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Syndicate Bank PO Admit Card 2016 will be Available at www.syndicatebank.in. Candidates can Check the Hall Ticket/ Call Letter/ Exam Date from the passage given below.
Syndicate Bank PO Admit Card 2016
Syndicate Bank had recently invited applications from the interested and eligible candidates from all over the country for filling up the 400 Probationary Officer vacancies in Various Departments. A huge number of candidates are going to participate in the given examination and eagerly waiting for the detailed information regarding the admit card/ hall ticket. Candidates who are going to attempt the Syndicate Bank PO Examination 2016 and anxiously waiting for the admit card/ exam date can check the details information regarding the syllabus from the passage given below. A written examination for the various Posts is going to be held in upcoming dates. Syndicate Bank is going to hire interested and eligible candidates for filling up these various unfilled posts. So, those candidates who willing to build their courier in Syndicate Bank have already applied for these several vacancies. You just need to click on the direct link which is provided below in order to download your hall ticket.
Syndicate Bank PO Exam 2016 Details
- Examination Conducted by : Syndicate Bank
- Name Of The Examination : Sub Divisional Engineer Posts Examination 2016
- Total No. Of Posts : 400 Probationary Officer vacancies
- Official Website : www.syndicatebank.in
Syndicate Bank PO Hall Ticket 2016
Massive number of candidates have applied for the given examination. Now Those Aspirants who are deliberately waiting for the Admit Card/ Hall Ticket should check the details regarding the Admit Card from the passage given below. After completing of exam, candidates have to get ready for the counselling. Start your preparation as there is less time, download the syllabus and plan the schedule. To download the Syndicate Bank PO Hall Ticket, candidates need to visit the official website at (www.syndicatebank.in) where the Syndicate Bank PO Hall Ticket 2016 download link is available. Click on the desired link to login and enter the details like Application Sequence Number/User id and password. Now you can download the Syndicate Bank PO Exam Admit card. Download it and take a hard copy of it. Follow The given easy steps to download the Admit Card mentioned below.
- First visit official website : www.syndicatebank.in.
- Find and click on Syndicate Bank PO Admit Card 2016 link.
- Now fill your required details and submit it.
- As soon as your Admit card will be displayed in your screen.
- At last take print out your hall ticket for future exam uses.
Click Here To Check Syndicate Bank PO Admit Card 2016 : (Available Soon…….!!!!!!!!)
All Candidates are advised to keep regular check the on the official website of Syndicate Bank at (www.syndicatebank.in) for more information regarding Syndicate Bank PO Admit Card 2016 or stay connected with the same page at (4result.in) for the latest updates. For any type of queries, or feedback regarding the article you can drop your comments in the comment box given below.


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In an ideal world, all jobs with like responsibilities would be compensated equally. But companies don't operate in an ideal world, and competing demands for talent mean some professional positions warrant higher paychecks than others.
As the following case shows, the Equal Pay Act (EPA) doesn't require all positions on the same line of the organizational chart to be paid the same.
Recent case: Deanne Mikols went to work for Reed City Power Line Supply in the HR office as the manager. Her tenure was rocky—upper management considered other management functions more important than HR. Ultimately, the company fired Mikols for alleged poor performance.
Mikols sued, claiming she had been paid less than comparable managers within the company. She claimed that violated the EPA.
But the court tossed out her case. It reasoned that only those jobs that are substantially similar must be paid the same. Mikols tried to compare her job to that of safety and risk assessment managers, but the court said those are fundamentally different positions requiring different educational backgrounds and experience. (Mikols v. Reed City Power Line Supply, No. 1:07-CV-84, WD MI, 2008)
Final note: A good example of equivalent positions are nurse practitioners (NPs) and physicians' assistants (PAs). More women hold NP licenses; more men hold PA licenses. But both professions have similar educational requirements and perform similar, almost identical health care functions, such as administrating medication, performing basic physicals and prescribing some medications. They are functionally equivalent, so the EPA requires equal pay.
Related Articles...
- How to Fire an Employee the Legal Way: 6 Termination Guidelines
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- To pay or not to pay for donning & doffing?
- No evaluations? You could be called 'Out!'
- What are the pros and cons of requiring staff to sign mandatory arbitration clauses?
- Sloppy work heads list of senior execs' pet peeves

subset: commoncrawl


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A warm light brown. Slightly orange-y which looks lovely with blue eyes. Matte. Fairly pigmented and build-able. Blends nicely. Smooth.
A very warm toned medium brown. Reddish undertones. Fairly pigmented and builds nicely. Blends well. Great color to deepen the crease or nice as a all-over lid color. Love this one!
A warm toned medium purple shade. Pigmented and beautifully smooth. Texture is really nice. Ok blending wise. This is a Matte2 shade which has a slightly different formula. From the research I've done I believe this formula is slightly more milled and is suppose to have better color pay off. I don't notice a dramatic difference between the two.
A dark neutral purple shade. A little sheer but easy to build up. Can be a little patchy and difficult to blend.
It can look beautiful in the outer corner or as a liner. Despite its fall backs I use this shade quite a bit. Any suggestions for a better alternative?
Cool toned black. Blue undertones. Pigmented and easy to build up. Since I'm pretty fair I usually only use a small amount. Fairly easy to blend out. Its a nice color if your looking for something a little more subtle than a true matte black. Great for a deep smokey eye or as a liner.
I really enjoy these colors and I use them throughout the week. I'm a big fan of matte shadows though I find some are more hard to work with than others. Pigmentation can be lacking but I find the matte shadows easy to build up which allows you more flexibility. Texture is smooth but not as creamy as other lines. I find Nehru and FIG. 1 to have the most pigmentation. The purple shadows here do tend to fade throughout the day. I like the effect but I do want to put that out there. I probably use Swiss Chocolate the most out of this bunch.


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Items designated as On Display are shown as a sample in our showroom for you to view. Products are not sold off of our showroom floor.
Belfort Furniture offers White Glove in-home delivery and set-up by professionally trained personnel who will unwrap, place, and assemble your furniture in the appropriate room. Delivery is available Tuesday - Saturday. Once your delivery date is scheduled, you will receive a three hour delivery timeframe the day prior to your delivery.
Furniture may be picked up at our warehouse Monday-Saturday from 10AM to 6PM or Sunday from Noon to 5PM. Furniture that is picked-up may require assembly.
For delivery outside of our local metropolitan area, please contact us with your item(s) of interest for a delivery quote! 703-406-7600 or firstname.lastname@example.com
The mix of wood and metal give the coffee table a defined look that will make a statement. The table is eye catching and functional. With the base made of iron, it has an x shape lending more of an industrial feel. The top is a mix of reclaimed pine and poplar wood that is salvaged from old architecture. The top is unique with two trays that can be removed and used elsewhere. When not in use it gives dimension and character to the coffee table.
The Irondale Jax Wood & Metal Coffee Table w/ Trays by Four Hands from Belfort Furniture. We proudly serve the Washington DC, Northern Virginia, Maryland and Fairfax VA area. Product availability may vary. Contact us for the most current availability on this product.
Made from recycled materials like reclaimed doors and salvaged factory machine parts, the Irondale collection presents one-of-a-kind pieces that reflect your individual style. The uniquely blended wood and iron materials give items like the three dining tables wonderful industrial character, mixing urban contemporary designs with traditional components. Chairs feature a combination of buttery smooth leathers and velvets for a truly luxurious feeling and look reminiscent of American libraries from the 1940s. Iron, brass, and linen panels accent select items, elevating each piece with subtle and expertly crafted detailing. Warm and inviting, with a uniqueness that calls to mind the excitement of the perfect "flea market find," the Irondale collection offers environmentally friendly construction and familiar-yet-fresh dramatic style.
The Irondale collection is a great option if you are looking for Transitional furniture in the Washington DC, Northern Virginia, Maryland and Fairfax VA area.
Browse other items in the Irondale collection from Belfort Furniture in the Washington DC, Northern Virginia, Maryland and Fairfax VA area.
This item has been tagged as: Living Room Furniture, Accent Furniture, Occasional Furniture, Cabinet, Cabinet Tables, Storage Tables, Small Storage Cabinet, Chairside Cabinet, Short Cabinet, Accent Cabinet, Commode, Cocktail Tables, Lift – Top Cocktail Table, Storage Table, Cocktail Coffee Table, Cocktail Table with Storage, Coffee Table, Lift – Top Coffee Table, Coffee Table with Storage, Couch Table, Magazine Storage, Sitting Room Tables, End Table, Chairside Table, Coffee and End Tables, Furniture End Tables, Accent Table, Lamp Table, Pedestal Table, Hall Tree, Storage Hall Tree, Hall Tree with Storage, Coat Rack, Hall Tree Coat Rack, Entry Hall Tree, Hat Rack, Hall Trees with Benches, Bench and Hall Tree, Clothes Tree, Hall Tree Furniture, Entry Furniture, Foyer Furniture, Sofa Table, Furniture Sofa Table, Console Table, Sofa Console Tables, Sofa End Table, Secretary Desk, Table Desk, Wine Rack, Wine Glass Rack, Wine Storage, Wine Bottle Storage, Wine Storage Rack, Wine Bottle Rack, Cabinet Wine Rack, Wine Glass Storage, Wine Storage Cabinet, Larder, Kitchen Storage, Dining Room Storage, Occasional Tables
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A sombre Saddam faces his judges
Page Tools
Saddam Hussein ponders a question on the 1982 Dujail massacre.
Photo: AP
The first official image of Saddam Hussein to be seen this year is a videotape showing him being interrogated by judges gathering evidence for his trial.
The undated tape, which was released on Monday, was without sound, but Iraq's Special Tribunal said the former dictator was being questioned about an alleged massacre in the Shiite village of Dujail in 1982.
Almost 1000 people were rounded up and tortured after an assassination attempt on Saddam. At least 15 were reported to have been executed immediately and 400 of those detained are believed to have been murdered. Among those never seen again were at least six babies.
In the new film, two men, one of them Raid Juhi, the chief trial judge, are seen questioning Saddam, 68, who is dressed in a dark suit and open-necked shirt.
He appears relaxed, if sombre, and at times strokes his beard before responding.
Mr Juhi can be seen saying: "Answer the question. Answer the question."
Four of Saddam's former aides were also seen being questioned about their alleged role in the 1988 Anfal campaign, which included a gas attack that killed 5000 Kurds in Halabja. Iraqis may be preoccupied with suicide bombings and kidnappings, but Saddam's rare appearances stir emotions, not least because some of his Sunni Arab supporters are leading an insurgency that has killed thousands.
The release of the tape comes at a time when the Iraqi Government has been pressing the tribunal to speed up its inquiries as it believes the start of the trial will discourage insurgents.
Prosecutors said they had evidence for 500 cases, but the Government said the tribunal would focus on 12 as they are the most thoroughly documented and the likeliest on which to gain a credible conviction.
Most Iraqis view a guilty verdict - followed by the death sentence - as inevitable given the scale of Saddam's crimes and the hatred with which he is held by those now ruling Iraq.
But the authorities know the trial will be the focus of international attention and are determined a conviction is seen as legally fair.
- Telegraph
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dogfishnoun [ C ]uk /ˈdɒɡ.fɪʃ/ us /ˈdɑːɡ.fɪʃ/ plural dogfish or dogfishes
Examples from literature
- He compared these gill-slits with those of a dogfish.
- It is fished by small boats and vessels when the dogfish are on the outer grounds.
- Seal and dogfish follow the salmon.
- Some big dogfish also passed by, a voracious species of shark if there ever was one.
- You'll scare even the sharks and dogfish away.


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Coronary Flow Reserve from Mouse to Man—from Mechanistic Understanding to Future Interventions
- First Online:
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Myocardial ischemia is recognized as an important mechanism increasing the risk for cardiovascular events in both symptomatic and asymptomatic patients. In addition to obstructive coronary diseases, systemic inflammation, macro- and microvascular function are additional important mechanisms contributing to the ischemic myocardium. Accumulating evidence indicates that coronary flow reserve (CFR) is a quantitative measurement of ischemia including integrated information on structure and function of the coronary artery at all levels. Not surprisingly, CFR has been shown to confer strong prognostic value for hard cardiovascular (CV) events in a number of relevant patient cohorts. Using high-resolution imaging, it is now possible to study coronary arteries from mouse to man. Therefore, CFR may be an important translational tool to risk-stratify patients and to perform both preclinical and clinical proof-of-concept studies before investing in large-scale outcome trials, thus improving the translational value for novel CV targets.
KeywordsCoronary flow reserve Ischemia Cardiovascular events Risk-stratification Cardiac catheterization PET CT MRI Transthoracic echocardiography Color Doppler Translational medicine Microvascular function Systemic inflammation Ischemic myocardium
During the last decade, a decline in age-adjusted cardiovascular (CV) mortality has been observed [1]. Increasing public awareness as well as recent advancement in medical and surgical interventions are considered contributing factors to this positive trend. However, ischemic cardiovascular disease remains the number one killer in the westernized world and increasing prevalence of diabetes and obesity is believed to accelerate the global cardiovascular disease burden [2].
There is accumulating evidence indicating that myocardial ischemia is an important cause associated with residual CV risks among both symptomatic and asymptomatic CAD [3, 4]. Indeed, transient ischemia could also lead to sudden death due to lethal arrhythmia [5, 6, 7]. In the setting of chronic stable ischemic heart disease, angiogram-guided percutaneous coronary intervention (PCI) has not been shown to deliver superior benefits compared to optimal medical treatment, while a fractional flow reserve (FFR)-guided approach, which measures the hemodynamic significance of stenosis, has begun to demonstrate promising results (FAME II) [8].
Acute myocardial infarction (MI) is considered an atherothrombotic event, which in turn is under the influence of three major triggers according to Virchow's triad: vessel injury either through plaque rupture or endothelial erosion, hypercoagulability and finally reduced and/or disturbed flow [9, 10]. In the arterial system with normal blood flow velocity around 1 m/s, flow-stopping atherothrombosis is rare, while in the venous system with slow and occasionally stagnated flow, thrombosis may occur without atherosclerosis. In contrast to most other arteries, where flow occurs predominantly in systole, coronary perfusion is mainly a diastolic event. Also, the normal blood flow velocity in the epicardial coronary arteries is much lower than in for example: aorta and carotid arteries [11]. The unique anatomy and physiology of the coronary circulation require specialized physiological adaptations. Understanding the biology of the coronary vascular bed may help us to risk stratify patients as well as identify novel treatment regimes to combat coronary artery disease.
Concept of Coronary Flow Reserve
The concept of coronary flow reserve (CFR) was introduced to reflect the maximal oxygen delivery capacity during increasing demand. Since cardiomyocytes are capable of extracting oxygen with great efficiency already at rest, the only way of meeting increasing demand is to increase coronary blood flow [11, 12]. At rest, there is a significant autoregulation in the coronary vascular bed which ensures sufficient blood supply to the cardiomyocytes under a wide range of perfusion pressure. Thus, resting coronary blood flow is mainly under control of tissue metabolic demand [13]. To test the maximum flow reserve capacity, the autoregulation must be uncoupled, which will create a linear relationship between perfusion pressure and flow. Thus, CFR is usually measured during either exercise challenge or pharmacological stimuli such as dobutamine and adenosine [14].
Hemodynamically significant coronary lesions are known to cause reduced CFR [12, 14]. In the case of diffuse coronary artery atherosclerosis without angiogram-visible significant stenosis, CFR could be an objective tool to assess the hemodynamic significance, not necessarily reflected by distinct local stenosis. This has been comprehensively described by Dr. Gould et al., who pioneered the concept in humans [15]. However, impaired CFR could be due to many other pathological conditions, such as microvascular dysfunction in for example: diabetic patients [16]. Interestingly, the presence of thin cap fibroma in the coronary artery has been reported to be associated with impaired CFR, indicating an important but not completely surprising link between atherosclerotic lesion composition and downstream vascular function [17].
While FFR seems to be a fit-for-purpose tool to address hemodynamic consequences of focal lesions, CFR could be a measure of the entire coronary vascular functionality. Even though there is correlation between CFR and FFR, significant discrepancy between these two measures is evident, which may suggest that they indeed reflect distinct aspects of the coronary arteries [18]. This means that not all patients with impaired CFR would have any intervenable coronary lesions according to FFR, and that CFR will not necessarily be improved even following the best FFR-guided PCI procedure.
Methods to Assess CFR in Man
Coronary flow reserve can be measured using many modalities. Thermodilution was one of the invasive techniques used to determine CFR in man [20]. Coronary flow velocity reserve (CFVR) can be measured using invasive Doppler-guide wires using, for example adenosine as a stress agent [21]. Recently, a combined FFR and CFVR catheter has been launched for simultaneous flow and pressure measurement [22].
Non-invasive techniques have been developed during the last two decades taking advantage of modern high-end imaging modalities. Positron emission tomography (PET) is now established as the gold standard for absolute coronary blood flow and flow reserve measurement. PET provides both ischemia evaluation as well as absolute flow quantification [23]. Various tracers can be used including those that do not require a full-scale cyclotron facility, for example: rubidium [24]. In combination with high-resolution computer tomography (CT), this modality can provide both structural and functional information about ischemic heart disease [25]. Even though PET is an established approach to assess CFR, radiation exposure as well as high equipment and running cost limit its wide use. Contrast CT might be a new modality for perfusion imaging. This method is also associated with radiation although the level of radiation has decreased substantially with the latest generation CT [26]. Magnetic resonance imaging is a non-radioactive valuable method, capable of assessing CFR, but is relatively costly and time-consuming [27].
Myocardial contrast echocardiography is an inexpensive and non-radioactive method for measurement of CFR. When image quality is adequate, CFVR as well as CFR can be readily measured [28]. However, for accurate and reproducible quantification of CFVR and CFR, high-quality images are required both during rest and hyperemia allowing contrast intensity measurement to derive flow velocity as well as steady-state flow signals.
Transthoracic color Doppler echocardiography (TDE-CFR) has been successfully used to measure coronary blood flow velocity (CBFV) and CFVR [29]. With proper machine setting and skilled hands, the technique is non-radioactive and feasible in every echo-lab without need of contrast agent. Using this approach, success rate is greatest in the left anterior descending (LAD) coronary artery. In addition, right posterior descending coronary artery [30] as well as circumflex artery (LCX) CFBV is measurable [31]. Accuracy of these approaches has been validated previously against invasive techniques [30]. Technically, for access to the distal LAD, only a small echo-window is needed compared to for example: left ventricle ejection fraction measurement using Simpson's rule, where a couple of cm echo-window is needed for good image quality. Thus, obesity is not an absolute hurdle for the success of this technique [32]. For real-life clinic use of this technique for diagnosis of ischemic heart disease including obstructive CAD and microvascular disease, dipyridamole-assisted TDE-CFR has been successfully applied on a routine basis in combination with wall motion analysis [33]. Using this approach, the high specificity of stress echo can be combined with the high sensitivity of CFR for diagnosis of ischemic heart disease in patients with suspect CAD.
Determinants of CFR in Man
To further understand biological processes and the clinical relevance of CFR, numerous studies have been performed to relate CFR to cardiovascular biomarkers. These studies revealed that CFR indeed could serve as a composite physiological marker of systemic CV risk. Besides obstructive CAD, which is an obvious determinator of CFR [12, 14], impaired CFR has been reported in patients with dilated cardiomyopathy [35], as well as patients with diabetic vascular complications [36]. Further, myocardial capillary density has also been shown to determine CFR in patients with dilated cardiomyopathy [37].
CFR is rheologically associated with blood viscosity, which in turn is dependent on lipoprotein and fibrinogen levels. In familiar hypercholestoremic patients, CFR is related to LDL level and is improved after LDL apheresis, supporting the concept that increased blood viscosity due to extremely high LDL level can be a determinant of CFR [38].
CFR has also been shown to correlate to markers of low degree systemic inflammation, such as C-reactive protein [39] and neutrophil count [40]. Based on large-scale genetic association studies, IL-6 has recently been shown to be causally linked to CV outcome alongside LDL-regulating pathways [41]. Interestingly, a PET-CFR study conducted in twins showed that IL-6 indeed was a determinant of CFR in those asymptomatic subjects [42].
It is well-known that endothelium plays a central role in CV disease etiology and progression [43]. Even though CFR is measured using a non-endothelium dependent vasodilator, for example: adenosine, for achieving maximum hyperemic flow response, intact endothelial function is required. CFR has been shown to be associated with peripheral endothelial function both in chest pain patients and in healthy volunteers [44, 45] and direct inhibition of the nitric oxide pathway reduced hyperemic response in healthy volunteers [46].
Prognostic Vaules of CFR in Man
Impaired CFR has been shown to confer great prognostic information for hard CV outcome, including all cause mortality, CV death and non-fatal MI. Independent of imaging modality used, the prognostic power of CFR appears to be consistent. In post-MI setting, invasively assessed CFVR showed prognostic value in the "DEBATE" study. In such a setting, microvascular obstruction as well as infarct size may impact on CFVR alongside residual ischemia [47]. This concept has been extensively evaluated in patients with suspected coronary artery disease since they are undergoing ischemia testing based on clinical indication. In these patients, CFVR adds incremental prognostic values on top of wall motion analysis in terms of prediction of mortality and spontaneous CV events [33]. Interestingly, in the paper by Murthy et al., PET-CFR magnitude dependently predicted CV mortality across various levels of infarct size, ischemic burden and LV ejection fraction [48]. These data strongly supports the concept that CFR rather than just obstructive coronary artery disease contributes to CV vulnerability. In line with this, Murthy et al. showed that diabetic subjects without previous CAD but with impaired CFR had the same risk as non-diabetic patients with CAD [49]. Further, CFR showed great prognostic information in patients with dilated cardiomyopathy [50], which suggests that impaired CFR is an independent risk driving CV events in additional patient cohorts. In the context of post-infarct cardiac remodeling, impaired CFR is an independent predictor of adverse left ventricle remodeling [51]. The quantitative nature of CFR measurement is also reflected in its prognostic information, since it has also been shown that CV outcome is related to CFR in a magnitude dependent manner, that is the lower the CFR the worse the outcome and vice versa [48].
Transplant vasculopathy is a phenomenon of diffuse coronary artery disease for which traditional angiogram-based approaches cannot be used to follow the disease progression. In these patients, CFVR has been successfully used as a prognostic marker [52]. This further supports the concept that the integrative physiological assessment of the coronary functionality is of greater importance than only the luminology-based approaches.
Effects of Established Interventions on CFR in Man
CFR and pharmacological interventions
Mode of action
CFR before treatment
CFR after treatment
Treatment duration
No angiography-verified CAD and normal cholesterol
Atorvastatin vs placebo
2.47 ± 0.34
3.02 ± 0.54, p = 0.0012 (no change in placebo)
1 h
Fluvastatin (no placebo)
3.0 ± 0.5
3.5 ± 0.8, p < 0.01
3 months
Atorvastatin: low-dose (LD) 10 mg or moderate-dose (MD) 40 mg
LD: 2.58 ± 0.67, p < 0.05 MD:2.96 ± 0.73, p < 0.05
8 months
Slow coronary flow
Atorvastatin (no placebo)
1.95 ± 0.38
2.54 ± 0.56, p < 0.001
8 weeks
Telmisartan vs nifedipine
2.4 ± 0.4
2.9 ± 0.4 p < 0.01 (no change in Nifedipine)
12 weeks
Hypertension and microvascular angina pectoris
Enalapril (in hypertensives vs normotensive patients with hypertrophic cardiomyopathy)
2.2 ± 0.6
3.3 ± 1.2 (p < 0.001) (no change in normotensive patients)
11 to 13 months
Perindopril (no placebo)
2.1 ± 0.6
12 months
Hypertension and LVH
Lisinopril vs losartan
2.4 ± 1
3.7 ± 1.1, p = 0.002 (no change in Losartan)
12 months
Diabetes + albuminuria
Eplerenone vs hydrochlorothiazide
1.38 (1.11–1.61)
1.57 (1.36–2.14) vs hydrochlorothiazide 1.30 (1.08–1.47) , p = 0.03
6 weeks
Diabetes + LVH
Perindoprilat vs placebo = saline
2.7 ± 1.0 Saline infusion
3.9 ± 0.9, p < 0.001 perindoprilat infusion
Acute infusion
Fenofibrate vs placebo
2.8 ± 0.58
3.14 ± 0.36,P < 0.01 (no change in placebo )
6 months
Rheumatoid arthritis
Single dose Anankinra vs placebo (4 h) and Prednisolon (1 month)
2.39 ± 0.6
4 h: 2.85 ± 0.7, p < 0.001 1 month: 3.08 ±0.5, p < 0.001 (no change in placebo or Prednisolon)
4 h and 1 month
IDC and hyperuricemia
Allopurinol (no placebo)
1.87 [1.63–2.00]
2.20 [1.87–2.49], p < 0.001
3 months
LDL Apheresis
Blood viscosity lowering approaches, for example: LDL apheresis, induce acute improvement of CFR in familiar hypercholesterolemic patients with extraordinarily high cholesterol levels [38].
Statins have shown both acute effects on CFR probably through pleiotrophic effects but also in the medium-long term, which most likely is due to their LDL-lowering anti-atherosclerotic effects.
Anti-hypertensive drugs such as angiotensin-converting enzyme blocker or receptor blockers have shown beneficial effects on CFR through their effects on endothelium as well as anti-inflammatory properties. Decreased afterload following successful blood pressure normalization will also contribute to improvement of CFR due to reduced oxygen demand.
In patients with increased systemic inflammation such as reumatoid artheritis, blockade of IL-1 pathway using anankinra immediately improved CFR and increased peripheral endothelial function as measured by flow-mediated forearm vasodilation as well as pulse wave velocity. Compared to prednisolon, which did not show any impact on the cardiovascular system in these patients, this treatment demonstrated sustained effects on these endpoints also at one month follow-up. The beneficial CV effects were also associated with a decrease in systemic inflammatory markers.
Translational Aspects from a Drug Discovery Perspective
Discovery and development of novel anti-atherosclerotic drugs to reduce cardiovascular events on top of standard of care is an area of high risk. Several difficulties have to be overcome in order to succeed with delivering a positive outcome in phase III trials. Traditionally, novel targets and compounds are validated in pre-clinical models of atherosclerosis with the primary read-out being a reduction in plaque progression/size. Often such data provide the sole basis in terms of in vivo intervention data before investing in large clinical programs. For clinical proof-of-concept, primary end-points have focused on plaque centric endpoints such as plaque volume, intima-media-thickness or plaque composition. Although these endpoints are associated with CV disease and CV events, limited information is available on how intervening with these endpoints affects CV benefit. This is not surprising since, atherosclerotic plaques are only one component contributing to the ischemic myocardial event in humans. Many additional biological mechanisms have been shown to play a role in triggering the event including microvascular dysfunction, endothelial dysfunction, systemic inflammation, vasospasm, thrombosis and angiogenesis [67, 68, 69, 70]. By using a more integrative approach for proof-of-concept both pre-clinically and clinically, clinical development could be potentially de-risked.
To study the effects of novel anti-atherosclerotic compounds in animals within reasonable time frames, disease progression needs to be accelerated by genetic manipulation and/or feeding high-fat high-cholesterol containing diet. No single animal model available today mimics all aspects of this complex human disease and it is important to note in particular that no model reliably and reproducibly replicates the rupture and subsequent thrombotic occlusion of coronary arteries. As discussed previously, the pathophysiological events that occur at the level of the atherosclerotic plaques have been of great interest during the past few decades and also in animal studies targets which are involved in reducing plaque progression have been in focus for potential future interventions for reducing cardiovascular events. To gain confidence in potential novel therapies for reducing CV events, it is crucial that pre-clinical studies focus on the proper vascular bed and the relevant translational endpoints. Despite the prevalent use of mouse models of atherosclerosis, few have focused on the coronary arteries due to technical difficulties with studying these small arteries. Fortunately, due to recent advances with high-resolution imaging, it is now possible to perform morphological and functional imaging studies of cardiovascular systems in living mice [71, 72, 73, 74]. This has dramatically increased the translational value of preclinical disease models and may provide guidance for dose selection and Proof of Principle studies in humans.
Effects of Interventions on CFR in Rodents
Statins have become a standard therapy for CV patients and any novel therapy will need to demonstrate significant benefit on top of statins. Thus, back translation of statin effects to animal models is of fundamental importance for drug discovery and development. In addition to their cholesterol lowering effects, statins have been shown to retard the progression of atherosclerosis [81], improve endothelial function [82], reduce systemic inflammatory markers and reduce cardiovascular mortality [82, 83, 84]. The response to statins in animal models varies with species, strain, gender, diet and protocol used. Although statins reduce plasma cholesterol and plaque area in some murine models, the exact mechanisms behind the cholesterol lowering effects are largely unknown. Statins have shown to reduce atherosclerosis in the apoE*3Leiden by changing lipoprotein profiles and total lipid levels [85, 86] in plasma. However, the so called "pleiotropic effects" may also play a significant role in this model [87]. In apoE- and LDLr-deficient mouse strains, statins have shown variable results on plasma cholesterol levels and plaque progression. ApoE-deficient mice on a mixed C57BLl/6 and 129SvJ (Taconic Denmark) background on a high-fat diet (21 % pork lard and 0.15 % cholesterol) responded to rosuvastatin in a human like manner. Plasma Cholesterol levels were reduced on average by 20 % during the 16-week study period [88]. In addition, brachiocephalic plaque area and the inflammatory serum biomarker serum amyloid-A (SAA) were significantly reduced at the end of the study suggesting additional effects similar to those observed in humans. Assessing coronary artery flow, calculated from UBM measured coronary diameter and color Doppler echocardiography flow velocity revealed an increase in hyperemic blood flow at the end of the study, again in line with findings in humans. Generating data in this animal model responding to statin therapy in a human-like way will improve our confidence in novel targets and facilitate future translational drug intervention studies in mice.
Grönros et al. used the TDE-CFVR approach to document effects of a novel arginase inhibitor, which may act by restoring normal nitric oxide balance in the vascular endothelium. In a rat model of type 2 diabetes, microvascular dysfunction as measured by CFVR was demonstrated relative to control rats. Further, the arginase inhibitor succeeded to improve CFVR only in diabetic rats and not in control rats [89].
CFR as a Translational Tool for Target Validation
We and others have shown that CFR in vivo is reduced in late stage mouse atherosclerosis mouse models [72, 90], but also in the absence of coronary arthrosclerosis such as in models of diabetes [91], blood pressure overload induced heart failure [92] and myocarditis [73]. CFR can thus be measured in various disease models in vivo for exploration of disease mechanisms and might be used to validate novel drug targets.
5-Lipoxygenase (5-LO), five lipoxygenase activating protein (FLAP) and its products leukotrienes B4 (LTB4) and cysteinyl leukotrienes (cys LTs) have been linked to cardiovascular disease [93]. The ALOX5AP (FLAP) haplotype HapA has been associated with risk of MI [94] and levels of 5-LO, FLAP and LTA4H mRNA in human carotid plaques have been correlated with the occurrence of plaque instability [95]. In a phase II study, the 5-LO inhibitor, VIA-2291 reduced coronary plaque volume and new formation of rapidly growing coronary lesions in ACS patients following 6-months treatment [96]. These findings are in great agreement with many preclinical studies performed in animal models of atherosclerosis [97, 98].
To further explore the potential role of the 5-LO pathway in low degree subclinical inflammation and coronary vascular function, we carefully investigated CV function in 5-LOX-deficient mice (AstraZeneca Transgenic Centre, Mölndal, Sweden). We hypothesized that these mice could be protected from deleterious effects of lipopolysaccharide (LPS) challenge in a low-grade inflammatory, sub-acute setting.
Higher doses of LPS might induce septic shock with acute effects such as myocardial contractile dysfunction, drop in systemic blood pressure, vasoplegia, tissue hypoperfusion, microvessel injury and multiple organ injury [99], whilst low or moderate doses of LPS have been shown to induce endothelial dysfunction in experimental settings [100]. Our data seems to be consistent with the previous findings that 5-LOX-deficient mice maintain blood pressure control better than control mice [101] and rats treated with a 5-LO inhibitor (Zileuton) showed reduced organ failure [99] following severe LPS endotoxemia. In addition to mediating inflammation [93, 102], direct vasoactive actions of the LTs have been frequently reported in both coronary [103] and aortic [101] arteries of several species. Thus, 5-LO metabolites seem to have both direct and indirect vasomodulating properties, especially in abnormal conditions, as observed in atherosclerotic arteries of humans [103]. Taken together, in addition to its anti-atherosclerotic effects, 5-LO pathway inhibition may also improve coronary vascular function in patients with systemic low-grade inflammation.
Concluding Remarks
In summary, accumulating evidence indicates that CFR may serve as a composite marker for coronary macro- and microvascular status, as well as systemic risk profile. Quantitative measurement of CFR provides us with an accurate prognostic tool to risk stratify patients as well as to follow disease progression and potential effects of intervention. Mechanistically, CFR is closely associated with many major pathoetiological factors driving residual risk in CV patients, such as epicardial vessel atherosclerosis burden and composition, left ventricle hypertrophy, vascular rarefaction, dyslipidemia, subclinical inflammation, endothelial dysfunction, etc. Establishment of the translational imaging techniques opens up exciting possibilities for deepened mechanistic understanding of this important pathophysiological phenomenon. Accumulated knowledge will hopefully accelerate development of novel therapeutic approaches targeting unexplored pathways to improve CFR and thereby further reduce CV mortality and morbidity. A translational approach and comprehensive understanding of the biology may potentially de-risk clinical development programs of novel therapies. In addition to treatment correcting dyslipidemia and emerging drugs to reduce systemic inflammation, recent scientific progress within regenerative medicine may also in the not too distant future contribute to step-change therapies in terms of for example: regeneration of cardiomyocytes and coronary microvessels, and thereby restore a functional myocardium with well-dimensioned vascular bed.
We are grateful to Dr. Carl Whatling and Mrs. Karin Mörup for excellent editorial assistance.
Conflict of Interest
All authors are employers of AstraZeneca R&D but have no conflicts to disclose in relation to this paper.
Copyright information
Open Access This article is distributed under the terms of the Creative Commons Attribution License which permits any use, distribution, and reproduction in any medium, provided the original author(s) and the source are credited.


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|Supplement Facts
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Other Ingredients: Gelatin (Capsule), Magnesium Stearate, and Silica.
Directions: As a dietary supplement, take one capsule twice daily with food.
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Fall 2016 Region 5 Board Meeting and Chapter Leaders Workshop to be held October 12-14, 2016 in Appleton, Wisconsin
The 2016 AITP Region 5 Fall Board Meeting and Leadership Workshop will be held in Appleton October 12-14, 2016. Region 5 will join the Northeast Wisconsin (N.E.W) Chapter as it hosts its monthly chapter meeting Wednesday evening (Oct 12), a Technology Hub Conference all day Thursday (Oct 13), and then the Region 5 Board Meeting and Leadership Workshop Friday morning (Oct 14). There is no charge to attend the Region 5 meeting or the Leadership Workshop, but, there will be small costs to attend either the Northeast Wisconsin Chapter Dinner meeting or the Technology Hub Conference.
The base hotel for all of the events is:
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See this video about the conference:
The Region 5 Fall Board Meeting will take place at the hotel at 8:30 am Friday (October 14th) at the Radisson. An agenda for the meeting will be forthcoming shortly. As always, the meeting will be followed by a Leadership Workshop, the topic of which we are finalizing now.
Click here for the Fall Region Meeting Agenda.
This is shaping up to be quite the event! Plan now to attend and SAVE THE DATES!
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Farragut (Knoxville, Tenn.) High School tight end Jacob Warren checked out another ACC school Tuesday and got a chance to visit with an old friend — Wake Forest offensive lineman Nathan Gilliam.
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Warren got to see the school and some of the new facilities — the new indoor practice facility and a video showing the upcoming additions.
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As the offers pile up and the visits mount, Warren and his family are spiraling toward an endgame.
"Me and my family have talked about it, and if I know where I want to go by the beginning of the season then that's probably when I will make a decision," Warren said. "I think by that time I should be pretty solid. We're thinking mid-season at the latest."


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Originating from Austin, Texas, USA, the Gourds distinctive alternative country sound marries influences as diverse as Lynyrd Skynyrd, David Bowie and Charlie Daniels. The band was formed in the mid-90s by singer/guitarist Kevin Russell (Beaumont, Texas, USA), a veteran of outfits including the Picket Line Coyotes, whom he once described as a cross between Hüsker Dü and Hank Williams. They released three albums, Fashion Dogs, Upholstery Van Songs and We Shall Annex The Sudetenland, in the late 80s and early 90s, the latter pair being self-released cassettes. Among Russells colleagues in Picket Line Coyotes was Robert Bernard, whose younger brother Claude later became a founder member of the Gourds. The Picket Line Coyotes broke up in 1991, shortly after another future Gourds member, Jimmy Smith, had joined them.
For two years following the break-up Russell played open mic sessions, preparing two unreleased solo albums....
- MatchThe Gourds
- 100%Blue Mountain
- 85%Old & In The Way
- 83%Patterson Hood
- 66%Todd Snider
- 65%Tift Merritt
- 61%Fred Eaglesmith
- 61%Joe Ely
- 61%Uncle Tupelo
- 60%Hayes Carll
- 57%Old 97's


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For sale by Empic star int'l ltd- VERIFIED SELLER VERIFIED19 Feb 7:20 pmIkeja, Lagos
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|1,627 sq. ft.
|Property type
|Minimum Stay
|29 nights
Our beautiful two bedroom plus den condo features sweeping west-facing, night-lit views of the Santa Rosa mountains. Located on the 8th fairway of the Arnold Palmer private course and adjacent to one of the crystal-clear community pools and spas, this desert oasis is quiet and comfortable.
The kitchen has been recently renovated and features granite counter-tops and top-of-the line stainless steel appliances. There is a bar-counter for added seating and convenience. We have fully stocked the kitchen with appliances and linens for everyday and for entertaining. In the mornings, you can enjoy fresh grapefruit picked from a tree on our property.
The high-ceilings and open concept of the living room make it an airy, comfortable place to relax while taking in the views through the windows. A wet bar and fireplace add to the vacation ambiance.
Both bathrooms have glassed-in showers with tile floors and quality fixtures. Flat screen TV's in the living room and master bedroom, tasteful decorating throughout and a new washer/dryer set will make your stay comfortable and enjoyable.
The outdoor patio areas feature a cosy, new sectional for lounging, as well as a table and gas BBQ for outdoor dining. You will enjoy watching the sun set behind the Santa Rosa mountains which are then lit-up for a magical effect.
Our extended family is located in the Vancouver-area of British Columbia and we look forward to our warm-weather holidays for the relaxation and recreational opportunities they provide.
Carolyn Warner purchased this condo in 2013
We chose our PGA West condo on the Arnold Palmer private course after a two year search for a west-facing, one-level condo with a golf course/mountain view - having the pool and hot tub located next door is a bonus!
We love the beauty and quiet of the PGA West development and its proximity to Old Town La Quinta and all that the Palm Springs-area has to offer.
Stayed for 10 days last December. The condo was wonderful as was the owner Carolyn. Everything worked out very well and we loved the location and the condo itself. The area was great for walking and I even saw some wild sheep!! They were next to the mountain range and I saw them on a walk. Would love to return.
I would like to begin by thanking Carolyn, the owner, again for a great stay in her very comfortable, updated and clean condo! The condo lacked for nothing, right down to a sewing kit ~ just in case! We had a great month at PGA West. Loved the location of this condo and the fabulous views of the Santa Rosa Mountains and 8th Fairway. Also nice, the pool and hot tub are conveniently located right next to the condo as well. Carolyn is a very responsive owner to any needs you may have. It was indeed a pleasure vacationing here.
Fantastic satiate PGA west. this condo was very clean and comfortable.
The pool is right out the door and very luxurious.
Cant wait to come again
This condo exceeded our expectations; totally up-dated, tastefully decorated, very well-equipped and super clean. Having the pool and hot-tub right next door was an added bonus. We enjoyed it every day during our stay and seemed to be the only ones using it.
My favourite place was the great outdoor couch where we enjoyed the beautiful mountain view, especially at sundown. We would definitely recommend it to family and friends.
This condo had it all. As soon as you walked in you knew the photos hadn't exaggerated or misled. It was spotless, spacious, modern, well-equipped and tastefully decorated. Our dealings with the owner were enjoyable and efficient. Watching the sunset over the mountain from the wonderful patio couldn't have been better. The pool and hot tub were right next door (but never noisy). All the kitchen essentials were there and it was a pleasure cooking in this modern space with all new appliances. The whole PGA West area is very quiet and peaceful, with beautiful landscaping, abundance of pools and hot tubs and top-notch security features. It is close to grocery shopping and some of the best happy hours in the valley. We would definitely try to rebook this condo for another visit.
We spent 3 weeks and enjoyed every minute. The unit is very comfortable, fully equipped and has one of the best views of the mountains. The bath tubs have been replaced with new tiled showers, which we love. One of the best features is the modular outdoor couch for watching the sun set behind the mountains and to watch the golfers go by. The unit is next to the pool and hot tub. The area is beautiful for morning walks. We were so please with the owner's help and concern for enjoying our visit. There are bigger units, but this one had everything that we needed. Hope to return.
The laid-back atmosphere and walking/biking/hiking trails of La Quinta make it the ideal spot for couples and families looking for relaxation and recreation. Our beautiful condo is located just inside the main entrance of the world-class PGA West development and a five minute drive from Old Town La Quinta and Silver Rock Golf Course.
Trader Joe's, Costco, Starbucks and much more shopping and dining are just a ten-minute drive away. The Indian Wells Tennis Centre and La Quinta Resort and Spa are also within minutes of the condo.
|Rate Period
|Weekend Night
|Monthly *
My Standard Rate
29 night minimum stay
|Refundable damage deposit
Effective May, 1, 2017 there will be a cleaning charge of $150 added to your monthly rental rate.
30 day minimum rental. A booking deposit of $400 per month of stay is required within one week of booking.
December thru April - $4500/month
May-November - $3000/per month
* Approximate monthly rate. Actual rate will depend on the days of the month you stay.


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The newest and the most vibrant resort in Harbour Front destination on Harbour Island is Valentines Resort. Even though the architecture of Valentine's luxury accommodations was inspired by the historic dwellings that once dotted Harbour Island, they have modern facilities.The property offers a perfect collection of unmatched suites on the island. Shady verandas, hibiscus and bougainvilleas, and the allure of turquoise water and pink sand beach make this an idyllic Caribbean island.
Accommodations spacious interior feature a stylish decor, marble bathroom and a masterpiece kitchen.These beautifully appointed vacation homes come fully furnished with real Brazilian hardwood floors, leather furniture, and granite counter-tops.
The timeless architecture, a popular state-of-the-art marina plus PADI dive center and international dining flaunt this property's facilities. The resort is set close-by the best shopping and within an easy stroll to Pink Sands Beach.
Valentine's special spa packages let you experience the transformative effect of a combination of treatments. The world-class service includes a variety of massages, scrubs, aromatherapy, body wraps, skin care, facials, manicures and pedicures, salon services, and make-up.
Escape into an idyllic world of island comfort, relaxation, and rejuvenation. Indulge yourself with the luxurious island experience you deserve. In this little Harbour Island oasis you can let your stress fade away, your muscles and skin rejuvenate, and your energy renew. The friendly and professional staff will pamper you, helping to heal your body, mind, and soul.
We are happy to give you a call back to discuss your holiday at a convenient time for you or we welcome you to come to our office in central London to discuss your holiday in detail.
Our destination experts provide a personalised service to tailormake your dream holiday. Within our experienced team we have visited most of the properties we feature and will be able to give you expertise and specialist knowledge from our first hand experience. You will be offered a direct telephone number, so you are able to speak to the same specialist from the time you pick up the phone until your documents are sent out.
No, we tailormake all our holidays and subject to availability you will be able to travel on any date. The itineraries and holidays on our website are for inspiration and are suggestions only, you can change any aspect according to your personal requirements and available spend.
Many customers are under the illusion that booking late secures the best prices. This is often not the case and it is advisable to book early especially if travelling in peak seasons such as Christmas, Easter or school holidays. Many hotels and airlines actually offer special "Early Booking Offers" so you are able to secure the best price early on.
It's always a difficult decision to make before you travel. Call one of our destination experts, who will be happy to advise you on local restaurants and prices you can expect to pay in resort.
There are many excursions, activities and highlights that are not to be missed out on, whilst in the country. Please contact our experts for advise on whether to prebook these before travel.
When booking through Western and Oriental, if your flight is delayed or cancelled due to bad weather or you have a problem in resort it is our responsibility you are taken care of. We offer a 24 hour emergency number to assist with any issues you may have in resort and all of our flight inclusive holidays are financially protected through ATOL bonding for your protection.
The Bar - The dockside bar offers entertaining ambience welcoming locals and visitors alike, offering light bar snacks alongside a good selection of alcoholic and non- alcoholic drinks.Open until late.
Cocoa Coffee House - Perched on the 2nd floor of a recently restored historical building you can enjoy Starbucks and Lavazza brand Coffees. Open Monday through Saturday 7.00 to 17.30 and Sundays 7.00 to 13.00
Restaurant opening times are to be used as a guide only and can vary throughout the year depending on resort occupancy levels


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Free Download APK Android Psy Penguin Vs Infinity AdFree | Only best games at Sbenny.com
Game Description:
This is the AD FREE version of Psy Penguin Vs Infinity, the infinite bullet dodging shoot-em-up game inspired by Japanese bullet hell classics! Collect bonuses, power-ups and phasers to clear the screen.. whatever you do just don't get hit by anything red - and don't forget to dodge the asteroids too!
Game Requirements and Details:
Android version required: 2.3 and higher versions of Android Smartphones and Tablets
Required storage space: 39 MB or more
Internet connection NOT required to play
APK ID: com.psypenguin.adfree
Last game version: 1.0.8
Genre: Action
Price: €1,27 with NO In-App Purchases
Ads? NO
Installation Instructions:
- Download one of the [APK] files below (the MOD version is the HACKED game) OR try the [Google Play] version;
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Broken Link? Outdated Version? Report it! Want us to make a custom MOD for you? Visit our dedicated Forum!
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October 19 2016
(SPOILER) Agents of SHIELD 4x05 Promo "Lockup." An ancient book in the hands of a mad scientist ghost...
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A MAN who was one of three trustees who helped set up the Bradford City fire charitable trust has died peacefully after a short illness at the age of 91.
Gerald Hodges came to Ilkley from Sussex in 1970 to be treasurer for the former Ilkley Urban District Council.
When boundary changes came into force in 1974 he became director of finance at Bradford Council where he remained until he retired in June 1985.
He also became honorary treasurer of the University of Bradford.
During World War Two Mr Hodges served as a telegraphist in the Royal Navy between 1943 and 1946.
He became a veteran of the Arctic convoys, sailing on HMS Tracker escorting convoys to Russia. At the end of the war he served on HMS Zest, part of the Royal Navy squadron stationed in Kiel.
Three years ago his son, Michael, an organist in London, collected the Ushakov Medal, presented to Arctic convoy veterans, from the Embassy of the Russian Federation, in London, and presented it to his father.
A keen ornithologist and gardener, Mr Hodges continued to live in Victoria Avenue, in Ilkley, where he maintained a pristine garden. He was also a regular member of the congregation at St Margaret's Church, in Ilkley.
"My father was really very sharp in mind and looked after himself almost right up to the end. He spent only a week in care in Burley Hall before he died," said Michael.
"Prior to going into Burley Hall, my father had spent a short time in Sue Ryder, Manorlands, in respite, but did return home and received fantastic support from the nurses," he added.
Another son, Colin, died in 1975 from leukaemia at the age of 18. Mr Hodges' wife, Betty, died in 2004.
Mr Hodges was instrumental in setting up the trust fund that supported people involved in the Bradford City stadium fire on May 11, 1985.
Mr Hodges, along with the Council's then chief executive Gordon Moore and Bradford lawyer Roger Suddards, set up a discretionary charitable trust for the Disaster Appeal within days and at the close of the fund the following year, had been able to pay out more than £4.25 million to 400 people.
The cost of administering the fund was kept at one per cent of the total. The three trustees were not paid.
Michael added: "He was very proud of the work the trustees did in setting up the fund and which itself became a template for subsequent disasters that occurred - capsizing of the Herald of Free Enterprise ferry at Zeebrugge, the Alpha Piper oil rig fire in the North Sea, the King's Cross tube station fire and the 1989 Hillsborough disaster - knowing so many people had been helped financially.
"He often gave talks about it to Probus and luncheon clubs."
A funeral service is to take place at St Margaret's Church, Ilkley, on Wednesday, May 3, at 2.30pm.
A collection is being made for Sue Ryder Manorlands hospice.


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Dr. Robin Overstreet, longtime scientist at the University of Southern Mississippi's Gulf Coast Research Laboratory, is being featured as part of a special series on influential researchers at the lab who are retiring or near retirement. Overstreet, who has been part of the GCRL faculty for more than 40 years, is considered by many to be the premier aquatic parasitologist in the world. He is the third GCRL scientist to be featured in the series "Pioneers in Marine and Fisheries Research at the Gulf Coast Research Laboratory."
Overstreet, who was born in Eugene, Ore., served in the Navy before attending the University of Oregon for his undergraduate degree and eventually ending up across the country at what is now the Rosenstiel School of Marine and Atmospheric Science (RSMAS) at the University of Miami.
It was 1968 when Overstreet first visited GCRL and recognized an opportunity to set up a world-class marine parasitology research lab.


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BATON ROUGE, La. — Louisiana corrections officials want a federal judge to reduce the nearly $890,000 that a team of lawyers is requesting in a lawsuit over hot conditions on death row at the Louisiana State Penitentiary.
The Advocate reports the attorneys for Elzie Ball, Nathaniel Code and James Magee are asking Chief U.S. District Judge Brian Jackson to order the state to pay the attorneys $795,550 in fees and another $92,000-plus in costs.
Lawyers for the state claim in court documents that the billing records for the inmates attorneys are "compromised by vague entries, imprecise record-keeping, duplicative work and unreasonable time expended without adequate justification."
The judge has given the inmates' attorneys until Jan. 13 to respond to the state's opposition.
Source: nola.com, December 30, 2015
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We have 1 clues and 2 related crossword answer for Half-pipe move. Read below for answers to clues including Half-pipe move with a tail "pop and Half-pipe move.
|Last seen
|Half-pipe move with a tail "pop
|September 25, 2013
|Half-pipe move
|October 28, 2011
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Accommodations in CravinhosSee All
Planning a vacation to Cravinhos in Brazil? This vacation planner will provide you with all the essential information you need. A holiday in Cravinhos can generally be of 1-2 days.
Cravinhos is an affair to remember, follow this apt itinerary of the place and return home with a bunch of memories.
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