text:
Over ttie past 2 decades, advances in mouse molecular genetics tiave lead to significant discoveries in neural function and development, findings that simply are not attainable without these valuable animal resources. The widespread use of genetically engineered mice has resulted in a huge array of available altered strains, which are shared widely among the research community. Additionally, the technology for generating genetically altered mice has continued to improve, and has become a conventional tool for manipulation of candidate genes. Importantly, conditional mouse genetic lines are now readily available that allow temporal and tissue specific manipulation of genes, either transiently, or indelibly. Researchers in the RMTSC employ mouse lines representing each of these aspects of cutting edge mouse molecular genetics, and in doing so, are advancing the field significantly. The primary function of Core A is to support RMTSC researcher use of mice, by maintaining breeding stocks of genetically altered mice, assisting in developing complex breeding strategies to produce offspring with the correct engineered alleles for genetic experiments, providing highly efficient genotyping of offspring, and imparting concise technical advice in the design of constructs for the genesis of new mouse lines. Given the success of our Core A in supporting mouse work through these services to RMTSC researchers in the past 9 years, the 3 overarching aims of this Core proposal remain unchanged from those ofthe previous submission.
Aim 1. To maintain genetically altered mice.
Aim 2. To genotype offspring of genetically altered mice..
Aim 3. To advise investigators in designing constructs for generation of genetically altered mice.
|Hansen, Anne; Ghosal, Ratna; Caprio, John et al. (2014) Anatomical and physiological studies of bigheaded carps demonstrate that the epibranchial organ functions as a pharyngeal taste organ. J Exp Biol 217:3945-54
|Ganchrow, Donald; Ganchrow, Judith R; Cicchini, Vanessa et al. (2014) Nucleus of the solitary tract in the C57BL/6J mouse: Subnuclear parcellation, chorda tympani nerve projections, and brainstem connections. J Comp Neurol 522:1565-96
|Nunez-Parra, Alexia; Li, Anan; Restrepo, Diego (2014) Coding odor identity and odor value in awake rodents. Prog Brain Res 208:205-22
|Rorabaugh, Jacki M; Stratford, Jennifer M; Zahniser, Nancy R (2014) A relationship between reduced nucleus accumbens shell and enhanced lateral hypothalamic orexin neuronal activation in long-term fructose bingeing behavior. PLoS One 9:e95019
|Sclafani, Anthony; Ackroff, Karen (2014) Maltodextrin and fat preference deficits in "taste-blind" P2X2/P2X3 knockout mice. Chem Senses 39:507-14
|Castillo, David; Seidel, Kerstin; Salcedo, Ernesto et al. (2014) Induction of ectopic taste buds by SHH reveals the competency and plasticity of adult lingual epithelium. Development 141:2993-3002
|Saunders, Cecil J; Christensen, Michael; Finger, Thomas E et al. (2014) Cholinergic neurotransmission links solitary chemosensory cells to nasal inflammation. Proc Natl Acad Sci U S A 111:6075-80
|Stratford, Jennifer M; Thompson, John A (2014) Beta-galactosidase staining in the nucleus of the solitary tract of Fos-Tau-LacZ mice is unaffected by monosodium glutamate taste stimulation. PLoS One 9:e107238
|Frenz, Christopher T; Hansen, Anne; Dupuis, Nicholas D et al. (2014) NaV1.5 sodium channel window currents contribute to spontaneous firing in olfactory sensory neurons. J Neurophysiol 112:1091-104
|Sheridan, D C; Hughes, A R; Erdélyi, F et al. (2014) Matching of feedback inhibition with excitation ensures fidelity of information flow in the anterior piriform cortex. Neuroscience 275:519-30
Showing the most recent 10 out of 106 publications


text:
notes Stories May 13, 2016
notes Stories March 21, 2016
OS X 10.11.4 is now available, Mac gains Live Photos on Messages + secure Notes & more; iTunes 12.3.3 out as well
Apple has officially released the OS X 10.11.4 El Capitan update through the Mac App Store. The software update is available for all Macs capable of running OS X 10.11. The Mac update delivers new features including Live Photo viewing and sharing through iMessage using the Messages app as well as secure password support for individual notes in the Notes app.
Apple releases iOS 9.3 for iPhone, iPad and iPod touch featuring Night Shift, Touch ID Notes and more — here are all the new features
Following a lengthy beta period, Apple has now released iOS 9.3 for iPhone, iPad and iPod touch. iOS 9.3 is a significant feature update for Apple's mobile operating system, with brand new additions like Night Shift, Touch ID Notes and more. iOS 9.3 runs on every iOS 9-capable device, including the brand new iPhone SE. The update appears to weigh in at a hefty 1.7 gigabytes.
See our full walkthrough of all the new iOS 9.3 features after the break …
notes Stories February 22, 2016
Apple has released the fourth OS X 10.11.4 preview for registered developers to test ahead of its expected release next month. The software update to the Mac will likely be released around next month's March 15th event and is expected to coincide with a new version of iTunes. For Mac users, the latest version of OS X El Capitan adds enhancements like being able to view and share Live Photos originally taken on the iPhone 6s or 6s Plus as well as the ability to lock notes behind a secure password. We're check out the latest beta and update with any changes.
Apple has released the fourth iOS 9.3 beta for developers to test on iPhone, iPad, and iPod touch. The first iOS 9.3 beta appeared in early January. Apple is expected to release the iOS 9.3 software update to all users around next month's iPhone 5se/iPad Air 3 event. We'll check out the latest beta version of the upcoming release and highlight any changes below.
notes Stories February 10, 2016
Apple has released the third OS X 10.11.4 public beta for non-developer testers. Public beta testers running the El Capitan pre-release can find the new software update through the Mac App Store. The latest public beta update follows the third developer beta of the same update earlier this week. Apple has also released a second OS X 10.11.4 beta 3 build (15E39c to 15E39d) for developers as well.

subset: commoncrawl


text:
Welcome to Orchard Park Community Council
Orchard Park Community Council came into being on 1 April 2009 although the elections to the Council took place later, in June 2009. The most recent election was in May 2015 and the next elections are due to be in May 2019, apart from any election which may be called for a casual vacancy.
A 'Community Council' is another name for a Parish Council – the first level of government closest to the people and representing the concerns of the local community.
The council meets on the second Wednesday of each month at 7pm at The Orchard Community Centre. Everyone is welcome to attend any meeting with the opportunity to ask questions at the start of each meeting.


text:
Asparagus and Cheese Dip
|Asparagus spears
|12 (Fresh / Frozen)
|Danish blue cheese
|1 Ounce (25 Grams)
|Mustard powder
|1⁄2 Teaspoon (Leveled)
|1 Teaspoon (Leveled), chopped
|Wine vinegar
|15 Milliliter (1 Tablespoon (Leveled))
|Natural yogurt
|5 Ounce (150 Grams)
1. In a saucepan of boiling seasoned water; plunge asparagus spears until the base is tender.
2. Let asparagus cool down completely.
3. In a medium bowl, crush blue cheese and mix with mustard and chives.
4. Drizzle vinegar just to moisten the mixture.
5. Add yogurt and mix well.
6. Refrigerate dressing until chill.
7. In a plate, place asparagus tips and pour dressing on top.
Recipe Summary
Rate It
Nutrition Rank
Nutrition Facts
Serving size
Calories 122 Calories from Fat 58
% Daily Value*
Total Fat 7 g10.2%
Saturated Fat 4.1 g20.7%
Trans Fat 0 g
Cholesterol 19.8 mg6.6%
Sodium 515.5 mg21.5%
Total Carbohydrates 7 g2.4%
Dietary Fiber 0.94 g3.8%
Sugars 5 g
Protein 7 g14.6%
Vitamin A 20.7% Vitamin C 7.4%
Calcium 21.4% Iron 10%
*Based on a 2000 Calorie diet


text:
Cardiac ischemia in patients with septic shock randomized to vasopressin or norepinephrine
- Sangeeta Mehta1Email author,
- John Granton2,
- Anthony C Gordon3,
- Deborah J Cook4,
- Stephen Lapinsky1,
- Gary Newton5,
- Kris Bandayrel1,
- Anjuli Little1,
- Chuin Siau6,
- Dieter Ayers7,
- Joel Singer7,
- Terry CK Lee7,
- Keith R Walley8,
- Michelle Storms8,
- D James Cooper9,
- Cheryl L Holmes10,
- Paul Hebert11,
- Jeffrey Presneill12,
- James A Russell8 and
- for the Vasopressin and Septic Shock Trial (VASST) Investigators
DOI: 10.1186/cc12789
© Mehta et al.; licensee BioMed Central Ltd. 2013
Received: 20 December 2012
Accepted: 20 June 2013
Published: 20 June 2013
Cardiac troponins are sensitive and specific biomarkers of myocardial necrosis. We evaluated troponin, CK, and ECG abnormalities in patients with septic shock and compared the effect of vasopressin (VP) versus norepinephrine (NE) on troponin, CK, and ECGs.
This was a prospective substudy of a randomized trial. Adults with septic shock randomly received, blinded, a low-dose infusion of VP (0.01 to 0.03 U/min) or NE (5 to 15 μg/min) in addition to open-label vasopressors, titrated to maintain a mean blood pressure of 65 to 75 mm Hg. Troponin I/T, CK, and CK-MB were measured, and 12-lead ECGs were recorded before study drug, and 6 hours, 2 days, and 4 days after study-drug initiation. Two physician readers, blinded to patient data and drug, independently interpreted ECGs.
We enrolled 121 patients (median age, 63.9 years (interquartile range (IQR), 51.1 to 75.3), mean APACHE II 28.6 (SD 7.7)): 65 in the VP group and 56 in the NE group. At the four time points, 26%, 36%, 32%, and 21% of patients had troponin elevations, respectively. Baseline characteristics and outcomes were similar between patients with positive versus negative troponin levels. Troponin and CK levels and rates of ischemic ECG changes were similar in the VP and the NE groups. In multivariable analysis, only APACHE II was associated with 28-day mortality (OR, 1.07; 95% CI, 1.01 to 1.14; P = 0.033).
Troponin elevation is common in adults with septic shock. We observed no significant differences in troponin, CK, and ECGs in patients treated with vasopressin and norepinephrine. Troponin elevation was not an independent predictor of mortality.
Trial registration
Controlled-trials.com ISRCTN94845869
KeywordsSeptic shock myocardial ischemia vasopressin norepinephrine troponin electrocardiogram
Cardiac ischemia occurs frequently in critically ill patients and is associated with increased mortality [1]. Given that most critically ill patients cannot communicate symptoms, the diagnosis of cardiac ischemia can be challenging and necessitates that clinicians rely on cardiac biomarkers and electrocardiograms (ECGs). Patients receiving vasopressors may be at even higher risk of cardiac ischemia than other patients because of coronary artery vasoconstriction, increased systemic vasoconstriction-induced afterload [2], or catecholamine-driven increases in myocardial oxygen demand.
The Vasopressin in Severe Sepsis Trial (VASST) randomized patients with septic shock to vasopressin or norepinephrine [3]. Overall, no significant difference occurred in the primary outcome (28-day mortality) between the vasopressin and the norepinephrine groups (35.4% versus 39.3%, respectively; P = 0.26). Further, no differences were found in the clinical diagnosis of myocardial infarction/ischemia in the two groups (2.0% versus 1.8%; P = 1.0), or in the incidence of cardiac arrest, tachyarrhythmias, or bradyarrhythmias. Vasopressin and norepinephrine are both potent vasoconstrictors, and animal studies suggest that vasopressin is associated with coronary vasoconstriction and myocardial depression [4, 5]. Therefore, we conducted a prospective study to examine, in more detail, ischemic ECG changes, troponin and creatine kinase (CK) levels, and clinical outcomes in a subset of patients enrolled in the VASST Trial. Our specific objectives were to describe troponin and CK levels and ECG abnormalities in patients with severe septic shock and to compare the effect of vasopressin versus that of norepinephrine on troponin and CK levels, ECGs, and the clinical diagnosis of acute myocardial infarction.
Materials and methods
Study design
This study evaluating the incidence of cardiac ischemia was a prospective observational substudy performed as part of the Vasopressin And Septic Shock Trial (VASST), a double-blind randomized controlled trial of vasopressin versus norepinephrine in patients with septic shock [3]. We previously published an article assessing intra- and interrater agreement of electrocardiogram interpretation in these patients [6]. VASST enrollment occurred between July 2001 and April 2006. This investigator-initiated substudy started after enrollment in the VASST Trial had begun, and thus was not included in the trial registration (ISRCTN94845869). Nine Canadian sites participated in this substudy, after obtaining local institutional research ethics board approval (St. Paul's Hospital, Vancouver General Hospital, Richmond General Hospital, University Health Network - Toronto General Hospital, University Health Network - Toronto Western Hospital, Mount Sinai Hospital, St. Michael's Hospital, St. Joseph's Hospital, Hotel Dieu Grace Hospital; see Additional file for locations). Written informed consent was obtained from all patients or their surrogates.
All patients enrolled in VASST in nine participating centers were included in this substudy. Patients were older than 16 years and had septic shock, defined by the presence of two or more of the systemic inflammatory response syndrome (SIRS) criteria, proven or suspected infection, new dysfunction of at least one organ, and hypotension, despite adequate fluid resuscitation requiring vasopressor support of at least 5 μg/min of norepinephrine (or equivalent) for 6 hours. More-severe septic shock was defined as treatment with 15 μg or more of norepinephrine or the equivalent per minute. Specific cardiac exclusion criteria of VASST were: unstable coronary syndrome (acute myocardial infarction during this episode of shock, based on the combination of history, ECG, and enzyme changes, as defined by the investigator), and underlying chronic heart disease (NYHA class III or IV). Patients were randomized to receive a blinded infusion of study drug, either vasopressin (0.01 to 0.03 U/min) or norepinephrine (5 to 15 µg/min). The study drug and all other vasopressors were titrated and weaned according to protocols, with an initial target mean arterial pressure of 65 to 75 mm Hg. Study-drug infusions were stopped if a serious adverse event was thought to be directly related to study-drug infusion.
Twelve-lead ECG recording and interpretation
The 12-lead ECGs were recorded at baseline (before study-drug infusion), and 6 hours, 2 days, and 4 days after initiation of the study drug, yielding a total of 373 ECGs. ECGs were read by two reviewers who were blinded to randomization group and troponin levels, by using a checklist to standardize the interpretation. Before the ECG interpretation, a calibration exercise was performed by the two reviewers to refine definitions and maximize interobserver agreement: this exercise and the checklist were previously published [4]. Each ECG was analyzed for rhythm and the presence of Q waves, ST elevation, ST depression, and T-wave inversion. Additionally, the readers assessed whether the ECG was normal or abnormal, and whether, in their opinion, the ECG changes represented ischemia.
Serum cardiac markers
Troponin I and T interpretation
Troponin I (µg/L)
Troponin T (µg/L)
≤0.5, No myocardial injury
<0.05, normal
Weakly positive
0.6 to 2.3, suggestive of myocardial injury
0.05 to 0.09, borderline
0.10 to 0.49, weakly positive
Highly positive
>2.3, suggestive of acute myocardial infarction
>0.49, positive
Ischemia based on ECG
Patients were categorized as having no ischemia, possible ischemia, or probable ischemia, based on ECG interpretations. Patients categorized as having no ischemia were those for whom both readers agreed on the absence of ischemic changes on all of their ECGs. Patients categorized as having probable ischemia were those for whom both readers agreed on the presence of ischemic changes on any single ECG. The remainder of patients were categorized as having possible ischemia, defined as the presence of ischemia on any ECG, without agreement between the two readers. In addition, at each site, using all available clinical data, including troponin levels, the local investigator independently assessed in real time whether the patient met criteria for acute myocardial infarction.
Statistical analysis
Continuous data are reported as mean and SD, or median and interquartile range (IQR) when not normally distributed. Binary data are reported as counts and proportions. Categoric variables were compared by using the Fisher Exact test, and continuous variables were compared by using the Wilcoxon rank-sum test. Linear and logistic mixed-effects models were used to assess the differences between treatment groups across times, assuming no time trends were present. In logistic regression, we examined factors associated with 28-day mortality in univariate and then in multivariate analysis. Candidate-independent variables were patient age, APACHE II score, more severe shock (defined as treatment with ≥15 μg/min of norepinephrine or the equivalent), history of diabetes, history of ischemic heart disease, vasopressin versus norepinephrine infusion, possible or probable ECG evidence of ischemia, and troponin elevation. Calculations were performed by using R Version 2.8.1 (R Foundation for Statistical Computing, Vienna, Austria).
Characteristics of patients in the troponin substudy
(n= 65)
(n= 56)
Age, years
62.9 (51.2, 73.6)
65.5 (50.8, 76.1)
Male sex, n (%)
43 (66)
42 (75)
Surgical patient, n (%)
25 (39)
25 (45)
28.1 (8.0)
29.2 (7.3)
Preexisting conditions, n (%)
Ischemic heart disease
Chronic obstructive pulmonary disease
Chronic renal failure
Liver disease
Solid-organ transplant
Corticosteroid use
Recent trauma
9 (14)
6 (9)
8 (12)
13 (20)
12 (18)
17 (26)
4 (6)
9 (14)
1 (2)
8 (14)
11 (20)
9 (16)
13 (23)
9 (16)
13 (23)
5 (9)
8 (14)
3 (5)
New organ failure at randomization, n (%)
65 (100)
58 (89)
43 (66)
20 (31)
21 (32)
56 (100)
50 (89)
41 (73)
13 (23)
18 (32)
Number of organ dysfunctions at randomization
3.0 (2.0, 3.0)
3.0 (2.0, 4.0)
Source of infection, n (%)
28 (43)
19 (29)
18 (28)
28 (50)
16 (29)
12 (21)
Hemodynamic variables at randomization
Systolic blood pressure (mm Hg)
Mean arterial pressure (mm Hg)
Arterial pH
Serum lactate (mM)
110.0 (98.0, 118.0)
72.0 (67.0, 77.0)
7.34 (7.3, 7.4)
2.3 (1.5, 3.6)
105.0 (95.0, 114.0)
70.0 (65.0, 75.0)
7.36 (7.3, 7.4)
2.2 (1.6, 4.1)
Vasoactive drug dosages at randomization
Norepinephrine (μg/min)
Epinephrine (μg/min)
Dopamine (μg/kg/min)
Dobutamine (μg/kg/min)
Phenylephrine (μg/min)
14.9 (9.1, 26.6)
30.0 (30.0, 30.0)
3.1 (3.0, 6.0)
6.3 (2.5, 12.5)
66.5 (31.1, 133.2)
18.1 (10.6, 30.0)
25.2 (8.4, 42.0)
8.2 (4.0, 17.0)
7.5 (2.5, 10.0)
104.7 (43.0, 134.5)
Days alive free of mechanical ventilation (first 28 days)
0.5 (0.0, 17.0)
1.0 (0.0, 16.0)
ICU stay,b days
11.5 (6.0, 26.0)
13.0 (6.0, 12.0)
Hospital stay,b days
26.5 (10.5, 74.0)
37.5 (18.5, 89.5)
28-day mortality,c n (%)
27 (42)
24 (43)
90-day mortality,c n (%)
31 (48)
32 (57)
Mean arterial blood pressure (MAP) was similar in the two treatment groups throughout the study, whereas the heart rate was significantly lower in the vasopressin group than in the norepinephrine group during the first 4 days of treatment (P = 0.033) (see Figure 1, Additional file). The rate of norepinephrine infusion was significantly lower in the vasopressin group than in the norepinephrine group during the first 4 days (P = 0.004) (see Figure 2, Additional file). No statistically significant differences were found in serum creatinine between the norepinephrine and vasopressin groups (Figure 3, Additional file).
Troponin, CK, and CK-MB levels
Baseline characteristics and outcomes of patients with and without elevations in serum troponin
Troponin levels (N= 120)a
(n = 72)
Weakly positiveb
(n = 30)
Highly positiveb
(n = 18)
P value
Age, years
62.7 (51.1, 72.6)
68.4 (47.8, 77.8)
63.2 (50.0, 73.4)
Male, n (%)
51 (71)
22 (73)
12 (67)
Surgical patient, n (%)
34 (47)
8 (27)
7 (39)
27.5 (7.6)
29.7 (6.6)
31.7 (8.6)
Preexisting conditions, n (%)
Ischemic heart disease
6 (8)
8 (27)
3 (17)
14 (19)
9 (30)
3 (17)
Corticosteroid use
8 (11)
7 (23)
2 (11)
New organ failure at randomization, n (%)
66 (92)
25 (83)
16 (89)
49 (68)
21 (70)
14 (78)
17 (24)
8 (27)
7 (39)
20 (28)
14 (47)
5 (28)
Clinical MI,c n (%)
0 (0)
2 (7)
3 (17)
28-day mortality,d n (%)
30 (42)
12 (41)
8 (44)
90-day mortality,d n (%)
40 (56)
14 (48)
8 (44)
Troponin, CK, and CK-MB levels at each time point in patients randomized to vasopressin or norepinephrine
Vasopressin group
median (1st, 3rd quartile), n
Norepinephrine group
median (1st, 3rd quartile), n
6 hours
Day 2
Day 4
6 hours
Day 2
Day 4
P value
Troponin I (µg/L)
(0.0, 0.54)
(0.0, 0.71)
(0.0, 0.60)
(0.0, 0.24)
(0.0, 0.39)
(0.0, 0.60)
(0.0, 0.43)
Troponin T
(0.02, 0.09)
(0.0, 0.14)
(0.0, 0.09)
(0.0, 0.02)
(0.0, 0.42)
(0.0, 0.38)
(0.01, 0.35)
(0.01, 0.39)
(61, 487)
(54, 435)
(36, 452)
(21, 189)
(60, 309)
(68, 438)
(41, 296)
(21, 222)
(1.6, 6.9)
(1.3, 6.0)
(1.0, 16.0)
(0.0, 3.1)
(1.0, 8.0)
(1.8, 17.2)
(2.0, 16.0)
(1.0, 6.0)
Electrocardiograms and ischemia
ECG interpretation at each time point in patients randomized to vasopressin or norepinephrine (N = 121)
Vasopressin (n= 65)
Norepinephrine (n= 56)
P value
Variable, n (%)
Baseline ( n = 61)
6 hours ( n = 43)
Day 2 ( n = 44)
Day 4 ( n = 39)
Baseline ( n = 54)
6 hours ( n = 40)
Day 2 ( n = 48)
Day 4 ( n = 35)
19 (31)
15 (35)
14 (32)
19 (49)
10 (19)
12 (30)
14 (29)
8 (23)
9 (15)
6 (14)
8 (18)
3 (8)
9 (17)
2 (5)
3 (6)
3 (9)
Atrial fib/ flutter/PSVT
6 (10)
10 (23)
7 (16)
4 (10)
15 (28)
13 (33)
14 (29)
8 (23)
Bundle branch block
6 (10)
4 (10)
6 (14)
4 (10)
7 (13)
4 (10)
7 (15)
7 (20)
ST elevation
6 (10)
4 (10)
3 (7)
2 (5)
4 (7)
3 (8)
3 (6)
1 (3)
ST depression
5 (9)
4 (10)
6 (14)
1 (3)
8 (15)
2 (5)
2 (4)
3 (9)
T inversion
10 (16)
10 (23)
8 (18)
6 (15)
12 (22)
8 (20)
11 (23)
8 (23)
Q wave
11 (18)
3 (7)
6 (14)
7 (18)
12 (22)
8 (20)
10 (21)
9 (26)
Ventricular rhythm
0 (0)
0 (0)
0 (0)
0 (0)
1 (2)
0 (0)
1 (2)
0 (0)
6 (10)
10 (23)
7 (16)
4 (10)
16 (30)
13 (33)
15 (31)
8 (23)
Comparison of patients with ischemia versus no ischemia on ECG.
No ischemiaa (N = 60)
P value
Age, years
64.1 (48.0, 77.1)
63.0 (53.5, 73.3)
Male, n (%)
40 (71)
41 (68)
Surgical patient, n (%)
21 (38)
25 (42)
29.9 (7.5)
27.4 (8.0)
Preexisting conditions, n (%)
Ischemic heart disease
10 (18)
4 (7)
13 (23)
10 (17)
Baseline lactate
2.0 (1.6, 4.5)
2.6 (1.5, 3.9)
More-severe shock,b n (%)
28 (50)
33 (55)
Vasopressin, n (%)
31 (55)
32 (53)
Days alive free of mechanical ventilation (first 28 days)
0.0 (0.0, 13.0)
2.0 (0.0, 17.0)
ICU stay,c days
13.0 (6.0, 31.0)
11.5 (6.0, 20.0)
Hospital stay,c days
27.0 (11.0, 77.0)
35.5 (16.0, 77.5)
28-day mortality,d n (%)
26 (47)
22 (37)
90-day mortality,d n (%)
33 (60)
47% to 73%
27 (45)
32% to 58%
Logistic regression
In the univariable analysis, only age (OR, 1.03; 95% CI, 1.00 to 1.05; P = 0.028), APACHE II (OR, 1.08; 95% CI, 1.02 to 1.14; P = 0.005) and the presence of more-severe shock (OR, 2.32; 95% CI, 1.11 to 4.88; P = 0.025) were associated with 28-day mortality. In the multivariable analysis, only APACHE II score (OR, 1.07; 95% CI, 1.01 to 1.14; P = 0.033) was highly associated with 28-day mortality.
Sensitivity analyses
ECGs and troponin assays were not performed for some patients at some of the time points. Such missing data may result in an overestimate of abnormalities we observed, given that patients for whom clinicians recorded ECGs and troponin levels have a greater likelihood of being labeled abnormal. We thus repeated our analyses in two different ways. First, we used only baseline ECG reading and troponin level as predictors. In a second analysis, we used the ECG reading and troponin level as time-dependent covariates. Our overall results did not change in either analysis.
Regarding our first objective, in this prospective substudy of patients who had septic shock enrolled in VASST, troponin elevations were very common, occurring in up to 36% of patients. However, troponin elevation in patients with septic shock was not associated with increased mortality, compared with patients with no troponin elevation. Cardiac ischemia on ECGs was also common, occurring in 48% of patients at one or more of the measured time points; however, cardiac ischemia on ECG was not predictive of worse outcomes.
Regarding our second objective, no significant differences were found in troponin and creatine kinase levels between vasopressin- and norepinephrine-treated patients. In addition, the overall incidence of ECG cardiac ischemia was similar in the vasopressin- and norepinephrine-treated patients, although more patients in the norepinephrine group had Q waves. No difference was noted between vasopressin and norepinephrine groups in the clinical diagnosis of acute myocardial infarction.
High doses of norepinephrine may cause myocardial damage, and this in turn may increase troponin levels; nonetheless, despite lower norepinephrine doses in the vasopressin group than in the norepinephrine group, no overall difference was noted in markers of myocardial ischemia such as troponin, creatine kinase levels, and ECG findings. It is relevant to note that heart rate was significantly lower in the vasopressin group than in the norepinephrine group over the first 4-day period (P = 0.033), yet again, we found no overall difference in markers of myocardial ischemia. We did not find evidence that renal dysfunction contributed to any differences between vasopressin and norepinephrine groups in markers of myocardial ischemia, in that our marker of renal function (serum creatinine over time) was not different between groups. These observations highlight the complexity and multiple factors that could contribute to myocardial ischemia in patients who have septic shock.
In critically ill patients, many mechanisms are likely responsible for the release of troponin into the systemic circulation, including impaired microvascular perfusion, reduced oxygen delivery to the heart, myocardial depression and cellular injury, and increased myocardial oxygen demand [7]. Although cardiac troponins are sensitive and relatively specific biomarkers of myocardial injury, elevations are not diagnostically specific for acute coronary syndrome, and can occur in the absence of coronary atherosclerotic disease [8]. Cardiac troponin elevation may be even less specific in critically ill patients, as many conditions are associated with increased troponin, including infection, sepsis, septic shock, hypotension, arrhythmias, pulmonary embolism, and renal insufficiency [9]. Troponin levels are frequently elevated in critically ill patients and are independently positively associated with short- and long-term mortality [10–13]. In a systematic review, 43% of 3278 critically ill patients enrolled in 20 studies had elevated troponin levels [12]. In adjusted analyses, elevated troponin was associated with an increased risk of death (OR, 2.5; 95% CI, 1.9 to 3.4; P < 0.001); in unadjusted analyses, it was associated with increased length of ICU stay of 3 days (95% CI, 1.0 to 5.1 days; P = 0.004) and hospital stay of 2.2 days (95% CI, -0.6 to 4.9 days; P = 0.12).
Although we found a similarly high prevalence of elevated troponin (approximately 30% to 35% of patients) in our study of patients who had septic shock, we did not find that increased troponin was associated with increased mortality. Published data regarding the prognostic value of troponin elevation in patients with sepsis syndrome are conflicting [14–22]. However, consistent with our results, most studies have not found that troponin elevation is an independent predictor of mortality, after adjusting for other variables [14, 16–18]. In multivariate analyses, previous trials have identified greater severity of illness and the presence of shock as independent predictors of death, as we did in our study [14, 16–18]. In contrast, whereas several small studies found increased mortality in patients with sepsis who have elevated troponin levels [19–21], only one study concluded that elevated cTnI was an independent prognosticator of mortality after adjusting for other significant variables (OR, 2.020; 95% CI, 1.153 to 3.541; P = 0.014) [22]. It is not clear whether elevated troponin is not prognostic in septic shock, or whether patient heterogeneity, or differences in timing and frequency of troponin measurement in different studies, accounts for these conflicting results.
ECGs are used in addition to serum cardiac biomarkers to diagnose cardiac ischemia in critically ill patients who are unable to communicate symptoms. However, ECG findings suggestive of ischemia, such as ST-segment deviations, are common in critically ill patients and may be nonspecific for diagnosis of acute cardiac ischemia. In our study, 48% of patients with septic shock had possible or probable ECG ischemia; however, this was not prognostic of worse clinical outcomes, even with concomitant troponin elevation. Our prevalence rate of 48% is generally consistent with that of other relevant studies. Landesberg and colleagues [23] monitored continuous 12-lead ECGs in 101 general ICU patients with known coronary artery disease, or two or more risk factors for coronary artery disease [23]. Of these patients, 21% had ischemic ST-segment changes, characterized in most by ST depression. Similarly, Kress and colleagues [24] observed ST-segment elevation or depression on continuous three-lead Holter monitoring in 24% of critically ill patients with risk factors for coronary artery disease, which was associated with a longer ICU stay. In a prospective trial evaluating myocardial ischemia during mechanical ventilation and weaning, Frazier and colleagues [25] observed ST-segment changes in 70% of 43 patients, and these patients were 60% more likely to fail an initial weaning trial.
Both vasopressin and norepinephrine are potent vasoconstrictors. In VASST, no differences were found in cardiac (clinical ischemia or acute myocardial infarction based on symptoms, ECGs, and biomarkers), mesenteric, cerebrovascular, or digital ischemic events in the vasopressin- and norepinephrine-treated groups [3]. Similarly, in this VASST substudy, the rates of ECG ischemia and troponin elevations were similar in the vasopressin and norepinephrine groups. We did find a significantly higher rate of Q waves in the norepinephrine group compared with the vasopressin group. Several small uncontrolled studies [26–29] found an occasional occurrence of cardiac ischemia during infusion of vasopressin, but the small sample size and lack of controls preclude conclusions regarding risk of cardiac ischemia due to vasopressin infusion. In contrast, vasopressin infusion is cardioprotective in models of myocardial ischemia [30, 31] and in patients with postcardiotomy shock [32]. In other studies, norepinephrine infusion was associated with cardiac ischemia and elevation of serum troponin. In the study by Landesberg and colleagues [23], norepinephrine infusion significantly predicted prolonged (>60 minutes) ischemia (OR, 3.08; CI, 0.99 to 9.60; P = 0.05) and troponin elevation in 101 general ICU patients. To the extent that vasopressin versus norepinephrine have different effects on overall cardiac function, we also found no difference between the effects of vasopressin and norepinephrine on cardiac output and cardiac function in another substudy of VASST [33].
The strengths of this substudy are the inclusion of patients meeting stringent criteria for septic shock, the multicenter representation, and prospective collection of both ECGs and troponin at four time points. Previous studies describing troponin levels in patients with sepsis did not evaluate concurrent ECGs. The ECG readers were blinded to randomization group and cardiac biomarkers. Concealed randomization of patients to blinded vasopressin or norepinephrine infusions permitted an unbiased comparison between the two groups.
This study has limitations. Although our sample size is modest, it is similar to or larger than that of many previous studies evaluating troponin levels in patients with sepsis [15–17, 19, 20]; however, we cannot exclude the possibility that our study was underpowered to detect differences in important variables. Given that patients in the vasopressin group were also receiving norepinephrine, this study is not a direct comparison of the administration of vasopressin and norepinephrine. Our study was conducted before the introduction of sensitive troponin assays, with the potential that the older-generation troponin assays were affected by renal insufficiency, resulting in false-positive troponin elevation. However, this would apply to both groups of patients, as serum creatinine was similar in the vasopressin- and norepinephrine-treated patients. The generalizability of our results is limited by our exclusion of patients with unstable coronary syndrome (acute myocardial infarction based on the combination of history, ECG, and enzyme changes),underlying chronic heart disease (NYHA III and IV), anticipated to die within 12 hours, or receiving open-label vasopressin. Given these exclusions, our study population may have been at low to moderate risk of coronary ischemia, and would thus underestimate the true prevalence of ischemia in a less restricted septic shock population. The lack of a reference standard for ECG interpretation precludes the accurate diagnosis of ischemia.
Finally, we do not have data on cardiac output, central venous saturation, or cardiac ultrasound; thus, we cannot comment on whether the observed troponin elevations indicate subclinical or more overt cardiac ischemia and dysfunction.
Troponin elevation and ECG evidence of ischemia were common, occurring in 36% and 48%, respectively, of a subgroup of patients with septic shock enrolled in VASST. No significant differences in serum troponin levels and ECG evidence of ischemia were found between the vasopressin and norepinephrine groups. In this study, neither increased troponin nor ECG evidence of ischemia predicted increased mortality risk.
Key messages
In this prospective substudy of patients with septic shock enrolled in VASST, troponin elevations were very common, occurring in up to 36% of patients.
Troponin elevation in patients with septic shock was not associated with increased mortality, compared with patients with no troponin elevation.
Cardiac ischemia on ECGs was also common, occurring in 48% of patients at one or more of the measured times; however, cardiac ischemia on ECG was not predictive of worse outcomes.
No significant differences in troponin and creatine kinase levels were found between patients treated with vasopressin and with norepinephrine, compared with those treated with norepinephrine alone. In addition, the overall incidence of ECG cardiac ischemia was similar in the two groups, and no difference was noted in the clinical diagnosis of acute myocardial infarction.
Acute Physiology and Chronic Health Evaluation II
creatine kinase
intensive care unit
interquartile range
New York Heart Association
odds ratio
standard deviation
systemic inflammatory response syndrome
Vasopressin in Severe Sepsis Trial (N Engl J Med 2008
- 358:
Anthony C Gordon is a National Institute for Health Research Clinician Scientist Fellow. Deborah J Cook holds a Research Chair of the Canadian Institutes of Health Research. Keith R Walley is a Michael Smith Foundation for Health Research Distinguished Scholar. The following persons and institutions participated in this substudy of the Vasopressin and Septic Shock Trial (VASST): Writing Committee: S Mehta (chair), JT Granton, DJ Cook, JA Russell, AC Gordon, J Singer, KR Walley, C Holmes, PC Hebert, DJ Cooper, JJ Presneill, MM Storms; Executive Committee: JA Russell (chair), KR Walley, CL Holmes, JT Granton, PC Hebert, DJ Cooper, S Mehta, J Singer, AC Gordon, MM Storms (project coordinator), S Jones (administrative assistant); Canadian Institutes of Health Research: A Gasparini; Data Management: J Singer, D Ayers, TCK Lee. Clinical centers and investigators: British Columbia: St. Paul's Hospital, JA Russell, KR Walley, DR Dorscheid, M Hameed, L Lazosky, S Helderweirt, K Foley, C Honeyman, T Terins; Vancouver General Hospital, D Chittock, J Ronco, L Smith, S Logie; Richmond General Hospital, G Martinka, S Goulding, S Silverwood, L Leung; Ontario: University Health Network-Toronto General & Toronto Western Hospitals, JT Granton, M Steinberg, A Matte; St. Joseph's Hospital, DJ Cook, E McDonald, F Clarke, A Tkaczyk, N Zytaruk; Mount Sinai Hospital, S Mehta, T Stewart, A Suri, C Martinez-Motta, R MacDonald, V Sivanantham; St. Michael's Hospital, M Ward (deceased), C Dos Santos, J Friedrich, D Scales, O Smith, I DeCampos, A Richards, H Michalopoulos, U Bakshi; Windsor-Hotel Dieu Hospital, J Muscedere, C Diemer.
Authors' Affiliations
- Lim W, Whitlock R, Khera V, Devereaux PJ, Tkaczyk A, Heels-Ansdell D, Jacka M, Cook D: Etiology of troponin elevation in critically ill patients. J Crit Care 2010, 25: 322-328. 10.1016/j.jcrc.2009.07.002View ArticlePubMedGoogle Scholar
- Hollenberg SM: Vasoactive drugs in circulatory shock. Am J Respir Crit Care Med 2011, 183: 847-855. 10.1164/rccm.201006-0972CIView ArticlePubMedGoogle Scholar
- Russell JA, Walley KR, Singer J, Gordon AC, Hébert PC, Cooper DJ, Holmes CL, Mehta S, Granton JT, Storms MM, Cook DJ, Presneill JJ, Ayers D, for the VASST Investigators: A randomised controlled trial of low dose vasopressin versus norepinephrine infusion in patients who have septic shock. N Engl J Med 2008, 358: 877-887. 10.1056/NEJMoa067373View ArticlePubMedGoogle Scholar
- Ouattara A, Landi M, Le Manach Y, Lecomte P, Leguen M, Boccara G, Coriat P, Riou B: Comparative cardiac effects of terlipressin, vasopressin, and norepinephrine on an isolated perfused rabbit heart. Anesthesiology 2005, 102: 85-92. 10.1097/00000542-200501000-00016View ArticlePubMedGoogle Scholar
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- Lim W, Holinski P, Devereaux PJ, Tkaczyk A, McDonald E, Clarke F, Qushmaq I, Terrenato I, Schunemann H, Crowther M, Cook D: Detecting myocardial infarction in critical illness using screening troponin measurements and ECG recordings. Crit Care 2008, 12: R36. Epub 2008 Mar 4 10.1186/cc6815PubMed CentralView ArticlePubMedGoogle Scholar
- Lim W, Qushmaq I, Devereaux PJ, Heels-Ansdell D, Lauzier F, Ismaila AS, Crowther MA, Cook DJ: Elevated cardiac troponin measurements in critically ill patients. Arch Intern Med 2006, 166: 2446-2454. 10.1001/archinte.166.22.2446View ArticlePubMedGoogle Scholar
- Reynolds T, Cecconi M, Collinson P, Rhodes A, Grounds RM, Hamilton MA: Raised serum cardiac troponin I concentrations predict hospital mortality in intensive care unit patients. Br J Anaesth 2012, 109: 219-24. 10.1093/bja/aes141View ArticlePubMedGoogle Scholar
- Røsjø H, Varpula M, Hagve TA, Karlsson S, Ruokonen E, Pettilä V, Omland T, FINNSEPSIS Study Group: Circulating high sensitivity troponin T in severe sepsis and septic shock: distribution, associated factors, and relation to outcome. Intensive Care Med 2011, 37: 77-85. Epub 2010 Oct 12 10.1007/s00134-010-2051-xPubMed CentralView ArticlePubMedGoogle Scholar
- Scott EC, Ho HC, Yu M, Chapital AD, Koss W, Takanish DM Jr: Pre-existing cardiac disease, troponin elevation and mortality in patients with severe sepsis and septic shock. Anaesth Intensive Care 2008, 36: 51-59.PubMedGoogle Scholar
- Brivet FG, Jacobs FM, Colin P, Prat D, Grigoriu B: Cardiac troponin level is not an independent predictor of mortality in septic patients requiring intensive care unit admission [letter]. Critical Care 2006, 10: 404. doi:10.1186/cc3990 10.1186/cc3990PubMed CentralView ArticlePubMedGoogle Scholar
- Kalla C, Raveh D, Algur N, Rudensky B, Yinnon AM, Balkin J: Incidence and significance of a positive troponin test in bacteremic patients without acute coronary syndrome. Am J Med 2008, 121: 909-915. 10.1016/j.amjmed.2008.05.037View ArticlePubMedGoogle Scholar
- Oliveira NS, Silva VR, Castelo JS, Elias-Neto J, Pereira FEL, Carvalho WB: Serum level of cardiac troponin I in pediatric patients with sepsis or septic shock. Pediatr Crit Care Med 2008, 9: 414-417. 10.1097/PCC.0b013e31817e2b33View ArticlePubMedGoogle Scholar
- Choon-ngarm T, Partpisanu P: Serum cardiac troponin-T as a prognostic marker in septic shock. J Med Assoc Thai 2008, 91: 1818-1821.PubMedGoogle Scholar
- Spies C, Haude V, Fitzner R, Schroder K, Overbeck M, Runkel N, Schaffartzik W: Serum cardiac troponin T as a prognostic marker in early sepsis. Chest 1998, 113: 1055-1063. 10.1378/chest.113.4.1055View ArticlePubMedGoogle Scholar
- Arlati S, Brenna S, Prencipe L, Marocchi A, Casella GP, Lanzani M, Gandini C: Myocardial necrosis in ICU patients with acute non-cardiac disease: a prospective study. Intensive Care Med 2000, 26: 31-37. 10.1007/s001340050008View ArticlePubMedGoogle Scholar
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- Patel BM, Chittock DR, Russell JA, Walley KR: Beneficial effects of short-term vasopressin infusion during severe septic shock. Anesthesiology 2002, 96: 576-582. 10.1097/00000542-200203000-00011View ArticlePubMedGoogle Scholar
- Okamura T, Ayajiki K, Fujioka H, Toda N: Mechanisms underlying arginine vasopressin-induced relaxation in monkey isolated coronary arteries. J Hypertens 1999, 17: 673-678. 10.1097/00004872-199917050-00011View ArticlePubMedGoogle Scholar
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This article is published under license to BioMed Central Ltd. This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


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© Copyright 2017 Topher Sparrow. All rights reserved.
Status: Finished
Genre: Romance
NOTE TO READERS: Sorry about some of the typos, I just noticed them after I published it.
That was really impressive. You have a very unique style, I like it. As for the typos you can edit them by going to Publish, then clicking on La Mariposa, then again on Mariposa, then edit away. Great job and welcome to Booksie, feel free to stop by my page and check out some of my writing. Great job!
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Spring Lounge (Boa An)
More than just a cafe-restaurant, Spring Lounge is a real family-story combining authenticity, well-being and know-how.
With a grandfather as a pastry chef at the french Embassy, and a grandmother known for her unforgettable Pho in the heart of Saigon, the Vietnamese-French cuisine quickly became an institution in the family. A generation later, my mother Kim Oanh, born in Laos opened several restaurants in this Thai influence country, then in Paris, where Vietnamese food and cakes are the delight of French people.
Born by the love of healthy and diversified cooking, by the aromas of the markets, the colors of Asia, Spring Lounge is nothing more than just a sweet and flavoured memory of our Vietnamese French family culture.
Spring Lounge – Restaurant – Bakery – Pastry – Drinks. Vietnamese – French


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Lot 14: Level Crossing Warning sign $40 penalty
Snelson Railway Collection Day 1
by Ardent Auctions
November 12, 2016
Fyshwick, AustraliaLive Auction
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Description: Level Crossing Warning sign $40 penalty
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The crew from Scoreland usually go to more exotic destinations like Florida to do their shoots, but this time they decided to head to Hungary with Christy Marks to hang out with busty sensations Jasmine Black, Karina Hart, Melissa Mandlikova and Kristy Klenot. Looks like all the girls had a good time, there just seems to be one thing missing. My penis!
Pictures from: Scoreland
1 Comment to "Hungary For Hooters"
June 12th, 2008 at 1:20 am
I give them credit for being brave enough to get naked during daylight hours.


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Chocolate-Topped Rum Pie
|Unflavored gelatin
|1 Tablespoon (1 envelope)
|Cold water
|1⁄4 Cup (4 tbs)
|4 , separated
|1 Cup (16 tbs)
|1⁄2 Teaspoon
|Hot water
|1⁄2 Cup (8 tbs)
|1⁄3 Cup (5.33 tbs)
|9 inch pastry shell
|1 Cup (16 tbs), baked and cooled
|6 Tablespoon
|Powdered sugar
|6 Tablespoon
|Unsweetened chocolate
|1 1⁄2 Ounce, melted
|Egg yolk
Soften gelatin in the cold water.
In the top of a double boiler, beat the 4 egg yolks slightly and stir in 1/2 cup of the sugar and the salt; gradually stir in the 1/2 cup hot water.
Cook over hot water, stirring constantly, until the mixture thickens.
Remove from heat and mix in softened gelatin, stirring until gelatin is dissolved.
Cool slightly, pour in rum, and beat well.
Refrigerate until the custard starts to congeal.
Beat egg whites until stiff and gradually beat in the remaining 1/2 cup sugar.
Fold into chilled rum custard.
Spoon into pastry shell; chill until firm.
Cream together the butter and powdered sugar until light and fluffy.
Stir in melted chocolate.
Add the 1 egg yolk and beat well.
Spread on pie.
Chill again.
Rate It
Nutrition Rank
Nutrition Facts
Serving size: Complete recipe
Calories 3722 Calories from Fat 1720
% Daily Value*
Total Fat 197 g302.3%
Saturated Fat 106.3 g531.7%
Trans Fat 0 g
Cholesterol 1224.5 mg408.2%
Sodium 2282.4 mg95.1%
Total Carbohydrates 402 g133.8%
Dietary Fiber 7.1 g28.2%
Sugars 298.6 g
Protein 56 g112.6%
Vitamin A 68.8% Vitamin C
Calcium 20.6% Iron 65.4%
*Based on a 2000 Calorie diet


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A fiery crash that killed three people shut down a section of the Pennsylvania Turnpike for hours yesterday in eastern Pennsylvania.
The crash involving a tandem tractor-trailer and four passenger vehicles happened around 12:30 p.m. on the westbound lanes, several miles east of the Lebanon-Lancaster exit, state police said.
Westbound lanes were closed near the scene and traffic was being detoured. Traffic was backed up for miles and turnpike officials didn't expect the highway to reopen until late last night.
Three people in one vehicle were confirmed dead, according to Carl DeFebo, a spokesman for the Pennsylvania Turnpike Commission; four others were taken to Hershey Medical Center with unspecified injuries.
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Here's another imaginative attempt to seamlessly integrate iTunes controls into OS X. Credit to @Neal Ellis for suggesting to include it into Notification Center.
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Combine the warmth, texture and practicality of our pale blond oak with the interest and stylishness of a parquet format and lay pattern. the 228mm x 76mm individual planks of the parquet ranges can be laid in a variety of different patterns to create a range of styles to suit your space.
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Choose from large wood planks or parquet or even combine the two for a more distinctive floor design.
The Art Select range has a lifetime residential guarantee. Our Guarantee has a more comprehensive description of our guarantees.
Anna Campbell
Horsham, West Sussex
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February 05, 2017
We love our new flooring
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August 10, 2015
Perfect finishing touch to our hallway
When we moved into our new home about a year ago we were in love with the small black and white tiles throughout the hallway going into the kitchen, but over time we quickly realised how impossible it is to keep white tiles looking white! The Blond Oak parquet not only looks gorgeous in our hallway, but it is also SO much easier to keep clean and look after - especially with buggies, toys, kids, cats, etc. giving it quite a battering day in and day out. Love it.
2 of 2 people found this review helpful.
Colin Mann
Penkridge ST19
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Hall parquet floor
Excellent visual effect with minimal pattern repeat. Only time will tell on durability over years. Installer, Stafford Tiling and Flooring, very thorough and professional. Highly recommend a combination of parquet with a design strip and straight plank edging. Parquet called blond oak and planks called spring oak although the same shade, which is confusing so a visit to a showroom is a must. This product confines solid wood flooring to history
5 of 5 people found this review helpful.
Brian Sansom
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December 20, 2014
Excellent flooring
Excellent product expertly fitted in our hall by Solo Carpets of Kingstanding. We are so pleased with the look and ease of cleaning.
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Peter Nellies
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Karndean Blond Oak - Looks Wonderful
Have had it laid in our large conservatory and hallway. The fitter, Michael, supplied by Essex Carpets, did an excellent job and we wish we had gone for Kardean years ago.
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Cheryl staley
Burton on Trent
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November 11, 2014
Kardean blond oak
This is amazing stuff. Well worth paying extra to get a good fitter to put it down for you. I have had it in my hallway and it looks brilliant would recommend it to anyone who needs something hard wearing.
5 of 5 people found this review helpful.
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Wide wood planks 48" x 7" (1220mm x 179mm)
The white washed oak effect of our Sorano plank is beautifully highlighted by delicate grey and blue undertones. Coupled with subtle grain details, it creates a modern and versatile backdrop to any room design.
Wide wood planks 48" x 7" (1220mm x 179mm)
To achieve a "lived in" modern traditional or modern country feel, go for our distressed White Painted Oak planks. The chalky white painted wood stripped down to reveal beige undertones looks highly realistic - without the practical limitations of real painted hardwood - and are available in a trendy wider than usual 36x6" format.
Standard wood plank 36" x 6" (915mm x 152mm)
Knight Tile's Sycamore wood effect plank has a pale buttery colour with subtle grains in a slightly grey hue. Its relatively smooth surface and subtle design make it a great plank to customise with a darker strip for a 'decking' effect or to lay on an angle with a border plank to define the space.
Slim wood planks 36" x 4" (915mm x 102mm)


text:
- 1 [uncountable, countable] confusion (about/over something) | confusion (as to something) a state of not being certain about what is happening, what you should do, what something means, etc. There is some confusion about what the correct procedure should be. a confusion as to what to do next
- 2 [uncountable, countable] confusion (between A and B) the fact of making a mistake about who somebody is or what something is To avoid confusion, please write the children's names clearly on all their school clothes. confusion between letters of the alphabet like 'o' or 'a'
- 3 [uncountable] a feeling of embarrassment when you do not understand something and are not sure what to do in a situation He looked at me in confusion and did not answer the question. Sacha felt confusion sweeping over her as she read the letter.
- 4 [uncountable] a confused situation in which people do not know what action to take Fighting had broken out and all was chaos and confusion. Her unexpected arrival threw us into total confusion. Word Origin Middle English: from Latin confusio(n-), from the verb confundere
nounjump to other results
BrE BrE//kənˈfjuːʒn//; NAmE NAmE//kənˈfjuːʒn//
Check pronunciation: confusion


text:
Provide an independent forum for those who dare to read, think, speak, and write to advance the professional, literary, and scientific understanding of sea power and other issues critical to global security.
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Submarine commander Edward L. "Ned" Beach Jr. was looking forward to a rather ordinary shakedown cruise in early February 1960. Nothing could have prepared him for what the Navy had in mind.
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Carl LaVO is the author of Slade Cutter and Back from the Deep. He has written many articles for Proceedings and Naval History, and a variety of general-interest periodicals. He has also appeared on the History Channel and lives in Bucks County, PA.
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Queen Victoria
4 out of 5 stars
Download the FREE app and meet your ship mates!
Read the best port reviews and tips for this cruise itinerary.
|Day 1
|Piraeus (Athens), Greece
|Day 2
|At Sea
|Day 3
|Istanbul, Turkey
|Day 4
|Istanbul, Turkey
|Day 5
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|Day 6
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A roll call is a space for members who are signed up for the same cruise (same ship & departure date) to connect.
Make friends BEFORE you sail, exchange tips on what to do onboard and in the ports and maybe even organize a shore excursion with your ship mates.


text:
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Lot 164: Hannah Skeele
International Fine Art Auction
by Barridoff Galleries
28 October 2016
Portland, ME, USALive Auction
Looking for the realised and estimated price?
Description: Hannah Skeele Am. 1829-1901 Sunrise Signed "H.B. Skeele" l.r. Oil on canvas 12 x 14 in. 30.5 x 35.6 cm
Condition Report: Good condition, good appearance, no apparent restoration when examined with a black light
Notes: Sunrise
Artist or Maker: Hannah Skeele
Literature: Oil on canvas
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text:
In 2012, iSuppli believes that Android will be on 75 million smartphones and Apple's iOS on 62 million devices.
Obviously Android has an advantage here, since the operating system by Google is being used on smartphones from multiple manufacturers such as Motorola, HTC and Samsung while iOS is only to be found on Apple's own phones and devices such as iPod Touch and iPad.
iSuppli also predicts that in 2014 Android's share of the global market for smartphones will be 22.8% and iPhone OS be 15.3%. The global smartphone market has grown by 50% in Q2 this year compared to Q2 last year, according to IDC.
Google CEO, Eric Schmidt, says that 200,000 Android phones are being activated each day.
Related articles you might find interesting:
- Wrap-up: Apple's Record Earnings Q3 Fiscal Results 2010
- Apple will not make a cheap iPhone
- Apple presents iPad 2 & iOS 4.3 — Yeah, I'm getting one!
- iPhone 4 (16GB) Parts Cost $187.51
- iPhone 4G: 24 Million Units To Ship In 2010


text:
Dolph is totally going to steal the hell out of the Wrestlemania pre-show.
Pre-show Notes:
– Likes, shares, tweets, comments, pins, I'll take 'em all. Speaking of which, look at this nifty sharing button! Why don't you give it a try?
– Follow WithLeather on Twitter and like it on Facebook. Follow me on Twitter too! If you like this review, I also write stuff every darn weekday for GammaSquad — we're under "Geek & Sci-fi" on the navigation bar at the top of this page!
Okay, on we go…
Best: Triple H is Happy for You
It's been said before, but Triple H really is good at being a condescending dick. Almost like he's had some practice at it. Triple H comes out and the crowd kind of mindlessly Yeses him, so he makes them feel like assholes with a deft "Hmmm, yeah, bet that feels good". He then goes on a spiel about how he's been protecting Bryan all along, which isn't true, but still, No chants aren't quite the appropriate response, so robbed of their easy chants, the audience actually starts listening to what he has to say, at which points he drops the intense, match selling stuff about crushing everybody's hopes and dreams. Why was Triple H never this good when he was doing this full time? I guess some guys just need 20 years and 13 world championships to get up to speed.
Worst: Let's Abuse Damien Sandow For No Reason!
Unfortunately Triple H couldn't make it through the opening segment without switching gears from harmless entertaining dickery to the more malignant variety by picking on Damien Sandow. Poor, sad-eyed, CM Punk physique without the tattoos Damien Sandow. This wasn't a face turn for Sandow, so why devote a segment to Triple H dumping on him? Then The Shield, who are turning face, beat up on and triple powerbomb this poor shlub. I guess The Shield had to triple powerbomb somebody to set up the end of the show, but if that's the case have Sandow come out and be a jerk rather than have the powerbomb be the final twist on a purple nurple Triple H started.
Best: Big E Wins A Match!
Dude's as surprised as anyone…
Worst: Oooooo, Somebody Fell Asleep At a Production Meeting
Hmmm, so having failed to find anything constructive and/or entertaining for Bad News Barrett to do, they've given him a new job — whining in a thinly veiled manner about petty backstage grievances!
Somehow Barrett started at "Undertaker's Wrestlemania streak" and wound around to "BAD NEWS you'll fall asleep at a meeting at work" and Michael Cole was all SNRKKSNICKER and JBL was, "What kind of a STUPID ASSHOLE gets sleepy at a meeting?!" I get sleepy watching your programming WWE — the planning process can't be much more stimulating. Cut sleepy Billy Kidman or whoever it was a break.
Best: Stealin' Tags
Is "stealing" a tag really so awful? It's WWE's one go-to for showing there's dissent within a tag team, but why is this something to get upset about? Oh, you want to come in and do all the hard work? Sure friend! A win for you is a win for me — hooray for tag team wrestling! The whole "somebody tagging themselves in is terrible because they're STEALING THE GLORY" seems to me to be the thinking of very petty, insecure minds. Interestingly the spot started to be overused around the time Triple H really got invested in the tag division, but I'm sure those two points are completely unrelated.
Anyways, I'm still giving this segment a best, because, rampant Real American tag stealing aside, this was probably the best match of the night. Cody was working overtime to make everything Cesaro did look good, including pulling this stunt…
What were you planning to do if Cesaro didn't catch you Cody? Twirl your body and bore head first into the earth like Drill Man?
Cesaro and Swagger even managed to make the rote tag stealing stuff somewhat entertaining with some good facials, and I'm glad the Usos are now important enough that they get to do crowd popping rescue spots. So yeah, a segment with nothing but good to great people in it was good, but enough tag stealing.
Best: A Competitive Bray Wyatt/Kofi Kingston Match?
A back and forth Bray Wyatt/Kofi Kingston match was low on the list of things I excepted or hoped to see on this week's Smackdown, but the match was…pretty good?
Bray is still far from a bulletproof performer, but there's a type he works well with, namely smaller guys who bump hard. Bray isn't really that big, but he works like a monster, so he needs somebody who can pinball off him, and Kofi can certainly do that. Bryan, Kofi, the smaller, wilier Shield members, Bray's worked well against all of them. Kane, Roman Reigns (and probably Cena) not so much. Bray really needs to do like Chris Jericho and have one gear for the big guys and one gear for the faster smaller guys if he wants to hang around as a top heel — he can't wrestle Bryan every night.
Worst: Oooooo, Somebody's Not Returning WWE's Calls
In a match that no doubt delighted the horny guy with a baby on his lap sitting next to me at last week's house show, Nikki Bella continued her John Cena-ing of the women's division by beating Tamina, but the real story of the segment was AJ on commentary.
See, every time Cole or JBL asked her a question AJ would ignore it, and then she got up and walked out on them. Ho ho! I see what you did there WWE! Of course Cole and JBL were so obnoxious that AJ came off as sympathetic, so joke didn't really work as a jab against Punk, but it was probably more accurate overall.
Worst: A Long-Standing Rivalry Renewed
A rivalry can't be renewed if it never ended, and I'm fairly certain Dolph Ziggler has wrestled Alberto Del Rio at least once a week for the past five years.
So yeah, the rekindling of this classic rivalry didn't do much for me. I don't know if they chopped 10-minutes out of the middle of this one, but the announcers were giving Dolph/Alberto the "What a great match!" sell even though the entire thing lasted maybe six minutes. Give them credit, they were trying hard to make this match in the second-to-last segment on Smackdown (aka the Aksana slot) seem important, but my brain wasn't having it. Honestly I'd rather have Aksana in the Aksana slot.
Then after the match Dolph fiery promo-ed his way straight to Cringetown, boasting over winning TWO STRAIGHT MATCHES, entering the battle royal we all assumed he was already in, then dramatically vowing to finally secure himself a WRESTLEMANIA MOMENT by winning a giant chocolate Andre the Giant in the opener (which he won't actually do). This promo was the equivalent of Dolph doing a 360-degree bump to the floor off a Miz clothesline — cool it dude.


text:
AOC e1659FWU 16" LED USB Powered Portable Monitor with caseLCD Monitors
Adjustable Display Angle - 1366 x 768 - 262,000 Colors - 200 Nit - 500:1 - HD - USB - 8 W - Glossy Piano Black - ENERGY STAR 6.0, RoHS, cTUVus - View Complete Details
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AOC e1659FWU 16" LED USB Powered Portable Monitor with case - 16" class USB monitor, 1366 x 768 resolution and folded stand. Landscape or portrait view mode with auto-pivot, built-in DisplayLink Technology.
e1659Fwu is the perfect USB powered portable monitor accessory for laptop and computer. The widescreen monitor receives both power and signal via a single USB cable for plug-and-play connection; it does not require a power cord or VGA cable, and comes with a removable base for maximum flexibility.
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Nice jacket IrateCustomer!
post #48391 of 78717
3/25/13 at 11:21am
Nice jacket IrateCustomer!
Nice fit, cool color scheme, VERY DAPPER! Nice work
Oh, so much better! The other way you just looked as if you were trying too hard! Now you look very nice.
CousinDonuts, I think I didn't catch this one very well, can you explain me a little bit more? The measurement of the shoulders seams across is 19.5", I need 19", I will post some pics later on the Tailor's thread.
Cravate_Noire - Wow. Awesome grays and blacks. Wouldn't have thought to wear a loose knit like that.


text: Start Managing Your Money With Just One Minute Each DayKristin Wong1/15/16 6:00amFiled to: MoneyPersonal FinanceHabits46EditPromoteShare to KinjaToggle Conversation toolsGo to permalink Money management can be intimidating, but the first step to facing your financial anxiety is coming to terms with your own financial picture. If you're not sure where to start, spend just one minute each day looking at your finances. Advertisement Money.com explains:Spend one minute each day—ideally, at the same time—to check in on your finances. The best way to do this is with an account-aggregation app, which pulls together your credit card and bank accounts and lets you scroll through all your recent transactions. (You can also use this to catch incorrect charges; I've found restaurants changing my tip or double billing me.)It's a simple enough habit, but it's one that many people overlook. It's also a simple way to ease into personal finance if you're new at it. And if you're looking for an app or tool to help you get started, we've compiled a list of favorites here. For more tips, check out the full post below. Advertisement 5 Mental Tricks That Will Save You Money | Money.comPhoto by epSos .de.Gear from Kinja DealsYour Top Five Picks For Best Water BottleBestsellers: Nest Thermostat, 2nd GenerationAutomate An Outlet For $25Reply4 repliesLeave a reply


text:
Padma Raut from village Manikwada, stands out from other rural women in more ways than one.
A gritty personality with a 'never say die' attitude;
Not a person to mull long over spilt milk, she fights back with a vengeance.
The difficulties have to bow down ultimately.
A life which has consistently thrown challenges at her from a very young age- Poverty, lack of education, lack of resources,
with mother dying of snake bite,
father being swept away and lost in flood waters.
She herself was married off as a second wife to a person who already had 2 daughters from the first marriage.
Her spirited fight back led her to try out as many things as possible. Anything which could give some money to tide things over for the next few days.
Educated only upto 1st standard in school, she worked as agricultural labourer, tried her hand in odd jobs of tailoring, working as an insurance agent, established a small shop selling stationery.
She also tried selling bangles, worked even as a barber for small children - a trade operation by a WOMAN unheard and unseen in rural India. She gets Rs.5-10 for each trimmed head, earning an average of Rs.175/- ($3) per month.
All trades with meager capital and most working only as seasonal.
Meanwhile, her husband tried to set her on fire after a drinking bout.
Life stumbled along with impending marriages of daughters, a costly affair in India, a drunkard husband, education, food …. and after some time, even her husband's death which brought fresh problems in its wake.
At such times, the question is more about survival, than rights.
After a few years her inherent spirit goaded her to tackle things squarely.
The support from GlobalGiving came along. On advice from other committee members, she sought access to a higher credit.
A loan amount of Rs.10,000 ($168) allowed her to start a small trade of spices especially red chillies, an important ingredient in Indian cooking.
She bought the chillies at wholesale prices, when the prices were low in the market.
She converted half into powder and sold this processed spices at retail prices.
Cost price = Rs.18,000 for 300 kg. of chillies.
Processing cost = Rs.1,500 for 150 kg. of chillies.
Selling price= Rs.14,000 for 140 kg of chilly-powder. (10 kg is lost in processing).
(From chillies cost of Rs.9,000 + Processing Rs.1,500 = Total cost Rs.10,500).
150 kg of whole chillies still remain in her home.
She usually keeps the selling price a few notches lower than that commanded in the market. And takes utmost care to maintain the quality of her product. Even if the profit is low, it is the business which comes to her.
She plans to expand the business further.
She has already repaid the loan amount to the federation.
This will go to help another deserted woman in need.
Her husband no more, her sole aim in life is to get a decent education for her son.
With this stability in life, her go-getter personality consistently keeps on trying to help other women with difficult lives, egging them on to step out and improve their condition. Her motto - NEVER GIVE UP !
Friends, please note that your support in terms of time or resources actually gives you and your friends a chance to help women like Padma, providing vehicles which should and will help them catch up with rest of the society.
I request you to promote this link http://www.globalgiving.org/projects/empower-deserted-women-and-widows-in-rural-india/,
Thank you !
Warm Regards from me and Padma !
Project Leader
Project Reports on GlobalGiving are posted directly to globalgiving.org by Project Leaders as they are completed, generally every 3-4 months. To protect the integrity of these documents, GlobalGiving does not alter them; therefore you may find some language or formatting issues.
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text:
Marmot Chelsea Coat
2 lb 9.1 oz / 1165.2 g
|Main Material
MemBrain® 10 2L 100% Nylon 4.0 oz / yd
|Lining Material
100% Polyester Embossed WR 1.3 oz / yd
|Insulation Material
650 Fill Goose Down
Where to Buy
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Help support this site by making your next gear purchase through one of the links above. Click a link, buy what you need, and the seller will contribute a portion of the purchase price to support Trailspace's independent gear reviews.
Manufacturer's Description
Visit Marmot's Chelsea Coat page.
Retailers' Descriptions
Here's what other sites are saying:
A down coat that's also waterproof is your ticket to comfort for outdoor winter activities.
On Sale. Free Shipping. Marmot Women's Chelsea Coat FEATURES of the Marmot Women's Chelsea Coat Marmot membrain waterproof/breathable fabric 100% seam taped 2-layer construction 700 fill power down Zip-off down filled hood with removable synthetic faux fur ruff Micro fleece lined zip handwarmer pocket Micro fleece internal cuffs Internal zippered media pocket Adjustable snap cuffs
- Moosejaw
Distinct, knee length urban-chic lines blended with serious protection from the elements, the waterproof breathable and insulated Women's Chelsea Coat from Marmot takes mountain performance to the streets. Sized specifically for women, this sleek coat is insulated with 650+ goose down wrapped in two-layer Marmot MemBrain weatherproofing that is fully seam-taped to block the worst of winter weather. A full coverage parka that is extremely warm and soft, the 650 fill power down insulated Chelsea sports a zip-off down filled hood with removable fur ruff that lets you pick the style of the day. Lightweight, packable and enduring, this down coat features a full front zip with protective storm flap, adjustable snap cuffs, and micro fleece internal cuffs to seal up the gaps against wind, snow, and the challenge of a persistent storm. With hand warmer pockets lined in toasty micro fleece and interior drop pocket, this long coat has plenty of storage for necessities and valuables. A snow parka offering exceptional warmth, head turning alpine style, and sexy city appeal, the Marmot Mountain Works Women's Chelsea Coat offers the look and feel of winter comfort.
- Altrec Outlet
Marmot Womens Chelsea Coat - Sale - Distinct, urban-chic lines and details camouflage serious protection from the elements in the waterproof, insulated Chelsea Coat. Sized specifically for women, this full-length coat starts with Marmot MemBrain, is stuffed with 650+ goose down, and features a zip-off hood with a removable fur ruff, and zip handwarmer pockets. Main Materials MemBrain 10 2L 100% Polyester Herringbone 4.6 oz/yd Lining Material 100% Polyester Embossed WR 1.3 oz/yd Insulation Material 650 Fill Goose Down Center Back Length (Base of neck to bottom of hem) 38in Fit Regular Fit Weight 2lbs 9.1oz (1165.2g)
- Massey's Outfitters
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text: 'Moonrise' movie night By Staff reports December 18, 2013 Courtesy photo Kara Hayward and Jared Gilman star in Wes Anderson's "Moonrise Kingdom, screening Friday at UUC. CHARLESTON, W.Va. -- Wes Anderson's critically-acclaimed "Moonrise Kingdom" screens for free at 7:30 p.m. Friday as part of the Third Friday Film Series at the Unitarian Universalist Congregation, 520 Kanawha Blvd. W.The quirky comedy about a pair of young lovers in 1960s New England who run away together was nominated for Best Original Screenplay at the 2013 Oscars. It also stars Bruce Willis, Edward Norton, Bill Murray, Frances McDormand, Tilda Swinton and Jason Schwartzman.The PG-13-rated film will be shown with captions for the hearing impaired. Call 304-345-5042.


text:
Try not to actually bend them! Try pulling them apart at the same time (evenly) by grabbing the headband right above the rod blocks and pulling apart a little at a time, so they form into a (U) shape.
I also mentioned in another thread, you can purchase (shaft collars) + (O-rings) to keep the height adjustment of the drivers by sliding the (O-rings) onto the tops of the rods, then sliding the (shaft collars) onto the rods and locking them with the set screw. I use the (O-ring) to protect the plastic rod blocks from the metal (shaft collars).
This works out very well.


text:
Are you looking for Vision Care in TENNESSEE? Hotfrog showcases more than 50 popular businesses related to Vision Care in TENNESSEE! Find a specific region or suburb using the left navigation.
- 09/29/2010
Chattanooga, TN
Friedrich Eye Associates, PLLC is your complete vision care practice located in Chattanooga, Tennessee offering both Ophthalmology and Optometry services
Complete Vision Careeye examOphthalmology And OptometryLenses
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We concentrate on the health of your eyes and recommend yearly eye exams Our office pursues excellence by delivering quality, affordable, and personalized vision care to all our patients Our office has bee…
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Orgain Family Vision Care, Hendersonville, TN, high quality eye care for every member of your family delivered in a warm, comfortable setting, greateyes.org, Hendersonville's trusted optometrist
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We are the only provider in the Memphis area including Collierville and Somerville that offers discount programs for vision correction procedures Our mission is to offer exceptional, personalized care and deliv…
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Crowder Eye Center is an established family optometrical practice. Taking many forms of insurance and providing the best in optometrical care and high quality, high fashion eyeware as well as offering vision therapy and …
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Cookeville, TN
Welcome to Huddleston and Shepherd Family Vision Care Located in Cookeville, TN Tennessee, our doctors are optometrists who specialize in all aspects of eye care, including glasses, contact lenses, and disease …
Family Vision Careeye examinationOptometryEyecare
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Thank you for your interest in Jessup Eye Care, providing quality eye care products and outstanding customer service to Nashville, Tennessee and its surrounding areas. Our staff is happy to guide you in every aspect of y…
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Hendersonville Eye Health & Vision, PLLC is your local optometrist in Hendersonville serving all of your vision care needs. Call us today at (615) 447-3404 for an appointment
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Bellevue Eyecare Center: Nashville, TN, (615) 662-7588 - Our eye doctor can meet all of your optical needs. We carry a variety of contact lenses and eyeglasses frames. Next to Old Harding Pediatric, our Optometrist speci…
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Old Stage Eye Care has exciting news We strive to provide the highest quality vision care and are dedicated to patient care, clinical education, and optical service
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Munford, TN
Drs. Whitley & Hughes and staff are committed to providing each patient with personal, professional vision care and exceptional patient service
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Eye healthFamily Eye CareEye Care ProceduresProgressive Lenses
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We want you to be as comfortable and secure as possible, and we know that understanding the problem better will help you feel better about the ideal vision care we provide We will also make a list of your curre…
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Jackson, TN
Discounts available for seniors, state employees, TEA members. Eye care for your entire family. Eye exams, disease treatment, optical lenses. Call 731-256-6920
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Our entire Fairview optometry staff is committed to ensuring the comfort and satisfaction of each and every patient We will do our best to accommodate your busy schedule by finding appointment times that meet y…
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Chattanooga Eyecare - Downtown Chattanooga's most convenient eyecare location features a wide range of frame designs and selections, including sunglasses. We also test for a wide range of eye health problems
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Currently, Dr. Talley serves as a Managing Partner of West Tennessee Eye, a large optometric group practice in Memphis, Tennessee
Optometric CareOptical ServicesEye healthEye Examinations
Lebanon, TN
Welcome to Famil Eye Med. Let our capable staff and doctors take care of all your vision needs! We are located in Lebanon, TN. Please call us at 615-449-0541 or visit our website for more information
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At New Vision Eyecare, our goal is to give you the best eye examination experience possible and handle all of your personal optical needs, while making you feel right at home in a warm and cozy environment
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We welcome the opportunity to earn your trust and deliver you the best eye care available in Gibson and surrounding counties Our commitment is to provide exceptional eye care and patient satisfaction to Milan a…
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Hotfrog US provides information regarding Lifetime Family Eyecare in Franklin TN. Lifetime Family Eyecare is located at 3070 Mallory Ln and provides Healthcare,Optometrist,Retail,Glasse services. Contact them on (615) 77…
eye examOptometryEyecareEye Doctors
Cordova, TN
Our entire Cordova optometry staff is committed to ensuring the comfort and satisfaction of each and every patient We will do our best to accommodate your busy schedule by finding appointment times that meet yo…
Eye healthEye ExamsOptometryGlasses
Lexington, TN
We insist on empowering education so our patients can be an active participant in their eye health care It is our mission here at Complete Family Eyecare to provide the most comprehensive and technologically ad…
Soft Contact LensesEye healthLens CareOptometry
Elizabethton, TN
Our comprehensive optometric practice proudly serves the Elizabethton community. Our eye doctors specialize in Neuro Rehab Vision Therapy and Low Vision Rehabilitation. We are able to diagnose and treat learning-related …
Eye healthOptometryeye doctoreyeglasses
Germantown, TN
Welcome to The Optical Boutique. Here you will receive the latest in eye care treatment, answers to your questions, and the latest selection of eyeglasses, contact lenses and other products at great prices
Computer Vision SyndromeEye healthEye DiseaseOrthokeratology
Surgical Eye CareContact LensesIntraocularEye Disorders
We are a group of independent optometric practices that formed an alliance to provide our patients with the absolute best eye care possible., We are a group of independent optometric practices that formed an alliance to …
Eye ExaminationsOptometryOptometric AssociationEyecare
mcminnville, tn
Locally-owned and operated eye care office in McMinnville, Tennessee founded in 1949 By W.W. Davis, O.D. and carried on by his son, Glenn Davis, M.D
Eye Care TeamEye Examseye doctorOptician
Antioch, TN
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I am an Assistant Professor of the School of Informatics and Computing at Indiana University. I also am affiliated with the NASA's Jet Propulsion Laboratory (JPL), California Institute of Technology as their Research Affiliate. Before joining IU, I was a Research Technologist within the Robotics Section of JPL from October 2011 to July 2015. Prior to that, I completed my national duty at ETRI, Korea, working as a research scientist. I received my Ph.D. from the University of Texas at Austin in 2008, and the B.S. degree from the Korea Advanced Institute of Science and Technology (KAIST) in 2004.
***JPL First-Person Interaction dataset (JPL-Interaction dataset) got updated to include our HRI 2015 videos.***
***DogCentric Activity dataset is now available! It is a new first-person video dataset taken with dogs.***
Recent News
Curriculum Vitae pdf
Publications [by topic] [by type] [by year]
List of selected recent publications
Lab membersAJ Piergiovanni (PhD student)
Alex Seewald (PhD student)
Jangwon Lee (PhD student, co-advised with Selma Sabanovic and David Crandall)
Maria Soledad Elli
TeachingI400/B457: Intro to Computer Vision (Spring 2017)
I590/B659: Vision for Intelligent Robotics (Fall 2016)
I400/B490: Intro to Computer Vision (Spring 2016)
I590/B659: Vision for Intelligent Robotics (Fall 2015)
Updated 02/04/2017


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This Gear4 mini red bird speaker is the perfect gift for an Angry Birds Space fanatic. Its a handy, palm-sized speaker that fits inside your pocket and can accompany you wherever you go. It has a 3.5mm cable, which can be connected to a smartphone, tablet or MP3 player. With multiple characters, you can daisy chain the speakers together to enjoy up to 5 songbirds chirping your favourite music.
Catalogue Number: 353-7434
- Compact size to travel with you wherever you go
- Speakers can be daisy chained
- Auxiliary input for playback of compatible devices
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Product Details
Product specifications
Power Source
Mains only
Battery Type
Number Of Batteries Required
Product Height
10.0 Centimetre
Product Width
10.0 Centimetre
Product Depth
10.0 Centimetre
Product Weight
10.0 Gram
Network & Communication


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RT @eaterla: Besha Rodell drops four glowing stars on old favorites Alimento and Sotto https://t.co/8XkxNMHyuk https://t.co/9DKcX12Wep
Located in L.A.'s historic Silver Lake neighborhood on a bustling corridor of shops and restaurants adjacent to the famous reservoir, Alimento is a creative and soulful Italian restaurant from chef and owner Zach Pollack.
Alimento draws inspiration from Italy's regional traditions while not adhering too strictly to them. Carefully sourced ingredients from local artisans and growers feature prominently among the menu's selection of small plates, pastas, and large platters designed for sharing. The food is complemented by an eclectic wine list showcasing lesser-known varietals and hard-to-find wines from small producers (many of which are organic and/or biodynamic), and by a rotating selection of microbrews from the U.S. and Italy.
Hours of Operation
Tue-Thu 5:30pm-10:00pm
Fri-Sat 5:30pm-11:00pm
Sun 5:30pm-10:00pm
Pricing: $$$
DineLA (January 13 - January 27):
Dinner: $39.00
1710 Silver Lake Blvd.
Los Angeles, CA 90026
(323) 928-2688


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Thunder Group
Straw DispensersStraw Dispensers are an essential part of any food service establishment. Straw Dispensers provide convenience and help in any scenario. Whether you are working behind a bar and use the straw dispenser to organize your condiments or you are a customer simply looking for a straw, straw dispensers are the solution for your business.
Thunder Group PLSD001 - Acrylic Straw Dispenser
List Price: $23.41
Our Price: $13.22
In Stock
Thunder Group PLSD002 - Acrylic Straw Dispenser
List Price: $51.76
Our Price: $29.24
In Stock


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The Hills Have Eyes 2 Gallery
A National Guard unit is sent to a New Mexico outpost to deliver equipment to a group of atomic scientists. When they arrive, they find the place deserted and deploy themselves into the distant mountain range to carry out a search and rescue mission; unaware that they're walking into a trap set by the family patriarch of the mutants, Papa Hades. Check out photos of what happens next in The Hills Have Eyes 2...
Roll your mouse over the left and right-hand sides of the image and then click to view more pictures.
5 of 5
Read our review of The Hills Have Eyes 2 or watch the trailer
Recent Galleries:
- John Wick: Chapter 2 Ultra Cool Illustrated Posters Gallery
- T2: Trainspotting - World Premiere Photo Gallery
- Baby Driver (Ansel Elgort/Lily James) - First-look Photo Gallery
- Alien: Covenant - First-look Photos
- Duncan Jones's Mute - First-look Photo Gallery
- T2 Trainspotting Character Posters Gallery
- Fantastic Beasts And Where To Find Them UK Premiere Photo Gallery
- John Wick: Chapter 2 First-look Photo Gallery
- Marvel's Doctor Strange Character Poster Gallery
- The Magnificent Seven: Cowboys descend on West End - Photo Gallery


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Photo: Travis Rathbone
You need only a little dressing for the slaw because the cabbage releases moisture as it sits.
Makes 2 servings (serving size: 3 1/2 cups)
Recipe Time
Prep: 10 Minutes
Nutritional Information
Calories 369
Fat 7.9 g
Satfat 0.9 g
Monofat 2.3 g
Polyfat 2.6 g
Protein 18 g
Carbohydrate 59 g
Fiber 15 g
Cholesterol 1 mg
Iron 4 mg
Sodium 430 mg
Calcium 231 mg
1/4 cup fat-free plain yogurt
1 tablespoon cider vinegar
1 tablespoon water
1/4 teaspoon kosher salt
Freshly ground black pepper
1 (15-oz) can low-sodium chickpeas, rinsed and drained
2 1/2 cups sliced packed green cabbage
2 stalks celery, thinly sliced
2 carrots, peeled with a vegetable peeler into strips or thinly sliced, or 2 cups shredded carrots
2 tablespoons sesame seeds, toasted
1. In a medium bowl, stir together the yogurt, vinegar, water, salt, and pepper to taste. Add the chickpeas, cabbage, celery, and carrots; toss to combine. Sprinkle with sesame seeds.
2. Transfer slaw to a plastic food-storage bag or 2 portable containers. Refrigerate at least 4 hours before serving; slaw keeps up to 3 days.
September 2012


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Online services progress
Over the past year we have made it easier for Queenslanders to know what services are available and how to access them.
By the end of 2015 customers will be able to:
- access more than 250 new and/or improved services online
- provide proof of identity once and log in online to apply for licences and other services
- create their own personalised online 'my account' for targeted reminders and account information
- visit the new customer centres and take part in shaping the statewide plan
- experience consistent service standards
- see that their feedback is improving services.
More information
The Queensland Government is delivering many other improvements to make services simpler, clearer and quicker for Queenslanders.
To access all Queensland Government services:
Click: www.qld.gov.au
Call: 13 QGOV (13 74 68)
Visit: local service outlet


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The Web Media fx Team of Web Professionals
Web Media fx was formed in 1998 when the internet was still just a baby.
Our passion and love of computers has evolved over the years, as has technology and knowing how to stay above the curve is how we've been able to achieve top quality hand coded projects while maintaining speed and efficiency. Our goal is 100% Client Satisfaction!
Advertisers - Marketers
Free Up Your Schedule; need interactive media - Let us do the work!
Small to Large advertising and marketing firms now have an alternative to employing massive web departments with the large salaries. Skilled develeopers need to know several languages such as php, javascript, and html/css. Now, our team can complete those projects for you at a Fraction of the cost. Call 415-601-0983 today.
Graphic and Web Designers
HASSLE FREE - Multi-Platform Tested Coding Delivered!
How many times have you created a stunning web design that you know would look great but every time you sit down to make it a website it goes horribly wrong? Stop fumbling with code you don't understand. We're here for you. Submit your design and in as little as 4 days see your vision converted to fully functional website.
Resources and Downloads
Font, Social Media Icons, Buttons, Backgrounds and so much more!
Have you ever needed a classic font that you just can't find any where else, a social media icon set, web buttons, backgrounds and so much more. Over the years we have compiled a huge library of images, buttons, etc. Follow us as we roll out our biggest collections and continue to update our library, downloads and resources.
Who We Are
The Web Media fx Team of Web Professionals