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Search results for: Army Area Jodhpu
Army Area Jodhpu
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CC's Boutique (Rating: 1) , Votes:With over 30 years of experience CC's Boutique provides brides and bridal parties with the best selection of wedding gowns, bridesmaids' dresses and gowns for Mothers. With two bridal shops in Tampa area, CC's Boutique is convenient to service the entire Tampa Bay area.http://www.tampabridalshops.comCategory: Directory/Shopping/Weddings
My Holiday Home In Lucca - Holiday Villas In Tuscany (Rating: 4) , Votes:The Rental agency is based in the small town of Gallicano in the Garfagnana area, Lucca province - Tuscany - Italy. We offer a selection of holiday properties in the centre of Lucca, in the Garfagnana area (mountains of Lucca province) and in the Versilia (coast of Lucca). Italian, English and German are spoken.http://www.myholidayhome.it
Rezidential Real Estate in Piedmont, Canada (Rating: 4) , Votes:Matt Heafey is a Piedmont real estate agent with knowledge of the Oakland and Piedmont real estate market, which will help any prospective home buyer or home seller in the East Bay Area. The website lists homes in Piedmont, Rockridge, Montclair, Temescal, and Glenview.http://www.mattheafey.comCategory: Directory/North America/Canada
http://www.ufue-hairtransplant.com/ (Rating: 0) , Votes:One of the first fue hair transplants which does need absolute no shaving of hair. Either in the target area nor in the recipient are there is a need for a shaving or to cut the hair. The unshaven FUE Hair Transplant from Doktor Patric Mwamba offering with the "My U-FUE Classic" a hair transplant method without the need of any shaving.http://www.ufue-hairtransplant.comCategory: Directory/Health & Fitness/Beauty
Marquee Hire (Rating: 0) , Votes:Premier Event Marquees provides marquees for hire for events such as weddings and corporate events. The company is based in Yorkshire and has competitive prices for any event and locale within the area.http://www.premiereventmarquees.co.uk/Category: Directory/Shopping/Weddings
Hardwood Floors by Tamalpais - Bay Area and Marin (Rating: 6) , Votes:Tamalpais is a full service hardwood flooring Company providing expert sales and installation of prefinished engineered, solid and floating, as well as bamboo, cork and laminated flooring including eco-friendly floors in the San Francisco Bay area.http://tamalpaishardwoodfloors.comCategory: Directory/Home & Garden/Home Improvement
S.B. Marketing Inc. (Rating: 8) , Votes:We offer Web Design and Online Marketing from Pittsburgh Pennsylvania area. Other services include Graphic Design, Promotional Marketing, and Advertising.http://www.sbmarketinginc.comCategory: Directory/Business/Internet
Select Black Car and Limo (Rating: 0) , Votes:We provide limousine services in the Chicago, IL area. Our services include airport transportation, wedding limo rentals and more.http://www.selectblackcar.com/
OrthoMemphis (Rating: 0) , Votes:We provide integrated physical and occupational therapy with specialized physicians to return patients to an active lifestyle in the Memphis, TN area.http://www.orthomemphis.com/
Cyprus villas (Rating: 6) , Votes:Offer's a unique hand selected holiday villas and holiday apartments in all over Cyprus.http://www.villasrentcyprus.co.ukCategory: Directory/Middle East/Cyprus
Personal Injury Bristol (Rating: 2) , Votes:Expert accident claims advice from personal injury solicitors and lawyers serving the Bristol and Avon area. No win no fee personal injury claims for residents and workers in Bristol. Free consultation available over the telephone.http://www.personalinjurybristol.co.uk/Category: Directory/Business/Law/Attorneys/Lawyers
Houston Apartments (Rating: 7) , Votes:Houston Apartments offers informations about over 1500 apartment communities - photos, prices, and floorplans by submarket, zip code, or school district. In town and suburbs. Search online or get live licensed apartment locator assistance by people who live in the area!http://houstonapartments.comCategory: Directory/Business/Real Estate
The Coolest Bean Bags On The Planet - Bean Bags R Us America (Rating: 3) , Votes:For the Coolest bean bags anywhere online! We carry a large selection of high quality beanbags suitable for indoors, outdoors and the pool!http://www.bean-bags-r-us.comCategory: Directory/Shopping/Home & Garden
Ernst&Haas: Long Beach Property Management (Rating: 8) , Votes:Professional full service property management company specializes in managing rentals throughout the Long Beach area. Includes service listing, available rentals, and contact information.http://www.ErnstandHaas.com/Category: Directory/Business/Real Estate
Simple Search Apartments (Rating: 8) , Votes:Search for apartments in Austin or Houston, Texas using our database. Search Texas apartments by price, area, zip code, school district, pet policy, and amenities.http://www.simplesearchapartments.comCategory: Directory/Business/Real Estate
Dolphin Asset Group (Rating: 0) , Votes:We provide lump sum payouts to customers within the Boca Raton, FL area that are wanting to sell their annuity, structured settlement payment rights, lottery winnings and more.http://www.dolphinassetgroup.com/
Samba Glow (Rating: 0) , Votes:Supplies natural, organic, and paraben free ingredients for spray tans and provides spray tan services to the greater Menlo Park, CA, area.http://sambaglow.com/Category: Directory/Health & Fitness/Beauty
HomeTown Pest Control (Rating: 0) , Votes:Provides home and commercial solutions for termite and pest control problems in the southeastern Virginia area.http://ifitcrawlscall.com/Category: Directory/Home & Garden/Pest Control
Exterior Expressions LLC (Rating: 0) , Votes:Specializes in services including fencing, landscaping, drainage, and decks, for residential and commercial properties. Serves the greater Slidell, LA, area.http://exteriorexpressionsnola.com/Category: Directory/Home & Garden/Gardening
NYC Limo & Car Rental Company - VIP Connection (Rating: 0) , Votes:Provides transportation services including limousines, SUVs, shuttle buses, and sedans to the greater NYC area.http://vipgts.com/Category: Directory/North America/New York
Lisseth Jasso Photography (Rating: 0) , Votes:Offers a wide selection of photography services to consumers within the Houston, TX area.http://www.lissethjasso.com/Category: Directory/Shopping/Photography
Sacramento Movers (Rating: 16) , Votes:Reliable local movers for the Sacramento area including Vacaville, Folsom, El Dorado Hills, and Roseville. Packing, boxes, and relocation services also for long distance moves through Allied.http://www.meemoving.comCategory: Directory/North America/California
Patrick Payroll, LLC (Rating: 0) , Votes:We offer professional full service payroll services in the greater Memphis TN area. We take the pain out of payroll.https://patrickpayroll.com/Category: Directory/Business/Services
Retina Specialists - Retina Associates (Rating: 1) , Votes:Features a wide variety of retina care services to patients in the southern Arizona area.http://retinatucson.com/Category: Directory/North America/Arizona
Revid Property Management (Rating: 0) , Votes:Specializes in property management services including day to day operation, rental homes, and more. Serves the greater Memphis, TN, area.http://www.revidrealty.com/Category: Directory/Business/Real Estate
All Valley Auto Glass (Rating: 0) , Votes:Offers auto glass replacement and repair services to the greater Los Angeles area.http://allvalley-autoglass.com/Category: Directory/North America/California
Lake Amistad Realty (Rating: 0) , Votes:Lake Amistad Realty is located in Del Rio TX and can help buy or sell a home in the area.http://www.lakeamistadrealty.com/Category: Directory/Business/Real Estate
Attorneys & Lawyers (Rating: 4) , Votes:Find attorneys and lawyers in your area, search by location or practice. Also provides law insight articles and legal resources. This website does not offer legal advice.http://www.attorneys.orgCategory: Directory/Business/Law
Jaguar PA (Rating: 2) , Votes:Welcome to Reedman Toll Jaguar. We Serve Langhorne and the Greater Pennsylvania area. We have a full online inventory of new and used Jaguar cars.http://www.reedmantolljaguar.com/index.htmCategory: Directory/Shopping/Automotive
Search Engine Optimization New Zealand (Rating: 11) , Votes:Search Engine Optimisation is important because 55% of all online purchases originate from Search Engines as opposed to only 9% from banners. Truly successful SEO projects require the use of a disciplined approach and proven methodology. First Rate's approach to SEO has taken 9 years to perfect. First Rate is one of the most experienced companies in Australasia in this area.http://www.firstrate.co.nz
Distinctive Outdoor Spaces LLC (Rating: 0) , Votes:Specializes in services including design and construction of landscape and hardscape, lawn care, lawn lighting, and property maintenance. Serves the greater Downingtown, PA, area.http://doslandscaping.com/Category: Directory/Home & Garden/Gardening
Business Analyst Certification - Online Training & Degrees (Rating: 2) , Votes:Business analysts are needed in many businesses to analyze the organization and design of the company and make changes for the better.http://www.businessanalystcertification.orgCategory: Directory/Education/Distance Learning
Chicago Limousine Service (Rating: 2) , Votes:Echo Limousine is providing luxury car services for Illinois, Indiana & Wisconsin area.http://www.echolimousine.com/Category: Directory/North America/Illinois
Reflections Recovery Center (Rating: 0) , Votes:Specializes in long term drug and alcohol rehabilitation and therapy services to the greater Prescott, AZ, area.https://www.reflectionsrecoverycenter.com/Category: Directory/North America/Arizona
Melo Air Inc (Rating: 0) , Votes:Melo Air Inc is a residential and light commercial air conditioning and heating company in Tampa, Florida that specializes in the installation, maintenance and repair of all brands of HVAC equipment. Services is available seven days a week throughout Hillsborough, Pinellas, Pasco and Polk counties.http://www.meloairinc.comCategory: Directory/North America/Florida
Russel Williams Home Services (Rating: 0) , Votes:Offers services including window cleaning, window tinting, holiday lights, and more. Serves the greater Minneapolis, MN, area.http://www.russelwilliams.com/Category: Directory/Home & Garden/Home Improvement
Children's Entertainer in Swindon - Ozzy Wizzpop (Rating: 0) , Votes:Birthday magician for the Swindon area. I offer a complete 2 hour party package with balloon modelling and party games.http://ozzywizzpop.com/wiltshire/childrens-entertainer-swindon/Category: Directory/Arts & Humanities/Performing
Real Property Management Dade (Rating: 0) , Votes:Offers property management services to the greater Miami, FL, area.http://rpmdade.com/Category: Directory/North America/Florida
Alpha Spine and Wellness (Rating: 0) , Votes:Offers chiropractic care to patients in the greater Slidell, LA, area. Services including spinal correction, adjustments, corrective exercises, DME, lifestyle advice, nutritional counseling, massage therapy, and spinal and postural screenings.http://alphaspineandwellness.com/Category: Directory/Health & Fitness/Alternative
Finance Globe (Rating: 0) , Votes:Offers financial tools and resources such as a finance glossary, credit card rates and reviews, calculators, an optional member's area and more.https://www.financeglobe.com/
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Webotopia provides a business directory designed to promote Army Area Jodhpu companies, products and services whilst helping it's users find the Army Area Jodhpu information they need. Webotopia business directory, with the help of it's dedicated support specialists and reviewers, enables delivery of Army Area Jodhpu quality content, excellent customer support as well as value added services such as content publishing and press releases for it's users.


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wikiHow to Create a Character in Lego Star Wars
Tired of playing as players made by the game "Lego Star Wars" (for PlayStation 1, 2, 3, and PSP)? If you are then start reading this article to create 2 characters designed by yourself!
1When you begin the game, you will start as Princess Leia and Captain Antilles in the Star Wars cantina. Go to the Bacta tanks on the right side of the bar.
2Use the up and down arrows to select the part of the character (hat, head, shirt, arms, hands, weapon, belt, and legs) and the left and right arrows to select through a selection of the body part you are on.
3Press "triangle" to name it, and "O" to save and exit.
4Now enter a completed level and turn on free play. Then click on a face that is gray/blackish (around the middle of the character selection). That's your character!
Community Q&A
Ask a Question
200 characters left
If this question (or a similar one) is answered twice in this section, please click here to let us know.
- As you complete levels you unlock more body parts and/or accessories for your customized character.
- Enter BEN917 in the "cheats" section to unlock Ben Kenobi (ghost) for purchase at the price of 1,100,000 Lego studs.
- Try a red lightsaber on your customized characters because only it can take on the Sith's force powers and can move things a Sith can move.
Things You'll Need
- A PSP, and/or a Playstation 2, a Playstation 3, or anything capable of the game "Lego Star Wars"
- The game Lego Star Wars
Article Info
Categories: Lego Star Wars
Thanks to all authors for creating a page that has been read 14,475 times.
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Wednesday, November 13, 2013
making peace with ivf
13 comments:
LOVE THIS! Love, love, love it! So thankful you're willing to tackle the big issues like faith and sin and IVF! I've wrestled with this for so long and I'm coming to grips with the fact that there will still be unanswered questions even when we reach our IVF start date... unless the Lord sends a clear message to answer all my questions, there's just too much gray. : ( Thankful that you have a peace with your decisions and that the Lord has blessed you richly!
ReplyDeleteI really appreciated this post. I am going through similar thoughts and dilemmas since we will most likely be starting IVF after the New Year. I think it's so important to have this kind of dialogue and for women to be able to work out their decisions without judgement or condemnation. I think I probably read the same book you mentioned. I agree that it presented the "black," "white," and "gray" areas. While I appreciated that, I agree with your point about us needing to be clear on what God is calling us individually to do with those gray areas.
ReplyDeleteIt's so interesting to me how different people's faiths can be SO different when it comes to matters like this. I'm a religious person and believe in God, but I'm an ELCA Lutheran (not Catholic, which I'm guessing you are), and my particular division of the Christian Faith has no problem with IVF. I mention this only to say that sometimes it's hard for me to wrap my mind around the fact that in addition to all of the pain people have gone through to get to the point that they have to make a decision of to do or not to do IVF, it's astounding me to me that people of your particular denomination also have to struggle with the decision of whether or not it's a sin to pursue ART. Mind blowing.
This was a really interesting post, and I love your point about needing to decide whether or not each particular grey area is a sin for YOU. Like you said, that can be different for everyone. Priests have to be celibate or it's a sin, but parishioners are meant to procreate and it's not a sin. Hm...
Thanks for sharing...RepliesThanks so much for your comment, Josey! Actually, I'm not Catholic. I grew up Evangelical and now attend a non-denominational church. Our church doesn't have teaching on the use of reproductive technologies. When I mentioned my faith community, I was referring to our friends and family who share our Christianity in general. We've had lots of friends who have pursued IVF and lots of friends who haven't felt completely comfortable with the ethics of it. My personal struggle with the ethics of IVF had more to do with my personal relationship with God than with my religion. I just really felt that it was important to consider all aspects of the process and how they'd impact us and our community in all areas - emotional, mental, financial, relational AND spiritual. Thanks so much for giving me the opportunity to clarify that here! I agree with you though - my heart really goes out to those whose religious leaders have banned certain types of reproductive technologies. Especially those who don't feel that same conviction within themselves.
I love how you put this all into words. While there is not much out there on the subject to research, by you writing this post, it does give others something to at least think about and consider if they are going through the same struggle in trying to decide what is best for them. For me, I have to think that God had a hand in the education of these doctors and the technology that has made ART possible. I spent a lot of time praying about what our next steps in the process should be too. It has to come down to what each person/couple is comfortable doing and can be at peace in their decision. I admire you so much for addressing this topic
ReplyDeleteI have different beliefs than you, but I wanted to thank you for writing this post. This -->
"I think that the ethical/spiritual part of IVF is something that people stray away from for fear of offending people and/or being judged."
<-- is so true, and so very much why the world needs introspective posts like yours. I may not share your beliefs or concerns, but it makes me very happy to read of your own individual decision-making process. It makes us all better people and better members of this community to be exposed to other honest and heartfelt points of view.- AnonymousNovember 16, 2013 at 3:22 AM
Your post brought tears to my eyes as I too have had this back and forth struggle in my heart before my first ivf and it all came back again as now we are pursuing using a donor egg which has brought out even more questions. I too have not found much on the subject and have found that the peace in my heart once I made the decision lets me know that it is the right one. For myself, this journey has required me to find much courage in myself. Thank you for posting on this. It is a relief to know that others wrestle with this spiritually as well. God Bless!
ReplyDelete This is so well written--I love how you articulated it. We're not quite to IVF (or really any treatments yet) because I'm already struggling how to reconcile it with my faith. In some ways, I've convinced myself I'm not pregnant because God doesn't want me to be a mom, so by doing any treatments or even considering adoption, he wouldn't allow it to happen anyway because it's outside of his will (it sounds irrational when I write it, but I'm really struggling internally). Until a few days ago, when the thought was put in my mind, "you take medicine when you're sick, right?" Even though I fully trust that God could heal me on his own, or keep me sick despite the medicine, I still take it. So that's a new thought I'm wrestling with! Thank you for sharing your journey.
ReplyDeleteI love reading this! We are in a place in our journey where were are considering all our options and IVF appears to be so ominous. Thanks you for giving light to it. I appreciate your insight and honesty. None of us thought we'd be walking this road, and it makes it so much easier when the travelers can share their insights with each other. Thanks!!
ReplyDeletesuper interesting read - thank you so much for sharing. love reading others opinions and experience about IVF and alternative methods of conception and "family building".
I'm not religious, but if I were, I think I'd have to subscribe to the thought process that God or whatever being you believe in must have had a hand in creating the doctors, science, and technology that makes this all possible --- and has given it the world, to the people as an option, as a choice, should it make sense in their lives and in their hearts.
It's a fascinating discussion and one I hope others will continue to talk about as I think we all have much to learn! As a donor offspring myself (my parents used an anonymous sperm donor when they faced infertility issues) if find it incredibly personal and insightful. :)


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SAVE THE DATE!! MARK YOUR CALENDARS!! U.S. Army War CollegeClass of 199720th Year REUNION12-15 October 2017Carlisle Barracks, Pennsylvania
The Army War College Foundation & Alumni AffairsPartners in developing the world's foremost strategic leaders.
Our Tribute Program "In Memory Of" and "In Honor Of" is exceptionally personal and professional. We use special cards to notify honorees or family members in a gracious way. We acknowledge tribute gifts in our annual donor report, unless your desire is to remain anonymous. We will gladly tailor notifications to any special circumstances you describe, to include graduations, promotions, etc.
A special characteristic of good leadership is the ability to credit others for their actions and teamwork – symbolizing the best of our military and our nation. Honoring the special people in our lives who sacrificed their blood, sweat, and tears to help us individually and collectively, in protecting our nation's freedoms and opportunities, is not only a tradition but also a privilege.
There is no requirement for the honored individual to be affiliated with the Army War College. There are many people in our lives who should be recognized and they come from all walks of life. We hope you will take advantage of this opportunity to remember and honor a special person in your life, and to help your Foundation support the College at the same time. We are your partner in helping the Army War College produce outstanding senior leaders for today and the future.
The College
The U.S. Army War College is the senior educational institution of the U.S. Army. Among hundreds of distinguished graduates are Generals John J. Pershing, Dwight D. Eisenhower, George S. Patton, Jr., Omar N. Bradley, H. Norman Schwarzkopf, and Admiral William F. Halsey. Click here for a list of U.S. Army War College Commandants.
The Army War College Foundation, Inc. is a publicly supported and IRS designated 501(c)(3) non-profit organization that raises funds and provides other assets to enrich the College's academic programs, research activities, and overall campus environment. Alumni Affairs provides the best possible support to graduates and members.
Located at Carlisle Barracks, Pennsylvania, we enhance the excellence of both faculty and students. Our mission is to assist the Army War College carry out its critical role in the preparation of outstanding strategic leaders.
National Security Seminar


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As those who read my blog will know, I have a very particular attachment to blueberry pie, and every summer, some time during blueberry season, I go to the local farmers market, buy my blueberries, and I bake this particular pie (a layer of whipped cream under a layer of berries)--an offering to the literary muse as well as an offering of gratitude for (and an affirmation of) the friendship I formed with writer Patry Francis, some years ago, in a time before time, via a wonderful no-longer-existing website and on-line forum called Readerville.
Making the pie for my reading group had several benefits: (1) it was a literary event and thus compatible with the literary theme that Patry and I have interwoven with the pie and (2) it brought me an audience of eaters.
Every year, I am very attentive to the making of the pie--how it feels and how I feel and what I can learn from it, about inspiration and concentration and stress and uncertainty--all ingredients in the writing process. This year, to add a new level of immersion, I followed the recipe instructions to look the berries over--discarding leaves and stems and the little green unripe ones and overripe squished ones. I usually conduct this step in the most cursory way, but this year, I looked deeply into the colander, taking the time to sort thoroughly and carefully. How and why this may apply to my current writing project, I cannot say. I only know that I felt compelled to complete this step and that I enjoyed it. Then, as I went, I took a picture of each additional step, emailing it to Patry as I went, thus constructing a photo essay of pie making. I had mixed up the crust (a pate brisee), rolled it out, and frozen it the week before, so forgive me for not including those steps in the essay.
1. The crust lined with foil and filled with rice, ready for the first baking.
2. crust, baked and golden (a little shrinkage, but okay).
3. 1-1/2 cups berries, simmered with sugar and corn starch, butter melting.
4. all berries added, ready for chilling.
5. the whipping of the cream.
6. the spreading of the cream in the crust/
7. Ta-da!


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Published Jun 24, 2016
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Serum activin A and B, and follistatin in critically ill patients with influenza A(H1N1) infection
© Linko et al.; licensee BioMed Central Ltd. 2014
Received: 4 July 2013
Accepted: 2 May 2014
Published: 10 May 2014
Activin A and its binding protein follistatin (FS) are increased in inflammatory disorders and sepsis. Overexpression of activin A in the lung causes similar histopathological changes as acute respiratory distress syndrome (ARDS). ARDS and severe respiratory failure are complications of influenza A(H1N1) infection. Interleukin 6 (IL-6), which in experimental studies increases after activin A release, is known to be related to the severity of H1N1 infection. Our aim was to evaluate the levels of activin A, activin B, FS, IL-6 and IL-10 and their association with the severity of respiratory failure in critically ill H1N1 patients.
A substudy of a prospective, observational cohort of H1N1 patients in Finnish intensive care units (ICU). Clinical information was recorded during ICU treatment, and serum activin A, activin B, FS, IL-6 and IL-10 were measured at admission to ICU and on days 2 and 7.
Blood samples from 29 patients were analysed. At the time of admission to intensive care unit, elevated serum levels above the normal range for respective age group and sex were observed in 44% for activin A, 57% for activin B, and 39% for FS. In 13 of the 29 patients, serial samples at all time points were available and in these the highest activin A, activin B and FS were above the normal range in 85%, 100% and 46% of the patients, respectively. No difference in baseline or highest activin A or activin B was found in patients with or without acute lung injury (ALI) or ARDS (P > 0.05 for all). Peak levels of IL-6 were significantly elevated in ALI/ARDS patients. Peak activin A and activin A/FS were associated with ventilatory support free-days, severity of acute illness and length of ICU stay (P < 0.05 for all).
Higher than normal values of these proteins were common in patients with H1N1 infection but we found no association with the severity of their respiratory failure.
Activin A Activin B Follistatin H1N1 influenza Acute respiratory distress syndrome Interleukin 6Background
Activins are dimeric proteins belonging to the transforming growth factor beta (TGF-β) superfamily. Activin A is involved in many physiological functions including inflammation, tissue remodelling and repair [1–3]. In acute inflammation caused by a lipopolysaccharide (LPS) challenge, serum activin A levels are increased before tumor necrosis factor α (TNFα), interleukin 1β (IL1β) and interleukin 6 (IL6), and stimulate the activin-binding protein, follistatin (FS) which peaks at 3-6 hours post -LPS [4]. Activin has proinflammatory and anti-inflammatory actions [5], and it may modulate the adaptive immune response [6]. Serum activin A is increased in sepsis [7], which is the most common risk factor for acute respiratory distress syndrome (ARDS) [8]. In ARDS patients, activin A levels in bronchoalveolar fluid (BAL) are high, and in mice overexpression of activin A in lungs leads to histopathology resembling human ARDS [9].
Follistatin regulates the activity of activins. Two forms of FS, FS288 and FS315, are products of alternative mRNA splicing. Blocking the action of activin A by FS can halve the mortality of a lethal dose of LPS and highlights the role of activin A in inflammation, leading to therapeutic interest (1). Bleomycin-induced rat lung fibrosis was attenuated [10], and adverse effects of activin A overexpression were decreased by the use of FS in mice [9]. In vivo, blocking activin A enhances adaptive immunity [6].
Influenza A(H1N1) caused a pandemic in year 2009. The majority of H1N1 patients had a mild clinical course, but a minority needed intensive care unit (ICU) treatment for rapidly progressive severe respiratory failure of viral pneumonitis and ARDS [11, 12]. Early treatment with antiviral drugs may improve outcome of severe influenza [13], but no specific treatment for ARDS is available. Severe H1N1 infection is associated with hypercytokinemia [14, 15] and a dysregulated immune response [16]. The increase in IL-6 has been found to correlate with respiratory involvement in adult [17] and paediatric [18] patients. Further, in ARDS caused by other aetiologies, high IL-6 levels have been associated with worse outcomes [19]. Given these results, any potential therapeutic approach that ameliorates this inflammatory response and disease progression requires evaluation.
Accordingly, our study was carried out to assess the pattern of the novel inflammatory regulators, activins and FS, and to compare them with the classic inflammatory mediators IL-6 and IL-10 in critically ill H1N1 patients. Additionally, we evaluated the association of these markers with the severity of acute illness and respiratory failure in these patients.
Patients and study design
This study was a sub-study of the previously published prospective observational cohort study of consecutive, critically ill influenza A(H1N1) patients during the Finnish H1N1 outbreak from 11 October 2009 to 31 December 2009 [20]. All study patients were confirmed H1N1 positive by real-time reverse polymerase chain reaction (PCR) test. The main study consisted of 132 patients from 23 intensive care units. This sub-study was conducted in four ICUs and all 57 patients of these ICUs were considered eligible for the study.
The ethics committee of Helsinki University Central Hospital approved the study. In the main study informed consent was waived for data collection from patient charts. For this laboratory sub-study signed informed consent was required from the patient or next-of-kin prior to blood sample collection.
We recorded patient demographics and clinical data with an internet-based clinical report form provided by the Finnish Intensive Care Quality Consortium (Intensium Ltd, Kuopio, Finland). The collected data has been described in more detail previously [20]. Briefly, co-morbidities, symptom and medication starting times, ventilatory and other therapies, presence of severe sepsis or septic shock and ARDS [21] were recorded. The degree of hypoxemia was evaluated by partial pressure of arterial oxygen divided by the fraction of inspired oxygen (PaO2/FiO2).
Age, gender, Simplified Acute Physiology Score (SAPS) II, Sequential Organ Failure Assessment (SOFA) score components, hospital and ICU admission/discharge times, and ICU and hospital mortality were acquired from the routinely collected benchmarking data (Intensium Ltd, Kuopio, Finland).
The blood samples were collected as soon as possible after ICU admission (baseline), and on days 2 and 7. The serum samples were stored at -20°C during the study period, and then transferred and stored at -70°C until analyzed. Serum activin A, activin B, and total FS were determined using specific ELISAs for activin A and B and by radioimmunoassay for follistatin [22–24]. The intra-assay CV for activin A, activin B and FS were 5.7%, 2.7-6.2%, and 5.8%, respectively. The lower levels of detections were as follows: activin A 7.7 pg/mL, activin B 19.0 pg/mL and FS 1.44 ng/mL. Details of the published defined age-related reference values of 138 healthy persons were used for comparison (de Kretser et al. 2013) (Additional file 1). We calculated activin A:FS-ratio (activin A/FS) as an indicator of available activin A activity.
IL-6 levels in serum were measured by a specific human IL-6 ELISA kit BD Biosciences, San Diego, CA using a human recombinant IL-6 preparation supplied with the kit. IL-10 serum levels were also measured using a specific IL-10 ELISA kit, BD Biosciences, San Diego using a human recombinant IL-10 provided with the kit.
Statistical analysis
Data are presented as median with interquartile range (IQR) or absolute values and percentages as appropriate. We compared the non-parametric data of independent groups using two-tailed Mann–Whitney test and those of several groups using Kruskal-Wallis test. Repeated measurements were compared with Friedman's test. Due to non-normality of activin A, activin B, and FS, Spearman's correlation coefficient (r) was used to test relationships. We used SPSS 19 (IBM SPSS Inc, Chicago, IL, USA and GraphPad 6 (GraphPad Software, LaJolla, CA, USA) for statistical analysis.
Characteristics of study patients compared to other patients
Included H1N1 patients n = 29 | Other H1N1 patients ICUs n = 28 | P value | |
Age, years | 47 [39–56] | 49 [37–55] | 0.994 |
Gender, male | 20 (69%) | 17 (61%) | 0.514 |
Obstructive pulmonary disease | 9 (31%) | 8 (29%) | 0.839 |
Chronic cardiac insufficiency | 9 (31%) | 4 (14%) | 0.207 |
Ischemic cardiac disease | 9 (31%) | 0 | 1.000 |
Body mass index >35 kg/m2 | 11 (39%) | 4 (15%) | 0.070 |
SAPS II, points | 24 [20-32] | 29 [24–39] | 0.016 |
SOFA at 24 h, score | 3 [2-7] | 6 [3–8] | 0.042 |
SOFA maximum, score | 7 [3–9] | 6 [4–11] | 0.493 |
Time from symptoms to hospital admission, hours | 132 [54–188] | 72 [36–168] | 0.115 |
Time from hospital admission to ICU admission | 19 [12–33] | 19 [8–35] | 0.792 |
CRP (mg/L) at ICU admission | 73 [33–163] | 57 [26–199] | 0.965 |
PaO2/FiO2 (mmHg) at ICU admission | 135 [101–261] | 132 [110–299] | 0.492 |
PaO2/FiO2 (mmHg), lowest | 100 [76–134] | 111 [79–269] | 0.274 |
Number of infiltrated quadrants on X-ray at admission | 4 [2–4] | 2 [1–3] | 0.025 |
ALI or ARDS | 19 (66%) | 16 (57%) | 0.516 |
Corticosteroid treatment | 19 (66%) | 13 (46%) | 0.2923 |
Ventilatory support | 0.144 | ||
No | 3 (10%) | 6 (21%) | |
Non-invasive | 13 (45%) | 6 (21%) | |
Invasive | 13 (45%) | 16 (57%) | |
CPAP or PEEP (mmHg) at admission | 7 [5–12] | 7 [6–8] | 0.485 |
Length of ventilatory support, days | 4 [2–10] | 4 [0–9] | 0.485 |
ICU length of stay, days | 5 [2–10] | 3 [1–9] | 0.389 |
Hospital length of stay, days | 12 [7–16] | 11 [5–25] | 0.812 |
ICU mortality | 1 (83%) | 0 | 1.000 |
Hospital mortality | 1 (3%) | 2 (7%) | 0.611 |
Of all study patients, serum activin A levels exceeded the upper level of the normal range in 44% of patients at admission (day 1), in 57% on day 2 and 69% on day 7. For serum activin B levels those exceeding the upper limit were 57% on day 1, 76% on day 2 and 54% on day 7. For serum follistatin, those patients exceeding the upper limit of normal were 39% at day 1, 36% on day 2 and 15% at day 7.
Median [IQR] of highest values was 0.110 [0.085-0.168] ng/mL for activin A, 0.122 [0.078-0.155] for activin B, 12.21 [8.90-19.57] for FS. As normal ranges for the IL-6 and IL-10 assays were not available, the data for these cytokines are provided as the IQR for day 1, day 2 and day 7 and for IL-6 on day 1, day 2 and day 7. The IQR for the highest levels of IL6 was 122.91 [54.60-294.55] pg/mL and for IL-10 28.94 [17.78-49.31] pg/mL. On day two IL-6 correlated with activin A (r = 0.664; P = 0.001) and activin B (r = 0.438; P = 0.028) and activin A/FS (r = 0.477; P = 0.016). Day two IL-10 correlated with the respective activin B levels (r = 0.405, P = 0.045). Highest IL-6 correlated with highest activin A (r = 0.599; P = 0.001) and activin A/FS and (r = 0.590; P = .001).
Association of baseline activin A, activin B and activin A/follistatin with severity of respiratory failure
Activin A | Activin B | Activin A/follistatin | ||
PaO2/FiO2 at ICU admission | D0 | r = -0.093; P = 0.659 | r = -0.073; P = 0.730 | r = -0.023; P = 0.914 |
highest | r = -0.181; P = 0.385 | r = 0.124; P = 0.556 | r = -0.132; P = 0.529 | |
PaO2/FiO2 lowest during ICU stay | D0 | r = 0.122; P = 0.538 | r = 0.186; P = 0.343 | r = 0.105; P = 0.596 |
highest | r = -1.31; P = 0.498 | r = 0.052; P = 0.719 | r = -0.117; P = 0.547 | |
PEEP at admission | D0 | r = -0.071; P = 0.773 | r = -0.093; P = 0.706 | r = -0.039; P = 0.875 |
highest | r = 0.297; P = 0.217 | r = 0.118; P = 0.629 | r = 0.102; P = 0.678 | |
Ventilatory support free days | D0 | r = -0.143; P = 0.467 | r = 0.100; P = 0.613 | r = -0.068; P = 0.729 |
highest | r = -0.452; P = 0.014 | r = -0.166; P = 0.391 | r = -0.446.; P = 0.015 | |
SOFA score, at 24 hours | D0 | r = 0.351; P = 0.067 | r = 0.047; P = 0.814 | r = 0.222; P = 0.257 |
highest | r = 0.466; P = 0.011 | r = -0.095; P = 0.624 | r = 0.369; P = 0.049 | |
SAPSII score | D0 | r = 0.252; P = 0.196 | r = -0.020; P = 0.921 | r = 0.191; P = 0.330 |
highest | r = 0.434; P = 0.019 | r = -0.065; P = 0.739 | r = 0.471; P = 0.010 | |
C-reactive protein at ICU admission | D0 | r = 0.131; P = 0.516 | r = 0.140; P = 0.485 | r = 0.057; P = 0.778 |
highest | r = 0.232; P = 0.235 | r = 0.279; P = 0151 | r = 0.201; P = 0.305 | |
Length of ICU stay | D0 | r = 0.202; P = 0.303 | r = -0.077; P = 0.698 | r = 0.093; P = 0.638 |
highest | r = 0.422; P = 0.023 | r = -0.128; P = 0.507 | r = 0.409; P = 0.028 |
The highest activin A and activin A/FS were associated with less ventilator free days, higher acute disease severity and longer length of stay in ICU, but not with admission PEEP (Table 2). Peak IL-6 and IL-10 were associated with higher admission levels of PEEP (P < 0.05), less ventilator free days, higher acute disease severity and longer stays in ICU.
This study is the first report of elevated serum levels of activin A, activin B and FS in critically ill patients with H1N1 infection. In serial measurements activin A, activin A/FS increased, FS and IL-10 decreased, and IL-6 remained at the admission level during the first week of ICU treatment.
Increase of activin A and FS is in accordance with previous findings in an LPS induced experimental sepsis model [1] and in septic patients [7]. In septic patients, as in the patients in our study, the levels of serum activin A tended to be elevated for days. This finding differed from the rapid peak (1 hour) and return to basal level (5 hours) after experimental LPS injection [5]. In the LPS-induced sepsis model, the higher serum level of activin A was associated with a fatal outcome [1], but not in a small study of septic patients [7]. The small sample size and low mortality in our study prevented any mortality analysis.
To our knowledge, activin B levels have not been reported in critically ill patients. This study showed elevated activin B levels in most of the patients, but the trend was different compared to activin A, suggesting different regulatory mechanisms. In part this is reflected in the acute response to LPS since the activin A response is rapid and does not require new protein synthesis whereas the activin B response is delayed and dependent on new protein synthesis (Hedger et al. unpublished data). This novel finding indicates the need for further studies to delineate the role of activin B in inflammation and fibrosis. To date, activin B, with an amino acid sequence homology to activin A of 65% has been considered as a less potent member of this family of proteins as it was only partially able to compensate for the absence of activin A in a mice with deletion of the activin A subunit [25].
In animal models, FS peaks (4 hours) after activin A and stays elevated longer (24 hours). This pattern arises from the capacity of activin A to stimulate FS production [1]. As the trend of activin A was increasing during the first 7 days, the trend of FS was decreasing. The increasing activin A/FS, an indicator of available activin activity, may implicate dysregulation of activin A and a consequent lung injury. Strong expression of activin A has been found on alveolar macrophages in diffuse alveolar damage, lung fibrosis, and in pulmonary arteries in pulmonary hypertension [2], all of which findings may be present in ARDS. Furthermore, the rapid increase in lung activin concentrations in mice given LPS has been shown to be due in part to the rapid movement of neutrophils into the lungs and the presence of activin A in their secretory granules [26]. Furthermore, TNFα has the capacity to release activin A from neutrophil secretory granules [27]. Recently, Apostolou and colleagues demonstrated that histopathology in ARDS was associated with overexpression of activin A in mice lungs and, additionally, activin A was elevated in BAL fluid in ARDS patients [9].
Of note, contrary to expectations, we found no association between circulating activin A, FS or activin A/FS and ALI/ARDS. There may be several explanations for this result. First, the evidence of parallel circulating activin A and expression in lungs and/or BAL fluid in patients is still lacking. The degree of oxygenation failure in our patients was severe and, thus, obtaining BAL samples, unnecessary to patient treatment, was not justified. Second, compared to animal studies, patient cohorts are more heterogeneous. Although, in this study, all patients were confirmed to have the same infection, other standardization was not possible and different co-morbid conditions, obesity, and septic bacterial secondary infections were present. Third, time from the start of symptoms to hospitalisation and ICU treatment was relatively short, and thus, prompt treatment with oseltamivir and antibiotics may have influenced disease severity and outcome. In addition, the more severely ill patients were more likely to have been treated with corticosteroids [28]. Corticosteroids suppress systemic inflammation in ARDS patients [29], and together with a neuraminidase inhibitor may attenuate tissue damage during experimental influenza infection [30]. Further, administration of glucocorticoids also suppresses activin A expression [31, 32]. Mechanical ventilation [33], prone position [34], and neuromuscular blocking agents [35] all may affect the inflammatory response. Finally, although we analyzed all available samples from cohort of patients with H1N1, due to required informed consent, the patients were not consecutive and the sample size was relatively small. This may have caused a type II error in detecting existing differences in activin and FS levels with regard to disease severity.
In accordance with the previous studies in ARDS [19], we found higher IL-6 in ALI/ARDS patients. Our results also corroborate with previous studies showing an IL-6 increase with respiratory severity in H1N1 influenza [14, 15, 17, 18]. Interestingly, the evolution of IL-6, IL-10 and activin A were different over time. Activin A, activin B and activin A/FS correlated with IL-6 only on day two.
The importance of measuring activin A and B in critically ill patients was illustrated by our previous study of patients in ICU with acute respiratory failure [36]. That study established that patients with both serum activin A and B above the normal range had the highest mortality levels. This outcome may be associated with the capacity of increased levels of activin A to cause apoptosis of hepatocytes and B lymphocytes and to cause the production of nitric oxide (reviewed in [37]). Further exploration of the capacity of soluble activin receptor blockers and follistatin as agents capable of regulating the bioactivity of the activins and their possible role in the treatment of such patients may be of value in the future.
To our knowledge, this is the first study to report increased levels of activin A, activin B and FS, compared to normal range, and simultaneous IL-levels in severe H1N1 influenza. Regrettably, the inclusion of only critically ill patients prevented evaluation of potential association between these inflammatory markers and disease severity, which needs to be scrutinized in a larger population of critically ill patients.
This study establishes that in critically ill patients with severe H1N1 Influenza, the levels of activins A, B and follistatin are elevated in a significant proportion of patients. However, the magnitude of the increase did not correlate with the severity of the infection and the degree of respiratory failure.
Intensive care unit
Acute lung injury
Acute respiratory distress syndrome
- activin A/FS activin A:
Interleukin 6
Interleukin 10
- PaO2/FiO2:
Partial pressure of oxygen divided by the fraction of inspired oxygen
Positive end-expiratory pressure
Of stay
Sequential organ failure assessment
Simplified acute physiology score.
This work has been supported by Grants (to MPH and DdeK) from the National Health and Medical Research Council of Australia, and by the Victorian Government's Operational Infrastructure Support Program.
We thank Oxford Brookes University for kindly supplying reagents used in the activin assays described herein.
We thank all doctors and nurses in the participating ICUs. We greatly appreciate research coordinator Sari Sutinen for the skilful assistance with the blood samples. We also thank the Finnish H1N1 study group.
The Finnish H1N1 study group: participating hospitals and study investigators
Satakunta Central Hospital, Dr. Vesa Lund; East Savo Central Hospital, Dr. Markku Suvela; Central Finland Central Hospital, Dr. Raili Laru-Sompa; South Savo Central Hospital, Dr. Heikki Laine; North Karelia Central Hospital, Dr. Matti Reinikainen; Seinäjoki Central Hospital, Dr. Kari Saarinen; South Karelia Central Hospital, Dr. Seppo Hovilehto; Päijät-Häme Central Hospital, Dr. Pekka Loisa; Vaasa Central Hospital, Dr. Raku Hautamäki; Kanta-Häme Central Hospital, Dr. Ari Alaspää; Lappi Central Hospital, Dr. Outi Kiviniemi; Keski-Pohjanmaa Central Hospital, Dr. Tadeusz Kaminski; Kymenlaakso Central Hospital, Dr. Seija Alila, Dr. Jussi Pentti; Helsinki University Hospital, Jorvi, Peijas and Meilahti Hospitals, Dr. Tero Varpula, Dr. Anne Kuitunen, Dt. Tuomas Oksanen, Dr. Timo Suonsyrjä; Turku University Hospital, Dr. Juha Perttilä; Tampere University Hospital, Dr. Sari Karlsson, Dr. Jyrki Tenhunen; Länsi-Pohja's Central Hospital, Dr. Jorma Heikkinen; Kuopio University Hospital, Dr. Esko Ruokonen, Ilkka Parviainen; Oulu University Hospital, Dr. Tero Ala-Kokko, Dr. Jouko Laurila; Turku University Hospital, Paediatric ICU, Dr. Janne Kataja; Helsinki University Hospital, ICU of Hospital for Children and Adolescents, Dr. Paula Rautiainen.
Key messages
- Activin A and B levels were elevated in most of the H1N1 patients
- The baseline levels of Activin A and B did not correlate with the severity of respiratory symptoms in critically ill influenza A(H1N1) patients, but highest activin A and activin A/FS levels correlated with less ventilator free days, increased acute disease severity and increased ICU LOS
- Future studies are justified to explore the role of acitivins and follistatin in ARDS.
Authors' Affiliations
- Jones KL, Mansell A, Patella S, Scott BJ, Hedger MP, de Kretser DM, Phillips DJ: Activin A is a critical component of the inflammatory response, and its binding protein, follistatin, reduces mortality in endotoxemia. Proc Natl Acad Sci U S A. 2007, 104: 16239-16244. 10.1073/pnas.0705971104.View ArticlePubMedPubMed CentralGoogle Scholar
- Matsuse T, Ikegami A, Ohga E, Hosoi T, Oka T, Kida K, Fukayama M, Inoue S, Nagase T, Ouchi Y, Fukuchi Y: Expression of immunoreactive activin A protein in remodeling lesions associated with interstitial pulmonary fibrosis. Am J Pathol. 1996, 148: 707-713.PubMedPubMed CentralGoogle Scholar
- Hübner G, Hu Q, Smola H, Werner S: Strong induction of activin expression after injury suggests an important role of activin in wound repair. Dev Biol. 1996, 173: 490-498. 10.1006/dbio.1996.0042.View ArticlePubMedGoogle Scholar
- Jones KL, de Kretser DM, Clarke IJ, Scheerlinck J-PY, Phillips DJ: Characterisation of the rapid release of activin A following acute lipopolysaccharide challenge in the ewe. J Endocrinol. 2004, 182: 69-80. 10.1677/joe.0.1820069.View ArticlePubMedGoogle Scholar
- Jones KL, Brauman JN, Groome NP, de Kretser DM, Phillips DJ: Activin A release into the circulation is an early event in systemic inflammation and precedes the release of follistatin. Endocrinology. 2000, 141: 1905-1908. 10.1210/endo.141.5.7531.View ArticlePubMedGoogle Scholar
- Robson NC, Wei H, McAlpine T, Kirkpatrick N, Cebon J, Maraskovsky E: Activin-A attenuates several human natural killer cell functions. Blood. 2009, 113: 3218-3225. 10.1182/blood-2008-07-166926.View ArticlePubMedGoogle Scholar
- Michel U, Ebert S, Phillips D, Nau R: Serum concentrations of activin and follistatin are elevated and run in parallel in patients with septicemia. Eur J Endocrinol. 2003, 148: 559-564. 10.1530/eje.0.1480559.View ArticlePubMedGoogle Scholar
- Ware LB, Matthay MA: The acute respiratory distress syndrome. N Engl J Med. 2000, 342: 1334-1349. 10.1056/NEJM200005043421806.View ArticlePubMedGoogle Scholar
- Apostolou E, Stavropoulos A, Sountoulidis A, Xirakia C, Giaglis S, Protopapadakis E, Ritis K, Mentzelopoulos S, Pasternack A, Foster M, Ritvos O, Tzelepis GE, Andreakos E, Sideras P: Activin-A overexpression in the murine lung causes pathology that simulates acute respiratory distress syndrome. Am J Respir Crit Care Med. 2012, 185: 382-391. 10.1164/rccm.201105-0784OC.View ArticlePubMedGoogle Scholar
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- The pre-publication history for this paper can be accessed here:http://www.biomedcentral.com/1471-2334/14/253/prepub
Pre-publication history
This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited.


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Friday, April 8, 2011
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Udaipur to Mount Abu - Bus Fare & Timings
- Bus-operator From To Cheapest Fare
- Paras Travels Udaipur Mount Abu Rs.250 Paras Travels operates 2 buses from Udaipur to Mount Abu with starting price of Rs.250. First bus starts at 08:30 AM and last bus at 03:30 PM.
- Taldar Travels Udaipur Mount Abu Rs.280 Taldar Travels operates 2 buses from Udaipur to Mount Abu with starting price of Rs.280. First bus starts at 08:29 AM and last bus at 03:29 PM.
- Rishabh Travels Udaipur Mount Abu Rs.335 Rishabh Travels operates 1 bus from Udaipur to Mount Abu with starting price of Rs.335. First bus starts at 08:30 AM and last bus at 08:30 AM.
Udaipur to Mount Abu Bus Services
There are 2 bus operator(s) providing bus service from Udaipur to Mount Abu. The top bus operator(s) for Udaipur to Mount Abu route is Paras Travels. The first bus from Udaipur departs at 08:30 AM and is operated by Paras Travels and the last bus departs at 08:15 PM and is operated by RSRTC. The minimum fare from Udaipur to Mount Abu Bus is Rs. 200.00/- departing at 08:30 AM. One can also avail of Volvo AC, Volvo AC Sleeper, AC Sleeper, AC Seater, Non AC Sleeper, Non AC Seater on this route. The bus(es) usually take a maximum of 9 hours to complete the journey. The most preferred pickup points for Udaipur to Mount Abu buses are Head office paras travels, Bansi pan, Delhi gate.
About Udaipur
Udaipur is a prominent tourist destination in Rajasthan and is called as the "City of Lakes". It is located 403kms from state capital Jaipur. Udaipur is often referred as "Venice of the East". The city is famed with magnificent forts, lakes, palaces and wildlife sanctuaries. Besides having rich heritage, Udaipur is also known for its rich culture and tradition that can be witnessed during festival period. As mentioned, Udaipur is famous for its lakes; there are few that are worth exploring like: Fateh Sagar, Pichola Lake, Jaisamand Lake and Udaisagar Lake. Each lake has its own distinct features making it the top tourist locations. Udaipur is the major royal wedding destination in India, which takes place in palaces and hotels. Some of the major attractions in Udaipur are: Kumbhalgarh Fort, Lake Pichhola, City Palace of Udaipur, Jag Mandir, Cable Car, Vintage Collection of Classic Cars Museum and other locations. If you love exploring palaces and rich culture, Udaipur is a city to visit.


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In the San Jose, CA market in May, new home closings dropped year-over-year, and there were hints of worsening market conditions as the percentage fall was steeper than April 2016. New home closings saw a drop of 31.5% from the year earlier to 102. This followed a 24.0% drop year-over-year in April.
A total of 2,060 new homes were sold during the 12 months that ended in May, down from 2,107 for the year that ended in April.
As a percentage of overall housing closings, new home closings represented 6.2%. This is down from the a year earlier when new home closings accounted for 8.4% of total closings. For new and existing homes, closings dropped in May after also declining in April year-over-year.
Pricing and Mortgage Trends
For newly sold homes, the average price moved from $883,067 in May 2015 to $880,721 in May 2016. This came after a 3.8% decline in April from a year earlier.
The average mortgage size on newly sold homes saw a hike year-over-year in contrast to new home prices. In May 2016, the average mortgage size on newly sold homes saw a 6.5% boost from a year earlier. It went from $634,548 to $628,717 from April 2015 to April 2016.
Other Market Trends
Single-family homes accounted for a greater percentage of new home closings than last year. Single-family home closings increased from 37.6% of new closings in May 2015 to 53.9% of closings in May 2016. At the same time, the share of new home closings belonging to attached units declined to 46.1% of closings from 62.4% of closings.
There was a 20.5% fall year-over-year in the average unit size of newly sold homes to 1,459 square feet in May 2016. The average size of newly sold homes moved from 1,943 square feet in April 2015 to 1,634 square feet in April 2016.
Foreclosures and real estate owned (REO) closings continued to decline from a year earlier in May, but did not look to be a burden on the market. Out of all existing home closings, foreclosures combined with REO closings made up 3.8% of closings, below 4.4% a year earlier. The percentage of existing home closings involving foreclosures went from 2.0% in May 2015 to 1.6% in May 2016 and REO closings moved from 2.3% of existing home closings in May 2015 to 2.2% in May 2016.
Please refer to the ABOUT THIS MSA tab to learn more about geographic coverage and data availability in the San Jose, CA area.


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The Moong dal recipe I am going to teach you today, is a simple dry dish you can make in 5 minutes. This is a south Indian style dish wherein we will cook the moong dal, fry it with dry red chilli and mustard seeds and urad daal.
This recipe is something that you can have for a quick snack or to complement your lunch.
Let me show you how to prepare this recipe.
1. Take ½ cup of moong daal and wash it well. In a pressure cooker pour 2 glasses of water and cook the daal for 2-3 whistles.
2. Check if the daal is cooked. If so, heat oil in a pan.
3. To this add ½ tbsp. mustard seeds, ½ tbsp. of urad daal, 2 dry red chilies, 1 green chilly, and 3-4 curry leaves.
4. Add the cooked daal into the pan and stir it well. Pour 1-2 tbsp of coconut oil and ¼ tbsp. of hinge on top the mix and stir well.
5. Garnish with some curry leaves and switch off the flame. Your moong dal fry is ready.
Moong dal recipe tastes better when you add fresh coconut gratings on top of it while frying. | |
It is an excellent dish to have with rice porridge. | |
Ensure that the moong dal doesn't gets over cooked. It is better to keep it to 2-3 whistles in the cooker. |


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United States, Brooklyn, NY, USA -
Architect in Charge
Leeser Architecture -
47000.0 ft2 -
Project Year
Coworkrs / Leeser Architecture
WXY Releases Plans for 50 Acre Public Space Stretch in Brooklyn
Design firm WXY architecture + urban design has released plans for a reconnection of nearly 50 acres of public space between downtown Brooklyn and the Brooklyn Bridge in New York. Called The Brooklyn Strand, the project seeks to create a more appealing and accessible waterfront, while transforming the quality of public space in the area.
Louis Kahn's Roosevelt Island Memorial in the Firing Line Over Accessibility Dispute
Throughout the four years since the opening of the Franklin D. Roosevelt Four Freedoms Park on Roosevelt Island, New York City Hall has been arguing with the nonprofit group, the Four Freedoms Park Conservancy, over whether the park is adequately accessible to disabled people, reports The New York Times.
The park was designed from 1972 to 1974—before the advent of the American With Disabilities Act of 1990—by architect Louis Kahn, who died in Pennsylvania Station carrying the plans for the finished memorial. At its southernmost end the park features a 12-by-60-foot sunken terrace that, ironically, President Roosevelt himself would not have been able to use with his wheelchair.
New York 2030: This Annotated Visualization Shows Us the Manhattan of the Future
Fourteen years from now, New York's skyline will be one vastly different than the recognizable profile visible today. With dozens of new projects set to make their mark on the city, the creative design company Visualhouse - specializing in 3D visualizations - has released a rendering of New York in 2030. "This image shows the who's who of modern architecture - with buildings designed by Jean Nouvel, Rafael Vinoly, Bjarke Ingels Group, SOM, Foster + Partners, and Kohn Pedersen Fox, just to name a few," said Visualhouse CEO and Founder, Rob Herrick. "How these modern day masterpieces all fit together in the sky space, that will be the legacy for New Yorkers in 2030 and beyond."
Manus x Machina / OMA
Metropolitan Museum of Art, New York, NY 10028, United States -
Partner in Charge
Shohei Shigematsu -
The Costume Institute at the Metropolitan Museum of Art -
18300.0 ft2 -
Project Year
2016 -
The Jane Jacobs Documentary to Premiere Fall 2016
The Jane Jacobs Documentary - a feature length film focusing on the life and work of celebrated author and urban activist, Jane Jacobs - is set to be released Fall 2016. Coinciding with the author's 100th birthday, Robert Hammond, Co-Founder and Executive Director of Friends of the High Line, and Matt Tyrnauer, producer/director of Valentino: The Last Emperor, plan to have the film tour festivals near the end of this year.
New York's 1851 Landmark, the Serbian Orthodox Cathedral of St. Sava, Burns in Fire
The Serbian Orthodox Cathedral of St. Sava, a New York landmark built in 1851 by Richard Upjohn, burned Sunday night in a fire after more than 700 parishioners celebrated Easter, reports NBC New York. Originally known as Trinity Chapel, the cathedral was created as satellite location for Trinity Church at Wall Street and Broadway in Lower Manhattan, also designed by Upjohn, after parishioners began to settle farther from the original location. The church was later joined by a Clergy House and the Trinity Chapel School in an ecclesiastical complex, but in 1943 the chapel and neighbors were sold to the Serbian Orthodox Church. The cathedral, stretching between 25th and 26th Street, was nearly 180 feet long, and had one of the largest hammerbeam roofs in the city. The New York Landmarks Conservancy partnered with the church for a 2002-03 restoration of the building's facade and roof. The four-alarm fire that was contained by Monday morning is under investigation as suspicious.
Gallery: Santiago Calatrava's WTC Transportation Hub Photographed by Laurian Ghinitoiu
Since it opened to the public two months ago, Santiago Calatrava's World Trade Center Transportation Hub has been the subject of intense debate. Critics and the public alike have tried to answer whether the building, while undeniably unique and striking, was worth the $4 billion price tag that made it the world's most expensive train station. Key to this question's answer will be the way that the building settles into its role as a piece of the city's fabric.
With construction work still surrounding the building - both on the site itself and at the nearby skyscrapers - photographer Laurian Ghinitoiu turned his camera lens onto the station to see how it has been absorbed into the life of the city, capturing the way the structure is revealed from unexpected vantage points and showing how its users react to the sublime internal space of the "oculus."
Novogratz Center for Athletics / Jack L. Gordon Architects
Dyker Heights, Brooklyn, NY, USA -
27900.0 ft2 -
Project Year
2016 -
SHoP Unveils Design for New Skyscraper in Manhattan's Lower East Side
SHoP has unveiled the design for a new 900 foot tall skyscraper in Manhattan's Lower East Side. The 77 story, 500,000 square foot, mixed-income tower will have 600 units, 150 of which will be permanently affordable and distributed evenly throughout the building. The project has been developed as a collaboration between SHoP and JDS who are co-owners of the development, with the partnership of two not-for-profit groups: Two Bridges Neighborhood Council (TBNC) and Settlement Housing Fund (SHF).
Lisson Gallery New York by studioMDA and Studio Christian Wassmann Opening Soon Beneath the High Line
On May 3, Lisson Gallery New York will open beneath the High Line between 23rd and 24th Street. Designed by studioMDA and Studio Christian Wassmann, the 8,500 square foot space is split between a gallery, offices, viewing rooms, and storage. Although the main gallery is directly under the High Line – the steel columns in the photos are actually supports for the elevated railway – it will receive ample sun from dramatically angled skylights along the space's edge, which also aid to extend the walls vertically. The gallery's polished concrete floors, white walls, and natural light are typical of today's contemporary art spaces, but also maintain the aesthetic of Lisson's other galleries. The public will access the space via 24th Street, while the 23rd Street entrance will be reserved for staff purposes and private functions.
Medgar Evers College Library / ikon.5 architects
United States, Brooklyn, NY, USA -
Design Team
Joseph G. Tattoni, FAIA / Arvind Tikku, AIA / J. Daniel Cummings, AIA / Michael Herbst, AIA / Benjamin J. Petrick, AIA -
45000.0 ft2 -
Project Year
2016 -
Ford Foundation Renovations by Gensler Approved by New York Landmarks Commission
The Ford Foundation has received Landmarks Preservation Commission (LPC) approval for renovations to its building at 320 E 43rd Street in Midtown Manhattan, reports New York Yimby. Constructed from 1963 to 1967, with a design by Kevin Roche and John Dinkeloo and an atrium garden by Dan Kiley, the building became an instant architectural mecca and was made an individual and interior landmark in 1997. The proposed renovations, designed by Gensler, seek to restore a half century of alterations to the building's appearance, in addition to subtle changes to adhere to adhere to fire and accessibility codes.
Hou De Sousa Win Two Competitions with Raise/Raze and Sticks Proposals
Hou de Sousa (Nancy Hou and Josh de Sousa) have recently won two competitions for temporary installations in Washington DC and New York, both using salvaged materials. The first, Raise/Raze, is the winning proposal for DC's Dupont Underground, an abandoned trolley station repurposed as a contemporary arts and culture space. The project reuses the balls from Snarkitecture's "The Beach" installation at the National Building Museum for a new environment-generating initiative, which opens on April 30.
As winners of the 2016 Folly Competition held by the Architectural League of New York, Hou de Sousa will also soon build a pavilion in Socrates Sculpture Park, in Queens. A simple wooden canopy, the structure is a multi-purpose space made of standard dimensional lumber, but has been accentuated with shingles of scrap wood found on-site. Known as Sticks, the pavilion will open to the public on July 9.
New Renderings Released of Robert A.M. Stern Architects' TriBeCa Condos
Several new renderings have been released of Robert A.M. Stern Architects' TriBeCa condos at 70 Vestry Street, according to New York YIMBY. Located next to the West Side Highway in TriBeCa in New York, the 14-story building will contain 46 condos and over 153,000 square feet of residential space, with each apartment ranging from 1,700 to 7,000 square feet.
Heatherwick's Pier 55 Green-Lighted by New York Supreme Court
Pier 55, the floating park designed by Heatherwick Studio and landscape architecture firm, Signe Nielsen, received a green-light from the New York Supreme Court this past Friday, April 8, according to a report by the Architect's Newspaper. Floating above the Hudson River on the Lower West Side of Manhattan, the park is anchored by an aggregation of enormous petal-like stilts that are submerged in the water below. The park is being funded by the philanthropy of Diane von Furstenberg and her husband Barry Diller.
Pier 55's legal troubles began last spring when the non-profit, City Club of New York filed a lawsuit against Pier55 Inc. and Hudson River Park Trust (HRPT) to stop the project.
Summer Program: The Business of Architecture
Syracuse Architecture along with IE Business School and IE School of Architecture and Design have teamed up to offer an innovative summer course: The Business of Architecture. The six-week, 3-credit hour-long course will be conducted at the state-of-the-art Fisher Center, home of Syracuse Architecture in New York City. This course is intended for those studying for a professional degree in architecture (B.Arch and M.Arch) as well as for young professionals and qualified students in related design fields.
ODA Unveils New Residential Towers for Brooklyn
New York-based ODA has revealed their design for new residential towers in Brooklyn's Williamsburg neighborhood. These three towers, called 416-420 Kent, aim to revitalize the neglected East River waterfront and will introduce a new sense of community, while providing ample natural light and green spaces for residents.


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14 February 2014
Just Add Ink Challenge #202 - Just Add Stripes
Hello peeps!! It's Friday and that means one thing ... well two things if you include that the weekend is just around the corner. But it also means that it is time for another challenge over at
Just Add Ink!
This week the challenge is to use stripes on your project.
I chose to use some pretty striped paper on my card this week.
Stamps: My Favorite Things
Paper: Kaiser Craft
Other: Seam binding by Stampin' Up!, charm, Kaiser pearls, Nestabilities.
1 comment:
So soft and pretty Jodene. I love the little Dragonfly embellishment!
19 February, 2014
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Yes, Moab is great for beginners. The absolute scariest ride we went on was the bridge over the Colorado River. No shoulder, no bike lane, praying that a diesel gust wouldn't blow anybody over the puny railing. First ride was up the old Moab Highway; totally nontechnical, plenty of small bumps. My wife was too fast for me to keep in the viewfinder. The gravity was so intense we nearly fell over waiting for the camera to go off.
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BRIEF-Cowen and CEFC China announce strategic partnership
* Cowen Group Inc - CEFC China also agrees to provide $175 million in new debt financing to Cowen
March 3 UIL Holdings Corp said it would buy Philadelphia Gas Works, the largest municipally owned natural gas utility in the United States, for $1.86 billion in cash to expand its natural gas distribution operations.
City officials will use the proceeds to prop up Philadelphia's grossly underfunded pension system, they said on Monday. The sale, which is the biggest transaction the city has ever conducted, must still be approved by the City Council and Pennsylvania utility regulators.
Philadelphia Gas Works, founded in 1836, manages a distribution system of about 6,000 miles of gas mains and service pipes supplying nearly 500,000 customers in Philadelphia.
The deal, which includes some liabilities of Philadelphia Gas Works, brings Connecticut-based UIL close to the gas-rich Marcellus and Utica shales.
Philadelphia Mayor Michael Nutter had been pushing for the sale of the 177-year-old utility since 2010, saying a sale would help the company discharge its liabilities and exploit its natural gas business.
After paying off PGW's bond obligations and putting aside funds for other liabilities, including reserve funds and PGW's own pension plan, Philadelphia will have between $424 million and $631 million to put into the city's retirement system.
The city's pension fund for firefighters, police and other public employees had $5 billion of unfunded liabilities as of July 1, 2012, and was funded at a paltry 48 percent. Eighty percent funded is considered healthy.
"UIL submitted the highest bid for PGW and agreed to contract terms that were important to the city," Nutter said in a statement.
Among those terms, the deal keeps rates frozen for three years and maintains discount programs for seniors and low-income families.
UIL said on Monday that it had secured a $1.9 billion loan from Morgan Stanley Senior Funding Inc to fund the deal. UIL anticipates closing by the first quarter of 2015.
Tudor, Pickering, Holt & Co was the lead financial adviser to UIL and Morgan Stanley was the financial adviser. Sullivan & Cromwell LLP served as UIL's legal counsel. Ballard Spahr LLP represented the city of Philadelphia in the transaction.


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- Theoretical Food Cost – See exactly how to save money, by comparing actual food costs to what costs should have been for any item… the difference is money wasted. An incredibly powerful tool for restaurant managers and executives alike. Watch the video below to learn about why actual vs. theoretical food costs are such a big deal.
- Sales and Cash Reconciliation – Capture mission critical data including over/short, guest counts, comps and discounts, credit card transactions, bank deposits, catering activity, day-part analysis, voids, and much more.
- Loss Prevention – Identify fraudulent activities though alerts and trend tracking. Monitor high cost ingredients, isolate critical areas, and track user-specific activities to reduce any dishonest behavior. Take preventative measures to ensure that loss prevention is minimal.
Better planning eliminates waste
- Menu Engineering – Engineer more profitable menus by analyzing customer demand, item percentage sales contributions, and costs and profit margins. Launch more effective campaigns by understanding the true plate costs of a new recipe, LTO or promotion – before rollout.
- Suggested Order – Simplify ordering at the store-level with system-generated suggested ordering based on par levels, historical consumption patterns, sales forecasts and on-hand inventory levels.
- Demand-based Production – Reduce the costs associated with over-production by forecasting your food production schedule based on sales forecasts and historical consumption patterns. Build custom production schedules by hour, shift, day, week, or by prep station, and adjust plans daily and intra-day, based on traffic and consumption.
Greater accuracy means information you can trust
- Perpetual Inventory Management – Cut costs by maintaining optimal inventory levels – reduce excess inventory waste while avoiding out of stock incidents. The 100% web-based solution allows for real-time tracking of all items – from ordering to depletion. This is one of the most important benefits of using restaurant inventory software.
- Simple Configuration – Save time and eliminate data entry errors by configuring the system for shelf-to-sheet inventory counts in every restaurant, every time.


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Monday, April 12, 2010
Cocoa and Theodore, My Poochies
Here are the poochies. I was reclining on the double chaise lounge, yesterday, enjoying the beautiful Illinois weather. Guess who had the other half?
Hope you all have a great Monday!
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Good Morning Robin! Cocoa and Theodore are very handsome dogs. Bentley would probably like to meet them, but only on the other side of the fence. He gets a bit intimidated by bigger dogs. He used to play with Camilla, the yellow lab who lives next door, when she was a puppy. Now that she's full grown he is a little overwhelmed by her size. But they like to get nose to nose through the fence pickets and wag their tails!
Susan and Bentley
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text: Liberation of Slaver's Bay Category page 3,598pages on this wiki Add New Page Edit History Talk0 Sorting type: Most visited Most visited Alphabetical | Pages in category "Liberation of Slaver's Bay" Liberation of Slaver's Bay Second Siege of Meereen Sack of Astapor Siege of Meereen Battle of Yunkai " The Siege of Astapor is a battle that takes place during Daenerys Targaryen's campaign to... Siege of Astapor Uprising in Meereen Ad blocker interference detected! Wikia is a free-to-use site that makes money from advertising. We have a modified experience for viewers using ad blockers Wikia is not accessible if you've made further modifications. Remove the custom ad blocker rule(s) and the page will load as expected. Categories: Wars


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If Al Pacino played video games, that's what he'd say about this week's GameHounds episode.
Why? Because on this episode, in addition to the regular industry and news coverage, Edie Sellers and Commander Tim chat up Mike Manzanaras of Aksys Games, producer of Blaz Blue: Calamity Trigger for the Xbox 360 and PS3, Bit.Trip.Beat and Bit.Trip.Core, and a host of other goodness. Check out their interview, stay for the great commentary. Topics include:
- Best Buy is price matching new games for used game prices in Utah. Roadtrip!
- VentureBeat says Fizz Factor is making cutbacks at Double Helix and consolidating the Amaze and Griptonite teams.
- Atomic Games is "pretty much dead," according to sources inside the company.
- Valve is rumored to be looking to add sign language into a future Half Life episode.
- Bobby Kotick is an ass. No really. He's a total douchebag.
- Random stuff, thank yous and more.


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Thursday, 22 April 2010
Salmon Hole, California.
As a water baby, I'd love a huge print of this photo of a swimming hole in Chico, California to hang in my living room and gaze at on an overcast, London day. By Younga Park from 20x200.
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