, Christopher Steven & Butts, Carter T.
2015, Volume 064, Issue i04
- fitdistrplus: An R Package for Fitting Distributions
by Delignette-Muller, Marie Laure & Dutang, Christophe
2015, Volume 064, Issue i03
- Exploring Diallelic Genetic Markers: The HardyWeinberg Package
by Graffelman, Jan
2015, Volume 064, Issue i02
- Fitting Heavy Tailed Distributions: The poweRlaw Package
by Gillespie, Colin S.
2015, Volume 064, Issue i01
- iqLearn: Interactive Q-Learning in R
by Linn, Kristin A. & Laber, Eric B. & Stefanski, Leonard A.
2015, Volume 064, Issue c02
- SDD: An R Package for Serial Dependence Diagrams
by Bagnato, Luca & De Capitani, Lucio & Mazza, Angelo & Punzo, Antonio
2015, Volume 064, Issue c01
- Building a Nomogram for Survey-Weighted Cox Models Using R
by Capanu, Marinela & Gönen, Mithat
2015, Volume 063, Issue i21
- Structured Additive Regression Models: An R Interface to BayesX
by Umlauf, Nikolaus & Adler, Daniel & Kneib, Thomas & Lang, Stefan & Zeileis, Achim
2015, Volume 063, Issue i20
- Spatial Data Analysis with R-INLA with Some Extensions
by Bivand, Roger & Gómez-Rubio, Virgilio & Rue, Håvard
2015, Volume 063, Issue i19
- Bayesian Spatial Modelling with R-INLA
by Lindgren, Finn & Rue, Håvard
2015, Volume 063, Issue i18
- Comparing Implementations of Estimation Methods for Spatial Econometrics
by Bivand, Roger & Piras, Gianfranco
2015, Volume 063, Issue i17
- GWmodel: An R Package for Exploring Spatial Heterogeneity Using Geographically Weighted Models
by Gollini, Isabella & Lu, Binbin & Charlton, Martin & Brunsdon, Christopher & Harris, Paul
2015, Volume 063, Issue i16
- SPODT: An R Package to Perform Spatial Partitioning
by Gaudart, Jean & Graffeo, Nathalie & Coulibaly, Drissa & Barbet, Guillaume & Rebaudet, Stanilas & Dessay, Nadine & Doumbo, Ogobara K. & Giorgi, Roch
2015, Volume 063, Issue i15
- spTimer: Spatio-Temporal Bayesian Modeling Using R
by Bakar, Khandoker Shuvo & Sahu, Sujit K.
2015, Volume 063, Issue i14
- spate: An R Package for Spatio-Temporal Modeling with a Stochastic Advection-Diffusion Process
by Sigrist, Fabio & Künsch, Hans R. & Stahel, Werner A.
2015, Volume 063, Issue i13
- spBayes for Large Univariate and Multivariate Point-Referenced Spatio-Temporal Data Models
by Finley, Andrew O. & Banerjee, Sudipto & Gelfand, Alan E.
2015, Volume 063, Issue i12
- Model-Based Geostatistics the Easy Way
by Brown, Patrick E.
2015, Volume 063, Issue i11
- geoCount: An R Package for the Analysis of Geostatistical Count Data
by Jing, Liang & De Oliveira, Victor
2015, Volume 063, Issue i10
- Parallelizing Gaussian Process Calculations in R
by Paciorek, Christopher J. & Lipshitz, Benjamin & Zhuo, Wei & Prabhat, . & Kaufman, Cari G. G. & Thomas, Rollin C.
2015, Volume 063, Issue i09
- Analysis of Random Fields Using CompRandFld
by Padoan, Simone A. & Bevilacqua, Moreno
2015, Volume 063, Issue i08
- Analysis, Simulation and Prediction of Multivariate Random Fields with Package RandomFields
by Schlather, Martin & Malinowski, Alexander & Menck, Peter J. & Oesting, Marco & Strokorb, Kirstin
2015, Volume 063, Issue i07
- Bayesian Inference and Data Augmentation Schemes for Spatial, Spatiotemporal and Multivariate Log-Gaussian Cox Processes in R
by Taylor, Benjamin M. & Davies, Tilman M. & Rowlingson, Barry S. & Diggle, Peter J.
2015, Volume 063, Issue i06
- ads Package for R: A Fast Unbiased Implementation of the K-function Family for Studying Spatial Point Patterns in Irregular-Shaped Sampling Windows
by Pélissier, Raphaël & Goreaud, François
2015, Volume 063, Issue i05
- plotKML: Scientific Visualization of Spatio-Temporal Data
by Hengl, Tomislav & Roudier, Pierre & Beaudette, Dylan & Pebesma, Edzer
2015, Volume 063, Issue i04
- RgoogleMaps and loa: Unleashing R Graphics Power on Map Tiles
by Loecher, Markus & Ropkins, Karl
2015, Volume 063, Issue i03
- micromapST: Exploring and Communicating Geospatial Patterns in US State Data
by Pickle, Linda Williams & Pearson, James B. & Carr, Daniel B.
2015, Volume 063, Issue i02
- micromap: A Package for Linked Micromaps
by Payton, Quinn C. & McManus, Michael G. & Weber, Marc H. & Olsen, Anthony R. & Kincaid, Thomas M.
2015, Volume 063, Issue i01
- Software for Spatial Statistics
by Pebesma, Edzer & Bivand, Roger & Ribeiro, Paulo Justiniano
2015, Volume 063, Issue c01
- Pitfalls in the Implementation of Bayesian Hierarchical Modeling of Areal Count Data: An Illustration Using BYM and Leroux Models
by Gerber, Florian & Furrer, Reinhard
2015, Volume 062, Issue i09
- vSMC: Parallel Sequential Monte Carlo in C++
by Zhou, Yan
2015, Volume 062, Issue i08
- envlp: A MATLAB Toolbox for Computing Envelope Estimators in Multivariate Analysis
by Cook, R. Dennis & Su, Zhihua & Yang, Yi
2015, Volume 062, Issue i07
- ecp: An R Package for Nonparametric Multiple Change Point Analysis of Multivariate Data
by James, Nicholas A. & Matteson, David S.
2015, Volume 062, Issue b01
- Multilevel Modeling Using R
by Grömping, Ulrike
2014, Volume 062, Issue i06
- D-STEM: A Software for the Analysis and Mapping of Environmental Space-Time Variables
by Finazzi, Francesco & Fassò, Alessandro
2014, Volume 062, Issue i05
- c060: Extended Inference with Lasso and Elastic-Net Regularized Cox and Generalized Linear Models
by Sill, Martin & Hielscher, Thomas & Becker, Natalia & Zucknick, Manuela
2014, Volume 062, Issue i04
- TPmsm: Estimation of the Transition Probabilities in 3-State Models
by Araújo, Artur & Meira-Machado, Luís & Roca-Pardiñas, Javier
2014, Volume 062, Issue i03
- Learning Continuous Time Bayesian Network Classifiers Using MapReduce
by Villa, Simone & Rossetti, Marco
2014, Volume 062, Issue i02
- Seasonal Adjustment with the R Packages x12 and x12GUI
by Kowarik, Alexander & Meraner, Angelika & Templ, Matthias & Schopfhauser, Daniel
2014, Volume 062, Issue i01
- TSclust: An R Package for Time Series Clustering
by Montero, Pablo & Vilar, José A.
2014, Volume 061, Issue i13
- BayesLCA: An R Package for Bayesian Latent Class Analysis
by White, Arthur & Murphy, Thomas Brendan
2014, Volume 061, Issue i12
- coneproj: An R Package for the Primal or Dual Cone Projections with Routines for Constrained Regression
by Liao, Xiyue & Meyer, Mary C.
2014, Volume 061, Issue i11
- Fitting Accelerated Failure Time Models in Routine Survival Analysis with R Package aftgee
by Chiou, Sy Han & Kang, Sangwook & Yan, Jun
2014, Volume 061, Issue i10
2014, Volume 061, Issue i09
- NPCirc: An R Package for Nonparametric Circular Methods
by Oliveira, María & Crujeiras, Rosa M. & Rodríguez-Casal, Alberto
2014, Volume 061, Issue i08
- OptimalCutpoints: An R Package for Selecting Optimal Cutpoints in Diagnostic Tests
by López-Ratón, Mónica & Rodríguez-Álvarez, María Xosé & Cadarso-Suárez, Carmen & Gude-Sampedro, Francisco
2014, Volume 061, Issue i07
- WebBUGS: Conducting Bayesian Statistical Analysis Online
by Zhang, Zhiyong
2014, Volume 061, Issue i06
- NbClust: An R Package for Determining the Relevant Number of Clusters in a Data Set
by Charrad, Malika & Ghazzali, Nadia & Boiteau, Véronique & Niknafs, Azam
2014, Volume 061, Issue i05
- Natter: A Python Natural Image Statistics Toolbox
by Sinz, Fabian H. & Lies, Jörn-Philipp & Gerwinn, Sebastian & Bethge, Matthias
2014, Volume 061, Issue i04
- SamplingStrata: An R Package for the Optimization of Stratified Sampling
by Barcaroli, Giulio
2014, Volume 061, Issue i03
- ldr: An R Software Package for Likelihood-Based Su?cient Dimension Reduction
by Adragni, Kofi Placid & Raim, Andrew M.
2014, Volume 061, Issue i02
- Bergm: Bayesian Exponential Random Graphs in R
by Caimo, Alberto & Friel, Nial
2014, Volume 061, Issue i01
- evtree: Evolutionary Learning of Globally Optimal Classification and Regression Trees in R
by Grubinger, Thomas & Zeileis, Achim & Pfeiffer, Karl-Peter
2014, Volume 061, Issue c02
- mdscore: An R Package to Compute Improved Score Tests in Generalized Linear Models
by da Silva-Júnior, Antonio Hermes M. & da Silva, Damião Nóbrega & Ferrari, Silvia L. P.
2014, Volume 061, Issue c01
- Tutorial: Survival Estimation for Cox Regression Models with Time-Varying Coe?cients Using SAS and R
by Thomas, Laine & Reyes, Eric M.
2014, Volume 061, Issue b02
- Implementing Reproducible Research
by Wilson, Brigid
2014, Volume 061, Issue b01
- XML and Web Technologies for Data Sciences with R
by Munzert, Simon
2014, Volume 060, Issue i06
- Continuous Global Optimization in R
by Mullen, Katharine M.
2014, Volume 060, Issue i05
- Convex Optimization in R
by Koenker, Roger & Mizera, Ivan
2014, Volume 060, Issue i04
2014, Volume 060, Issue i03
- Spectral Projected Gradient Methods: Review and Perspectives
by Birgin, Ernesto G. & Martínez, Jose Mario & Raydan, Marcos
2014, Volume 060, Issue i02
- On Best Practice Optimization Methods in R
by Nash, John C.
2014, Volume 060, Issue i01
- Numerical Optimization in R: Beyond optim
by Varadhan, Ravi
2014, Volume 059, Issue i13
- structSSI: Simultaneous and Selective Inference for Grouped or Hierarchically Structured Data
by Sankaran, Kris & Holmes, Susan
2014, Volume 059, Issue i12
- Capabilities of R Package mixAK for Clustering Based on Multivariate Continuous and Discrete Longitudinal Data
by Komárek, Arnot & Komárková, Lenka
2014, Volume 059, Issue i11
- hmmm: An R Package for Hierarchical Multinomial Marginal Models
by Colombi, Roberto & Giordano, Sabrina & Cazzaro, Manuela
2014, Volume 059, Issue i10
- Tidy Data
by Wickham, Hadley
2014, Volume 059, Issue i09
- A Kenward-Roger Approximation and Parametric Bootstrap Methods for Tests in Linear Mixed Models The R Package pbkrtest
by Halekoh, Ulrich & Højsgaard, Søren
2014, Volume 059, Issue i08
- dglars: An R Package to Estimate Sparse Generalized Linear Models
by Augugliaro, Luigi & Mineo, Angelo & Wit, Ernst C.
2014, Volume 059, Issue i07
2014, Volume 059, Issue i06
- phtt: Panel Data Analysis with Heterogeneous Time Trends in R
by Bada, Oualid & Liebl, Dominik
2014, Volume 059, Issue i05
- mediation: R Package for Causal Mediation Analysis
by Tingley, Dustin & Yamamoto, Teppei & Hirose, Kentaro & Keele, Luke & Imai, Kosuke
2014, Volume 059, Issue i04
- General Purpose Convolution Algorithm in S4 Classes by Means of FFT
by Ruckdeschel, Peter & Kohl, Matthias
2014, Volume 059, Issue i03
- ART: A Data Aggregation Program for the Behavioral Sciences
by Lang, Albert-Georg
2014, Volume 059, Issue i02
- The R Package survsim for the Simulation of Simple and Complex Survival Data
by Moriña, David & Navarro, Albert
2014, Volume 059, Issue i01
- cancerclass: An R Package for Development and Validation of Diagnostic Tests from High-Dimensional Molecular Data
by Jan, Budczies & Kosztyla, Daniel & von Törne, Christian & Stenzinger, Albrecht & Darb-Esfahani, Silvia & Dietel, Manfred & Denkert, Carsten
2014, Volume 059, Issue c03
- Nestedness for Dummies (NeD): A User-Friendly Web Interface for Exploratory Nestedness Analysis
by Strona, Giovanni & Galli, Paolo & Seveso, Davide & Montano, Simone & Fattorini, Simone
2014, Volume 059, Issue c02
2014, Volume 059, Issue c01
- deltaPlotR: An R Package for Di?erential Item Functioning Analysis with Ango? s Delta Plot
by Magis, David & Facon, Bruno
2014, Volume 058, Issue s01
- Statistical Software (R, SAS, SPSS, and Minitab) for Blind Students and Practitioners
by Godfrey, A. Jonathan R. & Loots, M. Theodor
2014, Volume 058, Issue i12
- Regularization Paths for Conditional Logistic Regression: The clogitL1 Package
by Reid, Stephen & Tibshirani, Rob
2014, Volume 058, Issue i11
- Optimal Asset Pricing
by Turner, Rolf & Banerjee, Pradeep & Shahlori, Rayomand
2014, Volume 058, Issue i10
- movMF: An R Package for Fitting Mixtures of von Mises-Fisher Distributions
by Hornik, Kurt & Grün, Bettina
2014, Volume 058, Issue i09
- copulaedas: An R Package for Estimation of Distribution Algorithms Based on Copulas
by Gonzalez-Fernandez, Yasser & Soto, Marta
2014, Volume 058, Issue i08
- %HPGLIMMIX: A High-Performance SAS Macro for GLMM Estimation
by Xie, Liang & Madden, Laurence V.
2014, Volume 058, Issue i07
- conting: An R Package for Bayesian Analysis of Complete and Incomplete Contingency Tables
by Overstall, Antony M. & King, Ruth
2014, Volume 058, Issue i06
- KernSmoothIRT: An R Package for Kernel Smoothing in Item Response Theory
by Mazza, Angelo & Punzo, Antonio & McGuire, Brian
2014, Volume 058, Issue i05
- Smoothing Spline ANOVA Models: R Package gss
by Gu, Chong
2014, Volume 058, Issue i04
- Hierarchical Archimedean Copulae: The HAC Package
by Okhrin, Ostap & Ristig, Alexander
2014, Volume 058, Issue i03
- changepoint: An R Package for Changepoint Analysis
by Killick, Rebecca & Eckley, Idris A.
2014, Volume 058, Issue i02
- R Marries NetLogo: Introduction to the RNetLogo Package
by Thiele, Jan C
2014, Volume 058, Issue i01
- Flexible Generation of E-Learning Exams in R: Moodle Quizzes, OLAT Assessments, and Beyond
by Zeileis, Achim & Umlauf, Nikolaus & Leisch, Friedrich
2014, Volume 058, Issue b02
- Growth Curve Analysis and Visualization Using R
by Wiley, Joshua F.
2014, Volume 058, Issue b01
- Analyzing Spatial Models of Choice and Judgment with R
by Evans, Gary
2014, Volume 057, Issue i14
- truncSP: An R Package for Estimation of Semi-Parametric Truncated Linear Regression Models
by Karlsson, Maria & Lindmark, Anita
2014, Volume 057, Issue i13
2014, Volume 057, Issue i12
- Building Bivariate Tables: The compareGroups Package for R
by Subirana, Isaac & Sanz, Héctor & Vila, Joan
2014, Volume 057, Issue i11
- Clustering via Nonparametric Density Estimation: The R Package pdfCluster
by Azzalini, Adelchi & Menardi, Giovanna
2014, Volume 057, Issue i10
- PaCAL: A Python Package for Arithmetic Computations with Random Variables
by Korzeń, Marcin & Jaroszewicz, Szymon
2014, Volume 057, Issue i09
- A SAS Package for Logistic Two-Phase Studies
by Schill, Walter & Enders, Dirk & Drescher, Karsten
2014, Volume 057, Issue i08
- R Package multiPIM: A Causal Inference Approach to Variable Importance Analysis
by Ritter, Stephan J & Jewell, Nicholas P & Hubbard, Alan E
2014, Volume 057, Issue i07
- Three-Way Component Analysis Using the R Package ThreeWay
by Giordani, Paolo & Kiers, Henk A. L. & Del Ferraro, Maria Antonietta
2014, Volume 057, Issue i06
- PySSM: A Python Module for Bayesian Inference of Linear Gaussian State Space Models
by Strickland, Christopher & Burdett, Robert & Mengersen, Kerrie & Denham, Robert


text:
$50,000 Expanding Table
More Stats +/-
Luxurious Tea Humidors
Customized Humidity Appliances
Automated News Writing Software
Interactive Inner Strength Installations
Agricultural-Business Connection Platforms
Fletcher Capstan Table
Apr 12, 2007By: POPEYE -
References: dbfletcher & freshcreation.nl
References: dbfletcher & freshcreation.nl
For a fantastic design and space saving idea, check out the Fletcher Capstan Table. The expansion video is very cool. However, this cool table comes with a catch. It'll cost you £25,000 to £35,000 ($50,000 to $70,000). The company's site describes, "It is a round table which, when rotated at its outer perimeter, amazingly doubles its seating capacity and, just as astonishingly, remains truly circular. Very importantly it stores its expansion leaves within itself. Existing tables can seat six persons when small, and twelve or more when expanded, but there are other design possibilities. Operation, which has been described as 'pure magic' by Boat International magazine, really is a sight to behold and extremely quick, it taking only three seconds to complete an entire expansion or reduction cycle."


text:
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User:Red Phoenix
|I did everything I set out to do, albeit with a little contention. Until I find what it is I'd like to write about next and have that zest, you'll probably find me working on my next novel... URL not provided to prevent self-advertisement. Therefore, for the moment... Red Phoenix let's talk... is taking a short wikibreak and will be back on Wikipedia soon.
|This is a Wikipedia user page.
This is not an encyclopedia article. If you find this page on any site other than Wikipedia, you are viewing a mirror site. Be aware that the page may be outdated and that the user to whom this page belongs may have no personal affiliation with any site other than Wikipedia itself. The original page is located at https://en.wikipedia.org/wiki/User:Red_Phoenix.
|Search user languages
|Nothing great has ever been accomplished without enthusiasm.
|— Ralph Waldo Emerson
|Don't give up. Don't ever give up.
|— Jim Valvano
|To be this good takes AGES. To be this good takes SEGA.
|— Sega
Hello, my name is Red Phoenix.
Yes, that's an internet handle and not my real name. I choose not to disclose my real name publicly. The inspiration for the name came to be in 2007, coming from the legendary figure of the phoenix, and I've used it ever since. I joined Wikipedia in August 2007 as Redphoenix526 in order to make some updates without showing my IP address, and well, I'm still here today. How that is, I'm not really sure, but I'm glad.
A little about me[edit]
I'm employed as an assistant manager with a national retailer in the United States and I have a Bachelor of Science degree in Biology from Purdue University. I'm a proud Hoosier, born and raised. I'm also an author of fantasy fiction in my spare time, though it's just a hobby at this point. Ever since I was young, I have always been a fan of Sega consoles and video games, and have remained a member of the Sega task force of WikiProject Video games. More than that, though, I've enjoyed working in Wikipedia's functional areas, including WP:AFD, WP:GAN, and continued work with the Video games WikiProject, especially the Sega task force.
After starting in August 2007, I retired in July 2008 after a failed RFA and rampant drama running in the Sega task force, where I spent most of my time. I began to grow distant from the community I had worked with and just as well saw how much time Wikipedia was taking away from my college studies, because I could not put it down. During my year here, I had a few great contributions, including getting Crush 40 and Sega Genesis to GA status, as well as List of Sega 32X games to FL status, when the standards for each status level were more loosely interpreted than they are now, and referencing did not require such lofty standards for reliability. All were delisted after I retired, but in a way I think that's a good thing because being six years older I can see more that can be done with each.
I returned in May 2013, and I don't have any plans to leave soon. Even during my time of inactivity, I did frequently check Wikipedia and my user pages to see if anything was going on. It feels very good to have that spirit to keep editing again.
So, what am I doing back here?[edit]
Having been "back" for over a year now to the point where this is the main phase of my editing time on Wikipedia, I just find the notion of writing on the subjects I like so appealing. Ever want to find out why the Sega 32X failed and what's really true amidst all of the internet rumors? I would say I have the answer now because of the research I put into writing its article, now a featured article. What was the real story behind Sega v. Accolade? The answer is now available to the public. It's so neat to me to do the research, find the right answers, and put them into a form which others can read and understand the whole story. That to me is just so enjoyable, and likely why I'm so focused on high quality contribution. Anymore I'm here because I enjoy it and I have time to enjoy it, which when combined with my job and my other writing projects I do, such as my fantasy fiction writing, makes me feel like quite the productive individual.
Despite it all, I'm still an administrator hopeful and would love to be renominated to have access to "the mop" after I've regained my experience with writing Wikipedia articles and with contributing in Wikipedia's service areas. I'd really like to have a focus on dispute resolution and the administrator's noticeboard, as I fancy myself a good mediator of discussion, but would love to help out in other areas such as XFD, etc. My only RFA failed because of my naivety, but with six years comes a sense of maturity and a knowing of what I was missing before, and what I needed to learn from the experience.
A brief rundown of my editing philosophies[edit]
Very much, I'm a true WikiDragon. I make huge edits to pages, often focusing on one or two at a time, striving to amp up its quality. I always shoot for good article status as a bare minimum on any project I work on. I do tend to be a little protective of my own edits, but I credit that to pride, a trait that I have both on and off the encyclopedia. The opportunity to improve an article that has been down for so long and to work on it on my own to make it worth reading is a very appealing aspect to editing that I believe allows me to enjoy contributing.
Areas of my editing interest[edit]
If you would like me to assist with an article that is in my interest area, feel free to leave a message on my talk page and I'd be glad to have a look.
- Video game consoles, especially for Sega
- Related video game franchises, such as Phantasy Star Online, Hyperdimension Neptunia, Sonic the Hedgehog, etc.
- Indiana State Roads and interstate highways. Seriously, though, INDOT needs to reconsider their road numbering in a few places...
- Legal cases related to video game law, such as Sega v. Accolade
I also periodically do some FA and GA reviewing on request.
My favorite contributions[edit]
Here's some of the articles and lists that contain my best contributions. Anything listed here, I have personally worked on to make it have that status. Former GAs were demoted during my inactive periods, as the referencing standards of Wikipedia have improved. Though I am disappointed in the diminished article qualities that have resulted, I am glad to know the standards have improved and look forward to the challenge of improving them again.
- Sega Genesis
- Sega Genesis
- Sega CD
- Sega 32X
- Master System
- Sega v. Accolade
- List of Sega Genesis games
- List of Sega CD games
- List of Sega 32X games
- Sonic X-treme
- Sega Saturn
- Sega Game Gear
- Sega Nomad
- Sega Pico
- Sega Channel
- Sega Meganet
- WonderSwan
- Indiana State Road 930
- U.S. Route 30 in Indiana
- Crush 40
- Jun Senoue
- Wave Master
- List of Sega video game franchises
- List of Sega arcade system boards
Current projects[edit]
Future projects[edit]
- Sega
- Sega Sammy Holdings
- Hyperdimension Neptunia - with an addendum that I'd like to work on the whole series and restructure it as a whole
- Phantasy Star Online
Feel free to navigate my userspace with the bottom box, and thanks for visiting. You can also leave comments for me here and I'll get back to you as soon as I'm on next.
Red Phoenix flame of life...protector of all...
- Wikipedia pending changes reviewers
- Wikipedia rollbackers
- Wikipedians open to trout slapping
- Male Wikipedians
- Wikipedians by alma mater: Indiana University-Purdue University Fort Wayne
- Wikipedians with Bachelor of Science degrees
- WikiProject Video games members
- WikiProject U.S. Roads/Indiana participants
- Wikipedians seeking to adopt in Adopt-a-user
- Wikipedia administrator hopefuls
- Wikipedia featured topic contributors
- Wikipedia featured article contributors
- Wikipedia featured list contributors
- Wikipedia Good Article contributors
- Million Award
- Wikipedians interested in chess
- User en-N
- User es-2


text:
MeeGo standard-bearer gets a lick of paint.
MeeGo marvel won't make it to Blighty.
Joe Mininahe wants Nokia to give the N9 the chance it deserves.
Official countdown timer vanishes from site.
MeeGo's debut dated.
All go for MeeGo.
Mixed messages coming out of Finland.
Could be a no go for MeeGo.
Meego a-go-go.
Meego makes its long-awaited handset debut on the N9.
Join our email list to get the inside line on the latest phones and money-saving offers. And we'll help you make informed buying decisions with handset reviews and consumer guides too.


text:
Sorry but this item is currently unavailable.
Please check back at a later stage.
*** Fabric is 100% cotton and will stretch, so we recommend ordering your natural size. ***
Large zinnias in shades of maize and ivory brighten up this dark grey background, bringing cheer into any environment. The Lemon Cello Scrub Hat looks great with our Pewter Scrubs and our Jet Black Scrubs.


text:
Daniel Goldowitz
Dan Goldowitz received his PhD in Psychobiology at the University of California at Irvine with a thesis that focused on the plasticity of the adult central nervous in response to lesions. His subsequent postdoctoral work at Harvard Children's Hospital in Boston, the Karolinska Institute in Stockholm, and the University of Utah School of Medicine in Salt Lake City was in the development of the nervous system. His first position was as an assistant professorship at Jefferson Medical School in Philadelphia. Using approaches that were relatively novel to the study of the brain he pioneered approaches to ascertain the function of genes in brain and behaviour. He moved to the University of Tennessee Health Science Centre (UTHSC) in Memphis and was a leading force in organizing researchers across the State of Tennessee in forming a collaborative to use the mouse as a model organism to identify the function of the genes that were just being uncovered with the human genome project. The Tennessee Mouse Genome Consortium was the result of these efforts and this collaborative won one of three US National Institute's of Health (NIH) awards (amounting to about US$13,000,000 over 5years with D. Goldowitz as the Principal Investigator) to understand the role of genes in the function of the brain. This success led the University of Tennessee system to create a US$6,000,000 in a program to fund a Centre of Excellence in Genomics and Bioinformatics proposed by Goldowitz. He also worked with other individuals at UTHSC to obtain NIH funding for projects to bring science education to the K-12 grades. He was awarded an endowed chair of Neurosciences at UTHSC. These efforts have resulted in national and international collaborations that Dan brought to Canada (the Centre for Molecular Medicine and Therapeutics at the Children and Family Research Inst at UBC). He currently holds a Tier 1 Canada Research Chair. He maintains strong NIH- , CIHR- and foundation-funded research programs in the genetics of brain development and function. After a bit more than one year in Canada the call for proposals from the Networks of Centres of Excellence (NCE) was published. A survey of the research landscape indicated that Canada had some incredible strength in brain development, both clinically and in the basic sciences, but that they were not united in a way that could bring a synergy that seemed possible. From this as a vantage point, and with a focus of creating a marriage between the clinical and basic sciences, Goldowitz led a successful application to be one of three new, federally funded NCEs, NeuroDevNet.
Thoughts on his research
Illness does not start with symptoms, it starts with a biological event that triggers the path to disease. For many illnesses that event happens long before birth.
Dr. Goldowitz studies how genetic signals involved in the early development of the nervous system can cause neurodegenerative disease and brain disorders in children and adults. By understanding how the brain develops and is built, he will also be able understand how brain disorders develop.
"I am interested in how to put the brain together," says Dr. Goldowitz. "By putting it together you come out with insights that you couldn't achieve any other way."
A major focus of his work is the application of molecular and bioinformatic technologies to study the entire gene regulatory network of the cerebellum, which is an area of the brain that is linked to autism, schizophrenia, mental retardation, and other brain disorders.
"For the first time in the mammalian nervous system we will be able to come up with a blueprint for how to make a part of the brain," explains Dr. Goldowitz.
And once he understands how to build it, researchers will be a lot closer to being able to fix it.
Scientific Director, NeuroDevNet (funded by Networks of Centres of Excellence) – 2009 ~ 2014, 2014 - 2019
President, International Behavioural and Neural Genetics Society – 2007
Canadian Research Council Chair in Developmental Neurogenetics – 2007 - 2014, 2014 - 2021


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RIDGID Faucet and Sink Installer Tool
- For close quarters plumbing under a sink
- Fits over existing supply lines
- Works on a wide number of basin nuts
- Model
- 27018
- Internet/Catalog:
- 100595073
- Store SKU:
- 149553
This RIDGID Faucet and Sink Installer Tool features an open slot for easy fit over existing supply lines (lines not included). The installer tool is constructed of lightweight high-strength plastic with durable aluminum inserts.
Info & Guides
- Lightweight high-strength plastic construction with durable aluminum inserts
- Open slot for easy fit over existing supply lines (lines not included)
- Use on 7/8 in. and 1 in. metal and plastic hex nuts (nuts not included)
- Notched ends to engage 2-, 3-, 4-, and 6-tab basin nuts (nuts not included)
- Extra long to turn hard-to-reach mounting nuts on faucets, sprayers and ball cocks (nuts, faucets, sprayers and ball cocks not included)
- Shutoff valve attachment turns hard-to-reach angle stops without marring chrome (angle stops not included)
- Holds strainer baskets in place (strainer baskets not included)
- Assembled Depth (in.) :
- 16.00 in
- Assembled Height (in.) :
- 3 in
- Assembled Width (in.) :
- 6 in
- Cutter size (in.) :
- 0
- Handle Length (in.) :
- 0
- Primary application :
- Tighteninig faucet nuts, sink strainer, turning stops
- Replacement washers included :
- No
- Returnable :
- 90-Day
- Specialty Plumbing Tool Type :
- Specialty Plumbing Wrench
Ratings & Reviews73% of customers recommend this product
- Faucet and sink installer tool
April 22, 2014
- Recommended Product
I'm not a professional plumber but do on occasion repair and replace my faucets. I've used this tool a number of times and each time has helped with those jobs. It does not do large nuts for kitchen faucets. If it did, I would have given it 5 stars but since this tool lacks this attribute, I give it a 4 star. It does most everything else but from what I've found is it does not tighten or loosen large nuts for kitchen faucets.
sbonm8 out of 8 people found this helpful
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Dowell, E. and Weitkamp, E. (2011) An exploration of the collaborative processes of making theatre inspired by science. Public Understanding of Science, 21 (7). pp. 891-901. ISSN 0963-6625 Available from: http://eprints.uwe.ac.uk/15406
This list was generated on Wed Feb 22 02:37:15 2017 GMT.


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|Nelly Thompson was a happy housewife who did not care much about anything but keeping her house and raising the kids. But there was one thought which deprived her of her sleep. She had once seen Terry, her son, in the shower, and his sizeable cock was her obsession. One evening she could not keep in her lust anymore and simply pulled Terry's pants off! At first she was anxious whether Terry would like her mature body, but the boy was so passionate:
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|Anthony Kowalski, a divorced teacher, loved his cute blonde daughter Amanda more than anyone in the world. Since her very childhood he enjoyed taking photos and filming her on camera. When she grew into a very beautiful teen girl, Anthony's shootings acquired a different taste. Sometimes he thought that it would have been great to film her naked, and one day he talked her into some naked posing, which led them to a totally hardcore incest scene:
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text:
Stuffed Peppers Italian Style
|Thin cut macaroni
|50 Gram
|1 Medium, chopped
|1 Clove (5 gm), crushed
|Cooking oil
|30 Milliliter
|Minced beef
|450 Gram
|10 Milliliter
|Tomato puree
|10 Milliliter
|Beef stock
|150 Milliliter
|Button mushrooms
|100 Gram, sliced
|Mixed herbs
|2 1⁄2 Milliliter
|Green peppers
|4 Large
Cook the macaroni in boiling salted water until tender.
Fry the onion and garlic lightly in the oil and add the beef.
Continue to fry for 2-3 minutes.
Stir in the flour, tomato puree, ketchup and beef stock Boil until thickened.
Add the mushrooms, herbs and drained macaroni.
Remove the stalk and cut a cap from the top of each pepper.
Remove the seeds.
Fill with beef mixture.
Stand in the Slo cooker.
Add 150ml (1/4 pt) slightly salted water.
Cook for the recommended time.
Recipe Summary
Rate It
Nutrition Rank
Nutrition Facts
Serving size: Complete recipe
Calories 1630 Calories from Fat 804
% Daily Value*
Total Fat 90 g138.6%
Saturated Fat 29 g145.1%
Trans Fat 3.4 g
Cholesterol 279 mg93%
Sodium 645.5 mg26.9%
Total Carbohydrates 105 g35.1%
Dietary Fiber 18.9 g75.8%
Sugars 30.4 g
Protein 110 g219.9%
Vitamin A 55.2% Vitamin C 998.5%
Calcium 21.2% Iron 84.1%
*Based on a 2000 Calorie diet


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Jason Cannon
February 22, 2013
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What is your prediction for new truck sales in 2017?
Navistar introduces new 12.4-liter engine
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Kenworth T680, T880 available with Dana Spicer D-Series lightweight steer axles
Peterbilt names top North American and medium-duty dealer
International snags NJPA contract
Rush Truck Center holding Amazon recruiting days


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Brother BU220CL Belt UnitLaser Printer Developer Units
Product Number: BRTBU220CL
In Stock - Hurry, only 153 left.
Estimated Delivery - 1 business day(s) - Tue 2/28 2 business days - Tue 2/28
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Product Details
Brother BU220CL Belt Unit - Belt unit is designed for use in HL3140CW digital color printer with wireless networking, HL3170CDW digital color printer with wireless networking and duplex, and MFC9130CW. The approximate yield is 50,000 A4 or letter-size, single-sided pages. Your printer will indicate when you need to replace it.View Product Specs
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Gordon Gough: Chief Executive of Enterprise Northern Ireland
Published 16/03/2009
Helping small business grow in a recession
How's business?
As a membership organisation our performance is closely aligned to the performance of our members. There is no doubt the recession is having an impact on confidence, however, our members are continuing to provide a range of training and consultancy services and our recession proofing services are in great demand. Enterprise NI, which represents the network of local enterprise agencies, is currently delivering contracts through its members on behalf of Invest NI, Department of Employment and the Special EU Programmes Body and so our "order book" is quite healthy, although the challenge is always to secure new contracts before current ones run out.
Any exciting projects in the pipeline?
We are always looking at innovative ways to improve the services we offer to our members and are looking at a number of joint-purchasing initiatives to tap into the buying power of the local enterprise agency network. We are also hoping to bring a major UK conference on business incubation to Belfast later this year; if successful, it would be the first time this conference has been held in Northern Ireland. Another exciting project planned for later this year is when I hope to arrange for the local enterprise agencies to host a study visit to Northern Ireland by representatives of the Iraq Basra Development Commission who are looking for ideas on business start up interventions for the post-conflict Iraq.
What are the long term prospects for your organisation?
All membership organisations must constantly review the services they offer to members. Enterprise NI is constantly refining its membership offering and is looking at ways to expand membership so in short, it's positive but challenging.
What are the biggest challenges facing your organisation?
The Review of Public Administration (RPA) will most likely result in "ownership" of small business interventions shifting from Invest NI to the new 11 "super" councils and is the single biggest strategic issue for us. This poses the question: "Who will be responsible for small business policy?" We cannot have a situation in 2011 where there is not a unified small business policy for the province. Enterprise NI is well positioned to provide a solution for government.
Could the Government help you to do business better?
The Executive continues to take whatever measures it can to help businesses through the current recession. The £45m package of assistance recently announced will provide a much needed boost. The cash freeze on non-domestic rates for 09/10 is also to be welcomed. Invest NI will soon launch its new Small Business Support programme and I hope the local enterprise agencies are well placed to play a major role in the delivery of this initiative throughout Northern Ireland. One thing which government could undoubtedly help with is the public sector procurement process; at the moment it is unbelievably slow. This has ramifications for social economy, not for profit organisations in terms of HR planning and cash flow.
Why would someone want to work for you?
Enterprise NI provides great exposure to a multitude of tasks and situations. Working in a membership organisation is also a great environment for networking and you get the opportunity to meet lots of important people — recently I was in No 11 Downing Street meeting the Chancellor of the Exchequer, Alistair Darling.
Your views on the economy, please.
In 2007 the UK's national debt was 36% of GDP; by 2011 it's projected to be 56%! Change on that scale is usually brought about only by a major catastrophe, like war! There needs to be a shift in resources from the public to the private sector. However, the large public sector would suggest that Northern Ireland will be impacted less by the current downturn than other regions of the UK. On the plus side, certain parts of the local economy will be assisted by the weak value of sterling.
The business climate — good or bad?
It's not all gloom and doom. For example, some of our local enterprise agencies have reported an increase in property enquiries and many more are seeing an increase in the number of people enquiring about starting their own businesses. Also, the Enterprise Northern Ireland Loan Fund for small businesses has never been more popular as small business owners seek to inject some short term capital into their businesses.
What ambitions do your have on a personal level?
Nothing too fancy; just to give 100% to my work and to hopefully "do unto others as I would have others do unto me!"
What do you do in your spare time?
I'm a big connoisseur of the French film genre (especially anything starring Juliette Binoche) and I like nothing better than relaxing while watching a movie. For exercise I do a lot of walking and swimming. I'm also a big football fan and locally, I support Glenavon.
Belfast Telegraph


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By GERRY DOCHERTY & JIM MACGREGOR The history of the First World War (1914–1918) is a deliberately concocted lie. Not the sacrifice, the heroism, the horrendous waste of life or the misery that followed. No, these were very real, but the truth of how it all began and how it was unnecessarily and deliberately prolonged beyond 1915 has been successfully covered up for a century. A carefully falsified history was created to conceal the fact that Britain, not Germany, was responsible for the … [Read more...]
The Secret Origins of the First World War
The Mystique of the Manor: Australia's Occult Centre Revealed
By PAUL YOUNG Pilgrims have been drawn to the other-worldly auras of hallowed sites, both natural and man-made, all around the globe since antiquity. One such sanctuary sits right in the heart of Sydney and, although it has slipped from prominence today, it played a significant role in Australia's spiritual and esoteric history. While its narrative has primarily been expressed through the descriptions of the characters who have occupied it, the magnetism of the building and the ground it … [Read more...]
Gallipoli: The Untold Story – 'The first casualty of war is truth'
By GERRY DOCHERTY & JIM MACGREGOR The truth about Gallipoli has, unlike its victims, been buried deep. Historians like Peter Hart who describe it as "an idiocy generated by muddled thinking"1 are justified in their anger, but not their conclusions. The campaign was conceived in London as a grotesque, Machiavellian strategy to fool the Russians into believing that Britain was attempting to capture Constantinople for them. The paradox of its failure lay in its success. Gallipoli was … [Read more...]
C.W. Leadbeater: Saint or Sinner?
By FRANK JOSEPH— Rare is the man or woman whose controversy in life outlives their death into the next century. But such were H.P. Blavatsky and C.W. Leadbeater, the founder and promoter, respectively, of Theosophy. Their legacy of notoriety and fame are generated less by the unorthodox, even heretical ideas they espoused with such unrepentant vigour during an era of Victorian sensibilities, than their outrageous personal behaviour which, even today, would have gotten them both into deep … [Read more...]
The Gympie Pyramid: Evidence of an Ancient Civilisation in Australia?
By GORDON DE L. MARSHALL— The Gympie Pyramid near the town of Gympie in Queensland, Australia has long been a source of fascination for people from around the world as well as Australia, and the subject of a great many claims about its origin and true purpose. (LEFT: Ancient statuette of the Indian goddess Lakshmi dug up near the Gympie Pyramid) Archaeologist Greg Jefferys, who has worked on the pyramid, refers to it as "a serious, famous and unexplained archaeological anomaly."1 … [Read more...]
The First Race: Out-of-Australia, Not Africa!
By STEVE STRONG Over the last decade, all manner of unexpected archaeological discoveries have led to many experts questioning much of what was assumed to be fact. Recent findings and field-work relating to little 'hobbits' in Flores Island, Siberian hominids with mtDNA connections to people of Papua New Guinea, the exclusivity of our distinct genetic Homo sapiens code being compromised by a 4% Neanderthal input, and a variety of unexpected findings have called into question many elemental … [Read more...]
Ancient Egyptians in Australia! Could Mysterious Engravings Rewrite our History?
By STEVE STRONG— Until receiving a phone call from Nina Angelo (OAM), I knew nothing of neither the struggles involved in protecting the land around Kariong (near Gosford) nor that part of this land was now on the market. When on-site I had seen a lot of tagged trees, and a for sale sign somewhere along a main road, but being unfamiliar with the whole region, nothing registered. The land for sale contains the Gosford Glyphs, located near Kariong, about 60 km north of Sydney. This site … [Read more...]
Did Chinese Mariners Land on Australian Shores Before Europeans?
BY DAN BYRNES — Gavin Menzies, the former British submariner, and author of 1421: The Year That China Discovered The World1 is visiting Warrnambool (located in the Australian state of Victoria) in September this year [2005] to test his startling theory against a resolution of the mystery of the Mahogany Ship. A fascinating contest between maritime mystery theories is now being proposed. Since he published, Menzies has maintained a website (www.1421.tv) to present evidence he believes … [Read more...]


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The Lost Treasure of the Knights Templar: Solving the Oak Island Mystery
Inner Traditions/Bear, Feb 1, 1999 - Social Science - 304 pages
A compelling argument that connects the lost treasure of the Knights Templar to the mysterious money pit on Oak Island, Nova Scotia, that has baffled treasure hunters for two centuries
• Fascinating occult detective work linking the Cathars, the Scottish Masons, and Renne-le-Chateau to the elusive treasure pit on Oak Island
• Draws on new evidence recently unearthed in Italy, France, and Scotland to provide a compelling solution to one of the world's most enduring mysteries
When the Order of Knights Templar was ruthlessly dissolved in 1307 by King Philip the Fair of France it possessed immense wealth and political power, yet none of the treasure the Templars amassed has ever been found. Their treasure is rumored to contain artifacts of spiritual significance retrieved by the order during the Crusades, including the genealogies of David and Jesus and documents that trace these bloodlines into the royal bloodlines of Merovingian France.
Placing a Scottish presence in the New World a century before Columbus, Steven Sora paints a credible scenario that has the Sinclair clan of Scotland transporting the wealth of the Templars--entrusted to them as the Masonic heirs of the order--to a remote island off the shores of present-day Nova Scotia. The mysterious money pit there is commonly believed to have been built before 1497 and has guarded its secret contents tenaciously despite two centuries of determined efforts to unearth it. All of these efforts (one even financed by American president Franklin Delano Roosevelt) have failed, thanks to an elaborate system of booby traps, false beaches, hidden drains, and other hazards of remarkable ingenuity and technological complexity.
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The Lost Treasure of the Knights Templar: Solving the Oak Island Mystery
Steven Sora
Limited preview - 1999


text:
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Date: 1893
Description: The log cabin of Len Thomas.
Date: 1951
Description: Interior view of the trading post at Willie's White Birch Lodge. Fishing lures are on display on the back wall behind a counter with signs that say: "Pat's...
Date: date unknown
Description: Photographic postcard from hill of White Sand Lake seen through trees. A raft with a diving platform is near the shoreline.
Date: 1920 ca.
Description: This early 20th century map shows the soil types in Vilas County, Wisconsin, and adjoining areas in Oneida, Forest, Iron, and Price counties. Also depicted...
Date: 1956 ca.
Description: Senator and Mrs. Joseph R. McCarthy at the Gateway Hotel in Land O'Lakes. A very similar image appeared on the McCarthy's 1956 Christmas card contained in...
Date: 1931 ca.
Description: Students work at their desks in the Mayo School, District No. 1. A row of books forms the foreground; history lessons from the time of reconstruction after...
Date: 1954
Description: The dining room at Syd's Resort of the Woods, which shows tables set for a meal. Large picture windows have views of the lake and woods surrounding the res...
Date: 1912 ca.
Description: Vilas County, Ricing camp, Rice Creek. Lac Du Flambeau area.
Description: Mr. Bearskin, a medicine man, at Lac du Flambeau seated in front of of a wigwam covered with elm bark. This image is part of an exhibit about Native Americ...
Description: Joe Mietus, 16, poses at the Mayo School, District No. 1. On the reverse of the photograph is written, "Has invented several home made farm tools. Also has...
Date: 1935 ca.
Description: Manitowish Lake in Manitowish Waters.
Description: View across water of the east shore of Trout Lake.
Date: 1936 ca.
Description: These two maps of the Town of Conover, Vilas County, Wisconsin, show private land holdings of a section or more as of 1927 and public lands in 1936. Acreag...
Date: 1911-05
Description: Trout Lake was the site of the first forest planting or nursery. This camp was at the north end of Trout Lake.
Date: 1900 ca.
Description: Exterior view of Sayner Resort on Plum Lake.
Description: Mr. Bearskin, a medicine man, at Lac du Flambeau, Wisconsin. This image is part of an exhibit about Native Americans prepared by Paul Vanderbilt, first cu...
Date: 1977-10
Description: Man harvesting cranberries on water.
Date: 1958
Description: View across water towards men, women, and children sitting in metal boats on a lake. They are watching five men standing waist deep in the lake holding up...
Date: 1939 ca.
Description: Interior view of Bob McGlinn's Dance Tavern showing the wooden dance floor with chairs and benches along the walls. In the back left corner is a stage. The...
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text:
› Womens Mini Skirts
› Made from 100%Polyester
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› Mini Skirt
› Colour: Multi
Size and Fit Info:
› Womens Mini Skirt
› Model's height 173cm (5'8")
› Model's bust 86cm (32")
› Model's waist is 64cm (25")
› Model is wearing a size 8
About Snake Bite:
Loud and proud apparel for the girl who lives for the night. Metallics, sequinning and sexy cuts Snake bite is rock and roll to the core while maintaining it's girly glitz and glam. Once bitten you'll be forever smitten.


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|Message view
|« Date » · « Thread »
|« Date » · « Thread »
|"Benjamin Wootton" <benwoot...@ftml.net>
|Multiple Consumers
|Thu, 25 May 2006 10:03:11 GMT
** Apologies if this came through yesterday. I sent it once but don't think it left my outbox! ** I'm new to messaging so forgive me if this is a silly question. I would like a number of in-process consumers subscribing to different topics. Whenever one of these topics ticks, I would like to callback to a Java method. What is the right idiom for doing this? Something like the following is fine in the scenario where we only have a single consumer: while ( ( message = consumer.receive( 10000 ) ) != null ) { processMessage( message ); } But clearly isn't what we need where we have multiple consumers. I've considered placing each consumer in it's own thread, but I'd like the callback to be called in a deterministic order (ie the same order that the message arrives in.) The semantics of the avaialble receive methods also don't seem to fit with doing this. new Thread() { public void run() { try { Message message; while ( ( message = consumer.receive( 1000000 ) ) != null ) { processMessage( message ); } } catch( Exception exception ) { exception.printStackTrace(); } } }.start(); Is there any example code around for this? Thanks in advance Ben -- Benjamin Wootton firstname.lastname@example.com
|View raw message


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The Laurels Guest House
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TripAdvisor Reviews The Laurels Guest House Blairgowrie
Travel Blogs from Blairgowrie
Day 3 -Second day in Edinburgh-
This morning we both woke around 5 am (after waking already at about 3am but managing to dose off again thank goodness) so we got ready pretty early and headed down to the hotel breakkie - "big scottish breakfast" it claimed-and we were looking forward to that after a bit of a disappointing dinner last night. But it too was a let down, oh well....we'll keep trying..... Warmish and fine today so we headed out and wandered ...
Last days in London, then was onto Turkey
... for all. COLD COLD COLD AND MORE COLD. We we frozen solid. The toilets were how should I say it... Feral. But you made do. Our Anzacs didn't have anywhere near what we had been provided so you sucked it up. The reflective program playing through out the night was a good touch. Learnt lots of things. Dawn approached, they lit up the waters and it looked stunning. Very eerie indeed but beautiful nonetheless. It's amazing to think what our Anzacs thought of it all way back ...
Starting the Sabbath in Blairgowrie
... great when that happens.
After a lazy lunch, meaning absolutely everyone in the family eating at a different time, my brother was finally ready to pack up his car and take me to visit Mum. The plan was to transfer me over to my other sister in the hospital parking lot at around 5pm on her way home from work.
This visit today, though, just didn't seem timed right. First of, Mum didn't look ready, and we ...
Final show
... expected. I on the other hand don't usually get too attached to any show. It's probably because I've been doing this too long. I get attached to people but I'm always very happy to move on to the next thing, in this case it's a mini trip to London and then finally New York! Paul celebrated the closing show with a pile of cupcakes for the cast and crew. They were pretty good. We left the theater to head back to my flat to return everything. Most everyone decided to go down the ...
Out of Africa
... it is so cute. People in full tweed suits need a high five. Its amazing. I only got the jacket but I will work on the rest!
My last evening in Edinburgh I shouted myself to an incredible meal with delicious bubbles and wine. And then I had a couple of whiskies just to make cammy proud and went to bed with the sound of bagpipes out my window. Scotland, you rock.
Now I am back at work and looking forward to my next break when mum and dad come over to take on Botswana and ...
Other places to stay in Blairgowrie
Heathpark HouseHeathpark House Coupar Angus Road, Blairgowrie | B&Bfrom $101
Drumellie MeadowDrumellie Meadow Drumellie Meadow, Blairgowrie | B&Bfrom $78
Ridgeway Bed and BreakfastWester Essendy, Blairgowrie | B&Bfrom $54


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Mystery Shopper Womens Hoodie
Stencil street art of mysterious person dressed as an astronaut carrying his or her shopping back from the shops. Possibly resupplying the International Space Station?
We print all Hoodies using the latest DTG print technology and highest quality inks to ensure a superior print quality and a lasting finish. The double fabric hood with self-coloured drawcord and a front kangaroo pouch pocket makes this Hoodie just perfect.
Shipping is £3.99 globally on orders less than £30. Shipping is FREE for all orders over £30. Orders are delivered within 5-7 business days. If you have a query about delivery for a product which you have already ordered, please contact us.
If you don't absolutely love it, we'll take it back!
If you're not happy with your order, please contact us as soon as possible. In all cases we'll ask you to provide photographs of the item, including a close up of any tags/labels. To help us respond to you quickly, please include the order number in your message to us.
We have a money-back satisfaction guarantee, so whatever the problem, we're happy to work with you to fix it.
- Tags: 7-eleven, 99p-stores, astronaut, automated-retail, bargain-booze, best-one, booker-group, budgens, camouflage, convenience-store, convenient-food-mart, cornershop, costcutter, disguise, general-store, helmet, ikea, kwik-save, londis, mace-store, mystery-shopping, nasa, other, personal-protective-equipment, poundland, poundworld, retail, shopping, space, space-invaders, stencil


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With the first episode of 'Into the Light', we gave you three clues: the route is big, unique, and has never been done before and likely will never be done again.
Before beginning the big project, Glowacz and Sharma go for a difficult, over-hanging deep-water solo. More than just a climbing pool party, it was a chance for the two climbers to get to know each other as they prepare to climb as partners, in an environment that's incredibly challening, but also low-risk. "It's the most playful form of solo climbing," says Glowacz, who, by our count, fell into the water at least four times (and that's just what made the video.)
With some trainign and prep out of the way, the big project looms. Stay tuned!


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CGNEE Invtied to BFA Financial Cooperation Conference in London
BFA (Boao Forum for Asia) Financial Cooperation Conference is held in London from November 8th to 11th, 2015. It is […]
Bailu Cup Tennis Invitational held Successfully in France
China General Nuclear Power Group Europe Energy (hereinafter refferred to as CGNEE) hosted the 3rd Bailu Cup Tennis Invitational in […]
Project Acquisition: Clover
EDF Energy Renewables sells stake in three UK wind farms to CGN Following a competitive auction process, EDF Energy Renewables, […]
Lastest News
CGNEE Participated in the 2016 Footeolien Tournament with French Peers
CGNEE was pleased to participate in the "Footeolien#2016" tournament organized by France Énergie Éolienne (FEE). As a new member of FEE, this year was…Shenzhen General Chamber of Commerce established a Representative Office in France
Recently, China Shenzhen General Chamber of Commerce (SGCC) Representative Office in France is formally established, the CEO of CGNEE, Mr. LU Wei, is appointed General…Mr. LU Wei met with Air France CEO Frédéric Gagey
On 21st March 2016, the CEO of CGNEE Mr. LU Wei met with the CEO of Air France Mr. Frédéric Gagey and the Senior Vice…MEMORANDUM OF UNDERSTANDING SIGNED WITH EDF ENERGIES NOUVELLES AND INNOSUN
On December 4th, at the occasion of the Climate Conference in Paris (COP21), CGN Europe Energy, EDF ENERGIES NOUVELLES (EDFEN) and InnoSun signed a three-party…Memorandum of Understanding signed with China Merchants New Energy Group and Huawei Technologies
On December 3rd, during the "creating green sustainable cities" day of Paris Climate Change Conference(COP 21), CGN Europe Energy, China Merchants New Energy Group and Huawei…Shenzhen General Chamber of Commerce (SGCC) Delegation visited CGN Europe Energy
On November 30th, at the occasion of "China Pavilion Enterprise Day" of Paris Climate Change Conference 2015 (COP21), Mr. WANG Shi, Chairman of Shenzhen General…CGNEE Signing A Joint Development Agreement on Distributed Solar Power Plants in France
CGNEE is pleased to announce that a joint development agreement has been signed between us and Inovia Concept Development (ICD) in Paris, France on November…
On June 30th, 2014, China General Nuclear Power Corporation – Europe Energy was registered in France. CGNEE is a wholly owned subsidiary of China General Nuclear Power Corporation, and its business mainly focuses on the investment and acquisition, development and construction, and asset management of renewable energy projects in Europe, such as off-shore wind power, on-shore wind power and photovoltaic power.


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How to Host a State Dinner at Home
We tracked down the three wines served at last night's White House state dinner so that you can host your own version tonight.
At last night's state dinner for French President Francoise Hollande, guests drank three American wines made by French-born winemakers:
Morlet Family Vineyards "La Proportion Dorée" 2011 ($80)
Chester Kidder 2009 ($37)
Thibault-Janisson Blanc de Chardonnay ($25)
We wondered if the wines were available for sale at local wine shops. We found 10 bottles of the Chester Kidder for sale at The Corkscrew in Springfield, IL (Obama's home state—or at least the state where he owns a home!). Mister Wright Fine Wines & Spirits, on NYC's Upper East Side, has 12 bottles of Morlet Family Vineyards's "La Proportion Dorée." And MacArthur Beverages, in Washington, DC, has two cases ready for purchase.
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À votre santé!
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COGA hosts an annual half-day training for small operators each fall that is focused on providing skills for better community engagement, information on the state of the industry, and regulatory and compliance updates from state agencies.
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COGA supports low-income household energy assistancePosted | Videos
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Health Study Must be ScrutinizedPosted | Health & Safety | Hydraulic Fracturing | Oil and Natural Gas | Resources
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Mardi Gras Ball – Sold Out!March 3, 20176:30 pm
COGA Connect LuncheonMarch 21, 201711:30 am
Lunch and Learn: University of Wyoming Energy Management MBA programMarch 23, 201711:30 am
Quiz Night with COGAApril 3, 20174:00 pm


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Price per Night Range
Bedrooms (min)
Sleeps (min)
1 Lourmarin Pet Friendly Vacation Rentals were found matching your criteria.
3 Bedroom, 1 Bathroom, Sleeps 6
Lourmarin, Provence-Alpes-Cote D'Azur, France
Description: Cucuron 8 km from Lourmarin: Single-family house "Les Thyms". In a secluded position. Private: property 3'000 m2 (fenced), natural garden. In the h...
$143 - $238 /night
$1001 - $1666 /week
This map is intended to be used as a reference only.
Available Unavailable Night Min.


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Hotfrog NewZealand provides information regarding The Bearing Point Restaurant & Bar in Ohakune Manawatu-Wanganui. The Bearing Point Restaurant & Bar is located at 55 Clyde Street, Ohakune Manawatu-Wanganui 4625 and provides Food and Dining services. Contact them on 06-385 9006.
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27 Ayr Street Ohakune Manawatu-Wanganui 4625
PO Box 201 Ohakune Manawatu-Wanganui 4625
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4 Moore Street Ohakune Manawatu-Wanganui 4625
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