text: This listing is no longer available or has been sold. Find Another One Others Looked At... BIG BORE 458 LOTT RIFLE BARREL SELLER: Lou's Outpost 0 $330.00 Magnum Research Desert Eagle Conversion ... SELLER: Ammo And Arms 1 $449.99 SPRINGFIELD '03 BARREL U.S.M.C. MARKED SELLER: LLEWELLYN 0 $200.00 .50 Beowulf 16" AR Platform Complete Upp... SELLER: Ridgeback 0 $1,299.99 WINCHESTER 1894 20 INCH OCTAGONAL 30-30... SELLER: JBJIM 1 $139.00 WINCHESTER 1894 26 INCH OCTAGONAL BARRE... SELLER: JBJIM 1 $175.00 Non Guns Barrels Rem Choke Tube Remington gauge Sporting Improved Cylinder SA Extended Stainless Tube . muzzle by . Back Side | 799 | 0 | Lc | 453.1284ms Rem Choke Tube Remington 12 gauge Sporting Improved Cylinder SA18619 Extended Stainless Tube .718 muzzle by .738 Back Side For Sale from Robertson Trading Post | Positive feedback: 99% View | Verified Seller | 19487 Completed Sales View Sellers Items This item is no longer available. /UserImages/87270/989315520 5704257.jpg /UserImages/87270/989315520 5704258.jpg /UserImages/87270/989315520 5704259.jpg /UserImages/87270/989315520 5704260.jpg /UserImages/87270/989315520 5704261.jpg /UserImages/87270/989315520 5704262.jpg Description Shipping and Payment More Info This listing is for ONE Choke Tube at $19.00. Buyers, however, may take six or more, minimum of a factory case of 6, and the price gets down to $11.50 apiece with no additional shipping charges. Factory Cartons contain 6 tubes, but we can ship any number we have. Photos show several factory Remington Rem-Choke tubes we came across on a distributor liquidation from North Carolina. These are all brand new in their factory packages, Remington number 18619, 12 gauge Sporting, Improved Cylinder. Our Mitutoyo Dial Calipers gauge them at .738 on their back ends beside the threads, and .718 at the muzzle end. They all have knurled extensions for quick and easy removal and replacement. We use them to replace Turkey tubes on 870 Super Mags, because many of our customers buy the Express Super Mags for protection and this tube will pattern any type of shot well, from #9 to Steel to 000 Buckshot. All of them are stainless steel. Current wholesale on Remington Extension Improved Cylinder tubes like this is over $30 apiece. Our Single Rem-Choke Tube price, however, is only $19.00. We're offering them in factory cartons of 6 at only $11.50 each, 6 or more at $11.50. Own a factory carton of 6 of these fine tubes for only $69.00. >>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>> Grips, Magazines, slings, holsters, scopes, mounts, parts & most any small light items, entire accessory orders only $10.00 total shipping no matter how many a person buys. $10.00 for an entire order, Not $10.00 per item or anything of the sort. $20 Flat Fee on magazine orders to Alaska, Hawaii, or Puerto Rico, and gun parts to PR civilians must ship to an FFL. Magazines and any small light non-gun items ride free with ammo orders. We accept checks with no more than 7 days hold. GA Pay, MC, Visa, Discover phone- or fax-in 7 3 1 9 8 9 4 7 2 3 orders, USPS Money Order items shipped ASAP please put your full information, venue number, and what the item is on any messages. Internet phone hours 8:00 – 5:00 CST Mon – Fri. Robertson Trading Post 117 Front Street PO Box 365 Henderson, Tennessee 38340. We buy, sell, and trade. Always have, since 1952. $10.00 total for an entire order lower 48. for any combination of small light items. $20 to AK, HI, or PR. Grips Magazines & all small items ride free with Gun or Ammo shipments. We Buy, Sell, or Trade. We always have. Trades Accepted: We Buy, Sell, or Trade. Always have. Don't let your buddies use your account. Registered user must be the buyer, with his or her own money. Buying firearms and related items for other people can result in felony charges. Don't try, either, to circumvent any law; for example, a California civilian may not buy a high capacity magazine and have it shipped to his brother-in-law in Nevada. That is a felony. GA Pay buyers are NOT charged until we confirm we have the item and are ready to ship it. The same thing is true for phone-in, fax-in, and mail-in payments. In this respect, and in several others, Guns America outshines all its competitors. This is the best firearms website there is, hands down. Condition: New In Box Location: TN Qty: 17 Available Share Item Item #: 989315520 Stock No.: SA18619 This item is no longer available. Price: This Seller Accepts Online Payment Shipping: $10.00 Accepted Payment Methods: Returns: No Returns Robertson Trading Post Seller Since: Jul. 2007 Seller Level: Trusted Seller This seller is an FFL City: Henderson State: TN Your Recently Viewed Items


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The cool and versatile center console Axopar 37 Sun-Top, with an extended roof for even more protection from the elements and a huge canvas section to let in large amounts of sun into the cockpit. The Sun-Top combines flexible accommodation with a versatile layout and is one of the most adaptable boats on the market, filled with practical solutions.
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50 South Bryan Rd.
Dania Beach, FL 33004
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Last Build Date: Tue, 29 Mar 2016 16:33:11 +0100
Tue, 29 Mar 2016 09:23:40 +0100
Abstract: Every year cervical cancer affects around 528000 women and causes 266000 deaths worldwide with 80% of deaths occurring in less developed countries with a concomitant 18-fold difference in mortality occurring between developed and developing countries. Cervical cancers is caused by the Human Papilloma Virus (HPV) with the oncogenic types 16 and 18 accounting for 70% of invasive disease. Other cancers associated with HPV infection include vaginal, vulvar, penile, oropharyngeal and anal cancers. (Source: International Journal of Infectious Diseases)MedWorm Sponsor Message: Directory of the best January Sales in the UK. Find the best Christmas presents too.
Tue, 29 Mar 2016 09:23:38 +0100
Background: The study highlighted factors associated with the occurrence of ano-genital warts (AGWs) among HIV infected individuals in South Africa (SA). Human Papilloma Virus (HPV) infection occurs more frequently among HIV infected individuals because of their compromised immuno-status. (Source: International Journal of Infectious Diseases)Tue, 29 Mar 2016 09:23:38 +0100
Background: The human papillomavirus (HPV) is the main cause of cervical cancer in developing countries. HPV is common in all socioeconomic groups and is spread all over the world. There are more than 100 types of HPV which are divided into high risk and low risk groups. Molecular method is one of the rapid and accurate methods to study HPV genotypes. (Source: International Journal of Infectious Diseases)Tue, 29 Mar 2016 09:23:35 +0100
Background: Almost half of penile cancers and the majority of penile warts are associated with the two HR types (HPV 16 and HPV 18) and two LR HPV types (HPV 6 and HPV 11), respectively. It is therefore important to document the burden HPV associated diseases of the penis and identify the HPV types associated with the diseases. HPV E6 and E7 mRNA detection is the best indicator of HPV status that is clinically relevant as it indicate transcriptionally active HR HPV infection in lesions. In HR HPV infection an increase in E6 and E7 mRNA expression causes an overexpression of p16INK4A and thus used as a cellular correlate of the increased expression of HR HPV E6 and E7 mRNA in cervical samples. (Source: International Journal of Infectious Diseases)Tue, 29 Mar 2016 09:23:35 +0100
Background: Cervical cancer is the most common malignancy in Indian women and approximately 130,000 women fall prey to cervical cancer every year. HPV DNA testing can be used as an adjunct to cytological screening of cervical samples of above 30 year old women and can be used as an optional test for follow-up in women who have slightly abnormal Pap test results. The aim of the study was to assess the HPV 16 and 18 status in cervical cancer patients and in healthy women visiting JIPMER, Pondicherry. (Source: International Journal of Infectious Diseases)Mon, 28 Mar 2016 19:39:01 +0100
In Denmark, the human papillomavirus (HPV) vaccination program for girls and women has been followed by a decreased incidence of genital warts in young men. Reuters Health Information (Source: Medscape Medical News Headlines)MedWorm Sponsor Message: Directory of the best January Sales in the UK. Find the best Christmas presents too.
Sun, 27 Mar 2016 22:00:00 +0100
Conclusions Changing HPV vaccine recommendations had minimal cross-gender impact. Early adoption and timely completion patterns were mostly similar across genders. (Source: American Journal of Preventive Medicine)Sun, 27 Mar 2016 22:00:00 +0100
Squamous cell carcinoma of the oropharynx (SCCOP) is a subtype of squamous cell carcinoma of the head and neck (SCCHN) [1]. In the U.S., approximately 13,510 new cases of SCCOP are diagnosed, and 2330 deaths result from these cancers, annually [2]. Although tobacco smoking and alcohol consumption remain significant risk factors for SCCOP, human papillomavirus (HPV) accounts for a growing proportion of cases, particularly in young adults [1,3]. There are more than 100 different HPV types; about 20 of these have oncogenic potential (i.e., the high-risk types) [4]. (Source: Oral Oncology)Sun, 27 Mar 2016 22:00:00 +0100
ConclusionsIn this cohort of individualsbeing treated with antiretroviral drugs, those who were MSM, who were 30–39 years old, and who had a prior history of STI, were at highest risk of a further STI diagnosis. (Source: HIV Medicine)Sun, 27 Mar 2016 12:33:04 +0100
We present a patient with HPV 70/85-positive widespread cutaneous warts characterized by clinical and histological features atypical for classic generalized verrucosis or epidermodysplasia verruciformis. The cutaneous HPV infection is characterized by verrucous papules or plaques variable in size, number, and distribution depending on the genotype of HPV involved and the immune status of the patient. Human papillomaviruses comprise five genera (alpha, beta, gamma, mu, and nu papillomavirus) with different life-cycle characteristics, epithelial tropisms, and disease associations. Epidermodysplasia verruciformis (EV) is a rare, lifelong, autosomal recessive skin disease characterized by persistent cutaneous human papillomavirus infection not necessarily associated with immune system defects...Sun, 27 Mar 2016 05:28:02 +0100
Authors: Coppock JD, Vermeer PD, Vermeer DW, Lee KM, Miskimins WK, Spanos WC, Lee JH Abstract Effective treatments for recurrent/metastatic human papillomavirus-positive (HPV+) head and neck squamous cell cancer (HNSCC) are limited. To aid treatment development, we characterized a novel murine model of recurrent/metastatic HPV+ HNSCC. Further analysis of the parental tumor cell line and its four recurrent/metastatic derivatives led to preclinical testing of an effective treatment option for this otherwise fatal disease. Reverse phase protein arrays identified key signaling cascades in the parental and recurrent/metastatic cell lines. While protein expression profiles differed among the recurrent/metastatic cell lines, activated proteins associated with the mTOR signaling cascade we...MedWorm Sponsor Message: Directory of the best January Sales in the UK. Find the best Christmas presents too.
Sun, 27 Mar 2016 05:28:02 +0100
Authors: Gu Y, Ma C, Zou J, Zhu Y, Yang R, Xu Y, Zhang Y Abstract A complete understanding of the natural history of infection with high-risk human papillomaviruses (HPVs) in cervical cancer requires data from regional and ethnic studies. The prevalence of high-risk HPVs was evaluated retrospectively in 2040 patients with cervicitis, 239 with cervical intraepithelial neoplasia grade 1 (CIN1), 242 with CIN2/3, and 42 patients with invasive squamous cell carcinoma (SCC) based on data from patients who visited our hospital between May 2013 and May 2015. The rates of high-risk HPV infection in patients with cervicitis, CIN1, CIN2/3, and invasive SCC were 40.8%, 74.9%, 70.2%, and 83.3%, respectively. The three most dominant HPV genotypes were HPV16, 58, and 52. HPV16 and HPV58 positivit...Sun, 27 Mar 2016 05:28:02 +0100
Authors: Vermeer DW, Coppock JD, Zeng E, Lee KM, Spanos WC, Onken MD, Uppaluri R, Lee JH, Vermeer PD Abstract Human papillomavirus induced (HPV+) cancer incidence is rapidly rising, comprising 60-80% of oropharyngeal squamous cell carcinomas (OPSCCs); while rare, recurrent/metastatic disease accounts for nearly all related deaths. An in vivo pre-clinical model for these invasive cancers is necessary for testing new therapies. We characterize an immune competent recurrent/metastatic HPV+ murine model of OPSSC which consists of four lung metastatic (MLM) cell lines isolated from an animal with HPV+ OPSCC that failed cisplatin/radiation treatment. These individual metastatic clonal cell lines were tested to verify their origin (parental transgene expression and define their physiologi...Sat, 26 Mar 2016 08:13:15 +0100
Conclusions: Vaginal cancer is rare, and asymptomatic low-risk women should not be screened. An algorithm based on expert opinion is proposed for managing women with abnormal vaginal test results. (Source: Journal of Lower Genital Tract Disease)Sat, 26 Mar 2016 08:13:15 +0100
Conclusions: Human papillomavirus vaccine is highly acceptable among college women, particularly among Hispanic women. Efforts to vaccinate should include time of college enrollment. Such efforts are critical for the large scale prevention of cervical cancer and its precursor lesions and ultimately for preventable cervical cancer mortality. (Source: Journal of Lower Genital Tract Disease)Sat, 26 Mar 2016 08:13:15 +0100
Conclusions: The intervention did not improve cytology test attendance, although education about HPV and cervical cancer risk as part of study procedures was associated with testing for 35% of this group of women whose previous cytology occurred an average of 3.6 years before the baseline appointment. Self-sampling for HPV testing was feasible. (Source: Journal of Lower Genital Tract Disease)MedWorm Sponsor Message: Directory of the best January Sales in the UK. Find the best Christmas presents too.
Sat, 26 Mar 2016 08:13:15 +0100
Conclusions: Women in the CM arm were less likely to complete care than women in the ST arm. Targeted outreach to underscreened women successfully identified women with higher prevalence of HPV and possibly higher disease burden. (Source: Journal of Lower Genital Tract Disease)Sat, 26 Mar 2016 08:13:15 +0100
Conclusions: With a sensitivity of 94% of the first HPV test, 6 of 100 cervical cancers will be missed if this was the only test used in a population screening program. The missed cancers were however all clinically detectable. (Source: Journal of Lower Genital Tract Disease)Sat, 26 Mar 2016 08:13:15 +0100
Conclusions: Colposcopic impressions of acetowhitening or worse are highly sensitive for identifying cervical precancers and reproducible on static image-based pattern recognition. (Source: Journal of Lower Genital Tract Disease)Fri, 25 Mar 2016 17:33:04 +0100
Authors: Ortiz-Sánchez E, Santiago-López L, Cruz-Domínguez VB, Toledo-Guzmán ME, Hernández-Cueto D, Muñiz-Hernández S, Garrido E, Cantú-De León D, García-Carrancá A Abstract Cancer stem cells (CSC) exhibit high tumorigenic capacity in several tumor models. We have now determined an extended phenotype for cervical cancer stem cells. Our results showed increased CK-17, p63+, AII+, CD49f+ expression in these cells, together with higher Aldehyde dehydrogenase (ALDHbright)activity in Cervical CSC (CCSC) enriched in cervospheres. An increase in stem cell markers, represented by OCT-4, Nanog, and β-catenin proteins, was also observed, indicating that under our culture conditions, CCSC are enriched in cervospheres, as compared to monolayer cultures. In addition, we were able to...Thu, 24 Mar 2016 23:00:00 +0100
Conclusions The cohort shows significant lower incidence of STD, most likely including human papillomavirus, which may partly explain the lower incidence of cancers of the cervix, rectum, anus, head and neck. (Source: BMJ Open)MedWorm Sponsor Message: Directory of the best January Sales in the UK. Find the best Christmas presents too.
Thu, 24 Mar 2016 18:43:02 +0100
Authors: Abstract Immunization against vaccine-preventable diseases is an essential component of women's primary and preventive health care. Despite the importance of vaccination and clear guidance from public health agencies, rates of vaccination lag behind national goals. Obstetrician-gynecologists can play a major role in reducing morbidity and mortality from a range of vaccine-preventable diseases, including pertussis, influenza, human papillomavirus, and hepatitis. Given demonstrated vaccine efficacy and safety, and the large potential for prevention of many infectious diseases that affect adults, pregnant women, and newborns, obstetrician-gynecologists should include immunizations as an integral part of their practice. To do so, they must embrace their role as important sour...Thu, 24 Mar 2016 18:43:02 +0100
Authors: Abstract Immunization against vaccine-preventable diseases is an essential component of women's primary and preventive health care. Despite the importance of vaccination and clear guidance from public health agencies, rates of vaccination lag behind national goals. Obstetrician-gynecologists can play a major role in reducing morbidity and mortality from a range of vaccine-preventable diseases, including pertussis, influenza, human papillomavirus, and hepatitis. Given demonstrated vaccine efficacy and safety, and the large potential for prevention of many infectious diseases that affect adults, pregnant women, and newborns, obstetrician-gynecologists should include immunizations as an integral part of their practice. To do so, they must embrace their role as important sour...Thu, 24 Mar 2016 15:22:23 +0100
Abstract Many skin and skin‐related diseases affect the sexes unequally, with attendant implications for public health and resource allocation. To evaluate better the incidence of skin and skin‐related diseases affecting males vs. females, we reviewed published population‐based epidemiology studies of skin disorders performed utilizing Rochester Epidemiology Project data. Females had a higher incidence of the following diseases: connective tissue diseases (scleroderma, morphea, dermatomyositis, primary Sjögren syndrome, systemic lupus erythematosus [not in all studies]), pityriasis rosea, herpes progenitalis, condyloma acuminatum, hidradenitis suppurativa, herpes zoster (except in children), erythromelalgia, venous stasis syndrome, and venous ulcers. Males had a higher incidence of ...Wed, 23 Mar 2016 23:34:13 +0100
This article proposes a compromise: cytology and HPV co‐testing for the first two screening tests to optimise the sensitivity of the test as a whole. Registrations of invasive and in situ carcinoma of the uterine cervix in England indicate that the prevalence of the disease is highest in young women in the early rounds of screening. Calculations of the likely impact on the workload of this proposal have been based on a service evaluation of 295 cytology tests received at St Thomas' Hospital, which suggests that the volume of cytology tests would be reduced by approximately 60% compared with 80% for primary HPV testing alone. This proposal should be debated openly before irrevocable changes are made to a skilled workforce. (Source: Cytopathology)Wed, 23 Mar 2016 23:00:00 +0100
Abstract Transforming growth factor β1 (TGF-β1) is a multifunctional cytokine that plays important roles in cervical tumor formation, invasion, progression, and metastasis. TGF-β1 functions as a tumor inhibitor in precancerous lesions and early stage cancers of cervix whereas as a tumor promoter in later stage. This switch from a tumor inhibitor to a tumor promoter might be due to various alterations in TGF-β signaling pathway, such as mutations or loss of expression of TGF-β receptors and SMAD proteins. Additionally, the oncoproteins of human papillomaviruses have been shown to stimulate TGF-β1 expression, which in turn suppresses host immune surveillance. Thus, in addition to driving tumor cell migration and metastasis, TGF-β1 is believed to play a key role in promoting h...MedWorm Sponsor Message: Directory of the best January Sales in the UK. Find the best Christmas presents too.
Wed, 23 Mar 2016 07:43:49 +0100
This study included 104 tissue samples from primary prostate carcinoma cases. HPV DNA was purified and then amplified using MY09/11 and GP5+/GP6+ degenerate primer sets that detect a wide range of HPV types, and with specific PCR primers sets for E6 and E7 HPV regions to detect HPV 16. None of the samples showed amplification products of HPV DNA for primer sets MY09/11 and GP5+/GP6+, or the specific primer set for the E6 and E7 HPV regions. HPV infection, thus, does not seem to be one of the causes of prostate cancer in the population studied. (Source: Genetics and Molecular Biology)Wed, 23 Mar 2016 06:00:00 +0100
(NaturalNews) A new study has found that Merck & Co., the maker of the human papillomavirus (HPV) vaccine Gardasil, neglected to examine the drug's effect on the reproductive systems of women.As a result of that neglect, as well as the inherent dangers behind the vaccine, an Australian... (Source: NaturalNews.com)Wed, 23 Mar 2016 00:17:05 +0100
By Stacy Simon The American Cancer Society has released a new Head and Neck Survivorship Care Guideline to help survivors of head and neck cancer and their primary care providers better manage their long-term care. The guideline addresses cancers of the oral cavity, tongue, lip, pharynx (throat), and larynx (voice box). Recommendations in the guideline may also apply to cancers of the salivary glands, nasal and paranasal sinuses, and nasopharynx. But it does not address cancers of the brain, thyroid, or esophagus because they are very different in terms of symptoms and treatment. RESOURCES: Head and Neck Cancer Survivorship Care GuidelineHead and Neck Cancer Survivorship Guideline Patient PageNutrition and physical activity guidelines for cancer survivorsSurvivorship care plansOnline co...Tue, 22 Mar 2016 23:00:00 +0100
In conclusion, the HPV16/18/31/33/45 mRNA test is not optimal for ASC‐US triage due to its low sensitivity and the substantial risk for precancer following a negative test. This article is protected by copyright. All rights reserved. (Source: International Journal of Cancer)Tue, 22 Mar 2016 06:00:00 +0100
(NaturalNews) One highly controversial Human Papillomavirus (HPV) vaccine, Gardasil, which is administered to young girls ostensibly to defend against an early onset of the only form of contagious cancer, has actually been responsible for more than 30 deaths, according to the site... (Source: NaturalNews.com)MedWorm Sponsor Message: Directory of the best January Sales in the UK. Find the best Christmas presents too.
Mon, 21 Mar 2016 23:00:00 +0100
Conclusions HPV16 antibodies were significantly more common in OPC versus non-OPC cases, particularly HPV16 E6 antibodies. (Source: Cancer Epidemiology)Mon, 21 Mar 2016 23:00:00 +0100
ConclusionAmong patients with CUP, p16‐positive status is an independent predictor of DFS but not overall survival (OS). © 2016 Wiley Periodicals, Inc. Head Neck, 2016 (Source: Head and Neck)Mon, 21 Mar 2016 23:00:00 +0100
ConclusionThe majority of HPV‐positive oropharyngeal SCCs have either integrated or both episomal and integrated HPV with no significant differences in survival among the groups. © 2016 Wiley Periodicals, Inc. Head Neck, 2016 (Source: Head and Neck)Mon, 21 Mar 2016 10:54:03 +0100
Authors: Knecht R, Bussmann L, Möckelmann N, Lörincz BB Abstract Treatment of patients with oropharyngeal squamous cell carcinoma (OPSCC) requires interdisciplinary collaboration. Besides oncologic control, organ and function preservation are important priorities. One treatment option is primary concomitant chemoradiotherapy (CRT), particularly for locally advanced head and neck cancer. Another option is sequential CRT, where induction chemotherapy may be followed either by radiation alone or by CRT. An important aspect of these modalities is the development of functional sequelae with regards to swallowing as a direct consequence of radiogenic fibrosis, as well as tissue ctoxicity associated with cisplatin-based chemotherapy. Conventional open surgical approaches are being incr...Mon, 21 Mar 2016 05:47:03 +0100
This study determined how the immortalization capacity of ten hrHPV types relates to DNA damage induction and overall genomic instability in HFKs.Twenty five cell cultures obtained by transduction of ten hrHPV types (i.e. HPV16/18/31/33/35/45/51/59/66/70 E6E7) in two or three HFK donors each were studied.All hrHPV-transduced HFKs showed an increased number of double strand DNA breaks compared to controls, without exhibiting significant differences between types. However, immortal descendants of HPV-transduced HFKs that underwent a prior crisis period (HPV45/51/59/66/70-transduced HFKs) showed significantly more chromosomal aberrations compared to those without crisis (HPV16/18/31/33/35-transduced HFKs). Notably, the hTERT locus at 5p was exclusively gained in cells with a history of crisis...MedWorm Sponsor Message: Directory of the best January Sales in the UK. Find the best Christmas presents too.
Mon, 21 Mar 2016 00:00:00 +0100
Conclusions These findings demonstrate distinct genomic differences between HPV-positive and HPV-negative OACs indicating different biological mechanisms of tumour formation. (Source: Journal of Medical Genetics)Mon, 21 Mar 2016 00:00:00 +0100
(Source: International Journal of Cancer)Mon, 21 Mar 2016 00:00:00 +0100
Human papillomavirus (HPV) type 16 (HPV 16) plays an etiologic role in the majority of cases of squamous cell carcinoma of the oropharynx (SCCOP), particularly those occurring in middle-aged patients and patients with no smoking history [1–6]. Chaturvedi et al., in an analysis of US incidence trends for oral cavity and oropharynx cancers stratified by age, demonstrated that the incidence of squamous cell carcinoma of the oral cavity (SCCOC) decreased overall but increased significantly among adults younger than 40years, consistent with an increasing incidence of SCCOP across age groups [6]. (Source: Oral Oncology)Mon, 21 Mar 2016 00:00:00 +0100
Abstract Recurrent respiratory papillomatosis (RRP) is a rare benign neoplasm of the respiratory tract caused by human papillomavirus types 6 and 11. Surgical removal of the papilloma by microdebridement or laser is the current standard of care, but in most cases the disease recurs and patients require repeated surgical intervention. Over time, repeated procedures can lead to complications such as significant vocal cord scarring and laryngeal stenosis. There is therefore an urgent need for adjuvant treatments or alternative therapies that can control the disease or prevent recurrence, but unfortunately there is currently no known universally effective adjuvant therapy. Challenges for evaluating the effectiveness of adjuvant treatment in RRP include variable success rates in patien...Sun, 20 Mar 2016 00:00:00 +0100
This article is protected by copyright. All rights reserved. (Source: British Journal of Dermatology)MedWorm Sponsor Message: Directory of the best January Sales in the UK. Find the best Christmas presents too.
Sat, 19 Mar 2016 23:00:00 +0100
This article is protected by copyright. All rights reserved. PMID: 26997147 [PubMed - as supplied by publisher] (Source: The British Journal of Dermatology)Sat, 19 Mar 2016 17:51:03 +0100
Authors: Yang L, Wang H, Wang Y, He Z, Chen H, Liang S, He S, Wu S, Song L, Chen Y Abstract In human cancer, molecular markers combined with clinical characteristics are used increasingly to predict prognosis. Prostate tumor overexpressed-1 (PTOV1), first identified in prostate cancer, is a key factor in tumor progression and correlates with unfavorable clinical outcomes. HPV infection status was tested by HPV E6-targeted multiplex real-time PCR and p16 immunohistochemistry (IHC). Real-time PCR and western blotting analyses were used to examine the mRNA and protein expression levels of PTOV1 in eight paired LSCC samples. IHC was performed to assess PTOV1 protein expression in 196 paraffin-embedded, archived LSCC samples. PTOV1 protein and mRNA expression was increased in LSCC tissu...Sat, 19 Mar 2016 17:44:02 +0100
CONCLUSIONS: Changing from cytology to hpv dna testing as the primary screening test for cervical cancer would be an acceptable strategy in Canada with respect to incidence, mortality, screening and diagnostic test volumes. PMID: 26985148 [PubMed] (Source: Current Oncology)Sat, 19 Mar 2016 00:00:00 +0100
The seminal observations linking inflammation and cancers dated back to mid nineteenth century when Virchow noticed that tumors tended to occur at sites of chronic inflammation. The hypothesis of a connection between inflammation and cancer was subsequently challenged by data demonstrating that acute inflammation contributed to cancer regression, even if epidemiologic studies supported that chronic inflammatory diseases are frequently associated with increased risk of cancers [1]. Nowadays, it has been realized that the development of cancers from inflammation might be a process driven by inflammatory cells as well as a variety of mediators, including cytokines, chemokines and enzymes, which altogether establish an inflammatory microenvironment [1]. (Source: Cytokine and Growth Factor Revi...Sat, 19 Mar 2016 00:00:00 +0100
(Source: The Journal of Dermatology)MedWorm Sponsor Message: Directory of the best January Sales in the UK. Find the best Christmas presents too.
Sat, 19 Mar 2016 00:00:00 +0100
ConclusionsLow‐grade AIN lesions can be caused by high‐risk HPV genotypes and vice versa. We therefore recommend for HIV‐positive MSM routine follow‐up and treatment of all dysplastic intra‐anal warts.This article is protected by copyright. All rights reserved. (Source: British Journal of Dermatology)Sat, 19 Mar 2016 00:00:00 +0100
This study assesses the impact that it has had on the rates of HPV uptake. (Source: American Journal of Obstetrics and Gynecology)Sat, 19 Mar 2016 00:00:00 +0100
Head and neck cancer (HNC) currently affects approximately 11 200 people in the UK, with an increasing proportion known to be caused by the human papillomavirus (HPV). We undertook a systematic review of studies measuring the psychosocial impact of HPV-related HNC and also studies measuring knowledge about the link between HPV and HNC among different populations. Searches were conducted on MEDLINE, Embase, PsycINFO, CINAHL Plus and Web of Science, with reference and forward citation searches also carried out on included studies. (Source: Clinical Oncology)Sat, 19 Mar 2016 00:00:00 +0100
CONCLUSIONS: Low-grade AIN lesions can be caused by high-risk HPV genotypes and vice versa. We therefore recommend for HIV-positive MSM routine follow-up and treatment of all dysplastic intra-anal warts. This article is protected by copyright. All rights reserved. PMID: 26994411 [PubMed - as supplied by publisher] (Source: The British Journal of Dermatology)Fri, 18 Mar 2016 23:00:00 +0100
Authors: Martín JM, Escandell I, Ayala D, Jordá E PMID: 27006016 [PubMed - as supplied by publisher] (Source: Actas Dermo-Sifiliograficas)MedWorm Sponsor Message: Directory of the best January Sales in the UK. Find the best Christmas presents too.
Fri, 18 Mar 2016 20:38:02 +0100
This article describes a case of FEH in a 57-year-old Brazilian patient presenting since childhood, with multiple lesions in the lips, buccal mucosa and tongue. The solitary tongue lesion underwent excisional biopsy and the histopathological analysis showed parakeratosis, acanthosis, rete pegs with a club-shaped appearance, koilocytosis and the presence of mitosoid cells. These microscopic findings in conjunction with clinical presentation were sufficient to establish the accurate diagnosis of FEH. Polymerase chain reaction (PCR) was performed, but no one human papillomavirus (HPV) subtype could be identified. Clinicians must be aware of this rare oral disease, which can even affect elderly patients, as we described here. Treatment may be indicated in selected cases due to esthetic and/or ...Fri, 18 Mar 2016 17:23:01 +0100
CONCLUSIONS: Offering HPV self-collection has the potential to considerably improve outcomes for unscreened and underscreened women. Nevertheless, these findings underscore the need for concerted strategies to encourage these women to join the mainstream HPV screening program. PMID: 26985849 [PubMed - as supplied by publisher] (Source: Med J Aust)Fri, 18 Mar 2016 00:00:00 +0100
Conclusion HPV-positive OPSCCs with a low count of CD3+ TILs or high expression of SERPINB1 have a worse OS, comparable with HPV-negative OPSCCs. This suggests that the immune system plays an important role in the carcinogenesis of the virally induced oropharynx tumors. (Source: Cancer Immunology, Immunotherapy)Fri, 18 Mar 2016 00:00:00 +0100
This article discusses the etiology and clinical presentation of HPV‐positive and HPV‐negative oropharyngeal cancer, noting distinctions between the 2 types. Recommendations for screening and prevention are provided. (Source: Journal of Midwifery and Women's Health)Thu, 17 Mar 2016 17:22:02 +0100
CONCLUSION: The purpose of the study was to explore the role of CMV in the development of MEC, as it might help to exploit this etiological agent as a therapeutic target. Similar to human papillomavirus (HPV), these might identify a subset of neoplasms with a varied biological behavior and alternative therapies. However, this vision is obscured by contradicting evidence in the literature. As of today, surgery remains the only best possible management for these patients unless proven otherwise. PMID: 26980959 [PubMed] (Source: Journal of Oral and Maxillofacial Pathology)MedWorm Sponsor Message: Directory of the best January Sales in the UK. Find the best Christmas presents too.
Thu, 17 Mar 2016 13:07:16 +0100
ConclusionsIn women with the studied well‐defined clinical indications for HPV testing, cobas and HC2 performed similarly in terms of the detection of HPV and ≥CIN2. (Source: Cytopathology)Thu, 17 Mar 2016 11:50:01 +0100
CONCLUSIONS: Primary HPV screening with genotyping represents a sensible combination of clinical effectiveness and costs, while reducing the risks associated with patient noncompliance. PMID: 26978241 [PubMed - in process] (Source: The American Journal of Managed Care)Thu, 17 Mar 2016 00:00:00 +0100
High-risk oncogenic human papillomavirus (HR-HPV) infection is the major cause for the development of cervical cancer and cervical intraepithelial neoplasia (CIN) [1]. Cervical cancer is the second most common cancer among women worldwide whereas in France, 3000 new cases of cervical cancer are detected each year, leading to 1102 deaths per year [2]. In France, cytological screening is not organized systematically at the country-wide level and it is recommended every 3 years in 25–65 years old women following 2 normal cytological exams. (Source: Journal of Clinical Virology)Thu, 17 Mar 2016 00:00:00 +0100
It is increasingly important to identify the presence of human papillomavirus (HPV) in patients with oropharyngeal squamous cell carcinoma, because HPV status is now useful for clinical trial stratification, prognostic determination, diagnosis in patients with neck masses, and identification of the primary tumor site. Therefore, it is important that the technique used for identification be feasible, accurate, reproducible, and cost effective. The authors summarize these aspects of HPV detection and the use of newer digital polymerase chain reaction technology for this purpose. See also pages. (Source: Cancer)Thu, 17 Mar 2016 00:00:00 +0100
CONCLUSIONSThe ddPCR of HPV E6/E7 is a novel and highly specific method of detecting HPV‐16 in OPSCC. Cancer 2016. © 2016 American Cancer Society. (Source: Cancer)MedWorm Sponsor Message: Directory of the best January Sales in the UK. Find the best Christmas presents too.
Thu, 17 Mar 2016 00:00:00 +0100
This article is protected by copyright. All rights reserved. (Source: International Journal of Cancer)Thu, 17 Mar 2016 00:00:00 +0100
In conclusion, our study supports the feasibility of urine surveys to monitor HPV vaccination and quantifies the effectiveness of the quadrivalent vaccine in women vaccinated after pre‐adolescence. Future similar surveys should detect increases in vaccine effectiveness if vaccination of 12 year‐olds continues. This article is protected by copyright. All rights reserved. (Source: International Journal of Cancer)Thu, 17 Mar 2016 00:00:00 +0100
Most women in developing countries have never attended cervical screening programmes and often little information exists on type-specific human papillomavirus (HPV) prevalence among these populations. Self-sam... (Source: Infectious Agents and Cancer)Thu, 17 Mar 2016 00:00:00 +0100
CONCLUSIONS: Our findings suggest the possible mechanism by which HPVE6 potentially regulate and maintain stem-like cancer cells through Hes1. PMID: 26988248 [PubMed - as supplied by publisher] (Source: Clinical Cancer Research)Thu, 17 Mar 2016 00:00:00 +0100
Authors: Bryan JT, Buckland B, Hammond J, Jansen KU Abstract In 2006, the first human papillomavirus (HPV) virus-like particle (VLP) vaccine was licensed. Gardasil(®), the quadrivalent HPV 6, 11, 16 and 18 recombinant VLP vaccine (4vHPV), developed by Merck demonstrated remarkable efficacy in prevention of important clinical pre-cursors to cervical cancer and genital warts. The vaccine was designed to protect against HPV 16 and 18 that cause ∼70% of cervical cancers and HPV 6 and 11 that cause ∼90% of genital warts. Initially, Gardasil(®) was indicated in the United States for women 9-26 years of age for the prevention of HPV 16 and 18-related cervical, vulvar and vaginal cancer, HPV 6, 11, 16 and 18-related genital intraepithelial neoplasia and the prevention of HPV 6 and 11...MedWorm Sponsor Message: Directory of the best January Sales in the UK. Find the best Christmas presents too.
Wed, 16 Mar 2016 00:34:36 +0100
Large cell neuroendocrine carcinoma (LCNEC) is a high-grade neuroendocrine neoplasm first described in the lung and subsequently well documented in many other anatomic sites. It has only recently been recognized that LCNEC can also occasionally arise in the head and neck. The role of human papillomavirus (HPV), which is associated with some small cell carcinomas of the head and neck, has not been investigated for LCNEC. We sought to further characterize the histologic, immunophenotypic, and clinical features of LCNEC and also investigate the role of HPV in this newly described group of tumors. The surgical pathology archives of 2 large academic institutions were searched for cases of LCNEC arising in the head and neck. p16 immunohistochemistry and HPV in situ hybridization were performed, ...Wed, 16 Mar 2016 00:34:36 +0100
Lower female genital tract tumors with adenoid cystic differentiation are rare, and data on their relationship with high-risk human papillomavirus (HPV) are limited. Here we report the clinicopathologic features from a case series. Tumors with adenoid cystic differentiation, either pure or as part of a carcinoma with mixed differentiation, arising in the lower female genital tract were evaluated by means of immunohistochemical analysis for p16 expression and in situ hybridization using 1 or more probes for high-risk HPV (a high-risk probe covering multiple types, a wide-spectrum probe, and separate type-specific probes for HPV16 and HPV18) and when possible by polymerase chain reaction for high-risk HPV. Six cervical carcinomas with adenoid cystic differentiation admixed with various combi...Wed, 16 Mar 2016 00:00:00 +0100
(Source: Perspectives on Sexual and Reproductive Health)Tue, 15 Mar 2016 20:02:03 +0100
The human papillomavirus vaccine was first recommended for adolescent girls in the United States in 2006. Since that time, the prevalence of the cancer-causing virus has been dropping among young women, according to a new study. (Source: CNN.com - Health)Tue, 15 Mar 2016 18:36:31 +0100
By most measures, the United States' business-friendly environment has proven to be fertile for medical innovation. Compared to other countries, America has filed the most patents in the life sciences, is conducting most of the world's clinical trials and has published the most biomedical research. That's what makes the medical prominence of Cuba all the more surprising to those who view a free market as an essential driver of scientific discovery. Cuba is very poor, and yet the country has some of the healthiest, most long-lived residents in the world -- as well as a medical invention or two that could run circles around U.S. therapies, thanks to government investment in scientific research and a preventive public health approach that views medical care as a birthright. The isla...MedWorm Sponsor Message: Directory of the best January Sales in the UK. Find the best Christmas presents too.
Tue, 15 Mar 2016 00:00:00 +0100
ABSTRACT Warts are common epidermal growths caused by human papillomavirus that often cause significant discomfort and embarrassment. Current treatment options include topical therapies, cryotherapy, laser vaporization, and surgical excision. Many of these options are destructive and may result in scarring, while less aggressive approaches can lead to lesion recurrence. Additionally, these local modalities are not practical for patients with a large number of warts. Systemic approaches such as immunotherapy have demonstrated success in treating multiple lesions by combining a targeted approach with upregulation of the host immune system. An extensive literature review was performed to evaluate the various vaccine antigens that have been used intralesionally to treat cutaneous and anogenita...Tue, 15 Mar 2016 00:00:00 +0100
Publication date: Available online 14 March 2016 Source:Pathology - Research and Practice Author(s): Marián Švajdler, Jana Kašpírková, Ladislav Hadravský, Jan Laco, Pavol Dubinský, Ľubomír Straka, Ondrej Ondič, Michal Michal, Alena Skálová Most cases of cystic squamous cell carcinoma (SCC) metastases in the upper neck are associated with an oropharyngeal primary, namely human papillomavirus (HPV)-associated SCC arising in the palatine or lingual tonsil. A retrospective study was performed on 22 patients who presented with cystic head and neck SCC metastases. The purpose of the study was to find out whether histological characteristics, p16 protein expression, HPV and Epstein-Barr virus (EBV) status could be useful in predicting the localization of the primary tumor. ...Tue, 15 Mar 2016 00:00:00 +0100
Persistent human papillomavirus (HPV) infection is established as a necessary cause for cervical, anogenital and oropharyngeal cancers [1,2]. Most genital HPV infections are transient and clear within 6–12 months [3]. Therefore, HPV DNA testing cannot measure cumulative HPV exposure. The antibody responses to the HPV capsid are known to be stable over time, providing a useful measure of cumulative HPV exposure [4]. (Source: Journal of Clinical Virology)Tue, 15 Mar 2016 00:00:00 +0100
Abstract In the dose-escalation phase of a Phase I clinical trial in which six subjects each were vaccinated with PepCan at the 50, 100, 250, and 500 μg per peptide dose, the 50 μg dose showed the best histological regression rate. Ten additional subjects were vaccinated at this dose in the final dose phase. As with the dose-escalation phase, no dose-limiting toxicities were observed. Overall, the histological regression rates were 50 % at the 50 μg dose (7 of 14) and 100 μg dose (3 of 6), and 45 % overall (14 of 31). Of subjects in whom HPV type 16 (HPV 16) was detected at entry, it became undetectable in three subjects after vaccination, and the viral loads significantly decreased in nine subjects in whom HPV 16 infection was detected at entry and exit (p = 0.008). I...Tue, 15 Mar 2016 00:00:00 +0100
A secific mechanism explaining the higher chemoradiation responsiveness of human papillomavirus (HPV)-positive head and neck squamous cell carcinoma (HNSCC) and the modulation of this effect by tobacco exposure remains unidentified. Promoter hypermethylation (HM) of the DNA-repair O6-Methylguanine (O6-MG)-DNA-methyl-transferase (MGMT) gene is an independent predictor of response to chemoradiation and survival in gliomas and lymphomas. We are investigating the role of MGMT in HNSCC in the context of tobacco exposure and HPV status. (Source: International Journal of Radiation Oncology * Biology * Physics)MedWorm Sponsor Message: Directory of the best January Sales in the UK. Find the best Christmas presents too.
Tue, 15 Mar 2016 00:00:00 +0100
Authors: Santos EU, Lima GD, Oliveira ML, Heráclio SA, Silva HD, Crovella S, Maia MM, Souza/ PR Abstract Polymorphisms in chemokine receptors play an important role in the progression of cervical intraepithelial neoplasia (CIN) to cervical cancer (CC). Our study examined the association of CCR2-64I (rs1799864) and CCR5-Δ32 (rs333) polymorphisms with susceptibility to develop cervical lesion (CIN and CC) in a Brazilian population. The genotyping of 139 women with cervical lesions and 151 women without cervical lesions for the CCR2-64I and CCR5-Δ32 polymorphisms were performed using polymerase chain reaction-restriction fragment length polymorphism. The individuals carrying heterozygous or homozygous genotypes (GA+AA) for CCR2-64I polymorphisms seem to be at lower risk for cervica...Tue, 15 Mar 2016 00:00:00 +0100
Authors: Stratton KL, Culkin DJ Abstract Human papillomavirus (HPV) is a widespread sexually transmitted infection. In both men and women, HPV infection can result in a spectrum of genitourinary manifestations ranging from genital warts to cancer. Cervical cancer is nearly always associated with high-risk HPV infection. For men, penile cancer can develop following or independently of HPV infection. Basaloid and warty subtypes of penile squamous cell carcinoma are most frequently associated with HPV infection. Further research into the molecular alterations caused by HPV infection may provide prognostic markers and future treatment targets. Until an effective treatment for HPV infection is developed, prevention will remain the focus of disease control. For women, vaccination is incr...Mon, 14 Mar 2016 15:00:00 +0100
Full or partial vaccination with the quadrivalent human papillomavirus vaccine reduced the overall risk of abnormal cervical pathology by 36%, based on data from a retrospective cohort study of just... (Source: Pediatric News)Mon, 14 Mar 2016 00:00:00 +0100
In this study, we designed and validated a new method based on multiplex PCR-deep sequencing of the E6/E7 region of HR-HPV types to characterize HPV intra-type variants in clinical specimens. Validation experiments demonstrated that this method allowed reliable identification of the different lineages of oncogenic HPV types. Advantages of this method over other published methods were represented by its ability to detect variants of all HR-HPV types in a single reaction, to detect variants of HR-HPV types in clinical specimens with multiple infections, and, being based on sequencing of the full E6/E7 region, to detect amino acid changes in these oncogenes potentially associated with increased transforming activity. (Source: Viruses)MedWorm Sponsor Message: Directory of the best January Sales in the UK. Find the best Christmas presents too.
Mon, 14 Mar 2016 00:00:00 +0100
ConclusionsOur study provides the first evidence that TLR2 gene polymorphisms are associated with high‐risk type HPV‐related cervical neoplasia and may play an important role in susceptibility to HPV infection. Further large‐scale and functional studies are needed to confirm the role of TLR2 gene polymorphisms in HPV‐related cervical neoplasia.This article is protected by copyright. All rights reserved. (Source: Acta Obstetricia et Gynecologica Scandinavica)Mon, 14 Mar 2016 00:00:00 +0100
This cohort study examines the effect of human papillomavirus vaccination on the subsequent risk for abnormal cervical cytology results among urban, low-income minority females. (Source: JAMA Pediatrics)Mon, 14 Mar 2016 00:00:00 +0100
The management of oropharyngeal carcinoma represents an increasing clinical challenge, because of its rising incidence, particularly in younger patients as a result of human papillomavirus (HPV) infection, and because significant technological advances have occurred in radiotherapy and surgery over the last 10 years that have increased treatment options for patients, with little robust evidence yet of their relative merits. As a result, there is a lack of clinical consensus on the optimum treatment modality, reflected in wide variation in practice between different cancer networks across the UK. (Source: Clinical Oncology)Mon, 14 Mar 2016 00:00:00 +0100
Although systematic reviews (SR) report that human papillomavirus (HPV) increases the risk of breast cancer, there are still disputes regarding this association. In particular, it has been argued that the risk... (Source: Infectious Agents and Cancer)Sun, 13 Mar 2016 23:00:00 +0100
Authors: Švajdler M, Kašpírková J, Hadravský L, Laco J, Dubinský P, Straka Ľ, Ondič O, Michal M, Skálová A Abstract Most cases of cystic squamous cell carcinoma (SCC) metastases in the upper neck are associated with an oropharyngeal primary, namely human papillomavirus (HPV)-associated SCC arising in the palatine or lingual tonsil. A retrospective study was performed on 22 patients who presented with cystic head and neck SCC metastases. The purpose of the study was to find out whether histological characteristics, p16 protein expression, HPV and Epstein-Barr virus (EBV) status could be useful in predicting the localization of the primary tumor. The primary site was identified in 20 of 22 patients and included the oropharynx in 14 patients (63.6%), the nasopharynx in 3 pat...MedWorm Sponsor Message: Directory of the best January Sales in the UK. Find the best Christmas presents too.
Sun, 13 Mar 2016 19:07:07 +0100
Conclusions: Racial differences in immune markers of HPV exposure and the epidemiology of HPV-related cancers may be linked to differences in patterns of sexual behaviors. (Source: Sexually Transmitted Diseases)Sun, 13 Mar 2016 19:07:07 +0100
Conclusions: We found a significantly decreasing incidence of GWs in women up to 35 years of age after the start of the human papillomavirus vaccination program. A similar pattern was observed for men aged 12 to 29 years, indicating substantial herd protection. (Source: Sexually Transmitted Diseases)Sun, 13 Mar 2016 19:07:07 +0100
Conclusions: Anal HR-HPV infection is high for young Nigerian MSM, and rates are amplified in those coinfected with HIV. Providing universal coverage as well as catch-up immunization for young MSM may be an effective anal cancer prevention strategy in Nigeria. (Source: Sexually Transmitted Diseases)Sat, 12 Mar 2016 00:00:00 +0100
Conclusion For over-screened women, the harms associated with a lower test specificity outweigh the life years gained when switching from primary cytology to primary HPV testing. The extent of over-screening should be considered when deciding on inclusion of primary HPV screening in cervical cancer screening guidelines. (Source: Cancer Causes and Control)Fri, 11 Mar 2016 11:29:03 +0100
CONCLUSION: Our case provides insight into the potential use of ingenol mebutate for EV patients unresponsive to traditional medical treatments.MedWorm Sponsor Message: Directory of the best January Sales in the UK. Find the best Christmas presents too.
Fri, 11 Mar 2016 00:00:00 +0100
In the United States, approximately 40–80% of oropharynx squamous cell cancers (OPSCC) are caused by human papillomavirus (HPV) [1]. While the overall incidence of head and neck SCC in the United States is declining, the rate of HPV-associated OPSCC appears to be rising [2]. In fact, the Centers for Disease Control and Prevention (CDC) found that OPSCC were one of only five cancers increasing in incidence from 1975 to 2009 [3]. Clinically, HPV-positive cancers typically arise in the lingual and palatine tonsils, are poorly differentiated, have lower tumor (T) stage with more advanced nodal (N) stage and affect younger, white males [4]. (Source: Oral Oncology)Fri, 11 Mar 2016 00:00:00 +0100
Abstract Infection with low-risk human papillomaviruses (HPVs), mostly type 6 and 11, in the upper respiratory tract causes recurrent respiratory papillomatosis (RRP). Despite a relatively low incidence rate, RRP imposes significant morbidity upon affected patients and an enormous financial burden on the healthcare system. RRP can be further categorized into juvenile-onset RRP and adult-onset RRP, depending on the onset age. They may associate with different risk factors and incidence rates. Here, we review the epidemiology of RRP caused by low-risk HPV infection and discuss the impact of HPV vaccination on the prevalence of low-risk HPVs that cause RRP. (Source: Current Otorhinolaryngology Reports)Fri, 11 Mar 2016 00:00:00 +0100
Conclusions Cases from Guatemala, which were mostly nonkeratinizing SCC and originated from the crypt/reticular epithelium of the tonsil, had high-risk integrated HPV, whereas in Brazilian cases, which were mostly keratinizing SCC that originated from the surface epithelium, there was no association with HPV. (Source: Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology)Fri, 11 Mar 2016 00:00:00 +0100
Conclusions Earlier studies have depicted associations between TV and HPV with possible enhancement of HPV virulence due to TV. Lack of awareness and hygiene, and limited access to gynecologists in LMICs lead to frequent and persistent RTIs which aid and abet HPV infection and CC occurrence. These also need to be addressed to reduce CC and RTIs among women in LMICs. (Source: The Journal of Obstetrics and Gynecology of India)Fri, 11 Mar 2016 00:00:00 +0100
Authors: Karaki S, Pere H, Badoual C, Tartour E Abstract A pool of long synthetic peptides derived from HPV16 proteins induce objective partial or complete histological regression of lesions in more than 50% of patients with high-grade vulvar (VuVIN3) and vaginal intraepithelial neoplasia (VaIN3). The intensity of T cell response induced by the vaccine was correlated with clinical response. PMID: 26968203 [PubMed - as supplied by publisher] (Source: Clinical Cancer Research)MedWorm Sponsor Message: Directory of the best January Sales in the UK. Find the best Christmas presents too.
Thu, 10 Mar 2016 16:16:02 +0100
Authors: Kwon T, Moon KH, Yang SH, Roh MC, Lee SH, Kim JW, Kim IK, Roh KH, Park S Abstract Further understanding of male human papillomavirus (HPV) infection is necessary to prevent infection in men, as well as transmission to women. In our current study, we investigated patterns of HPV infection and genotype distributions in male genital warts using the Anyplex II HPV28 Detection kit. We reviewed the medical records of 80 male patients who presented to 5 neighborhood clinics in Ulsan, Korea, for the treatment of genital warts between April 2014 and January 2015. All patients underwent HPV genotyping. The prevalence and characteristics of HPV infection were analyzed, and the patterns of HPV infection according to age were assessed. Among the study patients, 13 (16.3%) were negative...Thu, 10 Mar 2016 00:00:00 +0100
Conclusions To the best of our knowledge, this is the first population-based study of AGW incidence and HSU in Ontario. The sex and age distribution of individuals with incident and prevalent AGWs in Ontario was similar to that of other provinces before HPV vaccine programme implementation in Canada. (Source: BMJ Open)Thu, 10 Mar 2016 00:00:00 +0100
Porocarcinoma is a malignant epithelial tumour originating from or differentiating toward the intraepidermal eccrine duct (i.e. acrosyringium). Although considered the most frequent sweat gland carcinoma, the tumour is relatively rare, representing 0,005–0,01% of epithelial cutaneous neoplasms [1]. However, it is possible that the real incidence is underestimated, because of the difficult clinicopathologic distinction from the more acquainted squamous cell carcinoma [2,3]. About 20% of porocarcinomas can recur and metastasize to regional lymph nodes and rarely to distant organs; mortality rate has been estimated as high as 67% of patients with nodal metastases [4]. (Source: Journal of Clinical Virology)Thu, 10 Mar 2016 00:00:00 +0100
CONCLUSION: This study provides greater knowledge of dermatological diseases in prison and shows teledermatology to be a tool suited to the specific constraints of this universe, while providing inmates with medical care as close as possible to that of the general population, and it thus helps ensure that their fundamental human rights are upheld. PMID: 26971370 [PubMed - as supplied by publisher] (Source: Annales de Dermatologie et de Cenereologie)Thu, 10 Mar 2016 00:00:00 +0100
Earlier this month we reported on the big drop in rates of human papillomavirus (HPV) infection in the United States. A study in the journal Pediatrics shows that since the introduction of the HPV vaccine six years ago, the rate of HPV infection has dropped 64 percent for girls ages 14 to 19. The Centers for [...] (Source: News from Mayo Clinic)MedWorm Sponsor Message: Directory of the best January Sales in the UK. Find the best Christmas presents too.


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Peter Marshman, Program author
The Youth Opportunities' Personal Leadership Program (PLP) was originally developed for businesses, as a management tool to increase employees' motivation for their work, both individually and as a team. With many employees reaching beyond their perceived capabilities and job responsibilities, Program author Peter Marshman OAM soon realised the benefit it could have on school aged participants. In 1997, Peter founded the charity Youth Opportunities Association (SA) Inc with the aim of developing the leadership skills of young people so they would be able to help themselves and make positive life choices, breaking the cycle of long term unemployment and disadvantage.
The first school based PLP was delivered in 1998 to Year 10 students in two low socio-economic schools in Adelaide's North, Salisbury and Smithfield Plains High Schools. The positive outcomes instigated further development and expansion across metropolitan and regional South Australia. 18 years on the PLP has been delivered in over 40 schools and organisations in metropolitan and regional South Australia changing the lives of over 10,000 young people.
Youth Opportunities are proud to help around 600 young people across South Australia each year.


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Love "Paranoid" to bits.
Love "Paranoid" to bits.
At this point, I feel sorry for the haters, they're really going to miss out on one hell of a performance. The Chems will set the bar, we'll see where Arcade Fire and Kanye take it from there.
I'm also fairly confident the Kanye will be there all weekend, I think Hova and B told him that's the way to do it. He should be pretty inspired by Sunday evening.
I keep saying, "Mr. West is in the buildin'." That's not gonna work on the polo fields...
Kayne is definitly going to put on one hell of a show. People dont like his attitude and self righteous, sure I get it. Why miss one of the best sets of the weekend though. Its going to be on a massive level and you know he is going to bring it. Is he my favorite hip hop artist? Far from it, but I couldnt imagine missing his set this weekend. Anyone who is thinking about it should reconsider. Come next week this time we are going to be looking at a poll for "best set" and Kayne is going to have more than a few votes on it I can guaranty that.
I found this weird youtube, possible spoilers:
e: to be less vague, I was searching "coachella" and found this video. it's called "kanye casting coachella" and appears to be a rehearsal, but there's no info on it other than the title. it doesn't really give too much away, especially if you saw Runaway.
Last edited by Trick Loves The Kids; 04-13-2011 at 12:50 PM.
Ahhhhh must resist
-Kanye West
Someone please count the number of times he says (I mean raps) "lights." I want to know all of the times.
3/18-19: Starry Nites Festival @ Live Oak
3/25: Peggy Gou, Aaron Clark, Mike Gushanksy @ Audio
3/27: Strand of Oaks @ The Independent
3/31: Max Cooper @ PW
3/31: Shifted @ f8
4/5: Tin Man @ f8
4/7: Cosmin TRG @f8
4/8: Anthony Naples, Solar @ Monarch
4/12: King Gizzard and the Lizard Wizard @ The Fillmore
Too much vanilla and not enough fucking mocha in that rehearsal vid!
Kanye got the best time slot by far. That show is gonna be dope. Hope the haters just stay far away from the stage.
Coachella should really limit the number of acts and increase the length of each set. 55 minutes for PJ Harvey? 45 for Saadiq? Gotta be kidding.
I really want 'Touch The Sky'. Song got me hooked and I haven't stopped.
Kanye returns 2015?
KANYE is horrible ya Bigot!
Yep plus a new album too
*keeping fingers crossed until January*
I too believe that'll he'll be on the line-up.
fuckin' with the lights on
I'm really hoping for this to happen, especially with all of the shitty names being thrown around for potential 2015 headliners.
Dude is devoting like three weeks right now to designing his Adidas sneakers . . .
Anything is possible...


text: 888 AWUS83 KARX 282029 RWSARX IAZ008>011-018-019-029-030-MNZ079-086>088-094>096- WIZ017-029-032>034-041>044-053>055-061-290330- Weather Summary for Upper Mississippi River Valley National Weather Service La Crosse WI 330 PM CDT Tue Mar 28 2017 Mostly sunny skies were seen across much of the region this afternoon. Temerature were mainly in the middle 50s to around 60 by mid afternoon. Clouds will increase tonight, especially after midnight ahead of low pressure moving into the southern and central Plains. Otherwise, look for lows tonight in the 30s. Rain moves back in for Wednesday through Thursday, with the bulk of this falling along and south of I-90. Most of this precipitation will fall as rain, but some snow will mix in Wednesday night. $$ Breeser


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Contrast Strapless Mini dress
Michelle Mason
- Self: 63% poly , 33% viscose , 4% elastane
Lining: 100% polyamide - Neckline to hem measures approx 25" in length
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- Revolve Style No. MASO-WD192
- Manufacturer Style No. M-9626
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- Size Guide
- Need size help? Contact our Style Expert!
Launched in 2002 as a diffusion from designer Michelle Mason's eponymous label, Mason is a youthful collection of playful garments inspired by modern shapes and classic attire. Her line offers sweetly draped and embellished blouses, tanks and tops in colors that range from muted greys to vibrant pinks. The Los Angeles-based designer has become a well known name among stylish red carpet regulars like Angelina Jolie, Cameron Diaz and Natalie Portman and fashion bibles like Elle and Vogue have listed several of the Mason's designs as wardrobe essentials.


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Photos: Rocko's Tacos is serving tacos, burritos and margs in Belmar
All photos by Philip Poston |
Rocko's Tacos and Margaritas, the latest outpost in the Little Pub Company's string of neighborhood pubs, opened late last month in the Belmar Shopping Center.
The restaurant serves up ten different types of meat on its burrito, taco and appetizer menus, and all of its tacos are made with organic corn and wheat tortillas. Open seven days a week, Rocko's Tacos includes its full menu until 1 a.m.
See also: - The answers to life's important questions can be found at Tacos y Salsas - Exclusive first look: Moontower Tacos opens in Capitol Hill - First look: Cool Ranch Doritos Tacos Locos launches in Denver
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- Model: IPH-1190-FRSTRQ
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What's Included
- Octane Case for Apple iPhone 6 and 6s
Product Features
For a precise fit.
Combines a Plextonium polycarbonate back shell and Flex2O TPU bumper for a reliable armor.
Meets the MIL-STD-810G drop test standard, surviving falls from up to 4'.
Provides a smooth textured exterior to prevent drops and slips.
Lets the design of your device show through.
Apple, the Apple logo and iTunes are trademarks of Apple Computer, Inc., registered in the U.S. and other countries. iPod is a trademark of Apple Computer, Inc.


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Meet the family at the core of Nina Raine's smartly wise, well-acted and subtle drama Tribes at the Barrow Street Theater: three grown kids and parents all living under the same roof.
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German Shepherd Breeder of Black and Red Puppies For Sale Von der Stadtrand German Shepherd Breeder Rich Red and Black Police Military World Class Quality…
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$400Princess is 4. She is awesome, obedient, fully house trained and comes with food and her crate. We are moving and can no longer keep her.


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The softness you've always dreamed of is now available in carpet. Introducing UltraTouch® Satin made of soft Anso® nylon – the softest UltraTouch brand carpet yet. UltraTouch Satin carpet delivers unheard-of softness, colors in harmony with nature, amazing warranties, and durability for the most active families.
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Wednesday, June 23, 2010
Disneyland, December 1956, Pt. 3
The rest of this series takes place in Frontierland. Hope you can stand a few days in the untamed parts of early Disneyland. It's December 1956, and although we have a Keelboat and Fowler's Harbor, there's still no Columbia, Haunted Mansion, Fantasmic, OR Critter Country!
A somewhat blurry shot taken from The Twain:
And here's the mighty Mark Twain in the flesh; it really is a little startling to see so few people, so little landscaping, and even a telephone pole or two!
It's Christmas time at the Horseshoe:
The closeup shows the Oaks Tavern, which is now the Stage Door Cafe:
Anybody want a souvenir crate from the dock?
A closeup shows the buildings along New Orleans Street, the precursor to New Orleans Square:
Follow my Daveland updates on Twitter. See more Frontierland photos at my regular website.
6 comments:
- Thufer said...
Take the telephone poles out of that first picture and the mind drifts back to a time and place way, way back. Good picture.
\From the early days department\ one of the things I wish I could have experienced; Oaks Tavern! Would loved to have sat right there and enjoyed that fare. - 5:28 AM
- Vintage Disneyland Tickets said...
Oh boy, I'mo lovin these!
What's with the second story on the Oaks Tavern, the walls for the balcony look unfinished or was the the "look"? By 1960 it would be smoothed out (link)
Awesome series Dave, I'm still soaking in yesterday post!!!! - 6:22 AM
- Major Pepperidge said...
I'm sure that at least half of my slides are of Frontierland... people just were fascinated by that land. Love that first picture, so barren and yet still cool.
- TokyoMagic! said...
VDT, I think that's Christmas garland over the doorways on the upper level of the Oaks Tavern.
More terrific photos, Dave. Not to be greedy, but I'm hoping there's a part 4 & 5! - 11:02 AM
- Connie Moreno said...
I am LOVING these!!! WOW!!!
- Alex Blasingame said...
I've never noticed antlers hanging from the structure at the Mark Twain dock. When did they remove them? Thanks for sharing the great pics.


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BOGgear® BOG - POD® Q - STIK Multi - purpose Monopod
Item # WX2-193248
- Details & Specs
BOGgear® BOG - POD® Q - STIK Multi - purpose Monopod. Shooting stick, walking stick, camera and binocular rest in 1!
Head out for adventure without dragging around a bunch of cumbersome gear... all you need is the Q-STIK Multi-purpose Monopod:- Removable Universal Shooting Rest&trade with quick-change 360° swivel stem
- Hikers grip provides comfortable hand support
- Rapid-adjust twist locks loosen or tighten leg sections with just a couple of turns
- Inch markers on middle leg sections help set height and also double as a measuring stick
- Removable rubber feet reveal carbide tip for better grip on ice and hard ground
- Includes compass top, camera adapter, binocular rest and carry bag
- Weighs just 15 ozs., overall length of 32", adjustable to 68", with Universal Shooting Rest installed.
- Reviews
- Frequently Asked Questions
- Articles & Tips


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Sunday, August 19
Showcase Snday (#16)
11 comments:
Oh awesome!! I think the postoffice have my copy of The Diviners getting it redelivery was too big for my letter box. Lol. I also got Clarity but I'll do that in a different haul!
Check out My Book HaulI love that cover of The Diviners and can't wait to see what you think of it! It looks amazing!(: Happy Reading! :D
Ivy Book BindingsAwesome haul this week! You always get such lovely books to read. I have already added a few of these to my TBR list.
Happy Reading,
My Sunday Edition @ Paulette's PapersDiviners sounds really good, they all do really. Enjoy :)
Katja @ YA's the WordI know you have started BD now and Im so nervous to see what you think of it!!!! Its seriously my fav read in a long time THat and Obsidian together make up my top spot book of forever!!!! I also have the Diviners got it at ALA and damn its so huge!!!! but looks really great!!! Great books this week lady!
Tara's Haul


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What does jawbone mean?
Definitions for jawboneˈdʒɔˌboʊn
Here are all the possible meanings and translations of the word jawbone.
Princeton's WordNet
lower jaw, mandible, mandibula, mandibular bone, submaxilla, lower jawbone, jawbone, jowl(verb)
the jaw in vertebrates that is hinged to open the mouth
shmooze, shmoose, schmooze, schmoose, jawbone(verb)
talk idly or casually and in a friendly way
The bone of the lower jaw, the mandible.
Any of the bones in lower or upper jaw.
To talk persistently to persuade a person or people to cooperate.
Origin: jaw + bone
Webster Dictionary
the bone of either jaw; a maxilla or a mandible
The Jawbone is a line of Bluetooth mobile phone headsets produced by Aliph Inc, a privately held San Francisco-based consumer technology company founded by Alexander Asseily and Hosain Rahman in 1999. Since the introduction of the line in December 2006, it has been widely regarded as one of the best Bluetooth headsets available. The current model in the line is the Jawbone Era, which, like other models, sports a skin contact microphone that comes in contact with the wearer's face and gives the line its name. A defining feature of the Jawbone line is the integration of Aliph's NoiseAssassin adaptive signal processing technology, which was originally developed for DARPA to reduce communication background noise in military environments.
For more than a decade, Jawbone has developed products and services for the mobile lifestyle unparalleled in their innovation, ease-of-use and sophistication of design. The company is the creator of the award-winning and best-selling premium ICON Bluetooth headset; the inventor of NoiseAssassin® technology, the world's first and only military-grade noise eliminating technology; JAMBOX, the first intelligent wireless speaker and speakerphone; as well as THOUGHTS, a free mobile service that allows users to utilize their voice in a new way. A 2010 IDSA Design of the Decade winner, Jawbone is committed to delivering innovative products that improve the mobile lifestyle through ever-changing software and wearability. Jawbone is privately-held and headquartered in San Francisco.
Chaldean Numerology
The numerical value of jawbone in Chaldean Numerology is: 9
Pythagorean Numerology
The numerical value of jawbone in Pythagorean Numerology is: 7
Sample Sentences & Example Usage
The Federal Reserve continued to jawbone the market with additional hawkish comments about the potential for an interest rate hike in December.
Images & Illustrations of jawbone
Translations for jawbone
From our Multilingual Translation Dictionary
- mandíbulaCatalan, Valencian
- Kiefer, KieferknochenGerman
- γνάθος, κάτω γνάθοςGreek
- mandíbulaSpanish
- [[leuan]] [[luu]], taivutella, alaleuanluu, ympäri, leukaluuFinnish
- peirceall, pìos ìosal a' ghuibScottish Gaelic
- állkapocscsontHungarian
- 턱뼈, 거흠Korean
- cêlefekKurdish
- rahang bawah, tulang pengancing, tulang bercagak, tulang rahang, mandibelMalay
- kaaksbeenDutch
- че́люстная кость, че́люстьRussian
- чељуст, čeljustSerbo-Croatian
- käkben, underkäksbenSwedish
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"jawbone." Definitions.net. STANDS4 LLC, 2017. Web. 28 Mar. 2017. <http://www.definitions.net/definition/jawbone>.


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There's not a whole lot out there. You can find some videos on YouTube, and here's some info at Strew-Mac: http://www.stewmac.com/freeinfo/Electronics/Pickup_building/i-1465.html There is also the Pickup Makers Forum, at the Electronic Music Forum. http://music-electronics-forum.com/forumdisplay.php?f=11 (seem to be down at the moment)
ok thats a start. thank you. i also found quite a bit of BEGINNER information at ehow.com does anyone here make their own pickups? i understand it's long and tedious to wind 3-10,000 wraps on the pickups, but that aside, what about construction? some tried, tested, and true methods? thanks for any help you guys can give
It's not that tedious. Takes about 10 minutes usually. You are not winding them by hand, but hand guiding the wire while spinning the bobbin on some sort of coil winding machine. This can be as simple as a power drill mounted on a stand.
thanks again. when i wrote the previous post my plan was to do it BY HAND, but since then i've seen enough simple designs using sewing machines, drills, etc... but what can you use to count your turns?


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Nothing can stop these dirty old men from finding dumb and desperate teens who will do anything for a little bit of dough. They teach these little teens what it's like to be with not just one, but two real men and they learn that a little bit of cash can go a long way on a hot teen looking for some shopping money. Watch the teen next door be turned into a nasty little whore.
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People are often impressed by those that are bilingual, trilingual or even have the ability to speak more than three languages -- so we definitely had to highlight the 60 Latino stars who are fluent in Spanish.
Keeping up with that trend, we now present to you 18 impressive non-Latino celebs who speak Spanish:
View All Slides:
Kourtney Kardashian
The oldest and tiniest Kardashian sister not only speaks Spanish, but she told People in 2011 that she was teaching son Mason the language as well. "We like to speak Spanish to him," she said.
Ben Affleck
The actor and his brother Casey are both fluent in Spanish thanks to the time they spent living in Mexico.
Maya Angelou
The famous author has traveled extensively throughout her lifetime, and thanks to her travels, she was able to master speaking Spanish.
David Beckham
The super sexy futbol star learned Spanish while playing for Real Madrid.
Monica Bellucci
The 48-year-old Italiana is fluent in Spanish and even appeared in 1998's A Los Que Aman.
Kate Bosworth
The Movie 43 California native speaks Spanish fluently.
Matt Damon
Damon is not only married to a Spanish-speaking Argentine beauty, he is also highly proficient in the language. The actor studied Spanish through an immersion program in Mexico and later put those skills to use as he backpacked through Mexico and Guatemala.
Danny DeVito
The 68-year-old Italian American proved his strength in Spanish when he voiced the Spanish and Latin American versions for his character in The Lorax.
Gwyneth Paltrow
Thanks to a summer spent abroad as a foreign exchange student in Spain, Paltrow learned to speak the language and is now completely fluent.
Matthew McConaughey
Camila Alves' husband picked up on the Spanish language while growing up in Uvalde, Texas.
Will Smith
He may not be fluent in the language, but Smith has been able to take on the challenge of doing interviews in Spanish rather successfully.
Dakota Fanning
The young actress utilized Spanish (and very well) for her role in the 2004 film Man on Fire where she was the daughter of Marc Anthony's character.
Natalie Portman
The 32-year-old star, who was born in Israel, holds some great conversational Spanish skills.
Viggo Mortensen
Mortensen is quite the linguist! He speaks three languages fluently, including Spanish, which he learned while living in Argentina with his family.
Will Ferrell
The hilarious actor took on a role in the Spanish-language 2012 movie Casa de Mi Padre which helped him learn to speak a language he did not know how to speak before signing on.
Jimmy Kimmel
We were impressed by Kimmel when he conducted an interview with Will Ferrell in March 2012 fully in Spanish.
Kobe Bryant
The Los Angeles Lakers player, who is married to Latina Vanessa Bryant, is fluent in Spanish. He learned the language while traveling with his father as a young child.
Jada Pinkett Smith
Like her husband, Will Smith, the 41-year-old beauty speaks pretty good Spanish and has even done interviews fully in Spanish with Latino media outlets.