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Charming Rustic Cottage, Private with Breathtaking Views!
About the property
- Cottage
- Bedrooms1
- Sleeps2
- Bathrooms1
- Half Baths0
- Minimum Stay2 nights
Cottage, 1 Bedroom + Detached Unit, 1 Bath, (Sleeps 2)
The best thing about this place is its remarkable location .... literally minutes from Stanford campus and Highway 280 ... just over the hill from the Pacific Ocean and Santa Cruz/ Half Moon Bay and yet it's the most peaceful, lovely spot imaginable with glorious views directly out to the pristine open space of the famed Windy Hill.
This is a one of a kind cottage. Great vibe with friendly, welcoming atmosphere.
Sleeps 2 with beautiful detached annex that sleeps 2 available at additional rate.
Keywords: Minutes from Stanford, Woodside, Menlo Park, Atherton with easy access to San Jose, San Francisco, Half Moon Bay and Santa Cruz. This lovely, quiet, convenient cottage with fabulous mountain views is a true gem for anyone visiting the Bay Area.
World Class Hiking!
- Response rate:
- 90%
- Response time:
- within a few hours
- Speaks:
- English
- Calendar last updated:
- May 18, 2018
What makes this Cottage unique
Fresh eggs from our beautiful hens
- Satellite or Cable
- Kids Welcome
- No Smoking
- Parking
- Pets Welcome
- Washer & Dryer
- 2 Bedrooms, Sleeps 2
- King size beds (1)
- 1 Bathroom
Location Type
- Mountain ViewWindy Hill front and center
- Guests provide their own meals
- Linens Provided
- Washing Machine
- Clothes DryerShared laundry
- Parking
- Dialup Access
- Broadband Access
- Refrigeratorsub zero
- Microwave
- Cooking Utensils
- Ice Maker
- Catering Available
- Kitchenno dw
- Dining Area
- Satellite / Cable
- Stereo
- CD Player
- DVD Player
- Music Library
- Video Library
- Outdoor Grill
- Deck / Patio
- limited accessibility
- cinemas
- museums
- restaurants
- health/beauty spa
Leisure Activities
- walking
- horseback riding
- antiquing
- sight seeing
- scenic drives
- shopping
Local Services & Businesses
- fitness center
- groceries
Sports & Adventure Activities
- tennis
- cycling
- golf
- mountain biking
- hiking
House Rules
Check-in: Flexible
Check-out: Flexible
Cancellation Policy
100% refund if canceled at least 14 days before arrival date. 50% refund if canceled at least 7 days before arrival date. You must contact the owner directly to request cancellation.
9 Reviews
Latest reviews
Clean, private, accessible to nearby trails.
Great get-away spot. We had business in Palo Alto and this spot is only fifteen minutes from Stanford but very rural and private. Views to western hills, nice outdoor patio. Definately better than the expensive hotel rooms in town.
One could not find a more delightful cottage. Serene with a fabulous view out of large windows. Spacious and well furnished. Danna is an ideal host. She is delightful and not at all intrusive.
We brought two large dogs and the neighborhood is great for nature trails for dog and human walking. My husband was out walking them one morning when a flock of 30 wild turkeys gobbled into the driveway. The dogs were a bit excited as were the turkeys when they chased them into the trees. Danna ran out to save the dogs from the turkeys!
The experience was unforgettable for us and we would recommend it to anyone.
Loved this place!
We were so lucky to get this place in time for my nephew's graduation at Stanford. We stayed for 3 days but wished we didn't have to leave. The location was incredible! The cottage beautiful. And Danna's generous hospitality amazing! We are already dreaming of coming back, next time bringing our bikes. It is gorgeous! There are walking and hiking trails close by and wonderful food options very near. We saw so much wildlife on our walks. I wish I could have bottled that beautiful fresh pine filled air. We absolutely loved it. So close to everything but you feel like you are a million miles from town. Hope to be back soon!
A lovely place to recover from surgery
My husband and I needed a place to stay close to Stanford Hospital, while he was recovering from a heart transplant. Since we were having to stay for an extended period of time I needed to find someplace where he would be comfortable. I knew it was important for me to be comfortable too, as this was going to be a stressful time and I needed to take care of myself as his caregiver.
I had looked at several options and they just weren't right. I called Danna and she suggested I come and stay a couple of nights (she was between guests) to see if it would work for us. As I left the freeway and drove up Alpine Road it was so beautiful with all of the trees, horses in pastures, very idyllic. I turned into the driveway and felt an immediate connection with the property. Large oak trees, hills in the background, and rustic looking cottage. I knew right then that was the place for us! The cottage is so comfortable. Lots of light coming in from both windows and skylights. The bed is so comfy, and the sheets are ironed and smell like out doors! Danna dries them on the line. Wonderful, wonderful!
Danna...I can't say enough about Danna. She was considerate, concerned, and became a close friend in the process. A fascinating lady! We had great discussions over wine, and she introduced me to the knitting group, and put me in touch with a friend who has horses. It was all so helpful as it helped me from feeling overwhelmed and isolated.
I would highly, highly recommend Danna's rental for anyone, and I would definitely recommend it for anyone who is recuperating from a hospital stay. We certainly would have had no problem staying indefinitely!
A slice of Heaven on Earth! Love everything about this place!
Words cannot begin to convey the experience my daughter and I have had staying at this lovely VRBO! It is more than gorgeous, it is absolutely heaven. We have stayed here more than once, and every time, we are more than sad to leave. Danna is the perfect hostess, a gem and friend. She is helpful if you need anything, but gives you your freedom and privacy at the same time. She is an animal and nature lover, and can show and tell you the best trails all around the areas! These are trails that can be assessed just across the street from her house! They are breathtaking trails and we enjoyed them every day! Our collie was treated like a king at this VRBO, Danna greeted him as part of the family. The cottage is immaculate, with gorgeous bed linens and the ultimate pillows and towels. The decor is splendid - made so tasteful and elegant, yet very comfortable. We felt we were home here, truly home. The surroundings are so peaceful and the scenery - even as you look out the bedroom and living room windows is astounding. I would wake up each day rested and so excited to take on a new adventure. The sunlight fills the cottage and cool breezes often fill the bedroom at night. San Francisco and Half Moon Bay are not far - and there is a fun market and nice restaurants nearby. The Stanford campus is minutes away. It was a perfect location for us. Thank you so much, Danna, we will be back and we LOVE this slice of heaven on earth!
I wish I could live there. Seriously.
This is SO long overdue but I was just recommending this place to a friend, came on VRBO to get the link, and realized I'd neglected to write this! Sorry Danna!
I needed a place to finish my book. I had six weeks to go, needed to leave my home, husband, and kids, and just write the darn thing. I needed a place where I could eat, sleep, and write. I was desperate, and willing to take ANYTHING. What I found was a treasure, a gem, a magical existence, in the form of Danna Breen and her unique home and property. The bed was cozy, the kitchen had everything I needed, but unexpected was the view, the air, the energy, the wildlife, the vibe. A bluegrass band occasionally practices there. Sunset over the patio is breathtaking. The elderly in the community come by occasionally for BBQ. I'm telling you - you feel like a human thriving in the wilderness of humans at Danna's place and under Danna's care (always there when you need her, never hovering). I keep needing more writing getaways and I keep writing to Danna to see if the place is available. It never is. It's always booked. Speaks for itself.
Rates & Availability
Additional information about rental rates
Monthly rates negotiable by length of stay.


text: PTFE Spiral Wrap For Aircraft Industries - Industrial Equipment Classified Ads in West Chester In airplane, PTFE spiral wrap is used to cover the wiring and cables to make them secure from friction and any other damages. Tef-Cap Industries Inc manufactures excellent spiral wrap PTFE that is non-flammable, chemically inert and which is not affected by acids also. The company manufactures : Nylon and various colors spiral wrap which can perform better under temperature upto 500 F. Last Updated June 13, 2016 Category Industrial Equipment Location Park Valley Corporate Center 1155 Phoenixville Pike Suite 103, West Chester 19380, West Chester, Pennsylvania Show Map Website www.tefcap.com/ptfe-spiral-wrap/ More Info Find Industrial Equipment in West Chester PA Send Message Share This Classified With Your Social Networks Subscribe to this RSS Feed Keywords Location: Category: Report Ad Member Spotlight Chris Peters Warcraft Scrolls Public Relations Manager View Profile | Browse Other Members Business Spotlight Klassyweb Http://klassyweb.com View Profile | Browse Other Businesses

subset: commoncrawl


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Walker's campaign manager unloads from Politico
'It's a f---ing bitch, man,' Rick Wiley tells POLITICO of the Wisconsin governor's stunning collapse. Wisconsin Gov. Scott Walker pulled the plug on a bloated campaign that was headed into debt and was being undermined by furious donors, a warring staff and — at the root of it all — a candidate who was badly out of his league."


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This is the website for author, reporter and general writing enthusiast, Michael Farrell. In this space, Farrell features educated ramblings on topics such as sports, music, barroom adventure, and his return to the mean streets of western New York. He may also mention things about his novels "Running with Buffalo" or the recently released "When the Lights Go Out." Thanks for stopping by, and enjoy your scroll.
Friday, January 17, 2014
The Mark of St. Mary
1 comment:
- Chris Herzog said...
Hello Michael,
You've left an indelible mark on so many of us that graduated from St. Mary of the Lake. Your thoughts and memories are incredibly nostalgic for so many of us that we so proudly call ourselves the "Alumni of St. Mary's."
Please forgive me for the communication of your comments on WKBW Channel 7 this evening. I quoted you specifically from your writings of "The Mark of St. Mary" but the station unfortunately cut your name out of my interview.
You're words were so eloquently said…"The Diocese of Buffalo is eradicating a way of life that's formed many generations."
Michael, I graduated in 1979 the last of my family and the 1st in 1962. My husband and I have 4 sons of which our oldest graduated from St. Mary's 2 years ago and our 3 other sons are currently in 8th, 5th and 3rd grades.
Thank you for sharing your memoirs with all of us. Time may change but it never changes our times.
God Bless you Always!
Chris Herzog
- January 27, 2014 at 9:23 PM


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Yesterday on April Fools, I posted a joke thread that many deemed offensive. I am, and was aware that it was rather distasteful. I didn't mean to offend anyone, though I knew I would. I know it's really not a topic for humor, but I thought at least some of you would find it humorous. Well, my plan didn't work.
So I would like to apologize to anyone who was upset with that thread. It was not my intention to offend. I hope none of you took it personally.
For those of you who don't know what I'm talking about, the thread was a joke about rape.


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This is my new 6 element Yagi. Below it is my 10 element 2 metre beam, which now looks very small by comparison.
A few words of explanation. (few words? me? you are kidding!) On my Tenna mast I used to have a Vine 4/6m beam. That was 4 elements on 4metres, and 3 elements on 6meters. That was actually pretty good and it worked well because I have a restriction on the size of antenna I can have. It needs to be either maximum of 2 metres balanced across the mast, or shifted so that less than 1 metre extends on one side of the mast. So the Vine, which has a 2 metre long boom, was just fine. I could then lower it with the boom parallel to the ground. The 10ele worked too, as it is supported off centre and the short end is also less than 1 metre off to one side of the boom, so I could lower the mast IF the antennas were pointed just North of West.
I used to get annoyed about this as if I moved the mast I could use longer antennas, but is that really what I wanted to do? I really wanted a Tonna 9 element 2metre antenna, but with a boom just over 3metres it would not fit. However, I knew that I could do better than the 10 element, and in the end I bought a 6 element 2metre quad. That is a fine antenna, but I still felt restricted by the 2metre boom limit.
One day it finally dawned on me. The Vine was 2 metres by 3 metres (2m boom and 3m widest element.). But instead of 2x3 I could fit in 3x2. In other words, if I just had a 4metre beam instead of a 4/6metre dual band, it would only be 2m wide and could be 3m long in the boom (in fact any length of boom really). And a Tonna would then fit that way round!
This caused more head scratching. As the 4m beam I settled on, the Sandpiper one, has boom supports then the only thing I could fit under it was one other antenna. This would have to be the 2m one as the boom has to be pointing downwards when I lower it and thus a 6m would not fit (3m widest elements too long to fit). So for now I do not have a 6m antenna up. And the 2m quad no longer fits either.
Later I may put up a 6m vertical (I also have a 6m half wave vertical from Sandpiper).
So there you go. Lots of complicated stuff, but basically multiband 4/6m beam down, 2m quad down, 6ele 4m yagi up, 10ele 2m yagi up. Do I prefer this? Oh yes! Do I miss 6m --- yes.
OK, so the present antenna round down is
those two VHF yagis,
a 10/12m vertical dipole,
a 2m/70cms vertical and
a 4m vertical.
So far so good but I need to put something up for 6m. I have a Diamond 2 element (a sort of HB9CV) in the garage. that might go up soon.
If you are wondering why the 10element 2m went back up instead of the much wished for Tonna. Well, while I dithered Tonna stopped making them. Bah! Still, they may become available later. Maybe. Otherwise something better than the Diamond 10 element is due eventually.
Anybody want a used 4m/6m dual band yagi or a used 6 element 2m quad????


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|Use this URL to cite or link to this record in EThOS:
|Becoming simple and wise : the place of moral discernment in Dietrich Bonhoeffer's vision of Christian ethics
|Kaiser, Joshua Andrew
|Awarding Body:
|University of Edinburgh
|Current Institution:
|University of Edinburgh
|Date of Award:
|Availability of Full Text:
In this thesis I argue for the centrality of moral discernment in Dietrich Bonhoeffer's vision of Christian ethics. I contend that a close reading of his understudied Ethics manuscript, 'God's Love and the Disintegration of the World', not only reveals the importance of discernment, but also exposes a tension in his thinking between a simple, unreflective approach to God's will and a rational, reflective mode of moral deliberation. At several points in the 1930s and early 1940s, his emphasis on simplicity seems to preclude the very idea of moral reflection; however, a closer inspection reveals that the two are not mutually exclusive. I argue that Bonhoeffer's theology contains the necessary resources to incorporate, on Christological grounds, both simplicity and reflective moral deliberation into a coherent vision of moral discernment. Furthermore, I contend that this conceptual unity, premised on the relationship between Christ's two natures, becomes efficacious in the lives of Christians through a process of conformation to the form of Christ, which includes as an essential element the disciplined practice of spiritual exercises. Finally, drawing on Bonhoeffer's entire corpus, I investigate the theme of God's commandment, focusing in particular on simple obedience, and the concept of natural life, paying special attention to the shape of the created order. I conclude that simple obedience, while precluding self-centred moral reflection, nevertheless creates space for meditative reflection that understands reality through a Christological lens. In so doing, this meditative reflection finds its orientation in the natural, penultimate world, which serves as a crucial context and guide for those who want to become simple and wise.
|O'Donovan, Oliver. ; Nimmo, Paul.
|Not available
|Qualification Name:
|Thesis (Ph.D.)
|Qualification Level:
|EThOS ID:
|Not available
|Bonhoeffer ; Dietrich ; 1906-1945 ; Bonhoeffer ; discernment ; Christian ethics ; Christian formation ; theology


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Rhodomyrtus tomentosa (Aiton) Hassk, a representative specimen of the genus Rhodomyrtus and commonly known as rose myrtle, is an abundant flowering evergreen shrub growing in southern and southeastern Asia, particularly in southern China. It has been reputed for the medical uses of its leaves and the nutriceutical properties of the edible bell-shaped fruits. In traditional Chinese medicine, R. tomentosa has conventionally been served as a highly active agent to treat colic diarrhoea, dysentery, abscesses, haemorrhage, and gynecopathy.
Dr. Hongxin Liu and Haibo Tan from the Program of Natural Product Chemical Biology, headed by Prof. Shengxiang Qiu of South China Botanical Garden, conducted the systematic investigation on the leaves of R. toemtnosa with an aim to uncover natural products with novel structures and promising anti-MRSA activities, which resulted in the discovery of a series of hetero-dimer composed acylphloroglucinols with monoterpene (pinene-type: tementosenol A) or sesquiterpene (caryophyllene-type: tementodiones A-B and rhodomentones A-B) moieties. Absolute configurations of these novel compounds were determined by 1D and 2D NMR techniques and X-ray crystallographic analysis. It is noteworthy that tementosenol A and tomentosone C were found to exhibit potent antibacterial activity with a MIC value of 4.74 and 5.8 µM, respectively. Furthermore, in order to confirm the structure and obtain sufficient amounts of these new compounds for detailed biological evaluation and mechanic study,, total synthesis of these new compounds were also luanched and complished with success.. These results were published in RSC Advances (2016, 6, 25882-25886; 2016, 6, 48231-48236), Organic & Biomolecular Chemistry (2016, 14, 7354-7360), and Journal of Asian Natural Products Research (2016, 6, 535-541).
This project was funded by the National Science and Technology Major Projects of China (2014ZX10005002-005), National Natural Science Foundation of China (NSFC) (No. 81502949), Guangdong Province Science Natural Science Foundation of Guangdong Province (2015A030310482, 2016A030313149) and Technology Project (2016A010105015) .


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Don't start revving those engines just yet.
Yes, both houses of Congress have now passed legislation that would allow individual states to set highway speed limits.
The Senate bill differs in that the 55 mile-per-hour limit would still apply to buses and trucks. Such limits, though, would be repealed for passenger cars in both measures.


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Month-long state of emergency declared in Egypt
August 14, 2013 - 21:20 AMT
PanARMENIAN.Net - At least 95 Egyptians were killed on Wednesday, Aug 14, after security forces moved in on protesters demanding the reinstatement of President Mohammed Morsi, and the government imposed a state of emergency as violence swept the most populous Arab nation, Reuters reported.
Troops opened fire on Islamist demonstrators in clashes that brought chaos to the capital and other cities and looked certain to further polarize Egypt's 84 million people between those who backed Morsi and the millions who opposed his brief rule.
In the streets around the Rabaa al-Adawiya mosque in northeast Cairo, where thousands of Morsi supporters have staged a sit-in for the last six weeks, riot police wearing gas masks crouched behind armored vehicles, tear gas hung in the air and burning tires sent plumes of black smoke into the sky.
Several television stations ran footage of what appeared to be pro-Morsi protesters firing automatic rifles at soldiers from behind sandbag barricades.
Violence spread beyond Cairo, with Morsi supporters and security forces clashing in the cities of Alexandria, Minya, Assiut, Fayoum and Suez and in Buhayra and Beni Suef provinces.
The health ministry put the overall death toll at 95 people, including both police and civilians, with other sources saying at least 17 were killed in Fayoum province and five in Suez.
Morsi supporters besieged and set fire to government buildings and several churches were attacked, state media said.
The presidency announced a month-long state of emergency across Egypt and ordered the armed forces to help police enforce security. Rights activists said the move would give legal cover for the army to make arrests.
The interim cabinet, installed by the military to guide Egypt to fresh elections in around six months, also announced a curfew from 7 pm to 6 am in several provinces as well as Cairo and Alexandria.
Top stories
The Turkish government has investigated thousands of social media accounts and taken legal action against hundreds of them.
Meanwhile, New York has moved four places down the ranking to 13th position owing to a weakening of the US dollar in 2017.
According to a source, the Syrian army attacked several axes around Mesraba in a bid to overwhelm the Islamist rebels that defend the town.
Park Street, Calcutta's iconic restaurant and bar street, has at least three other buildings credited to Armenians.
Partner news
Latest news
Armenia's Gabriel Sargissian wins Sharjah Int'l Chess Championship The Olympic Champion collected eight points out of a possible nine to claim the champion's titled in the United Arab Emirates.
Relative calm on Karabakh contact line unchanged for one more week Overall, some 150 ceasefire violations - more than 1500 shots in total - by Azerbaijani army were registered in the past week.
Armenia revolution crushed Aliyev's plans to flaunt Cabinet reshuffle: expert Elites in Baku worried that any military activity on the line of contact would incur an international backlash, Zaur Shiriyev says.
Finland's president invited to visit Armenia At a meeting in the Georgian capital of Tbilisi, the two hailed the dynamically developing relations between Armenia and Finland.


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SJIWFF28 Presents: World of Web Series
Buy Tickets
Buy Festival Pass
This event will be held at NIFCO NOT The LSPU Hall.
Bring your web series ideas to life! From writing, funding, distribution, promotion and more, our experts can help direct you on how to launch your project, make it successful, and risks to avoid. Featuring Lisa Baylin (iThentic), Jenna MacMillan (Wharf Rats) […]


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3 Bedrooms
2 Full Bathrooms
Half Baths: 0
Single Family
Price: $225,000.00
AWESOME CAP COD RETREAT WITHIN WALKING DISTANCE TO INDIAN RIVER ACCESS. WALK TO THE BOAT RAMP AT THE END OF THE STREET IN THE COMMUNITY OF SANDY BEACH. Perfect for year-round or summer vacations. Get away from the crowd and still have access to all that this water community has to offer. Double doors access the brand new deck out front to enjoy the privacy of this small community and a spacious screened in porch for those summer and fall evenings. Upstairs there is a balcony off guest room to enjoy some down time and a Jack and Jill bathroom joins second guest room. Skylights offer ample light and style to this peaceful setting. Plenty of parking for family and guests. Bring your boat and fishing gear.
Price: $225,000.00
Waterfront: Waterview: None
Address: Sandy Beach
Building Name:
Dwelling Type: Single Family
Year Built: 1983
Waterview: None
Lot Dimensions:
Acreage: 0.35
Dwelling Sq Ft: 1100
Garage: None
Heating: Baseboard Electric
Cooling: Wall Unit
County Taxes: $265
City Taxes: $0
Water Fee: $0
Sewer Fee: $0
Association Fee: $200
Condo Fee: $0
Trash Fee: $0
Ground Rent: $0
Listing Broker: Re/Max Point Realty
Listing Agent: PAUL WEBSTER
Listing Status: Active
Copyright ©
2018 Lighthousehome.net
Delaware Web Design by Coastal Images Inc. for Beach-net.com


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When Georgios Papagiannis was selected with the No. 13 overall pick in the 2016 NBA Draft, the vast majority of the basketball world was stunned. In short, Papagiannis was not viewed as anything approaching a lottery pick prior to the selection process and, given that the Sacramento Kings were the team that pulled the trigger, the jokes were flying all over the place.
After less than two years with the organization, Papagiannis was waived on Thursday and, to put it plainly, it was an uncommon occurrence given the fact that most lottery picks do not see their contracts simply waived in this nature. Following the move itself, though, things got even more interesting, as Papagiannis' agent Marios Olympios had some very interesting comments about his client and the organization.
Olympios was reportedly speaking to a Greek radio station (via EuroHoops) when he criticized the Kings in swift fashion.
"He never got a chance by the Kings. He had a double-double every time he played in the G League. He had to travel for two and a half hours every time he was assigned to (Reno) and still he performed. There are many details that prove that he never got a real chance."


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It's easy for the wife to assume the worst when the husband suddenly becomes disinterested in sex. Is he having an affair? Does he not find you attractive anymore? Is your marriage over?
When actually, it could be none of those things.
Whether the man suffers from a complete lack of sex drive (lack of libido) or has just suddenly become no longer 'in the mood'. There are many reasons for this and many that can be easily treated.
It could be due to work related stress. If things at work are particularly tough this can spill out into the man's personal life, it can leave him tired and the pressure from work can begin to mount up and understandably, the last thing he wants to do at the end of a long day is to have sex.
Volume Pills Ingredients
The same can apply if he has personal issues or underlying problems that are unresolved and as a result, he doesn't feel like he wants to have sex with his wife. Whether this is to do with how he feels about her or possibly his sexuality is uncertain and the only way to find out for certain is to communicate with each other.
If there are no pressing issues that could cause the husband to shy away from sexual activity then there are other factors to consider. A testosterone deficiency, though this is extremely rare, this could explain a man's reluctance to have sex. Certain medications can also reduce a man's sex drive.
Seeing a physician could be an option if there are no real obvious causes as to why a man would suddenly lose his sex drive if there are no medical issues and he is in a happy marriage but there are many things that you can try first.
Eat healthy foods such as fruits and vegetables and cut down on the amount of fat you consume.
Get a proper amount of sleep – at least seven hours a night.
Get regular Exercise.
Get help to quit smoking.
If you drink heavily, cut down.
Consult a professional. A loss of libido could be a symptom of a serious medical condition.
Volume Pills Ingredients
Seek professional therapy to deal with your depression, inability to cope with stress, unresolved conflicts or anger management issues.
Talk with your wife about your sexual desire and any issues or concerns you may have.
Try to set aside quality time with your wife.
If your sexual orientation is an issue, be honest and upfront about this.
If all else fails, natural male sexual enhancement products like Performer5 can really be beneficial. With a powerful 100% natural herbal daily supplement designed to boost sexual performance, boost potency, virility, give you more stamina and impressive orgasms and ejaculations that go further and further. Performer5 will help to revitalise a flagging sex drive and restore the love life that you and wife once had.
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Natural Volume Pill Buying Guide
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When it comes to buying volume pills the number one product on the market is the Performer5 natural volume pills. These natural ejaculation improvement pills use only natural ingredients are 100% safe to use. You don't have to worry about any nasty side effects when you take these enhancement pills and you really will ejaculate more.
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Volume Pills
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Do they offer a money back guarantee and how long is this for
Do they have real testimonials for their products
Do they offer support and guidance
When it comes to natural volume pills the results you want to achieve is that you ejaculate more. With the Performer5 natural volume pills you will actually ejaculate up to 5 times more and you will enjoy amazingly satisfying orgasms each and every time.
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When it comes to choosing the right natural volume pills you need to assess your own lifestyle and the results you want. These volume pills won't just enhance your ejaculation they also increase your orgasm pleasure too. On top of this, your erections will be stronger and harder and you will have a lot more power. This will satisfy your sexual partner even more too.
Volume Pills
There are a lot of benefits to using Performer5 natural volume pills and these benefits can help to satisfy both partners. With such intense orgasms you will satisfy your partner each and every time. Your powerful ejaculations will also leave her begging for more. You will be the stud that you have envied in those porn films and your sexual partner will be only too happy to have sex anytime you want.
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A Bride Gift Tag Ornament
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Imagine how special it would be to receive a customized porcelain ornament with a personal saying, favorite artwork or even a photo of a loved one on it. Whether celebrating a special event or holiday, our porcelain ornaments make truly special gifts that will be remembered for years to come.
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Customize an ugly Christmas sweater designs by putting it on an ornament for a special gift for that newlywed, Mrs. or soon to be bride! Hang it off a present and the bride can then use it year after year!
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Here is the Dnipro Kids update from January that includes the Christmas events (they celebrate Christmas on January 7th).
There are some great photos of the kids enjoying themselves at their Christmas party, well worth a read.
Dnipro Kids Christmas Events can be seen HERE
The costs of all these Christmas events can be funded by one turnstile collection, so I'd like to ask again if anyone can spare some time on the 17th February to shake a bucket for a short time before the Hibs ve Aberdeen game. At the moment we are woefully short on volunteers for this game, and it makes a huge difference to our fundraising efforts if we can get a full quota of bucket shakers on the day.


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Research Topics
Genomes and Genes
Gene Symbol: Grin2a
Description: glutamate receptor, ionotropic, NMDA2A (epsilon 1)
Alias: GluN2A, NMDAR2A, NR2A, glutamate receptor ionotropic, NMDA 2A, GluRepsilon1, N-methyl D-aspartate receptor subtype 2A, glutamate [NMDA] receptor subunit epsilon-1
Species: mouse
Top Publications
Research Grants
Scientific Experts
Detail Information
Publications136 found, 100 shown here
- Unaltered pain-related behavior in mice lacking NMDA receptor GluRepsilon 1 subunitAndrei B Petrenko
Department of Cellular Neurobiology, Brain Research Institute, Niigata University, 1 Asahimachi dori, Japan
Neurosci Res 46:199-204. 2003..Although the contribution of other nociceptive pathways cannot be ruled out, we speculate that the preserved function of GluRepsilon 2-containing NMDARs could explain unaltered nociceptive behavior in mutant mice...
- Zinc alleviates pain through high-affinity binding to the NMDA receptor NR2A subunitChihiro Nozaki
Institut de Génétique et Biologie Moléculaire et Cellulaire, Illkirch, France
Nat Neurosci 14:1017-22. 2011..extracellular zinc modulates a plethora of signaling membrane proteins, including NMDA receptors containing the NR2A subunit, which display exquisite zinc sensitivity...
- Age-dependent reduction of hippocampal LTP in mice lacking N-methyl-D-aspartate receptor epsilon 1 subunitI Ito
Department of Biology, Kyushu University, Fukuoka, Japan
Neurosci Lett 203:69-71. 1996..The reduction was marginal at the age of 2-3 weeks, and became progressively prominent to adulthood, with the potentiation being 26% of that of the wild-type mice at 9-10 weeks...
- Synapse-selective impairment of NMDA receptor functions in mice lacking NMDA receptor epsilon 1 or epsilon 2 subunitI Ito
Department of Biology, Faculty of Science, Kyushu University, Fukuoka, Japan
J Physiol 500:401-8. 1997..5. These results suggest that NMDA receptors with different subunit compositions function within a single CA3 pyramidal cell in a synapse-selective manner...
- Functional characterization of a heteromeric NMDA receptor channel expressed from cloned cDNAsH Meguro
Department of Neuropharmacology, Brain Research Institute, School of Medicine, Niigata University, Japan
Nature 357:70-4. 1992..Furthermore, the heteromeric NMDA receptor channel can be activated by glycine alone...
- Cloning and expression of the epsilon 4 subunit of the NMDA receptor channelK Ikeda
Department of Neuropharmacology, Niigata University, Japan
FEBS Lett 313:34-8. 1992..The epsilon 4 subunit is thus distinct in functional properties from the epsilon 1, epsilon 2 and epsilon 3 subunits, and contributes further diversity of the NMDA receptor channel...
- Developmental changes in distribution of NMDA receptor channel subunit mRNAsM Watanabe
Department of Anatomy, Hokkaido University School of Medicine, Sapporo, Japan
Neuroreport 3:1138-40. 1992..In contrast, the zeta 1 subunit mRNA distributes ubiquitously in the brain throughout development. These findings suggest that changes in the subunit composition of the NMDA receptor channel take place during brain development...
- Reduced hippocampal LTP and spatial learning in mice lacking NMDA receptor epsilon 1 subunitK Sakimura
Department of Neuropharmacology, Niigata University, Japan
Nature 373:151-5. 1995..On the basis of the Mg2+ sensitivity and expression patterns, we have proposed that the epsilon 1 (NR2A) and epsilon 2 (NR2B) subunits play a role in synaptic plasticity...
- Modification of NMDA receptor channels and synaptic transmission by targeted disruption of the NR2C geneA K Ebralidze
Center for Learning and Memory, Massachusetts Institute of Technology, Cambridge 02139 4307, USA
J Neurosci 16:5014-25. 1996....
- Motor discoordination results from combined gene disruption of the NMDA receptor NR2A and NR2C subunits, but not from single disruption of the NR2A or NR2C subunitH Kadotani
Department of Biological Sciences, Kyoto University Faculty of Medicine, Kyoto 606, Japan
J Neurosci 16:7859-67. 1996..The NR1 subunit possesses all properties of the NMDA receptor-channel complex, whereas four NR2 subunits (NR2A-2D) potentiate and differentiate NMDA receptor responses by heteromeric assemblies with NR1...
- Importance of the intracellular domain of NR2 subunits for NMDA receptor function in vivoR Sprengel
Max Planck Institute for Medical Research, Department of Molecular Neuroscience, Heidelberg, Germany
Cell 92:279-89. 1998..Mice expressing the NR2B subunit in a C-terminally truncated form (NR2B(deltaC/deltaC) mice) die perinatally. NR2A(deltaC/deltaC) mice are viable but exhibit impaired synaptic plasticity and contextual memory...
- Increased thresholds for long-term potentiation and contextual learning in mice lacking the NMDA-type glutamate receptor epsilon1 subunitY Kiyama
Department of Molecular Neurobiology and Pharmacology, School of Medicine, University of Tokyo, Tokyo 113 0033, Japan
J Neurosci 18:6704-12. 1998..The mutant mice lacking the GluRepsilon1 subunit exhibited a reduction in hippocampal long-term potentiation (LTP), but a stronger tetanic stimulation ..
- PSD-95 promotes Fyn-mediated tyrosine phosphorylation of the N-methyl-D-aspartate receptor subunit NR2AT Tezuka
Department of Oncology, Institute of Medical Science, University of Tokyo, Minato ku, Tokyo 108 8639, Japan
Proc Natl Acad Sci U S A 96:435-40. 1999..Results showed that tyrosine phosphorylation of NR2A, one of the NMDA receptor subunits, was reduced in fyn-mutant mice...
- Hyperfunction of dopaminergic and serotonergic neuronal systems in mice lacking the NMDA receptor epsilon1 subunitY Miyamoto
Department of Neuropsychopharmacology and Hospital Pharmacy, Nagoya University Graduate School of Medicine, Nagoya 466 8560, Japan
J Neurosci 21:750-7. 2001..channels, are composed by assembly of the GluRzeta subunit (NR1) with any one of four GluRepsilon subunits (GluRepsilon1-4; NR2A-D). In the present study, we investigated neuronal functions in mice lacking the GluRepsilon1 subunit...
- Overexpression of motor protein KIF17 enhances spatial and working memory in transgenic miceRichard Wing Chuen Wong
Department of Cell Biology and Anatomy, Graduate School of Medicine, University of Tokyo, Bunkyo ku, Tokyo 113 0033, Japan
Proc Natl Acad Sci U S A 99:14500-5. 2002..Our results suggest that the motor protein KIF17 contributes to neuronal events required for learning and memory by trafficking fundamental N-methyl-d-aspartate-type glutamate receptors...
- Developmental loss of miniature N-methyl-D-aspartate receptor currents in NR2A knockout miceMatthew Townsend
Interdepartmental Neuroscience Program, Yale University, New Haven, CT 06520, USA
Proc Natl Acad Sci U S A 100:1340-5. 2003..NMDAR), long implicated in developmental plasticity, shows decay time kinetics that shorten postnatally as NR2A subunits are added to the receptor. Neither the mechanism nor immediate effect of this change is known...
- Locus-specific rescue of GluRepsilon1 NMDA receptors in mutant mice identifies the brain regions important for morphine tolerance and dependenceMakoto Inoue
Division of Molecular Pharmacology and Neuroscience, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki 852 8521, Japan
J Neurosci 23:6529-36. 2003..subunit of the NMDA receptor using mice lacking the gene encoding epsilon1 subunit of the NMDA receptor (GluRepsilon1-/- mice)...
- Impaired NMDA receptor-mediated postsynaptic function and blunted NMDA receptor-dependent persistent pain in mice lacking postsynaptic density-93 proteinYuan Xiang Tao
Department of Anesthesiology and Critical Care Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland 21287, USA
J Neurosci 23:6703-12. 2003..is expressed abundantly in spinal dorsal horn and forebrain, where it colocalizes and interacts with NMDAR subunits NR2A and NR2B...
- Enhancement of neurogenesis by running wheel exercises is suppressed in mice lacking NMDA receptor epsilon 1 subunitT Kitamura
Department of Biology, Graduate School of Science, Kyushu University, 6 10 1 Hakozaki, Higashi ku, Fukuoka 812 8581, Japan
Neurosci Res 47:55-63. 2003..These results suggest that the wheel exercise may activate NMDA receptors in the hippocampus, which in turn may enhance BDNF production and neurogenesis...
- Impaired long-term memory and NR2A-type NMDA receptor-dependent synaptic plasticity in mice lacking c-Fos in the CNSAlexander Fleischmann
Research Institute of Molecular Pathology, 1030 Vienna, Austria
J Neurosci 23:9116-22. 2003..This blockade was compensated in wild-type mice by NR2A-type NMDA receptor-activated signaling pathways, thus indicating that these pathways are compromised in c-..
- Intracellular domains of NMDA receptor subtypes are determinants for long-term potentiation inductionGeorg Köhr
Max Planck Institute for Medical Research, D 69120 Heidelberg, Germany
J Neurosci 23:10791-9. 2003..CA3-to-CA1 synapses of adult mice, different NMDAR subtypes with distinct functionality assemble from NR1 with NR2A and/or NR2B subunits...
- Behavioural adaptations to addictive drugs in mice lacking the NMDA receptor epsilon1 subunitYoshiaki Miyamoto
Department of Neuropsychopharmacology and Hospital Pharmacy, Nagoya University Graduate School of Medicine, 65 Tsuruma cho, Showa Ku, Nagoya 466 8560, Japan
Eur J Neurosci 19:151-8. 2004..formed by assembly of the GluRzeta subunit (called NR1 in rats) with any one of four GluRepsilon subunits (GluRepsilon1-4; NR2A-D), play an important role in excitatory neurotransmission, synaptic plasticity and brain development...
- Lack of NMDA receptor subtype selectivity for hippocampal long-term potentiationSven Berberich
Department of Molecular Neurobiology, Max Planck Institute for Medical Research, D 69120 Heidelberg, Germany
J Neurosci 25:6907-10. 2005NMDA receptor (NMDAR) 2A (NR2A)- and NR2B-type NMDARs coexist in synapses of CA1 pyramidal cells...
- Activation of NR2A-containing NMDA receptors is not obligatory for NMDA receptor-dependent long-term potentiationCarl Weitlauf
Center for Molecular Neuroscience, Vanderbilt University School of Medicine, Nashville, Tennessee 37232 0615, USA
J Neurosci 25:8386-90. 2005..One particular NR2 subunit, NR2A (NRepsilon1), has been proposed to play an integral role in LTP induction in the hippocampus and cortex...
- The nonkinase phorbol ester receptor alpha 1-chimerin binds the NMDA receptor NR2A subunit and regulates dendritic spine densityThomas J Van de Ven
Department of Pharmacology and Cancer Biology, Duke University Medical Center, Durham, North Carolina 27710, USA
J Neurosci 25:9488-96. 2005..phorbol ester receptor alpha1-chimerin is present in dendrites and spines, where it binds to the NMDA receptor NR2A subunit in a phorbol ester-dependent manner...
- The role of NMDAR subtypes and charge transfer during hippocampal LTP inductionSven Berberich
Department of Molecular Neurobiology, Max Planck Institute for Medical Research, Jahnstrasse 29, D 69120 Heidelberg, Germany
Neuropharmacology 52:77-86. 2007..For high frequency afferent stimulation (HFS), we found that genetic impairment of NR2A or pharmacological block of NR2A- or NR2B-type NMDARs can reduce field LTP...
- NMDA receptor subunit NR2A is required for rapidly acquired spatial working memory but not incremental spatial reference memoryDavid M Bannerman
Department of Experimental Psychology, University of Oxford, Oxford OX1 3UD, United Kingdom
J Neurosci 28:3623-30. 2008NMDA receptors (NMDARs) containing NR2A (epsilon1) subunits are key contributors to hippocampal long-term potentiation (LTP) induction in adult animals and have therefore been widely implicated in hippocampus-dependent spatial learning...
- NMDA receptor GluN2B (GluR epsilon 2/NR2B) subunit is crucial for channel function, postsynaptic macromolecular organization, and actin cytoskeleton at hippocampal CA3 synapsesKaori Akashi
Department of Cellular Neurobiology, Brain Research Institute, Niigata University, Niigata 951 8585, Japan
J Neurosci 29:10869-82. 2009..By immunohistochemistry, GluN2B disappeared and GluN1 (GluRzeta1/NR1) was moderately reduced, whereas GluN2A (GluRepsilon1/NR2A) and postsynaptic density-95 (PSD-95) were unaltered in the mutant CA3...
- Neurotoxic lupus autoantibodies alter brain function through two distinct mechanismsThomas W Faust
Burke Cornell Medical Research Institute, Department of Neurology and Neuroscience, Weill Medical College of Cornell University, White Plains, NY 10605, USA
Proc Natl Acad Sci U S A 107:18569-74. 2010..We have studied lupus AAbs that bind dsDNA and cross-react with the NR2A and NR2B subunits of the NMDA receptor (NMDAR)...
- Activation of extrasynaptic, but not synaptic, NMDA receptors modifies amyloid precursor protein expression pattern and increases amyloid-ß productionKarim Bordji
Unite Mixte de Recherche, Centre National de la Recherche Scientifique, Caen, France
J Neurosci 30:15927-42. 2010..Altogether, these data suggest that a chronic activation of extrasynaptic NMDAR promotes amyloidogenic KPI-APP expression leading to neuronal Aβ release, representing a causal risk factor for developing AD...
- Distinct modes of AMPA receptor suppression at developing synapses by GluN2A and GluN2B: single-cell NMDA receptor subunit deletion in vivoJohn A Gray
Department of Cellular and Molecular Pharmacology, University of California, San Francisco, CA 94143, USA
Neuron 71:1085-101. 2011..switch in synaptic N-Methyl-D-aspartate (NMDA) receptor subunit composition from predominantly GluN2B to GluN2A, though the precise role of this switch remains unknown...
- Evolution of GluN2A/B cytoplasmic domains diversified vertebrate synaptic plasticity and behaviorTomás J Ryan
Genes to Cognition Programme, Wellcome Trust Sanger Institute, Cambridge, UK
Nat Neurosci 16:25-32. 2013..shared ancestral functions and diversified subunit-specific functions, we exchanged the exons encoding the GluN2A (also known as Grin2a) and GluN2B (also known as Grin2b) CTDs in two knock-in mice and analyzed the mice's ..
- Molecular diversity of the NMDA receptor channelT Kutsuwada
Department of Neuropharmacology, School of Medicine, Niigata University, Japan
Nature 358:36-41. 1992..These findings suggest that the molecular diversity of the epsilon subunit family underlies the functional heterogeneity of the NMDA receptor channel...
- NMDA receptors interact with flotillin-1 and -2, lipid raft-associated proteinsCatherine Croft Swanwick
Laboratory of Neurochemistry, National Institute on Deafness and Other Communication Disorders, National Institutes of Health, Bethesda, MD 20892, USA
FEBS Lett 583:1226-30. 2009..Here we demonstrate interactions between the NR2A and NR2B subunits of NMDARs with flotillin-1 (flot-1), a lipid raft-associated protein...
- Distinct distributions of five NMDA receptor channel subunit mRNAs in the brainstemM Watanabe
Department of Anatomy, Hokkaido University School of Medicine, Sapporo, Japan
J Comp Neurol 343:520-31. 1994..These findings suggest that anatomical organization of the epsilon subunits is heterogeneous in various regions of the brainstem, which would give rise to functional diversity of the NMDA receptor channel in these regions...
- Long-trace interval eyeblink conditioning is impaired in mutant mice lacking the NMDA receptor subunit epsilon 1Y Kishimoto
Laboratory of Neurobiophysics, School of Pharmaceutical Sciences, The University of Tokyo, 7 3 1 Hongo, Bunkyo ku, Tokyo 113 0033, Japan
Eur J Neurosci 13:1221-7. 2001....
- NR2A but not NR2B N-methyl-D-aspartate receptor subunit is altered in the visual cortex of BDNF-knock-out miceElisa Margottil
Cognitive Neuroscience Sector, International School for Advanced Studies SISSA, Via Beirut, Trieste, Italy
Cell Mol Neurobiol 23:165-74. 20031. Aim of the present paper is to study the expression of N-Methyl-D-Aspartate receptor (NMDAR) subunits NR2A and NR2B within mouse visual cortex. 2...
- Specific assembly with the NMDA receptor 3B subunit controls surface expression and calcium permeability of NMDA receptorsKeiko Matsuda
Department of Developmental Neurobiology, St Jude Children s Research Hospital, Memphis, Tennessee 38105, USA
J Neurosci 23:10064-73. 2003..that NR3B, when exogenously introduced into hippocampal neurons, can coassemble with endogenous NR1 and NR2A and can reduce the Ca2+ permeability of NMDA currents...
- Long-term NR2B expression in the cerebellum alters granule cell development and leads to NR2A down-regulation and motor deficitsKatalin Schlett
Institute of Cell Biology and Immunology, University of Stuttgart, D 70569 Stuttgart, Germany
Mol Cell Neurosci 27:215-26. 2004..To analyze the importance of NR2B replacement by NR2C and NR2A subunits until the end of the first month of age, we generated mice with lasting NR2B expression but deficiency for ..
- Climbing-fibre activation of NMDA receptors in Purkinje cells of adult miceMassimiliano Renzi
Department of Pharmacology, University College London, Gower Street, London WC1E 6BT, UK
J Physiol 585:91-101. 2007..multiple NMDA receptor subtypes are indeed expressed in Purkinje cells of young and adult mice; in the adult, both NR2A- and NR2B-containing subtypes are present...
- Increased NR2A expression and prolonged decay of NMDA-induced calcium transient in cerebellum of TgDyrk1A mice, a mouse model of Down syndromeX Altafaj
Programa Gens i Malatia, Centre de Regulacio Genomica CRG, UPF, Parc de Recerca Biomédica de Barcelona PRBB, Barcelona, Spain
Neurobiol Dis 32:377-84. 2008..Transcriptome analysis showed an upregulation of the NR2A subunit of the NMDA type of glutamate receptors in TgDyrk1A cerebellum...
- Dysbindin regulates hippocampal LTP by controlling NMDA receptor surface expressionTina Tze Tsang Tang
Receptor Biology Section, National Institute of Neurological Disorders and Stroke, Section on Neural Development and Plasticity, National Institute of Mental Health, National Institutes of Health, Bethesda, MD 20892 3714, USA
Proc Natl Acad Sci U S A 106:21395-400. 2009..Imaging analyses revealed a marked increase in surface NR2A, but not NR2B, in hippocampal neurons derived from dysbindin-null mutant mice (Dys-/-)...
- Slitrk5 deficiency impairs corticostriatal circuitry and leads to obsessive-compulsive-like behaviors in miceSergey V Shmelkov
1 Howard Hughes Medical Institute, Ansary Stem Cell Institute and Department of Genetic Medicine, Weill Cornell Medical College, New York, New York, USA 2 These authors contributed equally to this work
Nat Med 16:598-602, 1p following 602. 2010..Thus, our studies identify Slitrk5 as an essential molecule at corticostriatal synapses and provide a new mouse model of OCD-like behaviors...
- Specific involvement of postsynaptic GluN2B-containing NMDA receptors in the developmental elimination of corticospinal synapsesTakae Ohno
Department of Physiology, School of Medicine, Teikyo University, Tokyo 173 8605, Japan
Proc Natl Acad Sci U S A 107:15252-7. 2010The GluN2B (GluRepsilon2/NR2B) and GluN2A (GluRepsilon1/NR2A) NMDA receptor (NMDAR) subtypes have been differentially implicated in activity-dependent synaptic plasticity...
- Postsynaptic alteration of NR2A subunit and defective autophosphorylation of alphaCaMKII at threonine-286 contribute to abnormal plasticity and morphology of upper motor neurons in presymptomatic SOD1G93A mice, a murine model for amyotrophic lateral sclerA Spalloni
Department of Experimental Neurology, Santa Lucia Foundation, 00143 Rome, Italy
Cereb Cortex 21:796-805. 2011..We show that presymptomatic SOD1(G93A) exhibit a selective decrease of NR2A subunit expression and of the alphaCa²(+)/calmodulin-dependent kinase autophosphorylation at threonine-286 in the ..
- D-amino acid oxidase knockdown in the mouse cerebellum reduces NR2A mRNAPhilip W J Burnet
Department of Psychiatry, University of Oxford, Warneford Hospital, Oxford OX3 7JX, UK
Mol Cell Neurosci 46:167-75. 2011..subunits, and found that DAO RNAi led to increased cerebellar D-serine levels (+77%), and decreased NMDAR subunit NR2A mRNA (-22%), but did not affect NR1 or NR2C mRNAs...
- Triheteromeric NR1/NR2A/NR2B receptors constitute the major N-methyl-D-aspartate receptor population in adult hippocampal synapsesClaudia Rauner
Department of Molecular Neurobiology, Max Planck Institute for Medical Research, Jahnstrasse 29, D 69120 Heidelberg, Germany
J Biol Chem 286:7558-66. 2011..function of synaptic NMDARs in postnatal principal forebrain neurons is typically attributed to diheteromeric NR1/NR2A and NR1/NR2B receptors, despite compelling evidence for triheteromeric NR1/NR2A/NR2B receptors...
- Short-term field stimulation mimics synaptic maturation of hippocampal synapsesElena E Bagley
Discipline of Pharmacology, University of Sydney, Sydney, Australia
J Physiol 590:1641-54. 2012..a developmental decrease in the probability of transmitter release (P(r)) and an increase in the contribution of GluN2A (NR2A) subunits to the NMDA receptor-mediated excitatory postsynaptic current (EPSC)...
- Dichotomy in the anxiolytic versus antidepressant effect of C-terminal truncation of the GluN2A subunit of NMDA receptorsDragos Inta
RG Animal Models in Psychiatry, Department of Psychiatry and Psychotherapy, Central Institute of Mental Health, Medical Faculty Mannheim, University of Heidelberg, Germany
Behav Brain Res 247:227-31. 2013..In line with this concept, ablation of the GluN2A subunit of NMDA receptors induces antidepressant and anxiolytic effects...
- Tolerance to ethanol intoxication after chronic ethanol: role of GluN2A and PSD-95Rachel A Daut
Laboratory of Behavioral and Genomic Neuroscience, National Institute on Alcoholism and Alcohol Abuse, NIH, Bethesda, MD, USA
Addict Biol 20:259-62. 2015The neural and genetic factors underlying chronic tolerance to alcohol are currently unclear. The GluN2A N-methyl-D-aspartate receptors (NMDAR) subunit and the NMDAR-anchoring protein PSD-95 mediate acute alcohol intoxication and ..
- Loss of GluN2A-containing NMDA receptors impairs extra-dimensional set-shiftingK Marquardt
Department of Neurosciences, University of New Mexico School of Medicine, Albuquerque, NM, USA
Genes Brain Behav 13:611-7. 2014..We have previously shown that constitutive deletion of GluN2A subunit in the mouse impairs discrimination and re-learning phase of reversal when exemplars are complex picture ..
- Channel-mediated astrocytic glutamate modulates hippocampal synaptic plasticity by activating postsynaptic NMDA receptorsHyungju Park
Mol Brain 8:7. 2015..Whether receptor-mediated glutamate release from astrocytes can regulate synaptic plasticity remains to be fully understood...
- Redox and trace metal regulation of ion channels in the pain pathwayJ Grayson Evans
Department of Anesthesiology, Neuroscience Graduate Program, University of Virginia School of Medicine, Charlottesville, VA 22908, U S A Department of Neuroscience, Neuroscience Graduate Program, University of Virginia School of Medicine, Charlottesville, VA 22908, U S A
Biochem J 470:275-80. 2015....
- Early Growth Response 1 (Egr-1) Regulates N-Methyl-d-aspartate Receptor (NMDAR)-dependent Transcription of PSD-95 and α-Amino-3-hydroxy-5-methyl-4-isoxazole Propionic Acid Receptor (AMPAR) Trafficking in Hippocampal Primary NeuronsXike Qin
From the Bloomfield Center for Research in Aging, Lady Davis Institute for Medical Research, Jewish General Hospital, and
J Biol Chem 290:29603-16. 2015..Our data indicate that Egr-1 is involved in NMDAR-mediated PSD-95 down-regulation and AMPAR endocytosis, a process important in the expression of long term depression. ..
- A family of photoswitchable NMDA receptorsShai Berlin
Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, United States
elife 5:. 2016..Photo-agonism of GluN2A or GluN2B elicits an excitatory drive to hippocampal neurons that can be shaped in time to mimic synaptic ..
- Female mouse fetal loss mediated by maternal autoantibodyLi Wang
Center for Autoimmune and Musculoskeletal Diseases, The Feinstein Institute for Medical Research, Northshore Long Island Jewish Health System, Manhasset, NY 11030, USA
J Exp Med 209:1083-9. 2012..A subset of these antibodies, present in 40% of patients, cross-reacts with the NR2A and NR2B subunits of the N-methyl-d-aspartate receptor (NMDAR)...
- [Different distribution of NMDA receptor subunits in cortex contributes to selective vulnerability of motor neurons in amyotrophic lateral sclerosis]Mei Zheng
Department of Neurology, Peking University Third Hospital, Beijing 100191, China
Beijing Da Xue Xue Bao 43:228-33. 2011..To investigate the relationship between different distribution of NMDA receptor subunits and motor neurons selective vulnerability in amyotrophic lateral sclerosis...
- Regulation of nuclear TDP-43 by NR2A-containing NMDA receptors and PTENMei Zheng
Department of Neurology, Peking University Third Hospital, 49 North Garden Road, Beijing, 100191, China
J Cell Sci 125:1556-67. 2012..We further demonstrate that activation of NR2A-containing NMDA receptors (NR2ARs) leads to PTEN downregulation and subsequent reduction of PTEN import from the ..
- Interaction between αCaMKII and GluN2B controls ERK-dependent plasticityFarida El Gaamouch
Universite de Caen Basse Normandie, CNRS UMR 6232, CINAPS PSY, 14 000 Caen, France
J Neurosci 32:10767-79. 2012..although synaptic activation in mouse cultured cortical neurons induces intracellular Ca(2+) elevation via both GluN2A and GluN2B-containing NMDARs, only GluN2B-containing NMDAR activation leads to a long-lasting ERK1/2 ..
- Optimal expression of cloned NMDAR1/NMDAR2A heteromeric glutamate receptors: a biochemical characterizationM Cik
Department of Pharmaceutical Chemistry, School of Pharmacy, London, U K
Biochem J 296:877-83. 1993The N-methyl-D-aspartate R1 (NMDAR1) and NMDAR2A subunits were expressed transiently either alone or in combination in human embryonic kidney (HEK) 293 cells...
- Molecular characterization of N-methyl-D-aspartate receptors expressed in mammalian cells yields evidence for the coexistence of three subunit types within a discrete receptor moleculeP L Chazot
Department of Pharmaceutical Chemistry, School of Pharmacy, London, United Kingdom
J Biol Chem 269:24403-9. 1994..These results show that the three NMDA receptor subunit types can co-assemble following their co-expression in mammalian cells with a pharmacological profile that is similar to that found for adult cerebellar NMDA receptors...
- N-methyl-D-aspartic acid receptor structure and functionC J McBain
Laboratory of Cellular and Molecular Neurophysiology, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland
Physiol Rev 74:723-60. 1994
- The NMDA receptor subunit 2B locus (Nmdar2b) maps to the distal end of murine chromosome 6A R Madarnas
Samuel Lunenfeld Research Institute, Mount Sinai Hospital, Division of Neurobiology and Molecular Immunology, Toronto, Ontario, Canada
Mamm Genome 5:115-6. 1994
- Chromosomal localization of the epsilon 1, epsilon 3 and zeta 1 subunit genes of the human NMDA receptor channelH Takano
Department of Neurology, Niigata University, Japan
Biochem Biophys Res Commun 197:922-6. 1993..By the fluorescence in situ hybridization, we mapped the genes for the epsilon 1, epsilon 3 and zeta 1 subunits of the human NMDA receptor channel to chromosomes 16p13, 17q25 and 9q34, respectively...
- Differential expression and co-assembly of NMDA zeta 1 and epsilon subunits in the mouse cerebellum during postnatal developmentM Didier
Laboratories for Molecular Neuroscience, McLean Hospital, Belmont, MA 02178, USA
Neuroreport 6:2255-9. 1995..The time course of their expression suggest, that these NMDA receptor subtypes may contribute to specific aspects of granule cell differentiation in the cerebellum...
- Regional and subunit specific changes in NMDA receptor mRNA and immunoreactivity in mouse brain following chronic ethanol ingestionL D Snell
Department of Pharmacology C236, University of Colorado Health Sciences Center, Denver 80262, USA
Brain Res Mol Brain Res 40:71-8. 1996..protein in the hippocampus and cerebellum (approximately 50% and 95%, respectively), and produces increases in the NR2A subunit protein in the hippocampus and cortex (approximately 25% and 40%, respectively)...
- Modified N-methyl-D-aspartate receptor subunit expression emerges in reeler Purkinje cells after accomplishment of the adult wild-type expressionM Watanabe
Department of Anatomy, Hokkaido University School of Medicine, Sapporo, Japan
Neurosci Res 26:335-43. 1996..The present results further indicate that the onset of the modified expression is subsequent to the establishment of synaptic connectivities in the cerebellum...
- Gene structure and chromosomal localization of the mouse NMDA receptor channel subunitsM Nagasawa
Department of Neuropharmacology, Niigata University, Japan
Brain Res Mol Brain Res 36:1-11. 1996..The murine chromosomal locations of the five NMDA receptor channel subunits, the epsilon 1 (Grin2a), epsilon 2 (Grin2b), epsilon 3 (Grin2c), epsilon 4 (Grin2d) and zeta 1 (Grinl) subunits, were determined using an ..
- Auditory pathway and auditory brainstem response in mice lacking NMDA receptor epsilon 1 and epsilon 4 subunitsY Munemoto
Department of Otolaryngology, Kansai Medical University, Osaka, Japan
Neurosci Lett 251:101-4. 1998..These results suggest a role for the NMDAR epsilon 4 in normal auditory functions while the NMDAR epsilon 1 may have a less critical function under normal conditions...
- Attenuation of focal ischemic brain injury in mice deficient in the epsilon1 (NR2A) subunit of NMDA receptorE Morikawa
Department of Neurosurgery, University of Tokyo Faculty of Medicine, Bunkyo ku, Tokyo 113 8655, Japan
J Neurosci 18:9727-32. 1998..To address this central issue of ischemic brain damage more directly, we used mutant mice deficient in the GluRepsilon1 (NR2A) subunit of NMDA receptor with or without additional heterozygous mutation in the GluRepsilon2 (NR2B) ..
- Maintenance of serotonin in the intestinal mucosa and ganglia of mice that lack the high-affinity serotonin transporter: Abnormal intestinal motility and the expression of cation transportersJ J Chen
Department of Anatomy and Cell Biology, Columbia University, College of Physicians and Surgeons, New York, New York 10032, USA
J Neurosci 21:6348-61. 2001..The watery diarrhea is probably attributable to the potentiation of serotonergic signaling in SERT -/- mice, whereas the transient constipation may be caused by episodes of enhanced 5-HT release leading to 5-HT receptor desensitization...
- Roles of the glutamate receptor epsilon2 and delta2 subunits in the potentiation and prepulse inhibition of the acoustic startle reflexT Takeuchi
Department of Molecular Neurobiology and Pharmacology, Graduate School of Medicine, University of Tokyo and CREST, Japan Science and Technology Corporation, Tokyo 113 0033, Japan
Eur J Neurosci 14:153-60. 2001....
- BDNF regulates spontaneous correlated activity at early developmental stages by increasing synaptogenesis and expression of the K+/Cl- co-transporter KCC2Fernando Aguado
Department of Cell Biology Faculty of Biology, and Barcelona Science Park, University of Barcelona, Barcelona 08028, Spain
Development 130:1267-80. 2003..Given that BDNF itself is regulated by neuronal activity, we suggest that BDNF acts as a homeostatic factor controlling the emergence, complexity and networking properties of spontaneous networks...
- Separable features of visual cortical plasticity revealed by N-methyl-D-aspartate receptor 2A signalingMichela Fagiolini
Neuronal Circuit Development, Institute of Physical and Chemical Research, RIKEN, Brain Science Institute, 2 1 Hirosawa, Wako, Saitama 351 0198, Japan
Proc Natl Acad Sci U S A 100:2854-9. 2003..The shortening of N-methyl-d-aspartate (NMDA) receptor currents by 2A subunit (NR2A) insertion has been proposed to delimit the critical period for experience-dependent refinement of circuits in ..
- Retention of NMDA receptor NR2 subunits in the lumen of endoplasmic reticulum in targeted NR1 knockout miceMasahiro Fukaya
Department of Anatomy, Hokkaido University School of Medicine, Sapporo 060 8638, Japan
Proc Natl Acad Sci U S A 100:4855-60. 2003..The NR1 gene deletion had no apparent effect on the levels of NR2A or NR2B mRNA but led to severe reductions of NR2A and NR2B protein in dendrites of CA1 pyramidal cells...
- Role of beta-catenin in synaptic vesicle localization and presynaptic assemblyShernaz X Bamji
Howard Hughes Medical Institute and Department of Physiology, University of California, San Francisco, San Francisco, CA 94143, USA
Neuron 40:719-31. 2003..This study defines a specific role for cadherins and catenins in synapse organization beyond their roles in mediating cell adhesion...
- Reduced sensitivity to ketamine and pentobarbital in mice lacking the N-methyl-D-aspartate receptor GluRepsilon1 subunitAndrey B Petrenko
Department of Anesthesiology, Niigata University School of Medicine, Japan
Anesth Analg 99:1136-40, table of contents. 2004..Functional NMDARs are composed by the assembly of a GluRzeta1 (NR1) subunit with GluRepsilon (GluRepsilon1-4; NR2A-D) subunits, which confer unique properties on native NMDARs...
- Phosphorylation state of postsynaptic density proteinsJ C Trinidad
Mass Spectrometry Facility, Department of Pharmaceutical Chemistry, University of California, 513 Parnassus Avenue, San Francisco, CA 94143, USA
J Neurochem 92:1306-16. 2005..This approach for the specific enrichment of phosphopeptides resulted in the identification of 42 phosphoproteins in the PSD preparation, 39 of which are known PSD components. Here we present a total of 83 in vivo phosphorylation sites...
- Roles of NMDA NR2B subtype receptor in prefrontal long-term potentiation and contextual fear memoryMing Gao Zhao
Laboratory of Higher Brain Functions, Institute of Neurobiology, Fudan University, 220 Han Dan Road, Shanghai 200433, China
Neuron 47:859-72. 2005..In particular, it has been suggested that NR2A-containing NMDA receptors are involved in LTP induction, whereas NR2B-containing receptors are involved in LTD ..
- Involvement of N-methyl-D-aspartate-type glutamate receptor epsilon1 and epsilon4 subunits in tonic inflammatory pain and neuropathic painMasanori Hizue
Discovery Biology Research, Nagoya Laboratories, Pfizer Global Research and Development, Pfizer Inc, Aichi, Japan
Neuroreport 16:1667-70. 2005..These results suggest that glutamate receptor epsilon1 and epsilon4 subunits are involved in tonic inflammatory pain and neuropathic allodynia, respectively...
- Obligatory role of NR2A for metaplasticity in visual cortexBenjamin D Philpot
Curriculum in Neurobiology, Neuroscience Center, and Department of Cell and Molecular Physiology, University of North Carolina, Chapel Hill, 105 Mason Farm Road, Chapel Hill, NC 27599, USA
Neuron 53:495-502. 2007..The decreased LTD/P threshold correlates with a decrease in the ratio of NR2A to NR2B subunits of cortical NMDA receptors (NMDARs) and a slowing of NMDAR-mediated excitatory postsynaptic ..
- NMDA receptor function and NMDA receptor-dependent phosphorylation of huntingtin is altered by the endocytic protein HIP1Martina Metzler
Centre for Molecular Medicine and Therapeutics, Child and Family Research Institute, Department of Medical Genetics, University of British Columbia, Vancouver, British Columbia, Canada V5Z 4H4
J Neurosci 27:2298-308. 2007..These findings may provide novel insights into the cellular mechanisms underlying enhanced NMDA-induced excitotoxicity in Huntington's disease...
- Signal pathways coupled to activation of neuronal nitric oxide synthase in the spinal cord by nociceptin/orphanin FQLi Xu
Department of Medical Chemistry, Kansai Medical University, 10 15 Fumizono, Moriguchi 570 8506, Japan
Neuropharmacology 52:1318-25. 2007..by the NR2B-selective antagonist CP-101,606; and the stimulated activity was observed in NR2D(-/-) mice, but not in NR2A(-/-) or NR2A(-/-)/NR2D(-/-) mice...
- Long-lasting NMDA receptor-mediated EPSCs in mouse striatal medium spiny neuronsStephen M Logan
Department of Physiology and Biophysics, Georgetown University School of Medicine, Washington, DC 20007, USA
J Neurophysiol 98:2693-704. 2007..slice preparations from postnatal day 6-8 (P6-8) and >P12 wild-type mice and mice that were lacking either the NR2A or the NR2C subunit of the N-methyl-D-aspartate (NMDA) receptor...
- Nicotine regulates multiple synaptic proteins by inhibiting proteasomal activityKhosrow Rezvani
Department of Neuroscience, Baylor College of Medicine, Houston, Texas 77030, USA
J Neurosci 27:10508-19. 2007..nicotine treatment increased the levels of the AMPA glutamate receptor subunit GluR1, the NMDA receptor subunit NR2A, the metabotropic receptor mGluR1alpha, the plasticity factor Homer-1A, and the scaffolding postsynaptic density ..
- Post-synaptic density-93 mediates tyrosine-phosphorylation of the N-methyl-D-aspartate receptorsY Sato
Department of Anesthesiology and Critical Care Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA
Neuroscience 153:700-8. 2008..density (PSD) -93, a member of the MAGUK family of proteins, interacts with the NMDA receptor subunits NR2A and NR2B as well as with Fyn, a member of the SFKs, in mouse cerebral cortex...
- Impaired maturation of dendritic spines without disorganization of cortical cell layers in mice lacking NRG1/ErbB signaling in the central nervous systemClaudia S Barros
Department of Cell Biology, Institute of Childhood and Neglected Disease, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA
Proc Natl Acad Sci U S A 106:4507-12. 2009..We conclude that ErbB2/B4-mediated NRG1 signaling modulates dendritic spine maturation, and that defects at glutamatergic synapses likely contribute to the behavioral abnormalities in ErbB2/B4-deficient mice...
- NR2A at CA1 synapses is obligatory for the susceptibility of hippocampal plasticity to sleep lossFabio Longordo
Department of Cell Biology and Morphology, University of Lausanne, CH 1005 Lausanne, Switzerland
J Neurosci 29:9026-41. 2009..We show that mild (4-6 h) sleep deprivation (SD) selectively augmented the number of NR2A subunits of NMDA receptors on postsynaptic densities of adult mouse CA1 synapses...
- Hippocampal NMDA receptor subunits differentially regulate fear memory formation and neuronal signal propagationCan Gao
Department of Psychiatry and Behavioral Sciences and The Asher Center for the Study and Treatment of Depressive Disorders, Chicago, Illinois, USA
Hippocampus 20:1072-82. 2010..Here we demonstrate, using intrahippocampal injection of subunit-selective compounds, that the NR2A-preferring antagonist impaired contextual and trace fear conditioning as well as learning-induced increase of the ..
- Involvement of NMDAR2A tyrosine phosphorylation in depression-related behaviourSachiko Taniguchi
Division of Oncology, Institute of Medical Science, University of Tokyo, Minato ku, Tokyo, Japan
EMBO J 28:3717-29. 2009..The NR2A subunit of the NMDA receptor is tyrosine-phosphorylated, with Tyr 1325 as its one of the major phosphorylation site...
- N-methyl-D-aspartate receptor subunit- and neuronal-type dependence of excitotoxic signaling through post-synaptic density 95Jing Fan
Graduate Program in Neuroscience, University of British Columbia, Vancouver, BC, Canada
J Neurochem 115:1045-56. 2010..Tat-NR2B9c, a membrane-permeant peptide that disrupts PSD-95/NMDAR binding, correlate with uncoupling NR2B- and/or NR2A-type NMDARs from PSD-95...
- NR3A-containing NMDARs promote neurotransmitter release and spike timing-dependent plasticityRylan S Larsen
Department of Cell and Molecular Physiology, University of North Carolina, Chapel Hill, North Carolina, USA
Nat Neurosci 14:338-44. 2011..Our findings indicate that NR3A relieves preNMDARs from the dual-activation requirement of ligand-binding and depolarization; the developmental removal of NR3A limits preNMDAR functionality by restoring this associative property...
- NMDA receptors in retrosplenial cortex are necessary for retrieval of recent and remote context fear memoryKevin A Corcoran
Department of Psychiatry and Behavioral Sciences, The Asher Center for the Study and Treatment of Depressive Disorders, Feinberg School of Medicine, Northwestern University, Chicago, Illinois 60611, USA
J Neurosci 31:11655-9. 2011..RSC-dependent context fear memory retrieval was mediated by NR2A, but not NR2B, subunit-containing NMDARs...
- Human N-methyl-D-aspartate receptor modulatory subunit hNR2A: cloning and sequencing of the cDNA and primary structure of the proteinR L Foldes
Allelix Biopharmaceuticals Inc, Mississauga, Ontario, Canada
Biochim Biophys Acta 1223:155-9. 1994..The hNR2A cDNA demonstrated an 88-89% nucleotide (nt) identity with the corresponding rodent cDNAs. The nt sequence of hNR2A would encode a 1464-aa protein that has a 95.2% identity with the rodent NR2A subunits.
- Functional correlation of NMDA receptor epsilon subunits expression with the properties of single-channel and synaptic currents in the developing cerebellumT Takahashi
Department of Neurophysiology, Institute for Brain Research, University of Tokyo, Japan
J Neurosci 16:4376-82. 1996....
- Chronic ethanol treatment produces a selective upregulation of the NMDA receptor subunit gene expression in mammalian cultured cortical neuronsX J Hu
Department of Pharmacology, University of Texas Health Science Center, San Antonio 78284 7764, USA
Brain Res Mol Brain Res 36:211-8. 1996..The altered NMDA receptor gene expression may be responsible for the observed upregulation of the NMDA receptor binding and function in the cortical neurons following chronic ethanol exposure...
- Biochemical evidence for the existence of a pool of unassembled C2 exon-containing NR1 subunits of the mammalian forebrain NMDA receptorP L Chazot
Department of Pharmaceutical and Biological Chemistry, School of Pharmacy, London, England
J Neurochem 68:507-16. 1997..M NaCl solubilised extracts yielded purification of the NR1 Mr 120,000 immunoreactive species, but no detectable NR2A or NR2B immunoreactivity...
- Conditioned eyeblink response is impaired in mutant mice lacking NMDA receptor subunit NR2AY Kishimoto
Laboratory of Neurobiophysics, School of Pharmaceutical Sciences, The University of Tokyo, Japan
Neuroreport 8:3717-21. 1997..To elucidate the roles of subunits NR2A and NR2C in motor learning, we investigated acquisition of the classically conditioned eyeblink response in a ..
- Attenuation of focal cerebral infarct in mice lacking NMDA receptor subunit NR2CH Kadotani
Department of Biological Sciences, Kyoto University Faculty of Medicine, Japan
Neuroreport 9:471-5. 1998..NR2C-deficient mice do not show impairment of motor coordination or motor learning. Therefore the development of drugs selectively inhibiting NR2C may prove beneficial in the treatment of stroke and traumatic brain injuries...
- Distribution and development of NMDA receptor activities at hippocampal synapses examined using mice lacking the epsilon1 subunit geneI Ito
Department of Biology, Faculty of Science 33, Kyushu University, Fukuoka, Japan
Neurosci Res 30:119-23. 1998..The LTP at the CA3 stratum oriens synapses was not significantly affected by the mutation at any age...
Research Grants1
- Neural Substrates of Contextual Regulation of ExtinctionKevin Corcoran; Fiscal Year: 2007..Understanding the neural mechanisms of contextual regulation of extinction could lead to more effective therapies for PTSD. [unreadable] [unreadable] [unreadable]..


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I must apologize. I certainly don't mean to update so infrequently and take so long to do it.
If I have any cops out there that read this, I have a question about guns, but I don't particularly want to post it for the whole internet community to see, and I don't want to ask the guys here in town that I know, because they'll know who I'm talking about. It's not something bag, at least I don't think it is. It's a question about legality of something.
Nothing exciting has happened since the 5th, that's why I haven't updated. Just work and life. And considering my work doesn't really produce anything exciting, it's not worth blogging about. I guess I could come on every day and say I went to work, it was an OK day, we made money. Not that I really have too many people reading (according to Blogger, I have one follower, and I know who she is), so I don't need to scare anyone away. I'd love to get more people to read, but I'd rather have them reading on their own free will, and I will not pump my blog full of random words just to get someone to notice me. But, I wonder if I posted a racy picture of me, would I get more hits??? Hmmm. That's ok, I don't need those.
But, I have been linked to from a cop blog. That's pretty huge if you ask me, especially since I'm under his links for VIP's. I mean, how cool does that make me sound? A lot cooler than I actually am, but oh well. I do have a link for him on the side bar, but I'm gonna pimp a link here as well. He's works at a juvenile hall, so if that interests you go here to read him.
It's summer (more or less), at least by the temperatures we've had lately, one would think so, when I walked to work today, one of the many temp signs I passed said 87 degrees. I may live in Iowa, but that's still a little warm to be considered spring temperature. And, of course, I'm dying to have a motorcycle ride. I hate that I haven't been on the back of a bike in over a year. And, since I work Thursday nights, I can't go to Porky's or Trophies in Des Moines, so I can't meet up with a certain guy that I know would take me on a little ride.
With it being warm, I'm supposed to be going on my walks, but I find it really hard to motivate myself to do that. One reason being my MP3 player's battery doesn't last over 3o minutes, I have been given my brothers' with all his music, but I know quite a few country songs that are great to walk to, that I can't listen to. Also, the last time I attempted my walk, I was too overzealous. I pushed myself way too much and barely made it through a quarter of it before I had to turn around and go home. Plus, as I learned today, with me not drinking pop, drinking water instead (which I don't drink near the amount as I did in pop), I'm not near as hydrated as I should be, and that leads to annoyances with the amount of exertion I put on myself and problems with dealing with the heat and sun.
All right, I've bored you enough for one night. But, I will try to update more often (though I wouldn't hold your breath on that if I were you).
Thursday, May 21, 2009
I feel summer creepin in and im Tired of this town again
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I *needed* some replacement metallic gel pens, so I went to Target where I picked them up the first time. Of course they didn't have th...
I went shopping today. I've been trying to be good and not shop (especially since I have a couple bigger shopping trips planned in the ...
Sunday: I made a couple birthday cards and a mini pocket letter Monday: I have to take 2 vacation days before they disappear on July 1st s...


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Contact Us
We specialize in molding your product for production. Quantities vary from a dozen pieces to several thousand depending upon your needs. With consistent quality and attention to detail.
For more information please contact us via email or phone.
Odyssey Metalworks
10415 Jitney Ln.
Grass Valley, CA 95945
Phone 530-273-5040
Fax 530-273-4794


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'Agent Carter' Season 2 Premiere Date Moved; Find Out Why It's Obama's Fault
Even Peggy Carter (Hayley Atwell) runs a little late sometimes. "Marvel's Agent Carter" Season 2 will no longer premiere on Tuesday, Jan. 5, 2016. Instead, the historical spy show will air on Tuesday, Jan. 19.
Why the delay? Blame Obama. Yes, really. President Barack Obama will be holding his State of the Union address on Jan. 12, TVLine reports. This address happens every year, but it's usually on the last Tuesday of January. The unexpected move forced ABC to preempt "Agent Carter." The network likely wants to air the season without interruptions, hence the two-week delay.
[SPOILER ALERT: Small spoilers about "Agent Carter" Season 2 are below.]
When Peggy makes her comeback, she'll be protecting the country from bad guys again, but this year she'll be in Los Angeles. The SSR sends her to the West Coast, where she'll run into bad guys like Madame Masque (Wynn Everett) and Joseph Manfredi (Ken Marino). She'll also have a new boss to fight with: Jack Thompson (Chad Michael Murray).
After taking credit for Peggy's actions in the Season 1 finale, the agent will be the new SSR leader. Despite Peggy basically being responsible for his promotion, he won't suddenly respect her. It sounds like Thompson will still be his usual rude self. "I think we're going to see some classic Thompson," Murray told TV Guide. "But we'll also get to peek behind some curtains and see a bit more."
Watch the "Agent Carter" Season 2 trailer below:
"Marvel's Agent Carter" Season 2 premieres Tuesday, Jan. 19, 2016 at 9 p.m. EST on ABC. The first episode will be two-hours.


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Java program for Windows or Mac OSX
Which Baggu, Catcoon? is a simple matching minigame I made in Processing as the final assignment in my Creative Programming Coursera class. It's based on a silly in-joke I have with friends. Basically, Catcoon is a cross between a cat and a raccoon with a "baggu" on his head. "Baggu" means bag, but any sort of container will do. You're given a situation and need to decide which baggu is most appropriate for Catcoon to wear.
There are random hints for each situation, but in the spirit of silliness most of them are humourous instead of helpful. When you make or miss a match, you're rewarded with an amusing success or failure image. You can also toggle between a bouncy or calming background song. The speed of the "meow" that plays when you click is randomized so that you get a variety of different meows to sound like different cats. The cursor is also a cat's paw.
My previous assignment was more algorithmic, so with this piece I wanted to focus on creating an interface and making a more cohesive game experience. I also wanted something whimsical and cute, so I tried to develop everything with that in mind.
I was debating between doing the artwork digitally or in watercolour, and in the end a hand/arm/shoulder injury made the decision of going with the latter automatic (less strain). This resulted in a more traditional media/handmade crossover look and feel. With the exception of the music, I recorded all of the silly sound effects.
Below are some work-in-progress screenshots of my attempts at laying out out the UI before illustrating.
- font is Mighty Zeo 2.0 by Blambot
- "bouncy" bgm is beat 008 by siakitty
- "calm piano" bgm is Piano Easy 1 by HojnyTomasz (sped up 2x with Maxim)


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Recommended operators
|UPSRTC - (Uttar Pradesh State Transport) R S Yadav Travels Shree Tara Travels
|Allahabad is the largest city located in Uttar Pradesh, and is the pilgrimage centre for Hindus. Formerly known as Prayag, this city holds Maha Kumbh Mela, the biggest human gathering in the world that takes place in every 12 yrs. Allahabad is the home of Sangam, means where three holy river Ganga, Yamuna and Saraswati meet. The city is also the leading learning center with having some finest institutes built across. Allahabad has produced some well known personalities like Harivansh Rai Bachachan, Motilal Nehru, Jawaharlal Nehru and few others. The city has a good shade of religion and culture. Few temples that are must visit like: Hanuman Temple, Patalpuri Temple, Alopi Devi Temple and Mankameshwar Temples. There are other few tourist places in Allahabad like: Triveni Sangam Allahabad, All Saints Cathedral, Khusro Bagh, Allahabad Museum, Ashoka Pillar and Alfred Park.
Buses from Allahabad
|Over 7 bus operators provide bus services on more than 651 routes from Allahabad with the maximum number of buses running from Allahabad to Banda. UPSRTC (UP Roadways) is the market leader in providing bus travel services from Allahabad, followed by UPSRTC - (Uttar Pradesh State Transport), R S Yadav Travels, Shree Tara Travels and Amar Travel. The most popular bus routes from Allahabad are Allahabad to Kanpur, Allahabad to Gorakhpur, Allahabad to Varanasi and Allahabad to Delhi. There is also a wide range of options available to consumers ranging from Volvo AC, Volvo AC Sleeper and AC Seater to Non-AC Sleepers and Non-AC Seaters.
Allahabad to Lucknow
34 Buses/Day
Allahabad to Delhi
27 Buses/Day
Allahabad to Nagpur
2 Buses/Day
Allahabad to Noida
10 Buses/Day
Buses to Allahabad
|There are 444 routes and 8 bus operators providing bus service(s) to Allahabad. There are maximum number of buses running to Banda to Allahabad, and the largest number of buses to Allahabad are operated by UPSRTC (UP Roadways). The top bus route(s) to Allahabad are Kanpur to Allahabad, Delhi to Allahabad, Varanasi to Allahabad and Agra to Allahabad. Top bus operators providing service to Allahabad are UPSRTC - (Uttar Pradesh State Transport), R S Yadav Travels, Vijayant Travels and Kalpana Holiday Travels. One can also avail of Volvo AC, Volvo AC Sleeper, AC Sleeper, AC Seater, Non AC Sleeper, Non AC Seater on Allahabad routes.
Lucknow to Allahabad
28 Buses/Day
Delhi to Allahabad
42 Buses/Day
Varanasi to Allahabad
19 Buses/Day
Nagpur to Allahabad
1 Buses/Day


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Jalapeno Bagels (Hardcover)
Currently not in store. Available to order. Usually Ships in 1-5 Days
For International Day at school, Pablo wants to bring something that reflects the cultures of both his parents -- Jewish and Mexican. When Pablo begins to help prepare the Sunday morning baking at his parents' bakery, he comes up with the perfect choice.


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Girl, whose proper name is SS, says it feels like it should be tighter. If she keeps feeling this, we may yet felt it a little. I'd also consider making it with a less stretchy yarn. I'd like to see how it would turn out in a cotton or linen, sized to fit more closely, not counting on the stretch of the fabric for the fit.
It was really nice to work a few rounds on socks this morning, and I did a whack of squares on the blanket. I calculated the size based on the 6 inch square size, and it seems I am a quarter done. Obviously, less than I thought, and it is time to bust my buns. I'm not working it together as I go. I don't mind the putting together later, for the same reason I didn't mind working in all the ends on the scarf. It feels just like embroidery to me!
As I worked on the scarf last night, I did have a wave of longing for an embroidery needle and some linen, or even cotton fabric. It has nothing to do with the tea towels Mary Maxim has in its catalogue, which it probably always had, but I never noticed before. (Of course I would not use the paints, but do them in the way it was done when I was a girl, like this.) It has nothing to do with checking out Nordic Needle for the first time in a while. It has nothing to do with the fact that they carry things like this or this , and even this . And then there is the Blackwork , that I am wanting to try.
No it's not that at all.
I'll have to do some before vacation to take the edge off.


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Watch Your Step
Today I am grateful for the blueberry pancakes Sam made for dinner last night and for the power of gratitude practice done regularly.
This seems like an appropriate post today as we head into a rainy morning and also as we wrap up a winter that included ice, snow, and mud as well.
It is the most recent "Gratitude Flow" column I write for the local newspaper.
Watch Your Step
It's the time of year where both ice and mud can lead to treacherous and messy steps. Ice requires slowing down and being cautious. It also requires our full attention. Full attention—that is what I try to give to each moment, or each hour. It helps us experience life on a deeper level; not just passing our days but participating in them as well.
Giving anything our full attention can seem like a challenge in our world today, with so many things pulling us in different directions. Ice reminds us of our priorities—taking the next step safely if we are on foot, or turning the next corner slowly if we are driving. Salt and sand can make it safer to move on ice, but speed is still not recommended. Pausing to practice gratitude during our day is like slowing down on ice. We are reminded of our priorities and we give more attention to what is right in front of us.
Mud offers different challenges. It can really weigh a person down, make things slippery, and be a mess to clean up. Not to mention that we can get stuck in it. Mud can usually be avoided by taking a different route or accommodated for by wearing boots. Self-pity and self-defeating thoughts are like mud. They catch us in a negative thought pattern and mire us in the muck of ungrateful feelings. Ingratitude can be avoided by keeping up a steady stream of appreciation for the gifts in our daily lives. Gifts as basic as morning coffee or a banana to eat. Gifts as profound as waking up to a new day and being able to get out of bed.
We can't avoid all of life's slippery slopes and messy times, but we can make choices that put us in a better position to stay upright, limit physical and emotional injuries, and come out the other side still feeling hopeful and able to find gratitude.
When I think of watching my step, a couple other ideas come to mind. If you were fortunate enough to grow up on a farm, like I was, watching your step went with the territory when you left the house yard for the cow yard. Having to watch our step and sometimes landing where we didn't want to was far outweighed by the more pleasant and interesting things we got to witness and learn about as farm kids. The fresh air and open spaces to explore and run in, when not icy or muddy, were wonderful blessings of farm life.
Watching your step as you walk, run, skate, ski or take part in any other physical activity is just good common sense. Even so, falls and trips can happen. It's part of life and being active. It's worth the risk. Consider what other healthy choices in your life are worth the risks and the work required. Pursue them patiently.
Watching your step is also about slowing down to notice what is happening around us and in our minds and hearts. It is a gratitude practice in and of itself. As I take a step, I think about these facts: my legs and feet work with minimal pain or discomfort; I have shoes to wear and they are of good quality to protect my feet and the rest of my body; I can see where I am going and enjoy the indoor and outdoor scenery; and I feel safe and secure where I walk as opposed to worrying about criminals, terrorists, or getting caught in the crossfire between warring factions. Many people around the world don't have shoes to wear, don't feel safe when they step outside, may be malnourished and unable to walk far. It puts things in perspective for me really quickly.
You will probably still catch me complaining about the ice and mud, or other types of troubles and messes that life sends our way from time to time. But I guarantee you that I complain less when I practice gratitude more. And I easily find things to be grateful for when I do something as basic as watching my step.


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Radisson Blu Scandinavia Hotel, Gothenburg
Radisson Blu Scandinavia Hotel, Gothenburg
Radisson Blu Scandinavia Hotel, Gothenburg
Radisson Blu Scandinavia Hotel, Gothenburg
Stay at our fabulous city center hotel
Book a room at Radisson Blu Scandinavia Hotel, Gothenburg and stay within walking distance of great attractions such as the Gothenburg Museum of Art (called Göteborgs Stadsmuseum) and the Casino Cosmopol Gothenburg. Our city center location places you right across the street from excellent shopping at Nordstaden Mall, as well as Central Station, which makes it easy to explore this beautiful city.
Modern AmenitiesIn addition to a prime location, our hotel features sophisticated style with modern services. Each of our 349 rooms and suites includes amenities such as minibars and free high-speed wireless Internet. Enjoy a delicious breakfast in bed or a relaxing dinner in privacy and comfort with our 24-hour room service. We also offer an upscale dining experience on-site at the Atrium Bar & Restaurant.
Hotel makeover in progressOur Scandinavian hotel is going through an exciting makeover. All of our rooms are ready for check-in. The refurbishment continues with other part of the hotel during 2018.
Follow our progress and new look every step of the way. Watch our short video to see one of our hotel rooms being transformed.
Event venuesIf you're traveling for business and need a convenient meeting venue, you're in the right place. Choose between our 16 conference rooms, suitable for corporate events as well as social gatherings. Among the rooms is a large banquet hall that can house up to 500 attendees; the beautiful lobby accommodates up to 1,000 guests.
At a Glance
City Center Attractions
Walk to prime shopping, museums, gardens and visit the popular Liseberg Amusement Park from the Radisson Blu Scandinavia Hotel, Gothenburg.
Stylish Rooms
Each of the 349 hotel rooms includes modern amenities such as free high-speed, wireless Internet and sophisticated design.
Atrium Bar & Restaurant
Sample Swedish cuisine for breakfast, lunch or dinner, and order tasty cocktails or snacks at the bar.
24-hour Room Service
Enjoy delicious meals and snacks around the clock from the comfort of your hotel room, compliments of our 24-hour room service.
Indoor Parking
Feel secure when parking in our on-site, indoor garage, or take advantage of valet parking.
16 aesthetic conference rooms
Host a high-powered board meeting or a grand gala in one of our 16 exquisite meeting spaces.
Gothenburg has the honour of welcoming the competing teams in the Volvo Ocean Race - the toughest sailing race in the world. Everyone is invited to be part of the adventure and the celebration! Radisson Blu is an Official Partner to Volvo Ocean Race.READ MORE
Stay for a good night's sleep or enjoy a delicious dinner while your car recharges for free with Tesla Destination Chargers.READ MORE
New Meeting Facilities
Plan your next conference with us and enjoy our newly renovated meeting facilities.READ MORE
Follow our hotel makeover.READ MORE


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Ask About This Home
Spacious townhouse located in Spring Lakes offers low maintenance living. Amenities include swimming pool, tennis courts, walking trails, club house with exercise and meeting rms. Kitchen with stainless steel appliances has access to the rear deck and has a pass through to the dining rm. Gleaming HW floors in both the great and dining rms. An electric stone faced corner fireplace adds charm and warmth to the great rm. First floor master BR has a vaulted ceiling, his and her closets, and master bath with double vanity, separate shower, and garden tub. Second level features 2 large BRs and bonus rm with unfinished walk-in storage areas. Conveniently located to I 64/81, and historic downtown.