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French Kicks
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Looking for thrills, frills n high leg kicks? The French Kicks cancan troupe stimulate excitement and Gay abandon at every event they attend. Made up of the crème of the cabaret crop, the French Kicks dancers give a nod, wink and an Ooo lala to whatever tickles your fancy!
Take three renowned Burlesque performers, add Three established
dancers, mix in high-jinks, high-kicks (12 legs' worth), a lavish helping of frills n' thrills, place into the cultural melting pot of London's cabaret scene and bring to the boil. Place in sumptuous Can Can frocks, garnish with authenticity, technique, creativity and flair.
The French Kicks are possibly the finest Can Can troupe this side of the
Moulin Rouge……..Served hot.
The French Kicks perform regularly at The Café de Paris and have danced for companies including Tesco, Bloomberg and Loose Women.
Some of Joogleberry's Clients...


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- Free breakfast and free parking
Main amenities
- 16 guestrooms
- Restaurant and bar/lounge
- Outdoor pool
- Free train station pick-up
- Airport shuttle
- 24-hour front desk
- Air conditioning
- Garden
- Library
- Multilingual staff
- Barbecue grills
- Free breakfast and free parking
Feel at home
- Cribs/infant beds available
- Rollaway/extra beds available
- Refrigerator
- Television
- Garden
- Hair dryer
What's around
- Porto dell' Etna (1.1 mi / 1.7 km)
- Basilica di San Pietro (1.2 mi / 1.9 km)
- Marina di Cottone Beach (5.6 mi / 9 km)
- San Marco Beach (6.7 mi / 10.8 km)
- Adventure Park Etna (8.5 mi / 13.7 km)
Hotel Info: 020 3027 9803from £80
- Standard Quadruple Room
- Standard Triple Room
- Standard Double or Twin Room
- Standard Single Room
- Superior Quadruple Room
- Superior Triple Room
- Superior Double or Twin Room
- Superior Single Room
More great choices
At a glance
Key facts
Hotel size
- This hotel has 16 rooms
- Check-in time starts at noon
- Check-out time is 10 AM
Required at check in
- Credit card or cash deposit required
- Government-issued photo ID required
Travelling with others
Extra people
- Rollaway beds available, charges may apply*
- WiFi in rooms *
- Free train station pickup
- Free self parking
In the hotel
- Free breakfast
- Restaurant
- Bar/lounge
- Room service (during limited hours)
- Barbecue grills
- Outdoor pool
- Mountain biking nearby
- 24-hour front desk
- Multilingual staff
- Garden
- Library
In the room
- In-room climate control (air conditioning)
- Air conditioning
- Balcony
- Hair dryer
- Cable/satellite TV channels
- Desk
- WiFi (surcharge)
- Refrigerator
Also popular with travellers from the UK
Galea's small print
Also known as
- Galea Country House Riposto
- Galea Riposto
- Galea Riposto
- Galea Country House Riposto
- Agriturismo Galea Riposto, Sicily, Italy
All guests, including children, must be present at check-in and show their government-issued photo ID card or passport.
Cash transactions at this property cannot exceed EUR 2999.99 owing to national regulations. For further details, please contact the property using information on the booking confirmation.
Mandatory fees
You'll be asked to pay the following charges at check in or check out:
- A tax is imposed by the city: EUR 1.5 per person, per night, up to 10 nights.
Optional extras
WiFi is available in guestrooms for an extra charge
We have included all charges provided to us by this hotel. However, charges can vary, for example, based on length of stay or the room you book.
Is the description of this hotel not correct? Tell us

subset: commoncrawl


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An appointment at a massage therapist's office led to a business partnership and has brought a new exercise bootcamp to Ahwatukee Foothills.
Lee Gough, owner of Core Fitness Concepts, a personal training company, moved to the United States from the United Kingdom seven years ago, and saw an opportunity to practice his passion after a lifelong interest in health and fitness.
The bootcamps are a "results-based program" that encourage lifestyle changes and provide clients with meal plans and grocery shopping lists, Gough said.
"Abs are made in the kitchen, not just the gym," said Melissa Larimore, Gough's business partner, massage therapist and bootcamp director for the new Ahwatukee Foothills venture.
The newest camp is slated to begin March 15 and will offer classes three times a week at Mountain Park Church, 2408 E. Pecos Road. Each session lasts 45 minutes.
Although there is no affiliation with the church, Larimore is happy to hold the outdoor camps there because trainers and participants can use the structures like hills and outdoor benches. Some clients bring yoga mats.
"There's no more boring hours at the gym, and you don't need expensive equipment," Gough said.
The "challenging, motivating" workouts are designed to work every muscle in the body, and are open to all fitness levels, he said.
"The most powerful aspect is the social support you receive from the group. Other people are there with the same goals."
Some people use the camps as a way to nurse injuries, combat high blood-pressure, lose baby weight, or add flair to mundane workout routines, Gough said.
Starting at 5:30 a.m. is ideal for busy moms and professionals, he added.
Larimore joined other bootcamps because "like many moms, I wanted to lose weight and get in shape," she said.
She prefers Gough's Core Fitness camps because she can work out and be home before her kids wake up.
In addition to in-person sessions, the group sends workouts via e-mail for those traveling, and makes personal phone calls for encouragement and to answer questions.
A two-week free trial is available to all first-time clients. For those who continue with the camps, an initial three-month commitment is required to accurately gauge results. A money-back guarantee is offered.
Gough said he sees most participants lose between 10 and 12 pounds in their first month.
Camps cost $199 per month for the first three months. Many discounts are available for referrals, corporate participation, etc.
Gough worked as a personal trainer at a national fitness chain for five years before opening his own business for the opportunity to be more personable with clients, and train people his own way, he said.
He opened two camps in Arcadia, one in Phoenix, and offers in-home personal training services to clients.
For more information, contact Larimore at firstname.lastname@example.com.
Kathleen Gormley is interning this semester for the Ahwatukee Foothills News. She is a sophomore at Arizona State University.


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I have been texting a guy from on-line for several weeks. We have been planning to meet up when I move to his area. A few days prior to me driving the 16hours for the move I tell him I'm driving down on Friday, Saturday I'm spending with my family/recovering and Sunday is all for him. He responds "Wow, you really know how to make a guy feel special." So I drive down Friday and reach my destination it is midnight and he tells me "You should drive the extra 45mns to see me." I'm like no, I'm exhausted and sore. So he says "tomorrow is the day" I say no, I'm spending time with family and recovering from drive." So later that night he again presures me to see him, I'm starting to get annoyed and then he texts "Sorry, I'm just excited to see you, we have been texting over a month." Then a few mins later... "I'm good though, we don't need to see eachother tomorrow." Then follows up with "Wish you were here." So I say nothing, and then Sunday he texts me "Good morning! I'm so sun burnt from yesterday." I havn't responded as I am confused as to what happened. Was he being selfish/disrespectful or am I making too big a deal here?
Most Helpful Guy
I think he sounds like a fucking stupid, unreasonable moron, he's exhibiting signs of being a little bitch already... usually people wait till they feel like they've got you before you see their true, needy little colors. Do what you want, women are typically quite forgiving and give guys chances, but I think carrying on with him will bite you in the ass.22|00|0
Thank you, I appreciate your opinion, and agree. It was such a turn off I didn't even want to see him anymore :/ Like, I was on the road since 8am until midnight and you think it's ok to pressure me to see you for the first time? Wtf lol
- Show AllShow Less
Big up, thanks for mho!
Welcome sir ;)
Most Helpful Girl
No he was definitely being selfish and inconsiderate. While I understand he was excited, that shouldn't mean he's allowed to totally disregard your feelings and well being for the sake of getting what he wants faster. Relationships require consideration and patience and you'd be doing right to tell him that.11|00|0
Personally, I wouldn't see this guy ever. He sounds like a prick.
yeah, after his inconsiderate display... I am soo turned off I don't want to


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The Great Transformation: how China changed in the long 1970s [Audio]
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Who Owns Fairtrade? A debate on who benefits, influences and controls Fairtrade [Audio]
Speaker(s): Pauline Tiffen, Rajah Banerjee; Kate Sebag; Katie Stafford; Dyborn Chinonga | The idea of fair trade has become increasingly popular amongst consumers and some producers. But who does fair-trade really benefit? The producers? The consumers? The Farmers? These are some of the issues that the panel will debate.
Many Voices: understanding the debate about preventing violent extremism [Audio]
Speaker(s): Hazel Blears MP | The tragic events of 7/7 illustrated the threat to our society posed by violent extremism. Preventing it is one of the defining challenges of our age. Hazel Blears will explore the tough choices government has to make - how to empower new voices to join the debate, how to support people standing up for shared values and how to equip communities with the skills, confidence, and resilience they need to be part of the solution. In June 2007, Hazel Blears became the Sec
LSE Literary Weekend - ReaLITy: creative responses to social realities [Audio]
Speaker(s): Morris Gleitzman, Elizabeth Laird; Anthony McGowan; Patrick Ness; Meg Rosoff | The culmination of a creative-writing competition for London state schools, this panel discussion looks at how authors find inspiration in contemporary social issues- from gang culture and knife crime, to the more timeless problems of being a teenager. The panel of popular and award-winning teen authors have dealt with topics as wide ranging as Ethiopian street children and Nazi Germany, with a mixture of
LSE Literary Weekend - The Founders' Tradition: literature as social commentary [Audio]
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China in International Society: can 'peaceful rise' succeed? [Audio]
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Thinking Like a Social Scientist: a lecture by Professor Gilat Levy [Audio]
Speaker(s): Professor Gilat Levy | In this lunchtime series lectures, a selection of LSE's academics from across the spectrum of the social sciences explain the latest thinking on how social scientists work to address the critical problems of the day. They survey the leading ideas and contributions made by their discipline, explain the types of problems that are addressed and the tools that are used, and explore the kinds of solutions proposed.
Majority Judgement: a completely new voting system. Part Three - Majority Judgement Compared with Ot
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Changing Values for a Just and Sustainable World [Audio]
Speaker(s): Professor Peter Singer | We live in a world of great affluence as well as extreme poverty, and in which the rich nations play a disproportionate role in changing the planet's climate, from which the poor will suffer most. What values would best guide us to a more just and sustainable world? Can we realistically expect them to be put into practice?
Consolidating Kosovo's European Future: tracing next steps [Audio]
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All That Life Can Afford [Audio]
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Housing Markets and the Global Financial Crisis [Audio]
Speaker(s): Dr André Broome, Professor Herman Schwartz, Professor Leonard Seabrooke, Professor Mat Watson | Residential property is the single largest asset in people's everyday lives and its associated mortgage debt constitutes one of the biggest financial assets in most economies. Yet political economy largely ignores both. We know that the kind of housing people occupy and their level of debt affects their preferences for the level of public spending, taxation, and inflation. Housing is inti
An Alternative to Statecraft: should diplomacy adapt to a new world environment? [Audio]
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Building windmills not walls - Hungary's approach in the economic storm [Audio]
Speaker(s): Gordon Bajnai | Gordon Bajnai has been the Prime Minister of Hungary since 14 April 2009. Prior to this between 2008-2009 he was a Minister in the Ministry for National Development and Economy. Between 2007-2008 he was a Minister for the Ministry of Local Government and Regional Development. Prior to this he was CEO of Wallis Rt., an investment company from 2000-2005.
Cities and the Environment [Audio]
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The International economy, and the process of the citizen's revolution in Ecuador [Audio]
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Thinking about Evidence and Risk [Audio]
Speaker(s): Professor John Worrall | In this lunchtime series of lectures, a selection of LSE's academics from across the spectrum of the social sciences explain the latest thinking on how social scientists work to address the critical problems of the day. They survey the leading ideas and contributions made by their discipline, explain the types of problems that are addressed and the tools that are used, and explore the kinds of solutions proposed.
Social Theories of Risk and Economic Life [Audio]
Speaker(s): Dr Nigel Dodd | In this lunchtime series of lectures, a selection of LSE's academics from across the spectrum of the social sciences explain the latest thinking on how social scientists work to address the critical problems of the day. They survey the leading ideas and contributions made by their discipline, explain the types of problems that are addressed and the tools that are used, and explore the kinds of solutions proposed.
Modernity and the Meaning of Life [Audio]
Speaker(s): Dr Simon Glendinning, Dr Edward Skidelsky | This dialogue will examine the resources left to us to find meaning in our modern day lives. Simon Glendinning is a reader in European philosophy at the European Institute, LSE, and director of the Forum for European Philosophy. Edward Skidelsky is a lecturer in the Department of Sociology at the University of Exeter.
Child Under-nourishment as a Social Predicament [Audio]
Speaker(s): Professor Amartya Sen | This lecture is in honour of Dr Indraprastha Gordhanbhai (I.G) Patel who was the ninth director of the London School of Economics from 1984 to 1990. Amartya Sen is Thomas W. Lamont University Professor, and Professor of Economics and Philosophy, at Harvard University and was until recently the Master of Trinity College, Cambridge. He has served as President of the Econometric Society, the Indian Economic Association, the American Economic Association and the I


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Running Time: 109 minutes
Released: 01/2008
Studio Name: Evasive Angles
Series: Orgy World Brown and Round
Director: T.T. Boy
Description: The original gangsta party sex flick is back - Number 12 is stacked with dime pieces. 2 big orgies, 2 full dicks of crazy wild, hot and horny freaks! The superstar of all butts, Skyy has graced this mega movie and she looks better than ever! There are so many beautiful big butts. Brand new girls like Shai, Tiffany, Kelly Dominique - too many to list - plus the sex is great and there's even girl-girl action!
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Franchising Opportunities with Cost Cutters
Every Cost Cutters hair salon franchise owner has been where you are right now—contemplating the idea of owning a business. You're considering the risk factors, the work involved, the financial investment and which type of business is best suited for you.
Salon franchise owners have the advantage of starting immediately with the benefits of name recognition, proven operating practices, shared buying power, marketing support, on-site training, business consulting and more.
For additional information on Regis Family of Brands franchise opportunities, visit www.regisfranchise.com.
This website and the salon franchise sales information on this site do not constitute an offer to sell a franchise. The offer of a franchise can only be made through the delivery of a franchise offering circular. Certain states require that we register the franchise offering circular in those states. The communications on this website are not directed by us to the residents of any of those states. Moreover, we will not offer or sell hair salon franchises in those states until we have registered the franchise (or obtained an applicable exemption from registration) and delivered the franchise offering circular to the prospective franchisee in compliance with applicable law.


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by Red Cell
Jeremy Barnes of Hawk and a Hacksaw and Neutral Milk Hotel fame has teamed up with the outstanding Cooper-Moore to form the Cooper-Moore/Barnes Duo. Barnes has also worked and recorded with Bright Eyes, Beirut, Broadcast. Cooper-Moore is a world-renowned jazz improviser, multi-instrumentalist, composer, storyteller, instrument-builder and educator. You can read all about Cooper-Moore's very interesting life as he tells it here. The Cooper-Moore/Barnes duo is a new project that the two have discussed for years. They will be recording an album in the Spring and playing shows in New Mexico (see below) and New York in June of 2010.
Friday, Feb 26th, UNM Arts Lab, Albuquerque – 7:30 pm
Saturday Feb 27th The Process Presents @ The Santa Fe Complex – 8:00 pm
Sunday, Feb 28th, El Rito Library – 3:00 pm
From the press release:
Multi-instrumentalist, composer, storyteller, instrument-builder and educator Cooper-Moore's approach to music has gone beyond simple categorization. His work emerged from the jazz avant-garde, but never lost sight of the traditions he deems so important. This adherence to tradition is reflected in his name, derived from the family names of his two grandmothers and adopted in 1985.
Born Gene Y. Ashton in rural Virginia on August 31, 1946, Cooper-Moore recognized the power of community very early in his life. He relates that on a Saturday in September 1954, his mother, the minister and Sunday School teacher of the family's church, and his first-grade teacher sat down at the kitchen table where serious business was discussed. It was decided then that he would play piano, giving his first recital in Sunday school six months later.
"I never had to search for who I was or was going to be," he said. "The elders chose for me—a musician; it has always been special."
He played piano in church throughout his youth, but developed an increasing fascination with jazz. Horace Silver and Ahmad Jamal were early formative influences on his piano playing. At age thirteen, he first heard the innovative orchestrations of Charles Mingus, and began to dream of moving to New York.
Through his teenage years, Cooper-Moore practiced piano, read voraciously from jazz magazines sent to him by relatives, and listened avidly to many musical styles and genres. He also developed interests in shortwave radio, electronics and astronomy, all of which were supported by his parents, who encouraged him to maintain his individuality. He studied physics and advanced math at Norfolk State College under a National Science Grant in the summer of 1962.
He began to focus his energies on jazz in the mid-sixties, when the experimental playing of John Coltrane, Cecil Taylor and Ornette Coleman began to coalesce into a movement that some would call the "New Thing," or even a "Jazz Revolution."
He attended Washington, DC's Catholic University from 1964 to 1966, and Boston's Berkeley School of Music in 1967. However, he gravitated towards collaborations with other musicians who also identified with the "New Thing," and sought to surround himself with talented performers who were constantly playing and composing this music.
One key collaborator from this time was saxophonist David S. Ware. Along with drummer Mark Edwards, Cooper-Moore and Ware founded the group Apogee in 1970. The group played from 1970 to 1974, and opened for Sonny Rollins at New York's Village Vanguard in 1972. Their work is documented on one album recorded years after the fact, Birth of a Being (Hat Art, 1978),
Cooper-Moore moved from Boston to New York in June of 1973, but his stay in the city was short-lived, and he returned to Virginia in 1975. Over the next ten years, he built instruments and worked as a music therapist with the severely handicapped. He was eventually hired by the Wolf Trap foundation in Virginia, using music to teach in the Headstart program for young children.
His educational philosophy deals with compartmentalization and memory development through the use of music; Recognized internationally for his work in the classroom as well as in shelters for the homeless and for battered women, Cooper-Moore continues to teach and to instruct teachers to use his methods.
In 1985, Cooper-Moore moved back to New York with his second wife and youngest son. In the early 1990s, he joined New York's Improvisers' Collective, a group of artists from many disciplines, and began the series of recordings for which he is best known.
These have included work with William Parker's large ensemble In Order to Survive (AUM Fidelity), Bill Cole's Untempered Ensemble (Boxholder) and various collaborations with multi-instrumentalist Assif Tsahar (Hopscotch.) He has performed with Butch Morris and fronted the trio Triptych Myth with bassist Tom Abbs and drummer Chad Taylor.
From 2007 to 2008, he led a group in which he played organ for the first time since the late 1960s. A 2006 trio with Tsahar and Chicago drummer Chad Taylor, Digital Primitives, found Cooper-Moore reviving his interest in electronics by using them as a sonic backdrop to the group's jazz-rock aesthetic.
Beyond performing and teaching, Cooper-Moore told stories in Brooklyn's Prospect Park on Sundays for ten years, spinning folktales under the park's "storytelling tree" for enthusiastic crowds.
A lover of theater, dance and of the human voice, he has been involved in multimedia productions since 1984. In 1998, he collaborated with Dance Theater Workshop in "A Mindset," comparing the U.S. Criminal Justice and Welfare systems.
Former U.S. poet Laureate Rita Dove's "The Darker Face of the Earth" (2000), for which he wrote the music, is a modern adaptation of the Oedipus story set in the enslaved South. Poet and dancer Marlies Yearby was choreographer for the project, she and Cooper-Moore performed together at New York's 2007 Vision Festival.
Cooper-Moore's interest in theater informs his entire oeuvre: his music is as theatrical as his stories are musical. His pianism can invoke moment-to-moment shades of Cecil Taylor's multilinear constructs or Jaki Byard's historically informed paraphrases. It exists, as one of his album titles proclaims, Deep in the Neighborhood of History and Influence.
Whether playing piano or any one of his homemade instruments, his music exudes a striking directness and simplicity that evokes everything from rhythm and blues to the simplest vocal monody. These points of reference lend his music multileveled appeal while always allowing for a fresh approach to composition and performance. They harken back to the infinitely complex yet starkly simple myths from which human communities draw for continued survival; for Cooper-Moore, this is as it should be. "We often forget the simplest human emotions, and it's part of my job as a musician, as a performer, to remind people."
A native of Albuquerque, New Mexico, Jeremy Barnes began playing music professionally at the age of 19, with a then unknown psych/folk band called Neutral Milk Hotel. After touring extensively in the U.S and Europe, the band split up and Barnes moved to Chicago, where he worked at the Hothouse (Center for Creative Music), where he met many of the improvising music scene's greats- Roscoe Mitchell, William Parker, Han Bennink and Cooper Moore, among others. He moved to France in 2000, where he formed the project A Hawk and A Hacksaw. After a few albums and tours of Europe and The U.S., the band was awarded a grant from the Arts Council of England, which funded a high profile tour of the UK as well as an ongoing collaboration with 4 Hungarian folk musicians. In 2007 they were also awarded best live music performance at the Brighton Fringe Festival in Brighton, England. Barnes and Heather Trost, violinist in A Hawk and a Hacksaw, moved to Budapest for two years as a result of the Arts Council grant and tour. . In 2008 they returned home to New Mexico, and have toured more in the U.S. and Europe as well as Australia, Israel, and Turkey. They sold out the Outpost performance space in the fall of 2009.


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Graduate Opportunity - Asset Engineer
- Recruiter
- Location
- Walsall
- Salary
- £25000
- Posted
- 06 Oct 2016
- Closes
- 19 Oct 2016
- Sector
- Engineering
- Contract Type
- Permanent
Graduate Opportunity - Asset Engineer Our client delivers clean and reliable water supplies to around 1.5 million customers within the South Staffs and Cambridge regions. This new role has been created to support the growing demand for the provision of water and to ensure they maintain an efficient and effective service for their customers. Position: Graduate Opportunity - Asset Engineer Location: Walsall, West Midlands Salary: £25,000 per annum Closing Date: Friday 17th October 2016 About the role: They have a fantastic graduate opportunity for the successful candidate to support the continued development and delivery of their risk based Asset Management strategy. The primary focus of the role will initially be to translate risk mitigation and identified investment needs into detailed scopes for costing and scheme appraisal. The key responsibilities for the role will include the following: Strategic Planning - Undertake zonal risk assessments (using hydraulic models), supporting the team in maintaining the models, the delivery of the investment programme and development of maintenance strategies. Asset Optimisation - Devising asset optimisation strategies, minimising whole life costing of the asset base, undertake asset health checks and identify any contributory factors to infrastructure deterioration and failure. New Technology & Innovation - Lead innovation and assessment of new technology with the primary aim of ensuring that South Staffs remain at the forefront in terms of the management of its assets. About you: To be successful you will be educated to at least HNC or degree level in an engineering discipline, have an open, analytical and innovative mind as well as a flexible approach to work. You will be IT literate including MS Excel. Some knowledge and / or experience in using GIS, and of hydraulic clean water modelling software would be an advantage. In addition you must also possess a full valid driving licence as the role includes some field based work. The majority of the work will be based in their Walsall region with occasional travel to their Cambridge office as and when required. Previous proven asset management, along with capital scheme scoping / design experience would also be an advantage. You may have experience of the following: Engineering Graduate, Graduate Scheme, Asset Management, GIS, Modelling Software, Capital Scheme Scoping, Design, Graduate Training Scheme, Engineering Trainee, etc. This vacancy is being advertised by Easy Web Recruitment, the UK's leading Online Recruitment Agency. The services advertised by Easy Web Recruitment are those of an employment agency. No terminology in this advert is intended to discriminate on the grounds of gender, race, disability, age, sexual orientation, religion, or belief, and we confirm that we will gladly accept all applications. This job was originally posted as www.totaljobs.com/job/66806631


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Whatever the merits of adding another Test venue to an already extensive list, the last thing Hampshire County Cricket Club would have wanted to hear on the opening day of their First Test was barracking from the supporters. Yet this is exactly what happened shortly before the final session began yesterday.
After most of the day had been lost to rain, a spell of bright weather allowed umpires Aleem Dar and Rod Tucker to inspect at 5.30pm.
Conditions appeared playable shortly afterwards and the England team, keen to add to the three Sri Lanka wickets they had already taken, moved on to the outfield soon afterwards in anticipation of a quick resumption.
The re-start had been scheduled for 6pm, though, so the teams had to adhere to that time. Never mind that play could have begun again at least 10 minutes before then.
The sight of the England players unable to play elicited shouts of derision and a slow hand-clap from some of the crowd and it is hard to find fault with their opinion.
Yes, the players' safety and the suitability of the conditions must be uppermost in the officials' minds but it must also be remembered that cricket is a form of entertainment.
Some supporters would have paid up to £70 for a day at the Test and, while nothing can be done to control the weather, a little lateral thinking would come in handy when play is possible. After a final session lasting an hour and 20 minutes, the teams left the field with Sri Lanka on 81 for four but they could probably have continued playing for at least another half an hour as there was enough light to carry on.
The situation was exacerbated today as the rain fell again delaying the start and threatening to wipe out the entire day's play.
There is enough concern about the future of Test matches for the International Cricket Council to be pondering the introduction of day/night Tests, yet perhaps nothing quite so drastic is required. Greater consideration for the paying public would surely improve the situation.
It was not the first time in the series that spectators have felt short-changed. At Lord's, with the floodlights on, the umpires took the players off for bad light on the fourth afternoon - even though it was not discernibly darker than when they had ordered them to play on moments before. Sure enough, the teams were back on after a brief delay - and most in the ground were utterly baffled.
One of the more heartening moments of the opening day was the reception given to Chris Tremlett, playing a first-class match at the Rose Bowl for the first time since he left Hampshire for Surrey last summer after a decade competing for his home county.
Tremlett took a little time to find his stride but, in the final session, he bowled with real menace, removing Mahela Jayawardene, with a fierce delivery that lifted, took the edge and flew through to Matt Prior. When he has his preferred pace attack available, Strauss still gives the new ball to Stuart Broad instead of Tremlett, yet he might have to rethink this plan when India visit later in the summer.
The most effective spell of Broad's international career came in the final Test of the 2009 Ashes series, when he took five wickets in Australia's first innings as England's fourth bowler. And with the extra bounce and carry Tremlett generates, he seems the perfect foil for the swing of Jimmy Anderson - as the pair demonstrated in the final three Ashes Tests when Tremlett replaced the injured Broad.
"I enjoy bowling with Jimmy and I seem to bowl well with him in partnerships - and we did that pretty well on the first day here," said Tremlett, who claimed his first wicket yesterday by trapping Tharanga Paranavitana lbw.
"Broady's length and mine are slightly different, so to have Jimmy's variety - pitching the ball up and swinging it both ways - is good for the team. Because of my height, I feel a newer ball is going to help my attributes."
- More about:
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SYRACUSE, N.Y. (AP) Eric Ellestad (FSY) kicked a 35-yard field goal in overtime to give Minnesota a 20-17 victory over Syracuse on Saturday, spoiling the debut of Orange quarterback Greg Paulus in the opener for both teams.
GAME REPORT: Minn. 23, Syracuse 20 (OT)
Paulus was 19-for-31 for 167 yards and one touchdown, but the former Duke point guard threw his only interception in the extra period to give the Gophers the big break they needed.
Adam Weber (FSY) was 19-for-42 for 248 yards and Eric Decker (FSY) had nine catches for 183 yards to lead Minnesota.
Paulus had not played football since he was honored as 2004 national player of the year at Christian Brothers Academy in suburban Syracuse. New coach Doug Marrone, who played for the Orange in the mid-1980s, made Paulus the starter less than two weeks into the preseason.
Paulus showed great poise for somebody who had never played the position in college, and his offensive line provided good protection — Paulus was sacked just twice, one of which ended in a roughing the passer penalty against the Gophers.
Paulus appeared calm and collected for most the game, but his ill-advised pass on a scramble on the first possession of overtime sent the Orange to defeat.
Paulus, who received an NCAA waiver to play football at Syracuse with his one remaining year of athletic eligibility, seemed at home after the Orange's first snap of the game sailed way over his head and led to a quick Minnesota touchdown. He looked off defenders and scrambled when he had to, displaying the flair that made him a record-setting high school quarterback five years ago.
With Syracuse trailing 14-3 late in the first quarter, Paulus electrified the near-capacity crowd of 48,617, which included former Syracuse star Donovan McNabb, with his first collegiate scoring pass.
Facing a second-and-6 from the Minnesota 29, Paulus fooled three defenders with a pump fake and hit a wide-open Mike Williams (FSY) near the goal line to move the Orange within 14-10. It marked the 10th straight game Williams has had a TD catch, a school record.
Not even penalties seemed to faze Paulus. Despite a false start and a hold whistled against the Orange late in the second quarter, he guided Syracuse 67 yards in eight plays, accounting for all but 10 yards with four completions in four attempts.
Paulus hit Alec Lemon for 10 yards, Williams for 18 yards on a first-and-20 play, Antwon Bailey (FSY) for 15 yards on a screen, and Williams again for 14 yards to set up Delone Carter's (FSY) 1-yard touchdown run.
That gave the Orange, who were 10-37 in the previous four years under Greg Robinson, a rare 20-14 halftime lead. Syracuse scored 20 or more points in a game only eight times under Robinson.
The game started badly for the Orange. Center Jim McKenzie's first snap sailed over Paulus' head and was recovered by Minnesota's Cedric McKinley at the Syracuse 16. Two plays later, Duane Bennett (FSY) scored untouched on a 16-yard run around the right side.
Ellestad forced overtime with a 26-yard field goal with 57 seconds left in regulation after a lob by Weber for Decker in the right corner of the end zone sailed high.
The last time Paulus, who grew up in the Syracuse suburbs, played in the Carrier Dome, he led Christian Brothers Academy to its first state title.
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NCDC Recruitment
National Cooperative Development Corporation has circulated a walk-in advertisement regarding NCDC Recruitment. Job seekers who want to get employed under this government owned corporation against Consultants Vacancies may apply for NCDC Recruitment 2017. Appliers are informed that they need to rush for the walk-in interview along with essentials on the date that is specified below.
Focal Points of this Page
Fascinated aspirants may apply for these advertised vacancies by attending the Interview along with original particulars in support of academics qualification on specified dates as shown below. So, candidates are requested to go through the whole page to acquire latest info related to National Cooperative Development Corporation Recruitment that is provided by the team of recruitmentresult.com.
NCDC Recruitment
|Name of Corporation
|National Cooperative Development Corporation
|Total vacancies
|Date of Walk-in- Interview
|15th December 2016
NCDC Recruitment: Official Notification
Qualification Required for NCDC Jobs:
|Post Name
|No. of posts
|Essential Qualification
|Consultant (Epidemiologist)
|MBBS recognized by Medical Council of India (MCI) with MD (PSM/Community Medicine) / MD (CHA) / MD (Tropical Medicine)
|MBBS with MD/DNB in Medical Microbiology/Lab. Medicine; OR b) MBBS with Post Graduate Diploma such as D. Bact. / D. Virology
|Veterinary Consultant
|A Post graduate Veterinary degree
More Job Options:
Age Limitation and Remuneration Details:
|Post Name
|Age Limitations
|Consultant (Epidemiologist)
|62 years
|Rs. 60,000/-
|60 years
|Medical – Rs. 56,448/-
Non-Medical– Rs. 52,920/-
|Veterinary Consultant
|65 years
|Rs. 56,448/
Selection Process for NCDC Vacancy:
Candidates will be selected on the basis of interview process as aspirants are required to face the Interview for final assortment in the institute.
You may check given articles for clearing interview round:
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- Applicants reaching the venue after the scheduled time shall not be entertained under any condition. And no TA / DA will be given for attending the interview.
Venue for Interview:
National Cooperative Development Corporation,
Get More: Jobs in Delhi
Walk-In Date:
- Interview will be held on: 15th December 2016
- Registration time: 9:30 to 10:30 A.M.
Note: You may check Official Notification given above on this page to get complete details about NCDC Recruitment 2017. Applicants may add this page as bookmark to get recent updates time to time.
Something That You Should Put An Eye On:
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Author | exchange4media Mumbai Bureau | Saturday, Jul 01,2006 7:57 AM
Sify Ltd has announced the launch of its second city-centric website, www.mumbailive.in. The portal had launched a city-centric website on Bangalore in March this year. Mumbailive.in will provide original Mumbai-centric video content created exclusively for an online audience. These videos will focus on city news and events, entertainment, celebrities, lifestyle, commerce and politics.
Anchored by Net Jockeys, the website will have sections like Gossip, Bol Bachchan, Hip Haunts, Late Night, Cat Walk and News, that will feature currents happenings in the city, including Bollywood, clubs, music, news, hot topics, through daily news bulletins on video.
Speaking at the launch, Surya Mantha, Senior V-P, Interactive Services, Sify Ltd, said, "We intend to introduce more such city centric websites with the sole objective of creating a community for people to share their views, discuss hot local topics and build their own personal space online."
The website will have 24/7 live video feeds from traffic web-cams stationed at key junctions of the city, including Andheri, Bandra, Kandivali and Worli to begin with and will move to other key locations in the city.
Besides this, there will be sections such as Corporate Scan, India News, World News and Technology News to cater to people interested in the corporate world.
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Mantha further said, "The idea is to allow Mumbai's citizens living elsewhere to stay in touch with what's happening in their home city. We believe that the people of Mumbai will accept it and truly make it come alive."


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Genetic module and miRNome trait analyses reflect the distinct biological features of endothelial progenitor cells from different anatomic locations
Human and rodent genomics
Endothelial progenitor cells (EPCs) play a fundamental role in post-natal vascular repair, yet EPCs from different anatomic locations possess unique biological properties. The underlying mechanisms are unclear.
EPCs from CB expressed abundant genes involved in cell cycle, hypoxia signalling and blood vessel development, correlating with the phenotypes that CB-EPCs proliferated more rapidly, migrated faster, and formed tubule structure more efficiently. smRNA-seq further deciphered miRNome patterns in EPCs isolated from CB or PB: 54 miRNAs were enriched in CB-EPCs, while another 50 in PB-EPCs. Specifically, CB-EPCs expressed more angiogenic miRNAs such as miR-31, while PB-EPCs possessed more tumor suppressive miRNAs including miR-10a. Knocking down miR-31 levels in CB-EPCs suppressed cell migration and microtubule formation, while overexpressing miR-31 in PB-EPCs helped to recapitulate some of CB-EPC functions.
Our results show the foundation for a more detailed understanding of EPCs from different anatomic sources. Stimulating the expression of angiogenic microRNAs or genes in EPCs of low activity (such as those from patients with cardiovascular diseases) might allow the development of novel therapeutic strategies.
The progressive impairment of endothelial function and integrity starts a cascade of events, leading to microcirculation damage, atherosclerosis and common cardiovascular disease (CVD), such as coronary heart disease (CHD), myocardial infarction (MI), heart failure, stroke and peripheral arterial disease (PAD)
Clinically, circulating EPCs can be obtained from adult peripheral blood and umbilical cord blood. The number of EPCs in adult blood is known to be significantly lower than in cord blood
The above findings suggest that CB-EPCs have enhanced vasculogenic ability compared with adult PB-EPCs. However, the underlying mechanisms are unclear. EPCs from human umbilical cord and adult peripheral blood activate different mechanisms upon high-dose x-ray radiation treatment: CB-EPCs undergo p53 stabilization, Bax-dependent apoptosis and p21-dependent G1 and G2/M cell cycle checkpoints, while PB-EPCs undergo only radiation-induced senescence
In this study we explored protein-coding mRNAs and miRNAs involved in EPC activities. We found that CB-EPCs migrate faster and form tubule structures
Isolation and cultivation of EPCs
All patients gave informed consent, and the study was approved by the research ethics committee of the Hsinchu Mackay Memorial Hospital, Taiwan (ref number: 11MMHIS040). Protocols of this study were consistent with ethical guidelines provided in the 1975 Helsinki Declaration (
EPC tube formation, transwell cell migration and cell proliferation assays
A miR-31 cDNA construct was used in overexpression experiments
Cell migration ability was evaluated using Costar Transwell® Polycarbonate Permeable Supports (Corning, NY, USA) as previously described
mRNA microarray and bioinformatics analysis
Total RNA sample preparation, cRNA probe preparation, array hybridization and data analysis were done as described previously
Gene annotation was performed by our ArrayFusion web tool (
Small RNA sequencing (smRNA-Seq) and data analysis
Total RNA was collected and small RNA fractions were sequenced by Illumina Solexa Genome Analyzer IIx (GAIIx; Illumina, San Diego, CA USA) according to manufacturer's instruction. For data analysis, quality Fastq sequences, which were without poly-A, ambiguous nucleotides or a 5' adapter, yet flanking 6-18 nt of 3' adapter sequence, had the adapter sequences trimmed and the identical sequences were then collapse to unique sequences. The resulting unique sequences that did not align to mRNA database (UCSC genome browsers) but were aligned to known microRNA sequences (miRBase R18;
RNA extraction and real-time quantitative polymerase chain reaction (qPCR)
RNA extraction and reverse transcription were performed as previously described
Additional file 1 Figure S1
Primers used in RT-qPCR validation.
Click here for file
Isolation and characterization of human EPCs from cord blood and adult peripheral blood
EPCs were obtained from cord blood or peripheral blood of healthy subjects as described
Figure 1
Different angiogenic abilities between EPCs isolated from different anatomic locations.
Different angiogenic abilities between EPCs isolated from different anatomic locations. ( A) EPCs from cord blood (CB-EPCs) migrate faster than those from adult peripheral blood (PB-EPCs). EPCs from different sources were subjected to Transwell cell migration assays, and migrated cells were stained (representative pictures are shown) and counted (left panel, n = 3). *:P < 0.05 ( B) CB-EPCs form better microvasculature structures
Gene expression signatures and functional modules of different EPCs
To provide the underlying mechanisms for observed phenotypes, we explored the transcriptome patterns of different EPCs. Protein-coding mRNAs were deciphered first by Affymetrix whole-genome microarrays. A total of 753 probe sets (positive false discovery rate (pFDR) q < 0.005) were found unique to CB-EPC, while another 431 to PB-EPC (Figure
Additional file 2 Figure S2
Gene expression signatures and functional modules of different EPCs.
Click here for file
Figure 2
Distinct gene expression patterns of different EPCs
Distinct gene expression patterns of different EPCs. ( A) A heat map showing genes more abundant in CB-EPCs. Columns represent EPC samples from different donors, while rows represent probe sets. Genes in red: increased expression; in blue: decreased. ( B) A principle component analysis (PCA) plot using genes differentially expressed between different EPCs. Each spot represents a single array sample. ( C) The unique biological functions of CB-EPCs. CB-EPC-enriched genes were subjected to a Gene Ontology (GO) database search. These categories were selected from the "Biological Process" organizing principle in the GO database (
The above gene list gave us a primary insight into the unique composition of differential EPCs but reflected little on EPC functions. To understand more how gene expression profiles might correlate with EPC biology and to provide quantitative evidence, signature probe sets were subjected to Gene Ontology (GO) database search for finding statistically over-represented functional groups within these genes. Given that the whole human transcriptome was represented by the microarray analysis, this analysis was not biased toward the coverage of the microarray. The GO categories of the biological processes being statistically overrepresented (
We also subjected CB-EPC genes into KEGG and Ingenuity Pathway Analysis (IPA) database search for disclosing enriched pathways and functional modules. More information was revealed from Ingenuity database search. The "G2/M DNA damage checkpoint regulation" canonical pathway ranks the No. 1 most significant pathway found among CB-EPC genes (Figure
Additional file 3 Figure S3
Distribution of CB-EPC cell cycle genes according to the KEGG database. CB-EPC genes are labeled with red stars. The P value is also shown.
Click here for file
Unique miRNA expression profiles of different EPCs revealed by small RNA sequencing (smRNA-Seq)
Another level of gene expression regulation is through microRNAs. To provide a more comprehensive view of transcriptome profiles of EPCs from different sources, we determined miRNA profiles of different EPCs by sequencing the small RNA fractions of both EPCs. Illumina Solexa platform generated 9.7 million high-quality sequence reads for PB-EPCs, and another 11 million reads for CB-EPCs (Figure
Figure 3
Differentially expressed miRNAs between CB- and PB-EPCs discovered by smRNA-Seq.
Differentially expressed miRNAs between CB- and PB-EPCs discovered by smRNA-Seq. ( A) A table summarizes reads number (
Applying the genetic network analysis function in the IPA web tool, we searched for miRNA-mRNA pairs and networks in CB-EPCs. PB-EPC miRNAs, such as miR-10a/b, miR-26a, miR-103a, miR-107, miR-139-5p, miR-151b, miR-361-5p, miR-365 and miR-1290, were found to be master regulators of a subset of CB-EPC protein-coding mRNAs (Figure
Most of the differentially expressed miRNAs have not been linked to angiogenesis. MiR-410 is involved in regulating secretion
miR-31 as a novel EPC angiogenic miRNA
To identify more pro-angiogenic miRNAs involved in EPC activity, we examined which miRNA(s) may contribute in EPC angiogenesis. MiR-31 is a known pro-angiogenic and pro-lymphangiogenic miRNA which induce motility in both matured blood vessel and lymphatic endothelial cells
Additional file 4 Figure S4
Over-expressing miR-31 in PB-EPC (A) or knocking down endogenous miR-31 in CB-EPC (B) did not affect cell proliferation rate at a significant level in the first 24 hours of transfection.
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Figure 4
miR-31 is involved in EPC activities.
miR-31 is involved in EPC activities. ( A-C) Knocking down endogenous miR-31 in CB-EPCs. Anti-miR-31 antagomiR or the siGFP control (Ctrl) was introduced into CB-EPCs by electroporation, and 2 days later EPCs were subjected to tube formation (
Endothelial cells from the internal barrier of the vasculature, and play fundamental roles in vascular development and disease. The regulation of angiogenesis depends not only on the number of circulating EPC but also on their functions
An increasing number of studies shows that miRNAs, or angiomiRs, play a crucial role in regulating various aspects of cancer biology, including angiogenesis. Manipulating miRNAs in the settings of pathological vascularization therefore represents a new therapeutic approach
When PB-EPC genes were subjected into GO database search, we found these genes are enriched in both Wnt receptor signaling (8 genes including CREBBP, DVL3, NFAT5, PPARD, RAC1, TBL1X, TCF7L2, TP53; p= 0.019) and positive regulation of I-kappaB kinase/NF-kappaB cascade (6 genes including LITAF, MAP3K3, MAP3K7IP2, MUL1, TRIM13, PSMB7; p = 0.048). Genes involved in the induction of apoptosis are also more abundant in PB-EPCs (15 genes, p = 0.006). KEGG and IPA database search also revealed that genes involved in both Wnt signaling (p = 0.020) and MAPK (13 genes, including ACVR1B, ARRB1, DDIT3, DUSP3, DUSP16, ELK4, GADD45B, MAP3K3, MAP3K7IP1, MAP3K7IP2, MAPKAPK2, RAC1 and TP53; p = 012) pathways are more abundant in PB-EPCs (Additional file
Additional file 5 Figure S5:
Distribution of PB-EPC genes in the Wnt signaling pathway according to the KEGG database. PB-EPC genes are labeled with red stars.
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Additional file 6 Table S1
Distribution of PB-EPC genes in the MAPK signaling pathway according to the KEGG database. PB-EPC genes are labeled with red stars.
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Additional file 7 Table S2
Distribution of PB-EPC genes in the Wnt signaling pathway according to the IPA web tool. Involved PB-EPC genes are in green and indicated.
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In this study we applied RNA sequencing (RNA-seq) technology, instead of microRNA chips, for deciphering EPC miRNomes. This is due to the fact that microarray application in miRNome research has several limitations, including hybridization and cross-hybridization artifacts, dye-based detection issues and design constraints that preclude or seriously limit the detection of newly discovered miRNAs or previously unmapped, novel miRNAs
One of the CB-EPC-dominant microRNAs is miR-31, a pro-angiogenic miRNA that enhances endothelial cell migration
For miRNAs more abundant in PB-EPCs, miR-217 modulates endothelial cell senescence via silent information regulator 1 (sirT1)
In summary, our results reveal a series of differentially expressed miRNAs and protein-coding genes that have not previously been associated with EPC biology. This study therefore provides a road map for future mechanistic studies of EPC migration and microvasculature formation, which should eventually help to improve our understanding of angiogenesis, and will also benefit the development of new therapeutic approaches that target the inhibition of pathogenic angiogenesis in tumors, the stimulation of angiogenesis in patients with cardiovascular diseases, stroke or diabetes.
Competing interests
The authors declare no competing financial interests.
Authors' contributions
C-CC and H-HL carried out the study design, performed the statistical analysis and drafted the manuscript. H-H L and Y-CCcarried out the cell biology assays. T-SH and S-TC participated in sequence alignment. S-JC provided clinical samples. H-WW conceived of the study, and participated in its design and coordination and helped to draft the manuscript. All authors read and approved the final manuscript.
The authors acknowledge the technical services provided by Microarray & Gene Expression Analysis Core Facility of the National Yang-Ming University VGH Genome Research Center, which is supported by National Research Program for Genomic Medicine, National Science Council (NSC). This work is supported by NSC (NSC101-2320-B-010-059-MY3, NSC98-2320-B-010-020-MY3 and NSC100-2627-B-010-007), Tri-Service General Hospital (TSGH-C102-027), the Yen Tjing Lin Medical Foundation (CI-100-23), Mackay Memorial Hospital (MMH-HB-100-01), Taipei Veteran General Hospital (V101E2-008 and Cancer Excellence Center Plan DOH101-TD-C-111-007) and National Yang-Ming University (Ministry of Education, Aim for the Top University Plan). This work is also support in part by the UST-UCSD International Center for Excellence in Advanced Bioengineering sponsored by the Taiwan NSC I-RiCE Program under Grant Number: NSC100-2911-I-009-101.
Microcirculation and oxidative stress
Therapeutic potential of endothelial progenitor cells in cardiovascular diseases
Cardiovascular risk factors impair native collateral development and may impair efficacy of therapeutic interventions
Hypertension and microvascular remodelling
Aging and hypertension are independent risk factors for reduced number of circulating endothelial progenitor cells
Correlations between progression of coronary artery disease and circulating endothelial progenitor cells
Expression of VEGFR-2 and AC133 by circulating human CD34(+) cells identifies a population of functional endothelial precursors
Functional module analysis reveals differential osteogenic and stemness potentials in human mesenchymal stem cells from bone marrow and Wharton's jelly of umbilical cord
Unique biological properties and application potentials of CD34+ CD38- stem cells from various sources
Identification of a novel hierarchy of endothelial progenitor cells using human peripheral and umbilical cord blood
Differential in vivo potential of endothelial progenitor cells from human umbilical cord blood and adult peripheral blood to form functional long-lasting vessels
In vivo vasculogenic potential of human blood-derived endothelial progenitor cells
Differential mechanisms of x-ray-induced cell death in human endothelial progenitor cells isolated from cord blood and adults
AngiomiRs–key regulators of angiogenesis
Role of microRNAs in endothelial inflammation and senescence
Targeting microRNA expression to regulate angiogenesis
Identification of Fat4 as a candidate tumor suppressor gene in breast cancers
The manipulation of miRNA-gene regulatory networks by KSHV induces endothelial cell motility
MicroRNA-378 promotes cell survival, tumor growth, and angiogenesis by targeting SuFu and Fus-1 expression
miR-296 regulates growth factor receptor overexpression in angiogenic endothelial cells
MicroRNA-132-mediated loss of p120RasGAP activates the endothelium to facilitate pathological angiogenesis
Vascular endothelial function and circulating endothelial progenitor cells in patients with cardiac syndrome X
High glucose impairs early and late endothelial progenitor cells by modifying nitric oxide-related but not oxidative stress-mediated mechanisms
Kaposi sarcoma herpesvirus-induced cellular reprogramming contributes to the lymphatic endothelial gene expression in Kaposi sarcoma
Linear models and empirical bayes methods for assessing differential expression in microarray experiments
Statistical significance for genomewide studies
ArrayFusion: a web application for multi-dimensional analysis of CGH, SNP and microarray data
Mapping and quantifying mammalian transcriptomes by RNA-Seq
miRTar: an integrated system for identifying miRNA-target interactions in human
Andes virus regulation of cellular microRNAs contributes to hantavirus-induced endothelial cell permeability
Plasma microRNA profiling reveals loss of endothelial miR-126 and other microRNAs in type 2 diabetes
Deregulation of microRNA-503 contributes to diabetes mellitus-induced impairment of endothelial function and reparative angiogenesis after limb ischemia
Functional network reconstruction reveals somatic stemness genetic maps and dedifferentiation-like transcriptome reprogramming induced by GATA2
MicroRNA-24 regulates vascularity after myocardial infarction
MicroRNA-100 regulates neovascularization by suppression of mammalian target of rapamycin in endothelial and vascular smooth muscle cells
MicroRNA-29b suppresses tumor angiogenesis, invasion and metastasis by regulating MMP-2 expression
The M type K15 protein of Kaposi's sarcoma-associated herpesvirus regulates microRNA expression via its SH2-binding motif to induce cell migration and invasion
Endothelial progenitors in vascular repair and angiogenesis: how many are needed and what to do?
Outgrowth endothelial cells: sources, characteristics and potential applications in tissue engineering and regenerative medicine
Therapeutic stem and progenitor cell transplantation for organ vascularization and regeneration
Prospective randomised trial evaluating a paclitaxel-coated balloon in patients treated with endothelial progenitor cell capturing stents for de novo coronary artery disease
Anterior endomesoderm specification in Xenopus by Wnt/beta-catenin and TGF-beta signalling pathways
Wnt1 is a proangiogenic molecule, enhances human endothelial progenitor function, and increases blood flow to ischemic limbs in a HGF-dependent manner
RNA-Seq: a revolutionary tool for transcriptomics
miR-31 functions as a negative regulator of lymphatic vascular lineage-specific differentiation in vitro and vascular development in vivo
MicroRNA 217 modulates endothelial cell senescence via silent information regulator 1
MicroRNA-320 expression in myocardial microvascular endothelial cells and its relationship with insulin-like growth factor-1 in type 2 diabetic rats
MicroRNA miR-93 promotes tumor growth and angiogenesis by targeting integrin-beta8
MicroRNA-125a/b-5p inhibits endothelin-1 expression in vascular endothelial cells
MicroRNA-10a regulation of proinflammatory phenotype in athero-susceptible endothelium in vivo and in vitro


text:
今年の夏休みのプランを早く立てなくてはならない Continue Reading
House with an 80-foot pool
地中海を望むプールというのも悪くはないが、ビバリーヒルズの高台からL.A.のダウンタウンと太平洋が見渡せるプールにはかなわない、と、言ってしまったら、大勢の方から反論を受けてしまうかな Continue Reading
House in Yoga
When architects design their own homes, they don't want everything set in stone Continue Reading
Courtyard House
Accommodating two generations under one roof, a common housing situation in Japan, gives an additional facet to the design of a house Continue Reading
The House on Waseda Street
The width of this house is less than 11 feet in the front and even smaller in the rear (8'4″) Continue Reading
Emmanuelle Moureaux
Emmanuelle Moureaux, a Tokyo based French architect/designer, is adding some nice touches to the architectural design scene in Japan Continue Reading
Green Approach
A Short Break
Photo © Koichi Torimura (Green Path House)
We'll be back in a few days!
House of Light, 2000
This is a place worth staying if you are in Japan. House of Light by artist James Turrell and architect Daigo Ishii was constructed in traditional sukiya style, with a pillared verandah and gently slanting gabled and hipped roofs Continue Reading


text: General Meaning: A vine is very similar to seeing a tree in a dream or vision. It can speak either of blessing and prosperity or of a curse. You would need to sense the spirit on the dream or vision and interpret accordingly. • Positive: A vine speaks of the blessing of the Lord. Whenever the Lord gave a promise in the Word, He would promise to give each man a vine. • He also refers to Himself as the vine and us as the branches. It speaks of the blessing of the Lord, both spiritual blessings and natural blessings! (John 15:5 ) • The grapes from a vine are a result of each person playing their part. The grapes grow on the branches, not on the main stem. This is a picture of the fruit of the spirit in our lives. • Because the vine is a perfect picture of the church, the branches speak of ministries and our own Christian walk. As each branch feeds of the stem (which is Jesus) we will bear good fruit! • Negative: You can get a vine that does not bear fruit or that is wicked. This would refer to not going on with the Lord or even a curse. • A vine that does not bear fruit speaks of being lukewarm and not obedient to God's Word. According to Scripture, such a vine would be cast into the fire. • Speaking of Judgment • Luke 3:9 And now also the axe is laid to the root of the trees: every tree therefore which brings not forth good fruit is hewn down, and cast into the fire. • See also: Fruit, Grapes, Trees, Wine.


text:
Methods of tuning PID controller for stable first-order systems with dead time
Supervisor: doc. Ing. Jan Cvejn, Ph.D.
The aim is to compare the properties of several selected methods of setting parameters of the PID controller for static systems of the first order with dead time. The methods was compared using step response at selected examples. To simulate these methods the computational software MATLAB with simulation environment SIMULINK was used.
Application for UV-VIS spectra analysis
Applications for evaluating of data measured by specific analytical method. To be more specific, the application deals with the decomposition of the sum of the peaks to the individual peaks (it is assumed that the individual peaks are in the form of Gaussian curves). The expected output is Java application containing GUI, data visualization, import and export data and statistical evaluation of outcomes. In other words, it is the application of different optimization methods to a specific problem.
Search techniques for PID controller tuning
This bachelor thesis has been focused on the comparison of the advantages and disadvantages of control systems using the controller, which was set up both using classical methods, based on the continuous transfer function of system under control and the algorithm Nelder and Mead, based on the objective function. The objective function is composed of a control circuit in Simulink and its output value is the criteria that is relevant and provides feedback. Thus, the algorithm allows to find such parameters PID controller, which ensures minimal power control process.
Control of hydraulic device using Siemens Simatic programmable logic controller
This work solve method of controlling hydraulic system model, which was create in matlab. PLC configured via TIA Portal like bistable controller and PID controller. Communication between programs proceeds via OPC Server.
Small CNC milling machine
The work is focused on construction and controlling of CNC milling machines. The small CNC milling maschine was constructed and it allows the movement of spindle in 3 axes. The movement is secured by stepper motors and its rotational movement is transfered to shifting movement. Stepper motors are operated by ICs made by Thosiba. The whole controlling is secured by CNC-USB software, which is using controlling board with PIC type IC on it. The work is also focused on operations with software, specific milling machine construction and its functionality.
Design and construct a robotic manipulator
The present thesis dealing with the design and implementation of robotic manipulator, which is dedicated to creating hardware devices for handling objects in industrial automation. Bachelor thesis in the introduction of the theoretical part deals with electronics, which consists of two units. A separate control part is an application created in Java. The theoretical part of the thesis also highlights the issue of selecting the appropriate resources to development of the entire robotic manipulator. Bachelor thesis also explains the inner workings of the used software, developed in ANSI-C. At the end of the thesis are summarized used algorithms and at the same time there are submitted technical drawings of the entire robotic manipulator.
Bicross starting device remote unit
The aim of the following thesis is to build a starting device for bicross while simultaneously enabling control over a starting gate. It introduces the issue of micro controllers and explains how the latter command a pneumatic piston. The theoretical part contains an overview of all the options concerning the starting gate components, the air brake method, the method of connecting a pneumatic piston, as well as method of engaging the I/O ports. The practical part contains a proposal of I/O port attachment on the micro controller in order to co the starting gate. The control unit will be managed by two buttons, which will execute a given task.
Mathematical model of Humusoft CE151 process
This thesis focuses on creation of mathematical model, identification and verification of laboratory system of a ball on plane CE151. It is non-linear and unstable system. Experimental identification of static and dynamic model parameters will be done, followed by comparison of created model with real system.
Mathematical model of Humusoft CE152 process
The subject of this thesis is to construct a mathematical model of magnetic levitation system CE152. Further subject is to find unknown parameters of mathematical model with use of experimental identification. The assembled model is verified and compared with the real system. Compensation method is presented because of the non-linearity of the system example.
OpenPLC library functions motion control for S7-1500
Work is devoted to the issue of control of propulsion, using a programmable industrial -family S7-1500 machines. He was made a basic description of the programming environment of the TIA Portal V13, a description of the S7 programmable logic controllers-1500 and the instructions for the control. In the practical part of the universal program is created for the control of the drive.
Software for finding the optimal controller parameters
The challenge is programming an application to compare different methods to optimize the controller parameters selected structure. Selection of controller structure and its design. Brief research issues concerning different approaches to off-line respectively on-line optimization, evaluation of methods, the selection of a few of them and their verification on a simulation model of a dynamic system.
PID controllers tuning methods
The work is preoccupied mainly with the analysis of methods for setting PID regulators. Because this issue is very extensive, the first chapter is dedicated to the explanation of basic terms from the area of automation and regulation. It is essential to know these terms for the setting of PID regulators. There is also described the meaning of PID regulator for automation and his possible variation. Then there is defined the function of program, which is a part of this bachelor´s work.
Application for control of hot-air device in LabVIEW
Implementation of user friendly application for controlling, measurement and management of thermal dynamic system placed in laboratory in "G" programming language in LabVIEW. Connection of laboratory task to the computer via measurement card.
Program module for on-line optimization of parameters of a PID regulator
The objective of the thesis is writing a background research on optimization methods and choosing one of them for a practical realization. Matlab and Simulink are used for the realization of optimization and also two computers wired via two NI-USB 6008/9 cards using optimization algorithm in LabVIEW environment.
Simulation of dynamical systems with LabVIEW
This thesis is devoted to the use of LabVIEW in the simulation and modeling of dynamic systems and subsequent on control PID controllers using the Control Design & Simulation Module. The first chapter includes brief introduction to programming in LabVIEW and the second chapter is devoted to solving given systems. Part of this thesis are programmed applications.
Derivation and verification of an inverse pendulum math model
Supervisor: Ing. Pavel Škrabánek, Ph.D.
The work is dedicated to creating a mathematical model of the inverted pendulum. The model is derived from the force balance acting on the system. The model has been realized in the computing environment Simulink MATLAB. The identification of model parameters is the integral part of the work. The model has been verified by experiments on the real model.
Creating of a control software for a mobile robot platform
Supervisor: Ing. Pavel Škrabánek, Ph.D.
The aim of this work is to design and compare two approaches to identify the parameters of static characteristics with saturation. Both approaches are based on clustering methods; however, they differ in the concept of cluster creating. Naturally, the concepts affect the identification of static characteristics parameters, too. For this purpose will be created software, which will be processed experimentally measured data from several real devices. The evaluation of the experimental results is also considered in this work.


text:
Earl Grey. Hot. Make It So.
There's nothing technologically astounding about the teapot, right? Well, fancy a gander at the ones by English-born artist Margaret Realica currently on display in Alternate Images, an exhibit that provides a sculptural take on the mechanization of water.
Realica uses porcelain, Plexiglas, and found gears to fashion teapot-like fixtures that wouldn't look out of place on the Starship Enterprise. The pieces resemble little machines -- the Plexiglas squares and metal gears certainly give the impression of drawing liquid through a series of tubes -- but without the possibility of movement. The works are as static in form as they are in function. That's the point, of course. The teapots, with their thin, snakelike wires and puffy porcelain containers, almost beg for anthropomorphization. And in the same way we attach life to wind-up toys, cars, or any old mechanical thing, the idea of function is endearing. All it takes is recognition of form. Same with Realica's contraptions. You can't brew tea with em, but it doesn't take much suspension of disbelief to think you could try.
Tuesdays-Sundays. Starts: Jan. 25. Continues through March 2, 2008
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text: The hotel sprawls over 78 pristine beachfront acres and has terra cotta tile roofs, covered archways and wooden trellises lending it the understated, relaxed appeal of a true classic California resort. Guests have the most advanced modern conveniences and cutting edge technologies at their fingertips.Each one of the rooms and suites is luxurious, intimate and relaxed featuring a private patio or balcony. The en suite bathrooms are fitted with a shower, bath and hairdryer. Further in-room amenities include a direct dial telephone, satellite/cable TV, radio and individually regulated air conditioning and heating.


text:
Watch how to make this recipe.
Cook the pasta in a large pot of boiling salted water, until al dente. Drain well.
Season chicken with salt and pepper. Heat a large grill pan over medium high and add chicken. Grill until golden and completely cooked. Remove to a plate and slice.
Add the garlic and red pepper flakes to a saute pan with 3 tablespoons of olive oil and saute until fragrant. Add the cooked pasta and turn heat off. Mix all together.
Remove pasta to a large bowl. Add chicken to the warm pasta and season with salt and pepper. Sprinkle in chopped parsley. Add the juice of 2 lemons and mix. Before serving top with Parmesan.
Recipe courtesy of The Neelys
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