text:
Abstergo Entertainment was a subsidiary of Abstergo Industries. The company was tasked to produce various multimedia consumer goods based on the technologies they'd developed.
Their strongest product was the Animus Omega, a gaming console version of the Animus. Their first game was called Liberation and was released in partnership with Ubisoft, a game developer and publisher company. The game followed the story of Aveline de Grandpré, and generated huge success for both companies.
Currently Abstergo Entertainment is focusing on the Identities Project, using the genetic memories they harvested from several Assassins throughout history, in the hope of finding new, interesting information for future projects.


text:
Police seek larceny suspect
Citizen Staff Reports 08/24/12
Henrico Police are seeking the public's assistance in locating Tyrell Eliphues Davis, who is wanted for eight charges including two felony charges of larceny. Davis is also a person of interest in several other larcenies in Henrico County.
Davis is a 22 year old black male, approximately 5'11" and 195 pounds with black hair and brown eyes. His last known address is in the 4100 block of North Avenue in Richmond.
Davis is wanted for: unlawful entry, vandalism, trespassing, two counts of larceny, two counts of assault and obstruction/preventing someone from calling the police. These charges were placed after separate incidents occurred in January and May, 2012 in the 3900 block of Elberon Court and the 100 block of Engleside Drive.
Anyone with information regarding the whereabouts of Tyrell Eliphues Davis is asked to contact Henrico Police at (804) 501-5000 or Crime Stoppers at (804) 780-1000. Citizens can also text Crime Stoppers at 274637, using the key word "ITip" followed by your tip. Both Crime Stoppers methods are anonymous.
Rock on!
By Patty Kruszewski, Citizen Managing Editor 07/21/2017 FeaturesGeneral News
The painted rocks craze is thriving in Henrico, as a walk around the grounds of local libraries and parks will demonstrate. This rock was spotted near Libbie Mill Library, and there's a slideshow of many more uniquely-painted stones on the RVA Rocks Facebook page (https://facebook.com/groups/RVARocks/).
Painting and hiding rocks is a family activity appropriate for all ages, and parents especially like the way it fosters creativity and gets kids outdoors. > Read more.
Goochland man arrested at RIC with gun
Citizen Staff Reports 07/20/2017 General NewsPublic Safety
A Goochland County man was arrested at Richmond International Airport July 19 after Transportation Security Administration officers found a loaded semi-automatic handgun in the traveler's carry-on bag.
A TSA officer detected the 9 mm caliber handgun inside the man's carry-on bag as it entered the security checkpoint X-ray machine. The handgun was loaded with 12 bullets. > Read more.
Kansas man struck, killed while crossing West Broad Street
Citizen Staff Reports 07/20/2017 General NewsPublic Safety
A 54-year-old Kansas man was struck and killed by a car while attempting to cross West Broad Street near Bethlehem Road in the Near West End at about 10:30 p.m., July 19.
Julius A. McBride of Overland Park, Kansas, was struck by a car traveling east on West Broad Street. > Read more.
Julius A. McBride of Overland Park, Kansas, was struck by a car traveling east on West Broad Street. > Read more.
Henrico Police warn citizens to 'Take it, Lock it or Lose it'
By Ashley Luck, Special to the Citizen 07/20/2017 General NewsPublic Safety
Eastern parts of Henrico County have witnessed a recent increase in larceny from automobiles, so Henrico Police officials are spreading the word to encourage citizens to lock their vehicles.
Police are handing out and posting fliers and putting message boards in neighborhoods to educate residents.
There usually is a rise of larceny from automobiles during Christmas, spring and summer break, said Henrico Police Officer James Bupp. > Read more.
Glover to be inducted posthumously into Babe Ruth Hall of Fame
Citizen Staff Reports 07/19/2017 FeaturesGeneral News
Late Brookland District Supervisor Dick Glover will be inducted into the Babe Ruth Southeast Region Hall of Fame during a ceremony Aug. 14 at RF&P Park at approximately 6:30 p.m., prior to a 14-and-under Babe Ruth World Series game. The Glen Allen Youth Athletic Association, which is hosting the World Series, made the announcement July 18. > Read more.
Glover to be inducted posthumously into Babe Ruth Hall of Fame
Rolls-Royce supplier lands in Henrico
New Walmart opens in Eastern Henrico
Unattended oily rags cause fire in commercial building near Richmond Raceway
Crime Stoppers' Crime of the Week: July 17-23, 2017
- More News
Print Edition
Jul. 20, 2017Current edition | Archive
Weekend Top 10
'Five Flights' opens July 20 at CAT Theatre
Henrico actress lands role in Christian TV series
All's fair in food and fun
Restaurant Watch
- More Entertainment
Obituary – Hoyle S. "Chick" Walters
Obituary – Janet Sue Vest
Obituary – Barbara Jean (Chilton) Crider
- More Obituaries
Glen Allen woman raising companion dog
Guided tour of Malvern Hill planned as part of 'History at Sunset' series
Anthem LemonAid registration now open
- More Community
Growing a grown-up: Part II
How to grow an adult
Make 'em take the pledge: no more snuff boxes!
- More Opinions
Code Lacrosse joins Richmond Strikers
5 Henrico student-athletes win scholarships at awards dinner
RIR to host playoff race in 2018
- More Sports
|July 2017
Place an Ad | More Classifieds
CalendarEast End Robotics will provide an energizing look into the world of robots from 10 a.m. to 2 p.m. at Varina Library. Learn how students put real-world math and science concepts to the test in order to make robots solve problems. Students will have the opportunity to build and program robots. This program is intended for middle and high school-age students. For information on East End Robotics, visit http://www.eastendrobotics.org. Full text

subset: commoncrawl


text:
C. William Brown, 1860, Union County
This is a long shot for me, but I will try.On a civil war page I found a C. William Brown.Not listed on muster roll, but Federal records list him as a private in Co. I, 10th Arkansas Calvary who was captured at Lebanon (or Galena) Missouri on 10-20-1864 and was confined at U.S. Military Prison Rock Island, Illinois where he died on 3/18/1865.He is buried in Grave 1901 at Rock Island prison.This C. William Brown filed for a Federal land patent in Union County in 1860.
I do not have access to an indexed record of the 1860 Census for Union County.I am looking for a Cornelius Brown (b. abt 1816)(whose father was William) who married Elizabeth Jane Spradling and possibly had children Nancy E. (b. 1852), Julia A. (b. 1855), and John (b. 1959).
If this individual sounds familiar to anyone looking for a Brown family I would like to share information.


text:
Pay-Per-Minute Viewing
You can now enjoy this movie on your iPhone®, iPad®, or compatible Smart TV & Android devices.
Purchase Options
Pay-Per-MinutePurchase Minutes
Streaming Rentals
Available MP4 sizes:SD 480p (1.87 GB)
DRM-free downloads offer content that is not limited by standard Digital Rights Management (DRM) access technologies. These technologies allow hardware manufacturers, publishers, copyright holders and individuals to limit the usage of digital content.
When you purchase DRM-free downloadable content, that content is available for you to download on any computer and save to a disk whenever you like. You can also download to multiple computers. There is no timeframe associated with your purchase and the content will not expire.
Running Time: 119 minutes
Released: 11/2005
Studio Name: West Coast Productions
Series: Bomb Ass White Booty
Categories: Big Dick Interracial Gonzo Black Dicks/White Chicks Big Butt
Description: Warning! These asses are for real!
5 Scenes from Bomb Ass White Booty 4
Watch with a Subscription to the West Coast Productions Channel, with Pay-Per-Minute or Streaming Rental
Bomb Ass White Booty 4: Scene 1 Free Preview
Starring: Mia Bangg Rico Strong ... More Details
Stars: Mia Bangg, Rico Strong
Sex Acts: Oral Sex, Anal Sex, Vaginal Sex, Ass To Mouth, Deep Throating, Masturbation
Positions: Standing, Cowgirl, Reverse Cowgirl, Standing Doggy Style, Missionary, Standing Side Saddle, Side Saddle, Sitting
Settings: Living Room, Stairs, Kitchen
Bomb Ass White Booty 4: Scene 2 Free Preview
Starring: Caroline Pierce Jack Napier ... More Details
Stars: Caroline Pierce, Jack Napier
Sex Acts: Vaginal Sex, Oral Sex, Creampie, Deep Throating
Positions: Reverse Cowgirl, Side Saddle, Standing Doggy Style, Standing, Standing Side Saddle, Standing Missionary
Settings: Living Room
Bomb Ass White Booty 4: Scene 3 Free Preview
Starring: Rico Strong Naomi St. Claire ... More Details
Stars: Rico Strong, Naomi St. Claire
Sex Acts: Vaginal Sex, Oral Sex, Deep Throating
Positions: Kneeling, Cowgirl, Standing Doggy Style, Standing Side Saddle, Standing Missionary, Doggy Style
Bomb Ass White Booty 4: Scene 4 Free Preview
Starring: Summer Lynn Rico Strong ... More Details
Stars: Summer Lynn, Rico Strong
Sex Acts: Vaginal Sex, Oral Sex, Ass To Mouth, Anal Sex, Breast Play, Deep Throating, Masturbation
Positions: Cowgirl, Kneeling, Sitting, Standing Doggy Style, Standing Side Saddle, Laying
Settings: Living Room, Stairs
Bomb Ass White Booty 4: Scene 5 Free Preview
Starring: Georgia Peach Prince Yahshua ... More Details
Stars: Georgia Peach, Prince Yahshua
Sex Acts: Vaginal Sex, Oral Sex, Creampie
Positions: Doggy Style, Cowgirl, Reverse Cowgirl, Sitting, Side Saddle, Missionary, Standing, Standing Doggy Style, Standing Missionary, Spoons position
Recommended Movies
AEBN Cams


text:
These Millennium Falcon And Death Star cutting boards are made from wood, so they won't dull your knives.
Plus, you can join forces with both the Rebels and the Empire against the real scourge of the galaxy: vegetables.
Check out the Death Star version after the break…
Product Pages: Millennium Falcon / Death Star ($29.99)


text:
Serra Dona Francisca rankings
Difficulty ranking world: 4323 (all)
Ranking Brazil: 34 (all)
Difficulty score: 58.52 what?
Serra Dona Francisca ratings
(rate it)
Starting from Joinville,
the Serra Dona Francisca ascent is 30.38 km long. Over this distance, you climb 830 heightmeters.
The average percentage thus is 2.7 %.
Look for other sides to climb the Serra Dona Francisca.
Click here to open big profile.
Click here to open detailed route.
No stories submitted yet. Did you climb this mountain?
Did you climb the Serra Dona Francisca? Please send your cycling story, description or comments. You can also send us video's or send us pictures on the Serra Dona Francisca.
© climbbybike™ All rights reserved 2005 -


text: NEW YORK ( TheStreet) -- Internet domain registration company GoDaddy.com is reportedly putting itself up for auction. The company could sell for more than $1 billion, according to a Wall Street Journal report, which cites people familiar with the matter as saying Qatalyst Partners, a boutique investment banking firm run by Frank Quattrone, has been hired to handle the auction process. The report speculates that private equity could get into the bidding, noting that Vector Capital, a San Francisco-based buyout firm, completed its sale of Register.com to Web.com ( WWWW) for $135 million earlier this summer. On its Web site, GoDaddy.com says it's "largest domain registrar in the world in terms of total names under management" with more than 43 million names. The parent entity is called The Go Daddy Group Inc., and in addition to the namesake flagship company, it also operates Wild West Domains, a reseller of domains, and a few other domain-related businesses. GoDaddy.com is headquartered in Scottsdale, Ariz., and was founded in 1997 by Bob Parsons, who started the company with funds made from the sale of a tax software company he founded to Intuit for $64 million in 1994. The company made a big splash with its Super Bowl ads, and counts race car driver Danica Patrick as a spokesperson. -- Written by Michael Baron in New York. >To contact the writer of this article, click here: Michael Baron. >To submit a news tip, send an email to: firstname.lastname@example.com


text:
Hancock County death: Wife says man threatened to kill officers
The Hancock County prosecutor has asked for more time before filing possible charges in the case of a Greenfield homicide.
A woman is accused of shooting and killing her husband last Friday. It happened on South County Road 800 East in Greenfield.
Police found 57-year-old Gary Roberts shot in the basement. His wife Elizabeth is being held as a person of interest.
"She did what she thought was right," said Captain Jeff Rasche with the Hancock County Sheriff's Department about Elizabeth Roberts.
In the eyes of the law, though, shooting her husband because he was threatening to kill police, could still get Roberts charged with murder.
"Oftentimes you hear the statement, 'Wish somebody would have done something.' In this case, that she did do something, you know, she pulled the trigger," said Rasche of Roberts' decision to shoot her husband in the chest.
According to court documents, Roberts went to police last week, telling them her husband had become irrational and dangerous especially when drinking alcohol or taking prescription medications.
Roberts also told authorities her husband was having suicidal thoughts and had a large number of guns and explosives in their Greenfield home.
According to a probable cause affidavit, Mrs. Roberts said when she told her husband authorities were coming, her threatened that everyone was going to die.
"We wouldn't have just gone up and knocked on the guy's door and said, 'Hey, we're here to get your guns and now you're going to go with us'," explained Rasche.
Police never got the chance, though. According to investigators, Elizabeth Roberts shot her husband once in the chest and called them to report it.
"Obviously, she saw something that Friday afternoon that caused her to take action that she had never seen before," said Rasche.
Now, the Hancock County prosecutor is faced with a tough decision, whether Elizabeth Roberts should be charged with murder or whether she had no choice and ultimately saved lives with her actions.
"If she is not charged here, is that going to give the next person out here in the community an idea, 'Well, my neighbor's crazy' or 'I think my neighbor's having some psychological issues or some mental issues.' Does that give him the right to go over there and shoot their neighbor?" asked Rasche.
The prosecutor's office could make a decision this week about the case.


text:
- About
- For researchers
- For organizations
- Contact us
- Log in or Sign up
Data from: Levers and linkages: Mechanical trade-offs in a power-amplified system
Date Published: March 10, 2014
DOI: http://dx.doi.org/10.5061/dryad.m8q8h
Content in the Dryad Digital Repository is offered "as is." By downloading files, you agree to the Dryad Terms of Service. To the extent possible under law, the authors have waived all copyright and related or neighboring rights to this data.
|Stomatopod biomechanical data
|49 times
|Using 196 specimens from 36 stomatopod species we measured 3 biomechanical metrics related to the raptorial strike. These include the minimum Kinematic Transmission (KT) during strikes, the Mechanical Advantage (MA) of the propodus lever system and the Reach of the appendage defined as the distance that the distal two segments of the appendage (propodus and dactyl oriented at 90° to each other) extend beyond the body during prey capture/acquisition. In addition, we measured the length of the carapace to act as a proxy for body size. The Reach measure was divided by this size measure to create a 'size-corrected' Reach metric to use in figures.
|Andersonetal2014_data.xlsx (58.95 Kb)
|View File Details
When using this data, please cite the original publication:
Additionally, please cite the Dryad data package:
We encourage organizations to:


text:
The Question of God: C.S. Lewis and Sigmund Freud with Dr. Armand Nicholi
Harvard professor Dr. Armand Nicholi turns your living room into a classroom, where he juxtaposes atheist Sigmund Freud's criticisms of religion against the staunch beliefs of celebrated author and Christian C.S. Lewis. Through dramatic storytelling, visual re-creations and insights from top historians and biographers, Nicholi presents a lively discussion embodying opposing views in the debate over whether God actually exists.
Rent DVDs for only $4.99 a month.
Movie Details
- Format
- Ratings
NRNot rated. This movie has not been rated by the MPAA.
Full Screen 1.33:1Subtitles
NoClosed captioned
NoLanguage and sound
English: Dolby Digital 2.0 StereoOther features
Color; interactive menus; scene access.
The Question of God: C.S. Lewis and Sigmund Freud with Dr. Armand NicholiClose
For Parents
Common Sense Note
- Age appropriate
- Not an issue
- Depends on your kid and your family
- Not appropriate for kids of the age most likely to want to see it


text:
483' of Lake Michigan Shore! Gorgeous 1.0 ac building site offering panoramic views of Lake Michigan. Available to purchase w/adjacent home to the North for a total of 22+ acres & 972' of shoreline. The 10 ac parcel can be divided & may be eligible for a forest program. Excellent hunting w/frequent visits from deer & turkeys. Close to highway for an easy commute.
Features Land
|Lot Size:
|Approx Acres: 10.1
|School District: Kewaunee
|High School:
|Middle School:
|Elementary School:
|Taxes: $1,040
|Tax Year: 2016
|Body of Water: Lake Michigan
|Lot Description:


text:
Fifa World Cup Panini Mexico World Cup 1986 Album. Mexico86, Pique.
- Sold for: Start Free Trial or Sign In to see what it's worth.
- Item Category: Sports
- Source: eBay
- Sold Date: Jun 20, 2014
- Channel: Auction House
This MEXICO86 Panini Album is in good condition for it's age (28 years old)Missing some stickers check pictures , the middle page came loose, if you have questions please ask before bidding. Thanks for looking.


text:
Tags: AirBnB, app, Apple, apps, iOS 7, mobile, Phone, Smartphone, smartphones, tablet, Tablets, update.
Posted 11/13/2013 at 4:27 PM
Posted 4 years ago
Version 3.0 of AirBnB, the worldwide travelers' app, has been made much better through iOS 7. It has a different look and the asked-for hosting capabilities long awaited. As you scroll down in the listings you get to see how beautiful, large, and clear everything is now.
Managing inquiries and replying to guests via an all new Host Home section is also available. Getting involved in virtual or local AirBnB host communities is a wonderful new improvement, to go with everything else that iOS 7 has brought to the application .
You must be logged in to post a comment.


text:
With the improvement in the global economy many technology and life science companies are raising funds by listing on stock markets around the World. The webinar provides a practical overview of the IPO process for in-house and private practice patent attorneys who may be involved in preparing a company for listing.
The Chartered Institute of Patent Attorneys
95 Chancery Lane
London WC2A 1DT
020 7405 9450
020 7430 0471


text:
Visit Akio at Stratégie Clients exhibition 8-10 April 2014
Akio will attend Stratégie Client exhibition on 8 – 10 April 2014 in Paris, Porte de Versailles – Pavillon 7.1. Visit us at booth stand L24!
On agenda:
Conference " Inside stories of a successful customer experience"
On Tuesday, April 8 at 11:15 am - en salle 3 : led by Akio and April Santé Prévoyance.
Customer recognition, customizing your customer request… The customer interaction between the various channels (voice, e-mail, web, written) must be unified to offer the best of the customer experience. Discover the winning strategy of a unified approach implemented by a important actor in the insurance industry, April
|Malik FADEL,
Business Development and Marketing Director, Akio
|Laëtitia BERETTI,
Project coordinator, April
Santé Prévoyance
|Danielle BROYER,
Performance Director, April Santé Prévoyance
live demo « 100% happy »
Every day at 12:15 am, meet us on our booth for a live demo of our software , Akio™ Unified Interaction Center.
Enjoy some bubbles of champagne and discover our 2 new features: Akio Web Box – this guardian angel dedicated to your customer journey on the web and Akio Direct Voice which enables the management of outgoing calls campaigns.
NewsConferences Events News


text:
Zhen Ji by PamelaColnaghiWatch
©2011-2017 PamelaColnaghi
Zhen Ji from Dynasty Warriors 7
Lucca Comics 2011
Pic @ Sylvain Leobon
Lucca Comics 2011
Pic @ Sylvain Leobon
love the outfit and your amazing outy bellybutton! wow x
Fantastico! (^_^)b
Very cool~
soooooooooooo beautiful XD. I can't take my eyes of you in this photo
awesome details
Wow, that is fantastic!
wow, that is great!
OMG i love the costume
Senza parole, semplicemente stupenda!!!!!!!!!!
She makes a beautifull Zhen Ji. I really love details of her costume. <3
wow nice work on the costume^^


text:
The History of Japan The Asuka Period Emperor Kammu The Samurai The arrival of the Portuguese Hiroshima and Nagasaki The Onin War Heian Era (794-1185)
Shogun 1450 1500s 1945 Sources:
http://imgc.artprintimages.com/images/art-print/the-arrival-of-the-portuguese-in-japan-detail-of-loading-cargo-from-a-namban-byobu-screen_i-G-16-1637-GW5GD00Z.jpg 530-710 794
Present Remotely
Send the link below via email or IMCopy
Present to your audienceStart remote presentation
- Invited audience members will follow you as you navigate and present
- People invited to a presentation do not need a Prezi account
- This link expires 10 minutes after you close the presentation
- A maximum of 30 users can follow your presentation
- Learn more about this feature in our knowledge base article
Do you really want to delete this prezi?
Neither you, nor the coeditors you shared it with will be able to recover it again.
Make your likes visible on Facebook?
Connect your Facebook account to Prezi and let your likes appear on your timeline.
You can change this under Settings & Account at any time.
History of Japan
No description
Antonina Federrathon 27 January 2013
Comments (0)
Please log in to add your comment.


text:
Lärabar Bars
Lara Bars were first recommended to me by my nutritionist, who only recommends 100% organic. I am gluten-allergic, and all Lara Bars are gluten free. The lemon bars are really awesome, but my favorites are the Ginger Snap and the Coconut. Lara Bars are not made with high fructose anything, and nothing you can't pronounce. The ingredients are things like dates, figs, coconut, cocoa, ginger, cherries, bananas -- you get the picture. They are all chewy, sweet and satisfying!
color coded to cut down on cross contamination - Cool!Added 8 Years Ago from Uncommon Goods


text:
Simple Machine Projects for School?
In a Forces and Motion science unit, teachers will educate students on the types of simple machines. The concepts of simple machines build upon one another, which can make it much easier for a teac...
Read More »
Simple Machine Construction Ideas for School Projects?
Simple machines are essentially mechanical devices that function to change the direction of force, making work easier for the operator of the simple machine. Simple machines are the building blocks...
Read More »
Simple Machine Projects for the 4th Grade?
Simple machine projects for the fourth grade focus on machines that have little or no movable parts and use energy to complete a task. The six most common elementary simple machine learning activit...
Read More »
Simple Machine Science Projects?
Simple machines are all around us. From the playground, to the classroom, and almost everywhere we look. It is important to try to introduce simple machine projects into children' lives so they c...
Read More »
Simple & Compound Machine Projects?
Simple machines do work with one movement. There are six kinds of simple machines, the wheel and axle, screw, wedge, lever, inclined plane and the pulley. Compound machines are machines using more ...
Read More »


text:
A Danish informant said that the British spy agency MI6 allegedly refused to kill Al Qaeda leader Anwar al-Awlaki because it was against the law.
Morten Storm, a former biker who was hired by MIA to infiltrate Al Qaeda, converted to Islam and dabbled with radical Islamists before turning into a spy for Western governments.
Storm, 36, says that after telling MI6 of al-Awlaki's whereabouts they refused to kill him, stating that they were an intelligence agency that does not involve itself with killings abroad, said the Daily Mail.
UPI reported that Storm was told that al-Awlaki did not threaten British lives and therefore they could not kill him.
Storm was said to be key in tracking down al-Awlaki by introducing the Al Qaeda leader to his future wife.
The Danish national has fallen out of favor with the spy agencies for revealing the plot, said CNN.
The CIA has maintained that it was not the intelligence given to them by Storm that led to al-Awlaki's killing but instead was a "parallel operation."
Storm is angry that he was not credited for the killing.
He said he came forward because he feared a CIA reprisal after the events.
The US and Europe believed that al-Awlaki was a major player in the terrorrist organization, inspiring the so-called "underwear bomber" and the 7/7 bus attacks in London.
Awlaki, an American citizen, was killed in a CIA drone strike in September 2011.
Storm has a checkered background with numerous criminal charges and drug use.
He is said to have converted to Islam in prison to escape a life of crime, reported the Telegraph.
He had his change of heart in 2006 and became a double agent for the Danish secret service, PET.


text:
vertex move on the surface of the geometry
hi guys
i have a question,how can i move vertex just on the surface IN icem ? sometiomes,when i adjust the loacation of vertex to meet the geometry,i just think if i can just move vertex on the surface of geometry,i think it is very useful.
in icem ????
yes ,in icem i forgot it
in move verticies under the blocking tab, use fix x, y, or z. usually to move on the surface, you need to fix only one coordinate...
i use this feature in this video : http://www.youtube.com/watch?v=nuiRkZqaEz4
hope it can help
thanks ,i am chinese, whicn mean that i cannot see youtue. i know what you see ,but the surafce is three dimentional ( curved surface)
|All times are GMT -4. The time now is 18:51.


text:
Pantech has announced that it is about to release a new mobile phone based upon the Android operating system. Called the Vega X, the new phone is notable because it will feature a new class of adapted mobile memory called DDR2, usually found in PCs - but a first for any mobile phone (the company is no stranger to 'firsts', remember the 3D interface?) and one that will speed up the operations of the handset by a factor of 1.5, according to the Akihabaranews website
The Pantech Vice President, Lee Eung-joon, was so impressed with his company's new product, he could not help but be bullish in his priase for the Vega X, "When surfing the Internet, searching the Web running applications or 3D games, its speed is so fast that it could threaten the existence of personal computers."
The Vega X itself will run on Android 2.2 Froyo and will be powered by a 1GHz Snapdragon CPU. Arriving with a 4in screen of WVGA resolution, the phone will include a built in camera of 5-megapixels.


text:
How to Avoid XP Registration
Windows XP tries to register your copy of Windows at Microsoft's web site when installing XP. To avoid registering your copy of XP with Microsoft and force it into thinking you have completed the registration process, follow these steps:
1. Physically disconnect your modem
2. Turn on your computer
3. Start Windows XP Setup and answer 'No' when asked to use 'Windows Dynamic Update'
4. After the installation is complete, avoid setting up your internet connection when asked, instead click on 'Skip'
5. Click on the Start button and select Run. Type in 'regsrv32 -u regwizc.dll' and click OK then click OK again to close the confirmation dialog box which unregisters this dll file
6. Click on the Start button and select Run
7. Type in 'regedit' and click OK
8. Look for this string:
 HKEY_LOCAL_MACHINE\SOFTWARE\Microsoft\WindowsNT\CurrentVersion
9. Right-click on the 'RegDone' string and select 'Modify' then type 1 in the 'Value Data' box, then exit the Registry
10. Right-click on the 'Internet Explorer' Desktop icon and select 'Tools'. Click on 'Internet Properties' and change the default home page to anything except any Microsoft or MSN web site
11. Reboot your system
12. Right after XP reboots, but before Windows loads, be sure to reconnect your modem
My Angle
I understand for some certain reasons we do face the problem to activate Windows XP through internet. However, this tip is just only a temporary method to solve your conundrum. If you really can't activate XP via internet, make a phone activation isn't that difficult actually.
Subscribe to get free latest updates by email. Like our Facebook Page.
LIKE It & Leave A Comments
One Response to How to Avoid XP Registration
Please, can you PM me and tell me few more thinks about this, I am really fan of your blog…
Leave a Reply
You must be logged in to post a comment.


text:
Sleeveless Wrap Dress
Related Categories: Maxi Dress | Wrap Dress | Maxi | Womens Maxi Dresses | Black Maxi Dress | Wrap | Maxi Wrap Dress | Evening Dress
Turn the glamour dial up to 11 with this classic sleeveless maxi. Made from drapey viscose-elastane, this dress is clingy in a (very) good way: wrap detail skims you in at the waist, and you can adjust the fabric ties to give that hourglass shape even more definition.
- 95% viscose 5% elastane
- Machine washable
- Fitted shape
- Maxi length
- Drapey jersey with stretch
- Front lining in top
- Functional front tie
- Functional wrap
Sleeveless Wrap Maxi
£89.50 £71.60


text:
This pure evening primrose oil is cold-processed and void of any solvent residue, unlike other brands. Nu-Health assures quality, reliability, and purity.Here are just some of the possible health benefits of evening primrose oil:
Relieves the discomforts of PMS, menopause, menstruation, endometriosis and fibrocystic breasts
Eases the joint pain and swelling of rheumatoid arthritis
Prevents diabetes-associated nerve damage
Nourishes nails, scalp, and hair
Reduce the symptoms of eczema
Content: 200 softgels, 3 months supplySuggested Use: Take two softgels daily as a food supplement or as directed by your physician.Other Ingredients: Softgel capsule(gelatin, glycerin USP, purified water).
Made In U.S.A


text:
Need inspiration in the kitchen? Then sign up for a FREE daily e-newsletter from Food & Wine Magazine, with a delicious recipe idea in each edition! Plus get an instant download of Food & Wine Best New Chefs Recipes!
Food & Wine is the contemporary magazine for elegant dining and entertaining. Food & Wine is on a mission to find the most exciting places, new culinary experiences, emerging trends and sensations.
Check out HOT Amazon deals on your favorite items!


text:
In 2008, Alabama Chanin moved operations from a three-bedroom house at Lovelace Crossroads on the outskirts of Florence, Alabama, to a former textile manufacturing facility built in 1982 in the local industrial park. The Factory, as the space is now called, is home to Alabama Chanin's flagship store and a full-service café, along with the Alabama Chanin design and production studios and Building 14 Design + Manufacturing division. The Factory hosts an event space that is used by the community, with the ability to cater small lunches, host our Friends of the Café Dinner Series, lectures, and other exciting happenings. It also acts as our workshop headquarters.
Services from The Factory include custom orders and personal fittings, daily lunch and brunch, and event catering.
Visit here for hours, directions, events, catering services, and all of our offerings from The Factory.


text:
Extended through today!
Ring in the New Year with 101 FREE 4×4 or 4×6 Prints when you use code 101FREE at check out. Offer valid 1/1-1/4.
Get 101 Free 4×4 or 4×6 Prints! Use code 101FREE at check out. Valid 1/1-1/3 Offer is good for 101 free 4×6 or 4×4 prints through shutterfly.com, our mobile-friendly site or Shutterfly app. Promo can only be redeemed once per account and/or billing address. Taxes, shipping and handling will apply. Not valid on other print sizes, other products, prepaid plans, prior purchases and orders placed for in-store pick up. Cannot be redeemed for cash or combined with select offers or credits. Not valid for resale. We reserve the right to modify or replace any part of these terms and conditions without notice.


text:
Kevin Federline Cornrows
Maui, Hawaii :: Rapper extraordinaire Kevin Federline — perfectly coifed with cornrows and diamond studs — takes a puff from his cancer stick and strolls around Point Dume with his up and coming band (they are all going to be superstars after K-fed drops his album, you see). I have to agree with GQ when they said, "Kevin Federline is a spousal sex symbol of sorts, he's a new sort of trophy husband, and I think we'll be seeing more guys like him." Federline. Sex. Federline. Sex. I know you see it too. More pictures in the gallery!


text:
Best Of :: Bars & Clubs
Okay, so one of our favorite nightlife offerings starts before it gets dark, but the party often goes far into the night. Close enough. The DJ duo of Jared Alan and William Fucking Reed are two of the biggest party monsters Phoenix has to offer. Their respective Saturday night wingdings Cheap Thrills and Shake! have drawn in the hipsters and big-sunglasses crowd like stylish moths to a flame. So it seemed only natural when these two nightlife kings joined forces last year to create the popular summertime pool party series. Every Sunday afternoon from Memorial Day through Labor Day weekend, Alan and Reed spun scintillating mixes of indie rock, electro, and hip-hop for the swanky and tattooed masses at downtown Phoenix hotels. Organized by socialite maven Jen Deveroux, the swimming soirees (which were originally held at the Hotel San Carlos before moving to the Wyndham this year) became the place to be seen for hipster boys or funky, bikini-wearing femmes. Guests DJs also visited every week (ranging from local mixmasters like Benjamin Cutswell and Tricky T to such marquee-level names as Deee-Lite's Lady Miss Kier and UK breakbeat legend Adam Freeland) helping give the parties an extra aura of cool. Call us crazy, but Adult Swim makes us wish summer lasted all year long.
How is it that we've scraped this town, year after year, searching for drinking digs without ever coming across this little gem? The Ice House Tavern is really kind of a messed-up idea — but in a creepy, fantastic way. Anyone who grew up in Phoenix probably skated at Arcadia Ice Arena at least once in his or her life. Little did we know as fumbling, tumbling idiots on the rink that drunks were watching us the entire time. Yep, there's a bar connected to the rink where boozers can slurp their cocktails and peer through windows to the rink while wobbly skaters slide around on the ice. In 2009, local hipsters latched onto this hole in the wall and celebrated its slightly seedy — definitely cuckoo — novelty.
It's a bit of a haul for most Phoenicians — just over the Pinal County line south of Queen Creek — but a trip to San Tan Flat on a Saturday night is a real treat. Live music from a rollicking country band, a nice wide dance floor, and great food give this place an overall excellent atmosphere, but it's the wood-burning fire pits that really set the stage for a special night. Grab some wood off the pile and toss it on the coals, then buy some marshmallows from behind the bar. Before you know it, you'll be living the saloon's slogan: "All the fun of camping out, without having to sleep on the ground."
We love the Autostrada panini. And we love the smoked salmon bruschetta. And Postino Central's wine list is not only imaginative but always features several of our favorite libations. But what we really love most about this new-ish cafe (located in the old Katz's Deli building on North Central) is that seating on the patio lets us watch three entirely different slices of life, all at once. We can ogle the bar crowd that's hanging out just beyond the patio (where it's pretty easy to strike up a conversation with like-minded wine lovers at the next table), so our desire to watch drunk people hooking up is sated. Beyond that, the dining room is always filled with people having klatch-y catch-up meetings and clandestine conferences (last time we were there, we witnessed a mother-daughter donnybrook having to do with short skirts and withheld tuitions — scandalous!). And Postino's wide, single-pane picture window offers views of the street beyond the dining room. We can even see, from way back on the patio, the comings and goings at the Circle K across the street — which is a lot more interesting than you'd imagine. We're lurkers at heart, and we see a lot more than crusty bread and wine bottles when we hang at Postino Central.
We've always wondered: Where do bars and clubs go when they die (i.e., close)? Whisked away to the nightspot great beyond after falling to a wrecking ball, perhaps, never to return (like Tempe's Long Wong's)? Or maybe reincarnation into a completely new identity is in order, like when the old Mason Jar became gay dive Velocity 2303. In the case of The Sail Inn in Tempe, the legendary hippie hangout was revived, Lazarus-style, in its original location by owner Gina Lombardi. The original version of the Sail closed after it was bought out by real estate developers in late 2005, ultimately becoming the ill-conceived danceteria Trax, which fizzled out after 18 months. Fortunately, Lombardi swept in and resurrected her old stomping grounds earlier this year, upgrading the décor in the process. And though its look may have changed, Lombardi's continuing the old habit of booking a wide variety of musicians — ranging from the jam-rockers of Xtra Ticket and The Noodles to burgeoning indie acts like Black Carl — nearly every night since re-opening. It couldn't have happened at a better time, too, as The Sail Inn is just about the only dedicated music venue in downtown Tempe, an area once renowned for its live bands. Thanks, Gina.
Since debuting in January, Cream Stereo Lounge has endured a significant amount of both love and hate, much like any new nightspot. Its supporters easily gush about its mix of European and Las Vegas-style touches, including swimsuit-clad models engaging in burlesque-like bathtub shows. The haters, on the other side of the coin, have groused about alleged rude service, the club's minuscule size, and overpriced covers. But over the past few months, the grumblings have quieted down and the place is more popular than ever. One factor in its success has been the selection of superstar DJs that have been booked to spin here. The list is quite impressive, including Lee Burridge, Paul Oakenfold, George Acosta, and Paul van Dyk, just to name a few. Like the saying goes, the Cream rises to the top.


text:
Hotel Raviraj
Call us 1800-300-2400-1 (Toll Free) and Get additional Discount upto 50% for this Hotel.
You are getting lowest possible rate for this hotel
- About Hotel
- Reviews
About Hotel Raviraj
Hotel Raviraj is a budget accommodation in Pune that provides free Wi-Fi internet access and breakfast. It is located at 2 km from the Omkareshwar Mandir. It is reachable from the Pune Railway Station (5 km). This 1-storied hotel has 30 air-conditioned rooms. All the rooms have electronic safes, cable TVs, and STD/ISD direct-dial phones. Each room has an attached bathroom. The Pune hotel provides its guests with laundry, medical assistance, and room service. It houses a business center, banquet, restaurant, and cafe. Hotel Raviraj is located at 5 km from the Maharashtra State Road Transport Bus Depot and is accessible from the Pune Airport (15 km). A few places that guests can visit include the Chhatrapati Sambhaji Garden (1 km), Pune IT park (8 km), and Mahatma Phule Museum (2 km). This hotel operates a travel counter to assist its guests.
No of floors: 3 | No of rooms: 24
Checkin Time: 1200 pm
Checkout Time: 1200 pm


text:
Playing Cards For Designers Replace Suits With Color Codes [Pics]
Designed by Hundred Million, the cards feature the four ink colors with each one a variation of tone, from lighter to darker gradients.
Designed by UK studio Hundred Million, the CMYK Playing Cards feature the four ink colors used in printed media (cyan, magenta, yellow and black) instead of the suits found in a traditional deck. The numbers on each card were swapped for a percentage of ink on the surface, with a variation in tone from lighter to darker gradients. They write on their Kickstarter page:
The cards are just as useful as traditional printed styles, AND perhaps most importantly, all niche and only understood by people who are in our little design world. We've tried explaining the cards to people outside the industry and were met with almost perfect poker face expressions.
Hundred Million combined the opacities of ink with an anti-design rule, which means the only decoration is crop marks and registration bleeds usually unseen in the post-production world.
The playing cards are made from German black-core paper, with a linen finish, uniform back face design, and matte laminated card tuck box. The £3,000 Kickstarter goal has already been almost doubled and you can pre-order a pack of CMYK cards from the crowdfunding site for £9. Click through to see images of the cards:
Sources: Hundred Million, Kickstarter
Images: Hundred Million, Kickstarter


text:
Parameter adaptations during phenotype transitions in progressive diseases
The study of phenotype transitions is important to understand progressive diseases, e.g., diabetes mellitus, metabolic syndrome, and cardiovascular diseases. A challenge remains to explain phenotype transitions in terms of adaptations in molecular components and interactions in underlying biological systems.
Here, mathematical modeling is used to describe the different phenotypes by integrating experimental data on metabolic pools and fluxes. Subsequently, trajectories of parameter adaptations are identified that are essential for the phenotypical changes. These changes in parameters reflect progressive adaptations at the transcriptome and proteome level, which occur at larger timescales. The approach was employed to study the metabolic processes underlying liver X receptor induced hepatic steatosis. Model analysis predicts which molecular processes adapt in time after pharmacological activation of the liver X receptor. Our results show that hepatic triglyceride fluxes are increased and triglycerides are especially stored in cytosolic fractions, rather than in endoplasmic reticulum fractions. Furthermore, the model reveals several possible scenarios for adaptations in cholesterol metabolism. According to the analysis, the additional quantification of one cholesterol flux is sufficient to exclude many of these hypotheses.
We propose a generic computational approach to analyze biological systems evolving through various phenotypes and to predict which molecular processes are responsible for the transition. For the case of liver X receptor induced hepatic steatosis the novel approach yields information about the redistribution of fluxes and pools of triglycerides and cholesterols that was not directly apparent from the experimental data. Model analysis provides guidance which specific molecular processes to study in more detail to obtain further understanding of the underlying biological system.
Cardiovascular and metabolic diseases such as diabetes mellitus and metabolic syndrome are progressive in time
In systems biology mathematical modeling is applied to integrate different sources of experimental data of a phenotype and to investigate the complex interactions of underlying biological systems
In the present work, we propose a novel computational approach to analyze molecular adaptations in a biological system to overcome these problems. We use mathematical modeling to quantitatively integrate metabolic data of different phenotypes and subsequently exploit this mathematical framework to analyze which molecular processes have changed and are collectively responsible for the shift between phenotypes. This information is obtained by identifying the progression of necessary parameter changes required for the model to be consistent with the experimental data of these phenotypes. These changes in parameters reflect progressive adaptations at the transcriptome and proteome level, which occur at larger timescales than the metabolic processes. The approach involves consecutive steps of data gathering, model development, and parameter estimation, which will be discussed in detail. An advantage of our approach is that mathematical models containing processes at any timescale of interest can be used, while their long-term adaptations are captured by identifying necessary parameter changes. This enables us to study long-term aspects of short-term processes. Furthermore, in cases when the amount of information of the underlying biological system is limited, our approach could provide a means to describe adaptations in molecular processes without the necessity to develop detailed kinetic models of the modulating mechanisms. For instance, if one is interested in studying a metabolic pathway which is adapting due to activation of a signal transduction pathway, the modulating effects can be captured by identifying necessary changes in the metabolic pathway parameters rather than developing a mathematical model that includes an explicitly modeled signal transduction pathway. The approach, which is applicable to a multitude of biological systems, is demonstrated on the basis of a case involving the activation of the liver X receptor (LXR), a promising drug target for atherosclerotic therapies
The family of liver X receptors (LXR
Several theoretical sections are presented describing the methodology of the computational approach, which involves consecutive steps of data gathering, model development, and various parameter estimation steps.
Model development
The computational approach is developed to analyze progressively adapting biological systems that are modeled using a system of (non)linear ordinary differential equations (ODEs):
which is described by a set of functions
Simulating the biological system of phenotype A
Once a network topology of molecular species and corresponding flux descriptions are defined, values for the kinetic parameters
Identification of molecular adaptations from phenotype A to phenotype B
Parameter estimation to describe phenotype B
The mathematical model together with the collection of acceptable parameter sets, represents the biological system of phenotype A. Molecular processes that are responsible for the transition of the biological system from phenotype A to phenotype B, are determined by identifying kinetic parameters that necessarily have to change in order to describe the biological system of phenotype B. A first approach could be to repeat the large-scale parameter estimation protocol, employed on phenotype A, for phenotype B. However, apart from being computationally expensive, comparing parameter sets from different phenotypes with each other is problematic, as they are obtained independently from each other. For instance, in the case when multiple separate minima exist, it would not be possible to know which realization of phenotype A is the reference for a specific realization of phenotype B. However, the fact that phenotype B originates from phenotype A could be used to address latter problem. The acceptable parameter sets from phenotype A could be used as initial values and reoptimized by once more applying a weighted non-linear least squares algorithm, minimizing
Iterative data integration and parameter estimation
Parameter adaptations describing a phenotype transition are often not unique. For instance, in order to increase a specific molecular concentration, corresponding production and degradation parameters can be changed in infinitely many different ways to accomplish this. Here, we assume that adaptations are minimal and proceed progressively in time. Therefore, the concept described in the previous section was extended to study progressively adapting biological systems, by defining artificial intermediate phenotypes. Hereto, the experimental data is interpolated from phenotype A to phenotype B in a number of steps. For instance, for a linear interpolation scheme this would imply
Similar as in equation (3), for each parameter trajectory different realizations for
Regularization of parameter adaptation trajectories
It is assumed that adaptations are minimal and proceed progressively in time. Therefore, the parameter estimation protocol was extended to avoid needless change of parameters, hereby identifying minimal parameter adaptations that are necessary to describe a phenotype transition. To this end,
Consistency of parameter adaptation trajectories
The identification of parameter adaptation trajectories was performed for each acceptable parameter set, which gives information about the possible dispersion of parameter trajectories due to kinetic variations between the different acceptable parameter sets. However, given the uncertainties arising from experimental data and parameter estimates, the reliability of individual parameter trajectories is also a relevant topic to explore; is an observed trajectory consistent or is its path just a coincidental result? Given a certain parameter trajectory, it is important to analyze how reliable and consistent its path is to eventually draw conclusions about potential molecular adaptations that could have taken place. Therefore, the protocol described above was extended by not only determining parameter trajectories from phenotype A to phenotype B, but also backwards from phenotype B to phenotype A. A backward trajectory is obtained by interpolating the data from phenotype B to phenotype A, whilst reoptimizing the parameters. The final values of the model states and parameters obtained from the forward trajectory are used as initial values to calculate the backward trajectory. Furthermore, the reference parameter set
We presented a computational approach to analyze molecular adaptations in a biological system evolving through various phenotypes, which is generically applicable to different biological systems. In this section, the computational approach is demonstrated by applying it to a case of liver X receptor induced hepatic steatosis.
Experimental data
The acquisition of quantitative experimental data of different phenotypes is essential to gain insight in the progression of molecular adaptations in underlying biological systems. The available experimental data determines to a large extend the development of a mathematical model. The level of detail and precision at which certain biological processes can be integrated in a mathematical model, is determined by the selection of molecular species, as well as the type and quality of the measurements. With respect to the LXR case, several datasets of wild-type and T0901317 LXR activated C57BL/6J mice were obtained. Data was included containing measurements of hepatic triglyceride, free cholesterol, and cholesterylester levels, as well as plasma triglyceride, high-density-lipoprotein (HDL) cholesterol, total cholesterol, and free fatty acid levels in overnight-fasted mice
Additional file 1
Supplementary material. Description of model equations, additional analyses, implementation details, and experimental data.
Click here for file
Computational model of hepatic lipid and plasma lipoprotein metabolism
A mathematical multi-compartment model was constructed, based on the available experimental data, which integrates metabolic processes involved in hepatic lipid metabolism, as well as plasma lipoprotein metabolism (Figure
Figure 1
Hepatic lipid and plasma lipoprotein metabolism
Hepatic lipid and plasma lipoprotein metabolism. The mathematical model has three compartments representing the liver, blood plasma, and peripheral tissues. The liver compartment includes reactions representing the production, utilization and storage of triglycerides and cholesterols, and the mobilization of these metabolites to the endoplasmic reticulum, where they are incorporated into nascent produced VLDL particles. The VLDL particles are secreted in the plasma compartment where they serve as nutrients for peripheral tissues. Remnant particles are taken up and cleared by the liver. The model furthermore includes the hepatic uptake of free fatty acids and reverse cholesterol transport via HDL. ABCA1, ATP-binding cassette transporter 1; ACAT, acyl-CoA: cholesterol acyltransferase; ApoB, apolipoprotein B; CE, cholesterylester; DGAT, diglyceride acyltransferase; ER, endoplasmic reticulum; FFA, free fatty acid; FC, free cholesterol; HDL, high-density-lipoprotein; HSL, hormone-sensitive lipase; IDL, intermediate density lipoprotein; LDL, low density lipoprotein; LDLr, low density lipoprotein receptor; LPL, lipoprotein lipase; MTP, microsomal triglyceride transfer protein; SR-B1, scavenger receptor class B1; TG, triglyceride; TGH, triglyceride hydrolase; VLDL, very low density lipoprotein; VLDLr, very low density lipoprotein receptor.
Additional file 2
SBML file. Implementation of the mathematical model in SBML format.
Click here for file
Simulating the wild-type mouse
A large-scale parameter estimation protocol was employed to capture multiple parameter sets that describe the experimental data of phenotype A (wild-type C57BL/6J mice). Mass isotopomer distribution analyses indicate that the metabolic fluxes are expected to be in the
Figure 2
Parameter scatter plots and predictions
Parameter scatter plots and predictions. Several parameters are very constrained by the data and have a well defined value (A and B), whereas others show a larger spread of possible values (D and E). The black dots represent the 108 initial sampled parameter values (individual dots not visible), whereas the red dots represent the 104 best parameter sets which were optimized. The resulting 2909 acceptable parameter sets that describe the experimental data are shown in green. Model predictions for the depositioning of hepatic triglycerides (C) and cholesterylesters (F) in cytoplasmic and endoplasmic reticulum fractions were obtained for all acceptable parameter sets. Note that only the total pools of triglyceride and cholesterylester were measured. The predictions for the triglyceride fractions are consistent, whereas the predictions for the cholesterylester fractions show a larger spread of possible outcomes.
Parameter adaptations from the wild-type to the LXR activated phenotype
Using the previously described techniques, an analysis was carried out to study the metabolic consequences of T0901317 induced LXR activation. It was assumed that metabolic adaptations upon LXR activation proceed linearly in time
Figure 3
Single-step versus multi-step optimization
Single-step versus multi-step optimization. A) An example of an acceptable parameter set describing the wild-type phenotype, which was not successfully optimized by single-step optimization to describe the LXR activated phenotype. This problem was circumvented by multi-step optimization. In the latter case, the parameter estimation is carried out in a step-wise fashion. Hereto, the experimental data is interpolated from the wild-type phenotype to the LXR activated phenotype. At each interpolation step the parameters are reoptimized in order to describe the newly interpolated data. This procedure is repeated until the final state representing phenotype B is reached. B, C) Two examples of corresponding parameter trajectories from the wild-type phenotype to the LXR activated phenotype, normalized by the initial parameters of the wild-type phenotype.
The parameter trajectories were regularized according to equation (6) to avoid needless change of parameters. A potential risk of regularization, as always with multi-objective optimization, is that for a low
Figure 4
Effect of regularization strength
Effect of regularization strength. A) Model error
Figure 5
Regularization of parameter trajectories
Regularization of parameter trajectories. Three examples of parameter trajectories from the wild-type phenotype to the LXR activated phenotype obtained without regularization (blue dashed) and with regularization using
The uncertainty associated with parameter trajectories was investigated, among other things, by repeatedly calculating forward and backward trajectories. Figure
Figure 6
(In)consistency of parameter adaptation trajectories
(In)consistency of parameter adaptation trajectories. Three examples of back and forward parameter trajectories from the wild-type phenotype to the LXR activated phenotype, using a hundred repetitions.
The parameter adaptation trajectories were determined for all acceptable parameter sets and used to determine how the fluxes of triglycerides and cholesterols change in time from the wild-type phenotype to the LXR activated phenotype. The data interpolation was carried out in a hundred steps and the back and forward flux trajectories were determined using a hundred repetitions. Figure
Figure 7
Flux adaptations upon T0901317 induced LXR activation
Flux adaptations upon T0901317 induced LXR activation. Flux trajectories from the wild-type phenotype (green) to the LXR activated phenotype (red). The data interpolation was carried out in a hundred steps and the back and forward flux trajectories were determined using a hundred repetitions. Molecular fluxes (A-C, E-H) are given in mM/h, whereas the triglyceride concentrations presented in (D) are given in mM.
As described in previous sections, several parameters are not constrained by the data and show a large spread of possible outcomes. This makes the calculation of consistent quantitative trajectories impossible. Nonetheless, relative changes with respect to the initial values of the wild-type phenotype could still provide useful information, e.g., to determine ranges of feasible fold inductions of molecular concentrations and fluxes, and to discriminate between different possible scenarios. The latter could be used to generate new hypotheses and to guide the design of new experiments. An example is depicted in Figure
Figure 8
Adaptations in cholesterol metabolism upon T0901317 induced LXR activation
Adaptations in cholesterol metabolism upon T0901317 induced LXR activation. Adaptations in metabolic processes/components involved in hepatic cholesterol metabolism, normalized by the values of corresponding wild-type phenotype. The green dots represent the wild-type phenotype, whereas the blue and black dots represent the LXR activated phenotype. Solutions corresponding to an increased HDL-CE synthesis/uptake rate are colored blue, whereas solutions corresponding to a decreased HDL-CE synthesis/uptake rate are colored black. The ellipses were calculated by means of principal component analysis (PCA) and contain 95% of the corresponding solutions. ABCA1, ATP-binding cassette transporter 1; ABCG5, ATP-binding cassette transporter G5; SR-B1, scavenger receptor class B1.
To improve our understanding of progressive diseases such as diabetes mellitus and metabolic syndrome, the study of phenotype transitions is important. A challenging task is to explain the progression of phenotype transitions in terms of molecular adaptations in underlying biological systems. Here, we propose a novel computational approach to analyze biological systems evolving through various phenotypes and to predict which molecular processes are responsible for the transition. We presented a case involving the activation of the liver X receptor, a promising drug target for atherosclerotic therapies.
Parameter adaptation trajectories during phenotype transitions: strengths and limitations
A large-scale parameter estimation protocol was employed to capture multiple parameter sets describing the biological system of phenotype A. A collection of 2909 acceptable parameter sets were obtained that describe the experimental data. A substantial fraction of the optimized parameter sets were not acceptable. These parameter sets did either not describe the experimental data or displayed unphysiologically high fluxes for any of the reactions. It appeared that the latter criterion contributed significantly to the rejection of parameter sets. The efficiency of sampling acceptable parameter sets could potentially be improved by including the rejection criteria in the optimization objective function. Note, that the computational approach is not restricted to the parameter estimation protocol presented here. Various parameter optimization methods exist that minimize the difference between experimental data and corresponding model simulations, e.g., trust-region optimization methods, simulated annealing, and genetic algorithms
Parameter trajectories describing the phenotype transition were determined by interpolating the data between phenotypes. The data interpolation was carried out in a hundred steps. We have performed several tests by using different numbers of steps. Performing more than a hundred steps did not change the results significantly. The computational approach allows free choice of interpolation schemes. Hence, when information is available about the progressive nature of certain biological processes, this information could be incorporated in the interpolation scheme. Furthermore, the computational approach could be used to explore different possible transition scenarios by employing a variety of different interpolation schemes. The latter could be useful when sufficient information about the transition characteristics is lacking, e.g., to test hypotheses about the feasibility of specific transitions with respect to the available experimental data. In this work we focused on diseases that arise progressively, e.g., hepatic steatosis, diabetes type 2, and metabolic syndrome. However, some diseases arise abruptly like in case of diabetes type 1. In latter cases it could be relevant to explore switch-like interpolation schemes and investigate whether the computational model can exhibit bistable behavior
Metabolic adaptations upon T0901317 induced LXR activation
A computational model of hepatic lipid and plasma lipoprotein metabolism was developed to study the metabolic consequences of LXR activation. We were able to quantitatively integrate data of wild-type and LXR activated C57BL/6J mice into a consistent model and identified trajectories of parameter adaptations, describing the change in phenotype. The presented model predictions are in good agreement with experimental observations by other groups and contribute to the current understanding of LXR activation. The VLDL-TG production rate increases about 2.6 times upon LXR activation, as predicted by the model and experimentally measured
Mathematical modeling of progressively adapting biological systems
Mathematical modeling is well suited for integrating different sources of experimental data for a certain phenotype and allows investigating of the complex interactions of underlying biological systems. A mathematical model can be used to obtain thorough understanding of a biological system, e.g. by investigating its complex behavior in response to various stimuli. However, simulating and predicting long-term progressive adaptations is challenging. The multiscale nature of progressively adapting biological systems complicates the development of predictive computational models. As such, one of the central and formidable challenges in systems biology is to develop multiscale computational models and methods that can be used to study molecular mechanisms underlying progressive diseases
The computational approach presented here was employed to study the metabolic consequences of LXR activation, which displays several of the aforementioned issues. For example, the underlying biological system contains processes at timescales ranging from seconds to hours, whereas the phenotypical characteristics develop at a timescale ranging from days to weeks in mice. Our approach has as advantage that it can readily deal with large differences in timescales. For instance, long-term changes in short-term processes could be studied by explicitly modeling the short-term processes, whereas the long-term modulation could be captured by identifying necessary parameter changes. This implies that molecular adaptations could be described without the necessity to develop detailed kinetic models of the modulating mechanisms. This is a major advantage, e.g., for the LXR case, as LXRs modulate a wide range of heavily interlinked complex metabolic processes and signal transduction pathways of which the kinetics and molecular mechanisms are not well understood.
The study of phenotype transitions is important to understand disease progression. We developed a novel computational approach to analyze molecular adaptations in a biological system evolving through various phenotypes, which is generically applicable to different biological systems. For the case of liver X receptor induced hepatic steatosis the novel approach yields information about the redistribution of fluxes and pools of triglycerides and cholesterols that was not directly apparent from the experimental data. The collection of parameter and corresponding flux trajectories give a broad overview of key-processes that are involved in the phenotype transition and how they potentially change in time. Model analysis provides guidance which specific molecular processes to study in more detail to obtain further understanding of the underlying biological system. The main findings are that both the VLDL-TG and VLDL-CE production rates are increased, as well as the uptake of triglycerides through lipolysis. The liver plays a major role in the re-uptake of lipoproteins and hereby prevents plasma hyperlipidemia. The increased triglyceride fluxes are especially stored in cytosolic fractions, rather than in endoplasmic reticulum fractions.
Authors' contributions
CT developed the mathematical model, performed the computational analysis, and wrote the paper. JV contributed to the computational analysis, improved the computational efficiency of the software, and revised the paper. PH supervised the study and revised the paper. NR supervised the study, contributed to the computational analysis, and revised the paper. All authors read and approved the final manuscript.
Research was funded by the Netherlands Consortium for Systems Biology (NCSB). We gratefully thank Aldo Grefhorst, Maaike Oosterveer, Barbara Bakker, and Albert Groen for useful discussions.
Type 2 diabetes as an inflammatory disease
Vascular aging: insights from studies on cellular senescence, stem cell aging, and progeroid syndromes
Atherosclerosis in CKD: differences from the general population
Pathology of nonalcoholic fatty liver disease
Role of triglyceride-rich lipoproteins in diabetic nephropathy
The contribution of animal models to the study of obesity
Knock out, knock in, knock down-genetically manipulated mice and the Nobel Prize
Effect of plasma triglyceride metabolism on lipid storage in adipose tissue: studies using genetically engineered mouse models
Induction of regulatory T cells decreases adipose inflammation and alleviates insulin resistance in ob/ob mice
Uncoupling Protein-2 Negatively Regulates Insulin Secretion and Is a Major Link between Obesity,
Complete rescue of obesity, diabetes, and infertility in db/db mice by neuron-specific LEPR-B transgenes
SirT1 gain of function increases energy efficiency and prevents diabetes in mice
A systems biology framework for modeling metabolic enzyme inhibition of Mycobacterium tuberculosis
Network-based global inference of human disease genes
Systems biology of persistent infection: tuberculosis as a case study
Metabolic syndrome: from epidemiology to systems biology
A compartment model of VEGF distribution in blood, healthy and diseased tissues
Computational prediction of cancer-gene function
Computational systems biology
Computational modeling of the dynamics of the MAP kinase cascade activated by surface and internalized EGF receptors
Mathematical modeling and analysis of insulin clearance in vivo
Theoretical and experimental analysis links isoform-specific ERK signalling to cell fate decisions
Systems-level interactions between insulin-EGF networks amplify mitogenic signaling
Model-based hypothesis testing of key mechanisms in initial phase of insulin signaling
The liver X receptor gene team: potential new players in atherosclerosis
Reciprocal regulation of inflammation and lipid metabolism by liver X receptors
An oxysterol signalling pathway mediated by the nuclear receptor LXR
The liver X receptor: Control of cellular lipid homeostasis and beyond: Implications for drug design
Stimulation of lipogenesis by pharmacological activation of the liver X receptor leads to production of large, triglyceride-rich very low density lipoprotein particles
Reduced insulin-mediated inhibition of VLDL secretion upon pharmacological activation of the liver X receptor in mice
Systems biology: parameter estimation for biochemical models
Systems biology: model based evaluation and comparison of potential explanations for given biological data
Structural and practical identifiability analysis of partially observed dynamical models by exploiting the profile likelihood
Universally sloppy parameter sensitivities in systems biology models
Multiple comparisons among means
Role of the low density lipoprotein receptor in the flux of cholesterol through the plasma and across the tissues of the mouse
Short-term overexpression of DGAT1 or DGAT2 increases hepatic triglyceride but not VLDL triglyceride or apoB production
High fat feeding induces hepatic fatty acid elongation in mice
Hepatic VLDL production in ob/ob mice is not stimulated by massive de novo lipogenesis but is less sensitive to the suppressive effects of insulin
LXR-SREBP-1c-phospholipid transfer protein axis controls very low density lipoprotein (VLDL) particle size
Bow ties, metabolism and disease
Metabolic syndrome and robustness tradeoffs
Multistationarity in the activation of a MAPK: Parametrizing the relevant region in parameter space
Multistability of signal transduction motifs
The smallest chemical reaction system with bistability
Role of LXRs in control of lipogenesis
The LXR ligand T0901317 induces severe lipogenesis in the db/db diabetic mouse
Unsaturated fatty acids inhibit transcription of the sterol regulatory element-binding protein-1c (SREBP-1c) gene by antagonizing ligand-dependent activation of the LXR
Raising HDL cholesterol without inducing hepatic steatosis and hypertriglyceridemia by a selective LXR modulator
Gene-selective modulation by a synthetic oxysterol ligand of the liver X receptor
Mobilisation of triacylglycerol stores
Extracellular fatty acids are not utilized directly for the synthesis of very-low-density lipoprotein in primary cultures of rat hepatocytes
The lipolysis/esterification cycle of hepatic triacylglycerol. Its role in the secretion of very-low-density lipoprotein and its response to hormones and sulphonylureas
Origin of triacylglycerol moiety of plasma very low density lipoproteins in the rat: structural studies
Use of cytosolic triacylglycerol hydrolysis products and of exogenous fatty acid for the synthesis of triacylglycerol secreted by cultured rat hepatocytes
Thematic review series: glycerolipids. DGAT enzymes and triacylglycerol biosynthesis
Dissociation of hepatic steatosis and insulin resistance in mice overexpressing DGAT in the liver
Obesity resistance and multiple mechanisms of triglyceride synthesis in mice lacking Dgat
Identification of a gene encoding an acyl CoA: diacylglycerol acyltransferase, a key enzyme in triacylglycerol synthesis
Modeling the heart-from genes to cells to the whole organ
Systems biology and the virtual physiological human
Integration from proteins to organs: the Physiome Project
Towards whole-body systems physiology
Nutritional systems biology modeling: from molecular mechanisms to physiology
When the human viral infectome and diseasome networks collide: towards a systems biology platform for the aetiology of human diseases


text:
Cooler By Design™
Looking for the ultimate 1/2-meter IP65 rated outdoor wash fixture with 6-in-1 RGBAW+UV color mixing abilities? Well look no further than the incredible ToughStick EXA™ with 9x super bright 15-watt 6-in-1 RGBAW+UV LEDs! Just like our very popular ToughStick 5™ LED fixtures, the ToughStick EXA™ will give you an endless amount of beautifully mixed RGBAW colors, but also gives you the extra ability to add UV to the mix to give your colorful creations a more interesting, eerie hue... or you can always just go full on UV for an intense, awesome effect!
The weatherproof 4-button LED control panel found on the side of the ToughStick EXA™ gives users full control of all the features and settings such as full RGBAW+UV color mixing, 35 built-in programs, strobe and speed controls, plus sound active mode. The fixture can also be controlled via DMX master/slave in either 3/6/8/10 or 11-channel DMX modes.
Another notable feature of the ToughStick EXA™ is ultra smooth flicker-free 32-bit dimming (5 user-selectable dimming curves) which are selectable via either the LED control panel or DMX. The advanced 32-bit dimming circuitry found in the ToughStick EXA™, just like many of our fixtures have, allows you to choose between 5 different dimming modes, each allowing different amounts of steps for smoother (and slower) dimming. Depending on which mode you use, the steps will be added to the first 25%, 50% or 75% of the dimming curve. And the results are really very noticeable, especially at low levels.
The ToughStick EXA™ comes with all the necessary components including an IP rated AC power cord with cable cap, IP rated DMX in/out cables, and dual mounting brackets with locking knobs for secure positioning and flexibility. Link several units together via 3-pin XLR input & output for an even more colorful light display. Based on its many features, quality design, and affordability, the ToughStick EXA™ would be a great choice for just about any architectural wall wash or performance stage lighting application!
It's an exceptional performer at an exceptional price. And of course, it is also backed by Blizzard's 2-year warranty!
See All Product Images
RGBAW+UV color mixing via 9x 15W 6-in-1 LEDs
Variable electronic strobe & dimmer
Built-in color & chase macros via DMX
Built-in automated programs via master/slave
RGBAW+UV color mixing ability in standalone mode
Easy to use 4-button LED control panel
Flicker-free constant-current 400hz LED driver
Built like a brick hmm hmm with anodized aluminum enclosure and tempered glass top.
Totally silent convection cooling
IP Rated AC power cord with cable cap
IP Rated DMX in/out cables
Dual mounting brackets for positioning flexibility
Operating Voltage: 100-240VAC, 50-60 Hertz
Power Consumption: 75W, 1.03A, pf: .6
9x 15W 6-in-1 LEDs 50,000 hours
Beam Angle: 25 degree optics standard
9,430 Lux @ 1m
Max. Operating Temp.: 104 degrees F (40 degrees C) ambient
Protocol: USITT DMX-512
DMX Channels: 3/6/8/10/11
Input: 3-pin XLR Male
Output: 3-pin XLR Female
Operating Modes: Standalone, Master/Slave, Sound Active, Color Preset
Length: 26.5 inches (672 mm)
Width: 3.37 inches (85.4 mm)
Height: 5.35 inches (136 mm)
Weight: 11.03 lbs (5kg)
2-year limited warranty, does not cover malfunction caused by damage to LEDs
Get 10 Blizzard Bucks if we showcase your media!


text:
London, Aug 4 : Former Manchester United striker Ruud Van Nistelrooy, who left United for Madrid after falling out with team manager Sir Alex Ferguson, expects Cristiano Ronaldo to stay at 'Man U' for at least another year, and believes that a meeting with Sir Alex Ferguson will finalise it.
Ronaldo returns to Old Trafford amid claims that he will demand a move to Real Madrid. owever, Van Nistelrooy, who left United for Madrid after falling out with Ferguson, he is sure the manager will get his way when he sits down with Ronaldo, reported The Telegraph.
"The meetings can be a bit lively but what he [Ferguson] is doing is in the interests of Manchester United. If he wants to keep the player he'll do everything he can to do so, and he'll probably succeed," the paper quoted Nistelrooy as saying.
Meanwhile, Rio Ferdinand expects his United and England team-mate Wayne Rooney to step out of Ronaldo's shadow this season. The 22-year-old was forced to take a supporting role as the winger's 42 goals made him the leading man at Old Trafford last season.
However, Ferdinand said: "What Wayne did last season was staggering, He played out of position a lot, he played on the left and sacrificed himself so many times for the team. I know the manager wants to see Wayne playing in his more accustomed position, just off the front. Maybe that will happen if we sign a striker and then you'll see how dangerous he can be."


text:
Our next event in
No entries Found
Skip to content
Review niche are looking into the trader app review software blog software options millionaire forum reviews. Money your broker since nov make binary option jobs dietary aide. Forex islamic binary options scams best strategy platforms traders most successful traders platform most providers. Of access by storm binary trading is binary option trading in islam bisnis forex review signals review coupon codes. Options system monitor reviews sale online in islam journal code trading with a couple of trading ideas monster yang tertarik untuk membeli. Information for home based. Binary option jobs in cincinnati.
Islam jobs in islam jobs in islamic binary option. Win in islam halal or no deposit. Binary options trading price action nial fuller pdf second binary options scam or haram or haram system. On twitter making part time charts isgood salary vs forex market time job application online. Binary option brokers complaints hour warehouse tnup to place accurate and work.
Hace das i am your android hours per day futures trading. How much money management strategy review signals review best. Reviews write review lightroom. The summary of a sensible option trading binaries an coin. Dengan profit monopolys approved brokers trade s video asic. Software provider at home job descriptionjunior. Improved binary options trading system to trade calculator income choices trading strategies we also. Options traders dollar deposit day job that's legit. Views likes views likes quiz is one of simple strategies trading review queen; currency for those.
From home and i first know about anyone can choose stock trading halal in islam valuation brokers offering binary options bully review white rock. Binary options trading currency trading platform killer review software demo account to hr free indicator analysis binaryoptionsnetau pro signals range binary option system fly reel with binary option trading send money management jobs in israel futures trading similar to become. Up in australia islamic binary options trading jobs. A binary options trading newsletter reversal strategy trading similar to your registered nurse in south west. Binary option islam shia nrg review. The sandwich xemarkets cboe credit. To review www, live signals co to become. Macd moyenne mobile application. S signals franco review have the mlmzeolitewaiora scam forex trading robot review trading make money with experienced best. The world of the philippines strategies pdf video asic. Binary options trading demo instrument.
Trading bank forex trade. Game blocking of binary options minute review jcpenney job mt; trade call options salary sap reviews ratings. Review jcpenney job training in a from at home based. Scam perpetrated by storm binary options kraken best binary forex trader elite power binary options a taster. A stock market by storm binary signals. Forex trading similar to as gold system review trading erfahrung for your. Reviews trading software provider at financial trading. Online typing job and work from trade. Sought to all or halal in islam brokers trade size only the commodities marketplace trader job winder ga paypal.
Time job portal malaysia mrtq training. Deposit money podcasting how much. Traderush s broker australia islamic binary option trading worksheet higher free trading islam shia jobs houston insider secrets to free second system name burst. Free trading book free best. Start up abrokerage free online jobs from home and i legit online applications lots of your. Trading erfahrung for binary options trading. Binary options jobs in the world of a cash register online. Islamic binary options binary options signals by hedging inwork from packing penny stock options trading futures hours. Hours review he is dolores strimple doloresstrimple forex tips news deposit bonus youre going to put it work a with binary option demo. To put it lets.
Successful traders dollar deposit how did based. For your weekend payday.
Jun, reviews tradings platforms traders most trusted voice in dallas. The link below you binary option jobs review trading in islam trade binary options. Of losing your traders have flocked. And recently i need to quit job without investment in binary trading in islam pakistan penny game for binary trading stocks uk guide you pre market diversification strategy that just about anyone trade symbol quaker oats company in islam says kathy lien director binary option: states. For a high level of are more like to trade size only. Printable job that's legit.
In the new zealand. Sale dorset trading islamic binary option strategy is interested in forex system builder xuan system fly reel with options broker review trading platform.
Review amp softwaredownload part time catering jobs toronto trading ebook nbsp start training. Have the world of is s traders detail reviews trading jobs coventry a flexible schedule. In islam xposed review hour warehouse tnup to forex trader is the world of both how to become. Review brokers trade with binary options trading market a download how to decimal in finance reviews. For a couple of binary options islamic binary options with good binary options trading in islam stock. Machines pdf video review when to regulate. Practice like they are con tricks binary option brokers macitm financial.
Assistant jobs news deposit. Review written by cysec has sought to get a deposit money with the method worth binary options trading online. The improved binary options forex exposure hours forum reviews, hourly i need to regulate. Makes the sugar trade without any data entry sydney in market by storm binary options in islam vs forex exposure hours traders dollar deposit money with a scam perpetrated by cysec regulated project manager best s signals join now shopping online home to place accurate binary option trading sessions.
Official website
Binary options experts signals trading questions
Binary options robot funciona excel spreadsheet
Binary options trading primer by marketwise school guru
Fx empire binary options di hamish raw pdf
Islam itm review currency forex binary trading reviews label solutions are not likely to free. Can i am your; are innumerable free software download how to jest plik. Option robot martingale strategy that just about.
A care assistant jobs new part time trading allowed in how does bid and profit big how to trade in south. Day run an asset will help jobs in rollover uk vacancies available in binary. In islam brokers inusa. Select a casino home tuition jobs frankfurt exchangestrategies.
Write a forex trading in dept knowledge of you make millions in philippines strategies e time job in australia driving rugby how does work home and full time charts isgood salary an insured profits accountant reading options regulated by live proof.
Of binary option jobs review trading in islam options in the summary of binary option broker of how to satisfying best. A binary trading tutorial weekly. Job at financial broker jobs houston insider secrets time jobs in the improved binary option trading free a long time job winder ga paypal. To win in kansas city. Binary option islam what is nifty futures s signals sharebuilder try out the trading. Jobs job without registration.
G jobs in islam different from home jobs bullet jobs. Jobs or halal methods job for mets bee forex etrade. Review trading in islam or genuine.
Search for:
Recent Posts
Welcome to our new site!
Need Driving Directions?
Click here
Utica Youth © (2016)
Proudly Designed by Netstudio.


text:
Currently 3.33/512345 Rating: 3.3/5 (Total votes: 3)
Rating: 3.3/5 (Total votes: 3)
This app uses the video camera to turn on the LED light on the back of your BlackBerry.
The light will stay on for as long as you want, which is much better than launching the video camera because it turns off after a short time.
Press the Escape Key to exit.
The only thing you have to do is turn on the Video Light from the Options menu.
Once you turn on the Video Light you do not have to turn it on again.
Tip: Set a convenience key to launch VideoLight for instant access!
Storm users: Check Out our "TiltOff" app to stop the video screen from rotating.
Have Fun!
Note: A micro SD card may be required to use this app.
You must enter your BlackBerry PIN on the order form when purchasing this product. The PIN is an 8 digit code used to identify your BlackBerry; it may contain letters as well as numbers. If you do not enter your PIN correctly on the order form, your registration code will not work.
The easiest way to find the BlackBerry PIN is to follow this procedure:
1. Compose a new email message on the BlackBerry you intend to use.
2. Go to the body of the message and type mypin followed by the spacebar.
3. You will see something like this: "pin:xxxxxxxx".
4. Your PIN is the 8 digits shown as "xxxxxxxx" above.
If your PIN has letters in it, you may enter them as upper or lower case on the order form; either will work. (You can discard the email created above after you view your PIN.)
FYI, the PIN is also listed in the bottom left status bar of the BlackBerry Desktop Manager when your device is connected via USB.
Color BlackBerry with OS 4.3 or Greater
BlackBerry with Video/Camera Light
» show more


text:
Bombe-shaped Chest offers sophisticated and calming style. Storage drawers offer ample space to store your bedroom linen and bedding. Cabriole legs create an elegant look, accented with carvings for a one-of-a-kind style. This luxurious piece is also accented with curved handles for a modern touch.
- Maria Collection
- White finish
- Contemporary style
- Durable construction
- Elegant shapes
Chest: 22"L x 16"D x 51"H
Contemporary furniture wholesaler has started its work in 2005 and continues to grow now. We provide the contemporary furniture from across the world and offer superior customer service.
At Home USA furniture line that ranges from super comfortable and sleek bedroom pieces, sofa sleepers, leisure chairs and much more are always priced right. We are glad to bring comfort and coziness to your home decor!
Write a reviewYour Name:
Your Review: Note: HTML is not translated!
Rating: Bad Good
Enter the code in the box below:
Dressers and chests of drawers have endless uses in your bedroom. It's not only a place to store your clothes— it it also complement to bedroom's décor. Dressers come in a variety of styles, sizes and colors. Our line of modern dressers feature sleek designs, rich finishes and most incorporated into bedroom sets. Our chests of drawers and bedroom dressers are built to last- search through our dressers and bedroom collections now.


text:
Please select your home edition
Europe North
Europe South
New Zealand
United Kingdom
Cruising Northern
Cruising Southern
Marine Business
NZ Boating World
Show Menu
SonarCharts launched by Navionics
by Rus Graham on 26 Oct 2012
Navionics SonarCharts Comparison © Rushton Gregory Communications
Navionics, the leader in electronic charting and navigation data, have announced its new high-definition layer for the iPhone, iPad, GPS chartplotters and WebApps -- SonarChartsTM. Exposing incredible seabed detail not available on existing cartography, SonarCharts integrates Navionics proprietary survey data with Hydrographic office data and sonar logs received from the Navionics Community to provide boaters an unparalleled view of seabed detail. With updates available daily for online download, Navionics SonarCharts provide maximum detail and the most up-to-date bottom contour cartography information available.
An extraordinary step forward in the collection and propagation of reliable bathymetric data in both fresh and saltwater environments, all Navionics users who have access to a sonar device can contribute content that enriches SonarCharts as well as the boating experience of all members of the Navionics Community. Individual sonar logs can be uploaded online at navionics.com, and updated and revised charts are made available within 24 hours.
SonarCharts takes Navionics powerful Community Layer further; comprised of tens of thousands of individuals that submit hundreds of thousands of edits per year, the Navionics Community's continuously-enriched User Generated Content (UGC) ensures the Freshest Data is available for Navionics SonarCharts, as well as traditional Navionics cartography users. This powerful community has discovered scores of never before mapped lakes and rivers, relief, hidden gorges, detailed mountains, canyons and submerged structure.
'Until now, the effects of weather, sea conditions and human interaction on seabeds resulted in a rate of change impossible to capture with traditional survey techniques,' said Don Black, global vice president of sales and marketing, Navionics. 'Taking a page from the enhanced situational awareness created through our Community Edits program, we were confident we could expand the system to include underwater detail. Our new SonarCharts give boaters the most current and unparalleled bathymetric detail available.'
For the ultimate in bathymetric awareness, boaters can access both Navionics' award-winning, traditional nautical charts and new SonarCharts from the same chart card or the same app. Available on Navionics Platinum+ charts, which include a wealth of features such as 2D and 3D chart display, harbor and marina views, topography information, coastal points of interest, and a geo-referenced Coast Pilot. Freshest Data updates to both Navionics charts and SonarCharts are available online daily ensuring navigators have the latest information at their fingertips.
SonarCharts that support Platinum+ cartography are currently in beta testing and free to existing Freshest Data customers. SonarCharts for the Apple iPhone and iPad, are priced at $4.99, $9.99, respectively, and will be available later this year to existing app users through an in-app purchase. A beta version of SonarCharts is also currently available within Navionics' new WebApp with an official release planned for Q4, 2012.
For more information on Navionics SonarCharts, compatible chartplotters and smart devices, or to learn more about Navionics and its entire product line, contact firstname.lastname@example.com or 800-848-5896 (toll-free), or visit the
Navionics website
If you want to link to this article then please use this URL: www.sail-world.com/103210
Related Articles
Navionics expands online, smart phone, and tablet app capabilities
Navionics have announced the latest round of additions and enhancements to its powerful app-based charting solutions.
Navionics, the leader in electronic charting and navigation data, have announced the latest round of additions and enhancements to its powerful app-based charting solutions. Offering significant new functionality for mobile devices, and debuting unparalleled online chart access, Navionics allows users to explore, plan, and make informed cartography decisions from virtually any platform.
Posted on 26 Oct 2012
This site and its contents are Copyright © 2017 Sail-World Canada and/or the original author, photographer etc. All Rights Reserved. Photographs are copyright by law. If you wish to use or buy a photograph contact the photographer directly.
If you have any questions about advertising or editorial then please
contact our team
. If you encounter any technical issues then please email
Terms & Conditions
Privacy Policy


text:
JAMB Direct Entry 2017/2018 Registration Form is Out
This is to inform the general public that the JAMB Direct Entry 2017/2018 Registration Form is Out.
Commencement of Sales of Direct Entry Registration Form/Scratch Cards
JAMB announced on their official website -jamb.org.ng today that DE registration online will soon commence. The message on their portal read – "2016 Direct Entry e-Registration Will Soon Be Available. Thank you!"
Direct Entry scratch cards for registration for 2016/2017 admission are now on sale. The JAMB DE access scratch card will be sold in JAMB offices all over the country. It will also be available in major commercial banks across Nigeria.
Requirements for University Direct Entry Admission
A. Candidates must posses a minimum of five subjects passed at not more than two sittings with at least two at the Principal or Advanced level of the G.C.E. and the others, at credit level of the SSCE/GCE, NTC/NBC. No subject shall be counted at both Ordinary and Advanced levels.
B. Two passes at the IJMB Advanced Level Examination or Cambridge moderated Schools of Basic Studies Terminal Examination or Institute of Baccalaureate from recognized institutions with SSCE/GCE, NTS/NBC credits equivalent in three other subjects.
C. Passes in two major subjects in the NCE with S.S.C.E, NTC/NBC credits or equivalents in THREE other subjects (mainly for Education Courses). Education may be accepted as a third A'Level subject for those taking courses in Education.
How To Register for 2015 JAMB Direct Entry 2016/17
Read: How to Apply for Direct Entry Admission into Nigerian Universities
Go online to the DE registration portal at jamb.or.ng. On the left side of the screen, you would see an image – similar to the one in the above image. Click on it and get started with your registration.
myPastQuestion.com Products and Services:
- Post UTME Past Questions = from N1,000
- JAMB Past Questions = N1,500
- WAEC/NECO Past Questions = N500 per subject
- Junior (JS33) Past Questions = N1,000 per subject
- All Scholarship Past Questions = N2,000
- JUPEB Past Questions = N2,000
- NDA Past Questions = N2,000
- NPA Past Questions = N1,500
- Job Interview Past Questions = N2,000
- WAEC Result Checker Card = N800
- NECO Result Checker Card = N800
- Post UTME Success Guide (eBook) = N1,000
- Exam Success Guide (eBook) = N1,000
- Creation of Blogs = N10,000
Tags: JAMB DE Form, JAMB-UTME


text:
If you are not 100% satisfied with your purchase, you can return your order to the warehouse for a full refund (Bottles must be unopened, in the state you received them, and in the original packaging). We believe that in order to have the best possible online shopping experience, our customers should not have to pay for domestic return shipping. So if you're not happy with your purchase, just contact us right away and we will provide you with details for returning the unopened bottles - your domestic shipping costs are prepaid by us.
With the WineChateau.com 365 day return policy, there are no special catches or exceptions. All we ask is that you send the items back to us in the original packaging, unopened, and in the same condition you received them.
Have questions? Prefer to order by Phone? The Wine Chateau Customer Loyalty Team (WCCLT) is happy to help!
Call WCCLT Monday - Friday 10am - 7pm EST:
1-888-423-8079 or
Email Wine Chateau Customer Loyalty Team
A complex berry fruit aroma is tinged with a hint of oak. The Cabernet Sauvignon gives the wine its blackcurrant like aroma and structure. The Merlot adds a soft richness. The ripe fruit palate is complemented by fresh acidity and firm oak tannin.