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McAllister, Indians edge RaysJul 17, 2012 - 6:12 AM
McAllister (4-1) won his third straight decision as he gave up just one run on three hits for the Indians, who had lost three of four coming in. Shin-Soo Choo went 2-for-4 with an RBI and two runs scored while Jason Kipnis added two hits and an RBI.
"McAllister started the game a little shaky," Acta said. "Then he got into a very good groove. It was a terrific recovery after the way he started."
Desmond Jennings hit a solo home run while Jeff Keppinger drove in the other run for the Rays, who have lost six of their last nine. Alex Cobb (4-6) lasted just 3 1/3 innings in the start as he gave up three runs -- two earned -- on five hits with five walks and three strikeouts.
"Learn to fight when things are tough and go into the next outing with a positive outlook," Cobb said of his rough start.
Choo hit a fly ball off the top of the wall in center field to start the game and it was initially ruled a home run, but an umpire review resulted in the homer being overturned and Choo was given a double. He then moved to third on a groundout by Asdrubal Cabrera and, after being held at third on a Kipnis groundout, came home on a passed ball charged to Jose Molina.
The third inning saw Cleveland plate two more runs. Johnny Damon doubled to start the inning and came home when Choo followed with his second double in as many at-bats. Kipnis then hit a two-bagger two batters later for a 3-0 lead.
Tampa didn't get its first hit of the game until B.J. Upton singled to start the fourth. Luke Scott followed with a single to put runners at the corners and Keppinger followed with a line drive off the right elbow of McAllister to score a run.
McAllister appeared to be a bit shaken up on the play, but after a few warmup pitches, he got Jennings to hit into a double play and induced a groundout from Molina to end the inning.
Jennings cut the deficit in half on the first pitch of the seventh as he crushed a fastball deep over the left field wall for his sixth homer of the year.
Esmil Rogers, who began the inning on the mound, then set down the next two batters, but walked Will Rhymes. Tony Sipp then took the hill and walked Sean Rodriguez, prompting yet another change as Vinnie Pestano came out. He was able to get out of the jam by striking out Ben Zobrist to end the inning.
Pestano stayed on for the eighth and had to get out of another tough spot. After striking out Upton to start the frame, Scott singled and quickly stole second. After Keppinger flied out, Jennings beat out an infield single to put runners on the corners. Brooks Conrad then worked the count full, but Pestano froze him with a slider for the strikeout looking.
Chris Perez worked a 1-2-3 ninth, striking out Hideki Matsui looking to end the game and pick up his 26th save of the season.
Game Notes
Cleveland center fielder Michael Brantley went 0-for-1 with three walks to have his 13-game hitting streak stopped...Five Tampa relievers pitched 5 2/3 innings of three-hit, three-walk ball...The Rays left nine men on base while the Indians stranded eight...These teams split a four-game series in Cleveland heading into the All-Star break.
- Evan Nice, Indians hold on....
Indians 3, Rays 2 FinalJul 16 10:49 PM
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- Desmond Jennings lead-off Home Run (6) to left. Jose Molina due up.
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Indians 3, Rays 1 Top 6, 0 OutsJul 16 9:20 PM
- Desmond Jennings grounded into a double play, second to short to first. Jeff Keppinger out at second. Luke Scott advances to third. Runner on third with two outs and Jose Molina due up.
Indians 3, Rays 1 Bot 4, 2 OutsJul 16 8:57 PM
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- Michael Brantley walked. Runners on first and second with one out and Jose Lopez due up.
Indians 3, Rays 0 Top 3, 1 OutJul 16 8:12 PM
- Shin-Soo Choo doubled to left scored Johnny Damon. Runner on second with none out and Asdrubal Cabrera due up.
Indians 2, Rays 0 Top 3, 0 OutsJul 16 8:01 PM
- Jose Molina passed ball scored Shin-Soo Choo. None on with two outs and Michael Brantley at the plate.
Indians 1, Rays 0 Top 1, 2 OutsJul 16 7:21 PM
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Indians vs. RaysMar 13 11:47 AM
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The Color Purple- Alice Walker
" I think it pisses God off if you walk by the color purple in the field somewhere and don't notice it. People think pleasing God is all God cares about. But any fool living in the world can see it always trying to please us back".
COLOR PURPLE, THE (1985). Photography. Encyclopædia Britannica ImageQuest. Web. 22 May 2015.
(Own paragraph written)
The Story takes place in rural Georgia, where Celie grows up in, writing letters to God and her sister, Nettie, who she hopes to find once again.
The Color Purple, by Alice Walker, was an admirable book full of twists and turns that kept me reading til the end. It was an emotional and sad life of a young girl growing up with abuses being made to her, which was written very detailed by the author. The series of letters were written in a different style, in which it was hard to understand what was happening in the first few chapters, along with the idea that an uneducated girl was writing it, so it would have many grammar mistakes in it. I had to keep reading and look for clues to find the concept that was occurring throughout the book. Overall, it was a beautiful story and I would recommend it to other people.
COLOR PURPLE, THE (1985). Photography. Encyclopædia Britannica ImageQuest. Web. 22 May 2015.

subset: commoncrawl


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Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.
Finding flights from Kaliningrad is easy with Orbitz.com. This city is serviced by Khrabrovo Airport, which is located in Kaliningrad, Russia. The airport is approximately 15 miles from the downtown area of the city and has flights from airlines such as Aeroflot, Air Berlin, Belavia, Uzbekistan Airways. You can easily find low-cost flights from Kaliningrad on Orbitz.com.
Passengers can use the services of a number of transportation companies to get to Khrabrovo Airport. These companies include taxicabs and hotel shuttles. Allo Taxi, Grad Taxi, Regata Taxi, the Renaissance Hotel shuttle and Turtle Hotel shuttle all provide rides to the airport. The city also has a public bus system that transports passengers to and from the airport. The #128 bus makes its way to the airport once every hour.
There are both long-term and short-term parking lots available at the airport. Passengers can also take advantage of off-site parking arrangements. There are a number of parking lot companies and hotels that offer parking spaces close to the airport. Most of these companies and hotels are at least half the price and provide free shuttle services.
Khrabrovo Airport passengers can choose from a number of on-site food options. There are several places to eat and drink throughout the airport, including a grocery store on the second floor. Let Orbitz.com make life easier by finding you flights from Kaliningrad.
The city of Dubai possesses the largest population in the United Arab Emirates. Located on the coastline of the Persian Gulf, Dubai has become a popular destination for tourists from around the world. Using Orbitz.com, you can find cheap flights to Dubai year-round and fly into the Dubai International Airport to enjoy everything this international tourist attraction has to offer. The airport is used by more than 130 airlines, which arrive from more than 200 locations worldwide. The airlines operating out of Dubai include Aeroflot, Air India, Cathay Pacific, Delta Air Lines, British Airways and Air France. The airport is conveniently located only 2.5 miles from the city.
Taxis are the primary method for traveling from the airport to a final destination in Dubai. Dubai Transport taxis provide metered rides into the city starting at about $5.50, with the total cost depending on the destination. Hotels in the area also offer transportation from the airport for their guests. Buses run regular routes throughout the city, servicing most of the hotels within the city center, and an automated train runs at 10-minute intervals between all 10 stations in the city. If taking the train, you'll be limited to only two pieces of luggage.
Dubai enjoys a hot and arid climate throughout the year. During the summers, temperatures average between 80 degrees Fahrenheit at night and 108 degrees during the day. Winter provides some escape from the intense summer heat, with temperatures running between 57 degrees at night and 73 degrees in the daytime. Clothing during the summer should be very light and airy to handle both the heat and humidity of the city. During the winter, a light jacket may be required for colder nights.
Dubai is a growing city and features a variety of events that attract a large number of tourists each year. The city prides itself on having some of the world's premiere attractions, such as the Dubai Airshow, which is held each year as one of the world's largest aerospace exhibitions. The Race to Dubai is the world's richest golf tournament, while the Dubai World Cup is the world's richest horserace. A large number of shops are also available, providing a place to enjoy your savings from the low fare on cheap flights to Dubai that you reserve through Orbitz.com.
Explore Dubai with Orbitz's Travel Guides to find the best flights, cars, vacation packages and more!
Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.
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Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.


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This quest is not available in game.
Reach level 3 to learn Moonfire, then use it against a Bloodfang Worgen.
- Practice Moonfire
- Learn Spell: Reach Level 3 to Learn Moonfire
We were driven to the edge of extinction once before, <name>. But we druids, keepers of the old ways, saved our people from famine.
When we cut ourselves off from the outside world and our crops failed, it was our order who called upon the earth's blessings and restored the harvest.
Just as our powers restored the crops, your growth in power will develop your connection to our ancient arts. Go, develop your powers, and use what you learn against the Bloodfang Worgen.
You will also receive:
- 75 reputation with Gilneas


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Regional Sales Manager
Our client, a national service company is looking to recruit an ambitious, articulate and efficient Regional Sales Manager. Reporting to the Directors, you will cover a wide area covering the North, North West and Midlands. Duties will include: source and maximise existing customer accounts and continually generate new opportunities in line with the company's sales strategy and performance targets, function as part of a team but in an independent, self-motivating capacity with a large amount of responsibility for the territory, you must be a first rate communicator, hold a full UK driving licence, an established Sales Professional ideally living within the assigned territory with demonstrable experience of both developing new business and growing existing accounts, a technical sales background within IT / AV / Unified Communications would be an advantage. This position would suit a sales driven professional, who is eager to grow their territory and subsequently their career and earning potential. This is a senior appointment and will offer an excellent opportunity within a dynamic and growing organisation. In return the company will offer a competitive salary with an uncapped commission structure, fully expensed company car (typically BMW 318d) and private healthcare. This job was originally posted as www.totaljobs.com/job/66677768


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Smoking behavior has been associated in two independent European cohorts with the most common Caucasian human leukocyte antigen (HLA) haplotype (A1-B8-DR3). We aimed to test whether polymorphic members of the two odorant receptor (OR) clusters within the extended HLA complex might be responsible for the observed association, by genotyping a cohort of Hungarian women in which the mentioned association had been found. One hundred and eighty HLA haplotypes from Centre d'Etude du Polymorphisme Humain families were analyzed in silico to identify single-nucleotide polymorphisms (SNPs) within OR genes that are in linkage disequilibrium with the A1-B8-DR3 haplotype, as well as with two other haplotypes indirectly linked to smoking behavior. A nonsynonymous SNP within the OR12D3 gene (rs3749971T) was found to be linked to the A1-B8-DR3 haplotype. This polymorphism leads to a 97Thr → Ile exchange that affects a putative ligand binding region of the OR12D3 protein. Smoking was found to be associated in the Hungarian cohort with the rs3749971T allele (p = 1.05×10−2), with higher significance than with A1-B8-DR3 (p = 2.38×10−2). Our results link smoking to a distinct OR allele, and demonstrate that the rs3749971T polymorphism is associated with the HLA haplotype-dependent differential recognition of cigarette smoke components, at least among Caucasian women.
There were nearly 1.3 billion smokers worldwide in the year 2003, and this number is expected to rise to 1.7 billion (~1.2 billion males and 500 million females) by 2025, with the number of female smokers contributing most to the increase (American Cancer Society, 2003). In nearly all investigated regions of the world, the ratio of female to male smokers among young people was found to be higher than the ratio among adults, suggesting a global trend for an increase in smoking habits among female adolescents and young women (Global Youth Tobacco Survey Collaborating Group, 2003). Smoking is associated with many serious health problems, including cancer of various organs, coronary artery disease, as well as several autoimmune disorders (Hegediüs et al., 2004; Klareskog et al., 2006; Warren et al., 2006; American Cancer Society, 2007; Koch et al., 2007; Hawkes, 2007), and it is thus considered a leading cause of death and disability worldwide. Although there is general agreement that nicotine is the core addictive component of cigarette smoke (Jarvis, 2004), there are hundreds of further substances that may influence the initiation and continuation of tobacco abuse (Baker et al., 2004), independent of nicotine (Franklin et al., 2007). Smoking is also modulated by genetic factors, as demonstrated by epidemiological and twin studies (Sullivan and Kendler, 1999; Li et al., 2003). In support, a haplotype of the major histocompatibility (human leukocyte antigen, HLA) complex was found to be associated with smoking behavior, stronger in women (odds ratio: 13.6) than in men (odds ratio: 2.79) (Füst et al., 2004). This haplotype, –HLA-A1-B8-DR3–, the most common among Caucasians (Alper et al., 2006), is also associated with autoimmune disorders, of which some are clearly connected with tobacco abuse, such as Graves' ophthalmopathy (Weetman, 2000; Hunt et al., 2001; Hegediüs et al., 2004; Holm et al., 2005).
At least two further HLA haplotypes have also been linked to autoimmune diseases that are triggered or heavily influenced by tobacco smoking. The HLA-A3-B7-DR15 haplotype is overrepresented in individuals with multiple sclerosis (Dyment et al., 2004; Herrera et al., 2006), while HLA-DR "Shared Epitope" (SE) haplotypes are overrepresented in individuals who smoke, possess antibodies against citrullinated proteins, and suffer from rheumatoid arthritis (Klareskog et al., 2006; Linn-Rasker et al., 2006). SE haplotypes are characterized by the presence of the HLA-DRB1*01, -DRB1*04, or -DRB1*10 alleles.
The exceptionally strong linkage disequilibrium (LD) that is typical for certain haplotypes of the xHLA encompasses a chromosomal segment with a length of about 7 Mb between the gene HFE and loci within the HLA class II region (Horton et al., 2004). In case of the A1-B8-DR3 haplotype, LD is extreme over its entire length (Alper et al., 2006), suggesting that an allele of any genes within the region of LD could in principle predispose to smoking. Therefore, polymorphic members of the two odorant receptor (OR) gene clusters within the telomeric xHLA (Ehlers et al., 2000; Younger et al., 2001; Ziegler and Uchańska-Ziegler, 2006) must be considered as plausible candidate genes.
The Centre d'Etude du Polymorphisme Humain (CEPH) panel of families (Miretti et al., 2005) offers unique opportunities for genetic association studies comprising the HLA region. The samples analyzed here comprise 180 founder chromosome 6 that have already been analyzed with regard to their single-nucleotide polymorphism (SNP) alleles and tagSNPs (representative SNPs for a genomic region exhibiting high LD) (Miretti et al., 2005). Recently, the analysis has been extended to both OR gene clusters at the telomeric section of the xHLA, permitting the correlation with alleles within the HLA class I, II, and III regions (de Bakker et al., 2006).
The present study was conducted in two steps: (i) in silico, we aimed to identify SNP alleles within the two HLA-linked OR gene clusters that are characteristic for the HLA haplotypes mentioned before; and (ii) in vitro we wanted to test whether their possible association with tobacco abuse is stronger or weaker than the one observed with A1-B8-DR3, by genotyping a subsample of the cohort in which an association between smoking and loci at the HLA class III region had been found before.
All in silico analyses were based on xHLA high-density SNP genotyping data from 180 founder chromosome 6 from the CEPH collection (Miretti et al., 2005). Details on marker selection, CEPH subjects, and on their genotypings are given elsewhere (Miretti et al., 2005; de Bakker et al., 2006). A total of 1170 SNPs spanning the region between OR2B2 and MOG (Fig. 1) were initially considered and analyzed with regard to their allelic diversity (supplemental Fig. S1, available online at www.liebertpub.com). A list of all 1170 SNPs with their genomic coordinates is given in the supplemental Table S1 (available online at www.liebertpub.com). From this set of markers, we chose 110 tagSNPs capturing the haplotypic information from the whole genomic region. SNP tagging was performed using a pairwise tagging algorithm (de Bakker et al., 2006), as implemented in HAPLOVIEW v. 4 (Barrett et al., 2005), and considering a maximum intermarker distance of 650 kb and an LD coefficient (r2) threshold of ≥0.8. Loci with a minor allele frequency of less than 1%, those not conforming to Hardy-Weinberg equilibrium, or not reported by the dbSNP database (http://www.ncbi.nlm.nih.gov/projects/SNP) were excluded.
We tested the 110 tagSNPs characterizing the OR2B2-MOG segment for association with three groups of haplotypes (A1-B8-DR3, A3-B7-DR15, and SE), the aim being to determine which tagSNPs were characteristic for each of the three haplotype groups.
The genotyping of the SNP rs3749971 was performed by real-time PCR in a sample of 32 Hungarian female Caucasians (average age 46.75 years, ranging from 24 to 76 years), which was a subsample of a cohort in which a correlation had previously been found between smoking and loci of the HLA class III region (Füst et al., 2004). Based on LD, women who carried the C4A*Q0 (mono-S) genotype as well as the AGER-429C, HSPA1B-1267G, and TNF-308A alleles were considered carriers of the A1-B8-DR3 haplotype (Füst et al., 2004). Other genotypings of these subjects, details on registration of smoking habits, preparation of genomic DNA, as well as informed consent from the cohort have been provided before (Füst et al., 2004).
The PCR reactions were performed using a Stratagene realtime PCR instrument (Stratagene, Amsterdam, NL) with the following cycle conditions: 1 cycle of 94°C for 1 min and 80 cycles of 94°C for 20 s, 62°C for 20 s, 72°C for 30 s, and 78°C for 10 s. Fluorescence was measured during the 62°C (annealing) step. Twenty-microliter PCR reactions contained 100 ng of human genomic DNA; 1.5 pmol C- or T-specific reverse primers (details below); 3 pmol forward primer (rs3749971- For: AGCGAAGAGGATTGCAGATGGC); 2 μL Genetherm polymerase buffer; 0.7 mM each of dATP, dCTP, dGTP, and dTTP; 2 mM MgCl; and 2 U of GenTherm™ Taq Polymerase. Allele-specific primers were designed as molecular beacons (Jordens et al., 2000) (rs3749971-C: Fam-atacagcCTATATCTTTTCTAGGCTGTATBHQCAC and rs3749971-T: Hex-atacagcCTATATCTTTTCTAGGCTGTATBHQCAT), labeled either with FAM (6-carboxyfluorescein) or Hex (4,7,2′,4′,5′,7′-hexachloro-6-carboxyfluorescein), and quenched with Black Hole Quencher (BHQ™) attached to a T natively present within the primer binding site. Seven bases were added to the 5′ end (displayed in lower-case letters) to allow the formation of a 29-bp "hairpin" with the 10-bp complementary region to ensure fluorescence quenching of the unused primers. To assess the reproducibility of this genotyping approach, control DNA of seven individuals (including three CEPH samples) was typed 15 times independently, with 100% reproducibility.
Nucleotide diversity (π) was calculated as described by Nei (1987), using the software DNAsp (Rozas and Rozas, 1999). The two-sided Fisher's exact test was employed for all association analyses, with a 1% level of significance. The Bonferroni correction for multiple comparisons was applied for p-values of the in silico analyses only.
The degree of nucleotide diversity as assessed by 1170 SNPs (elicited in the supplemental Table S1) was found to be highest between the genes OR12D3 and OR10C1 (supplemental Fig. S1), including the most polymorphic loci within this cluster (Ehlers et al., 2000). The SNP diversity outside of the OR clusters did not differ substantially from that within the clusters. SNP densities within the telomeric (0.388/kb) and the centromeric OR clusters (0.877/kb) were relatively high when compared with other genomic regions (Zhao et al., 2003).
Within the panel of 180 xHLA haplotypes, 11 A1-B8-DR3, 5 A3-B7-DR15, and 59 HLA-DR SE haplotypes were found. No significant association between any of the tagSNPs and the 59 HLA-DR SE haplotypes was observed, as shown in Figure 2. A similar result was obtained with regard to the A3-B7-DR15 haplotypes, although this could be due to the low number of A3-B7-DR15 haplotypes (five) in the CEPH panel. In contrast, a significant correlation was found for 12 tagSNPs (representing 81 tagged SNPs displayed in supplemental Table S2, available online at www.liebertpub.com) when the 11 A1-B8-DR3 haplotypes were compared with the 169 non-A1-B8-DR3 haplotypes for association with the 110 tagSNPs (Fig. 2), and after setting a Bonferroni cutoff for multiple comparisons. Only one of the 81 captured SNPs is a coding, nonsynonymous SNP (rs3749971, tagged by tagSNP #51), within the gene OR12D3. In A1-B8-DR3 haplotypes, the respective allele (rs3749971T) is responsible for a Thr→Ile exchange at amino acid position 97 within the OR12D3 protein. The remaining 80 SNPs lead either to synonymous exchanges or are located in intergenic or in intronic regions. Because none of these are, to our knowledge, directly involved in any, so far known, biological process, they were not considered further.
Since the A1-B8-DR3 haplotype was reported in another independent European cohorts to be overrepresented in smokers (Icelandic sample, Füst et al., 2004), and is also associated with various autoimmune diseases, of which some correlate with this behavioral trait, as in Graves' disease (Hegediüs et al., 2004; Holm et al., 2005), this data demonstrate that these associations must also extend to the A1-B8-DR3-associated rs3749971T allele.
In order to validate this finding, comparing it to the previously found association, we genotyped rs3749971 in 32 female individuals from the same Hungarian cohort (Füst et al., 2004). These individuals differ in their smoking behavior and do not suffer from any autoimmune disease (Füst et al., 2004). Here we found that the correlation between smoking and rs3749971T was slightly stronger (p = 1.05×10−2, Fig. 3b) than the correlation between this trait and A1-B8-DR3 (p = 2.38×10−2, Fig. 3c). Seven and 25 subjects were rs3749971C/T and rs3749971C/C carriers, respectively. A strong association (p = 5.87×10−4) between the rs3749971T allele and the A1-B8-DR3 haplotype was observed, as five out of seven of the rs3749971T carriers but only 1/25 of the noncarriers were found to be A1-B8-DR3 positive (Fig. 3d). The group of rs3749971C/C carriers includes both smokers and nonsmokers, as shown in Figure 3a and b.
HLA-A1-positive individuals, in contrast to those with HLA-A2 or HLA-A3, have been reported to exhibit a preference for the odor of bergamot (Milinski and Wedekind, 2001). The existence of a relationship between rs3749971T (or OR12D397Ile) and this predilection for a perfume ingredient is supported by the strong LD between HLA-A1 and rs3749971T that is described here. The fact that many tobacco brands are scented with bergamot oil components (Baker et al., 2004) provides a plausible explanation for the correlation of rs3749971T with smoking, and the identification of OR12D397Ile ligands will facilitate the design of volatiles that might be used as antidotes in individuals with a predisposition to tobacco abuse. The exchange of the hydrophilic amino acid threonine by isoleucine, a residue with a hydrophobic side chain, is expected to alter the physicochemical properties of the OR12D3 protein. However, as no X-ray crystallographic studies of ORs have been reported to date, the likely location of 97Ile within the OR12D3 protein can only be inferred from models (Man et al., 2004; Katada et al., 2005; Abaffy et al., 2007; Schmiedeberg et al., 2007) that take the structure of rhodopsin (Palczewski et al., 2000) into account. Such models locate residue 97 at the end of the first extracellular loop or at the beginning of the third transmembrane domain, close to the ligand binding site. Keller et al. (2007) have recently demonstrated that a variant of an OR gene can substantially influence sensitivity (in both intensity and pleasantness) to specific odors in humans. They showed that a mutant allele of the OR7D4 gene encoding an OR with two amino acid substitutions (residues 88 and 133) as compared to the most common allele causes functional impairment of the receptor in vitro. These substitutions also alter the perception of the smell of androstenone and androstadienone in a significant manner. Residues 88 and 133 are located within the first extracellular and the second intracellular loop. At least residue 88 is close to the beginning of the third transmembrane domain, suggesting that the region in the vicinity of residue 97 in the OR12D3 protein might indeed be involved in ligand binding. Further support for a role of amino acids close to the residue 97 in ligand binding is provided by the recently published crystal structure of the human β2 adrenergic G-protein-coupled receptor (Rasmussen et al., 2007).
Apart from social and psychological factors (Pomerleau et al., 1992; Barman et al., 2004; Lerer et al., 2006), it has been shown that the individual genetic constitution plays a role in initiating and continuing tobacco consumption (Sullivan and Kendler, 1999; Li et al., 2003). Genes within the xHLA contribute as well, as suggested by the finding of an HLA haplotype-dependent association of smoking in two independent European cohorts, with a clear-cut gender bias toward females (Füst et al., 2004). The present study confirms these results by identifying an HLA-linked OR allele that is associated with tobacco abuse. In addition, our work implies that the rs3749971T allele is involved in the smoking-induced aggravation of certain autoimmune diseases that can be observed in patients carrying A1-B8-DR3 (Hegediüs et al., 2004; Holm et al., 2005). Given the fact that the A1-B8-DR3 haplotype occurs with a frequency of 5-10% in Caucasians (Alper et al., 2006), the rs3749971 polymorphism should be suitable for large-scale screening tests, particularly among young people. Studies of the isolated OR12D3 protein will be indispensable to evaluate the consequences of the Thr97Ile exchange within this receptor on its ligand specificity.
This work was supported by the Berliner Krebsgesellschaft and by the Senate of Berlin (Ernst-von-Leyden and NaFöG fellowships to P.S.C.S.), by the Wellcome Trust (R.H., M.M. and S.B) as well as by the Monika Kutzner-Stiftung Berlin, and by the National Office for Research and Technology, Hungary.
Disclosure Statement
The authors declare that no competing interests exist.
PubMed Central Canada is a service of the Canadian Institutes of Health Research (CIHR) working in partnership with the National Research Council's national science library in cooperation with the National Center for Biotechnology Information at the U.S. National Library of Medicine(NCBI/NLM). It includes content provided to the PubMed Central International archive by participating publishers.


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Lorelei Lee – The Brutal Submission of Barbarella
Released: May 9, 2014
Part 5 of Barbarella lands Lorelei Lee on planet Sex and Submission where she submits to unforgiving bondage and merciless rough sex! In this very intense scene, Lorelei pushes her limits and shows that she is still one of the hottest and toughest girls in the BDSM world. She endures the physical challenge of the "Wall Stockade" the helplessness of a Japanese rope suspension and the vulnerable display of a wide leg spread position all while Ramon goes to town fucking and pulverizing her pussy, ass hole and mouth!


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Common Street Drugs Part 2: Meth, Weed, Heroin
Common Street Drugs Part 2: Meth, Weed, Heroin This part 2 follow up discusses 3 more dangerous street drugs that are commonly being used in the U.S. today. Although awareness about the dangers of drug abuse has grown considerably over the last few decades, the problem of addiction continues to exist and, in some cases, is on the increase. Meth, Heroin, and Marijuana are spoken about in the news often. With prescription painkiller addictions turning into street heroin addictions on the rise throughout the entire...Read More
Common Street Drugs Part 1: Oxy, Cocaine, Mushrooms
Common Street Drugs Part 1: Oxy, Cocaine, Mushrooms A recent article published by USA today states some quick, hard facts about 6 common street drugs in Wisconsin. But the information discussed is true for most of the US. These drugs make up the more dangerous and prevalent substances that law enforcement have been concerned about recently. The first 3, discussed here, include Oxycontin, mushrooms, and cocaine. The latter 3 will be discussed in a later blog – part 2. OxyContin – what is it made of and...Read More


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Description: Here is the remarkable true story of the real Count of Monte Cristo – a stunning feat of historical sleuthing that brings to life the forgotten hero who inspired such classics as The Count of Monte Cristo and The Three Musketeers.The real-life protagonist of The Black Count, General Alex Dumas, is a man almost unknown today yet with a story that is strikingly familiar, because his son, the novelist Alexandre Dumas, used it to create some of the best loved heroes of literature.Yet, hidden behind these swashbuckling adventures was an even more incredible secret: the real hero was the son of a black slave -- who rose higher in the white world than any man of his race would before our own time. Born in Saint-Domingue (now Haiti), Alex Dumas was briefly sold into bondage but made his way to Paris where he was schooled as a sword-fighting member of the French aristocracy. Enlisting as a private, he rose to command armies at the height of the Revolution, in an audacious campaign across Europe and the Middle East – until he met an implacable enemy he could not defeat.The Black Count is simultaneously a riveting adventure story, a lushly textured evocation of 18th-century France, and a window into the modern world's first multi-racial society. But it is also a heartbreaking story of the enduring bonds of love between a father and son. From the Hardcover edition.
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List price: $18.00Publisher: Crown/ArchetypePublication date: 5/14/2013Binding: PaperbackPages: 432Size: 5.25" wide x 8.00" long x 1.25" tall Weight: 1.056Language: English
Tom Reiss is the author of the bestsellers The Orientalist and The Black Count. His biographical pieces have appeared The New Yorker, The New York Times and other publications.
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George Clooney's best friend talks about his breakup with Elisabetta Canalis
Manuele Malenotti, one of George Clooney's best friends, has confirmed that the actor separated from girlfriend Elisabetta Canalis as because he didn't want to marry and have children.
"I always knew that it wouldn't last," Manuele told Chi magazine.
"To be honest I was expecting it," he says. "All I can say is that George, when it comes to love, has decided that he is not going to get married again and he is not going to have any children and he won't change his mind."
Malenotti, who introduced the couple two years ago at a dinner, also dismissed rumors that the eternal bachelor was gay and that his relationship with the model was simulated.
"I introduced them, I saw them together and I can say that their love story was very intense. In two years they shared numerous moments," he explains.
"He opened the doors of his life to her, introducing her to his friends and family. I totally exclude that it was all made up…I have spent a lot of time with him and a lot of women have passed through his life. You never know in life, and men are having an identity crisis but I can tell you George is not gay."
His best friend also said that the couple's separation came after an altercation at George's home in Italy, following an interview by Elisabetta where she said that marriage could soon take place.
"Big stars like George need people by their side to help them and they are always under immense pressure. For a partner it's never easy because everybody has their own requirements," he said.


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Equality State
- PFEATURE: Ungulate Uncertaintyplanetjh.com
- Budget cuts mean districts must make tough decisionsthesheridanpress.com
- Jennings' bathroom bill 'ludicrous, shameful'thesheridanpress.com
- Turbine technology generates opportunity, controversy in Wyomingthesheridanpress.com
- BYU football: Love or hate? Reunion with Wyoming in bowl game will feature bothThe Salt Lake Tribune
- LGBT group offers support, aims for equalitythesheridanpress.com
- PFEATURE: It happens hereplanetjh.comUnited States , Texas , Austin , Teton , Wyoming
- Visit a Wyoming State Park this summerthesheridanpress.com
- Trump May Soon Discover Independent Campaign Is His Only Option Leftnysun.com
- Cruz looks for Wyoming sweep: Trump says system is riggedwhnt.com
- Ted Cruz looks for Wyoming sweepCNN
- Sanders and Cruz Gain GroundThe AtlanticCleveland , Pennsylvania , New York , Washington , Utah
- The 2016 U.S. Presidential Race: A Cheat SheetThe AtlanticNew York , Vermont , Wyoming , New York , Washington
- Column: Rallying for womenthesheridanpress.comMain Street , Louisiana , Utah , Wyoming , Sheridan
- PTHE BUZZ: State of the Unionplanetjh.com
- PTHEM ON US 1.20.16planetjh.comNew Hampshire , New York , Wyoming , Washington , The Oval
- Crowd marches to Wyoming Capitol to commemorate MLK Daytrib.com
- Wyoming Gay Couples Get Marriage Licensesflatheadbeacon.com
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DETROIT (AP) Police are investigating an altercation between Cleveland Cavaliers owner Dan Gilbert and a former executive of his mortgage company during a private function at a posh hotel in suburban Detroit.
Birmingham police are looking into the March 21 incident at the Townsend Hotel, Police Chief Richard Patterson told The Associated Press on Friday.
"We've got an altercation we're investigating," Patterson said. "It's not a high-priority item, sounds like a very simple altercation. There is still some investigation to do."
It was not immediately known whether any complaints were filed.
Officials at the Townsend would not comment.
Gilbert is chair and founder of Quicken Loans, which is based in Livonia, Mich.
Hall is a former vice president of Rock Financial, a part of Quicken. For a number of years, Hall was the public face and pitchman for the company, appearing in television and radio ads. Many of those ads involved the company's sponsorship of the Detroit Pistons.
His employment with Rock Financial ended in 2007. He now runs a Birmingham-based marketing and consulting company called DHall Ventures.
There is no phone listing for the company. Hall did not immediately return e-mail messages sent by The Associated Press seeking comment.
Quicken Loans officials declined to comment Friday about the altercation, spokeswoman Elizabeth Jones said.
Gilbert and the Cavaliers also declined to comment.
The leading investor of a group that bought the Cavaliers in 2005, Gilbert has at times been outspoken as the team's majority owner.
In September, he called rampant speculation that star forward LeBron James will leave Cleveland after his contract expires in 2010 "an insult to the city."
Last month, Gilbert expressed dismay when Cavaliers' guard Mo Williams was left off the All-Star team, poking fun at the snub by using made-up words like "stupidiculous," "idillogical" and "preposterageous" to describe his feelings.
Williams was later added to the roster as a replacement for injured Toronto Raptors forward Chris Bosh.
Copyright 2009 The Associated Press. All rights reserved. This material may not be published, broadcast, rewritten or redistributed.
Guidelines: You share in the USA TODAY community, so please keep your comments smart and civil. Don't attack other readers personally, and keep your language decent. Use the "Report Abuse" button to make a difference. Read more.


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1 Indian Chase Drive - Greenwich, Connecticut
Double gates open to an alluring European Estate on 1.8 waterfront acres close to town. Spellbinding setting, high above Indian Harbor & Long Island Sound. Front-to-back, gallery, living room, library, solarium, family room and formal dining room feature lofty ceilings, herringbone floors, stained & leaded glass windows. Gaggenau kitchen with serving area, informal dining area, powder room and access to upper suites and elegant sitting room, fireplace, paneled office, game room, gym, sauna, steam room & staff quarters on lower level. 200 bottle wine room. Marble stairs to master wing with sun terrace, 2 wardrobe closets and luxury bath featuring two steam showers and spa tub. Established gardens, fountain, woodlands, pool, spa, dock/boat house, tennis court and 800 s.f. carriage house.
This listing courtesy of Douglas Elliman
M: email@example.com
M: firstname.lastname@example.com


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French Connection wool-blend jacket is a timeless piece for your wardrobe. Wear it with matching trousers and a striped shirt for modern gentlemanly attire.
Dollar Herringbone Jacket features a peaked lapel, chest pocket, two flap pockets and is single-breasted with a single button fastening. Jacket is lined and features side vents.
Style code
* Dry Clean Only
* 50% Wool 50% Polyester
* Length from centre back; 73.5cm


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Perfect for a world traveler or an aspiring one, this striking round wall clock adds style to any room in the home. Featuring bold Roman numerals with New York, London, Tokyo, Paris and Berlin are called out in the center in bold letters. Constructed in metal and completed in a black finish with gray wash, this wall clock enhances any style of decor. From Cooper Classics.
Third generation family owned and operated Cooper Classics is known for their trend-setting line of mirrors and home accessories. The company's headquarters and factory are located in the USA in the beautiful Blue Ridge Mountains of Virginia. Browse their collection for modern wood mirrors, contemporary clocks for the kitchen and more.
Our team has over 100 years combined experience with contemporary lighting.
Every EuroStyleLighting.com order is backed by our 100% Satisfaction Pledge.
Shipping and Delivery Information - For item EU1J026 if ordered by 1 pm Pacific Time


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Haverhill Wellness
Home | Wellness Committee | Staff Directory | Substance Abuse Education
Health & Physical Education | Athletics | Resources
HPS Health & Physical Education Brochure
Wellness Newsletter April 2016
Public Records Request InformationGet information on public records request and information on Massachusetts public records law.The New Haverhill Public Schools AppGet the latest news and sports scores from around the district. Customize the app to only view specific schools and their calendars. Click here to download iOS or Android versions.Crisis and Emergency Preparedness for Parents/GuardiansView PDFs here about Crisis and Emergency Preparations


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- Return to Touhou Soccer Moushuuden
Special Technique Unlocks
Note that the techniques will only unlock for Main scenario and travel mode after you finish the ENTIRE subscenario.
Aya's Scenario
- Thunderclap Gale (Aya): Have Aya receive an air ball in enemy's penalty zone during match 4.
- Enhanced Phantasm, Foam and Shadow (Yukari, Ran, Chen): Have Anyone of the Yakumo clan receive an air ball in your penalty zone during the second half of match 4.
Reimu's Scenario
- Frozen Sword (Saito): Attempt to 1v1 against him during match 1 with anyone.
Marisa's Scenario
- Twilight Spark (Mima): Have Mima receive a ground ball (either dribble into, or receive an air ball and chooses to Trap) in enemy's penalty zone at least once during both halves of match 4.
Cirno's Scenario
- Spiral Interception (Daiyousei): Either chooses to intercept when Daiyousei encounters someone, or have her automatically intercept.
- Minus ➈(Cirno, Letty): Cirno receives a cross during second half.
Rumia's Scenario
- Twilight Flight Dance (Rumia, Mystia): Have either Rumia or Mystia receive an air ball in opponent's penalty zone during match 2.
Hong Meiling's Scenario
- Quad Spark (Patchouli): Have Patchy attempts an 1v1 during match 1.
- Flying Dragon Fist (Meiling): Have Meiling receive a ground ball in enemy's penalty zone during match 3.
Sakuya's Scenario
- Game of Rising (Eirin, Sakuya): Have either Eirin or Sakuya receive a ground ball in enemy's penalty zone during match 3.
- True Flying Knee Kick (KoakumaGK): Have an opponent receive an airball near your goal during second half of match 3. If Koakuma is given the option to jump, she will automatically use it and learn it. (Probably the most difficult one to unlock)
Flandre's Scenario
- Topspin Pass (Koakuma): Have Koakuma pass to anyone.
- Transylvania (Flandre, Remilia): Have either Remilia or Flandre receive an air ball in enemy's penalty zone during match 3.
Alice's Scenario
- Shanghai Doll (Alice): Automatically learned before match 2.
- Doll Mira Ceti (Alice): Automatically learned before match 4.
- Red Magic, White Magic, Purple Magic, Yellow Magic, Green Magic (Alice-98): All automatically learned before match 5.
- Poison Doll's War(Alice, Medicine): Have either Alice or Medicine receive an air ball in enemy's penaty zone during match 5.
Youmu's Scenario
- Artistic Dribble (Youmu): Automatically learned before match 1.
- Lobbing Shot (Tewi): Allow Tewi to attempt an 1v1 during match 1.
- Blooming Red-Eyed Konpaku the 2nd (Reisen, Youmu): Have either Youmu or Reisen receive an air ball in your opponent's penalty zone during match 3.
Lilies' Scenario
- Rainbow Pass (Lily White), Spring Breeze (Lily Black): Automatically learned before the match..
- Lethal Twin (Lily White, Lily Black): Have either Lily receive an air ball in opponent's penalty zone during second half.
Game Freezes
The game will sometimes freeze during matches before movie animations. Updating the game will prevent most of the freezes.
Game Freezes at the beginning of the Main Scenario
To prevent that, turn BGM OFF in Options Menu.
- Return to Touhou Soccer Moushuuden


text: Advertisement Skip the ad in 0 sec Skip Ad Savory Cupcakes Cupcakes 8 of 9 Photo courtesy of Cecelia Henricks The Lox Mona Wilson of It's a Cupcake in Philadelphia doesn't shy away from using seafood in her savory cupcakes—her ingredients range from shrimp and tuna to oysters and lobster. For The Lox (pictured), she tops a scallion cake with smoked salmon chive cream cheese. SEE MORE Satisfying savory cupcakes, from a veggie curry variation to the indulgent bacon white truffle.


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We're a cosy family pub in the heart of Whitstable, just a stone's throw away from the beach, the high street and the harbour.
You're guaranteed a warm welcome and a great atmosphere here, with a very friendly team dedicated to making sure you have a great time!
Inside, you'll find a beautiful bar with a cosy fireplace for those chilly nights. Outside, we have a great beach-like beer garden for warmer times.
If you're looking for delicious traditional pub food at great prices, you'll find it here. We also serve great ales (come and join our fabulous Real Ale Club - 50p off any pint of ale every Tuesday from 5pm), ciders and wines.
Music fans will love the live music performances here, with a variety of styles to meet everyone's tastes.
Come over and see us soon!


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Agency: Fallon
Client: Orange
Orange has unveiled a new global brand vision and campaign to promote the company's transformation into one of the world's leading providers of digital communications.
The vision, expressed in the statement: "together we can do more", will be brought to life in the company's largest ever global integrated campaign to be launched across Orange's worldwide markets starting in the U.K.
At its heart is the idea that today consumers live in a digital world where borders between people and places are being pushed away. This changes the way people connect within society letting them share ideas and collaborate to achieve more than an individual can alone.
"The Orange brand was originally developed for one technology in one market – mobile telephones in the U.K," said Caroline Mille, Senior Vice President, Brand and Communications. Orange.
"Today, just 14 years later, the brand now spans a range of technologies (internet, T.V content) and reaches consumers in 26 countries, covering very different cultures. Thanks to its global enterprise services, Orange also has operations in most markets around the world."
She added, "Since 2006 it has been the key brand of the France Telecom Group and now includes mobile, internet and TV services plus content associated with these three platforms.
"Despite this change, the brand has lost none of its strength, staying true to its original values which have become the values of the whole Group. The new brand vision allows us to truly communicate everything that Orange now stands for".
France Telecom has 170 million customers, of which are 120 million are under the Orange brand. The Orange brand was ranked 50th most valuable brand in Millward Brown's recent global brand survey, an increase of 17 places on the 2007 survey.
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Had a chance to see more than 30 countries & lived in 6 countries of 4 continents.
An Author to two books, columnist to few news papers & sites. Guest Facility to few universities
well.. I think I'm an open minded person, interested about many things in life. I'm socially sensitive meaning I look for ways of helping others in need and I also like to live an environmental friendly life. You know, to find somehow the balance in this mad consuming all day world :)
I can hardly tolerate racism and other types of discrimination.
I'm a person who is in peace with herself, I can fully feel fine being alone meaning I am usually not dependent on others to do things and reach my goals. But this of course does not mean I want to stay alone ;) I want somebody who has goals in life and who thinks that a relationship is a source to add additional happiness to your life but I do not like overly attached things - I have my own life as well and you can have yours. Somebody who enjoys simple things in life like staying in bed on a cold Sunday morning listening to the rain, just sit in silence under the stars or breathing in the smell of the wet ground in a forest. I look for somebody who makes my days even happier, who wants to share exciting adventures and be a real man next to a real woman.I love going to any water to swim or hike with the dog or just discover the city. Or just sit hours in a ruin bar discussing the big things of life :) Due to the things I experienced in life I'm tolerant and flexible and I can hardly get stressed. I know nothing lasts forever therefore I try to make the best of anything. In some aspects I'm kind of a junkie type :)
I run my own business, that requires a lot travel around world.
I write on social issues, and finishing my next book to publish.


text: Posted February 27, 2013 lots of rumors flying around that the 9ers might target Harvin or Revis. With all of those picks it certainly seems possible. Furthermore, a lot of their picks didn't even play last year. they can essentially skip out on this year's draft (by trading for established players or by trading for future picks) and not even take a hit in terms of performance. Mother fuging poo. Alex Smith a 2nd and a 3rd, are you serious? I Dno about Revis but can def see a Harvin trade. SF read option will only be more problematic for opponents with Harvin in the mix. Vikings will def bite on a 2nd rd offer. Share this post Link to post Share on other sites


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As the first international anthology of Filipina writers published in the United States, Babaylan reflects the complex history of a people whose roots have stretched to both sides of the globe. With contributions from over 60 Filipina and Filipina American writers, Babaylan provides readers with a comprehensive view of a growing and vibrant transnational literary culture. Challenging, innovative, fierce, reflective, somber, funny—no one word can capture the extraordinary range of this collection.
Winner of the Silver Medal in ForeWord Magazine's Anthology Category
This anthology presents the work of over 150 young inner-city poets, reflecting on their experiences with violence and sharing their desires for peace and unity in their families, in their communities, and across the globe. Each poet presents a unique perspective and voice; when read together their work becomes a powerful call for peace. Whether in the hands of educators, peace activists, poetry lovers, or other young writers, City of One is a compelling portrait of a generation of youth who use their words to re-envision the world.
This collection of essays, poetry, and artwork brings together scholarly and creative responses inspired by the life and work of Gloria Anzaldúa. The diverse voices represented in this collection are gathered from the 2007 national conference and 2009 international conference of the Society for the Study of Gloria Anzaldúa (SSGA). More than 30 scholars, activists, poets, and artists contributed to El Mundo Zurdo, whose release coincides with the SSGA's second annual international conference in San Antonio, Texas.
Aunt Lute Books is excited to announce the publication of El Mundo Zurdo 4, the newest collection of diverse essays and poetry that offer scholarly and creative responses inspired by the life and work of Gloria Anzaldúa, selected from the 2013 meeting of The Society for the Study of Gloria Anzaldúa.
Aunt Lute Books is excited to announce the publication of El Mundo Zurdo 5, the newest collection of diverse essays and poetry that offer scholarly and creative responses inspired by the life and work of Gloria Anzaldúa, selected from the 2015 meeting of The Society for the Study of Gloria Anzaldúa.
In homage to Gloria Anzaldúa and her iconic work Borderlands/La Frontera, award-winning poets ire'ne lara silva and Dan Vera have assembled the work of 54 writers who reflect on the complex terrain—the deeply felt psychic, social, and geopolitical borderlands—that Anzaldúa inhabited, theorized, explored, and invented.
Winner of the Lambda Literary Award for Best Lesbian Debut
A bold collection of creative pieces and theoretical essays by women of color. Making Face/Making Soul includes over 70 works by poets, writers, artists, and activists such as Paula Gunn Allen, Norma Alarcón, Gloria Anzaldúa, Lorna Dee Cervantes, Barbara Christian, Chrystos, Sandra Cisneros, Michelle Cliff, Judith Ortiz Cofer, Elena Creef, Audre Lorde, María Lugones, Jewelle Gomez, Joy Harjo, bell hooks, June Jordan, Trinh T. Minh-ha, Janice Mirikitani, Pat Mora, Cherríe Moraga, Pat Parker, Chela Sandoval, Barbara Smith, Mitsuye Yamada, and Alice Walker.
This compilation is the first comprehensive work to focus on South Asian American and South Asian immigrant women in the U.S. It represents a pioneering effort to collect the critical essays, creative works and personal histories by and about women of South Asian descent. The diverse expressions of identity and experience found here enable us to begin to see how women of South Asian origin define their positions within their respective communities, within wider interethnic networks, and within national and international social, economic, and political frameworks which impact women's lives, both in the United States and in South Asia.
One hundred years after San Francisco's Great Earthquake of 1906, WritersCorps gathers the powerful voices of San Francisco youth reflecting on solidity, violence, upheaval, and regeneration in their lives and in the world. The poems on these pages are a moving story, eloquent, fragile, courageous, and shattering.
Compiled in one book for the first time, featuring both new and out of print pieces, the contents of The Judy Grahn Reader span four decades of work by the prominent writer and activist. This volume contains writing from every phase of Judy Grahn's career, including poems from all of her major poetry collections, such as "The Common Woman," "A Woman is Talking to Death," and the previously unpublished "Mental"; a number of her groundbreaking essays ("Writing from a House of Women" and the newly revised "Ground Zero: The Rise of Lesbian Feminism," among others); as well as selected fiction and the full-length play The Queen of Swords. As Judy Grahn's writing continues to be relevant in today's social, political and cultural climate, this comprehensive volume gathers the varying strands of her writing and makes visible the tremendous scope of her ongoing contribution as a feminist thinker, activist, and literary artist.
Animal stories have been handed down through the rich oral traditions of over five hundred distinct American Indian languages and cultures, offering understanding about and guidance to the natural and social worlds. The fiction and poetry gathered in this collection honor these traditions, retelling and reshaping traditional narratives by recalling their ancient wisdom and renewing their spirit in new contexts.


text: School Home Page - Historical List of Baseball Players Standings Roster Schedule College Navigation Conferences College Basketball America East Atlantic 10 Atlantic Coast Atlantic Sun Big 12 Big East Big Sky Big South Big Ten Big West Colonial Athletic Conference USA Horizon League Ivy League MAAC Mid-Continent Mid-American MEAC Missouri Valley Mountain West Northeast Ohio Valley Patriot League Pac-10 SEC Southern Southland SWAC Sun Belt West Coast WAC Opinions News Scores/Schedule Standings Teams Players College Football Opinions News Scores/Schedule Standings Teams Players Quick Facts Athletics Logo Established: 1856 School Type: Public President/Chancellor: Dr. CD Mote Location: College Park, MD Campus Size: Medium, suburban Enrollment: 20,000+ undergraduate Faculty: Mascot: Testudo, a diamondback terrapin Stadiums: Byrd Stadium (51,500), Comcast Center (17,950) Colors: Black, red, gold, white Team Nickname: Terps Conference(s): ACC Homepage: www.umd.edu Athletic Homepage: www.umterps.com Local Radio: 630, 980, 1300 AM Basketball Ranking: RPI Rating: Football Ranking: BCS Rating: Edit These Facts Retrieved from "http://armchairgm.wikia.com/wiki/University_of_Maryland_Baseball?oldid=71466" Ad blocker interference detected! Wikia is a free-to-use site that makes money from advertising. We have a modified experience for viewers using ad blockers Wikia is not accessible if you've made further modifications. Remove the custom ad blocker rule(s) and the page will load as expected.


text:
We received our Royal Charity status in 1949 and are governed by the RNIB Royal Charter and Bye-Laws:
The RNIB Group Board of Trustees is responsible for taking the major decisions that affect our group of charities – RNIB Charity, Action for Blind People and our other Associate Charities.
Find out more about how we work together in our partners.
Including the honorary officers, we have 12 Group trustees. Ten of the trustees are blind or partially sighted.
Our trustees are:
The RNIB Charity Board of Trustees is responsible for delivering our Group Strategy along with Action for Blind People in England and Cardiff Institute of the Blind in Wales. The RNIB Charity Board of Trustees is governed by Articles of Association.
Our trustees are:
Right now we can only reach one in three of the people who need our help most. Please make a donation and help us support more blind and partially sighted people.Donate now


text:
Intro to Monetization Chat Transcript
Monday's Twitter chat discussion was an Introduction to Monetization. We began with two disclaimers: 1) monetization is a complicated topic that can only be touched upon (rather than fully covered) in one hour on Twitter and 2) you don't have to monetize your blog. Some people just blog for fun, and that is okay! We completely support that. Realize that if you do want to monetize, you'll need to do some research to figure out the avenues that are right for you. Crafterminds recommends diversifying the sources of your income so that you aren't depending on any one thing to provide you with a revenue stream. You should also proceed cautiously and make sure to read everything (such as contracts) carefully. Here are some key points from the chat:
- There are only a handful of large bloggers that make great money. The Crafterminds girls don't make close to a full-time salary, but we do make enough for extra spending money! Monetization can be a great option for your blog – just keep your expectations reasonable.
- There is no magic number of followers to indicate when you should monetize your blog. It's all up to you – you might be smaller with a loyal following; you don't have to be a huge blogger to start thinking about making money.
- Compensation can also include free product. Consider blogging about your favorite craft supplies for free or a reduced rate in exchange for the product – that product has a monetary value.
- Disclosures are legally required for paid posts. A good service for disclosures is http://cmp.ly.
- Ad networks – you typically get paid a price per thousand views (called CPM). Getting into an ad network is difficult, but Google AdSense and Project Wonderful are open and easy to integrate into your blog.
- Sponsored ads – allowing sponsors to purchase ad space on your site directly may be a good option for you, and it eliminates the ad network middleman. Keep in mind that getting sponsored ads requires some selling on your part as well as client management.
- Paid/sponsored posts – these are individual blog posts that you get compensated a set amount for. Good places for finding paid post opportunities are Clever Girls Collective and SocialSpark.
- Affiliate networks – you get paid for product purchases through your blog. Options include ejunkies, Commission Junction, Amazon Affiliates, PepperJam, ShareASale and Google Affiliates.
Thanks to all those who attended!
4 Responses to "Intro to Monetization Chat Transcript"
I wasn't able to be in the chat, but thank you for the transcript and the summary! Super helpful.
What a great chat! I'm another one who couldn't make it (due to time zones), but I learnt so much. Thank you to everyone who participates and for making the transcripts available.
Amy, I so wish you were my neighbor and I could just have you over for coffee. (hee,hee) I only understand bits and parts of this but I'm sure if I keep following your advise and reading your posts, one day I will understand it all!
- Sunday Afternoon Housewife » Blog Archive » Twitter Parties, Twitter Stats, and TweetChat for Crafters - [...] place each Monday at 4pm EST and is hosted by a rotating group of the 4 ladies behind Crafterminds.…


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If an item you ordered from TextbookRush does not meet your expectations due to an error on our part, simply fill out a return request and then return it by mail within 30 days of ordering it for a full refund of item cost.
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Description: From author ofThe Christmas Hope series, which has enthralled millions of readers, comes a new inspirational novel about an unlikely friendship between two women, but one that will change each of their lives forever. Gretchen McCray has recently moved into an apartment with her two children to be closer to her mother, Miriam. She and her children are building a life together in a new community when a mysterious young woman, Melissa Summit, moves into the apartment next to them. She has few possessions, little personality, and keeps to herself. One day, a local landlord who is looking for Melissa knocks on Gretchen's door for assistance. Melissa's mother has died and in the coming weeks the landlord needs Melissa to empty her mother's apartment. Gretchen reaches out and offers to help, but the apartment is a gut wrenching shamble of a home. There is little worth saving except for a few photos and a note that is discovered on the crate beside the bed. It is unfinished but in the two scribbled lines, Melissa discovers she has a brother and a sister that she never knew about. Even more shocking, she begins to uncover family secrets that show her who she really is. Can two very different women embark on a journey that explores a long-buried need for forgiveness, hope, and redemption?
Limited time offer:
Get the first one free! (?)
All the information you need in one place! Each Study Brief is a summary of one specific subject; facts, figures, and explanations to help you learn faster.
List price: $14.99Copyright year: 2011Publisher: St. Martin's PressPublication date: 10/25/2011Binding: HardcoverPages: 224Size: 5.37" wide x 7.39" long x 0.88" tall Weight: 0.550Language: English
Donna VanLiere has written numerous books including The Good Dream, Finding Grace, The Angels of Morgan Hill, and The Christmas Light. The Christmas Shoes and The Christmas Blessing were both adapted by CBS television into movies. She has received a Retailer's Choice Award for Fiction, a Dove Award, a Silver Angel Award, and an Audie Award for best inspirational fiction. She is also a popular conference speaker and has appeared at numerous women's and family events.
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A time capsule buried by patriots Samuel Adams and Paul Revere more than two centuries ago was unearthed Thursday in Boston.
The capsule was discovered by construction workers making repairs at the Massachusetts State House. Reports say that the box was placed there in 1795, the year construction began on the building.
"What we know the box contains, based on the notes that we have, is a Paul Revere plate, papers, and coins from the 1600s," said Massachusetts Secretary of State William Galvin, head of the state's historical commission. "It may contain other stuff too, we don't know that yet," he said.
X-rays are part of the processes being used to determine the contents before the careful task of opening the box.
"The contents are of concern, but the plaster that held the box in place is in good condition," Galvin said.


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Wildcats Begin Spring With a 2-1 Weekend
April 4, 2011
LEXINGTON, Ky. - The Kentucky volleyball team got off to a hot start in spring action with a 2-1 weekend at the KIVA Collegiate Tournament hosted in Louisville, Ky.
The Blue and White earned impressive 2-0 sweeps of Notre Dame and Morehead State. UK's lone loss was a 2-1 deficit to Purdue, an NCAA Elite Eight member from a season ago.
Kentucky was led at the net by junior Ashley Frazier who turned in a combined 22 kill performance. Seniors Becky Pavan and Ann Armes chipped in with 14 apiece in UK's first competitive action of the spring slate.
UK will return to action with a head-to-head matchup at Ohio State on Saturday, April 9. Kentucky and the Buckeyes played in a memorable match in Lexington during the 2010 season.
Lauren Rapp posted her second double-double effort of the Kentucky Classic in helping the 16th-ranked Wildcats to a 3-1 (25-17, 22-25, 27-25, 25-20) victory over previously undefeated Ohio State to win UK's tournament in late September.
Rapp tallied 12 kills and picked up 12 digs in the win. Rapp was joined on the All-Tournament team by Blaire Hiler who pitched in 10 kills and six digs. Stephanie Klefot also earned All-Tournament honors after her third double-figure dig effort of the weekend with 18 scoops in the match against Ohio State.
Christine Hartmann dished out 41 assists and added five kills of her own to lead the Wildcats to a .250 hitting clip and 55 kills on the night. Whitney Billings matched a career-high with 15 kills and Pavan chipped in with 10, while leading the team with six blocks. Gretchen Giesler came off the bench to help spark the Blue and White and she added a pair of kills and two blocks in two sets of action.
The Wildcats opened the match with a dominating 25-17 victory. Billings and Pavan combined for nine kills in the stanza as UK charted a match-high .321 hitting clip and 16 kills in the opening frame. UK's defense limited the Buckeyes to 12 kills on .128 hitting and turned back four Ohio State attacks.
Following UK's matchup with Ohio State this week, UK will travel to West Lafayette, Ind., and take on Purdue and Ball State to conclude the spring schedule.
Follow along with UKathletics.com for the most up-to-date information regarding the Kentucky volleyball team and all of UK's 22 sports.


text: SYDNEY, AUSTRALIA, March 27, 2001: The Rev. Robert Frisken of Christian Community Schools Ltd. here does not want the stories about Harry Potter, the trainee wizard, banned, but suggests the books should carry warning stickers before they are placed in school libraries. "The ordinary person is typified as being bad because they have no magic powers, and heroes are the people who are using the occult. Good finds itself in the occult, which is an inversion of morality for many Christian people." Frisken will, this month, send letters to parents in each of the 90 independent member schools across Australia asking them to consider the issues raised in the stories and discuss them with their children. The books have become a controversial addition to classrooms in America -- figures show they were the most challenged books of 1999. Efforts to restrict their use, or remove them from classrooms and school libraries were reported in 19 states.


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Mass Effect 3
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- Mass Effect 3
- Create your ideal ME4 *SPOILERS*
VirtualAnomoly 4 years ago#1
At the beginning, most of you are split up, except Commander King (Yeah, just because) and a Human. You quickly find the Turian. At the beginning, most racees of the galaxy hate you.
Throughout the game you find your other friends, until one point you can go to two planets, you find out each planet has either the Krogan or the Salarian on it (you can only save one, if Krogan died in ME3, you are forced to save the Salarian)
Your choices change how certian species view the Milky Way species, and can land you with new Alien squadmated. It is possible to end ME4 with only three people. King and two squadmates. It is also possible to end it with 8 (King, two humans, Turian, Salarian/Krogan, Quarian, Geth,New species)
ME4 ends with the relay being fixed, but at least 3 species (unless you made more than those specific 3 hate you) are still against Milky Way aliens.. (you can have the WHOLE galaxy against the milky way galaxy.) your choices can make all species like you except these canon three.
ME5-6 you build armies,relationships, weapons, ships etc to fight. It is possible to lose (especially if the whole galaxy is against you) and it is possible for Milky way to turn. (Turian/Asari/Salarians etc can join the new galaxies team if humans make them made enough, but it is possible to keep them)
Some things canon.
If Krogan died and Rachni lived, Rachni are always loyal.
If Quarians and Geth lived and you chose synth, Both are always loyal. (if only one is they are harder to defect than others)
If Krogans died and Rachni died, sucks to be you.
If Both Quarians and Geth Died, Krogans lived, and Rachni lived, Krogans and Rachni are loyal.
If Krogans lived and Wrex is in charge, they are always loyal. (IF rachni lived, they are hard to defect)
If Wreav is in charge, Krogans always defect, and Rachni always defect(unless you killed Quarians and Geth) (making it very hard)
If you sabotaged the Genophage, Salarians are always loyal.
Each squadmate from ME1-3 is mentioned like a legend. (King tells stories about Shepard, Ashley, Javik, etc Dialogue changes depending on who died where and etc)
If you chose Udina in ME1, Humans are off the council. If you chose Anderson in ME1, Humans are on the council.
If you chose to save the Quarians and not the Geth, Quarians are on the council.
So some decisions that were bad in ME1-3, are good in ME4-6.
ME4-6 also has new choices.
NOTE this is NOT real, I made it up.
If you believe in Jesus Christ as your personal Lord and Savior and are 100% proud of it, put this in your signature.
Black FC---0304 1624 6630 (cole)
My idea is this it isnt a prequel it isnt a sequel but rather something new & unique and something that has never been done before. A STORY WITHIN A STORY.
While Cmdr. Shepard is doing his/hers things we will CAC a new MC using Background Choices such as the new upcoming DA 3 will use based on these you will have a difrent character each playthrough and told through a diffrent POV.
We will visit & help out the Planets Shepard & The Normandy crew never went to and help them out and take out the Reapers on those Planets & help evacuate the Civilians and gain additonal support for Shepards Armada for the Crucible.
The Volus Homeworld, The Drell/Hanar Compact other Colonies and new places Shepard & Crew never been to we will Clean Up, Protect & Evacuate These Planets & Colonies.
I call this a new type of game it will be Inter-Connected to the Shepard Trilogy while it will yet be its own storyline with a new MC without Shepard but the Choices our MC make will Effect the original Shepard Trilogy.
My game would change the ending and add new elements to the Shepard Trilogy via this games Import you could import this game into the Shepard Trilogy thus changing the endigs and other details making Shepard's Ending more complete.
Our MC would any race, combinations & each deal would be a Dragon Age Origins type of deal and told through a unqiue POV this game is in the Shepard Trilogy's Timeline thus you can import this game into Shepards making it the 1st of its kind to do this.
Inter-Connected A Story Within a Story not a Prequel not a Sequel this game would Reshape and make Mass Effect 3 entirely new & diffrent via this games Import based on the things we do in this game.
Mass Effect DownFall
Mass Effect - Rising Darkness
Mass Effect - End Game
Mass Effect - Dark Revelations
Mass Effect - 2nd Strike
So what do you think could this deal work a Inter-Connecting game a Story Within a Story this game would Reshape and make a Totally diffrent Mass Effect 3.
Dont get me wrong this game I am working on is Fan-Fiction fans were whining I dont want Sequel I dont want a Prequel then I came up with this idea.
A game that is neither Sequel or Prequel.
Painesnewname 4 years ago#3
A samequel!
Mass production.....?
Musou Effect.
"I'll swing by and sign the contracts, alright. Just ignore the bodies."
No offence to any ME Fans but The ME Trilogy was well done but in my opinion, Bioware needs to make something new, [new IP] is what Bioware has been doing since last-gen is what made me like them and I own every Bioware game they made except Star Wars: The Old Republic and that Sonic game they made for Nintendo DS. As much as I like ME, Bioware just need to move on and do something new for a change.
Brad Pitt, no silencer on that shotgun. How are you supposed to kill anyone softly without a silencer?
XBOX GT: Player1mj117. PSN: playmaker45.
VirtualAnomoly (Topic Creator)4 years ago#6
melvin343 posted...
No offence to any ME Fans but The ME Trilogy was well done but in my opinion, Bioware needs to make something new, [new IP] is what Bioware has been doing since last-gen is what made me like them and I own every Bioware game they made except Star Wars: The Old Republic and that Sonic game they made for Nintendo DS. As much as I like ME, Bioware just need to move on and do something new for a change.
The only reason I really disagree is because there is so much lore, it seems like it would suck for the writers to just lose it all. (Asari cheated for their advancements, could have prevented Reaper-War, never saw how the other council species took that.)
If you believe in Jesus Christ as your personal Lord and Savior and are 100% proud of it, put this in your signature.
Black FC---0304 1624 6630 (cole)
Rogue Mutt 4 years ago#7
All I really want is to be able to pick my race, gender, class, and then customize the hell out of my appearance. Maybe make it so that NPCs react differently depending on what race you are, and if possible, create different dialogue/interaction options that are race dependent also.
Maybe explain it by saying that your character is part of a task force that pulls the best personnel and tech from all corners of the galactic community. If you wanted a direct tie-in to the ME trilogy, available playable races could be dependent on who was still alive/working with you in your ME3 save.
VirtualAnomoly (Topic Creator)4 years ago#8
Rogue Mutt posted...
All I really want is to be able to pick my race, gender, class, and then customize the hell out of my appearance. Maybe make it so that NPCs react differently depending on what race you are, and if possible, create different dialogue/interaction options that are race dependent also.
It'd be cool but I prefer that for MP.
If you could make yourself
It would be really hard to make as good as a story/characters. (If Shepard was a Turian)
If you believe in Jesus Christ as your personal Lord and Savior and are 100% proud of it, put this in your signature.
Black FC---0304 1624 6630 (cole)
My game or my idea would have a CAC that is deep, & very customizable being able to use any race, diffrent combinations using a Background Selection to change the story each go around told through a diffrent POV based on these backgrounds such as how Dragon Age 3 will use Background Choices.
But in DA 3 you can only be a Human Male or Female once again such as DA 2 and once again can only be a Mage, Warrior and Rogue the only new element is the Background Choices which I assume is like Slave, Bandit, Noble or Inquistion.
My game would be similar but unlike DA 3 you would be diffrent races from Drell, Asari, Geth, and Krogan and diffrent Backgrounds to make it Unique.
Mass Effect Down Fall would be a Game Within A game yet while it is own deal would reshape & rechange Mass Effect 3 once done with Down Fall you could import Down Fall into Mass Effect 3 to make it a completly new deal with a diffrent ending based on our actions in Mass Effect Down Fall.
Another new Feature in Down Fall is new attack called Burst Fire Mode which is a powerful 2nd Alt Fire Mode for the Weapons but could only be achieved via how many kills you make on field once the meter is Filled Press the RT Button and a new powerful attack will occur.
Also new is a more robust Weapon Craft System now using the Kinect we can Take apart the weapons Using the Kinect. Finding gear and components on the field we can upgrade & modify our Weapons. But there is also a catch you can only use Weapons when you are at a certain LVL such as Snipers LVL 10, Rapid Fire, LVL 20, Heavies LVL 30, also you can not customize your weapons without the Gear & components.
I got the Weapon Idea from the Tom Clancy deal but I made my own spin on it.
Also I would add in a new 2nd Attack for Omni Weapons that would also work like Burst Fire Mode on the Weapons. I call this Mode Burst Attack Mode.
So Burst Fire for Weapons & Burst Attack for Omni and a Kinect Feature for Weapons.
Also I would use the Kinect to make our CAC use it unique like Weapons would.
I would also make a new Warship such as the Normandy was for Shepard this Ship would be for us called the SR-3 WarBreaker. It would be a lot bigger than the Normandy is. Maybe on Terms of a Cerberus Cruiser in terms of size.
Urdnot_Runt 4 years ago#10
Brand new ME story that acts as if the original trilogy never happened.
New conflict, new characters, new story.
Same visual style, same technology, same choice based system
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Angel Santiago was tapped as the man to replace Trent Steelman. I like that there was such a battle for the spot, and I like that the coaches went with the guy who has been taking better care of the football - but underneath it all I am happy to have two guys this close at the start of the season. God forbid we need the depth at QB, but obviously it is nice to have another guy who is ready.
Army's Starting QB Selected
Wednesday, August 21, 2013
Posted by Chris at 8/21/2013 11:20:00 PM
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One after another, thousands upon thousands of dollars, your credit card debt is mounting to the point that you don't see a foreseeable end in sight.
When that moment arrives and you realize you're swimming in a sea of credit card debt, the easy out is you refusing to take any responsibility for what's happening and instead place the onus on the credit card companies themselves and using their high interest rates and unrealistic minimum payments as reasons why you're struggling.
Your credit woes and that poor credit score to boot didn't come from any of the major credit card companies but rather sits squarely on your shoulders for opening up too many lines of credit, charging that new fall wardrobe or maxing out more than one card for that vacation you knew you couldn't afford at the moment.
Bad credit isn't something that is given; it's earned. If you're having trouble with debt and don't have an admirable credit score, chances are something played into that predicament that you had at least some control over, not withstanding a major medical issue or something else that put you in this precarious spot.
You have to truly analyze how you've been spending money and if you're organizational skills are up to par before you start handing out blame at a moment's notice.
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New Kit Just Added
- Flat Bench Press
- Lying Leg Curl
- Hyper Extension (Free Standing Back Extension)
- 10 additional spin bikes taking us up to 30 bikes
- 20 New Kettlebells Ranging from 4 - 24kg
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So many people get trapped in contracts they no longer need when their circumstances change. At PureGym, we don't believe in contracts, just a monthly membership you are free to cancel whenever you like without paying a penalty. With PureGym, you're always in control!
Don't be concerned that because we're a cheap gym you will be sold short and find yourself queuing to use the equipment. Far from it! We have more than 220 top-quality pieces of kit in all of our 150+ gyms set in spacious and air-conditioned surroundings. Get your fix of state-of-the-art cross trainers, indoor bikes, treadmills, steppers and rowers, but if you'd like to experience something different try out Pure Fit, a multi-functional area centred on the rig and several pieces of great apparatus which will give you a great all-round work-out.
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I now understand why the Stockbridge Country Inn garners such good reviews on TripAdvisor. The inn is set on a hill off Rt. 183 just down the road from the Rockwell Museum and the Berkshire Botanical Garden. It's also within 10 minutes from Tanglewood and the quaint towns of Stockbridge and Lenox. So it has location in its favor. The rooms are spacious, spotless, and decorated in old New England style. The breakfast consists of eggs cooked to order and delicious, fresh pastries. So it has style and cuisine in its favor. But what really sets it apart is the staff, which is uniformly friendly and helpful, especially the innkeeper, Diane. Breakfast is served from 8:30 to 10 am, which seems civilized, but is a tad late for me since I have yet to shake off my working wakeup time. Our first morning there, I was wandering around at 7 am or so and bumped into Diane, who apparently had just left her bed. When I told her I was looking for coffee, she took me into the kitchen and brewed a cup on the spot. That's a small thing, but it's typical of this inn's welcoming and helpful attitude.
- Official Description (provided by the hotel):
- Closest Inn to The Norman Rockwell Museum and Chesterwood Museum, 5 minutes to Tanglewood, Central of all major Berkshire attractions, set up high on 4 private and professionally landscaped acres, in-ground swimming pool, bicycle and ski storage, full-service country breakfast, private bath en-suite, fine antiques, comfort at your service! ... more less
- Reservation Options:
- TripAdvisor is proud to partner with Booking.com, Travelocity, Hotels.com, Orbitz, Priceline, Hotwire, Expedia, Cheap Tickets and Cancelon so you can book your Stockbridge Country Inn reservations with confidence. We help millions of travelers each month to find the perfect hotel for both vacation and business trips, always with the best discounts and special offers.


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8 Comments
hannahannah Artist
i like this! :)
oooh… i want this design!!!
hope you win on this !!
stashvamps Artist
this is my favorite of yours!! awesome!
bobGnarley Artist
super , you definitely should have received some more votes
cool design +1
o_lucky_man Artist from Denmark
as soon as it possible i buy this… i love this
I love the talking heads! this is wonderful.


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Today in Photographs: August 4, 1942
Actress Loretta Young visits Victory House in Pershing Square, as part of a War Bond drive.
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text: PhotosEdit 1 of 10Add photoVideosEdit 01:34Sean Teale & Jonathon Kelt ALS Ice Bucket Challenge!02:26Jonathan Keltz dishes on The CWs 'Reign,' listening to Beyoncé and his surprising hidden talent08:47MuchMusic - Jonathan Keltz on New.Music.Live.11:31Jonathan Keltz Interview for BridgetMarieMagazine.com01:06:20Reign After Show w Jonathan Keltz Season 1 Episode 20 "Higher Ground" AfterBuzz TV03:27Reign Rapid Fire Jonathan KeltzAdd a photo to this gallery Retrieved from "http://reign-cw.wikia.com/wiki/Jonathan_Keltz/Gallery?oldid=54261" Ad blocker interference detected! Wikia is a free-to-use site that makes money from advertising. We have a modified experience for viewers using ad blockers Wikia is not accessible if you've made further modifications. Remove the custom ad blocker rule(s) and the page will load as expected. Categories: Gallery Cast Gallery Add category Cancel Save


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By Anthony Breznican, USA TODAY
PARK CITY, UTAH A Ginsburg poem with animation. Rich men gone poor. An improvised love story. A man buried alive in a wooden coffin. Here's Sundance:
LIVE FROM SUNDANCE: Follow all the action in our blog
That's the theme of the Sundance Film Festival this year, with several animated intros featuring the word playing before every movie. In the gift shop, you can even find a baby onesie emblazoned with the motto.
It's a chance for actors to take a risk: Kristen Stewart ditching her mournful good-girl image from the Twilight films to play a foul-mouthed, angry prostitute in Welcome to the Rileys, or Joseph Gordon-Levitt losing the clean-cut (500) Days of Summer look to play a long-haired, homemade-tattoo-wearing pyromaniac rabblerouser in Hesher.
The opening festival drama Howl spends a full third of its running time simply reading Allen Ginsberg's poem, accompanied by colorful surreal animation.
Here are some other risky moves made at the festival this weekend:
Lifestyles of the (formerly) rich
The Company Men strikes at something everyone fears in a troubled economy: the loss of a job, an identity and everything someone has worked for.
But can an audience empathize with high-priced, white-collar workers who find themselves driving their Porsches to the unemployment line?
Tommy Lee Jones is the conscience-rattled founding executive of an international transportation company; Chris Cooper plays a former welder who worked his way up to middle management; and Ben Affleck stars as a hotshot sales agent whose massive home, country-club membership and self-destructive pride are all assets he is forced to surrender.
"These characters are people who have achieved the American dream," Affleck says.
"Here's a guy who grew up pretty lower-working-class but worked hard, played by the rules, went to the good schools and made his way all the way up to where he got the job, got the car and made it," he says of his character. "And then he gets busted all the way back down. It's about the betrayal of what we're told about the American dream."
Rosemarie DeWitt (Rachel Getting Married), who plays his wife, says The Company Men is a cautionary tale about mistaking wealth for happiness.
"It's different when you see someone who has it, and loses it, and discovers something more meaningful," she says. "And yet we're all caught up in 'I've gotta have it, I've gotta get it, and that's when I'll truly be happy.' "
A reel-life 'Valentine'
Blue Valentine is fiction, but it was created like a documentary. The actors lived their parts as the camera crew followed their every move.
The result is a tragic love story about a couple — played by Ryan Gosling and Michelle Williams— trying to reclaim their passion, intercut with memories from the dawn of their romance.
Director Derek Cianfrance "wanted to make it as voyeuristic as he could," Gosling says. "A lot of things we did for real. For instance, we really got married by a justice of the peace. We lived in this house together, and we'd fall asleep, and in the morning the whole crew would sneak in and shoot us waking up."
Much of the movie, which premiered Sunday, was improvised.
"We wrote our own vows when we got married, we were there with other people getting married ..." Gosling says. "I guess the only reason it's not legit is we used our character names."
Boxing Ryan Reynolds
Buried is a one-man show that takes place entirely in a wooden coffin, underground.
Ryan Reynolds plays an American truck driver in Iraq, taken hostage and buried alive. A cellphone is his only connection to the outside world. The claustrophobic thriller, directed by Rodrigo Cortes and written by Chris Sparling, was once on a famous Hollywood list of brilliant, but impossible-to-make, screenplays. But after Saturday's midnight debut, Buried quickly became known as a must-see.
"I hope you enjoy watching this film as much as I hated making it," Reynolds joked while introducing the premiere. "Physically, it was tough. I liken it to wearing a slightly roomy sweater made of wood, blood and sand."
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SWITZERLAND: Fiat break-even slips a year - report
Fiat Auto does not expect to break even on an operational level before 2004, chief executive Giancarlo Boschetti said on Tuesday, according to Reuters.
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