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|Publication number
|Publication type
|Application number
|Publication date
|Dec 1, 1992
|Filing date
|Apr 27, 1990
|Priority date
|Apr 27, 1990
|Fee status
|Publication number
|Ernest W. Long
|Original Assignee
|Pb Diagnostic Systems Inc.
|Export Citation
|BiBTeX, EndNote, RefMan
|Patent Citations (12), Referenced by (83), Classifications (10), Legal Events (8)
|External Links: USPTO, USPTO Assignment, Espacenet
This invention relates to assay cartridges suitable for use in automated analytical systems employing a conveyor for transport of such cartridges among various work stations and, more particularly, to a cartridge which is provided with a spring catch for securing the cartridge in a nest on the conveyor.
Various types of chemical tests can be performed by automated test equipment, an example of testing of considerable interest being the assay of biological substances for human health care. Automated test equipment allows large numbers of test samples to be processed rapidly. Such equipment is employed in health care institutions including hospitals and laboratories. Biological fluids, such as whole blood, plasma or serum are tested to find evidence of disease, to monitor therapeutic drug levels, etc.
In the automated test instrument a sample of the test fluid is typically provided in a sample cup and all of the process steps including pipetting of the sample onto an assay test element, incubation and readout of the signal obtained are carried out automatically. The test instrument typically includes a series of work stations each of which performs a specific step in the test procedure. The assay element or cartridge is typically transported from one work station to the next by means of a conveyor such as a carousel to enable the test steps to be accomplished sequentially. The conveyor usually carries a plurality of the assay cartridges, each secured to a specific location on the upper surface of the conveyor. In the usual arrangement, the assay cartridges are spaced apart from each other in berths which are located along the periphery of the conveyor to facilitate automatic insertion and extraction.
It is necessary to construct the berths for the assay cartridges in a fashion which permits the cartridge to be inserted readily without any binding along the walls of the berth. Such binding or any other such impediment would interfere with precise placement of the cartridge within its berth. Similarly, upon extraction of the cartridge, there should be no binding or other impediment which might interfere with the operation of the automated analytical instrument. Consequently, it has been the practice to construct the berths with smooth interior surfaces which allow the cartridges to be slid readily into and out of the berths.
Another important consideration is the need to ensure that the assay cartridges are precisely positioned on the conveyor and further, that they are not displaced from their positions during movement of the conveyor. The precise positioning of the assay cartridges is necessary for proper operation of the instrument. For example, the fluid dispensing assembly typically includes a pipette which obtains sample fluid from a sample cup and is then transported to the assay cartridge to dispense the required volume of sample fluid. Any excessive misalignment of the pipette with assay cartridge could result in spillage or an incorrect volume being deposited on the assay element thereby causing inaccurate test results.
As a result of the aforementioned smooth-walled berths and correspondingly smooth-walled assay cartridges, the latter may not be held as securely in their respective positions as would be desirable. Accordingly, it is an object of this invention to provide an assay cartridge which can be securely held in its required location on a conveyor while at the same time being readily inserted into and removed from such location.
These and other objects and advantages are accomplished in accordance with the invention by providing an assay cartridge comprising a housing which includes a circumferential sidewall, a top wall and at least one aperture to permit fluids to be provided to a reaction zone within the cartridge. The housing may be molded as a unitary structure from a suitable polymeric material which may be clear or opaque and may include a colorant. The polymeric material is inert to the fluids utilized in the test procedure. The cartridge also may include a base member which is adapted to be inserted inside the bottom periphery of the housing.
A perimetric portion of each side of the sidewall extends therefrom to form a ledge. The berths of the conveyor into which the assay cartridge are to be inserted are constructed each with opposed sidewalls connected by an end wall, the sidewalls and the end wall upstanding from a floor of the berth. An opening opposite the end wall serves as an entry port by which a cartridge is inserted into the berth. A portion of each sidewall, away from the floor, protrudes in the manner of a shoulder to form a groove between the shoulder and the floor of the berth. The groove receives the ledge of a cartridge. This permits a cartridge to be inserted into a berth with the cartridge ledge captured by the berth groove. The sidewall shoulders of the berth contact both sides of the cartridge, and the end wall of the berth contacts a front end of the cartridge to accurately position the cartridge with respect to a plane, normally a horizontal plane, of the conveyor. The groove and the ledge interact to accurately position the cartridge on the conveyor.
In accordance with a further feature of the invention, the cartridge is retained within its berth by means of a spring catch molded integrally with the ledge of the cartridge. The catch is formed by a tongue on each side of the cartridge, the tongue being a part of the ledge and extending in a longitudinal direction of the cartridge. A portion of the material of the ledge, in the shape of an elongated curved slit, is deleted from the ledge to define each tongue. A spring force of the tongue produces pressure between opposed top and bottom surfaces of the groove as the tongue enters the groove upon insertion of the cartridge into the berth. A portion of the floor of the berth is recessed to form a depression at the site of the groove to relieve the pressure of the tongue and, thereby, form a mild snap action by which the spring action of the tongue tends to retain the cartridge against longitudinal movement within the berth. While the snap-action force of the tongue is sufficient to retain the cartridge in its position during motion of the carousel, the snap-action force is readily overcome by an eject mechanism for ejection of the cartridge from its berth at the completion of a test procedure.
The aforementioned aspects and other features of the invention are explained in the following description, taken in connection with the accompanying drawings wherein:
FIG. 1 is a stylized view, partially diagrammatic, of a test system employing cartridges of the invention, the system employing a preferred embodiment of a conveyor, i.e., a carousel for moving the cartridges among various work stations;
FIG. 2 is a fragmentary view of the carousel of FIG. 1, the view including a berth for reception of a cartridge shown also in FIG. 2; and
FIG. 3 is a sectional view of the cartridge, taken along the line 3--3 in FIG. 2.
In FIG. 1 there is shown an analytical instrument 20 which provides automatically a sequence of process steps to accomplish an assay of a test sample. A plurality of cartridges 22 are employed within the instrument 20 to increase the throughput rate, one process step being carried out with one cartridge concurrently with the performance of other process steps with other cartridges. The cartridges 22 are illustrated with respect to a preferred embodiment thereof which includes one or more chambers in the housing. Such chambers may be configured as wells, or reservoirs, for the storage and/or mixing of fluids which are used in the assay procedure or the chambers may culminate in an opening to permit fluids to be provided to a reaction zone within the cartridge. The chambers are formed, integrally within the housing of the cartridge.
The analytical instrument 20 includes a turntable or carousel 24 which is rotated about an axle 26 by a motor 28. By way of example, the motor 28 may be mechanically coupled to the carousel 24 by a gear 30. The carousel 24 carries the cartridges 22 from one work station to another work station, two such work stations 32 and 34 being shown, by way of example, in FIG. 1. The carousel 24 rotates within a temperature controlled chamber 36 having a heater 38 for maintaining a desired temperature at the various work stations so as to allow for a process step of incubation.
Work station 32 is a pipetting station whereat sample fluid and any other required test reagents are delivered to the assay cartridges 22. By way of example, there are shown two pipettes 40 and 42. Preferably, the pipettes are utilized with disposable pipette tips (not shown), each disposable tip being used for delivery of one fluid only and then discarded so as to avoid contamination which could lead to errors in the assay result. The pipettes 40 and 42 are positioned and operated by a pipette mechanism 44 mechanically connected to the pipettes 40 and 42, as indicated by dashed lines.
During the assay procedure, as a result of the reaction(s) and/or interaction(s) between the sample fluid and the test reagent(s) which take place, a detectable change is effected corresponding to the presence of an analyte or component of interest in the sample fluid. The detectable change may be a color change which may be read spectrophotometrically such as with a densitometer or, in an assay method based on fluorescent-labeled biologically active species or one which involves the generation of a fluorescent species as a result of a reaction between test reagents, a fluorescent output signal can be generated and read spectrofluorometrically. Such detectable changes may be read from above or below the assay cartridge. At work station 34 there is shown by way of example a fluorometer 46 for irradiating the reaction zone within the assay cartridge and for measuring the fluorescence emitted from the fluorescent species present therein.
The carousel 24 may be arranged so as to accomodate varying numbers of assay cartridges 22. Each position, or berth, 54 for holding an assay cartridge is provided in this embodiment with a small aperture 56 to allow the irradiating illumination to reach the reaction zone in the assay cartridge and to permit the reflected fluorescent emissions to be collected and measured. Also shown is an injector 58 for inserting a cartridge 22 in an empty berth 54, the injector 58 having an arm 60 for gripping a cartridge 22 during the insertion operation. The injector 58 also serves to extract a cartridge from a berth 54 by use of the arm 60 upon completion of a test procedure. Operation of the motor 28, the pipette mechanism 44, the fluorometer 46 and the injector 58 are synchronized by means of a timing unit 62.
As noted previously, the assay cartridge of the invention may be provided in various configurations and may include one or more chambers such as reservoirs for holding test reagents or for mixing test reagents, or such as wells for permitting fluid reagents to be provided to a reaction zone within the cartridge. FIGS. 2 and 3 show details of the construction of a preferred assay cartridge 22 and the insertion of the assay cartridge into a berth 54 on the carousel 24.
The assay cartridge 22 is contructed of a housing 64, the housing 64 including an insert 66 to facilitate construction of the cartridge 22. A front reservoir 68 and a back reservoir 70 are formed within the housing 64 for containing fluid reagents. A mixing bowl 72 is formed within the insert 66 for mixing reagents, which reagents may be obtained from either of the reservoirs 68 and 70 as well as from reagents delivered by the pipettes 42 and 44 from an external reservoir (not shown). Reagents can be applied to the reaction zone of the assay cartridge through access port 76 formed within insert 66. Dispenser 78 can also be used to provide fluid reagents to the reaction zone. Bottom window 80 is provided for irradiating the reaction zone with readout illumination.
The housing 64 has the general shape of a boat and includes sidewalls 82 and 84 which are joined together by a front wall 86 and a back wall 88, the four walls 82, 84, 86 and 88 upstanding from a base plate 90. The four walls 82, 84, 86, 88, and the plate 90 are molded from plastic as a unitary structure. A first ledge 92 extends horizontally from the plate 90 and from the bottom of the sidewall 82, and a second ledge 94 extends horizontally from the plate 90 and from the bottom of the sidewall 84.
The insert 66 comprises a set of walls 96 which extend in a generally vertical direction downwardly from a top flange 98 of the insert 66, the top flange extending horizontally from the wall 96 to contact and to rest upon the sidewalls 82 and 84. The four walls 96 define the port 76. The bottom window 80 is formed within the base plate 90. At the sides of the bottom window 80, as shown in FIG. 3, the plate 90 is formed with shoulders 100 into which walls 96 depend, bottom edges of the walls 96 coacting with the shoulders 100 to form a guide 102 for locating a fibrous pad 74 in the bottom of the cartridge 22. Bottom edges of the walls 96 contact a top surface 104 of the pad 74, while the shoulders 100 contact a bottom surface 106 of the pad 74. The central portion of the fibrous pad serves as the reaction zone in the assay cartridge shown.
The berth 54 comprises a floor 108 which is depressed from the top surface 110 of the carousel 24. The floor 108 is surrounded by sidewalls 112 and 114 and an end wall 116 which extend from the floor 108 to the carousel surface 110. The end of the berth 54 opposite the end wall 116 is open to serve as a port for insertion of a cartridge into the berth 54. The aperture 56 is located within the floor 108. Shoulders 118 extend from each of the sidewalls 112 and 114 in a direction generally parallel to the floor 108 to form grooves 120 between the shoulders 118 and the floor 108. The locations of the shoulders 118 are retracted from the ends of the sidewalls 112 and 114 towards a more central location of the sidewalls 112 and 114. An outer circular surface 122 of the carousel 24 is provided with a chamber 124 at the site of the berth 54, the chamber 124 extending along an interfacing edge of the surface 122 with the floor 108 and each of the sidewalls 112 and 114 of the berth 54. The chamber 124 facilitates alignment of the cartridge 22 with a berth 54 during insertion of the cartridge 22 into the berth 54 by the injector 58 (FIG. 1).
In accordance with the invention, the ledges 92 and 94 slide within the grooves 120 upon insertion of the cartridge 22 in the berth 54. Opposite sides of the grooves 120, constituted by the floor 108 and the underside of each of the shoulders 118, are spaced apart by a distance equal to a thickness of the ledges 92 and 94 plus a slight clearance space to facilitate entry of the ledges 92 and 94 within the corresponding grooves 120 so as to secure the cartridge 22 within the berth 54 with respect to a vertical direction perpendicular to a top surface 110 of the carousel 24. The shoulders 118 are spaced apart from each other with a distance equal to the width of the cartridge 22 plus a slight clearance for accurately locating the cartridge 22 in the berth 54 with respect to a horizontal direction parallel to the top surface 110 of the carousel 24.
In accordance with a feature of the invention, each of the ledges 92 and 94 is provided with a cantilevered tongue 126 formed within the process of forming the housing 64 by deleting material of each of the ledges 92 and 94 in the form of an elongated slit 128. In each of the ledges 92 and 94, the end of the tongue 126 closest to the rear of the cartridge 22 is attached to the ledge 92, 94 while the opposite end of the tongue 126 is free to be displaced in the vertical direction against a restoring spring force of the tongue 126. At each of the grooves 120, a depression 130 is formed within the floor 108 of the berth 54 to facilitate reception of the tongue 126 upon insertion of the cartridge 22 within the berth 54. A central portion 132 of the tongue 126 is enlarged in the vertical direction for contacting the shoulder 118, during insertion of the cartridge 22 within the berth 54, and for bending the tongue 126 downward into the depression 130 as the back end 134 of the tongue 126 clears the back end 136 of the depression 130. This may be likened to a snap action in which the back end 134 of the tongue 126 is displaced in the vertical direction alongside the back end 136 of the depression 130 to lock the cartridge 22 within the berth 54, and hold the cartridge 22 with its front wall 86 in abutment to the end wall 116 of the berth 54. It is noted that while only the groove 120 of the sidewall 114, and only the tongue 126 of the ledge 92 are shown in FIG. 2, the foregoing description applies equally to the tongues 126 in both of the ledges 92 and 94 and to both of the depressions 130 alongside the sidewalls 112 and 114. As an additional constructional feature, pods 138 may be provided in forward and aft portions of the cartridge 22 under each of the ledges 92 and 94 to facilitate the sliding movement of the cartridge 22 along the floor 108 of the berth 54. The back end 136 of the depression 150 is angled relative to the plane of the floor 108 to facilitate a lifting of the back end 154 of the plane 126 out of the depression 130 upon extraction of the cartridge 22 from the berth 54.
The foregoing construction provides for an accurate positioning of the cartridge 24 within the berth 54 in three dimensions, namely, the vertical direction perpendicular to the top surface 110 of the carousel 24, and two horizontal directions parallel to the surface 110, namely, the tangential and the radial directions of the carousel 24. The sidewalls 112 and 114 with their shoulders 118 act as a guide for positioning the cartridge 22 in the tangential direction, the grooves 120 serve as a guide for positioning the cartridge 22 in the vertical direction, and the locking of the back ends 134 of the tongues 126 in the back ends 136 of the depressions 130 serve with the abutment of the front of the cartridge 22 against the end wall 116 as a guide for positioning the cartridge 22 in the radial direction. Accordingly, the assay cartridges are held precisely and firmly in the desired locations and are not displaced to any significant extent when the carousel is rotated quickly to carry a particular assay cartridge to a work station in order that a method step may be performed.
The assay cartridges of the invention may include test reagents for performing any of various analytical test methods including those based on chemical reactions, immunometric interactions, etc. Although these assay cartridges are preferably utilized for the analysis of biological fluids such as plasma, serum, etc., it will be evident to those skilled in the art that the cartridges may be used to carry out analyses of any fluid. In a preferred embodiment the assay cartridges are used to carry out immunometric assays for an analyte of interest, e.g., an antigen or an antibody. Such assays, as well as the other types which can be carried out with the assay cartridges of the invention are well known to those skilled in the art and extensive discussion thereof is not required here. By way of illustration the use of the assay cartridge shown in FIGS. 1-3 will be described in conjunction with a sandwich immunoassay for an antigen of interest. In assay cartridge 22, the thin porous member 74, which may be a fibrous mesh pad, a porous membrane or the like serves as the location where the immunometric interactions take place. In this preferred embodiment the porous member 74 extends from the dispenser 78 to a chamber (not shown) in the front of the housing 64 which holds a fluid absorbing material (not shown). In this assay an antibody raised against the antigen of interest is initially applied to the porous member 74 and immobilized therein prior to the pad being incorporated into the assay cartridge 22. Applicaton of the antibodies to the porous member and immobilization of the antibodies therein can be accomplished by any of various known techniques. For example, a fluid containing the antibodies can be applied to the porous member and the member subsequently dried to provide a porous member having the antibodies distributed throughout and held therein by the structure of the member. In other embodiments, particularly where the porous member comprises a fibrous mesh material, antibodies can be chemically bound to polymeric particles and the fibrous mesh impregnated with an immunocomplex of the antibodies. In this manner the antibodies are immobilized in the fibrous paid and remain therein throughout the assay process.
In the assay process a volume of sample fluid, typically 20-30 μl, is aspirated into a pipette from a sample cup and deposited on the porous member 74 through access port 76 while the assay cartridge 22 resides on the carousel 24. The sample fluid is drawn throughout the porous member via capillary action and the assay cartridge is allowed to incubate for a suitable period at the appropriate temperature to allow the sample antigen to interact with the immobilized antibodies dispersed throughout the member. Subsequently, a foil cover (not shown) which is secured about the mouth of reservoir 68 to form a seal over a solution of an enzyme-linked antibody (an antibody directed to the same antigen as is the antibody immobilized in the porous member), is perforated by means of a pipette, 40 or 42, carrying a disposable tip and a desired volume of the enzyme-linked antibody solution, typically 10-20 μl, is aspirated into the pipette tip. The solution is then deposited onto porous member 74 through access port 76 and drawn throughout the member by capillary action. The assay cartridge 22 is again allowed to incubate to permit the interactions between the enzyme-linked antibodies and the sample antigen to occur thus forming the ternary complex with the immobilized antibodies and the sample antigens. Since the enzyme label must be detected indirectly, a desired volume, typically 50-100 μl, of a solution of a substrate for the enzyme is applied to the porous member. This is accomplished by piercing the foil covering (not shown) of reservoir 70 with a disposable pipette tip carried by pipette 40 or 42 and aspirating the desired volume into the pipette tip. This substrate solution is utilized both as a wash fluid to remove from the porous member any unbound sample antigen and enzyme-linked antibodies and to render the enzyme label detectable. The substrate solution is deposited into the dispenser 78. The substrate solution exits the dispenser and is guided into the porous member 74. As the substrate solution propagates through the porous member 74 it forces any unbound sample antigen and enzyme-linked antibody together with the fluid out of the porous member and into the absorber chamber where they are taken up by absorber material. The duration of this step is approximately 1-2 minutes. The signal provided by the fluorescent species liberated by the reaction of the enzyme with the substrate material is read by means of the fluorometer 46.
It will, of course, be evident that the assay process described above can be modified by utilizing a separate wash fluid such as water to replace the fluid in the porous member and guide area and to remove unbound antigens and enzyme-linked antibodies. In this procedure the substrate solution is applied to the porous member after the wash fluid.
In another preferred embodiment a thin multilayer assay element is incorporated in the assay cartridge. Such multilayer assay elements for use in automated analytical instruments are well known to those skilled in the art.
Although the invention has been described with respect to a specific preferred embodiment it is evident that this is illustrative only and other embodiments of the invention will be apparent to those skilled in the art.
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|Apr 14, 2004
|Mitsubishi Kagaku Medical Inc
|Automatic measuring cartridge and measuring method using it
|Apr 27, 2001
|Mar 7, 2007
|Mitsubishi Kagaku Iatron, Inc.
|Measuring method and instrument using a cartridge
|Oct 6, 2014
|Jun 7, 2017
|Access Medical Systems Ltd
|Cartridge assembly tray for immunoassay tests
|Oct 4, 1993
|Apr 28, 1994
|Baxter Diagnostics Inc.
|Assay cartridge
|Dec 13, 2005
|Sep 14, 2006
|Cholestech Corp
|Automated immunoassay cassette, apparatus and method
|Jun 21, 2006
|Jan 4, 2007
|Paavo Kinnunen
|Method and device for forming a liquid-liquid interface, especially for surface tension measurement
|U.S. Classification
|422/404, 436/47, 422/64
|International Classification
|Cooperative Classification
|European Classification
|Apr 27, 1990
Owner name: PB DIAGNOSTIC SYSTEMS, INC., MASSACHUSETTS
Free format text: ASSIGNMENT OF ASSIGNORS INTEREST.;ASSIGNOR:LONG, ERNEST W.;REEL/FRAME:005295/0880
Effective date: 19900427
|May 1, 1995
Owner name: BEHRING DIAGNOSTICS, INC., MASSACHUSETTS
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Effective date: 19931231
|May 23, 1996
|Fee payment
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|Oct 3, 1997
Owner name: BEHRING DIAGNOSTICS GMBH, GERMANY
Free format text: ASSIGNMENT OF ASSIGNORS INTEREST;ASSIGNOR:BEHRINGWERKE AKTIENGESELLSCHAFT;REEL/FRAME:009168/0310
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Effective date: 19970721
|Oct 14, 1999
Owner name: BEHRINGWERKE AG, GERMANY
Free format text: CONFIRMATION OF ASSIGNMENT AUTHORITY;ASSIGNOR:BEHRING DIAGNOSTICS INC.;REEL/FRAME:010299/0809
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|Jun 27, 2000
|Maintenance fee reminder mailed
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|Lapse for failure to pay maintenance fees
|Feb 6, 2001
|Expired due to failure to pay maintenance fee
Effective date: 20001201

subset: commoncrawl


text:
Added to Cart
Kambrook Stainless 4L Deep Fryer (KDF560BSS)
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Kambrook Stainless 4L Deep Fryer (KDF560BSS)
Large 4L capacity for families or commercial kitchens.
+ Delivery
Leaves warehouse in 1-2 business days
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Crispy chips, perfect tempura and tender fried chicken are now within easy reach with this safe and efficient deep fryer.
- Large 4 litre oil capacity
- 1kg basket capacity
- Easy clean non-stick removable bowl
- Variable temperature control
- Cool touch handles
- Stylish stainless steel exterior
- 2200 watts of power
- Removable elements for easy cleaning
- Large viewing window
- Removable anti-odour charcoal filter
Whether you're at home or in a commercial kitchen, the large capacity and innovative features of the Kambrook Stainless 4L Deep Fryer is a great choice.
The safety lid features a large viewing window so you can keep an eye on things without the risk of oil splashes, and the quick-heating, adjustable temperature controls offer great versatility for a wide range of foods.
This Product is offered and supplied by Dick Smith pursuant to the Terms and Conditions.


text:
2017 Brush of the Month Club - February Brushes
$ 10.00
These are the February 2017 brushes, part of the 2017 Brush of the Month Club
The brushes this month are from old vintage documents. Some of them are small, but they were so amazing I just had to use them. The clean up on these was a labor of love but I hope that you enjoy them as much as I do!
67 Count brush file with individual .png files
Special unlimited use personal or commercial license as long as they are incorporated into your own work and not shared as is.
Do you want all 12 packs for one amazing price? Get these brushes and more in the 2017 Brush of the Month Club
ARE YOU A MEMBER OF MY "ART JOURNAL EMPORIUM"? If you pay monthly for Subscription B or C, these brushes are NOW INCLUDED in your membership!


text:
- Pleurodynia
- Pleurodynia Pleu`ro*dyn"i*a, n. [NL., fr. Gr. ? side + ? pain.] (Med.) A painful affection of the side, simulating pleurisy, usually due to rheumatism. [1913 Webster]
The Collaborative International Dictionary of English. 2000.
The Collaborative International Dictionary of English. 2000.
Pleurodynia — Also known as Bornholm disease, this is a temporary illness that is a result of virus infection. The disease features fever and intense abdominal and chest pains with headache. The chest pain is typically worsened by breathing or coughing. The… … Medical dictionary
pleurodynia — /ploor euh din ee euh/, n. Pathol. 1. pain in the chest or side. 2. Also called epidemic pleurodynia, devil s grip. an epidemic disease caused by a coxsackievirus, characterized by sudden chest pain, mild fever, and recurrence on the third day of … Universalium
pleurodynia — n. chest pain, pain of the side … English contemporary dictionary
pleurodynia — pleu·ro·dyn·ia … English syllables
pleurodynia — n. severe paroxysmal pain arising from the muscles between the ribs. It is often thought to be of rheumatic origin … The new mediacal dictionary
pleurodynia — n. pain in muscles of chest or side … Dictionary of difficult words
pleurodynia — noun pain in the chest caused by inflammation of the muscles between the ribs • Syn: ↑pleuralgia, ↑costalgia • Hypernyms: ↑pain, ↑hurting … Useful english dictionary
Pleurodynia epidemica — Klassifikation nach ICD 10 B33.0 Pleurodynia epidemica Bornholmer Krankheit Myalgia epidemica … Deutsch Wikipedia
epidemic pleurodynia — Pathol. pleurodynia (def. 2). * * * … Universalium
epidemic pleurodynia — n an acute epidemic form of pleurisy characterized by sudden onset with fever, headache, and acute diaphragmatic pain and caused by various coxsackieviruses (esp. serotypes of species Human enterovirus B) called also Bornholm disease, devil s… … Medical dictionary


text:
Learn more about MILTONS (LIVERPOOL) LIMITED. Check the company's details for free and view the Companies House information, company documents and list of directors.
Know about every new company document that is added!
Take advantage of our watch this company feature free of charge and have notifications sent directly to your inbox. Whenever a new document appears on this website, or if their particulars change, you will be immediately informed about such changes. To monitor these changes, all you need to do is click on watch this company.
|Tangible Fixed Assets
|£ 20
|Current Assets
|£ 6,076,897
|£ 3,999,865
|Shareholder Funds
|£ 5,178,542
|Profit Loss Account Reserve
|£ 5,178,442
|Called Up Share Capital
|£ 100
|Total Assets Less Current Liabilities
|£ 5,178,542
|Net Current Assets Liabilities
|£ 5,173,709
|Creditors Due Within One Year
|£ 903,188
|Cash Bank In Hand
|£ 626,250
|Stocks Inventory
|£ 1,450,782
|Share Capital Allotted Called Up Paid
|£ 100
|Number Shares Allotted
|100 ordinary shares of £1 each
Information about the Private Limited Company MILTONS (LIVERPOOL) LIMITED has been prepared for information purposes only. It is not intended to be nor does it constitute legal advice. This is public information provided by the official company register.


text:
Tiger Woods' Accident May Have Been Caused by Wife's Road Rage
Was Tiger Woods' car crash yesterday a case of DWYWITTBYBIFSSAOH (Driving While Your Wife Is Trying to Bash Your Brains in for Supposedly Screwing Around on Her)?
TMZ reports that there's more to the accident—which occurred at approximately 2:30 a.m. on Friday outside of Woods' Florida home—than was initially reported.
According to a source, Woods admitted in a conversation that he had crashed his Cadillac Escalade into a fire hydrant and tree after getting in a fight with his wife, Elin Nordegren, over rumors that he'd been cheating on her.
Oh, and earlier reports that Nordegren had tried to free her husband from the SUV by smashing the back window with one of Tiger's golf clubs? That might not be entirely accurate.
The source reveals that Woods admitted that, prior to the smash-up, he and Nordegren got into a blow-up over the affair rumors, at which point the Swedish model scratched up hubby's face. (Woods was treated for facial lacerations at Health Central Hospital in Ocoee, Florida, following the accident.)
Woods apparently tried to flee the beat-down in his Escalade, but Nordegren followed him outside and struck the vehicle with a golf club several times as he tried to drive away. At which point a "distracted" Woods struck the fire hydrant and tree.
Huh; well, there goes our theory that the accident was caused by a tryptophan coma that Woods had slipped into after eating too much turkey at Thanksgiving dinner.
Woods and his wife are expected to be questioned about the incident by police sometime this weekend.


text:
Canon Law in the Age of Reform, 11Th-12th Centuries (Collected Studies Series, Cs406)
These articles reflect a common interest in the relationships between canon law and ecclesiastical reform in the 11th and 12th centuries. Many investigate the contribution of two key figures, Humbert, cardinal bishop of Silva Candida, and Pope Gregory VII, after whom the reform movement is named.
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text:
This Eve Gravel "Pierrot" blouse is such a killer piece. Looks really sharp tucked into a colourful miniskirt or high-waisted jeans. I also have just been wearing it untucked like this. Totally doable. Oh, and would you look at that?! My black-and-white glasses match my blouse --- UNINTENTIONAL COORDINATION.
|Eve Gravel 'Pierrot' blouse, $146. Available at all three shops. Chainmaille necklace, $50, by CS Footprints, available at 129 Ossington and Dalhousie location.
Here is Amber wearing this truly incredible monochromatic printed dress from Ursa Minor Studio. We can't tell you how happy it makes us to get in new pieces from Elizabeth Hudson of Ursa Minor. She always finds a brilliant way to incorporate volume in ways that still flatter the body. She also adds cool details like this oversized pocket in the front.
|Ursa Minor Studio 'Youki' dress, $198. Available at 129 Ossington and Westboro locations.
|Leonardo DiCaprio ft. swan. I can hardly explain the serene calm that comes over me as I gaze upon this photo.


text:
House Sitter in Harvey
Hello, my name is Darius, I'm a college student attending Louisiana State University. Currently in New Orleans for the summer. I am great with pets, mainly cats and dogs. I have house sat a few times and had a good experience with all of them. I also can cut your grass if need, I feel like that is a great service that not many can provide when House Sitting. My contact information is
House Sitter Details
|Email Address
|Phone Number
Collect Mail
Feed Pets
Care For Plants
Take Out Trash/Recycling
Snow Clearing
Notes made here will only be seen by you. If you want to message the owner of this listing
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text:
Author Tags: Fishing, Maritime
"Your only master is the weather." -- Margaret Sharcott
With their 13-month-old baby aboard their 30-foot troller Sea Lion, Margaret Sharcott and her husband Stan, a professional fisherman, proceeded to circumnivate Vancouver Island in the winter of 1954. Her account of the 600-mile circuit is a little-known but very readable memoir, Troller's Holiday (London: Peter Davies; Toronto: British Book Service, 1957), printed in London, England by William Clowes and Sons Ltd. With their cocker spaniel Skipper aboard, the Sharcotts nosed out of their home village of Kyuquot soon after Christmas and headed north for Bull Harbour on Hope Island for their first holiday in five years. Gales, fog, ice, ports of call, humour and danger abound during their trip which is also recorded in a series of 11 black & white photographs. The emphasis in Troller's Holiday is on coastal culture; there is little personal information about the dynamics of the Sharcotts themselves, who switched to the 36-foot troller Thornton Island for the final homeward leg of their journey from Victoria to Kyoquot. She concludes, "You are your own captain. You go where you want when you want. Your only master is the weather. You wear your old clothes. There are no timetables printed in a city office to dictate to you. This is the life!"
A Troller's Holiday was followed by Sharcott's memoir of accompanying her husband, a commercial fisherman, through the hazardous waters off the west coast of Vancouver Island.
Troller's Holiday (London: Peter Davies; Toronto: British Book Service, 1957)
A Place of Many Winds (Toronto: British Book Service, 1960)
[BCBW 2004] "Maritime" "Jacket" "Fishing"


text:
|Message view
|« Date » · « Thread »
|« Date » · « Thread »
|"Greg Sims" <g...@headingup.net>
|Large Resource Consumption by One User Access to mp3 File
|Thu, 08 Feb 2007 16:17:09 GMT
I originally posted this to the User Support forum and received no replies in over two weeks. I appreciate your help with this in advance! The Apache Service is stopping as a result of a single user accessing one or two mp3 files. I gathered some log data to detail the problem: http://raystedman.org/4204Ref.txt contains a log sequence that accesses one mp3 file by one user. http://raystedman.org/mp3/4204.mp3 is the mp3 <http://raystedman.org/mp3/4204.mp3%20is%20the%20mp3> being accesses which is almost 7 MB large. Normally I will only see one record in the access_log for a transfer like this one. This transfer contains 30+ records over 12 minutes from the same user to the same file. It may be that this user is one a system with limited buffer resources and/or a modem connection to the internet. http://raystedman.org/22Stat.txt is a server-status that the aftermath of all this. Notice the number of workers that were allocated to this one user. This consumption of server resource by one user is unfair to everyone else trying to use http at the same time. Is it possible to control resource allocation so that it is fair to all users? Thanks! Greg PS. The user is working on transferring a group of .mp3 files at the same time. This can be seen at http://raystedman.org/mp3Ref.txt. The server doesn't have much else going on which can be seen here http://raystedman.org/22Ref.txt.
|View raw message


text:
Strong interest as Bakken tours begin
WILLISTON -- Sylvan Prothero built a vacation around touring North Dakota's oil fields.
The Breckenridge, Minn., area farmer was among about 30 people to participate in the first Bakken Field Tour on Saturday.
Prothero said his daughter-in-law thought he was crazy for spending the $325 to go on the tour, but he had been reading about the oil boom and wanted to experience it.
"I just thought I'd like to go out there and see what it's like," Prothero said. "It is amazing."
The series of tours is designed to educate people about oil and gas development in northwest North Dakota, whether they're interested in doing business in the Bakken or just have sheer curiosity.
Saturday's group included real estate developers, private equity investors, representatives from a trucking company and others from around the state and around the country.
Representatives from Alderon Industries of Hawley, Minn., which manufacturers control panels and float switches, attended the tour to learn about opportunities they could pursue in the oil field.
"We didn't really understand the scope of what was going on," said Greg Simon, sales and marketing manager.
The guided tour, which left from Williston and went through Watford City, New Town, Stanley and Tioga, drove by drilling rigs, fracking equipment, gas processing plants, crude loading terminals and new housing developments. It also featured a tour of the Target Logistics crew camp near Tioga.
Participants attended an educational workshop Friday night to lay the foundation for what they saw Saturday.
Chuck Geisen, a real estate developer from Green Bay, Wis., attended the tour even though he's already been working in the Williston area with Landmark Real Estate & Development. Geisen said it expanded his focus and allowed him to network and make new connections.


text:
Young man stabbed, another in police custody after Santa Venera fight
A young man is in hospital with serious injuries after he was stabbed following an argument with another man in Santa Venera early yesterday.
The police said that a 24-yearold was stabbed in a private residence in 4 September 1918 Street.
Another man, a 23-year-old, escaped in a car but was later stopped by members of the Rapid Intervention Unit.
He was also taken to a health centre where he was found to have suffered slight injuries.
Magistrate Joseph Mifsud leading an inquiry. is


text:
Free easy to use script for better traffic ratings.
Use this security logo:
Freeware is computer software that is available for use at no cost or for an optional fee.
Tutorial not found. Let know us about any useful video tutorial.
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Major Update
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text:
Watch more clips from the Emmys 2014 here
The Brits swept up at this year's Emmy Awards 2014.
Actors Benedict Cumberbatch and Martin Freeman took home best lead and supporting actor awards for their roles in hit BBC series Sherlock, while the show's writer Steven Moffat picked up the outstanding mini-series writer gong.
Other British successes at the ceremony included Colin Bucksey taking best director for the mini-series Fargo, in which Martin Freeman starred in the lead role, but there was no such luck for a host of other stars a the event at the Nokia Theatre, Los Angeles.
ITV drama Downton Abbey rated high in the nominations list but neither Michelle Dockery, who plays Lady Mary Crawley, nor her co-stars Dame Maggie Smith, Joanne Froggatt or Jim Carter managed to take the top prize.
Ricky Gervais' Derek missed out to Big Bang Theory's Jim Parsons in the lead actor in a comedy series, while Game of Thrones actress Lena Headey, who plays Cersei Lannister in the HBO hit series, lost out to Anna Gunn, or Skylar White, in Breaking Bad.
In fact it was a bad night for most of those up against the popular crime series, which also took honours for best drama and best lead and supporting actors in Bryan Cranston and Aaron Paul, fighting off Hollywood heavyweights including Kevin Spacey, Matthew McConaughey and Woody Harrelson.
Like this? Did you know we have a dedicated TV and Film page on Facebook?


text:
In the footsteps of Treves — Trent
Trent, Sandford Orcas and Yetminster. Steve White and Clive Hannay follow Sir Frederick to the county's far north-west.
Published in May '09
Trent, once in Somerset, was established as a Dorset village by the time of Sir Frederick Treves's visit in around 1904 or 1905, writing his book, Highways and Byways in Dorset. Trent had been incorporated into Dorset in the county boundary changes of 1896, along with the parishes of Goathill, Poyntington, Sandford Orcas and Seaborough, near Beaminster.
Treves wrote that 'Trent is a straggling, most picturesque village, lying in a valley of orchards. A worn pathway of flagstones leads through the rambling street.' Trent is still very picturesque. The orchards have gone, but much of the paving along the side of the road is made up of old flagstones.
Treves continues: 'It is a village of old stone houses, of thatched cottages, and of many gardens, with no hint of modernness about it. Any inhabitant of a century ago who could revisit the place would find it but little changed.' Whilst there has been some development in Trent since Treves cycled this way, it seems to have been minimal; it must be one of the most unspoiled villages in Dorset. This is largely because 1121 acres of Trent, with a number of farms, cottages and buildings, were purchased by Ernest Cook, grandson of Thomas Cook, the famous travel agent, in 1935. In 1952 the organisation became known as the Ernest Cook Trust and has gone on to buy 2100 acres around Trent. The Trust currently owns and manages landed estates in five English counties.
Treves, moving on to Trent Manor, tells the story of how the future King Charles II, fleeing defeat at the battle of Worcester in September 1651, hid for a total of sixteen days in Lady Ann Wyndham's bedroom. During his stay the King had access to a hiding-place with a double floor under the roof. 'The manor house at Trent stands near the church, in a gracious garden. The building has been much modernised, but the King's hiding-place and the rooms he occupied have been carefully preserved. By the kindness of the lady of the house I was able to see them. Lady Anne Wyndham's room is beautifully panelled with black oak, has massive ceiling beams, quaint window recesses, and secret cupboards for hiding valuables. The King's hiding-place is in a small projecting wing, and is over an ancient brewhouse, which has been allowed to remain unchanged. The entrance to the very narrow cell is through a triangular opening, which is really at the base of a blocked-up stone doorway. The double floor appears to be due to the building of the wing at a different level from that of the house.'
The 'much modernised' manor seen by Treves has to a certain extent been 'de-modernised' since. The previously mentioned Ernest Cook bought the house in 1935 and proceeded to knock down most of the Victorian additions. His death in 1955 meant that he never completed the job, but soon afterwards the present owners purchased the house from the Trust and completed the work. Interestingly, it was not until they had purchased the property that the present owners discovered that their family had lived there in the 1500s.
The house now has a new front, most of the remainder being pre-Victorian. Like Treves, by the kindness of the lady of the house I was able to see the King's room and the hiding-place. The room used by the King and the hiding-place are still preserved as Treves saw them, the only exception being the removal of a stairway in the entrance to the 'very narrow cell', which eliminates the triangular opening mentioned by Treves.
Visiting Trent church, Treves notes: 'The church of Trent is a very gracious building, standing in one of the most beautiful churchyards in the county, where are the shaft and steps of an ancient cross, as well as a venerable chantry house, built in the reign of Henry VI.'
The 15th-century steps and shaft of the ancient cross are still to be seen. The shaft, damaged, as most were, by Cromwell's men, was restored as a memorial to the Great War. The chantry house, built in the mid-15th century, is a splendid building, and is situated in what still is 'one of the most beautiful churchyards in the county.'
Treves, inside the church notes: 'The curious and wonderfully carved bench-ends in the church are brown with age, the rood screen is older still; on the walls over the manorial pew hang rusted helmets and gauntlets…'
The 'bench ends' or pew ends are believed to be from the early 16th century and, like the pews themselves, have unusually escaped the Victorian 'restorers' responsible for the ruin of many a church. The screen must be one of the finest examples of its type and is indeed older than the pew ends; it dates from the 15th century, although it has been restored over the centuries. I searched but could find no sign of the helmets and gauntlets; unfortunately, items like these are often stolen from churches and these may have met the same fate. The church and village are unquestionably worth a trip to see – there is even an excellent public house nearby, originally built as a hostelry for the builders of the spire.
Cycling just over a mile to the north-east, Treves came to Sandford Orcas: 'In the pretty village of Sandford Orcas, near Trent, is a most excellent grey-stone manor house, very tenderly restored. It has a rare gatehouse with chambers over, a porch brave with heraldic carvings and heraldic beasts on gables, and, above all, an old fashioned garden, with a bowling-green suggestive of leisured ease, cakes and ale.'
The manor house itself could hardly have altered at all since Treves' visit. Built in the mid-16th century from local Ham stone, it appears to have more of a mellow honeyed colour than the 'grey' Treves states. The current owner's family has been here for more than 250 years and do not seem to have changed the 'old fashioned garden.' The bowling-green, or at least the site of it, is still evident – whether Treves thought it a bowling-green or saw it being used as such is unknown. The present owner informed me that he can recall his grandparents using the large lawn area as a croquet lawn but has no knowledge of its use as a bowling-green.
Calling at Yetminster, Treves enthuses: 'Yetminster, the chief place near Sherborne, is a picturesque townlet, full of quaint old houses and venerable thatched cottages. The dates on the buildings belong mostly to the early part of the seventeenth century. In the main street is an old thatched-roofed inn, as well as many houses in ancient stone with stone-mullioned windows and fine gables. Most of the dwellings are covered by creepers, and none seems to lack a garden or an orchard. Yetminster is probably the most consistent old-world village or townlet in the county, for of modern buildings it has but few examples. The church has a seventeenth century clock, which plays the National Anthem every three hours.'
Yetminster has suffered an expansion that would not have pleased Sir Frederick Treves and has probably trebled in size. Fortuitously, the older part of the village retains its old buildings and with it a certain charm, as can be seen in Clive Hannay's painting. Likewise, the inn near the church still has its thatched roof and the clock still chimes the national anthem every three hours. Whilst the clock is indeed 17th-century, it only gained its unique chime upon its restoration for Queen Victoria's jubilee in 1897.


text:
Product Description
Zob 18″ Straight Tube – Black/Yellow
NVS Glassworks is proud to be an Authorized Dealer of ZOB Glass! Designing and manufacturing out of California, ZOB Glass is well known in the glass industry for having a huge variety of scientific glass to choose from. They are all faceted with percs made in-house. From the OG line straights & beakers, to bubblers, stemless, wubblers, concentrate rigs, and more, ZOB has something for everyone!
| OG Straight tube design with triple ice pinch
| Perc: Slitted downstem
| Joint: 18mm female
| Label: Black/Yellow ZOB logo
| Height: 18″ (may vary slightly)
| Includes: ZOB 18mm slide
| Blown in California by ZOB Glass


text:
July 11 (Reuters) - Standard & Poor's ratings service cut the Commonwealth of Puerto Rico's general obligation rating to "BB" from "BB+", citing enactment of a new law, which allows certain corporations to restructure their debt.
"We also believe that the enactment of the bill is indicative of the mounting economic and fiscal challenges for the commonwealth as a whole," S&P said. (bit.ly/1wcilqO)
The ratings agency also cut its rating on the Puerto Rico Sales Tax Financing Corporation (COFINA) first lien sales tax bonds to "BBB" from "AA-" and its second lien COFINA sales tax underlying rating (SPUR) to "BBB-" from "A+".
All ratings have been removed from CreditWatch and assigned a negative outlook, S&P said on Friday. (Reporting by Abinaya Vijayaraghavan in Bangalore; Editing by Joyjeet Das)


text:
iGrid ActiveX 3.0 Released
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grid, visual basic, flexgrid, listview, windows xp visual style, outlook, format, string, flag, virtual, validate, edit, multiselect, rowmode, header, gridline, combo, check, color, cell, column, group, scrollbar, background, drag, ole drag-n-drop
Windows XP Visual Styles support, new header options (font, background color, multisort icons), scroll bars related events, OLE Drag-n-drop, row keys, the minimum and maximum column width, the MouseEnter and MouseLeave events for cells and column headers
This product can be freely distributed through the Internet. To publish it on a CD, please contact firstname.lastname@example.com.
Revised: September 25th, 2007
NOTE: This License Agreement can be out-of-date especially if you got this installation from a public shareware catalog or from one of our authorized resellers. The latest effective License Agreement and other rules of our company related to licensing and support can be always found on our website at http://www.10Tec.com/.
This License Agreement ("Agreement") is a legal agreement between you, the developer end user ("Licensee"), and 10Tec Company, located in Kiev, Ukraine. The Agreement is effective the date Licensee installs, downloads, copies or otherwise Uses, in whole or in part, a 10Tec Company software product ("Software Product"), and is limited to the specific version installed, downloaded, copied or otherwise Used by Licensee (herein, "Use", "Uses" or "Used" means to access any of the files that are included with the Software, to develop an application that makes use of the Software, to consult any of the documentation included with the Software, or to otherwise benefit from using the Software). The Software Product is licensed, not sold.
If you do not agree to the terms of this Agreement, promptly destroy the package with the Software Product and the accompanying electronic items, any written materials and binders or other containers should be returned to the place you obtained them from for a full refund if applicable.
10Tec Company grants Licensee the right to install the Software Product, which includes computer software and may include associated media, printed materials, and online or electronic documentation (all of which comprises the Software Product) on an unlimited number of computers and on portable computers operated solely by Licensee for the sole purposes of designing, developing, testing, and deploying application programs.
Licensee is granted the license to Use the Software Product for a period of only thirty (30) days after the first installation of the evaluation version of the Software Product ("Evaluation Period"). After this evaluation period, Licensee shall either (i) delete the Software Product and all related documentation from all computers onto which it was installed or copied, or (ii) contact 10Tec Company or one of its authorized resellers to purchase the Software Product. Licensee may Use the evaluation version of the Software Product for evaluation purposes only. Licensee may not distribute any of the files, in any form or manner, provided with the evaluation version of the Software Product to any parties.
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Best Fantasy Football Loser Punishment
Crunch your numbers and get ready for those drafts, Fantasy Football is back! Most leagues play for money and bragging rights, but others have a lot more riding on the win... like dignity.
Most leagues have some sort of punishment in place for whoever comes in last. Some have gotten tattoos, worn dresses, or had to perform a shameful act. Henry here, may have received the worst punishment of all... an EPIC 2015 calendar...
You can see the rest of his calendar on his Instagram account. Good luck in Fantasy land this season!


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While the principle of portability will definitely help policyholders, a number of issues need to be sorted out before it can see the light of day
Mediclaim portability, under which one can carry over one's 'no-claims' or 'low-claims' medical insurance record to any other provider, is not allowed currently. The issue surfaced once again after Insurance Regulatory and Development Authority (IRDA) chairman J Hari Narayan mentioned about the need for it yesterday at an insurance summit. However, according to industry experts, mediclaim portability will remain a distant dream, for a variety of reasons.
According to Dr Damien Marmion, chief executive, Max Bupa, the only way for portability to work is to have products with the same terms and conditions which also include a no-waiting period for pre-existing conditions. Besides, he feels that to deal with numerous complaints about health insurance, IRDA is thinking about portability as a quick-fix solution. "Instead of attacking the cause of the problem, IRDA is interested in addressing the symptoms," Dr Marmion said.
The CEO of Max Bupa also questioned how any insurance company with the current product portfolio could accept risk of policyholders switching from another company after paying premiums over the years and switching to a new insurer with no waiting period before raising claims. Moreover, the benefits from an insurer like Max Bupa can be more comprehensive than other company for the same sum assured, Dr Marmion told the media at the launch of its new product 'Family First Health Insurance Plan'.
Earlier, speaking at a CII insurance summit, Mr Narayan said, "It is high time that the insurance industry also moves to offer portability so that the mediclaim and motor insurance policyholders can switch their service providers. We have initiated a debate on the idea of portability and we would be arriving at a conclusion very soon."
Mediclaim portability is a great initiative for policyholders, but the ground reality will be complicated for its implementation. One major concern about mediclaim portability is its impact on increasing losses for insurers. Moneylife had reported about mediclaim portability and its issues in its 'Insurance Trends' column. (Please see: http://www.moneylife.in/article/8497.html).
Segar Sampathkumar, deputy general manager, New India Assurance Co Ltd, said, "In order to have portability, products by different insurers have to be aligned. There is already an initiative to have a common product which could then be portable across companies. Portability is indeed needed, so that a customer, especially at an older age, is not stuck with the present insurer, even if the service is not agreeable. But at the same time, we have to ensure that sufficient safeguards are instituted in the model so that no insurer could deliberately drive away elder persons out of his books. I am sure these issues would be addressed and resolved in the near future."
Only time will tell whether mediclaim portability is implemented or remains just a wish, like mobile-telephony portability, which was actually far simpler to implement and yet has not been done so far.
Hyderabad: Mahindra Satyam (formerly Satyam Computer Services) today reported a consolidated loss of Rs124.60 crore for the year ended March 2010.
The company's net sales stood at Rs5,481 crore for the same period, Mahindra Satyam said.
This is the first audited financial results from the company after its founder and former chairman of Satyam Computer B Ramalinga Raju admitted to multi-crore accounting fraud in January last year.
Tech Mahindra took over reins of the company in April 2009 after the government-appointed panel cleared sale. It later rebranded fraud-hit company as Mahindra Satyam.
The Company Law Board had given exemption to Mahindra Satyam from publishing results for two financial years FY 2009 and FY 2010.
New Delhi: State Bank of India (SBI), the country's largest lender, today said it would soon take a call on raising deposit rates, a move in line with the Reserve Bank of India's (RBI) observation that lenders should attract depositors as they have various other options to park money, reports PTI.
"Soon," SBI chairman O P Bhatt said when asked how soon it would take a call on revising deposit rates.
The bank is also supposed to review base rate, the minimum lending rate below which bank cannot offer loans.
Currently, the base rate of the country's largest lender is pegged at 7.5%. In order to bring in more transparency, base rate was introduced as replacement for Benchmark Prime Lending Rate (BPLR) from 1 July 2010.
RBI in its first mid-quarterly review earlier this month had said, "One important consequence of negative real rates is that banks have seen a deceleration of deposit growth, as savers look for higher returns elsewhere. If bank credit is not to become a constraint to growth, real rates need to move in the direction of encouraging bank deposits."
One year fixed deposit earns about 7% while annual inflation for the month of August stood at 8.5%. So, depositors are getting a negative return of 1.5% or more on their fixed deposits.
Deposit growth on annual basis is 14.5% much lower than RBI's projection of 18%.
Last month SBI raised its benchmark lending rate by 50 basis points and deposit rates by up to 150 basis points.
While the increase in the benchmark prime lending rate to 12.25% made existing home, auto and corporate loans from the country's biggest lender dearer, the hike in deposit rates ensured better returns for deposit-holders.
SBI increased the interest rate by 150 basis points (1.5%) to 4% for term deposits of 15-45 days tenor. The deposit rate increase was the maximum in this slab.
For fixed deposits with a tenor between 181 days and less than one year, the new interest rate was 6% against 5.25%, while 555-day fixed deposits invited an interest rate of 7.25%.
The interest rate on term deposits of between three to five years' tenor went go up by 75 basis points to 7.25%, while interest on the 5-8 years' maturity slab increased by 25 bps to 7.50%.


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Redbox is America's destination for affordable and convenient new-release movie and video game rentals. About a million discs (and sometimes a whole lot more) are rented from our kiosks every single day. That adds up to more than 5 billion rentals since we launched in 2002 when My Big Fat Greek Wedding and Men in Black II were hot rentals.
Redbox is the best entertainment deal on the planet, and we should know – we're everywhere. We have more locations in the U.S. than Starbucks and McDonald's combined, so it's not hard to find us. You'll also find the lowest prices imaginable for today's biggest hits. With DVD rentals for just $1.50 a night, renting a new-release movie from Redbox is half the cost of a new-release cable movie rental, and we don't require a monthly subscription fee. Our latest innovation to bring entertainment to the masses – we're now selling previously-viewed movies and video games for amazingly low prices.
Redbox Fast Facts
- $1.50 a day for DVDs, $2 a day Blu-ray™ Discs and $3 a day for video games
- Earn free movie and game nights via Redbox Play Pass
- Rent a new-release cheaper than cable
- No monthly subscription required
- Rent and return anywhere at any of our more than 40,000 kiosks and counting
- Reserve online or on the Redbox app
Brief History
Redbox revolutionized the way Americans rent movies when it was founded in 2002 on the belief that consumers deserved a convenient way to rent new-release movies at a low nightly price.
Soon after testing began within McDonald's Ventures LLC, Redbox started counting its locations and rentals by the hundreds instead of the handfuls. During the peak period of installations, new kiosks appeared every hour, every day, 365 days a year to keep up with retailer interest and customer demand.
In 2010, Redbox rented its 1 billionth disc and also started renting Blu-ray™ Discs. Video games made their debut nationally in 2011.
Today, Redbox is located at some of the largest retailers nationwide, where Americans have rented more than 5 billion discs.
Let's do some math:
- When laid end-to-end, 5 billion discs could wrap around the world 15 times.
- 5 billion rentals adds up to more than 10 billion hours of movie-watching mania.
- New-release movie rentals used to cost a whole lot more a night, so our math tells us we've saved Americans about a gazillion dollars over the years.
The Redbox team works hard every day – in your local communities to uphold our promise to bring you a constantly updated selection of the newest hit movies and video games.


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High street general store Woolworths, which began trialing HD disc sales last autumn, now says it will stock only Blu-ray discs after sales in the format outsold rival HD DVD 10-to-one. Woolies' Steven McGunigel reasons: "Sales figures clearly show that the market is moving towards one format of high definition DVD. The main reason is the success of Sony's PlayStation 3 machine. Because it plays Blu-Ray discs, there are over three quarters of a million homes in the UK that can view the new high definition format. Switching to Blu-Ray only will provide one clear offer to customers in the format they want to watch high definition movies in."
Blu-ray is the wonder of Woolworths
January 29th, 2008 · No Comments
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The past few days have been painful for many.
The loss of Jeremy Clarkson seemed like it would tip millions of Top Gear fans over the edge, but even Jezza's fracas couldn't compare with the earth-shattering revelation on Wednesday that Zayn Malik had officially left One Direction.
i hate myself for being so blind zayn wasnt happy anymore but he stayed in the band because of the fans zayn is too good for this world— erika loves zayn (@spacekidlwt) March 27, 2015
I LOVE ZAYN AND THE BOYS SO MUCH . I WILL ALWAYS SUPPORT THEM NO MATTER WHAT. IM DONE.— we love you z (@whornystyles) March 27, 2015
how do you feel about zayn leaving? 'you seen titanic? sadder than that'— grace (@FookMashton) March 27, 2015
The 22-year-old had already left the band's world tour under a barrage of speculation and was signed off with stress before he released an official statement and crushed the hearts of millions of Directioners the world over.
We remember where we were when we heard that Geri had left the Spice Girls (a caravan in west Wales, if you're curious) so we understand the pain, but we aren't here to mourn the loss of the prettiest 1D member. Instead, we're here to pick his pockets and consider the contents of his bank account.
In 2014 the Sunday Times Rich List calculated the boys' combined earnings as £70m, with each of the lads pocketing £15m each. That gives Zayn – who's looking forward to being "normal" for a while – a lot of money to play with while he potters around the house and watches This Morning, like every other unemployed 22-year-old in the country.
How will he spend it, we wonder?
A fancy car
If we were Zayn we'd probably blow a few million on a ridiculous car to drive around his Berkshire neighbourhood. Maybe he should have a chat with a recently sacked expert to find out which…
Yes Zayn has seen more of the world than most of us ever will already, but he saw it while under the dictatorship of Simon Cowell, playing the part of a slightly moody dancing monkey. We think Zayn should buy a round-the-world ticket, get off the grid for a while and find himself. The poor wee lad skipped gap years and university after all, so he deserves a few months off to find spiritual calm in a temple in south-east Asia.
A recording studio
What better way to experiment with your artistry than by installing a recording studio in the privacy of your own home? We reckon Zayn is going to want to work with the freshest young producer when he makes his first solo cut (that's youth lingo for single) and rumours already abound that he's heading into the studio with producer Naughty Boy. This way he can keep any juicy collabs on the down low.
An island
If all the post-1D attention gets too much for the sensitive soul he could escape to his own private island – this one in Belize looks a steal at $99,000.
What do you think Zayn should do next? Tell us on Facebook and Twitter
News in brief
The Treasury and Gocompare.com launched a new current account comparison service called midata.
Green power generated in Norway is coming to the UK via the world's longest sub-sea electricity interconnector and will soon be powering our homes.
Identity theft is most likely to happen to a 46-year-old man, according a report from fraud prevention service Cifas. Recorded fraud was up by 25% last year compared with 2013.
On Covered Mag this week
Emily Bater meets four happy people who switched their current accounts
Get busy on two wheels with our five things to do with your motorbike this Easter
Abbie Laughton-Coles shows you the world's most popular countries from a different perspective
Join us next week for another thrilling instalment of the Money Shot. In the meantime, email us your letters
Main image: Sarah Hiscoe


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Tiffany Genealogy from 1577 on
Best site for this information is www.FamilySearch.org. - LDS (Mormon) Church site. My mother was a Tiffany. Her ancestors joined the Mormons in the early days of Joseph Smith and followed the Mormons from Newfield, NY-Eaton, Ohio-Litchfield, Ohio-Nauvoo, Illinois-Garden Grove, Iowa-Ft. Laramie, Wyoming-finally to Salt Lake City, Utah-Provo, Utah-Salem, Utah settling there in 1859 (it was originally known as 'Pond Town'). Email me if you have questions.


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It's Safe Now, America. Jessica Alba's Here.
Man she lost her looks over the years
She hasn't lost her looks. She looked better because of all the professional makeup, airbrushing, and digital enhancements.
'His or her arrival'? Apaprently the miracle of birth is no longer exciting after the first child, so she's spicing up the second pregnancy by not learning the fetus's gender. Artificial injection of excitement for the win!
At least the oldest guy of the Senate thinks I'm hot.


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High on Fire Begin Work on "Powerfully Supernatural" New Album; Song Titles Revealed
High on Fire have entered the studio to begin tracking their as-yet-untitled new album. The follow-up to 2010's Snakes for the Divine is being recorded at Salem Massachusetts' GodCity Studios with producer, and Converge guitarist, Kurt Ballou.
"We are really stoked about recording this album," bassist Jeff Matz said. "The new songs are turning out absolutely punishing; there are some seriously sledgehammer riffs on this one! Working with Kurt has been awesome as well. He's super easy to work with and is full of good ideas. The sounds that the guy gets are ridiculous and raw as f*ck but also clear and HUGE. I think this album will capture the essence of the band really well. It's still early in the process, but so far it's sounding amazing."
The new record is said to be "direct, eye-opening, and powerfully supernatural." Some tentative song titles have also been revealed for the new record; they are "Serums of Liao," "Madness of an Architect," "De Vermis Mysteriis," "Spiritual Rites," and "Warhorn."
Next Article


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Discussion in 'Off-topic Zone' started by MichaelWinicki, Nov 11, 2004.
or it could be a hardcore cowboys fan with lots of free time
JR is not only married... he is whipped... I work with the poor guy...
Post of the day.
Trick, be glad he didn't call you a gentleman and a scholar.
Thank ya... thank ya very much..
I rarely get accused of such... (even though I am both)...
Congrats to you both on passing 4K. I never notice how many posts I have until someone brings it up.
I need to shut up.
Wow. Fessing up. That took stones.
Hey Hos, I think you're pretty close to being acused of being a G and a S yourself... so watch out!
Even if accused of it I won't admit to it. I deny everything. Teflon baby.
To my friend Michael Winicki,
Your early morning news threads are always appreciated and the perfect start to my day; your sense of humor is often, delightful.
I often poke fun at you because of where you live. Ya know, I once read that we only tease those we truly respect. There's a reason why I only read it once...because it's simply not true. You're a Canadian hick who lives in the middle of an oversized Amana freezer called "Olean". Kinda hard to respect that.
Anyway, all kidding aside....I think, and I am sure there are several others who would agree, you are done a disservice if we simply honor you for your 4000 posts. It's quality, not quantity, that matters MW. And I can say, from the bottom of my heart, sifting through those 4000 posts to find the dozen or so good ones has truly been a waste of everyone's time.
*teary eyed*
Congrats MW.
you are both?? hahahahahahahahahahahahahahahahahahahahahahahahahahahahahahahahahahahahahahahahahahahahahahahahahahahahahahahahahahahahahahahahahahahahahahahahahahahahahahahahahahahahahahahahahahaha
oh stop .. it hurts.. hahahahahahahahahahahahahahahahahahahahahahahahahahahahahahahahahahahahahahahahahahahahahahahahahahahahahahahahahahahahahahahahahahahahahahahahahahahahahahahahahahahahahahahahahahahahahahahahahahahahahahahahahahahahahahahahahahahahahahahahahahahahahahahahahahahahahahahahahahahahahahahahahahahahahahahahahahahaha
Just kidding...
"I love you man!"
And heck I thought it was the aluminum foil hat you wear on your head...
Silly me!
It's duct tape.
Ah, from a distance gray duct tape sorta looks like aluminum foil.
Eye check...
How many fingers am I holding up?
And I thought your 4000th post would be something meaningful, like lamenting the Castle's passing of years ago (best prime rib ever) or expounding upon the virtues of the Library.
****** man, real men only care about the Cowboys, alcohol and great food.
Get with the program.


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PlanNext - Project Schedule & Management, Gantt Charts
vendredi 01 juillet 2016 06h46
About PlanNext - Project Schedule & Management, Gantt Charts
PLAN PROJECTS & COLLABORATE WITH YOUR TEAM. Changes are automatically saved and updated within seconds to your whole team, without having to export / import or email a project file.
FREE Trail & FREE to invited team members. Start getting things done today!
PlanNext can be used on your iPhone, iPad, iPad Mini, iPod Touch, and on your DESKTOP BROWSER at the PlanNext website.
- Drag n Drop Functionality
- Filter By Resource
- Add and Edit "Floating" Notes
- Templates Provided (or create your own!)
- Assign User Access Privileges
Please take a moment to rate PlanNext and share it with a friend.
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Miami May Be Number Two for Startups, but Most Stay (Very) Small Businesses
Photo via Pexels CC2.0
Tons of Miamians start their own businesses. Many perhaps dream of running worldwide empires out of corner offices in Brickell office buildings. But it turns out that few of those would-be empires ever grow to employ more than five people.
Back in August, the Kauffman Index crowned Miami America's second hottest metro for startup activity based on the sheer number of small business started here every year, but today the Index dropped a second component: it's Growth Entrepreneurship report. Out of the 40 metro areas analyzed, Miami came in second to last in small-business growth.
Though "startup" is a buzzword most associated with the tech industry, Kauffman counts any company less than five years old that employs its owner and at least one other person as an employee. That means everything from a group of techies trying to come up with the next world-disrupting app to your aunt starting a cupcake baking business are counted as startups.
Miami has a lot of those startups. In its August report, Kauffman found that there were 247.6 startups in town for every 100,000 residents, the highest density of any metro in America. They just don't have a tendency to grow very much.
The analysis found that the rate of startup growth in the area was just 39.46 percent. That means the average startup started out with 4.8 employees, but after five years of operation only grows to 6.7 employees.
Kauffman keeps data all the way back to 1983, and the startup growth rate at that time in Miami was 84.38 percent. The rate peaked in 1988 at 97.46 percent but has been tumbling down ever since. That's not true in all cities. Washington, D.C., the Index's crowning champ of startup growth, has a growth rate of 116.85 percent.
The rate of startup growth in Miami is well below average.
via Kauffman Index
The chances of a startup growing into a super-successful company are even smaller. Just 0.81 percent of Miami startups grow to employ more than 50 people in their first ten years of operation. In 1987, that share was 2.27 percent.
The percentage of startups that grow into mid-sized companies has been declining in Miami for decades.
via Kauffman Index
For context, we might want to look at the August report's "opportunity index." It measures the percentage of entrepreneurs who left steady jobs of one sort or another to start their own businesses. The rate was 73.9 percent, which was the second lowest of any metro in that report's top ten.
That means 26.1 percent of small businesses in the area are started by those who are coming directly out of unemployment.
Get the ICYMI: Today's Top Stories Newsletter Our daily newsletter delivers quick clicks to keep you in the know
Catch up on the day's news and stay informed with our daily digest of the most popular news, music, food and arts stories in Miami, delivered to your inbox Monday through Friday.
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SARASOTA, Fla. -- Final preparations are under way on the Suncoast as the 2014 Modern Pentathlon World Cup Finals is set to kick off Friday. This is the first time the event will be held in the United States in 40 years.
The winners go to the Olympics.
Competition starts June 6. Women compete Friday, men Saturday. Mixed relays are Sunday. And not only does the pentathlon give Suncoast residents a chance to watch some of the best athletes in the world compete at the peak of their game, it also brings a lot of visitors to the Suncoast and is a real boost to the economy.
ABC 7's Ray Collins will have a preview of the events tonight on ABC 7 News at 5.


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Type 1 Diabetes
In 2015, it was estimated that 415 million people around the world have diabetes. Of this total, about five percent of this population are Type 1. The primary cause of Type 1 is an inflammatory response from an autoimmune reaction from antibodies being made against the beta cells. The beta cells store and release insulin into the body as needed.
There are also certain viruses that seem to attack and destroy the pancreatic beta cells directly, rather than through an autoimmune reaction. Mumps, prior to the onset of diabetes, was found in 42.5 percent of the subjects versus 12.5 percent in the control group.
Additionally, a significant correlation between antibodies to cow's milk protein, and Insulin Dependent Diabetes Mellitus. Some studies have found somewhere between 75 to 90 percent of the cases of Type-1's have antibodies against the beta cells of the pancreas. Cow's milk seems to be strongly linked to the onset of Type 1.
Type 1's need insulin either continually infused through an insulin pump or by injections. Balancing blood sugar levels involves evaluating blood sugar readings, carbs on the menu, insulin already on board and exercise. Stress and illness can also influence blood sugar levels, generally making them higher.
Incorrect insulin injection estimates can often result in hyperglycemia, when the blood sugar is too high, and hypoglycemia, when the blood sugar drops to low. In the event that either one of these events happens, medical attention is often necessary.
Because of these reasons, and since the Tree of Life Center is not a medical facility, previously Type 1 diabetics have not been accepted into programs. Recently a on-site Type 1 Educational Program consisting of the Zero Point Intensive, Conscious Eating and Expanding Culinary joy, are now open to Type 1's.
Type 1 Diabetes Educational Courses:
Zero Point Intensive – led by Dr. Cousens at the Tree of Life Center US is a powerful technique used to break the mind of toxic thought patterns. It is a tool that enables you to free yourself of old habits, addictions, and cycles within your life that may have been contributing to or holding you back from progressing spiritually. During this course, learn how to enter a state where consciousness controls the mind rather than the mind controlling consciousness. The Zero Point Process allows the opening of the mind, allowing one to live freely in the world without expectations or hopes, and is considered a complete emotional and mental detoxification.
Conscious Eating – A Tree of Life Café Chef will teach you about the important tools in a raw food kitchen, and share techniques that help you put together meals simply at home. You will get a recipe book, Q & A time and hands on training to help make your raw food diet a success!
Expanding Culinary Joy – This course will build your raw food skills and recipe book even more. Expand skills and knowledge about raw food and its preparation, you'll feel comfortable enough to create a tasty, nutritious meal for family and friends.
NOTE: Type 1 Diabetics attending the Zero Point, Conscious Eating and/or Expanding Culinary Joy programs will be responsible to regulate their own insulin and blood sugars accordingly. In general, the need for insulin may go down 25 to 30% on our live food moderate low carb cuisine. We are not an emergency medical facility and we do not have resources to take care of hypoglycemic shock or diabetic ketoacidosis. If this occurs an ambulance will be called and you will be responsible for the charges. Insulin is not available on site, but meters are available to purchase.
To find out more, please call: 520-233-7010


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Want to help your child with their future career? Make sure they take part in the largest national survey of career ambitions – they could also win £300!(1 Post)
careersmum2 Tue 03-Dec-13 12:56:03
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