text:
Research Topics
Genomes and Genes
Gene Symbol: ASGR2
Description: asialoglycoprotein receptor 2
Alias: ASGP-R2, ASGPR2, CLEC4H2, HBXBP, HL-2, asialoglycoprotein receptor 2, C-type lectin domain family 4 member H2, HBxAg-binding protein, hepatic lectin H2
Species: human
Top Publications
Research Grants
Scientific Experts
Detail Information
Publications131 found, 100 shown here
- A novel quality control compartment derived from the endoplasmic reticulumS Kamhi-Nesher
Department of Cell Research and Immunology, George Wise Faculty of Life Sciences, Tel Aviv University, Tel Aviv, Israel, 69978
Mol Biol Cell 12:1711-23. 2001....
- Mannose trimming is required for delivery of a glycoprotein from EDEM1 to XTP3-B and to late endoplasmic reticulum-associated degradation stepsBella Groisman
Department of Cell Research and Immunology, George Wise Faculty of Life Sciences, Tel Aviv University, Tel Aviv 69978, Israel
J Biol Chem 286:1292-300. 2011..Our results suggest that mannose trimming enables delivery of a substrate glycoprotein from EDEM1 to late ERAD steps through association with XTP3-B...
- Characteristics of three cases of hepatocellular carcinoma showing enhanced technetium-99m-diethylenetriaminepentaacetic acid-galactosyl human serum albumin accumulation by single photon emission computed tomography analysisAkihiko Suzuki
Department of Gastroenterology, Yamagata University Faculty of Medicine, Yamagata, Japan
Hepatol Res 37:628-36. 2007..ASGP-Roma is well-differentiated HCC, shows CT findings that are atypical of HCC, and is diagnosed by (99m)Tc-GSA SPECT analysis. We propose that ASGP-Roma be placed in a special category among well-differentiated HCC...
- Effects of hepatitis B virus S protein on human sperm functionXiao Ling Zhou
Research Center for Reproductive Medicine, Shantou University Medical College, Shantou 515041, People s Republic of China
Hum Reprod 24:1575-83. 2009..The purpose of this article was to investigate the effect of HBs on human sperm function...
- Gonococcal lipooligosaccharide is a ligand for the asialoglycoprotein receptor on human spermH A Harvey
Department of Microbiology, University of Iowa, Iowa City, IA 52242, USA Pediatric Infectious Disease Unit, Soroka University Medical Center, P O B 151, Beer Sheva, Israel
Mol Microbiol 36:1059-70. 2000..These data suggest that the ASGP-R on human sperm cells recognizes and binds wild-type gonococcal LOS. This interaction may contribute to the transmission of gonorrhea from infected males to their sexual partners...
- Three-dimensional models of the oligomeric human asialoglycoprotein receptor (ASGP-R)Ilaria Massarelli
UdR INSTM, Department of Pharmaceutical Sciences, University of Pisa, Via Bonanno 6, 56126 Pisa, Italy E mail
Int J Mol Sci 11:3867-84. 2010....
- Lactosaminated human albumin, a hepatotropic carrier of drugsLuigi Fiume
Department of Experimental Pathology, University of Bologna, Via San Giacomo 14, I 40126 Bologna, Italy
Eur J Pharm Sci 40:253-62. 2010....
- Preparation and biological evaluation of a glycosylated fusion interferon directed to hepatic receptorsGangming Cai
School of Medicine and Pharmaceutics, Jiangnan University, Wuxi, PR China
Biol Pharm Bull 32:440-3. 2009..53% and 6.66%, respectively (p < 0.01). Biodistribution research in mice showed that 125I-G-HSA-IFN could concentrate effectively in the liver (>45%/g) and suggested that it also could be a good imaging agent of hepatic receptors...
- Sendai virus efficiently infects cells via the asialoglycoprotein receptor and requires the presence of cleaved F0 precursor proteins for this alternative route of cell entryM Bitzer
Abteilung Innere Medizin I, Medizinische Universitätsklinik Tübingen, Germany
J Virol 71:5481-6. 1997..Interestingly, infection via ASGP-R was found to be nearly as efficient as infection via conventional sialic acid-containing SV receptors. A possible physiological role of the ASGP-R-mediated route of SV infection is discussed...
- Liver targeting liposomes containing beta-sitosterol glucoside with regard to penetration-enhancing effect on HepG2 cellsKumi Kawano
Institute of Medicinal Chemistry, Hoshi University, Tokyo, Japan
Biol Pharm Bull 25:766-70. 2002..The high degree of liver association of SG-liposomes in vivo might be related to recognition of glucose residues of SG by ASGP-R and to the high affinity and penetration-enhancing effect of Sit-G with hepatocytes...
- A novel hepatic-targeting system for therapeutic cytokines that delivers to the hepatic asialoglycoprotein receptor, but avoids receptor-mediated endocytosisHaruya Sato
Pharmaceutical Research Laboratories, Ajinomoto Co, Inc Suzuki cho, Kawasaki ku, 210 8681, Japan
Pharm Res 19:1736-44. 2002..To demonstrate the utilities of a synthetic low-affinity ligand ((Gal)3) for the asialoglycoprotein receptor (ASGP-R) as a hepatic targeting device for therapeutic cytokines...
- Metabolism of a novel nucleoside analogue, OGT 719, in the isolated perfused rat liver model, in rats, in tumour models and in patientsF Desmoulin
Biomedical NMR Group, UMR CNRS 5623, Universite Paul Sabatier, 118 route de Narbonne, 31062 Toulouse, France
Xenobiotica 33:289-303. 2003..6. The metabolism of OGT 719 was also extremely low in patients. 7. In conclusion, the present study shows the value of (19)F-NMR for demonstrating for the first time that OGT 719 is a prodrug of FU although very poorly metabolized...
- Monitoring biodistribution of glycoproteins with modified sugar chainsShinji Takamatsu
Biomedical Imaging Research Center, Fukui Medical University, 23 3 Matsuoka, Yoshida, Fukui 910 1193, Japan
Biochim Biophys Acta 1622:179-91. 2003..Our observation is not the same as the "glycoside cluster effect." We thus provide important information on the character of modified recombinant glycoproteins...
- An internalizing antibody specific for the human asialoglycoprotein receptorAlla Trahtenherts
Department of Molecular Microbiology and Biotechnology, The George S Wise Faculty of Life Sciences, Tel Aviv University, Ramat Aviv, Israel
Hybridoma (Larchmt) 28:225-33. 2009..Thus, this newly isolated antibody can serve as a targeting moiety for ASGPR-directed drug delivery...
- Molecular imaging contrast media for visualization of liver functionMatsuoka Yoshinori
Department of Disaster and Emergency Medicine, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Kyushu, Japan
Magn Reson Imaging 28:708-15. 2010..The aims of this study are to develop new contrast media for visualization of functional changes in the liver and to check the effectiveness of the media...
- Comparative in silico-in vivo evaluation of ASGP-R ligands for hepatic targeting of curcumin Gantrez nanoparticlesAnisha A D'Souza
Department of Pharmaceutical Sciences and Technology, Institute of Chemical Technology Deemed University, N P Marg, Matunga, Mumbai, 400019, India
AAPS J 15:696-706. 2013..Docking analysis provides a useful tool for the preliminary screening of ligands for hepatic targeting...
- Galactosylated poly(ethylene glycol) methacrylate-st-3-guanidinopropyl methacrylamide copolymers as siRNA carriers for inhibiting Survivin expression in vitro and in vivoYang Wu
Biomaterials and Drug Delivery Laboratories, School of Chemistry and Chemical Engineering, Southeast University, Nanjing, P R China
J Drug Target 22:352-64. 2014..Furthermore, Survivin siRNA/GGP polyplexes could significantly (p < 0.01) inhibit both HepG2 tumor growth and Survivin protein expression in vivo studies in a xenograft mouse model...
- Polyvalent display of monosaccharides on ferritin protein cage nanoparticles for the recognition and binding of cell-surface lectinsYoung Ji Kang
School of Nano Bioscience and Chemical Engineering, Ulsan National Institute of Science and Technology UNIST, Ulsan, 689 798, Korea
Macromol Biosci 14:619-25. 2014..Mannose- or galactose-displaying HFPCNs recognize and tightly bind to DC-SIGN or ASGP-R lectins on the surface of the mammalian cells, DCEK or HepG2 cells. ..
- Reductively degradable α-amino acid-based poly(ester amide)-graft-galactose copolymers: facile synthesis, self-assembly, and hepatoma-targeting doxorubicin deliveryJiaolong Lv
Biomedical Polymers Laboratory, and Jiangsu Key Laboratory of Advanced Functional Polymer Design and Application, College of Chemistry, Chemical Engineering and Materials Science, Soochow University, Suzhou, 215123, P R China
Biomater Sci 3:1134-46. 2015..0 mg mL(-1). These tumor-targeting and reduction-responsive degradable nanoparticles have appeared as an interesting multi-functional platform for advanced drug delivery. ..
- Simplified quantification method for in vivo SPECT/CT imaging of asialoglycoprotein receptor with (99m)Tc-p(VLA-co-VNI) to assess and stage hepatic fibrosis in miceDeliang Zhang
Center for Molecular Imaging and Translational Medicine, State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics, School of Public Health, Xiamen University, Xiamen 361102, China
Sci Rep 6:25377. 2016..83) as well as LUV and Sirius Red quantification (r = -0.83). In conclusion, SPECT imaging with (99m)Tc-p(VLA-co-VNI) is useful in evaluating and staging liver fibrosis in vivo. ..
- Functional Consequences of Mannose and Asialoglycoprotein Receptor AblationYiling Mi
From the Department of Biochemistry and Molecular Biophysics, Washington University School of Medicine, St Louis, Missouri 63110
J Biol Chem 291:18700-17. 2016The mannose receptor (ManR, Mrc1) and asialoglycoprotein receptor (ASGR, Asgr1 and Asgr2) are highly abundant endocytic receptors expressed by sinusoidal endothelial cells and parenchymal cells in the liver, respectively...
- Rapid clearance of sialylated glycoproteins by the asialoglycoprotein receptorEric I Park
Department of Pathology, School of Medicine, Washington University, St Louis, Missouri 63110, USA
J Biol Chem 278:4597-602. 2003....
- Liver-targeted doxorubicin: effects on rat regenerating hepatocytesGiuseppina Di Stefano
Department of Experimental Pathology, University of Bologna, Via San Giacomo, Bologna, Italy
Liver Int 24:246-52. 2004....
- Ultrastructural analysis of the pathogenesis of Neisseria gonorrhoeae endometrial infectionMichelle M Timmerman
The University of Iowa, Department of Microbiology, Iowa City, 52242, USA
Cell Microbiol 7:627-36. 2005..This diversity is consistent with a role of the endometrium as a transition zone between frequently asymptomatic cervical gonorrhoea and symptomatic pelvic inflammatory disease...
- Galactosylated polyethylenimine-graft-poly(vinyl pyrrolidone) as a hepatocyte-targeting gene carrierSeung Eun Cook
School of Agricultural Biotechnology, Seoul National University, Seoul 151 742, South Korea
J Control Release 105:151-63. 2005..And GPP/DNA complexes were mediated by asialoglycoprotein receptors (ASGP-R)-mediated endocytosis. Also, the transfection efficiency of GPP-1/DNA complex at charge ratio of 40 in the HepG2 was higher than that of PEI/DNA one...
- A new N-acetylgalactosamine containing peptide as a targeting vehicle for mammalian hepatocytes via asialoglycoprotein receptor endocytosisYing Ta Wu
Institute of Biological Chemistry, Academia Sinica, Taipei 115, Taiwan
Curr Drug Deliv 1:119-27. 2004....
- Targeting of lanthanide(III) chelates of DOTA-type glycoconjugates to the hepatic asyaloglycoprotein receptor: cell internalization and animal imaging studiesM I M Prata
Instituto de Biofísica e Biomatemática, Faculdade de Medicina, Universidade de Coimbra, Coimbra, Portugal
Contrast Media Mol Imaging 1:246-58. 2006..This probably results from the quick wash-out from the liver of these highly hydrophilic complexes, before they can be sufficiently concentrated within the hepatocytes via receptor-mediated endocytosis...
- Microtubule acetylation and stability may explain alcohol-induced alterations in hepatic protein traffickingRohan A Joseph
Department of Biology, The Catholic University of America, Washington, DC 20064, USA
Hepatology 47:1745-53. 2008..We further determined that albumin secretion was impaired in both ethanol-treated and TSA-treated cells, indicating that increased microtubule acetylation and stability also disrupted this transport step...
- Impaired receptor-mediated endocytosis: its role in alcohol-induced apoptosisCarol A Casey
Department of Veterans Affairs Medical Center, University of Nebraska Medical Center, Omaha, Nebraska 68105, USA
J Gastroenterol Hepatol 23:S46-9. 2008..The goal of our future work is to show that inadequate removal of apoptotic cells, in part via altered receptor-mediated endocytosis, plays a role in the course of pathogenesis of alcoholic liver injury...
- Hepatocyte cytotoxicity is facilitated by asialoglycoprotein receptorClifford S Guy
Molecular Virology and Hepatology Research Group, Division of Biomedical Sciences, Faculty of Medicine, Health Sciences Centre, Memorial University, St John s, Newfoundland, Canada
Hepatology 54:1043-50. 2011....
- Bypass of glycan-dependent glycoprotein delivery to ERAD by up-regulated EDEM1Efrat Ron
Department of Cell Research and Immunology, George Wise Faculty of Life Sciences, Tel Aviv University, Tel Aviv 69978, Israel
Mol Biol Cell 22:3945-54. 2011..At high EDEM1 levels, glycoprotein release is prevented and glycan interactions are no longer required, canceling the otherwise mandatory ERAD timing by mannose trimming and accelerating the targeting to degradation...
- In vivo hepatocyte MR imaging using lactose functionalized magnetoliposomesAshwini Ketkar-Atre
Biomedical MRI MoSAIC, Department of Imaging and Pathology, Biomedical Sciences Group, Katholieke Universiteit Leuven, Herestraat 49, B3000 Leuven, Belgium
Biomaterials 35:1015-24. 2014..These data demonstrate that galactose-functionalized MLs can be used as a hepatocyte targeting MR contrast agent to potentially aid in the diagnosis of hepatic diseases if the non-specific uptake by KCs is taken into account...
- Glyco-nanoparticles with sheddable saccharide shells: a unique and potent platform for hepatoma-targeting delivery of anticancer drugsWei Chen
Biomedical Polymers Laboratory, and Jiangsu Key Laboratory of Advanced Functional Polymer Design and Application, Department of Polymer Science and Engineering, College of Chemistry, Chemical Engineering and Materials Science, Soochow University, Suzhou, 215123, People s Republic of China
Biomacromolecules 15:900-7. 2014..0 mg/mL. These shell-sheddable glyco-nanoparticles are promising for hepatoma-targeting chemotherapy. ..
- Recent advances in active hepatic targeting drug delivery systemYang Wang
Department of Pharmaceutics, College of Pharmacy, Shandong University, 44 Wenhua Xilu, Jinan 250012, China
Curr Drug Targets 15:573-99. 2014....
- Kit formulated asialoglycoprotein receptor targeting tracer based on copolymer for liver SPECT imagingChang Liu
Key Laboratory of Radiopharmaceuticals, Ministry of Education, College of Chemistry, Beijing Normal University, Beijing, 100875, China Electronic address
Nucl Med Biol 41:587-93. 2014..In this study, galactosyl polystyrene was synthesized from controllable ratio of functional monomers and radio-labelled with (99m)Tc by formulated kit for SPECT imaging of hepatic function...
- Galactose-installed photo-crosslinked pH-sensitive degradable micelles for active targeting chemotherapy of hepatocellular carcinoma in miceYan Zou
Biomedical Polymers Laboratory, and Jiangsu Key Laboratory of Advanced Functional Polymer Design and Application, College of Chemistry, Chemical Engineering and Materials Science, Soochow University, Suzhou 215123, China
J Control Release 193:154-61. 2014..Ligand-installed photo-crosslinked pH-responsive degradable micelles have a great potential for targeted cancer chemotherapy...
- Intracellular redox-activated anticancer drug delivery by functionalized hollow mesoporous silica nanoreservoirs with tumor specificityZhong Luo
Key Laboratory of Biorheological Science and Technology, Ministry of Education, College of Bioengineering, Chongqing University, Chongqing 400044, PR China Division of Chemistry and Biological Chemistry, School of Physical and Mathematical Sciences, Nanyang Technological University, 21 Nanyang Link, Singapore 637371, Singapore
Biomaterials 35:7951-62. 2014..On the whole, this drug delivery system exhibits a great potential as an efficient carrier for targeted tumor therapy in vitro and in vivo. ..
- Increased gene delivery efficiency and specificity of a lipid-based nanosystem incorporating a glycolipidMariana Magalhães
Center for Neuroscience and Cell Biology, University of Coimbra, Coimbra, Portugal Department of Life Sciences, Faculty of Science and Technology, University of Coimbra, Coimbra, Portugal
Int J Nanomedicine 9:4979-89. 2014....
- Stealth lipoplex decorated with triazole-tethered galactosyl moieties: a strong hepatotropic gene vectorDhineshree Govender
Non Viral Gene Delivery Laboratory, Discipline of Biochemistry, University of KwaZulu Natal, Durban, South Africa
Biotechnol Lett 37:567-75. 2015..Transfection activities achieved in HEK293 cells were up to three orders of magnitude lower. Therefore, 4 is representative of a new class of promising hepatotropic ligands for gene delivery...
- Biofabricated nanoparticle coating for liver-cell targetingCheng Zhang
The State Key Laboratory of Bioreactor Engineering, East China University of Science and Technology, Shanghai, 200237, China
Adv Healthc Mater 4:1972-81. 2015..These studies extend the use of Con A to sugar-mediated and organ-specific targeting, and further illustrate the potential of biologically based fabrication for generating functional materials. ..
- Absorption and blood/cellular transport of folate and cobalamin: Pharmacokinetic and physiological considerationsDavid H Alpers
Department of Internal Medicine, Washington University School of Medicine, St Louis, MO 63130, USA Electronic address
Biochimie 126:52-6. 2016..These complexities help to explain the variable clinical responses after oral administration of the vitamins, especially when provided as supplements. ..
- Asialoglycoprotein receptor facilitates infection of PLC/PRF/5 cells by HEV through interaction with ORF2Li Zhang
Division of HIV AIDS and Sexually Transmitted Virus Vaccines, National Institutes for Food and Drug Control, Beijing, China
J Med Virol 88:2186-2195. 2016..and ELISA were used to show that the HEV ORF2 protein interacts directly with the ectodomain of both ASGR1 and ASGR2. Susceptibility to HEV correlated positively with the expression level of surface asialoglycoprotein receptor (..
- Well-Defined Multivalent Ligands for Hepatocytes Targeting via Asialoglycoprotein ReceptorXiangang Huang
Institute of Pharmaceutical Sciences, Department of Chemistry and Applied Biosciences, ETH Zurich, Vladimir Prelog Weg 1 5 10, 8093 Zurich, Switzerland
Bioconjug Chem . 2016..The present manuscript provides important guidelines for the design of multivalent ligands for ASGP-R...
- The effect of ethanol on asialoglycoprotein receptor-mediated phagocytosis of apoptotic cells by rat hepatocytesBenita L McVicker
Liver Study Unit, Department of Veterans Affairs Medical Center, Department of Internal Medicine, University of Nebraska Medical Center, Omaha, NE, USA
Hepatology 36:1478-87. 2002....
- Closely related mammals have distinct asialoglycoprotein receptor carbohydrate specificitiesEric I Park
Department of Pathology, Washington University School of Medicine, St Louis, Missouri 63110, USA
J Biol Chem 279:40954-9. 2004..We hypothesize that the altered specificity of ASPG-R orthologues in such evolutionarily closely related species reflects rapidly changing requirements for recognition of endogenous or exogenous oligosaccharides in vivo...
- Hepatocyte-targeted nuclear imaging using 99mTc-galactosylated chitosan: conjugation, targeting, and biodistributionEun Mi Kim
Department of Nuclear Medicine, Wonkwang University School of Medicine, 344 2 Sinyong dong, Iskan, Jellabuk Do, 570 711, Korea
J Nucl Med 46:141-5. 2005..The aim of this study was to investigate the possibility of liver-targeted nuclear imaging with (99m)Tc-GMC bound to asialoglycoprotein receptors (ASGP-R)...
- Enhanced uptake of lactosaminated human albumin by rat hepatocarcinomas: implications for an improved chemotherapy of primary liver tumorsGiuseppina Di Stefano
Department of Experimental Pathology, University of Bologna, Italy
Liver Int 25:854-60. 2005..The aim of the present experiments was to ascertain whether ASGP-R of HCCs is functionally active and these tumors can internalize higher quantities of MEGRs than extra-hepatic tissues...
- Role of E-cadherin molecules in spheroid formation of hepatocytes adhered on galactose-carrying polymer as an artificial asialoglycoprotein modelR Takei
Department of Biomolecular Engineering, Tokyo Institute of Technology, 226 8501, Yokohama, Japan
Biotechnol Lett 27:1149-56. 2005..As a result, E-cadherin could play an important role in hepatocyte assembly...
- Feasibility on systemic delivery of asialoorosomucoid complex to hepatic origin cells mediated by asialoglycoprotein receptorSun Jun
Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
J Huazhong Univ Sci Technolog Med Sci 25:234-5, 239. 2005..This research testified the feasibility of targeting Asor complex delivery to hepatocyte mediated by ASGP-R in vivo, and provided foundation for the genetic diagnosis and gene therapy of hepatic cell-related diseases...
- A secreted form of the asialoglycoprotein receptor, sH2a, as a novel potential noninvasive marker for liver fibrosisElena Veselkin
Department of Cell Research and Immunology, George Wise Faculty of Life Sciences, Tel Aviv University, Tel Aviv, Israel
PLoS ONE 6:e27210. 2011..Here we determined and report that sH2a, present at constant levels in serum from healthy individuals is altered upon liver fibrosis, reflecting the status of hepatocyte function...
- Potential use of lactosylated dendrimer (G3)/α-cyclodextrin conjugates as hepatocyte-specific siRNA carriers for the treatment of familial amyloidotic polyneuropathyYuya Hayashi
Department of Physical Pharmaceutics, Graduate School of Pharmaceutical Sciences, Kumamoto University, 5 1 Oe honmachi, Kumamoto 862 0973, Japan
Mol Pharm 9:1645-53. 2012..Taken together, these results suggest that Lac-α-CDE (G3, DSL 1.2) has the potential for a novel hepatocyte-selective siRNA carrier in vitro and in vivo, and has a possibility as a therapeutic tool for FAP to the liver transplantation...
- NMR study of ligand release from asialoglycoprotein receptor under solution conditions in early endosomesTakuo Onizuka
Research and Development Department, Japan Biological Informatics Consortium, Tokyo, Japan
FEBS J 279:2645-56. 2012..In our proposed mechanism, ASGP-R can rapidly release Ca(2+) and its ligand even at nearly neutral pH. Sequence comparisons of endocytic C-type lectin receptors suggest that this mechanism is common in their family...
- Efficacious hepatoma-targeted nanomedicine self-assembled from galactopeptide and doxorubicin driven by two-stage physical interactionsJianxun Ding
Key Laboratory of Polymer Ecomaterials, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun 130022, PR China
J Control Release 169:193-203. 2013..The above superiorities indicated that the galactosylated nanomedicine possessed great promising for hepatoma-targeted chemotherapy...
- DNA nanocarriers for systemic administration: characterization and in vivo bioimaging in healthy miceStephanie David
1 LUNAM Université d Angers, Angers, France 2 INSERM U1066, Micro et Nanomedecines biomimétiques, Angers, France 3 INSERM UMR1087 Université de Nantes, Nantes, France
Mol Ther Nucleic Acids 2:e64. 2013..Molecular Therapy - Nucleic Acids (2013) 2, e64; doi:10.1038/mtna.2012.56; published online 8 January 2013...
- Glycosylated liposomes with proton sponge capacity: novel hepatocyte- specific gene carriersSaffiya Habib
Discipline of Biochemistry, University of KwaZulu Natal, P Bag X54001, Durban 4000, South Africa
Curr Drug Deliv 10:685-95. 2013..001). Therefore the combination of Chol-LAC and Chol- UAC in cationic liposomal formulations may provide a platform for the development of useful hepatotropic gene delivery systems. ..
- Liver-targeting of primaquine-(poly-γ-glutamic acid) and its degradation in rat hepatocytesNoboru Tomiya
Department of Biology, Johns Hopkins University, Baltimore, MD 21218, USA
Bioorg Med Chem 21:5275-81. 2013....
- Ligand-directed reduction-sensitive shell-sheddable biodegradable micelles actively deliver doxorubicin into the nuclei of target cancer cellsYinan Zhong
Biomedical Polymers Laboratory and Jiangsu Key Laboratory of Advanced Functional Polymer Design and Application, College of Chemistry, Chemical Engineering and Materials Science, Soochow University, Suzhou, 215123, People s Republic of China
Biomacromolecules 14:3723-30. 2013..Ligand-directed, reduction-sensitive, shell-sheddable, and biodegradable micelles have emerged as a versatile and potent platform for targeted cancer chemotherapy. ..
- Galactose-functionalized cationic polycarbonate diblock copolymer for targeted gene delivery to hepatocytesZhan Yuin Ong
Institute of Bioengineering and Nanotechnology, 31 Biopolis Way, Singapore, 138669, Singapore
Macromol Rapid Commun 34:1714-20. 2013..Taken together, the galactose-functionalized cationic polycarbonate diblock copolymer has potential for use as a non-viral gene vector for the targeted delivery of therapeutic genes to hepatocytes in the treatment of liver diseases. ..
- Asialoglycoprotein receptor concentration in tumor-bearing livers and its fate early after their sectorial resectionXiao Feng Li
Department of Biotracer Medicine, Kanazawa University Graduate School of Medical Sciences, Japan
Ann Nucl Med 17:489-93. 2003..The aim of the present study was to investigate asialoglycoprotein receptor (ASGP-R) status in tumor-bearing livers and early after their sectorial resection employing 99mTc-DTPA-galactosyl human serum albumin (99mTc-GSA) dynamic SPECT...
- IGF-1 induces growth, survival and morphological change of primary hepatocytes on a galactose-bared polymer through both MAPK and beta-catenin pathwaysAnup Kumer Kundu
Department of Biomolecular Engineering, Graduate School of Bioscience and Biotechnology, Tokyo Institute of Technology, Yokohama, Japan
Cell Struct Funct 28:255-63. 2003....
- Receptor-mediated endocytosis by the asialoglycoprotein receptor: effect of ethanol administration on endosomal distribution of receptor and ligandShana R Dalton
Department of Internal Medicine, University of Nebraska Medical Center, Omaha, NE 68198 2000, USA
Liver Int 23:484-91. 2003..These results suggest that delayed dissociation may cause the receptor ligand complexes to travel farther into the cell interior, which may impair proper trafficking of the ligand to lysosomes and alter the receptor recycling...
- Heterogeneity of expression of IgA receptors by human, mouse, and rat eosinophilsVéronique Decot
Institut National de la Santé et de la Recherche Médicale Unité 547 Institut Fédératif de Recherche 17, Institut Pasteur de Lille, France
J Immunol 174:628-35. 2005..Indeed, mouse eosinophils expressed only TfR, whereas rat eosinophils expressed ASGP-R and CD89 mRNA. These results provide a molecular basis for the differences observed between human, rat, and mouse regarding IgA-mediated immunity...
- Asialoglycoprotein receptor targeted gene delivery using galactosylated polyethylenimine-graft-poly(ethylene glycol): in vitro and in vivo studiesEun Mi Kim
Department of Nuclear Medicine, Research Institute of Clinical Medicine, Chonbuk National University School of Medicine, Jeonju, Jeonbuk, Korea
J Control Release 108:557-67. 2005..The GPP(50)/DNA complexes were bound to ASGP-R of the proliferating hepatocytes in vitro and in vivo. The present results demonstrate the feasibility of nonviral gene transfer using galactosylated PEI-PEG in vivo...
- Synthesis and evaluation of a photoactive probe with a multivalent carbohydrate for capturing carbohydrate-lectin interactionsTsung Che Chang
Department of Chemistry and
Bioconjug Chem 24:1895-906. 2013..coli lysate and an asialoglycoprotein receptor (ASGP-R) on intact HepG2 cell membranes. Moreover, the probe also enabled the detection of weak protein-protein interactions between RCA120 and ovalbumin (OVA). ..
- Differences in the abundance of variably spliced transcripts for the second asialoglycoprotein receptor polypeptide, H2, in normal and transformed human liverE Paietta
Department of Oncology, Montefiore Medical Center, Bronx, New York 10467
Hepatology 15:395-402. 1992....
- Alternatively spliced variants of the human hepatic asialoglycoprotein receptor, H2, differ in cellular trafficking and regulation of phosphorylationE Paietta
Department of Oncology, Montefiore Medical Center, Bronx, New York 10467
J Biol Chem 267:11078-84. 1992..Since the 57-nucleotide region does not encode for serine residues, it per se cannot be the site of phosphorylation but rather constitutes a regulatory element for post-translational modification...
- Endocytosis by the asialoglycoprotein receptor is independent of cytoplasmic serine residuesI Geffen
Department of Biochemistry, University of Basel, Switzerland
Proc Natl Acad Sci U S A 88:8425-9. 1991..Analysis of individual serine mutations identified serine-12 of subunit H2 as the major site of phosphorylation in the ASGP receptor...
- Sequence of a second human asialoglycoprotein receptor: conservation of two receptor genes during evolutionM Spiess
Proc Natl Acad Sci U S A 82:6465-9. 1985..005-0.01% of the total mRNA. This finding raises the question of whether the three ASGP receptor proteins are functional as heterodimers or whether they might serve different functions in the cell...
- Detection and quantification of soluble asialoglycoprotein receptor in human serumH Yago
Fourth Department of Internal Medicine, Sapporo Medical University School of Medicine, Japan
Hepatology 21:383-8. 1995..The detection limit was estimated to be 0.1 micrograms/L. By nonparametolic analysis, a median and a 90% tile of serum AGPR level obtained from 283 normal volunteers were 0.4 micrograms/L and 2.4 micrograms/L, respectively...
- The asialoglycoprotein receptor is a potential liver-specific receptor for Marburg virusS Becker
Institut fur Virologie, Philipps Universitat Marburg, Germany
J Gen Virol 76:393-9. 1995..5-fold. Interaction of MBG with the hepatic ASGP-R could thus explain the marked hepatotropism of the virus...
- The major form of the murine asialoglycoprotein receptor: cDNA sequence and expression in liver, testis and epididymisR S Monroe
Wellcome Research Laboratories, Research Triangle Park, NC 27709
Gene 148:237-44. 1994..Taken collectively, these data describe the cloning and sequencing of the MHL-1 cDNA and illustrate its deduced aa homology to RHL-1 and H1.(ABSTRACT TRUNCATED AT 250 WORDS)..
- The secretory pathway is normal in dithiothreitol-treated cells, but disulfide-bonded proteins are reduced and reversibly retained in the endoplasmic reticulumH F Lodish
Whitehead Institute for Biomedical Research, Cambridge, Massachusetts 02142
J Biol Chem 268:20598-605. 1993....
- Receptor-mediated entry of hepatitis B virus particles into liver cellsU Treichel
Department of Internal Medicine, Johannes Gutenberg University Mainz, Federal Republic of Germany
Arch Virol 142:493-8. 1997..These results suggest that the ASGPR is capable of specifically binding HBV-particles and, moreover, to mediate their hepatic endocytosis which ultimately could be responsible for the HBV-infection of liver cells...
- A novel, orally administered nucleoside analogue, OGT 719, inhibits the liver invasive growth of a human colorectal tumor, C170HM2C Rohlff
Oxford GlycoSciences, Abingdon, United Kingdom
Cancer Res 59:1268-72. 1999..This hypothesis is presently being explored in clinical trials for primary hepatocellular carcinoma and colorectal liver metastases...
- Evaluation of asialoglycoprotein receptor imaging agent as a marker of hepatic ischemia-reperfusion injury and recoveryH Toyama
Department of Radiology, Fujita Health University, Toyoake, Aichi, Japan
Ann Nucl Med 13:155-60. 1999..ASGP-R binding may provide valuable information on ischemia-reperfusion injury and recovery...
- The asialoglycoprotein receptor in human hepatocellular carcinomas: its expression on proliferating cellsD Trere
Servizio di Citopatologia, Policlinico S Orsola, and Dipartimento di Patologia Sperimentale, Universita di Bologna, Italy
Br J Cancer 81:404-8. 1999....
- The N-glycans determine the differential blood clearance and hepatic uptake of human immunoglobulin (Ig)A1 and IgA2 isotypesA Rifai
Department of Pathology, Rhode Island Hospital, Brown University, Providence, Rhode Island 02903, USA
J Exp Med 191:2171-82. 2000..In addition, dysfunction of the ASGR or altered N-linked glycosylation, but not O-glycans, that affects recognition by this receptor may account for the elevated serum IgA seen in liver disease and IgA nephropathy...
- A 3D model for the human hepatic asialoglycoprotein receptor (ASGP-R)A M Bianucci
Dipartimento di Scienze Farmaceutiche, Universita di Pisa, Italy
J Biomol Struct Dyn 18:435-51. 2000..The new modeling procedure used here appears to be a well-suited method for structural analysis of small regions, located around the ligands, in proteins of unknown 3D structure...
- Efficiency of liposomes surface-modified with soybean-derived sterylglucoside as a liver targeting carrier in HepG2 cellsY Maitani
Department of Pharmaceutics, Hoshi University, Ebara 2 4 41, Shinagawa ku, 142 8501, Tokyo, Japan
J Control Release 75:381-9. 2001..SG-liposomes are potentially useful drug carriers to the liver, because the glucose residue may work as a kind of ligand for ASGP-R...
- Cloning, mapping, and characterization of a human homologue of the yeast longevity assurance gene LAG1H Pan
State Key Laboratory of Genetic Engineering, Institute of Genetics, School of Life Science, Fudan University, Shanghai 200433, China
Genomics 77:58-64. 2001..Furthermore, LASS2 protein was able to inhibit the colony formation of human hepatoma cells in vitro, which suggests that this gene may be involved in the regulation of cell growth...
- Targeting hepatocytes for drug and gene delivery: emerging novel approaches and applicationsJian Wu
Transplant Research Institute, University of California, Davis Medical Center, Sacramento, CA 95817, USA
Front Biosci 7:d717-25. 2002..Finally, galactosylated polymers are promising for gene delivery, but require further studies to verify their potential applications...
- H2, the minor subunit of the human asialoglycoprotein receptor, trafficks intracellularly and forms homo-oligomers, but does not bind asialo-orosomucoidAmit Saxena
Department of Biochemistry and Molecular Biology, and The Oklahoma Center for Medical Glycobiology, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma 73190, USA
J Biol Chem 277:35297-304. 2002..Nonetheless, these results raise the intriguing possibility that naturally occurring H2 homo-oligomers may exist in human hepatocytes and have an as yet undiscovered function...
- Interactions of human mesangial cells with IgA and IgA-containing immune complexesJan Novak
Department of Microbiology, University of Alabama at Birmingham, Birmingham, Alabama 35294, USA
Kidney Int 62:465-75. 2002..The circulating immune complexes (CIC) are composed of galactose- (Gal) deficient IgA1 and IgG or IgA1 antibodies specific for the Gal-deficient IgA1; interactions of these CIC with mesangial cells (MC) were studied...
- Expression of a functional asialoglycoprotein receptor in human renal proximal tubular epithelial cellsYing ying T Seow
Department of Renal Medicine, Singapore General Hospital, Singapore, Republic of Singapore
Nephron 91:431-8. 2002..In the kidney, there has been evidence both for and against its existence in mesangial cells...
- Predictors of successful hepatic resection: prognostic usefulness of hepatic asialoglycoprotein receptor analysisNorihiro Kokudo
Department of Surgery, Cancer Institute Hospital, 1 37 1 Kami Ikebukuro, Toshima ku, Tokyo, Japan 170 8455
World J Surg 26:1342-7. 2002..Cirrhotic patients and patients with a low R0-remnant are at higher risk for postoperative liver failure. The present study confirms the usefulness of hepatic asialogycoprotein receptor analysis in liver surgery...
- Palmitoylation-defective asialoglycoprotein receptors are normal in their cellular distribution and ability to bind ligand, but are defective in ligand uptake and degradationJasper H N Yik
Department of Biochemistry and Molecular Biology, Oklahoma Center for Medical Glycobiology, University of Oklahoma Health Sciences Center, Oklahoma City, OK 73190, USA
Biochem Biophys Res Commun 297:980-6. 2002..We conclude that failure to palmitoylate Cys residues in either or both subunits of human ASGP-Rs results in very inefficient uptake and degradation of ligands...
- The position of cysteine relative to the transmembrane domain is critical for palmitoylation of H1, the major subunit of the human asialoglycoprotein receptorJasper H N Yik
Department of Biochemistry and Molecular Biology and the Oklahoma Center for Medical Glycobiology, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma 73190, USA
J Biol Chem 277:47305-12. 2002..We conclude that the spacing of a Cys residue relative to the TMD in the primary protein sequence of H1 is the major determinant for successful palmitoylation...
- Role of the asialoglycoprotein receptor in binding and entry of hepatitis C virus structural proteins in cultured human hepatocytesBertrand Saunier
Edison Biotechnology Institute and College of Osteopathic Medicine, Ohio University, Athens 45701, USA
J Virol 77:546-59. 2003..Our observations suggest that HCV structural proteins bind to and cointernalize with the ASGP-R in cultured human hepatocytes...
- [Study on the hepatocytic cell targetability of liposomes]Xin pu Hou
Department of Pharmaceutics, School of Pharmacy, Peking University, Beijing 100083, China
Yao Xue Xue Bao 38:143-6. 2003..To target for hepatocytic cell, liposomes was modified by special ligand...
- Liver asialoglycoprotein receptor levels correlate with severity of alcoholic liver damage in ratsCarol A Casey
Liver Study Unit, Department of Internal Medicine and Biochemistry and Molecular Biology, University of Nebraska Medical Center, Omaha NE 68198, USA
J Appl Physiol (1985) 96:76-80. 2004..These results demonstrate that a correlation exists between the progression of alcohol-associated liver injury, as defined by the severity of liver pathology, and an ethanol-induced decline in ASGP-R content...
- Clinical application of TcGSANorihiro Kokudo
Department of Surgery, University of Tokyo, Tokyo 113 8655, Japan
Nucl Med Biol 30:845-9. 2003..Considering the moderate cost and widespread availability of gamma cameras, a TcGSA test should be performed on patients whose liver function are not adequately estimated by an ICG test or a Child-Turcotte score...
- Asialoglycoprotein receptor facilitates hemolysis in patients with alcoholic liver cirrhosisPhilip Hilgard
University Hospital Essen, Department for Gastroenterology and Hepatology, Essen, Germany
Hepatology 39:1398-407. 2004....
- Cellular disposition of arabinogalactan in primary cultured rat hepatocytesTetsuro Tanaka
Department of Biopharmaceutics, Faculty of Pharmacy and Pharmaceutical Sciences, Fukuyama University, Sanzo, Gakuen cho, Fukuyama, Hiroshima 729 0292, Japan
Eur J Pharm Sci 22:435-44. 2004....
- [Preliminary study on the inhibition of hepatitis B viral expression in vitro via specific receptors mediated ribozyme transfer]Y Li
Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences, Beijing 100050
Zhonghua Shi Yan He Lin Chuang Bing Du Xue Za Zhi 11:110-3. 1997....
- Characterization of the asialoglycoprotein receptor under hypoxic conditions in primary cultured rat hepatocytesA Hon Kwon
Department of Surgery, Kansai Medical University, Osaka 570 8507, Japan
J Nucl Med 46:321-5. 2005..99m)Tc-Galactosyl-human serum albumin is a liver scintigraphic agent that binds to asialoglycoprotein receptors (ASGP-R) on hepatocytes. We determined the number of ASGP-R during hypoxic conditions in primary cultured rat hepatocytes...
- The lobular expression of the rat asialoglycoprotein receptor is regulated at the posttranscriptional levelMara Massimi
Department of Basic and Applied Biology, University of L Aquila, 67010 L Aquila, Italy
Liver Int 25:184-93. 2005..These findings indicate that the distribution of ASGP-R is heterogeneous across the liver lobule, with a pattern of expression prevalently modulated at the posttranscriptional level...
- Autoantibodies against CYP2D6 and other drug-metabolizing enzymes in autoimmune hepatitis type 2Takaharu Mizutani
Graduate School of Pharmaceutical Sciences, Nagoya City University, Nagoya, Japan
Drug Metab Rev 37:235-52. 2005..Autoantibodies against CYP11A1, CYP17, and/or CYP21 involved in the synthesis of steroid hormones are also detected in patients with adrenal failure, gonadal failure, and/or Addison disease...
- The B domain of coagulation factor VIII interacts with the asialoglycoprotein receptorN Bovenschen
Department of Plasma Proteins, Sanquin Research at CLB, Amsterdam, The Netherlands
J Thromb Haemost 3:1257-65. 2005..Because FVIII clearance in the presence of a bolus injection of RAP still occurs fairly efficient, also RAP-independent mechanisms are likely to be involved...
- The asialoglycoprotein receptor clears glycoconjugates terminating with sialic acid alpha 2,6GalNAcEric I Park
Department of Pathology, Washington University School of Medicine, St Louis, MO 63110, USA
Proc Natl Acad Sci U S A 102:17125-9. 2005....
- Interaction between desialylated hepatitis B virus and asialoglycoprotein receptor on hepatocytes may be indispensable for viral binding and entryT Owada
Hokkaido Red Cross Blood Center, Nishi ku, Sapporo shi, Hokkaido, Japan
J Viral Hepat 13:11-8. 2006..We concluded that this method makes it feasible to evaluate the infectivity of HBV in vitro and that ASGP-R may be a specific HBV receptor once viral particles are desialylated...
- Copolymers for hepatocyte-specific targeting carrying galactose and hydrophobic alkyl groupsTakahiro Hiratsuka
Department of Biomolecular Engineering, Tokyo Institute of Technology, Yokohama 226 8501, Japan
Macromol Biosci 8:231-8. 2008..The copolymers efficiently delivered a water-insoluble drug to the hepatocytes. Hence, they be used to deliver hydrophobic drugs to cure various liver diseases...
Research Grants11
- OLIGOSACCHARIDE STRUCTURE &FUNCTION IN RECOGNITIONJacques U Baenziger; Fiscal Year: 2012..We will define how these receptors control the concentrations of hormones and inflammatory proteins during pregnancy and the response to injury. ..
- KARIN MARIA HOFFMEISTER; Fiscal Year: 2016..We will survey platelet glycoproteins from mice deficient for the hepatic asialoglycoprotein receptor2 (Asgr2), the macrophage galactose lectin (MGL), or both to define the glycan- bearing platelet ligands for the Asgr and ..
- MOLECULAR ABERRANCIES OF IGA IN IGA NEPHROPATHYMilan Tomana; Fiscal Year: 2001..Results of these studies should provide information concerning the behavior of structurally altered IgA1 proteins and provide a rational explanation for their deposition in kidney mesangium of IgAN patients. ..
- REGULATION OF RECEPTOR MEDIATED ENDOCYTOSIS--HUMAN CELLRobert Fallon; Fiscal Year: 1990..This will permit, when combined with the requisite biochemical tools, detailed studies on a molecular level into the pathophysiology of bone marrow failure syndromes, both congenital and acquired...
- Dietary Modulation of Sialic Acid ModificationsEric I Park; Fiscal Year: 2010..This proposal is designed to test a novel mechanism for how a majority of circulating proteins may be removed from the circulation. ..
- Structure-Function Analysis of LactoferrinDOUGLAS MCABEE; Fiscal Year: 2002..Lt sub-domains, which when removed from Lf-Tf hybrids elicit a loss-of-binding phenotype, will be placed into a Tf background to determine if they confer a gain-of-binding phenotype on Tf. ..
- OLIGOMERIZATION AND FOLDING OF MEMBRANE PROTEINSRebecca Wells; Fiscal Year: 1999..Understanding the process of oligomer formation will provide insights into the structure of these two important receptors and will ultimately lead to an understanding of the relationship between their structure and function. ..
- OLIGOSACCHARIDE STRUCTURE AND FUNCTION IN RECOGNITIONJACQUES BAENZIGER; Fiscal Year: 2007..An understanding of these fundamental processes will ultimately yield insights that can aid in evaluating changes in plasma proteins for diagnostic and theraputic purposes. ..
- GLYCOPEPTIDES AS TARGETED DRUG DELIVERY CARRIERSKEVIN RICE; Fiscal Year: 2000..These are important factors towards developing a safe and effective receptor mediated gene delivery system for in vivo use in humans. ..
- Effects of Ethanol on Endocytosis in the LiverCAROL CASEY; Fiscal Year: 2009..This increased fibronectin concentration contributes to the pathogenesis of liver injury by its role in the initiation of the fibrogenic cascade ..
- Anti-oxidative gene therapy for liver transplantationJian Wu; Fiscal Year: 2006..unreadable] [unreadable] [unreadable]..


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|Message view
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|Claus Ibsen <claus.ib...@gmail.com>
|Re: Invoking .tokenizeXML from a custom processor
|Tue, 02 Apr 2013 06:47:09 GMT
Hi You can use the Tokenize language org.apache.camel.language.tokenizer.TokenizeLanguage It has a number of static methods to easily create the expression. Then you can use that from a processor. On Tue, Apr 2, 2013 at 7:29 AM, dkum003 <firstname.lastname@example.com> wrote: > > Hi, > > I am aware that we can invoke the .tokenizeXML from the route builder. But > is there a way to invoke this through a processor. > > Say i want to split the xml to write it to a set of xml tags. I do not want > to write custom logic using xpath/dom to split this. Instead i would like > to > use camel's .tokenizeXML method. > > Could you please guide me on this. > > Regards, > Dhananjay > > > > -- > View this message in context: > http://camel.465427.n5.nabble.com/Invoking-tokenizeXML-from-a-custom-processor-tp5730189.html > Sent from the Camel - Users mailing list archive at Nabble.com. > -- Claus Ibsen ----------------- Red Hat, Inc. FuseSource is now part of Red Hat Email: firstname.lastname@example.com Web: http://fusesource.com Twitter: davsclaus Blog: http://davsclaus.com Author of Camel in Action: http://www.manning.com/ibsen
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Question about Zonet Computers & Internet
Attempting to set up for Client Mode; manual instructions are incomplete. I select radio button 5 (Client) Wizard asks for preferable mode twice so I select (Client) in the second box I enter name of my wireless router JnKBull Channel set to 11 (box to right shows Frequency 2.462 GHz WDS mode: selected Static Key Remote AP Mac I entered Mac address of my wireless router. The wizard requests SSID a second time, I entered JnKBull Request channel number , I selected 11 and input the MAC address of JnKBull I enabled Encryption Select WPA_PSK Select ASCII Key type Select AES Cipher Key: entered the encryption Key for JnKBull wireless router. Select Apply and get message "Configure Mode Failure" The manual only shows setup for the lower part of the Wizard screen. What am I missing?
Posted by Anonymous on
SOURCE: I have freestanding Series 8 dishwasher. Lately during the filling cycle water hammer is occurring. How can this be resolved
a 6ya expert can help you resolve that issue over the phone in a minute or two.
Best thing about this new service is that you are never placed on hold and get to talk to real repairmen in the US.
New users get 2 Free calls (no credit card required) and instant help on almost anything you can think of (from cars to computers, appliances, handyman, and even pets).
click here to download the app (for users in the US for now) and get all the help you need.
Posted on Jan 02, 2017
SOURCE: I have a Netgear wireless router DG834G and i am
Please follow the steps on a computer connected to the router so as to check the network key:
1. Open the browser(Internet Explorer or Mozilla Firefox).
2. Access the router usually http://192.168.0.1 else try http://www.routerlogin.com
3. Login to the router with the Username as admin and password as password (unless you have changed it).
4. Click on Wireless Settings'(under Setup) from the left menu.
5. Check if 'WEP (Wired Equivalent Privacy)' or 'WPA-PSK (Wi-Fi Protected Access Pre-Shared Key)' is selected under 'Security Options'.
6. If WPA-PSK is selected, copy the code entered in the passphrase.
7. If WEP is selected, copy the code entered in the key that has been checked.
This is the code required for connecting the wireless computer to the routers' wireless network.
In some cases, for security reasons the passphrase might show as asterisks. In this case type a new password and click apply. You will then have to use the same password for all the wireless devices connecting to the network.
I hope this information allows you to resolve this issue.
If I have helped you, please help me, and rate this suggestion the highest FixYa rating. If you cannot rate this post with the highest rating, then please comment to this post and I will try to help you further.
Posted on Sep 13, 2009
SOURCE: My wireless name (SSID) and security settings keep changing on their own!
well i saw the problem u r facing
and the only soution for it is the upgradation of the firmware ....
i was facing the same one on my router and it got corrected ....
otherwise u can call the customer care no of the the routers company and they will give u the replacement
Posted on Oct 23, 2008
SOURCE: USB Wireless Network Setup Values
during setup it should asked you to create password but anyways those letters are security protocals for your router to prevent peeps from accessing your network...wep is easiest
Posted on Dec 02, 2008
SOURCE: I installed a new Zoom
I think the router firmware is not working properly.
Some routers need power cycle ( reboot ) after any changes on the router settings.
Now make sure that you are getting IP address on the internet part of the router.
When you set up WEP and passphrase , Your actual password for the wireless network will be the number in the key number 1 box and NOT the passphrase.
Click Here for more info about networking.
Posted on Oct 08, 2009
SOURCE: Followed instructions from Best Solution posted on
If you select WPA security mode then you can not add the network manually.
I think the OS on your computer is windows XP.
You can connect to the netwoek using the windws utility.
If you select WEP, then you can add the network manually.
Click here for more information about router and networking
Posted on Feb 16, 2010
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This virtual collection invites students into an engaging exploration of the Civil Rights Movement.
Lupita Nyong'o, Carmelo Anthony and Ana Navarro investigate the political choices of their fathers, discovering sometimes unexpected heritage as they trace their ancestry further back. Monday, November 20 at 7 pm
On Second Thought is a one-hour, daily news talk show that airs at 9 a.m. ET weekdays.
The State Workforce Development Board plays an integral role in ensuring Georgia remains tops in workforce development.
So, now we're at 144…
Make your secure online donation at GPB.org.
A scientist at the Georgia Bureau of Investigation explains the formal definition of "latent print." (that's "finger print" to you and me)
This content was developed under a grant from the U.S. Department of Education. However, this content does not necessarily represent the policy of the U.S. Department of Education, and you should not assume endorsement by the Federal Government.


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Graduate student Sarah E. Hopson is a Fall 2015 recipient of the Outstanding Graduate Student Teaching Award as announced by the Graduate School.
Hopson's advisor is Marty Thompson.
Graduate student Sarah E. Hopson is a Fall 2015 recipient of the Outstanding Graduate Student Teaching Award as announced by the Graduate School.
Hopson's advisor is Marty Thompson.
Graduate student Melanie Talaga is a Spring 2016 recipient of the Dean's Award for Outstanding Scholarship, as announced by the Graduate School.
Talaga's advisor is Tarun Dam.
Talaga also received the Third Place Award for an Oral Presentation at the 2016 Graduate Research Colloquium. Hers was the Highest Attended Presentation.
Graduate students displaying research at Michigan Tech
"We use really big words and we're use to using those words because we deal with it everyday," said Melanie Talaga, MTU doctorate student. "Other general communities do not understand those words so we need to learn how to practice and break it down to everyone's level. So then we can communicate our science and get people interested in our science."
Read more at Upper Michigan's Source, by Aleah Hordges.
The William G. Jackson Center for Teaching and Learning seeks input for its annual Distinguished Teaching Awards, which recognize outstanding contribution to the instructional mission of the University.
Based on more than 50,000 student rating of instruction responses, 11 finalists have been identified for the 2016 awards. The selection committee is soliciting comments from students, staff, faculty and alumni to aid in its deliberation process.
Among the finalists in the Assistant Professor / Lecturer / Professor of Practice Category is Lecturer Andrew Galerneau.
Comments on the nominees are due by Friday, March 18, 2016, and can be completed online.
From Tech Today, by by Jackson Center For Teaching and Learning.
Kathryn Perrine joins the Department of Chemistry as an assistant professor. Before joining Michigan Tech, Perrine was at the Joint Center for Artificial Photosynthesis at the California Institute of Technology. Perrine earned her PhD in Chemistry from the University of Delaware and her Bachelor of Science in Chemistry from the University of South Carolina.
She belongs to the American Vacuum Society and the American Chemical Society. Her research interests include reactions on metal and functionalized surfaces to control the growth of molecular architectures; growth, properties and reactions on heterogeneous structures for energy analysis; and liquid/solid and gas/solid interfacial chemistry using surface analysis.
Graduate students Jingtuo Zhang, Mu Yang, Wafa Mazi, Mingxi Fang, Fei Xie, Postdoctoral Associate Kapil Adhikari, Assistant Professor Loredana Valenzano, Associate Professor Ashutosh Tiwari and full Professor Haiying Liu (all from the chemistry department) published a paper entitled, "Unusual Fluorescent Responses of Morpholine-Functionalized Fluorescent Probes to pH via Manipulation of BODIPY's HOMO and LUMO Energy Orbitals for Intracellular pH Detection," in ACS Sensors. This project is funded by NIH.
DOI: 10.1021/acssensors.5b00065
Lynn Mazzoleni (Chem), was recently awarded a Fulbright Scholar Award to study one of Europe's pollution hot spots. Currently on sabbatical in Bologna, Italy, Mazzoleni is collaborating with researchers in the Institute of Atmospheric Sciences and Climate at the Italian National Research Council. Their study focuses on the chemistry of atmospheric nitrogen species to improve the understanding of aqueous phase chemistry that contributes to the high concentrations of aerosol pollution.
Dr. Donald Bergstrom
Professor Emeritus
Department of Medical Chemistry and Molecular Pharmacology,
Purdue University, West Lafayette, Indiana
Date: October 16, 2015
Place: Chem-Sci Room 101
Time: 3:00 pm
For more than a half century I have designed and created new molecules. My research has been shaped within the contexts of culture, time, and place, at times responding to the work of others, but always attempting to ride the wave front of science. "At the End of Chemistry" follows the trajectory of my research from rocket design in the 1950's to nanomaterials in the 21st century. It is both report and inquiry about the nature of research.
Don Bergstrom has held faculty positions at Purdue University (1989-2011), the University of North Dakota, and the University of California, Davis. He holds degrees in chemistry from the University of Washington (BS, 1965) and the University of California, Berkeley (PhD, 1970). From the early 1970s the work in his laboratory focused on nucleic acid chemistry, particularly the synthetic chemistry and applications of nucleosides. In the 21st century his efforts expanded into areas of nanotechnology and new approaches to drug design based on concepts of molecular self-assembly. He is currently a 2nd year graduate student in the MFA program in Applied Craft + Design at the Pacific Northwest College of Art.
LSTI 1st Annual Research Forum a Success
The First Annual Research Forum sponsored by the Life Science and Technology Institute was held Sept. 24 and 25. Twenty-seven graduate and undergraduate students conducting research in life science, biotechnology, human health and related areas presented posters.
Among the Graduate Merit Award winners was:
Ni Fan (Chem)—"Glycan-Dependent Mutual and Reversible Sequestration," Advisor: Dam
Read more at Tech Today. View the photo gallery "Life Sciences at Michigan Tech."
More participants from the Department of Chemistry:
Dr. Ayyalusamy Ramamoorthy, Professor
Biophysics and Department of Chemistry, University of Michigan
Date: September 25, 2015
Place: Chem-Sci Room 101
Time: 3:00 pm
Membrane proteins are an exciting class of biomacromolecules and play important roles in a variety of biological processes that are directly linked to major diseases including cancer, aging-related diseases, and infectious diseases. A complete understanding of their function can only be accomplished using high-resolution structures and dynamics. In spite of recent developments in structural biology, membrane proteins continue to pose tremendous challenges to most biophysical techniques. A major area of research in my group is focused on the development of NMR techniques to study the dynamic structures of membrane bound proteins such as cytochrome b5, cytochrome P450 and cytochrome P450-reductase. In my talk, I will present strategies to study the structure and dynamics of these challenging systems and also on the electron transfer mechanism that enables the enzymatic function of P450. Atomic-level resolution NMR structures of amyloidogenic proteins revealing the misfolding pathway and early intermediates that play key roles in amyloid toxicity will also be presented.
J. Biol. Chem. (2015) 290:12705-18; 290: 4843-55; 288:22080-95.
Chem. Soc. Rev. (2014) 43:6692-6700; J. Phys. Chem. Lett. (2014) 5:1864.
Dr. Ayyalusamy Ramamoorthy is Professor of Biophysics and Chemistry at University of Michigan, where he has been since 1996. He has applied NMR spectroscopy and other biophysical techniques to investigate high-resolution structure, dynamics, and functional properties of membrane proteins, amyloid proteins/peptides, and antimicrobial peptides. He has published more than 250 peer-reviewed papers in leading high impact journals like Science, PNAS, JACS, J. Biol. Chem., and Angew. Chem. Eng. Intl., written several review articles, edited 2 books on NMR spectroscopy, brought out several special issues as a guest editor, and organized several conferences related to NMR spectroscopy. He is a member of editorial boards of J. Biol. Chem., Plos One, Scientific Reports, Peer J, Biochimica Biophysica Acta, Journal of Magnetic Resonance, Chemistry and Physics of Lipids, Solid State Nuclear Magnetic Resonance Spectroscopy, and Magnetic Resonance in Chemistry. He has been a PI or co-PI on several NIH (and other) sponsored projects.
For more information visit http://rams.biop.lsa.umich.edu/
Dr. Xiaohu Xia
Assistant Professor
Department of Chemistry, Michigan Tech
September 18, 2015
Chem-Sci Room 101 3:00pm
Peroxidase mimics (or artificial peroxidase) with dimensions at the nanoscale have received great interest as emerging artificial enzymes for biomedicine and environmental protection. While a variety of peroxidase mimics have been actively developed since 2007, limited progress has been made toward improving their catalytic efficiency. In our recent work (ACS Nano, 2015, in press, DOI: 10.1021/acsnano.5b03525), we reported a novel type of peroxidase mimic with record high efficiency. Our peroxidase mimic was engineered by depositing Ir atoms as ultrathin skins (a few atomic layers) on Pd nanocubes (i.e., Pd-Ir cubes). The Pd-Ir cubes exhibited significantly enhanced efficiency that is over 400-fold higher than that of natural peroxidase. In this talk, I will introduce the rational design, experimental synthesis, and mechanistic understanding of such a new peroxidase mimic. At the end, using human prostate specific antigen as a model example, I will highlight the application of our peroxidase mimic in ultrasensitive detection of disease biomarkers.


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Minet El Hosn Po Box 846/11, Beirut, Lebanon (Show map)
The apartment features an elevator and a restaurant. This property offers housekeeping, shuttle service and ironing service.
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When you create an account with us, you'll be able to save your favourite books, make a wishlist of upcoming titles, receive newsletters about books you'll love, get recommendations tailored to you and order our books directly. Join us by creating an account and start getting the best experience from our website!
A searing modern polemic from the BAFTA- and MOBO-award-winning musician and political commentator, AkalaFrom the first time he was stopped and searched as a child, to the day he realised his mum was white, to his first encounters with racist teachers - race and class have shaped Akala's life and outlook. In this unique book he takes his own experiences and widens them out to look at the social, historical and political factors that have left us where we are today.Covering everything from the police, education and identity to politics, sexual objectification and the far right, Natives will speak directly to British denial and squeamishness when it comes to confronting issues of race and class that are at the heart of the legacy of Britain's racialised empire.
Sunday Times Number One Bestseller Happy Mum Happy Baby is now a Number One podcast. A positive and uplifting book about what it is to be a mother and all things mum and baby by Celebrity Mum of the Year and phenomenally popular vlogger, author, TV presenter and actress Giovanna Fletcher.Being a mum is an incredible journey, a remarkable experience that changes how we look, how we feel, who we are. As mothers we are strong, protective, proud. We feel a love like no other.But being a parent can be hard too. It challenges us physically, mentally, emotionally. There are the days where just managing to fit a shower in amidst the endless feeding, entertaining young children and surviving on a lack of sleep feels like an achievement. With so many people ready to offer 'advice' on the best way to parent, it can feel like you are getting it all wrong.Since Giovanna and her husband Tom Fletcher have had their sons Buzz and Buddy, they have been sharing glimpses of their family life. With an infectiously positive outlook and happy take on all things mum-related, Giovanna has developed a following of fellow parents and mums-to-be.This is not a book about how to have the perfect family experience - Gi would be the first to admit she is winging it just as much as the rest of us - instead it is an honest, upbeat and incredibly personal account of her own experience of having a family. In Happy Mum, Happy Baby Giovanna shares her own journey through parenthood and in doing so, she looks at what it is to be a mother today, encourages you to be confident in yourself as a parent and celebrates how putting a focus on being a happy and confident mum can really make for a happy baby.
Social Media Marketing In A Week is a simple and straightforward guide to mastering the basics, giving you everything you need to know in just seven short chapters. From making the right first impression and having a unified message and strategy, to knowing where your audience is, engaging them and managing your reputation, you'll discover how to build a relationship with your customers on sites like Facebook, YouTube, Flickr and Pinterest, without selling to them. This book shows you how to get started with social media giving you the ability and best practice to interact confidently with your fans and subscribers. Whether you choose to read it in a week or in a single sitting, Social Media In A Week is your fastest route to success:- Monday: Gain insight with cases studies of companies that have achieved positive results from social media- Tuesday: Get started with key strategies and tactics and learn how to find and engage with your audience- Wednesday: Learn how to set up and configure Blogging, Facebook, Twitter and LinkedIn- Thursday: Learn how to set up and configure YouTube, Google, Pinterest, StumbleUpon, and other ones to watch- Friday: Utilize other people's content to help you become the authority in your marketplace, in one hour a day or less- Saturday: Discover the tools and techniques that will help you to continually manage your social media campaignABOUT THE SERIESIn A Week books are for managers, leaders, and business executives who want to succeed at work. From negotiating and content marketing to finance and social media, the In A Week series covers the business topics that really matter and that will help you make a difference today. Written in straightforward English, each book is structured as a seven-day course so that with just a little work each day, you will quickly master the subject. In a fast-changing world, this series enables readers not just to get up to speed, but to get ahead.
THE NEW YORK TIMES BESTSELLER'A LOT OF US WOULD LIKE A RUBIN IN OUR LIVES' The Times Magazine - 'JUST READ THIS BOOK... IT'S EXCELLENT' Viv Groskop - 'FASCINATING, PERSUASIVE' GuardianGretchen Rubin, author of the blockbuster New York Times bestsellers, The Happiness Project and Happier at Home, has helped millions of readers get happier. Now she tackles the critical question: How can we make good habits and break bad ones? Many experts suggest one-size-fits-all solutions for habit change, but as we all know from experience, there's no single magic answer. Better Than Before shows us how to understand habits and to change them for good, and gives us the thrill of recognition and relief, because at last, we'll have the vocabulary and framework to change our habits successfully. Solutions exist!Along the way, Rubin uses herself as a guinea pig, tests her theories on family and friends, and answers some of the most pressing questions - oddly, questions that other writers and researchers tend to ignore: - Why do I find it tough to create a habit for something I love to do?- I want to help someone else make a change. But how?- Why do practically all dieters gain the weight back - plus more?- How quickly can I change a habit?- Why can I make time for everyone else, but can't make time for myself?Whether you want to get more sleep, finish a project, maintain a healthy weight, or stop checking devices, habits make it possible. With Rubin's signature mix of rigorous research and easy humour, Better Than Before will make us eager to start work on our own habits - even before we've finished the book.(P)2015 John Murray Press
The bestselling debut cookbook from Deliciously Ella that's taken the healthy eating world by storm!From sumptuous desserts, to food on the go, delicious dips, raw treats and rainbow bowls of awesome veggies, Ella's philosophy is all about embracing the natural foods that your body loves and creating fresh, simple dishes which are easy to make and taste amazing. Featuring more than 100 new sugar-free, gluten-free and dairy-free recipes to excite your taste buds, this collection will inspire you to eat for better health, glowing skin and boundless energy.A reformed sugar monster herself, Ella knows just how daunting the idea of changing your diet can be. Her must-read blog, DELICIOUSLY ELLA, which gets two million visitors a month from all over the world, was inspired by her own health adventure and everything she has learned by healing herself simply through diet. It's truly amazing to see what you can do with these simple ingredients and how you can so easily create a deliciously healthy version of your favourite dishes.More than anything, Ella wants to show that this way of eating is absolutely not about deprivation and starvation, but instead is about embracing a positive, healthy way of life.
The NUMBER ONE bestseller from the author of Small Great Things, 'To Kill a Mockingbird for the 21st Century' (Reader Review) For seventy years, Josef Weber has been hiding in plain sight.He is a pillar of his local community.He is also a murderer.When Josef decides to confess, it is to Sage Singer, a young woman who trusts him as her friend. What she hears shatters everything she thought she knew and believed.As Sage uncovers the truth from the darkest horrors of war, she must follow a twisting trail between terror and mercy, betrayal and forgiveness, love - and revenge.'She is a master of her craft . . . and humanity is what Picoult does best' Sunday Telegraph
Hodder & Stoughton imprint Coronet is delighted to announce that it will publish an illustrated memoir by number one bestselling British music artist, Conor Maynard. Click READ for more.
Giovanna grew up in Essex with her Italian dad Mario, mum Kim, big sister Giorgina and little brother Mario, and with family playing such a big part of her life it was only natural that she had always dreamed of having children of her own. Giovanna and her husband Tom Fletcher have two young sons Buzz and Buddy and share glimpses of their family life through their YouTube channels (giovannasworld) and on their social media (twitter: @mrsgifletcher, facebook: MrsGiFletcher and Instagram: mrsgifletcher). A bestselling novelist, actress, TV presenter, vlogger and blogger, Giovanna is most importantly a mum and her pledge to spread positivity wherever she goes has earned her a vast following.


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Planning a first visit to the Walt Disney World Resort? Planning a Disney vacation for the first time can be overwhelming, but there are some things you just shouldn't miss: 1. How early you need to make reservations This goes for resort accommodations, dining reservations, FastPass selections, basically anything that could potentially be reserved in advance. Many first-timers assume ...Read More »
Author Archives: Brittany DiCologero
12 Tips For A Great Day At Walt Disney World's Animal Kingdom
Disney's Animal Kingdom has expanded and changed so much over the years, that you may not be used to thinking of it as a "full day park." With the recent Pandora expansion, there is so much to see and do! Check out these 12 tips for a great day at Walt Disney World's Animal Kingdom. 1. Arrive early To get ...Read More »
11 Rookie Mistakes While Dining At Walt Disney World And How To Avoid Them
With so much planning going into a Walt Disney World vacation, it is not surprising that many guests experience a couple of hiccups with their dining plans. Check out our tips for avoiding these pitfalls below, and start planning your Disney dining adventures today. 1. Failing to make reservations in advance The worst mistake you can make when it comes ...Read More »
12 Walt Disney World Special Items For Your Bucket List
Whether you're a seasoned Walt Disney World guest or you're new to the game, putting together a bucket list is a fun way to remember all of your experiences from your trips. Read on to learn about our bucket list items, and let us know what you've done or what you'd add in the comments! 1. Stay in a ...Read More »
8 Totally Cool Things You'll Love About Boma At Animal Kingdom Lodge
1. Location Animal Kingdom Lodge is one of the most beautiful resorts at Walt Disney World. With the Lodge being right on its own savannah, you can head outside and see some of the animals that live there before or after your meal. The resort is also home to an awe-inspiring lobby, relaxing bars and lounges, and a guest-favorite resort ...Read More »
10 Suggestions For Having A Great Day At Walt Disney World's Animal Kingdom
1. Plan Ahead If you've visited Disney's Animal Kingdom in recent years, you may not have thought much about planning ahead. Unlike some of the other parks, you were generally able to get FastPasses and even dining reservations the day of your visit. With the park's extended hours and the opening of Pandora: World of Avatar, this perception has finally ...Read More »
Disney After Dark: 10 Things You Must Do Around the Walt Disney World Resort at Night
1. See the fireworks Seeing the fireworks while visiting the Walt Disney World Resort is a given, but since there are so many different nightly spectaculars now you may need to put in some extra planning to ensure that you can see them all. (The extra planning is especially useful for Hollywood Studios, where it is not always possible to ...Read More »
10 Rookie Mistakes At Epcot in Walt Disney World And How To Avoid Them
1. Breezing through Future World You probably won't skip the most popular attractions in Future World like Test Track, Soarin, Mission Space and Spaceship Earth, but there are a couple of other underrated attractions that sometimes go unnoticed. You can easily spend an hour or two at the Seas with Nemo and Friends, and other attractions like Journey Into Imagination, ...Read More »
10 Ways to Survive a Crowded Day at Walt Disney World's Magic Kingdom
1. Stay at a Disney resort Staying at a Disney resort can help you when it comes to dealing with crowds for a couple of reasons. For one, getting to the Magic Kingdom will be easier, as you'll be able to bypass the parking lot to the monorail or ferry at the Transportation and Ticket Center by taking a bus, ...Read More »
10 Rookie Mistakes at Walt Disney World's Magic Kingdom and How to Avoid Them
1. Sleeping in too late The morning is undoubtedly the best time to be in the Magic Kingdom, and while sleeping in can obviously be relaxing, you would be doing so at the sacrifice of a beautiful morning in the park. Certain entertainment offerings only take place in the morning, and lines for attractions tend to be short when the ...Read More »


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This week, we detected unusual access patterns that led to us identifying unauthorized access attempts to Twitter user data. We discovered one live attack and were able to shut it down in process moments later. However, our investigation has thus far indicated that the attackers may have had access to limited user information – usernames, email addresses, session tokens and encrypted/salted versions of passwords – for approximately 250,000 users.
Tag Archives: password breach
Adobe's connectusers.com breached – 150,000 credentials stolen
Just another friendly reminder to avoid reusing passwords across sites!
via Adobe Hacker Says He Used SQL Injection To Grab Database Of 150,000 User Accounts – Dark Reading.


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My Mother's Silver Cupboard Full of Memories
Her memories were locked away in that cupboard. It belonged to her and only her and held only her things. Nobody was allowed to touch it or open it–ever. The keys were tucked in her waist on her sari, at any given time of day or night.


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A Father's Day morning feast
Published 4:00 am, Sunday, June 20, 2010
Today is my first Father's Day as a dad. I've never felt much affinity for commercially inspired holidays (which eliminates almost all of them), but if I can use the occasion to wrangle one of the greatest breakfasts of all time, then I'm all for it.
I grew up eating trout. My father carried a set of fishing poles (it seems he required three) in the family car, and would stop off for a quick hit of his addiction at the lake on the way home from work.
He almost always came home with at least a few trout. We often had them for dinner, but, just as often, he cooked them up in the morning just for the two of us; everyone else in the family winced at the prospect of eating fish for breakfast, but that just meant more for us.
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It's been a while since I've had just-caught trout. Today all the trout I can find comes from a farm in Idaho, but I still love it. When it's cooked properly - with a spiced cornmeal crust, that is, and fried in a cast-iron pan - and served with chile-laden potato hash and a couple of over-easy eggs, you know it's going to be a good day.
I've experimented with lots of cooking methods for trout over the years, but I've finally settled on one that produces perfectly crispy and delicious skin and moist, wonderfully seasoned flesh.
Rinse the fish and dry it carefully and thoroughly. Then take your sharp knife and scrape along both sides of the fish. You'll get some funky grayish stuff on the knife - wipe it off with a paper towel, and do it some more, until you no longer produce any gray muck.
This wonderful technique applies to almost all fish; it removes all impurities, and paves the way for wonderfully crispy, scrumptious skin when it hits a hot oiled pan.
With a plate of potato hash, a few eggs and a cup of chai to go with my trout, I'm ready to roll. Seven-month-old Daphne can't enjoy this one with me quite yet, but with some luck, she'll develop a taste for fish in the morning with her papa, too.
Pan-Fried Trout With Polenta-Spice Crust
Serves 2 to 4
Serve with eggs over-easy and an amped-up plate of potato hash (see recipe below).
- 1 tablespoon polenta or cornmeal
- 1 teaspoon fennel seeds
- 1 teaspoon coriander seeds
- 1 teaspoon black peppercorns
- 1 teaspoon kosher salt
- 2 whole, medium-large trout (about 8 ounces each), head and tail removed
- -- Olive oil
- 1 tablespoon unsalted butter
- -- Wedges of lemon or other citrus
Instructions: Preheat oven to 400°. Place polenta or cornmeal, fennel and coriander seeds, peppercorns and salt in a spice grinder or an electric coffee grinder used only for spices. Grind to a fine powder. Set aside.
Remove fish from refrigerator 30 minutes before cooking. Use the sharp edge of a knife and slight pressure to scrape both sides of the fish. Discard any resulting grayish sludge; continue to scrape until the skin is ultra clean. Rub the entire fish - inside and out - with small drizzles of olive oil.
Melt 1 tablespoon olive oil and the butter in a large cast-iron or other heavy, oven-safe pan over medium-high heat.
While the pan heats, evenly sprinkle the polenta spice mixture onto both sides of the trout, then firmly press on to help it stick. Gently place the fish into the hot pan, and cook, undisturbed, for 3 to 5 minutes, or until deeply browned. Use tongs or a spatula to gently flip the fish over and cook for a minute or two more. Stuff the lemon wedges inside the fish, then transfer the pan to the oven. Roast for about 5 minutes, or until flesh is firm and opaque.
Remove the trout from the pan and place on warm plates. Squeeze the baked lemon wedges over the fish and sprinkle lightly with salt. Serve immediately.
Per serving: 153 calories, 18 g protein, 2 g carbohydrate, 8 g fat (3 g saturated), 58 mg cholesterol, 564 mg sodium, 1 g fiber.
Fiery Potato Hash
Serves 4
This is a quick, homey and pretty spicy version of fried potatoes. Increase or decrease heat per your taste.
- 1 tablespoon unsalted butter
- 1 tablespoon olive oil
- 4 cups diced skin-on potato, about 1 pound (small red creamers work well)
- -- Sea salt to taste
- 1 cup diced onion
- 1 teaspoon chipotle powder
- 1 fresh jalapeno, seeds removed, minced
- -- Handful of chopped cilantro (optional)
Instructions: Melt the butter and olive oil in a heavy (ideally, nonstick) skillet over medium heat. Add the potato, salt liberally, and cook for about 5 minutes, stirring often. Add the onion, chipotle powder and jalapeno. Increase heat to medium-high and continue to cook, stirring occasionally, another 15 to 20 minutes, or until potatoes are crisp on the outside and soft on the inside. Taste for salt, garnish with the optional cilantro and serve hot.
Per serving: 193 calories, 4 g protein, 31 g carbohydrate, 7 g fat (2 g saturated), 8 mg cholesterol, 11 mg sodium, 3 g fiber.


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Mainstays Outdoor Cushions
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Dine at a local breakfast spot in St. Augustine before experiencing all the exciting things to do in the nation's oldest city! There are many delicious restaurants and cafes dedicated to breakfast and lunch, as well as many delectable bakeries and eateries perfect for grabbing a quick bite.
Beautifully-served fusion cuisine and comfort food for breakfast and lunch in the heart of downtown St. Augustine.
Sheila's Café at Anastasia Kitchen in historic St. Augustine, Florida serves up delicious and affordable menu items! This restaurant is located on Anastasia Island at beautiful Saint Augustine Beach.
A Southern staple fast food chain specializing in Chicken Sandwiches!
Burger Buckets offers moderately-priced breakfast and lunch specialties, as well as delicious ice cream and homemade fudge.
This popular St. Augustine sandwich shop is back, serving its signature Ryder sandwiches and a new breakfast menu.
Georgie's Diner specializes in authentic Greek cuisine and is a local favorite for breakfast, lunch, and dinner. Located in the historic district of Saint Augustine, this is a great place for the whole family to enjoy a meal.
Vince's Sandwich Shop in historic St. Augustine is located inside the Ameris Bank Building at Southpark Blvd. They offer great sandwiches, wraps, and salads, all made from fresh ingredients.
Enjoy home-cooked food at this family-owned restaurant in St. Augustine.
The Everything Bagel Company is located in the Riverside/Hobby Lobby Plaza on State Road 312 in St. Augustine, Florida.
Dunkin' Donuts is the world's largest coffee and baked goods chain, serving more than 3 million customers per day.
"Where the Locals Eat!"
Manatee Café in St. Augustine, Florida specializes in fresh and healthy food options. At Manatee Café breakfast is served all day!
Historic downtown coffee shop serving up organic coffee and tea as well as delicious pastries, fresh sandwiches, crepes and more
Enjoy tasty and delicious fresh baked goods at the Bunnery Cafe located in historic downtown St. Augustine.
Denny's restaurants offer a casual dining atmosphere and moderately priced meals served 24 hours a day. Denny's is best known for its breakfasts served around the clock, including the popular Meat Lover's Breakfast and Original Grand Slam.
This restaurant in historic downtown puts out excellent food for breakfast, lunch, and dinner every night of the week!
Zaba's is a locally owned and operated coffee shop in St. Augustine Beach. They are located just a block from the ocean with a cafe shop selling iced and hot coffees. Visitors can drink Espressos, Lattes, Frappes or delicious Smoothies.
Serving fresh-baked goods for breakfast and lunch, this cafe offers something for everyone and is the home of Datil B Good hot sauces.
Village Inn serves up breakfast, lunch, and dinner in a family friendly diner setting, but you'd better save room for pie.
Enjoy refreshing Australian coffee and pastries at this popular coffee shop in historic downtown.


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Score from 58 reviews
from 64,1 USD – Guest accommodation
from 53,4 USD – Guest accommodation
from 59,3 USD – Guest accommodation
from 58,2 USD – Guest accommodation
Guest accommodation
from 64,1 USD – Guest accommodation
from 65,3 USD – Guest accommodation
from 53,4 USD – Guest accommodation
0.04 km
Tsagarada 37012, Tsagarada
0.32 km
Tsagkarada 37012, Tsagarada
0.73 km
Tsagarada 37012, Tsagarada
0.79 km
Tsagarada 37012, Tsagarada
* Distances are measured as a straight line, calculated from a starting point to a destination point
All bookings are confirmed instantly. No waiting, no email exchanges, no confusion.
Adilon is situated in Tsagarada, 21 km from Volos. Free private parking is available on site.
Adilon features free WiFi .
You will find a 24-hour front desk at the property.
Portariá is 16 km from Adilon.
Rooms: 4
Please note that in some rooms the kitchen amenities are ideal only for breakfast preparation.
Refrigerator, Kitchenette, Coffee machine, Tea/Coffee Maker
Bathroom, Toilet paper, Shower, Toilet
Sofa, Hardwood/Parquet floors, Clothes rack, Air conditioning, Sofa bed, Wardrobe/Closet, Fold-up bed, Heating
TV, Flat-screen TV
Linen, Towels
View, Terrace, Balcony, Sea view
Upper floors accessible by stairs only
This double room has a balcony, air conditioning and sofa.
Refrigerator, Tea/Coffee Maker, Kitchenware, Coffee machine, Stovetop, Kitchen
Toilet, Toilet paper, Bathroom, Shower
Sofa, Heating, Air conditioning, Clothes rack, Wardrobe/Closet, Fireplace, Fold-up bed, Tile/Marble floor
TV, Flat-screen TV
Linen, Towels
Garden view
Entire unit located on ground floor
This studio features air conditioning, fireplace and tile/marble floor.
Kitchenette, Coffee machine, Tea/Coffee Maker, Refrigerator
Toilet paper, Toilet, Bathroom, Shower
Air conditioning, Hardwood/Parquet floors, Fireplace, Fold-up bed, Clothes rack, Wardrobe/Closet, Heating
TV, Flat-screen TV
Linen, Towels
View, Balcony, Sea view, Terrace
Upper floors accessible by stairs only
This double room features a sea-view balcony, tea/coffee maker and fireplace.
Kitchenette, Tea/Coffee Maker, Coffee machine, Refrigerator
Shower, Toilet, Bathroom, Toilet paper
Air conditioning, Seating Area, Heating, Clothes rack, Fireplace, Hardwood/Parquet floors, Sofa bed, Wardrobe/Closet, Fold-up bed, Sofa
Flat-screen TV, TV
Towels, Linen
Mountain view
Upper floors accessible by stairs only
This family room features air conditioning, sofa and kitchenette.
After booking, all of the hotel's details, including telephone and email address, are provided in the online booking confirmation, confirmation email.
Private check-in/check-out, 24-hour front desk, Express check-in/check-out
Daily maid service
Family rooms, Heating, Air conditioning
Free WiFi! WiFi is available in the hotel rooms and is free of charge.
Free parking! Free private parking is possible on site (reservation is not needed).
From 13:00 Until 18:00 hours
Until 12:00 hours
All children are welcome.
The maximum number of extra beds in a room is 1.
Pets are not allowed.
Our hotel reviews will help you find the best deal in the right location.
ihr24.com offers the choice of over 600,000 hotels in more than 200 countries.
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Style No. 34389296 ; Color Code:
Beautiful crinkly chiffon maxi gown featuring a smocked waist. Crisscross cutouts around the plunging bust. Deep V back with a hidden zipper closure. Lined.
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