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text: 4. As of noon trading, BB&T ( BBT) is down $0.18 (-0.6%) to $28.66 on light volume Thus far, 1.6 million shares of BB&T exchanged hands as compared to its average daily volume of 5.0 million shares. The stock has ranged in price between $28.56-$28.91 after having opened the day at $28.88 as compared to the previous trading day's close of $28.84. BB&T Corporation operates as a financial holding company for Branch Banking and Trust Company that provides various banking and trust services for retail and commercial clients. BB&T has a market cap of $19.9 billion and is part of the banking industry. The company has a P/E ratio of 11.2, below the S&P 500 P/E ratio of 17.7. Shares are up 13.1% year to date as of the close of trading on Wednesday. Currently there are 9 analysts that rate BB&T a buy, 1 analyst rates it a sell, and 18 rate it a hold. TheStreet Ratings rates BB&T as a buy. The company's strengths can be seen in multiple areas, such as its solid stock price performance, impressive record of earnings per share growth, compelling growth in net income, revenue growth and expanding profit margins. We feel these strengths outweigh the fact that the company shows weak operating cash flow. Get the full BB&T Ratings Report now. EXCLUSIVE OFFER: Jim Cramer's Protégé, Dave Peltier, only buys Stocks Under $10 that he thinks could potentially double. See what he's trading today with a 14-day FREE pass

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Nemaris is the wife of a soldier in Gareth Bryne's army.
After learning that Egwene al'Vere had been captured by the White Tower, Siuan Sanche needed a horse to quickly inform the Rebel Aes Sedai. Nemaris' husband lets Siuan use Nightlily, who is a mild horse but not as mild as Bela.[1]


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Test your knowledge of the U.S. manufacturing industry.
CFO Staff, CFO Magazine
November 1, 2010
On its own, this is a meaningless number. It also implies that the benefits of union membership are minimal. However, as Jim says, there are other things of value employees receive besides a paycheck. How does union membership affect benefits? Hours? Working conditions? And, do certain industries have higher or lower union membership? Is this an apples to apples comparison? I'm not a union member, but this single number taken out of context isn't very illuminating.
Posted by Marcelle Green | December 02, 2010 10:49 am
"Statistics never lie and only liars use statistics" Looking at question #8, it shows a minimal disparity between union and non-union wages. What this doesn't tell us is what makes up this number. For example, does it include the entire cost of support, including pension costs, health care costs, training, other benefits, etc. I would bet that there is a larger disparity in wages when everything is added up.
Posted by Jim Zapapas | November 30, 2010 02:37 pm© CFO Publishing Corporation 2009. All rights reserved.


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[Plugin: WordPress Connect] Shared Links directing to 404 page
I have recently installed WordPress Connect on wp 3.4.1
I also have WP Facebook Open Graph Protocol installed as well as SEO Ultimate. The problem is that when i share a post or page on fb, twitter, etc, the link returns to a 404 page.
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Your browser does not support iframes.
On Saturday afternoon the Roane State men's basketball team put together a sharp offensive outing at Cleveland State that allowed them to control the tempo of the game from start to finish.
Paul Kamikawa's Rockwood Tigers were on a mission Wednesday night to leave no doubt as to who was the best team in District 3-A, and Kamikawa's squad did just that with an impressive 54-43 victory over Tellico Plains in the District 3-A Tournament title game played at Rockwood's Dr. Tom W. Evans Gymnasium.
Second Lady Dr. Jill Biden visited the Harriman Technology Center Thursday afternoon along with the Secretary of Labor on their three-day "Community College to Career" bus tour. Please check Monday's issuse of the Roane County News for more information.
The Blair community is supposed to have an ISO evaluation.
When that will happen is Blair Volunteer Fire Department Chief Clarence Nelson's big question.
"In 2011, I went up to the fire hall three times waiting for you guys to show up, and you never did show," Nelson told Roane County Office of Emergency Services Director Howie Rose last week.
Rose said they sent a request to ISO and did not hear back.
Nelson said someone from Rose's office was supposed to go and check Blair's equipment.
Rockwood officials are investigating several questionable credit card purchases after putting Public Works Director Tom Pierce on leave last week, but one thinks the audit needs more expertise.
Councilman Jason Jolly thinks the city should look into having someone with more of a financial background take over.
Jill Biden, the wife of Vice President Joe Biden, will join with U.S. Labor Secretary Hilda Solis to make a stop in Harriman Thursday as part of a bus tour focusing industry partnerships with community colleges.
The tour, called Community College to Career runs from Feb. 22-24 and include stops in Ohio, Kentucky, Tennessee, Virginia and North Carolina.
Biden and Solis will talk about Roane State Community College's industry partnerships at an event at Tennessee Technology Center at 1:45 p.m. Thursday.
A Cleveland, Tenn., man was placed on probation for two years and ordered to serve 100 hours of community service for falsifying work records at the TVA's Watts Bar Nuclear Plant.
John Delk, 40, pleaded guilty last November.
A federal judge sentenced him on Feb. 16.
A 39-year-old man was charged with promotion of methamphetamine on Feb. 16.
According to a Roane County Sheriff's Office report, Shane Ellis Wyatt was a passenger in a car that was stopped on Hwy. 72 because the driver, Reggie Davidson, had an active warrant.
"In Mr. Davidson's vehicle I found a black bottle with a bag of white powder inside believed to be methamphetamine," the report said.
The report said the officer also found two small hoses, duct tape and a bottle of brake fluid.
By Ellen Probert Williamson
The beginning of Lent, Ash Wednesday, falls on Feb. 22 this year.
Churches across the country observe this day with special services that usually culminate with the marking of a cross with ashes on the foreheads of the faithful.
The ashes used for these ceremonies of devotion are traditionally those resulting from the burning of palms left from the previous year's Palm Sunday observance.
Copyright © 2017
The Roane County News is your source for local news, sports, events, and information in Roane County and Kingston, Tennessee, and the surrounding area.


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This isn't goodbye but it's a pretty big change. So, here it goes –
We'll stop selling gear on September 9th.
Words I've dreaded having to say. There is good news though –
But we're not going away.
Let me explain.
Over 11 years ago I took a love of outdoor gear and passion for camping with my Lab, Huron, mixed it with my technical knowledge and a desire to provide customer service that would rival companies like REI. Backcountry K-9 was born. In that time we've helped tens of thousands of customers outfit their dogs for outdoor adventures. Not too bad for a small business with one employee.
In that same time though, giants like Amazon have grown to dominate the e-commerce market. The same Amazon that leased 20 more cargo planes this year to further facilitate their own logistics. The same one that now offers same day delivery in more than two dozen markets across the US.
These are good things for consumers. These are the big ideas that drive e-commerce forward. Unfortunately, little guys like us don't always have the resources to continue to compete with these giants. It's sometimes unfortunate but it's progress.
So, I'm bringing the business back to it's roots – my love for technical gear and outdoor adventures with my dogs. We'll renew our commitment to share our expertise and passion with you through new and additional content. Whether it is learning about new gear, getting expert advice on fitting and using a backpack for your dog, downloading a pack list for your upcoming backpacking trip, or learning about getting into a new sport with your dog, like skijoring, we'll strive to be your virtual guide. We'll continue to showcase gear, expand our blog and foster our social communities across Instagram, Facebook, and Twitter.
I'm excited for this new direction. I'm excited to remain engaged with manufacturers bringing their new gear to the market. Excited to hear of and see your adventures with your dogs.
From now through September 9th, head over to our store to find great gear on sale like EzyDog, Hurtta, Mountainsmith, D-fa, Kurgo and more. During this time our Ruffwear gear will not be on sale but we will have full stock thanks to our close partnership with them.
After September 9th, our online store will closed but stop by for a look around. We'll be showcasing all the best gear, showing you where to buy it, how to use it and sprinkling in our expert advice.
Need help with a return during our closeout sale? No problem. Our regular return policy applies but we will be shortening the return window from 60 days to 30 days starting July 22nd.
In need of warranty help? Again, no problem. We're not going away and are in good standing with all of our manufacturers. We'll be able to facilitate any warranty claims no matter when they come up. We continue to stand by anything you bought from us.
I hope you'll join us for this next adventure.
Happy Trails!
Backcountry K-9


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Interferon-Induced Gene Expression in Liver Cells and Peripheral Blood Lymphocytes
This study has been completed.
National Institute of Allergy and Infectious Diseases (NIAID)
Information provided by:
National Institute of Allergy and Infectious Diseases (NIAID)
ClinicalTrials.gov Identifier:
First received: May 9, 2006
Last updated: August 26, 2010
Last verified: April 2009
- Full Text View
- Tabular View
- No Study Results Posted
- Disclaimer
- How to Read a Study Record
Detailed Description:
This proposal seeks to use DNA analyses to understand how racial and genetic factors influence interferon (treatment) response in HCV infection in African Americans. A better understanding should allow rational design of new therapies or better use of existing therapies. Patients will provide medical history and undergo a physical exam, blood draws, electrocardiogram, possible chest x-ray, and abdominal ultrasound. Patients will be admitted to the hospital for 5 days and undergo 2 liver biopsies, sedation, and multiple blood draws. Twenty adult male volunteers (10 Caucasians,10 African Americans) ages 18 - 65 years will participate.
|Hepatitis C
|Drug: Interferon alpha
|Phase 2
|Study Type:
|Study Design:
|Allocation: Non-Randomized
Intervention Model: Single Group Assignment
Masking: Open Label
Primary Purpose: Treatment
|Official Title:
|A Pilot Study to Characterize Interferon-Induced Gene Expression in Liver Cells and Peripheral Blood Lymphocytes Using High Density Oligonucleotide Microarray Expression Analysis in Caucasian and African American Patients With Chronic Hepatitis C
Resource links provided by NLM:
MedlinePlus related topics: African American Health Genes and Gene Therapy Hepatitis Hepatitis A Hepatitis C
Drug Information available for: InterferonU.S. FDA Resources
Further study details as provided by National Institute of Allergy and Infectious Diseases (NIAID):
|Estimated Enrollment:
|Study Start Date:
|May 2006
|Estimated Study Completion Date:
|June 2006
This proposal uses sophisticated DNA microarray analyses of the transcriptional changes induced in hepatocytes (cellular locus of viral replication) and peripheral blood lymphocytes (one compartment of immune responder cells) in an effort to better understand how racial and host genetic factors influence interferon response in HCV infection. A better understanding of these underlying mechanisms should allow rational design of new therapies or better use of existing therapeutic modalities. The variables to be investigated are racial differences in interferon induced: 1) HCV viral kinetics and 2) intrahepatic and PBL transcriptional responses. Specific Aim 1: (a) To compare the phase 1 and early phase 2 decline of the viral titer in serum in African-Americans and Caucasians following a single dose of IFN-alpha (10 MU sc). (b) To determine the hepatic HCV RNA abundance in both a baseline liver biopsy and in a repeat liver biopsy taken 24 hrs after administration of interferon, and to determine how this correlates with the HCV RNA decline in serum over the 24 hr period. (c) To compare the rates of viral decline in the liver and serum in African-Americans and Caucasians 24 hours after interferon, and to relate this to the pharmacokinetics (PK) of the initial dose of interferon. A total of 10 Caucasian and 10 African American patients with chronic hepatitis C and HCV genotype 1 will be enrolled in this study. All study patients will undergo a baseline percutaneous liver biopsy on day 1 of the study. On day 3, a single dose of IFN-alpha 2a (10 MU sc) will be administered and a repeat liver biopsy will be done 24 hours after the injection. Specific Aim 2: (a) To utilize Affymetrix HG-U133A&B Human GeneChips® to determine global mRNA profiles in liver tissue collected from patients before and 24 hrs after a single 10 MU dose of IFN-alpha and thereby assess the intrahepatic transcriptional response to IFN-alpha. (b) To characterize differences in the early intrahepatic transcriptional response to interferon in Caucasians and African Americans. Specific Aim 3: (a) To utilize Affymetrix HG-U133A&B Human GeneChips® to determine global transcription profiles in peripheral blood lymphocytes pre-treatment, 24hrs, and 48hrs after the initial dose of interferon and to compare these results in Caucasians and African Americans at these time points. (b) To compare global gene profiles in lymphocytes and liver at baseline and 24hrs after interferon, and determine whether lymphocytic transcriptional profiling is a valid surrogate for intrahepatic gene profiling. Specific Aim 4: To use sophisticated bioinformatics approaches and HCV kinetic modeling to determine whether differences in early intrahepatic or lymphocytic transcriptional profiles correlate with early changes in the level of viremia (observed antiviral response) in the period immediately following administration of the 10 MU dose of IFN-alpha.
|Ages Eligible for Study:
|18 Years to 65 Years (Adult)
|Sexes Eligible for Study:
|Accepts Healthy Volunteers:
Inclusion Criteria:
- Male non-Hispanic African-American or non-Hispanic Caucasian patients between 18 and 65 years of age
- Abstinence from any ingestion of alcohol and smoking for at least 7 days prior to study for those who drink or smoke socially
- HCV genotype 1 (1a, 1b or mixture of 1a and 1b). HCV genotyping will be performed at the Molecular Diagnostic Laboratory at UTMB using the LiPA assay (Innogenetics)
- Presence of HCV RNA in serum (>10 [to the fifth power] copies/ml)
- Not previously treated with any interferon and/ or ribavirin
Compensated liver disease with the following laboratory criteria:
- Hemoglobin greater than or equal to 13 gm/dl for males
- Granulocyte count greater than or equal to 1,000/cubic mm
- Platelets greater than or equal to 100,000/cubic mm
- Prothrombin time <2 sec. elevation
- Total bilirubin (0.1-1.1 mg/dl). If elevated, the conjugated Bilirubin must be within normal limits (0-0.3 mg/dl)
- Serum albumin within normal limits (3.5-5.0 g/dl)
- Serum creatinine within normal limits (0.7-1.7 mg/ml)
- Absence of other known causes of liver disease (e.g. autoimmune hepatitis, hemochromatosis, Wilson's diseases, alpha-1 anti-trypsin deficiency, drug-induced liver injury, alcoholic liver disease)
- No other systemic antiviral or immunosuppressive therapy within the last 6 months
- Absence of concurrent medical and psychiatric illnesses (e.g. other viral co-infection such as HBV or HIV, renal failure, poorly controlled diabetes, cardiac-pulmonary diseases, CNS disease, active alcoholism, depression, psychosis)
- No history of Type 1 or Type 2 diabetes mellitis
- TSH within normal limits (0.49-4.7 micro IU/ml)
- No history of hepatocellular carcinoma
- Alpha fetoprotein within normal limits (0-20 ng/ml) obtained within 6 months of enrollment.
- If participating in sexual activity that could lead to pregnancy, the study volunteer must agree that two reliable methods of contraception will be used with his partner simultaneously while receiving medication, and for 6 months after stopping the medications. The following are considered reliable and effective methods of birth control.
1) Condoms with or without a spermicidal agent 2) Diaphragm or cervical cap with spermicide 3) IUD 4) Hormonal-based contraception 16. Exceptions may include if study participant/partner is surgically sterile 17. Willingness to comply with procedures and treatment as outlined in the protocols and provide written informed consent
Exclusion Criteria:
- Interferon or ribavirin therapy at any previous time
- Any investigational drug <= 24 weeks prior to the first dose of study drug
- Any alternative or folk medicine within 24 weeks of screening
- Any systemic antiviral therapy <= 24 weeks prior to the first dose of study drug or expectation that such treatment will be needed at any time during the study. Exception: patients who have taken or are expected to require acyclovir for herpetic lesions
- Patient with a baseline increased risk for anemia (e.g. hemoglobinopathies such as thalassemia, spherocytosis, sickle cell anemia or a history of symptomatic recurring GI bleeding, etc.) or for whom anemia would be medically problematic
- Evidence of alcohol and/or drug abuse within 6 months
- History of immunologically mediated disease (e.g., inflammatory bowel disease, idiopathic thrombocytopenic purpura, lupus erythematosus, autoimmune hemolytic anemia, scleroderma, severe psoriasis, clinical evidence of rheumatoid arthritis)
- Evidence of an active or suspected cancer or a history of malignancy
- History of having received any systemic anti-neoplastic or immunomodulatory treatment (including supraphysiologic doses of steroids and radiation) <= 6 months prior to the first dose of study drug or the expectation that such treatment will be needed at any time during the study
- History of major organ transplantation with an existing functional graft
- History of bone marrow transplantation
- Anything that in the opinion of the investigator puts the patient at increased risk, or increases the likelihood that the patient may not be able to complete the protocol
Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.
Please refer to this study by its ClinicalTrials.gov identifier: NCT00324389
Please refer to this study by its ClinicalTrials.gov identifier: NCT00324389
|United States, Texas
|The University of Texas Medical Branch
|Galveston, Texas, United States, 77555
Sponsors and Collaborators
National Institute of Allergy and Infectious Diseases (NIAID)
More Information
Keywords provided by National Institute of Allergy and Infectious Diseases (NIAID):
Additional relevant MeSH terms:
ClinicalTrials.gov processed this record on July 25, 2017
|ClinicalTrials.gov Identifier:
|NCT00324389 History of Changes
|Other Study ID Numbers:
|Study First Received:
|May 9, 2006
|Last Updated:
|August 26, 2010
Keywords provided by National Institute of Allergy and Infectious Diseases (NIAID):
Interferon, Gene Expression in Liver, Lymphocytes, High Density Oligonucleotide Microarray Expression Analysis, African American, Hepatitis C
Additional relevant MeSH terms:
Hepatitis A
Hepatitis C
Liver Diseases
Digestive System Diseases
Hepatitis, Viral, Human
Virus Diseases
Enterovirus Infections
Picornaviridae Infections
RNA Virus Infections
Flaviviridae Infections
Antineoplastic Agents
Antiviral Agents
Anti-Infective Agents
Immunologic Factors
Physiological Effects of Drugs
ClinicalTrials.gov processed this record on July 25, 2017


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It's a crazy time to be a One Piece fan (Japanese or otherwise). With his first big enemy and public display down, Luffy has cemented himself as a big player in a big game. And for the first time in OP history, we know who just about all the big players in the game are. We've reached a sort of peak of knowledge. Many people we've been waiting to see since the timeskip have shown up, we've been introduced to parts of the crews of the Yonko, and we've seen the new Shichibukai. The list of people that we don't know is getting smaller when you look at the big players.
And with this game, everyone has their targets, and Oda has actually told us who they are.
So this blog is here to make a list of who's gunning for who, etc.
- Shanks
- Shanks has yet to be seen post-TS and he's never been known to be the kind of person that is after someone. But we do know one thing: The Kid/Hawkins/Apoo alliance is after his head.
- Kid/Hawkins/Apoo
- Even though their target is Shanks they were last seen standing in front of a very pissed off Yonko, and 2 out of the 4 Supernovas present looked scarred shitless (Kid just looked pissed, and nobody knows what Killer's face looks like).
- Big Mom was also known to be pissed at Kid for destroying some of her ships.
- Big Mom
- She's already in a feud with Luffy over Fishman Island, and recently her crew had a showdown with the "Team Swirly Brow" part of the Straw Hats.
- This fight was over Caesar Clown, and it sounds as though she sent her subordinate crew, led by Supernova Capone Bege to get him. This incident happened several days after the battle on Dressrosa, and the Sunny confrontation.
- Caesar Clown
- Poor guy, he's in the custody of the Straw Hats, but he has people from Doflamingo's, Kaido's, and Big Mom's organizations after him. Plus a hefty 300 Million bounty on his head to boot.
- Donquixote Doflamingo
- Recently defeated by Luffy/Law and in the custody of the Marines.
- However, Kaido seems to want him anyways, and sent his guy Jack to go get him from a 4 ship fleet (which includes some Admirals, former Admirals and some Vice Admirals).
- He's also a hot commodity among his former clients, which all want their weapons shipments.
- Fujitora
- He pissed off Akainu, and now it seems once he's done with carting Doffy around, he's going to be after Law and Luffy. He gave them their "get out of jail free card" already, and now it seems he's going to be serious about arresting them. After all, Tsuru's die roll demands it.
- The Samurai of Wano
- At this point in time, we don't know why they left for Zou. However we do know a few things: They know who Kaido is, and Kaido has a presence on Zou. Doffy made the capture of Momonosuke a priority, despite the fact that their presence on PH and Dressrosa was purely accidental. It seems odd to me that any kind of mission outside of the country would include bringing along 2 Samurai, 1 ninja, and a small child. There's something special about the boy, and I think Kaido has something to do with it.
- Kaido
- He just seems pissed at the world, and wants to start the largest war yet.
- In particular though, he's after Doffy for the supplies for it, including weapons and SMILES for his Zoan army.
- The Law/Luffy alliance is obviously after him, though it remains to be seen how pissed he is at them directly, so far his anger has only been towards Doffy.
- The Revolutionary Army
- Prepare for obvious statement: The Revolutionaries are after the World Government.
- However, their main focus right now is weapons. Specifically, the flow of weapons from an unknown source. They were after the weapons on Dressrosa before they knew of Luffy or the Mera Mera no Mi being there. Weapons were always their main focus, other things just got in the way.
- Getting their hands on these weapons was important enough for Dragon to call the leaders together for an in-person meeting. That shows just how much they matter.
- Burgess is willing to ask the entire Blackbeard Pirates organization to go there just to get him and the weapons.
- Unknown Weapons Manufacturer
- The only organization on the list we know almost nothing about. However, with recent chapters, it's clear they have a part to play in the future of the world..
- The revolutionaries are almost certainly after them. They got the dealer, but now they want the whole operation.
- And just about anyone that wants to start conflicts would probably like to get their hands on the manufacturer too.
- They're also after the collection of weapons, in addition to whatever goals they have as a World Government agency. Also, if all the former members of CP-9 are in CP-0, this organization is quite large.
- Blackbeard
- He's after the Revolutionaries now it seems, in addition to his quest to gather powerful Devil Fruits. The entire series, Blackbeard has done nothing that was not for a specific goal, all of which ultimately lead to him becoming more powerful. He's up to something for sure, and he's getting closer to his endgame.
- I'd be terrible if I didn't mention his recent talks/apparent alliance with Kuzan as well.
- Edward Weeble
- The newest Shichibukai, he's (or rather his mother) is after the remnants of the Whitebeard Pirates.
- This includes a recent plan to beat up Luffy and ask him where Marco is. We'll see how that goes...
- Weeble's one desire for himself though is vengence on Blackbeard for killing his supposed "father". And if he gets angry and powerful enough to fight a crew of New World pirates and destroy a town killing 600 just over someone saying he's not WB's true son, then what he'd do to Blackbeard is likely insane.
- Buggy
- He's after money, as always. But apparently the resignation of Harujidin is gonna cost him a bunch of money. Is that enough to send him after Luffy once again? Maybe...
Straw Hats/Law
A bunch of people are after them:
- Marines
- Specifically Issho
- Big Mom and underlings
- Specifically Capone Bege, who wants Caesar
- Kaido and underlings
- Buggy and underlings
- Edward Weeble/Bakkin
- He's not directly after him, but there's bad blood between Luffy and Blackbeard.
- Oh yeah, there's also the matter of the crew's total bounty of 1,570,000,100, plus Law's 500,000,000, AND Caesar's 300,000,000. If you can take them out, boy are you gonna be rich!
So yeah, that's all I've got for now. But you can see by the shear size of it, there's quite the web building of people gunning for each other. There sure are a lot of Targets out there! (I said the title of the blog in the blog! Oh man, I'm so good at this!) JustSomeDude... Talk |


text:
Use the Chronoscope Hamburg for a time-warp into the history of Hamburg. Dive and navigate through old maps and see how the city has changed since 1694. Activate the Chronoscope now.
Design and development by mprove.
As a florists once told me, "Somebody who cannot say no – is unable to stick to a yes." /photo
Attending the rehearsal of ensemble reflektor playing Beethoven's 3rd. //photo credits
aufmerksam für das gewöhnliche – aufmerksam für die innovation was a workshop we conducted at World Usability Day. Subtitle: interaction & service design meets scenography. See photos and slides on UX journey mapping the event.
My best 42 minutes in 2015 have been the live concert at Raum Schiff Erde. 'Then my feet leave the ground, hands holding on to a ballon....' by Lunartree. See and listen_ http://raumschiffer.de/media/2015/lunartree.html
17hrs left to support #freeyourdata at http://bit.ly/video-bomb To be launched on Monday noon, Mar-16 by http://freeyourdata.org & protonet.
Raum Schiff Erde is a unique congress for digital philosophy, interaction design, and net culture for people with a global mind-set. #RSE15 will launch in Hamburg on Feb-22, 2015 http://raumschiffer.de
Visit my social bookshelf here_ http://www.anobii.com/mprove/books
I love deadlines. I love the whooshing noise they make as they go by. – Jerome K. Jerome, 1889


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Super excited to get the dress. I'm wearing it for prom and I ordered a large instead of my actual size because I can get it taken in. You can't get it taken out. So if it fits, great! if not, it's not a huge deal. Can't wait to get it!
Romantic Plunging Neck Gauze Spliced Slit White Maxi Dress For Women
February-02/2016 07:01:03 Michelle Harrison
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Operation, Cleaning And Preventive Maintenance of the Machine.
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Description: Latin America has often been condemned to failure. Neither poor enough to evoke Africa's moral crusade, nor as explosively booming as India and China, it has largely been overlooked by the West. Yet this vast continent, home to half a billion people, the world's largest reserves of arable land, and 8.5 percent of global oil, is busily transforming its political and economic landscape. This book argues that rather than failing the test, Latin America's efforts to build fairer and more prosperous societies make it one of the world's most vigorous laboratories for capitalist democracy. In many countriesincluding Brazil, Chile and Mexicodemocratic leaders are laying the foundations for faster economic growth and more inclusive politics, as well as tackling deep-rooted problems of poverty, inequality, and social injustice. They face a new challenge from Hugo Chavez's oil-fuelled populism, and much is at stake. Failure will increase the flow of drugs and illegal immigrants to the United States and Europe, jeopardize stability in a region rich in oil and other strategic commodities, and threaten some of the world's most majestic natural environments. Drawing on Michael Reid's many years of reporting from inside Latin America's cities, presidential palaces, and shantytowns, the book provides a vivid, immediate, and informed account of a dynamic continent and its struggle to compete in a globalized world.
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Lifecycle Technology Items9 textbooks were found
The Usability Engineering Lifecycle: A Practitioner's Handbook for User Interface Design (Interactive Technologies)List Price:$98.95
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I had an open Rhinoplasty about 5 months ago. The overall look of my nose is okay except for the tip/columella area. I think my columella looks too wide and my tip a little round. My doctor refined my tip with sutures and added a graft for support in my columella. Is this attributing to my columella looking wider/fuller than before, and will it subside and shrink with time? I'm hoping my nose will soften up and get smaller in size. Any feedback or advice would be lovely.
Will Columella Fullness Subside with Time?
Doctor Answers 16
Columellar Fullness
Swelling may last longer after an open rhinoplasty with placement of a columellar graft. You understand the graft was placed to increase or maintain tip projection. It will be worth the wait. If your not satisfied with the with of the columella after healing is complete, revision is a relatively minor procedure under local anesthesia.
Tip or columella fullness after open rhinoplasty
It is usually best to wait between six months and a year before contemplating any revisions.
Revisions in this area are usually straightforward.
Patients must always be realistic, particularly with tip fullness and the overall size of the nose. Noses that were once very large will not usually look good if they are made excessively small.
Learn more: http://www.drbrent.com/index.php
Columellar thickening
Learn more: Http://www.DoctorMeade.com
You might also like...
Will Columella Fullness Subside with Time?
The tip will most likely come down with time as the swelling continues to improve. As for the width of the columella, it will depend on how wide the graft is. At 5 months you still have some time to go before your final results are evident.
Michel Siegel, MD
Houston, TX
Will columella fullness subside with time?
The fullness you are experiencing should improve with time. The tip/columella is the last area for the post-operative tissue swelling to resolve. It can take up to about a year to see the swelling return to normal.
Check with your surgeon to check to make sure everything is healing as anticipated otherwise.
Learn more: http://www.drlamperti.com/facial-plastic-surgery/rhinoplasty
Columella fullness after open rhinoplasty
Post operative swelling and stiffness for a rhinoplasty may take 6-12 months to resolve (or more). Since the nose is vertical on your face, the tip and columella will "collect" all the swelling for a longer time than at the top of your nose. The open approach to rhinoplasty severs the lymphatics of the columella and the lower part of the nose, sometimes causing a more prolonged swelling in this area. As these lymphatic connections "re-connect", you will start to see less swelling. Be patient, but also communicate with your surgeon. Certainly the tip work and grafting that he/she performed will contribute to your swelling.
A Columellar Strut May Increase The Width Of The Columella After Rhinoplasty
Fullness in the columella after rhinoplasty at 6 months after surgery can be a contributing factor. A columellar strut is placed between the medial footplates which make up some of the columellar width. This can increase its width by 1 or 2mms dependent upon the width of the graft. That combined with persistent swelling will definitely make the columella appear slightly wider. Despite the widespread use of columellar struts, increased columellar width is not reported as being a significant problem with its use. I would wait a full year after surgery so that every little bit of swelling is gone before making a final judgment.
Learn more: http://www.eppleyrhinoplasty.com/
Columella fullness after rhinoplasty
5 months after rhinoplasty the swelling of the columella should have subsided almost completely. Tip graft, columella graft may contribute to the residual swelling and may not resolve. Correction is possible but you should carefully consider this.
Rhinoplasty - columella thick
It's hard to know how much thinner your columella will get - it depends on how thick a piece of cartilage your surgeon used. However, I'd wait until about a year after your surgery before proceeding with revision surgery. I'd continue to see your surgeon, have him document changes with photos, and if you are still unhappy after a year, I'm sure he/she would be happy to revise it for you.
Dr. Cat Begovic M.D.
Learn more: http://www.makeyouperfect.com
Columella and width
Sometimes a columella strut can contribute to the columella width and certainly swelling can as well.
Learn more: http://www.stevenwallachmd.com
These answers are for educational purposes and should not be relied upon as a substitute for medical advice you may receive from your physician. If you have a medical emergency, please call 911. These answers do not constitute or initiate a patient/doctor relationship.


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McCall's 6840 A; ©1963; Misses' and Women's Suit and Overblouse. Back buttoned overblouse, slim three-gore skirt and single breasted jacket. Scooped neck blouse has unmounted short sleeves, vents in front dart seam. Dart fitted skirt has left side zipper, back pleat. Lined jacket has three-quarter length set-in sleeves, fake pocket welts. Neck and fronts of jacket and back edges of blouse are interfaced. Decorative stitching on jacket and blouse.
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Research engineer position: Web architect – JEE, Ruby/RoR – Semantic web technologies
Employer: University of Montpellier (ex UM2)
Context: SIFR project (Semantic Indexing of French Biomedical Data Resources) - ANR
When: January 2015 – for 12 months minimum eventually extensible of one year.
Where: LIRMM (collaboration with UMR TETIS (Cirad) and the NCBO (Stanford Univ.))
Web development, (biomedical)ontologies & terminologies, semantic web, biomedical data integration, semantic interoperability, linked data, scientific data workflows, annotation, text mining.
Web development, Java/JEE, Ruby/Rails, MySQL, RESTful web services, XML/JSON, Web client technologies (HTML5, JavaScript, CSS, Ajax), Semantic Web technologies (OWL, RDF, SPARQL, 4store, Linked data), NCBO technologies (BioPortal).
The SIFR project (http://www.lirmm.fr/sifr/) investigates the scientific and technical challenges in building ontology-based services to leverage biomedical ontologies and terminologies in indexing, mining and retrieval of French biomedical data. The project is mainly funded by the French ANR, the University of Montpellier, the CNRS and the Montpellier Institute for Computational Biology (IBC).
We are seeking an experienced Web developer to take hands on the different prototypes developed within the project and to setup and support the project's platform of services. One main aspect will be the maintenance and integration of new services inside our local instance of BioPortal.
The volume of data in biomedicine is constantly increasing. Despite a large adoption of English in science, a significant quantity of these data uses the French language. The community has turned toward terminologies and ontologies to design semantic indexes of data that leverage the medical knowledge for better information mining and retrieval. However, besides the existence of various English tools, there are considerably less ontologies available in French and there is a strong lack of related tools and services to exploit them. This lack does not match the huge amount of biomedical data produced in French, especially in the clinical world (e.g., electronic health records).
Within the SIFR project we build an ontology-based indexing workflow similar to what exists for English resources (e.g., NCBO Annotator) but dedicated and specialized for French and make it available as a service for the community. We will use this workflow for semantic indexing of French biomedical data. We also develop such a workflow for bioontologies (English) related to plants within the WP5 of the IBC project.
We investigate issues related to multilingual knowledge representation (alignments between multilingual ontologies) and maintenance/evolution of created annotations and mappings over time. Especially, the use of the multilingual (French-English) mappings will enable us to index French resources using English ontologies and to search English resources, already indexed with English ontologies. We envision potential interesting result in semantic search and automatic translation. We will also investigate the process of lifting the annotated data in the web of linked data.
We are reusing the technologies developed by the National Center for Biomedical Ontologies: (https://github.com/ncbo): the BioPortal Web application (http://bioportal.bioontology.org) and the BioPortal service architecture (http://data.bioontology.org/documentation).
The developer will have:
- to manage, administrate and modify a local instance of BioPortal (as described http://www.bioontology.org/wiki/index.php/Category:NCBO_Virtual_Appliance) both for the SIFR and IBC projects.
- to modify the data workflows in the platform to customize it for our project needs.
- to integrate new prototypes such as BioTex (http://tubo.lirmm.fr/biotex) within the platform.
- to implement new data workflows within the platform such as mapping extraction, plant linked data, semantic distances
- Web developer with good knowledge of JEE technologies (such as Spring) and Ruby/Ruby On rails.
- Experience with semantic Web technologies.
- Computer science engineer or master degree. PhD applicants are welcome and preferable if they can demonstrate a strong development experience and commitment.
- Between 2 and 5 years of experience. Including experience in private companies.
- Excellent technical skills to push prototypes into production environment.
- Interested by the Semantic Web field and cutting edge Web technologies.
- Perfect English oral and writing skills.
- Experience or few knowledge with French with objective to learn the language during the contract.
- Excellent writing skills as reports, documentations, and technical notes will always be necessary.
- International trips accepted (collaboration with Stanford) and possibility to get a visa for the USA.
- Autonomy and initiative, take on technical decisions within the project and justify choices.
- Friendly person to join a small research team in Montpellier and to listen to their needs.
- Eventually interested in research valorization of the outcomes (everything will be published).
- Open source developer.
For more information about this position, please contact Clement Jonquet (firstname.lastname@example.com). To apply, please send an email including links to (NO ATTACHED DOCUMENTS) the following:
- a motivation letter describing an explanation of YOUR interest for the position;
- a curriculum vitae describing your experience and the matches with the expected profile;
- copies of diplomas and other relevant certificates;
- names and contact details of referees.


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Will Resurging Microsoft Affect Apple?
- Microsoft's October 6th Keynote showed promise for the company's future.
- Rumors of an 'Apple Car' sent stock shooting up.
- Apple's acquisitions show that they are building for long-term growth.
On October 6th, 2015, Microsoft (NASDAQ:MSFT) showcased a range of devices running Windows 10 which drew the admiration of top journalists. The biggest takeaway from the event was Microsoft's ambition to stay ahead of competitors- something they have arguably failed to do in the past. Plus, we saw a Microsoft focused on both hardware and software. It is worth noting that as the Microsoft event went on, Apple (NASDAQ:AAPL) stock suffered a drop; however it has since bounced back strongly (more on that further down) With Windows 10 running devices likely to flood the market-where does that leave Apple and its investors?
Apple has such tight control of its entertainment delivery network that it is going to be challenging for Microsoft to compete on this level. Approximately 1 billion downloads have been registered on the Apple app store while the figure for the Windows app store isn't even close. Moreover, due to the fact that Windows is delivered to manufacturers with their own entertainment ecosystems, Microsoft is unlikely to ever have 'one app store to rule them all'.
Secondly, Apple continues to find ways to grow its ecosystem. For instance, Apple Pay is available in 375 banks, and there is a gradual global rollout. Apple Music was launched to compete with Spotify, and although it lags way behind, there is room for Apple to grow.
On the other hand, Microsoft's Xbox Music offering hasn't enjoyed the same market penetration.
Although Microsoft showcased an innovative virtual reality headset named 'Holo Lens', as is frequent with Microsoft prototypes we still don't know when it is going to be launched. Interestingly, they decided to showcase Holo Lens interacting with games. However, it was a big opportunity to endear the profitable science-and-tech-industry by showcasing solutions for them.
On the other hand, Apple hasn't given the world something, which causes us to reminisce about the buzz surrounding the first iPhone or the Macbook air in last few years. However, in the eyes of the everyday consumer, Apple still makes highly desirable products. For instance Apple sold 47.5 million iPhones in Q3 of 2015 alone, and 500+ million iPhones have been sold overall. And after record breaking sales by the iPhone 6s, Apple is gaining ground in the huge Chinese smartphone market.
Additionally, Elon Musk, Tesla Motors CEO, triggered a frenzy of rumors surrounding the 'Apple Car' by stating that Apple is hiring some of his engineers. This proclamation caused Apple's stock to shoot up 2.37%. Investors know that not only does this signal Apple's intention to enter the lucrative autos industry, but it may also signal an intention to be more than just a consumer tech company.
Plus, looking at the brand perception Apple enjoys, investors are almost certain that a car with an Apple logo could- if priced well- become the most sought-after vehicle on the planet.
Microsoft has a long list of acquisitions, a significant number of which we are yet to see being integrated into their products or services. It is worth noting that if Microsoft were to take their time to strategize, and integrate their acquisitions more, they would probably be a force to be reckoned with.
Apple has a considerably smaller set of acquisitions; however, they seem to be more carefully selected as compared to Microsoft. For instance, Apple acquired Beats in Q3 of 2014, and have already integrated it into Apple Music. Moreover, due to the youthful brand image of Beats, this acquisition is likely to be one of their wisest.
In conclusion, it can be argued that Microsoft's keynote earlier this month was highly impressive, and showed a strong intent not to get left behind. However, as is the case with a lot of Microsoft's product announcements, a considerable period of time passes before the product is up for sale. For example, Holo Lens was announced in January of 2015, yet developers are going to get their hands on it early next year; therefore, a release date is anyone's guess. This type of action reduces the buzz by the time the product finally launches, causing a necessity to spend a lot of moeny on advertising.
Apple has a strong brand image, and makes highly desirable products. And this is partly why their stock is likely to perform well in the longterm. Microsoft is resurging, and if its next keynotes are as well received as the one on October 6th, they would be a strong contender.


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Just one glass of cherry juice is loaded with antioxidants that provides a wealth of benefits, including reduced muscle soreness. Our Fleece Horse Blanket does double duty. Even if you've trained and prepared for running a long distance, your muscles may feel sore. The brave souls who endured an ice bath for at least five minutes after exercise reduced muscle soreness by 20 percent compared to those who simply rested [2]. Heat therapy can be dry or moist, and can be applied locally to a specific area in the body. 1.
The more time and effort you put into understanding your injury and tending to it, the quicker and stronger you will heal. ice debate. Heat and cold are the two most common types of relief therapies for muscle and joint pain. The most important aspect of heat therapy is its ability to increase blood flow to the painful areas. Alternate the days you focus on strength training, aiming for three days of strength training and three days of cardio. Do your stretches or exercises There is a reason you were told to do them.
Or, if you're sore all over, do a light workout on an elliptical machine or in the pool, suggests Jaime Edelstein, DScPT, CSCS, a physical therapist at the Hospital for Special Surgery in New York City. Both the lower and upper back can become sore during squats, as can the shoulders and upper arms since the arms are extended during the exercise. Ironically, this adaptation process produces greater stamina and strength in the muscles as they recover and build in growth and size (muscle hypertrophy). You'd think that with this impressive pile of studies we'd be closer to figuring out some sort of effective therapy for the symptoms, or better yet, some sort of preventative measures that would minimize or eliminate them. I've never given one as a gift that wasn't incredibly well received. Ice is a vasoconstrictor; it reduces the tissue's metabolic rate and reduces internal bleeding to the injured muscles, which reduces the overall effect of the injury and promotes a quicker recovery.
Massage therapy manipulates the ligaments, tendons and muscles through various pressing and rubbing techniques. If the pain is strong, it may even keep you from sleeping and leave you fatigued, too. I upped my weekly running mileage from between 5 and 7 miles to 12. Sure, we all know that warming up and cooling down is the way to prevent sore muscles, but what happens if your muscles are sore anyways? Cold baths have been found to significantly reduce muscle soreness and tissue swelling resulting from muscle breakdown. The Extra Large and Large Packs have row stitching and can be rolled to serve as a neck, head or leg rest or wrapped around a limb.
Most treatments involved sitting in the water for the entire time, but in some studies, the participants stepped into and out of the water several times. So, is there a place in a well-designed triathlon program for any or all of these facilities? Soreness occurs when waste products like lactic acid settle in your muscles through these dilated vessels. Your body is simply saying your muscles need time to recover," says Cindy. Killer workout that always leaves you feeling great and gets the endorphin's going. And remember the RICE treatment for acute injuries that involve swelling: Rest, Ice, Compression, Elevation.
Having sore muscles after exercising is not uncommon, but that does not mean it's healthy. Muscle aches and pains can stem from a variety of causes. Some people find they can take a lower dose of pain medicine when they also use non-medical treatments. Ice and heat are not substitutes for medical evaluation and treatment. The soreness is the result of torn muscle fibers that become stiff once the body is inactive after a workout. The delayed muscle soreness can make it difficult to work through regular daily tasks sometimes.
Researchers estimate that approximately five million people suffer from the chronic disorder, according to the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS). While these products offer temporary pain relief, athletes should be aware of some warnings and cautions before they reach for that tube of Bengay or the Icy Hot.