text:
|Publication number
|Publication type
|Application number
|Publication date
|Aug 24, 1999
|Filing date
|Nov 17, 1997
|Priority date
|Dec 5, 1996
|Fee status
|Publication number
|Christian Monereau, Dominique Rouge, Jean-Claude Calviac
|Original Assignee
|L'air Liquide, Societe Anonyme Pour L'etude Et L'explooitation Des Procedes Georges Claude
|Export Citation
|BiBTeX, EndNote, RefMan
|Patent Citations (19), Referenced by (3), Classifications (17), Legal Events (6)
|External Links: USPTO, USPTO Assignment, Espacenet
This application corresponds to French application 96 14955 of Dec. 5, 1996, the disclosure of which is incorporated herein by reference.
The present invention relates to a process for the treatment of a gaseous mixture by adsorption with pressure variation, of the type comprising, for an adsorber, a succession of stages which define, in a successive and cyclic manner, an adsorption phase, a regeneration phase of the adsorbent comprising a step of depressurization, and a phase of pressure increase, the passage from one phase to the other comprising switching of at least one valve.
The invention is applicable in particular to the production of oxygen from atmospheric air.
The pressures in question are absolute pressures, and the flow rates are molar flow rates.
The invention has for its object to reduce the expenditure of specific energy, as well as the unit cost of production, by a better handling of the phenomena of moving the adsorbent beds and the kinetic phenomena.
To this end, the invention has for its object a process of the mentioned type, in which at least one switching of the valve is carried out according to a progressive programmed slope to control a first cocurrent decompression stage of the adsorber with transfer of gas toward a unit of the installation at lower pressure.
According to one aspect of the invention, said valve switching is carried out according to a programmed progressive slope to transfer gas toward another adsorber in pressure increase phase, toward an auxiliary storage, or toward another adsorber for its countercurrent elution adjacent the low pressure of the cycle.
An example of operation of the invention will now be described with respect to the accompanying drawing, in which:
FIG. 1 shows schematically, by way of example, an installation for the production of oxygen according to the invention;
FIG. 2 is a diagram which illustrates an example of operating cycle with this installation; and
FIG. 3 is a diagram which illustrates on the one hand two different modes of operation of the balancing valve, and on the other hand corresponding variations of the flow rate which pass through it in the balancing phase.
The installation of the VSA type shown in FIG. 1 is typically adapted to produce air enriched in oxygen, or impure oxygen (called "oxygen" for the sake of simplicity) with a content comprised preferably between about 90 and 95%, from atmospheric air.
In the illustrated embodiment, the installation comprises essentially two adsorbers 1A and 1B, a compressor 2, a vacuum pump 3 and an assembly of conduits and valves, as well as control and regulation means (not shown), suitable to practice the cycle illustrated in FIG. 2.
There is schematically shown in FIG. 1:
a supply conduit 4 for atmospheric air which leaves the output of the compressor 2 and which is divided into two branches 4A and 4B provided with respectively supply valves 5A, 5B and connected respectively to the lower input 6A, 6B of the adsorbers;
a purge/elution conduit 7 which is divided into two branches 7A, 7B provided with purge/elution valves 8A, 8B and leaving respectively the inputs 6A, 6B of the adsorbers;
a production conduit 9 which is divided into two branches 9A, 9B provided with production valves 10A, 10B and leaving respectively the upper outlets 11A, 11B of the adsorbers; and
a balancing/elution conduit 12 which directly interconnects the outputs 11A and 11B and which is provided with a balancing/elution valve 13.
The intake of the compressor 2 and the output of the vacuum pump 3 are in communication with the surrounding atmosphere. The adsorbers 1A and 1B each contain at least one bed of an adsorbent adapted to adsorb selectively nitrogen from air, which is in this example a molecular sieve of the type CaA.
By means of the installation thus described, the adsorption cycle with pressure variation is practiced with vacuum (Vacuum Swing Adsorption or VSA) illustrated in FIG. 2.
In FIG. 2, in which the time t is given on the abscissa and the absolute pressure P on the ordinate, the lines indicated by arrows indicate the movements and destinations of the gaseous currents relative to an adsorber.
In the example in question, the high pressure PM of the cycle is slightly greater than atmospheric pressure, typically between 1.1 and 1.4�105 Pa, for example about 1.3�105 Pa, whilst the low pressure Pm of the cycle is substantially less than atmospheric pressure, typically between 0.3 and 0.5�105 Pa, for example about 0.4�105 Pa.
The cycle will be described below for one adsorber, namely adsorber 1A. The other adsorber 1B follows an identical cycle but offset timewise by a half-period T/2.
The cycle is constituted of the following successive steps:
(a) Adsorption phase (substantially isobaric):
(a1) From t=0 to t1, a first cocurrent adsorption step, in which the air to be treated is introduced via conduit 4 to the inlet of the adsorber near the pressure PM and circulates cocurrent through the latter. The production oxygen is withdrawn at the output of the adsorber and sent to the production conduit 9.
(a2) From t1 to t2, a second cocurrent adsorption step, which differs from the preceding only by the fact that a fraction of the produced oxygen is withdrawn at the outlet of the adsorber and is sent countercurrent into the other adsorber in the purge/elution stage (b3) described further on.
(b) Adsorbent regeneration chase:
(b1) From t2 to t3, a first cocurrent decompression step with pressure balancing with the other adsorber in the first countercurrent recompression phase (c1) described later. In the course of this step, the pressure of the adsorber falls from PM to an intermediate value PE.
(b2) From t3 to t4, a countercurrent purge step under vacuum. In the course of this step, the inlet of the adsorber is connected to the vacuum pump, which brings the pressure to the low pressure of the cycle Pm.
(b3) From t4 to t5, a purge/elution phase adjacent the low pressure PM. In the course of this step, the inlet of the adsorber is again connected to the vacuum pump, and, simultaneously, its output is connected to that of the other adsorber, which is undergoing the second adsorption phase (a2).
(c) Recompression Phase:
(c1) From t5 to t6, a first countercurrent recompression step by pressure balancing with the other adsorber in the course of first cocurrent decompression step (b1) . At the time t6, the pressure has risen to the intermediate PE.
(c2) From t6 to T, a final cocurrent recompression step by means of air from the compressor. At time T, the pressure has returned to the vicinity of the value PM, and the cycle begins again.
By way of numerical example, the durations of the steps described above are successively 4 s, 10 s, 7 s, 20 s, 10 s, 7 s and 16 s.
The balancing/elution valve 13 is a valve with its opening programmed according to a predetermined slope.
Thus (FIG. 3), the control of the onset of the balancing step (b1), from time t2, takes place not by substantially instantaneously opening the valve 13 to its nominal opening, but by following a progressive opening slope which extends over a substantial fraction of the interval from times t2-t3 corresponding to this step.
There is shown in FIG. 3 two different slopes which have been tested on an industrial scale:
in broken line, a slope R1 which produces an opening increasing linearly from 0 to 73% of the nominal value, within 3 s, the opening then remaining equal to 73% to time t3; and
in full line, a much more progressive slope R2 (of lower inclination), which represents an opening increasing linearly from 0 to 81% in 7 s (duration of step t2-t3 in the example in question).
There is also illustrated in FIG. 3 the variation of the instantaneous flow rate D which flows through the valve 13 in each of the two cases mentioned above:
In broken line, the curve D1=f(t) corresponding to the slope R1. This curve has a hyperbolic appearance, with a first half which descends abruptly and a second half, which is longer, which descends less abruptly. In this case, the quantity of gas which passes through the valve 13 during the first half of the interval from times t2-t3 is of the order of 70% of that which passes through the valve during all of this time interval.
In full line, the curve D2=f(t) corresponding to the slope R2. This curve has an elliptical appearance, with a first increasing half, a second half substantially constant and a second decreasing half. About 50% of the quantity of gas transferred during the time interval t2-t3 takes place in the course of the first half of this interval.
The technico-economic computations carried out in the two cases above, with a hypothesis of oxygen production of 93% purity, show that the productivity of the installation (quantity of oxygen produced per unit time and per unit volume of adsorbent) is greater in the case of the slope R2, and that, in the same case, the specific energy expenditure as well as the unit cost of the oxygen product are reduced.
Thus, a greater progressivity of the opening slope of the balancing/elution valve 13 improves the performance of the installation. The reduction in specific cost of the oxygen, relative to the use of a valve 13 which abruptly opens all the way, is of the order of 5%.
It is to be noted that, in the installation of FIG. 1, the valve 13 also serves as the elution valve. Accordingly, the purge/elution step can also be controlled with a progressive opening slope, identical to R2 or different. As a modification of the cycle of FIG. 2, the elution (3) can be carried out via the valve 13, with the gas from the first countercurrent decompression step via a storage chamber (not shown), and the first recompression step at least in part by the production gas.
|Cited Patent
|Filing date
|Publication date
|Aug 9, 1967
|Mar 4, 1969
|Union Carbide Corp
|Selective adsorption process
|Dec 30, 1968
|Feb 23, 1971
|Union Carbide Corp
|Selective adsorption process
|Jan 4, 1971
|Jan 25, 1972
|Union Carbide Corp
|Selective adsorption gas separation process
|Jul 23, 1980
|Feb 16, 1982
|Linde Aktiengesellschaft
|Adsorption process producing chronologically constant amount of a residual gas
|Mar 27, 1981
|Sep 7, 1982
|Boc Limited
|Process for the separation of a gaseous mixture
|Oct 5, 1984
|May 20, 1986
|Union Carbide Corporation
|Pressure swing adsorption process
|Sep 1, 1987
|Aug 2, 1988
|Union Carbide Corporation
|Pressure swing adsorption control method and apparatus
|Feb 1, 1989
|May 15, 1990
|Kuraray Chemical Co., Ltd.
|Process for separating nitrogen gas by pressure swing adsorption system
|Jul 5, 1989
|Nov 13, 1990
|L'air Liquide, Societe Anonyme Pour L'etude Et L'exploitation Des Procedes Georges Claude
|Process for treating a gaseous mixture by adsorption
|Sep 28, 1989
|Jan 1, 1991
|L'air Liquide, Societe Anonyme Pour L'etude Et L'exploitation Des Procedes
|Process and plant for separating a gaseous mixture by adsorption
|Sep 14, 1988
|May 14, 1991
|Japan Oxygen Co., Ltd.
|Adsorptive separation process
|Sep 27, 1991
|Nov 2, 1993
|The Boc Group, Inc.
|PSA system with product turndown and purity control
|Oct 16, 1992
|Nov 16, 1993
|L'air Liquide, Societe Anonyme Pour L'etude Et L'exploitation Des Procedes Georges Claude
|Process for the production of a gas having a substantial oxygen content
|Dec 16, 1993
|Apr 18, 1995
|Praxair Technology, Inc.
|Tuning of vacuum pressure swing adsorption systems
|Apr 25, 1994
|Dec 12, 1995
|Airsep Corporation
|Capacity control system for pressure swing adsorption apparatus and associated method
|Nov 30, 1994
|May 28, 1996
|The Boc Group, Inc.
|Pressure swing adsorption process
|Jul 12, 1995
|Oct 15, 1996
|Praxair Technology, Inc.
|Optimal pressure swing adsorption refluxing
|Oct 4, 1995
|Aug 12, 1997
|Air Products And Chemicals, Inc.
|Multibed pressure swing adsorption apparatus and method for the operation thereof
|Nov 22, 1995
|Jan 27, 1998
|Praxair Technology, Inc.
|Oxygen recovery pressure swing adsorption process
|Citing Patent
|Filing date
|Publication date
|Dec 18, 1998
|Jul 18, 2000
|L'air Liquide, Societe Anonyme Pour L'etude Et L'exploitation Des Procedes Georges Claude
|Process for gas separation by adsorption with variable production rate
|Dec 21, 2001
|Nov 23, 2004
|L'air Liquide, Societe Anonyme Pour L'etude Et, L'exploitation Des Procedes Georges Claude
|Method for treating a gas by adsorption and corresponding installation
|Dec 21, 2001
|Mar 25, 2004
|Alain Guillard
|Method for treating a gas by adsorption and corresponding installation
|U.S. Classification
|95/98, 95/105, 95/102, 95/101, 95/130
|International Classification
|Cooperative Classification
|European Classification
|Nov 17, 1997
Owner name: L AIR LIQUIDE, SOCIETE ANONYME POUR L ETUDE ET L E
Free format text: ASSIGNMENT OF ASSIGNORS INTEREST;ASSIGNORS:MONEREAU, CHRISTIAN;ROUGE, DOMINIQUE;CALVIAC, JEAN-CLAUDE;REEL/FRAME:008891/0945
Effective date: 19971112
|Jan 17, 2003
|Fee payment
Year of fee payment: 4
|Jan 16, 2007
|Fee payment
Year of fee payment: 8
|Mar 28, 2011
|Maintenance fee reminder mailed
|Aug 24, 2011
|Lapse for failure to pay maintenance fees
|Oct 11, 2011
|Expired due to failure to pay maintenance fee
Effective date: 20110824


text:
Credit Card Center Advertiser Disclosure†
I'm inquiring for a family member who is wondering if it's possible to hold two Chase Slate's at once. Their Chase Platinum turned to a Chase Slate automatically and has $16,000. Now they were actually wanting to apply for the Chase Slate to get the 0% balance transfer with $0 balance transfer fee deal.
Does anyone know if Chase will allow someone to have two Slate's?
Sorry, not possible.
01-31-2013 02:57 PM - edited 01-31-2013 03:07 PM
afbar1114 wrote:
I think it might be possible but they won't get that offer. Most of those offers are for new customers only
Thanks insidious and afbar. Good to know. Looks like they're stuck paying a 3% balance transfer fee with whatever card they choose at this point, because from what I can tell the Chase Slate is the only card offering 0% balance transfer and $0 balance transfer fee. The Citi Simplicity looks like a pretty good offer for them with 18 months @ 0%.
I know from first hand. Apped for slate for the 0% for 15 months they were offering even though I already have a slate. Auto denied and reason was already have a slate and didn't even pull my credit since it was auto denied.
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subset: commoncrawl


text:
Napa Tourism
Visit Napa - Best of Napa
With little to introduce, Napa is America's favourite vineyard county. Vineyards stretching into eternity against the backdrop of the crimson sun, shielded by the Mayacamas Mountain Ranges, Napa need no reason to be a quick escapade. Lush green panoramas, contrasted by the cobalt skies, as you sip of some of the world's most savoury wine, is one experience you can cherish forever.
Famous for its wine, Napa is home to over 400 wineries, making it one of the world's premier viticultural regions. If you love good food and great wine, Napa is got to be on your checklist. With abundant things to do and see, this is a city that will make you want to not leave. Vineyard activities, wine-tasting on a train, spectacular spa services, luxury hot air balloon rides, and some great hikes, Napa is a dream!
Not surprisingly, Napa has more than four million visitors annually. And you will know why, on your visit here.
Napa, a town located in the Napa Valley region of the state of California, is the biggest of the five towns in the region. Napa is known for its wine, wineries, food, spa, sunsets and luxury. Things to do in Napa include: Wine Tours; you can visit its many wine estates and spend a day experiencing pure luxury with chauffeured wine tours paired with great food and some wine tasting sessions; Hot Air Ballooning, fly high up in the air and enjoy the beautiful scenery of lush green farms while sipping on some wine as the pilot guides you though the beautiful valleys; Visit Uptown Theatre to experience live entertainment; Visit barbeque and grill house with your family and friends to enjoy some delicious meat along with some great wine.
Explore the best travel planner for your visit to Napa and create a flawless plan in few simple steps!
Trip plans for Napa
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3 Days 100 Views


text:
Women who believe they may be pregnant can now check online using a new service from the NHS, it has been announced.
The "contraception checker" takes women through a series of questions before providing advice about what they can do to get help and where they can find emergency contraception or family planning information.
The service from NHS Direct, which can deal with queries about missed contraceptive pills and its interaction with other medicines, has been used by 34,700 people so far.
Anne Joshua, Associate Director of Pharmacy at NHS Direct, said sexual health was one of the major public health challenges the country faces today, with unplanned pregnancy the most problematic.
She added: "The contraception checker is ideal for anyone in urgent need of information about what to do if they have had unprotected sex but who also wishes to remain anonymous.
"The user is advised about the next steps to take according to the tried and tested protocols NHS Direct has developed to support telephone calls.
"In some cases, users may be advised to seek professional advice about taking the emergency hormonal contraceptive pill."
Copyright © Press Association 2009
Your comments (terms and conditions apply):
"I think a service for obtaining accurate health and health-related information can only be a good thing. The checker as first line for information and advice I welcome. It will certainly make my role somewhat easier as clients having accessed the information before being seen by a professional would have been better prepared for the two-way consultation approach to reaching and making decisions." - V Henry


text:
Almost surround by water, it's among the most beautiful plazas Cancun offers. You may want to go to The Barnacle Historic State Park on Biscayne Bay or stop by the Coral Castle that is a famous Miami attraction. The beach was declared a particular protection zone for over 25 decades, but the tests that sea turtles should faced in recent decades continue growing. Turtle Beach is a rather common brand, and this particular model is quite powerful. There's a Turtle Beach for the kiddies so that they don't need to navigate the bigger water slides. Green sea turtles are placed close to the coastline. You can swim with dolphins.
The info isn't difficult to locate online so no big thing. Below are some things which you should think about when searching for a gaming headset. Hewlett-Packard's notebook line have great rates and good hardware components. That is why the ideal brand for electronics is Apple. Prices are extremely affordable here as well.
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Top Choices of Turtle Beach Px4
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text: This year my main goal is to lose weight as much as I can. Being a mum of twins is never easy and to top it up with husband who travels way too often , things get even more tough. This is the first day with the Fitbit and I am absolutely excited with this new gadget. It is completely inspiring me, motivating me and challenging me . The guilt of spending for this gadget and it being on my wrist round the clock is my inspiration. Hopefully I will start seeing the results. First half of the day went great. Let's c how the rest of the day goes. Anyone else who uses a Fitbit here? Let's sync .


text:
Blockstream engineers Paul "Rusty" Russell and Dr. Christian Decker completed their initial lightning transaction on Bitcoin's testnet this week. The exam transaction was done regulating a latest chronicle of a Blockstream's lightning antecedent software, lightningd 0.5 and consisted of a digital squeeze from a web-store.
Speaking to Bitcoin Magazine Decker said:
"This is a large miracle for us. It's a initial time we have a channel setup on a genuine blockchain, with genuine latencies and retard rates, and it's a initial multi-hop transaction, where a remuneration for a digital good routes from one node to another by a third node."
Making a Transaction
The rarely expected lightning network is a due second-layer custom to be rolled out on tip of Bitcoin's blockchain. Cleverly utilizing Bitcoin's programmable elements (e.g., multi-signature and timelock) lightning users should be means to make a probably total series of off-chain exchange during low cost, potentially boosting Bitcoin's micropayment-ability and altogether scalability.
Several teams are now operative on opposite implementations of lightning software. Only final week, BitFury, Lightning Labs and ACINQ announced a successful exam of due lightning routing complement Flare, since a Lightning Labs
Read more ... source:
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text:
Android Recipes: A Problem-Solution Approach
Paperback(1st ed.)
Get it by Wednesday, October 25
, Order now and choose Expedited Delivery during checkout.
Same Day delivery in Manhattan. Details
Android continues to be one of the two leading mobile OS and Development platforms driving today's mobile innovations and the apps ecosystem.Android comes off as complex, but offers a variety of organized development kits to those coming into Android with differing programming language skill sets.
Android Recipes: A Problem-Solution Approach guides you step by step through topics using complete and real-world working code examples.
In this book, you quickly get a refresh of the Android app architecture and explore Android-specific APIs.Then, you get down to business and build apps with Googles Android SDK at the command line. You'll learn all aboutusing NetBeans, Eclipse, theApp Inventor tool, and the Scripting Layer for Android tool. You'll alsolearn how toimprove app performance via the Android NDK, and much more.
Instead of abstract descriptions on complex concepts, you find live codeexamples in this book. When you start a new project, you can consider copying and pastingthe code and configuration files from this book, and then modifying them for your own customization needs. This can save you a great deal of work over creating a project from scratch!
What youll learn
- Discover app architecture and various Android-specific APIs
- How to develop the app in the context of command-line/Android SDK, NetBeans/Android SDK, and Eclipse/Android SDK environments
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- How to develop the app using the SL4A tool
- What scripting languages are supported in Android
- How to boost app performance by using the Android NDK
- Howto directly access OpenGL ES 2.0 features
Newcomers to Android as well as more accomplished Android developers.
Product Details
|Publication date:
|Edition description:
|1st ed.
|Product dimensions:
|7.50(w) x 9.20(h) x 1.10(d)
About the Author
Jeff ""JavaJeff"" Friesen is a freelance software developer and educator specializing in Java and now Android technology. In addition to teaching Java at a local college, he's written several books on Java, with Learn Java for Android and Beginning Java SE 6 Platform: From Novice to Professional being his most recent books. Jeff has also written numerous articles for java.net, InformIT.com and JavaWorld.com. Check out his javajeff.mb.ca website to discover these articles, as well as additional material on Java, JavaFX, and other software technologies.
Customer Reviews
Average Review
Most Helpful Customer Reviews
This is book is an excellent addition to the bookshelf of any serious android developer. Android Recipes is primarily geared toward an experienced android developer. However, even a beginning android developer (with a solid understanding of the Java programming language) will find it beneficial. What sets this book apart from most is its clear, concise explanations. I have tested and implemented many of the solutions in this book. After reading Chapter 5: Persisting Data, I was able to implement a content provider of my own in no time. Pros: Clear, concise explanations of complex topics. Code examples available on-line. Cons: None This is the best android book I have read so far, and I definitely recommend it to anyone serious about Android development.
If you are an Android developer, this is book you want on your shelf. Android Recipes gives you examples of working code to solve real world problems. Sure you can find the information on-line, but where else will you find all of this information in single, easy to use source, without spending hours digging through random web pages looking for a working example. While reading the book, I found myself frequently stopping to make notes or sending myself an email so I could try something new at work the next day. I can say that my understanding of what is possible has grown and my apps are better as a result. Like many recipe books, the layout is a problem and solution format. The chapters are logically divided into things like system services, communications and networking, and working with libraries. Each chapter gives a multitude of problems which Android developers face daily. Then, and example is given of how to solve the problem. Best of all, the examples are thorough. Many books gloss over simple things like the layout of a screen. The authors have obviously taken the extra effort to provide a complete example of each solution. So what can you expect to learn? This is a VERY short list of some of the problems which this book helps solve. UI challenges such as manually handling UI rotation and creating pop-up menu actions. Parsing XML and JSON. Receiving SMS messages and capturing notification events. Capturing and playing back audio and video. Using the scripting layer to run shell and python scripts. Persistent data and working with the SQLite database. Integrating 3rd party JARs into your project If you are on the fence about this book, I encourage you to take the plunge and buy it. You will not be disappointed.
I really enjoy to read and meanwhile work with the Android Recipes book because it is very well structured and useful as a reference book. There are many useful recipes which are needed in the daily life of nearly every Android developer. Moreover the reader is also lead to further more specific problems and possibilities he did not know so far. Furthermore this book does not constrain itself and therefore the reader to specific tools but makes a lot of offers with introducing several tools or libraries and their use for specific tasks. Beside that authors spend a whole chapter in describing the basics of the Android platform which are essential to be understood by each Android developer. So what recipes can you find in Android Recipes and how useful are they for the daily life of an Android developer? You will find are a good mix according to different stages of programming. There a recipes for simple standard tasks which you learn when you start Android programming like creating an user interface via xml. You find also tasks which you will probably need after you are finished with playing around and want program more individualized applications like for example customizing the view and the behavior of user interface controls like Lists. Furthermore you find also some surprises in the recipes like a recipe for providing a individual Java Script API which allows a Website to communicate with your Android application through the browser. Another aspect is the structure of the book. For every recipe you find a triple consisting of a short problem description, a short description of the proposed way to solve it and lastly the detailed manuel for implementing the solution. Especially the second part where the problem-solving approach is described in a few sentences allows you to determine very fast if the recipe will help you with your problem. Also the solutions themselves are very structured and in my opinion the highlighted text-boxes where important aspects and sticking points are emphasized are very useful. Also very interesting are the appendix chapters where Android Scripting and the NDK are introduced for further reading and where guidelines are presented which describe aspects of a good app design. Since Android Recipes targets advanced Android developers I really would have appreciated if this guidelines would have got more room than a few pages in the appendix even though they were very good. As a conclusion as supplement to other Android books especially when you often develop with Android and for people who already programmed some basic Android apps and want to go further Android Recipes is a very good buy. Especially for people like me who like to learn with examples. Altogether he book delivers what it promises.


text: Entertainment Tuesday Life Hack: Hairspray is the answer There's so much more you can do with hairspray than to make your hair pretty. March 8, 2016 Get rid of flies: The hairspray will make its wings sticky and no longer bothering you.Strengthening stockings: No more toes poking through or ladders.Clean lipstick stains: Just spray and wait till the stain has dissolved.Flower preserver: Keep the memories, spray the flower to prevent it from crumbling.Static fighter: The water and alcohol in the hairspray calms down the static. Hairspray also removes permanent marker doodles. Watch the video below to see: WebsiteWebsiteWebsite WebsiteWebsiteWebsite WebsiteWebsiteWebsite SHARE AUTHOR Caxton Central


text: New Search 11552 Practice accepting new patients. John P. Loftus, MD (707) 252-4411 x2735 Primary Specialties General Surgery Vascular Surgery Primary Office Address: St. Joseph Health Medical Group 1100 Trancas St. Suite 212A Napa, CA 94558 Phone: (707) 252-4411 x2735 Fax: (707) 251-1345 Hours: Mon - Fri: 9 a.m. - 5 p.m. Secondary Office Address: 16152 Beach Blvd. Suite 173E , Recommend this Physician Request an Update for this Physician Get Directions Education Medical School: Mayo Medical School - 1989 Fellowship: Mayo Clinic Graduate School of Medicine - 1995 Fellowship: Stanford University - 2002 Internship: Mayo Clinic Graduate School of Medicine - 1990 Residency: Mayo Clinic Graduate School of Medicine - 1994 Board Certified in General Surgery Board Certified in Vascular Surgery Certifications Fellow of the American College of Surgeons Areas of Interest Endovascular surgery Minimally invasive surgery


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Mankato State University geometry course
Think about what career is best suited for you, and where you want to study. Request more information now.
Think about what career is best suited for you, and where you want to study. Request more information now.
Think about what career is best suited for you, and where you want to study. Request more information now.
Learn about Mankato State University geometry course, and registering for discussion sections. Which college degrees give you the best chances of finding employment after graduation? Engineering job offers command high salaries due to accelerating technical innovation in manufacturing and heavy industry. Concentrating on Mankato State University geometry course, for example, you may gain an advantage in job recruiting on-campus. Check with the mathematics department for course registration deadlines, and geometry program requirements. Please use the form above to request admissions info for Mankato State University.
While a math degree may not seem like a path to wealth at first glance, many fields are based almost entirely on a math foundation. For instance, both physics as well as engineering make use of algebraic formulas to determine motion and forces on objects, and the stress on materials. In business, financial accounting and stock investing count on the mathematical principle of compound interest over time. Math classes may be refocused toward practical applications, such as numerical analytics of big data online or statistical interpretation of scientific research results. Further, financial engineers or 'quants' may be called upon to prepare math-based reports for financial management, in order to develop high-speed, stock investment algorithms.
Finally, there is a lot of mathematical calculation behind complex decisions such as whether a business should raise money by issuing stock directly to the public as in the case of Google, or seek long-term loan financing? Both decisions involve quantification of risk and substantial probability analysis. A discount rate is used to determine the present value of the expected returns, and if a business anticipates being highly profitable in the short-term, it may be wiser to take out a bank loan, rather than dilute ownership via exanding the number of shares outstanding. Beyond major requirements within the mathematics department, you may consider Saginaw Valley State University structural design as an adjunct to your primary course of study.
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By Nicolo Machiavelli
The Prince by means of Nicolo Machiavelli. world wide literature vintage, between most sensible a hundred literary novels of all time. A needs to learn for everyone, a booklet that might preserve announcing what it has to assert for years.
Read Online or Download The Prince (Classical Books) PDF
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The crash killed at least 43 people on board leaving two others critically injured, out of which 27 were players of the Lokomotiv Yaroslavl team, along with 7 club officials and 2 coaches.
"I'm in shock!!!!!R.I.P ..." read a tweet from Alex Ovechkin, Russian NHL star.
According to officials, Alexander Galimov, Russian player and a crew member survived the crash.
"We were shocked by the news of their death," said Tomas Kral, Czech ice-hockey association chief.
"They were not only excellent players, but also fantastic friends and people. This is how they will be remembered," he added.
OneIndia News


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I made the mistake of staying up way too late last night doing some serious blog stalking. While I love reading all the great adoption stories out there from other families like ours, it was really hard to wake up, will myself out of bed and get to church on time. Or, almost on time.
Our church does a great job of honoring moms and dads on Mother's and Father's Day and I'm blessed to attend the same church as my folks. The congregation today was given the opportunity to share testimonies about our dads during the service and I knew that God was pressing upon my heart to share something about my dad.
We've grown close this past year and I'm so thankful for him and for his spiritual leadership as the patriarch of our family. I really love that guy. And, had I been able to get through saying that about him without blubbering and crying like an idiot, it would've been pretty great to share that with my church family. Oh well… Better luck next time. 😉
And, then there's my Brad. What can I say? I could pretend that he's not near perfect but, truth is – he's just about as close as they come. And he likes me. A lot…. A whole lot more than I deserve to be liked. He's my very best friend and the only person who knows all of my shortcomings, vulnerabilities and failures and loves my anyway. He loves his daughters in a way that I know will make them seek out men like him when it comes time for them to be married.
I can't wait to see him with our son someday.
Psalm 127:3,5
"Children are a gift from the Lord;
they are a reward from him.
How joyful is the man whose quiver is full of them!"


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Michael has an ongoing relationship with many speakers bureaus. As a partner with these bureaus, a client may book Michael through any local bureau... and the investment is exactly the same. Clients never pay more for using bureaus; Michael simply pays them their commission -- making this a brilliant timesaving and energy-saving move for you as the client.
-Michael Scott Karpovich
Michael is thrilled to work with any professional bureau. You may seriously consider contacting one of these hard-working Bureaus:
Phil Frankio of Speakers Guild78 Old King's Highway, P.O. Box 1540Sandwich, MA United States 02563Voice 1-800-343-4530Fax firstname.lastname@example.com
David Pace of Business Speakers Bureau1740 Lockmere Dr. S.E.Grand Rapids, MI 49508Voice email@example.com
Chris Fisher of Fisher Group/Jostens Speakers Bureau P.O. Box 727Danville, CA United States 94526Voice 1-800-541-4660Fax firstname.lastname@example.com
Rob Carsello of SPEAKER RESOURCE CENTER INC20 N WACKER DR STE 756CHICAGO, IL 60606 United StatesPhone: 312-641-6362Fax: 312-416-7970Email: email@example.com
Michael Frank of Speakers UnlimitedP.O. Box 27225Columbus, OH United States 43227Voice 1-614-864-3703Fax firstname.lastname@example.com
Excellence in Presentations 11129 Walmort RoadWilton, CA United States 95693-9748Voice 1-916-687-8486Fax firstname.lastname@example.com
Susie Christie
Holly Zelinsky of National Speaking10186 Bald Eagle TrailWoodbury, MN United States 55129Voice firstname.lastname@example.com
Maureen Brooks of Brooks International763 Santa Fe DriveDenver, CO United States 80204Voice 1-303-825-8700Fax 1-303-825-8701
Chris Reagan of Get Ahead ProductionsP.O. Box 58081 Freeman Hall Road Nottingham, New Hampshire 03290-0580Voice 1-800-943-7747Fax email@example.com
Marsha Broniszewski of Keynote ConsultantsP.O. Box 4182Pittsburgh, PA 15202Voice 1-412-734-2986Fax email@example.com
John McConahy of Imagination Plus34 Terrace RoadPittsburgh, PA 15106-1053Voice 1-412-276-0122Fax firstname.lastname@example.com
Michael McFarlane of Walters International Speakers Bureau P.O. Box 398Glendora, CA United States 91740Voice 1-626-335-8069Fax email@example.com
Susie DeWeese of Speakers Corner15332 Antioch Street #209Pacific Palisades, CA 90272 United StatesVoice 1-310-230-2242Fax firstname.lastname@example.com
Renee Strom of The Speakers BureauP.O. Box 390296Minneapolis, MN United States 55439-0296Voice 1-800-397-2841Fax 1-612-941-1994
To visit our bureau friendly website (with no personal contact information) go to http://bureau.espeakers.com/simp/viewspeaker1608
We actively maintain our calendar with eSPEAKERS so our bureaus may place holds on our calendar even when it may be difficult to get in touch with Michael or our office directly. This virtual calendar is our first and most accurate calendar! All our bureaus are encouraged to work with eSPEAKERS so that we may both be more professional and so that we may both serve the client best!


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Malawi : Monkey Bay .
Malawi is a country found in south-east Africa and is fondly referred to as the warm heart of Africa. The country boasts of having indisputably the friendliest people in all of Africa hence the nickname. Malawi is home to Africa's third largest lake : Lake Malawi, a shimmering mass of clear water swarming with colorful … More Malawi : Monkey Bay .


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Log Your Memory to later JOG your memory!
This is the Secondary Sidebar Widget Area. You can add content to this area by visiting your Widgets Panel and adding new widgets to this area.
It's hard to believe, but it's already been 3 ½ years since I first launched Log Your Memory… and nearly four years since that first a-ha moment when the idea for the business started to take shape in my brain. During that time, I've published four annual Memory Logbooks in multiple variations and formats, three […]
When you spend as much time online as I do, it's easy to forget sometimes that not everyone else does the same. What has become … Read More
For the first time in a long time, I finally took a break Saturday from the Web & books & all things related to this site … Read More
I was on a bit of a mission yesterday morning. With about an hour to go before I had to be back at the bus stop to pick up my … Read More


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Essay on an influential person
Mar 08, 2016 · Common Application Essay: Overview | Option #1 Tips | Option #2 Tips | Option #3 Tips | Option #4 Tips | Option #5 Tips | Option #6 Tips. The third essay. Meet the most influential people in the world. They are artists and activists, reformers and researchers, heads of state and captains of industry. Their ideas spark. Jun 20, 2016 · Read the essay below, and then continue to the second page to read a critique of the essay. Buck Up. Susan Lewis is a woman that very few people would.
She's the boss. Your browser is out of date. Please update your browser at http://update.microsoft.com Free influential person papers, essays, and research papers.
Essay on an influential person
Thoreau's 1849 essay on the right and obligation to follow your conscience A descriptive essay on an influential person can be about someone who has had a positive or negative impact on your life. This person can be a teacher, a coach, a.
The following list of influential figures from world history comes from Michael H. Hart's book The 100: A Ranking of the Most Influential Persons in History. Check out TIME's annual list. Your browser is out of date. Please update your browser at http://update.microsoft.com
Descriptive Essay About A Person. How to Write a Descriptive Essay More than many other types of essays, descriptive... essays strive to create a deeply involved and. Get TIME photos and pictures of the week delivered directly to your inbox. POTENZA, Inc. is a family of creative, marketing, and digital companies who will help you build, implement, and manage an innovative strategy for your business.
There is not just one person I can say has influenced me to be who I am today. Rather it is really a lot more like my collective family history has impacted who I am. My most influential teacher - Varsity Tutors Scholarship Essay In all my years of schooling I have had many influential teachers. All of my teachers have made a. The Essay Judge +17 : Essay Review: "A Caring Person" Thank you for submitting your university application essay. Let me say first that I think I learn more about. Sample Essays: Influential Person Please select from the following sample application essays: Essay 1: Wellesley | Essay 2: Harvard | Essay 3: Harvard


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Baha'i Points of Interest
List of Posts #1
June 5, 2012
Baha'u'llah identifies "the king of all acts"
The first and foremost duty prescribed unto men, next to the recognition of Him Who is the Eternal Truth, is the duty of steadfastness in His Cause. Cleave thou unto it, and be of them whose minds are firmly fixed and grounded in God. No act, however meritorious, did or can ever compare unto it. It is the king of all acts, and to this thy Lord, the All-Highest, the Most Powerful, will testify....
(Baha'u'llah, Gleanings from the Writings of Baha'u'llah)
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- Yoshimasa Ohmoto, Misao Kataoka, Takashi Miyake, Toyoaki Nishida
- 2011 IEEE International Conference on Granular…
- 2011
The differences in the concepts of values which are the basis of human actions are important when we analyze intercultural communication. The purpose of this study is to estimate emphasizing points for decision-making, which is one of the concepts of values. For this purpose, we experimentally investigate how we could estimate discoveries new factors and… (More)
- Yoshimasa Ohmoto, Misao Kataoka, Toyoaki Nishida
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In 2003, the Japanese government set an approximate goal of 72,000 social hospitalization in-patients being discharged in 10 years from psychiatric hospitals to the community. To meet this challenge, the clinical pathway (CP) is a useful model for managing the team's progress in providing health care services. High quality discharge planning for patients… (More)
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In an interactive decision-making process like a face-to-face consultation (a situation in which subjective information can be obtained), we dynamically change the emphasizing points during the interaction in which an adviser provided new information and subjective interpretations. In previous work, we proposed and evaluated a method to dynamically estimate… (More)
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Over the last six months, we have followed constantly evolving tax scams. Callers have become very good at impersonating IRS agents. Threats of immediate arrest are used to intimidate victims to pay supposed back taxes via Walmart wire service, iTunes gift cards and other prepaid cards. These schemes often target retirees and seniors. Reported taxpayer losses have surpassed $36 million.
IRS Commissioner Koskinen in the cross hairs
This week the House Judiciary Committee reviewed misconduct allegations against the IRS Commissioner John Koskinen. Missing at the hearing was the Commissioner himself. He had sent a written statement defending himself, however.
Federal judge finds Sam Wyly knew system of tax shelters was improper
The latest chapter in a years-long legal saga between the IRS, the SEC, and once-prominent businessman Sam Wyly (and the estate of his late brother Charles) came this week in the form of a 459-page verdict from U.S. Bankruptcy Judge Barbara Houser. The Court found that there is "clear and convincing evidence" that Sam and Charles Wyly knew that their extremely complex and convoluted system of offshore trusts and shell corporations was designed for the sole purpose of hiding profits and other business transactions from the IRS to avoid paying taxes.
Supreme Court rules on California residency case
In our first post of this year, we wrote about a drawn-out dispute between a former California resident and the California tax authorities that went all the way to the U.S. Supreme Court.
IRS staff/budget woes mean fewer audit worries for many
According to information provided by IRS Commissioner John Koskinen, the average American has less of a reason to fear that the "Taxman" cometh (in the form of an audit) than ever before. Congress has slashed the IRS' share of government funds in recent years, and the agency is now dealing with an operating budget of nearly $1 billion less than it was in 2010.
You can't pay back taxes via iTunes
We've covered many tax scams on this blog. Possibly the most common is a caller impersonating an IRS agent. The new variant is that the caller demands you pay your back tax obligation with an iTunes gift card.


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Call us at (732) 721-0475
or click
James Wallace Ryon, died January 2, 2016 at St. Joseph's Hospital in Savannah, GA.
He was born August 19, 1933 in Flint, Michigan, the son of Merle Duffy Ryon and Vera Emma Hamilton Ryon. He Graduated from Flint Central High School, and attended General Motors Institute (now Kettering University) earning the degree of Bachelor of Mechanical Engineering in 1956. He later took post-graduate courses in advanced engineering at the University of Michigan, Horace H. Rackham School of Graduate Studies.
James married Molly Ione Hutchison on March 13, 1954. They had three daughters, Deborah, Kathleen and Nancy. He was a member of the United States Army Reserve, serving on active duty in 1957.
He worked for AC Spark Plug
Division of General Motors Corporation as a Manufacturing Engineer and Supervisor of Process Engineering. He was licensed as a Register Professional Engineer by the State of Michigan in 1971. He retired from AC in 1987. with 36 years of service. He served on the Davison, Michigan Planning Commission for 14 years, and was elected Chairman in 1978. He was appointed Chairman of the City Ordinance Review Board in 1980.
James was actively involved in church and school music activities. He was a member of the AC Spark Plug Male Chorus. He sang in church choirs as a soloist from 1948 until 2008. He enjoyed traveling with Molly and the children, and took one or more long road trips every year. He played tennis and golf, and was an avid reader. He was a Master Mason, a Lifetime Member of Flint Lodge, Number 23, F. & A.M.'s. He has been a member of White Bluff United Methodist Church since moving to Savannah in 2001.
He is survived by his wife of 61 years, Molly Ryon; daughters and sons-in-law: Deborah and Mickey Jones, Kathleen and Daniel Knopoff, Nancy and Frank Canales; five Granddaughters: Melissa Farrell, Michelle Etheridge, Jackie Duncan, Leslie Knopoff, and Sabrina Gager and by eight great-grandchildren: Nachelle Etheredge, Nasean Etheredge, Molly Farrell, Marc Wells, Aubri Wells, Kyle Duncan, Ian Duncan, and Collin Duncan, and by a brother, Larry Ryon and several nieces and nephews.
Visitation: 6 – 7 p.m. Tuesday at Fairhaven Funeral Home, Hubert C. Baker Chapel.
Memorial Service: 7 p.m.Tuesday in the Hubert C. Baker Chapel, with Rev. John Haney, pastor of White Bluff United Methodist Church, officiating.
Interment will be Friday, Jan 8, 2016 at Sunset Hills Memorial Park, in Flint, Michigan 48504.
Fairhaven Funeral Home, Hubert C. Baker Chapel is in charge.
© 2017 Kurzawa Funeral Home, Christine A Cuoco, Manager N.J. Lic. No. 4538
Ph: 732-721-0475


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Royal Liverpool Childrens Hospital
Royal Liverpool Childrens Hospital
Harigopal S.,Royal Infirmary |
Satish H.P.,Royal Liverpool Childrens Hospital |
Taktak A.F.G.,University of Liverpool |
Southern K.W.,Royal Liverpool Childrens Hospital |
Shaw N.J.,Liverpool Womens Hospital
Archives of Disease in Childhood: Fetal and Neonatal Edition | Year: 2011
Aim: To establish a reference range for oxygen saturation (SpO2) in well preterm infants to guide home oxygen therapy using a pulse oximeter and Pulse Oximetry Data Analysis Software (PODS). Methods: SpO2 and heart-Rate profiles of healthy preterm infants receiving mechanical ventilation for less than 6 h and supplemental oxygen for less than 48 h were monitored using a pulse oximeter. The stored data were downloaded from the monitor to a personal computer as individual files. Each infant's files of SpO2 were subsequently displayed in graphic form, and a reference range was constructed using dedicated software, PODS. Results: 43 infants were studied. The median value of all infants mean SpO2 values was 95% (range 92-99%). The median duration of saturations less than 85% and between 85% and 90% were 1% and 2% respectively. Using the study group median, 5th and 95th percentiles, a cumulative frequency curve of time against SpO2 value was constructed (representing the reference range of SpO2 profiles in healthy preterm infants). Conclusion: The SpO2 reference range can be used as an easy and practical guide to compare SpO2 profiles of infants on home oxygen therapy and guide their oxygen therapy.
Koshy G.,Child and Reproductive Health Group |
Delpisheh A.,Child and Reproductive Health Group |
Brabin B.J.,Child and Reproductive Health Group |
Brabin B.J.,Royal Liverpool Childrens Hospital |
Brabin B.J.,University of Amsterdam
European Journal of Public Health | Year: 2011
Background: The combined dose response effects of pregnancy cigarette smoke exposure on childhood overweight, obesity and short stature have not been reported. Method: A community based cross-sectional survey of 3038 children aged 5-11 years from 15 primary schools in Merseyside, UK. Self-completed parental questionnaires were used for family characteristics, socio-economic status and parental smoking practices. Children were measured for height and weight and z-scores calculated for parental smoking categories. Results: Of 689 (34.0) mothers who smoked during pregnancy 50.5 smoked ten or more cigarettes daily (heavy smokers). Children of maternal non-smokers had prevalence estimates for overweight, obesity and short stature of 25, 9.6 and 3.2, respectively. Prevalence estimates were higher in children of mothers who were heavy smokers during pregnancy, 31.5 (P=0.001), 15.6 (P<0.001) and 5.5 (P=0.001), respectively. Mean height for age z-scores was lower among heavy maternal (P<0.001) and paternal smokers (P<0.01) compared to non-smokers. Childhood overweight, obesity or short stature were all associated with heavy maternal smoking during pregnancy (all P<0.001). Mean body mass index (BMI) z-scores were higher in boys of mothers who smoked (P=0.043). The adjusted odds ratio for short stature in children of heavy maternal smokers was 2.76 (95 CI 1.21-6.33) and 4.28 (1.37-13.37) if both parents were heavy smokers. The adjusted OR for obesity in children of maternal smokers was 1.61(1.19-2.18). The population attributable risk for short stature was 8.8 (1.1-22.7) for heavy maternal smokers. Conclusion: A dose-response association was observed between pregnancy smoking exposure, short stature and obesity. © 2010 The Author.
Koshy G.,Child and Reproductive Health Group |
Brabin B.J.,Child and Reproductive Health Group |
Brabin B.J.,Royal Liverpool Childrens Hospital |
Brabin B.J.,University of Amsterdam
BMC Medical Research Methodology | Year: 2012
Background: Compliance is a critical issue for parental questionnaires in school based epidemiological surveys and high compliance is difficult to achieve. The objective of this study was to determine trends and factors associated with parental questionnaire compliance during respiratory health surveys of school children in Merseyside between 1991 and 2006. Methods: Four cross-sectional respiratory health surveys employing a core questionnaire and methodology were conducted in 1991, 1993, 1998 and 2006 among 5-11 year old children in the same 10 schools in Bootle and 5 schools in Wallasey, Merseyside. Parental compliance fell sequentially in consecutive surveys. This analysis aimed to determine the association of questionnaire compliance with variation in response rates to specific questions across surveys, and the demographic profiles for parents of children attending participant schools. Results: Parental questionnaire compliance was 92% (1872/2035) in 1991, 87.4% (3746/4288) in 1993, 78.1% (1964/ 2514) in 1998 and 30.3% (1074/3540) in 2006. The trend to lower compliance in later surveys was consistent across all surveyed schools. Townsend score estimations of socio-economic status did not differ between schools with high or low questionnaire compliance and were comparable across the four surveys with only small differences between responders and non-responders to specific core questions. Respiratory symptom questions were mostly well answered with fewer than 15% of non-responders across all surveys. There were significant differences between mean child age, maternal and paternal smoking prevalence, and maternal employment between the four surveys (all p<0.01). Out-migration did not differ between surveys (p = 0.256) with three quarters of parents resident for at least 3 years in the survey areas. Conclusion: Methodological differences or changes in socio-economic status of respondents between surveys were unlikely to explain compliance differences. Changes in maternal employment patterns may have been contributory. This analysis demonstrates a major shift in community parental questionnaire compliance over a 15 year period to 2006. Parental questionnaire compliance must be factored into survey designs and methodologies. © 2012 Koshy and Brabin; licensee BioMed Central Ltd.
Kulkarni A.V.,Hospital for Sick Children |
Drake J.M.,Hospital for Sick Children |
Kestle J.R.W.,Primary Childrens Medical Center |
Mallucci C.L.,Royal Liverpool Childrens Hospital |
And 2 more authors.
Neurosurgery | Year: 2010
Background: Endoscopic third ventriculostomy (ETV) has preferentially been offered to patients with more favorable prognostic features compared with shunt. Objective: To use advanced statistical methods to adjust for treatment selection bias to determine whether ETV survival is superior to shunt survival once the bias of patient-related prognostic factors is removed. Methods: An international cohort of children (≤ 19 years of age) with newly diagnosed hydrocephalus treated with ETV (n = 489) or shunt (n = 720) was analyzed. We used propensity score adjustment techniques to account for 2 important patient prognostic factors: age and cause of hydrocephalus. Cox regression survival analysis was performed to compare time-to-treatment failure in an unadjusted model and 3 propensity score-adjusted models, each of which would adjust for the imbalance in prognostic factors. Results: In the unadjusted Cox model, the ETV failure rate was lower than the shunt failure rate from the immediate postoperative phase and became even more favorable with longer duration from surgery. Once patient prognostic factors were corrected for in the 3 adjusted models, however, the early failure rate for ETV was higher than that for shunt. It was only after about 3 months after surgery did the ETV failure rate become lower than the shunt failure rate. CONCLUSIONS: The relative risk of ETV failure is initially higher than that for shunt, but after about 3 months, the relative risk becomes progressively lower for ETV. Therefore, after the early high-risk period of ETV failure, a patient could experience a long-term treatment survival advantage compared with shunt. It might take several years, however, to realize this benefit. © 2010 by the Congress of Neurological Surgeons.
Burwell R.G.,University of Nottingham |
Dangerfield P.H.,University of Liverpool |
Dangerfield P.H.,Staffordshire University |
Dangerfield P.H.,Royal Liverpool Childrens Hospital
Studies in Health Technology and Informatics | Year: 2012
Although considerable progress had been made in the past two decades in understanding the etiopathogenesis of adolescent idiopathic scoliosis (AIS), it still lacks an agreed theory of etiopathogenesis. One problem may be that AIS results not from one cause, but several that interact with various genetic predisposing factors. There is a view there are two other pathogenic processes for idiopathic scoliosis namely, initiating (or inducing), and those that cause curve progression. Twin studies and observations of family aggregation have revealed significant genetic contributions to idiopathic scoliosis, that place AIS among other common disease or complex traits with a high heritability interpreted by the genetic variant hypothesis of disease. We summarize etiopathogenetic knowledge of AIS as theories of pathogenesis including recent multiple concepts, and blood tests for AIS based on predictive biomarkers and genetic variants that signify disease risk. There is increasing evidence for the possibility of an underlying neurological disorder for AIS, research which holds promise. Like brain research, most AIS workers focus on their own corner and there is a need for greater integration of research effort. Epigenetics, a relatively recent field, evaluates factors concerned with gene expression in relation to environment, disease, normal development and aging, with a complex regulation across the genome during the first decade of life. Research on the role of environmental factors, epigenetics and chronic noncommunicable diseases (NCDs) including adiposity, after a slow start, has exploded in the last decade. Not so for AIS research and the environment where, except for monozygotic twin studies, there are only sporadic reports to suggest that environmental factors are at work in etiology. Here, we examine epigenetic concepts as they may relate to human development, normal life history phases and AIS pathogenesis. Although AIS is not regarded as an NCD, like them, it is associated with whole organism metabolic phenomena, including lower body mass index, lower circulating leptin levels and other systemic disorders. Some epigenetic research applied to Silver-Russell syndrome and adiposity is examined, from which suggestions are made for consideration of AIS epigenetic research, cross-sectional and longitudinal. The word scoliogeny is suggested to include etiology, pathogenesis and pathomechanism. © 2012 The authors and IOS Press. All rights reserved.
Nayagam S.,Royal Liverpool Childrens Hospital |
Davis B.,Norfolk and Norwich NHS Foundation Trust |
Thevendran G.,Tan Tock Seng Hospital |
Roche A.J.,Chelsea and Westminster Hospital NHS Foundation Trust
Bone and Joint Journal | Year: 2014
We describe the technique and results of medial submuscular plating of the femur in paediatric patients and discuss its indications and limitations. Specifically, the technique is used as part of a plate-after-lengthening strategy, where the period of external fixation is reduced and the plate introduced by avoiding direct contact with the lateral entry wounds of the external fixator pins. The technique emphasises that vastus medialis is interposed between the plate and the vascular structures. A total of 16 patients (11 male and five female, mean age 9.6 years (5 to 17)), had medial submuscular plating of the femur. All underwent distraction osteogenesis of the femur with a mean lengthening of 4.99 cm (3.2 to 12) prior to plating. All patients achieved consolidation of the regenerate without deformity. The mean follow-up was 10.5 months (7 to 15) after plating for those with plates still in situ, and 16.3 months (1 to 39) for those who subsequently had their plates removed. None developed a deep infection. In two patients a proximal screw fractured without loss of alignment; one patient sustained a traumatic fracture six months after removal of the plate. Placing the plate on the medial side is advantageous when the external fixator is present on the lateral side, and is biomechanically optimal in the presence of a femoral defect. We conclude that medial femoral submuscular plating is a useful technique for specific indications and can be performed safely with a prior understanding of the regional anatomy. © 2014 The British Editorial Society of Bone & Joint Surgery.
Gartshore L.,Royal Liverpool Childrens Hospital
British Journal of Oral and Maxillofacial Surgery | Year: 2010
In 1901, René Le Fort conducted some of the most infamous experiments known to maxillofacial surgery. He was an interesting and highly accomplished man with experience in many fields of surgery. We continue to use much of his research today despite many advances in medicine, yet we know little about the man himself.The aim of this short paper is to introduce you to René Le Fort and to describe the highlights of his experiments, which gave rise to a system of classifying facial fractures. © 2009 The British Association of Oral and Maxillofacial Surgeons.
Gladman G.,Royal Liverpool Childrens Hospital
Paediatrics and Child Health (United Kingdom) | Year: 2013
Asymptomatic cardiac murmurs are a common finding in paediatric patients with some estimates suggesting that 90% of children have a murmur detected at some stage. Most are benign 'innocent' noises or reflect minor structural heart disease of no haemodynamic significance. The degree of parental anxiety invoked by the detection of a murmur in their child is considerable and although in virtually all cases their concerns of significant underlying cardiac disease are unjustified, providing adequate reassurance is a challenge for the health professionals involved. The aim of this article is to guide practitioners in determining which babies or children need urgent referral for a specialist opinion and to provide management suggestions for when a murmur is noted coincidentally during a routine examination. © 2012.
Thompson S.M.,University of Liverpool |
Jesudason E.C.,Royal Liverpool Childrens Hospital |
Turnbull J.E.,University of Liverpool |
Fernig D.G.,University of Liverpool
Birth Defects Research Part C - Embryo Today: Reviews | Year: 2010
Heparan sulfate (HS) is a structurally complex polysaccharide located on the cell surface and in the extracellular matrix, where it participates in numerous biological processes through interactions with a vast number of regulatory proteins such as growth factors and morphogens. HS is crucial for lung development; disruption of HS synthesis in flies and mice results in a major aberration of airway branching, and in mice, it results in neonatal death as a consequence of malformed lungs and respiratory distress. Epithelial-mesenchymal interactions governing lung morphogenesis are directed by various diffusible proteins, many of which bind to, and are regulated by HS, including fibroblast growth factors, sonic hedgehog, and bone morphogenetic proteins. The majority of research into the molecular mechanisms underlying defective lung morphogenesis and pulmonary pathologies, such as bronchopulmonary dysplasia and pulmonary hypoplasia associated with congenital diaphragmatic hernia (CDH), has focused on abnormal protein expression. The potential contribution of HS to abnormalities of lung development has yet to be explored to any significant extent, which is somewhat surprising given the abnormal lung phenotype exhibited by mutant mice synthesizing abnormal HS. This review summarizes our current understanding of the role of HS and HS-binding proteins in lung morphogenesis and will present in vitro and in vivo evidence for the fundamental importance of HS in airway development. Finally, we will discuss the future possibility of HS-based therapeutics for ameliorating insufficient lung growth associated with lung diseases such as CDH. © 2010 Wiley-Liss, Inc.
Baillie C.T.,Royal Liverpool Childrens Hospital |
Smith J.A.,Royal Liverpool Childrens Hospital
World Journal of Gastroenterology | Year: 2015
Inflammatory bowel disease (IBD) comprises two distinct but related chronic relapsing inflammatory conditions affecting different parts of the gastrointestinal tract. Crohn's disease is characterised by a patchy transmural inflammation affecting both small and large bowel segments with several distinct phenotypic presentations. Ulcerative colitis classically presents as mucosal inflammation of the rectosigmoid (distal colitis), variably extending in a contiguous manner more proximally through the colon but not beyond the caecum (pancolitis). This article highlights aspects of the presentation, diagnosis, and management of IBD that have relevance for paediatric practice with particular emphasis on surgical considerations. Since 25% of IBD cases present in childhood or teenage years, the unique considerations and challenges of paediatric management should be widely appreciated. Conversely, we argue that the organizational separation of the paediatric and adult healthcare worlds has often resulted in late adoption of new approaches particularly in paediatric surgical practice. © The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.


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pts rule name description ---- ---------------------- -------------------------------------------------- 3.0 DEAR_BENEFICIARY BODY: Dear Beneficiary: 0.0 TVD_RCVD_IP4 Message was received from an IPv4 address 0.0 TVD_RCVD_IP Message was received from an IP address 0.0 FREEMAIL_FROM Sender email is commonly abused enduser mail provider (vania.zanier[at]alice.it) 1.6 SUBJ_ALL_CAPS Subject is all capitals 0.2 FREEMAIL_REPLYTO_END_DIGIT Reply-To freemail username ends in digit (moneygram234[at]hotmail.com ) 1.2 MISSING_HEADERS Missing To: header 0.0 LOTS_OF_MONEY Huge... sums of money 1.2 UPPERCASE_75_100 message body is 75-100% uppercase 1.9 REPLYTO_WITHOUT_TO_CC REPLYTO_WITHOUT_TO_CC 1.0 FREEMAIL_REPLYTO Reply-To/From or Reply-To/body contain different freemails 1.0 MONEY_FROM_41 Lots of money from Africa 1.0 SPOOFED_FREEM_REPTO Forged freemail sender with freemail reply-to 1.0 MONEY_FRAUD_5 Lots of money and many fraud phrases 2.8 ADVANCE_FEE_3_NEW_MONEY Advance Fee fraud and lots of money
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text:
Thomas Jefferson to Thomas Taylor, 28 December 1814
To Thomas Taylor
Monticello Dec. 28. 14.
I recieved yesterday evening your favor of the 19th & answer it without delay, that no laches may be imputed as to notice of my right, & that of others interested in the lots & streets of the town of Beverley. I do not comprehend what mr Wilson understands by saying that 'the right to lots in that town reverted to the original proprietors, from whom he purchased, and they having conveyed to him a general warranty, he does not admit my claim.' here seems to be error both of law and fact. of law, because, by that, in no event could these lots revert to the original proprietor. of fact, because the late Colo Byrd, or rather his father, was the original proprietor, and I am confident that Colo Byrd never sold the site of Beverley town to mr Wilson, or any other than the purchasers of the lots. mr Wilson may have purchased of the original trespassor, who inclosed the whole town I believe about 10. or a dozen years ago, whose general warranty may bind his own lands to mr Wilson, but not those of others.
The town of Beverley was laid off on the 6th of June 1751. under an act of assembly then recently passed. the original1 plan of the town, signed by Peter Randolph as Commissioner or Trustee, and by Peter Jefferson (my father) who surveyed, and marked the lots and streets by metes & bounds, was recorded in Henrico court, & the No of every lot, and name of the purchaser written within the lot. of this I have a copy with the following authentication. 'a copy from the plan of the town of Beverley now remaining in the office of Henrico county court, test J. Beckley D. clk for Thomas Adams Clk.' if the original was among the records destroyed by the British, still, my copy, being an authentic one, is sufficient evidence of the titles. the lots I hold there are by the double right of descent & devise from my father.2 I was a boy of about 8. years age, living with my father at Tuckahoe, when this transaction took place, and well remember his going to Westham to lay off the town, and his mentioning the price at which the lots were sold, which was a doubloon (£4–6) apiece the purchasers drawing their numbers (if I recollect) by lot, and not chusing them. Westham was then the landing for all the produce coming down James river; and was therefore expected to become a place of consequence, & the lots were chiefly bought by the landholders above, with a view to providing some cover there for their tobacco; the annual loss on which was considerable from it's lying exposed on the bank, until it could be waggoned away. a ferry was established from the uppermost lot on the river No 151. to the lands of one Britton on the opposite side who, on his own right on that side, kept the ferry till after the revolution, for I remember crossing there during that. whether he paid any rent to my father for the use of the landing on the ferry lot on this side, I do not know. I never recieved nor required any from him. the opening the James river canal put an end to the value of lots in this town as a depot, except the ferry lot, which must in time become of value, because the falls render any other ferry impracticable from thence to Richmd. the sense of duty which you express of protecting the purchaser against a false title, as well as of procuring the best price for the seller is perfectly just and honorable; and it is to enable you to do that that I trouble you with this letter, to which, on behalf of the other claimants, I will subjoin a list of the original purchasers, and of the lots now claimable under them. considering the continuance of that town as without an object at present, I shall have no objection, in conjunction with as many of the other claimants as can be found, to consent to the passage of an act of assembly repealing the former one, and ordering a sale of the whole site, lots and streets, for the benefit of the owners of the lots, so as to restore the ground to agriculture, for which alone it is fit; but, mr Wilson's justice will say, let this be done by law, & for the benefit of the owners who paid upwards of 1500.D. for the lots & streets 63. years ago, and not for that of the intruder, or to exonerate him of his warranty to those claiming under him, and saving also the ferry lot & road to it, which is the only one now having any value but merely as ground for cultivation. the original purchasers having been almost entirely landholders on James river, most of their families still remain and can be brought forward to act in conjunction by the newspapers. or if any more practicable or reasonable proposition can be made, I shall not obstruct it. Accept the assurance of my great esteem and respect.
Th: Jefferson
PoC (MHi); at foot of first page: "Mr Thomas Taylor"; written on one sheet folded to form four pages, with letter on pp. 1–2 and enclosure described below on pp. 3–4; endorsed by TJ on p. 4.
The act establishing the town of Beverley became law in February 1752, and so it was most likely laid off in June of that year rather than in 1751 as indicated above (Hening, description begins William Waller Hening, ed., The Statutes at Large; being a Collection of all the Laws of Virginia, Richmond, 1809–23, 13 vols.; Sowerby, no. 1863; Poor, Jefferson's Library, 10 (no. 573) description ends 6:273–4). The copy from the plan of the town, which is indeed dated 6 June 1751, is in ViU: TJP-ER. Just prior to the American Revolution, John James Beckley spent some time as the deputy clerk (d. clk) of Henrico County under Thomas Adams (DVB description begins John T. Kneebone and others, eds., Dictionary of Virginia Biography, 1998– , 3 vols. description ends ). The extension of the james river canal past the falls above Richmond in 1800 greatly reduced the value of Beverley's lots (MB description begins James A. Bear Jr. and Lucia C. Stanton, eds., Jefferson's Memorandum Books: Accounts, with Legal Records and Miscellany, 1767–1826, 1997, The Papers of Thomas Jefferson, Second Series description ends , 2:1326n).
The alphabetical list of the original seventy-eight purchasers was most likely drawn from the above plan of Beverley. It identifies the purchasers and their lots and, more often than not, provides additional data about the buyers, such as "the former inspector, or perhaps his father," "of Richmond presumably," "English merchant," "has descendants in Buckingham," and "this [John Roberts] might be the steward of old Colo J. Bolling at Licking hole." Peter Jefferson is shown to have acquired lots 57, 107–8, and 151, with the last being the ferry lot. Other purchasers of note and relatives and acquaintances of TJ include Peter Jefferson's surveying colleagues William Cabell (lots 6, 18, 31, 51, 87, 100) and Joshua Fry (lots 83, 117–8); John Bolling ("of Cobbs in Chesterfield, grand father of it's present proprietor"; lots 49, 95); Carter Braxton, a signer of the Declaration of Independence ("of York river"; lots 105–6, 154–6); John Fleming ("father of the judge, or brother"; lot 20); TJ's guardian John Harvie (1706–67; "father of the late Colo John Harvey of Richmond"; lot 27); James Skelton ("owner of Elk island"; lot 21); William Stith ("Presidt of W. M. College"; lot 77); John Woodson ("known by the name of Courthouse John"; lot 5); and John Woodson ("known by the name of Sheriff John"; lot 2). In a box in the lower right corner of the final page, TJ provides more general information about the property:
|"156. lots of half an acre each.
|40. of them are blank, probably Colo Byrds, to wit, Nos 46. 101–104. 111.–106. [i.e. 116] 121.–129. 131–150.
|width of the town on the river about
|extent from the river, medium abt
|contents about 115. acres.
|the ferry lot is 18. poles on the river, abt 3. po. wide
|each lot with it's proportion of street is abt ¾ acre"
(PoC in MHi; entirely in TJ's hand; undated; subjoined to PoC of covering letter).
1. Word interlined.
2. Preceding three words interlined.
Index Entries
- Adams, Thomas; Henrico Co. clerk search
- Beckley, John James; as Henrico Co. deputy clerk search
- Bolling, John (d.1757); and Westham land search
- Braxton, Carter; buys lots in Westham search
- Britton, Anderson; operates ferry search
- Byrd, William (1674–1744); and Westham land search
- Byrd, William (1728–77); and Westham land search
- Cabell, William (1700–74); buys lots in Westham search
- canals; on James River search
- Fleming, John (1697–1756); mentioned search
- Fleming, John (d.1767); mentioned search
- Fleming, William; mentioned search
- Fry, Joshua; buys lots in Westham search
- Harvie, John (1706–67); buys lot in Westham search
- Harvie, John (1742–1807); mentioned search
- James River; canal search
- Jefferson, Peter (TJ's father); and Westham land search
- Randolph, Peter (d.1767); and Westham land search
- Roberts, John; and Westham land search
- Skelton, James; buys lot in Westham search
- Stith, William; buys lot in Westham search
- Taylor, Thomas; and sale of Westham land search
- Taylor, Thomas; letters to search
- tobacco; grown in Va. search
- Tuckahoe (Randolph family's Goochland Co. estate); TJ's early life at search
- Westham, Va.; ferry and landing at search
- Westham, Va.; original purchasers of lots in search
- Westham, Va.; plan and survey of search
- Westham, Va.; proposed sale of search
- Westham, Va.; TJ's lots in search
- Wilson, Thomas; and Westham land search
- Woodson, John ("Courthouse John"); buys lot in Westham search
- Woodson, John ("Sheriff John"); buys lot in Westham search


text:
Alle Embedded Software Developer - Jobs in München
Alle Embedded Software Developer - Jobs
Alle Jobs in München
Embedded Software Developer (f/m) Focus Low level programmingArbeitsort: D-81541 München · Bayern
- Anbieter:
- ESR.Labs
- Arbeitsverhältnis:
- Festanstellung
- Arbeitszeit:
- Vollzeit
- Vergütung:
- monatliches Festgehalt
- Anzeige vom:
- 16.10.2017 (2 Tage alt)
Embedded Software Developer (f/m) Focus Low level programming
For this role you can choose where to build your career with us in Germany: At our exciting new offices in the Neue Balan "Campus of Ideas" in wonderful Munich, ranked as one of the world's most liveable and interesting cities. Or you can join us at our smaller offices in beautiful Kulmbach.
What does your work life look like with us?
As Embedded Software Developer with focus on low-level programming, you take on very demanding projects, usually in cooperation with leading OEMs. You develop drivers for 32-bit controllers in cooperation with well-known micro controller manufacturers. Rather than adjusting pre-existing low level drivers, you write these drivers in C++ from scratch on the basis of very specific and complex requirements. PowerPC architectures support you in the implementation.
What we expect from you? Required:
• Excellent teamwork capability
• Excellent knowledge of C++
• Good knowledge in driver development (32bit Controller)
• Embedded expertise
• Good English language skills
• Ready to make a strong commitment to both the customer and to the team
• Willingness to familiarize yourself with large, complex standards
What we expect from you? Desired:
• Completed degree in Information Technology or comparable education
• Basic understanding of PowerPC architectures
• Knowledge of agile software development
• German language skills
What you can expect from us
• Diverse and interesting tasks
• Co-workers with expert-level knowledge
• Exciting and motivating work environment
• Projects which will challenge you to excel
• Flexible work-hour models
• Freedom to choose your own setup: you select the equipment and tools you want to work with
• The chance to have fun and learn new things at our regular hackathons, programming challenges and hands-on workshops
Our vision: Leave a fingerprint in the software industry!
Your application will be processed by our strategic recruiting partner.
Englisch (fließend/verhandlungssicher)
- Ort:
- München
- Postleitzahl:
- Bundesland:
- Bayern
- Land:
- Deutschland
- Regierungsbezirk:
- Oberbayern
- Landkreis:
- Kreisfreie Stadt München


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The Nigerian Military has received twenty nine mine-resisted and armour-protected vehicles from the United States as part of efforts to fighting the current security challenge in the country.
The United States has donated $11 million mine-resistant and armor-protected vehicles to the Nigerian army.
MaxxPro MRAP (Mine Resistant Ambush Protected) vehicles donated by the U.S government
A statement issued by the public affairs section of the United States Consulate General in Lagos said the vehicles valued at $11 million were handed over to the military authorities on Thursday at the Nigerian army 9th brigade parade ground, Ikeja army cantonment in Lagos, South Western Nigeria.
The Nigerian Minister of Defence, represented by Major-General Barry Ndiomu, who received the donation on their behalf also inspected the U.S Armored Personnel Carrier in Lagos.
The statement read: "The US is pleased to donate 24 mine-resistant, armor-protected (MRAP) vehicles valued at $11 million to Nigeria's military authorities.
"The equipment donation represents part of the continuing US commitment to Nigeria and its neighbours to counter Boko Haram's senseless acts of terror and promote regional security."
Earlier, the United States Ambassador to Nigeria, James Entwistle, had re-emphasized the country's commitment to assist Nigeria in its fight against boko haram.


text:
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A short monograph on clinical pharmacology and therapeutic use of propranolol and related drugs in arrhythmias, angina pectoris, myocardial infarction, hypertrophic subaortic stenosis, pheochromocytoma, thyrotoxicosis, tetralogy of Fallot, hypertension, parkinsonism, mitral stenosis, and circulatory shock. References and a subject index.
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Circulatory Effects and Clinical Uses of Beta-Adrenergic Blocking Drugs.. Ann Intern Med. 1972;77:342. doi: 10.7326/0003-4819-77-2-342_2
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© 2017
Published: Ann Intern Med. 1972;77(2):342.
Copyright © 2017 American College of Physicians. All Rights Reserved.
Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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