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Docetaxel, Thalidomide, Prednisone, and Bevacizumab to Treat Metastatic Prostate Cancer
- Full Text View
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- Study Results
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|Prostatic Neoplasms
|Drug: Docetaxel Drug: Thalidomide Drug: Prednisone Biological: bevacizumab Genetic: polymorphism analysis Other: immunoenzyme technique Other: laboratory biomarker analysis Other: pharmacological study
|Phase 2
|Study Type:
|Study Design:
|Allocation: Non-Randomized
Intervention Model: Parallel Assignment
Masking: Open Label
Primary Purpose: Treatment
|Official Title:
|A Phase II Trial of Docetaxel, Thalidomide, Prednisone and Bevacizumab in Patients With Androgen-Independent Prostate Cancer
- Number of Participants Who Had a Prostate-specific Antigen (PSA) Response [ Time Frame: 21.6 months ]PSA response was assessed by the PSA Consensus Criteria. PSA decline is defined as a decline in PSA of at least 50% with no other evidence of disease progression.
- Immune Response [ Time Frame: 6 weeks ]Cellular immune response and cytokines were evaluated after two cycles of therapy in the expansion cohort. Those cycles included treatment with bevacizumab and docetaxel as a pre-medication.
- Number of Participants With Adverse Events [ Time Frame: 37 months ]Here is the number of participants with adverse events. For a detailed list of adverse events see the adverse event module.
- Time to Progression Using Bubley Criteria [ Time Frame: up to 40 months ]Time to disease progression was based on the Prostate-Specific Antigen (PSA) Working Group 1 Criteria (Bubley Criteria) and standard Response Evaluation Criteria in Solid Tumors (RECIST) for measurable disease. Per the criteria, investigators report at a minimum a PSA decline of at least 50% and this must be confirmed by a second PSA value 4 or more weeks later. Patients may not demonstrate clinical or radiographic evidence of disease progression during this time period.
- Disease Progression by Clinical and Radiographic Criteria Without the Use of Prostate-Specific Antigen (PSA) [ Time Frame: up to 34 months ]Clinical and radiographic response was measured by the Response Evaluation Criteria in Solid Tumors (RECIST) Criteria. Complete response (CR) is disappearance of all target lesions. Partial response (PR) is at least a 30% decrease in the sum of the longest diameter (LD) of target lesions. taking as reference the smallest sum LD recorded since the treatment started or the appearance of one or more new lesions. Stable disease (SD) is neither sufficient shrinkage to qualify for PR nor sufficient increase to qualify for PD, taking s reference the smallest sum LD since the treatment started. Progressive disease (PD) is at least a 20% increase in the sum of the LD of target lesions, taking as reference the smallest sum LD recorded or the appearance of one or more new lesions.
- Number of Participants Who Died After a Follow Up of 34 Months Following Treatment [ Time Frame: 34 months ]From on study date to date of death at 34 months.
- Plasma Concentrations of Docetaxel and Thalidomide and Clinical Activity or Toxicity [ Time Frame: Pre-dose on C1D1, 5 minutes before the end of infusion, and 15, and 30 minutes, and 1, 2,4,8, and 24 hours after the end of infusion ]The analysis will be performed using a validated method based on liquid chromatography with mass-spectrometric detection.
- Number of Participants With a Significant Increase in Circulating Apoptotic Endothelial Cell (CAEC) Level [ Time Frame: Baseline and at 6 weeks (after two cycles of treatment) ]The assay utilized has no standard curve. Categorizing patients with ≥ 75% PSA decline in one group and < PSA decline in another group, every patient is their own control with comparison of CAEC at baseline vs. 6 weeks (after two cycles of treatment). Blood is drawn from the patient and a million viable mononuclear cells are counted and then it is determined how many CAECs are in the specimen. The cell count is then compared from baseline to post 2 cycles of treatment. Thus, "significant increase" is dependent upon this comparison and varies between patients.
- Analyze the Patients Genotype With Regard to Cytochrome P450 2C19 Polymorphism and Correlate That With Pharmacokinetics and Efficacy [ Time Frame: Patient entry onto the study ]Single nucleotide polymorphisms in genes that play an important role in eliminations pathways for docetaxel (in the CYP3A4 and CYP3A5 genes) and thalidomide (CYP2C19) will be evaluated.
- Usefulness of Dynamic Magnetic Resonance Imaging (MRI) to Monitor the Progression of Bony and Soft Tissue Disease in Metastatic Prostate Cancer [ Time Frame: Baseline and at 3 month intervals until progression ]Target lesions in the bone or soft tissues will be identified from the participant computed tomography (CT) scan. Dynamic MRI will be performed after the intravenous administration of 0.1 mmol/kg of Gadolinium chelate. Progression is defined by the RECIST criteria and is at least a 20% increase in the sum of the longest diameter (LD) of target lesions, taking as reference the smallest sum LD recorded since the treatment starts or the appearance of new lesions.
- Changes in the Molecular Markers of Angiogenesis (Including, But Not Limited to Serum and Urine Vascular Endothelial Growth Factor (VEGF)) Before and After Administration of Docetaxel, Prednisone, Thalidomide and Bevacizumab [ Time Frame: Baseline and monthly ]
|Study Start Date:
|August 2004
|Estimated Study Completion Date:
|January 2018
|Primary Completion Date:
|December 2011 (Final data collection date for primary outcome measure)
|Assigned Interventions
Experimental: Main cohort - Prostate Cancer
Docetaxel 75 mg/m^2 intravenously over 60 minutes on cycle 1 day 1 repeated every 21 days. Thalidomide 200 mg by mouth daily throughout the cycle. Prednisone 10 mg by mouth daily throughout the cycle. Bevacizumab 15 mg/kg intravenously on cycle 1 day 1 every 21 days.
Drug: Docetaxel
Docetaxel 75 mg/m^2 intravenously over 60 minutes on cycle 1 day 1 repeated every 21 days.
Other Name: TaxotereDrug: Thalidomide
Thalidomide 200 mg by mouth daily throughout the cycle.
Other Name: ThalomidDrug: Prednisone
Prednisone 10 mg by mouth daily throughout the cycle.
Other Name: DeltasoneBiological: bevacizumab
Bevacizumab 15 mg/kg intravenously on cycle 1 day 1 every 21 days.
Other Name: AvastinGenetic: polymorphism analysis
Two buffy coat tubes (two 7mL blue tiger top tubes) will be obtained and wrapped in foil when the patient enters onto the study. DNA (deoxyribonucleic acid) will be isolated only for the purpose of genotype analysis of enzymes with putative relevance for docetaxel or thalidomide disposition.Other: immunoenzyme technique
The PBMC (peripheral blood mononuclear cells) of patients will be analyzed pre-treatment and post cycle 2 for any changes in the function of regulatory T cells. The following analysis will be performed: flow cytometry analysis, CD4 CD25 T cell enrichment, and immunosuppression assay.Other: laboratory biomarker analysis
Serum and urine samples will be collected at baseline and monthly to measure VEGF (vascular endothelial growth factor) levels.Other: pharmacological study
Plasma concentrations of docetaxel and thalidomide will be determined to assess interactions between docetaxel (and thalidomide) and the concomitant therapy.The analysis will be performed using a validated method based on liquid chromotography with mass-spectrometric detection.
Experimental: Expansion cohort - Prostate Cancer
Docetaxel 75 mg/m^2 intravenously over 60 minutes and Bevacizumab 15 mg/kg intravenously was given for 2 cycles. After two cycles Prednisone 10 mg by mouth daily and Thalidomide 200 mg by mouth daily was added.
Drug: Docetaxel
Docetaxel 75 mg/m^2 intravenously over 60 minutes on cycle 1 day 1 repeated every 21 days.
Other Name: TaxotereDrug: Thalidomide
Thalidomide 200 mg by mouth daily throughout the cycle.
Other Name: ThalomidDrug: Prednisone
Prednisone 10 mg by mouth daily throughout the cycle.
Other Name: DeltasoneBiological: bevacizumab
Bevacizumab 15 mg/kg intravenously on cycle 1 day 1 every 21 days.
Other Name: Avastin
Detailed Description:
|Ages Eligible for Study:
|18 Years and older (Adult, Senior)
|Sexes Eligible for Study:
|Accepts Healthy Volunteers:
Androgen-independent metastatic adenocarcinoma of the prostate defined as progressive metastatic disease while on gonadotropin releasing hormone (GnRH) agonists or post surgical castration
Histopathological documentation of prostate cancer confirmed in the National Cancer Institute (NCI) Laboratory of Pathology at the National Institutes of Health, the Pathology Department at Walter Reed Medical Center or the Pathology Department at National Naval Medical Center, prior to starting this study. In addition, patients whose slides are lost or unavailable will be eligible for the study if they provide documentation of prostate cancer and if they meet criteria of clinically progressive prostate cancer as outlined in section 18.104.22.168.
Clinically progressive prostate cancer documented prior to entry. Progression must be documented by at least one of the following parameters:
- Two consecutively rising prostate-specific antigen (PSA) levels. The first rising PSA must be a minimum of one week from a reference value. It is recognized that PSA fluctuations are such that the confirmatory PSA value might be less than the previous one. In these cases, that patient would still be eligible provided the next PSA was greater than the first rising PSA value. Patients must have PSA greater than or equal to 5.0.
- At least one new lesion on bone scan.
- Progressive measurable disease.
Patients must have undergone bilateral surgical castration or must continue on GNRH agonist.
Those patients receiving an anti-androgen agent and are entering the trial due to a rise in PSA must demonstrate a continued rise in PSA 4 weeks after stopping flutamide and 6 weeks after stopping bicalutamide or nilutamide.
Patients may not have received any chemotherapy for metastatic prostate cancer
Age greater than or equal to 18 years
Eastern Cooperative Oncology Group (ECOG) performance status less than or equal to 2
Life expectancy of greater than 3 months
Patients must have adequate organ and marrow function as defined below:
Leukocytes- greater than or equal to 3,000/microliter
Absolute neutrophil count- greater than or equal to 1,500/microliter
Platelets- greater than or equal to 100,000/microliter
Hemoglobin- greater than or equal to 8.0g/L - transfusions acceptable
Total bilirubin- less than or equal to 1.5 times the institutional upper limits of normal
Aspartate aminotransferase (AST)serum glutamic oxaloacetic transaminase(SGOT) and alanine aminotransferase (ALT)serum glutamic pyruvic transaminase(SGPT) - less than or equal to 2.5 times the institutional upper limits of normal
Creatinine or Creatinine clearance- less than or equal to 1.5 times the institutional upper limits of normal or greater than or equal to 40 mL/min/1.73 m^2 for patients with creatinine levels above institutional normal.
Recovered from any toxicity from surgery or radiotherapy
Must be willing to travel from their home to the National Institutes of Health (NIH) for follow-up visits
Able and willing to follow instructions and conform to protocol.
Patients may have had no other active malignancy within the past 2 years with the exception of non-melanoma skin cancer and superficial bladder carcinoma
No history of myocardial infarction within the past 6 months, uncontrolled congestive heart failure (CHF) or uncontrolled angina pectoris
Patients must agree to use adequate contraception (abstinence; hormonal or barrier method of birth control) for the study and at least 2 months after completion.
Ability to understand and the willingness to sign a written informed consent document.
Present clinical signs or symptoms of brain and/or leptomeningeal metastases confirmed by computed tomography (CT) or magnetic resonance imaging (MRI) brain scan.
Uncontrolled, intercurrent illness including, but not limited to, ongoing or active infection, symptomatic congestive heart failure (American Heart Association (AHA) Class II or worse), unstable angina pectoris, cardiac arrhythmia, or psychiatric illness/social situations that would limit compliance with study requirements
Persistent systolic blood pressure greater than or equal to 170 mmHg or diastolic blood pressure greater than or equal to 100 mmHg.
Human immunodeficiency virus (HIV)-positive patients receiving combination anti-retroviral therapy are excluded from the study because of possible pharmacokinetic interactions with docetaxel, bevacizumab, and/or the combination.
Proteinuria, as demonstrated by a urine, protein, creatinine (UPC) ratio greater than or equal to 1.0 at screening, required to be assessed if urine dipstick is greater than or equal to 1+.
Urine protein should be screened by urine analysis for Urine Protein Creatinine (UPC) ratio. For UPC ratio > 0.5, 24-hour urine protein should be obtained and the level should be < 1000 mg for patient enrollment. Note: UPC ratio of spot urine is an estimation of the 24 urine protein excretion - a UPC ratio of 1 is roughly equivalent to a 24-hour urine protein of 1 gm. UPC ratio is calculated using one of the following formula:
- [urine protein]/[urine creatinine] - if both protein and creatinine are reported in mg/dL
- [(urine protein) x 0.088]/[urine creatinine] - if urine creatinine is reported in mmol/L
Therapeutic anticoagulation with coumadin, heparins, or heparinoids.
Greater than Grade 2 peripheral neuropathy at baseline.
History of transient ischemic attacks (TIA) or cerebrovascular accident (CVA) within the past 2 years.
History of allergic reaction to docetaxel, prednisone, thalidomide and/or bevacizumab or related products.
Patients who are on concurrent investigational agent(s)
Patients who are unable to ingest oral medication.
Men of all races and ethnic groups are eligible for this trial. Every effort will be made to recruit minorities in this study. Women are ineligible for this study.
Please refer to this study by its ClinicalTrials.gov identifier: NCT00089609
|United States, Maryland
|National Institutes of Health Clinical Center, 9000 Rockville Pike
|Bethesda, Maryland, United States, 20892
|Principal Investigator:
|William L Dahut, M.D.
|National Cancer Institute (NCI)
Additional Information:
|Responsible Party:
|William Dahut Jr., M.D., Principal Investigator, National Institutes of Health Clinical Center (CC)
|ClinicalTrials.gov Identifier:
|NCT00089609 History of Changes
|Obsolete Identifiers:
|Other Study ID Numbers:
|Study First Received:
|August 6, 2004
|Results First Received:
|October 12, 2012
|Last Updated:
|September 16, 2016
|Individual Participant Data (IPD) Sharing Statement:
|Plan to Share IPD:
Keywords provided by William Dahut Jr., M.D., National Institutes of Health Clinical Center (CC):
Prostate Cancer
Additional relevant MeSH terms:
Prostatic Neoplasms
Genital Neoplasms, Male
Urogenital Neoplasms
Neoplasms by Site
Genital Diseases, Male
Prostatic Diseases
Angiogenesis Inhibitors
Angiogenesis Modulating Agents
Growth Substances
Physiological Effects of Drugs
Growth Inhibitors
Antineoplastic Agents
Tubulin Modulators
Antimitotic Agents
Mitosis Modulators
Molecular Mechanisms of Pharmacological Action
Anti-Inflammatory Agents
Hormones, Hormone Substitutes, and Hormone Antagonists
Antineoplastic Agents, Hormonal
Immunosuppressive Agents
Immunologic Factors
Leprostatic Agents
Anti-Bacterial Agents
ClinicalTrials.gov processed this record on July 25, 2017


text: You love the Aloft or you hate it. The amenities that make an Aloft an Aloft are great to some and perhaps annoying to others. Here are a few. The interior spaces look like they were furnished entirely out of the IKEA catalog. Guest room interiors are minimalist – most surfaces are formica; floors are a mix of ceramic tile... More

subset: commoncrawl


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Prop boundary condition
Hi everyone,
I'd like to model the aerodynamics around a small plane. The thing is that I don´t know how to model the propeller of the plane, I mean, what is the most suitable geometry and boundary condition. I wander if a circle conditioned as intake fan would work, but I've tried and the path lines seems to be not disturbed by this (no helicity, or rotating components of velocity).
Can anyone help me?
Thanks in advance
Re: Prop boundary condition
I think you have two options...
1. Use the fan BC and specify the Swirl-Velocity. To use this, the circular fan BC must have fluid zones on both sides. This should twist the pathlines, etc.
2. Mesh the actual props and use a MRF to rotate that zone. This will probably give you more accurate results, but will significantly increase the size of your mesh.
|All times are GMT -4. The time now is 19:30.


text:
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Site Search
Welcome to Global Member Care Network
The Global Member Care Network connects you with resources, updates, links and people working in the realm of member care around the world.
In order to facilitate better interaction and community,
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text:
3 December 2007,
New York
Price realised USD 1,625
BURNS, Robert (1759-1796). Poems Chiefly in the Scottish Dialect. Edinburgh: for the author, and sold by William Creech, 1787.
8o (225 x 146 mm). Half-title. Stipple-engraved frontispiece portrait by J. Beugo after A. Nasmyth. Contemporary calf (front cover detached, worn) Provenance: A.K. Coton (early signature on front pastedown).
Second (first Edinburgh) edition, this copy with "Boxburgh" instead of "Roxburgh" in the list of subscribers but with "skinking" correctly spelled on page 263. Wilson declined to print the second edition since Burns was unable to advance the £27 needed for enough paper to print a thousand copies. The immense number of subscribers eventually necessitated a run of 3000 copies which were printed by William Smellie of Edinburgh and published on 17 April 1787. Subscribers paid 5 shillings, non-subscribers 6 shillings, per copy. Creech took 500 of the 2876 copies subscribed for, but his delay in settling accounts led Burns to express the wish that he be "streekit out to bleach/In winter snaw." This second edition contained 22 additional poems, the original preface was replaced by a 4-page dedication to the members of the Caledonian Hunt, the list of subscribers ran to 38 pages, and the glossary was also enlarged. Egerer 2; Rothschild 556; Tinker 452.
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Pre-Lot Text
Bidders from 65 countries take part in the 11 sales, with Guardi's Venice: The Rialto Bridge setting the highest auc..
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Beyoncé Wants To Buy A 123-ROOM Mansion For When Her Twins Arrive
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Beyonce's daughter Blue Ivy Carter is almost 18-months-old! Take a look at these beautiful pictures of the world's most famous baby and her mum...
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In case you haven't heard, Queen Bey stole the show. But we really wouldn't expect anything less...
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Business Law
Ask a Business Lawyer. Get Business Law Questions Answered ASAP.
Fact: I have C corporation where there are 65 voting/active shares and 35 Treasury stock shs. There are 35 non voting shares or Preferred stock- not sure as to the right term No stock certificates have been issued. There is a paper on file, signed by alll parties acknowledging these facts. In addition: A contract was signed by 3 of the voting shareholders that represent the 65 shares: 30 shs- Shareholder A, /22 shares to B (plaintiff) and /13 shares for C To facilitate the decision process the contract "specifically" states: Shareholder A makes all decisions concerning the dance studio's operations. Shareholder B makes all decisions concerning Administartion and Event venues. Shareholder A & B are responsible for any deficit in the monthly expenditures. Shareholder C is not responsible for any monetary shortfalls. Shareholder C would only be involved with non related issues and would be the deciding vote if A & B could not agree to these unrelated issues. All three guarantee the lease for the property in which the company was operating from. Shareholder A in conjunction with C representing 43 shares decided to remove B (22 shs)from the checking account and changed the locks on the facility. There was no reason given, no meeting held and no minutes recording their action. To add insult to injury, because of correspondence that was initiated by Shareholder B, A & C hired an attorney and the back and forth letters have produced nothing but back and forth accusations. In addition A & C have opened and have been operating under a similar name, and potentially using a different bank account under such name in the same operation of business at the same location. There is only one debt of $12,000 since all purchases and construction totalling $250,000 was paid in cash. They claim the business is worth zero. I made an offer to buy their shares out. They never asked for how much. They want the corporation and it appears they want to do me out of my investment of $40,000. There is also a provision in the lease which B is responsible for, that no sub lease can be arranged unless approved by the landlord and naturally by B. Landlord was informed and is following through. Shareholder B now has to either seek council or go it alone on a solid case. Shareholder B realizes that Civil Court is for amounts up to $15,000 and will seek that amount, and if the initial law suit does not get their attention, a request will be made to transfer it to circuit court where the amount is in excess of $15,000. Here is what shareholder B wishes to present to the courts in the action: 1. Breach of Contract 2. Fraud for opening another corporation and claiming the company is worth nothing. 3. Embezzlement- for the use of previous accounts income to fund the new corporation and make payment to their employees and personal income to A. Questions: 1. Are the charges accurate? 2. Are there any additional charges applicable? 3. Since the courts determine how to proceed, does a specific monetary amount necessary since there are potential criminal charges. 4. How does B get a court order (immediately) to cease the illegal operation of anothe corporation If B could afford $10,000 (initially) in legal cost an attorney would be hired. I believe getting their attention and having them incur legal cost in hiring an attorney for the corporation, may do the trick. If not B will not proceed without legal representation. I hope I covered it all. I am waiting for your input. Thank You Joe
I am willing to pay a bonus. How much?
You can claim fraud, but you should add a claim for conversion - taking your property, also breach of fiduciary duty, breach of duty of loyalty, there are probably more, but those are the first that come to mind. They did not have the authority to change the locks. You are on the lease and would have to be evicted, which would be very tough in this case when you own the tenant as a shareholder.
You need an injunction to stop them form stealing your business. The are doing irreparable harm to your business interests and reputation.
Also known as a cease and desist. You will need a lawyer for this.
You have a good case. Would you consider hiring someone on a contingency basis?
I would go straight to the circuit court and claim in excess of $15,000. You should take these guys to the cleaners. They totally ripped you off and you can prove it. Changing the locks was over the top.
Thank you for using JustAnswer! Please click "Accept". If you need more, just let me know.
You can win. Go for $1 million. They stole your business and acted in total bad faith.
Yes, contingency is an option I would entertain.
In addition, there is one partner who has a house worth $250,000, age 74 and the other one has maybe $25,000.
Now you need to find the right lawyer to take the case and run with it. Agree to pay court costs and give them 25-33%. They both have cash too. You also have the restraining order route, which should get you back in there.
I realize the severity of their actions, and the amount of a financial recovery is minimal and that is the reason I am questioning the cost factor.
Does your organization have any lawyers that would take this on a contingency basis?
Yes, but we are not admitted in FL. Try the local bar association lawyer referral service for starters.
You may have to hunt around for a while, but when you tell them that the defendants have money and a profitable business is involved, you will get their attention. They have to see money to be interested, sad to say.
What about the injuction? Would you be happy taking the business back?
Other then what I mentioned, what would be the easiest way to proceed to initiate a court action?
Court action under $15000 on my own?
Go straight to suing them. That is the only kind of logic they will understand. You could enjoin them from running the business but that will ultimately hurt their ability to pay.
If that is all you think is worth, then yes.
Thank You


text:
This category contains articles about player races unique to SLASH'EM.
"Doppelgangers can polymorph into any of the permitted monsters with the extended command...Doppelganger (starting race)
"Lycanthropes are a new race specific to SLASH'EM. Lycanthropes are always chaotic and can play...Lycanthrope (starting race)
"The drow is a race specific to SLASH'EM, most noted for their bare-handed sleep attack. While...Drow
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Pages in category "SLASH'EM races"
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text: Fairchild Semiconductor (NYSE: FCS), the leading global supplier of power semiconductors, today announced results for the second quarter ended July 1, 2012. Fairchild reported second quarter sales of $361.5 million, up 3 percent from the prior quarter and 17 percent lower than the second quarter of 2011. Adjusting for the extra week in Fairchild's fiscal first quarter, sales grew 11 percent sequentially. Second quarter revenue includes approximately a $4 million insurance recovery related to the Thailand flooding. Fairchild reported second quarter net income of $11.9 million or $0.09 per diluted share compared to $1.6 million or $0.01 per diluted share in the prior quarter and $44.9 million or $0.34 per diluted share in the second quarter of 2011. Gross margin was 32.6 percent compared to 29.8 percent in the prior quarter and 37.1 percent in the year-ago quarter. Fairchild reported second quarter adjusted gross margin of 32.6 percent, up 280 basis points sequentially and down 460 basis points from the second quarter of 2011. Adjusted gross margin excludes accelerated depreciation related to fab closures. Adjusted net income was $17.6 million or $0.14 per diluted share, compared to $8.3 million or $0.06 per diluted share in the prior quarter and $54.6 million or $0.41 per diluted share in the second quarter of 2011. Adjusted net income excludes amortization of acquisition-related intangibles, restructuring and impairments, accelerated depreciation related to fab closures, write off of deferred financing fees, charges for litigation and associated net tax effects of these items and other acquisition-related intangibles. "We reported solid sequential sales growth in the second quarter despite a challenging macro-economic environment," said Mark Thompson, Fairchild's president and CEO. "Distribution sell-through increased more than 14% from the prior quarter after adjusting for the extra week in Q1. Demand continues to be strong for our mobile and mid-voltage product lines. We are confident we can grow our sales into the mobile end market in the second half given our backlog and design win pipeline at key customers. While we believe we can increase sales in other end markets as well, our guidance reflects a healthy level of conservatism given the current economic uncertainties."


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"I love watching fish swim in and out of the reef heads, it just shows how alive the water is and its like watching an underwater dance."
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This underwater marine life photograph taken by Zak Noyle shows a school of small blue fish leaving the safety of their coral home for a swim in Tahiti waters.
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I don't know if anyone knows they are truly ready for a baby.
I'm going to go with the same sentiment expressed by the other ladies here, and say I don't think you ever know you're ready for a baby because you probably never really are completely ready.
Sure, it's nice to be 'stable' so you can bring baby into a good environment, but I don't think that really qualifies you as 'ready.' If you're emotionally stable, I feel like hormones and sleep deprivation will go ahead and mess with that. Financially stable... sure, that'll help, but babies are still expensive. Relationship, I feel like it's going to be a stress even on the closest, most communicative relationships. It's a HUGE change.
Of course, some people handle change better than others, but I think the perspective pre-child is hard to align with what life will actually be like. There's a whole different perspective between TV, or having friends with kids and baby sitting.. and LIVING it 24/7/365 for the rest of your life. I would wager to say having a child is THE biggest decision you can make.
Buying a house and things of that nature, I mean, yeah... That's big. It's a pretty big investment and commitment. But, if you don't like being a homeowner, you can sell. I guess you can give your kid up for adoption too.... But, you're still a mom. (And how many moms will really be willing to do this if you decide being a parent is 'too hard' when your kid is a toddler or something... Seriously.) You still made a PERSON (which, by the way, still amazes me.) Who can honestly say they are fully, completely, 100% ready for that kind of responsibility?
I'm not. I know I'm not. So does my husband. But, we're ready ENOUGH, and I think, especially when it comes to having kids... Good enough has to be just that, good enough. It'll have to be when the floor is a little sticky. It'll have to be when your clothes can't be perfect because they've got spit-up on them. And the fact that there's a bajillion conflicting views on how to do everything with a kid... Good enough is GOOD.
Learning to do good enough now I think is the best option, or it's gonna be 'good enough' when you're rocking in the corner, mumbling incoherently because you lost your mind trying to make everything PERFECT, lol.
Were you completely ready for it when you had your first baby? (Or your second, or your third) Is there any way to be ready or any ways that you know you are?


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Elegy is the ECM leader debut by vocalist and composer Theo Bleckmann. A prolific recording artist, his association with the label dates back to Meredith Monk's 2002 date Mercy and its follow-up, Impermanence, in 2008 (Bleckmann was a member of her ensemble for 15 years). His voice was also a focal point of Julia Hulsmann's quartet on 2015's Clear Midnight: Kurt Weill & America. For a singer who draws attention to himself almost as much for what he doesn't do as what he does, Elegy is a quiet yet startling offering.
Excellent addition to any prog rock music collection.
Although admittedly a posthumous release, I was very surprised at the rather dismissive tenor of many of the reviews of this album to date. Hopefully this record will be reappraised soon as being a release worthy of anyone's consideration as I feel it does enhance an already rich legacy left behind by this very fine and innovative band. (So what if Charisma wanted to ride the slipstream of the lucrative ELP juggernaut?)
Coban and his four comrades are smugglers who live in the bleak, inaccesable mountains. They are hard, pitiless men like the county they live in, whose daily commerce is in greed, danger, betrayal and murder.
In Okayama in the mid-1930s, Kiroku attends high school and boards with a Catholic family whose daughter, Michiko, captures his heart. He must, however, hide his ardor and other aspects of his emerging sexuality, focusing his energy on a gang he joins, breaking school rules, and getting into scuffles (he tells her, "Oh, Michiko, I don't masturbate, I fight"). He comes under the influence of a young tough nicknamed Terrapin, and together they lead fights against rival gangs. Gradually, Kiroku and Terrapin align themselves with the right-wing Kita Ikki, and Kiroku becomes a stand-in for the attitudes of Japanese youth who embraced the imperialism leading to World War II.


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I'm curious as to what beta testers are seeing in regards to performance with 5.0. I'm hoping it's a vast improvement over the current version.
Thank you.
5 Replies
Sep 29, 2010 at 9:26 UTC
You better believe it ;)
Sep 29, 2010 at 9:26 UTC
I just answered my own question. Nice feedback!!!
Sep 29, 2010 at 9:26 UTC
I'm finding it considerably faster than 4.7 was...
The new features are excellent. The highlights of what I've found to be beneficial are:
- AD integration - users are automatically setup to login to the portal, and when configured properly, can have their passwords reset from within Spiceworks. Bonus on this, they are searchable from the main search bar.
- Scanning seems faster...responsiveness of just about everything is noticeably faster.
Sep 29, 2010 at 9:27 UTC
Thanks for the response! :)
Sep 29, 2010 at 9:30 UTC
I am seeing a huge speed improvement - pages loading in under a second and everything is very responsive - no more 'pregnant pauses' when a button is clicked. I am guessing that when I put the final version into production some of that will disappear, but compared to 4.7 or older - the speed is awesome!


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trillbee wrote:It's a great idea! I also am a 90s kid and I really love playing SNES and other console games. I still like those old games compare to the games that we have today. Also, a lot of toy collectors search these kind of stuff. They shell out tons of cash to get a hold on these rare products. You also mentioned that "Video games are my line of selling as i know a lot about them". This factor will surely help you succeed since you will enjoy what you do and you know that you have a broad knowledge on what you are selling. Once your potential buyer saw that you know a lot about what you sell, you will surely gain their trust. This way, there would be a big probability that they'll buy your item.
Just to add: As a customer, I go for rare finds rather than the usual product that you can easily find. It gives me a great feeling everytime I purchase hard to find products. :)
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[Ended] Prediction Voting Event (October 21st ~ November 18th)
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GP2C is an official certifying
organization of the President's
Volunteer Service Award Program.
>> learn more
Girl Power 2 Cure, Inc. is a 501c3 nonprofit organization dedicated to raising awareness and funds for treatments and a cure for Rett Syndrome, a devastating neurological disorder that almost exclusively affects girls.
We are committed to making Rett Syndrome the first reversible neurological disorder by harnessing the spirit of girls to support fellow girls who are suffering. We support girls in the planning and implementation of events that raise awareness and funds for Rett Syndrome research, as well as support Rett families with resources, fundraising help and awareness tools.
Our inspiration is our flower: always in bloom with hope and positive energy, ready to grow anywhere there is someone ready to join in our mission.


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|Post Trn TipPost Trn Tip
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Blog Entry# 1977038
Posted: Aug 31 2016 (12:19)
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Journey: Tue Aug 30, 2016/
Class: AC 3-tier - 3A
Travel: GAYA/Gaya Junction to KYQ/Kamakhya Junction
Class: AC 3-tier - 3A
Travel: GAYA/Gaya Junction to KYQ/Kamakhya Junction
Entry# 1977038
PNR: 615-xxxxxxx | Similar PNRs
Posted Status as of: Aug 31 2016 (12:19)[[[PNR Fetching was not successful. One of our guests or members (using Google Chrome or Firefox) will soon click the Refresh button to fill in this BLANK PNR Status. Prediction and Analysis will commence thereafter. Please check back soon.]]]
Please analyze this PNR, and predict the final Charting Status. Thanks.
Latest Status as of: Aug 31 2016 (18:25)Passenger 1: B1,17 [LB]/Coach Position:12 (Booking Status: W/L 2,GNWL)
Passenger 2: B1,18 [MB]/Coach Position:12 (Booking Status: W/L 3,GNWL)
Total Fare: 2130
Chart PREPARED


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Home > Product Categories > Racks & Cases > Equipment Cases > Hard Shell & Waterproof Cases > 3I-1711-6B-D
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|Clare-Liam Friendship
|General Information
|Intimacy Level
|Kissed, acquaintances
|Friendship Started
|Should've Said No (2) (1113)
|Friendship Status
Friendship History
- They both worked on the newspaper though it's possible Liam quit.
- They are both friends with Wesley and Alli.
- Liam is the third character to kiss Clare in their first appearance, with the first two being Jake and Wesley.
- Liam's first and last lines were both said to Clare.


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West Memphis 3 Released
August 19, 2011 by USA Post
West Memphis 3 Released, After almost two decades behind bars, the "West Memphis 3? Have been released from prison. Damien Echols, Jessie Misskelley Jr. and Jason Baldwin were arrested in 1993 for the murder of three boys, Stevie Branch, Christopher Byers and Michael Moore. Echols was sentenced to death, while Misskelley and Baldwin received life sentences.
Case management by police and prosecutors has been a lot of scrutiny, and brought to light in both the HBO documentaries Paradise Lost and Paradise Lost 2, and a detailed book by journalist Mara Leveritt knot called Diablo.
At that time, but retracted Misskelley confessed later, his attorney argued that the confession was coerced and that police had pressured Misskelley due to their low IQ.
All three have maintained their innocence and freedom has become a cause celebre, being supported by websites, legal defense funds, and celebrity involvement.
It is due to different legal disputes and other evidence that has emerged since the state made to free the three, and the suspension of their sentences to avoid more lawsuits and appeals. Lawyers for the three had filed two motions – one of the misconduct of the jury, and the other asking the court to review the latest results of DNA tests that exonerated the men say.
In a rare legal maneuver, the three men maintained their innocence, but pleaded guilty and acknowledged that prosecutors had the evidence to convict them.
Echols, 36, Baldwin, 34, and Misskelley, 36, is processed and released on Friday afternoon. Provided they do not get into trouble for criminals, who remain free. Otherwise, they could face an additional 21 years in prison.
The prosecutor said he considered the matter closed and not pursue any other suspects in the killings. He said he "hoped and prayed" that the three men had been "rehabilitated" in his 18 years in prison. The plea agreement also protects the status of any litigation of wrongful imprisonment.
A hearing was announced on Friday surprise, and one of the victims' parents, Steve Branch, confirmed to reporters that the hearing will involve the release of at least two of the three.
The father of Jessie Misskelley KAIT-8 said he was disappointed his son had to plead guilty for his release.
Please feel free to send if you have any questions regarding this post , you can contact on
Disclaimer: The views expressed on this site are that of the authors and not necessarily that of U.S.S.POST.


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The Sims 4 Dine Out cd key for game Keygen – Serial
– download link + instruction
New Game Pack.
•► Download the The Sims 4 Dine Out CD-Key Generator and Open it
•► Choose the platform for which you want to get the key
•► Wait for the process to finish and go to Redeem your Code.
The Sims 4 Dine Out cd key for game Keygen – Serial
How to install:
1. Download and run exe file
2. Press Install button
3. Choose destination folder
4. Press Finish
How to Use:
Open destination folder and locate file notes.txt, open it and read step by step.
Download nowDirect download link (Windows) ]


text:
Chocolate Transfer Sheets
Decorating By alman Updated 22 Aug 2008 , 9:44pm by JodieF
Has anyone ever tried to use those chocolate transfer sheets by putting the sheet right onto crusted buttercream? I don't want to use the chocolate but really love the idea.
It's the heat of the melted chocolate that melts the pattern off the acetate. Without heat the pattern wouldn't transfer.
Quote by @%username% on %date%


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This is an assignment I did for class where I read one of L Frank Baum's OZ creations and made a world with in his world, using the rules, and ideas learned from my reading. I wrote a short travel log that summarizes my creation.
Travel Log
Traveling the mountains avoiding the Metal Monarch, I came across a wonderful village, found up in the mountains well above the ground. The people of the village were Nomes, not your typical angry Nomes , but happy Nomes, whom have been banished from the underground village they use to reside.
They have built into the stone, carving out their homes into the walls atop the mountain. The whole village surrounds a town hall.
The town hall at its very top point is the highest part of the mountain. It is built with a series of cascading stones, and in the walls, there are embedded crystals, and other minerals, allowing the interior of the building to light up during the day. These crystals and minerals represent the town's main source of trade, and their means of survival.
The town's leaders are the multiple personalities with in a single Nome named Scrum. Scrum has multiple personalities, for he was bounced around and hit his head too much in the rubber forest, so much that he became confused and ended up on the other side of the cavern and in the metal forest. He became lost and wandered for many years.
When he became so alone, he developed his own friends in his mind.
Scrum is the founder of the town, after he wandered upwards from the metal forest, and came out at the very top of the mountain. The town was created very fast, for each one of Scrum's personalities partook in the creation of the town, when one got tired the other would start working. You can see each of their personalities through the construction


text:
DENVER – Employers could open themselves up to discrimination claims, experts say.
This opinion piece looks at risk management through the lens of mobile remote deposits.
This opinion piece looks at the use of loan participations to leverage capital and spread risk.
ACH risks can be confusing and can vary with each type of transaction, according to CUNA Mutual Group.
ACH risks can be confusing and can vary with each type of transaction, according to CUNA Mutual Group.
New risk-management CUSO will offer ERM services, IT security, business continuity planning and other services.
Credit reporting agency credits lenders' risk assessment, portfolio management and credit availability for record numbers of auto loan originations.
ORNL Federal Credit Union in Oak Ridge, Tenn., has promoted Bronce Rodgers to the newly created position of vice president of loss mitigation.
This Opinion piece looks at how cloud computing can deliver business benefits, if accessed and used securely.
Regulatory & Risk Management Indicator debut finds growing concern over regulatory compliance, risk management among credit unions and banks.


text:
Rogue host route in IS-IS database
- Silver, 250 points or more
During the testing, a loopback address was added to a C6k box (running 12.2(18)SXF7). This loopback interface was marked as 'passive' within IS-IS and was entered into the IS-IS topology database and advertised to all other IS-IS peers. Subsequently, the loopback interface was removed (and configrmed with 'sh ip route', etc), but the route is still present in the IS-IS topology, and is being advertised to the rest of the network. Is there any way to remove this rogue host route without a restart of IS-IS on the box advertising the route?


text:
NHL roundup: Canucks clinch Northwest with win over Blackhawks
Credit: Unknown
VANCOUVER, British Columbia — Daniel Sedin had a goal and an assist to help the Vancouver Canucks lock up their fifth straight Northwest Division title with a 3-1 victory over the Chicago Blackhawks on Monday night.
Jannik Hansen and Zack Kassian also scored for the Canucks, who won their eighth in a row at home and are guaranteed of home-ice advantage in the first round of the playoffs.
Henrik Sedin added two assists and Cory Schneider made 24 saves for the Canucks, who have put some distance between themselves and slumping Minnesota in the past few weeks.
|The article you requested is no longer available on BostonHerald.com.


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Gracious Writer For God
by Everett, Betty S.;
In Stock - Usually dispatched within 24 hours
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Gracious Writer For God
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Gracious Writer For God by Everett, Betty S. was published by CLC Publications in August 2015 and is our 56269th best seller. The ISBN for Gracious Writer For God is 9780875086644.
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|Page last updated
|14th July 2017
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|Everett, Betty S.
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text:
Welcome to Thunderbird Add-ons.
Add extra features and styles to make Thunderbird your own.Close
Pan 2.7.2
by cstkingkey
Block ads and manage proxy.
This add-on has been marked as experimental by its developers
This add-on is not compatible with your version of Thunderbird because of the following:
About this Add-on
Pan allows you to block and hide advertisements on websites. And Pan allows you to use your proxy (http/socks) automatically & efficiently.
With subscriptions and customs rules, Pan will automatically block advertisements and switch your proxy status as well ad proxy servers. And it's very easy to customize the rules with useful features from Adblock Plus. The difference between adblocking rules and proxy rules is that proxy rules group's title shall have the prefix "[proxy]".
While Pan is fully compatible with Adblock Plus' filters, Pan does not have Adblock Plus' aceptable ads feature.
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text:
Hero: The Life and Legend of Lawrence of Arabiaby Michael Korda
From Michael Korda, author of the New York Times bestselling Eisenhower biography Ike and the captivating Battle of Britain book With Wings Like Eagles, comes the critically-acclaimed definitive biography of T. E. Lawrence—the legendary British soldier, strategist, scholar, and adventurer whose exploits as "Lawrence of Arabia"/b>/b>/b>
From Michael Korda, author of the New York Times bestselling Eisenhower biography Ike and the captivating Battle of Britain book With Wings Like Eagles, comes the critically-acclaimed definitive biography of T. E. Lawrence—the legendary British soldier, strategist, scholar, and adventurer whose exploits as "Lawrence of Arabia" created a legacy of mythic proportions in his own lifetime. Many know T.E. Lawrence from David Lean's Oscar-winning 1962 biopic—based, itself, upon Lawrence's autobiographical Seven Pillars of Wisdom—but in the tradition of modern biographers like John Meacham, David McCullough, and Barbara Leaming, Michael Korda's penetrating new examination reveals new depth and character in the twentieth century's quintessential English hero.
Editorial Reviews
The New York Times
The Washington Post
Book-publishing veteran and prolific historian Korda (With Wings Like Eagles: The Untold Story of the Battle of Britain,2009, etc.) offers a comprehensive, admiring treatment of one of England's most popular if controversial military celebrities, T.E. Lawrence (1888–1935).
The author does not restrain his enthusiasm for, and even awe of, his subject. He calls Lawrence's Seven Pillars of Wisdom (1927) "one of the great pieces of modern writing about war" and compares him with a dizzying range of characters, from Odysseus to Princess Diana. At first, Korda uses Joseph Campbell's work of comparative mythology, Hero with a Thousand Faces (1949), to provide a framework, then, mercifully, abandons it. The author begins during World War I with the involvement of the diminutive young Lawrence, still in his 20s, already fluent in Arabic and other languages and already an authority on the Middle East. Korda describes military and political maneuvers and then retreats to narrate Lawrence's complicated birth (his parents were not married), boyhood, education and young manhood. Throughout, the author emphasizes Lawrence's deeply troubled relationship with his mother, but he also underscores his ferocious work habits, enormously high pain threshold (captured by the enemy, he endured severe beatings and rape) and unique combination of modesty (he refused honors) and pride (he wrote many letters to newspapers and cultivated friendships with George Bernard Shaw, Lady Astor, Thomas Hardy and others). Lawrence's military and political successes in the Middle East are undeniable, but his postwar life was a disturbing mixture of depression, enormous celebrity, a deep ambivalence about routine military life (he was in and out of the RAF) and sexual confusions. A motorcycle accident killed him at age 46.
Though occasionally fawning, an accessible, textured story of one man who intimately knew the slings and arrows of outrageous fortune.
Product Details
- 9780061712623
- Publisher:
- HarperCollins Publishers
- Publication date:
- 11/01/2011
- Pages:
- 800
- Sales rank:
- 487,143
- Product dimensions:
- 5.31(w) x 8.00(h) x 1.28(d)
What People are Saying About This
Meet the Author
Michael Korda is the author of Ulysses S. Grant, Ike, Hero, and Charmed Lives. Educated at Le Rosey in Switzerland and at Magdalen College, Oxford, he served in the Royal Air Force. He took part in the Hungarian Revolution of 1956 and on its fiftieth anniversary was awarded the Order of Merit of the People's Republic of Hungary. He and his wife, Margaret, make their home in Dutchess County, New York.
Customer Reviews
Average Review:
Most Helpful Customer Reviews
See all customer reviews
Previous reviewers seem to using the review space to express displeasure with the ebook price. I'm going to comment on the book. I've read a lot of Lawrence biographies and other work on his life and achievements. This one is the latest, and takes advantage of the release of many previously restricted files on Lawrence and his official actions in WW1. Korda has also read many of the letters Lawrence wrote throughout his life and has made some analysis of the circumstances in which they were written and Lawrence's relationship with the recipients. I found this book lucid and clear in expression and carefully researched and thought. The last section has analysis of some of the earlier biographies which often had obvious and varied agendas; Korda hoped, I am sure, to avoid this. Lawrence was never a take him or leave him person at any time. This is a must read for anyone interested in Lawrence or in the Middle East - the section on the Paris Peace Conference in 1919 is enlightening. Decisions made there are still giving trouble today, and Lawrence clearly felt he failed the Arab people. Korda has given us an illuminating view of a complex man and a life that resonates more that 75 years after it ended.
T.E. Lawrence is often portrayed as an enigma in the various biographies that have examined his life. Hero parses out Lawrence in an even-handed manner that allows the reader to walk with Lawrence as he struggles with the Arab question at the end of the First World War and then Lawrence's personal demons that assailed him after the war's conclusion. Studying Lawrence's involvement in the war is essential to understanding the Middle East today and the use of guerilla warfare all over the world. Korda's book is a great place to start before you engage lawrence's Seven Pillars of Wisdom.
Alas, this is the book that should have won the Pulitzer for history instead of the polemic by Stacey Schiff on Cleopatra. In my youth, (AKA 1960's-70s), I tried to read "Seven Pillars of Wisdom" but Lawrence's reputation had been severely damaged by questions as to the accuracy and honesty of his own account of the Great War. I couldn't rightly judge the integrity of what I was reading, that, and Lawrence liked to immitate the ponderous style of Doughty's "Arabia Deserta." Korda covers these issues of accuracy and redeems Lawrence's stylistic eccentricities with many examples of his strength of description. Lawrence is an extraordinary man with extraordinary personal baggage. But Korda treats his subject with compassion and sympathy without becoming maudlin. He puts Lawrence's accomplishments in perspective, and gives us a picture of a shy, insightful man, full of very human contradictions who was a natural born leader. Taking advantage of long withheld archival information and other sources, he brings a clarity to his subject that has long been needed. This is a highly readable account worth the price of admission. In fact, I could hardly put the book down, and at just one page short of 700, that's saying something. Korda is honest and doesn't clutter his work with anachronsitic judgements, (unlike Ms. Schiff who likes to drag Edward Said into her account whenever she can). After I finished the book I decided to go out and get a copy of Korda's biography of Eisenhower. A good historian!
Great book, however, the e-reader version is just too distracting with mistakes. Too many words running together. I have not found one page without this problem. Yes, I can figure out the words but that's not the point. There simply should not be these mistakes with an e-book priced at 20 dollars. And on page 329 it just jumps to who knows where. Really shows the HarperCollins just doesn't care. Sucks when a publisher ruins a otherwise great book.
"Hero: The Life and Legend of Lawrence of Arabia" by Michael Korda is a biography of Englishman Thomas Edward (T.E.) Lawrence better known by his nickname. The biography follows Lawrence from his birth to his early death. T.E. Lawrence was the illegitimate son of an Irish landowner who ran off with the family governess, Sarah Lawrence. They settled in Oxford, England using her name and brought up five sons, Thomas Edward being the second. From the start his mother had a difficult time accepting that Thomas will be different. Thomas got interested in medieval architecture and toured studying castles all over the world on many grueling journeys, walking alone much of the way. As World War I broke out, Lawrence's knowledge of the Ottoman Empire ensured him a post as an officer in Egypt and he quickly became the link between the British and the Arab revolt and becomes known to the world as Lawrence of Arabia. "Hero: The Life and Legend of Lawrence of Arabia" by Michael Korda is an amazing biography of a very complex man. After reading this book I finally understood the allure of Lawrence of Arabia: as ambiguous as he was in his lifetime, he is just as much ambiguous in his death. Mr. Korda does an excellent job examining the different, often contradictory, sides of this complex man. Lawrence was an Oxford educated scholar with special interest in archeology and an imperialist, but he was also a ruthless warrior who supported a revolt against the empire. Fighting against the Turkish Ottoman rule Lawrence acted in a brave fashion which could also be described as fanatic and quite irresponsible. T.E. Lawrence was a sexually repressed vegetarian who would eat meat not to insult his Arab hosts, hated physical contact but didn't flinch when charging the enemy. "detractors and admirers alike tend to dissect his personalty into thin slices, separating the soldier form the scholar, the hero for the teller of tall tales, the victim of neuroses from the moan of action, and in the process losing sight of just what an attractive and interesting person he was." The author does an excellent job bringing the reader the many sides of Lawrence, from admiration "cool judgment under fire" to the introducing a complex man, depressed, shy but certainly eccentric. The T.E. Lawrence we learn about has "found himself in part of the world where his taste for sweet things and his dislike of alcohol were shared by most of the local population". Mr. Korda does a wonderful job describing Lawrence's harassment and sabotage campaign (basically hit and run tactics) using a small force which, by nature, was much more mobile than the Turkish standing army. A poignant part of the book comes when describing Lawrence's capture, torture and rape by the Turks. This was a life changing event for Lawrence and the humiliation he felt for enjoying the rape has haunted him to the end. Michael Korda treats this pivotal occurrence in Lawrence's life with sensitivity and seriousness it deserves. The transformation of T.E. Lawrence into the mythical Lawrence of Arabia mostly by Lowell Thomas is also a part of the story. However the author is quick to point out that the lure of his character does not overshadows Lawrence's real achievement, such as pioneering a new kind of warfare and his pivotal rule in creating three Middle Eastern kingdoms.
....especially in the footnotes. Most of the errors are mistakes in capitalization and I found it distracting at times. I don't know if that's just the ebook version, or if the hardback is the same way. Shame on you, HarperCollins. I've read a few Lawrence biographies (none recently)and I like this one the best. Korda does an excellent job of juggling Lawrence's private and public lives with the complexities of the era, and gives us a little insight into the current mess. ("Messpot," is one of the names Lawrence used for the Middle East - for "Mesopotamia" - and it fits as well now as it did then, sadly.) "Hero" is so information-dense that I had to read a lot more carefully than usual. I even went online a couple of times to get a bit more depth on a subtopic than Korda was able to squeeze into a book that already runs to 700+ pages. I get the impression that Korda really enjoyed doing this one, the enthusiasm he has for his subject shows. Highly recommended.
I've read Seven Pillars of Wisdom and another excellent biography of Lawrence (one by Jeremy Wilson). This biography is mostly disappointing. It appears as if the author used the movie Lawrence of Arabia (1962) as a basis and then filled in with additional information. A good version for those that have not read the story (or seen the film) but disappointing otherwise.
Well written and exhaustedly detailed, I thourghly enjoyed this read. Generally it reads like fiction by is loaded with history. Some parts were slow but overall it afforded the often overlooked part of the birth of the modern day Middle East and the role of England in it. The real Lawrence; a real man whose vision shaped the world.
A very long and tedious book. Hard together through for the most part even though I was looking forward to reading the book. I did enjoy learning more about his family, what drove him and his sometimes unusual personality.
This book answered all of the questions I had after reading Seven Pillars. I know there are some biographers of Lawrence who seem to want to disparage him in some way or another, but in this volume Michael Korda seems to be pretty even-handed. If you've wondered about where T.E. Lawrence came from before the Arab Campaign or where he went after, this book is a good choice.
The book makes for an interesting read about a fasinating man and time. Too bad the typos were soooooo prolific. It became distracting from the overall read and NOT worth the money spent on it.
Great book. It's long. Goes into great deal of history on his life. Still hard to put your finger on Lawrence-truly a great hero with as many oddities as strong character traits. Enjoyable thru the end!
T.E. Lawrence is a fascinating topic. A complex person with unique views and strong feelings. This book is a scholarly work on his life. Rich with accurate detail but weak in "friendly" presentation. Hard to read. I enjoyed learning about the subject but wish for more pleasure in the reading.
I just finished reading the hard cover version of the book and was felt it was worth every penny I spent. The author's writing style was very accessible to the amateur historian. I also tried to read Seven Pillars of Wisdom several years agoe and had difficulty getting past the writing style, but will go back and read it again. This book opens the reader's eyes to many of the inaccurancies that surround the life of T.E. Lawrence and his relationships with his family and friends. I highly recommend this book.
Didn't want the book to end. Easily readable description of a fascinating man. Excellent handling of other biographers' viewpoints. Makes me want to read Seven Pillars of Wisdom by "Lawrence."
The lengthy story, for that is what Hero ls, leaves me unsure of how much is factual and how much is fiction, Some details relate accurately to other reading information which helps to substatiate the basis for the story, I would recommend Hero as one part of a more extensive historical biographical reading program, Limey


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Dr. Richard Wolin MD Patient Reviews
- Psychiatry Buffalo, NY
Overall Rating
8 Patient Reviews
- Wait Time 20 minutes
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Showing 1 - 8 reviews
1.0 of 5
May 12th, 2013
Stay far away
I had a terrible experience with this so-called "physician". I was mis-diagnosed after a brief "questionnaire" with a serious mental illness that I did not have (later properly tested and found out I was on the autism spectrum) and subsequently over-medicated. His idea of practicing "medicine" is to prescribe one med and then chase all the side effects with other medications. At one time he was routinely sending patients to a therapist named Barbara Booth and for some strange reason Dr. Wolin is the only psychiatrist that Barbara will work with. She lost her credentials due to unethical treatment and inappropriate relations with patients and yet Wolin "highly recommended" her. Wolin was always looking for reasons to "dismiss" me as a patient and when I finally left his practice and was taken off the medications we discovered they had done permanent, lasting damage. I wouldn't recommend this physician to anyone. You have zero say in your treatment and if you attempt to advocate for yourself, he threatens to drop you as a patient and tells you it's for your "own good" that you do things his way. As an aside, his lazy eye is awkwardly annoying too,
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June 26th, 2015
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1.0 of 5
October 30th, 2014
1.0 of 5
October 7th, 2014
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re DH's new job?(29 Posts)
Salient points:-
1. I earn significantly more than DH, although we largely regard our finances as joint family finances.
2. We could afford for DH not to work, but until recently he has always wanted to work which has been fine by me. We have used nannies for childcare (the most recent one was with us for 5 years).
3. DH decided he did not like his job. There was nothing awful about it, he just got a bit bored of it and there were one or two aspects which he did not enjoy.
4. DH decided to give up work. My earnings enabled him to do this. We made our nanny redundant, and the plan was that DH would essentially be a SAHP and we felt there would be lots of benefits to this from the DC's perspective for various reasons. Because the DC are school age, he lined up some part time charity work which uses his skill set so that he would not get bored, would have some adult interaction and would maintain his CV. So he is happy (as he got to give up a job he did not enjoy), DC are happy as DH is around more and able to help with homework etc (they were intiially a little upset about our nanny going so we did need to "sell" the plan a bit, but it has been working well and they have been enjoying having him around), and I am happy, in part becuase the DC are happy and in part because DH can do chores during the week that we would in the past have had to share at weekends.
5. A couple of months on, DH has found a new (full time) job. To be fair, he was not particularly looking for it, it just came up. It pays significantly less than the job he gave up (and I think will barely cover childcare costs). He has accepted it without much discussion. He has not done very much about sorting childcare, and seems to expect me to sort that out. He starts in 2 weeks. DC are cross that we made our old nanny (who they loved) redundant and are now talking about a new nanny (there is after-school club at their school, but they have a number of after-school activities that cannot easily be moved to the weekend, at least until the start of next term, and DD1 is talented in one of the activities so will not want to simply drop it for the rest of the term.)
So AIBU to be annoyed? There are a couple of different aspects that I am annoyed about, and I am sure at least some are reasonable (eg lack of discussion). However, I do wonder how it would be perceived if roles were reversed and he was a SAHM who had found a job.
Yanbu to be irritated with him. Your nanny lost her job for nothing! The children just got used to a new routine & now he is taking a job with little regard for you.
Whilst there is no point him being at home if he hates it,you decided all the prior changes together & so for that he is unreasonable.
I agree YANBU. The issue really isn't jobs per se, or feelings per se, or the sex of the individual concerned, but about communication, mutual discussion and mutual agreement about what's best for your family going forward. Any decision which affects a family practically, emotionally and financially should certainly be discussed before any final steps are taken - not least because one person on their own can't always imagine the potential pitfalls (or, in some cases, selfishly chooses to ignore them). It's not right that anything which affects other people adversely should be presented as a fait accompli.
Yes, it sounds as though your particular household can bear the overall drop in income as a result of this but to steam ahead and arrange this without speaking to you first - i.e. prewarning you - is selfish. Unless you're impossibly well off that drop in income will have an effect somewhere down the line - even if your day to day living standards don't alter, I assume you'd have less to put into savings for example and therefore your security is compromised. I fully accept that sometimes you have to adopt a no pain, no gain approach if in the future the end result is better in some respect (e.g. potential future earnings, better CV, better mental health etc) but that's something which you should both buy into. And yes, it's a damn cheek to lump the childcare issue on you .... you may well have organised this in the past and might well have been "good at it" but how very presumptious to assume you'll sort out the issue now which he's caused without any prior consultation!
I'm afraid I can't help feel he's been selfish and would also think the same of a woman doing the same thing. I appreciate he wants this job for all sorts of reasons but when you're in a family you really do have to consider the overall effect of what you want vs what the family needs and sometimes, it's not quite so simple as fulfilling yourself is it ? Dare I say he's had a pretty easy time of it so far - not many people are fortunate enough to be able to give up a job they hate, let alone one which wasn't out and out awful - and I do think he's taken you - and I guess the children too rather for granted. In other words, I really don't think he's sat down and thought about this objectively and has instead perhaps been carried away with the excitement of a decent sounding job that he actually didn't have to (by the sounds of it) put too much effort into finding - which is a position very few people are lucky enough to find themselves in these days. I'm not sure he's thought much about the children - what does he intend to do, for example, about re-organising activities and/or dealing with upset if and when stuff is dropped ? I'm saying BTW that kids have a god given right to certain activities - but if they're disrupted without a second thought, and the reason for that disruption wasn't necessarily vital then I do think he's been selfish.
You're in a difficult position because it seems a done deal and obviously you can't demand he rejects the job. What you can do though is insist he organises childcare asap and thoroughly so the kids are placed in the most suitable care (rather than - necessarily - the 1st childminder he finds) and he must also promise that before doing anything drastic again he must speak to you so you are equally informed about what's happening and also get a chance to voice your opinion.
Thanks everyone. To be fair to DH, there are I think 2 other reasons why he may think I shoudl take more of a role in sorting out the childcare. First, he feels guilty that he wont now be able to take on the role of the charity, so he is doing what he can for them this week during school hours, which reduces the time he has. Second, we had started to talk about changing our childcare anyway - we are paying for more hours than we need to have the backup during school hols and sicknesses and the older the children get the more of a luxury that seems (plus we were starting to have a couple of niggles with our nanny not really adapting as they get older, eg not really helping with homework or adjusting their routine - still often already in pjs when we get home etc). Against that, it is a luxury we could afford and gives the DC a lot of stability and flexibility, so I am not sure what we would ultimately have decided and in any event the timing would have been different (maybe looking for something different in Sept, which would also have been better timing for our nanny). Also to be fair to him he is not usually flaky.
I am going to tell him that he needs to sort the childcare, but am going to suggest the following:-
1. We use after-school club until the end of term in July for the 3 days when they dont have activities (or have acitvities we have not paid up for in advance and they wont mind missing). For the other 2 days, he should sort out a temp nanny.
2. We get a holiday nanny or an au pair to cover the summer.
3. We then look for permanent childcare from Sept - by then he should be able to go on to flexible working in his new job and should know what hours he is doing.
Your husband is making unilateral decisions which are detrimentally affecting everyone else in the family.
He should have discussed the new job with you.
He needs to arrange new childcare.
I would help where I can obviously as it is for the benefit of the family but he needs to take ownership of it and do the lion's share of the legwork.
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All the important stuff those of us in Australia and New Zealand need to know about the new Nintendo 3DS XL. Price, dates, colours and bundles.
{loadposition mike08}First up, a big sigh of relief, here in Australia and NZ the newly announced Nintendo 3DS XL will arrive in all three proposed colour schemes. No more making do with a limited palette to choose from down under.
Ok, the pricing still seems steep compared to our overseas buddies, but that���s all part of the deal with living in the best part of the world. Here are the local details for the launch of the 3DS XL:
2012 ��� A big year for the Nintendo 3DS��� system is about to get even bigger. In a Nintendo Direct video on June 22nd, Nintendo revealed plans to launch Nintendo 3DS��� XL, a new version of Nintendo 3DS with 90 percent larger screens. When it becomes available in Australia and New Zealand on August 23rd at the suggested retail price of $249.95*, the new system will create even more immersive entertainment experiences for users, delivering a wealth of games and video content that can be enjoyed on the go.
Nintendo 3DS XL features an updated form factor and will be available in Silver + Black, Red + Black, and Blue + Black. The new system���s battery life outperforms that of the original Nintendo 3DS, and it comes bundled with a 4GB SD card, which owners can use to store content such as downloadable games and videos from the Nintendo eShop. With upcoming titles such as New Super Mario Bros.��� 2 (launching 18th August) being available as digital downloads as well as boxed retail games, you will be glad of the extra space.
Nintendo 3DS XL launches on 23rd August alongside New Art Academy���, a new entry in the Art Academy series. The larger screens of Nintendo 3DS XL mean users will have even more room to unleash their creativity while enjoying art lessons that teach real-world drawing and painting techniques.
To view the latest Nintendo Direct video which contains more news on upcoming Nintendo products, visit www.nintendo.co.uk/
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What is memory address?
Memory address of an "object" is the location in RAM where that "object" starts. The "object" could be a piece of data, or a program. The "object" also has a length (in bytes), which means that the...
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What Is a Memory Address?
In relation to computers, a memory address is a numerical value that references a single element of datum inside of a storage medium. The location of computer memory could be inside the random acce...
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How to Delete an Incorrect Email Address From iPhone Memory?
When you create a contact on an iPhone, you're given the opportunity to assign them various phone numbers as well as an e-mail address. Should you put in the wrong e-mail address, or should they ch...
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What is the difference between "generic memory" and "proprietary memory"?
Hello,(ANS) No.1 Proprietary Memory. This is maker or brand, or machine specific you cannot get this any were else, the system requires this. Nothing else will match the machine and run it well. (i...
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What is an IP address my pc says "invalid IP address" when i try toconnect wirelessly to other pc?
Internet Provider...