text:
Designing the Ideal Stent
Stent cell geometry and its clinical significance in carotid stenting.
By Mark H. Wholey, MD, and Ender A. Finol, PhD
Balloon-expandable closed-cell stents were introduced for carotid artery stenting (CAS) as early as 1995. At that time, the cell structure of these stents was intended to support tissue and plaque against the vessel wall. This provided the necessary scaffolding for the stented carotid artery, as it did for the coronary or other peripheral arterial stenotic lesions (Figure 1). The postprocedure angiograms demonstrated the precision in which these stents restored the vessel to its normal dimension. Unfortunately, there was a 2% incidence of stent collapse.1 The stainless steel stent, when placed lower than the level of the mandible, could be externally compressed. For these reasons, the balloon-expandable stent for carotid occlusive disease was largely abandoned. Several valuable lessons, however, were learned from those early studies. Not only were radial rigidity and scaffolding important design features, but a range of expansion became a necessity. In the absence of articulation in the early designs, the flexibility and high profile of the stents prevented easy trackability. To improve the flexibility and the trackability, a connecting bridge between the two stents was integrated into the design (Figure 2). It was then observed that, depending on the length of the bridge, plaque prolapse could occur at the site. This observation would prove to be critical as we moved to the newer designs.
When the noncrushable memory alloy nickel titanium (NiTi) stent was introduced, there were already several established design improvements. Flexibility, trackability, device profile, and security were essential for the delivery system. The stent design concept included vessel conformability, scaffolding, side branch preservation, visibility, and recoil control to minimize migration and foreshortening. To evaluate expansion and prolapse analysis, tests were designed to measure the flexion (ie, radial forces) that could occur under controlled pressure.
More recently, the question of indications, advantages, and limitations of an open-cell design versus a closed-cell stent has generated significant debate. As background, the Precise (Cordis Endovascular, a Johnson & Johnson company, Miami, FL) and Acculink (Abbott Vascular, Santa Clara, CA) devices are open-cell stent designs, whereas the carotid Wallstent and NexStent (Boston Scientific Corporation, Natick, MA) and Xact stent (Abbott Vascular) devices are closed-cell designs; this concept will be discussed further later in this article. Bosiers et al2 reported their observations in a retrospective dual-center study of 701 patients undergoing CAS with a binary categorization of open- or closed-cell stents. They indicate a stroke and death rate of 1.4%. When transient ischemic attacks (TIAs) were included, the total stroke, death, and TIA event rate was 3.7%; 4.6% was obtained in symptomatic patients and 3.7% in asymptomatic patients (Table 1).2 In the open-cell–designed stents, there was an 11.1% stroke, death, and TIA event rate versus 3% in closed-cell stents. TIAs were largely responsible for the difference in outcomes. When TIAs were excluded, open-cell stent patients had 1.6% events versus 0.9% for the patients with closed-cell stents (Table 2).2
As even the investigators recognized, there are limitations to retrospective studies. For example, 74% of these patients received the carotid Wallstent; therefore, operator familiarity may have played a role. As might be expected, data from other retrospective reviews have provided different results. Recently, another retrospective analysis of more than 700 patients reported by Reimers et al3 indicated that there were no statistically significant outcome differences at 30 days. Yet, numerically, the open-cell Precise outperformed all other stents. In addition, statistically significant results were obtained showing superiority of open-cell stents for restenosis at 1 year.4 Also, in a comparative study of 3,000 patients enrolled in the CAPTURE postmarket surveillance study, using the open-cell Acculink stent with the Accunet filter, a stroke and death event rate of 5.7% was described.5 The EXACT trial, using the closed-cell Xact stent and Emboshield filter, described a stroke and death rate of 5.1% (Table 3).6 The difference between the open-cell Acculink and the closed-cell Xact stent stroke and death rate was not statistically significant. In another US postmarket study—the CASES-PMS trial with the open-cell Precise stent—all stroke and death at 30 days was measured at 4.5%.7 Finally, in an analysis of 203 of our most recent patients at the Pittsburgh Vascular Institute who had an average 10.3-month follow-up and had undergone CAS with the Acculink stent and the Accunet (Abbott Vascular) filter, 1.6% presented restenosis; there was a 1% incidence for all strokes, 1% for myocardial infarction events, and a 7.8% all-deaths event rate. Although this is also retrospective and a small sample size, it does add to the debate of what plays a role in stent-related emboli.
The conflicting data and resulting debates raise important questions regarding cell size, surface area coverage, and the overall identification of the important factors in pre- and postperiprocedural embolic events. Clinical outcomes relating to any stent design are a function of performance attributes, such as axial and circumferential stiffness and strength, scaffolding properties, conformability, and side branch preservation. Stent designers attempt to balance such long-term performance attributes along with more acute considerations relating to deliverability and deployment, such as constrained profile and flexibility. All of these attributes must be balanced appropriately given the anatomical challenges and dynamic forces exerted by the vessel on the stent. Designers must select and optimize among numerous interrelated parameters, such as strut length and width, wire diameter and pitch, bridge configuration, material selection, and processing conditions to achieve optimal performance.
Consider radial force as an example of the difficulty of assessing a performance attribute in stent design. The radial force required will be dependent on lesion characteristics and location. Aorto-ostial lesions may require more force than internal carotid artery stenoses. The radial strength of a carotid stent should provide adequate apposition and enough resistive force to prevent vessel wall recoil. Excessive force or rigid closed-cell designs might result in plaque disruption in a vulnerable unstable lesion. Most nitinol stents can be adjusted for cell size and still maintain satisfactory radial force.
As a result, given the aforementioned engineering considerations, it is important to anticipate that binary classifications, such as "open" versus "closed," may be too general for meaningful retrospective clinical analysis, especially when multiple varied stent designs are pooled within these two broad classifications. Reflecting on the comparative studies available, cell size and surface area coverage appear to be important. Whether open or closed may be less important than the actual cell size. For example, a closed cell with a diameter of 1,000 µm is more likely to be responsible for plaque prolapse and embolization than an open cell of 500 µm. Typically, the number and arrangement of bridge connectors differentiate open-cell designs from closed-cell designs (Figure 3). If adjacent ring segments are connected at every possible junction, the design is typically classified as closed cell. In closed-cell designs, these connections usually take the form of flexible bridge connectors, allowing some limited degree of flexion between adjacent rings (Figure 4). If some or all of the connecting junction points are removed, the design is typically classified as open cell. Such a design inherently allows for more flexion between adjacent rings, because fewer connection points allow for greater flexion and conformability. The flexion benefits of an open-cell design have a cost in scaffolding uniformity, just as the scaffolding benefits of a closed-cell design have a cost in flexion and conformability.
Many stent designs have been tried in clinical practice, with varying results. It is tempting to interrogate these results on the basis of binary attributes such as open cell versus closed cell, or one-dimensional attributes such as wall thickness or cell size. Such analyses may be misleading, however, because of ambiguous definitions of these characteristics, or other important and often interrelated design characteristics that may not be considered. Open- versus closed-cell stent comparison serves as a good example of a chief analysis because it is entirely possible to design an open-cell stent with a cell size smaller than that of a closed-cell stent, thus rendering the distinction near meaningless. Similarly, a braided-wire stent and nitinol stent might both be classified as closed-cell, but they effectively share no meaningful design attributes. In stent design, just as in clinical investigations, single variables often suggest some meaningful insight, but we must be mindful that outcomes are driven not by single variables, but rather an interrelated system of variables.
As mentioned earlier, anatomy too plays an important role. If there are complex angulations at the carotid bifurcation where trackability becomes an issue, the flexibility of open-cell design may be required knowing that the potential of plaque prolapse will exist (Figure 5A). Reducing the size of the open cell, however, can control plaque prolapse. When cells open on the concave surface of an angulated carotid bifurcation, they are prone to having prolapse and fish scaling on the open surface (Figure 5B). This scaling can result in intimal disruption with contrast extending to the adventitia (Figure 5C). The struts in the open-cell configuration can penetrate the intima and on occasion can extend to the adventitia. This raises the question of predisposition to restenosis or stent fracture at this site (Figure 6). Stretching of the cell size is exaggerated in the bend. There are, however, open-cell stents that meet the criteria of small cell size with cell conformability during flexion and consequently have acceptable scaffolding. Cell-size stability will prevent prolapse and possibly decrease embolic events in the long term. This in itself is important in that 20% of periprocedural events are in the poststenting period. This also explains the >2% stroke event (ipsilateral) in the 30-day versus 1-year stroke incidence noted in essentially all of the trials.
With the recent introduction of intravascular ultrasound with virtual histology, it may be possible to better understand these lesion characteristics in determining the significance of cell size, stent flexibility and conformability, plaque prolapse, and thrombotically active plaque, all of which are stroke predictors. The angiographic anatomy may provide a better understanding of lesions more demanding of flexibility or scaffolding, whereas intravascular ultrasound with virtual histology might suggest lesions that are thrombotically active and not suited for stenting regardless of cell design (Figure 7).
It is not unreasonable that the cell structure, in itself, can be designed to act as its own filter. With virtual histology and the possibility of having a better understanding of the lesion characteristics, we may be better able to choose the most appropriate stent. Early clinical experience with the helically designed stents has also demonstrated excellent flexibility and kink resistance. The helical design allows uniform cell size at flexion points without scaling. In terms of clinical applications, the calcified and tortuous lesion may be best suited to the more conformable open- or helical-designed stents. For vulnerable plaque or ulcerative lesions with type C characteristics (high anatomical risk), greater scaffolding might be more appropriate.
It is clear that there remain unresolved clinical issues and room for improved product designs. While we await more robust data sets and device evolution, it is important that the interventional community remain mindful of the lessons of recent clinical trials in the US and Europe. The CAPTURE study observed that a difference existed between inexperienced versus experienced operators.8 Major stroke and death occurred in 3.4% in the lesser-experienced operators versus a 1.1% event rate in the operators with significant experience. Furthermore, an all-stroke and death rate comparison of inexperienced operators versus experienced operators also showed a difference with a 6.9% event rate with inexperienced operators versus a 4.6% rate in the high-level operators. Higher experienced operators had a 0% death rate, whereas inexperienced operators had a 2.3% death rate. The lesson is that doctors can and do achieve excellent stenting results when they are well trained in their devices and the procedure and select patients appropriate for the procedure.
The desired features of a carotid stent would include scaffolding that is adequate enough to control plaque prolapse but has acceptable levels of flexibility, conformability, and radial strength to track to the lesion, appose the vessel wall, and control recoil. Of course, no matter how tight the scaffolding, there is still no stent available to control embolic particles 100 µm and smaller. These small particles constitute most of the emboli produced during CAS. When used with an efficient distal protection filter and combined with a flow-reversal system, we may be able to control at least most of the embolic events occurring periprocedurally. Delayed postprocedure events, however, remain an enigma.1
The authors thank Roseanne R. Wholey for her assistance with the preparation of this article.
Mark H. Wholey, MD, is from the UPMC Shadyside Hospital and the Pittsburgh Vascular Institute, Pittsburgh, Pennsylvania. He has disclosed that he is a consultant to Cordis, Abbott (Guidant), Medrad, Boston Scientific, Edwards Lifesciences, and Mallinckrodt. Dr. Wholey may be reached at (412) 623-2083; email@example.com.
Ender A. Finol, PhD, is an Associate Research Professor from Carnegie Mellon University, Institute for Complex Engineered Systems and Biomedical Engineering Department, Pittsburgh, Pennsylvania. He has disclosed that he holds no financial interest in any product or manufacturer mentioned herein. Dr. Finol may be reached at (412) 268-1841; firstname.lastname@example.com.


text:
Text of the current Articles of Association, as last amended by the General Meeting of 11 January 2016.
This site uses cookies to send you advertising and services in line with your preferences. Continuing browsing to consent to the use of cookies. To learn more or opt out of all or some cookies click here.

subset: commoncrawl


text:
Monnalisa Bebe girls t-shirt and legging set has pink background with pink roses print. The main body of the t-shirt is 95% cotton, with a necklace effect print with heat sealed crystal embellishment, round neck and puffed sleeves. It has a floaty viscose inset of fabric at the back and a button opening at the back. The leggings are stretch cotton with elasticated waist.
Please see our Delivery & Returns Policy for full information
Payment & Security - Please contact us for information
Payment: All payments via Sagepay
Upon receiving your order we carry out a standard pre-authorisation check on your payment card to ensure there are sufficient funds to fulfil the transaction. Goods will not be dispatched until this pre-authorisation check has been completed. Your card will be debited once the order has been accepted.


text:
KatieDCDowntownerCover, originally uploaded by AreaGuides.com Network.
Local Mount Vernon teenager Katie Sargent is featured on the cover of the DC's Downtowner this week. Katie just finished her junior year at Mount Vernon High School, MVHS, where she is an honors student in the International Baccalaureate, IB, program. Katie is captain of the MVHS cross country team, as well as being on the varsity swim and soccer teams. Katie has coached youth soccer with Gunston Microsoccer and is a swim coach at Mansion House Club for the past several years as well. Katie began modeling a year ago after winning several honors at the International Modeling and Talent Association, IMTA, event in New York last summer. She is headed to Los Angeles this summer to model for Vision LA and is represented by CH Models, Randy Cazz and Joey Hunter, out of New York. Katie recently placed second in the State of Virginia in the category of Impromptu Speech, is also representing Mount Vernon High School and the State of Virginia in the Future Business Leaders of America, FBLA, National Speech Competition being held in Anaheim the end of June as well. Also see Katie on USCute.com


text:
Hi my names wayne and I'm 27, I live in kent and Military history has always been something I'm interested in as I have a relative who fell at vimi ridge during WW1. I am very interested in getting involved in looking for relics, but I want to do it in the right way without hacking anyone off and getting in trouble. I have been in the armed forces myself so I have respect for what potentionaly can be found, and what not to mess around with.
I would appreciate any advice shared.


text:
Words that start with cholerhe
Found 1 words that start with cholerhe. Browse our Scrabble Word Finder, Words With Friends cheat dictionary, and WordHub word solver to find words starting with cholerhe. Or use our Unscramble word solver to find your best possible play! Related: Words containing cholerhe
- Scrabble
- Words With Friends
- WordHub
- Crossword


text:
By Columbia Threadneedle Investments Global Asset Allocation Team
Overall, we remain neutral - but the threat of temporary market tantrums has raised the bar on portfolio risk management.
Our overall asset allocation position remains neutral with some scope for above-neutral equity beta. The trend of gradual appreciation in overall asset prices with temporary tantrum-style setbacks remains in place. The overarching framework for monetary policy appears to be undergoing a dovish overhaul - no rate move in September, a more gradual path implied by the Fed's dot plots and language suggesting that the concept of neutral has moved lower. Then again, last month's market tantrum revealed the insidious risk of simultaneous drawdown across asset classes that can result from even the smallest shift in a hawkish direction. The tantrum threat raises the bar on portfolio risk management. Explicit hedges, as well as surveillance of harbingers of elevated tantrum risk should be introduced to overall portfolio strategy.
Equity: Overall, we remain neutral. Full equity sensitivity remains appropriate, but last month's dovish adjustment by the Fed should keep the reflation theme intact. We expect some improvement in earnings over the balance of the year, resulting from a stable U.S. dollar exchange rate and recovering oil prices.
Within equity allocation: We do not have strong and consistent geographic preferences. We continue to prefer emerging markets over developed markets from a valuation standpoint. We remain moderately overweight emerging market equities, while we have reduced developed market equities from neutral to moderately underweight. We remain neutral U.S. equities, with small caps remaining moderately overweight following prolonged underperformance, model upgrades and the possibility of an economic and earnings trough.
Fixed income: Overall, we remain neutral. Duration tools remain neutral. The helpful portfolio construction dynamic of negative correlation to risk assets was interrupted by last month's tantrum, but in a low-growth, low-inflation environment, we expect this dynamic to reassert itself.
Within fixed-income allocation: A benign environment leaves us mostly neutral. While spreads remain tight, we do not detect an impulse for widening. We are modestly overweight investment-grade bonds and modestly underweight securitized bonds. High yield remains neutral after strong year-to-date performance. We remain neutral Treasuries, while we have increased TIPS to moderately overweight. We expect CPI inflation to move sharply higher in the coming months, and TIPS have a tendency to outperform when this occurs. We remain neutral non-U.S. government bonds. Evidence has strengthened that gilts are overpriced and may be a source of funding for overweighting other countries.
Alternatives: We are reducing our recommended allocation to alternatives to modest overweight. Overall, the concept of expanding our diversifying components remains irresistible, but the weak performance of alternatives during the September tantrum is troublesome, since our thesis relies upon an incremental diversification benefit from alternatives. We can still modify our tactics within alternatives to suit the special circumstances of today's market environment.
Within alternatives allocation: Commodities remain moderately overweight. Momentum and carry dynamics remain favorable, and commodities offer a dimension of diversification in our risk asset holdings. Absolute return strategies also remain moderately overweight. The efficacy of active, market-neutral and systematic strategies is struggling, possibly due to investor appetite for passive investments. To help with tantrum-specific risk management, we can add a long-volatility position either when pricing becomes favorable or in the context of a strategy with deliberate attention to managing carry cost.
Currency: For the Japanese yen and British pound, we have moved from moderately underweight to neutral. Currency tools provide a mixed message. A weaker U.S. dollar would be most compatible with our preference for emerging market equities and commodities, but an explicit weak dollar view might be redundant. Also, going long the U.S. dollar has been a useful component of a tantrum hedge strategy. Even so, we remain underweight the euro, as European assets are likely perceived as unattractive, with banks struggling across the region and political uncertainty rising in the fourth quarter.
Disclosure: None.
© 2016 Columbia Management Investment Advisers, LLC. All rights reserved.
With respect to mutual funds and Tri-Continental Corporation, investors should consider the investment objectives, risks, charges and expenses of a fund carefully before investing. To learn more about this and other important information about each fund, download a free prospectus. The prospectus should be read carefully before investing.
Investors should consider the investment objectives, risks, charges, and expenses of Columbia Seligman Premium Technology Growth Fund carefully before investing. To obtain the Fund's most recent periodic reports and other regulatory filings, contact your financial advisor or download reports here. These reports and other filings can also be found on the Securities and Exchange Commission's EDGAR Database. You should read these reports and other filings carefully before investing.
The views expressed are as of the date given, may change as market or other conditions change and may differ from views expressed by other Columbia Management Investment Advisers, LLC (CMIA) associates or affiliates. Actual investments or investment decisions made by CMIA and its affiliates, whether for its own account or on behalf of clients, may not necessarily reflect the views expressed. This information is not intended to provide investment advice and does not take into consideration individual investor circumstances. Investment decisions should always be made based on an investor's specific financial needs, objectives, goals, time horizon and risk tolerance. Asset classes described may not be suitable for all investors. Past performance does not guarantee future results, and no forecast should be considered a guarantee either. Since economic and market conditions change frequently, there can be no assurance that the trends described here will continue or that any forecasts are accurate.
Columbia Funds and Columbia Acorn Funds are distributed by Columbia Management Investment Distributors, Inc., member FINRA. Columbia Funds are managed by Columbia Management Investment Advisers, LLC and Columbia Acorn Funds are managed by Columbia Wanger Asset Management, LLC, a subsidiary of Columbia Management Investment Advisers, LLC.
Columbia Threadneedle Investments is the global brand name of the Columbia and Threadneedle group of companies.
NOT FDIC INSURED · No Bank Guarantee · May Lose Value


text:
Netflix Reports Slower Speeds for Verizon
Posted by Andre Tauladan in Net Neutrality, netflix, Verizon on Wednesday, February 19, 2014
Whether Verizon throttles Netflix' service or not (see "The Post-Net Neutrality Era - Does Verizon Shape Netflix and Amazon?" - here), recent ISP speed ranking by Netflix (see "Netflix - New Site Shows ISP Performance for US, UK, Scandinavia and more" - here) shows a clear degradation for Verizon's FIOS and DSL services since September-October 2013 to January 2014:
See also "Brazil, Chile
This entry was posted on Wednesday, February 19, 2014 at 6:30 AM and is filed under Net Neutrality, netflix, Verizon. You can follow any responses to this entry through the RSS 2.0. You can leave a response.


text:
View Single Post
July 30th, 2011, 06:05 PM
Name: Andy
Join Date: July 27, 2011
Location: CA
Age: 23
I voted 'yes', because based on my own personal experience it has mattered significantly, and not always in a good way. If size truly didn't matter then anyone on here would be fine with having a one inch penis, which is something I seriously doubt anyone would admit. It also matters because it's possible to be too big; I've had a number of experiences where it was too painful for the girl I was with and one time we even had to stop half way through. Again, in that situation, my size certainly mattered. Is size ALL that matters? Of course not. I'd say if you're average and up (or even a little below average) you'll be fine as long as you know how to use it and read your partner's body well. But realistically, I'd have to say that ultimately size does matter.


text:
This movie is about a group of people who get trapped in a Supermarket after a Tsunami hits the coast of Queensland, Australia. But they soon find out that they have more to worry about than being in a flooded grocery store, there's 12 foot sharks swimming around them, and it's hungry. Written by Michael Hallows Eve
A video game developer's world spirals out of control when his shape-shifting indestructible virtual creation becomes all too real.
PREDESTINATION chronicles the life of a Temporal Agent sent on an intricate series of time-travel journeys designed to ensure the continuation of his law enforcement career for all eternity. Now, on his final assignment, the Agent must pursue the one criminal that has eluded him throughout time. Written by Anonymous
Blade finds himself alone surrounded by enemies, fighting an up hill battle with the vampire nation and now humans. He joins forces with a group of vampire hunters whom call themselves the Nightstalkers. The vampire nation awakens the king of vampires Dracula from his slumber with intentions of using his primitive blood to become day-walkers. On the other side is Blade and his team manifesting a virus that could wipe out the vampire race once and for all. In the end the two sides will collide and only one will come out victorious, a battle between the ultimate vampire whom never knew defeat, facing off against the greatest vampire slayer. Written by jay
As shark-infested storms grow stronger and more complex, the world braces for the inevitable - a global sharknado. This year, the mission gets personal for chainsaw-wielding leader Fin Shepard and his bionic wife, April, when their young son gets trapped in a sharknado and is transported all over the world. Written by Happy_Evil_Dude
Elliot Moore is a high school science teacher who quizzes his class one day about an article in the New York Times. It's about the sudden, mysterious disappearance of bees. Yet again Nature is doing something inexplicable, and whatever science has to say about it will be, in the end, only a theory. Scientists will bring out more theories, but no explanations, when a more urgent dilemma hits the planet. It begins in Central Park. Suddenly and inexplicably, the behavior of everyone in the park changes in a most bizarre and horrible way. Soon, the strange behavior spreads throughout the city and beyond. Elliot, his wife, Alma, and Jess, the young daughter of a friend, will only have theories to guide them where to run and where to hide. But theories may not be enough. Written by J. Spurlin
The legendary Power Rangers must stop the evil space pirate Divatox from releasing the powerful Maligore from his volcanic imprisonment on the island of Muranthias, where only the kindly wizard Lerigot has the key to release him. The hope of victory lies in the Ranger's incredible new Turbo powers and powerful Turbo Zords. Written by Andrew N. [email protected]
A futuristic love story set in a world where emotions have been eradicated. Written by Nathan Parker
Having discovered they could turn animals invisible, a group of scientists test the subject on a human. Head of research, Dr. Sebastian Caine decides to use himself as the subject. After the experiment can't be reversed, it takes a toll on Caine's personality, causing him to hunt down and kill his colleagues
King Roland of the planet Druidia is trying to marry his daughter Princess Vespa to Prince Valium, but Vespa is kidnapped by the evil race of the Spaceballs. The Spaceballs ask Roland a tremendous ransom: all the air of Druidia (you see, the air of Spaceball had serious pollution problems...). The King decides to offer a generous amount of money to a space rogue, Lone Starr, to persuade him to save Vespa. What follows is the parody of a _LOT_ of famous SF movies. Written by Flavio Rizzardi [email protected]
An underwater earthquake cracks open a crater deep beneath the ocean's surface unleashing a prehistoric predator. On the sleepy island of White Sands, local teens drink and party beside a beach bonfire. One of them wanders off after a pretty girl and disappears, leaving only a severed hand behind. Written by Deeww
Brilliant and obese scientist Sherman Klump invents a miraculous weight-loss solution. After a date with chemistry student Carla Purty goes badly, a depressed Klump tries the solution on himself. Though he instantly loses 250 pounds, the side effects include a second personality: an obnoxiously self-assertive braggart who calls himself Buddy Love. Buddy proves to be more popular than Sherman, but his arrogance and bad behavior quickly spiral out of control. Written by Jwelch5742
Vegeta is lured to the planet New Vegeta by a group of Saiyan survivors in hopes that he will be the king of their new planet. But when he finds that they have ulterior motives of universal domination, he and the Z Warriors must fight Broly, the legendary Super Saiyan. Written by page8701
Los Angeles and other cities around the world are being bombarded by meteors that seem to be slowing down once they hit the earth's atmosphere. The earth is suddenly being invaded by space aliens that have landed off the shore of LA, and who begin killing everybody along the beach. The military is ordered into action. Marine Staff Sergeant Nantz (Aaron Eckhart), who was about to retire, is reassigned to a new platoon. The platoon, flown by chopper to the forward operating base at Santa Monica Airport, is being led by a new 2nd Lt. Martinez (Ramon Rodriguez). They are sent on a mission to rescue some civilians who are trapped at the police station within alien territory. They only have 3 hours to complete their mission and get out before the Air Force bombs that zone. Written by Douglas Young (the-movie-guy)


text:
Bayview Bay Apartments
Bayview Bay is a comfortable 3-star hotel set 1.9 km from Harbour Town Gold Coast and 7 km from Sea World.
The hotel allows quick access to palm trees and a harbour.
The non-smoking rooms at Bayview Bay come with climate control, a safe, a balcony, a microwave and a work desk. Some rooms at Bayview Bay have a view over the sea. In-room self-catering facilities include a dishwasher, coffee/tea makers and a washing machine.
Guests can dine at Mano's Kitchen located within 10 minutes' walk away.
Coolangatta/Gold Coast airport is 35 minutes' drive away from Bayview Bay.
The property features parking, a vending machine and a lift.
Bayview Bay pampers guests with an outdoor swimming pool, barbeque grills and a golf course.


text:
Gynecological Surgical Oncologist Staff Physician
- Employer
- The University of Arizona Cancer Center/Dignity Health St. Joseph's Hospital and Medical Center
- Location
Phoenix, Arizona
- Salary
- Competitive salary and generous benefit package
- Posted
- May 25, 2017
- Closes
- Jul 25, 2017
- Position
- Gynecologic Oncologist, Medical Oncologist
- Education
- BC/BE Medical Oncologist, DO, MD
- Hours
- Full Time
Gynecological Surgical Oncologist Staff Physician
Dignity Health St. Joseph's Hospital and Medical Center, in partnership with the University of Arizona Cancer Center (UACC), is seeking a Board-certified/Board-eligible Surgical Oncologist experienced in the management of patients with Gynecological cancer conditions such as cervical, endometrial, ovarian, peritoneal, tubal, vaginal and vulvar cancers.
This position will be employed by the Dignity Health Medical Group and report to the Chair for Obstetrics and Gynecology. The Surgical Oncologist will participate in the development of a Gynecologic oncology program for our growing NCI-designated comprehensive cancer program. Responsibilities include working with the Chair to build and cultivate professional community relationships, ensure the growth of the clinical patient care program, participate in the NRG Oncology and cooperative group studies and the implementation of a clinical trial research program. The candidate should have a strong interest in cancer prevention or treatment research and be prepared to participate in the establishment of a clinical trials program under the direction of the Chair and in collaboration with the UA Deputy Director, the VP, Oncology Services Dignity Health AZ and the UA Director for Research Administration.
- M.D. or D.O.
- AZ Medical License,
- Board certified or Board eligible for specialty
- Clinical trial experience
- Teaching experience
- Acceptable references from supervisor, peer, and subordinate; from a registered nurse; and from a research mentor
- Willing to abide by and promote the values of Dignity Health SJHMC and the UA.
The University of Arizona Cancer Center at Dignity Health St. Joseph's recently moved into a new 220,000-square-foot outpatient cancer center on the Phoenix Biomedical Campus in the heart of downtown Phoenix, Arizona. St. Joseph's Hospital and Medical Center is the location of the Oncology Inpatient Unit and is approximately 2 miles away. SJHMC is a 571+ bed, not-for-profit hospital that is consistently recognized as an outstanding place to work and one of Arizona's healthiest employers.
The University of Arizona Cancer Center has been designated by the National Cancer Institute as an NCI- Comprehensive Cancer Center, the NCI's highest designation. This designation is reserved for centers focusing on patient care as well as research, prevention, education, outreach and training.
We are offering a competitive salary with immediately active incentive plans, and a generous benefits package.
If interested, please send a cover letter and CV, along with any related letters of recommendation to:
John Staren at email@example.com
Similar jobs


text:
Best Choice Products Height Adjustable Standing Desk Monitor Riser Gas Spring | 36″ Tabletop Sit to Stand Workstation
Best Choice Products presents this standing desk. Elevate your work flow. Our standing desk creates a healthy work space allowing you to balance between sitting down and standing up. The 2-tier design features a monitor tabletop and a keyboard drawer. Ergonomic and innovative, this adjustable standing desk features a smooth, gas-spring lift mechanism with 8
(as of 10:44 am ADT - Details) + Add To Wish List


text:
Why doesn't mySQL allow users@'%' from localhost?
Talik asked:
It seems that the solution to accepting users from localhost is to create a copy of the user with @'localhost' (in addition to user@'%'). I'm trying very hard to understand the logic here, because it seems kind of bat-nuts crazy that the 'any host' wildcard, '%', wouldn't also accept localhost connections. Creating a second user isn't very practical when dealing with a large number of users. If a user changes their own password, it would then leave the other one unaffected.
Is there any sort of workaround to allowing user@'%' to accept localhost connections?
My answer:
You need to remove the anonymous users, as MySQL's pattern matching will match them first.
Run the
mysql_secure_installation script or remove them manually.
View the full question and answer on Server Fault.
This work is licensed under a Creative Commons Attribution-ShareAlike 3.0 Unported License.


text:
So here is my opinion. . .I'm not a huge soup fan at the best of times, and if I am eating soup, i prefer the creamy kinds. For this recipe, cut out the cumin. I followed the recipe, except that. . .
*instead of parsnips I added potatoes
*I added a little bit of cinnamon and sugar to sweeten it a bit
*sour cream is a good topper!
Otherwise, my hubby and family gobbled it up! So feel free to give it a try with recommendations from our home to yours!
Monday- Chicken Milani and garlic bread (I've posted this one before, so see previous posts for a link!)
Tuesday-Carrot Ginger Soup, croissants (w/ turkey and Swiss cheese)
Wednesday-Sausage and Perogies, cut up veggies
Thursday (CP)-Cranberry Chicken or Cranberry Roast, rice pilaf, corn and peas
Friday (OAMC)-Chicken Enchiladas (already made in the freezer!), salad
Saturday's snack-Cappuccino Chip Muffins (see below)
Sunday (BFS)-Pancakes and bacon
Cappuccino Chip Muffins
This recipe came from my sister's roommate (I believe)back in the day (thanks Laura!) Pam was great at making treats for when I came to visit or when she came to visit me, and this is one that I loved--but you HAVE to eat them fresh. They grow somewhat dry if they sit around, so i wouldn't recommend making a big batch. My sister would always make them "Costco-like." You know, with the tops popping over and bigger than the bottoms? For some reason, that makes a muffin just that much better to me! :) I believe this came from a recipe book of her roomie that had 10 or less ingredients per recipe. Or maybe it was 5 or less steps in a recipe. I don't know anymore. Have no clue what the book is. I just like the muffins.
2 c. flour
1/2 c. sugar
1T. baking powder
1T. instant coffee
1/2 t. cinnamon
1 c. milk
1 egg
1/2 c. vegetable oil
1/2 c. semi sweet chocolate chips
Preheat oven to 375F. Grease a 12 c. muffin pan. In a bowl, stir together first 5 ingredients. In another bowl, beat milk, egg and oil. Add to flour mixture until just combined. Mix in chocolate chips. Place in muffin pan--fill to the top. Bake for 18-20 minutes.
Serves: 8-12 muffins
Many more MPM at http://www.orgjunkie.com/


text:
Your Life A to Z Recipe: Friday, September 5th, 2014: Vegetable Tofu Miso Soup, Autumn Kale Salad, Cumin Roasted CarrotsPosted: Updated:
Vegetable Tofu Miso Soup
Yield: 6-8 servings
2 Liters Water
¾ Cup Miso
3 Tbsp. Dashi
½ Cup Onion, Chopped
½ Cup Fennel, Chopped
½ Cup Chanterelle Mushrooms
½ Cup Carrots, Chopped
½ Cup Green Onion, Chopped
1 Cup Kale
1 Cup Tofu, Chopped
1 Tbsp. Ginger
1 Tbsp. Garlic
1 Tbsp. Soy Sauce
1 Tbsp. Mirin
1 Tbsp. Rice Wine Vinegar
1 Tbsp. Chili Flakes
Sweat all vegetables in a sauce pan with the chili flakes, garlic and ginger. Add
dashi, miso, rice wine vinegar and mirin. Add water and bring to a boil. Garnish
with tofu and serve.
Autumn Kale Salad
Yields: 6 Servings
3 Cups Kale
1 Cup Pancetta Bacon
1 Cup Herbed Pecans (recipe to follow)
2 Asian Pears, Sliced
¾ Cup Huckleberries
2 Oz. Sherry Vinegar
½ Cup Maple Syrup
1 Sprig Rosemary
¾ Cup Crows Dairy Black Pepper Feta
Heat a sauté pan over medium heat, add pancetta and render the fat. Once pancetta is nice and crispy add the herbed pecans and the rosemary. Deglaze the pan with Sherry vinegar using all the pan drippings to create the Dressing. Lastly fold in maple syrup; this will help bind the dressing. Remove dressing from heat and allow to cool slightly. In a bowl place the chopped kale, add the huckleberries and Asian pears and serve.
Herbed Pecans
Yields: 1 Cup
3 Tbsp. Butter
2 Tsp. Rosemary, dried
1/16 Tsp. Basil, dried
1 Tsp. Salt
¼ Tsp. Cayenne pepper
2 Cups Pecan halves
In a large saucepan, melt the butter over medium heat. Add rosemary, basil, salt and cayenne pepper; stir. Remove from heat then add the pecan halves. Toss to coat all the pecans well. Do not break the nuts. Arrange nuts in a single layer on a sheet pan. Scrape any remaining herb mixture over nuts. Bake in a pre-heated 325 degree oven for 10 to 12 minutes or until well browned. Gently stir 2 or three times during baking. Serve warm or at room temperature.
Cumin Roasted Carrots
Yields: 2 servings
30 Baby Carrots, Cleaned & Washed
½ Med. Red Onion, Shaved Thinly
10 Sprigs Cilantro
1 Tbsp. Toasted Cumin
1 Tsp. Grapefruit Zest
1 Tsp. Lime Zest
1 Cup Greek Yogurt
4 Tbsp. Pickled Red Fresno
4 Tbsp. Pickled Red Onion
4 Tbsp. Toasted Peanuts
4 Tbsp. Fried Thai Basil
In a sauté pan roast the baby carrots with oil and salt. Mix in the shaved red onions and cilantro and toss together. In a separate bowl mix together the ingredients for the sauce. Pour the Carrot mixture into the sauce bowl, mix together then scoop out onto additional plate. To finish, garnish with the toppings and serve.


text:
How gully is The Boondocks, really?
There might be a cover-up going on with regard to those supposedly censored episodes of The Boondocks, but damn it if I can't bring myself to give a shit one way or the other.
Part of the problem is that I could generally give a rat's ass about cartoons. I was a big fan of Beavis and Butthead back in the day, but that's about it. I never did get into South Park. And I've hardly ever seen anything that comes on Cartoon Network, except maybe once or twice when I was having some issues... you know, moving from the sofa and/or finding the remote.
I've been meaning to check out The Boondocks for the past couple of years though, because I know it supposedly deals with a lot of the issues that I personally find amusing. I just haven't gotten around to it. So I've yet to actually see the episodes in question, though I heard they were briefly posted to YouTube before being taken down; and my guess is that you could probably find them on some of these ghetto sites that "sample" content from YouTube and various sites from around the Internets.
Also, I've grown a bit tired of the BET-bashing in the past year so, even though I'll admit I've been guilty of it myself from time to time. Not that I hold BET in very high esteem, or that I would even know what comes on BET post, say, 1993, but I wonder if BET isn't a victim of the audience that it caters to. In other words, is the content on BET so retarded because that's the best its executives are capable of? Or is the content on BET so retarded because, come on, it's the black station. It's gonna have to be retarded, if anyone's gonna watch it.
Take for example the fact that The Boondocks itself is not on BET, but rather on the Cartoon Network, where it's probably mostly viewed by a buncha pot-smoking college-age crackety-cracks. (Though for all we know, all of these stations might be owned by the same secret cabal of tall Israelis.) This despite the fact that The Boondocks is produced by Reginald Hudlin, who's supposedly mocked rather severely in these episodes. So it's not like there would have been a problem getting a show like The Boondocks in the door over at BET. The problem is, who would have watched it?
In a story on the supposed censorship the other day at AdAge, it's mentioned that BET has been losing viewership to some of these other cable networks, which have expanded into lowbrow black reality fare - like VH1 with its Flavor Flav minstrel programs, and which ever one of these networks was running that Bobby Brown series. Which, on the one hand, would suggest that an emphasis on reality programming wasn't a very effective tack by the execs at BET; but on the other hand, it would lend credence to my theory that black folks still crave ignorance, regardless of who's serving it up.
The story at AdAge doesn't get into the continuing protests against BET and its parent company Viacom by a group of black religious freaks calling itself the Enough Is Enough campaign, but that's definitely another reason I'd have a hard time aligning myself with any anti-BET movement. While these people cry out for more diversity amongst the network's lineup of programs, it's obvious their real goal is to make the network more palatable to a relative minority of Christian supremacists. If half the time you turn on BET these days they're showing these god-awful reality shows, and the other half the time it's religious BS, I'd say they've already achieved diversity.
Of course these people seem especially incensed with the sexual content of some of the videos shown on the network, but my question to them is this: In an age when the state of romantic dysfunction in the black community may have finally thrown the entire economy - not just hip-hop - into a recession, is our main problem really the fact people do want to look at a black woman's ass? If anything we might need to see about getting BET Uncut back on the air, for the sake of the American republic. (Yep, I'm drawing a connection to the sub-prime lending crisis.)
Finally, it's been suggested that this might all be some brilliant viral marketing attempt on the part of the show's creator, Aaron McGruder. I supposed it's worked, in the sense that here I am writing about it, regardless of whether that was his intention; but I'd be wary of giving him too much credit either way, if all he's gonna do is float the idea that there may or may not have been some shenanigans going on. If he already had the sheer balls to go at his own boss like that, how come he's yet to offer a satisfying explanation as to what really went down?
My guess is that a few phone calls may have been made.


text:
Maybe Accepting Guests
- 0% response rate
- Last login over 1 year ago
Join Couchsurfing to see Jingying's full profile. It's free!
About Me
Why I'm on Couchsurfing
I like to make friends with different people
One Amazing Thing I've Done
I've climbed a mountain about 5 hours at night with my mother and we enjoyed the sunrise at the top
Teach, Learn, Share
Teach Chinses and cooking
What I Can Share with Hosts
bed, meal
Countries I've Visited
China, France
Countries I've Lived In
China, France


text:
A special thanks to Doug and Susan (and Louis, Miracle Baby) for burying St. Joseph for us in our front yard in Denver in hopes of getting a quick sale on the house.
You might not know this, but St. Joseph is the patron saint of Family, Home and Real Estate Transactions.
Our friends who like us aren't in the least bit Catholic, didn't let this little fact get in the way, and willingly drove to a Catholic store, bought St. Joseph and said a nice prayer and buried him in our front yard.
We actually got double duty done this weekend, because the one I had already ordered when Susan and Doug offered to do this, also got buried by Brian in a different spot in the yard.
So, when it's over, we'll have to dig them both up and give them a prominent spot in our new home.
Hopefully that will be soon!


text: June 10, 2015 MCC Storytelling Celebration e0822173 Community Relations, MCC - Maple Woods, Missouri Arts Council The MCC Storytelling Celebration is held in November with more than 175 performances at 120 venues in greater KC. Storytellers from all backgrounds include internationally acclaimed artists and amateur tellers. $10,586. Missouri Arts Council. July 2014 – June 2015. Proposal Report


text:
Peace Monitors Move From Indonesian Site
Published 8:00 pm, Monday, April 7, 2003
International peace monitors in Indonesia's Aceh province withdrew to the local capital Tuesday after increasing mob violence threatened their safety and imperiled a four-month-old peace deal, an official said.
"We will be temporarily relocating all of our monitors to Banda Aceh until such a time when (we are) satisfied that their security is guaranteed," said Steve Daly, a spokesman for the Henri Dunant Center, which brokered the Dec. 9 agreement.
The pact brought peace to much of the resource-rich province, but violence has increased in the past month.
Mobs, accusing the monitors of pro-rebel bias, threatened Monday to burn down an office belonging to the Swiss-based Henri Dunant Center, which has about 50 international monitors deployed across the province.
The Free Aceh Movement has fought since 1976 for an independent state. About 12,000 people have been killed in the conflict in Aceh in the past decade. The oil- and gas-rich province is located 1,200 miles northwest of Jakarta.


text:
Results 1 to 1 of 1
Salman Khan fasting for Shiv Ratri!Follow us on Social Media
Follow @iamdesirulez
Tweet #iamdesirulez
Salman Khan is back in the city from Cuba after shooting for EK Tha Tiger with Katrina Kaif. The actor had a hectic shooting schedule and before getting back to work he wants to enjoy. He is a spiritual person and believes in all religions.
As per reports, on the occasion of Shiv Ratri, which is today, Salman has organised a huge feast in his farm house. The actor will be celebrating the festival with his family and the 125 villagers staying near his farm house. Salim Khan, Salmans father reached the farm on Saturday and is doing all the preparations for Shiv Pooja. The celebration will be joined by the actors brothers Arbaaz and Sohail Khan. Also, the farmhouse has a Shiva Shrine and they have appointed a pujari to do the rituals.
Salman will be fasting for the day and the family will break it together later in the day, it as they do during the month of Ramzan. After this celebration, Salman will rest for a few more days before he starts shooting from next month onwards for Dabangg 2....being a human...


text:
OnCourse Learning forms joint venture with Madison company
OnCourse Learning Co. has formed a joint venture with a Madison company in response to a new Wisconsin requirement for certification for professional engineers who seek continuing education credits to acquire or renew their certification.
The agreement with Bjorksten/bit 7, an engineering and design consulting firm serving global clients, was announced Friday. OnCourse Learning is a Waukesha-based education and compliance solutions provider for individuals, companies, educators and government agencies.
Bjorksten/bit 7 will provide exclusive learning content aimed at improving participants' ability to manage engineering projects. OnCourse Learning will offer an online delivery structure to make the course material available at all times, according to a Bjorksten/bit 7 press release.
"Online education is mainstream and OnCourse Learning is a leading provider of professional licensing education," said Jim Frater, Bjorksten/bit 7 president. "We're working closely with OnCourse Learning to develop and offer valuable engineering and project management knowledge not typically taught in traditional engineering schools. This joint venture expands and diversifies our services beyond client engineering and design projects into direct outreach to practicing engineers throughout Wisconsin."
The venture expands OnCourse Learning's subject matter.
"In a new post-recession economy anyone seeking career advancement will need an edge," said Patrick Sheahan, OnCourse Learning president. "Not only will the (professional engineer) coursework satisfy the new state of Wisconsin requirement, but it will also provide participants with value-added knowledge of effective management and innovative design as it relates to engineering projects."


text:
I created this autumn card for my big brother, Leo. Of course this stamp of the man on the bicycle from flonzcraft.com made me think of him immediately, so I had to have it.
I set if off with this favorite tree from Penny Black and a couple of leaves from Inkadinkado. For the multicolored leaves on the tree and ground, I used a pencil eraser to make dots of green,ochre, orange and red.
I'm entering this in the Vintage Stamping Challenge http://www.flonzcraft.com/vsc/
Thanks for visiting!
Come back soon!


text:
Posts Tagged 'HIPAA'
Science Policy Around the Web – August 11, 2017
By: Saurav Seshadri, PhD
Health information privacy
Finding the legal line between voluntary disclosure and doctor-patient confidentiality
The American Civil Liberties Union (ACLU) has suffered a setback in its efforts to protect private health information from what they see as unjust and unauthorized access by the government. Last week, a court in Utah ruled that federal agents are free to collect sensitive prescription records without a warrant. The concept of 'third party doctrine', which states that individuals lose their expectation of privacy when information is disclosed voluntarily (in this case, to a physician or pharmacist), played a key role in the court's reasoning. This position contradicts common-sense expectations of doctor-patient confidentiality, as well as the spirit of the Health Information Privacy and Accountability Act of 1996 (HIPAA), which pledges that 'your health information cannot be used for purposes not directly related to your care without your permission'.
The details of the case are as follows. Like almost every state, Utah monitors the prescription and distribution of controlled substances, ostensibly to prevent drug abuse and overdose, and archives this information in a database. Utah began requiring a probable cause warrant to access the database after an incident of police misconduct in 2015, but since then, DEA agents have been circumventing this rule by using administrative subpoenas to pull any record they feel is relevant to an investigation, without judicial oversight. When Utah stopped complying on the grounds that this practice violates state law and the Fourth Amendment, the DEA challenged the state in court and won.
The decision is disappointing, considering the ACLU won a similar suit in Oregon in 2014. However, there is hope that it may be revisited soon: United States vs. Carpenter will use the context of cell phone data to question the validity of the third party doctrine, which, if successful, would have clear implications for this case. Carpenter will be argued by the ACLU before the Supreme Court this fall.
(Brett Max Kaufman, ACLU)
International science policy
Indian scientists get their day to speak out
Though hundreds of international sites participated in the March for Science earlier this year, major cities in India were conspicuous by their absence. On Wednesday, a series of public demonstrations finally gave the Indian scientific community an opportunity to add their voices to this global movement. The marches, organized by the Breakthrough Science Society, saw modest but encouraging turnout, despite reports of scientists being instructed not to attend.
India is the largest source of immigrant scientists and engineers in the US, but it lags behind its regional peers in numbers of top-tier scientific publications. Part of the reason for this discrepancy is a lack of government support for scientific institutions and funding agencies. While the Indian Department of Science and Technology has received substantial boosts in funding in recent years, budgets are still far short what scientific department heads say they need. One of the march's core demands was for the government to increase investment in R&D from ~0.8% to 3% of GDP, in line with other developed Asian countries.
The other main goal of the march was to counteract rising levels of pseudoscience and religious intolerance of science in Indian culture. Organizers point out that violent incidents motivated by superstition still occur regularly, and cite 'confrontational chauvinism' regarding science by high-ranking officials. While this toxic blend of anti-science sentiment and nationalism is not unique to India, the country is unusual in that its constitution explicitly includes developing a scientific temperament as a 'Fundamental Duty' of its citizens. Ultimately, as in the US, the extent to which such events will truly promote rational discourse and evidence-based policy remains to be seen.
(Sanjay Kumar, Science)
Marijuana legalization/Opioid crisis
Hands-off/Hands-on approaches to the war on drugs
Initial recommendations from two separate commissions on drug policy set up by the Trump administration have yielded unexpected results. First, the Task Force on Crime Reduction and Public Safety has urged officials to continue the Obama administration's hands-off stance on enforcing federal anti-marijuana laws. This is a surprising outcome, considering the Task Force was created by Attorney General Jeff Sessions, and was expected to support a crackdown on state-level legalization: Sessions has blamed marijuana for increased violent crime, and recently notified several pot-tolerant states that they will face increased scrutiny from his Justice Department. Though the report's suggestions are not binding and several methods to discourage legalization still exist (such as raiding dispensaries or suing state governments), given the overwhelming public support for legal marijuana and Sessions' increasingly tenuous political position, it appears unlikely that any significant changes in enforcement policy are on the way.
The second report comes from the President's Commission on Combating Drug Addiction and the Opioid Crisis. The death toll and burden to society of opioid addiction have increased dramatically in recent years, and the commission offers several constructive, bipartisan solutions that echo those advocated by public health and drug policy experts. However, Trump has already signaled his disinterest in these suggestions, ignoring the commission's 'urgent' request to 'declare a national emergency under either the Public Health Service Act or the Stafford Act' in order to divert more resources into fighting opioid abuse. Trump routinely exploited the opioid epidemic for political points while on the campaign trail, often using it to justify 'tough-on-crime' proposals such as a Mexican border wall, mandatory minimum sentencing, and property seizure. The report does not recommend any of these measures, instead encouraging expanded drug treatment under Medicaid, which would have been gutted by the GOP's attempted repeal of the Affordable Care Act. Failure to effect change in opioid-afflicted communities, which strongly supported Trump in 2016, could be politically costly for him in 2020; but steadily climbing rates of addiction mean that this timeline would be too late for many.
(Daniel Politi, Slate, and Christopher Ingraham, The Washington Post)
Have an interesting science policy link? Share it in the comments!
The Debut of Health Care Data Science
By: Fabrício Kury, M.D.
It is easy for a millennial – a person born between mid-1980's to late-90's – to be unaware of just how young the current methods used in health care research really are. Controlled randomized clinical trials (RCT), dating only from the late 40's, are probably younger than most millennial's grandparents. Case-control methodology and Kaplan-Meier curves only originated in the 1950's, while meta-analyses were only accepted by medical researchers in the late 70's. Step into the 80's and early millennials are as old, if not older, than propensity scores and the concept that is today called cost-effectiveness research. The term "Evidence-Based Medicine" is as young as a millennial born in the early 90's, while the late 90's and 2000's saw the explosion of genomics, proteomics, metabolomics, and other -omics research. Finally, the 2010s so far might be credited for when the term Data Science ("the fourth paradigm of science") gained widespread notoriety, and established its modern meaning as – long story made short – the practice of producing knowledge out of data that had been created for other purposes.
While the second half of the 20th century transformed health care research into an ever more rigorous and technology-driven science, it also saw the cost of the health care sector of the U.S. unrelentingly grow from a comfortable 5% of the Gross Domestic Product in 1960 to a crushing 18% in 2015. Medical bills have become the leading cause of personal bankruptcies in the nation, while life expectancy, as well as other basic health indicators, depicted a country nowhere close to getting a similar bang for each buck as other developed nations. In 2009, the Obama administration prescribed to the health care sector a remedy that had previously brought efficiency and cost savings to every industry it had previously touched: information technology. The Health Information Technology for Economic and Clinical Health (HITECH) Act (part of the American Recovery and Reinvestment Act of 2009) literally gave away as much as $36.5 billion of taxpayers' money to hospitals and physician practices for them to buy and "meaningfully use" electronic health records (EHRs). This outpouring of money was overseen by the Office of the National Coordinator of Health Information Technology (ONC), which had existed since 2004 as a presidential Executive Order, but became solidified as a legislative mandate via HITECH. This act fiercely transitioned the country from mostly paper-based health care in 2008 to near-universal EHRs adoption by 2015, giving electronic life, and potential reuse for research, to streams of health data previously dormant in paper troves.
Moreover, in March, 2010, the Patient Protection and Affordable Care Act (PPACA, a.k.a. "Obamacare") was signed into law and, among so many other interventions, secured a few hundred million dollars for the creation of the Patient-Centered Outcomes Research Institute (PCORI). The mission of the PCORI is to do research that responds directly to real-life concerns of patients. For that purpose, among the first initiatives by the PCORI was the creation of PCORnet, a network of institutions capable of providing electronic health data for research. Most recently, in January 2015, President Obama announced the Precision Medicine Initiative (PMI). The PMI seeks to craft a nationwide and representative cohort of 1 million individuals, from whom a wealth of health data will be collected with no definitive goal besides to serve as a multi-purpose prime-quality dataset for observational electronic research. Meanwhile, private sector-led initiatives such as Informatics for Integrating Biology and the Bedside (i2b2) and Observational Health Data Sciences and Informatics (OHDSI) were also launched with the mission to access and do research on health care's big data, and their publications can be easily found in PubMed.
These initiatives depict a political and societal hope – or hype? – that information technology, among its other roles in health care as whole, can make health care research faster, broader, more transparent, more reproducible, and perhaps also closer to the everyday lives of people. One premise is that by using existing EHRs for research, instead of data collected on-demand for a particular study, the researcher gets closer to the "real world" individuals that ultimately receive the treatments and conclusions produced by the study. In traditional clinical trials and other studies, the patients who participate are highly selected and oftentimes remarkably unrepresentative of the general population. Moreover, in EHR-based research there is also the potential to investigate more individuals than any previous method could possibly attempt. This broader reach makes rare conditions (or combinations of conditions) not so rare that they cannot be readily studied, and allows subtler variations in diseases to become detectable. On top of that, these studies can be done at the speed of thought. De facto, electronic health records-based clinical research has been recently published in the Proceedings of the National Academy of Sciences (PNAS) and evinced to be feasible at international, multi-hundred million patients scale at a breathtakingly swift time span. Altogether, one can sense in this picture that the millions of dollars spent on HITECH, PCORnet, PMI, and the NIH's Data Science research grants might not have been just unfounded hype.
The relationship of IT and health care must, however, recognize its rather long history of frustrated expectations. In 1968, for example, Dr. Laurence Weed – the father of today's prevailing paradigm of patient notes – predicted that in the future all text narratives present in electronic health records would be entered in structured form that enables scientific analysis. Today, to say the minimum, we have become less confident about whether such change is feasible or even desirable to begin with. In 1987, Barnett and colleagues believed that "relatively simple computational models" could be used to construct "an effective [diagnostic] assistant to the physician in daily practice" and distributed nationwide, but such assistant is yet to arrive at your physician's office downtown (although, truth be recognized, it might be around the corner). While presently teaming with excitement and blessed with incentives, the journey of IT into health care and health care research is invariably one of uncertainties and risks. Health information technology has been accused of provoking life-threatening medical errors, as well as – like previous technological breakthroughs along the history of Medicine, including the stethoscope – harming the patient-physician relationship and the quality of care. The editors of the New England Journal of Medicine early this year went as far as to state that data scientists are regarded by some clinical researchers as "research parasites."
Moreover, the Federal Bureau of Intelligence has investigated that medical information can be sold on the black market for 10 times more than a credit card number, while at the same time cybersecurity experts are stunned by the extreme vulnerability of current U.S. health care facilities. This provides sensible ground for concern about patient privacy violation and identity theft once the health records have moved from papers into computers. Unlike a credit card, your medical and identity information cannot be cancelled over the phone and replaced by a new one. Patient matching, i.e. techniques for recognizing that data produced at separate sites refer to the same person, oftentimes confronts blunt opposition by civil opinion, while the ultimate ideal of a National Patient Identifier in the U.S. is explicitly prohibited by present legislation (HIPAA). Such seamless flow of interoperable health data between providers, however, is the very first recommendation expressed in 2012 by the Institute of Medicine for realizing the Learning Health Care System – one that revolves around the patient and where scientific discovery is a natural outgrowth of patient care.
With or without attaining the ideal of a Learning Health Care System, the U.S. health care system will undergo transformation sooner or later, by intervention or by itself, because the percentage of the GDP that is spent on health care can only continuously increase for so long. Information technology is at minimum a sensible "bet" for improving efficiency – however, the power of IT for improving efficiency lies not in greasing the wheels of existing paradigms, but in outclassing them with novel ones. This might be part of the explanation for the resistance against IT, although there does exist some evidence showing that IT can sometimes do more harm than good in health care, and here the word "harm" sometimes can mean patient harm. The cold truth is that, in spite of decades of scientific interest in using computers for health care, only very recently the health care industry became computerized, so we remain not far from the infancy of health care informatics. Nevertheless, Clinical Informatics has been unanimously approved in 2011 as a board-certified physician subspecialty by the American Board of Medical Specialties, signaling that the medical community sees in IT a permanent and complex duty for health care. Similarly, the NIH has in late 2013 appointed its first Associate Director for Data Science, also signaling that this novel field holds importance for health care research. Finally, there might be little that can be done with the entire -omics enterprise, with its thousands over thousands of measurements multiplied by millions of patients, that does not require data-scientific techniques.
The first cars were slower than horses, and today's high-speed, road-only automobiles only became feasible after the country was dependably covered with a network of roads and freeways. Such a network was built not by the automobile producers, but by the government upon recognition that it would constitute a public good. The same principle could very well be the case of health care IT's important issues with privacy, security and interoperability, with the added complication that it is easy for an EHR producer to design a solution but then block its users from having their system interact with software from competing companies. Now that health care records are electronic, we need the government to step in once again and build or coordinate the dependable freeways of health care data and IT standards, which will also constitute a public good and unlock fundamental potentials of the technology. Health care, on top of its humanitarian dimension, is fundamentally intensive in data and information, so it is reasonable to conjecture that information technology can be important, even revolutionizing, for health care. It took one hundred years for Einstein's gravitational waves to evolve from a conjecture based on theoretical fundaments to a fact demonstrated by experiments. Perhaps in the future – let us hope not a century from today! – some of the data-scientific methods such as Artificial Neural Networks, Support Vector Machines, Naïve Bayes classifiers, Decision Trees, among others, in the hands of the millennials will withstand the trial of time and earn an entry at the standard jargon of medical research. Just like how, in their generations, meta-analyses, case-control studies, Kaplan-Meier curves, propensity scores, and the big grandpa of controlled randomized trial were similarly accepted.


text:
Question about Lexmark Platinum Pro905 multifunction InkJet Printer
Print out comes with unwanted black squares printed at random.
Posted by Anonymous on
SOURCE: I have freestanding Series 8 dishwasher. Lately during the filling cycle water hammer is occurring. How can this be resolved
A 6ya expert can help you resolve that issue over the phone in a minute or two.
Best thing about this new service is that you are never placed on hold and get to talk to real repairmen in the US.
The service is completely free and covers almost anything you can think of (from cars to computers, handyman, and even drones).
click here to download the app (for users in the US for now) and get all the help you need.
Good luck!
Posted on Jan 02, 2017
SOURCE: Unwanted Yellow Highlighting
For the internet problem, try using the Lexmark Toolbar.
Posted on Aug 07, 2008
SOURCE: I have a Lexmark E232 laser printer. I have just
All laserjet printers and laserject function on the same basic principles and unwanted marks, streaks, line etc, which are repeated in a pattern are mostly due to the deterioration of the cartridge parts(photoconductor and PCR roller mainly). The problem can be fixed by correctly identifying the faulty part and replacing it. This saves the cost of buying a new toner. However, sometimes cleaning the visible inside of the printer and cartridge roller greatly helps, which can be easily done using dry lint-free cloth and gently cleaning the photoconductor etc. Good Luck!
Hope it Helps!
Posted on Nov 26, 2010
Tips for a great answer:
Jan 18, 2011 | Canon PIXMA iP4200 InkJet Photo Printer
Dec 29, 2010 | Office Equipment & Supplies
Dec 13, 2010 | HP OfficeJet V40 All-In-One InkJet Printer
Jul 12, 2010 | Ricoh Aficio AP3800C Laser Printer
Apr 19, 2010 | HP LaserJet 2550n Printer
Dec 19, 2009 | Brother MFC-7220 All-In-One Laser Printer
Jun 09, 2009 | Epson STYLUS R230 InkJet Photo Printer
Apr 28, 2009 | HP Officejet 5610 All-In-One InkJet...
Sep 29, 2008 | Brother MFC-7820N Laser Printer
Nov 01, 2007 | Lexmark P6250 All-In-One InkJet Photo...
Mar 27, 2014 | Lexmark Platinum Pro905 multifunction...
See all Lexmark Platinum Pro905 multifunction InkJet Questions
14 people viewed this question
Usually answered in minutes!
Level 3 Expert
1018 Answers
Level 3 Expert
18424 Answers
Level 3 Expert
7733 Answers
Step 2: Please assign your manual to a product:


text:
What happens when you do a System Restore on a computer?
System Restore is a management tool in Windows that allows you to restore your computer to a previous state or restore point when it was functioning correctly. Windows basically takes a picture of...
Read More »
How do I system restore my computer?
You need to boot into Windows Recovery Environment Turn the computer on, and immediately press and hold the F8 key.After several seconds, the Advanced Boot Options screen will appear.Use the up and...
Read More »
How do I restore a system on a computer?
Locate System RestoreClick on the "Start" button located in the bottom-left corner of your desktop screen. Select "All Programs", click "Accessories" and choose "System Tools." Select the "System R...
Read More »
How to Restore a Mac Computer System?
Restoring a damaged or malfunctioning computer system is the last step a user can take to reclaim his computer from a malicious virus infection or severe system error. To make the restoration proce...
Read More »
My Computer Won't Do a System Restore?
Several things keep computers from completing a system restore, but conflicts in the main drive of the computer are usually the cause. Installation of new software can also cause conflicts in a co...
Read More »


text:
::vegetarian diet
was shopping around at 'Luo Si Wan', a wholesale market at Kunming, Yunnan, for project stuff and saw this cute doggy.. ha, how could i resist? so i stooped down in the middle of the streets and snapped happily away, creating quite a commotion.. i think it is these details that makes this trip so unforgettable..
i have always contemplated the omniverous diet of humans. it is true that in some parts of the world, meat is vital to provide the necessary fats and hide to withstand the harsh winters. however, in many others, meat is a luxury item, relished for its ability to satiate our taste buds and fulfill our craving for juicy, rich aromas..
however, there seems to be a strange preference of certain meats over others. for example of pork over frog meat, veal over dog meat, chicken meat over chicks' meat.. in our 'civilised' world, animals we can relate to, those cuddly ones, or those we abhore, like those slimy ones, are not to be eaten. of course this doesn't apply to everyone as we all know how some tribes in Africa relish fried caterpillars and how our Thai friends queue up for some juicy fried tarantulas. The point is we eat animals because we are desensitised, we don't feel for them anymore. and we don't eat those we feel for, be it those we like or those we don't.
then this question come to my mind. who gave us to power to decide whether we should have fish or beef for dinner tonight. or more aptly, who gave us the power to decide which one to be killed for consumption. is it because we are more intelligent, and thus have the ability to capture, breed and kill?
it is true that when we eat meat, we did not specifically order for them to be killed; unless of cos you are in a seafood restaurant and pointed to a fat sea bass to be steamed. nonetheless, the meat was from another sentient being. we do not know for sure how long their memory is, or whether they even feel emotion or not. but for sure, from they way they struggle, we know they can feel pain.
i am an omnivore too, and i do eat meat. to convince one to turn to a vegetarian diet requires considerable effort, for both parties. i am not a vegetarian myself, and i don't think i will be one in the near future. however, i have decided to cut down my consumption of meat and eat them only when my family is or i am sharing with my friends. to do otherwise would be imposing a strain on others. things do not change overnight, but i do hope that one day, the number of chickens, pigs, cows and fishes killed would drop. but even for now, whenever we eat meat, we can silently thank the animal for nourishing our body, for sacrificing their lives to satisfy us.
i believe if we use a compassionate heart that reaches out to not just other humans but animals and other sentient beings as well, we can improve the society and spread the idea of peace. it is actually quite simple, when we look at meat, we can picture the animal and naturally, our ability to empathise would flow and we can literally feel their pain.
thanks for reading through this whole chunk if you have. ;p i would like to end off with a quote from Albert Einstein:
"Nothing will benefit human health and increase the chances of survival of life on earth as much as the evolution to a vegetarian diet."
i was equally surprised to hear that from him too.. and don't you think the doggy above is cute?
+ |-jX-| updated @ 1/28/2007 10:56:00 PM | past comments | | | permalink| add as fav
[to view previous days' photo, select the next link under pReVioUsLy to the right. or you can view my aRcHiVe.]
Check out my portfolio. For photography services or assignments, contact me at firstname.lastname@example.com
on the edge
droplets sparkle


text:
SUNY Buffalo biochemistry degree
To request course information, please complete this form. You may receive information from just one program, or several. Before making decisions about your future, compare programs carefully.
Think about what career is best suited for you, and where you want to study. Request more information now.
Think about what career is best suited for you, and where you want to study. Request more information now.
To request course information, please complete this form. Before making decisions about your future, compare programs carefully.
Think about what career is best suited for you, and where you want to study. Request more information now.
Think about what career is best suited for you, and where you want to study. Request more information now.
To request course information, please complete this form.
Think about what career is best suited for you, and where you want to study. Request more information now.
Think about what career is best suited for you, and where you want to study. Request more information now.
Get info about SUNY Buffalo biochemistry degree, registering for degree programs, and taking tests for free online. Given the breadth of engineering specializations, you may find your niche within the engineering field. Technical training is only the first step towards a rewarding career. If you earn a biochemistry degree, for example, there are a variety of concentrations within engineering that may appeal to you such as biotechnology, chemical engineering, or petroleum exploration. Further, due to advances in technology, there is a growing shortage of biochemistry degree graduates. Please use the form above to request admissions info for SUNY Buffalo.
Chemical engineers apply the principles of chemistry and biology to solve problems in the production of chemicals, fuel, pharmaceuticals, and many other products. They design processes and equipment for large-scale manufacturing, plan and test production methods and byproducts treatment, and direct facility operations. Most chemical engineers have a biochemistry degree, as well as internship experience. They may spend a large portion of their work day at industrial plants, refineries, and other locations, where they monitor or direct operations or solve onsite problems. The average salary for chemical engineers was $97,360 as reported the US Bureau of Labor Statistics in May 2015.
Biomedical engineers design equipment, devices, computer systems, and software used in healthcare. Biochemistry degree programs may include extensive lab-work, and courses such as fluid mechanics, computer programming, circuit design, and biomaterials. Accredited programs also include substantial training in engineering design, and practical internships in medical device and pharmaceutical manufacturing companies. The median annual wage for biomedical engineers was $86,220 in May 2015. Further, employment of biomedical engineers is projected to grow 23% in the next decade, which is much faster than the average for all occupations.
Systems Engineer
Terran Orbital
Work closely with electrical, mechanical, software, and operations engineers to develop optimal solutions to complex problems.
5 days ago Senior Engineer, Electrical Manufacturing - Critical Care
Edwards Lifesciences
Electrical Manufacturing Engineer is an exciting opportunity to collaborate on projects and initiatives in support of Edwards Lifesciences Advanced Hemodynamic..
3 days ago Solar Project Engineer - Phoenix, AZ
US Professional Services
Solar, project engineer, revit. Solar Project Engineer - Phoenix, AZ. 10-12 month contract.
5 days ago Power Plant Technician A
Veolia Environnement
Operate, monitor and respond to normal and abnormal operating conditions of power plant equipment and auxiliaries Takes readings and maintains records..
4 days ago Energy Engineer
Futures Consulting
The Energy Engineer will be expected to participate in industry conferences, obtain relevant industry certifications and to meet project deadlines..
4 days ago Electrical Engineer Graduate
Huitt Zollars
Degree in Electrical or Architectural engineering. Huitt-Zollars' Fort Worth office has an immediate opportunity for an entry-level Electrical Engineer Graduate..
4 days ago
Environmental Engineering
Environmental engineers may be called upon to design municipal water supply systems, and industrial wastewater treatment methods. They must evaluate the watershed, and balance the demand against available reserves. In the case of drinking water, treatment focuses on minimizing the risk of infectious diseases, and ensuring adequate distribution. In the field of air pollution management, environmental engineers devise ways to minimize emissions from vehicle exhausts and industrial gas stacks. To some extent, this field overlaps the attempt to decrease carbon dioxide levels, in order to combat global warming. The US Environmental Protection Agency (EPA) is one of the principal agencies that work with environmental engineers to protect and improve air, water, and overall environmental quality. Environmental engineering technicians holding an associates degree may earn $48,650 per year, while environmental engineers who have a bachelor's degree can earn as much as $79,500 annually.
Online Tests - Free Practice!This section offers practice tests in a variety of subject areas. Each of the following multiple-choice tests has 10 questions to work on. No sign-up is required, just straight to the test.
Other colleges near Buffalo, New York:Take a few moments to browse other colleges and universities near Buffalo. It's a good idea to compare all schools in your target area, as well as consider taking some of your classes online. By continuing your education, you can improve your salary prospects or train for a more interesting position. Financial aid deadlines are typically set well in advance of regular admission dates, so be sure to apply early. You may request free information from several different schools below, without making a commitment.
Engineering Job ListingsThe Fundamentals of Engineering exam should be taken immediately after earning a bachelors degree from an ABET-accredited program. Engineers who pass this exam are called engineers in training (EIT), or engineer interns. After meeting work experience requirements, engineer interns can attempt a second certifying exam, called the Principles and Practice of Engineering Exam. Thereafter, acquisition of a professional engineering license enables management of junior engineers, the ability to sign off on engineering projects, and provide services directly to the public. Wages vary by employer and location. Aside from salary, most engineering jobs include excellent benefits, as well as retirement plans.
|Job listings below are updated hourly:
|Starting Salary
(up to)
|10 Year Salary
(up to)
|Aerospace Engineers
|Aircraft Mechanics
|Android Apps
|Civil Engineers
|Electrical Engineers
|Environmental Engineers
|Graphic Design
|Industrial Engineering
|Maintenance Technician
|Mechanical Engineers
|.NET Developer
|Network Analysts
|Solar Energy
|Software Development
|SWIFT, iOS
|Technical Writers
|Urban Planners
SUNY Buffalo biochemistry degreeApply to several colleges and universities simultaneously, and if you have the grades and test scores, give yourself a fighting chance to get into a top-rated program by doing something outstanding in high school or community college. It isn't as hard as you might think to get an article written in your local newspaper. An advanced degree will stick with you for a long time, so apply yourself and work hard for a few years, graduating from the best school that you can get into.
SUNY Buffalo biochemistry degree
1300 Elmwood Ave
Buffalo, NY 14222
1300 Elmwood Ave
Buffalo, NY 14222


text:
It's going to get a whole lot bigger too, he hopes, if the initial public offer of Glencore is a success. Having pledged not to sell any of his 15.8pc stake in the mining and commodity trading company, he has little interest in making the share offer anything other than a happy experience for himself and his fellow investors.
This is the brutal, rather unscientific but nonetheless honest appraisal of why this IPO stands a pretty good chance of being a success.
Glasenberg knows that if his beloved Glencore's wealth-creating potential is to be fully realised it has to shed its private partnership status and adopt that of a public company. Glencore needs access to capital so it can continue growing, and it needs liquidity in its shares for the benefit of both new and existing shareholders.
So investors, such as Glasenberg, will want to see the bulk of the $10bn of fresh equity being raised in Glencore's IPO put to work profitably. They will want to see the company's resulting dividend grow too, 15.8pc of which goes to Glasenberg every year.
That's why the 480p to 580p price range, giving a £36.5bn mid-range market value, is dear but not greedy. Glencore has received pledges from a cadre of lead investors, including BlackRock and Fidelity, not to mention various private banks, hedge funds and sovereign wealth funds, to buy up to 31pc of the new shares on offer at the top end of the price range.
While they are willing to pay that price, I doubt many are expecting to pay that price even if the offer is heavily oversubscribed. Their presence, as so-called cornerstone investors, is to provide a vote of confidence in a company that until now has been shrouded in secrecy and has already shown an unsure touch when it comes to crucial areas such as corporate governance.
Its new chairman, Simon Murray, has already made himself unpopular with sexist remarks in an interview with The Sunday Telegraph.
While these investors are not beyond making a duff call, neither are they complete fools. They believe a price within the range quoted is an acceptable valuation compared with other quoted mining companies. Even at 580p, they believe the company will deliver the necessary increase in earnings this year to justify such a price. With so many investment banks involved in the float there are precious few independent analysts out there, so this up-front expression of buy-side confidence is a useful guide.
That said, it is going to take the market some time to understand Glencore. Roughly a third of its value is wrapped up in its trading business, which essentially markets the natural resources the rest of Glencore's operations dig out of the ground. A third of the group's value can be attributed to its own physical assets, such as Cobar, its 100pc-owned copper miner in Australia.
But another third is invested in the shares of other mining companies, such as Russia's Rusal. In the eyes of many investors, this will give Glencore the feel of an investment trust and therefore deserving of a discount to its net asset value. Glasenberg, however, is determined to prove all the group's capital is being put to work for a reason, so it's unlikely any discount will be as wide as those that dog traditional investment trusts (a handful of which trade at a premium).
Life is now changing fast for Glasenberg and his team, who are subject to lock-ups to stop them selling shares in the short term. Maintaining the culture of success at Glencore could be one of the biggest challenges the company faces as it moves into the public arena, but the lessons of previous partnerships that floated, such as Goldman Sachs, suggests it can be done.
How Xstrata fits into the decision to float
There remains another reason for Glasenberg's decision to float Glencore. And that's to create a currency to help pay for a deal with Xstrata, the $71bn mining company in which it already owns a 34pc stake.
There was the possibility of combining with Xstrata before an IPO, but Xstrata's shareholders gave that the cold shoulder during informal consultations.
No deal that a private Glencore was happy with would make Xstrata shareholders happy. It would be impossible to properly establish the value of what was being proposed. So floating allows Glasenberg to pursue Xstrata with a reasonable chance of success, but will ensure he has to pay top dollar.
Any deal will have to be couched as a takeover bid for Xstrata with a premium paid for control. Xstrata has already altered the make-up of its board to prepare it for the fight over value, but its shares could be as profitable a buy in the short term as Glencore's new equity.


text:
Students examine the relationship between 'Abdu'l-Baha and Baha'u'llah and see 'Abdu'l-Baha as the Exemplar of spiritual qualities. They discuss the qualities that made this man special and share examples of times when they have done something nice for someone else.
3 Views 0 Downloads
Resource Details
Start Your Free Trial
Save time and discover engaging curriculum for your classroom. Reviewed and rated by trusted, credentialed teachers.Try It Free


text: A 14-YEAR-OLD boy died after being knocked off his bike by a driver who then sped off. Medics fought to save Sitting-bourne Community College pupil Kyle Coen after the incident at 9.15pm on Monday. But their efforts were in vain and the popular teenager was pronounced dead at the scene, outside Bapchild Cricket Club. A grey Fiat Bravo, believed to have been the car involved, was later recovered nearby by police. As the Sittingbourne News Extra went to press, a 27-year-old woman and a man of 23 were helping detectives with their inquiries. It is believed Kyle was cycling to see his girlfriend in Teynham at the time. Speaking at the scene yesterday, Linda Stock, whose son Alex, 14, was Kyle's best friend, said: "He was a very gentle, good lad, never been in any trouble. I feel so much for his family. My heart and prayers go out to them. It's such a tragedy."


text:
Instant Gratification with Hair Extensions
Ever wondered how your favorite celebrity switches between a variety of hairstyles in just a few days (sometimes hours)? There's a growing hair trend among the celebrity set that is making it easier than ever to experiment with new styles in an instant: hair extensions! If concerns about quality, usage, appearance, or maintenance have stopped you from testing these new waters, fear not. Below we've outlined some frequently asked questions that take the guesswork out of this growing trend.
Why Extensions?
Hair extensions offer versatility and protection. They are a quick, simple way to add length, color, or volume without the commitment. Making changes to your real hair can run the risk of causing permanent damage or resulting in a style that you may not be in love with. Think of extensions as a trial run before the full undertaking.
Who Uses Them?
Anyone and everyone! Extensions come in a variety of colors, textures, and lengths. Examples of styles that can be created with these add in pieces include extravagant updos, intricate french braids, beautiful curls, or pin straight locks reminiscent of Cher's iconic 70s style. If you need further evidence of how versatile (and ubiquitous) extensions can be, take inspiration from celebrities including Solange Knowles, Kelly Ripa, and Gwen Stefani.
What Options Are Available?
We offer a variety of hair extensions that provide a natural appearance and meet your specific needs. There are full-piece extensions that run the length of the entire head, sectioned pieces that can be used to fill in thinning/problem areas, or pieces created specifically for the hairline, or clip-in extensions for that anytime wear. Extensions come in four lengths with colors ranging from black to platinum blonde; there are even "Fantasy" varieties that are pre-colored in on trend pastels and other non-traditional hair colors!
What Are They Made Of and How Are They Applied?
Salon Daniel uses Hot Head and BABE extensions. These revolutionary brands are created from human remy hair and come in multiple pieces. Remy hair is the highest quality human hair and describes extensions that have kept the hair cuticle intact. This is important because it allows the hair extensions to remain undetectable when applied to the hair. Unlike most extensions currently on the market, these adhesive pieces are applied without the need for heat (which protects your natural hair!). We also offer a variety of other techniques for applying extensions, such as beads, keratin fusion, tape-in, and clip-ins.
How Are They Maintained?
Because these extensions are created from human hair, they can be treated in the same manner as your own hair. Wash, condition, and apply heat as you normally would (still exercising the same TLC you would provide your own locks). Water activates a body wave in the extensions, offering another style alternative. Due to its high quality, our extensions can be reapplied up to three times and last between eight and 10 weeks.
Pricing varies on the length and type of hair. Schedule a consultation now!!
3 Replies to "Instant Gratification with Hair Extensions"
Non Surgical Hair Care Treatment Services in Hyderabad
May 27, 2016 (9:39 am)
Well good article to all thanks for sharing this post its interesting one, Have a look to Style Mollah blog, In this blog can get best ways top get hair transplantation and replacement are there sure it will use
Non Surgical Hair Care Treatment Services in Hyderabad
June 16, 2016 (10:06 am)
Good article, it's very helpful to all. I am very impressed about that you mentioned in this article, thanks for sharing this post. I got best useful information from your site's blog.
Hair Extensions 101 - Pool Aviation
June 11, 2017 (3:22 pm)
[…] Hair extensions comes in a variety of intricate colours […]


text:
this doctor is not a good person as he teases different parts of her mature body to satisfy his fetish of playing with the body of mature women. he is also hoping that it is going to turn on the granny enough to have her interested in having sex with him.
- lolamed
- : 4min 57sec
- : 29 Dec 2011
- Exclusive video
- : Vera


text:
my dad got samil this zebra tent on HIS first resort trip and it's great. it's a little bigger than a beach tent, but i prefer it. it's got windows all around and is big enough for two kids - without the bigger kid bothering the little kid.
amely spent most of her time sleeping in the zebra.
and yes, she IS wearing a bathing suit. she has 5.
perhaps. but samil has 9.
c'mon people, we live an hour from the ocean.


text:
There's a heated discussion going on in social media within Tanzania about upcoming elections - but you'd never know it. It happens in closed groups like WhatsApp. DW takes a peek at what they're talking about.
Messenger apps have now moved well beyond exchanging texts and images. Soon, users will be able to shop, pay bills and transfer money through WhatsApp, WeChat and Line. (20.10.2015)
Tanzanians are set to go to the polls in one of the most tightly contested elections since independence. The youth vote could determine the outcome; young Tanzanians want a government that addresses their concerns. (20.10.2015)
His incendiary comments are the stuff of brand-new hashtags, his behavior is rich fodder for online memes. Republican presidential candidate Donald Trump has mastered the art of leading social media polls. Here's how. (27.08.2015)