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For East Jefferson, it is one of the biggest baseball games in almost a decade.
And for Edna Karr, it is the biggest baseball game … well, ever.
East Jefferson will host Karr on Tuesday at 4 p.m. in a Class 4A regional playoff game.
The winner of the all-New Orleans area battle advances to the quarterfinals.
The Warriors (21-10) haven't been to the quarterfinals since 2003. The Cougars (22-1) won their first playoff game in school history in the first round.
"It will be the biggest crowd we have had in some time," East Jefferson coach Brent Whittington said. "It's huge. Two metro area public schools having a chance to go to the quarterfinals would be a big boost for either program."
Despite the magnitude of the game, Karr coach Donnie Russell is trying to get his team to treat it like just a regular game. But having led his team to the best season in school history, it's not.
"Every game going forward is a big game," Russell said. "We are in unchartered territory. We know there is a lot at stake, but we are not going to get caught up into all of that. We see it as just another game. We are not going to strategize any differently, and we will go through our same routine."
Russell shouldn't have any trouble motivating his team. Karr's only loss this season was 10-7 to East Jefferson.
"We're returning to the crime scene," Russell said with a laugh before focusing on what East Jefferson excels at.
"The biggest thing about them is that they are just so fundamentally sound," Russell said. "They don't do anything to beat themselves."
East Jefferson, a No. 26 seed, went on the road and knocked off No. 7 seed Franklinton in the bidistrict round to get to the regional round.
"That was a great upset for us," Whittington said. "We had great pitching and that was obviously the difference in the game. They battled all night long and kept those guys off balance."
Junior pitchers Jimmy Prieur and Dominic Giovingo combined to get the win over Franklinton. Those two pitchers, along with junior Austin Hibbs and sophomore Brad Randazzo, have played a key role in what has been somewhat of a surprising season for the Warriors.
They graduated nine seniors from last year's team and returned just two starters.
"We knew we were going to be young and inexperienced," said Whittington, in his eighth season as head coach. "But we also knew that all four of our pitchers would be coming back. So we knew we had to rely on pitching and defense. We feel like the last few weeks we have been playing our best baseball of the season."
Prieur, who is batting .400 to go with his 33 RBIs, leads East Jefferson, along with Giovingo (.377) and senior second baseman Jonathan Manos (.363).
Karr is led by sophomore sensation Tyree Thompson, who is 11-0 this season with 114 strikeouts. He struck out 10 last week and also drove in the game-winning run that gave Karr its first playoff victory last week against Plaquemine.
"He throws really hard and has a live arm," Whittington said.
D'Monte Carter (batting over .500), third baseman Tyler Reid, catcher D'Andre Williams and center fielder Jarid Montgomery lead the Cougars. But it's what the Cougars do once they get on base that gives Whittington the most concern: Karr has stolen close to 200 bases this season.
"They swing the bats well and put a lot of pressure on you when they get on base," Whittington said. "You have to try to keep them off the bases, because when they get on, they can give you some headaches."
The winner advances to the quarterfinals to play the winner of Tuesday's Crowley-West Ouachita game.
East Jefferson is chasing its fourth state title and first since the school won it all in 1971, 1972 and 1978.
The school is also looking to continue what has been a stellar athletic school year.
East Jefferson won a state title in football (beating Karr in the title game) and also reached the title game in boys basketball.
"With the athletic success we have had, it would be a great way to cap off the school year," Whittington said.
Follow Rod Walker on Twitter @rwalkeradvocate


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A Polish television recording of the concert at the Kalisz Piano Festival shows the trios brilliance and humour, impressively accentuated by the facial expressions and body language of the three musicians. In addition to the eighty-minute concert, the DVD presents a lengthy interview with the ensemble recorded in Moscow in the early summer of 2006.
10 years became the call loudly to publish a live DVD of Moscow Art Trio. Because the music is fantastic, the visual aspect absolutely signifies an extension of the hearing experience. The subtle and emphasised humor of the trio comes with the DVD only properly to carry and makes clear that they count to the most thrilling formations of the new jazz.
The concert of the Polish Kalisz festival contains the classics of the Moscow Art Trio who were played in among other things on the legendary CD HAMBURG CONCERT. The concert is complemented with a 18-minute test recording and an interview of the musicians.

subset: commoncrawl


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Sunrisers' Hyderabad Shikhar Dhawan seems to be smitten by a certain someone in his life and its not his wife Ayesha.
The opening batsman recently shared a picture of him along with his pet dog named 'Terri' with this caption.
My whole tiredness goes away the time I enter my home and get lots of love from https://t.co/g5g33Tqo6r it!! pic.twitter.com/Hq9IkY51yF— Shikhar Dhawan (@SDhawan25) May 16, 2016
Apparently, the canine seems to drive all his tiredness away.
Also watch video: Shikhar Dhawan, Yuvraj Singh and Sunrisers sing 'victory song'
Dhawan has scored 402 runs from 12 matches in the Indian Premier League 9 season and is the 7th highest run scorer. His highest score is an unbeaten 82.
Shikhar Dhawan. Pic/ AFP


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Escape Fairy Series 4
Jungle Owl Escape Use Mouse Only.Ensure to use only your mouse to play jungle owl escape game. The owls do not sleep at night, and completely nocturnal in habit. It has been trapped and captured inside a tree hole. Your responsibility is to help the owl escape from the hunter's cage. The sound and animation are nteresting in this game. Click for More free escape games
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Mp3 Player Disguised As A Lego Brick
Are you a fan of Lego who happens to like music as well? You're in luck. This interesting item below is an Mp3 player disguised as a Lego brick, or the other way around depending on how you see it. Although these Mp3 players are not the official merchandise of Lego, they sure look like the real thing and will definitely be one of those must-get items for Lego fans out there.
The Lego Brick Mp3 player does comes with a waft of novelty and if you take a closer look you will notice that the controls are cleverly incorporated into the design as well by having the stacking bumps take on the role of the control buttons.
Sadly and unexpectedly, the player does not come with internal memory at all, meaning that you'll have to get a separate microSD card to store the songs for playing with the device. Apart from that, the rechargeable Lithium-ion battery will run for a reasonable 6 hours.
The Homade Lego Mp3 player retails for US$46 at Homeloo.
As of post time the players have all been sold out. Hopefully they will be restocked very soon.
via technabob


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Extension Associate, Health
College Station, Texas 77843-2251
phone: 979-845-3850
fax: 979-845-6496
e-mail: email@example.com
Janet Pollard is an Extension Associate with the Texas A&M AgriLife Extension Service, working in the areas of health promotion and health education for over 14 years. Her primary areas of interest have been in immunizations, maternal and child health, fitness (particularly among the older adult population), and the National Network for Health (connecting Extension health professionals with web-based health resources, as well as face-to-face across the nation). Currently, Janet's primary focus is to provide public information on current health topics through research and development of the monthly HealthHints newsletters.
Janet's educational background includes a Master's degree in Public Health from the University of Texas–Houston Health Science Center, a Bachelor's degree in Psychology from Texas A&M University, and a Writing Specialization, also from Texas A&M University. Janet has been awarded the Superior Service Award and been given award recognition for her work with the Shots across Texas Immunization Campaign during her service with the Texas A&M AgriLife Extension Service.
Last updated: March 26, 2015


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The Top 8 Things WWE Wants You To Forget About WWE
The planet from expert fumbling has constantly progressed over times. There have actually been lots of adjustments created that WWE fans might never ever view once again, including:
Some changes in wrestling have emerged of necessity and also others have come as a result of natural evolution. Nevertheless, there are still components of wrestling that a lot of enthusiasts skip.
Listed below are actually 8 traits wrestling followers will definitely never ever find in the WWE once again.
1. Randy Orton's trademarked punting zing was a super-finisher that enthusiasts were utilized to seeing him make use of in the ring. Nonetheless, the World Fumbling Enjoyment outlawed the technique because of 'blast awareness.'
2. Bra & Underwear matches used to become a staple of the WWE, however after the promotion applied a PG ranking to be much more family members welcoming, the scantily dressed pet cat battles were no longer. The fumbling world has also moved to certainly not only embody their women wrestlers as eye-candy.
3. The Great Khali founded the Punjabi Penitentiary match, which contains 2 sizable bamboo crates. Nevertheless, after The Great Khali's parting off the WWE, that is actually extremely unlikely that fans will certainly see these bamboo cages once more.
4. Seth Rollins' visual stamp manoeuvre used to be one of his staple finishers. The completely fierce step included stomping on the back of one's head, that makes this no surprise that this was at some point outlawed. Nonetheless, Rollins showed the action had not been prohibited because of safety and security problems, yet given that the technique was also just and easy for little ones in order to get affected by it.
5. While the band could still observe safer variations of the relocation, the piledriver has actually been disallowed not away from measure yet from event. At SummerSlam 1997, Owen Hart's piledriver deviated for the worse as 'Stone Cold' Steve Austin ended up momentarily paralysed.
6. In 2010, WWE proclaimed that this would certainly be actually 'doing away with the use of folding chairs or even props to hit an opponent on the scalp.' While it may take place sometimes, wrestlers go through penalties or even suspension. These actions utilized to be usual in the ring, however resulted in various traumas.
7. Blading, where a wrestler utilized a small razor blade to draw blood, was actually used as opposed to altercating relevant from bleeding. Nonetheless, WWE outlawed the technique to steer clear of shedding possible enrollers as a result of the self-mutilation on display screen.
8. Snake pit matches observed the accorded group bordered by blazing wall surfaces from fire. While snake pit matches were actually pretty the phenomenon, setting a person ablaze to end a fit doesn't necessarily follow to the PG ranking.


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- Salivation
- Salivation Sal`i*va"tion, n. [L. salivatio: cf. F.
salivation.] (Physiol.)
The act or process of salivating; an excessive secretion of
saliva, often accompanied with soreness of the mouth and
gums; ptyalism.
[1913 Webster]
Note: It may be induced by direct chemical or mechanical stimulation, as in mastication of some tasteless substance like rubber, or indirectly by some agent which affects the whole system, as mercury compounds. [1913 Webster]
The Collaborative International Dictionary of English. 2000.


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While national oil companies (NOCs) in the region have traditionally been slow in innovating, would the low oil prices convince them of the need to invest in new technologies? Dr Walid Fayad, Executive Vice President at Booz Allen Hamilton MENA, gives us the low-down on how the O&G sector is reacting to this crisis.
In general, oil fields in the region are still quite nascent with respect to digitization. At this time, it is imperative that companies that have invested in the relevant infrastructure also invest in the critically important analytics and visualization layers to tie the data together. For example, some companies have already installed the latest metering and well surveillance equipment. However, this equipment needs to be coupled with strong analytics on the back end to help predict well failure in order to avoid both direct costs in the form of costly downtime and indirect costs due to suboptimal work over rig utilisation. These investments can help NOCs turn their wealth of information into meaningful insights, reduced costs, and increased cash flow.
So, what is needed now is not necessarily an investment in new technology, but rather optimizing on the investments that have already been made. With budget cuts being felt in every sector, NOCs cannot afford white elephants. At the same time, if they stop making targeted investments, they risk falling behind technologically. So we will see smarter investments aimed at getting more from what is already there. At any stage of technological maturity, a relatively incremental investment in analytics can significantly improve the status quo. For example, the majority of wells being drilled today are collecting real-time drilling mechanics data (torque, weight on bit, rotation, etc.) When properly aggregated and analyzed, this data can be used to greatly improve drilling speeds and reduce loss time incidents (e.g., stuck pipe, downhole tool failure, and formation damage).
Once the data is integrated, effectively analyzed and presented in a meaningful way, there are benefits across the value chain, from exploration to transportation and export. Most relevant for regional NOCs, however, are the areas of: Drilling Optimization, Production Optimization (including reservoir modeling and management), and Executive Dashboards that can help decision makers better link the business with the realities in the field. Executive Dashboards, while conceptually not new, are advanced platforms that have the ability to give senior decision makers unparalleled insights. It is now possible to integrate the production data of every well in a portfolio, the capex projects, and the reservoir models to better understand the impacts of various decisions on the company's operations and business outlook. All this can be done on a single, easy-to-use dashboard, bringing the whole company to a CEO's iPad.
Many oil companies have invested in the needed technology. To maximize the benefits of digital oil fields, senior management must work to overcome the institutional barriers that keep the data locked away and prevent it from becoming useful information. It is important to remember that to do any of this, security is paramount. Specifically, it will be important to secure both the Operation and Information Technology environments. This means ensuring that best practices are being implemented at every stage of a project lifecycle, from design to operations and maintenance.
DR WALID FAYAD Executive Vice President Booz Allen Hamilton MENA


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Philosophy |
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Methods | Statistics | Clinical | Educational | Industrial | Professional items | World psychology |
Industrial & Organisational : Introduction : Personnel : Organizational psychology : Occupations: Work environment: Index : Outline
A non-commissioned officer (sometimes noncommissioned officer), also known as an NCO or Noncom, (US) is an enlisted member of an armed force who has been given authority by a commissioned officer. "Noncom" is the lesser-used term in many militaries since it may also refer to non-combatants. In the USA, the NCO corps includes all the grades of sergeant and, in some militaries, corporals and warrant officers. The naval equivalent includes some or all grades of petty officer, although not all navies class their petty officers as NCOs.
Template:Global The non-commissioned officer (NCO) corps (which in the USA, includes Navy and Coast Guard petty officers (PO)), is often referred to as "the backbone" of the armed services. NCOs are the primary and most visible leaders for the bulk of Service personnel – the enlisted corps. Additionally, NCOs are the primary military leaders responsible for executing the military organization's mission and for training military personnel so they are prepared to execute their missions. NCO training and education typically includes leadership and management as well as Service specific and combat training. Another critical role NCOs play is providing advice and guidance to the officer corps. This role is particularly important for junior officers, who begin their careers in a position of authority but lack practical experience, including commanders at all levels and flag officers (generals and admirals). Senior NCOs and Chief Petty Officers, with their wealth of leadership and mission training and experience are the primary link between the bulk of the enlisted personnel and the officers in any military organization.


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Detection methods predict differences in biology and survival in breast cancer patients
Translational oncology
The aim of this study was to measure the biological characteristics involved in tumorigenesis and the progression of breast cancer in symptomatic and screen-detected carcinomas to identify possible differences.
For this purpose, we evaluated clinical-pathological parameters and proliferative and apoptotic activities in a series of 130 symptomatic and 161 screen-detected tumors.
After adjustment for the smaller size of the screen-detected carcinomas compared with symptomatic cancers, those detected in the screening program presented longer disease-free survival (RR = 0.43, CI = 0.19-0.96) and had high estrogen and progesterone receptor concentrations more often than did symptomatic cancers (OR = 3.38, CI = 1.72-6.63 and OR = 3.44, CI = 1.94-6.10, respectively). Furthermore, the expression of bcl-2, a marker of good prognosis in breast cancer, was higher and HER2/neu expression was lower in screen-detected cancers than in symptomatic cancers (OR = 1.77, CI = 1.01-3.23 and OR = 0.64, CI = 0.40-0.98, respectively). However, when comparing prevalent
Incident carcinomas include a variety of screen-detected carcinomas that exhibit differences in biology and prognosis relative to prevalent carcinomas. The detection method is important and should be taken into account when making therapy decisions.
The widespread introduction of mammographic screening for breast cancer has led to a 20% reduction in breast cancer mortality
Therefore, screening enables the detection of breast cancers at an earlier stage of disease. It is now well documented that screen-detected cancers are generally smaller, of lower grade and less likely to have axillary lymph node involvement
A number of prognostic factors for symptomatic breast cancer have been identified. The important pathological features of prognostic significance are tumor size and the presence of lymph node metastases. In symptomatic breast cancer, the presence of lymph node metastases is generally considered to be the most important prognostic factor. In screen-detected cancers, however, the incidence of tumors with lymph node involvement is low because of earlier diagnosis and the smaller size of the tumor and is, therefore, of limited prognostic value. Fixing the size of the tumor (by comparing same-size tumors) reduces the lead-time bias. More important is the possible impact of length bias. It is theoretically possible to eliminate length bias by adjusting for the aggressiveness of tumors on the basis of a full biological description
At present, cancer detection based on mammography screening is not considered to be of significant importance when assessing the risk of breast cancer recurrence or in decision making concerning the need for adjuvant therapies in the diagnosis of early breast cancer. If cancerous tumors detected by mammography screening were associated with better outcomes than tumors of similar size detected by methods other than screening, women with a lower risk of recurrence might be subjected to adjuvant therapies. Recent studies have shown that screen detection remains an independent prognostic factor after adjusting for disease stage
This paper, therefore, examines whether a cancer detected by mammographic screening confers additional prognostic benefit to the patient over and above that expected by the improved stage shift. In addition, the pathologic features of breast cancer diagnosed in a first screening round (prevalent) were compared with those of incident cases on the basis that prevalent cancers have a potentially longer period over which to develop prior to detection than incident cancers, for which this period is theoretically limited by the screening interval.
Several studies have reported that tumors detected between mammography screening rounds (interval cancers) are similar to those found outside screening programs
Material and methods
Patients and samples
A nested case–control study was performed among woman who were histologically diagnosed with breast cancer and who had undergone surgical resection between 1996 and 2007. Thus, the study population consisted of 291 patients referred to the symptomatic (n = 130) and screening (n = 161) services of Costa del Sol Hospital. The symptomatic clinic was attended by patients who were referred with breast abnormalities, typically palpable lesions, by their primary care physicians. There were no differences in mean patient age between screen-detected and symptomatic carcinomas (56.33 ± 1.14 vs. 56.73 ± 1.18) (Table
In general, following an initial screen, women are invited to attend rescreening at intervals of two years, while annual screens are offered to individuals with a clinical indicator of increased breast cancer risk detected at screening or who had a first-degree relative with a history of breast cancer. This study was approved by the Costa del Sol Hospital ethics committee, and informed consent was obtained to supply tumor material for pathologic evaluation and immunohistochemical analyses.
Cancers diagnosed at the initial screening episode were designated as prevalent. Cancers diagnosed at a round subsequent to one or more screens in which cancer was not detected were classed as incident. All mammograms were reviewed to confirm incident tumors. In our series, there were 76 prevalent tumors, 65 incident tumors, and we also considered a third group, false negative mammograms, which included those tumors that were present in the first round but were not detected (n = 20).
Interval cancers, defined as cancers detected within 24 months after a negative mammogram but before the following invited screening, were excluded from this study. Furthermore, patients who received pre-operative adjuvant therapy were excluded from the study. In situ carcinomas were also excluded from the survival analysis.
In the survival studies, our primary endpoint was time to recurrence or breast cancer-specific death as measured from the time of diagnosis. Survival times of patients still alive or who died of other causes were censored as of the date of the last follow-up. Follow-up was conducted by the Hospital Tumor Registry and was achieved for 93.7% of patients with a median follow-up period of 71 months.
Finally, we considered treatment delay, which was defined as a delay of longer than one month between diagnosis and the first treatment.
All specimens were fixed in 10% neutral buffered formalin and embedded in paraffin. The following clinical and histopathological data were collected from all cases: patient age at diagnosis, differentiation degree, hormonal receptor status, tumor size, presence of regional (lymph node) metastases, tumor stage and patient survival. Pathological staging was performed according to the postsurgical International Union Against Cancer Tumor-Node-Metastasis classification. The histological typing and grading of the tumors was performed according to the World Health Organization classification. Two hundred and thirty cases were ductal adenocarcinomas and 61 tumors belonged to other histological subtypes.
HercepTest IHC assay
In this study, HER2/neu protein expression was evaluated using the HercepTest for Immunoenzymatic Staining at PPL according to the protocol described in the manufacturer's guide accompanying the kit. Tissue sections were deparaffinized in two 5-minute changes of xylene and were rehydrated using a gradient of alcohols culminating in distilled water. Subsequently, the slides were immersed in Dako Epitope Retrieval Solution (Dako, Copenhagen, Denmark, 0.01 mol/L citrate buffer; pH = 6) that had been preheated to 95°C; then, this solution was heated in a water bath at 95°C for a total of 40 minutes, followed by a 20-minute cool-down period at room temperature. The slides were incubated with the primary rabbit polyclonal antibody to the HER2/neu oncoprotein (as supplied prediluted in the HercepTest kit) on a Dako Autostainer for 30 minutes at room temperature. The antibody was localized by incubating the slides with the Dako Visualization Reagent (dextran polymer conjugated with horseradish peroxidase and goat anti-rabbit immunoglobulins) for 30 minutes using the Dako Autostainer. Diaminobenzidine (DAB) was used as the chromogen, and the sections were counterstained with hematoxylin. Positive controls were included in each staining run and consisted of freshly cut breast cancer cases known to express HER-2/neu and a control slide consisting of three pelleted, formalin-fixed, paraffin-embedded human breast cell lines with staining intensity scores of 0, 1+, and 3+ (supplied in the HercepTest kit). Negative controls consisted of substituting normal rabbit serum (Dako Negative Control Reagent) for the HER-2/neu primary antibody. Only membrane staining intensity and pattern were evaluated using the 0 to 3+ scale, as illustrated in the HercepTest kit scoring guidelines. As defined in the HercepTest kit guide, scores of 0 or 1+ were considered negative for HER2/neu overexpression, 2+ was considered weak positive, and 3+ was considered strong positive. To qualify for 2+ and 3+ scoring (i.e., positive), complete membrane staining of more than 10% of tumoral cells had to be observed.
We also used a modification of this scoring system that took into consideration the level of staining of nonneoplastic epithelium present on the same slide as the cancer. In this system, nonneoplastic epithelium was also graded on a 0 to 3+ scale using the same criteria used for the assessment of tumoral cell staining. Cases were considered HER2/neu positive only when the difference between the tumoral cell staining score and the nonneoplastic epithelial cell staining score was 2.
We studied tumor proliferation and the expression of hormone receptors and proteins related to the apoptotic process by detecting the expression of Ki67, HER2/neu, estrogen receptors, progesterone receptors and bcl-2 (Dako, Copenhagen, Denmark).
One representative block from each patient was sectioned at 5 μm and stained with the primary antibody. A standard, three-step technique using an avidin-biotin-complex/horseradish peroxidase (HRP) kit (Dako) was used as described previously
Protein expression was analyzed in 20 different fields of the tumors, and the reported values represent the means of the areas measured. Expression was scored as follows: negative if no staining was observed or if immunoreactivity was observed in less than 10% of the tumor cells and positive if more than 10% of the tumor cells showed staining with an intensity >1 (maximum value = 3). Samples were analyzed and scored blindly.
Scoring was performed by two independent observers, and discrepant results were discussed over a double-headed microscope.
In situ localization of apoptotic cells
To detect apoptotic cells, in situ labeling of the 3'-ends of the DNA fragments generated by apoptosis-associated endonucleases was performed using a commercial apoptosis detection kit (Roche Diagnostic, Germany). Briefly, deparaffinized sections were incubated with 20 μg/ml of proteinase K (Sigma Chemical Co. St. Louis, MO) for 15 min. Following rinsing in PBS, the slides were covered with terminal deoxynucleotidyl transferase plus a nucleotide mixture at a 1:35 dilution for 60 min at 37°C. Then, the slides were covered with an anti-fluorescein antibody conjugated with alkaline phosphatase. After substrate reaction, the stained cells were analyzed under a light microscope. Pretreatment of sections with DNase served as a positive control for the enzymatic procedures; omission of the enzyme served as a negative control.
Established morphological features used to identify apoptosis on H&E were also required in TUNEL-stained slides. Cells were defined as apoptotic if the entire nuclear area of the cell was positively labeled. Apoptotic bodies were defined as small, positively labeled globular bodies in the cytoplasm of the tumor cells that could be found either singularly or in groups.
One thousand cells were counted for each specimen. The number of positively stained cells was then divided by 1000 to estimate the percentage of apoptotic cells in each specimen. We used the mean level of apoptosis in our series (1%) (range 0.01-10.8%) as a cut-off.
Statistical analysis
Differences between the detection groups with regard to patient characteristics, including clinical, biological and histopathological variables, were analyzed via cross-tabulation (Fisher's exact test) for categorical variables and analysis of variance for continuous variables (natural log transformed when necessary). Survival curves were generated using the Kaplan-Meier method, and statistical testing was performed using the log-rank test. Multivariate analyses and HR calculations with 95% CIs were performed using the Cox proportional hazards model. All computations were executed using SPSS software (Chicago, IL). All P values are two-sided.
Symptomatic versus screen-detected carcinomas
Screen-detected patients had persistently smaller tumors (1.62 ± 0.14
After adjustment for the smaller size of the screen-detected primary tumors compared with control cancers, the differences between the two groups were maintained and related to axillary nodal metastases (OR = 0.25; CI = 0.13-0.47), percentage of in situ carcinomas (OR = 6.19, CI = 1.35-28.37) and estrogen and progesterone receptor expression (OR = 3.38, CI = 1.72-6.63; OR = 3.44, CI = 1.94-6.10, respectively). Furthermore, the expression of bcl-2 was higher (OR = 1.77, CI = 1.01-3.23) and that of HER2/neu was lower in screen-detected cancers compared with symptomatic ones (Table
When prevalent and incident tumors were separated and compared with symptomatic tumors (Tables
Prevalent versus incident screen-detected carcinomas
Comparison of prevalent versus incident screen-detected carcinomas (Table
In our series, we detected 20 cases with a previous false negative mammogram. In spite of the small number of such cases, we found statistically significant differences in the percentage of cells that expressed Ki67 antigens. Only 33% were positive in the group of false negative mammograms versus 63% for the true incident screen-detected carcinomas (OR = 0.29; CI = 0.08-0.98) (Table
Survival by method of detection
Screen-detected carcinomas had the longest survival period. This result was expected because the comparison of survival time would be affected by lead time and other biases. To minimize lead-time bias in the following analyses, we compared survival distributions by method of detection for patients whose breast cancers were the same size. After adjusting for tumor size, we found that screen-detected carcinomas presented a decreased percentage of recurrences and better disease-free survival. Thus, for tumors ≤ 2 cm, the percentage of recurrence was 30% for symptomatic tumors, while it was only 6% for screen-detected tumors (p < 0.05). When we selected tumors > 2 cm, the percentages were 39% and 14%, respectively (p < 0.05). Disease-free survival adjusted by tumor size relative risk (RR) was 0.33 (CI = 95%: 0.15-0.70).
When we introduced not only tumor stage but also biological characteristics into the multivariate analysis, the method of detection maintained its prognostic value (RR = 0.42; CI = 0.19-0.93).
Comparison of prevalent vs. incident carcinomas showed that survival was significantly shorter for incident cases (RR = 4.88, CI = 1.12-21, 19) (Figure
Figure 1
Disease-specific survival distribution in screen-detected carcinomas
Disease-specific survival distribution in screen-detected carcinomas. The cumulative survival of patients in the incident group (thick line) is significantly shorter than that of patients in the prevalent group (thin line).
No event was detected in the 20 cases of false negative mammograms.
We found the method of detection to be an important prognostic factor for breast cancer survival, even after adjusting for tumor characteristics.
Because lead time manifests itself as an earlier stage of disease, fixing the stage of disease reduces the magnitude of lead-time bias. Such an adjustment, however, has little or no effect on length bias. Cancers found via screening include a higher proportion of slowly growing tumors, some of which might never be found by other means; this observation represents an extreme form of length bias known as overdiagnosis bias. Some studies indicate that the disease prognosis may be predestined at the time of diagnosis, independent of the tumoral characteristics at diagnosis
The generally favorable outcomes of women with cancerous tumors detected by mammography screening compared with women whose tumors were found by other means might be explained not only by the smaller tumor size detected by screening but by the more favorable biological features of these tumors. In our series, cancerous tumors detected by screening were more often HER2/neu negative. In addition, bcl-2 and estrogen and progesterone receptors were found to be positive at a significantly higher rate in screen-detected tumors than in symptomatic tumors. Similar findings were reported by Crosier et al.
In the present study, breast carcinoma recurrence rates were significantly lower among screened patients compared with unscreened patients after adjusting for tumor size. Two previous studies
Interestingly, this study clearly shows that incident cancers are biologically different from prevalent ones. No previous studies have measured the expression of biological markers of prognosis in incident cancers. Incident cancers appeared to have worse prognosis than that of prevalent cancers based on the expression of biological marker. Additional tumor characteristics commonly associated with aggressive clinical behavior in breast cancer, such as positivity for Ki67 and HER2/neu, were associated with incident-detected cancers, which supports the hypothesis that incident cancers are biologically more aggressive than their prevalent screen-detected counterparts. Clearly, however, the size of breast cancers increases with time, as prevalent cancers were larger than incident cancers. The poorer outcomes for incident cancers may be associated with their biologic differences and more rapid tumor growth. In fact, these incident carcinomas were found after a "normal" mammogram, which suggests a faster growth rate for these tumors. It is known that indices of rapid growth are associated with breast cancer aggressiveness and poorer prognosis
It is possible that cancers diagnosed at the first screening round are subject to overdiagnosis and length bias; thus, first-round screening may have a lesser effect on breast cancer mortality. We also considered incident cancers separately from cancers found in the symptomatic group. Nevertheless, we found similar survival distributions for incident cancers and cancers detected in the symptomatic group.
In a previous work
We conclude that prevalent screen-detected breast cancer is associated with a favorable prognostic profile. Physicians should know that patients whose breast cancers are detected in the first round of screening have a higher probability of a better prognosis. Current treatment paradigms do not consider the method of tumor detection to be important when selecting systemic adjuvant therapies. We feel that the mode of breast cancer detection should be taken into account when determining individual patient management strategies. Studies with larger series of patients are needed to corroborate our findings and to identify new biological characteristics associated with the prognosis of screen-detected carcinomas.
ERs: Estrogen receptors; PRs: Progesterone receptors; TUNEL: Tdt-mediated dUTP Nick End Labeling; HR: Hazard Ratio; OR: Odds Ratio.
Competing interests
The authors declare that they have no competing financial interests.
Authors' contributions
MR: Conceived of the study, performed the statistical analysis, and drafted the manuscript. RF and IR: Evaluated immunohistochemical and apoptosis detection techniques. FMC: Acquisition and interpretation of data. MA and AB: Reviewed and classified the mammograms. TT and MJR: Performed the TUNEL technique. MLH and LD: Participated in immunohistochemical investigations. MMSV, MS and AR: Participated in the design of the study, interpretation of the results and drafting of the manuscript. All authors read and approved the final manuscript.
We thank Yolanda de la Torre for her excellent technical assistance. This work was partially supported by Fondo de Investigaciones Sanitarias (FIS 09/910, Spain).
Over-diagnosis in breast cancer screening
Surgical intervention in screen-detected patients versus symptomatic patients with breast cancer
Using autopsy series to estimate the disease "reservoir" for ductal carcinoma in situ of the breast: how much more breast cancer can we find?
Risk for distant recurrence of breast cancer detected by mammography screening or other methods
Pathologic findings from the breast cancer surveillance consortium: population-based outcomes in women undergoing biopsy after screening mammography
Role of detection method in predicting breast cancer survival: analysis of randomized screening trials
Screen-detected vs symptomatic breast cancer: is improved survival due to stage migration alone?
Molecular characteristics of screen-detected vs symptomatic breast cancers and their impact on survival
Screening interval breast cancers: mammographic features and prognosis factors
Survival in interval breast cancer in the DOM screening programme
Major histocompatibility complex status in breast carcinogenesis and relationship to apoptosis
Stable portrait of breast tumours during progression: data from biology, pathology and genetics
A progression puzzle
Prognostic factors for recurrence and survival in human breast cancer
Clinical practice guidelines for the use of tumour markers in breast and colorectal cancers
Apoptosis in breast cancer as related to histopathological characteristics and prognosis
bcl-2 expression and apoptosis in primary and metastatic breast carcinomas
Bcl2 immunoreactivity in breast carcinoma correlates with hormone receptor positivity
Bcl-2 is a prognostic marker in breast cancer independently of the Nottingham Prognostic Index
Meta-analysis confirms BCL2 is an independent prognostic marker in breast cancer
DNA flow cytometric analysis indicates that many breast cancers detected in the first round of mammographic screening have a low malignant potential
Prognostic value of morphometry and DNA flow-cytometry features of invasive breast cancers detected by population screening: comparison with control group of hospital patients
Differences in Ki67 and c-erbB2 expression between screen-detected and true interval breast cancers
Prognosis, treatment, and recurrence of breast cancer for women attending or not attending the Screening Mammography Program of British Columbia
Outcome of radiotherapy after breast conserving surgery in screen detected breast cancers
Ki-67 immunostaining in human breast tumours and its relationship to prognosis
Ploidy, proliferative activity and prognosis. DNA flow cytometry of solid tumours
Effects of emergency admission and delays on prognosis in patients with breast carcinoma
Pre-publication history
The pre-publication history for this paper can be accessed here:


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The Health Select Committee is investigating people's views.
Parliament's Health Select Committee is conducting an investigation into ending one's life (suicide) in New Zealand. As part of this investigation, they are hearing what people's attitudes are about the legalisation of assisted suicide: whether it should become legal to encourage or help someone else die by suicide. More information on the investigation here.
Are you informed about the issue?
Did you know that people request assisted suicide mainly for psychological and spiritual reasons, even if they are terminally ill? Did you know that when people receive treatment for depression, their wish to die almost always disappears? Watch a short video here
Did you know, assisted suicide is being proposed not only for the terminally ill, but for almost any New Zealander over 18? (We're not talking about switching off life support, do-not-resuscitate requests, refusing or withdrawing futile treatment. We're not talking about a doctor giving a person pain relief to make them comfortable. Read more here.)
Here's a short video on why we don't treat humans the way we treat animals.
Be informed so you can have your say.


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Monday, June 13, 2011
Deja Vu
At the hospital today, I saw a patient who looked so much like my father -- same bushy eyebrows, same eyes, same hair -- that I almost started crying in the room (and did cry after I left: I hid in a back storeroom for a few minutes and sniffled). These days, I'm pretty good at comforting myself by remembering that I carry my parents inside me, but the shock of seeing those familiar features made me realize, quite painfully for a few minutes, how much I miss having them walking around in the world.
The department was exceptionally busy today. In two hours, I offered chaplaincy services to seventy-four people, and that was just patients, friends and relatives within the ED proper (lots of large family groups today, which always drives up the census). I visited the internal waiting room, but never even got out to the main waiting room. This meant that I didn't have much time to be sad, which was probably good.
A later visit, though, pushed the same buttons: a young woman sitting at her elderly father's bedside, weeping in worry and exhaustion. I gave her a hug and told her that I know how hard it is to be in that position. She seemed to appreciate the empathy.
Do I really want to be sitting next to my father's hospital bed again? Well, no. But I miss walking into any old room and finding him there, eyes twinkling.
Another volunteer chaplain's working from five to nine tonight. If his evening's anything like my afternoon, he'll have a very busy shift!
Posted by Susan Palwick at 7:28 PM
Labels: chaplaincy, family, hospital, loss
2 comments:
That must have been quite a shock to you. I remember when my daughters first child was born. My husband and I were down in the lobby waiting for her and my husband just went rigid. Look,look he whispered to me. And right there in the hospital my late father walked right across the lobby, turned and looked at us and walked out. My throat shut up tight and I was ice cold. I swear, that man, every inch of him looked like my dad. He even walked like my dad. It took a while to get over it and even now I get goosebumps thinking of it. Sometimes I wonder Susan, sometimes I wonder.ReplyDelete
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Claire Messud's new novel, The Burning Girl, feels somehow different from anything she's done before...
Condition: Like New
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Fear and Loathing at Rolling Stone showcases the evolution of a writer and a magazine. Jann S. Wenner, Hunter Thompson's editor and friend for nearly thirty-five years, has selected the pieces — including many never collected before — to show Hunter's Rolling Stone writing, when taken as a whole, as an extended, allusive autobiography of the writer himself pursuing his lifelong obsession, the king-hell story of them all: The Death of the American Dream.
From Hunter's first piece for Rolling Stone — the story of his infamous run for sheriff of Aspen in 1970 on the Freak Party platform — to his last piece on the Kerry/Bush showdown in 2004, with plenty of Nixon, Watergate, Vietnam, Muhammad Ali, and Bill Clinton woven in along the way, Fear and Loathing at Rolling Stone presents forty-two examples of the best of Hunters work edited anew, along with never-before-seen selections from the correspondence between Wenner and Thompson. The result is a vital inside glimpse of the rollicking spectacle of a writer at his peak, delivering the work of his career to the editor of the magazine that became his literary home.
Jann S. Wenner, the outlaw journalists friend and editor for nearly thirty-five years, has assembled articles that begin with Thompson's infamous run for sheriff of Aspen on the Freak Party ticket in 1970 and end with his final piece on the Bush-Kerry showdown of 2004. In between is Thompson's remarkable coverage of the 1972 presidential campaign — a miracle of journalism under pressure — and plenty of attention paid to Richard Nixon, his bête noire; encounters with Muhammad Ali, Bill Clinton, and the Super Bowl; and a lengthy excerpt from his acknowledged masterpiece, Fear and Loathing in Las Vegas.
Woven throughout is selected correspondence between Wenner and Thompson, most of it never before published. It traces the evolution of a personal and professional relationship that helped redefine modern American journalism, and also presents Thompson through a new prism as he pursued his lifelong obsession: The life and death of the American Dream.
Hunter S. Thompson died February 2005.


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Vall De Font is a Holiday Villa in Mancor De La Vall, Mallorca with a Private Swimming Pool
Ref: 1441
4 Bedroom, 3 Bathroom Villa with Mountain View and a Private Swimming Pool , Air Conditioning, Satellite TV, near Golf, Sleeps a maximum of 8 people.
This four bedroom villa sits nestled it the foot of the UNESCO listed Tramuntana mountain Range providing a perfect platform for adventuring off in any direction on the island.
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it has four bedrooms, three bathrooms, fully fitted kitchen and dining area. There is an alfresco dining area and seating area on the terrace overlooking the pretty gardens and pool, whilst still enjoying the views of the nearby village.
There are a number of sun terraces and quiet corners in which to relax in peace. Mancor de la Vall is only 30 mins from Palma Airport and 30 mins from central Palma.
The famous tourist hotspots such as Soller, Deia and Lluc in the mountains towards the North/North East.
*Please note that a security deposit of 150 must be provided when renting this property.


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Dodge Viper Suspension Under NHSTA Probe
You may have heard that the Dodge Viper is a car that wants to kill you, but in at least two cases that might actually be true.
That's because the National Highway Traffic Safety Administration (NHTSA) is currently investigating model year 2005 and 2006 Dodge Vipers because of two complaints that the rear suspension knuckle separated, which caused the drivers to lose control and crash.
One of the complaints says while driving approximately 50 mph, the knuckle assembly failed and the vehicle stopped suddenly. The driver crashed into a concrete divider.
NHTSA hasn't issued a recall so far, but one could be issued.
Another complaint said a man was driving his 2006 Dodge Viper when he lost traction to the left side and started to slide. The car went airborne and crashed into some woods nearby. The driver suffered lower back injuries and a mechanic determined that a steering knuckle separated from the right rear wheel.
Discuss this story at ViperAlley.com


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CyanogenMod 10 for Galaxy S2 Skyrocket, Android 4.1.1 Jelly Bean Based ROM
After the Galaxy S2 I9100 and Galaxy S2 I9100G, the CyanogenMod 10 has been released for the Galaxy S2 Skyrocket. The CyanogenMod 10 (CM10) is based on Android 4.1.1 Jelly Bean, the ROM brings a smooth performance and gives you full stock Jelly Bean experience on your Android phone, thanks to XDA developer member sk8erwitskil.
The ROM is still in development and has bugs, it's not full sable for daily use, you may face bugs in camera and in-call echo. If you really want to try CM10, follow below guide to install CM10 on your AT&T Galaxy S2 Skyrocket.
ClockworkMod recovery is installed on your device, make a backup of your device data such as SMS, internet setting, contacts music files etc because the below procedure may wipe data, you can sync your contacts with Gmail account and for messages use SMS apps, lastly use file expert app to backup apps.
DISCLAIMER: Please proceed the below guide at your own risk, Android Egis will not be held responsible if your device lost data or get damaged following this guide.
Step #1: Download the latest version of ROM from here [XDA LINK] and Google Apps.
Step #2: Transfer the downloaded file to the internal SD card of device.
Step #3: Turn the device off.
Step #4: Reboot the device into recovery mode by holding down Volume up, volume down and power buttons until device turns on.
Step #5: In recovery mode, create a nandroid backup of your current ROM, it's important because if anything not work out that you expect from this ROM, you'll be able to easily revert back to your current state. To create backup select "Backup and Restore", and then select "Backup" again.
Step #6: Perform full wipe, first select the wipe data/factory reset, and confirm on the next screen then select wipe cache and confirm on the next screen. Lastly also wipe delvik cache from advance menu,
Step #7: Select "Install Zip from SD Card" then "Choose Zip from SD Card" and locate the downloaded ROM .zip file that you've transferred in above step and confirm installation. Wait till installation complete.
Step #8: Once again, repeat the last step to install Google Apps .zip file.
Step #9: Once the installation is completed, select "Go Back" after that select "Reboot System Now."
That's it, enjoy CyanogenMod 10 Jelly Bean on AT&T Galaxy S2 Skyrocket. Do comment below for queries, to go back, simply put device in recovery and restore backup, you've taken. You can also visit the original thread of XDA link given in step 1.


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January 23, 2011 by staff
GEICO, Once identified by Buffett at the head of Berkshire potential investment in an emergency, Simpson retired after over 31 years of stock picking for his "Geico Corp"auto-insurance subsidiary. Buffett in Berkshire's annual letter to shareholders for the year 2004, devoted a section to Simpson entitled "Portrait of a disciplined investor," says his choices have produced an average annual return of 20 percent since 1980, compared to 14 percent for the Standard & Poor's 500 Index.
"He just hit the ball cap of the year after year," said Jack Byrne, the former president "Geico"qui hired Simpson with the participation of Buffett in 1979." I asked Lou for 20 years if he would take a separate account with me. "
Simpson said he planned to stay "Geico"pour a year or two, only to change his mind after buying a home in Naples with Querrey last January with 13 million, a price described in the documents public properties to the Florida Collier County. Once the couple decided to make Florida their primary residence, Simpson chose to end his career in asset management, a choice that proved short-lived.
As CEO of "capital operations"Geico, Simpson has received some of the stock returns of the insurer that was above average for the S & P 500 over periods of three years, according to Mr. Byrne. Buffett has referred to the 2006 Convention in his letter to Berkshire shareholders.
"Under this agreement, he won large amounts," Buffett wrote. "Lou, however, may have long since left to manage much more money at more favorable terms."
Duck is back in fourth place before JGR / Yamaha Justin Brayton Muscle Milk, while "GEICO"motorisés Honda Kevin Windham finished sixth ahead Motorsports Honda Chad Reed TwoTwo, which fell on the first round after hitting a block of tufa who was hit on the runway.
Rockstar Makita Suzuki Brett Metcalfe finished eighth, with Red Bull KTM Andrew Short in the ninth and Kyle Chisholm Yamaha Motorcycle Concept at the 10th.
Cole Seely topped with a wild start in the Lites main event to lead to a group that included Josh Hansen and Eli Tomac. Hansen won the second round and dropped outside the top 10, the delivery of the runner-up slot in a hard-charging Tomac. In the meantime, Hansen Monster Energy / Pro Circuit / Kawasaki teammate Broc Tickle and Rockstar Energy Suzuki's Ryan Morais began a battle on the third, which was to last the rest of the race.
Finishing three seconds back in second place was Tomac, who kept his "GEICO"Honda just far enough from the battle for third to stay out of danger. Meanwhile, Morais made a pass on the final lap to steal Tickle place on the podium.
Hanson collected some championship points on his way to fifth by the end of the race, topping the Red Bull KTM Roczen Ken, who was also forced to fight his way back after going out in the first round.
Ryan Marmont KTM Also finished seventh in front of Honda rider James Decotis and Shred Stix DNA / Yamaha teammates Nick Paluzzi and Kyle Cunningham.
Please feel free to send if you have any questions regarding this post , you can contact on
Disclaimer: The views expressed on this site are that of the authors and not necessarily that of U.S.S.POST.


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Golf tournament to be held to raise money for charity
April 29, 2013
The Centennial Rotary Club of Greeley is calling for entrants to its 24th annual golf tournament to raise funds for local Habitat for Humanity, Meals on Wheels and Rotary Service projects.
The event is schedule for May 10 at the Boomerang Links golf course in Greeley. Participants can begin checking in at 7:30 a.m., and the tournament begins at 9 a.m. A lunch and awards ceremony is scheduled for after the tournament.
Individual players pay $120, and corporate sponsors pay $480 per foursome. The fee includes range balls, green fees, cart rental and lunch. Corporate fees also include recognition on the course and in the tournament program.
Entry forms are due May 1. Players may send entry forms and checks to the Centennial Rotary Club, P.O. Box 337436 Greeley, CO 80633. Contact Bruce Bode, (970) 590-4333, or Glen Droegemeuller, (970) 304-0362, with questions.
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When Muslims and Christians Study Vedas
By Swami Abayananda Tirtha
Imagine a young man claiming to be an ophthalmologist, and he seeks to surgically operate your eyes. As you wonder about his qualifications, he beams, "I have studied the books on my own and am confident of performing an operation." Will you volunteer to be operated by such a 'knowledgeable' eye surgeon? A surgeon has to study and practice under a bonafide surgeon before qualifying himself. If all the surgical tools are kept on the table, will a cataract patient, even though well versed in the subject, operate himself?
There is havoc in spiritual circles when people study Vedas without the guidance of a spiritual teacher (guru), who preaches and lives by the Vedic teachings. Self study and arm chair commentary maybe permissible for subjects such as history, politics etc but Vedic wisdom are transformational in their potency, and require careful tutelage and practice of spiritual practices (sadhana). Just as an untrained surgeon causes more harm than good, an untrained Vedic commentator confuses people and takes them further away from enlightenment. This understanding assumes importance in the wake of claims by Muslim, Christian and Buddhist preachers that Hinduism is backward. These self-proclaimed saviors of mankind quote Vedic texts to prove the superiority of their own respective faith, and establish their own myopic view of God and Truth.The Svetasvatara Upanishad (6.23), Srimad Bhagavatam (6.3.19), Bhagavad Gita (4.34), besides many other Vedic scriptures, emphasize on the need to study Vedas under a practicing Vedic teacher, and not from a commentator with an ulterior motive. Will a Muslim accept Quran passages cited by Salman Rushdie, Taslima Nasreen or Dr Ali Sina (www.faithfreedom.org). A honest Muslim or Christian would be offended by citations offered by the apostates of their respective religious faith. Similarly Vedic scriptures are not the property of one's own whims and fancies. Unfortunately today, anybody can comment and portray Hindu scriptures in poor light without being admonished for the same. Little wonder, when M.F.Hussain paints Hindu goddesses in nude, Indian media appreciates his creative art work, while vocally criticizing the caricature of Muhammad by a Dutch artist.
When a person studies the Vedas sincerely under a guru, the effects are revolutionary. Dara Sukoh, the successor to the Muslim Emperor Saha Jahan, undertook this adventure. In 1640, Dara Sukoh visited Kashmir and learnt Upanishads from the learned pundits. He also accompanied his teachers to Benares and Delhi and wrote 'Majma-ul-Bharain', 'the mingling of the two seas', in an attempt to reconcile Islam and Hinduism. In 1657, he completed his translation of fifty Upanishads into Persian. He called it the 'Sirr-e-Akbar', 'the greatest mystery'. In the introduction of this book, he states that Qur'an's 'Kitab-al-Maknun' or the 'hidden book', is none other than Upanishads(Max Muller, in the introduction to 'The Upanishads'). He thus established that the Vedic scriptures are profound in their depth and unsurpassed in history by any other religious or spiritual text. However this had infuriated the orthodox Muslims and his younger brother Aurangazeb had him executed under the Islamic Sharia law for being an apostate. The Islamic law of jurisprudence awards death penalty on a kafir, anyone who rejects the Islamic faith.
A religious system that is insecure pronounces death and violence as a tool to invoke fear in the hearts of the followers, lest they leave the religion. If a member of the underworld gang seeks to reform and desires to lead a civilized life, his gang members wouldn't let him go, for he 'knows too much'. Similarly, insecure religious systems pronounce death on those who reject their religion, for they may call upon the other followers to experience a better path.
Interestingly Vedic literatures encourage assimilation of wisdom from all sources. The Rig Veda exhorts, "Let noble thoughts come to us from all sides." Ill informed people may condemn and brandish the Vedic culture but its here to stay. Having survived over the last five thousand years, the world's oldest and strongest spiritual culture calls for peace and love.
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Author: Jennifer Forman Orth
Invading your brain since 2002.
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Knotweedy Originally uploaded by urtica.
Japanese knotweed stems with fruits still intact, mid-January. Each fruit is a papery, winged achene containing a single seed. By the spring many of the achenes still attached to the plant will be empty, eaten by birds or more likely knocked away by the wind.
A lot of people are under the mistaken impression that Japanese knotweed doesn't spread by seed. While it has been quite successful at invading new sites via pieces of rhizome or stem, its seed is viable and is actually easy to germinate (don't try this at home folks :-)).
Labels: Flickr, Japanese knotweed, photoblogging, photography, plants
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The stuff pack is still under devolovment. the stuff pack will introduces a lot of Demi-styled items and clothing. It's the first pack for me, so I'm very excited!
The pack is 60% done :) There is an "arrival" trailer, and the full trailer will be here this week or later. There is problem with my Sims 3 game, so screenshots won't be here for a while. There is some screenshots in the pack's page.
About me:
My name is Bella (It's Ariel because I logged in from my brother facebook). I'm 17 years old, from Israel. I love Demi for about 2 years, I just love everything about her. I really love the Sims, I started to play with The Sims 2, and now with The Sims 3. I have all the expansion packs and 4 stuff packs (now you can see why my game is not working :/).


text: People burn fireworks to celebrate the Chinese New Year. In Hong Kong traditional ropes of red firecrackers were banned after the riots of 1967 - at least that was the excuse. Firecrackers and high-density urban areas don't go together. Are dead and maimed children worth the rituals of "tradition" ? Instead, Hong Kong developed a new heritage - massive public fireworks displays and laser lights over the harbour. Everyone joins in and celebtates together.


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You will not find a supplier anywhere for this product at this time. They are comming direct from nintendo to the retailers. If you want them you have to get them from nintendo and you had best have alot of money. :D
Jimmy ill challenge you on your post here, if you like...ill prove im getting 20+pcs a wk of such products ! but i want something in return tho..is that a deal?
LOL.Im glad ive perked you up jimmy
Terms free add on ya site for a year!
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Influx Gleam SoHo Operator Armchair Mesh Seat Black
Frequently Bought Together
Other Mesh Office Chairs
Mesh Back Office Chair With Arms & Chrome Base Bla
Influx Mesh Task Chair With Arms Black
Influx Gleam SoHo Operator Armchair Mesh Seat Blac
Ergonomic Mesh Task Chair With Lumbar Support & Ad
Influx Amaze Mesh Task Chair With Headrest Black
Ergonomic Mesh Task Chair With Lumbar Support & Ad
Arista Fusion High Back Mesh Chair With Lock and T
T50 Task Chair - Black
Ergonomic Mesh Task Chair With Headrest Lumbar Sup
Influx All Mesh Task Chair Armchair Black
Executive High Back Mesh OP Office Chair
Ergonomic Mesh Task Chair With Lumbar Support & Ad
Influx Amaze Task Chair Mesh Black
Adroit Montgomery Heavy Duty Armchair Mesh Back Bl
LightUp Modern Design Ergonomic Mesh Office Chair
Flash Mesh Office Chair With Tension Control Adjus
Mesh Office Chair With Adjustable Back Blue Profil
Jemini Medium Mesh Back Task Chair Black KF73602
Grantham Mesh Operator Chair
Ergonomic Mesh Task Chair With Lumbar Support & Ad
Ergonomic Mesh Task Chair Adjustable Arms Black/Gr
Xenon Swivel Ergonomic Mesh Back Task Chair Red
Product Specification
- Product Code
- 433458
- Weight
- 14.50 kg
- Pack Size
- 1
- Pack Dimensions
- 640x285x590 mm
- Manufacturer Ref
- 11027-03
- Barcode
- 5018206269713
- Type
- Standard Chairs
- Height
- Medium Back
- Colour Finish
- Black
- Material
- Mesh
- Arms
- With Arms
Product Details
- Influx Gleam SoHo Operator Armchair Mesh Seat Black
The Influx Gleam SoHo Mesh Chair is part of a selection of Influx Amaze modern mesh office chairs. This mesh back chair is finished in black and has modern slim-line look . This office chair offers the user the highest comfort for eight hours a day, 5 days a week. The mesh backrest provides good airflow and allows your back to breathe while delivering firm support for maintaining correct posture. This chair comes complete with fixed arms. The perfect complement to your workstation
Recommended Usage
|Chair Usage
Good quality all round chair, ideal for secretarial, word processing, clerical, professional and accountancy jobs.
|Weight Capacity
Suitable for up to 18 stone or 114kg
|Height Adjustable
Users can adjust height of seat to maximise support for legs.
Seat height can be adjusted from 410mm to 510mm
|Fixed Arms
Chair supplied complete with fixed arms.
The Influx Gleam SoHo Mesh Chair meets BS7176 Medium Hazard standard and comes with 2 years warranty.
Material & Colour
Seat WxD: 470mm x 480mm
Back Rest Height is 430mm including headrest (measurement is the chair back only and excludes chair base, seat etc,)
Product Reviews Ireland
Average rating:
2 Most useful product reviews (see all reviews):


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Sensational Resham Work Mouni Roy Party Wear Salwar Kameez
You look so charming wearing this attire. Make the heads turn the moment you costume up in this cream color faux georgette Mouni Roy party wear salwar kameez. The ethnic lace work, resham and stones work for the attire adds a sign of magnificence statement to your look. Comes with a matching bottom and dupatta.
Product Code: 31929
Product will dispatch in 10 - 12 Days
Stitching (if required) will take 4 to 5 days extra.
Shipping Charges: $13.95 / All India Free Shipping
Free Shipping On Orders Above USD 199
Best Lowest Price Guarantee
Price Match Promise
100% Original Products
Price Match Promise
100% Original Products
Free Shipping On Orders Above $199 USD
Shipping By DHL Express & Fedex Express
Quick & Secure Delivery
Shipping By DHL Express & Fedex Express
Quick & Secure Delivery
100% Premium Quality
100% Branded Products
We Do Sell Only Original
100% Branded Products
We Do Sell Only Original
Style: Trendy Suit
Shipping Time: 10 - 12 Days
Fabric: Faux Georgette
Color: Cream
Celebrity: N/A
Catalogue No.: 3298
- The first wash of the garment should always be Dry-Cleaned.
- Slight variation in fabric, color and work is possible.
- Border of the suits may be vary at back side.
- Jewellery shown in the Image is not a part of the product.
- Front and back neck deep depends on the design and pattern on the Kameez.
- Maximum possible bust size is 44 inches.
- Kurta length can be made between 38 to 54 inches.
- Kurta (Kameez) length will be customized as per products fabrics availability.
- Customized Stitching process will take 4 to 5 days extra.
- All measurement should be in Inches only.


text: Handcrafted by experts using only the finest of materials, the draught stopper is a superb addition to your home. With it's simplistic design and practicality this draught stopper will look marvelous complimenting our fantastic range of French furniture and French interiors. So add some style and elegance in your wonderful home today.


text: A beautiful traditional music released by Alireza Ghorbani with a co-operation of famous Iranian musician Sir Homayoun Khorram. The name of this fantastic music is "Rosvaye Zamaneh" and it's one of the best jobs of Alireza Ghorbani on his professional job. I'll invite you listen this brilliant music and hope you be happy after hearing this.


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New signing Isaac Hayden had a decent season last term on loan at Hull City and he helped them to get promoted – and since he joined Newcastle yesterday he has talked about last season being a very good season for him.
It was a good experience for Geordie manager Steve Bruce too, getting Hull promoted at the first attempt after they were relegated from the Premier League in May of 2015.
Isaac Hayden while on loan at Hull City
But Steve wasn't able to sign Isaac on a permanent deal, which he initially wanted to do last January.
The Hull manager was again after the 21 year-old holding midfielder this summer, but Newcastle and Rafa Benitez beat the Yorkshire club to the player's signature.
Isaac has said since he joined the Magpies that Rafa went down to London in mid-June and talk to the youngster for a full two hours.
After that – when they talked about Isaac's strengths and weaknesses and about football tactics – Isaac said he knew he only wanted to play for Rafa Benitez – and Newcastle.
This is what Steve Bruce told the Hull Daily Mail on January 18th of this year, after Hull had just hammered Charlton 6-0 at home and Isaac had scored his very first senior goal of his career:
"I've already been onto Arsenal because I'd love to make it permanent if I could,"
"I'd make it permanent tomorrow if that was possible. I desperately want to hang on to him."
"In an ideal world he'd want to be playing every week but he's started last weekend.
"He's a very good young player, who's progressing all the time."
"He's got his goal and he did very well. He's energetic and full of beans and he'll remember his first goal."
"I wanted to freshen us up in midfield and he was one who took his chance well. It was very good to see.
Rafa has so far signed five good players in about 12 days and we are hoping that next one through the door will be Blackburn's Grant Hanley within the next day or two.
Comments welcome.


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The Ad Fab two some are back for their first ever movie, and they're going toe to toe with The Rock at the box office.
Absolutely Fabulous the Movie
Edina and Patsy are pretty much the same as you remember, until they appear to kill off Kate Moss and have to go on the run to the French Riveria. Jennifer Saunders returns to the show she first created back in 1992, and Joanna Lumley is also on board for some high fashion hijinks.
Central Intelligence
The Rock used to be the unpopular kid in high school but now he's The Rock and he's reteaming with an old friend played by Kevin Hart to get into some serious trouble. Expect action and laughs as well as some very fast talking from the hyperactive Hart.
The Colony
This period thriller set in Chile in the 1970s deals with a young couple who get caught up in the affairs of General Pinochet. Emma Watson is forced to infiltrate the mysterious and deadly Colonia Dignidad to track down her lost boyfriend. Based on a true story.


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The Irish Exodus.
Published: May 15, 1860
The Irish emigration to this country which it was supposed, a year or two ago, would abate under the influence of great prosperity at home, has again set in with such violence that the English Press begins to prophesy the total transfer, at no distant period, of the Celtic population to America, and the filling up of their ancient seats by a new "plantation" of Englishmen and Scotchmen. The London Times contemplates this result with great apparent satisfaction, and seeks to reconcile the departing exiles to their change of residence by the comforting assurance that America is the real home of their race. Considering what the condition of Ireland now is, as compared with what it was forty years ago, and considering, especially, the enormous advances it has made in material prosperity within the last ten years, the phenomenon which we are now witnessing, of this emigration of an entire people, famous for their strong local attachments, is one of the most remarkable in history. It is rendered all the more remarkable too, by the fact that, no matter how much political considerations may have done to set the stream flowing towards our shores fifty years ago, they have had little or nothing to do with the fullness and rapidity which mark it in our own day. We can no longer learn from stump orators or debating societies the real reason for the Irish peasant's quitting his home in the "old country." The political condition of the Irish Catholic has for some years ceased to be a whit worse than that of the English Protestant Dissenter. In some respects it is even better. He has supplied to him by the Government a good system of secular education for his children -- a luxury which the Methodist and Congregational masses of Great Britain are not likely to enjoy for many a day; and of late he has enjoyed an amount of Government patronage which the English Dissenter need not hope for. A large proportion of the Irish Judges are Catholics, as well as the representatives of the present Government at the Bar. The best legal appointments in the colonies, still in the gift of the Crown, have been for the last ten years bestowed on Irishmen. Irish Catholics muster largely on the rolls of the local magistracy. They have begun to muster largely at the mess tables of the army. They fill the corporations of the cities almost exclusively; they are represented in the House of Commons by a compact and clamorous body, which knows how to make itself formidable to the strongest ministry that now-a-days ever finds itself in office. In fact, the tendency of all the liberal Administrations of England for many years past has been to visit on the Irish Protestants those measures of proscription from which their Catholic countrymen once suffered. It is well known in Dublin that with Whigs, or Peelites, or Radicals in office in Downing-street, a Protestant's chances of a "berth" or of promotion are almost as small as a Catholic's used to be forty years ago. The tremendous power which the Emancipation Act raised into existence -- the power of a turbulent and ill-educated clergy over hosts of ignorant and fanatical voters -- is a power which has to be conciliated at any cost. Even the "Protestant Conservatives," under the "chivalrous" Earl of DERBY, have succumbed to its might. At the general election which preceded the peace of Villafranca, the combination between the priests and the Tories, for the purpose of bringing about a coalition with Austria against France, for the protection of the Pope and the concordat, was made manifest at every hustings from the Giant's Causeway to Cape Clear. In short, as far as the relations of the Irish Catholic with the Government are concerned, he has only the Church establishment to complain of; and this burden, as we have said, is one which presses with equal weight on the shoulders of the English Dissenter. In all other respects he stands on the same footing as any other British subject. Habeas corpus and trial by jury are now his birthright; and as to the liberty of the Press, the Dublin Nation is astounding evidence that the Irish Press is the freest Press in the world. In no other country would a newspaper be allowed, as this is, to preach insurrection every week, and to make common cause, on every possible opportunity, with the bitterest foreign enemies of the Powers that be, without either receiving any notice from the law or the mob.
In short, Ireland is now furnishing on a great scale a striking proof of the worthlessness of political liberty, unless accompanied with security for property. The Irishman of to-day is amongst the freest men on earth, as far as laws can make him so. But the land laws are such that he is never sure either of continuing in his home, or of reaping the fruits of the labor he expends on his land. The vast mass of the tenantry are holders at the will of the landlord, and the barbarous relic of feudalism, which enables the owner of land to appropriate every improvement made on the soil by the toil of others, is maintained by the Courts in full vigor. The landlords will not grant leases, partly because it is not necessary in order to secure a high rent, and partly because they make the lessee politically independent on election day. More than this, the longest lease, even where leases are granted, comes to an end at last, and the man who has expended the best years of his life upon his farm, may find himself turned adrift with his family without a cent of compensation for the improvements of many years. To this evil -- the worst of the "evils of Ireland" -- the Incumbered Estates act has brought no remedy. The agitation for a "Tenant-Right bill" has been carried on for many years, and been regularly met by the victorious opposition of the landlords. Nor is the prospect of success at this moment any greater than ever. Under these circumstances, it is not surprising that the faces of the mass of the population should still be turned westward. Large numbers of them came here when Ireland was a worse place to live in than it is now. The remainder are following, because the greatest element of prosperity is still wanting. They seek a country in which the poorest is sure of being able to bequeath to his children the product of his toil and thrift, and in which his children have the highest prizes of life within as easy reach, as those of the wealthiest and best born. There is something unquestionably touching in the final disappearance of a people which has preserved its vitality, its hopes and hates through a struggle of six centuries. But any sentimental regret we may feel at seeing the "last of the Irish" absorbed into the turbid mass of American Democracy, is modified by the reflection that whatever of good such a long oppression has left in them must of necessity be more fruitful here than at home; that though the nation disappears, the individual men exchange the sober certainty of all that makes life valuable, for the sickly sorrows and fantastic hopes of a nation which owes its poorest privileges to the pity of its conquerors.


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This round jar is melon shaped jar is handmade and hand-painted in the Tuscan town of Montelupo. It is illustrated with pomegranates and grapes in a soft pastel spectrum. Generously filled with one-pound and two-ounces of individually-wrapped biscotti, macaroons and chocolate biscotti.
Height: 11"
Diameter: 9"
Net Wt. 1 lb. 2 oz.


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A Meboid is a small amoeba-like creature that poses little threat to Samus. Despite the fact that it may seem so, it is not related in any way to the Metroids. It barely moves, and stays close to where it appears. These creatures may have made a return in Metroid Fusion as infected and/or X-mimicked variants called Yamebas.
"This is an amoeba-like creature. They just move back and forth."
- It is unknown if the Meboid species was infected by the X Parasites, as Samus never encountered any Meboid-X in Fusion.


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Author Archives: manan
The Band Will Eventually Be Disbanded
A separate health band won't be a category soon, Microsoft won't get partners to license the Band software. It's game over for the Microsoft Band. Continue reading
Introducing The Netflix and Chill Entertainment Control Center
Your 1 page netflix and chill control panel that opens romantic Spotify playlists and Netflix movies, allows you to call Uber and order food. Continue reading
Journalism In India Is Failing Us
Every now and then I come across an article or video from a legitimate news organization that only makes me feel sad about the state of journalism in the nation. As a citizen I want my news source to inform … Continue reading
Microsoft Band: The Polished Prototype
Microsoft Band, the good, the bad, and the ugly. Continue reading
3 Things Cortana Can Do Better
Cortana seems like a winner, I wish it actually made me feel like I had an assistant. Continue reading
Xbox LIVE Gold: A Waste of Money
Google Chromecast is more value for money than Microsoft's Xbox LIVE Gold subscription. Continue reading
The Xbox Mobile
Microsoft has an Xbox mobile device that maps the real Xbox controller on the touch screen. Continue reading
Android Is The New Windows
Touching several topics such as why iOS is mediocre, WP8 though better is a bad choice, why Nokia was wrong, and why Android is winning converts. Continue reading
Microsoft's Continued State of Mobile Oblivion
While Apple & Google perfect the phones of the future, MSFT doesn't know its OS's future. Continue reading


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Richard is a great people person making him a pleasure to work with, whilst focussing on key objectives he has a way getting the most out of people by outlining the challenge, listening to ideas and letting people get on with it. The way he trusts his team feels like a very modern yet mature way of building teams that give their most, great to work for.
- Fraser Brydson (2/23/09)
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