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The work was led by Professor Martin Howard and Professor Caroline Dean at the John Innes Centre, which receives strategic funding from BBSRC. Funding for the project came from BBSRC, the European Research Council, and The Royal Society.
Professor Dean said "There are quite a few examples that we now know of where the activity of genes can be affected in the long term by environmental factors. And in some cases the environment of an individual can actually affect the biology or physiology of their offspring but there is no change to the genome sequence."
For example, some studies have shown that in families where there was a severe food shortage in the grandparents' generation, the children and grandchildren have a greater risk of cardiovascular disease and diabetes, which could be explained by epigenetic memory. But until now there hasn't been a clear mechanism to explain how individuals could develop a "memory" of a variable factor, such as nutrition.
The team used the example of how plants "remember" the length of the cold winter period in order to exquisitely time flowering so that pollination, development, seed dispersal and germination can all happen at the appropriate time.
Professor Howard said "We already knew quite a lot about the genes involved in flowering and it was clear that something goes on in winter that affects the timing of flowering, according to the length of the cold period."
Using a combination of mathematical modelling and experimental analysis the team has uncovered the system by which a key gene called FLC is either completely off or completely on in any one cell and also later in its progeny. They found that the longer the cold period, the higher the proportion of cells that have FLC stably flipped to the off position. This delays flowering and is down to a phenomenon known as epigenetic memory.
Epigenetic memory comes in various guises, but one important form involves histones - the proteins around which DNA is wrapped. Particular chemical modifications can be attached to histones and these modifications can then affect the expression of nearby genes, turning them on or off. These modifications can be inherited by daughter cells, when the cells divide, and if they occur in the cells that form gametes (e.g. sperm in mammals or pollen in plants) then they can also pass on to offspring.
Together with Dr Andrew Angel (also at the John Innes Centre), Professor Howard produced a mathematical model of the FLC system. The model predicted that inside each individual cell, the FLC gene should be either completely activated or completely silenced, with the fraction of cells switching to the silenced state increasing with longer periods of cold.
To provide experimental evidence to back up the model, Dr Jie Song in Prof. Dean's group used a technique where any cell that had the FLC gene switched on, showed up blue under a microscope. From her observations, it was clear that cells were either completely switched or not switched at all, in agreement with the theory.
Dr Song also showed that the histone proteins near the FLC gene were modified during the cold period, in such a way that would account for the switching off of the gene.
Professor Douglas Kell, Chief Executive, BBSRC said "This work not only gives us insight into a phenomenon that is crucial for future food security – the timing of flowering according to climate variation – but it uncovers an important mechanism that is at play right across biology. This is a great example of where the research that BBSRC funds can provide not only a focus on real life problems, but also a grounding in the fundamental tenets of biology that will underpin the future of the field. It also demonstrates the value of multidisciplinary working at the interface between biology, physics and mathematics."
Nancy Mendoza | EurekAlert!
Further information:
Further reports about: > BBSRC > Pollination > biological memory > biological sciences > bird songs > cardiovascular disease > environmental factors > epigenetic > future food security > histone proteins > mathematical model > pollen in plants
Could this protein protect people against coronary artery disease?
17.11.2017 | University of North Carolina Health Care
Microbial resident enables beetles to feed on a leafy diet
17.11.2017 | Max-Planck-Institut für chemische Ökologie
The formation of stars in distant galaxies is still largely unexplored. For the first time, astron-omers at the University of Geneva have now been able to closely observe a star system six billion light-years away. In doing so, they are confirming earlier simulations made by the University of Zurich. One special effect is made possible by the multiple reflections of images that run through the cosmos like a snake.
Today, astronomers have a pretty accurate idea of how stars were formed in the recent cosmic past. But do these laws also apply to older galaxies? For around a...
Just because someone is smart and well-motivated doesn't mean he or she can learn the visual skills needed to excel at tasks like matching fingerprints, interpreting medical X-rays, keeping track of aircraft on radar displays or forensic face matching.
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Computer Tomography (CT) is a standard procedure in hospitals, but so far, the technology has not been suitable for imaging extremely small objects. In PNAS, a team from the Technical University of Munich (TUM) describes a Nano-CT device that creates three-dimensional x-ray images at resolutions up to 100 nanometers. The first test application: Together with colleagues from the University of Kassel and Helmholtz-Zentrum Geesthacht the researchers analyzed the locomotory system of a velvet worm.
During a CT analysis, the object under investigation is x-rayed and a detector measures the respective amount of radiation absorbed from various angles....
The quantum world is fragile; error correction codes are needed to protect the information stored in a quantum object from the deteriorating effects of noise. Quantum physicists in Innsbruck have developed a protocol to pass quantum information between differently encoded building blocks of a future quantum computer, such as processors and memories. Scientists may use this protocol in the future to build a data bus for quantum computers. The researchers have published their work in the journal Nature Communications.
Future quantum computers will be able to solve problems where conventional computers fail today. We are still far away from any large-scale implementation,...
Pillared graphene would transfer heat better if the theoretical material had a few asymmetric junctions that caused wrinkles, according to Rice University...
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The importance of biodiversity in forests could increase due to climate change
17.11.2017 | Studies and Analyses


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Jimmy Coates: Killer
Written by Joe Craig
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The Lovereading4Kids comment
The first in a new action series that has been a huge hit with fans of Alex Rider. Jimmy has led a pretty normal life until at 11 he begins to develop extraordinary powers. To start with this is pretty cool until he is being chased by the British secret service, as these powers are a result of extreme genetic engineering – the aim of which is to make Jimmy a weapon.
All action, great characters guaranteed to get your 12+ boys reading late into the night. If you like Jimmy Coates Killer then Jimmy Coates Target is now available in paperback.
To read the series in order start with Killer, then Target, then Revenge and finally the newest Sabotage.
Jimmy Coates: Killer by Joe Craig
Bending his knees, Jimmy let go of the windowsill and slowly tipped backwards. Surely this is impossible, he thought, even as he could feel himself doing it. He pushed out with his legs and the thrust sent him flying backwards into the air… Then his fingers locked on to the cold wire of the fence, poised in a perfect handstand on the top.
Who are the mysterious men chasing Jimmy across the city?
Why are they after him?
What are Jimmy's parents keeping from him and who can he trust?
And how come he can suddenly do all this really cool stuff…?
Find out in this electrifying debut novel from Joe Craig. Young, multitalented and brimming with ideas, this new HarperCollins author is destined to become a firm favourite with children everywhere.
"…a totally excellent adventure – a lit bit Bond, a lit bit Matrix and a lot of what you've never read before. Someone make this into a movie!" Flipside
"A gripping action-thriller that's packed with twists." Funday Times
"The perfect primer to the Bourne series by Robert Ludlum." VOYA
About the Author
Other Formats
Book Info
304 pages
Interest Age: From 9 years
Joe Craig
More books by Joe Craig
Author's Website
Harpercollins Publishers
Publication date
31st March 2005
I love Lovereading4kids because I get an opportunity to put my opinion forward and to try new booksElosie Clarkson – age 11
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It has introduced my children to books we hadn't come across before. Real children's reviews gives a great insight into what others think toLorraine Woods
We love Lovereading4kids because it promotes reading choices, new authors and a sense of community for children of all ages!Rachel Bridgeman

subset: commoncrawl


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text: 12/15/15 Town Board Meeting Agenda Dec 15, 2015 Posted by Marbletown In News Final Agenda for 12/15/15 Town Board Meeting 12.15.2015TOWNBOARDAGENDA Related Posts Transfer Station will be CLOSED on Friday, Nov. 24th and OPEN on Sat. Nov. 25th Town Offices will be CLOSED on Thursday Nov. 23rd and Friday, Nov. 24th 11/21/17 Town Board Meeting Agenda Rifle Hunting Season Opens Sat. 11/18 and runs through 12/10


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Best vacation web site design jobs
...age) now available! All Swimstruct staff are Austswim or RLSSWA qualified Event Dates: Afternoon Series 2/12/17 – 11/12/17 Vacation 1 series 15/12/17 – 24/12/17 Vacation 2 series 3/1/18 – 12/1/18 Vacation 3 series 16/1/18 – 25/1/18 Weekend series 27/1/18 – 25/2/18 Location: St. Marys Anglican Girls School Karrinyup Swimming Poo...
I need create a spreadsheet that would tell the employees how many hours and days of vacation they in Kuwait and Jordan
...is to download the app, if it works for your device, give it highest ratings(hopefully) and leave a nice comment. A winner will be picked from a pool of the highest raters & best comments. Constructive criticism can be channeled through the "Send email" in the developer section at the bottom of the apps playstore page. The name of the app is "Flashlight
...plastic material. We want to be able to ship a small desk top device to our customers so they can chop up the DVDs before they ship to us for recycling. This contest is to design an environmentally safe desktop device that chops up the plastic material contained in a DVD disk in 10 seconds or less to pieces no larger then 2.5mm by 2.5mm. The device
...says [url removed, login to view] Again - this is Vacation DOT Rentals. Our brand is a little fox called Alpu, LLC. Alpu is Trademarked and I would like that shown in the design. I think the word Vacation should be slightly to the left and on top of the word Rentals. The head of the fox will be the DOT between Vacation and Rentals Underneath the whole
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This job sought for a freelance position processing mail, developing correspondence, verifying data.
I need a stored procedure that will read in columns EmpID,R...alphabetical and also a parameter for grouping by groups(with subtotals). showing daily, weekly and bi-weekly totals of standard hours overtime (standardHours > 40 per week) Vacation, Holiday, Funeral, Sick, and other paid absent types (bool) Bonus if done within 24 hours.
Hi, I have a vacation rental website. Previous freelancer left in-between after supplying him domain and admin login. I want someone make my website working quick as possible. It must work like homeaway, airbnb etc but not a copy of it. Please bid only if you can do this job. I need following added:- 1. Signup 2. Login 3. Submit Property
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...need 4 sites developed on online sharepoint: - site for submitting internal requests (e.g. vacation, changes and incidents reporting..) that will be approved by a designated person - site for uploading relevant literature and searching through the e-library (by document name, tags etc.) - site for managing proposals - basic workflow which will
We are the well-known website AirBnB. Airbnb is an online marketplace and hospitality service, enabling people to lease or rent short-term lodging including vacation rentals, apartment rentals, homestays, hostel beds, or hotel rooms. The mission is very simple, we provide you with a list of 50 housing offers and you must rank them in order of preference
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edoko sushi buffet on university is a great value for what you get, I have never had better buffet sushi. The rice is cooked extremley well and the fish is not dried out like in other sushi buffets it is still fresh.
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Jason Towns
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On tap right now we have the sales trailer for the new flick from Matchbox Pictures (Devil Seed) entitled Kingdom Come. Check it out, and look for more on this one soon!
Directed by Greg A. Sager, the flick stars Ryan Barrett and Camille Hollet-French as the leads "Sam Becker" and "Jessica Martin." Jason Martorino, Soroush Saeidi, Jo Jo Karume, Chelsey Marie, William Foley, and Katie Uhlmann also star with Elle O'Brien making her feature film debut. The flick will be making the rounds at Cannes courtesy of Imagination Worldwide!
A group of strangers awake, trapped inside an old abandoned mental hospital. With no apparent way out and no one being able to remember how they even got there, they begin searching for a way to escape. As they explore the cold, dark maze of corridors, they realize they are not alone and that they are being stalked by supernatural forces with sinister intentions.
For Sam (Ry Barrett) and Jessica (Camille Hollett-French), keeping Celia (Ellie O'Brien), the youngest member, safe proves to be just as difficult as keeping the group together as hostilities grow between them. Everyone begins to question each other's motives as secrets linking their pasts are revealed and someone within the group is not who they say they are. One by one they begin to disappear; all that is left behind to be found by the others is the devastation and carnage of their demise.
As everything and everyone unravels, they start to understand that all the windows that have been boarded up from the inside are not so much there to keep them in, but to keep whatever evil lurks outside…out. In this place nothing is as it seems, and the decisions they make here will seal their fate forever.
Got news? Click here to submit it!
Come in your kingdom in the comments section below.
The Duffer Brothers Have Begun Working on Stranger Things 3
I wasn't the world's biggest fan of the first season of Netflix and The Duffer Brothers' "Stranger Things" to tell you the truth. That said, I absolutely loved the second season (read out reviews HERE).
It is with his in mind that we are all looking forward to "Stranger Things 3".
Recently Deadline reported that at Vulture Festival LA, the Duffer Brothers, producer Shawn Levy, Finn Wolfhard, Paul Reiser, and Linnea Berthelsen talked about season two and tease season three.
"We are [in] very early days on season three and we're still figuring it out," Ross Duffer said, before taking a beat, then adding: "I probably wasn't supposed to say that. That's not official, that wasn't an official announcement — we're just working on it, just for our own amusement…for fun!"
We all know at this point that there is going to be a "Stranger Things 3" and that The Duffer Brothers will one day begin working on it. Don't worry so much, Ross Duffer.
After all, your brother already let us know that season three will begin after a time jump:
"Even if we wanted to hop into the action faster, we couldn't," says Matt Duffer. "Our kids are aging. We can only write and produce the show so fast. They're going to be almost a year older by the time we start shooting season three. It provides certain challenges. You can't start right after season two ended. It forces you to do a time jump. It's a long way of saying that yeah, we're going to do a time jump."
What did you think of "Stranger Things 2"? Did you dig it more (or less) than season one? Make sure to hit us up and let us know in the comments below or on social media!
"Stranger Things 2" is currently streaming on Netflix.
It's 1984 and the citizens of Hawkins, Indiana are still reeling from the horrors of the Demogorgon and the secrets of Hawkins Lab. Will Byers has been rescued from the Upside Down but a bigger, sinister entity still threatens those who survived.
James Cameron's Terminator Reboot/Sequel Hires Screenwriter
The last word we brought you guys on producer James Cameron and Deadpool-director Tim Miller's new Terminator film was when we let you know that Paramount had set the film's release date for July 26, 2019.
Today we have news via The Wrap that the studio is bringing in screenwriter Billy Ray (Captain Phillips) to pen the movie's script based on a story crafted by Cameron.
You may remember that Cameron and Miller created a writers room a while back to plan out an all-new trilogy of films, but while that writer's room included David Goyer, Charles Eglee, and Josh Friedman, it seems like Ray will be the first film's sole writer. For now.
Story details are, of course, being kept under wraps, but Cameron and Miller are treating the new movie as a direct sequel to Cameron's T2: Judgment Day.
"This is a continuation of the story from 'Terminator 1' and 'Terminator 2.' And we're pretending the other films were a bad dream," Cameron told THR. "Or an alternate timeline, which is permissible in our multi-verse."
We also know that Cameron plans to center the new film/trilogy around a new group of younger characters, who will eventually carry on the baton as it were.
"A lot of this is handing off the baton to a new generation of characters," Cameron said. "We're starting a search for an 18-something young woman to essentially be the new centerpiece of these stories. And then a number of other characters around her and characters from the future. We still fold time in the story in intriguing ways. But we have Arnold's character and Linda's character to anchor it."
How excited are you for James Cameron's new Terminator flick? Make sure to hit us up and let us know in the comments below or on social mdeia!
The new Terminator film is produced by James Cameron and will be directed by Tim Miller (Deadpool). The film stars Arnold Schwarzenegger and Linda Hamilton.
Terminator 2.5 is expected to hit July 26, 2019.
The Strangers: Prey at Night Official Site is Live and Waiting
It was just last week that we shared the all-new trailer and poster for the upcoming sequel to writer-director Bryan Bertino's home-invasion thriller The Strangers.
If that trailer for The Strangers: Prey at Night wasn't interactive enough for you then you're in luck – the film's official site has just gone live.
The site starts off playing the film's trailer but you can click that shite off asap and get to the other goodies.
From there the site tells you that "They're only Strangers until you tell them your name" and then asks you for your name, your email address, and your phone number.
Yeah. Right.
That's how they get you.
Truthfully, I'm not brave enough to put my info on the site. Not that I'm scared of, you know, a knock at the door late at night or anything… Just… I don't feel like it is all.
If you are brave enough to give the site your info, make sure to hit us up and let us know how it goes in the comments below or on social media! If you can… Moo-haha.
Visit the site HERE.
The Stranger: Prey at Night is directed by Johannes Roberts (47 Meters Down) from a script by Bryan Bertino and Ben Ketai. It stars Martin Henderson, Christina Hendricks, Bailee Madison, and Lewis Pullman.
The film hits March 9, 2018.
A family's road trip takes a dangerous turn when they arrive at a secluded mobile home park to stay with some relatives and find it mysteriously deserted. Under the cover of darkness, three masked psychopaths pay them a visit to test the family's every limit as they struggle to survive. Johannes Roberts directs this horror film inspired by the 2008 smash hit THE STRANGERS.
The Duffer Brothers Have Begun Working on Stranger Things 3
James Cameron's Terminator Reboot/Sequel Hires Screenwriter
The Strangers: Prey at Night Official Site is Live and Waiting
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Happy Record Store Day, fellow Choir members! Number 1 in line here at my local record store. Gonna be grabbing my special release vinyl and have another 20 or so other releases on my list to look into. Have a great day and a "Record Year," y'all!
Which Eric Church album produced his first two number one singles? Name the album and singles. First one to answer correctly will ask day 3 question.
Happy Thanksgiving to Eric and his family, ECB band and crew, ECHQ and of course to all of my fellow Church Choir members.
Reaching out to ya'll. After the Houston show was postponed until April, I can not access my ticket on my mobile phone anymore. I contacted Ticketmaster several times and they keep telling me they have sent me a new temp password. Checked spam/junk folders not there. Any one else having…
May we always be thankful for what we experience, what lies ahead and what we have right now...HAPPY THANKSGIVING
We may all agree to disagree.. :) Its all in fun.. First one to answer correctly with most votes on correct answer, will be correct and counted and goes on to ask a different question for day 2. My Day 1:
How many albums does the lyric "16th Avenue" in them?
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For anyone that is planning on being in Texas in April for the Church shows, myself and Aaron Shriver will be hosting a Church Choir party the night before the Houston show. If you are interested in attending this party please leave a comment with your name on Facebook and I will make sure…
In Search Of 10 year Sinner poster, WHITE Mr Misunderstood vinyl, Red Rocks Night 1 (left side) and Night 2 (right side) posters.
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Question about Harley Davidson Motorcycles
Posted by roguemike on
If you mean how to remove fuel line from the quick disconnect, pull up and hold the chrome collar while you twist and wiggle the fuel line off:
If you mean how to remove the fitting from the gas tank, it unscrews:
Posted on Feb 12, 2014
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Posted on Apr 25, 2009
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Recent Posts
- Italian film showing today: Se Dio vuole (Edoardo Falcone, 2015) 20/11/2017
- Next TNS seminar: 'On Cultural Transnationalisms: The case of World(-)literatures in Portuguese' 16/11/2017
- Italian film showing today: Smetto quando voglio – Masterclass (Sydney Sibilia, 2017) 13/11/2017
- Italian film showing today: Il bell'Antonio (Mauro Bolognini, 1960) 06/11/2017
- From Afrikaans and Albanian to Yoruba and Zulu – with a range of more commonly learnt languages in-between 03/11/2017
- CGE Research Seminar on 8th November: English as a Lingua Franca and language assessment: Challenges and opportunities 03/11/2017
- Italian film showing today: Che vuoi che sia / What's the Big Deal (Edoardo Leo, 2016) 30/10/2017
- Italian film showing today: L'Onorevole Angelina / Angelina (Luigi Zampa, 1947) 23/10/2017
- Next CLLEAR seminar: The effects of structured-input and structured-output tasks on the acquisition of English causative 17/10/2017
- Italian film showing today: La bella società (Gian Paolo Cugno, 2010) 16/10/2017
- Welcome to our University Open Day! 13/10/2017
- CGE Research Seminar today: Launching the Routledge Handbook of English as a Lingua Franca 11/10/2017
- New Italian film season starts today: Veloce come il vento (Matteo Rovere, 2016) 09/10/2017
- Become a Global Citizen – Learn a language at Southampton! 07/09/2017
- Try a language taster at our Lifelong Learning Taster Day 11/08/2017
- Modern Languages graduation today! 19/07/2017
- Southampton launches new EMI MOOC 26/06/2017
- Next TNS seminar: 'Linguistics, Ethnography and Identities' 16/06/2017
- Modern Languages and Linguistics to host Year 8 Able Linguist Days 05/06/2017
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Tag Archives: LLAS
Last chance to submit proposals for University of Southampton E-Learning Symposium 2015!
Do you make innovative use of technology in language teaching and learning? Have you been experimenting with MOOCs and wish to share your experiences? Do you use social networking sites, virtual worlds or mobile technology with your language students? Are you engaging students in the creation or use of open educational resources?
If so, don't miss this opportunity to submit your proposal for a presentation, workshop or poster for the 10th annual University of Southampton e-learning symposium, organised by the Centre for Language, Linguistics and Area Studies (LLAS), taking place on 22 and 23 January 2015. The deadline for submissions is Monday 13 October 2014.
For further details about the event and guidance on submissions, visit the LLAS website.
Welcome to visiting staff from the University of Aarhus!
This week, the English Language section together with LLAS in Modern Languagesare hosting a course in Professional English for a visiting group of teaching staff from the University of Aarhus in Denmark. The course is designed to increase participants' confidence and skill in delivering their teaching through the medium of English. Welcome to all our visitors from Aarhus. We hope you have a productive and enjoyable stay with us!
Presentations for Reshaping Languages in Higher Education conference now available
Following the highly successful Reshaping Languages in Higher Education conference, organised by the Centre for Languages Linguistics and Area Studies (LLAS), at the Grand Harbour Hotel, Southampton, earlier this month, a number of the presentation slides are now available online. To access these, visit the conference pages on the LLAS website.
LanguageBox: A resource for language teachers and students
Teachers and students of languages who wish to share and access teaching and learning materials online may be interested in LanguageBox, an open repository that allows storing, sharing and managing language learning resources, created by the University of Southampton. Language students can also find helpful learning resources. Over 30 languages are represented in LanguageBox.
LanguageBox is free for anyone to use. To find out more, visit the LanguageBox website.
Reshaping Languages in Higher Education Conference: A great success!
The two-day Reshaping Languages in Higher Education Conference run by LLAS at the Grand Harbour Hotel in Southampton last Wednesday and Thursday was a great success! Over 120 delegates attended a variety of presentations and exhibitions.
To catch up on some of the key points from the conference have a look at the history of the #LLASconf14 hashtag.
Date set for 10th University of Southampton e-learning symposium
The 10th University of Southampton e-learning symposium, organised by the Centre for Language, Linguistics and Area Studies (LLAS), will take place at the University of Southampton from 22-23 January 2015.
For updates on this event, keep an eye on the Languages at Southampton blog!
Reshaping Languages in Higher Education Conference 2014 – Early bird registration until 31st May
Anyone interested in attending the 'Reshaping Languages in Higher Education Conference 2014' can benefit from early bird registration until 31st May 2014. Read more…
English as a Medium for Administration (EMA) course delegate interviewed about her experiences
Monica Roth from Malmö University, Sweden, who attended the 'English as a Medium for Administration' (EMA) week-long course at the University of Southampton last month, has been interviewed about the role of English in her institution and her experiences at Southampton. Read more…
Teaching in higher education through the medium of English
A five-day course in 'Teaching in higher education through the medium of English' will be taking place at the University of Southampton from 9th – 13th June 2014. Read more…


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Dog Boarding in Larimer, Pittsburgh, PA
Find a loving dog sitter to watch your dog overnight at your sitter's home.
To ensure accurate availability & pricing, please add your drop-off and pick-up dates.Dismiss
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Quick Facts
Adult ADHD
Get the facts about attention deficit hyperactivity disorder (ADHD) in adults, including the different types and symptoms of each.
Care Guides
- Bipolar Disorder Facts about bipolar disorder, including different types and symptoms.
- ADHD Attention Deficit Hyperactivity Disorder (ADHD), including the different types and who gets them.
- Adult ADHD Facts about attention deficit hyperactivity disorder (ADHD) in adults.
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- Schizophrenia Facts about schizophrenia, including the different types.
- View All Care Guides Prepare for your next visit with our extensive library of Care Guides
About Dr. Thomas Crowley
Dr. Thomas Crowley, MD is a Doctor primarily located in Aurora, CO, with another office in Denver, CO. He has 51 years of experience. His specialties include Psychiatry. Dr. Crowley is affiliated with University Hospital - Denver and University Hospital - Denver. He speaks English.
Primary Address
12605 E 16th Ave
Aurora, CO 80045
Get Directions
Dr. Thomas Crowley has the following 1 specialty
- Psychiatry
A psychiatrist is a doctor with specific training in the diagnosis and treatment of mental illness.
He or she can not only provide the counseling necessary to both diagnose and treat a patient, but can also prescribe medication when...
17 Expertise
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Dr. Thomas Crowley is similar to the following 3 Doctors near Aurora, CO.
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- Bipolar Disorder
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- Sound: 10
- Overall Impression: 9
- Reliability & Durability: 10
- Action, Fit & Finish: 10
- Features: 9
Users' score:
(755 votes)
Sound — 10
This guitar can play anything you can imagine! First of all I use it with a Marshall which can guarantee you an amazing sound for all styles. Metal and rock are genres that this guitar absolutely nails! I don't know if it reaches the sound of a more expensive guitar, this is my first guitar, but it is very satisfying. The 5 choices you have over the pick-ups give you a vast variety of clean sounds. From the classic blues sound to funk and acoustic. Whatever music you like this guitar will play it up to its full potential!
Overall Impression — 9
This is perfect for metal/rock but good for every other genre. If I lost it I'd buy it again instead of getting something else. I love everything about it. The only bad thing about it is that when you tune it down (e.g. drop C, drop B etc) the other strings go up for some reason and it needs a little patience to tune all the strings (like 2-4 minutes). Other than that I'd say that this is a kick-a-s guitar!
Reliability & Durability — 10
I have only used this guitar live, twice and it didn't dissapoint me. I have bumped it on a desk a couple of times but never dropped it. Also there is no problem with the strap buttons what'soever. They are very big so it simply can't fall off when your playing live (or standing at home). This is definitely a guitar that you can depend on without a back up. I've had it for almost 1 year and it looks like I will have it for a very long time before I save up to get a better one. Its got lots to give you!
Action, Fit & Finish — 10
I got the guitar delivered just fine, no problem at all. It took about 8 days from the day I ordered it to the day it got to my house. Thomann is the best site to order anything to do with music. The box it came in had bags full of air (no damage whatsoever), and the guitar was tuned in standard tuning so its ready for action!
Features — 9
The Ibanex GRG170DX has 24 medium frets a rosewood fretboard, basswood body, and a maple neck. It has a very stylish Strat shape and the body is shiny and smooth. There are 3 pick-ups. One on the bridge, one on the neck and one in the middle. You can select different combinations of the pick-ups with a 5-way selector switch. There's also tone and volume knobs. When you buy it you will find a very nice gig bag (which has a lot of pockets) a strap, a cable about 2m long and some tools.


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I used to get this at Great China in Berkely, and am having a serious craving. It is a sort of cold noodle salad with cucumber, sea-cucumber, shrimp, pork etc. mixed in and a soy-sauce-mustard-based sauce. Any recs? Thanks!
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An MP's aide arrested over suspicions she has been spying for Russia has said she is "absolutely sure" she will win an appeal against deportation.
In her first public remarks, Katia Zatuliveter claimed she had been kept in the dark about why she was being kicked out of the UK.
Russian Miss Zatuliveter, 25, has been working for Liberal Democrat backbencher Mike Hancock for two-and-a-half years. She was arrested on Thursday morning and is being held at an immigration detention centre.
In an email to BBC Russian, Ms Zatuliveter said: "I was arrested on Thursday at 7am and was told I would be deported. Nobody explained me why and this is my main concern. I was not told about the arrangement of the flight. I am in the process of appealing against the deportation and absolutely sure I will win it (if there is justice)."
Meanwhile, two of Mr Hancock's constituents described the day Ms Zatuliveter showed them round the House of Commons on the MP's behalf.
Jon Coles, who visited Westminster last year with his wife Georgina, said the young woman was "highly intelligent" and "very charming".


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Got 10 freespins on Jimi Hendrix over a week ago and won and withdrew 25€ as that was the maximum allowed. Got a mail saying it would be processed within 48h. Checked a few days later and my history said it had been processed.
After waiting more than a week I contacted live support as I hadn't received my money. They claimed that I had to deposit money to get my withdrawal. I had already deposited 10€ before and the fs were only for depositing players from the start. Their bonus terms says nothing about this requirement.
Got 10 freespins on Jimi Hendrix over a week ago and won and withdrew 25€ as that was the maximum allowed. Got a mail saying it would be processed within 48h. Checked a few days later and my history said it had been processed.
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What Type of Ignition System is Best for a Gas Fireplace?
In many homes, there is a shift towards gas fireplaces since they do not require as much maintenance as wood-burning fireplaces. That said, some knowledge of their operation and maintenance is necessary. One of the most important features is the ignition system for the gas fireplace. Many older gas fireplaces have what is called […]Read More
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The chief reason for adding a fireplace to a home is to use it as a heat source, but there are some other good reasons for getting one. A fireplace can save money on home heating, create a romantic setting, and it helps to foster family togetherness. No wonder some homeowners can't seem to […]Read More
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Every homeowner has some sort of maintenance budget, no matter how modest. There will always be a few items that make the list every year, and money set aside to deal with these maintenance tasks. On the other hand, some people sometimes forget or sometimes ignore a few tasks that should be listed in the […]Read More
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How often do you think about your chimney? Is it only when you have a fire burning, or do you take the time to have maintenance completed on it at other times of the year? Well, your chimney is part of your home and it is definitely an item that needs to be maintained […]Read More
What Type of Flue Do You Need for Your Heat Producing Appliance?
Every homeowner knows that a home with a traditional chimney has a heat producing appliance of some time, and it's usually a fireplace or wood stove. What a lot of people don't realize is that their home probably has a few different types of flue. A flue, by definition, is a duct for smoke and […]Read More
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A 17.3% gain the Grain-Based Foods Share Index would be an impressive result in any year, but such strength in the industry's shares in 2012 was particularly remarkable, nearly to the point of being mystifying. Generally, in a stock market rally consumer staples may be expected to underperform the overall market as investors venture from the safer haven of industries like food.
The grain-based sector did not follow this pattern, besting the S.&P. 500, which was up 13% in 2012. What also may make this result somewhat surprising is that by many key measures, baking and other grain-based foods companies hardly had a banner year in 2012. Profit margins were under pressure as were sales volumes. Ingredient and other cost pressures were intense.
Major structural changes in wholesale baking create continued uncertainty about how the industry will take shape in the months and years ahead. So why the remarkable share strength? Because the stock market is a leading rather than a lagging economic indicator, the standout share price performance last year of baking and other grain-based companies should be viewed as a predictor of better times ahead. Last year's stock market offers a very hopeful sign for the industry's prospects going into 2013.
1Specialty Food Association names top trends in 2018
2McDonald's all-day breakfast gives Mile Hi a boost
3Alternative flours take another step into the mainstream
4Pipeline Foods breaks ground on North Dakota grain terminal
5Corporate social responsibility begins with employees
( more )
1How Amplify Snack Brands stays current in a competitive category
2Hearthside booming in Boise
3Kellogg to open expanded cereal cafe in Union Square
4Alternative flours take another step into the mainstream
5Clean up labels by ditching conventional mold inhibitors
1Three factors drive Kellogg sales decline
2Einstein Noah introduces new president and c.e.o.
3How Frito-Lay is making its products healthier
4Specialty Food Association names top trends in 2018
5Tips for eliminating bakery waste
to the PRINT edition, or click below for free INSTANT ACCESS to valuable news and insights in the Digital Edition.


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