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Tuesday, June 24, 2014
Turmeric Curcumin - C3 Complex, with Bioperine #Curcumin
Turmeric Curcumin is one of the must have supplements! People use Turmeric for cooking, but now people are using it for their health. There has been many studies done on how Turmeric has improved many medical conditions. Turmeric has been traditionally used for centuries, by Ayuvedic and Chinese medicine. Curcumin is the most powerful anti-inflammatory compound in Turmeric. Turmeric has been used for its anti-aging benefits. Curcuminoid Polyphenols is the antioxidant in Turmeric Root.
Nutraviva Turmeric CurcuminFor this review, I received one bottle of Turmeric Curcumin - C3 Complex, with Bioperine! I know that Turmeric is an excellent supplement and it can help improve your health. I've research turmeric for sometime and I created a couple of Pinterest boards called, Turmeric/Curcumin/Cayenne Pepper/Curcuminoids and Cancer/Turmeric/Curcumin, where I continue to add more pins that are linked to turmeric and what it'll do for the body. If you look at the list below, it's quite impressive! At the bottom of the list, I'll leave links to the articles of where I found this information.
Here are a number of health benefits that Turmeric has been know to help:
- Blood Sugar Imbalances
- Insulin Resistance
- Destroys Cancer Cells
- Harmful Bacteria
- Bad Cholesterol
- Inflammation
- Ease Arthritic Pain
- Slows or Delays Liver Damage
- Slows or Helps Reverse Alzheimer's Disease
- Help Prevent the Early Manifestation of Parkinson's Disease
- Aids in Digestion
- Helps Heal Inflammatory Bowel Disease
- Promotes Heart Health
- Boost the immune System
Sources: Natural News
Discover the amazing ability of curcumin (turmeric) to fight chronic disease
Curcumin slays cancer cells in their tracks
The powerful health benefits of curcumin
Six ways turmeric heals your overburdened body
Curcumin found to prevent brain degenerative diseases including Parkinson's and Alzheimer's
New hope for liver disease: curcumin in tumeric spice fights liver damage and cirrhosis
This Turmeric Supplement is enhanced, with Bioperine for Greater Absorption and Bio-availability. Bioperine is an extract from black pepper, which has been used in Ayurveda medicine. Bioperine has been clinically tested in the United States and has been shown to significantly enhance the bio availability of nutrients, by increasing their absorption. Just think how the Bioperine, increases the absorption of Turmeric and how it can help you to absorb other nutrients.
Here's the label, from the bottle of Turmeric Curcumin. I love the fact that it does NOT have any stearates, silicone dioxide, fillers preservatives, artificial ingredients or binders! It's hard to find supplements that do not have any magnesium stearate in it. Magnesium Stearate is a flow agent additive that, over time can actually block the absorption of nutrients into your body and regular consumption of it is linked to the development of a harmful "biofilm" in the intestines that may cause digestive problems. So, always read your labels, especially on supplements!
Disclaimer: Information on this site is provided for information, educational and entertainment purposes only. It is not meant to substitute any advice provided by your own physician or other medical professionals of any kind. You should not use the information contained herein for diagnosing or treating a health problem or disease. Results may vary among users. The products and the claims made about specific products and information contained on or in any product label or packaging on or through this site have not been evaluated by the Food and Drug Administration and are not intended or approved to diagnose, treat, cure, or prevent any disease. Quick Tattletails assumes no responsibility for the use or misuse of this material. I am not a chemist, doctor, nor do I have any type of medical degree. My reviews are based on my opinion and they may not be actual facts. This post may contain links to other websites and Quick Tattletails is not responsible for any content on those websites.
I received one or more of the products mentioned above for free using Tomoson.com. Regardless, I only recommend products or services I use personally and believe will be good for my readers.
Posted by Bonny Sallee at 6/24/2014 12:39:00 PM
Labels: Herbs, Reviews, Supplements, Turmeric
Subscribe to: Post Comments (Atom)


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Angels With Creamy FacesFavorites [+]
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Running Time: 122 minutes
Released: 03/2015
Studio Name: Gothic Media Sunset Media Evil Playgrounds
Director: Dimitri Ziua
Categories: Euro International All Sex High Definition
Description: Hot Russian Babes love nothing more than to drip with bucketloads of cum!
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Keep yourself warm while the Denver Broncos are heating up the field in this Nike Gold Collection KO performance hoodie with Therma-FIT technology!
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Children's cookery courses run at our base near Winchester in Hampshire
Children's Holiday Classes
We run a variety of one-off cookery events in the school holidays and occasional Saturdays. These classes are aimed at younger cooks and teenagers. We also run 'Student Survival' workshops for those young people heading off to uni or college for the first time and who need to learn some basic cookery techniques and recipes.
All of the classes are small to ensure that the children get as much help as they need depending on their age and ability. We do maintain a waiting list so please get in touch if you were unable to secure a place. If there is sufficient demand, we may run the programme on another day of the week.
Children's Birthday Parties
How about hosting a cookery party for your child? Cupcake decorating for example is always popular and an opportunity for your child and their guests to get really creative. We can bring the cakes to your home along with all the necessary equipment and decorations.
For details of this and other cookery parties, along with pricing, please contact us directly. Contact Page
Safeguarding - All sessions are run by Clare who has been cleared to work with children by an enhanced DBS check. She also holds a certificate in food hygiene and nutritional qualifications.
It's never too early for children to learn to cook.


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GUILFORD – Muriel I. Herring, 88, died July 30, 2012, at Hibbard Nursing Home, Dover-Foxcroft. She was born June 25, 1924, in Dover-Foxcroft, the daughter of Waldo and Doris (Mason) Lary.
She graduated from Sangerville High School, class of 1943, and from nursing school in Biddeford in 1946. After graduation she worked as a registered nurse doing general duty nursing at Mayo Regional Hospital, Dover-Foxcroft. She was an active member of Abbot Evangelical Free Church. Her great passions in life were her Lord and Savior, and her family.
She was predeceased by her husband, H. Erland Herring, in 2002. She is survived by two daughters and their husbands, Brenda and Roger Ronco and Cheryl and Pat Bush; a sister, Marilyn Cookson, all of Guilford; five grandchildren, Scott and Kevin Ronco, Amy Stillman, Kimberly Dunham and Ryan Bush; 14 great-grandchildren; and a nephew, Ronnie Cookson.
Friends may call 6-8 p.m. Thursday at Crosby & Neal, 21 Oak St., Guilford. Graveside services will be held 11 a.m. Friday, Aug. 3, at Village Cemetery, Sangerville, with Pastor Ray Beless officiating. In lieu of flowers, donations may be made to Abbot Evangelical Free Church, P.O. Box 131, Abbot, ME 04406. For an online guest register, go to www.CrosbyNeal.com.


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28' Marinette Sport Cruiser 1979 Yacht for Sale
Yacht Broker Name:
Dennis Demole
Broker Phone Number:
Marinette Sport Information:
- 28 Marinette 1979 Sport
- Vessel Name:
- Vessel Length: 28 feet
- Vessel Builder: Marinette
- Vessel Model: Sport
- Vessel Year: 1979
- Vessel Type: Cruiser
- Vessel Price: $ Contact for Price
- Vessel Location: Merritt Island, FL US
- For additional details please scroll down
Get More Info:
28 Marinette Sport 1979 Details:
Vagabond is a great example and well taken care of 1979 Marinette 28' Cabin Cruiser built by Aluminum Cruisers, Inc. in Louisville, KY. Bimini covered aft deck, walk through glass slider into salon and helm area, two steps down to dinette and galley area, dinette drops down for berth, galley has 2 burner electric stove, sink, refrigerator under sink storage and drawers, full head port side, fresh water flush toilet, shower and sink, forward V-Berth. Nice layout with good room in cabin. Classic lines outsides keep this vessel looking crisp and well appointed. High stainless steel bow rail encompasses port and starboard walkways to bow. Clean well-kept and ready to go.
Other interesting yachts for sale


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Welcome to Green Point Cricket Club.
A Proud Club
Green Point Cricket Club has a proud history of being one of the top clubs in Cape Town. The club was founded back in the 1890's and is one of the oldest cricket clubs in South Africa. We are still to this day primarily a cricket club with 4 teams taking part in the Western Province Leagues. We have however evolved over the years and added activities such as Social Squash and a gym facility to our Senior and Junior cricket offerings. Situated in the beautifully picturesque area of the Green Point common and in the heart of the Atlantic Seaboard, we also offer a great facility to the people living in the area, many of which make use of our facilities for dog walking and events.
We have a long history of having members from all races, cultures and backgrounds. We are proud that we were the first "white" cricket club in Cape Town to open its doors to members of all races.
Fantastic Facilities
Green Point Cricket Club have fantastic facilities which include four grass nets, six artificial nets and two playing fields. We cater for players at all levels.
Green Point Cricket Club currently have two squash courts which are used daily by our social squash members.
Gym Facility
The Gym is a small facility but caterers for your every need. you will also have our local friendly Bio-kineticist, Sean, who is at hand to help out with any of your needs.
Dog Walking
Green Point Cricket Club provides it's facilities to dog walkers in the area that are looking for a secure space to run their pets. All that is required is that you become a member of the club and for this nominal annual fee you will have a space to do this.
The clubhouse and facilities are also a great event or function venue. Whether it be an indoor or outdoor event, this is the perfect place to host it in the Green Point area.
Sign Up
Anyone is welcome to join up at any stage of the season and we are always looking for new members. Dust off the kit and come join us at a practice. Hope to see you soon.
Contact Us
Feel free to contact us.


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- Powered from 9V Battery or Regulated power supply
- Traditional Wah Wah sound (without the crackle)
- Rich warm harmonic content
- Minimal adjustment
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- Economically priced with unbelievable performance
- Ideal for both Guitars, Bass and other instruments
- (2012-04-17) DAPHON WAH PEDAL by facelessnomore
- (2014-09-14) Daphon DF2210 Wah-Wah Pedal by intheblues
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|Property type
|Minimum Stay
|3 nights
We built this beautiful 1500 sq. ft. cabin for our own personal getaway. We like high places so the cabin is on the side of a mountain at 8000 ft. elevation with a panaramic view of the Big Horn Mts, the highest being Cloud Peak at 12,223 ft. The sun rises behind the cabin which provides an amazing light show on the peaks in front of the cabin and sets over the Hazelton Peaks at the left front of the cabin's 16x20 deck for a truly one of a kind sunset. The show is not over yet because at this elevation with no other lights around the stars are so crystal clear and brilliant. The view from the porch or the big picture window in the living room is a never ending enjoyment day or night.
The Cabin has a king size bed in the master bedroom,double bed in other private bedroom and 2 double beds in the loft. The Kitchen is fully equipped to do any kind of cooking that suits you and there is a large oak table with 8 chairs .The livingroom is equipped with a beautiful red Vermont Casting wood stove, a leather couch with 2 recliners, leather love seat w/2 recliners, and a large leather recliner. There is also a 32' LCD flat screen TV with dvd player so you can watch your favorite movies. The walls and ceilings are all Aspen finished and there are hard wood floors throught out.
The cabin is perfect place for early risers to sit on the deck, enjoy your morning cup of coffee and watch nature unfold as the sun rises. You never know what you might see before you.
This is an ideal location for snowmobilers, fourwheelers, hikers, and other outdoor enthusiasts as it borders the National Forest on the front and BLM on the back. Your fun is only limited by you.
Keywords: Cabin, Big Horn Mountains, 23 acres, joins National Forest in Front, BLM in back. Breathing view
Cancellation policy:
Please fill out, sign and return the rental agreement. Once it and payment have been received you will be given instructions on entry to the property. You may fax your agreement (307-684-0157) or mail it (Al Weeden, P.O. Box 1040 Buffalo WY 82834.) Thanks for choosing us for your vacation rental! SHORT TERM RENTAL AGREEMENT This Short Term Rental Agreement is made by and between Elk meadow Cabins and ______ _____________ (Guest) as of the date last set forth on the signature page of this Agreement. For good and valuable consideration, the sufficiency of which is acknowledged, the parties hereby agree as follows: This property is located at 334 Billy Creek Road, Buffalo WY 82834. The property is furnished and includes linens, towels, refrigerator, stove/range, microwave, toaster, coffee pot, DVD player, and TV. The rental party shall consist of _______________________ (guest) and the following persons: ______________________________________________________________________________ The maximum number of guests is limited to 8 persons. The lease begins at 3:00p.m. on ___________(check-in date) and ends at 12:00p.m. on ___________ (check-out date.) This property does require a minimum stay, of a 3 night stay. Guest agrees to abide by the Rental Rules attached as Exhibit A at all times while at the property and shall cause all members of the rental party and anyone else the guest permits on the property to abide by the following rules at all times. Guest shall allow Homeowner access to the property for purposes of repair and inspection. Homeowner shall exercise this right of access in a reasonable manner. Payment and Fees: a. A deposit of 50% of the total is due immediately. B. Tax is 7% C. Cleaning fee of $150.00. D. Damage insurance $69.00 non refundable. E. The remaining balance is due 30 days before check-in date. If the premises appear dirty or damaged upon Check-in, Guest shall inform Homeowner immediately. Cancellation Policy: If Guest wishes to cancel his/her reservation, the deposit will be refunded as follows: 100% if cancelled 60 days prior to the Check-in Date. Although it is not required, we encourage all renters to purchase traveler insurance. Payment: Acceptable payment methods are credit card. By my signature below, I agree to all payment policies and that all rental monies are non-refundable per cancellation policy above. I have read my rights to purchase travel insurance. I agree to abide by the rental rules as set forth in Exhibit A. The parties agree to this Short Term Rental Agreement, as evidenced by the signatures set forth below. Homeowner: and Jane Weeden, Elk Meadow Cabins ________________________ Date:_____________________ Phone # during stay: 307-217-0993 or 0995 ; Guest: ___________________________ Name (print): ______________________ Date: ______________________ Phone # during stay: _______________________ Exhibit A Rental Rules 1. Smoking is NOT allowed 2. People other than those in the Guest party set forth above may not stay overnight in the property. Any other person in the property is the sole responsibility of the Guest. 3. All of the units are privately owned; the owners are not responsible for any accidents, injuries or illness that occurs while on the premises or its facilities. The Homeowners are not responsible for the loss of personal belongings or valuables of the guest. By accepting this reservation, it is agreed that all guests are expressly assuming the risk of any harm arising from their use of the premises or others whom they invite to use the premise. 4. Keep the property and all furnishings in good order. If you move furnishings please put them back where they were originally before checking out. 5. Only use appliances for their intended uses. 6. Pets are NOT allowed. 7. Parking: Parking is limited to 4 vehicles. Vehicles are to be parked in the driveway/graveled area and/or on the road in front of the house. Any illegally parked cars are subject to towing; applicable fines/towing fees are the sole responsibility of the vehicle owner. 8. Housekeeping: There is no daily housekeeping service (unless prearranged with the homeowner.) While linens and bath towels are included in the unit, daily maid service is not included in the rental rate. We suggest you bring beach towels. We do not permit towels or linens to be taken from the units. 9. Storms: If there is a winter storm, you will need to use snowmobiles or other forms of snow travel to get in to cabin. We highly recommend four wheel drive and/or chains during the snow months or snowmobiles. 10. Do not leave children unattended 11.The property on either side of the cabin is private property stay off of there property. Thank you! We hope you have a pleasant and safe vacation!
100% refund if canceled at least 60 days before arrival date.
|Rate Period
|Weekend Night
My Standard Rate
3 night minimum stay
|Notes: Rates are based on 5 guests; add C$63 per night, per additional guest
|C$188.08 + Tax
|extra guests over 5
|C$62.69 + Tax
|Tax Rate


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Mid-range cymbals featuring Swiss craftsmanship at an economical cost.
Crafted from the legendary 2002 bronze, PST 8 cymbals by Paiste are refined through traditional hand-hammering and perfected with the unique handmade Reflector finish. These hallmarks of Swiss workmanship make these cymbals pure Paiste instruments, yet they are as attractively priced as the other successful Paiste Sound Technology series.
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Order today!
Our product catalog varies by country due to manufacturer restrictions. If you change the Ship-To country, some or all of the items in your cart may not ship to the new destination.


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Nice photo !
Its really feel like Ballad under the water, really beautiful shot
It was a load of fun to shoot.
It was a load of fun to shoot.
Well! i really hope to see more excellent work like that frm U so keep on shooting great shots
You have really found your passion...in this under water world of photography......
I really love this, it gives off this kind of dark ballerina vibe or something. But there's also a strong sense of beauty and mystery to it while it shows off a very delicate nature as well. Good Job.
omg! WOW!
lovely picture, very delicate.
AMAZING you really have an eye for photography!! LOV IT!
That is amazing!
Wow, did she really stand like that?
sO nice!!!
Adele - Rolling in the deep (Villa Remix) - this song stuck in my head.. I like remix, my advise)
I don't like remixes xP
Although, linkin park made a great cover to it.
Although, linkin park made a great cover to it.
Amazing !
This is beautiful. It's one of those shots that while being technically still and colorless has motion and color of its own
there`s A , starting in my
reaching out fever-pitch
& just bringing me out the dark,
finally I can see you crystal clear...
addictive song!
No freaking lie!
I couldn't stop singing it yesterday, my throat started to hurt x.x
I couldn't stop singing it yesterday, my throat started to hurt x.x
This is amazing!
My favourite song in the moment
Nice work and good photography!
Nice work and good photography!


text:
J.R.R. Tolkien provided beautifully sketched maps of the world he created for his stories. Slippery Rock University geography professor Stentor Danielson has taken that drawing style and applied it to modern cities creating maps that look like they were torn from the pages of Tolkien's books. He's already got Boston, Pittsburgh, Cleveland, Washington, DC, and more, all available as prints to decorate your home.
See more maps after the break.
Product Page ($23 via io9)


text:
Company Description
Stag Engineering Nigeria Limited is a leading wholly Nigerian owned engineering firm in Nigeria. The company has over 40 years experience in providing expert engineering services and mercantile power to discerning clients in Nigeria and West Africa. At present it delivers over 1,000MW of mercantile power to these clients. The company has recently expanded into the marine and will be expanding its expertise to railway solutions in 2013.
Job Title: Sales Manager
Job Qualification
HND, BSc, BA
Job Experience
10 Years
Job Location
Job Category
Engineering, Technical
Method of Application
Applicants should send their CVs and applications with copies of their credentials to firstname.lastname@example.com using the job title as the subject of the mail
Closing Date
Not Stated
Share this job now with your friends on Facebook, Twitter, Linkedin......Latest, most current jobs in Nigeria
Wednesday, 18 May 2016
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text: This Creepy Clown is casually leaning against a lamp post, the light flickering, then raises the balloon to his mouth and begins to blow the huge balloon up. When the balloon obscures his face, his head turns 280 degrees and suddenly, the Clown turns creepy! As the balloon is lowered, guests are hit with a blast of air. Includes lamp post with flickering light, costumed animated clown and an extra supply of balloons. Operated by included switch or with motion sensor, pressure pad or timer box. 100-125 psi air compressor and AC power required. Clown faces shown in photo may vary. DIGITAL SOUND for Creepy the Clown $450.00.


text:
Scott Redler, the Chief Strategic Officer for T3Live.com, and Brittany Umar discuss how investors are handling the slipping Japanese yen (FXY and YCS), the S&P highs (SPY), and look at the charts of several banks including Citigroup (NYSE:C) and a few Internet companies including eBay (EBAY), Yahoo (YHOO), and Amazon (AMZN), and take a quick look at Apple (AAPL).
In addition to the Main Virtual Trading Floor(R), T3Live offers four Mentoring Rooms based your desired time frame for trading. Take a 5-day free trial to any of our mentoring rooms and see which one is right for you.


text:
Callum Vincent Squibb vs Justin Bieber LOL!!!!
25th June 2012 - 8:37 | London UK, North London
Callum Vincent-Squibb > Your fault, you always wanted justin beiber and pushed me away:'( now I'm gone from your life forever, not moving to canada with you, no cuddling when watching a horror film, no protecting you from everything, I'm gone now :/xxxxxxxxxx
Sophie Jones> Aww no I'd rather have you({})xxxxxxxxxxxxx
Callum Vincent-Squibb > Aww that's nice but you already chose justin beiber so that's who you
Sophie Jones> No I was joking really, I bet justin biebers got really crappy hugs aswell!:(xxxxxxxxxxxxxx
Callum Vincent-Squibb > Well I guess you'll find out soon, you chose him so you get his hugs, I'm dead now, there is no callum, you only have justin beiber, I'm sure you'll be fine=D>:/xxxxxxxxxxxxx
Sophie Jones> No I'll miss you:o:oxxxxxxxxxxxxx
Callum Vincent-Squibb > Well its too late now, should have thought about that when you kept asking for justin beiber:Oxxxxxxxxxxxxx
Sophie Jones> I don't want him tho:(xxxxxxxxxxxxx
Callum Vincent-Squibb > Well clearly you did, you asked for him loads of times!:(xxxxxxxxxxx
Sophie Jones> I was joking:(<3xxxxxxxxxxx
Callum Vincent-Squibb > You weren't joking, you wanted him and I warned you that your gonna get him if you
keep asking, but you carried on asking so you clearly wanted him! Now you realise who's better you don't want
him anymore but your too late:Oxxxxxxxxxxxxxx
Sophie Jones> :'(:'( xxxxxxxXxxxxxx
Callum Vincent-Squibb > How do you think I feel?:O:(xxxxxxxxxxxx
Sophie Jones> ;;) I'm sorry:*xxxxxxxxxxxx
Callum Vincent-Squibb > Sorry doesn't bring me back :O you can't have me now!=Dxxxxxxxxxxxxxx
Sophie Jones> :'( xxxxxxxxxXxxx
Callum Vincent-Squibb > Unless your willing to do a swap and never speak of justin beiber
Sophie Jones> Yes!xxxxxxxxxxxx
Callum Vincent-Squibb > But then your stuck with me forever!:Oxxxxxxxxxxxxxxx
Sophie Jones> Good;;) xxxxxxxxxxxxx
Callum Vincent-Squibb > Stuck with my badlooks and bad body a little penis =D:'(=))xxxxxxxx
Callum Vincent-Squibb > xxxxxxxxxxxxxxxxxx*
Sophie Jones> You're good looking&youve got a nice body so sh, and I can't comment on the last
Callum Vincent-Squibb > I'd be worried if you can=Dxxxxxxxxxxxxx
Sophie Jones> X_X don't worry=dxxxxxxxxxxxxx
Callum Vincent-Squibb > Hahahahah=D I reckon you might see it when we move to canada though=D;)xxxxxxxxxxxxx
Sophie Jones> =D Xxxxxxxxxxxxx
Callum Vincent-Squibb > Well you picked me so you will have to see it at some point :O unless you want justin
beiber back?:O=Dxxxxxxxxxxxxxxxx
Sophie Jones> Thought we weren't allowed to say his name:O xxxxxxXxxxxxxxx
Callum Vincent-Squibb > We ent but this once is allowed, last chance, you can have him back if you
Sophie Jones> No;;) Xxxxxxxxxxxxx
Callum Vincent-Squibb > Well that means you've picked that you wanna lose your v to a british person unless
you don't wanna lose it at all:O=Dxxxxxxxxxxxxxx
Sophie Jones> Can I go sleep yet?(=|xxxxxxxxxxxxx
Sophie Jones> Haha course I do=dxxxxxxxxxxxx
Callum Vincent-Squibb > You can go sleep whenever you want, don't have to listen to me:( and haha well guess
who's taking it then?=D unless you wanna change what british person you want it to be?=))xxxxxxxxxxx
Sophie Jones> I do incase your lonely;;) but you've confused me now=dxxxxxxxxxxxxx
Callum Vincent-Squibb > Basically a british person is taking your v =D and atm when we move to canada I'm the
only british one that ent family so I'm taking it =D unless you wanna change the british person you take on
holiday, I would if I was you, look at me=dxxxxxxxxxxxxxxx
Sophie Jones> Yeah you're good looking!xxxxxxxxxxxxxx
Callum Vincent-Squibb > So wanna change the british person then?=Dxxxxxxxxxxxxxx
Sophie Jones> Sweet dreams!:*xxxxxxxxxxxxxXx
Callum Vincent-Squibb > You too sweetie!:*xxxxxxxxxxxxx
Sophie Jones> Hehe;;):*xxxxxxxxxxXxx
Callum Vincent-Squibb > ;;):*xxxxxxxxxxxxxxxxx
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text:
The cross talk for image plane holograms is calculated and compared with previously derived results for Fourier plane holograms. Image plane storage is found to have significantly smaller cross talk.
© 1994 Optical Society of AmericaFull Article | PDF Article
OSA Recommended Articles
Kevin Curtis, Claire Gu, and Demetri Psaltis
Opt. Lett. 18(12) 1001-1003 (1993)
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Opt. Lett. 20(7) 779-781 (1995)
Jung-Ping Liu
J. Opt. Soc. Am. A 28(2) 229-237 (2011)


text:
Gary the Gadget Guy gave elite agents a new message through the EPF Messaging System telling us we are doing well protecting the island from Herbert P Bear and Ultimate Protobot. This was his message:
Gary the Gadget Guy said:
"Good work this week agents. We can now track some of Herbert and Protobot's secret messages. Stay on alert."
This week? It's Friday. No more tasks for us this week. Take a break agent.
-Andreylaur, Blog Owner


text:
The Crap We Missed – Tuesday 3.20.12
A pile of dog shit.
"Oh, my ankles are showing! Better nip that in the bud, lest I seem like an exhibitionist!"
If i really had to, I would take that home with me. The canine, not the woman,
Is that her femur poking through her pants?
Dammit! I wish the tampons would quit s.lipping out.
Dammit! I wish the tampons would quit slipping out.
The dog's face says it all
think both dogs should reverse the leash..
Awesome, I've never seen an old lady's fake titties before. No joke, your mom's are unspectaculary real. But you knew that.
Yeah, so flashing TV land is no big deal, but heaven forfend your pants cuff be a little out of place.


text:
While iPhone competitors have come and gone (HTC and BlackBerry come to mind), Samsung has actually been able to garner significant marketshare and provide an attractive alternative to the iPhone in the form of its wildly popular series of Galaxy S smartphones.
Not only has Samsung been able to offer a moderately compelling user experience (one which Apple thinks borrows too heavily from its own), but it has also been able to differentiate its products from the iPhone by offering devices at a variety of pricepoints and, of course, with much bigger screens.
Tomorrow, Samsung will be taking the wraps off its latest smartphone, the Galaxy S IV. And for the first time, Samsung will be unveiling its latest and greatest smartphone not in Seoul, South Korea, but smack dab in the middle of New York City at Radio City Music Hall, just blocks from Apple's flagship Apple retail store. What's more, Samsung will be broadcasting the event live in Times Square.
Suffice it to say Samsung has been rather shrewd when it comes to marketing, and now it's taking the fight right over to Apple's turf.
The Galaxy S IV won't include eye-scrolling technology as previously rumored, but it will come with a 5-inch screen, a 13-megapixel camera and a quad-core processor from Qualcomm. From a Bloomberg article:
The timing of the S4's arrival could spell trouble for Apple, which probably won't have a new phone out until mid-year at the earliest, said Park Hyun, an analyst at Tong Yang Securities in Seoul. Apple's sales growth last quarter was the slowest in more than two years, a sign the iPhone is losing its edge over other smartphones.
"Its popularity has clearly cooled off," Park said. The next Apple phone, expected to be called the iPhone 5S, will be out in the late second quarter or early third quarter, he said.
Now, I wouldn't say that the iPhone's popularity has cooled off seeing as Apple continues to sell tens of millions of iPhones each and every quarter, but there's no denying that Samsung's range of smartphones is really establishing its own niche within the market. Apple's marketing efforts may downplay the benefit of a wider screen, but there's clearly a large contingent of users out there who prefer a larger, more vibrant display.
The main takeaway from Samsung's venture into NYC is that the company has learned from the master. The release of the Galaxy S IV is an event that has people buzzing, and is one of the top stories across the tech blogosphere. And all of that attention for a product that likely won't be that different from the Galaxy S III. That's an impressive feat for any company not named Apple to pull off.
via Bloomberg


text:
All of the attendees
Marcy, Grace & Syreeta
I met some new sewists. I made a date to go fabric shopping in Queens, cause y'all know I'm always looking for more places to fabric shop! *LOL* I touched some me-made garments and before I knew it, it was almost 8:30pm. 2.5 hours went soooooo fast!
Carol, Amanda, Lara & Claire
Kten & Marcy's curls
So this Tuesday, July 25th, we will be meeting again at:
The Houndstooth Pub
820 Eighth Avenue
6pm - until
If you're in the NY, NJ, CT, PA area and want to spend an evening with other sewists talking about our favorite topic, come through! If you can't make it this Tuesday, then we will be there the last Tuesday of every month...come then...
...as always more later!


text:
Get an overview of this hotel3-star hotel with free breakfast and 24-hour front desk
Popular property highlights
Situated in Szekesfehervar, this hotel is within 1 mi (2 km) of Egyhazmegyei Museum, Garden of Ruins, and István Csók Gallery. National Memorial Place and Cathedral Basilica of Saint Stephen are also within 1 mi (2 km).
Hotel Features
This hotel features meeting rooms, laundry facilities, and a 24-hour front desk. Free buffet breakfast, free WiFi in public areas, and free self parking are also provided. Other amenities include a front-desk safe.
Room Amenities
All 60 rooms offer free WiFi, refrigerators, and TVs with cable channels. Other amenities available to guests include showers, phones, and desks.Information missing or incorrect? Tell us!Opens in a new window
Jancsár Hotel
Hotel Amenities
Hotel Amenities
A complimentary breakfast is offered each morning. Wireless Internet access is complimentary. This business-friendly hotel also offers a terrace, laundry facilities, and a safe deposit box at the front desk. Complimentary self parking is available on site.
- 24-hour front desk
- Total number of rooms - 60
- Number of floors - 3
- Free breakfast
- Elevator/lift
- Free WiFi
- Laundry facilities
- Meeting rooms 2
- Terrace
- Luggage storage
- Safe-deposit box at front desk
- Free self parking
- Number of buildings/towers - 1
Family Friendly Amenities
- Free Wi-Fi
- Laundry facilities
- Refrigerator
Available in all rooms: Free WiFi
Available in some public areas: Free WiFi
Free self parking
Room Amenities
- Phone
- Refrigerator
- Private bathroom
- Shower only
- Television
- Desk
- Blackout drapes/curtains
- Cable TV service
- Free WiFi
- Heating
Where to Eat
A complimentary buffet breakfast is served each morning between 7:00 AM and 10:00 AM.
Hotel Policies
Check-out time is noon
Payment types
Children and extra beds
- Children are welcome.
- Rollaway/extra beds are not available.
- Cribs (infant beds) are not available.
- Pets allowed for an extra charge of HUF 1500 per pet, per night
- Dogs only
You need to know
Extra-person charges may apply and vary depending on property policy.
Government-issued photo identification and a credit card or cash deposit are required at check-in for incidental charges.
Special requests are subject to availability upon check-in and may incur additional charges. Special requests cannot be guaranteed.
24-hour check-in
No rollaway/extra beds available
No cribs (infant beds) available
Optional extras
- Pet fee: HUF 1500 per pet, per night


text:
|Publication number
|Publication type
|Application number
|Publication date
|Jan 7, 1992
|Filing date
|Dec 4, 1990
|Priority date
|Apr 19, 1990
|Fee status
|Also published as
|Publication number
|Mark B. Knudson, James E. Shapland
|Original Assignee
|Inomet, Inc.
|Export Citation
|BiBTeX, EndNote, RefMan
|Patent Citations (36), Non-Patent Citations (4), Referenced by (64), Classifications (10), Legal Events (6)
|External Links: USPTO, USPTO Assignment, Espacenet
The present application is a continuation-in-part application of earlier filed and commonly assigned, copending U.S. patent application Ser. No. 07/510,935 filed Apr. 19, 1990 and entitled "INFRARED AND NEAR-INFRARED TESTING OF BLOOD CONSTITUENTS". The present application also discloses certain material which is claimed in concurrently filed and commonly assigned U.S. patent application Ser. No. 07/621,771 entitled "BLOOD CONSTITUENT MEASUREMENT". Both of the foregoing applications are filed in the name of Mark Knudson, one of the present co-inventors.
1. Field of the Invention.
This patent application pertains to an apparatus for testing blood constituents. More particularly, this application pertains to such an apparatus utilizing spectrophotometric analysis of blood constituents.
2. Description of the Prior Art
The use of spectrophotometric methods to quantitatively determine the concentration of a blood constituent are known. For example, Schlager U.S. Pat. No. 4,882,492 teaches a non-invasive near-infrared measurement of blood analyte concentrations. The Schlager patent is particularly directed to the measurement of blood glucose levels. The Schlager patent recognizes that certain wavelengths of light in the near-infrared spectrum are absorbed by glucose. Modulated light is directed against a tissue (shown as an earlobe). The light is either passed through the tissue or impinged on a skin surface. The light is spectrally modified in response to the amount of analyte (for example, glucose) in the blood and tissue. The spectrally modified light is split with one beam passed through a correlation cell. The other beam is passed through a reference cell. The intensity of the beams passing through the correlation cell and the reference cell are compared to calculate a glucose concentration in the sample.
Jobsis U.S Pat. No. 4,805,623 teaches a spectral photometric method for quantitatively determining the concentration of a component in human blood. The Jobsis method teaches various steps including the determination of an apparent effective path length for the light which is being absorbed by the constituent being measured.
Dahne et al. U.S. Pat. No. 4,655,225 teaches a spectrophotometric method and apparatus for non-invasive testing. The Dahne patent is particularly directed to the measurement of blood glucose.
March U.S. Pat. Nos. 4,014,321 and 3,958,560 teach non-invasive glucose sensor systems which involve passing light through the cornea of the patient.
Muller U.S. Pat. No. 4,427,889, dated Jan. 24, 1984, teaches a method and apparatus for molecular spectroscopy. In the embodiment described within the patent, blood glucose is determined through absorption analysis of infrared wavelengths absorbed in a glucose-containing sample (such as whole blood or urine).
Notwithstanding the developments in the art, a need for an improved spectrophotometric measurement apparatus and method persists. For example, systems and methods which require the calculation of an apparent light pathway are susceptible to inaccuracy. Such a system is shown in the aforementioned U.S. Pat. No. 4,805,623. Systems which have fixed dimensioned light pathways (for example, U.S. Pat. 4,014,321) are restricted in their use and practicality. It is also desirable to develop a system and apparatus which can be used for non-invasive testing as well as invasive testing (for example, as a continuous monitor for testing blood glucose level during surgery or insulin treatment). Further, it is desirable to develop a system which can be used in conjunction with a chemical emission system (such as a blood glucose monitoring system which controls an insulin administering apparatus).
In addition to the foregoing, it is desirable to provide an apparatus which can perform multiple wavelength analysis (i.e., broad spectrum analysis) of a sample. A common technique for providing a broad spectrum analysis is a so-called Fourier transform infrared ("FTIR") spectrometer. Such spectrometers are well known in the art and include means for generating a beam of a source light. The beam is then split by a beam splitter into a reference light and a test light. The reference light is reflected off of a fixed mirror to a light detector. The test light is passed through or reflected from a sample and off a moving mirror. The moving mirror translates the information from the frequency domain to the time domain to produce an interferogram. When psssed through the sample, various frequencies of the light are absorbed at various rates depending upon the constituents of the sample. The light from the reflected test beam is directed to the light detector where it crosses paths with the reference beam. The modified test beam and the reference beam interact to form an interference pattern which is detected by the light detector and processed through a processor to generate a signal indicative of the constituents in the sample.
The use of Fourier transformed infrared spectrometry (FTIR) in testing for blood constituents (such as blood glucose) is known. A description of such a test is described in a paper entitled "Determination of Physiological Levels of Glucose in an Aqueous Matrix with Digitally Filtered Fourier Transform Near-Infrared Spectra" by Mark A. Arnold and Garry W. Small of the Department of Chemistry, University of Iowa, Iowa City, Iowa, as published in Analytical Chemistry, Vol. 62, No. 14, July 15, 1990.
In prior FTIR analysis, the test sample (such as a volume of blood) would be removed from a patient and placed on a FTIR spectrometer. As a result, the test was invasive as well as non-continuous.
It is an object of the present invention to provide a technique for using FTIR spectrometry to test for blood constituents in a manner which can be both continuous and non-invasive.
According to preferred embodiment of the present invention, an apparatus is disclosed for determining a level of a constituent such as glucose in a body fluid such as blood. The apparatus includes FTIR spectrometry utilizing a chamber having a movable membrane.
FIG. 1 is a schematic representation of an apparatus of showing its use in an embodiment for measuring a constituent within tissues, tissue fluid and blood in a tympanic membrane;
FIG. 2 is a view of an apparatus for use in invasive testing for blood glucose;
FIG. 3 is a schematic view of a system using the apparatus to control admission of a drug to a patient; and
FIG. 4 is a schematic view of an apparatus according to the present invention for use in measuring a constituent in a tympanic membrane where the tympanic membrane is utilized as a moving mirror in an FTIR spectrometer arrangement; and
FIG. 5 is a view of an invasive FTIR system.
Referring now to FIG. 1, an apparatus is shown for use in non-invasive testing for a particular body fluid constituent--namely, blood glucose. Also, in FIG. 1, the apparatus is shown in use for measuring glucose in body fluid in a tympanic membrane. While the illustrated application is a preferred embodiment, it will be appreciated that the salient features are applicable to a wide variety of body constituents. For example, glucose as well as other body constituents could be measured in a plurality of body fluids such as blood, interstitial fluid, crevicular fluid, and peritoneal fluid.
In FIG. 1, the apparatus 10 is shown in use for measuring glucose within body fluid in of a tympanic membrane 12 in a human ear 14. (The apparatus 10 is also suitable for veterinary uses.) In the embodiment now being described, the apparatus 10 is non-invasive (i.e., no penetration of body tissue is required).
The apparatus 10 includes a distal end which carries a speculum 16. Speculum 16 is preferably disposable and is sized to be received within the auditory canal 18 of an ear 14. The speculum is selected to block the auditory canal 18 to prevent ambient light from entering the ear past the speculum 16. Accordingly, the speculum 16 closes the auditory canal 18 to define a closed testing volume 19 between the speculum 16 and the tympanic membrane 12. The actual distance D between the source of light in the speculum 16 and the tympanic membrane 12 will vary with each use of the apparatus 10. However, as will be more fully described, the apparatus 10 includes means for measuring the distance D.
For reasons that will become apparent, the speculum 16 has a tip 20 which opposed the tympanic membrane 12 upon insertion of the speculum into the auditory canal 18. The tip 20 is selected to pass certain predetermined light wavelengths (e.g. wavelengths which are absorbable by constituents which are to be measured).
In a preferred example of measuring glucose within the tympanic membrane 12, the tip 20 is selected to pass infrared and near-infrared light wavelengths. It will be appreciated that a speculum such as speculum 16 having an infrared and near-infrared transparent tip 20 is known in the art. An example of such is shown in U.S. Pat. No. 4,662,360. Such prior art speculums have been developed for use with tympanic thermometers. The speculums of such thermometers would be inserted within the auditory canal and would permit infrared radiation generated by a tympanic membrane to pass through the tip of the speculum toward infrared radiation detecting apparatus contained within the speculum. With such prior art apparatus, a healthcare provider can measure body temperature by detecting infrared radiation emitted from the tympanic membrane. Examples of complete apparatus for measuring body temperature from the tympanic membrane are shown in U.S. Pat. Nos. 4,602,642; 3,949,740; 3,878,836 and 4,790,324.
The present technique contemplates the generation of a testing light which includes a wavelength absorbable by the constituent to be measured (for example, blood glucose). Shown schematically in FIG. 1, the system includes a generator 22 of broad band light sources including near-infrared and infrared light sources. Generator 22 may be a lasing diode or a broad band light source with filters.
The generator 22 is selected to generate a testing light of known intensity which includes a wavelength absorbable by the constituent to be tested. The generator 22 also includes means for generating one or more reference lights of known intensity having a wavelength(s) which is not absorbable by the constituent to be measured. Also, for reasons that will be described, the generator 22 includes means for generating infrared radiation of a heating wavelength selected to be directed for the purpose of warming and controlling the temperature of the tympanic membrane 12 and volume 19.
A waveguide 24 (e.g., a fiber optic cable or light directing tube) is passed from the generator 22 into the speculum 16 to be directed toward and oppose the tympanic membrane 12 upon insertion of the speculum 16 into the auditory canal 18. An alternative to using waveguide 24 would be for the generator 22 to be a light source (e.g., a diode or a tungsten filament) within the speculum 16.
The reader will note that the wavelengths of the testing light, the reference light and the infrared heating radiation will all be passed by tip 20 toward tympanic membrane 12. In the preferred embodiment, the testing light will include a glucose sensitive wavelength in a region bounded by approximately 500 to about 4000 wave numbers (cm-1). The non-absorbable reference light will have a preferred wavelength in about the same wavelength range (e.g. an absorbable wavelength in the range of 1030-1050 wave numbers and a non-absorbable wavelength of about 1150 wave numbers).
If it is desirable to test for constituents in addition to glucose, the generator 22 is simply selected to generate additional wavelengths selected for their absorbability by the desired constituent. In the schematic representation of FIG. 1, three optical paths 25-27 are shown for directing the infrared and near-infrared radiation toward the tympanic membrane 12. In a preferred embodiment, all light signals will be passed through a waveguide 24 with the light signals detected at a single detector.
Including being coupled to light generator 22, the speculum 16 is coupled with a distance signal generator 28. Distance signal generator 28 includes means for generating a signal for use in measuring the distance D from the speculum 16 to the tympanic member 12. In one embodiment, the distance signal generator 28 is an ultrasonic generator which will measure the distance D through Doppler measurements. However, the present technique need not be limited to such an embodiment. For example, light distance measuring techniques can also be employed. In such a case, the functions of generators 22 and 28 can be merged with the light passing through waveguide 24 also being utilized to measure the distance D.
Finally, the distal end of the apparatus 10 is connected to a photo detector and distance signal detector 30 which detects and measures the desired wavelengths and signals reflected back from the tympanic membrane 12. Preferably, detector 30 will include means for detecting the temperature of volume 19. As previously described, tympanic temperature measurement is well known.
A circuit 32 (shown schematically in FIG. 1) is provided for calculating the level of the constituent in the blood in response to a reduction in intensity of the testing light between the light generator 22 and the detector 30. The circuitry, through algorithms which will be described, compares the reduction in intensity with a reduction in intensity of the non-absorbable wavelength and with the measured distance D. In response to the measured variables, the circuit 32 calculates the glucose level in the blood in the tympanic membrane 12.
The circuit 32 includes a crystal oscillator 34 for driving the circuitry 32. Timing control circuitry 36 is provided for synchronizing the light generation and detection of the apparatus 10. A multiplexer 38 is provided for multiplexing the signals and light pulses to be generated by generators 22 and 28.
A signal preamplifier and demultiplexer 40 is provided for receiving the detected signals from detector 30 and amplifying and demultiplexing into individual signals representing the intensity of the reflected absorbable and non-absorbable wavelengths, the temperature of volume 19 and a signal to be used in calculating distance D. In the preferred embodiment, at least two light wavelengths (a wavelength absorbable by glucose and a reference wavelength not absorbable by glucose) are anticipated. However, in FIG. 1, up to N wavelengths are disclosed representing the utility of the apparatus for testing for multiple blood constituents and having multiple reference wavelengths. The first wavelength signal (for example, the testing light wavelength absorbable by glucose) is admitted to a first decoder 42. Other signal wavelengths (such as the reference wavelength not absorbable by glucose) is admitted to additional decoders such as decoder 44 (labeled decoder N in FIG. 1). A decoder 46 is also provided for decoding a signal representing the detection of the signal from the distance signal generator 28. The decoders place the demultiplexed signals in proper sequence.
All decoded signals are passed through filters 48-50 (for noise filtration) and subsequently through amplifiers 53-55. The amplified signals are passed through an analog-digital converter 56 to a microprocessor 58. Within the microprocessor 58, the signals are analyzed for the purposes of calculating the distance D and comparing the reduction in intensities between the absorbable wavelength and the non-absorbable wavelength for the purposes of determining the concentration of glucose within the blood in the tympanic membrane. A display 60 is provided for displaying to a healthcare provider the measured unknown (i.e., the blood glucose concentration).
It will be appreciated that circuitry for generating multiplexed infrared light and near-infrared light is well known. It will also be appreciated that circuitry and apparatus for measuring distances (such as distance D) through either ultrasonic or light measurements (including Doppler measurements) are well known. Also, it will be appreciated that apparatus and circuitry for detecting reflected light and demultiplexing signals are well known. Further, it will be appreciated that algorithms for calculating blood constituent levels in response to measured reductions in infrared light intensities are well known (see, e.g., U.S. Pat. No. 4,427,889).
The foregoing description identifies structure and apparatus and a method of testing which eliminates certain of the disadvantages of the prior art. For example, multiple constituents may be tested through non-invasive testing by multiplexing a plurality of wavelengths which are selectively absorbable by the blood constituents to be measured. Alterative to multiplexing, the light can be evaluated through software algorithms.
The present technique also utilizes a temperature control circuit 62 for controlling the intensity of an infrared heater wavelength generated by generator 22. The temperature control circuitry 62 receives a signal from preamplifier 40 representing the temperature of volume 19 and tympanic membrane 12. In response to the signal, circuitry 62 controls generator 22 to heat and control the temperature of the tympanic membrane 12 and the auditory canal 18 to a sufficient elevated temperature to ensure that blood vessels within the tympanic membrane 12 remain open and that the measured absorption does not shift due to temperature change. As a result, the present apparatus and method have enhanced reliability over the prior art.
Importantly, the non-FTIR technique measures the exact distance D that light is traveling from its source to the sample and back to a detection apparatus. It will be recognized that in spectrophotometric methods, the control of a distance of the light path (to eliminate variability in the signal measurement) is essential since the reduction in intensity of the absorbable wavelength is a function of the distance it is traveling as well as the concentration of the constituent to be measured. Prior art apparatus for measuring blood glucose and other body constituents were not capable of measuring the actual light path distance which could vary from test to test. Instead, prior art apparatus had a fixed light path distance (see, for example, U.S. Pat. No. 4,014,321) or required the measurement of a so called "apparent" light path distance (see, for example, U.S. Pat. No. 4,805,623).
The foregoing description disclosed two principle aspects of the non-FTIR technique: (1) a comparison of reduction in intensity between an absorbable and a non-absorbable wavelength and (2) the determination of the precise light path distance traveled by the absorbable and non-absorbable wavelengths. The utilization of these elements in combination with temperature control of the test area result in a blood constituent measurement device which is particularly suitable for non-invasive testing.
In the preferred example, the apparatus is carried on the distal end of a device to be inserted within the auditory canal of an ear. This will provide a simple, quick and accurate testing of blood glucose in a patient. However, certain of the salient features of the present invention (such as, the measurement of the precise distance and comparing reduction in intensity between non-absorbable and absorbable wavelengths) is also suitable for use in in vivo testing.
A particular structure for an in vivo application is shown in FIG. 2. In FIG. 2, a preferred apparatus 80 is shown inserted within a blood vessel 82. The apparatus 80, while shown in blood vessel 82, can be placed in any body cavity (e.g., the peritoneal cavity).
The apparatus 80 includes a generally cylindrical membrane 84. Preferably, membrane 84 is selected to be permeable to the blood constituent to be measured. In the case of measuring blood glucose, membrane 84 is preferably dialysis tubing having a molecular weight cutoff slightly greater than the molecular weight of glucose (i.e. greater than 180.16). To illustrate the permeability of membrane 84, holes 86 (shown greatly exaggerated in size) are provided passing through the membrane 84.
First and second waveguides 88 and 90 (preferably optical fibers) are provided inserted into opposite ends of membrane 84. The fibers can be press, fit and sealed in membrane 84. First waveguide 88 has a concave end 89 opposing a convex end 91 of second waveguide 90 Concave end 89 directs light toward end 91.
As in the previously described embodiment, multiplexed light wavelengths can be passed through waveguide 88 toward waveguide 90. The multiplexed wavelengths will include a wavelength absorbable by glucose and a non-absorbable wavelength. The absorbable and non-absorbable wavelengths pass through the membrane 84 between waveguides 88 and 90 and are passed from waveguide 90 to the circuitry (not shown) such as that shown and described in the aforementioned embodiment. When passing through the membrane 84, the intensities of both the absorbable and non-absorbable wavelengths will be reduced. The absorbable wavelength will be particularly reduced in response to the concentration of glucose within the membrane 84. By comparing the reduction in intensities between the absorbable and non-absorbable wavelength, the concentration of glucose within the membrane (and hence in the blood) can be determined if the distance D' between ends 89, 91 is known.
To measure distance D', an additional wavelength can be multiplexed with the absorbable and non-absorbable wavelength. The additional wavelength is selected to be passed from waveguide 88 toward waveguide 90 and reflected back from waveguide 90 as back reflection into waveguide 88. Through Doppler measurement techniques, the reflected light can be utilized to measure the accurate distance D, between waveguides 88 and 90. It will be appreciated that the phenomena of back reflection forms no part of this invention per se and can be accomplished through selecting particular wavelengths to reflect off of waveguide 90 or through the additional use of partially reflective coatings on surface 91. As a result of Doppler measuring the distance D' between waveguides 88 and 90, the present technique can compensate for distance variations between waveguides 88 and 90 which may result from compression due to posture of the patient, thermal expansion, manufacturing tolerances and other causes.
The use of the in vivo apparatus 80 is particularly suitable for constantly monitoring the blood constituent level of a patient. Continuous monitoring is desireable during surgical procedures. Also, continuous monitoring permits feedback control of chemical administration to patients. For example, with reference to FIG. 3, it is schematically shown how the present technique can be utilized to control the administration of insulin to a patient. In FIG. 3, an insulin source 100 is shown connected via a delivery pump 102 to a patient 104. The apparatus of the present technique 106 (which includes the apparatus 80 plus the circuitry of FIG. 1 or just the entire apparatus 10 of FIG. 1) is shown connected to the patient 104 to constantly monitor the blood glucose of the patient. The measured blood glucose level of the patient as monitored by the present invention 106 is utilized to control the action of the delivery pump 102 in order to maintain the patient's blood glucose within predetermined tolerances of a desired blood glucose level.
The foregoing discussion pertains to use of spectrometry in a non-FTIR application (i.e., an application utilizing other than techniques known in Fourier transform infrared spectrometry). However, the concepts disclosed in the prior discussion (namely the use of the ear drum or tympanic membrane as a target for spectral analysis of blood constituents) may be applicable to use in an FTIR application.
FIG. 4 is a schematic representation of an FTIR spectrometry apparatus for use in testing blood constituents. The apparatus, as will be more fully described, utilizes a body tissue as a target and as a moving reflecting mirror in the FTIR process. In a preferred embodiment, this concept is disclosed using the ear drum as the tissue which is the moving mirror in the FTIR process. In a preferred embodiment, the apparatus is shown for use in an non-invasive embodiment. However, it will be appreciated by those skilled in the art that the concept of utilizing a body tissue as the moving mirror in an FTIR process need not be limited to a tympanic membrane in a non-invasive embodiment, but may also utilize other body tissue as the moving target, whether invasive or non-invasive.
Referring now to FIG. 4, an FTIR apparatus is shown in a schematic format. The apparatus is contained within a housing 200 which is sized to be snugly received in the auditory canal 202 of the human ear and opposing tympanic membrane 204. The ear drum 204, auditory canal 202 and housing 200 seal off a portion of the auditory canal 202 to define a test chamber 206. In this respect, the housing 200 is similar to the apparatus 16 as shown in the embodiment in FIG. 1. Contained within the apparatus 200 is a source (such as a tube) 208 for admitting or removing a flow 210 of air into or from the chamber 206 to move or modulate the tympanic membrane 204.
A light source 212 is provided for generating a beam 214 of light which includes wavelengths absorbable by the constituents of interest (for example glucose) contained within the tympanic membrane 204. Preferably, light beam 214 is a broad spectral beam to allow absorption analysis at different wavelengths as will be described.
The apparatus also includes a beam splitter 216 for splitting the light beam 214 into a reference beam 218 and a test beam 220. The test beam 220 is directed toward the tympanic membrane 204. The reference beam 218 is reflected off of a fixed position mirror 222 toward a light detector 224. The housing 200 also contains distance measurer 226 and an infrared heater 228 which serve the function and purpose as the distant signal generator 28 and infrared heater 22 (together with warming temperature control 62) of the embodiment of FIG. 1.
In both the FTIR and non-FTIR embodiments described in this application, an infrared heater (heater 228 in FIG. 4 and the heater coupled with source 22 in FIG. 1) is used to control the temperature during measurement. While a separate infrared heater is shown in the preferred embodiment, the use of a separate heater may be avoidable by controlling the energy or load of the infrared light sources. Namely, the energy from the infrared light sources may be sufficient to warm the ear area. By simply measuring or monitoring the temperature, the duty cycle of the light sources may be varied to control the temperature. In such case, a separate infrared heater would be unnecessary.
With the apparatus as shown and described, light which is reflected off the tympanic membrane 204 results in a modified beam 230 of light where certain of the wavelengths of the test beam 220 have been absorbed by the constituents within the tympanic membrane 204. The amount of absorption and the wavelengths at which the absorption occurs is indicative of the types and amounts of constituents present in the blood within the tympanic membrane 204. The modified light 230 is received at the detector 224 together with the reference beam 218 reflected off of mirror 222. The modified beam 230 and the reference beam 218 interact to form an interference pattern which is measured and detected by detector 224 to generate a signal which is received and processed by a main processor 240. The processor determines the constituent level in response to the interference pattern. It will be appreciated the processes for performing such an analysis form no part of this invention per se and are known in the art. For example, the aforementioned article of Arnold and Small describes a procedure for using FTIR technology to determine glucose levels in a sample.
With the present apparatus as shown in FIG. 4, the tympanic membrane can be utilized as the moving mirror by injecting or removing air through air source 208 to increase or decrease air pressure within chamber 206. This will result in movement of the tympanic membrane 204. Hence, the tympanic membrane 204, while moving and reflecting beam 230 back to detector 224, becomes the moving mirror in an FTIR system.
The present apparatus has numerous advantages in that it is full-spectrum permitting a test for interference wavelengths over many wave bands. As a result, many constituents can be simultaneously tested and different points of absorption for a particular wave constituent spectra can be tested.
It is recognized in FTIR systems it is necessary to control and know the distance from the light source to the mirror as well as controlling temperature. To effect these controls, the infrared heater 228 is provided and distance measure 226 is provided, the structure and function of which having been previously described with reference to the previous embodiments of FIG. 1.
By gradually increasing and/or decreasing air pressure within the auditory canal, the tympanic membrane moves and becomes one axis of the interferogram generator system in the FTIR spectrometer. The other axis of the interferometer system is provided by the split beam reflected off of the stationary mirror 222. The full system permits the generation of a signal averaged, high resolution full-spectral scan. This permits the detection and quantification of many compounds of biological interest through both non-invasive and invasive testing as well as continuous testing to provide a continuous signal indicating changes in constituent levels. The latter would be particularly useful to monitor constituents during procedures such as surgery.
FIG. 5 shows modified use of FTIR technology with invasive testing. The reader will recognize the embodiment of FIG. 5 being similar to that of FIG. 2. Accordingly, similarly numbered elements are numbered identically in FIG. 5 except for the addition of the extra prime ('). As shown in FIG. 5, the apparatus 80, includes a generally cylindrical membrane for defining a cylindrical chamber 84'. The chamber 84, is preferably selected to be permeable to the blood constituents to be measured. In the case of measuring blood glucose, the chamber 84' is preferably a dialysis tubing with a molecular weight cutoff slightly greater than the molecular weight of glucose. To illustrate the permeability of the chamber 84', the whole of 86' (shown greatly exaggerated in size) is provided passing through the membrane of chamber 84'. In a preferred embodiment, the apparatus 80' is shown inserted within a blood vessel 82'. It will be appreciated that the apparatus 80' could be placed in any body cavity.
A first waveguide (preferably an optical fiber) 88' is inserted within one end of the chamber 84' and terminates at preferably a flat end 89'. End 89' opposes a membrane 91' (at least partially reflective) disposed at an opposite end of chamber 84'. The flat axial membrane 91' is movable relative to the end 89'. For example, the membrane 91' may be vibrated through ultrasonic application. Also, membrane 91' could be a piezoelectric film and a charge across the membrane 91' could be varied to move the film 91'. Alternatively, the apparatus 80' could simply be placed against an artery with the membrane 91' flexing and moving in response to blood pulsing through the artery. With this structure, the membrane 91' becomes the moving mirror in an FTIR application. The distance D" can be measured in a manner similar to the measurement of distance D' in the embodiment of FIG. 2. The membrane 91' reflects light back through waveguide 88' to produce an interferogram with a previously split off reference beam.
In several embodiments discussed in this application, the tympanic membrane was used as a target or a moving mirror. The use of the tympanic membrane as a target or as a moving mirror in testing for blood constituents has many advantages. The tympanic membrane is very thin, which aids in calculating or knowing the path length traveled by the light source. Also, the tympanic membrane contains both tissue fluid and whole blood. This makes for a better sample. The tympanic membrane is highly vascular and receives a constant blood flow even when a patient is injured or sick. There is little bone or fat within the tympanic membrane thereby providing a simple matrix. Also, the membrane is generally planar and reflective, which aids in spectrometric analysis. The membrane is accessible and temperature controllable. Also, the ear canal can be readily closed to provide an enclosed test area. Finally, the membrane is movable to permit its use as a moving mirror in an FTIR application.
Through the foregoing detailed description of the present invention, it has been shown how the objects of the present invention have attained in a preferred manner. However, modifications and equivalents of the disclosed concepts, such as those which would readily occur to one skilled in the art, are intended to be included within the scope of the claims of the present invention.
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|U.S. Classification
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|International Classification
|Cooperative Classification
|European Classification
|Dec 4, 1990
Owner name: INOMET, INC., 2660 PATTON ROAD, ROSEVILLE, MN. 551
Free format text: ASSIGNMENT OF ASSIGNORS INTEREST.;ASSIGNORS:KNUDSON, MARK B.;SHAPLAND, JAMES E.;REEL/FRAME:005528/0517
Effective date: 19901204
|Jun 30, 1995
|Fee payment
Year of fee payment: 4
|May 10, 1996
Owner name: INTEG INCORPORATED, MINNESOTA
Free format text: CHANGE OF NAME;ASSIGNOR:INOMET, INC.;REEL/FRAME:007927/0763
Effective date: 19950710
|Aug 3, 1999
|Maintenance fee reminder mailed
|Jan 9, 2000
|Lapse for failure to pay maintenance fees
|Mar 21, 2000
|Expired due to failure to pay maintenance fee
Effective date: 20000107


text:
Truck World, held every two years, is the largest trade show in Canada for all those involved in the economically vital transportation industry.
Exhibitors will feature the latest in trucks, trailers, heavy duty parts and accessories, engines and power train components, service shop equipment and supplies, tires, fuels, financial services, and many other products and services used in the trucking industry. Truck World is where the decision makers in the Canadian trucking industry come to see and buy. Attending Truck World are transport company owners, fleet managers and drivers, owner / operators, managers and purchasing agents, service shop owners, private carriers, garage personnel, government transport officials and heavy duty parts jobbers.
CFMS, taking place on April 13, 2016 will be held in conjunction with Truck World which runs April 14 – 16, 2016 at the International Centre, Toronto. Your registration to CFMS will include a free pass to Truck World including a ticket to the Kick-Off Breakfast. For more information about Truck World please visit www.truckworld.ca


text:
Laser for Butt Lifting - Lasers with a Brazilian Butt Lift
I an really interested in the Brazillian Butt lift butt don't want to have actual lipoSUCTION. Can the transfer be done after one of the less... READ MORE
Is There a Difference Between the Brazilian Butt Lift and Miami Thong Lift?
Recently heard about the Miami Thong Lift...sounds similar to a BBL but the scar is perfectly placed to hide under a thong. I can't find a ton of... READ MORE
Can I Schedule These Surgeries a Month Apart?
I want to get as much surgery done this summer. I'd like to combine a breast lift with an arm lift and have a second procedure Brazilian butt lift... READ MORE
Brazilian Butt Lift Alternative for a Butt That is Too Saggy
What other procedures might work to enhance a saggy butt? READ MORE
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Compare fat grafting techniques for the Brazilian Butt Lift. What technique is having great results? READ MORE
How do I Ensure Good Post-Op Results if I Combine Brazilian Buttlift and Breast Implants?
5'1, 175 lbs. Breast are 36 dd, will have then lifted and implants inserted. Interested in liposuction with a brazilian butt lift. READ MORE
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I had a regular butt lift years ago and am extremely unhappy with the results! My butt is flat and has a very unsightly indentation where the scars... READ MORE
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But I had 5 children I dint have the same shape I had before I just want my butt a little bigger and lifted up. Want to know can I get a butt... READ MORE
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Dr Duran (BBL and Breast Lift)
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I don't like my saggy butt. I would like to get a lift but without the fat transfer just to get a round nice shape. I have a lot of fat on my butt,... READ MORE
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Also panniculetomy or full TT? After massive weight loss ~80 lbs, I am very unhappy with my stomach and my butt especially but since I want kids... READ MORE
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I also plan on getting my breast lifted. But since i will be paying all cash at the moment I wont be able to do both procedures. I understand that in... READ MORE
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I am looking into getting a Brazilian butt lift but I am also looking for an estimate of how much it cost? (photos)
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text:
The King of Fighters Online is a Korean produced MMORPG for the The King of Fighters series. It is developed by Dragonfly -who also made Metal Slug Online Zero- and Triple A Games. Beta testing is slated to begin in 2010. The game is advertised to appeal to MMO fans as well as fans as the original series and will be in full 3D.
So far, what's been leaked is that the game will be a quasi-RPG beat'em up. Players can switch between characters from the games whilst they fight several original villains. They can perform many of the attacks that appear in the series and can level up as they progress. The action is in real time and quick to perform. The only time when the action freezes is to quickly see the entrance of the boss character on the map. Player vs Player options are also available. While so far the only stage seen is a factory, more are in the works and will be environments interactive to the actions of the player. Combos are also a work in progress.
- Kyo Kusanagi
- Athena Asamiya
- Terry Bogard
- Mai Shiranui
- Joe Higashi
- Kula Diamond
- Rugal Bernstein
- Omega Rugal
See AlsoEdit
External LinksEdit
- DragonFly official listing - in development heading
- Official trailer
- Dragonfly announcement
- Early screenshots


text:
This is where we start to see the silly temper tantrums and super effeminate behaviour of Dr. Smith. I use to love this episode but now when I watch it all I see is the beginnings of the shows changes to silliness and stupidity.
The basis of a drought and the family searching for water is great but the heavy plot stops there. Dr. Smith and Debbie eat some strange fruit and grow giant sized. Dr.Smith becomes a pain in the rump and plans revenge on the Robinson's for his change and Debbie is just well... a monkey with a bad hat.


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To make dance routines flashier, professionals often wear sequined outfits or burlap sacks filled with fireworks. Light up the dance floor with this Groupon.
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Beau Emerton
Toka Toka: Forbidden Fiji
Rarely is permission given to surf the forbidden breaks of the Fiji island chain, so when a select group of top international surfers gets the opportunity, it becomes a trip of legendary proportions. Discovering the surf treasures of hidden islands, these pros go at it knowing it's a once-in-a-lifetime experience. The adventure features Ian Wash, Andy Irons, Alex Gray, Bruce Irons, Keala Kennelly, Mick Fanning, Jamie O'Brien, Ben Dunn and more.


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GM Repair Problems? Ask GM Repair Expert Now.
O2 sensors on the drivers side are bank 1. O2 sensors on the passenger side are bank 2. Sensors ahead of the catalytic converter are #1 sensors and sensors behind the catalytic converter are #2. For instance, the 02 sensor Bank 1, sensor 2 is located on the drivers side behind the catalytic converter.
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American Fork:
Sharen L Larson
Park City:
Cindy Wilde
Kassie Cressall
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