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93 - 107 Final
Bryant, Odom help Lakers top TimberwolvesNov 10, 2007 - 8:01 AM LOS ANGELES (Ticker) -- The post-Kevin Garnett era for the Minnesota Timberwolves has not gotten off to a good start. Kobe Bryant and Lamar Odom made sure it didn't get any better.
Bryant scored 30 points, grabbed seven rebounds and dished out seven assists and Odom added 18 points and 10 rebounds as the Los Angeles Lakers posted a 107-93 victory over the Timberwolves on Friday night.
Al Jefferson had 20 points and 10 rebounds for the Minnesota, which has started the season with four consecutive losses after dealing four-time All-Star forward Garnett in a blockbuster trade during the offseason.
"Kevin is gone," Jefferson said. "He is history. He's gone on with his career in Boston. We are trying to establish something here."
Bryant shot 9-of-19 from the floor, knocked down three shots from the arc and came away with two steals.
"We've just got to continue to work hard," Bryant said. "It's such a long season. We've got Lamar back now and that is a big step in the right direction and we just have to get the rest of the guys out there."
Odom, who was making his first appearance of the season following offseason shoulder surgery, played 41 minutes and brought an energy to the Lakers that they did not appear to have in their first four contests.
"I had Odom in and out of there a couple of times - gave him a break," Lakers coach Phil Jackson said. "He has great stamina and he played well tonight."
"Lamar looked great," Bryant said. "He didn't look tired. He looked aggressive, and it looked like he was in good rhythm."
The Lakers took control with Bryant on the bench in the second quarter, capping a 12-2 run with a 3-pointer from Vladimir Radmanovic to grab a 42-38 edge with 5:44 left in the second quarter.
Bryant had 14 points in the first half as Los Angeles took a 56-50 lead into the break.
The Lakers came out strong in the second half and burst out with a 12-2 run, which was highlighted by Lamar Odom's full-court pass to a wide-open Bryant for an easy layup.
"I thought the difference was the first five minutes of the third quarter," Minnesota coach Randy Wittman said. "LA came out and went on a 12-2 run to start the third. It put us in a hole that was too much to overcome."
Sebastian Telfair helped cut the deficit to 90-81 by scoring seven points in the first five minutes of the final session, but the Lakers did not allow the Timberwolves to get any closer than seven the rest of the way.
Three players that came to Minnesota in the Garnett trade led the way for the Timberwolves. The 22-year-old Jefferson has now had a double-double in each game this season, while Telfair chipped in 15 points and Ryan Gomes finished with 17.
"We missed a lot of short shots tonight," Gomes said. "They shot a lot more free throws than we did. Overall, we played a pretty good game. But playing well is not good enough when you don't win."
Both Chris Mihm and Andrew Bynum had 10 points and 10 rebounds on the night for Los Angeles, which made 41 trips to the free-throw line, while Minnesota had just 14 attempts.
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Telomere and ribosomal DNA repeats are chromosomal targets of the bloom syndrome DNA helicase
Bloom syndrome is one of the most cancer-predisposing disorders and is characterized by genomic instability and a high frequency of sister chromatid exchange. The disorder is caused by loss of function of a 3' to 5' RecQ DNA helicase, BLM. The exact role of BLM in maintaining genomic integrity is not known but the helicase has been found to associate with several DNA repair complexes and some DNA replication foci.
Chromatin immunoprecipitation of BLM complexes recovered telomere and ribosomal DNA repeats. The N-terminus of BLM, required for NB localization, is the same as the telomere association domain of BLM. The C-terminus is required for ribosomal DNA localization. BLM localizes primarily to the non-transcribed spacer region of the ribosomal DNA repeat where replication forks initiate. Bloom syndrome cells expressing the deletion alleles lacking the ribosomal DNA and telomere association domains have altered cell cycle populations with increased S or G2/M cells relative to normal.
These results identify telomere and ribosomal DNA repeated sequence elements as chromosomal targets for the BLM DNA helicase during the S/G2 phase of the cell cycle. BLM is localized in nuclear bodies when it associates with telomeric repeats in both telomerase positive and negative cells. The BLM DNA helicase participates in genomic stability at ribosomal DNA repeats and telomeres.
Bloom syndrome is caused by loss of function of a DNA helicase
Bloom syndrome (BS) is a rare cancer-prone autosomal recessive disorder characterized by genomic instability, immunodeficiency, infertility and small stature
BLM is localized in nuclear bodies and the nucleolus
The BLM DNA helicase is found in two distinct nuclear structures in normal human cells, ND10 or PML nuclear bodies (NBs), and the nucleolus
BLM helps to maintain genomic stability in the S/G2 phase of the cell cycle and associates with DNA repair proteins
The expression of the BLM DNA helicase is cell cycle regulated, showing a marked increase in S phase and peaking in G2 phase
Isolation of chromosomal sites where BLM is located
Proteins bound to DNA can be reversibly cross-linked as chromatin complexes by treating cells with formaldehyde
BS cells in long term culture have less rDNA and more variation in telomere repeats than normal cells
A normal (HG1522) and a BS (HG1525) lymphoblastoid cell line were grown in culture for one year and individual clones were generated as described previously
Figure 1
Analysis of rDNA and telomere repeats in normal and BS lymphoblastoid cell lines
Analysis of rDNA and telomere repeats in normal and BS lymphoblastoid cell lines. A. Diagram of experimental design
Table 1
Ribosomal DNA and Telomeric DNA in Normal and BS Cell Lines. Hybridization analysis of genomic DNA from normal (HG1522) and BS (HG1525) cloned cell lines for relative amounts of ribosomal DNA and telomeric DNA. The statistical values are shown for each data set. The data is normalized to the lowest value in each set.
Cell line
std. dev.
t value
P value
1522 rDNA
1525 rDNA
1522 TelDNA
1525 TelDNA
Mapping of BLM domains required for telomere association
A series of cell lines expressing GFP-BLM variants (Figure
Figure 2
BLM mutation map and telomere association domains
BLM mutation map and telomere association domains. A. Map of BLM mutations
This observation demonstrates that the region of BLM required for NB localization
The C-terminal domain of BLM directs it to two sites in the rDNA repeats
The rDNA genes in human cells have approximately a 15 kb coding region and a 28 kb non-transcribed spacer (NTS) where DNA replication forks initiate
Figure 3
Map of sequence elements in the human rDNA repeat unit and identification of the BLM association domains
Map of sequence elements in the human rDNA repeat unit and identification of the BLM association domains. A. The human rDNA repeat unit (U13369) sequence features and the location of the region isolated with a polyclonal BLM antibody. The orange arrows indicate sites of primer sets. The dotted lines indicate the direction of DNA replication origins
Purification and assay of GFP-fusion proteins
These studies indicate that deletion of the N3 and N4 domains of BLM have the greatest effect on telomere association, and the C1 and C2 domains are required for BLM to accumulate in the nucleolus. A recombinant baculovirus for each of these GFP-BLM proteins was constructed and expressed in Sf9 cells. The accumulation of the GFP-BLM proteins in the nucleus of Sf9 cells was similar to those seen in human cells (Figure
Figure 4
Expression and purification of GFP-BLM alleles in Sf9 cells
Expression and purification of GFP-BLM alleles in Sf9 cells. A. Fluorescent micrographs of Sf9 cells infected with recombinant baculoviruses expressing GFP-BLM deletion proteins constructed using methods described previously for the full length normal BLM
Standard helicase assays were performed using all of the purified proteins (Figure
Figure 5
Helicase activity of the GFP-BLM deletion proteins
Helicase activity of the GFP-BLM deletion proteins. A. Autoradiogram of the unwinding assay gel. The 0 lane contains no enzyme. The Δlane reaction was heated at 95°C for 5 minutes. The C2 reaction contains 1 ng protein and other reactions with the deletion proteins contain 25 ng. The normal BLM reactions contain the amounts shown in the right graph in panel B. Activities are reported relative to 8 units/ng DNA-dependent ATPase activity and 7 units/ng unwinding activity for normal GFP-BLM. B. Graphic representation of helicase activities relative to normal GFP-BLM. Assays were performed as described previously
Cell cycle profiles of BS cells expressing BLM alleles
The cell lines expressing the normal and altered BLM proteins were induced for two days as described before
Figure 6
Cell cycle assay of induced cell lines
Cell cycle assay of induced cell lines. Cell lines expressing GFP-BLM alleles described previously
Table 2
Cell Cycle Analysis of Induced Cell Lines. Fixed cells were stained with PI and analyzed for DNA content. The percentage of the induced population in each phase of the cell cycle are shown.
Cell Line
Formation of quadriradials in BS cells is favoured in gene dense chromosomes
One of the distinctive features found in lymphocytes from BS individuals are quadriradials or recombination figures involving homologs that occur in 1/100 metaphases from lymphocytes
Figure 7
Quadriradial formation and gene density
Quadriradial formation and gene density. A. Data from a study of 481 quadriradials found in BS lymphocytes
BLM participates in genomic stability at telomere and rDNA repeats
Aging and cancer are associated with changes in telomeres and rDNA
BLM in NBs associates with telomeres
Telomeres have specialized chromatin with several well characterized binding proteins and potentially form a variety of three-dimensional structures including G quartets and D-loops
Helicases are required for many DNA manipulation mechanisms and are deleterious when deregulated or mislocalized. The packaging of BLM into the NBs can regulate its activity as well as coordinate its arrival to sites undergoing DNA repair
Comparison of normal and BS lymphoblastoid cell lines demonstrates that the BS cell lines have a greater variance in the amount of telomeric DNA relative to the normal. This observation suggests that BLM is not required for telomere synthesis or function but rather helps to limit the amount of telomeric DNA. A simple model for BLM or other RecQ family DNA helicases at telomeres would be to process the 3' end of the telomere tail sequestered in the D-loop structure as has been suggested for the MRE11/RAD50/NBS complex
BLM is found where forks originate in the rDNA repeat and may participate in the initiation of DNA replication in the rDNA
The ribosomal DNA repeat in eukaryotic cells is replicated in a unique manner. Replication forks initiate at multiple sites in the NTS region and terminate at the same region as rRNA transcripts such that forks do not oppose transcription activity
DNA replication, recombination and repair pathways work together to maintain genomic integrity
Chromosomes replicate in a mosaic manner with euchromatin replicating early and heterochromatin replicating late in general
This study isolates telomere and rDNA repeats by chromatin immunoprecipitation with anti-BLM. Hybridization experiments using deletion alleles of GFP-BLM demonstrate that the N-terminal (NB localization) domain of BLM is the telomere association domain, and the C-terminal domain (nucleolar localization) domain is the rDNA association domain, directing BLM primarily to the NTS. BS cells in long-term culture have less rDNA and more variability in telomere repeats than normal cells. Cell lines expressing BLM proteins deleted in the telomere and rDNA association regions have altered cell cycle profiles. BLM localized in NBs associates with telomere repeats in telomerase positive or negative cells. These studies suggest a role for BLM-containing complexes to untangle rDNA repeats in the nucleolus in S phase and at telomere repeats in S/G2/M as a participant in NB-mediated DNA repair. These studies suggest that the localization of BLM as well as its enzymatic activity affects genomic stability.
Cell lines
Fibroblast and lymphoblastoid cell lines used for ChIP were obtained from the Coriell Cell Repositories: Normal human lung fibroblasts AG06814 (WI-38), BS skin fibroblasts GM02932B (
Chromatin immunoprecipitation
Fibroblast cell lines were grown as described before
DNA cloning, sequence analysis and websites
The purified DNA fragments were visualized on a 1% agarose gel to verify recovery of 200–600 bp products and cloned into the pCR 2.1 TOPO vector using the TOPO TA Cloning kit (Invitrogen). Plasmid inserts were sequenced directly or after PCR amplification with the M13 primers supplied in the cloning kit using an ABI BigDye Terminator v3.0 kit and an ABI377 sequencer.
Sequences were screened for repeated sequence elements using Repeatmasker2
Linkers and primers
Invitrogen synthesized oligonucleotides. Linkers for ChIP clones:
5'-TACGTGCGATAACGAGCGAGTATCGTC-3'/5'-GACGATACTCGC-3' or 5'-ATGCACGCTATTGCTCGCTCATAGCAG-3' / 5'-CTGCTATGAGCG-3'. Primers for amplifying plasmid inserts:
Ribosomal DNA primers:
1 kb 5'-CTCTGCCGCGATCCTTCT-3'/5'-GGGAGCCGGAAGCATTTT-3',
16 kb 5'-ATGTATCGAAGCCCCATTTC-3'/5'-GGCCCCAAAAGAAAAGAAAA-3',
19 kb 5'-GTGTGTTGGGGCTGAAAACT-3'/5'-CCTCCTCAAACGCAAGAAAG-3',
27 kb 5'-TGTTGGCTTGTTTTGTTTCG-3'/5'-AAACATCAACCGGCTCTCAC-3',
34 kb 5'-GACAACTCACGCCCTAATGC-3'/5'-ATCCTCCGAAAGAGGTTGCT-3',
37 kb 5'-AGGAGTCCCCTGGTCTGTCT-3'/5'-GTCAAGGTCCAAACCGAAAA-3',
42 kb 5'-GATGGTGGCGTTTTTGGG-3'/5'-CGACTCGGAGCGAAAGATATA-3'
4 kb primers were supplied by Perkin-Elmer and included in the kit for rRNA quantitation (see below). Oligonucleotide primers for PCR were chosen using the primer3 Website at MIT
The molecular beacon and primers for quantitating the recovery of genomic DNA using the Alu-Sb2 elements were made by Research Genetics and used as described
Baculovirus Constructions
BLM alleles were constructed by replacing fragments of the full-length normal cDNA construction with the deleted ones described before
Purification of GFP-fusion proteins and helicase assays
Full length and deleted BLM proteins were expressed and purified as before
Cell cycle analysis
SV40-transformed BS fibroblasts containing different BLM alleles
List of abbreviations
ALT alternative telomere synthesis
BS Bloom syndrome
ChIP chromatin immunoprecipitation
FACS fluorescence activated cell sorter
HRD helicase and RNAseD
NB ND10 or PML nuclear body
NTS non-transcribed spacer
PBS phosphate buffered saline
PI propidium iodide
rDNA ribosomal DNA
SCE sister chromatid exchange
SDS sodium dodecylsulfate
Authors' contributions
Author 1 JS performed the FACS analysis, the DNA cloning and sequencing of the lymphoblastoid fragments, expression and purification of the GFP-BLM fusion proteins and participated in the helicase assays. Author 2 EP carried out the chromatin immunoprecipitation, DNA cloning and sequencing of the fibroblast fragments, the PCR analyses, and performed ChIP on the Tet-on cell lines. Author 3 NN participated in the isolation of the recombinant baculoviruses, protein purification, and helicase assays as well as performing the hybridizations and drafting the manuscript. All authors read and approved the final manuscript.
The authors thank Alfred Prince for use of the ABI7700, Dong-Hun Lee for help with the TaqMan assays and Linda Andrus for the Alu-Sb2 primers and beacon. Susana Albano Maraia and Pablo Rubinstein provided assistance with the DNA sequencing. Jill Storry provided advice and reagents for the cloning. Ruth Croson-Lowney and Karina Yazdanbakhsh helped us with the FACS study. We gratefully acknowledge the suggestion of a reviewer of our previous BMC Cell Biology publication to look at the cell cycle profiles of the cell lines. The Elsa U. Pardee Foundation and NYBC provided funding for this study.
Bloom syndrome: a Mendelian prototype of somatic mutational disease
Bloom syndrome
The Bloom's syndrome gene product is homologous to RecQ helicases
The DNA helicase activity of BLM is necessary for the correction of the genomic instability of Bloom syndrome cells
The Bloom's syndrome helicase unwinds G4 DNA
The Bloom's syndrome gene product promotes branch migration of holliday junctions
Binding and melting of D-loops by the Bloom syndrome helicase
The Bloom's and Werner's syndrome proteins are DNA structure-specific helicases
PML is critical for ND10 formation and recruits the PML-interacting protein Daxx to this nuclear structure when modified by SUMO-1
Nuclear structure in normal and Bloom syndrome cells
Structure, organization, and dynamics of promyelocytic leukemia protein nuclear bodies
Pondering the promyelocytic leukemia protein (PML) puzzle: possible functions for PML nuclear bodies
Review: properties and assembly mechanisms of ND10, PML bodies, or PODs
Nijmegen breakage syndrome disease protein and MRE11 at PML nuclear bodies and meiotic telomeres
A new spectrin, beta IV, has a major truncated isoform that associates with promyelocytic leukemia protein nuclear bodies and the nuclear matrix
Alternative lengthening of telomeres in mammalian cells
Localization of the Bloom syndrome helicase to punctate nuclear structures and the nuclear matrix and regulation during the cell cycle: comparison with the Werner's syndrome helicase
Cell cycle regulation of the endogenous wild type Bloom's syndrome DNA helicase
The C-terminal domain of the Bloom syndrome DNA helicase is essential for genomic stability
Colocalization, physical and functional interaction between Werner and Bloom syndrome proteins
BASC, a super complex of BRCA1-associated proteins involved in the recognition and repair of aberrant DNA structures
Replication protein A physically interacts with the Bloom's syndrome protein and stimulates its helicase activity
Potential role for the BLM helicase in recombinational repair via a conserved interaction with RAD51
Association of the Bloom syndrome protein with topoisomerase IIIα in somatic and meiotic cells
The Bloom's syndrome protein (BLM) interacts with MLH1 but is not required for DNA mismatch repair
Genome-wide location and function of DNA binding proteins
Initial sequencing and analysis of the human genome
Molecular evidence that homologous recombination occurs in proliferating human somatic cells
Stabilized viral nucleic acids in plasma as an alternative shipping method for NAT
Initiation and termination of DNA replication in human rDNA genes
The three-dimensional structure of the HRDC domain and implications for the Werner and Bloom syndrome proteins
Chromosome territories, nuclear architecture and gene regulation in mammalian cells
Difference in the localization and morphology of chromsomes in the human nucleus
Localization by Q-banding of mitotic chiasmata in cases of Bloom's syndrome
Mitotic chiasmata, gene density and oncogenes
Telomeres and telomerase in aging and cancer
Telomeres, the nucleolus and aging
Mitotic recombination and segregation of satellites in Bloom's syndrome
Protection of mammalian telomeres
New ways not to make ends meet: telomerase, DNA damage proteins and heterochromatin
The Bloom syndrome helicase BLM interacts with TRF2 in ALT cells and promotes telomeric DNA synthesis
Telomere-binding protein TRF2 binds to and stimulates the Werner and Bloom syndrome helicases
Structure, subnuclear distribution, and nuclear matrix association of the mammalian telomeric complex
Regulation and localization of the Bloom syndrome protein in response to DNA damage
Cell-cycle-regulated association of RAD50/MRE11/NBS1 with TRF2 and human telomeres
Bloom's syndrome protein is required for correct relocalization of RAD50/MRE11/NBS1 complex after replication fork arrest
Chromatin structure and transcription
Analysis of the replication pattern of Chinese hamster chromosomes using 5-bromo-deoxyuridine suppression of 33258 Hoechst fluorescence
Late DNA synthesis in heterochromatin
Human DNA polymerase epsilon colocalizes with proliferating cell nuclear antigen and DNA replication late, but not early, in S phase
Bacteriophage T4 gene 41 helicase and gene 59 helicase-loading protein: a versatile couple with roles in replication and recombination
DNA recombination: the replication connection
The nonmutagenic repair of broken replication forks via recombination
RecQ and RecJ process blocked replication forks prior to the resumption of replication in UV-irradiated Escherichia coli
The function of xenopus Bloom's syndrome protein homolog (xBLM) in DNA replication
Drosophila BLM in double-strand break repair by synthesis-dependent strand annealing
The Saccharomyces cerevisiae WRN homolog Sgs1p participates in telomere maintenance in cells lacking telomerase
SGS1, the
The human Bloom syndrome gene suppresses the DNA replication and repair defects of yeast dna2 mutants
BLM (the causative gene of Bloom syndrome) protein translocation into the nucleus by a nuclear localization signal
Chromatid exchange in Bloom's Syndrome cells

subset: commoncrawl


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Whenever I think to shop online, I always give my first preference to Amazon than others. It is so because it offers product at cheaper prices than snapdeal or flipkart. (Help a friend and save Rs50)
To add millions of new customers, Amazon has started "Refer and Earn Program." Now we see how does it works?...............................................CONTINUE READING


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WOOL MODERN WAISTCOATCharcoal
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Family Law
Family Law Questions? Ask a Family Lawyer Online.
The move I am considering would not affect our current parenting schedule. Are there other objections my ex could raise that the court would consider? His mother has a POA from him and they have a lawyer taking care of his legal issues with his second ex wife. While deployed, can this lawyer take me to court if my ex decides that he objects to my moving?
Hello again and thank you for your reply. Well, there could always be objections and I couldn't really foresee them all since I don't know the complete situation, but you are right in thinking that visitation or parenting schedules are usually the biggest issue. But, for example, the ability to attend school or sporting functions, doctor's appointments, and just flexibility of being close in case of an emergency are generally some of the issues. He could,theoretically, ask his attorney to file an injunction once he gets your notice, but his mother could not use a POA to make those decisions. However, the way the SCRA reads is that he doesn't have to have an attorney step in now if he is deployed. He has the right to not have to deal with the issue until he returns from deployment.


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A new survey has provided an indication of the broadband speeds Brits see as necessary for the typical household.
Carried out by cable.co.uk, the poll gauged the opinions of nearly 300 people on what they consider the minimum level of connectivity required at present. More than half of respondents pointed to somewhere between eight Mbps and 50 Mbps as the base speed.
Just under one in four people (24.75 per cent) said they think the minimum connection should be over eight Mbps, but less than 20 Mbps. A further 30.17 per cent claimed the necessary speed should be higher than 20 Mbps, but lower than 50 Mbps.
Only one per cent of respondents said they see two Mbps as an acceptable basic level of connectivity. This is currently the government's universal service commitment for broadband and suggests the coalition may be somewhat out of sync with the public on this issue.
Some 8.8 per cent of people cited between two Mbps and eight Mbps as the necessary minimum speed, while 15.9 per cent said it should be more than 50 Mbps, but less than 150 Mbps.
Only five per cent claimed connectivity of up to 1,000 Mbps is required, while 14.24 per cent think speeds of a gigabit or more per second are needed, even though this is unlikely to be widely availble anytime soon.
The satellite broadband technology provided by Avonline delivers speeds of up to 22 Mbps, which is more than sufficient for the vast majority of popular online activities, including video streaming and downloading films.
It can provide these speeds anywhere in the UK so long as the sky is visible, meaning residents of remote rural areas can access a level of connectivity that simply isn't possible otherwise.
According to Ofcom, the average broadband speed in the UK is 18.7Mbps. However, this figure is likely skewed by the minority of high-speed services in urban areas and many people across the country are relying on connections that are much slower.


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According to the American Heart Association, September is National Childhood Obesity Month. With a rising childhood obesity rate and heart disease being the No. 1 killer in the capital area, it is time to take notice.
Healthy diets are not only important for adults but imperative for children. Introducing good habits at an early age provides a foundation for a healthier life for that child.
As a community, we need to make a commitment to the youth of our area and long-term health. We need to walk away from foods low in nutritional value and high in calories and put down the sugar-sweetened beverages for water. We need to create a community founded on the idea that fruits, vegetables, lean protein, whole grains and low-fat dairy are the easy choice.
We as a society are slowly acknowledging this problem; however, more of us need to become involved. As adults, we need to take an active role in our children's daily eating habits by providing healthy foods on our children's plate each day and by being healthy-eating role models.
Debra Lockwood
Provident Senior Living Resources
Baton Rouge


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text:
Would you like to save as your currency permanently or for this visit only?
I arrived late( 2Am), but staff was very kind. And when I leave early morning, staff arrange my breakfast.
Very comfortable, modern hotel with sleek design and spacious rooms. Relaxed atmosphere, lovely breakfast. Obviously Norway is an expensive country compared to the rest of Europe even, but the price we got was quite reasonable. No major complaints. We arrived very late and left fairly early.
Very nice location on Tyrifjord, spacious and comfortable, good service. Good restaurant service at reasonable prices, and food available at convenient times. Loved watching the ducks come in in the evening. Very convenient to Krøderbanen which provided a great day's outing. Hotel's website says they charge NOK125 for 24 hours of wi-fi access, but in fact they were able to supply this service free of charge. Would have liked tea and coffee making facilities in the room.
Room with view to lake (or is it fjord ?), room with balcony, around peaceful and quiet and in the middle of nature.
Nice place and clean room, quiet. Good location near the fjord. Huge breakfast with lot of choice. Jj Bed little bit too small.
Breakfast was good. Old stinking rooms.
Beautiful location, particularly the rooms with a lake view, An excellent place for relaxation and a good night's sleep. Quiet and pleasant atmosphere
Great location, the staff was very kind. And the food was just perfect. I will certainly come back again to norway, and perhaps even to Tyriford Hotel.
Very nice hotel with view over adjacent lake and countryside, with many attractions in the area. Very relaxing.
very nice relaxed atmosphere, excelllent dinner ----
Everyone was nice and especially the breakfast staff. The hotel is also very quiet and very peacefull for late and lazy mornings.
Proximity to business district in Sandvika Windows opened to inner atrium of hotel - claustrophobic and airless - much prefer windows to outside of any building. Facilities good but a steam iron in room would be much preferable and more effective than a hot iron - also it was awkward with too short a cord threaded through ironing board. Who ( I ask ) is really going to steal an iron?? The room coffee maker had no operator instructions in English and I had no enjoyable coffee among several attempts - too much technology not enough basic good facility like a kettle and sachets of coffee. This technology glitch extended to the restaurant facility 2 mornings out of 3 when the coffee machine failed and I had to miss coffee again.
First experience is with the receptionist who was very rude insisting I had not paid for both nights. I actually did not stay there, but had a friend from Germany, and this was handled in such a way that is caused much embarrasement for me and my guest. Will not choose Thon hotel in the future when my friend comes next month.
very good breakfast and good location the room was too hot!!!! we hurry out as soon as possible. next time we deffenently want a room with a window........
A person who I was meeting with, was arriving late & I was able to arrange some food to be in his room when he arrived. (Past resteraunt closing time)
It had a good location, handy for shops and transport links at local bus and train stations. The reception staff were very helpful. More variety for cooked breakfast.
The foyer is amazing, very attractive, and the facilities generally are very nice. We found the staff helpful and pleasant. The food in the restaurant was excellent, especially the breakfast in the morning. There is a lovely walk from the hotel down around the bay and up into the town. The hotel is also incredibly close to what we were told was, the largest shopping mall in Scandinavia. It was about 10klm from the centre of Oslo and about 80 from Oslo Torp airport. Transport from the airport to the hotel and vice versa was very expensive. There are only 2 computers that are available for access which meant it was often difficult to find one to use, and when you were on you were frequently harrassed by other people.
Very comfortable bed. Spacious room. Friendly helpful staff Poor (temporary) breakfast facilities
there is an amazing island nearby it's in between several noisy motorways.
staff was amazing. the views are amazing. It is far from the airport. Probably have to pay $200 with taxi to get there but worth the money.
Beautiful location. Rooms were very nice. Staff was friendly and helpful. Breakfast was great. Tight spaces driving in but we always found parking.
The open dining area with coffee and waffles, available during the afternoon, was a nice touch. The fact that all meals were included in the price was good, too. Limited choice of evening meal - just one hot course. Internet use needed WiFi scratch cards (which had to be collected from reception each morning and evening) - free, so why scratch cards?
We found the member of staff on reception Lasse very helpful and polite it was also very nice having a buffett at the hotel FOC after a long journey. Would have liked a bigger bed
- Hard to find. Address not available on TomTom GPS. Parking very expensive. NOK 23,-/hour during both night and day... Nice, but really small rooms.
Easy to do Expensive for the type of hotel (eg very small and with no facilities).
Coffee and tea at the room! Much noise, no individual thermostat in the room ( it was either hot or cold in the room), simple breakfast
The hotel was nice and the staff were very helpful No bad points really, just that for a british traveller the price is eye- wateringly expensive.
Breakfast very good choice, however the cooked items were cold, pillows were good The was not compleley refreshed during the day, and there used shampoo bottles left in the shower rack
It was a functional hotel. I appreciated that you could bring dogs and especially without paying extra fees.
Very convenient location for the centre of Drammen. The decor of the restaurant and bar area was very nice. Breakfast was excellent with a very wide range of offerings. No tea and coffee making equipment in room.
That it was located near the city centre + the price was not too bad. And the breakfast buffet is really nice! The hotel is a kinda old, and looks a bit "worn down".
There was a good standard of food in the restaurant, especially for evening meals. Only one person on the front desk - had to wait, when checking out, for the phone to be answered (a 5 minute call from somebody needing information that had to be looked up, and then a booking).
location and access from highway when traveling by car entrance/hallways area somewhat run down
Good and silent. Polite service. Good breakfast. The girl in the reception mixed the rooms: She gave the bed for two to our friends (Men, normal) and separated bedt to me and my vife!
Excellent breakfast - far better than expected, both choice and quality. Staff in the hotel was nice and responsive. Location is good. Hotel needs renovating - rooms are a bit worn out. Bathroom infrastructure was old: it took minutes to get the shower water temperature correct - and it kept varying also after that. One of our rooms had a really smelly bathroom - another room was offered, though - hotel staff was responsive and created solutions for the customer. Air conditioning would be a must - this hotel did not have that.
showers in 2 rooms flooded the floor
Nice staff. Good food. Small room.
the landscape and the courtesy of housekeeping staff. the room was way to small, nearly no space between my side of the bed and the wall. the bathroom was incredible small as well, and the shower did not work properly. breakfast was not that fresh as expected.
wonderful organic breakfast lights in bedroom didn't work properly
The gas fire in the breakfast room was the best feature of the hotel. Asking for a 500 NOK deposit when I paid in cash. This was to "cover the trashing of the room" but at the check out the room was not inspected. I was ready to pay in full at arrival, but still wouldm have needed to pay deposit. So we settled on the 500 only. Weird.
There was no food available until after 21:00 because the kitchen was busy with a big function on Saturday night and the kitchen was closed on Sunday night.


text:
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text:
Hurricane Nicole hits Bermuda
CBS News Videos•
Hurricane Nicole lashed Bermuda with heavy rain and high winds. But a protective reef saved the island from a potentially deadly storm surge. Despite the fierceness of the storm, most of the damage was limited to downed trees and some flooding. Don Dahler reports.


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Breaking: Boehner to caucus: We'll move our own bill today
10/15/2013 9:43:36 AM Ed Morrissey
44 Comments
Does John Boehner have a card left to play? Faced with an angry group of Tea Party members in his caucus over the deal floating in the Senate, Boehner told House Republicans that he will move a new bill to the floor today for a vote. What will he pose
NSA collects e-mail address books in Internet surveillance
10/15/2013 9:21:50 AM Ed Morrissey
14 Comments
Remember when James Clapper and Keith Alexander insisted in Congressional testimony that the NSA didn't collect e-mail data from Americans? Good times, good times. The Washington Post Barton Gellman and Askhan Soltani reported last night that the
Panetta: This crisis shows a lack of leadership in the White House
10/15/2013 8:41:00 AM Ed Morrissey
44 Comments
Leon Panetta spent plenty of time in the Obama administration, first as a surprisingly effective CIA Director and later as Secretary of Defense, until Chuck Hagel took over this year. Panetta previously worked for Bill Clinton during his first term as
Will the Senate deal fly with the House rank and file?
10/15/2013 8:01:12 AM Ed Morrissey
72 Comments
Today appears to be Deal Day, when the Senate leadership in both parties hammers a way out of the budget impasse that avoids the October 17th debt-ceiling deadline and puts an end to the two-week federal government shutdown. The negotiators already have
Do You Have $25,000 or More in a Retirement Account?
You're likely getting shortchanged with your current IRA or 401(k). Most Americans report annual portfolio returns maxing out at 5% to 12%. But thanks to a new kind of retirement plan, over time you could see jaw-dropping returns up to 6 to 21 times higher than most investors… no options involved. Find out how right here.
Quotes of the day
10/14/2013 10:01:13 PM Allahpundit
287 Comments
So two weeks in, here's where we're at: Many and perhaps most users can't even get into the federal exchange system. Those who can are often stymied by errors, and can't trust that any subsidized insurance prices they see will be accurate. And then, even
Good news: New season of "Walking Dead" promises many more scenes involving bad child actors
10/14/2013 9:11:38 PM Allahpundit
67 Comments
To cleanse the palate. At this point they could move to an all-child cast ("Bugsy Malone" with zombies?) and the juggernaut would likely still roll on: In A18-49 demo, THE WALKING DEAD season premiere scored an incredible 8.3 rating. Bigger
Krauthammer vs. Will on emerging fiscal deal
10/14/2013 8:21:05 PM Mary Katharine Ham
90 Comments
So, what's in this deal? The basics, from NRO: Senate Leaders Harry Reid (D., Nev.) and Mitch McConnell appear to be close to a deal that would reopen the government and raise the debt limit. Reports indicate that the (not yet finalized) agreement
Europe cutting back on green-energy "investments" while coal makes a comeback
10/14/2013 7:31:38 PM Erika Johnsen
19 Comments
Once upon a yesteryear, various European and Asian governments as well as the United States seemed so unequivocally convinced that all the expensive and taxpayer-funded "investments" they were making in new, market-resistant, and so-thought
States already battling/warning against imposter ObamaCare websites, fraud
10/14/2013 6:41:33 PM Erika Johnsen
32 Comments
The creation of just about any gigantic welfare program has a reliable potential for creating a correspondingly gigantic opportunity for fraudsters — and ObamaCare is looking like no exception, with a vengeance. Federal and state officials as well
ABC/WaPo poll: Disapproval of handling of budget talks continues to climb for Obama, congressional GOP
10/14/2013 5:51:45 PM Allahpundit
61 Comments
Noteworthy in that it contradicts the least believable result from the big WSJ/NBC poll . That one had Obama's overall job approval increasing slightly after the shutdown, from 45/50 to 47/48. Not so, says, ABC/WaPo, which puts public approval of
Video: School punishes teen for acting as designated driver
10/14/2013 5:01:27 PM Ed Morrissey
100 Comments
It's not as if Erin Cox arranged to be the designated driver ahead of time for her friends so they could drink, either, or that she imbibed herself at the party. The senior and now-former captain of the volleyball team got a call from her friend
Gibbs: This ObamaCare rollout has been "excruciatingly embarrassing"
10/14/2013 4:11:28 PM Erika Johnsen
57 Comments
I'd say this just about confirms it: The rollout of the Patient Protection and Affordable Care Act has been administrated so incredibly poorly as to render all attempts at spin-doctoring pretty much futile. This is excruciatingly embarrassing for
Video: Does Cory Booker actually live in Newark?
10/14/2013 3:21:11 PM Ed Morrissey
58 Comments
No one's really sure at the moment, because as the Daily Caller notes, no one has seen him at his declared residences in quite a while. That would put an uncomfortable twist on the Senate race in the Garden State, which Booker has dominated since
The Ed Morrissey Show: Former FEC Commissioner Brad Smith, Jeff Dunetz
10/14/2013 2:51:13 PM Ed Morrissey
0 Comments
Today on The Ed Morrissey Show (4 pm ET), former FEC Commissioner and co-founder of the Center for Competitive Politics Brad Smith joins us for the first time to discuss the Supreme Court's upcoming look at McCutcheon v FEC, which may overturn more
Obama to markets: If we don't start making progress soon, "we stand a good chance of defaulting"; Update: Meeting postponed; Update: Tentative deal reached?
10/14/2013 2:31:07 PM Allahpundit
290 Comments
A little something to put you in the right frame of mind for that big Dem/GOP kumbaya meeting at the White House at 3. He tried to panic the markets to increase his leverage two weeks ago and it didn't work; two weeks later, with Reid and McConnell
Supreme Court to decide on Michigan affirmative action fight — again
10/14/2013 1:41:17 PM Erika Johnsen
35 Comments
Back in the 2003 case of Grutter v. Bollinger, the Supreme Court decided in a 5-4 vote that the University of Michigan Law School could indeed grant admissions preferences to minority applicants in the interests of fostering diversity on campus —
Report: Reid offers McConnell deal that would end fiscal standoff
10/14/2013 12:51:05 PM Allahpundit
139 Comments
The terms: Government re-opens and is funded until mid-December, debt ceiling is raised for another six to nine months, and Democrats maybe agree to repeal ObamaCare's medical-device tax and reinstate anti-fraud measures for O-Care applicants
If you think the ObamaCare exchanges and premiums were bad …
10/14/2013 12:01:27 PM Ed Morrissey
127 Comments
… then Barack Obama's hometown newspaper has news for you. The initial shock of the premium increases and the incompetent use of $94 million [see update] to create the world's biggest 404 exchange are just the starting shocks of
Exciting new high-tech solution to ObamaCare website disaster: Paper applications
10/14/2013 11:21:44 AM Allahpundit
97 Comments
Actually, my headline's incorrect. "Solution" suggests that people are now being successfully enrolled via paper applications. Not so. Turns out that the info on those applications needs to be input into the same wheezing, error-riddled
Video: EBT "glitch" sparks run on Walmart shelves in Louisiana
10/14/2013 10:41:46 AM Ed Morrissey
163 Comments
My, these "glitches" sure do get expensive these days, huh? A computer outage that impacted food-stamp operations in 17 states kept many low-income Americans from buying groceries this weekend: People in 17 states, including Maryland and


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Accommodations in GasconesSee All
This is a comprehensive travel guide for Gascones in Spain. From budgeting tips to finding the best spots, this travel guide has got all the insider information to explore Gascones like a local. The nearest major city to Gascones is Madrid. Take a short trip from Gascones and set some time aside to explore the Madrid. Dotted with places like Museo Nacional Del Prado, Parque Del Retiro, Madrid Cable Car; it will definitely be a good idea. A holiday in Gascones can generally be of 1-2 days.
Yes,it is that simple really! Enjoy your trip! Keep travelling!
Explore the best journey planner for your visit to Gascones and create a flawless plan in few simple steps!


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Best Of :: Food & Drink
Come in the morning or late afternoon, and Vishnu looks like any of the other anonymous businesses in this monochromatic John Wayne-adjacent office park: unremarkable. But when the lunch hour strikes, it begins. First, you see a trickle of people, then, all of a sudden, a crowd as thick as what you'd find at a Mumbai train station at rush hour shows up. The space is probably not intended for this many people, but they swarm anyway for a lunch buffet that includes freshly made dosas, curries, two kinds of biryanis and vadas (fried morsels that crunch like falafel). Along with Harry's Deli down the road, Vishnu has secured its cult status without much advertising. Ask the people in line ahead of you, and they'll tell you they found out about the place the old-fashioned way, by word-of-mouth, through friends who took them here, saying "You need to come check out this Indian place with me."
Seven small tables, one of them covered with cookies, pastries and other Filipino desserts in plastic boxes. Not a single white face in the place. All good signs you're going to be eating the real deal. Go to the counter and tell the woman behind the glass what you want. Served turo turo (cafeteria) style, she drops two huge scoops of rice on a plate and looks at you patiently while you try to decide. Two large barbecue pork skewers, generous with smoky, flavorful meat, not too fatty? Or kaldereta, a hearty, chunky beef stew with bell peppers, chile and other veggies? Beef mushroom overflowing with large sliced mushrooms and slices of beef reminiscent of boeuf bourguignon? The calamares is a little more of an acquired taste for a white palate, but the tender squid is cooked in its own delicious, salty ink.
If you'd like to get away from the standard artery-cloggers posing as fast breakers 'round town, the Blue Frog Bakery's Vegi-Burrito will stuff your gut without stopping your heart. The O'Brian potatoes, scrambled eggs, avocado, zucchini and tomatoes stuffed into a large tortilla is a two-fister topped off with a side of salsa perfection. If cholesterol isn't an issue, the breakfast machaca's shredded beef, eggs, bell peppers and onions or the insidiously addictive Egg Muffin Breakfast—scramblers, meat and cheese on an English Muffin—beats the hell out of any fast-foody junk you'd pick up elsewhere. The inside can get full quickly some mornings, so get in early and snake out one of the four small café tables under the Bakery's eave. Catch up on your reading, drink a latte and start your day with a full stomach (and mind). Inside tip: If you're into anime or all things nerdist, chat up friendly and funny counter girl Red. She's our favorite.
"This is my favorite bar that isn't a bar," says a regular inside Left Coast Brewery's tasting room as he sets down two empty growlers and sits at the bar. He picks up a pint glass with the brewery's logo on it and asks if it's the biggest glass they have. It is. You can taste whatever's chalked on the brew board in 5-, 10- or 16-ounce vessels. As the bartender fills the guy's glass with Left Coast Baltic Porter, there's a general discussion about how to pour a black and tan and which Left Coast selections would make one best. Everyone happily disagrees. The guy loves his porter so much he says he'd pour it over ice cream, which leads to a unanimous desire for a stout float. It's Saturday afternoon, and people flow in to get their growlers filled, and all of them stay to have a big glass of something barrel-aged (not available to-go) or dark or hoppy or even double-hoppy—Left Coast claims it's one of the pioneers of the double IPA. Its version is an award-winner called Hop Juice that lures you in with a sweet maltiness, then delivers a multihop wallop of fun bitterness, followed not too long after by the full-body effects of its 9.7 percent ABV.
Whichever individual 5-inch pies you choose at this Aussie newcomer, comfort food meets up-to-the-minute freshness and inventiveness. "Shortcut pastry shell with a puff-pastry lid" is how Pie-Not describes the perfect enclosures for the tender, juicy fillings. The Dog's Eye is the place to start, a ubiquitous meat pie Down Under; it's like having the best tomato-basil-mozzarella panini of your life at a Rome train station. The filling comes in many lively variations: two we liked are Shroomin, with crimini and field mushrooms, and the premium Drover, which has petite peas and carrots, topped with garlic mashed potatoes instead of the puff pastry.
The fresh peach pie is a mountain of sliced-fruit perfection altered only enough to be called pie.


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Rowing Australia has poached highly regarded British coach Simon Cox from Switzerland to head up its heavyweight sweep program for the Rio Olympics.
A finalist in last year's international coach of the year award for revitalising Swiss rowing, Cox's acquisition is a major boost for an Australian squad which underperformed in 2014.
Australia failed to win an able-bodied gold medal at this year's world titles in Amsterdam, which is a concern two years out from the 2016 Rio Games.
But their on-water disappointment has been tempered by off-water efforts.
RA performance director Chris O'Brien interviewed Cox at the world titles and his success has turned the tide after watching Australian coaches - such as Noel Donaldson and Peter Shakespeare who defected after the 2012 Olympics - thrive overseas.
Fellow Australians Paul Thompson (Britain) and Brian Richardson (Denmark) are also key coaching figures for rival nations.
Head coach in Switzerland since 2008, Cox helped the European nation gain their best results since 1999 by splitting his 2012 lightweight men's four crew and guiding them to medals at the 2013 world titles in the pair and double-sculls.
"I have thoroughly enjoyed my time with Swiss rowing but it is now time for a new challenge and being a part of the group that aims to make the Australian rowing team the best in the world," he said.
Cox will be based in Canberra at the AIS and have an overarching role in charge of the heavyweight sweep boats for men and women, assisted by Bill Tait.
The former British lightweight world champion is also set to coach the men's pair next year, which is likely to be given priority over the eight behind the premier men's four which won silver at the 2012 London Games.


text:
The SQLite package is a software library that implements a self-contained, serverless, zero-configuration, transactional SQL database engine.
This package is known to build and work properly using an LFS-8.0 platform.
This package is known to build and work properly when built with gcc-7.1.
Download (HTTP): http://sqlite.org/2017/sqlite-autoconf-3190300.tar.gz
Download MD5 sum: c93070d5bf136ce271db23d2dfbc2435
Download size: 2.4 MB
Estimated disk space required: 48 MB (with docs)
Estimated build time: 0.4 SBU
Optional Documentation
Download (HTTP): http://sqlite.org/2017/sqlite-doc-3190300.zip
Download MD5 sum: e33ee181a52f5e944b6c0e3c3fd44069
Download size: 5.4 MB
libedit and UnZip-6.0 (required to unzip the documentation)
User Notes: http://wiki.linuxfromscratch.org/blfs/wiki/sqlite
If you downloaded the optional documentation, issue the following command to install the documentation into the source tree:
unzip -q ../sqlite-doc-3190300.zip
Install SQLite by running the following commands:
./configure --prefix=/usr --disable-static \ CFLAGS="-g -O2 -DSQLITE_ENABLE_FTS3=1 \ -DSQLITE_ENABLE_COLUMN_METADATA=1 \ -DSQLITE_ENABLE_UNLOCK_NOTIFY=1 \ -DSQLITE_SECURE_DELETE=1 \ -DSQLITE_ENABLE_DBSTAT_VTAB=1" && make
This package does not come with a test suite.
Now, as the
root user:
make install
If you downloaded the optional documentation, issue the following
commands as the
root user to
install it:
install -v -m755 -d /usr/share/doc/sqlite-3.19.3 && cp -v -R sqlite-doc-3190300/* /usr/share/doc/sqlite-3.19.3
--disable-static: This
switch prevents installation of static versions of the libraries.
CFLAGS="-g -O2 -DSQLITE_ENABLE_FTS3=1
-DSQLITE_ENABLE_DBSTAT_VTAB=1": Applications such as
Firefox require secure delete and
enable unlock notify to be turned on. Since firefox-41 the dbstat virtual table is also
required. The only way to do this is to include them in the CFLAGS.
By default, these are set to
"-g -O2"
so we specify that to preserve those settings. You may, of course,
wish to omit the
'-g' if you do not
wish to create debugging information. For further information on
what can be specified see http://www.sqlite.org/compile.html.
Last updated on 2017-06-11 10:46:40 -0500


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Turnitin is a text-matching software that assists students to demonstrate academic integrity in their work. It also allows instructors to easily provide feedback to students and assess their work quickly. Through Feedback Studio, instructors can engage students with targeted feedback. There are two ways to set up a Turnitin assignment, however in order to ensure that the assessment is listed under … Read More
How to: Use the calendar in CanvasEmma Yench and Zaina Indira Nehme
In Canvas, every course and every individual has an associated calendar. You can see all the calendars you have access to by selecting the Calendar link in the global navigation menu. Use the calendar function to keep track of course related events and assessment dates. Features: The Canvas Calendar does not allow instructors to: 528 – Calendar Overview from Canvas LMS on … Read More
How to: Using Canvas CommonsZaina Indira Nehme and Emma Yench
Commons is a learning object repository. You can think of Commons as a digital library that allows Canvas users to find, import and share learning resources with other users around the world. The resources available in Commons are: courses, modules, assignments, quizzes, discussions, pages, documents, videos, audio and images. Yes! When clicking on Commons you will be taken to the … Read More
How to: Get started with Canvas quizzesZaina Indira Nehme
Quizzes in Canvas are a type of assignment designed to assess student understanding and comprehension of course material. Quizzes can be both graded and ungraded. You can create four different types of quizzes in Canvas. These are: The table below compares the types of questions available in Canvas and Blackboard. To road-test the question types you can use in a … Read More
How to: Get Started with Canvas – 5 First StepsCathy Leahy and Emma Yench
Canvas is a cloud-based Learning Management System (LMS). Developed by the US-based company Instructure in 2008, it is now used by more than 2000 schools and institutions. Preview student submissions and provide feedback in the same frame Incorporate multiple content and activity types into a single simple learning pathway Integrate external tools for use within the Canvas space Students can create and … Read More
How to: Transfer content from Blackboard to Canvas – what we know so farEmma Yench, Cathy Leahy and Andrea McLagan
Any one Blackboard or Canvas site may include many different types of content. Some content types can be imported directly from Blackboard to Canvas via export/import with no functional change. Other content types require some management and modification, and still others are not recognised or handled in the same way in Canvas as they are in Blackboard, and need to be … Read More
How to: Structure your content in CanvasCathy Leahy and Emma Yench
In Canvas, content can be organised using files, pages or modules, or a combination of these. Features: Structure: an overview from the University of Washington (Open Canvas Module) More help with Files [Canvas Community resources] How do I create a page? More help with Pages [Canvas Community resources] How do I create a module? More help with Modules [Canvas community documentation] How do … Read More
How to: Set notification preferences in CanvasCathy Leahy and Emma Yench
In Canvas you can control how and when the system notifies you about different activities that are happening in your courses. Default notification come by email, but you can change that to include SMS or a number of other web services. Features: However it differs in that: How do I set my Canvas notification preferences? If you have any examples … Read More
How to: Canvas AnnouncementsCathy Leahy and Emma Yench
A Canvas announcement is a function that allows instructors to communicate with students at a course or group level, to notify them of new content, approaching deadlines and other important course information. Canvas announcements also offer the functionality of student reply to course posts, as well as post and reply to their group posts. However it differs in that: How do … Read More
How to: Canvas AssignmentsCathy Leahy and Emma Yench
A Canvas assignment can be any graded item; papers, quizzes, or even an in-class presentation. It can be anything you wish to record for a student. Create Assignment Groups to categorise work or tasks such as attendance, discussions, papers, quizzes, etc. All groups can be used to create a weighted total for the final grade. Customise submission types from students (you … Read More


text: RT Video/DVD DB /z-wcorg/ DS http://worldcat.org ID 55507384 LA English or dubbed French dialogue, French subtitles; closed-captioned. T1 13 going on 30 A1 Matthews, Gina., Arnold, Susan., Roth, Donna Arkoff., Goldsmith, Josh,, Yuspa, Cathy,, Winick, Gary,, Garner, Jennifer,, Ruffalo, Mark., Greer, Judy,, Serkis, Andy., Baker, Kathy,, Burgess, Don,, Littenberg, Susan., Shapiro, Theodore,, DeSanto, Susie., Stover, Garreth., Revolution Studios., Columbia TriStar Home Entertainment (Firm), PB Columbia TriStar Home Entertainment PP Culver City, Calif. YR 2004 SN 1404936971 9781404936973 AB Jenna makes a wish on her 13th birthday to be 30 and grown up. When she wakes up the next day she finds herself, miraculously, just weeks away from her 30th birthday. The new, older Jenna is a successful magazine editor with friends in high places and a lion's share of potential suitors. The problem is that her mind hasn't matured with her body and Jenna finds it a little more terrifying than cool to be living on her own.


text:
A premier U.S. orchestra, the NSO performs approximately 150 concerts each year of classical, new works, pops, and special events, including nationally televised concerts on the lawn of the U.S. Capitol and numerous education and community engagement events.
One of the leading opera companies in the United States, WNO focuses on bold productions of classic operas, fascinating contemporary perspectives, and the best in American artistry.
Under the artistic direction of George Balanchine's most admired muse, the Kennedy Center's own ballet company encompasses an ever-growing repertoire of beloved ballets including more than 65 works choreographed by George Balanchine, Maurice Béjart, and Jerome Robbins.
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The John F. Kennedy Center for the Performing Arts
2700 F Street, NW Washington, DC 20566
Building opens daily at 10 a.m.
Tickets & Information: (202) 467-4600
Toll-Free: (800) 444-1324
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|Please note: This article is about the ronin archer. For other uses of the term, please see Kesu (disambiguation).
Kesu was a ronin archer of the Flesh Dragons juzimai, led by Kitsure. The bandit gang terrified the village of Mimura since 1121. All the members bore tattoos covering their bodies, riding Otaku Steeds with Unicorn Clan markings on the saddles. The other members of the gang were Reju and Jimitsu. [1]
- ↑ Mimura, p. 43
|This Ronin related article is a stub. That means that it has been started, but is incomplete. You can help by adding to the information here.


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Hotel Star Palace 42
Call us 1800-300-2400-1 (Toll Free) and Get additional Discount upto 50% for this Hotel.
You are getting lowest possible rate for this hotel
- About Hotel
- Reviews
About Hotel Star Palace 42
A round-the-clock front desk facility is available at Hotel Star Palace 42 in Chandigarh. As a value added service, guests are offered 24-hour room service during their stay. Sukhna Lake is approximately 9 km and Chandigarh Local Bus Stand is 5 km from this property. This property provides 7 rooms on 2 floors which are equipped with amenities such as a temperature control, heater, make-up mirror, ensuite bathroom with hot and cold water supply, television, bottled drinking water and a wardrobe.
No of floors: 2 | No of rooms: 7
Checkin Time: 1200 pm
Checkout Time: 1200 pm


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Science Teacher Joshua Woodard 9th grade Honors Integrated Science class at Berea Community High School is designing a project to launch experiments to near space (approximately 120,000 feet) using a high altitude weather balloon. Our 9th grade class is planning the mission, constructing the payload and launch system, running the on-board experiments, and even using the project to learn about force and motion.
Berea is a wonderful community that bridges Appalachia and the Bluegrass. We are a high-needs district with about 65% students receiving free or reduced price lunch. The scale of the project is something the students simply do not see and Continue reading BCHS Science Class Mission to Near Space


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Just as the Vatican newspaper has forgiven John Lennon for his "more popular than Jesus" crack…
The Franciscan Friars of the Atonement at Graymoor are beginning an Advent Vespers series on Sunday called "Giving Peace a Chance: Anticipating the Year of Reconciliation."
All we are sayyying is…
Here's the line-up:
Nov. 30, Rev. Peter Sabune, Episcopal priest, chaplain at Sing Sing, and founder of Forgiveness and Reconciliation Project in Rwanda.
Dec. 7, the Rev. Elias Mallon, a Graymoor Friar and on the staff of Franciscans International at the U.N.
Dec. 14, Doug Hostetter of the Mennonite Central Commmittee.
Dec. 21, Sister Margaret Holden of the Canticle Ministry in NYC, which assists families and individuals coping with HIV/AIDS.
Each program will begin at 4 p.m.


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On the ground in Chicago's West Loop with chef Stephanie Izard
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Just around the corner from Little Goat is the West Loop location of popular donut shop Glazed & Infused. Chef Scott Harris keeps his cases stocked with fresh donuts all day, turning out old-fashioned raised and cake varieties, along with funky inventions like the Pilsen, crowned with mango-pineapple glaze and Mexican Tajín seasoning. Izard will often pick up a few dozen on the way to work to keep her team smiling. Glazed & Infused: 813 W Fulton Market, Chicago; 312-226-5556; goglazed.com


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Join us on an exclusive trip to the western and southern part of Iceland and explore the historical Borgarfjörður, the heart of the Icelandic Sagas and home of magnificent beauty´s of nature and Langjökull Glacier with it´s man made Ice cave. Golden Circle with all it´s glory where Gullfoss waterfall, Geysir and Thingvellir national park are a highlight.
The day starts with picup from your hotel and we head from there on to road nr 1 towards Borgarfjörður. After about an hours drive we will reach the first stop of our expedition at Deildartunguhver hotspring wich is the most powerful hotspring in Europe. From Deildartunguhver we will continue to a waterfall calledHraunfossar or "Lava Waterfalls". After enjoying the magical waterfalls we will drive further inland to Húsafell where we will stop for lunch break and relax before continuing on to the highlands towardsLangjökull glacier, the second largest glacier in Iceland (953 m²) after Vatnajökull glacier. Once we have enjoyed the magnificent view from Langjökull we will drive a mountain road called Kaldidalur or "The Cold Valley" towards our last stop of the day at Þingvellir national park, one of the most beautiful places in Iceland. This is your dream Iceland super jeep tour.
Tour Highligts:
See more details on Langjokull here.
Free hotel pick up in Reykjavík greater area
Tour: BorgarfjörðurMinimum 2 passengers, Saturdays minimum 4 passengersDuration: Approx. 10-11 hoursPick-up from hotel included (Reykjavik capital area)Departure time: 9:00 or by agreementBring warm clothes and good shoes.
(We reserve the right to cancel the tour at any time depending on the weather or other conditions)
Everything is now up to date for you to reserve your dream tour around Iceland. The Northern Lights are in season and the majestic winter is closing in giving you vast variety of exciting tours and extremely beutiful nature to observe. Book your tour here.


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The 2014 Formula 1 Etihad Airways Abu Dhabi Grand Prix will take place on 21st, 22nd and 23rd November at Yas Marina Circuit. The Abu Dhabi circuit has established itself as one of the most spectacular on the F1® calendar and it's the venue for the only twilight race in the programme, meaning that fans can experience the magic of both a day and night race in this marina track setting. It has also become one of the Middle East's premier social and sporting events. Elegant Resorts has access to ticket packages that must be booked by 31st May 2014, that include:• Either a two or three day ticket in your choice of stand • Meet and assist upon arrival at Dubai/ Abu Dhabi International Airport • Return transfers: Dubai/ Abu Dhabi Airport – Dubai/ Abu Dhabi hotel – Dubai/ Abu Dhabi Airport • Return transfers (from selected hotels) to the Abu Dhabi Grand Prix circuit. (Private vehicle transfers can be arranged on request at an additional cost)
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He Asked, They Told
With Dont Ask, Dont Tell officially over, many people are discovering that the old stereotypes related to homosexuality simply dont pass muster. Nowhere is that sentiment clearer than in Scott Pasfields Gay in America, a book chronicling the cross-country journey the photographer took to interview gay men from all walks of life. Courtesy of Books & Books, Pasfield will discuss his project at Design Within Reach Tuesday at 7 p.m. From all 50 states, the 140 subjects represent every income level as well as a range of religions, races, and professions. By documenting these men through stunning portraits and personal essays, Pasfield has made a striking statement about the diversity of the male gay community. Their stories are at various points tragic and joyful, detailing the risks and rewards of accepting themselves and fighting for true equality.
Tue., Nov. 1, 7 p.m., 2011
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Anti-Gravity is an item added to The Binding of Isaac: Rebirth. It is a single tear surrounded by blue "electrons".
Isaac is tinted blue and a symbol of electrons is shown on his forehead.
If the firing key is held, Isaac's tears will float on the place they were created instead of being shot. They will be fired in the same direction they were originally fired after a few seconds or the key is released.
Increase Tears by 0.32.
- The Parasite and Cricket's Body - Split tears will travel a very short distance before landing (If the original tears were split before released).
- The Ludovico Technique, Dr. Fetus, Epic Fetus, Cursed Eye, Technology, Monstro's Lung and Mom's Knife - Completely override Anti-gravity.
- Mom's Wig - Poor synergy. Spiders can only be spawned when the firing key is held, which means not releasing tears.
- A Lump of Coal - Poor synergy. When tears are floating stationary, they do not gain any benefit from Lump of Coal.
- Brimstone - Creates a red sphere when Brimstone is released. The sphere grows larger until it's about the size of Isaac's head, then shrink and fires the Brimstone beam in the direction Isaac initially shot it. During this period the sphere can damage enemies using the same damage and rate of Brimstone. After released, Isaac can instantly start charging another Brimstone again.
- Monstro's Lung- Fire rate is increased without any effects to the tears, essentially taking less time to charge Monstro's Lung.
- Strange Attractor - Floating tears can still pull enemies toward them. This can sometimes prove detrimental, as it leaves a trail of magnetic tears that pull enemies towards Isaac.
- Brimstone and Strange Attractor - Any enemies near the sphere as it grows will be sucked into and take large amounts of damage.
- My Reflection - While holding the arrow keys, floating tears will follow Isaac and hover over him until the arrows keys are released.
- It functions similarly to the Bubbler/Bubbline weapon from Cave Story, albeit initially lacking the ability to block projectiles without Lost Contact and not being able to follow the player around.
- Isaac's appearance bears a strong resemblance to Dr. Manhattan of the Watchmen.


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If an item you ordered from TextbookRush does not meet your expectations due to an error on our part, simply fill out a return request and then return it by mail within 30 days of ordering it for a full refund of item cost.
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Description: A handful of kite hobbyists scattered around the world find each other online and collaborate on the most radical improvement in kite design in decades. A midwestern professor of Middle Eastern history starts a blog after 9/11 that becomes essential reading for journalists covering the Iraq war. Activists use the Internet and e-mail to bring offensive comments made by Trent Lott and Don Imus to a wide public and hound them from their positions. A few people find that a world-class online encyclopedia created entirely by volunteers and open for editing by anyone, a wiki, is not an impractical idea. Jihadi groups trade inspiration and instruction and showcase terrorist atrocities to the world, entirely online. A wide group of unrelated people swarms to a Web site about the theft of a cell phone and ultimately goads the New York City police to take action, leading to the culprit's arrest. With accelerating velocity, our age's new technologies of social networking are evolving, and evolving us, into new groups doing new things in new ways, and old and new groups alike doing the old things better and more easily. You don't have to have a MySpace page to know that the times they are a changin'. Hierarchical structures that exist to manage the work of groups are seeing their raisons d'tre swiftly eroded by the rising technological tide. Business models are being destroyed, transformed, born at dizzying speeds, and the larger social impact is profound. One of the culture's wisest observers of the transformational power of the new forms of tech-enabled social interaction is Clay Shirky, and Here Comes Everybody is his marvelous reckoning with the ramifications of all this on what we do and who we are. Like Lawrence Lessig on the effect of new technology on regimes of cultural creation, Shirky's assessment of the impact of new technology on the nature and use of groups is marvelously broad minded, lucid, and penetrating; it integrates the views of a number of other thinkers across a broad range of disciplines with his own pioneering work to provide a holistic framework for understanding the opportunities and the threats to the existing order that these new, spontaneous networks of social interaction represent. Wikinomics, yes, but also wikigovernment, wikiculture, wikievery imaginable interest group, including the far from savory. A revolution in social organization has commenced, and Clay Shirky is its brilliant chronicler.
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Hey IGN peeps! This isn't a blog post so much as it is a conversation starter. I read 1up's Jeremy Parish's article about the first Parasite Eve game for the original PlayStation and I remember trying the game but not understanding it and giving up. I felt that the game was above what I could understand. A few months ago, I wrote about how I see the Sega Saturn as a console with an aura of mystery and inaccessibility to me. Another article I wrote was about my puzzlement of how gamers played PC games due to the cost of a computer. All of this made me realize that I seem to have had a class based idea of video games. Some games were for poor people (Sega Genesis) and some were for rich people (SNK NeoGeo AES). Games work the same way, with some being for everyone (Spyro the Dragon) and some being for a select few (SaGa Frontier). My question is do any of you feel this way? Do you remember thinking that some games were just too much for you? Do you have a hierarchy like perception of games in some way, either before or now? Comment and let me know. A Thumbs Up is also always nice.
Question: Gaming HierarchySeptember 2, 2011 by Colorwind
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text: needler a needler height 6 ft. weight 150 lbs. weapons arms It appears humanoid, but its arms and legs are replaced with very sharp blades which it uses to walk around, as well as to attack. These blades are grafted onto the severed wrists and ankles of the creature. However, its legs are double-jointed. It seems as though its head had been removed. However, its sharp-mawed mouth is located between its legs. Retrieved from "http://sifsbestiary.wikia.com/wiki/Needler?oldid=9442" Ad blocker interference detected! Wikia is a free-to-use site that makes money from advertising. We have a modified experience for viewers using ad blockers Wikia is not accessible if you've made further modifications. Remove the custom ad blocker rule(s) and the page will load as expected. Categories: Arachnids Medium Carnivore Ground Video game Add category Cancel Save


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Halkett Pub and Eating House
Halkett Place, St. Helier, Jersey, JE2 4WG +44 8439597856
Comfortable dining experience and a great menu to suit everybody. Good attentive staff
Angela Smith
14 februari 2017
från Jersey
Halkett Pub and Eating House in Jersey's St Helier serves up wholesome British classics alongside award-winning ale. Live entertainment comes to Halkett on Thursday, Friday and Saturday, on which nights the pub is open until late.
The 100% Jersey-beef chargrilled burger is joined on the Halkett menu by locally-sourced mussels with French fries, crusty bread and Jersey butter, and a fragrant Thai red curry. Irresistible Sticky toffee pudding or Jersey ice creams with toasted hazel nuts and chocolate sauce can be enjoyed with a range of teas and infusions, or a frothy double cappuccino.
Halkett restaurant brings together traditional pub furnishings with colourful modern artwork and lighting in its quirky interior. Bar snacks such as the tasty pork pie can be enjoyed with a locally-brewed Liberation ale or one of a comprehensive list of wines.
Free Wi-Fi is available in Halkett Pub and Eating House, which sits in Halkett Place in Jersey.
Halkett Pub and Eating House
Halkett Place, St. Helier, Jersey, JE2 4WG
Se alla restauranger i Jersey
Se alla restauranger i St Helier
Kundbetyg för Halkett Pub and Eating House
- Mat
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- Plats
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((((( 20 juli 2017 av Lauren från St Helier
Staff very attentive. Excellent service and great food.
(**** 28 mars 2017 av Nikkie Thompson från Jersey Marine
Service was shocking food was awfu no more to say
((((( 14 februari 2017 av Angela Smith från Jersey
Comfortable dining experience and a great menu to suit everybody. Good attentive staff
((((( 24 januari 2017 av Harry Read från St Helier
We went early for a pre theatre meal and so the restaurant was empty. We were immediately seated and a wine order taken and menus distributed. There was plenty of choice, I chose the steak and mushroom pie and my two colleagues chose the ribs. My pie was excellent the meat was tender and the gravy was rich and tasty, the two girls ribs spread over the end of the plates and were superb, falling off the bone and with a spicy flavour on the skin.
Our only problem was that we had ordered a large portion of chicken wings to share as a starter but they arrived with the main course, a misunderstanding with the waiter, that said they were good with plenty of meat on the bone.
(**** 5 januari 2017 av Katie Hubbard från Jersey
It was very disappointing as it took an hour for our order to come for a lunchtime booking in spite of chasing it twice and making it clear that we needed to be back to work which I don't think would be unusual for lunchtime bookings. It was supposed to be a nice final get together before our daughter went back to the UK and ended up rushed and stressed. I had 5 minutes to eat as much of my curry as possible before my husband and I needed to leave to return to work. Better communication and organisation in the kitchen is definitely needed, the menu is nice but far from complicated and it shouldn't take 1 hour to produce 6 main courses.
((((( 23 december 2016 av Carol Le viellez från Jersey
Booked on line, which was very easy. Food and staff were excellent
((((( 14 december 2016 av Mike Welsford från Plymouth
Every thing you would expect from a well run pub.
((((* 11 december 2016 av Caz Omalley från St Saviour, Jersey
Easy to book online, nice seating, lovely staff and a good meal, what else is there to say!
((((( 21 oktober 2016 av Theresa Banks från Jersey
The service was very good & the food was lovely, staff very friendly
((((( 30 augusti 2016 av Marie Baket från St helier
Great food , great staff
Tyvärr så kan du inte boka Halkett Pub and Eating House online via vår hemsida
Erbjudanden direkt till din inkorg!
Hör om våra topperbjudanden först, och boka de bästa borden.
Du kommer snart att få tillgång till en massa bra erbjudanden
Restauranger i närheten
72m 92 recensionerThe Bar & Canteen
The Bar & Canteen
389m 93 recensionerThe Square Restaurant
The Square Restaurant
403m 13 recensionerMerchant House Brasserie
Merchant House Brasserie
422m 29 recensionerBella Italia - Jersey
Bella Italia - Jersey


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Can Anyone help me to write a momentum source udf ?
I have a fan in the room, i want to simulate this problem but i think in need to define source terms. So i want to write an udf, i am looking for udf manual and examples but i am in a hurry so i need your help. I do not know anything about udf or programming actually so, for example
Can i write udf like this ? Can this solve my problem ? Lets say i can write but how ?
|All times are GMT -4. The time now is 23:59.


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An incredible experience. Lynn is the star of the show! But, right behind her are the other characters that make up this magical accommodation. The main house and 2 other houses have unique and select rooms that will be forever in my memory of travel. Just as you might have read Lynn and her friends will pop their heads into your room or join you for breakfast, dinner or lunch. The service is commendable, the dinners elegantly served and delicious. Four of us traveled together and were fortunate to have the rooms in the main manor called Betty and Jock. You might think this stay to be expensive but, we chose to look at our price per night as a donation to care for the almost extinct Rothschild Giraffe. Accommodation of this standard and donation to the cause in my opinion is a reasonable price. Our experience was in low season of safari travel. This travel period will give you the best time to enjoy Lynn and her friends. Take a moment away from everything and enjoy the beauty of the gentle giants. You too will have an unforgettable experience!
- Also Known As:
- Giraffe Manor Hotel Nairobi


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«The nights are starting to get cold again,» I thought as I lay awake in bed.
The room looked like a tornado had hit it. Clothes, books, drawings, and who-knows-what-else were stacked over almost every possible inch - leaving just a narrow, treacherous path to the bed.
The bed itself was no better. It was turned at a funny angle with the foot of the bed facing the large, picture windows. There was no doubt about it, my housekeeping is not what it used to be.
I stared out at the moon as it peeked up over the run-down buildings, and I felt the cold as it leaked in around the drafty, old windows. It chilled my cheeks and nose.
The dim light glinted off of a small object at the foot of the bed and I gave it a little shove from under the covers. It toppled to the floor and quiet, tinny music crept out from under the bed. I closed my eyes and listened. The batteries were weak. "Mary had a little lamb, little lamb…" I smiled.
A hot arm wrapped itself around my chest and Shadow started to growl in her sleep. I wondered if she was dreaming about running with the pack or chasing a rabbit. It sounded like one of her happy growls.
Shadow put her teeth to my skin and gave me a little nip in her sleep. I jumped only a little.
"Careful with the fangs, sweety," I whispered to her and she released me, the bite becoming a series of soft licks.
I stared some more at the moon and savored the quiet from the nursery. I knew that Shadow would leave in a bit when the moon's pull got too strong. She'd run and scrap with the pack for hours, but for the moment she belonged here.
Living with a werewolf turned out to be easier than anyone ever expected. The elders had really given us very little grief when I told them I intended to marry Shadow. In fact, they just smiled.
Perhaps they were happy for her, happy that she had found love. Perhaps they were surprised by my bravery or foolishness, but after attacking Jack with my magick, neither of those should have been in doubt. Perhaps they figured that I would just leave on my own when I realized how hard it is to keep what I was taking.
I didn't find it that hard at all. Sure, Shadow gets pretty moody when the moon is full, and the cubs can be a handful, but that's to be expected.
The cubs are really great. We picked out Kyle and Samantha as names, but everyone calls them DarkFang and Trixi.
The little nipper, Fang, really takes after his mom. He loves to roughhouse with his Uncle Jack and the rest of the pack. Trix is a real sweety and she loves her brother dearly. I'd like to say that she takes after me (the refrigerator is covered with artwork in crayon), but I can see a lot of both of us in both of them. Trix has Jack and Teacher of Cubs wrapped around her little fingers and I swear that Fang can tell when I'm lying.
Will they someday learn to do magick? Will they sprout fur and grow claws? I don't know. They do love to howl at the moon with their uncles. Actually, Trix loves to howl at the moon. Fang likes to howl at anything.
My family turned out to be more trouble than hers. Mom was quite pissed when she found out I got married. She wouldn't talk to me for a month until it finally drove her nuts enough to call. I could see that both my folks were pretty uncomfortable with Shadow and not the least bit pleased with how young she is, but they do love being grandparents.
They won't come over to the house to visit (the neighborhood makes them jumpy), but they make me bring the kids over all the time. They spoil them silly and get them all wired-up on sugar.
Samantha likes to follow her grandma around and talk to her stuffed dog named Kitten. Kyle likes to roughhouse with grandpa even though grandpa will only pretend he's a wolf and not turn into one like his imaginary friend, Jack. God help me if grandpa ever meets Jack.
Rent goes a lot farther in this part of town - which is a good thing since the kids inherited their mom's appetite. I suppose it's not the best place in the world to raise kids, but no one ever messes with my family.
We did have one break-in when the cubs were infants. Fortunately for the burglar, Jack was crashed out on the couch when he snuck in. Apparently, Jack just dropped him back out the window he had crept in without ever waking either of us up.
I suppose Jack's understated way of dealing with things that are not really threats may have made some impact on him. I know I would have given him a lesson he wouldn't have forgotten so quickly, and I don't even want to think about what Shadow would have done to him if she had woken up.
Jack turned out to be a much more decent guy than I ever would have guessed. He's not as rough with Shadow anymore, even when she's being stubborn. Violence between the Garou is something that I don't like, but you do learn to accept it. They have to let it vent some and they control it much better than I would have guessed. A broken arm to them is like a spanking to a child.
Needless to say, discipline in our family works a little differently from how it does in a pack.
Shadow's life is a dangerous one, so we live each day like it might be her last.
She makes a good mom though, despite the fact that she tells a different version of "The Three Little Pigs" and "Little Red Riding Hood" than the ones I heard when I was growing up.


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Genital herpes is a sexually transmitted disease caused by the herpes simplex virus type 2 (HSV-2). While infection is often a result of sexual intercourse, it can also be passed from one person to the next by skin-to-skin contact. Regardless of how the virus is transmitted, exposure can cause a male to suffer from certain symptoms.
For some men, it is possible to experience no symptoms of genital herpes at all. It may take years for them to suffer symptoms of the condition.
For others, an infection may start out with some level of itching in the area of exposure, such as the penis, testicles, anus or even thighs, sometimes in as little as a few weeks after contracting the virus.
It is also possible for a man to experience a certain amount of pain in these same areas. This pain may be subtle-to-pronounced in nature and may manifest in as little as a few weeks after contracting the virus.
Many times, a case of genital herpes causes a male to experience blisters along the area of exposure.
As the outbreak persists, some men develop small sores or ulcerations along the same area of the body.
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- Male Genital Grooming Tips


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But no, the purpose of existence isn't just reproduction. It just happens to be the purpose of the bodies we inhabit. The purpose of the mind is far more intricate, individual and undecipherable than that.
The purpose of existence as a whole? I have no idea. Not even a starting-point. I like to think existence is just there for the fun of it.