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The role of copeptin as a diagnostic and prognostic biomarker for risk stratification in the emergency department
The hypothalamic-pituitary-adrenal axis is activated in response to stress. One of the activated hypothalamic hormones is arginine vasopressin, a hormone involved in hemodynamics and osmoregulation. Copeptin, the C-terminal part of the arginine vasopressin precursor peptide, is a sensitive and stable surrogate marker for arginine vasopressin release. Measurement of copeptin levels has been shown to be useful in a variety of clinical scenarios, particularly as a prognostic marker in patients with acute diseases such as lower respiratory tract infection, heart disease and stroke. The measurement of copeptin levels may provide crucial information for risk stratification in a variety of clinical situations. As such, the emergency department appears to be the ideal setting for its potential use. This review summarizes the recent progress towards determining the prognostic and diagnostic value of copeptin in the emergency department.
Risk stratification is a core task in emergency medicine. Novel biomarkers such as pro-calcitonin and copeptin have emerged to assist clinicians with decision-making. Elevated pro-calcitonin levels, for example, might help to decide whether administration of antibiotics in lower respiratory tract infections is necessary
Arginine vasopressin (AVP), also known as antidiuretic hormone, is one of the key hormones of the hypothalamic-pituitary-adrenal (HPA) axis. Copeptin, a peptide of 39 amino acids, is the C-terminal part of pro-AVP and is released together with AVP during processing of the precursor peptide (see Figure
Figure 1
Cartoon of the 164-amino acid peptide precursor, preprovasopressin
Cartoon of the 164-amino acid peptide precursor, preprovasopressin. Shows the signal sequence (white), AVP (dark green), neurophysin II (pale green) and copeptin (light green). Copeptin (CT-proAVP) is the C-terminal part of proAVP. Numbers indicate amino acids of the human protein. AVP: arginine vasopressin; CT-proAVP: C-terminal proAVP; signal: signal peptide.
Figure 2
Synthesis and release of AVP and copeptin in hypothalamus and pituitary
Synthesis and release of AVP and copeptin in hypothalamus and pituitary. Pro-AVP is processed in the hypothalamus, followed by two distinct release-mechanisms for the anterior and posterior pituitary. During stress, a drop in blood pressure, or a change in osmotic pressure, AVP is released into the circulation. ACTH: adrenocorticotropic hormone; AVP: arginine vasopressin.
In contrast to AVP and cortisol, copeptin is stable both in serum and plasma at room temperature and can be easily measured
This mini review outlines the potential prognostic and diagnostic use of copeptin in the ED in the context of a number of different possible clinical conditions and summarizes the recent progress made in this field.
Effects of copeptin and AVP in the circulation
The physiologic function of AVP is threefold. When released into the circulation, AVP mediates arteriolar vasoconstriction via the V1-receptor and exhibits an antidiuretic effect in the kidneys via the V2-receptor
Copeptin in acute myocardial infarction and heart failure
Early and safe rule-out of myocardial infarction (MI) is crucial in the ED. Reichlin
At present, there is confusion on the nomenclature and clinical use of these assays
In several studies, copeptin has been reported to be a useful biomarker in patients with chronic heart failure. High levels of copeptin predicted poor long-term prognosis in patients with chronic heart failure
When copeptin was measured in 980 patients who had experienced an acute MI, it was found to be elevated in patients who died or were readmitted with heart failure, compared with survivors. Copeptin and N-terminal proBNP were independent predictors of death or heart failure at 60 days, helping to stratify patients into low-, intermediate- or high-risk groups
The clinical evidence in this field is increasing rapidly. A recent study of patients treated in an outpatient clinic for chronic stable heart failure showed that copeptin and high-sensitivity cardiac troponin T (hs-cTnT) levels, both single and combined, are powerful predictors of death and hospitalization. This suggests that simultaneous assessment of myocardial damage and the activated vasopressin system, through single measurement of hs-cTnT and copeptin levels, might be of prognostic relevance
Copeptin may have not only short term prognostic relevance, but also identify patients at higher long-term risk. Increased copeptin concentrations in elderly patients with symptoms of heart failure were associated with an increased risk of all-cause mortality after a lengthy median follow-up of 13 years
Finally, a secondary analysis from the Biomarkers in Acute Heart Failure (BACH) study looked at the interaction of copeptin and sodium concentrations. Whilst it is well known that low serum sodium is an indicator of increased mortality in patients with heart failure, no studies examined if and how the vasopressinergic system was activated. The authors of the BACH study now report significantly increased 90-day mortality, readmissions and ED visits in patients with hyponatremia, especially in those with elevated copeptin. Patients with hyponatremia and low copeptin had a lower risk. Copeptin was highly prognostic for 90-day adverse events in acute heart failure patients, adding prognostic value to clinical predictors, serum sodium and natriuretic peptides. This report is of particular interest in the light of ongoing discussions on the potential value of vasopressin receptor antagonists (such as tolvaptan) for patients with heart failure, as elevated copeptin may identify those patients with an activated AVP system most likely to benefit from AVP antagonists
Copeptin in hyponatremia and diabetes insipidus
Hyponatremia is common in the ED, but the diagnostic approach is often challenging
Copeptin as a prognostic marker
Besides the clinical indications mentioned so far, the role of copeptin as a prognostic biomarker was also examined in a variety of other indications, such as acute exacerbations of chronic obstructive pulmonary disease
Table 1
Overview of studies investigating the use of copeptin in different clinical settings.
Clinical scenario
Number of patients
Copeptin levels > 40 pmol/L associated with prolonged hospital stay and long-term clinical failure (death or rehospitalization for AECOPD up to six months after inclusion).
Copeptin levels increased with increasing severity of LRTI, as classified by the Pneumonia Severity Index
- predictive of mortality (AUC 0.75)
- copeptin levels in survivors 24.3 pmol/L (normal: 10.8 to 43.8 pmol/L), versus 70.0 pmol/L (normal: 28.8 to 149 pmol/L) in non-survivors
- optimal threshold of copeptin, 53 pmol/L; sensitivity to correctly predict mortality, 58% with a specificity of 80%; LR+ 3.0, LR- 0.5
Hemorrhagic and septic shock
Copeptin levels increased with disease severity from systemic inflammatory response syndrome to sepsis and severe sepsis to septic shock
- copeptin levels in non-survivors, 171.5 pmol/L versus survivors, 86.8 pmol/L,
- predictive of mortality (AUC 0.75)
- optimal prognostic accuracy of copeptin at 96 pmol/L; sensitivity, 61.5%, specificity 83.8%
Acute ischemic stroke
- associated with severity of stroke and lesion size
- predicts functional outcome (AUC 0.73) and mortality (AUC 0.82) after three months
Cerebrovascular re-event after transient ischemic attack within 90 days
- AUC for copeptin to predict re-event within 90 days, 0.73.
- at cutoff of 9.0 pmol/L for copeptin; sensitivity, 80%, specificity, 76%
One-year outcome in patients with acute stroke
One-year follow-up on ED patients
341 of 362
Copeptin predicts
- one-year mortality after stroke (AUC 0.74)
- functional outcome (AUC 0.72)
Acute spontaneous intracerebral hemorrhage
Copeptin predicts
- 30-day mortality (AUC 0.88), comparable with that of GCS (AUC 0.82)
- 90-day functional outcome (AUC 0.68)
Traumatic brain injury
- predicts one-month mortality (AUC 0.874), similar to that of GCS
- copeptin levels > 451.8 pg/mL; sensitivity, 88.5%, specificity, 75%, in prediction of one-month mortality
AECOPD: acute exacerbation of chronic obstructive pulmonary disease; AUC: area under the curve; ED: emergency department; GCS: Glasgow Coma Scale; ICU: intensive care unit; LR-: negative likelihood ratio; LR+: positive likelihood ratio.
Copeptin in elderly ED patients presenting with non-specific complaints
Older patients in the ED are at risk of adverse health outcomes
Copeptin and other biomarkers
In the ED, copeptin is in competition with other novel biomarkers that are also investigated for their potential use as prognosticators. Apart from established cardiac markers such as BNP, NT-proBNP and derivates of atrial natriuretic peptide
Limitations of copeptin
As with most biomarkers there are certain confounding factors for the interpretation of copeptin levels. Copeptin levels were found to be higher in the male volunteers compared with female. Especially in men, there is a strong relationship between copeptin and decreased glomerular filtration rate, probably due to decreased renal copeptin clearance
AVP is a substantial part of the endocrine stress response, resulting in ACTH and cortisol release. The trigger for the rapid release of AVP and copeptin in acute disease is not yet clear. Possibly, the body responds to acute and life-threatening diseases by immediate AVP and copeptin release. Copeptin as a biomarker appears to reflect the individual stress level
In the ED, copeptin may be a clinically useful non-specific prognostic marker reflecting disease severity in patients with a wide array of diseases, such as lower respiratory tract infections, heart failure and stroke. Copeptin might assist with risk stratification, resource allocation and disposition planning. However, future studies are needed to evaluate ideal cut-off levels in these clinical scenarios. Additionally, intervention trials are needed to show that determination of copeptin levels in the emergency setting improves patient care.
The concept of a readily available biomarker with the ability to improve prognostic accuracy of known risk stratification tools, such as risk scores, is attractive. Is copeptin, perhaps, the long awaited biomarker that discerns 'sick' from 'not sick'?
Competing interests
BRAHMS Biomarkers, part of ThermoFisher Scientific, the manufacturer of the copeptin-assay, provided measurements for CHN and RB's study on geriatric emergency patients. No funding was obtained from commercial sources.
Authors' contributions
CHN, RB and NGM were involved in drafting and editing the manuscript. All authors read and approved the final manuscript.
Thanks to Karen Delport-Lehnen MD for helpful discussions.
Effect of procalcitonin-guided treatment on antibiotic use and outcome in lower respiratory tract infections: cluster-randomised, single-blinded intervention trial
Effect of procalcitonin-based guidelines vs standard guidelines on antibiotic use in lower respiratory tract infections: the ProHOSP randomized controlled trial
Nucleotide sequence of cloned cDNA encoding bovine arginine vasopressin-neurophysin II precursor
Corticotropin releasing activity of the new CRF is potentiated several times by vasopressin
Modulation of stress-induced ACTH release by corticotropin-releasing factor, catecholamines and vasopressin
Interaction of corticotropin-releasing factor and arginine vasopressin on adrenocorticotropin secretion
Augmentation of the response to CRF in man: relative contributions of endogenous angiotensin and vasopressin
The hypothalamic-pituitary-adrenal axis in critical illness
Free and total cortisol levels as predictors of severity and outcome in community-acquired pneumonia
Copeptin, a stable peptide derived from the vasopressin precursor, correlates with the individual stress level
Copeptin, a stable peptide derived from the vasopressin precursor, is elevated in serum of sepsis patients
Assay for the measurement of copeptin, a stable peptide derived from the precursor of vasopressin
Vasopressin receptors
The human V3 pituitary vasopressin receptor: ligand binding profile and density-dependent signaling pathways
Copeptin, a stable peptide of the arginine vasopressin precursor, is elevated in hemorrhagic and septic shock
Incremental value of copeptin for rapid rule out of acute myocardial infarction
Copeptin improves early diagnosis of acute myocardial infarction
Early diagnosis of myocardial infarction with sensitive cardiac troponin assays
Sensitive troponin I assay in early diagnosis of acute myocardial infarction
High-sensitivity cardiac troponin: hype, help, and reality
Combined testing of high-sensitivity troponin T and copeptin on presentation at prespecified cutoffs improves rapid rule-out of non-ST-segment elevation myocardial infarction
Copeptin, a fragment of the vasopressin precursor, as a novel predictor of outcome in heart failure
Comparative evaluation of B-type natriuretic peptide, mid-regional pro-A-type natriuretic peptide, mid-regional pro-adrenomedullin, and copeptin to predict 1-year mortality in patients with acute destabilized heart failure
C-terminal provasopressin (copeptin) as a novel and prognostic marker in acute myocardial infarction: Leicester Acute Myocardial Infarction Peptide (LAMP) study
C-terminal provasopressin (copeptin) is a strong prognostic marker in patients with heart failure after an acute myocardial infarction: results from the OPTIMAAL study
Complementary role of copeptin and high-sensitivity troponin in predicting outcome in patients with stable chronic heart failure
Association of copeptin and N-terminal proBNP concentrations with risk of cardiovascular death in older patients with symptoms of heart failure
Increased 90-Day mortality in acute heart failure patients with elevated copeptin: secondary results from the Biomarkers in Acute Heart Failure (BACH) Study
Hyponatremia in critically ill patients
Copeptin in the differential diagnosis of hyponatremia
Copeptin in the differential diagnosis of the polydipsia-polyuria syndrome--revisiting the direct and indirect water deprivation tests
Anterior and posterior pituitary function testing with simultaneous insulin tolerance test and a novel copeptin assay
The use of copeptin, the stable peptide of the vasopressin precursor, in the differential diagnosis of sodium imbalance in patients with acute diseases
Copeptin, C-reactive protein, and procalcitonin as prognostic biomarkers in acute exacerbation of COPD
Circulating levels of copeptin, a novel biomarker, in lower respiratory tract infections
Stress hormones predict cerebrovascular re-events after transient ischemic attacks
Prognostic value of copeptin: one-year outcome in patients with acute stroke
Copeptin is associated with mortality in patients with traumatic brain injury
Older adults in the emergency department: a systematic review of patterns of use, adverse outcomes, and effectiveness of interventions
Patients presenting to the emergency department with non-specific complaints: the Basel Non-specific Complaints (BANC) study
Copeptin and peroxiredoxin-4 independently predict mortality in patients with nonspecific complaints presenting to the emergency department
Weakness as presenting symptom in the emergency department
Mid-region pro-hormone markers for diagnosis and prognosis in acute dyspnea: results from the BACH (Biomarkers in Acute Heart Failure) trial
Short-term mortality risk in emergency department acute heart failure
Measurement of the interleukin family member ST2 in patients with acute dyspnea: results from the PRIDE (Pro-Brain Natriuretic Peptide Investigation of Dyspnea in the Emergency Department) study
Prognostic value of growth-differentiation factor-15 in patients with non-ST-elevation acute coronary syndrome
Gender and renal function influence plasma levels of copeptin in healthy individuals
The influence of corticosteroids on the release of novel biomarkers in human endotoxemia
Copeptin: a novel, independent prognostic marker in patients with ischemic stroke
Copeptin is associated with mortality and outcome in patients with acute intracerebral hemorrhage
Pre-publication history
The pre-publication history for this paper can be accessed here:


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Samsung Buys 5 Percent of Stylus Maker Wacom
Tiffany Kaiser
January 31, 2013 8:56 PM
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(Source: static.geekbeat.tv)
Samsung's 5 percent cost $58.2 million USD
Samsung has bought 5 percent of Wacom, which is likely an attempt to equip more of its tablets and smartphones with the high-quality stylus'.
Wacom is a company that specializes in interactive pen displays and digital drawing tablets. Samsung's 5 percent cost $58.2 million USD, allowing it to couple the stylus' with devices like its Galaxy Note line.
"It is becoming increasingly important to form close relationships with manufacturers of mobile information terminals, particularly smartphones and tablets, and to bring new products to market in a timely manner," said Wacom. "With regard to digital pens for smartphones in particular, Wacom's sales to
Samsung Electronics
have increased in recent years. Wacom digital pens are used in Samsung Electronics' Galaxy Note smart phone, which is sold in 99 countries around the globe including in North America, Europe, Japan, China and India. Wacom expects the inclusion of its digital pens in Samsung Electronics' smartphones and tablets to lead to the expansion of the user base of its products."
While stylus' have largely become a thing of the past (due to the amount of touch devices available), Wacom doesn't make any ordinary stylus -- they're pressure sensitive so that they can be used for drawing and other work.
Samsung is a great hardware manufacturer to partner with too, since its Android-powered smartphones are popular (Samsung sold about 60 million smartphones in Q4 2012 while Apple only sold 47.8 million iPhones) and its tablet market share is growing significantly (
Samsung represented
15.1 percent of the U.S. tablet market share
as of Q4 2012, and had a 263 percent year-on-year growth).
Phone Arena
"Then they pop up and say 'Hello, surprise! Give us your money or we will shut you down!' Screw them. Seriously, screw them. You can quote me on that." -- Newegg Chief Legal Officer Lee Cheng referencing patent trolls
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Architecture Links, Global Listings for Architects, Property, Design, Buildings
Architecture Links : Built Environment Information
Architectural Information – Building Centres + Architect Practices
Architectural Links
This site has one of the most comprehensive Architecture Links pages for competitions : Architecture Competitions
Key World Architects
We list below what we feel are the most important and talked about design studios in the world currently, of course there will be some that maybe should have been included, but this quick attempt at a list might prove useful. We have a page elsewhere on the site that includes a longer list of key contemporary architects – such as Tadao Ando and Toyo Ito:
Santiago Calatrava
David Chipperfield
Foster + Partners
Frank Gehry
Zaha Hadid
Daniel Libeskind
Richard Meier
Richard Rogers
A key architect from the past, an innovator:
Rennie Mackintosh
We welcome architecture-related links such as interior products, building elements, materials and property links.
Key Building Projects on the site
Burj Khalifa, Dubai, UAE
photo from Emaar
Barcelona Pavilion, Barcelona, Catalonia, Spain
Empire State Building, New York City, NY, USA
Rockefeller Center, New York City, NY, USA
Birds Nest Beijing, China
photo © Arup_Ben McMillan
Abu Dhabi Building, UAE
Dubai Palm Island, UAE
Singapore Tower, singapore
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photo © Hélène Binet
Comments for the Architecture Links page welcome
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Medical grade all in one computers that are 60601-1 certified with antimicrobial housing.
Made with military grade components, fanless, IP65 sealed, rugged & tough with RS232 ports.
VESA / wall mountable enterprise all in one PCs designed specifically to meet the needs of business.
Tough & reliable, IP65 sealed, 60601-1 certified with antimicrobial housing and integrated barcode scanner.
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This rugged medical tablet has integrated barcode scanner, RFID, fingerprint reader and many other features.
Two hot swap batteries means this tablet can go all day without being plugged in.Learn More
Our new 24" medical cart computer with three hot swap batteries powers your peripherals, including printers & barcode scanners.
Just plug directly into the computer.
Ideal for non-powered carts.Learn More
We love how flush against the wall this computer fits. It fits perfectly well in the recessed wall enclosure where we previously had the iPads.
MC, IT Technical Engineer, A.D. HIGH TECH INC.


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By Jeff Zillgitt, USA TODAY
In five of the Lakeland (Fla.) Dreadnaughts' 14 victories, including two 5A playoff games, they scored the winning touchdown with less than six minutes left in the fourth quarter.
No. 6 Lakeland scored the go-ahead touchdown with 4:04 left in the fourth quarter in the second round of the playoffs against Osceola (Kissimmee) and scored with 5:17 left in the semifinals last week vs. Pine Forest.
"This team has showed real resilience — hanging in there and playing tough when it counts," Lakeland coach George Castle said. "We've just been able to make the big play at the end. It's just our kids' will to win."
That will to win will be tested tonight against No. 1 St. Thomas Aquinas (Fort Lauderdale) in the championship game. Castle does not want to be trailing late against St. Thomas Aquinas (14-0), the defending 5A champ.
"St. Thomas is maybe the best team I've ever seen," Castle said.
Castle has seen his share. Since 1979, he is 50-15 in the playoffs at Lakeland, including 6-0 in state title games. And he has seen his share of St. Thomas Aquinas teams.
Of Castle's six state titles, he defeated Aquinas in four of those games — in 1996, 2004, 2005 and 2006.
The schools have combined to win the past four 5A titles, and it will be five in a row after tonight.
"We're facing a different kind of team this week," Castle said. "They're really explosive offensively. Defensively, they've got great corners that allow them to play eight men in the box and shut your run (game) down."
Aquinas has pummeled opponents, outscoring them on average 45.6 to 7.9. That's not a surprise considering the talent:
Receiver Duron Carter, the son of former NFL receiver Cris Carter, has committed to Ohio State; tight end Gabe Holmes (Purdue), offensive lineman Jordan Cowart (Notre Dame), linebacker Conor O'Neill (Wisconsin) and punter Ben Turk (Notre Dame) are part of a talented senior class.
There are major college prospects in the junior class, too: running backs Giovanni Bernard and James White and offensive lineman Brandon Linder.
Just two opponents have scored more than 10 points vs. the Raiders. One was Elder (Cincinnati) in the first game of the season in the Kirk Herbstreit Varsity Football Series. Elder took a 10-0 lead in the first quarter, but Aquinas scored 28 unanswered points en route to a 35-24 victory.
"That really helped us get going," Aquinas coach George Smith said.
O'Neill goes back to the 2007 season to find a pivotal game, the Raiders' loss to Deerfield Beach. They haven't lost since.
"The character of our team changed," O'Neill said. "We had to change our mind-set. We weren't invincible. We're more of a team."
Guidelines: You share in the USA TODAY community, so please keep your comments smart and civil. Don't attack other readers personally, and keep your language decent. Use the "Report Abuse" button to make a difference. Read more.


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Razer Serval Android gaming controller lands on Google Play store
One of the biggest challenges to playing some Android games on your mobile device is that on-screen controls or tilt controls often leave a lot to be desired. Thankfully, there are bunches of different gaming controllers that will connect to your Android device and allow you to use a controller for your favorite games. A new Bluetooth Android gaming controller has landed on the Google Play store from Razer called the Serval.


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Clinical Trials in Diabetes
Clinical trials are done basically to prevent disease, to develop new and better treatments, or to find a potential cure. A clinical trial is a way to carefully test a new drug or device in patients before it is approved by the FDA to be used in the general public. Clinical trials are an important step in our being able to have new treatments for diabetes and other conditions. American Diabetes Association also provides support in the clinical trials of Diabetes. They different trials for different type of Diabetes is being run here names as TrialNet is basically to delay and reverse the process of Type 1 Diabetes, GRADE is a comparative effectiveness study looking at what medications work best at lowering blood glucose levels in patients who are newly diagnosed with diabetes, RISE (Restoring Insulin Secretion study), D2D (Vitamin D and type 2 diabetes), Accelerating medicines partnership (AMP) and FNIH biomarker Consortium. Many other associations also do diabetic trials for management of Diabetes i.e. Diabetes UK Organization etc.


text: Opportunity Home About Us Opportunity The Atlantic Ocean is a magnificent resource of untapped power to generate offshore wind energy. The next frontier in domestic energy production, offshore wind is a unique opportunity to create an entirely new industry and thousands of jobs by tapping into this clean, stable-priced resource and harnessing it for energy. A resource which, by the way, has enough potential along the U.S. East Coast to meet the electricity demands of at least one-third of the United States – or, enough to power the entire East Coast. This emerging industry will create thousands of jobs and improve consumer access to clean energy sources. The Atlantic Wind Connection backbone transmission project is an essential foundation to this new industry. Designed to accelerate offshore wind development, the project is led by well-established independent transmission company Trans-Elect and sponsored by Bregal Energy, Google, Marubeni Corporation, and Elia. The Mid-Atlantic region alone offers more than 60,000 megawatts of offshore wind potential in the relatively shallow waters of the outer continental shelf, ten to twelve miles off the coast. That's enough to power more than 50 million homes. Today, voters in the Mid-Atlantic support offshore wind more than ever. In fact, public opinion polling of area voters found that 79 percent of Mid-Atlantic respondents support the development of wind power and a strong majority are willing to pay extra to get this clean energy. Jobs and Growth Offshore wind presents the unique opportunity to create an entirely brand new industry in the United States. With over 8,000 components in a modern wind turbine, many offshore wind turbine components can be manufactured here in the United States. Today, about 2/3 of the components in U.S. land-based wind turbines are manufactured domestically. There are significant opportunities for U.S. manufacturers to play a similarly substantial role in the offshore wind supply chain. Local sourcing is preferred for towers, castings, forging services, nacelle covers and blades to reduce transportation costs, decrease currency risk, and increase just-in-time turbine availability, product quality and service. As turbines become larger, few suppliers are equipped to produce the unique components and the size makes the components expensive and difficult to transport. The offshore wind industry's development will open up new markets for local suppliers. According to a 2011 study of the economic benefits of offshore wind, commissioned by Atlantic Wind Connection, the employment and GDP impact can be immense. The study was conducted by IHS Global Insight, a leading global analytics firm. IHS analyzed the economic benefits of building 7,700MW of offshore wind farms and the AWC offshore transmission line along the Mid-Atlantic. They found that a Mid-Atlantic build-out can create approximately 310,000 job-years of work (about 31,000 workers) in the US. There will be direct employment growth primarily in the construction of and operations/maintenance of the wind farms and transmission system, but that there will also be significant opportunities to develop the local manufacturing supply chain. Thus, a Mid-Atlantic build-out can create: 80,000+ job years from direct construction and manufacturing, 98,000+ job years from indirect employment at suppliers of equipment and services, and, 130,000+ job years induced as wages flow through the economy. All the additional economic activity would increase the GDP by $33 billion and increase Federal, state and local taxes by $7.5 billion. Lowering Energy Prices Decades ago, land-based wind was considered high cost. America, however, committed to lead in land-based wind and over time we learned to build turbines better, larger, and at a lower cost. Today, not only are thousands employed in land-based wind, but the cost of land-based wind energy production has decreased close to the level of fossil-fueled energy. Land-based wind is now a viable, stable-priced, clean energy resource that contributes to our energy security. A similar success is possible with offshore wind. Today it is comparable in cost to solar energy. However, as offshore wind technology evolves, with larger, more efficient machines, and as the supply chain is localized, it is possible to lower the cost of offshore wind energy to the range of $0.07 /kWh by 2030, according to the DOE's National Offshore Wind Strategy. Less well understood, is that offshore wind - even at a higher cost initially - can lower energy prices. It is counterintuitive, but here's how: Electricity is sold in an auction market. Each energy resource is bid into that auction, at the cost of producing an extra unit of that energy ($/MWhr). That cost is primarily determined by fuel costs. Nuclear power, for example, has very low fuel costs and as a result it bids into the auction at a low price. On the other hand, coal has a comparatively high fuel cost and thus bids in higher than nuclear, or increasingly higher than even natural gas today. Once offshore wind farms are built and operating, their offshore wind energy will bid into the market at zero cost. This is because (again, once in operation) there will be no cost associated with producing an extra megawatt of offshore wind electricity because the fuel – the wind – is free. Let's use New Jersey as an example. While southern New Jersey has abundant nuclear resources and a lower overall energy demand, northern New Jersey is densely populated with the highest energy prices in the state. That's because of what's happening behind the scenes in the energy markets. Market price is set by the units that are needed to meet load. Today, without offshore wind, old, polluting, inefficient peaking units in the north are used to meet peak load demand and are setting the market price. When the New Jersey Energy Link is able to bring in offshore wind, and to move surplus lower cost clean nuclear and natural gas energy from southern New Jersey to northern New Jersey, those expensive peaking units will be displaced, and so the overall market-clearing price will settle at a much lower level. This is a benefit that will be enjoyed by all ratepayers in that market. Reducing Congestion and Improving Reliability In addition to impacting market-clearing prices, offshore wind carried by the Atlantic Wind Connection will also relieve costly grid congestion. Like heavy road traffic that slows the progress of people and goods, congestion on the electricity grid prevents lower cost and cleaner generating plants from serving customers. That is, when there is congestion on our grid, we cannot utilize the most efficient sources because they cannot get through. Think of the Atlantic Wind Connection as a north-south highway that allows the least-cost energy to flow freely, lowering prices and eliminating congestion costs. Improving the north-south transmission pathways in the Mid-Atlantic region with an offshore backbone also supports grid reliability and security. This region includes our nation's financial hub, major east coast transportation and chemical infrastructure, our largest naval base and other critical military and national security facilities, and the nation's capital. Energy flows into this region largely from west to east along major transmission trunk lines and from south to north. During times of grid stress, due to severe storms, cyber-attack, physical attack, geomagnetic storm, or other significant event, the AWC north-south backbone can provide that extra margin of controllable transmission capacity that can keep the lights on. It does this by providing an alternate north-south path for moving power away from damaged or overloaded west-to-east or north-south terrestrial transmission lines. about us TeamInvestorsPartnersOpportunityCareers NewsPress Release 14 Aug, 2013 Ongoing negotiations have been taking place between NJBPU and Fishermen's Energy pl... 25 Jun, 2013 (This is an Op-Ed submission from a group of wind developers, supply chain manufact... 10 Jun, 2013 People sometimes ask why an Internet company like Google has chosen to invest in th... 17 Jan, 2013 Background. The Chertoff Group (TCG) was retained by Atlantic Grid Operations to st... 21 Oct, 2013 Trenton, NJ – Atlantic Wind Connection said today it is unveiling a new contracting... 13 Jun, 2013 The New Jersey Energy Link (NJEL), the planned high-voltage backbone offshore trans... 05 Jun, 2013 The New Jersey Energy Link (NJEL) , the proposed offshore transmission backbone ... 05 Jun, 2013 Markian Melynk, President of the Atlantic Wind Connection, which plans to construct... {1} ##LOC[OK]## {1} ##LOC[OK]## ##LOC[Cancel]## {1} ##LOC[OK]## ##LOC[Cancel]##


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Using a combination of postures (asanas), breathing exercises, relaxation, and meditative techniques, yoga promotes overall health and well-being in a number of ways:
People of all ages and physical abilities can practice yoga. If you have any questions or physical conditions that you believe might prevent you from doing yoga, check with your physician or the yoga instructor at the center before taking your first class.
Kripalu Yoga: 5:30-6:45pm
Postures taught:
Postures are taught with emphasis on alignment and usage of yoga props (blocks, straps, bolsters, the wall) to facilitate a safe, thorough experience of the postures. Instruction follows the Kripalu system of "Breathe, Feel, Observe, and Allow." Posture modifications are gladly offered.
Emphasis on mindful awareness is maintained throughout the class and instruction begins and ends with brief meditation practice.
Teacher: Deanna Burkett, MA, MS, RYT, firstname.lastname@example.com
Cost: $12 per class; class size is small. Please email Deanna before attending.
Alicja W. Walczak, MS, CRS offers private, individual instruction by appointment only.
Call the Center for Integrative Medicine at 412-623-3023 with your name, e-mail address, and telephone number if you are interested in attending a YOGA class.
UPMC Center for Integrative MedicineShadyside PlaceSuite 310580 S. Aiken Ave.Pittsburgh, PA 15232
For general information or to schedule an appointment, call 412-623-3023.
Affiliated with the University of Pittsburgh Schools of the Health Sciences
| Supplemental content provided by Healthwise, Incorporated. To learn more, visit www.healthwise.org
For help in finding a doctor or health service that suits your needs, call the UPMC Referral Service at 412-647-UPMC (8762) or 1-800-533-UPMC (8762). Select option 1.
UPMC is an equal opportunity employer. UPMC policy prohibits discrimination or harassment on the basis of race, color, religion, ancestry, national origin, age, sex, genetics, sexual orientation, gender identity, marital status, familial status, disability, veteran status, or any other legally protected group status. Further, UPMC will continue to support and promote equal employment opportunity, human dignity, and racial, ethnic, and cultural diversity. This policy applies to admissions, employment, and access to and treatment in UPMC programs and activities. This commitment is made by UPMC in accordance with federal, state, and/or local laws and regulations.
Medical information made available on UPMC.com is not intended to be used as a substitute for professional medical advice, diagnosis, or treatment. You should not rely entirely on this information for your health care needs. Ask your own doctor or health care provider any specific medical questions that you have. Further, UPMC.com is not a tool to be used in the case of an emergency. If an emergency arises, you should seek appropriate emergency medical services.
Pittsburgh, PA, USA | UPMC.com


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Whether you're making the daily commute to work, nipping out for a spot of retail therapy or meeting up with friends, our small cars make getting round urban environments effortlessly enjoyable.
All our small car / hatchback models have been designed with modern city life in mind. In each of these small cars PEUGEOT's usual personality and style is clear to see. And naturally, they're remarkably fuel efficient – our economical small car models boast ultra-low CO2 emissions, while more than meeting the mileage demands of the busy modern motorist.
Stylish without compromising practicality, PEUGEOT's SUV range delivers the best of both worlds. They're compact, yet spacious. Rugged, but luxurious. Enjoyable and efficient. Whether you're zipping round the modern cities or challenging the great outdoors, there's a Peugeot SUV for you and your family.
Our SUV cars are robust, but feature all the elegance PEUGEOT is renowned for. Through spacious boot and cabin spaces, flexible interiors, and innovative storage compartments, these SUVs provide space for the kids, the suitcases and the deck chairs when the holiday season comes around.
Combining sporty style with mighty performance, PEUGEOT's range of hot hatchbacks deliver high thrills every time you take to the road. These hot hatches turn heads with their sleek lines, glistening chrome and distinctive alloy wheels. All of PEUGEOT's usual style is backed up with plenty of substance too. Our performance arm, PEUGEOT Sport, with decades of race car and rally motorsport experience, bring their expertise by aiding in the development in our performance car range.DISCOVER OUR HOT HATCH RANGE
Stylish in appearance, efficient in performance and great to drive, PEUGEOT's 508 sedan is designed with the driver in mind.
Through its elegant exteriors and classy cabins, the 508 sedan makes a lasting impact in a world where first impressions are everything. The luxurious cabin upholstery in our sedan car is complemented by innovations that ensure you and your passengers travel in supreme comfort.
PEUGEOT's range of wagons strikes the perfect balance between luxury and flexibility. They're versatile too, meeting the demands of everyday life – whether it's driving the kids to the park at the weekend, or travelling for business during the week. Plus each wagon model features elegant seating, sleek dashes, innovative technology and practical spaces.
With light and spacious cabins, our luxury wagon models provide comfort for both drivers and passengers. The panoramic glass roof (depending on the variant) allows lots of natural light to flow in. And if you need more room for storage, it's there. With the flick of a switch, the back seats on our 308 Touring and 508 Touring fold down to increase boot space.
Here at PEUGEOT, we believe that practicality doesn't mean the end of great driving experiences. And with SUVs and station wagons in our family cars range, there's a vehicle for every family – and every driver.DISCOVER OUR FAMILY CAR RANGE


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AJPW 1st Champion Carnival (Night 20) took place in Nagaoka, Niigata. The event took place on April 19, 1973. It was an event put on by All Japan Pro Wrestling.
- Numbers in parentheses indicate the length of the match.
- (c) refers to the champion(s) heading into the match.
- Singles Match: Mitsuo Momota defeated Munenori Higo (11:17)
- Singles Match: Samson Kutsuwada defeated Akio Sato (12:37)
- Singles Match: Moose Morowski defeated Motoshi Okuma (12:56)
- Singles Match: Masio Koma defeated Antonio Pugliese (15:06)
- Singles Match: Caripus Hurricane vs. Matty Suzuki - Double Count Out (13:08)
- Singles Match: Thunder Sugiyama defeated Baron Scicluna (13:02)
- Tag Team Best Two Out Of Three Falls Match: Hiro Matsuda & The Destroyer defeated Mad Russian & Mark Lewin [2:1] (25:02)
- The Destroyer defeated lewin (18:30)
- Lewin defeated The Destroyer (20:33)
- Matsuda defeated Mad Russian (25:02)
- Champion Carnival 1973 Semi Final Match: Giant Baba defeated Curtis Iaukea (11:49)
External links
|1973 All Japan Pro Wrestling events


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Status: Open
Know more about this business than we do? Cool! Please submit any corrections or missing details you may have.Help us make it right
Real Estate Cafe is a warm and inviting boutique-style real estate office where agents and clients love to gather and view properties by the fireplace with a fresh brewed cappuccino, much like the living room in their own home. Our goal is to put a personal touch back on the menu of home buying services.
In order to achieve these goals, the office had to have a few prerequisites: a red front...
Be the first OregonLive.com user to add photos or videos of Real Estate Cafe
I have had the great pleasure of working with Melinda Peterson for several years now. She helped me find my home in Grants Pass while I was still living in California. Our family had what seemed to be…
Since 2009, Real Estate Cafe has been providing Real Estate Agents And Managers from Grants Pass.


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Freehand Profit Releases 3 New Sneaker Masks!
This week Freehand Profit released photos of 3 new sneakers masks, all made from Way of Wade 4s yet each mask is completely unique. These aren't the first Way of Wademasks by Freehand Profit, last December for Art Basel:Miami he created 5 WoW masks for the Chinese athletics company Li-Ning, the maker of Dwyane Wade's signature basketball shoe.
"There's levels to the sneaker masks. The body of work speaks as a whole and each mask or group of masks also have their own voices. For masks 119, 120 & 121 they are a testament to the endless possibilities that come within even the same style sneaker. Like No. 108, the "Veteran's Day" WoW4 Mask, these masks pull their character from the way colors and materials are applied to the shoe as well as the various base masks that I build my sculptures onto. Leading to a unique and one-of-a-kind mask each and every time.
The masks are a reflection of our modern culture through an ageless tradition, from my vantage point as a supporter, participant and believer in Hip-Hop culture. Masks create and conceal identities, they can possess you or chase the demons away, throughout history they have been used in rituals & rites of passage, others are status symbols and objects of desire. Ritual is a ghost our modern eyes look for but don't recognize, we are unaware of our daily practice. It is said "We are what we worship", who are you deities?" - Freehand Profit
Check out FreehandProfit.com for more photos and info on this unique art form.


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- "Your current presence on Earth is unauthorized."
- ―TOY (from Aliens vs. Predator: Deadliest of the Species)
"TOY" was Montcalm-Delacroix's personal artificial intelligence computer mainframe that operated and maintained the Liberté. It created the White Hybrids after its systems became corrupted.
TOY was a revolutionary interactive computer system — a self-aware gaming and entertainment nexus. His purpose is to transform dreams into reality. It's computer system able to keep references on certain people. TOY first meets Major Shirow and Colonel DeMedici when they board the Liberté in search of a predator. Later, when Caryn Delacroix begins have recurring nightmares of being killed by a predator, he assures her that she is only troubled, not insane, as she does not fulfill any parameters indicating that she is. He is responsible for the virtual realities she finds herself in, and while she angrily states that their terrifying nature have caused her harm (which he cannot cause, as per the laws of robotics). However, TOY reveals those realities were 100% real and that the corporation in charge of her simply went to great lengths to make it seem false. Caryn questions why they bothered, but TOY does not answer, saying the knowledge would put her at risk, therefore break one of the laws.


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2015 Performances
Fri Jan 2
Visionaries with Hawkeye Slow To Speak The Spectators and A Work of Fiction
House of Blues - Cleveland
A Visionaries setlist is a compilation of all the songs Visionaries has played live in concert. Many Visionaries concerts have the same setlist, and sometimes Visionaries setlists will vary from night to night. We've gathered together 2017 Visionaries tour setlists as well as past Visionaries setlists to give you a better idea of what you can expect at your local Visionaries show. If you have a Visionaries song list you would like to upload, please check back as that functionality will be added soon, as well as setlists for Visionaries.


text: Infant Crisis Services volunteer, Laura Bruegen, has made several quilts for us lately. Today, a 3-year-old Natalie specifically told us her favorite color was purple so Ana wanted me grab her a purple blanket. Moments later Laura showed up with this quilt so we let her present it to little Natalie. This is a shot I got of the both of them.


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(see above)— weavings that may explain how the Incas ruled without a written language — still in ritual use.
Image:A khipu from the Nazca River valley
Quipus or khipus (sometimes called talking knots) were recording devices used in the Inca Empire and its predecessor societies in the Andean region. A quipu usually consisted of colored spun and plied thread or strings from llama or alpaca hair. It could also be made of cotton cords. The cords contained numeric and other values encoded by knots in a base ten positional system. Quipus might have just a few or up to 2,000 cords." (source:http://en.wikipedia.org/wiki/Quipu )


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Inspire confidence in your game with the sleek and technology-driven Ping G25 Irons. The incredible game improvement techology in this iron set will give you a higher ball trajectory, more distance and extreme distance, all in one sleek, stylish iron. The custom-engineered face structure ensures a solid feel and distance with control. Progressive sole widths help optimize CG placement for accurate distance gapping. In appearance and performance, these 17-4 stainless steel designs will appeal to golfers of all abilities.
The custom tuning port (CTP) is integrated into the sole to lower the mass and position the CG for long, high-launching, forgiving results. The CTP aligns directly with the impact area, allowing for a lower CG and a high MOI. Face support bars and low-toe weighting stabilize the face to ensure a solid feel and exceptional distance control throughout the set.
A multi-material cavity badge made of aluminum and a soft elastomer ensures a solid sound and feel. The progressive sole widths provide higher-launching, more forgiving long irons, and short irons with added playability and control. Thinner top lines and moderate offset offer a look that will appeal to a wide variety of golfers looking for a high-launching, extremely forgiving game-improvement model.
Ping G25 Left-Hand Steel Irons Feature:
- Set includes: 4-PW, UW
- Black Dot
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Shipping Info
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Austads.com offers simple, flat-rate shipping to destinations in the continguous U.S. via UPS.
- Ground (3-5 business days) - $7.99
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Austad's Golf is centrally located in Sioux Falls, South Dakota. Most items ship directly from our warehouse there and average 3-5 business days for ground delivery. See the map below for estimated ground shipping delivery times for your area.
"Overnight" shipments will arrive the next business day (excluding weekends and holidays) after departing Austad's Golf. "2-Day Air" shipments arrive in two business days after departing Austad's Golf. On-time delivery for both methods is guaranteed by our preferred carriers.Shipping delays may occur during busy Holidays or in the spring -- we will do our best to accommodate last minute and expedited orders placed during these times.
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Due to manufacturer restrictions, we cannot offer free shipping on any order with PING products. Some oversize items such as cart bags, package sets and travel covers are not eligible for free shipping.
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Austad's Golf has physical locations and charges sales tax on orders shipping to the following states: Iowa, Minnesota, Nebraska, North Dakota and South Dakota. Orders shipping to states other than the five listed will not be charged sales tax.


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Hometown: Brooklyn, New York City.
The lineup: Lorely Rodriguez (vocals, music).
The background: Meet the new Grimes, the female electronic pop artist who is going to make the biggest splash this year. Rodriguez is like a Lana Del Rey raised on Liz Fraser rather than Julie London. Hers are torch songs from another dimension, with an acrobatic voice to match. There are three tracks out there – Champagne, Don't Tell Me and Hat Trick – and they are all sensational: you imagine you can touch them, taste them, see them. This synaesthetic quality obviously occurred to Rodriguez, because she originally made her music available via a series of colour-coded soundbites called Colourminutes, some of which she has subsequently developed into full-length pieces, such as Don't Tell Me and Champagne.
The colour thing is all part of her plan, she explains, to "reveal information about me or the project but in a super non-literal way". But don't worry: for all her arty pretensions – and we love pretentious artists, we really do – there is no sacrifice of pop accessibility in the pursuit of the high-flown idea. Or rather, they dovetail beautifully. Like Grimes – and Björk and Kate Bush, for that matter – Rodriguez is fully involved in the writing and recording of her music. She is part of a new wave of female electronic auteurs that also includes Laurel Halo, Maria Minerva and Nite Jewel, whose music wanders freely between genres, alighting on synthpop and dreampop, with a sort of shoegazey haziness, plus a tacit acknowledgement in the production of more recent developments in electronica.
The first single to be released in Britain, in April, will be the Systems EP, with two songs in English – Hat Trick and No Means No – and two in Rodriguez's native Spanish; Tristeza and Camisa Favorita. The first means "sadness", the second "favourite shirt", although it is unlikely to be a cover of the similarly titled Haircut 100 hit, but you never know. We've only heard one of the EP tracks: Hat Trick, a seriously lush and melodic indie-pop song. Elsewhere on her SoundCloud there is Don't Tell Me, a slow-moving glacial affair that leaves one in awe. Older track Champagne finds Rodriguez tentatively mapping out places for her voice to go and comes accompanied by a video that sees her gorging on a watermelon.
Reading this on a mobile? View here
The buzz: "A delightful mix of abstract lo-fi retro sounds and glistening melodies with a nostalgic feel." (Dazed Digital).
The truth: It's all Systems go for this Empress.
Most likely to: Get out the bubbly.
Least likely to: Do a somersault on her head.
What to buy: The Systems EP is released by Double Denim in April.
File next to: Grimes, SZA, Liz Fraser, Björk.
Links: soundcloud.com/empressof/systems-hat-trick/s-Kwqcd


text: To get from Grottaglie to Venice by train you can catch one of the 1 trains that everyday travel between these two cities. The first train to Venice leaves from Grottaglie at 05:30 and the last train departs at 05:30. If you choose a local train the trip lasts on average 10:39 hours. For your trip from Grottaglie to Venice by train you can choose to leave from one of Grottaglie main stations: Grottaglie On Wanderio you can compare all schedules, fares and railway companies to Venice and book the best itinerary starting from Grottaglie.


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How to Get Rid of Stretch Marks
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Being pregnant and working at the same time is good, but it is not recommended at all times.
When it comes to hairstyles, there is no limit but for office you need something clean and sophisticated with a little extra "oomph".


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We can give you advice on a wide range of commercial short-term insurance products to cover every aspect of your business, including:
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7291 Oakridge Drive, Ypsilanti 48197
See more homes for sale in Ypsilanti, MI
This property has been Sold!
08/15/2016 at $197,500
Spacious 4 bedroom, 2 1/2 bath home with over 2200 Total Square Feet in the sought after Parkside Preserve Subdivision. Very large fenced back yard and large deck, great for entertaining and surrounded by a privacy fence, offers great space for your children's playground. This home offers great space both inside and out with updates, tile and hardwood floors, fireplace and comfortable finished basement giving this home everything you would need to make it your own.
Property Information
- Total Finished SqFt
- 2,226
- Lower Finished SqFt
- 480
- Above Grade SqFt
- 1,746
- Garage Desc.
- Attached, Door Opener, Electric, Heated
- Water
- Public
- Sewer
- Public
- Year Built
- 1999
- Home Style
- 2 Story, Colonial
- Summer Taxes
- $2,166
- Winter Taxes
- $1,460
- Association Fee
- $115
Rooms and Land
- MasterBedroom
- 16 x 17 2nd Floor
- Bedroom2
- 11 x 12 2nd Floor
- Bedroom3
- 10 x 14 2nd Floor
- Bedroom4
- 13 x 14 2nd Floor
- Breakfast
- 9 x 12 1st Floor
- Dining
- 9 x 12 1st Floor
- Kitchen
- 9 x 12 1st Floor
- Living
- 17 x 17 1st Floor
- Basement
- Partially Finished
- Cooling
- Central
- Heating
- Forced Air, Gas
- Acreage
- 0.24
- Lot Dimensions
- 85 x 132 x 72 x 137
- Fireplace Desc.
- Gas, One
- Interior Features
- Ceiling Fan(s), Master Bath, Security System, Sump Pump
- Exterior Materials
- Vinyl
- Exterior Features
- Cable Available, Deck, Fenced, Porch
Listing Video for 7291 Oakridge Drive, Ypsilanti MI 48197
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Listing Broker
Listing Courtesy of Re/Max Platinum
Office Address 325 W. Eisenhower, Suite 200
Listings last updated: . Some properties that appear for sale on this web site may subsequently have been sold and may no longer be available.
Our Michigan real estate agents can answer all of your questions about 7291 Oakridge Drive, Ypsilanti MI 48197. Real Estate One, Max Broock Realtors, and J&J Realtors are part of the Real Estate One Family of Companies and dominate the Ypsilanti, Michigan real estate market. To sell or buy a home in Ypsilanti, Michigan, contact our real estate agents as we know the Ypsilanti, Michigan real estate market better than anyone with over 100 years of experience in Ypsilanti, Michigan real estate for sale.
The data relating to real estate for sale on this web site appears in part from the IDX programs of our Multiple Listing Services. Real Estate listings held by brokerage firms other than Real Estate One includes the name and address of the listing broker where available.
IDX information is provided exclusively for consumers personal, non-commercial use and may not be used for any purpose other than to identify prospective properties consumers may be interested in purchasing.
Provided through Ann Arbor Association Board of Realtors. © 2017 Ann Arbor Associate Board of Realtors Ltd. shareholders.


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Grealish Wembley wonder show may hit Irish hopes
Jack Grealish was the star of the show as Aston Villa stormed into the FA Cup final with a victory against Liverpool at Wembley on Sunday - and that may be bad news for Republic of Ireland boss Martin O'Neill.
Grealish has kept the Irish soccer chiefs waiting over whether he will commit his international future to the green shirt, even though he has represented Ireland at junior levels and was recently named as the FAI's Young Player of the Year.
His apparent eagerness to wait and see whether England - the country of his birth - would show an interest in calling him up may have moved a giant step closer as he turned on a cultured display in Villa's famous cup victory.
It came as little surprise that his extravagantly spoken manager Tim Sherwood was full of praise for the 19-year-old after his side's 2-1 Wembley win, as he offered this glowing tribute.
"He could be right up there amongst the best of them," declared Sherwood. "The ball is his friend.
"He likes to receive it he doesn't look at it, he knows where it is, he shifts it, he's got a turn of foot, takes a lot of knocks, but he can take it. He's a big lad.
"He's Aston Villa through and through. He lives a couple of miles from the ground, he just wants to play for the club and I want to give him the platform to do that because he's earned the right."
A delighted Grealish spoke to the BBC after the game, as he revelled in the best moment of his career so far.
"It was brilliant for me to play at Wembley at my age and go one to win," said Grealish. "Now we want to go on and win it.
"I thank the gaffer for giving me a load of belief and hopefully that will continue for the rest of this season."
The English media are already speculating that Grealish could be approached by the FA in London after his Wembley heroics, with Ireland boss O'Neill and the FAI needing to try and hasten the decision that has yet to be made and try to swing it in their favour.


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G.I. Joe: Retaliation Blu-ray
Starring Channing Tatum, Dwayne Johnson, Bruce Willis, Adrianne Palicki, Ray Stevenson, Ray Park, Elodie Yung, Walton Goggins, Byung-hun Lee, Joseph Mazzello, Arnold Vosloo, RZA
Directed by Jon M. Chu
Bruce Willis and Dwayne Johnson star in this action thriller sequel based on the range of Hasbro action figures.
This time around, the G.I. Joe Team must fight to wrestle back control of the world from the Commander (Faran Tahir) and Cobra spy Zartan (Arnold Vosloo), last seen disguised as the President of the United States.
Outnumbered and outgunned, the Joes must pull together a plan to expose the truth and stop Cobra from taking over the world before it is too late.
- Format: Blu-ray
- Region: ABC
- Certification: (12)
- Catalogue number: BSP2478
- Studio: Paramount Home Entertainment
- Release date: 22/07/2013
- Genre: Action/Adventure
- Colour: Colour
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Also directed by Jon M. Chu | View all


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found a new home!
Plenty of my friends are looking
for one too. Find a pet to adopt.
I am already neutered, housetrained, up to date with shots, and good with dogs.
Bugzy, a Somerset Beagle/Pug dog was adopted! Here's how you can benefit by looking at adoption as an option to buying a Beagle/Pug for sale in Somerset, or seeking a Beagle/Pug dog from a breeder in Somerset.


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King George III After the Revolutionary War... Interesting Facts... Influential in the formation of our country? Known as Farmer George King George III's proper name... Defeat Sanity was questioned Son took over power Death Very influential Known as "Farmer George"
Went mad--Porphyria?
Real Name
Death Defeat Sanity was questionable Very Influential.
Laws are based on his mistakes. Defeat Sanity questionable Power control Death Jobs he had? How'd he become king? Because of his father's (Frederick Prince of Wales) death while his father (King George II) was still alive.
His son was next in line for the throne. Making him King George III :D none! Was he Part of the revolutionary War? King George III created many acts to tax the colonists during The Revolutionary War. The Stamp Act -taxed on all paper items The Sugar Act -taxed on all tea materials -made colonists angry The Quartering Act -soldiers could enter home What was his childhood like? --Because the U.S. won, people thought that it would have hurt King George III But instead, it actually made King George III more popular Born June 4, 1738
in London, England Was he part of our Constitution?? Pretty smart kid At 12 years old, his father passed away nope not really George's Love Life (; King George III married the day he met her! The couple had 15 children 3 kids succeeded to the throne In Conclusion...
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King George III
By Kyndra, Mikayla, and Sam Using this for our presentation in History class..
Samantha Fogalon 28 March 2011
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THE federal government has said it will spend billions of dollars to combat bioterrorism in our midst. But how much money will Americans waste first?
There is no question that news reports of a baby and others being exposed to anthrax in the middle of Manhattan are terrifying. In some cases, the Centers for Disease Control and Prevention is recommending that people who have no symptoms and have not tested positive for anthrax exposure take antibiotics as a precaution.
But according to health care officials and doctors themselves, hundreds of prescriptions for ciprofloxican, or Cipro -- the drug that is believed to be most effective in treating anthrax -- are being doled out to people who have no reason to believe that they have ever been exposed to the deadly disease. And New Yorkers are running to the city's emergency rooms in droves -- in many cases bypassing their own private doctors -- to see if that cough, sniffle or blemish is actually evidence of anthrax exposure.
These hospital runs ''are overtaxing very valuable resources,'' Dr. Neal L. Cohen, the New York City health commissioner, said at a news conference at City Hall last week. ''It doesn't make sense economically,'' he added, ''and it doesn't make sense medically.''
That is especially true because the city's health and emergency management workers are already busy gearing up for other possible attacks, training workers and checking their own pharmaceutical supplies.Continue reading the main story
William Grice, vice president for operations at Saint Vincents Hospital and Medical Center in Manhattan, said its already busy emergency room has been filled with people anxious about anthrax. Doctors have had to be diverted from patient care to lead impromptu educational groups.
''People who really do not fit the protocol for needing treatment are demanding it,'' he said. And the hospital's costs are already mounting: about $250,000 to build up stockpiles of drugs, $50,000 for decontamination supplies and training for the emergency department and $30,000 to upgrade equipment on ambulances for paramedics.
''Those are the short-term things we have done,'' Mr. Grice said. ''We feel we have to do more long-term planning.''
Misuse of antibiotics is not new. The C.D.C. has even devoted a division to combat this problem, which can lead to resistant strains of illnesses and undesirable side effects. Cipro and similar drugs can cause nausea and diarrhea and, in rare cases, seizures and convulsions or worse. Mayor Rudolph W. Giuliani, who took it for urinary tract infections, said he found it to be unpleasant and would not take it now unless he had to.
Doctors are often pressured by nervous patients to prescribe antibiotics that they do not need. But that does not mean that doctors should do it. ''It is slightly irresponsible,'' said Dr. Kevin M. Cahill, a tropical-medicine specialist in Manhattan. ''We're drawing down a finite reserve for reasons that are not warranted. And there are real dangers in taking Cipro.''
As it stands, the federal government and the pharmaceutical industry have already taken steps to increase the production of Cipro and approve a broader range of drugs that might be used for anthrax illness. Tommy G. Thompson, the secretary of health and human services, said the government would approve two generic, broad-spectrum antibiotics, doxycycline and penicillin, for those who have inhaled anthrax.
All of this has caused Bayer, the German company that holds the patent for Cipro, to consider whether it should, in effect, abandon its patent by permitting generic drug makers to produce Cipro for sale in the United States, as some have said they are prepared to do. This also raises questions of whether the drug industry will again be pressed to rethink sticky patent and pricing issues.
There is no question that these are scary times. Anyone with a child cannot help but be gripped by at least momentary fear. Flu and cold symptoms, so common this time of year, can instill the same worry in any American these days.
But there are some cost-benefit decisions that have to be weighed. Do you really want to take up the time of an emergency room -- and in some cases, foot at least some of the bill for the visit -- when workers there may need to care for others who are critically ill, perhaps, someday, someone in your own family? Should the public health dollar be stretched away from education and prevention efforts to responding to questions that can be answered online at www.cdc.gov, the Web site of the disease control centers?
PERSONAL doctors, who are often too busy to come to the phone, might be better used as resources when true symptoms are present. ''It is amazing how much time it takes to answer calls from patients all day long wondering about anthrax,'' Dr. Cahill said. ''I tell them I will fax the C.D.C. Web site page to them.''
The government, of course, does not always tell the public everything it knows. In an age when we have come to expect instant answers, its method of distributing information can seem maddeningly incomplete and snail-like. But the facts about the anthrax threat and appropriate responses seem to evolve by the day. This illness, and this war, are new to the government. Public hysteria has its own health risks, including financial ones, and this may not be the best time to take them.Continue reading the main story


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Dierks Bentley Gets Ready to Rock at the 2014 CMT Awards
He's always up for some southern-fried fun and sex appeal, so it's not surprising that Dierks Bentley showed up at the 2014 CMT Awards earlier tonight (June 4).
The "I Hold On" star gave the ladies at Nashville's Bridgestone Arena a thrill as he moseyed past the paparazzi, stopping for a few photos along the way.
The CMT Music Awards is the only show of its kind where the winners are determined by fan voting and competition is always pretty fierce.
This time around, Kristen Bell is manning the hosting duties and performers include Miranda Lambert, Carrie Underwood, Eric Church, Little Big Town, Luke Bryan, Keith Urban and Lady Antebellum.


text: New FREE image coming SOON! We apologize ...We have not posted to this blog for a long time due to illness and the passing of a loved one. We also had no idea our beautiful background that complemented our banner was deleted somehow. Thank you kindly for your patience and kind understanding...Please check back SOON!


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some of the staffs are friendly , the hotel is very beautiful although my room has some roaches, but that happen with visitors in and out , the cleaning staff could have caught it. the pool is amazing my wife and kids enjoyed it, overall...More
Getting you more information on this room
Getting you more information on this room
"Building 10, 11, 12, 13, & 14 will be beachfront and quieter at night"
"Depends of your taste, if you like to be close to the beach then choose sea view ."
"Beach front is the way to go, birds start chirping at 5am so they are your natural alarm lol."


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President Barack Obama touches names of the 9/11 victims as he visits the North Memorial Pond at the National September 11 Memorial ceremony in New York. (Photo: AP Photo/Pablo Martinez Monsivais)
President Barack Obama and former President George W. Bush marked the 10th anniversary of the Sept. 11 attacks at the World Trade Center Sunday.
Bush and Obama, joined by their wives, ran their hands over bronze panels bearing victims' names at the Sept. 11 memorial, writes the Associated Press. The twin reflecting pools built over the towers' footprints will open to family members later Sunday for the first time.


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Wilted endive salad
Anjuli's grandmother, my mom, was born in 1910. She did not cook much until she married in 1940, as far as I know. She went through WWII as a wartime bride, exposed to rationing and culinary marvels like Scrapple and Spam. I was a baby boomer, born in '47, so for me her cooking style was a product of the 50s. She delighted in post-war conveniences: plastic bags, frozen vegetables, cold soda, Tastykakes and Entenmann's, en masse condiments like mayonnaise and ketchup, and keeping leftovers in the fridge (sometimes too long in my opinion). And she loved iceberg. Salads at home were invariably iceberg, tomatoes, carrots, onions and one of ten kinds of bottled dressing. The only exception to this rule was her wilted endive salad. She'd even make her own dressing. We always ate it as a main course because of the ample bacon and hard boiled eggs. I loved this salad for its heartiness, the texture of the curly, wilted endive, the sweet and sour tones of the dressing, and the lovely, crispy bacon. It satisfied all the tastes. It stood alone beautifully.8 Comments » Keep reading »


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Random Questions #12
>> Saturday, December 27, 2008
1. What payment do you hate paying the most? Utility bills.
2. Where was the last place you had a romantic dinner? I can't remember because we don't usually go out at night.
3. If you could go back and change one thing what would it be? Secret. Hehe. A mistake though it does not matter now.
4. Name of your first grade teacher? Mrs. N.
5. What do you really want to be doing right now? Go to the malls with Ted. I want to check-out the good deals while he is looking for a good Hansgrohe faucet for a client's kitchen.
6. What did you want to be when you grew up? A teacher.
7. Why did you choose the shirt that you have on right now? It is sleeveless and comfortable.
8. What are your thoughts on gas prices? It can be brought down naman pala eh! Some people are just way too greedy!
9. First thought when the alarm went off this morning? Twilight surely made me sleep so late. Good thing we're still on a vacay!
10. Do you miss being a child? Not really. I love where and what I am right now.
Thanks, Chikai! You are a lifesaver!


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Built in 1880 and renovated in 2004, this city hotel includes 24 rooms over 6 floors, including 6 singles and 10 doubles. The stylish foyer hall includes a reception, which is manned around the clock. The hotel also features lifts, safes, a TV room and an Internet terminal. Other facilities include a breakfast room and a laundry service.
This charming hotel is situated at the heart of the city's tourist centre. Many of Paris' sightseeing attractions are nearby, such as the Champs Elys�es and the Arc de Triomphe. Numerous shops, restaurant, bars, pubs and public transport links (George V metro station) are only a stones throw from the hotel. Gare Saint Lazare train station is roughly 15-minutes walking distance and Monceau Park is only around 10 minute away. The transfer time to Orly airport takes around 30 minutes and Charles de Gaulle airport is around 45 minutes away from the hotel.
The comfortable rooms feature en suite bathroom facilities with a hairdryer, a direct dial telephone, a safe, satellite TV as well as Internet access.
A breakfast buffet is available to guests each morning.
All credit cards, including American Express, Diners Club, MasterCard and VISA are accepted.
The room capacity for all rooms is of 2 persons maximum. It's not possible to be 3 or more person per room.
Room Facilities:
Direct dial telephone
Satellite cable TV
Internet access
Central heating


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As you can see, life is nowadays much easier thanks to the internet which provides us with many easy hacks, such as this one. After watching this video, you will never again find yourself in front of your car desperately trying to find your lost key. Instead of that you will use this simple trick to instantly unlock your beauty.
source : www.dirtywheel.com
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Call Today for Professional Representation of Your Interests
The team at Bassett Law understands the moments of legal uncertainty when life changes. Our collective experience and commitment to each client's well-being guides us in helping you fulfill your immediate and future legal needs, especially because throughout life those needs change.
Why opt for Bassett Law As life changes, our expert services, dedication to you, and compassionate approach to the law remain certain. We know what we're doing. You can count on us. Our clients' peace of mind is our highest priority.
Contact us today if you need legal assistance with any of the following:
- Elder Law
- Care Mangement
- Disability Law
- Medicaid Planning
- Estate Planning
- Disability Law
- Guardianship and Conservatorship
- Probate and Estate Administration
- Mediation
Call Attorney Jane Bassett today at 734-930-9200 to arrange your initial consultation.
Attorney Profile
Attorney Jane Bassett
- Michigan
- University of Detroit Mercy School of Law
Professional Memberships and Achievements:
- National Academy of Elder Law Attorneys (NAELA)
- Elder Law and Disability Rights Section of the State Bar of Michigan


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#ThisOppressesWomen Stickers Going Global
- Details
- Category: Actions
Over the past few days, the stickers created by National Women's Liberation and Redstockings have been covered by reporters in the U.K., India and the U.S.
We are sick of being bombarded with advertisements that depict women only as sexual objects.That use our bodies to sell products. That embolden men to disrespect us. That tell us we are not worthy unless we conform to unrealistic, sexist, racist and unhealthy beauty standards.
Help make this go viral. If you see a sexist ad photograph it and put it out with the hashtag #THISOPPRESSESWOMEN. Do the same if you spot the stickers on any ads.
Retweet some of our tweets @4womenslib
Join Us at the Feminist Video Booths
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- Category: Actions
We have been distributing #ThisOppressesWomen stickers for slapping on sexist ads, and we're taking the campaign further. Help us create a video that will showcase women's testimony.
We'll be asking: How are you oppressed as a woman? How does sexism affect you?
Sunday Sept 20th, 1pm-3pm
Meet outside the Atlantic Center, corner of Atlantic Avenue and Flatbush Avenue (near the Guitar Center).
Tuesday Sept 29th, 5pm-7pm
Meet at the Ghandi statue in the southwest corner of Union Square
10.5.15 - Women of Color Discuss Organizing in Mixed-Race Groups
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As women of color, we are involved in various struggles for freedom and social justice. As a result we often find ourselves working with or in solidarity with white allies. Join the Women of Color Caucus for a consciousness-raising meeting on Monday, October 5th at 7:00 p.m. EST to discuss our experiences organizing in mixed-race groups or coalitions (successes, challenges, etc.).
This meeting is open to women of color. You can join us for this meeting in person in:
Women's Liberation Meetings Brochure
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- Category: Actions
What Women Really Want for the Holidays flyer
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- Category: Actions
This flyer was written by the Gainesville Women's Liberation community education class, "Women's Liberation: Where Do I Fit In?" as part of a class action.


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Class Action Defense
Nelson Mullins lawyers are experienced in class action and litigation in the Southeast and beyond. In the fields of consumer financial services, insurance, environmental law, healthcare, labor and employment, product liability, unfair and deceptive trade practices, utilities and securities, Nelson Mullins lawyers have defended class actions in state courts, federal district courts, bankruptcy courts, and circuit courts of the United States Court of Appeals locally, regionally, and nationwide. In addition to traditional class actions, we are experienced in defending claims raised in "opt-out" litigation.
We are able to team experienced class action litigators with practitioners from various fields to meet the needs of the client and the case. From the beginning of the case, where proper understandings of jurisdictional issues and the viability of plaintiffs' claims are critical, through the class certification stage, where appropriately framing the issues may affect the outcome, to the end of the case, where good counsel about the risks of litigation and effective advocacy on the merits establish the basis for success, Nelson Mullins attorneys bring to bear our knowledge and experience, our work ethic, and our dedication to excellent client service.
Having served as national, regional, and local counsel to defendants in multi-district litigation (MDL), we offer experience of not only the procedures but also the various strategies employed by our clients' adversaries in industry-wide litigation. We have appeared before the Judicial Panel on Multi-District Litigation and have served as lead counsel for our clients in MDL proceedings. Nelson Mullins attorneys are currently serving as national coordinating counsel in industry-wide litigation in the fields of pharmaceutical and electrical products.
We also offer the latest in technology and case-management solutions in MDL and class action litigation. We regularly assist clients faced with the challenges of discovery management and "e-discovery" in litigation and class actions. Our class action defense practice includes working with clients to create solutions to difficult issues related to databases containing information about putative class members.
A sampling of our cases:
- As national counsel for a manufacturer of pharmaceutical products in MDL proceedings, we were part of the defense team that defeated nationwide and regional class certification of "economic damages" claims arising under warranty and consumer laws.
- In another "economic damages" putative class action consolidated in MDL proceedings, we are defending one of three manufacturers in litigation that challenges a product widely used by consumers across the country.
- We are serving as liaison counsel in MDL litigation, representing an insurer charged with racial discrimination in the setting of life insurance premiums.
- In a "bilateral" class action, certified by the trial court as to plaintiff and defendant classes, we represented a group of defendants in what turned out to be the leading case on class certification from the South Carolina Supreme Court, as we argued for reversal of the trial court's rulings on class certification.
- Representing a mobile home manufacturer in putative class actions based on allegations of defective soil anchor tie-down systems, we argued for summary judgment before the courts reached the issue of class certification.
- In another case for the same manufacturer in Maryland Circuit Court, we argued for precertification summary judgment on plaintiffs' claims based on an allegedly improper method for installing footers for manufactured housing above the frost line.
- In the seminal case in South Carolina on the application of the state's "door closing" statute to class actions, we argued, and the state supreme court held, that the statute precludes certification of a nationwide class in state court.
- We represented the prevailing party in a leading case from the Fourth Circuit Court of Appeals on the "cutting edge" jurisdictional issue of whether the "supplemental jurisdiction" statute, 28 U.S.C § 1367, overruled the U.S. Supreme Court's decision in Zahn v. International Paper.
- In federal district courts, we represented mortgage lenders who were charged with violating the Real Estate Settlement Procedures Action and prevailed in arguments against class certification.
- Representing mortgage lenders in a number of cases arising under the South Carolina Consumer Protection Code, we argued against class certification in a number of cases, prevailed on precertification summary judgment motions in others, and negotiated favorable class settlements in others.
- In a number of cases in federal district courts, we have argued against class certification in cases arising under RICO.
- We are currently defending several cases in which plaintiffs assert wrongdoing related to credit insurance sold in consumer loan transactions.
- We represent a manufactured housing company in this litigation. Originally filed as a class action, after discovery and briefing, the Court denied class certification, and the case continues as a multi-district litigation involving tens of thousands of claimants. Nelson Mullins is actively defending this action for its client.


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The Tedeschi Trucks Band — featuring Derek Trucks' slide-guitar virtuosity, Susan Tedeschi's soulful singing and blues guitar, two drummers and three-piece horn section punch — is a roots-music powerhouse ripe for the New Orleans Jazz and Heritage Festival.
Trucks, who shares the band's name with his wife, Susan Tedeschi, said the group performs a collision of the many styles of music heard at Jazz Fest.
"It's a roots-music band at its core," Trucks said from the home he shares with Tedeschi and their two children in Jacksonville, Florida.
"But this band can do a lot of different things," he added. "The guys on stage, when the gig's over, they can hit any jazz stage in the world and hold their own. And Susan with an acoustic guitar in front of a microphone, she can command any stage."
Trucks met Tedeschi, his future wife and bandmate, at the Saenger Theatre in New Orleans in 1999. He was then in his first year as guitarist with the Allman Brothers Band, half of the band's signature double-guitar attack with Warren Haynes.
Tedeschi, leading her own band at the time, had just joined the Allman Brothers Band tour as opening act. At the Saenger that day, Trucks and Allman Brothers Band bassist Oteil Burbridge stepped into the theater during Tedeschi's soundcheck. As usual, they were checking out their opening act.
Trucks, the nephew of drummer Butch Trucks, a charter member of the Allman Brothers Band, had seen many up-and-coming blues artists. He'd always come away disenchanted, but Tedeschi knocked him out.
"I remember being taken aback at how powerful her sound was, her guitar playing and her singing," he said. "I remember thinking, 'There's legit stuff going on here. She could be on stage with Magic Sam in Chicago and he wouldn't bat an eye.' "
Tedeschi and Trucks spent time together during the tour, hanging out and listening to music. They married in 2001. In 2010, they formed the Tedeschi Trucks Band, which returns Friday to the New Orleans Jazz and Heritage Festival.
It took some years for Trucks to leave the Allman Brothers Band, but he and Tedeschi have both left their respective earlier groups to devote their full musical attention to the Tedeschi Trucks Band.
"There's something about making music the way that we're making it," he said. "The honesty of it really wipes away a lot of the cloudiness."
The band is an unusually large group. Eleven musicians plus the crew equals an entourage of 20.
"When we first put this thing together, the management and people who were looking out for our best interests wanted to make sure we weren't losing our minds," Trucks said. "We didn't put this band together to squeeze dollars, that's for sure. But the venues and the promoters appreciate that it's a labor of love. They know what it takes to bring a band like this on the road."
Trucks learned lessons about being in a band through his 15 years with the Allman Brothers.
"Half of their story is problems that weren't dealt with for 10 or 15 years that came raging back," he said. "When we put the Tedeschi Trucks Band together, Susan and I were like, 'It's not going to be that way. If something ain't working, we're going to deal with it.'
"It really is a great group of people. Everybody cares about making it work. As we make more records, as we tour more, everybody becomes a little more selfless. Whether it's soloing or whatever, it's about the band more and the individuals less. Everybody wants it to be as good as it can be."
Both Trucks and Haynes left the Allman Brothers Band at the end of 2014. In that 45th anniversary year of the group, Trucks said, "everybody was back on track. There were a few bumpy years there between the 42nd and 44th anniversaries, when things weren't quite correct. People were dealing with health things, all kinds of stuff going on. It wasn't up to the level it needed to be. I didn't want to see it go out like that. Maybe I hung on a little longer for it to get back up to speed. It ended right."


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Ever so often a wedding anniversary gives you something to celebrate. Now Golden and Diamond anniversaries are not really uncommon, but do you know the names of the other anniversaries ?
The names that were given to wedding anniversaries came from ancient folk customs, of which the origin can not even be traced anymore. They usually referred to materials, of which the value increased, along with the number of anniversary years. Some other lists are even named after flowers !
Different materials were chosen, according to the region where they were found. Some were valued more or less, according to the local market. For example, in the Netherlands some anniversaries have other names than in Belgium, even though the two countries are neighbors...
The earliest references to wedding anniversaries date from the 1800's. They seem to have originated in the Germanic region, where the custom was for the spouse to give his wife a silver garland when they had been married for twenty-five years. Gold became the second traditional wedding anniversary, after fifty years.
Note however that the average life expectancy was not as long as it is today ! In several European countries, therefore twelve and a half years of marriage were celebrated using Copper as the anniversary symbol. Around 1875, another newcomer was the fifth anniversary, with wood.
There are two Diamond anniversaries, one at 60, and one at 65 years. The 60-year mark was added in 1897, when Queen Victoria celebrated the sixtieth anniversary of her accession to the throne in 1837. The difference between the two materials is the crude and the cut diamond. In some lists, the latter is replaced with a blue sapphire.
Before 1937, not all wedding anniversaries were represented by a material. Only the first anniversary and important ones such as 10th, 20th, 25th, 50th and 70th year were named. Later, more materials were added, and the list was continuously updated by commercial companies, to increase the sales of presents.
In 1937, the American National Retail Jeweler's Association issued a more comprehensive list. It associated a material for each anniversary year up to the 15th anniversary, and then each fifth year after that up to the sixtieth Anniversary. The next anniversaries were added later, as the average life expectancy increased !
There are many slightly different lists of wedding anniversary names, and so a search can become somewhat confusing.
The first anniversary is rather humorous, and perfectly fits newlyweds. It takes place after only 14 days and carries the symbol of Paper...
1 to 9 years 10 tot 19 years 20 tot 49 years 50 tot 80 years 1 : Cotton 10 : Tin 20 : Porcelain 50 : Gold 2 : Cardboard 11 : Steel 25 : Silver 55 : Emerald 3 : Leatherr 12 : Linen 30 : Pearl 60 : Diamond 4 : Wax 12½ : Copper 35 : Coral 65 : Diamond (cut) 5 : Wood 13 : Lace 40 : Ruby 70 : Platinum 6 : Iron 14 : Ivory 45 : Sapphire 75 : Alabaster 7 : Wool 15 : Crystal 80 : Oak 8 : Bronze 9 : Pottery


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Dignan Porch
London, UK
Est. 2009
Hailing from South London's Tooting neighborhood, Dignan Porch began as the lo-fi psych pop bedroom musings of Joe Walsh (not to be confused with the classic rocker of the same name), but soon became a full-fledged band featuring Walsh's guitarist brother Sam, bassist Ben Goodwin, and drummer Philippa Bloomfield. Walsh initially intended to call the project Porch but added Dignan to the name after a friend's dog. The band released its first single, the 90-second "On a Ride," in 2009; the single caught the attention of Captured Tracks, who discovered Dignan Porch via MySpace and signed them, releasing their debut album, Tendrils (which was based largely on Walsh's eight-track bedroom recordings) in early 2010. For 2011's Deluded EP, the band recorded with Henry Withers and added keyboardist/vocalist/visual artist Hayley Akins and drummer Stephen Keane to the fold, both of whom contributed to the EP's more polished, fleshed-out sound. The band's second full-length, Nothing Bad Will Ever Happen, was recorded live with minimal overdubs and released in August 2012. For the band's relatively spare third album, Observatory, which was recorded in Walsh's apartment above a used carpet store, Dignan Porch moved to the London imprint Faux Discx.


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Can you advise me the best fillers to use for fairly deep lines?
Doctor Answers 5
Best fillers for deep lines
Filling lines or correcting the cause of the lines?
Simply "chasing the line" is usually not the best solution. Replacing volume in the areas that are deficient can restore both the fullness you had when you were younger and also help alleviate the lines and wrinkles. Remaining wrinkling can be addressed at that point.
Sculptra is still the most capable product for restoring age-related volume loss as it induces new collagen production. There is a new volumizing filler, Voluma, that is great for the cheekbone area and the chin.
Belotero will make a good finishing touch for fine lines.
Learn more: http://rebeccafitzgeraldmd.com/sculptra.html
Filler Treatment
You might also like...
Deep lines to fill
Deep lines to fill usually require a combination of fillers to restore lost volume. Injecting Restylane or Juvederm will give you an immediate filling in areas such as your nasolabial area. Sculptra is ideal if you are trying to replace lost volume in the mid-face and temples. Belotero is a fine hyaluronic acid filler. It is idea for fine lines such as around the mouth and for the under eye area.
Learn more: http://www.michelegreenmd.com/belotero-balance
Volumizers for Deep Lines
Belotero is a thin hyaluronic acid used in the superficial tissue to fill fine lines. This product would not be used to correct deep folds or lines. Usually, a thicker, more cohesive product is injected deeper in the dermis or directly on the bone for volume. One may then layer products and treat superficial with a product such as Belotero. This will give a beautiful result. Voluma is a product recently marketed by Allergan. It is a hyaluronic acid such as Juvederm, Belotero, Restylane and Perlane but, it is the first FDA approved product recommended for mid facial volume loss. Studies show that Voluma remains up to two years after optimal improvement has been met. I would also continue the Botox, as you have in the past.
If I can be of further assistance, please contact my office. I will be glad to help you.
These answers are for educational purposes and should not be relied upon as a substitute for medical advice you may receive from your physician. If you have a medical emergency, please call 911. These answers do not constitute or initiate a patient/doctor relationship.