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The most recent incident, and the motivation for the protest, was a 15 year old Israeli girl being abducted and raped by 3 illegal immigrants. The girl's boyfriend was also assaulted. Recently too, there have been reprisals with Molotov attacks on the homes of two illegal African immigrants.
Rabbi Baruch Marzel Formerly Rav Kahane's (Z"L) Right Hand Man |
The problem with illegal African immigration into Israel started around 2004, when the first Sudanese refugees (and they were real refugees) were fleeing from the genocidal war of extermination against the people of S.Sudan and Darfur.
Today those real refugees total only around 500. The rest, approximately 150,000 are made up of illegal immigrants looking to work and send money back home.
Like yesteryear, the word is now out in African countries that life here is even better. Oddly enough, these only seem to be Muslim countries such as Eritrea and North Sudan, whose governments know their Islamic duty and have seized the opportunity to allow many of their citizens to head towards Israel's borders. Unlike the last few years, the Egyptian authorities now do not kill and imprison these economic migrants on their way to Israel, instead they turn a blind eye, allowing Beduin human traffickers to smuggle them here (for a fee).
These Muslims infiltrators are not traumatized by war or genocide, and do what comes naturally to Muslims, using migration as a convenient weapon to colonise a foreign land.
A few of the media come to stare in disbelief at the 'racism' of the protesters who dare oppose child rape and violence from illegal immigrants |
An Ethiopian Jew (left) accuses us of being 'racist' but doesn't seem to notice the otherJew in front of him also protesting with us |
As such, the protesters gave the leftists all the ammunition they needed, and the Alinsky-indoctrinated disciples had a field day distracting from the issues at hand, and uniting all the black people behind them, focusing instead on calling the protesters racist (what else?!).
The protesters did their best to deflect the accusations by clarifying what they meant, but better worded signs would've simply saved them the trouble, thus enabling them to go on the attack (accusing the leftists of aiding and abetting child rape etc).
But in Israel, until now, the left have not been able to utilise this tactic with the Arabs, and so the illegal African migrants have provided a golden opportunity to exploit the situation.
Some 'local' residents look on at our protest. Their eyes says it all. |
With the area de-stabilised, the leftists achieve their aim: virtual or literal civil war as we're close to seeing now. With this situation, the left have a two-pronged approach. Firstly, with the aid of the media reinforcing their message, they can turn reality on its head, pointing to the 'racist' attitude of the local Jewish Zionists as being the cause of violence, not a reaction to it. Therefore, they point to the only 'obvious' solution as being a police crackdown, not on the criminals, but on the Jewish victims.
Secondly, they can point to yet another 'failing' of the government (most likely) citing the poverty or 'social injustice' of the illegal immigrants as the reasons for the violence (or some other reason requiring a financial solution). New laws are then passed requiring more money be handed out and/or promoting these people to jobs they're completely unqualified for (multiculturalism), thus making life worse in so many ways.
The end result is that the illegal Muslim immigrants are free to continue their reign of terror, the state becomes poorer, and Israeli citizens become more angry (in the case of Israel, that anger is directed at the orthodox Jews), wondering why they served in the army and pay such high taxes. Then come summer time, they go out to protest (organised by the left) blaming the government for the situation.
Of course, the government is ultimately to blame as ultimately it has been arguing over the building of a fence along Israel's southern border for over a year now (the idea is blocked by the leftists in government, and Bibi is scared of them).
Thanks to writings of people such as Saul Alinsky, warfare has taken on a whole new meaning, with the battlefield, the weapons, the targets and the casualties, not even realising who, what, when, how or why.
Anyone who says Israel isn't a democracy because the majority (Jewish population) decides who they don't want in their country, needs to go and look up the definition of democracy. In any democracy, people have the right to decide on everything from who they let in the country, to when they go to war.
People who are a minority voice in a democracy and want to control the country or inhibit the majority's right to free speech (either at a protest or the media not airing your point of view) need to go and study the definition of fascism.
Fellow patriots wherever you are, we need to read Rules For Radicals by Saul Alinsky. Get mad, get informed, fight for freedom, and smash the left!
1. The Shadow Party By David Horowitz
Caped Crusader


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Pop Idol admits changing voting system to keep Gareth around.
Pop Idol creator and judge Nigel Lythgoe says that "a panic over the voting" led the producers to change the voting system. An e.mail campaign to vote stuttering contestant Gareth Gates out led the producers to have the public vote to keep their favorite contestants instead of having them vote out their least favorite.

subset: commoncrawl


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As a Marine, you know life's highs and lows like few others. You've trained hard, fought hard, and earned your nation's respect. But as a Marine, regardless of your rank or specialty, you are faced with challenging situations on a daily basis; combat, deployment, field duty, and frequent moves or separations from family. These situations may lead you to engage in unhealthy and risky behaviors, including turning to alcohol and prescription drugs to manage stress.
While drinking might seem to relieve some of your stress at first, it will soon begin to make the original issue worse and will likely cause additional complications. Resiliency isn't found in a bottle. The Marine Corps offers several resources for dealing with stress that don't involve turning to substances.
DSTRESS Line
The DSTRESS Line provides a 24 hour anonymous phone, chat and Skype counseling and referral service using a 'Marine-to-Marine' approach. The call center is staffed with veteran Marines, Fleet Marine Force Navy Corpsmen who were previously attached to the Marine Corps, Marine spouses and other family members, and licensed behavioral health counselors specifically trained in Marine Corps culture. DSTRESS Line's goal is to help callers develop the necessary skills required to cope with the challenges of life in the Corps. The DSTRESS Line is also available to spouses and children over 18. Children under 18 can call if a parent is present and consents to the conversation.
Community Counseling Program
The Community Counseling Program assists Marines and families in accomplishing their personal goals through short-term solution focused counseling, skill enhancement, education and referrals to other helping resources. It offers confidential care worldwide that meets individualized Marine and family needs.
Substance Abuse Program
If you think you may have an issue with drugs or alcohol the Substance Abuse Program can help. It equips Marines with education on substance misuse, relationships, stress management, emotional regulation, thinking patterns, and risk awareness, and tools to promote the safety of Marines, their families, and enhance unit performance across the Corps.
Now that you know which resources are available to you, it's time to start exhibiting low-risk behavior in your own life. Here are a few tips to get you started:
- Be aware of the risks. Drinking increases the risk of injury. Car crashes, falls, burns, drowning and suicide are all linked to alcohol and other drug misuse.
- Make no-risk to low-risk choices. High-risk drinking puts your health, career, social life and family ties at risk.
- Sweep away the myths. Having a designated driver is no excuse to drink. Drinking at home/barracks or sticking only to "beer" does not make drinking any "safer".
For more information on DSTRESS Line, Community Counseling Program, or Substance Abuse Program, visit their individual program pages.


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UberExercise — Liquify Fat AND Tear Up Your Butt, Biceps, And Quads With Lunging Biceps Curls
Posted by Bryan DiSanto on Aug 11, 2014 in Biceps, Butt, Exercises, Legs, Muscle It UP, UberExercises
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Read More


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Severn Trent Water
Flash flooding affected Suttoon Coldfield, Birmingham, in 2013 and 2014 following heavy downpours of rain.
UK Flood Barriers worked in conjunction with Severn Trent Water, surveying and installing Property Level Protection to 5 homes in Sutton Coldfield, West Midlands.
Flood mitigation products used inlcuded Flood Angel® Anti-Flood Airbricks, Flood Defender Wall Barriers and Flood Defender Doors, and waterstop.
Kitemark Certified Survey & Installation
Chas Accredited
Guarantee Protection through GGFI
UK Register of Pre-qualified construction services


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Area Sales Manager for Giant Textile Group ( 7 - 10 yrs)
RS 3,50,000 To 6,00,000 Gurgaon, Raipur - Haryana, JhariaKhas, Ranchi, Jaipur, Lucknow, Dehradun, Uttarkashi, Delhi
1.Develops Sales plans and budgets to achieve or exceed the annual sales objectives for the company. 2. Monitor and control the sales budget to ensure optimum utilization of resources in the area/ Division. 3.Generate sales of company products in t...
Key Skills : sales,marketing
Sales and Marketing ( 1 - 5 yrs)
ASB jobs now
RS 2,00,000 To 5,00,000 Hyderabad, Hyderabad Suburb, Vijayawada, Visakhapatnam, Patna, Ranchi
leading insurance company is hiring for the position of business development manager and sales manager .
Key Skills : market executive,marketing agent,sales coordinator,retail sales manager,sales,marketing,business development
Area Sales Manager ( 5 - 10 yrs)
Sunmicro Industries Ltd
RS 2,25,000 To 3,50,000 Patna, Ranchi, Asansol, Durgapur-Barddhaman, Jalpaiguri, Kolkata, Siliguri-Darjeeling
Experience : Must have Minimum 6 Years Experience in Hard Core Sales in Fmcg or Fmcd Sectors. age :not More Than 36 Years qualification : Graduate But Mba Preferred. package :2.4 Lacs per Annuam positions :west Bengal, Bihar...
Key Skills : sales,area sales manager,marketing manager,business development
Kou-chan Knowledge Convergence Pvt. Ltd.
RS 1,25,000 To 1,75,000 Patna, Ranchi, Bhubaneswar, Kolkata
• Must have sales experience in hard core sales industry (Banking & Car Deal Retail) is preferred. • Manages personnel and develops sales and sales support staff. • Reviews progress of sales roles throughout the company. • Accurately for...
Key Skills : sales manager,marketing manager,business development manager,customer sales manager
Seeking for Event Manager ( 1 yrs)
Navkirti Web Media & Technologies Pvt. Ltd.
Hyderabad, Guwahati, Silchar, Patna, Chandigarh, Raipur, South Delhi, Ahmedabad, Dhanbad, Ranchi, Mumbai, Pune, Bhubaneswar, Jaipur
We are looking for people who are planning to start a new event management and/or Outdoor advertising company. Navkirti is a decade old event management company based in Kolkata, W.B, India. and we are excelled in providing services to corporate h...
Key Skills : event manager,event management,corporate events,marketing,sales,business development,event planner,party planner,event organizer
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Sr. Engineer/ Asst Manager (Tech Sales) – Sales & Marketing ( 3 - 7 yrs)
Network 369
RS 3,00,000 To 9,00,000 Guwahati, Chandigarh, Ranchi, Bangalore, Chennai
1. Selling Building materials of Technical nature 2. Experience of dealing with Architects / Structural Consultants. 3. Product presentation, routine follow up with projects and institutions 4. Detailed technical presentations & discussions with ...
Key Skills : sales,architects,civil engineer
Sales Manager -patna ( 2 - 9 yrs)
Somya info edge services Pvt Ltd
RS 1,00,000 To 3,50,000 Patna, Ranchi, Kolkata
Role Category:Retail Sales Role:Sales/Business Development Manager Keyskills Sales Business Development Residential Sales Channel Sales Broker Desired Candidate Profile Education- Ug: Any Graduate - Any Specialization, Graduation No...
Key Skills : sales executive,marketing,distribution,business development executive,business developer,regional manager,head sales,channel sales,sales...
Area Sales Manager ( 1 - 10 yrs)
Words Worth
RS 50,000 To 5,00,000 Hyderabad, Chandigarh, Gurgaon, Raipur - Haryana, Ranchi, Bangalore, Kolkata, Delhi
Required experience: Minimum 1 year experience ; Fresher's may also apply Proven track record of working with administration at educational institutions and school districts, effective territory management and exceptional relationship-building c...
Key Skills : sales,area sales manager,regional sales manager,educational sales manager,business development
Business Development Officer ( 0 - 2 yrs)
Kredit Foundation
RS 1,00,000 To 1,25,000 Bhagalpur, Purnia, Jamshedpur, Ranchi, Mumbai, Mumbai Suburb, Nagapur, Pune Suburb, Thane
Qualification Requirements: To Perform This Job Successfully, An Individual Must Be Able To Perform Each Essential Duty Satisfactorily. The Requirements Listed Below Are Representative Of The Knowledge, Skill, And/Or Ability Required. Reasonable A...
Key Skills : business developer,sales executive,marketing,distribution,business development executive,regional manager,head sales,channel sales
District Sales & Services Coordinator ( 1 - 4 yrs)
Kredit Foundation
RS 1,00,000 To 1,25,000 Aurangabad - Bihar, Bhagalpur, Gaya, Patna, Bilaspur, Korba, Raipur, Ranchi, Cuttack, Rourkela, Sambalpur, Asansol, Kolkata, Kolkata Suburb, Malda
Analyzes, recruit Customer Service Point/ Retailers (Banking/ Web Based) customer need and defines potential market segments, potential customers, and the competitive environment to develop a plan for new product introduction. Estimates market value ...
Key Skills : customer service executive,district sales,services coordinator
Sr Business Development Manager ( 1 yrs)
RS 2,00,000 To 2,50,000 Ranchi
We are Looking for Sr Business Development Manager Candidate Should have Well Communication and Well Marketing Skill.
Key Skills : business development manager,business development,marketing
Real Business
RS 3,00,000 To 4,00,000 Durg, Raipur, Ranchi, Bangalore, Mumbai, Nagpur, Bhubaneswar, Chennai, Lucknow, Varanasi, Bihar
We are Urgent required 100 sales executive for collection Advertisement as per our tariff . Contact us for direct joining. Tarms of Joining as mentioned below :- 1. Sales Executive :- We have not required your any interview you can direc...
Key Skills : sales executive,area sales manager,marketing executive,business development executive,customer sales executive
Branch Manager (sales & Marketing) ( 6 yrs)
RS 2,25,000 To 3,75,000 Ranchi
We are Looking for Branch Manager in Pharma Division Bihar, Jharkhand, Chattisgard, Rajasthan, Maharashtra. we Will Offer Salary to Him 20k to 30k+ta+da and Want Experience 7 to 8 Year as a Mr + Team Manager Pharma Sales. we Will Offer Salary to Hi...
Key Skills : branch manager,sales,marketing,business development
Business Development Officer ( 0 - 3 yrs)
Glorious Group
RS 1,25,000 To 1,50,000 Patna, Jamshedpur, Ranchi
Essentially, Business Development, as the Title Implies, is a Results Driven Role. a Business Development Manager is Responsible for Understanding What is Going On in Their Field of Specialty, Knowing the People that Matter and are Usually Given Task...
Key Skills : sales and marketing experience in recruitment,hr services,marketing,distribution,management consulting,strategic planning,training industry,...
Requirement for Financial Services ( 0 - 1 yrs)
R.s. Consultancy Services
RS 1,25,000 To 1,50,000 Bhagalpur, Hajipur-Vaishali, Muzaffarpur, Patna, Samastipur, Bokaro, Hazaribag, Jamshedpur, Ranchi
Business Development Manager Qual.-Bachelor's Degree Age-25 to 40 Years Experience : Insurance Sales will be Preferred No. Post-12
Key Skills : sales,insurance executive,sales manager,financial service manager,marketing manager,customer sales manager,business development manager
Omniresource Business Solution
RS 1,00,000 To 1,50,000 Begusarai, Bhagalpur, Gaya, Muzaffarpur, Bokaro, Dhanbad, Ranchi
Urgent Hiring For Mis Executive – Male Candidate Candidate Should Have Experience In Mis Work. And Good Knowledge In V Lookup / Pivot Table In Excel. And Ms - Access. Qualification: Graduate With Good Communication Skill In English No Of...
Key Skills : sales executive,marketing,distribution,business development executive,business developer,regional manager,head sales,channel sales,sales...
Trainee Assistant Branch Manager /Branch Manager ( 0 - 1 yrs)
Cosmos Jobs Consultancy
RS 70,000 To 3,00,000 Hyderabad, Vijayawada, Raipur, Dhanbad, Ranchi, Bangalore, Bhubaneswar, Cuttack, Chennai, Asansol, Durgapur-Barddhaman
An opportunity to upgrade yourself and improve your professional skills with us. we offer numerous opportunities for motivated and interested individuals. One of the 4 star and is a well established and rapidly growing FMCG Company with wide network...
Key Skills : sales manager,sales,marketing,business development
Sales Tech , Manager, Sr. Executives Etc. ( 2 - 10 yrs)
RS 1,00,000 To 6,00,000 Hyderabad, Anand Nagar, Guwahati, Bhagalpur, Muzaffarpur, Patna, North Delhi, Ranchi, Bikaner, Jodhpur, Varanasi, Delhi
markt , team handeling, co-ordinating managing.....etc
Key Skills : b.tech,electronics & communication engineer,graduate,m.a,etc...english communication,sales executive,marketing,business development executive
Business Development Manager ( 0 - 3 yrs)
Glorious Group
RS 1,75,000 To 2,25,000 Patna, Jamshedpur, Ranchi
Responsible for the Administration and Efficient Daily Operation of a Full Service Branch Office, Including Operations, Lending, Product Sales, Customer Service, and Security and Safety in Accordance with the Branch Objectives.etc.
Key Skills : sales and marketing experience in recruitment,hr services,marketing,distribution,management consulting,strategic planning,training industry,...
Sales Officer- Icici Bank ( 0 - 2 yrs)
Yuva Skill Academy
RS 1,25,000 To 1,50,000 Guntur, Omerkhandaira, Patna, Bhilai Charoda, Bilaspur, Chharchha, Chhuikhadan, Raigarh, Raipur, Ranchi, Bhubaneswar, Cuttack, Rourkela
Job Profile: 1. This Is A Permanent Job & On Rolls Of Icici Bank 2. This Is A Sales Job And Not Branch Operations Job. Requires Field Work. 3. Will Be Required To Generate Business For Designated Branch In The Assigned Geography. 4. Sales...
Key Skills : good communication skills,sales / marketing,sales executive,marketing,distribution,business development executive,business developer,regional...
Business Development Manager ( 2 yrs)
Mind Multiplier
RS 80,000 To 1,50,000 Dhanbad, Ranchi, Bhopal, Indore
Business Development, Franchise Development, School Tie-ups for the Existing Product, Workshop or Presentation of the Existing Educational Product.
Key Skills : Business Development Manager,Marketing Manager,Merchandiser
Associate Sales Manager/Sales Trainee(Fresher) in West Bengal & New Delhi ( 1 - 5 yrs)
RS 2,00,000 To 3,50,000 Patna, North Delhi, South Delhi, East Delhi, West Delhi, Central Delhi, Jamshedpur, Ranchi, Delhi, Howrah
Client Name: IndusInd Bank Ltd Position: Associate Sales Manager/Associate Sales Trainee(Fresher) Salary Offered: 10k for fresher and for experienced 2.25 L p.a Location: Guwahati/Kolkata/Raipur/Indore Qualifications: Any Graduate / PG/ MBA Ex...
Key Skills : executive marketing,back office executive,business development
Idream Consulting
RS 4,00,000 To 5,50,000 Patna, Raipur, Ranchi, Bhubaneswar, Kolkata, Siliguri-Jalpaiguri
We are Looking for Smart Dynamic Individuals At Different Levels of Broking Business. Being a Growing Organization, It is An Ideal Place for Individuals with High Ambitions. the Working Atmosphere is Highly Charged with a Young and Energetic Team of ...
Key Skills : client relationship manager,wealth manager,financial advisory,relationship manager,financial...
Sunmicro Industries Ltd
RS 1,00,000 To 2,25,000 Patna, Ranchi, Asansol, Durgapur-Barddhaman, Kolkata, Siliguri-Darjeeling
Experience : Must have Minimum 3 Years Experience in Hard Core Sales in Fmcg or Fmcd Sectors. age : Not More Than 30 Years qualification : Graduate But Mba Preferred. package : 1.2 Lacs per Annuam positions...
Key Skills : sales,area sales manager,marketing manager,business development
Marketing Manager ( 1 - 5 yrs)
Tennis cricket club of india
RS 2,50,000 To 6,00,000 Hyderabad, Vijayawada, Raipur, Ranchi, Bangalore, Thiruvananthapuram, Mumbai, Bhubaneswar, Chennai, Panjim
We are Tennis Cricket CLUB of India.We are going to do event of ITCL Indian Tennis Cricket league We are looking for the Marketing for this event. and We are going to Auction of State team & District team . So We are looking for marketing people w...
Key Skills : marketing manager,online marketing executive,business development,sales
Avkul Marketing Pvt. Ltd.
RS 1,00,000 To 2,50,000 Bokaro, Dhanbad, Giridih, Gumla, Hazaribag, Ranchi
Job Title: Business Manager department: Sales & Marketing Deptt. working Area: as per Preference job Objective: responsible for the Development and Performance of all Sales Activities in Assigned Area & Market. Staffs And directs a Sales...
Key Skills : marketing,b2b sales,sales,business development
Account Manager - Sales ( 3 - 8 yrs)
Elance Group
RS 4,00,000 To 8,00,000 Hyderabad, Ranchi, Bangalore, Calicut, Mumbai, Chennai, Coimbatore, Delhi
Handling Direct sales of Data/ Voice/ Video Business, in Market · Key Account Management · Responsible for Debtor Control for the Sales orders taken · Responsible for direct business. · Is responsible for the m...
Key Skills : sales manager,business development head
Assistant Sales Manager ( 1 yrs)
Crest Manpower Sevices
RS 3,50,000 To 4,25,000 Ranchi
Dear Candidate, We are currently hiring for Relationship Manager in MNC on urgent basis. The company & job profile are enlisted below: Company Profile:- Its is an international provider (MNC) of Banking, insurance, pension, and asset man...
Key Skills : sales,marketing,business development,insurance,assistant sales manager,sales manager
Area Sales Manager ( 0 - 2 yrs)
Avkul Marketing Pvt. Ltd.
RS 50,000 To 2,50,000 Hyderabad, Jagtial, Bhagalpur, Gaya, Jagdishpur, Jamalpur, Jamhaur, Patna, Dhanbad, Jharia, JhariaKhas, Ranchi
JOB RESPONSIBILITIES: -Prepare the sales team. -Controls expenses to meet budget guidelines. -Develops a business plan and sales strategy for the market. -Responsible to generate and develop the channel and channel sales. -Provides timely feedba...
Key Skills : marketing,sales,product presentation,business development,marketing executive,sales executive,business...
Kou-chan Knowledge Convergence Pvt. Ltd.
RS 1,25,000 To 1,75,000 Aurangabad - Bihar, Gaya, Ranchi
- Must have sales experience in hard core sales industry (Banking & Car Deal Retail) is preferred. - Manages personnel and develops sales and sales support staff. - Reviews progress of sales roles throughout the company. - Accurately forecasts a...
Key Skills : sales manager,marketing manager,business development manager
Kou-chan Knowledge Convergence Pvt. Ltd.
RS 1,25,000 To 1,50,000 Patna, Ranchi, Bhubaneswar, Asansol, Durgapur-Barddhaman
- Identifying Training and Development Needs Within An Organization Through Job Analysis, Appraisal Schemes and Regular Consultation with Business Managers and Human Resources Departments; - Designing and Expanding Training and Development Programme...
Key Skills : hr trainer,hr,hr recruiter,human resource development executive,human resource management executive
opening for sales manager ( 0 - 1 yrs)
Avkul Marketing Pvt. Ltd.
RS 1,00,000 To 2,50,000 Guwahati, Rangapara, Dhanbad, Giridih, Jharia, Ranchi
Job Description job Title: Business Manager department: Sales & Marketing Deptt. working Area: as per Preference job Objective: responsible for the Development and Performance of all Sales Activities in Assigned Area & Market. Staffs And...
Key Skills : marketing,b2b sales,sales,business development,sales manager
Required Area Sales Manager ( 3 yrs)
Vardhman Consultancy Services
RS 2,25,000 To 2,75,000 Muzaffarpur, Ahmedabad, Rajkot, Surat, Vadodara, Ranchi, Mumbai
1. Leading Business Development Vertical By Proposing Strategy, Execution and Impact Analysis and Focusing On Results. 2. Identifying Marketing and Business Development By New Clients and Forecasting Projected Business. 3. Responsible for Sales Tar...
Key Skills : area sales manager,area sales officer,medical executive
Area Sales Officer ( 0 - 2 yrs)
Hamilton Paints Pvt Ltd
RS 1,00,000 To 2,00,000 Patna, Ranchi, Bhopal, Jaipur, Lucknow
1. Responsible for developing Dealer & Distribution Network.. 2. Competitor analysis & Recommendations. 3. Leading and managing a team and maintaining regular interaction with dealers and channel partners. 4. Enhancing the brand and product image ...
Key Skills : sales,area sales officer,marketing manager,customer sales manager,business development manager
Area Sales Manager ( 0 - 1 yrs)
Avkul Marketing Pvt. Ltd.
RS 1,00,000 To 2,50,000 Bokaro, Chatra, Dhanbad, Dumka, Garhwa, Giridih, Gumla, Jamtara, Lohardaga, Ramgarh Cantonment, Ranchi
JOB RESPONSIBILITIES: -Prepare the sales team. -Controls expenses to meet budget guidelines. -Develops a business plan and sales strategy for the market. -Responsible to generate and develop the channel and channel sales. -Provides timely feedba...
Key Skills : marketing,sales,business development,area sales manager,marketing manager,marketing...
Associate Business Development Manager ( Fresher)
Lue Infoservices Pvt Ltd
RS 1,00,000 To 2,00,000 Patna, Ranchi
1.Responsible for Marketing & Sales of various products. 2.Researching and analyzing the market trends. 3.Identifying/Analyzing target markets and how best to reach them. 4.Coming up with marketing strategies and to monitor, review and repo...
Key Skills : business development manager,business development,business development head,business development officer,business...
Maitre Placement Services
RS 1,25,000 To 2,25,000 Ranchi
Maintains sales volume, product mix, and selling price by keeping current with supply and demand, changing trends, economic indicators, and competitors. Establishes and adjusts selling prices by monitoring costs, competition, and supply and demand. ...
Key Skills : sales,marketing,business development,sales manager
Area Operation Manager ( 3 - 7 yrs)
Kredit Foundation
RS 1,75,000 To 2,25,000 India
Analyzes, recruit Customer Service Point/ Retailers (Banking/ Web Based) customer need and defines potential market segments, potential customers, and the competitive environment to develop a plan for new product introduction. Estimates market value ...
Key Skills : sales,operation manager,marketing,business development,area operation manager
Business Development Executive (ranchi) ( 0 - 3 yrs)
RS 2,75,000 To 3,75,000 Ranchi
Eligibility: Mba/ Mbm/bba/bbm/any Graduate with Experience in Sales & Marketing. skills: Venue Sales, Strong Communication Skills, Multitasking, Team Leading and Motivational Ability.. experience: 1-2 Years. remuneration: 17,000/- + Incentives ...
Key Skills : marketing,sales,communication,business development
Godrej Appliances : Channel Sales Trainee ( Fresher)
Godrej & Boyce Mfg. Co. Ltd
Hyderabad, Guwahati, Patna, Raipur, Ranchi, Bangalore, Mumbai, Nagpur, Lucknow, Asansol, Durgapur-Barddhaman
KRA: - Market share, Reach, Addressability, Volume & Product Mix related Objectives - Channel Strategy Development - Quality of sales - Hygiene (monitoring of outstandings etc.) - Dealer Management - Canvasser Management. JD: - Achievi...
Key Skills : channel sales management,mba,channel sales trainee,channel sales,trade sales manager,channel sales executive
Part Time Job / Full Time Job / Work At Home Job ( 1 - 31 yrs)
Forever Living Products
RS 50,000 To 1,00,000 Guwahati, Uttar Krishnapur, Aurangabad - Bihar, Gaya, North Delhi, Gurgaon, Raipur - Haryana, Dhanbad, Jharia, JhariaKhas, Ranchi, Kolkata, Uttar Durgapur, Delhi
Hi All, Anyone who is interested to do Part Time / Full Time / Work at Home in the field of Marketing / Sales call We are looking good sales boys / sales girls / house wife , who have good communication skills & pleasing personality. Experie...
Key Skills : marketing,sales,sales representative,sales officer,sales manager,sales head,business development executive
Need for Sales Manager ( 1 yrs)
RS 1,00,000 To 2,00,000 Ranchi
Sales Manager (commercial Vehicles) In- in - Jharakhand, Bokaro, Dhanbad, Ranchi, Hazaribagh, Jamshedpur
Key Skills : direct marketing,direct sales executive,sales,business development,telemarketing,telesales,direct sales
Teritory Sales Manager ( 2 - 5 yrs)
G Lite Energy Pvt. Ltd.
RS 2,50,000 To 3,00,000 Goalpara, Guwahati, Patna, Raipur, Ranchi, Shillong, Cuttack, Agartala, Lucknow, Kolkata, Delhi
Candidate Must Be Graduate, if M.b.a. Then It's Extra, Minimum 5 Years of Experience On Same Position is Must. Must Aware with Computer Knowledge and Team Handling.
Key Skills : teritory sales manager,marketing,business development
Senior Reltionship Manager ( 4 - 5 yrs)
Corporate Resources
RS 3,25,000 To 3,75,000 Guwahati, Patna, Chandigarh, Raipur, Ranchi, Bhubaneswar, Cuttack
Acquire & manage portfolio of Mid Market clients. Manage end to end clients engagements. Manage credit memo preparation& presentation.
Key Skills : marketing consultant,sales representative,sales officer,sales manager,sales head,business development executive
Relationship Manager Hiring in Jharkhand ( 1 yrs)
RS 1,25,000 To 2,25,000 Bokaro, BokaroSteelCity, Dhanbad, Dumka, Hazaribag, Jamshedpur, Ranchi
Working Closely With Clients, An RM will execute Trade On Behalf Of the Client, Continuously provide Them Investment Advice and attempt to meet their clients Financial and investment goals- Key Responsibilities include: - Know market Sentiment via...
Key Skills : customer relationship manager,client relationship manager,relationship management,business development,client...
P S Global
RS 1,50,000 To 2,00,000 Bokaro, Dhanbad, Dumka, Gumla, Hazaribag, Jamshedpur, Ranchi
Make Csp(customer Service Point) of Bank of Baroda and State Bank of India in all District of Jharkhand and Maharashtra. should Be Motercycle with Driving Licence Must. local Candidate Will Be Prefer.
Key Skills : sales executive,marketing,distribution,business development executive,business developer,regional manager,head sales,channel sales,...
Required Branch Sales Officer in MNC Bank Hirring in - Jharkhand ( 1 yrs)
RS 1,50,000 To 2,50,000 Bokaro, Chatra, Dhanbad, Garhwa, Gumia, Jamshedpur, Jugsalai, Ranchi, Saraidhela, Khunti,Sahibganj
VACANCY DETAILS Job Title : Branch Sales Officer in MNC Bank Hirring in - Jharkhand , Bihar & West Bangal Gender Preference : Male Number Of Vacancy : 65 Industry Area : Sales/Marketing Key Skills : Marketing Qualification : Bachelor Degr...
Key Skills : branch sales officer,sales officer,sales,business development,direct marketing,marketing,business...
area sales manager ( 0 - 5 yrs)
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JOB RESPONSIBILITIES: -Prepare the sales team. -Controls expenses to meet budget guidelines. -Develops a business plan and sales strategy for the market. -Responsible to generate and develop the channel and channel sales. -Provides timely fee...
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Sr. Business Development Manager(bihar) ( 2 yrs)
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We are Looking for Sr. Business Development Manager for Bihar & Jharkhand Location.
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Business Development Manager ( 0 - 5 yrs)
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Key Skills : business development manager,sales,marketing,sales executive,marketing executive,sales...


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You must register to post or download hacks.
If you are having any issues, shoot us an email, Contact MPGH Support. As always, have fun and enjoy your stay! - MPGH Staff
Its really annoying when those legit noobs always kick me.
How do you get kicked? :S
tum0r (01-30-2010)
you cant get kicked in mw2


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Project Description
This is a custom Charlotte North Carolina Real Estate Website Design that generates several leads a day. This client had IMCD integrate a custom map on the home page so visitors could click on any city they wanted to know more about and also view available properties for sale. This custom website was built to include a SEO Friendly IDX Broker integration, custom Home Page, IMCD's Featured Listing tool, a WordPress Real Estate Blog, and a custom CMS for the Community pages. This real estate website was custom built from the ground up with custom graphics, hand coded custom css, hand coded custom HTML and custom coding for the Featured Listing tool, Contact Page and the Community CMS.
Project Details
Client Keller Williams Realty
Date Launched in 2009
Skills Graphics, IDX, SEO, WordPress, Custom Web Design
View NCCharlotteHomes.com
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About this recipe: These muffins are delicious when eaten still warm, just baked out of the oven!!! They have a slightly bread-like texture and are really cheesy.
I love these muffins. I made up a batch and added 1 tomato, chopped and 6 spring onions, chopped. They were delicious for a light tea. - 17 Oct 2011 (Review from Allrecipes UK | Ireland)
Altered ingredient amounts. added bacon and diced onion. Yum - 12 Sep 2010 (Review from Allrecipes AU | NZ)


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The BEST part of My Dog is as Smelly as Dirty Socks is the illustrations. In the story, a young girl improves her family portraits by chosing objects to represent characteristics of her family. For instance, the father is playful (so his nose is a top), the mother is sweet (her eyes are cookies), the brother is sneaky (his mouth is a snake), and of course the dog is made from an old stinky sock.
I had been wanting to create family portraits with Logan but he is not actually drawing people yet. I wasn't sure if drawing faces would even work. SO... I came up with this idea.
I cut out ovals for the faces. Then I gave Logan contact paper to build a face on (we put the colored oval under the contact paper so that he could see the face area). Then we used a variety of materials for eyes, nose, mouth, and hair.
Because I am a control freak, I divided the objects up into 4 paper plates. I would give him a plate to choose from for the eyes. (He always knew where to put the eyes). Then I would give him a plate to choose from for the nose, etc. (The other face parts were hard for him. He would hold the object up to his own face first to figure out where it went. lol)
Some of objects we used were:
buttons, beads, scrapbooking embellishments, feathers, pipecleaners, yarn, cotton balls,.
Here is our family:
(I let Logan do most of the art, but I did help him put Daddy's hair on. I also convinced him to use the heart die cut that said, "Hot stuff"... moms gotta have fun too!) I wish my pictures were better- photography is not my "thing" and the contact paper is glaring!- Also we used peach paper... it looks orange, we're not pumpkins, promise!)
This is not only an awesome opportunity for preschoolers, but older students could do a lot of great writing with these portraits. This book is a must-have. Run, don't walk, to your library to check it out... umm, on second thought, don't run in the library. Librarians frown on such things!


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#WhiteWashedOUT Tweets That Accurately Portray The Frustrations All Asian-Americans Feel
There's a storm brewing on Twitter at the moment, and frankly, it's been a long time coming. Under the viral hashtag #WhiteWashedOUT this week, thousands of tweets conveyed the accumulated frustrations of the Asian-American community, specifically those in the media who so often fall victim to the trend known as "white-washing." In a scathing post on Facebook this week, actor George Takei took Hollywood to task for refusing to cast more Asian-Americans in roles that had originally been written for them.
"So let me get this straight. You cast a white actress so you wouldn't hurt sales…in Asia?" Takei wrote, referencing Marvel's recent run-in with fans angry that the company had cast white actress Tilda Swinton as The Ancient One, a role many believed had originally been written for an Asian actor. "This backpedaling is nearly as cringeworthy as the casting. Marvel must think we're all idiots."
Just last week, Marvel issued a statement to Mashable in which the company defended its casting decision, noting,
.@GeorgeTakei speaking on the @Marvel #DoctorStrange casting of Tilda Swinton as the Ancient One #whitewashedOUT pic.twitter.com/KJPzHn88wY
— Matthew A. Cherry (@MatthewACherry) May 3, 2016
Takei quickly fired back in the comments section of his original post. "Marvel already addressed the Tibetan question by setting the action and The Ancient One in Kathmandu, Nepal in the film," he wrote. "[...] So this is a red herring, and it's insulting that they expect us to buy their explanation. They cast Tilda because they believe white audiences want to see white faces. Audiences, too, should be aware of how dumb and out of touch the studios think we are."
On Tuesday, Takei's Asian-American supporters (and supporters of diversity everywhere) took to Twitter to vent their collective experiences as a community, employing the hashtag #WhiteWashedOUT, which was jumpstarted by the group Nerds of Color:
You guys. #whitewashedOUT is some piping hot truth. Just sit back and read and let these things sink in. Don't argue. Don't be petty. Read.
— Patty Miranda (@thepattymiranda) May 3, 2016
Growing up wishing you were white so you could be characters in stories #whitewashedOUT
— Anna Akana (@AnnaAkana) May 3, 2016
Once more for the people in the back #WhiteWashedOUT pic.twitter.com/Em5HApU0s6
— Matthew A. Cherry (@MatthewACherry) May 3, 2016
My biracial Asian American kids have never seen a single kids' movie or show starring girls who look like them. #whitewashedOUT
— Nicole Chung (@nicole_soojung) May 3, 2016
Growing up #whitewashedOUT means all my childhood heroes never looked like me.
— Jon Tsuei (@jontsuei) May 3, 2016
Being #whitewashedOUT means I was called a "chink" and "chinaman" by age 6. I felt only other API would accept me.
— Jon Tsuei (@jontsuei) May 3, 2016
#whitewashedOUT means the continued stereotype of the unattractive Asian male, the submissive Asian woman, the tiger mom, etc.
— Ellen Oh (@ElloEllenOh) May 3, 2016
It took me a long time to be proud to be Asian. I make sure that my kids never feel that way. #whitewashedOUT powerful stories. Read it.
— Kristy Mauna (@krissssm) May 3, 2016
#whitewashedOUT means that there are white ppl who think our hashtag, our need to tell our stories, is aimed at keeping them silent.
— Preeti Chhibber (@runwithskizzers) May 3, 2016
POC identify w white protagonists all the time R white people so devoid of humanity they can't identify with POC heroes? #whitewashedOUT
— David Mura (@MuraDavid) May 3, 2016
#whitewashedOUT meant it took years for me to realize writing Asian protags was possible. I cast myself as the sidekick in my own stories.
— Sarah Kuhn (@sarahkuhn) May 3, 2016
#whitewashedOUT means white ppl can find themselves in India and have movies made, but I can't find myself in the US at all.
— Preeti Chhibber (@runwithskizzers) May 3, 2016
#whitewashedOUT when you cling desperately to a chara bc they're literally the only 1 who looks like you on the show pic.twitter.com/lf4Cqh3Zdw
— clara mae (@ubeempress) May 3, 2016
#whitewashedOUT means that we get the message time and time again that white people are better at being Asian than we are.
— Swapna Skywalker (@skrishna) May 3, 2016
Was asked to teach white actors how to do "Asian" make-up for a show bc they didn't cast AAPI. I refused #whitewashedOUT
— Thien-Kim Lam (@thienkim) May 3, 2016
If you accept a role that was meant to played by an Asian actor, then I consider you a part of the problem. #whitewashedOUT #workisnotwork
— Richard Chan (@richardzwchan) May 3, 2016
A few celebrities chimed in as well, including comedian Margaret Cho, who had stern words for Hollywood casting agents:
Not a sidekick. Not a sidechick. #whitewashedOUT
— Margaret Cho (@margaretcho) May 3, 2016
Those who say racism doesn't exist anymore are the biggest perpetuators of it #whitewashedOUT
— Margaret Cho (@margaretcho) May 3, 2016
According to The New York Times and a recent study by the Ralph J. Bunche Center for African American Studies at the University of California, Los Angeles, films with diverse leads actually tend to garner higher box-office totals and an overall better return on investment — facts that fly directly in the face of the popular "diversity doesn't make money" argument that plagued the hashtag on Tuesday as well.
"When your response is 'let me tell you how it works,' it sounds like you're saying we need you to educate us," comic book author Jon Tsuei wrote in a tweet last week, pointing out the ridiculousness in that same sort of argument.
The #WhiteWashedOUT hashtag this week didn't just serve as a vent-session for Asian-Americans to call out Hollywood's obvious whitewashing problem, it also allowed for real dialogue to take place and gave voice to a group that is often overlooked or ignored. Now it's up to Hollywood to actually listen.


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Livni's Guidance on Arab Democracy
PALESTINE / ISRAEL, 14 March 2011
Robert Grenier – Al Jazeera
Tzipi Livni's disingeuous calls for a "code" on all democracies.
I don't have a string of letters following my name, and so I am not qualified to make clinical judgements. But it seems to me that for a brief period, at least, following the attacks of September 11, 2001, Israeli Prime Minister Ariel Sharon went crazy.
On October 4, 2001, Sharon made a speech – more of a rant, really – which literally shocked official Washington. He attacked US efforts to generate support among Arab countries for the coming war on terror. "Do not try to appease the Arabs at our expense," he said. "Israel will not be Czechoslovakia."
To president George W. Bush and his cabinet, preoccupied by imminent hostilities in Afghanistan, and preparing to lead a hoped-for international coalition against terrorism, the raw, emotional words from the Israeli leader comparing a US president to Nazi appeaser Neville Chamberlain came like a bolt out of the blue. The following day, the Israeli leader launched the heaviest Israeli military incursion into Palestinian-controlled areas since the start of the second Intifada the year before, effectively ending a cease-fire only recently agreed with PLO Chairman Arafat. As secretary of state Powell remarked at the time, "Sharon's behaviour in the last few days borders on the irrational."
But to those familiar with the workings of Sharon's fevered mind, and with the history of US-Israel relations more generally, there was a clear explanation for these outbursts. For decades, the only international relationship which has mattered to Israel has been its tie with the US. So long as America can be kept on-side, the thinking has gone, Israel can withstand any pressures, regional or international. Critical influence over US policy, then, is not something to be left to chance. And in the aftermath of the most devastating surprise-attack on the US since Pearl Harbor, when US policy was entering a period of rapid transition, there was no telling what the US might do.
Democracy as a threat
It was clear in the aftermath of 9/11 that if the US were to take effective action against Islamically-inspired terrorism, it would need to seek the support of Muslim countries to demonstrate that it was not engaging in a war against Islam. There was talk at the time of plans to launch a new Israeli-Palestinian peace initiative to be announced at the UN; there was even talk of US support for a Palestinian state. In the days following 9/11, defence secretary Rumsfeld made a quick tour of key Middle East countries seeking support; he did not bother to stop in Tel Aviv. In such an atmosphere, for those of Ariel Sharon's turn of mind, paranoia was the order of the day. Even if most Americans were not yet "connecting the dots", Sharon was seized of the guilty knowledge that it was his and Israel's continuing repression and occupation of Palestinian lands which lay near the heart of Al Qaeda's appeal for Muslims. He explained his thinking at the time to the Israeli newspaper Yedioth Ahronoth:
"There is a moment when you discover things are being done behind your back. I decided, this far and no more. A war is soon to begin. Israel will be asked to make excessive concessions to the Palestinians. Should it refuse, it will be accused of undermining the war. It was the last possible moment [to act]."
I was reminded of this brief, long-forgotten chapter in US-Israeli relations just a few days ago, when I came upon an op-ed in The Washington Post authored by Israeli politician Tzipi Livni, penned in reaction to the "democratic revolutions" taking hold in the Arab Middle East. Few Americans, I'm willing to bet, are equipped to understand the Israeli leader's words, or the fears which lurk behind them.
Once again, US policy in the Middle East appears to be at an inflection point. Indeed, the history of the entire region is at an inflection point. And once again, a US president is expressing a dangerous degree of solidarity with the aspirations of the Arabs. The US administration has even indicated that there is a place for participation by the Muslim Brothers in a democratic Egypt and, one presumes, a place for democratic participation by Islamists elsewhere as well. If Ms. Livni provides us any indication, Israeli leaders are again experiencing a period of fear and trepidation not unlike that which gripped Ariel Sharon nearly 10 years ago.
Well they might be concerned. The future direction and ultimate outcomes of the revolutionary forces unleashed in the region remain very much to be seen. But to those who suppose that Israel's greatest perceived threat in the region is a descent into political chaos and an increase in regional terrorism – well, I would advise them to read Ms. Livni's column carefully. For once one has stripped away the self-serving cant and deciphered the coded language, it becomes clear that what the leader of the Kadima party – and, one presumes, other Israeli political leaders as well – fear most in the region is…democracy itself.
It is important to remember that Israel has never wished to see democracy among the Arabs, whether in Palestine or anywhere else. Given the opportunity to exert pressure in favour of Palestinian democracy after the Oslo Accords, for example, the Israelis did much the opposite: Far better to deal with leaders relatively immune from popular pressures, with whom cynical deals could be cut, rather than with genuine politicians who are constrained to be responsive to their constituencies.
For a putative democratic leader to simply come out against Arab democracy before an American audience, however, would be rather awkward, to say the least. But there is too much at stake here for Israel, to do nothing: In Livni's own words, "…mere anxiety is not a policy for any leader". Moreover, Israel is not about to repeat its "mistake" of 2006, when it allowed Palestinian elections to go forward, and had to exert great ex-post-facto efforts to undermine their results once the wrong party – Hamas – had won them.
No, this time Tzipi Livni has a far more clever idea: To delegitimise those parties whose presence it finds inconvenient before they can ever participate in an election. The solution? International acceptance of a "universal code for participation in democratic elections". Under this scheme, every party hoping to contest elections would first have "to embrace, in word and deed, a set of core democratic principles: the renunciation of violence and the acceptance of state monopoly over the use of force, the pursuit of aims by peaceful means, commitment to the rule of law and to equality before the law, and adherence to international agreements to which their country is bound."
Livni's transparent expectation is that Islamist parties, in particular, would not be able to meet these criteria, and that any Arab country coming dangerously close to genuine democracy would be put on notice "that electing an undemocratic party would have negative international consequences." In short, if Israel were to hoodwink, say, the US and the EU into accepting these "democratic principles," it would not have such a hard time subjecting Islamist parties to the Hamas treatment, delegitimise the entire democratic process, and help ensure America's continued alienation from the Arab world – which, in the end, is precisely the point.
An inconvenient truth
Of course, there is one small inconvenience in these proposed international criteria for acceptance as a genuinely democratic party: The vast majority of Israeli parties, and certainly Livni herself, could not meet them. "Renunciation of violence…and the pursuit of aims by peaceful means"? Given Israel's past use of violence in pursuit of its interests, surely Livni cannot be serious. But let's take a moment here to consider more carefully the issue of violence. My own country came into being as a result of a violent revolt against perceived repression and abuse of inalienable rights.
Violence? The US has never hesitated to employ violence itself or to support those employing it on their own behalf in legitimate self-defence or in resistance to oppression – and quite properly so. However, all too often, the US, at least where Israel is concerned, has allowed opposition to terrorism to be conflated with opposition to the use of violence. On the contrary, opposition to terrorism is opposition to the illegitimate use of violence against innocent non-combatants. To oppose terrorism is by no means to oppose legitimate resistance to oppression.
I happen to believe that Palestinians are best advised not resort to violence, simply because in the context of their struggle, non-violent resistance, properly applied, would serve their cause far better than resort to violence. I'll gladly compare counter-terrorism credentials with anyone – but certainly have no objection in principle to the use of violence in legitimate resistance to an oppressor.
Renunciation of violence and acceptance of state monopoly over the use of force are legitimate demands of political actors within a state, but that is hardly Livni's concern here. When Israelis demand renunciation of violence, what they really mean is that others must accept their right to abuse Palestinians with impunity.
And what of "commitment to the law and to equality before the law"? Let's remember that it was Livni who was revealed in the Palestine Papers to insist repeatedly that Israel's Arab citizens should in fact be considered Palestinians, and who made clear that given the opportunity to do so, if an agreement on a two-state solution were ever reached, she would support negotiated adjustments to Israel's borders designed specifically to disenfranchise Israeli Arabs and transfer them, without their consent, to a Palestinian state. So much for equality before the law.
And finally, regarding adherence to international agreements: Again, can Livni be serious, given Israel's blatant contempt for a long string of UN resolutions applied to it, dating back to the beginning of its existence and extending over many decades? As for adherence to agreements "in word and deed", who can forget Israeli leaders' systematic refusal to meet the terms of the Oslo Accords, in spite of their nominal acceptance of its obligations?
These are but the early days of a hoped-for transition to democracy in a significant part of the Arab world. There is much that can go wrong, and many reasons for pessimism. But as the process moves forward, the US should beware the advice of putative friends whose interests do not nearly coincide with America's. This cynical and disingenuous essay from a prominent Israeli politician is but an early salvo in what promises to be a long Israeli campaign to undermine US support for Arab democratisation. US politicians should understand the motives which lie behind these efforts, and resist them at all cost.
Robert Grenier was the CIA's chief of station in Islamabad, Pakistan, from 1999 to 2002. He was also the director of the CIA's counter-terrorism centre.
Go to Original – aljazeera.net
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We found 4 hematologists who accept Humana Bronze HMO near Troy, OH.
Dr. Mohan Nuthakki is a physician who specializes in adult hematology, adult oncology, and medical oncology. He has a special interest in cancer. His professional affiliations include Good Samaritan Hospital, Kettering Health Network, and Upper Valley Medical Center. Dr. Nuthakki studied medicine at Osmania Medical College. For his residency, Dr. Nuthakki trained at a hospital affiliated with SUNY Downstate Medical Center. Dr. Nuthakki accepts several insurance carriers, including Amerigroup, Anthem, and Blue Cross/Blue Shield. He is not accepting new patients at this time.
Clinical interests: Cancer
Dr. Ronald Setzkorn is a specialist in radiation oncology and hematology (blood disorders). Dr. Setzkorn's clinical interests include cancer. He honors Anthem, Blue Cross/Blue Shield, and Coventry, in addition to other insurance carriers. Before performing his residency at a hospital affiliated with Johns Hopkins University, Dr. Setzkorn attended Thomas Jefferson University, Jefferson Medical College for medical school. He is affiliated with Good Samaritan Hospital, Atrium Medical Center, and Kettering Health Network. New patients are welcome to contact Dr. Setzkorn's office for an appointment.
Clinical interests: Cancer
Dr. Rajeev. Kulkarni is an adult hematology, adult oncology, and medical oncology specialist. Areas of expertise for Dr. Kulkarni include cancer. He is affiliated with Kettering Health Network and Upper Valley Medical Center. Dr. Kulkarni is an in-network provider for several insurance carriers, including Amerigroup, Anthem, and Blue Cross/Blue Shield. Dr. Kulkarni is open to new patients. Before completing his residency at Lankenau Medical Center, Dr. Kulkarni attended medical school at Seth G.S. Medical College.
Clinical interests: Cancer
Dr. Joseph Lavelle is a specialist in adult hematology and adult oncology. He has a 4.0 out of 5 star average patient rating. Dr. Lavelle takes several insurance carriers, including Humana HMO, Humana Bronze, and Humana Catastrophic. He is a graduate of Ohio University College of Osteopathic Medicine. He is affiliated with Kettering Health Network.
Conditions / Treatments
New Patients
Medicare Patient Conditions
Additional Information
Online Communication
Practice Affiliation
Medical School
Years Since Graduation
- Anemia, a low level of red blood cells
- Low levels of white blood cells or platelets
- Bleeding disorders, such as hemophilia
- Clotting disorders, such as deep vein thrombosis
- Cancers of the blood, such as leukemia and lymphoma


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In Theaters Apr 19
An American Running Story
Following the tragic events of 2013, BOSTON records the preparations and running of the 118th Boston Marathon one year later, when runners and community gather in support of one another for what will be the most meaningful race of all. BOSTON is more than a running documentary, it is a timeless story about triumph over adversity for runner and non-runner alike.
This one-night event also features footage of the Boston Symphony Orchestra recording an original score composed by 4X Emmy Award®-winner Jeff Beal (House of Cards).
LA Roma Films is proud to partner with John Hancock Financial, The Kennedy/Marshall Company and The Boston Athletic Association
Run Time: 2 hours 20 minutes
Categories: Sports


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dc.contributor.author | Järvinen, Joel | |
dc.date.accessioned | 2011-11-01T12:20:25Z | |
dc.date.available | 2011-11-01T12:20:25Z | |
dc.date.issued | 2011 | |
dc.identifier.uri | http://urn.fi/URN:NBN:fi:jyu-2011110111617 | en |
dc.identifier.uri | http://hdl.handle.net/123456789/36885 | |
dc.description.abstract | The stature of marketing communications function is under a threat within the firms. As the board of management tends to demand the profitability of all business activities, marketing practitioners have for a long time been unable to credibly show the link between marketing communications actions and financial value. Fortunately, the digitalization has offered new insights and opportunities to make the marketing communications actions more measureable. "Everything can be tracked" is an often heard slogan when speaking of monitoring web users' online behavior facilitated by web analytics software. However, it is questionable how well this slogan fits the marketing communications of Business-to-business (B2B) industrial companies that tend to stress the role of personal selling in their marketing communications activities. This study investigates how B2B industrial companies measure the impacts of marketing communications actions in the digital age. In particular, it aims at describing the current marketing communications measurement process and examining if the digitalization has reformed the measurement practices in a way or another. As it is often argued that the marketing practitioners are required to show the results of their activities, this study examines also the reporting and feedback processes between the marketing communications function and the top management. The main findings of this study reveal that the case companies do not measure their marketing communications results systematically, nor report them regularly to the top management. In particular, the measurement is not widely based on strategic marketing communications goals, there is no explicit metrics system in use and the top management has not set clear criteria to guide the measurement and reporting practices. However, it is found that the digitalization has facilitated the measurement practices in terms of evaluating the visibility and attractiveness of online marketing communications actions. Nevertheless, the results suggest that the digitalization has not yet revolutionized the marketing communications measurement process of B2B industrial companies, even though the future might be different. | |
dc.format.extent | 135 s. | |
dc.language.iso | eng | |
dc.rights | This publication is copyrighted. You may download, display and print it for Your own personal use. Commercial use is prohibited. | en |
dc.rights | Julkaisu on tekijänoikeussäännösten alainen. Teosta voi lukea ja tulostaa henkilökohtaista käyttöä varten. Käyttö kaupallisiin tarkoituksiin on kielletty. | fi |
dc.rights | openAccess | fi |
dc.subject.other | Marketing communications | |
dc.subject.other | Measurement | |
dc.subject.other | Digitalization | |
dc.subject.other | Goals | |
dc.subject.other | Strategies | |
dc.subject.other | Tactics | |
dc.subject.other | Reporting | |
dc.subject.other | Business-to-business industrial companies | |
dc.title | The impact of digitalization on marketing communications measurement process : case of global B2B industrial companies | |
dc.type | Book | en |
dc.identifier.urn | URN:NBN:fi:jyu-2011110111617 | |
dc.subject.ysa | markkinointiviestintä | |
dc.subject.ysa | yritysmarkkinointi | |
dc.subject.ysa | digitalisoituminen | |
dc.subject.ysa | tavoitteet | |
dc.subject.ysa | strategia | |
dc.type.dcmitype | Text | en |
dc.type.ontasot | Pro gradu | fi |
dc.type.ontasot | Master's thesis | en |
dc.contributor.tiedekunta | Jyväskylän yliopiston kauppakorkeakoulu | fi |
dc.contributor.tiedekunta | Jyväskylä University School of Business and Economics | en |
dc.contributor.yliopisto | University of Jyväskylä | en |
dc.contributor.yliopisto | Jyväskylän yliopisto | fi |
dc.contributor.oppiaine | markkinointi | fi |
dc.date.updated | 2011-11-01T12:20:25Z |


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BREEAM 2014 UK New Construction Assessor Training - This event has already finished (alternative dates are available)
BRE Wales
This is a four day course which incorporates all building types covered under the BREEAM New Construction 2014 scheme and is for New Assessors ONLY. The examination day takes place approximately 4 weeks after the initial 3 day training course.
Alternative dates
Date | Venue | Availability |
6 - 8 June | BRE Scotland, Glasgow | Available |
4 - 6 July | BRE Wales, Swansea | Available |
Are you interested in sustainable buildings, looking for a new career or adding to your current portfolio to improve the quality of the built environment? If so, we are running a four day training course (including examination) on BREEAM UK New Construction 2014, the standard for new non domestic buildings. BREEAM is the world's leading environmental assessment methodology. The training will introduce you to BREEAM, and the assessment process.
Delivered through a mixture of pre-course learning, presentations, workshops and exercises, delegates will be taken on a journey through the BREEAM assessment process gradually building up their knowledge and confidence towards becoming an assessor.
Successful delegates will emerge qualified to undertake BREEAM assessments of new non domestic buildings leading to BREEAM certification.
Key learning outcomes from the course:
- Understanding the role of the assessor
- Approaching assessment with the mind-set of an assessor
- The technical aspects of assessing the sustainability of a Non domestic building using BREEAM
- The assessment process and support structures in place for the scheme and assessors
Day 3 will be based in a computer suite as delegates undertake interactive training and exercises on using the BREEAM calculator tools.
Approximately 4 weeks after the inital 3 day training course delegates shall attend an examination day and undertake the BREEAM UK New Construction 2014 competent persons examinations. Delegates are required to bring photo ID with them on this exam day.
This course requires completion of pre-course work that will form the basis of the classroom training; therefore the last booking date for this course will be one week prior to the course commencing to allow delegates enough time to complete this pre-course work.
This scheme uses calculation tools which run in MS Excel with macros. Macintosh computers are unable to use this function and you will need access to a PC to complete assessments.
Course fee
The course fee includes all material including a copy of the BREEAM UK New Construction 2014 technical guide and the exams. All candidates completing the course will receive a CPD certificate.
- The price of the four day course is £1995 plus VAT (including the examinations)
- If you wish to become a licensed assessor please contact us at email@example.com for our licence fees
Lunch and refreshments are included in the price.
BREEAM UK New Construction 2014 Examination
To qualify as a BREEAM assessor you will need to complete and pass the two examinations taken in succession on the fourth day. Please note that it is a requirement that once qualified your organisation must hold a BREEAM licence agreement in order to offer and carry out BREEAM assessments. A copy of the BREEAM Licence Agreement is available from firstname.lastname@example.com. Licenses are grouped into Public, Commercial,Multi-residential and "Other" you will be required to hold the correct licence to assess a particular building type.
Please note that once qualified, to offer and carryout BREEAM assessments through to certification you or your organisation must hold the relevant BREEAM licence. To become licensed, all assessors/assessor organisations are required to hold a minimum level of professional indemnity insurance. Furthermore, depending on the scheme chosen, there may be an annual fee payable to BRE Global to hold the required BREEAM licence. For more information please see our FAQ page or contact us at firstname.lastname@example.com
Intended audience
This course is suitable to those individuals who are:
- Designing or specifying buildings for low environmental impact
- Delivering BREEAM environmental assessments, and
satisfying professional CPD requirements and gaining a recognised qualification at the same time.
Download Booking Form
For more information:
BRE Academy Scotland
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Prices, promotions, styles, and availability may vary. Our local stores do not honor online pricing. Prices and availability of products and services are subject to change without notice. Errors will be corrected where discovered, and Lowe's reserves the right to revoke any stated offer and to correct any errors, inaccuracies or omissions including after an order has been submitted.
Charlotte Pipe 3-in x 2-in dia Wye Cast Iron Fitting
Item # 776150 Model # NH 00021A 0800
Product Information
Type | Wye |
Sub Type | No hub |
Flexible | No |
NSF Safety Listing | Yes |
Common Uses | DWV (Drain, Waste and Vent) |
Code Approvals | 00016 ASTM A 74 |
Minimum Working Temperature (Fahrenheit) | 32 |
Maximum Working Temperature (Fahrenheit) | 212 |


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Nets' Pierce has broken hand, out 2-4 weeks
Credit: The Associated Press
NEW YORK — Paul Pierce will be out two to four weeks with a broken bone in his right hand, the biggest loss yet for the injury-plagued Brooklyn Nets.
Pierce has been diagnosed with a non-displaced fracture of the third metacarpal of his right, shooting hand, the team said Monday. He was hurt Friday in the first half of a loss at Houston.
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Keep It Simple, Stupid | |
PerlMonks |
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Pari's lift function "lifts" a modular residue back into the integers.
Presumably it is available from the Math::Pari bindings somehow (I only know pari, not the Perl bindings). blokhead In reply to Re: Using modular numbers with Math::Pari
by blokhead


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Reversible 2D/3D Coatings from Zipper-Assembly of Block Copolymer Micelles
Version of Record online: 10 JUN 2013
DOI: 10.1002/adma.201300631
Copyright © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
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How to Cite
Tyagi, P., Raschip, I. E., Deratani, A. and Quemener, D. (2013), Reversible 2D/3D Coatings from Zipper-Assembly of Block Copolymer Micelles. Adv. Mater., 25: 3739–3744. doi: 10.1002/adma.201300631
Publication History
- Issue online: 12 JUL 2013
- Version of Record online: 10 JUN 2013
- Manuscript Revised: 12 MAR 2013
- Manuscript Received: 6 FEB 2013
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Mapping has already become one of the most competitive arenas online — a visual version of local search. Barry posted earlier about how Microsoft wants to enable dynamic updating of online maps with traffic and other local data in real time. Last week, as I posted on my blog, the company announced the well-known acquisition of Vexcel corporation. Vexcel is a "remote sensing" and mapping company that enables, among other things, extremely high resolution aerial photography and 3-D mapping.
Microsoft is investing very heavily in maps and map-related technology. It sees mapping as an opening in its struggle against Google and now considers itself the technology leader in mapping. Virtual Earth, like Google and Yahoo!, has an API and the company is starting to license its product to companies like Zillow and YellowPages.com. Google remains ?ahead? in terms of the proliferation of its maps and use of its API. (According to Philipp Lessen, Google has started serving AdWords in Google Earth.)
Because of the importance of mapping both "generically" to consumers and as an entry point for local search, neither Google nor Yahoo! can afford to allow Microsoft to break out in this area. Thus I would expect to see more investment and an acceleration of product development in the near term.
Related reading
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According to The NPD Group, many retailers could struggle to make the entire holiday shopping season a successful one compared to 2015.
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Once the holiday rush is over and sites are no longer on lockdown, its time to focus on the little things adjustments, but together can produce measurable local SEO gains. Here's how to get started.
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Google adds real-time data to its Popular Times tool in Search and Maps
You can now check whether a shop, bar or restaurant is busy right at this very moment with Google's new real-time view.


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Listening Wizard helps you to improve your listening and comprehension skill. Using multimedia files(MP3 or WAV), you can work on listen-and-write and listen-and speak practice on foreign languages. You can adjust the play rate, repetition numbers to ... OS: Windows
Listening Singing Teacher is a Home Singing course. To learn to sing you need someone who guides you. As the name implies Listening Singing Teacher does just that. The program listens to you, analyzes your performance and gives you feedback on your singing ... OS: Mac
User friendly program for listening to online radio stations. Playlist support: PLS, M3U, ASX, WPL, WAX, WMX Audio format support: MP3, WMA, OGG and AAC(+) Arrange the layout of the application Save you favorite radio stations and manage them easily. OS: Windows
Counterpoint is a listening game that plays many songs from your iTunes library at once. As you guess correctly what songs are playing, they stop one by one. If you can guess them all, then you win. Your score is determined based on 4 factors: elapsed ... OS: Mac
PlayPod is new Cocoa RSS-podcast client for browsing, listening and downloading podcasts (the audio equivalent of blogs). After you download a file, you can have it move automatically to iTunes, set genres, playlists and convert to AAC bookmarkable ... OS: Mac
This AppleScript collection contains three scripts : - One will set your iChat message to the current song you are listening to. - Another will do the same, but will display that you are listening to nothing if you are listening to a song you dont ... OS: Mac
This AppleScript Collection contains 4 scripts that will calculate how much time you have spent listening to your music. There are four different ways to customize the calculation. Freeware.. OpenSoft Development: DiggUpdate. OpenSoft Development ... OS: Mac
LESEN 2000 is an educational software that makes it easy to develop listening, reading and writing skills in German. 31 fun games with hundreds of spoken and written words, puzzles, quizzes, pictures and electronic flashcards provide long-term motivation. OS: Linux , Mac , Windows
There are four diagnostic methods, namely, inspection, listening and smelling, inquiring and palpation. Four diagnostic methods are the four approaches to understand the pathological conditions. As human body is an organic entity, its regional pathological ... OS: Windows
Listening Music Teacher at www.listening-music-teacher.com helps you to understand and get the feeling for our Western music system. The Western music system is based on natural overtones. The equal tempered scale was derived from the Just intonation ... OS: Mac
Sing Along tracks what you are listening to and fetches and displays the lyrics to the song in a safari tab so that you can sing along! OS: Mac ,
Listening To displays a notification whenever a track starts playing in iTunes or Spotify so you see the track's title and artist as soon as it starts. The notification remains in the Notification Center while the track is playing so you can check out ... OS: Mac
Please enjoy 5 sets of HSK5 old exam papers in listening as well as superior voice quality. The unique assistant system will urge you to study effectively. Both learning time and accuracy are crucial to your grades. Assistant will set suitable task ... OS: iOS ,


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If Charlie Parker Was a Gunslinger,
There'd Be a Whole Lot of Dead Copycats
Containing Multitudes Since 2004
From 'The Black Panther Coloring Book' #4
"The Black man in Africa had strong warriors and beautiful cities."
2 comments:
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Yeah, sure they did.
September 21, 2005 1:32 PM
man, i love this drawing!
September 26, 2005 12:55 PM
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We've got 1 definition for NAADC »
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Amongst the casino games found at online casinos around the world the real money online slots are the most popular. There are many reasons for their popularity that include the many different themes and styles of the games together with the many different bonus options both on screen and off screen that the games offer. There are three reel slots, five reel slots and progressive slots, in some cases players can even find 7 reel slot games to play. The three reel slots offer single payline games and multiple payline games with many different features that include nudges, bonus trails, shifts and holds together with wild symbols that can take the place of other symbols to make up winning lines. The video slots also known as five reel slots, offer many more paylines per game with more complex bonus games that take place on and off screen. These bonus games include free spins, pick and win bonus choices, bonus wheels and interactive multi level bonus games. All of these real money slots can also be played for fun or practice; only the progressive games cannot be played for fun or practice because they are linked to other casinos offering the same games.
Tag Archives: visual illusions
Tripp Psychedelic Art for iPad Casino Optical Illusions Showcase
Since the advent of online casino games more than a decade ago, people have been able to play first-rate casino games for real money on their own computers in the comfort of their homes or offices. When Apple launched the iPhone, kicking off the smart phone revolution, people began to use their mobile phones to play casino games, freeing them from the dependence on the computer. The iPhone casino quickly appeared to provide the same quality casino action, specially designed for the smaller screen of the mobile phone. Now, with the widespread popularity of the iPad over recent years, the two forms – online and mobile – have essentially been united in the iPad casino, which offers the best elements of both systems. People get the same quality casino games and the ability to play for real money, and they can play them on the move on their or iPad or iPad2. They also get the bigger screen of the iPad, so there is loss of quality because of the size of the playing area. People also like the touch controls of the iPad, making it easier to play the games, adding to the enjoyment of the experience.


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Cabot Woman's Weight Loss Story Provides Hope to Others
KLRT Fox 16 Little Rock
May. 28, 2014. 10:23 PM EST
CABOT, AR -- Rebecca Privitera thought she would be overweight her entire life. When she was in J... More »
CABOT, AR -- Rebecca Privitera thought she would be overweight her entire life. When she was in Jr. High school she could only wear plus-size clothing because she weighed over 200 pounds. After she graduated, it only got worse. She ballooned to 381 pounds and her health got worse. At the age of 16 she was hospitalized with a blood clot, but that didn't stop her from eating fast food for breakfast, lunch and dinner. As she got older, her blood pressure skyrocketed and she was forced to take three different medications to treat it. She also became depressed. Her doctor told her that she could "stroke out" if she wasn't careful, so she was put on bed rest for six weeks. "I can remember sitting at home and eating Sonic and things like that and seeing everybody around me having a good time, but I honestly thought that that wasn't the lifestyle I was supposed to have. So I just kind of let life pass me by," said Privitera. The turning point in her life came in May of 2011, when her mother-in-law talked her into doing a 5k race. "I wanted to quit the whole time. It took me an hour and 14 minutes and I finished in last place. I was just ashamed that I was 29 and in such poor health." But instead of going home and returning to a life of sitting on the couch, she pulled out an old workout video she had purchased. "I was like, well, we got to start somewhere." It wasn't easy, but eventually she made progress. The workout video led to her going out and walking, even if it was just for ten minutes. She then started doing the elliptical machine. But she didn't stop there. She bought even more workout videos and started eating healthier foods. And to keep her motivated, she posted her progress on Facebook for everyone to see. "Weight loss is really hard for anybody; no matter if it's 20 pounds, 50 pounds or more, it's hard. So, the more encouragement I got, the more I wasn't afraid to show people what I was doing." Her determination and dedication paid off. "I didn't make a deadline for this. So I started in June of 2011 and I lost the first 112 pounds within a year. I lost the next 100 pounds within another year and then I lost another 60 on top of that," said Privitera. In a span of nearly three years, she lost a total of 221 pounds. "My goal was to just get under 300 pounds, so to be standing here today at 160 pounds, I'm pretty excited." Her journey resulted in huge following too. In addition to her Facebook posts, Rebecca posted her progress on Instagram and now has 20,000 followers. She also posted her story on Team Beach Body's website, the same company she bought her workout videos from. As a result of her story, she won a number of contests including a monthly contest in which she won $1,000. She then won a quarterly challenge. Now, she's one of four finalists in a national competition in which the public votes. If she wins, she gets $100,000. Since losing all that weight, Rebecca has run a number of races, including two half-marathons. She also decided to return to the site of her first 5k. She finished in just over 34 minutes! She's now a licensed trainer and certified in Turbo Kick. Her goal is to lose ten more pounds. But she also wants to help teens and young adults who are still struggling with being overweight. "You don't realize how far you've come without looking back to where you were." And where she was- is a place she never wants to return to- or forget. « Less
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Sleeps | 8 |
Bedrooms | 3 |
Bathrooms | 2 |
Half Baths | 1 |
Property type | house |
Minimum Stay | 3 nights |
Charming New Smyrna beachfront home. Come and enjoy beautiful sunrises and sunsets from the spacious deck. Dolphins frequently swim by to say hello and you can walk to nearby Manatee park where manatees frequent much of the year. Manatee park also offers tennis, volleyball, basketball, and a new play set for the kids. Surf or river fish till your hearts content.
House is located in the middle of the block and is half a mile away from public parking to the south and three miles from public parking to the north, so this beach not only is VERY PRIVATE, but also CAR FREE. You have your own personal dune walkover to enjoy your little slice of heaven. Canaveral National seashore is two miles to the south and full of wildlife, hiking, boating, etc.
3 br/2.5 bath has downstairs large bedroom with two queen beds, full bath and a family room with a TV and VCR/DVD player. Upstairs is a master bedroom with a king-size bed & full bath, 2nd bedroom has daybed (2 twins).
Loved the view from the deck! It was a great place to watch the sunrise. The house was very nice and has everything you need for enjoying days on the beach. Have already recommended house to friends. Very prompt response from owner. Many restaurants to chose from but have to say we do Love JB's Fishcamp which is only a mile down the road.
we felt like we had our own private beach... the house was lovely. the view delicious. The owner definately went all out to ensure our stay was all it could be. Just little touches that we havent found at other rentals. We cant wait to stay again. LOVED IT !!!!!! we have shown pictures to all our friends and they couldnt get over the views and space.
We would recommend eating at he Upper Deck defo if you like good food and wine. The Garlic , delish, and for an all you can eat fish fry, fish was yummy!! Flip Flops restaurant...
Manatee park just down the road is a must. to see wild Manatees and dolphins that close is amazing.
Hope you come and stay, you definately wont be disappointed.
We stayed the week. House was ideal. Right on the beach. Location was peaceful, but close to attractions and town.
New Smyrna Beach is a quiet little beach town with great restaurants and lots of charm! There is the ocean, arts, shopping, fishing, and many other outdoor activities. It is about 1 hour from Orlando and all it's attractions including Disney, Universal, etc. and is also about 1 hour from Kennedy Space Center. Time your visit to the Space Shuttle launch and enjoy the breathtaking launch from the deck, or from the beach! This beach is at least 1/2 mile from any public parking lots and is essentially private, even in busy months. No cars can reach you and the sea turtles will welcome you to their nesting grounds!
Rate Period | Nightly | Weekend Night | Weekly | Monthly | Event | ||||
My Standard Rate
3 night minimum stay
Pet Fee | $150 |
Tax Rate | 12.5% |


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Non-Mendelian Inheritance Mitochondria Chloroplasts Examples of non-Mendelian inheritance Human mtDNA defects Other forms of non-Mendelian Inheritance: Infectious cytoplasmic inheritance Maternal effect Genomic (parental) imprinting
Extranuclear Genomes: Mitochondria (animals and plants) Chloroplasts (plants) 1.Mitochondria and chloroplasts occur outside the nucleus, in the cytoplasm of the cell. 2.Contain genomes (mtDNA/cpDNA) and genes, i.e., extrachromosomal genes, cytoplasmic genes, organelle genes, or extranuclear genes. 3.Inheritance is non-Mendelian (e.g., cytoplasm typically is inherited from the mother).
Origin of mitochondria and chloroplasts: Both mitochondria and chloroplasts are believed to be derived from: Endosymbiotic bacteria = free-living prokaryotes that invaded ancestral eukaryotic cells and established a mutually beneficial relationship. 1.Mitochondria - derived from a photosynthetic purple bacterium that entered a eukaryotic cell >billion years ago. 2.Chloroplasts - derived from a photosynthetic cyanobacterium.
Organization of the mtDNA genome: mtDNAs occur in all aerobic eukaryotic cells and generate energy for cell function by oxidative phosphorylation (producing ATP). Most mtDNA genomes are circular and supercoiled (linear mtDNAs occur in some protozoa and some fungi). In some species %GC is high, allowing easy separation of pure mtDNA from nuclear DNA by gradient centrifugation. mtDNAs lack histone-like proteins (like bacteria). Copy number is high, multiple genomes per mitochondria and many mitochondria per cell (makes mtDNA easy to isolate and PCR). Size of mtDNA varies widely. Humans and other vertebrates~16 kb (all of the mtDNA codes gene products) Yeast~80 kb Plants~100 kb to 2 Mb (lots of non-coding mtDNA)
Replication of the mtDNA genome: Replication is semi-conservative (like nuclear DNA replication) and uses DNA polymerases specific to the mitochondria. Occurs throughout the cell-cycle (not just S phase). Control region (non-coding) forms a displacement loop (d-loop) that functions in mtDNA replication. Mitochondria (organelle) are not synthesized de novo, but grow and divide like other cells (e.g., mitosis).
Fig. 23.3, mtDNA replication
Contents of the mtDNA genome: mtDNA contains genes for: tRNAs rRNAs cytochrome oxidase, NADH-dehydrogenase, & ATPase subunits. mtDNA genes occur on both strands. Functions of all human mtDNA ORFs are assigned. Mitochondria ' s genetic information also occurs in the nuclear DNA: DNA polymerase, replication factors RNA polymerase, transcription factors ribosomal proteins, translation factors, aa-tRNA synthetase Additional cytochrome oxidase, NADH, ATPase subunits. Most required mitochondrial (and chloroplast) proteins are coded by nuclear genes in the nuclear genome. Copies of the true mtDNA genes can be transposed to the nucleus (a distinct set of genes from above): numtDNA = nuclear mtDNA
Fig. 23.4, Physical map of the human mtDNA
Transcription of the mtDNA genome: mRNAs from the mtDNA are synthesized and translated in the mitochondria. Gene products encoded by nuclear genes are transported from the cytoplasm to the mitochondria. Mammalian and other vertebrate mtDNAs are transcribed as a single large RNA molecule (polycistronic) and cleaved to produce mRNAs, tRNAs, and rRNAs before they are processed. Most mtDNA genes are separated by tRNAs that signal transcription termination. In plants and yeast (mtDNA is much larger): tRNAs do not separate genes Gaps between genes are large Transcription is signaled by non-tRNA sequences Introns occur (do not occur in animal mtDNA) Some lack a complete stop codon (3 ' end is U or UA; poly (A) tail completes the stop codon) Transcription is monocistronic
Translation of the mtDNA genome: Mitochondria mRNAs do not have a 5 ' cap (yeast and plant mt mRNAs have a leader). Specialized mtDNA-specific initiation factors (IFs), elongation factors (EFs), and release factors (RFs) are used for translation. AUG is the start codon (binds with fMet-tRNA like bacteria). Only plants use the " universal " genetic code. Codes for mammals, birds, and other organisms differ slightly. Extended wobble also occurs in tRNA-mRNA base-pairing (22 tRNAs are sufficient rather than 32 tRNA needed for standard wobble).
Useful applications of mtDNA: Easy to isolate and PCR (high copy #). Most mtDNA is inherited maternally. Can be used to assess maternal population structure (to the exclusion of male-mediated gene flow) Because it is " haploid " effective population size of mtDNA is 1/4 that of a nuclear gene. As a result, mtDNA substitutions fix rapidly (due to genetic drift) and typically show higher levels of polymorphism. Useful for: Maternity analysis Phylogenetic systematics Population genetics (and conservation genetics) Forensics (maternal ID)
Chloroplast genomes (cpDNA): Chloroplast organelles are the site of photosynthesis and occur only in green plants and photosynthetic protists, Like mtDNA, chloroplast genome is: Circular, double-stranded Lacks structural proteins %GC content differs Chloroplast genome is much larger than animal mtDNA, ~80-600 kb. Chloroplast genomes occur in multiple copies and carry lots of non- coding DNA. Complete chloroplast sequences have been determined for several organisms (tobacco 155,844 bp; rice 134,525 bp).
cpDNA organization: Nuclear genome encodes some chloroplast components, and cpDNA codes the rest, including: 2 copies of each chloroplast rRNA (16S, 23S, 4.5s, 5S) tRNAs (30 in tobacco and rice, 32 in liverwort) 100 highly conserved ORFs (~60 code for proteins required for transcription, translation, and photosynthesis). Genes are coded on both strands (like mtDNA). cpDNA translation- similar to prokaryotes: Initiation uses fMet-tRNA. Chloroplast specific IFs, EFs, and RFs. Universal genetic code.
Fig. 23.7 cpDNA of rice
Rules of non-Mendelian inheritance for mtDNA and cpDNA: Ratios typical of Mendelian segregation do not occur because meiotic segregation is not involved. Reciprocal crosses usually show uniparental inheritance because zygotes typically receive cytoplasm only from the mother. Genotype and phenotype of offspring is same as mother. Paternal leakage occurs at low levels and usually is transient; mechanisms that degrade paternal mtDNA/cpDNA exist. Heteroplasmy (mixture of mtDNA/cpDNA organelles with different DNA substitutions) results in rare cases.
Examples of non-Mendelian inheritance: Variegated-shoot phenotypes in four o ' clocks Fig. 23.8b Normal chloroplast Green photosynthetic Mutant chloroplast White non-photosynthetic Mixed chloroplasts White/green
Fig. 23.9 Chloroplasts are inherited via the seed cytoplasm 3 types of eggs (female): Normal Mutant Mixed Assumption: Pollen (male) contributes no information
Examples of non-Mendelian inheritance: Mutant [poky] Neurospora possess altered mtDNA cytochrome complements that lead to slow growth. [poky] phenotype is inherited with the cytoplasm. Fig. 23.10, Reciprocal crosses of poky and wild-type Neurospora. protoperitheca (sexual mating type) conidia (asexual mating type)
Examples of maternally inherited human mtDNA defects: Leber ' s hereditary optic neuropathy (LHON), OMIM-535000 Mid-life adult blindness from optic nerve degeneration. Mutations in ND1, ND2, ND4, ND5, ND6, cyt b, CO I, CO II, and ATPase 6 inhibit electron transport chain. Kearns-Sayre Syndrome, OMIM-530000 Paralysis of eye muscles, accumulation of pigment and degeneration of the retina, and heart disease. Deletion of mtDNA tRNAs. Myoclonic epilepsy & ragged-red fiber disease (MERRF), OMIM- 545000 Spasms and abnormal tissues, accumulation of lactic acid in the blood, and uncoordinated movement. Nucleotide substitution in the mtDNA lysine tRNA. Most individuals with mtDNA disorders possess a mix of normal and mutant mtDNA, therefore severity of diseases varies depending on the level of normal mtDNA.
Exceptions to maternal inheritance: Heteroplasmy, mice show paternal DNA present at 1/10,000 the level of maternal DNA. Occurs when mtDNA from sperm leak into egg cytoplasm at the time of fertilization. In these cases, maternal and paternal mtDNA can recombine! Paternal inheritance of chloroplasts commonly occurs in some plants (e.g., gymnosperms). www.sciencemusings.com/
Maternal effect: Some maternal phenotypes are produced by the nuclear genome rather than the mtDNA/cpDNA genomes. Proteins or mRNA (maternal factors) deposited in the oocyte prior to fertilization; these are important for development. Genes for maternal factors occur on nuclear chromosomes; no mtDNA is involved (not epigenetic). e.g., shell coiling in the snail Limnaea peregra. Determined by a pair of nuclear alleles; D produces dextral (right-handed) coiling, d produces sinistral (left-handed) coiling. Shell coiling always is determined by the maternal genotype, not the alleles that the progeny carry or maternal phenotype. If coiling were controlled by extranuclear gene (e.g., mtDNA), progeny would always have the same phenotype as mother. Cause-female snail deposits products in the egg that regulate orientation of mitotic spindle and direction of cell cleavage.
Fig. 23.17 dextral sinistral *****dextral *****
Maternal effect: mRNAs coded by maternal genes (not offspring) are essential for normal structural development and axis orientation. Placement of bicoid mRNA determines anterior end of developing Drosophila embryo. http://scienceblogs.com/pharyngula/2006/06/maternal_effect_genes.php
Genomic (parental) imprinting: Expression of genes (or alleles) is determined by whether the gene is inherited from the father or mother. Results in expression of single allele (either from father or mother); other allele frequently suppressed by methylation. Mechanisms differ between maternal effect and imprinting: Maternal effect: dextral/sinistral coiling of snail shells. Genomic imprinting: genes from one sex suppressed by methylation (Prader-Willi syndrome, OMIM-176270).
Transovarial disease transmission - a type of maternal inheritance: Infected cytoplasm infects the egg and is transmitted to offspring. Many insect-vectored diseases show transovarial transmission. Example - eggs and larvae of mosquitoes infected with West Nile Virus also are infected. http://gsbs.utmb.edu/microbook/ch056.htm
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Romantic Moments for Male Choir[CD]~ ABT / TAIPEI MALE CHOIR / ENGELS-BENZ / BERNIUSProduct Notes
Together with Frieder Bernius the multiple prizewinning singers of the Tapei Male Chor (TMC) have completed a CD recording featuring sacred works for men's choir from the turn of the 19th to the 20th century as well as from the flowering of German men's choirs at the beginning of the 19th century. The Taiwanese choir presents a masterly performance of German men's choral literature and it is admirable the way in which it is dedicated to following the diction of the foreign language and achieving the differentiated tone colors of this repertoire. Since it's founding in 1994 the Taipei Male Choir has been invited to sing at many international choir festivals and has been honored with many prestigious prizes.
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