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Travel News
Here we share all sorts of China travel news. We offer news on sites, Chinese culture, Chinese history, restaurants, and so much more. We hope that you find this interesting, and if you are planning a China tour, that it helps with your plans. If you have any questions on the information you find in our China news, or on China travel, please feel free to contact us. Our team will do everything in its power to assist you.
Forest, waterfalls in Guilin attract tourists2013-07-08
Touristsstroll at Gudong forest scenic spot in Lingchuan County, Guilin City, south China's Guangxi Zhuang Autonomous Region, July 7, 2013. As high temperature hit most of China recently, the scenic spot with forest and waterfalls attracts large numbers of tourists from both home and abroad.
Inner Mongolia enters tourism peak season2013-07-08
Two horses play on a grassland near Hohhot, capital of north China's Inner Mongolia Autonomous Region, July 1, 2013. Inner Mongoliaembraces its tourism peak season recently. (Xinhua/Shang Jun)
Scenery of paddy fields in Yuanyang, China's Yunnan2013-07-03
Photo taken on June 29, 2013 shows paddy fields in Quanfuzhuang of Xinjie Town in Yuanyang, southwest China's Yunnan Province. With abundant rainfall, rice grows well this summer in the terraced fields here.
Angry Birds theme park under construction in E China2013-07-03
A worker is seen at an Angry Birds theme park in Haining, east China's Zhejiang Province, July 2, 2013. The Angry Birds theme park, the first of its kind in China, is under construction and is expected to open to the public in October. Angry Birds, created by the Finland-based Rovio Entertainment, is a popular game for smartphones and tablet computers.
Yellow River runs mainly in Heishan Gorge2013-07-03
The Yellow River flows in Zhongwei, a city in northwest China's Ningxia Hui Autonomous Region, June 29, 2013. The Yellow River, China's second longest which stretches for nearly 100 kilometers in Zhongwei, runs mainly in the Heishan Gorge.
Evening scenery in Guilin water system2013-07-03
This photo taken on June 27th shows the evening scenery of Guilin in southeast Chinas Guangxi Autonomous Region. The water system cruise has become one of Guilins top tourist attractions. It starts from Zhiyin Dock, which is on the east bank of Shanhu Lake, and goes via Shan, Rong, Gui, Mulong, which then joins the Li River, ending at the Liberation Bridge.
Beautiful Beijing - The Imperial Palace2013-07-01
The Imperial Palace, or the Forbidden City, was the palace of emperors in Ming and Qing Dynasties. Covering 720,000 square kilometers with more than 8 thousand rooms, the Imperial Palace is the largest and the most complete ancient architectural building complex in China. [Photo: CRIENGLISH.com/ Wang Zhi]
Amazing scenery of A'er Mountain, China's Inner Mongolia2013-07-01
Located at the foot of southwest Daxing'anling Mountains in North China's Inner Mongolia Autonomous Region, A'er Mountain is famous for its mineral springs, abundant volcanic lakes and beautiful forest. A'er Mountain means hot magic spring. The air here is so clear and pollution free. You can even hear the sound of snow falling because there is no noise.
Beer festival on Jinshan Beach2013-07-01
Blue sea, golden sand, girls in bikinis and live music - what more could you expect? There's also plenty of beer at the Shanghai Jinshan International Beer Festival starting tomorrow. The eight-day-long beer party at Jinshan District City Beach will feature traditional beers from Germany, Belgium and the Czech Republic. Some of the European breweries have operated for more than 300 years.
Photographic exhibition on Tibetan culture kicks off in New York2013-06-28
People visit a photographic exhibition on the culture and language of southwest China's Tibet Autonomous Region, which kicked off in New York, the United States, on June 26, 2013. (Xinhua/Wang Lei)
Mount Wutai home to 50 ancient Buddhist temples2013-06-28
Photo taken on June 26, 2013 shows a pagoda on Mount Wutai, one of four sacred Buddhist mountains in China, in north China's Shanxi Province. Added to UNESCO's World Heritage List in 2009, Mount Wutai is home to about 50 Buddhist temples built between the 1st century AD and the early 20th century. (Xinhua/Zhan Yan)
Bearer of Tibetan carpet in Qinghai2013-06-28
Fifty-one year old Yang Yongliang is an inheritor of the Jiaya Tibetan carpet, a state-level intangible cultural heritage, in Jiaya village, Huangzhong county, Northwest China's Qinghai province.
Lotus flowers blossom in China 's Hangzhou2013-06-26
Visitors enjoy seeing lotus flowers during an art festival along the West Lake in Hangzhou, capital of east China's Zhejiang Province, June 24, 2013. The festival will last till July 31.
Ancient town Lijiang in SW China braces tourism peak2013-06-26
Tourists visit the Old Town of Lijiang, southwest China's Yunnan Province, June 23, 2013. Lijiang hasreached the peak tourism season with the coming of the summer.
Beijing International Tourism Expo2013-06-26
Asia's leading annual travel and tourism event - Beijing International Tourism Expo (BITE) is backlarger and grander!
Tianshan inscribed on World Heritage List2013-06-24
The 37th session of UNESCO's World Heritage Committee (WHC) on Friday inscribed northwest China 's Xinjiang Tianshan natural site on the World Heritage List, the session's chairman declared.
Yamzhog Yumco Lake in Tibet2013-06-24
Photo taken on June 16, 2013 shows the scenery of the Yamzhog Yumco Lake in Lhokha prefecture, Southwest China's Tibet autonomous region.
Boys cool themselves off in river in Lhasa2013-06-19
Boys cool themselves off in a river in suburban Lhasa, capital of southwest China's Tibet Autonomous Region, June 17, 2013. (Xinhua/Purbu Zhaxi)
Picturing a different dream2013-06-19
All he had from his sojourn across China was a collection of more than 30,000 photos, and he had also started a blog. Rehage made a video with the photos and posted it online, where it chalked up millions of clicks. As more and more people became interested, a German publication asked him to write his story.
Take a visit to Yangtze River2013-06-19
Yangtze River is the longest river in Asia and third longest river in the world only after Nile in Africa and Amazon in South America. Rising high from the Tanggula range in Qinghai-Tibet Plateau, it flows for 6,418 kilometers eastward across most southern part of China.
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Andrew Eckford: The Blog
Not a real doctor since 2004.
Monday, April 22, 2013
Indefinite hiatus
I may as well admit that the blog is on hiatus for the foreseeable future. I've got plenty of things to write about, but no time. Sabbaticals, they are busy! Expect this situation to continue until at least the fall.
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The Security Seven: 7 Ways to Defend Your Factory from Today's Threats
ManufacturingAs they say, the best offense (i.e., growth) is a great defense (i.e. security). And while seven is considered a lucky number in many cultures, luck is NOT a security
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We're not going to crash? Do I really want to know? TMI!
ManufacturingA funny thing happened to me on the way to the fair. The Rockwell automation Fair that is.The Pilot comes on the intercom and says something like: "Hi, it's the
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Cisco at Automation Fair THIS WEEK! Meet Cisco Industry Experts in Chicago, 16th-17th.
Manufacturing"Chicago, Chicago, I'll show you around, You'll Stay Around", sings Frank Sinatra in the Fred Fisher song 'Chicago' published in 1922. Well, come to the McCormick Center in Chicago, Illinois
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Convergence Live: Cisco at Automation Fair, 16th-17th November 2011
ManufacturingAutomation Fair is just around the corner – two weeks from now. Convergence will be alive at AF this year. My colleagues Peter Granger and Andrew Lach have blogged about Cisco's
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Cisco at Rockwell Automation Fair, Chicago Illinois, 16th-17th November 2011
ManufacturingAutomation Fair is the largest gathering of Rockwell Automation users. With over 15,000 expected attendees this year, this is a can't miss conference for leading manufacturers, controls, operations and IT
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Bringing IT and Control together
ManufacturingAlthough not a rule, IT and Control at many manufacturers have an arms-length, if not more distant, relationship. They have different priorities, expertise and cultures. But the reality is that
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a matter of principle
Definition of a matter of principle
: a situation that requires something be done a certain way because one believes it is the only right way It was a matter of principle for her that she pay her own way. As a matter of principle, he would not accept the gift.
Word by Word Definitions
: a subject under consideration
: a subject of disagreement or litigation
: the events or circumstances of a particular situation
: to form or discharge pus : suppurate
: to be of importance : signify
: a comprehensive and fundamental law, doctrine, or assumption
: a rule or code of conduct
: habitual devotion to right principles
Seen and Heard
What made you want to look up a matter of principle? Please tell us where you read or heard it (including the quote, if possible).


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Oncology Best Practice™ Choosing Therapies for Patients with EGFR-Mutant Lung Cancers: More Options... More Decisions... Better Outcomes
Credit Designation
Physicians' Education Resource®, LLC is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians.Physicians' Education Resource®, LLC designates this live activity for a maximum of 1.5 AMA PRA Category 1 Credits™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.
Physicians' Education Resource®, LLC is approved by the California Board of Registered Nursing, Provider #16669 for 1.5 Contact Hours.
Acknowledgment of Commercial Support
This activity is supported by an educational grant from AstraZeneca.Oncology Best Practice™ Choosing Therapies for Patients with EGFR-Mutant Lung Cancers: More Options... More Decisions... Better Outcomes
Interested in hosting an Oncology Best Practice™ EGFR program? Contact Sara Shaughnessy at email@example.com or call (609) 378-3701. Click here to download the Educational Request Form. |
Oncology Best Practice™:
Choosing Therapies for Patients with EGFR-Mutant Lung Cancers: More Options... More Decisions... Better Outcomes
December 2016-July 2017
Click Here to View Upcoming Events
In patients with advanced non–small cell lung cancers (NSCLCs) and mutations in the epidermal growth factor receptor (EGFR) gene, the development of EGFR tyrosine kinase inhibitors (TKIs) has undoubtedly improved therapeutic outcomes. Nevertheless, resistance to these agents occurs, which generally manifests as disease progression after initial therapeutic response. With the wide range of choices available through multiple lines of therapy, decisions regarding the best initial treatment, when to rebiopsy and/or retest for molecular markers (and the method by which to do so), selecting the best approach at the time of acquired drug resistance, and managing central nervous system (CNS) metastases are key in the care of these patients.Accordingly, there is a need for educational activities in the community that illustrate how to navigate the nuances regarding the evaluation of acquired resistance, newer approaches to molecular testing, and choosing subsequent approaches to therapy. To meet these educational needs, this series of programs has recruited national experts who can synthesize recent data sets on newly available and late-stage investigational strategies to manage EGFR-mutated, advanced NSCLCs, and who can help place new evidence in its proper context for the practitioner challenged to manage patients with these tumors.
Key topics to be addressed include:
- Choosing the best initial therapy for patients with EGFR-mutated, advanced NSCLCs
- Best practices for molecular characterization of acquired resistance, including plasma- and tissue-based assays
- Optimal choice and timing of therapy in the second-line and beyond
- Current and emerging approaches to managing CNS metastases associated with EGFR-mutated NSCLCs
- Managing adverse events of therapy
Target Audience
This educational activity is directed toward medical oncologists who treat patients with lung cancers. Nurse practitioners, nurses, physician assistants, pharmacists, researchers, and other health care professionals interested in the treatment of cancer will be invited to participate.Educational Objectives
Upon completion of this activity, participants will be able to:- Detail evidence that underlies the application of optimized front-line strategies to manage EGFR-mutated, advanced non–small cell lung cancers (NSCLCs)
- Describe methods to optimize EGFR subtyping and emerging technologies that can practically facilitate tumor testing, as well as overcome inherent challenges to optimized testing in community settings where advanced NSCLCs are managed
- Explain how to optimize the timing of clinical interventions in the relapsed, advanced NSCLC setting and the trial evidence that informs decision making to treat patients with EGFR-TKI resistance
- Address treatment-related toxicities and methods to optimize the management of CNS metastases in the care of patients with advanced NSCLCs.
Program Chair
MARK KRIS, MDAttending, Thoracic Oncology Service
William and Joy Ruane Chair in Thoracic Oncology
Memorial Sloan Kettering Cancer Center
New York, NY
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The original material synthesised had an ABA structure comprising of blocks of 2-hydroxypropyl methacrylate (HPMA) and 2-(methacryloyloxy) ethyl phosphorylcholine (MPC).An analogous graft-copolymer has been synthesised where PHPMA chains have been attached onto a PMPC chain via RAFT polymerisation, a form of controlled free-radical polymerisation used frequently by the research group of Professor Steve Armes in the Department of Chemistry. As well as this, AB diblock copolymers of the same monomers have been synthesised and shown to form self-assembled 'worm-gels'. This novel material is biocompatible and has also been used in this study to determine if it is due to the gel property of polymers with this composition which leads to their antimicrobial properties.
Biological assays with staphylococcus aureus have been carried out on all of these PHPMA-PMPC materials to determine more about the mechanism of antimicrobial activity. Results have shown that the 'worm-gels', although biocompatible gels, were not antimicrobial. However, the graft copolymer gels have been shown inhibit bacterial growth and further studies by transmission electron microscopy show that this is likely due to the hydrophobic PHPMA chains in the gel penetrating and therefore causing damage to the bacterial membrane. Another interesting property of this graft copolymer gel is its thermoreversible gelation behaviour, making it applicable in the formation of antibacterial smart wound dressings.
Original article: Antimicrobial Graft Copolymer Gels. A. C. Harvey, J. Madsen, C. W. I. Douglas, S. MacNeil, S. P. Armes, Biomacromolecules, 2016, 2710-2718
Article by Rheanna Perry; a PhD Student on the EPSRC Polymers, Soft Matter and Colloids CDT programme. For more information, please contact Dr Joe Gaunt at the Polymer Centre.
(1) Madsen, J.; Armes, S. P.; Bertal, K.; Lomas, H.; MacNeil, S.; Lewis, A. L. Biomacromolecules 2008, 9 (8), 2265–2275.
(2) Bertal, K.; Shepherd, J.; Douglas, C. W. I.; Madsen, J.; Morse, A.; Edmondson, S.; Armes, S. P.; Lewis, A.; MacNeil, S. J. Mater. Sci. 2009, 44 (23), 6233–6246.
(3) Harvey, A. C.; Madsen, J.; Douglas, C. W. I.; MacNeil, S.; Armes, S. P. Biomacromolecules 2016, 17 (8), 2710–2718.
]]>Oleksandr Mykhaylyk et al. recently reported a new technique, shear-induced polarised light imaging (SIPLI), which combines rotational rheology with a reflection polariscope in order to study the behaviour of macromolecules and nanoparticles through changes in the birefringence properties of a material. Birefringence occurs when there is shear-induced orientation of particles which creates optical anisotropy. Birefringent materials change the orientation of the polarised light used to illuminate the sample, allowing it to pass through an analyser which is orthogonal to the axis of polarised light. The result of shear-induced orientation is a characteristic Maltese cross pattern. Conversely, non-birefringent samples do not change the orientation of plane-polarised light and thus the resulting polarised light image appears dark.
One application for SPILI presented by Mykhaylyk et al., is for the study of thermo-responsive block copolymer micelles. A number of particle morphologies can be produced from the self-assembly of amphiphilic block copolymers in a solvent selective for one of the blocks. These include spheres and vesicles, which form free-flowing liquids, and worms, which form free-standing physical hydrogels. Unlike the non-birefringent nature of the sphere and vesicle morphologies, the uniaxial anisotropy of the worm morphology results in birefringence. Consequently, the thermo-reversible worm-to-sphere transition, and associated reversible de-gelation, of a poly(glycerol monomethacrylate)-block-poly(2-hydroxypropyl methacrylate) hydrogel is an ideal system for SIPLI characterisation.
The rheology data presented in the study confirms the expected reduced viscosity on cooling to 5 °C associated with degelation during the worm-to-sphere morphology transition. Simultaneously, a loss of the Maltese cross pattern is observed due the formation of isotropic spherical particles. On heating, the opposite sphere-to-worm transition occurs resulting in the reappearance of the Maltese cross pattern and an increase in viscosity due to regelation. Here, SIPLI has allowed the study of structural-rheological property relationships of thermo-responsive block copolymer micelles. This demonstrates just one application of SIPLI, with many other advantages and applications of SIPLI discussed in the original article.
Original Article: Applications of Shear-Induced Polarized Light Imaging (SIPLI) Technique for Mechano-Optical Rheology of Polymers and Soft Matter Materials O. O. Mykhaylyk, N. J. Warren, A. J. Parnell, G. Pfeifer and J. Laeuger, J. Polym. Sci. Part B Polym. Phys., 2016, 1–20.
Article by Sarah Byard; a PhD Student on the EPSRC Polymers, Soft Matter and Colloids CDT programme. For more information, please contact Dr Joe Gaunt at the Polymer Centre.
]]>A team of researchers from the University of Sheffield's Department of Mechanical Engineering, including Polymer Centre academic Dr Rachel Tomlinson, have recently developed a method for creating repeatable pre-cracked polymer specimens for fracture testing.
Currently, specimens are prepared manually using a razor blade to create a small pre-crack from a notched sample. These samples are then tested to destruction to obtain fracture properties of the material. The procedure is heavily dependent on the operator and produces pre-cracks of varying length, angle and crack-front shape; all of these factors affect the repeatability and reliability of the subsequent test, as well as posing several safety concerns.
Using a technique first proposed by Tamura et al.[1], Dr Tomlinson's team developed a methodology to produce consistent pre-cracks that meet the requirements of the various test standards for measuring fracture toughness. The technique involves applying loading in 2 directions; a tensile load to propagate a crack from the notch manufactured during specimen creation, and a compressive load applied across the width of the specimen at the desired distance from the notch to act as a barrier to further crack growth (Figure 1). A variety of compressive loads were investigated to find a suitable load for the test material which prevented crack propagation past the desired length, without causing the crack to then travel parallel to the direction of the compressive load. Once this was established, 40 test samples were prepared using this method and the pre-crack length and shape recorded. The results showed that the developed method was very repeatable, with 35 of the specimens accurate to within 10 microns of the desired crack length. A comparison of the crack fronts produced using the current and proposed methods showed that the developed method also produces a significantly straighter crack front, minimising the need to average the crack length across the width of the specimen and saving additional time.
Original Publication: Nithiananthan Kuppusamy, Rachel A. Tomlinson, Repeatable pre-cracking preparation for fracture testing of polymeric materials, Engineering Fracture Mechanics, Volume 152, February 2016, Pages 81-87, ISSN 0013-7944
Article by Ryan Brown; a PhD Student on the EPSRC Polymers, Soft Matter and Colloids CDT programme. For more information, please contact Dr Joe Gaunt at the Polymer Centre.
[1] Tamura K, Hasjimoto S. A precrack introducing method in CT-specimens for measuring KIC values of brittle materials. In: 15th International conference of experimental mechanics. ICEM15. Portugal; 2011. p. 7
]]>Investigation into microbubble formation is essential in order to fully utilise their properties in applications. Many features of bubble formation have previously been explored and have been found to have a large impact, these include pore size and orientation, and flow rate. The university and Polymer centre academic Dr Jonathan Howse et al. present an investigation into how the wettability of the diffuser surface impacts upon the dynamics of bubble formation process. Effects were studied at the orifice as well as upon the resultant bubble cloud produced by the wetting variations. The study comprises a thorough investigation into bubble formation by examining bubbles formed from a single pore, multiple well-defined pores, and sintered diffusers with a random network of pores.
Various surfaces were investigated during the course of this study which displayed contact angles from 107.9° to 13.1°. It was found that when a surface displays a contact angle lower than 90° the bubbles that are emitted are significantly smaller than those emitted from a surface with a contact angle above 90°. This data indicates that a contact angle of 90° is a switching point where the bubble size vastly changes.
Original article: Influence of Surface Wettability on Microbubble Formation, D. J. Wesley, R. M. Smith, W. B. Zimmerman, J. R. Howse, Langmuir, 2016, 32, 1269-1278.
Article by Thomas Neal; a PhD Student on the EPSRC Polymers, Soft Matter and Colloids CDT programme. For more information, please contact Dr Joe Gaunt at the Polymer Centre.
]]>Recent work by Biqiong Chen and Shelia MacNeil at the Polymer Centre, in collaboration with various researchers, have harnessed the narrow spectrum emission of quantum dots for the potential of medical imaging alongside drug delivery and photothermal therapy.
The GO quantum dots, composed of reduced graphene oxide-iron oxide, combined the superparamagnetic properties of iron oxide with the drug loading capabilities of graphene oxide. The quantum dots were found to be inherently photoluminescent and superparamagnetic alongside being biocompatible making the materials ideal for use as medical devices.
Photoluminescence is useful in providing detection of the materials by fluorescent imaging. Superparamagnetism allows the magnetic moment of the quantum dots to be changed on a nanoscale. Hence, drug release from quantum dots can be stimulated by applying an external magnetic field for targeted drug delivery. Superparamagnetism also allows imaging by magnetic resonance imaging (MRI) to aid the visualisation of tumours and image guided surgeries.
The GO quantum dots were loaded with the model drug lidocaine hydrochloride. The loading ratio of drug to quantum dots was 0.31:1 which was fully released in phosphate buffered saline solution over 8 hours indicating efficient drug elution.
Testing of the GO quantum dots over a range of concentrations with varying laser powers showed a maximum temperature increase of 50 °C. This large temperature increase would be useful for treating tumours by photothermal therapy, where heat is applied directly to tumours to damage the cancerous cells.
Original article: Photoluminescent and superparamagnetic reduced graphene oxide-iron oxide quantum dots for dual-modality imaging, drug delivery and photothermal therapy, R. Justin, K. Tao, S. Román, D. Chen, Y. Xu, X. Geng, I. M. Ross, R. T. Grant, A. Pearson, G. Zhou, S. MacNeil, K. Sun and B. Chen, Carbon N. Y., 2016, 97, 54–70.
Article by Jasmine Lord; a PhD Student on the EPSRC Polymers, Soft Matter and Colloids CDT programme. For more information, please contact Dr Joe Gaunt at the Polymer Centre.
]]>In the study, the feathers were imaged using both optical and electron microscopy, although the most significant results were obtained by scanning with Small Angle X-ray Scattering (SAXS). This technique allows non-destructive probing of the nanoscopic length scales relevant to the optically-active structures. The colours of the feathers could be correlated to the size of the beta-keratin domains in the scattering structures, and it was shown that the variation in colour seen along individual barbs on the feather was due to continuous variation of the dimensions of the keratin 'sponge'. However, the exact biological mechanism which allows this degree of control during the feather's growth is still unknown.
Their results also help explain why non-iridescent green colours in the natural world are rarely generated by structural elements alone, despite being obviously useful for camouflage. The keratin structures were found to scatter relatively broad portions of the spectrum: 'structural blue' can be obtained by scattering the blue and the non-visible, ultraviolet portions of the spectrum, and 'structural white' can obtained by scattering light across the whole of the visible spectrum, but green light occupies too narrow a set of wavelengths to be scattered selectively. However, one solution to this is to use a combination of 'structural blue' and yellow pigment, with the green tree frog being a good example.
Original publication: Parnell, A. J., Washington, A. L., Mykhaylyk, O. O., Hill, C. J., Bianco, A., Burg, S. L., Parker, A. R. (2015). Spatially modulated structural colour in bird feathers. Scientific Reports, 5, 18317. http://doi.org/10.1038/srep18317
Article by Rhys Williams; a PhD Student on the EPSRC Polymers, Soft Matter and Colloids CDT programme. For more information, please contact Dr Joe Gaunt at the Polymer Centre.
]]>Researchers from the Universities of Sheffield and Warwick have found that using a block copolymer hydrogel, which forms a soft 3D network of nanometer-sized worms in water, prevents damage to red blood cells that have been frozen at low temperatures for long periods of time.
This research has the potential to make blood transfusions easier as blood can normally, only be stored for up to 42 days without using cryopreservation (freezing) techniques.
Freezing red blood cells usually requires the addition of potent cryopreservatives that can have undesirable side-effects, while thawing imposes enormous stresses on the cells.
Freezing is currently the best way to store red blood cells. However, various anti-freeze compounds are normally added to prevent damage during freezing due to ice crystal formation. Removing such additives from cells can be problematic but now scientists have found a promising new synthetic alternative.
Steve Armes, Professor of Polymer and Colloid Chemistry, at the University of Sheffield said: "Our new material is a biocompatible long-chain molecule that self-assembles in water to give a network of worm-like particles that form a soft gel. This provides a suitable matrix for freezing red blood cells for their long-term storage.
"The most important property is its cryoprotection performance. This is the first demonstration that a wholly synthetic formulation can be used to achieve efficient cryopreservation of red blood cells."
When used alone, the worm-like particles do not afford any protection, but when used in combination with a second biocompatible polymer that prevents ice crystal formation, then up to two-thirds of the red blood cells survive thawing.
The worm gel not only facilitates cryoprotection of red blood cells, but may also serve as a suitable matrix for tissue engineering.
This suggests an attractive one-pot solution for whole blood cryopreservation and tissue engineering applications.
The study, led by Professor Armes and Professor Matthew Gibson from the University of Warwick, is published in the journalAngewandte Chemie.
]]>Similarly, the ability of certain polymers to self-assemble in solution to form hollow spheres, known as vesicles or polymersomes, provides us with a convenient vessel within which to encapsulate desired active ingredients. These vesicles contain an inner lumen encased by a spherical polymeric bilayer, somewhat similar to the way eukaryotic cells are encased by a lipid bilayer.
In the recent work reported by Professor Armes, the particular block copolymer used to produce these vesicles was poly(glycerol monomethacrylate)-poly(2-hydroxypropyl methacrylate), which abbreviated to PGMA-PHPMA. The use of a technique known as polymerisation-induced self-assembly (PISA) enabled the convenient synthesis of these PGMA-PHPMA vesicles at relatively high concentrations and short reaction times.
Poly(2-hydroxypropyl methacrylate) has an unusual property: in water it becomes more soluble at lower temperatures. Furthermore, by cooling a solution of PGMA-PHPMA vesicles down to around 0 °C, the PHPMA block becomes increasingly solvated which causes the vesicles to break apart. The ability to disintegrate the encapsulating vesicles by cooling provides a convenient thermal trigger to release any payload that may be loaded within them. By cooling the silica loaded vesicles in ice for 30 minutes, it was demonstrated that the vesicles disintegrated and the silica nanoparticles were released back into solution.
The encapsulation and release process was characterised by a number of analytical techniques, including transmission electron microscopy (TEM), disc-centrifuge photosedimentometry (DCP) and small-angle x-ray scattering (SAXS). In addition, this encapsulation process was not limited to inorganic silica nanoparticles; biological material could also be encapsulated. Bovine serum albumin (BSA), a model globular protein, was successfully encapsulated in the PGMA-PHPMA vesicles and then released upon cooling.
For the original publication please see C. J Mable, S. P. Armes et al. J. Am. Chem. Soc. 2015, 137, 16098 or visit http://pubs.acs.org/doi/abs/10.1021/jacs.5b10415
Article by Matt Rymaruk; a PhD Student on the EPSRC Polymers, Soft Matter and Colloids CDT programme. For more information, please contact Dr Joe Gaunt at the Polymer Centre.
]]>Just six months into the three-year Engineering and Physical Sciences Research Council (EPSRC) funded project, the Sheffield team have already made a number of discoveries with the potential to transform human stem cell research and aid the development of the next generation of healthcare technologies for a wide range of diseases and conditions.
"Human pluripotent stem cells offer tremendous possibilities for combating a range of medical conditions and diseases," says Professor Steve Armes, Director of the Polymer Centre and the Principal Investigator on the project.
"However, a major challenge is to optimise stem cell manufacture with excellent reproducibility to meet the requirements of cell biologists, the biotech industry and clinicians. Well-defined and consistent conditions for long-term stem cell culture, storage and the easy harvesting of stem cells are essential to success."
Armes who is a fellow of the Royal Society has more than 500 published papers to his name, and 26,000 citations, believes the fundamental scientific research he and his interdisciplinary team are conducting will "play an important role in delivering affordable healthcare solutions for patients over the next 10-50 years."
"Human stem cells are at the forefront of biomedical research and clearly have enormous therapeutic potential for diabetes, age-related blindness, spinal cord injuries and Parkinson's disease," he added.
While Armes and his chemistry colleagues have been able to develop the novel polymer gels, the project's success is built on close collaboration with Professor Harry Moore, co-director of the Centre for Cell Biology in Sheffield, whose team also co-ordinate the International Stem Cell Initiative, a global consortium of laboratories that define standards in this field.
"Chemists and biologists talk very different languages," says Armes. "But we have overcome the communication barrier and the team works really well together."
Dr. Nick Warren, a post-doctoral chemist, has produced the long worm-like strands that interact to form a soft, freestanding aqueous gel. This highly biocompatible, easily sterilised by filtration and de-gels reversibly on cooling below ambient temperature. Human embryonic stem cells immersed in such gels can survive for up to 14 days at 37oC. Dr. Irene Canton, a biochemist working with Moore, has found that human embryonic stem cells gradually 'go to sleep' when immersed in the gel, and slowly 'wake up' when removed from the gel.
"Our worm gel is a convenient and inexpensive medium for the long-term storage of pluripotent human stem cells. It could potentially replace existing unsatisfactory animal-derived products and enable the acceleration of stem cell biology research, ultimately leading to new clinical therapies," Armes said.
Although he is mainly focused on basic research, Prof. Armes is equally passionate about technology transfer – he is a named inventor on more than 20 patents, including a commercially successful anti-reflective coating for solar panels. His nanoparticle research has also inspired the development of dirt-shedding paints on the external facades of buildings.
Article reproduced from Discover Magazine.
The cross-links between polymer chains can be either physical or chemical. Physically cross-linked gels tend to be weak and the physical cross-links between the polymer chains are reversible. The weak mechanical properties limit the use of physically cross-linked gels in wider applications.
Chemically cross-linked gels are formed following a chemical reaction, where a chemical cross-linking agent is added to a solution of polymer chains. By varying the quantity of cross-linking agent, the degree of cross-linking can be altered to optimise the gel properties for different applications. Although chemically cross-linked gels have attractive properties, the toxicity of cross-linking agents limits their use in biomedical applications.
Polymer centre academic Dr. Biqiong Chen has attempted to overcome these boundaries by synthesising novel, physically cross-linked, graphene oxide (GO)-gelatin nanocomposite hydrogels by self-assembly.
Both gelatin hydrogels and graphene-based materials have previously been studied for applications in drug delivery and tissue engineering. Gelatin is a denatured biopolymer, derived from collagen (found in skin and muscle). It has advantageous properties such as being biocompatible, biodegradable and low cost. GO, the oxidised form of graphene, has low toxicity. Gelatin-functionalised GO nanosheets are non-toxic and can be removed from the body by metabolism. Although these gels are physically cross-linked, multiple hydrogen-bonding and electrostatic interactions between the gelatin chains and GO sheets increase the strength of the 3D network significantly. These gels also exhibit self-healing properties.
The GO-gelatin hydrogels are also pH responsive and can be used for pH-sensitive drug release. At acidic pH (pH 1.7) the GO sheets form tightly packed aggregates preventing drug release. At neutral pH (pH 7.4) the pore size increases, promoting the diffusion of an encapsulated drug from the hydrogel to its surrounding liquid environment. This pH-sensitive behaviour would allow selective drug release into the intestine (pH 6.6-7.5) with minimal release in the stomach (pH 1.0-2.5). Conventional drug delivery methods can carry drugs to a specific location but are unable to protect the drug against the acidic and enzymatic environment of the stomach which can lead to the drug being released early or being altered. In contrast, these GO-gelatin hydrogels can protect the drug from enzymatic attack in the stomach. This allows the drug to be maintained and then released in a more controlled manner.
This research was published by Dr Biqiong Chen's research group in the Journal of Polymer Science Part B and was supported by the University of Sheffield. Original Article: Y. Piao, B. Chen, J. Polym. Sci. Part B: Polym. Phys, 2014, 53, 356 -367.
Article by Amy Cockram; a PhD Student on the EPSRC Polymers, Soft Matter and Colloids CDT programme. For more information, please contact Dr Joe Gaunt at the Polymer Centre.


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text:
3DOcean Magis Chair One Public Seating System 2 305098
3DOcean Magis Chair One Public Seating System 2 305098
3D Model \ Furnishings \ Seating
Outdoor \ Modern \ Plastic \ Public \ Seating \ Seat \ Metal \ Magis \ Furniture
3D Model - Magis Chair One Public Seating System 2 305098 by modelplusmodel @ 3DOcean
3D Model \ Furnishings \ Seating
3D File Formats Included: .3ds (multi format), .dxf (multi format), .fbx (multi format), .max (3ds Max), .obj (multi format); Animated: No; Created In: 3ds max 2008; Geometry: Polygons; Materials: Yes; Poly Count: 67500; Rigged: No; Textured: No; UV Layout: No.
Great 3D model of a Chair_One Public Seating System 2 by Magis. Design: Konstantin Grcic. The model is based on the manufacturer's original dimensions and was created paying much attention to all the details of the real chair. It has accurate grid, ready to use and perfect for close-up. You will get 3 different variations of seating system: 195 cm wide with 3 chairs; 265 cm wide with 3 chairs and a table; 335 cm wide with 4 chairs and a table. The chair system is made of separate elements, so it's easily to create any combination you need. Available in 3 colors: red, black and white.
Available formats.
.max v-ray – with materials and textures
.max scanline – with materials and textures
.3ds – simple object without materials (with mapping and textures included)
.obj – simple object without materials (with mapping and textures included)
.fbx – simple object without materials (with mapping and textures included)
.dxf – simple object without textures and materials
This model is one of other great models that goes together in the Vol.02 Chairs+tables. The Volume you may find on our website www.modelplusmodel.com .
Flos Tab floor and table lamps; Artemide Soffione lamps; Louis Poulsen PH 4/3 lamps; Louis Poulsen PH Snowball suspension lamp; Louis Poulsen PH Artichoke suspension lam; George Nelson Saucer suspension lamp; Lightyears Atomheart suspension lamp.
Keywords: armchair, chair, design, furniture, garden, grcic, interior, italian, magis, metal, modern, one, outdoor, plastic, public, seat, seating.


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5 Star Gourmet Sauce for Steak
This sauce was like heaven had come to my lips. I used it on a freshly peppered steak which was an experience. This is now my favourite sauce. It is more...
tomato, sherry, vegetable oil, paprika, black pepper, salt, tomato sauce, water
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Cinnamon Chicken Stew
Found on another site, looks pretty interesting
black pepper, cinnamon, vegetable oil, salt, tomato sauce, water, tomato, +adobo seasoning, +chicken, +smoked ham
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paprika, cinnamon, salt, black pepper, tomato, tomato sauce, water, +sirloin steak, +onions, +celery, +garlic, +chili, +basil, +oregano, +thyme, +cayenne, +cumin, +red pepper flakes, +allspice, +pasta, +cheddar cheese, +red kidney beans
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Grilled Chicken/Chocolate Chili
Everything can be prepared the night before, grilling the chicken and adding to the chili before serving. In fact it's better that way. It presents well...
cinnamon, vegetable oil, black pepper, salt, tomato, tomato sauce, water, +black beans, +chicken, +cilantro, +cumin, +red kidney beans, +garlic powder, +green pepper, +olive oil, +onions, +red pepper, +cocoa powder
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Chilies Rellenos Con Picadillo
What a way to say stuffed peppers! Prep time does not include the charring and resting of the peppers (20 minutes).
sherry, cinnamon, salt, tomato sauce, tomato, vegetable oil, water, +flour, +eggs, +cilantro, +ground beef, +cloves, +cumin, +green chilies, +onions, +sugar, +toasted almond, +vinegar
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vegetable oil, water, tomato sauce, tomato, paprika, salt, black pepper, +alligator meat, +flour, +onions, +green pepper, +garlic, +parsley, +cayenne, +bay leaves, +sausage, +butter, +rice
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What could be better than having Mexican night at home, filling up your tacos with all the best ingredients? How about a dessert taco?!!
It may look complicated but it is super easy to create and delicious to eat, with handmade tortillas. Some are even made out of a cookie dough! This dessert is all about being creative and having fun with food!
We hope this inspires you as much as it does us to hop in the kitchen and get creative.
Let us know on our Facebook page if you've attempted to make your very own dessert taco!


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Reviews (0)
Harken's Standard Swivel Cam Base is ideal for mounting in the cockpit for use on larger keelboats and small offshore boats that use (2 1/4 in) 57mm and (3 in) 75mm plastic blocks, including ratchet blocks, that accept line with a maximum diameter of ᄑヤ (12.7mm). This standard configuration has a tall arm, stand-up spring and U-adaptor to accept a variety of appropriate blocks. Its swivel features dual rows of Delrin ball bearings that swivel freely even under high loads.


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variety.com –
"Glee" co-producer Roberto Aguirre-Sacasa is in talks to adapt Megan Shepherd's upcoming young adult novel "Madman's Daughter" for Josh Schwartz and Stephanie Savage's Fake Empire banner.
Created by brucelee
5 years 3 weeks ago
About brucelee
Bruce Lee needs no introduction, but no one should mistaken the Martial Arts screen legend for our own brucelee. For some unknown reason, he despises Chinese spareribs.


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My rantings and ravings about all things ALM
There are a lot of conferences in Chicago this summer, well I suppose technically it's still spring but from these temps you'd never know it! Anyway, I was invited to speak at Chicago Coder Conference this year (not to be confused with the awesome CCC = Chicago Code Camp conference), and I'd never really considered it before. With all of the other conferences I am involved in and speaking at, it just hadn't made the cut. I recently checked out their session list and holy cow are there some great people speaking, including a few of my coworkers. There is even a full day of hands-on sessions where you can dig in deep. It's an seriously action-lacked 3 days. A few of the bigger names you might recognize are Doc Norton, Uncle Bob Martin, and Joel Tosi.
Now I'd be remiss if I didn't bring up the great topics being presented by some of the folks at Polaris Solutions, including yours truly:
Steven Contos
Room 600 from 10:00 AM - 11:00 AM
Florin Ciobanu
Room 621 from 10:00 AM - 11:00 PM
Kevin Fitzpatrick
June 6, 2016 - Session 4 – Dear Coder: The Problem is Over Here!
Room 600 from 2:30 PM - 3:30 PM
Angela Dugan
June 7, 2016 - Lunch & Learn – Improve your Retrospectives with Agile Kaizen!
Room 621 from 12:15 PM - 1:15 PM
June 7, 2016 - Session 4 – Deconstructing the Scaled Agile Framework
Room 404 from 2:30 PM - 3:30 PM
It's not too late to sign up, and I may still have some discount codes I can share if you want to get in on it. If you are interested, hit me up through the contact link on my blog for more info!
And while you're in the mood to check out AMAZING local conferences, be sure to check out ThatConference! I wrote a blog post about it here, including a great overview and some pictures. Check it out. Hope to see you at Chicago Coder Conference next week, and at ThatConference in August!
.NET | Agile | Application Lifecycle Management | Architecture | Chicago Code Camp | Continuous Delivery | DevOps | Mobile development | Mobile | Process Methodology | Product Development | SDLC | Scrum | SAFe | ThatConference | Visual Studio | Visual Studio Team Services | career growth | technology | soft skills | retrospectives | Xamarin
In case you missed it, Update 2 for both Visual Studio 2015 and TFS 2105 were announced at //Build yesterday! Be sure to download it and check out the new features as soon as you get a chance, you won't regret it J One of the biggest changes in TFS 2015 is the new build system. It can be a bit overwhelming to get ramped up on all of the new features, so this next meeting will be a great way to get your feet wet.
Getting Started with Team Foundation Server 2015 Build
Team Foundation Server (TFS) has a powerful build system for years. Nevertheless, TFS 2015 introduces a completely new system. Wondering what this is about and why (again) belongs to something new to you? Join us to explore the next generation of TFS build system and learn more about the background, the technical implementation and the benefits (eg, Cross-Platform builds).
Please note - Many people have requested an earlier starting time, so we're giving it a try. Dinner now starts at 6:00pm and the presentation will start at 6:30pm. See you there!
Speaker Bio:
Paul Hacker has over 15 years of application architecture, design, development, and management expertise in Microsoft technologies. Paul has a depth of experience in ALM, Process Improvement, and Team Foundation Server. Having distinguished himself as a leader in the IT industry he has been awarded the distinction of Microsoft MVP in the ALM category every year since 2006. Over the years Paul has proven his expertise in Application Lifecycle Management and has demonstrated his professionalism and commitment to the continuous process of managing the life of an application through governance, development and maintenance.
Check out Paul's blog, and listen for him sharing exciting VSTS/TFS news and updates on the RadioTFS podcast!
Agenda:6:00 Dinner and networking, 6:30pm Main Presentation
*I know parking is pricey in the city so please don't overpay for it. SpotHero has some great parking very near to the Aon Center for as little as $10, I use them and I love the service!
P.S. Don't forget to register, Aon center security requires it.
TFS | TFS 2015 | Team Foundation Server | Build Automation | Continuous Delivery | Continuous deployment | Continuous improvement | Visual Studio | Visual Studio 2015 | Visual Studio Team Services | Con | vis
Everyone seems to be asking for "better DevOps" these days, but admittedly it's hard to pin down exactly what that means, and to complicate things even more, it seems to mean different things to different people. Is it about people? Is it about processes and practices? Is it about tools? Is it about culture? Yes, all of these things and more!
This event is focused on some great tools and a few key practices, because we only have 4 hours and we'd probably need a week to tackle everything we'd really like to :) We'll be talking about Team Foundation Server and Visual Studio Team Services, Visual Studio, Microsoft Azure, Application Insights, and even some tools you might not expect at a Microsoft event like SonarQube, Octopus Deploy, and Chef! Because let's be honest, our tool belts are overflowing these days, and sometimes it's hard to know which ones are the best one for the job. To that end, we've assembled a fantastic team of local MVPs and technical community leads with loads of experience tackling the various challenges that we all face in the quest for "good DevOps", whatever that means. Check out the agenda below to see more details about what topics they'll be talking about, and be sure to stick around for the raffle of a Microsoft Band 2!
As an added bonus, we're even buying you breakfast! Real breakfast too, with bacon, sausage, eggs, and OJ, not just bagels and coffee. Seating is limited, so please be sure to register to secure your spot today.
This event is being organized and run by some of most passionate folks in the community that I know including Angela Dugan(me!), Chris Taylor, Eric Boyd, Greg Levenhagen, Jim Szubryt, Landan Rotter, and Min Maung. Join us next month for this free, half day event in downtown Chicago to explore DevOps and Azure!
Head on over to Eventbrite today for more details and to get registered!
Application Lifecycle Management | ALM | DevOps | Azure | Cloud Computing | Continuous deployment | Continuous Delivery | Application Insights | community | Visual Studio 2015 | Visual Studio Team Services | Visual Studio | Team Foundation Server | TFS 2015 | TFS | Software Development Lifecycle Management | Release Management | Powershell | Environment Provisioning | DSC
You heard me correctly, mainstream support for TFS 2010 ends on July 14th, less than 6 weeks from today! So if you're thinking "it still WORKS, why should I upgrade?" Consider these points…
The good news is that you may qualify for up to $5,000 worth of free services to help you plan and prepare for your upgrade through the Microsoft Deployment Planning Services program (DTDPS)! Wondering what that is? Below is a quick FAQ that I created to explain the program:
Now what exactly IS DTDPS? Well first of all it's a Microsoft offering, so expect MANY acronyms to follow. DTDPS stands for Developer Tools Deployment Planning Services. Specifically, the development tools that these services are meant to be used in conjunction with are the Microsoft Visual Studio ALM platform - Team Foundation Server, Visual Studio, and Microsoft Test Manager (TFS, VS, and MTM for good measure).
So what does this really do for me? While most people are already very familiar with Visual Studio from a .NET development perspective, many people who own the other tools within the TFS platform are not taking full advantage of them. DTDPS is the solution to this problem, connecting customers with the right partners to make sure they are getting the full value of their ALM investment. Software that sits on the shelf is a huge waste of money. And from Microsoft's perspective is something you're not likely to buy again, so it is of course in their interest to offer such a program.
What kinds of services are included in DTDPS? Currently there are 4 DTDPS offerings available: TFS deployment planning assessment, Visual Studio Quality Tools assessment, Visual Studio Agile Deployment Assessment, and Visual Studio DevOps Deployment Assessment. You'll notice a theme here, the word "planning". These engagements are not meant to be used to implement the tools. Instead, they are short, fixed-length (3 and 5 days) engagements for gathering data and analyzing your current environment and needs in order for us to help you build a plan for implementation and adoption of Visual Studio and TFS ALM tooling. It's a great kickstart and will drastically accelerate your ALM initiatives.
But what if I don't need one of those services, but need other assistance with TFS? Well, it depends. I know, I know, typical consulting answer. These programs can be expanded upon to assist customers with other ALM related concerns, so drop me a line at the email I provide below, and I'll be happy to discuss it with you in more detail.
Who delivers the engagement? DTDPS is a program delivered through certified and experienced ALM partners like Polaris Solutions to help customers with SA (Software Assurance) benefits to take full advantage of the tools they own. We have delivered dozens of these engagements over the past few years and every customer we have worked with has been extremely happy with the valuable roadmaps that we delivered. You will benefit from a wealth of relevant experience and proven ALM practices that only comes from us having deployed and leveraged the tools in a large number of different environments and business verticals.
OK, I'm intrigued, but how expensive is it? It is FREE. Seriously, and absolutely. This benefit is available to customers who purchase Microsoft products with SA, think of it as a rewards program. In fact, you may have DTDPS credits without knowing it! Many of the customers I work with did not know they had DTDPS credits available until I turned them onto the program.
I want in! How do I sign up? Start at the DTDPS site. Here you can peruse the various services available and see which ones are right for you and your organization. Then check out the DTDPS QuickStart guide which walks you through the steps of accessing your benefits. Then you just pick a partner to work with, like us, and you're on your way to a better way of doing ALM!
If you are interested in learning more about DTDPS, or if you would like to find out more about getting a free quick assessment of the effort required to upgrade and the benefits that your team would enjoy, please contact me at firstname.lastname@example.com. And if you know anyone still using an older version of TFS (anyone running TFS 2013 or earlier qualifies) help them out and point them to this blog!
Application Lifecycle Management | Agile | Automated Testing | Build Automation | ALM | Continuous Delivery | Continuous deployment | Deployment | Deployment Planning | DTDPS | DevOps | Lab Management | MTM | Microsoft | Microsoft Test Manager | Microsoft Test Professional | Performance testing | Process Methodology | Process Templates | Quality Assurance | Release Management | Requirements Management | SDLC | Software Testing | TFS | TFS 2008 | TFS 2010 | TFS 2013 | TFS 2012 | TFS 2015 | TFS Administration | TFS Migration | TFS Service | TFS Upgrade | Team Foundation Server | Test Automation | Test Case Management | Testing | VS 2010 | VS 2012 | VS 2013 | VS 2015 | VSOnline | Visual Studio | Visual Studio 2012 | Visual Studio 2013 | Work Item Tracking | development
When: Wednesday, February 18, 2015 from 6:30 PM to 9:00 PM Where:Microsoft-Chicago 200 E Randolph, 2nd Floor, Chicago
What: Wouldn't it be great to remove the "it works on my machine" scenario? Don't you have better things to do with your time then manually configure systems? In this live, hands-on demonstration Matt will introduce you to the concepts of Infrastructure as Code and Automation; show you how we to use Chef to develop and test system configuration locally, and then deploy them to a production environment in Microsoft Azure. Learn more about Chef on their blog, website, and Twitter!
Who: Matt Stratton is a solutions architect at Chef, where he demonstrates how Chef's automation platform provides speed and flexibility to clients' infrastructure. He is devoted to concepts like Continuous Delivery and Infrastructure as Code, and his license plate actually says "DevOps". He is also a host of the Arrested DevOps (arresteddevops.com) podcast. It's a great podcast, and I am not just saying that because I have been on it :)
Matt has over 15 years experience in IT operations, ranging from large financial institutions such as JPMorganChase and dot coms, including Apartments.com. He has given presentations at Microsoft-sponsored events, CAMP IT, and various local groups within the Chicagoland area.He lives in Chicago and has an unhealthy obsession with Doctor Who, Firefly, and Game of Thrones.
Agenda:6:30pm dinner 7:00pm Presentation
RSVP Now to Attend
Feel free to invite coworkers or friends who would be interested in this talk, just make sure they pre-register! Security requires it, and then I can order the right amount of food. You can park in the Aon center for a discounted rate after 6pm, but your best bet may be SpotHero if you choose to drive. I've seen $10 parking a block away using their service.
ALM | Application Lifecycle Management | Azure | Cloud Computing | DevOps | development | Deployment | Deployment Planning | Continuous deployment | Chef | Continuous Delivery
Angela Dugan is the Polaris Solutions ALM Practice Manager. When she is not wrangling TFS, Angela is an avid board gamer, an aspiring runner (up to 2.5 miles without vomiting!), and a Twitter addict. She lives in a 102 year old house in Oak Park that she is constantly working on with her husband David.
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View Larger Image Lobby Cards 1990's £20-49 Comedy Posters Horror Posters TITLE :"Arachnophobia"Original Set of 8 Lobby Cards / Colour F.O.H. StillsYEAR : 1990 Director : Frank Marshall Cast Info:Jeff Daniels, Harley Jane Kozak, John Goodman, Julian Sands, Stuart Pankin, Brian McNamara, Mark L. Taylor, Henry Jones, Peter Jason, James Handy, Roy Brocksmith, Kathy Kinney CONDITION :A couple of the cards have a tiny indentation spot within the main image area, Otherwise Excellent! Description :Original Set of 8 Lobby Cards / Colour Front Of House Stills (Probably correctly categorised as colour front of house stills as opposed to lobby cards.) Size :10 x 8 Inches / 20 x 25cm approx. Price: £20.00 |
Use the currency converter below as a guide only, the exact exchange rate will be determined by Paypal at chekout. |
Source: ExchangeRates.org.uk |


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Marty MacKay, DMCP, President of HGA, comments, "IMEX America is essential to our industry and I am delighted for HGA to have so much representation at the show featuring our great destinations. We are ready for another successful year with our DMC members and looking forward to connecting with clients and partners."
IMEX America is the perfect opportunity for planners to meet with the HGA Global Sales Team and HGA DMC members from around the globe all in one place, booth #1220. HGA's IMEX appointment diaries are exceptionally busy, and clients are encouraged to book an appointment with their HGA Global Sales Liaison and HGA members soon, as appointment slots are quickly being filled. Click here to make an appointment with a member of the HGA Global Sales Team.
HGA's Exclusive Customer Event on October 18th has become one of the hottest tickets for IMEX afterhours, so much so that the event has moved into the TAO Nightclub. This year promises not to disappoint as HGA will treat guests to the H Factor through remarkable cuisine, delicious beverages, and incredible networking opportunities. HGA, known for their hip hospitality, has added REVO as a sponsor who will be raffling off REVO sunglasses throughout the event. Clients who have RSVP'd for this exclusive event are encouraged to collect their event credentials at the HGA booth (#1220) during exhibiting hours on October 18th. Credentials are sponsored by Totally Mod and are required for entry into the event.
Displaying at the Hosts Global Alliance booth #1220:
HGA Global Sales Team:
Karen Christensen, CMP • Dee Kirby • Cynthia Lavery • Serena Melancon •
Marty MacKay, DMCP
HGA DMC Members:
[email protected] • +39 Events • Actua DMC Costa Rica • Barefoot Holidays DMC St. Lucia • China Star LTD. • CLINK • Cream of The Crop Events • Eventions of Florida • Group Services Inc. Puerto Rico • Hadler DMC • Hosts Chicago • Hosts DC/Hosts Baltimore • Hosts Las Vegas • Hosts New Orleans • Hosts Southern California • Island Partners Hawai'i • JPdL • Key Events • Maple Ridge Events • NXTevent Inc.
HGA prepares for IMEX America 2016 in Las Vegas
- Details
- Category: Show
Hosts Global Alliance (HGA) is preparing for the 2016 IMEX America Tradeshow in Las Vegas, Nevada, taking place from October 18th – 20th at the Sands Expo Center. This worldwide exhibition of incentive travel, meetings, and events is the most widely attended event management tradeshow in North America.


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Kingston Hat
by Hélène Rush
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© Knit One, Crochet Too
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Kingston Hat
by Hélène Rush
This hat can also be worked using Ty-Dy Cotton. It takes one ball each of 2 colors. Very nice for a colorful, slouchy summer hat.
Note: If you've purchased this pattern before 2/18/13, please contact us to obtain an updated version. We've written out the color pattern to make it easier to keep in established pattern :)
For more information, see:
About this pattern
by Hélène Rush
16 projects,
in 9 queues
About this yarn
by Knit One, Crochet Too
100% Wool
218 yards
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AWStats Review
AWStats is a detailed web statistics program that comes combined with many hosting accounts, and has been around for years. While it does not track specific ad performance and revenue, like Google Analytics, it does provide much information on your traffic and keywords. Without doubt, understanding these numbers can help you to identify trends and opportunities, which in turn leads to added profit. The numbers will also tell you whether you have problems with the technical aspects of your website such as broken links and downtime.
Advanced Web Statistics is divided into 18 sections for easy reading. Each domain on a server gets its own stats page and the segments include:
- a summary for the month-to-date
- monthly history
- days of month
- days of week
- hours
- visitors' countries
- hosts (IP addresses)
- robots and spiders who visited
- visitor durations
- file types
- pages visited including entry and exit
- operating systems used by visitors
- browsers used
- organic traffic from search engines
- traffic from other webpages
- search key phrases and keywords
- miscellaneous such as adding favorites as bookmarks
- HTTP status code which are 301 and 302 redirects, 404 not found, and others
Each of these sections show the top ten informational pieces, then if you want further details, you can click on the link to find all the others.
The keyword phrase section is particularly useful because you may be targeting one keyword while getting your traffic from another entirely different keyword phrase. Knowing this information can help you in two ways:
- by helping you focus on keywords of which you were not aware, and expand them, or at least maintain their presence if the traffic volume is high enough, and
- by telling you that you are not making progress with the keywords you targeted in which case you need to modify your promotional efforts.
Further, the section on search engines, when used in conjunction with the spider visits will help you to know which search engines are giving you the most attention. Let's assume you notice that you do not have one visitor that was sent by Google, but you have plenty from Yahoo and Ask Jeeves. The first thing you should do is check to see if the Google bot has come around. If not, then there is a good chance that Google does not even know about your site. This is an opportunity because you know you can increase your traffic by getting into Google's search results.
Another key item is the duration or time a visitor spends on your site. By using this section hand-in-hand with the entry and exit stats, you know whether or not visitors are finding what they need. If they leave seconds later from the page they entered, it might suggest you have nothing to offer them. You do have to be careful here with your analysis because conversely, people might be leaving the page to access the sales form or payment page.
Obviously, by knowing the browser and operating systems of your visitors, you can decide how to enhance your website. It is important that the site be compatible for the bulk of your traffic. So for example, if less than one percent of your users are on some obscure browser, it does not make sense to spend the money upgrading your site. On the other hand, if forty percent are using a browser for which you have not tested your webpages, you better get working on that right away.
Finally the monthly and daily numbers are quite important to you because you want to know if your site's traffic is increasing. Maybe you bought advertising and you want to know if it is at least producing visitors. There should be a direct correlation between the ads and the traffic. Assuming all other things are equal, the week you run an ad should be the week you see more traffic. Plus, monthly stats from past years will indicate trends or patterns of traffic that may be seasonal in nature.


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17 members
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This is a group where all the New and Existing Electric Drive smart owners can get together on sUSAi, to show, discuss and teach everyone what a…
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Company : Atlantic Ultraviolet Corp
UMDC Code : 101065
The MINIPURE design has been carefully conceived to provide adequate germicidal dosage throughout the disinfection chamber. The dosage, as it applies to ultraviolet disinfection, is a function of time and the intensity of ultraviolet radiation to which the water is exposed. The exposure time, in seconds, is the total time it takes the water to flow through the disinfection chamber exposing it to the germicidal lamp. Exposure time is related to the flow rate; the higher the flow rate, the lower the exposure time or the lower the flow rate, the higher the exposure time. The ultraviolet intensity is the amount of energy, per unit time, emitted by the germicidal lamp. The dosage is the product of ultraviolet intensity and the exposure time.
Product URL : http://www.ultraviolet.com/water/minipu01.htm
Last Updated : 11/09/2012
Categories : "Water Purification Systems, Ultraviolet"
Please provide the following information and a representative of Atlantic Ultraviolet Corp will contact you to assist with any questions you might have.
e-NEWSLETTER SUBSCRIPTION
AMD Update is a monthly e-newsletter dedicated to bringing to the ophthalmologist the latest and most useful clinical information and literature reviews on the management of AMD in a quick, easy to review format
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Commercial Solutions
***Clearance*** Epson
Solvent Media
Demo Printers
Photographers whose work includes fine art can choose GALERIE Prestige Smooth Fine Art paper for exceptional quality digital prints. The 100% cotton rag, acid-free textured matt surface offers excellent image stability and like other papers in the Smooth range, has the flexibility of dye and pigment ink compatibility. Prints produced on the 190gsm fast drying paper delight photographers wanting the look and feel of a traditional fine art print


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1. (TCO 1) Which of the following are potential health outcomes of the uninsured?
2. (TCO 2) Which of the following are stakeholders in healthcare policy?
3. (TCO 3) Regressive payments are ____________.
4. (TCO 4) Fee-for-service reimbursement is different than the other units of payment for healthcare. This statement is:
5. (TCO 1) What is a category of underinsurance?
6. (TCO 3) In the 1990s, the push for cost containment changed how physicians and hospitals are paid. The changes:
Question 1 (TCO 2) For the last 25 years, what has been the fundamental conflict between purchasers and the healthcare industry?
Question 2 (TCO 4) List the methods of hospital payment.
Question 3 (TCO 2) Does an HMO promote the regionalized or dispersed model of care? How?
Question 4 (TCO 4) What is the concept of patient cost sharing? Is it a painless form of cost control? For whom?
Question 5 (TCO 3) Why has cost containment become such a focus of the American public? Give examples of current cost containment measures commonly used.


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Hotel Ekant
2N ChailHotels
What's Included
Hotel Details
Hotel options available in the package
Destination | Nights | Hotel and Room | Meals |
Chail | 2 night(s) |
Hotel Ekant
Deluxe Room
Room only |
Sightseeing and Transfers
Other inclusions available in the package
- Including w/drink, daily bed tea, breakfast and lunch or dinner
Select Departure Airport:
Prices shown include two way flights, stay and all taxes
* Prices mentioned are for per person on twin sharing basis (minimum 2 people staying together)
Hotel Overview
Ekant, a resort where Hospitality is a tradition and is striving to provide a homely atmosphere with a panoramic view from all of its 17 well furnished rooms with all the modern amenities : 24 hrs.running hot & cold water,wall to wall carpeting, Color T.v.,Cable Connection, Terrace, Yoga & Meditation, Multicuisine Restaurant, Parking, Room Service.
Hotel Highlights
- Hotel has Free Wifi Zones
Facilities at hotel
- Swimming Pool
- Casino
- Pets Allowed
- Room Service
- Golf
- Bar
- Airport Transfer
- Tennis Courts
- Spa
- Children's Club
- Coffee Shop
- Gym
- Restaurant
- Air Conditioning
- Conference Facility
- Baby Sitting
- Wi-Fi
- Concierge Services
Cancellation Policy
- The package once booked is refundable and cancellable.
- Flight cancellation will be as per airline cancellation policy.
- Date of booking to 30 days before travel the cancellation charges will be 10% of the tour cost
- 30 to 15 days before travel - cancellation charges will be 50% of the tour cost
- 15 to 7 days before travel - cancellation charges will be 75% of the tour cost
- 0 to 7 days before travel - cancellation charges will be 100% of the tour cost. No refund shall be given
- Please note cancellation policy is subject to change. It depends on the hotel policy. In peak season, some hotels may charge 100% cancellation.
Additional Information
- Check-in at hotel starts from 14:00 hrs.
- Check-out time is until 12:00 hrs.
- Early check-in or late check-out is subject to availability and may be chargeable by the hotel.
- Once your payment has been processed, we will send you an email confirmation.
- You will receive all travel vouchers required for your flights and accommodation shortly afterwards.


text: 1874 legend of the birth of the legendary watch Piaget, with good at capturing the charm of time and the pursuit of superb craftsmanship, the watchmakers of the works presented to the world, and make it timeless, in the rolex replica uk sector has an impeccable position The Today, Xiao Bian for everyone to bring the Piaget Polo series watch Pieces of the latest market, I hope you like. ● maintenance recommendations: Automatic mechanical movement recommended every 3 to 5 years to clean up once, leather strap wear when not forced to pull, so as not to hurt the strap, affecting its life. Steel strap wear and do not rub with the swiss replica watches hard objects, so as not to scratch, affecting the appearance of the watch. ● Edit Comment: Piaget Polo series watch is not only the count of a senior rolex replica watches series, it is a mark of the count, a symbol of its brand manufacturing talent. Case, bezel and the perfect combination of strap, the life of art and the perfect fusion of time, anytime, anywhere to show the elegant and charming temperament.


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What began as a prescribed fire Thursday morning in the Cedar Key Scrub State Reserve became a wildfire around noon when unpredictable weather conditions caused fire specialists to lose control, according to Senior Forestry Ranger Jerry Horton.
The wildfire was approximately 150 acres as of 6 p.m., Horton said.
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Refine your search
Welcome to Dalegate Market | Shopping & Cafe, the independent retail site with shops & Deepdale Cafe in Burnham Deepdale. The shopping centre is on the A149 coast road, approximately half way between Hunstanton and Wells-next-the-Sea in the heart of the beautiful North Norfolk Coast. The centre is a major North Norfolk Coast hub, offering a place to relax shop, eat, drink and connect with friends and family.
There's great food and drink from Deepdale Café, offering breakfast, lunch, tea, coffee and cake. The shopping site is home to mainly independent shops - Keshco supermarket & fuel station (petrol & diesel), Fat Face clothing & accessories shop, Gone Crabbing Norfolk clothing & souvenirs shop, Relish jewellery & accessories boutique, One Stop Nature Shop, The Hare & The Hen gallery and Philippa Lee pottery workshop. The shops are joined by Deepdale Bike Hire, Norfolk Hideaways holiday cottage agency and Deepdale Information visitor information centre (TIC).
Dalegate Market welcomes Pop Up Shops a week at a time throughout the summer and at various other times of the year. Dalegate Market is also home to one of the major North Norfolk Coast events - Deepdale Christmas Market.
Dalegate Market is popular with visitors, tourists and locals, whether they are shopping for the essentials like bread and milk, or spoiling themselves or others with presents and gifts such as jewellery, clothing, toys, art and crafts. The site fits well with the tourism facilities of Deepdale Farm next door, which include Deepdale Backpackers Hostel, Deepdale Camping, Deepdale Tipis and Yurts and Deepdale Granary Group Hostel.
Dalegate Market is popular with visitors, tourists and locals, whether they are shopping for the essentials like bread and milk, or spoiling themselves or others with presents and gifts such as jewellery, clothing, art and crafts. Come and join us for some retail therapy for wonderful items that you won't find on the high street.
Opening details
Free entry
Also at this Venue
Events at this Venue
date | event |
Thu 30 Mar | Jacket Thursday @ Deepdale Cafe |
Thu 30 Mar - Tue 4 Apr | Pop Up Shops |
Thu 6 - Tue 11 Apr | Pop Up Shops |
Thu 13 - Tue 18 Apr | Pop Up Shops |
Thu 20 Apr | Jacket Thursday @ Deepdale Cafe |
Thu 20 - Tue 25 Apr | Pop Up Shops |
Dalegate Market
01485 210305
Main Road,
Burnham Deepdale,
On the A149 coast road, approximately half way between Hunstanton and Wells-next-the-Sea, on the beautiful north Norfolk coast
Coasthopper Bus Service
The Coasthopper Bus Service stops at Dalegate Market and is a brilliant service, running approximately every 1/2 an hour during the Summer and every hour during the Winter. The service runs both East and West along the North Norfolk Coast, stopping in most villages including King's Lynn, Hunstanton, Burnham Market, Blakeney, Sheringham and Cromer. More information on the service can be found at www.coasthopper.co.uk
Coach parties are welcome at Dalegate Market, although we would highly recommend booking in advance if you want to eat at Deepdale Cafe, as it can be busy throughout the year. There is good parking for coaches in the layby opposite Dalegate Market. Many coach parties combine a visit to Dalegate Market with St Mary's Church on the opposite side of the coast road and the National Trust owned Brancaster Staithe Harbour. Please see the Group Visits page.
The nearest train station is King's Lynn, which has direct trains from Cambridge and London King's Cross. By changing at Ely and Cambridge you can also catch trains from Stansted Airport, Peterborough and further afield. There is also a station at Sheringham, which has trains to Norwich. The Coasthopper bus service connects with trains at both King's Lynn and Sheringham. Although there are occasional restrictions, you can normally bring your bike on the train.
National Coaches
The nearest national coach station is King's Lynn, which has direct national coaches from Cambridge, Peterborough and London Victoria. The Coasthopper bus service connects with trains at both King's Lynn and Sheringham. If you are cyclist, then trains are the best option, as you can only put folding bikes on national coaches.
Norfolk Coast Path
The Norfolk Coast Path heads both East and West along the North Norfolk Coast and can be accessed down the lane opposite Dalegate Market. The path offers wonderful walking along sea walls, across boardwalks and beaches. You can link up with the Coasthopper at many points along the path. More information on the path can be found at www.nationaltrail.co.uk/peddarsway
Most of the A149 coast road is ok to cycle and there are lots of quiet country lanes inland. From the East (Burnham Market direction), the easiest route is over Whiteway Road. From the West (Docking & King's Lynn direction), the easiest route is down Dalegate Lane. National Cycle Route No1 passes a couple of miles inland. Remember you can hire bikes from Deepdale Bike Hire.
Naturally we'd encourage you to visit by bus, walking or cycling, but car drivers are very welcome too. We offer free car parking and we're one of the few fuel stations (petrol and diesel) along the coast. We're approximately half way between Hunstanton and Wells-next-the-Sea on A149 coast road.
For your satnav our postcode is PE31 8FB - Click here for Google Maps link
Our nearest airport is Norwich. Flybe fly into Norwich from destinations across the UK and Europe, including Paris, Exeter and Edinburgh. KLM fly into Norwich from around the world via Schipol Airport, Amsterdam.
For the major London airports, Stansted, Heathrow, Gatwick and Luton, there are train and national coach services.
: 25 miles from Kings Lynn station
- Baby changing facilities
- Cash Point
- Coach parties accepted
- Credit cards accepted (no fee)
- Disabled access
- Disabled toilets
- Facilities for groups
- Gift shop
- On-site catering
- On-site light refreshments
- Postbox
- Public toilets
- Regional Tourist Board Member
- Telephone (public)
- Accepts groups
- Children welcome
- Disabled access
- Dogs accepted
Self-Assessed Accessibility Details
- Designated parking for shoppers with disabilities
- Within 50 metres approx. of entrance
- Drop-off point for shoppers outside entrance
- Level access (no steps/thresholds) or access by ramp or lift to restaurant / cafe
- Good contrast between the floor and walls
- Seating suitable for wheelchair users, ie moveable and good height for person sitting in a wheelchair
- High chairs for children
- Level access on one floor throughout
- Access to a specially adapted public toilet suitable for wheelchair users
- good contrast between the floor and walls
- Contrast markings on clear surfaces such as glass doors
- Public toilet suitable for wheelchair users
customer loo, public loo at harbour
- Baby changing facilities
- Changing rooms that are accessible for a wheelchair user / carer with children's buggy / person with limited mobility ie with chair
- Low counter at the till for wheelchair users
- Service dogs not accepted:
dogs are welcome in an area of the cafe & outside
- Seating available throughout the facility at appropriate intervals for shoppers with limited mobility
- Contrast markings on clear surfaces such as glass doors
- Routes / aisles throughout the facility suitable for wheelchair users or visitors with limited mobility


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TTF2 Antibody (N-term) Blocking Peptide
Synthetic peptide
Primary Accession | Q9UNY4 |
Clone Names | 81201026 |
Peptide ID | 81201026 |
Gene ID | 8458 |
Other Names | Transcription termination factor 2, 364-, Lodestar homolog, RNA polymerase II termination factor, Transcription release factor 2, F2, HuF2, TTF2 |
Target/Specificity | The synthetic peptide sequence used to generate the antibody AP6813a was selected from the N-term region of human TTF2. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay. |
Format | Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | TTF2 |
Function | DsDNA-dependent ATPase which acts as a transcription termination factor by coupling ATP hydrolysis with removal of RNA polymerase II from the DNA template. May contribute to mitotic transcription repression. May also be involved in pre-mRNA splicing. |
Cellular Location | Cytoplasm. Nucleus. Note=Cytoplasmic during interphase. Relocates to the nucleus as cells enter mitosis |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
firstname.lastname@example.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
TTF2 is a member of the SWI2/SNF2 family of proteins, which play a critical role in altering protein-DNA interactions. This protein has been shown to have dsDNA-dependent ATPase activity and RNA polymerase II termination activity. This protein interacts with cell division cycle 5-like, associates with human splicing complexes, and plays a role in pre-mRNA splicing.
Tonacchera,M., et.al., Thyroid 14 (8), 584-588 (2004)
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text:
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Atari_64 | Date: 8/12/2008 9:58:56 PM ( 9y ago )
Hits: 3816
Context National vaccine recommendations in the United States target an increasing number of vaccine-preventable diseases for reduction, elimination, or eradication.
Objective To compare morbidity and mortality before and after widespread implementation of national vaccine recommendations for 13 vaccine-preventable diseases for which recommendations were in place prior to 2005.
Design, Setting, and Participants For the United States, prevaccine baselines were assessed based on representative historical data from primary sources and were compared to the most recent morbidity (2006) and mortality (2004) data for diphtheria, pertussis, tetanus, poliomyelitis, measles, mumps, rubella (including congenital rubella syndrome), invasive Haemophilus influenzae type b (Hib), acute hepatitis B, hepatitis A, varicella, Streptococcus pneumoniae, and smallpox.
Main Outcome Measures Number of cases, deaths, and hospitalizations for 13 vaccine-preventable diseases. Estimates of the percent reductions from baseline to recent were made without adjustment for factors that could affect vaccine-preventable disease morbidity, mortality, or reporting.
Results A greater than 92% decline in cases and a 99% or greater decline in deaths due to diseases prevented by vaccines recommended before 1980 were shown for diphtheria, mumps, pertussis, and tetanus. Endemic transmission of poliovirus and measles and rubella viruses has been eliminated in the United States; smallpox has been eradicated worldwide. Declines were 80% or greater for cases and deaths of most vaccine-preventable diseases targeted since 1980 including hepatitis A, acute hepatitis B, Hib, and varicella. Declines in cases and deaths of invasive S pneumoniae were 34% and 25%, respectively.
Conclusions The number of cases of most vaccine-preventable diseases is at an all-time low; hospitalizations and deaths have also shown striking decreases.
Author Affiliations: National Center for Immunization and
Respiratory Diseases (NCIRD); Centers for Disease Control and
Prevention, Atlanta, Georgia.
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So, the year is 1973 and the price of gas was going up and people were panicking over a fuel shortage. My parents had the great idea of buying a 1973, brown Camaro with a straight 6, standard transmission and to top it off, No AC!!!
But this story gets better, because in my parents wisdom, they decided to break the car in, we would take a family trip through the US. Shortly after July 4th of 1973, my parents with 2 sisters and myself started out across the country from Louisiana towards Texas. Of course being the boy, I got the pleasure of sitting on a pillow on the hump in the back between my 2 sisters.
From Texas, we went to New Mexico, Arizona (where I got Measles), California, Nevada, Utah, Colorado, Kansas, Missouri, Illinois, Indiana, Ohio, West Virginia, Kentucky, Tennessee, Arkansas and then back to Louisiana.
Let me tell you, that Brown Camaro with no AC got hot and we were always ready for the day to end so we could jump in the nearest pool to cool off. On the other hand, that little Camaro, did get great gas mileage for many years.
Russ J
Jon S
1969 Chevrolet Camaro RS 2dr Convertible
Peggy W
Subscribe to Hagerty's weekly newsletter for stories, videos and news from the classic car world.


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What a great atmosphere and the food to die for . The service was outstanding. This is a great restaurant with fantastic food and magnificent service.
Is this restaurant good for brunch?
Is this restaurant wheelchair accessible?
Is this restaurant good for breakfast?
Is this restaurant good for dining on a budget?
Is this restaurant good for business meetings?
Is this restaurant appropriate for Kids?
Is this restaurant family-friendly?
Is this restaurant good for lunch?
Is this restaurant good for dinner?
Can a vegetarian person get a good meal at this restaurant?
Thanks for helping!
Share another experience before you go.What a great atmosphere and the food to die for . The service was outstanding. This is a great restaurant with fantastic food and magnificent service.
We had a larger party of 6 adults and a baby and got in without any issue. The food took a bit of time to get. The portions are not that grand and prices are a bit high. The service was pretty good. The best thing they had was the pizza. The white pizza was the best part of dinner.... More
The restaurant is in upper east side.In a quiet area.YOu have to travel with a taxi from Midtown city.The price is average, Italian food.It is located in a nice area.
Charged a 20% tip when brought bill because claimed my boyfriend was european and "europeans/foreigners don't pay tip". Charged the suggested tip without allowing us to even decide the tip. Do not go here!! Rude/uneducated manager.
Stumble upon this place while walking around and the kids were hungry for lunch. Hit the spot. Nothing too write home about. Most important..the loved their lunch.
We stumbled upon this restaurant during a visit to the Upper East Side, after the restaurant we intended to go to was packed. The dining room is quaint and cozy with a wood-burning pizza oven nestled in the back. Our waiter was friendly and attentive. We started with wine from the extensive wine list. We shared the glorious eggplant and... More
Outstanding! Had lunch after The Met with my family. Only 3 blocks down tree-lined 80th street is this NYC gem. Our friends highly recommended Tiramisu for their consistently great food. They've been dining there for years and said we had to try for ourselves. We were in the neighborhood, so we did. We had a seat by the front windows,... More
Ambience was decent, their main business appeared to be pizza. My wife and I had fish and veal entrees respectively ,as well as salads. I couldn't get a beer on tap and I had to settle for one of their small selection of bottled beers. Service was good. It was a bit on the pricey side, considering the food was... More
This place is small but the food was good. I didn't love my Western Omelet - it was just ok but the fries were good. My daughters both had pasta and both loved it. It's a small place serving lots of italian dishes with a brick oven for pizza. Small but nice and clean.
very pleasant starter and pasta dish, outdoors in warm autumn weather. service was good and certainly would return for rapid lunch in future
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Colombian and Brazilian jeans designed to lift your feminine curves.
All jeans are exclusive limited editions and designs are not restocked once sold out
Don't Miss These
Enhance Your Curves with Brazilian Jeans
While your wardrobe may be kitted out with well-fitted dresses, nice skirts and comfortable tops, trying to find the ideal pants can be a tough task for many ladies. We have all experienced the difficult task of searching high and low for a pair of jeans that not only look great, but fit comfortably. You walk into a store confident and excited, five pairs of ill-fitted pants later and you leave defeated and angry. Jeans 2 Die 4 present you with a selection of Brazilian buttlift jeans that are tailored to suit many body types as well as remain comfortable and fashionable.
Brazilian and Colombian jeans are designed to enhance your womanly figure with their innovative cut and style. Raising your curves and flattening your stomach, these cleverly crafted pants offer fashion and comfort without any hassles. The waistband design assists in eliminating the dreaded muffin top, while still allowing you the room to breathe. A combination fabric of cotton, polyester and spandex offers a comfortable stretch that simultaneously provides support in all the right areas. The strategic cut and particular stitching of these buttlift jeans help to enhance the curves of anyone looking for that lift and fit!
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Browse the collection of Colombian jeans online and choose from the wide range of colours and styles we have for sale. Manufactured with the curvaceous Colombianos in mind, these creations have in-built body sculpting properties to help you show off your assets. The buttlift style will provide an instant transformation for your body, boosting your comfort and confidence. Options include solid colour Brazilian jean styles, acid wash grey and blue denims and even unique selections with decorative buttons and detailed crystal designs along the ankles and pockets.
Whatever your taste, we offer a range that caters to different styles, shapes and outfits. It doesn't matter if you are naturally curvy or simply want a comfortable design to suit you, there is options for everyone. Browse our online selection and deck out your wardrobe with these amazing Colombianos jeans.


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Smart bra only unhooks for 'true love'
Only "true love" can snap open this high-tech bra. A Japanese lingerie brand boasts its latest product is smart enough to gauge its wearer's real feelings in the heat of the moment — and if it isn't love, then the bra's clasp remains firmly shut. Makers Ravijour explain in a viral video that a hidden sensor in one of the bra's cups is synced via Bluetooth to an app, which measures heart rate. When it hits a certain point — somewhere above shopping, but below jogging, according to a questionably scientific chart — the bra unhooks. "Until now, the bra was a piece of clothing to remove, but now it is an instrument to test for true love," a woman says in the clip. Ravijour is marketing the bra as a way to protect women from unwanted sexual advances. It's not clear how women can unclasp the bra if they don't find "true love." Fans can't buy the bra directly, but win a chance to try it out by spending more than 5,000 Japanese yen (about $50) on the brand's website. |