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All Forums Other Banjo-Related Topics Collector's Corner ARCHIVED TOPIC: Arthur E. Smith
Please note this is an archived topic, so it is locked and unable to be replied to. You may, however, start a new topic and refer to this topic with a link.
mike hansen - Posted - 04/14/2007: 20:30:13
Can anyone here tell me anything about Arthur E. Smith banjos:I have a new Banjo student...she came in with the normal "too big" soft case and I expected the usual lot...a cheep-o...but lo & behold...out comes an Arthur E Smith open back.It does not look to be a really expensive model, but It's coolRosewood fretboard...maple neck and pot..really top quality hardware...single coordinator rod...I helped her set it up and it sounds great..it was her grandfather's but she is hoping he will give it to her because he never learned to play it...What's the value of these...what's the story: Who was arthur e smith, where is he from, etc....thanks in advance...,Mike in Baltimorewww.myspace.com/ricehouserecordsBart Reiter "GALAX" Model (calf skin head)
Edited by - mike hansen on 04/14/2007 20:31:09
ballbanjos - Posted - 04/14/2007: 21:01:08
The AES banjos were some of the best of the 70's. I especially liked the internal resonator models, but even the simple ones were really nice--about as good as it got in the mid 70's.Kate Spencer of Maple Leaf Music in Vermont was responsible for the Smith banjos. Great instruments!Dave
Stevec - Posted - 04/14/2007: 21:05:23
I'm not sure of the exact dates, but Arthur E. Smith banjos were being built in the late 70's and early 1980's, I'm not positve, but I think Arthur E. Smith was a name for the company rather than the maker. Kate Spencer of Maple Leaf Music in Brattleboro, VT - http://www.mapleleafmusic.com - was one of the former owners of the company. You could contact her for more info. I had a friend who a a Maple Leaf model back in the early 80's, it was a nice solid banjo.That your student has her grandfathers makes me feel a little old, but I suppose that if I hadn't been more careful back in the 70's and 80's I could be a grandpa too.Steve
oldwoodchuckb - Posted - 04/15/2007: 03:55:27
The makers used to come to the Fox Hollow festival in the late 1970s. I'm not sure when they started or quit but they were about the best non-custom (semi factory? whatever one wants to call it) openbacks of the era --- and the banjos were GOOD. Good value, good quality, good work all around. I was into "vintage" instruments at the time but I seriously considered buying one. I think the banjos they were making might have had some influence on my eventually going to "modern" banjos -- and of course, now those Arthur E. Smiths ARE vintage. What goes around, really actually goes around.The Whiskey Before Breakfast variations and a few tunes in "F" tuning are now available on the web at:http://home.thegrid.net/~fjbrad/id20.html
timmo_1949 - Posted - 04/15/2007: 12:57:48
It is my understanding that Arthur E. Smith was a popular Country singer & musician in the 1960s and perhaps later. He decided, near the peak of his fame, to market a line of instruments, including banjos and (I believe) guitars. I have seen two of the banjos. One was a near-the-bottom-of-the-line job but still a pretty nice banjo. I thought it was a little more flash than substance, i.e., it could have been built a little more carefully. Just a few days ago, I ran across another AES banjo, this one a top-of-the-line item. Very pretty, very nice workmanship.They appear to be rare. In watching eBay carefully for 5 years now, I have never seen one there.Timmohttp://savethebanjos.com"Bother Yum-Yum!"
Stevec - Posted - 04/15/2007: 14:47:24
I think that's a different Arthur Smith. Arthur "Guitar Boogie" Smith the country star you refer to was not involved in the A.E. Smith banjo company. He and Don Reno wrote "Fuedin Banjos" which was used without credit to Smith in the film "Deliverance" and called "Dueling Banjos". Smith sued and won back royalties. He used the "Guitar Boogie" moniker to avoid confusion with another famous Arthur Smith, the fiddler who played with both the Delmore and McGee Brothers.According to Mugwumps Vol.3 #5 the A.E. Smith banjo company was founded in 1973 in Massachusetts. Micheal Holmes includes a post script after a short highly positive write- up on the banjo company "Unless you have 20 minutes to spare, don't ask who Arthur E. Smith was!"Steve
Edited by - Stevec on 04/15/2007 15:55:25
ndlxs - Posted - 04/15/2007: 15:09:06
The brass tone ring, non-internal resonator model was called the Northampton; I had one that I bought in 1978. In 1981, some fortuitous accidents on the part of others allowed me to buy a Shelburne II, the internal resonator model, which is still my main banjo. Great, sweet, banjo, all I have ever done with it is had the neck reset once, and refretted once. Grab 'em if you see them. All of the songs on my homepage here were done on my shelburne.Andy AlexisSacramento, California "The Pearl of the Central Valley" Buy my CDs:http://cdbaby.com/cd/pineycreekand http://www.offtocalifornia.com
Bill Rogers - Posted - 04/15/2007: 15:09:16
Classic record label: "Arthur 'Guitar Boogie' Smith plays Guitar Boogie by Arthur Smith"Bill
DJMorgan - Posted - 04/15/2007: 15:27:21
They were made in Greenfield, MA. Hence their models were named after surrounding towns, Northampton, Shelburne.Nice banjos. I've been looking for one for some time.
Edited by - DJMorgan on 04/15/2007 15:28:09
silvioferretti - Posted - 04/15/2007: 17:51:53
I bought an A.E. Smith Northampton model in 1978, my first "real" banjo, and it was very nice, maple, ebony fingerboard, loud and punchy for a "basic" banjo. I had to sell it in my times of need, and still regret it. Then I found another one for sale about a year ago here on the HO, and didn't miss the opportunity. A Northampton again, this time cherry with a rosewood board, sounds a little softer but IMO better than the first one. I just recorded a tune for our new CD on it yesterday, and it miked great and sounds great. I love it.Kate Spencer was a great help in letting me have my first AES banjo and learn how to set it up and so on, I think she's a great lady and a fine builder. AES was just her and her partner Mark Surgies, so AES banjos ar by no means "factory" banjos at all! I would sure love to find a Shelburne model sooner or later, but I'm afraid noone could be willing to part with such a beautiful instrument...Silvio Ferretti http://www.scorpionmusic.comCheck out a new Scorpion banjo at http://www.elderly.com/new_instrume...s/SCORP7.htm
bnjomn - Posted - 04/15/2007: 18:11:23
I have an AES "Cygnet" ca. 1980 that I believe was built by Kate Spencer. It has the narrowest and thinnest neck that I have ever seen, but is so beautifully proportioned that I can switch back and forth between it and my Ramsey Special an d have both necks feel equally comfortable in my hand. It's maple with cherry as the secondary wood and all in all a wonderful banjo.It's probably the twin of the one you describe, Mike, since it has a rosewood fingerboard and a single coordinator rod. All the other AES banjos that I've seen had dowel sticks.Cheers,Len"A man must love a thing very much if he not only practices it without any hope of fame or money, but even practices it without any hope of doing it well." G. K. Chesterton
Edited by - bnjomn on 04/15/2007 18:19:50
chip arnold - Posted - 04/15/2007: 18:49:58
Lorraine Lee hammond has an internal resonator AES which I've had the good fortune to play several times. I've owned a Reiter internal res and played a number of Bacons and although they were nice, especially the Reiter, the AES was in a class by itself. Workmanship is really fine on Lorraine's.Play with a planChip
mike hansen - Posted - 04/15/2007: 19:46:27
."It's probably the twin of the one you describe, Mike, since it has a rosewood fingerboard and a single coordinator rod. All the other AES banjos that I've seen had dowel sticks."Yep, I contacted Kate and she confirmed that it is a Cygnet model. She's gonna let me know more once I send the serial number.She also said that she is planning to put a website together about AES banjos...sounds like they were pretty cool and now pretty rare...I love the idea that these are now vintage but were once passed over because of a desire for 'vintage' banjos...i guess one day my Reiter will be vintagewww.myspace.com/ricehouserecordsBart Reiter "GALAX" Model (calf skin head)
mainejohn - Posted - 04/15/2007: 20:27:06
Alas...I'm a former owner of a Shelburne II. I bought it around 1980 at the Fifth String in Berkeley, and sold it to Steve Senerchia in Warwick RI around 1989. I've regretted it ever since. A friend bought a new Maple Leaf? model around 1982 or so and still has it but hasn't played it in 20 years. I always thought of that company as the pre-1930 Vega of the 1980's.Cheers,John Scarborough, Maine
ballbanjos - Posted - 04/16/2007: 06:21:20
I tried to buy that Shelbourne from Steve back then, but it was already sold. I wound up with a B&D that I played for years. The AES are cool banjos.Dave
mainejohn - Posted - 04/16/2007: 07:28:34
Dave: I wish you had bought it...then I would know where I could visit it once in a while!Cheers,John Scarborough, Maine
ndlxs - Posted - 04/16/2007: 09:16:28
I was simply fated to have my Shelburne. The whole story happened in April 1981 or so; I had just moved to Sacramento in my 1978 Honda Accord. I also had just bought a Martin 000-somethingorother that I had on consignment at a local music store. The Martin wasn't selling, and the Accord just had a head gasket failure that I had to borrow $750 to fix. The concept of putting instruments on credit cards was foreign to me at the time. The store I had the martin for sale at was in an old victorian in downtown Sacramento; they hung the instruments from the ceiling. So I go in on a thursday night during the jam session; no Martin! I asked the owner what happened to it, hoping it had sold, but he sheepishly said that ...get this... he DROPPED it (missing the hooks on the ceiling when hanging it back up) on the ground and busted it into a million pieces. "So I Guess I just bought it, hunh?"I confirmed that to him, but behind the counter was my Shelburne, which had just come in. "I'll take that!" Better yet, the serial number of the Shelburne was ONE MORE than my AES Northampton! The Northampton I sold to a student I had (should have kept it...), who I believe still has it. As it turns out, the guy who was selling the shelburne had bought his at the same place I had bought my Northampton, namely, McCabes in Santa Monica, where I had taken clawhammer banjo classes from Jack Aldrich and Alan Hart.Andy AlexisSacramento, California "The Pearl of the Central Valley" Buy my CDs:http://cdbaby.com/cd/pineycreekand http://www.offtocalifornia.com
mainejohn - Posted - 04/16/2007: 10:37:05
Does anyone know Margie Mirken? She and her husband Greg ran Shade Tree Instruments in Mission Viejo CA back around 1980. She used to do a column in BNL now and then. They were AES dealers and she had a Shelburne II that was for sale for awhile in their store, which eventually became her personal instrument. Just curious.Cheers,John Scarborough, Maine
vtyankee5 - Posted - 04/17/2007: 21:12:19
According to an ad in a 1974 Mugwumps magazine the Arthur L Smith banjo company address was PO Box 825 Leverett Center, MA 01054
DJMorgan - Posted - 04/18/2007: 08:57:40
The construction of banjos happened in Greenfield, near the bridge. Leverett is just a stones throw away.
BrittDLD1 - Posted - 04/28/2007: 13:17:58
quote:Originally posted by oldwoodchuckbThe makers used to come to the Fox Hollow festival in the late 1970s. I'm not sure when they started or quit but they were about the best non-custom (semi factory? whatever one wants to call it) openbacks of the era --- and the banjos were GOOD. Good value, good quality, good work all around. I was into "vintage" instruments at the time but I seriously considered buying one. I think the banjos they were making might have had some influence on my eventually going to "modern" banjos -- and of course, now those Arthur E. Smiths ARE vintage. What goes around, really actually goes around.
Edited by - BrittDLD1 on 04/28/2007 15:08:24
silvioferretti - Posted - 04/28/2007: 19:05:51
Man, you killed me... An A.E.Smith Shelburne has been a dream for me for about 30 years, and yours is an outstanding - and unique - example of what Kate Spencer and Mark Surgies could do... My clawhammer playing would not deserve it, of course, but man how I'd love to have one! So if by chance somebody out there has an AES Shelburne that he or she might want to part with... Silvio Ferretti http://www.scorpionmusic.comCheck out a new Scorpion banjo at http://www.elderly.com/new_instrume...s/SCORP7.htm
Pete Peterson - Posted - 05/07/2007: 21:39:59
I have a hybrid-- a Vega Little Wonder pot that Kate Spencer made a neck for (along the lines of a Northampton AES) back in 1976. It puts out an amazing amount of sound for such a small pot I compliment some of the members of this forum for actually spelling Mark Surgieis' name correctly. I've lost touch with him (as has Kate) -- when I made my tape for Marimac I credited Mark for some of the extra, less common verses which he sang to Wreck of the Old 97 and I learned from him. Down the road from Leverett MA is the Arthur E. Smith Memorial Bridge. Kate at one time had a picture of the covered bridge and the sign at the entrance.Pete Peterson
RWPark - Posted - 12/28/2007: 17:38:54
Wow! Finally a major discussion about my favorite banjos and I miss it by 8 months! Ah, well... as to value - a few years ago I sent pictures of my Shelburne to Elderly for their free "evaluation of value". (didn't want to sell it, just curious) The only answer I got was they didn't have anything to compare it to...just as I thought - priceless!RichI prefer to resonate internally...
silvioferretti - Posted - 12/29/2007: 15:17:37
BTW, did I tell you that I got a Maple Leaf model? Kate Spencer was so kind as to let me know someone was selling it, and I jumped at the chance and bought it. Took it home after IBMA, set it up a little, and haven't stopped doolin' an' dreamin' ever since... It's not like a Shelburne, of course, but I'm gettin close! Course I'm keeping my black cherry Northampton, as it sounds so good anyway and very different from the Maple Leaf. Too bad Kate hasn't been into building for about 25 years...Silvio Ferretti http://www.scorpionmusic.comCheck out a new Scorpion banjo at http://www.elderly.com/new_instrume...s/SCORP7.htm
RWPark - Posted - 12/29/2007: 15:55:17
Glad to hear it Silvio...Your becoming an AES collector. I'd will you my Shelburne but I've got 5 Grandchildren in line.BTW the Maple Leaf sold for $650.00 retail in 1978 and the Shellburne II for $875.00. Those were the days.RichI prefer to resonate internally...
RWPark - Posted - 12/29/2007: 16:03:06
Ouch...just did an inflation calculation and $650.00 in 1978 would be $2088.10 in 2006 dollars.I prefer to resonate internally...
silvioferretti - Posted - 12/29/2007: 17:03:52
Yep, I believe I paid about $450.00 for my first Northampton in 1978, meaning about 400,000 lire at the time (approximately the cost of a well-kept 1970 Fiat 500), then had to sell it for more than twice as much around 1994, a sum that at the time wouldn't have bought a wreck of a car anyway. Your inflation is peanuts compared to ours... OUCH!!! I love them AES banjers anyway, and still hope I'll find a Shelburne II some day...Silvio Ferretti http://www.scorpionmusic.comCheck out a new Scorpion banjo at http://www.elderly.com/new_instrume...s/SCORP7.htm
Edited by - silvioferretti on 12/29/2007 17:05:25
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On Saturday, Jan. 28, Parking Structure #2 (located on Rose Street, with the entrance on Hilltop Avenue) will have a scheduled power outage from 8 a.m. until 2 p.m. The University's Physical Plant Division will be installing a new emergency generator during this time.
Access to the garage will not be impacted, as entrance gates will be up. However, since the power outage will include both lights and elevators, causing dark areas in the facility, Parking and Transportation Services recommends that members of the University community utilize parking alternatives during the planned outage.
As always, construction is weather-dependent and the timetable is subject to change.
Members of the campus community are encouraged to tune into 1700 AM (WQKH 253) to hear campus parking and transportation information. The station broadcasts 24 hours, 7 days a week.


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It looks like The Criterion Collection has something extra special for your trick or treat bag this Halloween, as the company unveiled their October slate, and it's a great one.
Kicking things off, Roman Polanski's stone cold horror classic "Rosemary's Baby" gets the wacky C with a fresh edition on DVD and Blu-Ray. In addition to boasting a brand new restoration, the disc will feature new interviews with Polanski, Mia Farrow, and producer Robert Evans. Even more, there will be "Komeda, Komeda," a feature-length documentary on the life and work of jazz musician and composer Krzysztof Komeda, who scored the film. If you haven't seen this tale of paranoia and the occult, do yourself a favor, and buy it blind. You will not be disappointed.
From the late '60s into the early '70s, underrated director John Schlesinger's "Sunday Bloody Sunday" will hit shelves on DVD and Blu. The followup to the director's groundbreaking "Midnight Cowboy," the film is a chronicle of a middle aged doctor and a divorcée who are both sleeping with the same artist. Oh, the '70s. The meat of the extras here are new and archival interviews with Schlesinger, actor Murray Head, DoP Billy Williams, production designer Luciana Arrighi, writer William J. Mann, and photographer Michael Childers, Schlesinger's longtime partner.
Next up, one of The Playlist's Best Films Of 2012…So Far gets "the treatment" with Joshua Marston's "The Forgiveness Of Blood" entering the collection and both formats. The film takes place in Albania where traditional methods for dealing with disputes between neighbors clash with an evolving, slowly progressing society, in a powerful look at familial responsibility. It's an excellent film and we're glad to see Marston get the recognition the film truly deserved on its theatrical release, and hopefully a brand new audience will find it on home video. The disc will include an audio commentary, rehearsal and audition footage as well as, "Acting Close to Home," a discussion between Marston and actors Refet Abazi, Tristan Halilaj, and Sindi Laçej, and "Truth on the Ground," featuring new and on-set interviews with Mezey, Abazi, Halilaj, and Laçej.
The Eclipse line adds a new collection with "Three Wicked Melodramas from Gainsborough Pictures," highlighting three popular, over the top, 1940s costume dramas from the British production company during an era when realism was king. The set will include "The Man In Grey," "Madonna Of The Seven Moons" and "The Wicked Lady." DVD only folks.
Finally, Wong Kar-Wai's gorgeous and shatteringly romantic "In The Mood For Love" gets an upgrade to BluRay.


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I've been working on developing resources for Special Area teachers around the Common Core standards. As I work with teachers who teach these subjects, it's becoming apparent that while there may be a willingness, there is not a path.
I put together a Pinterest page of resources for Art teachers. I'm still adding to it, but wanted to go ahead and share it. There is still much to consider and I'll be adding to it as I find relevant resources, but I hope that Art teachers will be able to start using what is there already.
The Common Core is asking all teachers to be Literacy Support for students. If they can't read well, then everything they do will be more difficult. Those of us that are doing this work honor the fact that training in literacy may not have taken place in some of the content areas, thus we are providing as much relevant information as possible as this gets rolled out to teachers.
To access the resources, CLICK HERE.
I'll be adding additional Unit Plans / Lesson Plans and resources as I get them from teachers. Also, if you'd like to contribute to the Pinterest Page, please either message me your email address so I can add you as a contributor, or leave your email address in the comments below.
I've only been using Pinterest for a short time, but the nature of it as a "Visual Curation Tool" was too difficult to ignore as the appropriate web tool for collecting/curating web resources around Art and the Common Core. If you haven't experienced Pinterest yet, I encourage you to give it a go. It has a lot of implications for curating and amplifying information for teachers AND students!
Follow Mike on Twitter for even more resources!
Sunday, February 26, 2012
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As an art teacher, I have always incorporated into my lessons art history, world cultures, and the common bond artists across the millenium have shared. As an opponent of Common Core, I can see no advantage to having it creep into the art experience. Common Core is a government over-reach of epic proportions which will not enhance art programs, but will rather stifle the teachers, as well as the students. The Common Core wants uniformity, not diversity, and is the antithesis of individual creativity. I hope you will do more research before you encourage others to swallow this Kool-Aid.
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OTTAWA – A investigation into the federal government's loss of personal information on over 5,000 Canadians has widened to include the Justice Department.
The loss of a portable data key containing information connected to Canada Pension Plan disability benefits was initially thought to involve only Human Resources and Development Canada, which administers the program.
But those who filed complaints to the privacy commissioner's office over the data breach are now being told the incident may have included another department.
"I wish to advise you that it has come to our attention that an employee from the Department of Justice Canada may also have been involved in the incident which resulted in the loss of the USB device," says the letter.
It goes on to inform recipients a complaint against the Justice Department was filed Jan. 28.
"Our office is therefore investigating both HRSDC and Justice Canada regarding the incident," says the letter, dated Feb. 14.
A Justice spokeswoman said the department is investigating as well.
"Administrative investigations are underway to determine all the facts surrounding this matter," Carole Saindon said in an email.
"The Department of Justice is part of the investigations. Justice Canada takes the protection of privacy seriously," she said.
"It would be inappropriate to comment further while the investigations are ongoing."
The same day as the letter, senior officials from the Human Resources Department were before a House of Commons committee testifying about the breach.
No mention was made of the possibility another department was involved.
The committee was told that USB key went missing Nov. 16, two days after it was loaded with unencrypted information on 5,045 people, including their social insurance number, medical conditions, level of education and jobs.
The key was handed to an employee working on a secure floor at Human Resources who used it the next day, but then couldn't find it.
The committee heard that the search for the missing stick included an employee's home and office, and even a taxi they had taken home the day after the stick was received.
It was never recovered.
About 10 days earlier, an employee in a different division at Human Resources had also misplaced an external hard drive — that device contained student loan information on 583,000 Canadians.
That incident is also under investigation.
A spokeswoman for the privacy commissioner said at this point that investigation remains focused on Human Resources.
"We've opened a complaint against the Department of Justice in relation to the incident involving loss of the information stored on the USB key — not in relation to the other (student loan info) breach," Anne-Marie Hayden said in an email.
The idea that officials within Justice were looking at people's medical files raises a host of new questions about what the government does with people's personal information, said one of the lawyers involved in a class-action lawsuit against the government.
"Nothing good comes of having the Department of Justice look at your CPP disability pension application information," said Ted Charney.
Charney said the possibility another department is involved could change the nature of the lawsuit.
"If it turns out that this personal information has been leaked to a department who shouldn't have received it, it's an additional breach of privacy," he said.
"The motives and purpose for that employee getting access to that information is of very significant concern to us."
Since the two incidents, Human Resources has banned the use of portable hard drives and unapproved USB sticks.
They have also installed new data loss protection software designed to keep better tabs on where and how data is being moved around the department.
"The incidents are unacceptable," Ian Shugart, the department's deputy minister told the committee earlier this month.
"Sensitive personal information was stored on unencrypted portable storage devices and not properly secured. This should not have occurred."


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March 31, 2012
CHICAGO - Loyola University Chicago Athletics is proud to announce that the 27th Annual Loyola Ramblers Golf Outing will be held on Thursday, August 2, at Harborside International Golf Center in Chicago. The event provides participants with a round of golf on one of the top courses in the Chicagoland area, food, drink, and fun, all in support of Loyola Athletics.
This year's outing will feature a shotgun start beginning at 12:30 p.m. In addition to a round of golf, each participant will also receive lunch, dinner, and drinks, all for the affordable cost of $250.
Located just 16 minutes from downtown Chicago, Harborside brings championship style links golf to Chicago's doorstep. No other course in the area can combine the rugged links exterior with sculpted fairways and manicured greens that make Harborside the top choice for people to enjoy traditional links golf.
Tremendous sponsorship opportunities are also available, with all proceeds going to support Loyola student-athletes.
Those interested in playing in the Loyola Ramblers Golf Outing should contact Pat Schultz at (773) 508-2566 or firstname.lastname@example.com. For sponsorship opportunities, please contact Pat Conway at (773) 508-2766 or email@example.com.
More details will follow in the coming weeks. Please check back with www.loyolaramblers.com for more information.


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or Gargoil (g hard). A water-spout in church architecture. Sometimes also spelt Gurgoyle. They are usually carved into some fantastic shape, such as a dragon's head, through which the water flows. Gargouille was the great dragon that lived in the Seine, ravaged Rouen, and was slain by St. Romanus, Bishop of Rouen, in the seventh century. (See Dragon.)
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This 2007 3060 Regal is extremely clean and in excellent condition.The outdrives were upgraded form the composite XPD to brand new Volvo DPS-A outdrives and transom plates, as well as active X electronic corrosion system in 2014. This was a freshwater boat that has spent its life on the Chesapeake Bay until it was shipped down to west central Florida (Tarpon Springs) in December 2015 due to the owners job transfer. No expense was spared in the maintenance of this boat. Some of her options include but are not limited to Fusion Bluetooth / I pod stereo with 2 amplifiers, seven speakers, helm and transom mounted wired smart controllers. 200 watt subwoofer, all cabin LED lighting, 2 Samsung HD TVs on articulating mounts with a blue ray player that feeds one or both TV's. TV's are on an invertor system, Custom interior bedding, sheets, towels, and pillows, Corian counter-tops including dinette table,16,000 BTU AC with helm ducts, microwave, 2 burner electric stove, water & waste monitoring system,2 CO2 Detectors, Zantrex isolation transformer, 3 underwater LED transom lights, Halon Fire System,Gasoline fume detector,Transom hot / cold shower,Neutra salt system,Canvas sides / glass have been replaced in 2013,Full camper canvas included,Twin 30 amp shore power Service,Cockpit wet bar with an iso therm refrigerator,Windless with fresh water bow wash-down and new anchor chain / rode,Remote search light,LED engine room and cockpit lighting,New blowers and hoses,New hot water heater,New bilge pumps and hoses,New fresh water system with filtration and variable speed pump,Garmin 740 XS radar, fish finder and touch screen plotter,Garmin VHF,Additional depth finder,New helm seat,New cockpit carpet,Custom sun pad recently reupholstered. Motivated Sellers..... CURRENT SURVEY AVAILABLE
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The Debaters Buy the complete Season 10 on iTunes!
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A Cardiac Catheterization is a common test used by the cardiologist to learn about the patient's heart and how it is functioning. The test does not treat any form of heart disease, but allows the viewing of the chambers valves, and arteries surrounding the heart. There are two different types of Cardiac Catheterization: a Left and a Right.
A Left Heart Catheterization views the arteries around the heart to diagnose any blockages, narrowing, or defects.
A Right Heart Catheterization gives specific information about fluid pressures within the heart, lung pressures, cardiac output (the amount of blood delivered with every heart beat), and oxygen saturation. At the time of the Cardiac Catheterization, images are saved so that the results can be studied or evaluated by other members of the patient's health care team. The test itself can be finished in approximately 1 to 1 1/2 hours.
The Cardiac Catheterization is done in Beaumont Hospital - Farmington Hills' Cardiac Catheterization (or Cath) Lab located on the first floor. In the procedure room, there is a large camera, a heart monitor, a blood pressure monitor, an oxygen saturation sensor, a movable table, and many different types of supplies. There is also equipment used in case of an emergency. The staff is certified in Advance Cardiac Life Support and remain with the patient throughout the entire test. Map Floorplan
On the day of the test, the patient is usually kept without food or drink for approximately 6 hours prior to the test. They are prepared for the test in the Holding Room of the Cath Lab. There a Nurse will ask the patient to undress completely and wear a hospital gown. A heart monitor will be applied, and vital signs will be taken. The Nurse will gather a brief history of the patient, and insert an IV. Next the Nurse will prep the patient's groin area by shaving any hair in the area. This helps to ensure cleanliness and reduce the potential for infection. Both sides will be prepped, however, only one site will be used for the procedure. After the patient is completely prepped, all questions have been answered, and an informed consent has been obtained, the patient is then taken to the Procedure Room.
In the Procedure Room, the patient will be asked to slide onto a table, and attached to the heart monitor, blood pressure cuff, and oxygen sensor. Again, to help ensure cleanliness and the reduction of potential infection, the patient will be covered by sterile sheets. A mild sedative can be administered to help the patient relax, but not go to sleep. The patient will have to perform certain tasks during the test such as coughing, deep breathing, and turning his/her head to either side.
The test involves passing a long flexible catheter from the access site up into the coronary arteries. Before inserting the catheter, the physician will numb the skin area which will cause a momentary burning sensation. Even though the skin has been numbed, the patient may still feel the Physician touching or applying pressure on the area of the catheter insertion. Arteries, veins, and the inside of the Heart do not have nerve endings so the patient will not feel the catheter traveling through and in these structures. Also, the presence of the catheter inside the heart chambers does not change the heart's functions. Occasionally, the patient may feel a 'fluttering' caused by an extra or early heart beat; this is a common, but not serious occurrence.
During the entire test, fluoroscopy pictures (similar to x-rays) are taken. They are displayed on monitors so that the Physician, Nurses, and other staff members can watch the procedure at all times. When the catheter is moved to specific areas of the heart, pressure readings can be obtained, and dye can be injected to help the Physician assess the size and functioning of the heart chambers, values, and the status of the patient's coronary arteries. During the injection of the contrast dye, the patient usually feels a 'hot flash' that lasts for about 30 seconds. It is caused by the dilation of the blood vessels in the skin. Infrequently, nausea and headache can accompany the hot flash, but these symptoms are also temporary. The cardiologist may instruct the patient to take a deep breath, hold it, and cough which will improve the pictures, and help minimize the symptoms. The pictures taken during the procedure are saved, stored on CD, and may be printed.
At the end of the procedure, the catheter is withdrawn, but the sheath (the special item used to guide the catheter) may be left in if the patient requires an interventional procedure (i.e. angioplasty). If the sheath is removed, pressure is held over the site for approximately 20 minutes, to ensure that all bleeding has stopped.
Results of the test are known immediately, and the cardiologist can discuss them with the patient and the patient's family, if requested. Many times, the physician will confer with another physician if an Angioplasty or Bypass surgery seems to be indicated.
Any invasive procedure has potential complications associated with it. The risk of any major complication from a Heart Catheterization is 1 in 1,000. The most common complication is a disturbance in heart rhythm which is why the patient's heart rhythm is monitored continuously before, during, and after the procedure. Other possible complications include blood clots, heart attack, damage to the accessed artery, or hematoma (collection of blood under the skin). Every effort is made to minimize the risk of any complication, and the staff is fully prepared to treat any complication should it occur.
After the procedure, the patient will be given instructions to help minimize the potential for bleeding or any other complication. A patient is usually monitored in a room for approximately 4-6 hours, and then will receive instructions upon discharge. Fluids are encouraged to help dilute and flush out the contrast dye used during the Heart Catheterization. A follow-up visit with the Cardiologist will be made at the time of the patient's discharge.
If, at any time, the patient has questions or concerns regarding the procedure, he/she is welcome to call the Cardiac Catheterization Lab and speak to one of the staff.


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Pets of the week: It must be good to be a dog
CHARLESTON, W.Va. -- This week's pets include a dog and a cat who apparently thinks he's a dog. Chester is a 4-year-old male Abyssinian cat who lives in St. Albans with his people, Jack and Kristi Bailey and their 10-year-old twin boys Alexander and Ethan."Chester is a very active cat and will even play fetch with the boys, bringing a small ball back to them when they toss it," said Jack Bailey.As a black lab puppy, Carrgo was trained as a guide dog by the Reishman family of Hurricane, but was later released from formal training because of his overbite and stayed temporarily with a family in New York. When Nancy Reishman's husband was diagnosed with a terminal illness, the family thought, "If only we had Carrgo to help." Three weeks later, they got a phone call saying Carrgo was available for adoption again ... and he's been with them ever since. "Though this story has a very sad ending, I now have a shadow to keep me company," Reishman said. Carrgo "is truly a special dog."


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Production of hydroxycinnamoyl anthranilates from glucose in Escherichia coli
- Aymerick Eudes†1, 2,
- Darmawi Juminaga†1, 3,
- Edward E K Baidoo1,
- F William Collins4,
- Jay D Keasling1, 2, 3, 5 and
- Dominique Loqué1, 2Email author
© Eudes et al.; licensee BioMed Central Ltd. 2013
Received: 25 May 2013
Accepted: 18 June 2013
Published: 28 June 2013
Oats contain hydroxycinnamoyl anthranilates, also named avenanthramides (Avn), which have beneficial health properties because of their antioxidant, anti-inflammatory, and antiproliferative effects. The microbial production of hydroxycinnamoyl anthranilates is an eco-friendly alternative to chemical synthesis or purification from plant sources. We recently demonstrated in yeast (Saccharomyces cerevisiae) that coexpression of 4-coumarate: CoA ligase (4CL) from Arabidopsis thaliana and hydroxycinnamoyl/benzoyl-CoA/anthranilate N-hydroxycinnamoyl/benzoyltransferase (HCBT) from Dianthus caryophyllus enabled the biological production of several cinnamoyl anthranilates upon feeding with anthranilate and various cinnamates. Using engineering strategies to overproduce anthranilate and hydroxycinnamates, we describe here an entire pathway for the microbial synthesis of two Avns from glucose in Escherichia coli.
We first showed that coexpression of HCBT and Nt4CL1 from tobacco in the E. coli anthranilate-accumulating strain W3110 trpD9923 allowed the production of Avn D [N-(4′-hydroxycinnamoyl)-anthranilic acid] and Avn F [N-(3′,4′-dihydroxycinnamoyl)-anthranilic acid] upon feeding with p-coumarate and caffeate, respectively. Moreover, additional expression in this strain of a tyrosine ammonia-lyase from Rhodotorula glutinis (Rg TAL) led to the conversion of endogenous tyrosine into p-coumarate and resulted in the production of Avn D from glucose. Second, a 135-fold improvement in Avn D titer was achieved by boosting tyrosine production using two plasmids that express the eleven genes necessary for tyrosine synthesis from erythrose 4-phosphate and phosphoenolpyruvate. Finally, expression of either the p-coumarate 3-hydroxylase Sam5 from Saccharothrix espanensis or the hydroxylase complex HpaBC from E. coli resulted in the endogenous production of caffeate and biosynthesis of Avn F.
We established a biosynthetic pathway for the microbial production of valuable hydroxycinnamoyl anthranilates from an inexpensive carbon source. The proposed pathway will serve as a platform for further engineering toward economical and sustainable bioproduction of these pharmaceuticals and other related aromatic compounds.
Avenanthramide Tranilast BAHD Antioxidant Anti-inflammatory Tyrosine Anthranilate Hydroxycinnamate Biological synthesis Escherichia coliBackground
Using microbes for biological synthesis of therapeutic drugs or precursors offers an alternative production strategy to commonly employed methods such as direct extraction from source organisms or chemical synthesis. Microbial expression systems have several advantages such as reduced requirements for toxic chemicals and natural resources; consistent quality; scalability; simple extraction; and potential for higher synthesis efficiency [31, 32]. Taking into consideration the expanding number of therapeutic applications for cinnamoyl anthranilates, as well as the fact that these molecules are currently synthesized chemically or extracted from food sources [33, 34], we attempted to design a pathway for their de novo production from glucose using E. coli as a production platform.
HCBT is an acetyltransferase from the BAHD family [35], which couples p-coumaroyl-CoA with anthranilate via an amide bond to produce Avn D (Figure 1B) [36]; while 4CL enzymes convert cinnamates into their corresponding CoA thioesters [37]. We previously engineered a yeast strain that coexpresses 4CL and HCBT for the production of several cinnamoyl anthranilates, such as Avn D and Avn F, upon feedings with anthranilate and various cinnamates. This highlighted the potential of using these enzymes for the biological production of cinnamoyl anthranilates [38]. E. coli is a host of choice for the expression of complex pathways and the production of elaborate molecules such as aromatic compounds from cheap carbon sources [39, 40].
Results and discussion
Expression of Nt4CL1 and HCBT in E. coli strain W3110 trpD9923
E. coli W3110 trpD9923 strain is a tryptophan auxotroph that over-accumulates anthranilate due to a nonsense mutation in the trpD gene, which abolishes anthranilate phosphoribosyltransferase activity but does not affect anthranilate synthase activity [41, 42]. This strain was shown to be suitable for metabolic engineering because expression of genes from the shikimate pathway further increased anthranilate production [41]. We first constructed pAvn plasmid for coexpression of Nt4CL1, which encodes a 4CL that converts p-coumarate and caffeate into their corresponding CoA thioesters [48], and HCBT. To confirm that HCBT can catalyze the condensation of coumaroyl-CoA with anthranilate and produce Avn D in W3110 trpD9923, the strain was transformed with pAvn and grown in the presence of p-coumarate as a precursor. Cultures of W3110 trpD9923 harboring an empty vector were also grown as a negative control. Only in the case of the strain expressing pAvn, LC-TOF MS analysis of the culture medium revealed a peak (Rt = 11.75 min) that corresponds to Avn D by comparison with an authentic standard solution (Figure 2A). Similarly, the engineered strain produced some Avn F (Rt = 10.56 min) when p-coumarate was substituted by caffeate in the medium (Figure 2B). This result confirms the affinity of HCBT for caffeoyl-CoA. It also demonstrates secretion of Avn outside of the production host, because the Avn D and Avn F content inside E. coli cells represented less than 5% of the amount quantified from the medium (data not shown).
Biosynthesis of Avn D from glucose and titer improvement using a tyrosine overproduction strategy
Production of Avn D and precursors by engineered W3110 trpD9923 E . coli strains
Plasmids | Compounds (μM) | |||
Anthranilate | Tyrosine | p-Coumarate | Avn D | |
Empty pZS21 + pBbB5a | 1646 ± 63 | 9.3 ± 1.3 | nd | nd |
pS0 + pY | 5878 ± 311 | 6201 ± 598 | nd | nd |
pAvnD | 1564 ± 58 | 6.8 ± 0.9 | 1.0 ± 0.1 | 0.2 ± 0.1 |
pS0 + pY + pAvnD | 5780 ± 251 | 5963 ± 219 | 32.6 ± 3.4 | 27.3 ± 1.4 |
Conversion of p-coumarate into caffeate and production of Avn F using Sam5
Production of Avn F and precursors by engineered W3110 trpD9923 E . coli strains
Plasmids | Compounds (μM) | |||||
Anthranilate | Tyrosine | p-Coumarate | Caffeate | Avn D | Avn F | |
pAvnDF1 | 1498 ± 76 | 6.0 ± 1.0 | nd | 0.28 ± 0.07 | nd | nd |
pS0 + pY + pAvnDF1 | 5802 ± 298 | 6286 ± 150 | nd | 65.1 ± 8.3 | 0.07 ± 0.00 | 0.11 ± 0.04 |
pAvnDF2 | 1521 ± 44 | 2.0 ± 0.2 | 0.10 ± 0.01 | 0.13 ± 0.03 | 0.03 ± 0.00 | nd |
pS0 + pY + pAvnDF2 | 5644 ± 288 | 2503 ± 313 | 11.9 ± 2.2 | 14.9 ± 1.6 | 4.1 ± 0.7 | 0.54 ± 0.16 |
Conversion of p-coumarate into caffeate and production of Avn F using the HpaBC complex
This work is an example of biological production of valuable aromatic metabolites using a tyrosine-overproducing strategy applied to an anthranilate-accumulating strain. Considering the anthranilate titers achieved with the strain containing only the shikimate and tyrosine modules, the maximum theoretical yield for Avn D in this background would be ~5.8 mM. However, much lower Avn D titers were obtained for the strain harboring pS0, pY and pAvnD, probably due to poor conversion of tyrosine into p-coumarate as previously observed in various studies using heterologous expression of TALs [46, 49, 50], and potentially to the limited intracellular pools of coenzyme A availability [55]. It is particularly noteworthy that, because of its specificity to anthranilate as an acceptor, the BAHD acyltransferase HCBT allowed the exclusive biological synthesis of cinnamoyl anthranilates. For instance, no mass peaks corresponding to other phenylpropenoyl-amino acid amides consisting of a tryptophan, tyrosine or an L-dopa moiety — nor to hydroxycinnamate esters of shikimate or quinate — could be detected in the culture medium of our different E. coli Avn-producing strains.
The discovery that Rg TAL has L-dopa ammonia-lyase (DAL) activity is of interest and provides some opportunities for the design of new enzymes with a higher DAL/TAL activity ratio. In combination with tyrosine hydroxylase complexes such as HpaBC, such engineered DALs could be used to improve the bioproduction of caffeate from tyrosine via L-dopa and without generating p-coumarate as an intermediate, a competitive precursor for the biosynthesis of Avn F. Furthermore, the impact of expressing in our system 4CLs other than Nt4CL1 should be considered; especially in regard to production of Avn F, because Nt4CL1 is known to be less active with caffeate as a substrate compared to p-coumarate [56, 57]. Finally, our rationally designed pathway can serve as a framework for improvement of Avn production using combinatorial approaches that have been shown previously to increase tyrosine production [58]. As an adjunct to the recent development of procedures that use safe methylating agents [59], this study describes a basis for eco-friendly production of cinnamoyl anthranilates such as Avn D and Avn F and can serve as a scaffold for the synthesis of more elaborate molecules such as tranilast and its analogs.
Chemicals and enzymes
The following chemicals and enzymes were used in this study: p-coumarate, L-tyrosine, anthranilate, L-dopa, isopropyl-β-D-thiogalactopyranoside (IPTG) (Sigma-Aldrich, St. Louis, MO, USA), caffeate (MPBiomedicals, Solon, OH, USA), 3,4,5-trihydroxycinnamate (Apin Chemicals Ltd, Abingdon, UK), restriction enzymes (NEB, Ipswich, MA, USA), PhusionHigh-Fidelity DNA Polymerase (Thermo Scientific, Waltham, MA, USA), Rapid DNA ligase Kit (Roche Applied Science, Indianapolis, IN, USA). All the enzymes were used in accordance with instructions provided by the manufacturers. N-(4′-hydroxy-(E)-cinnamoyl)-anthranilate (Avn D) and N-(3′,4′-dihydroxy-(E)-cinnamoyl)-anthranilate (Avn F) were prepared as described [1, 38].
Strains, plasmids, media, and growth conditions
Plasmids and strains used in this study
Plasmid or Strain | Description | References |
Base plasmids | ||
pZS21 | pSC101; Kanr PLtetO-1 | [61] |
pBbB5a | pBBR1; AmprlacI PlacUV5 | [62] |
pBbA5c | p15A; CmrlacI PlacUV5 | [62] |
pBbE1a | colE1; AmprlacI Ptrc | [62] |
pBbE7k | colE1; KanrlacI PT7 | [62] |
Shikimate plasmid | ||
pS0 | pZS21::ydiB-aroD-aro B-aroG*-ppsA-tktA | [45] |
Tyrosine plasmid | ||
pY | pBbB5a::tyrB-tyrA*-aroC-aroA-aroL | This study |
Cinnamoyl anthranilates plasmids | ||
pAvn | pBbA5c::HCBT-4CL1 | This study |
pAvnD | pBbA5c::HCBT-4CL1-tal | This study |
pAvnDF1 | pBbA5c::HCBT-4CL1-tal-Ptrc-sam5 | This study |
pAvnDF2 | pBbA5c::HCBT-4CL1-tal-Ptrc-hpaB-hpaC | This study |
Other plasmids | ||
pSam5 | pBbE1a::sam5 | This study |
pRgTAL | pBbE7k::tal | This study |
Strains | ||
W3110 trpD9923 | W3110 [F-λ- INV (rrnD-rrnE) 1] tryptophan auxotroph, randomly mutagenized by treatment with ultraviolet radiation | |
DH10B | Cloning host | Life technologies |
BL21(DE3) | Expression host | Life technologies |
Construction of plasmids
The BglBricks cloning strategy and the BglBricks vectors [62, 63] were used for gene assembly. All the forward primers consist of a BglII restriction site at the 5′-end, followed by the Shine-Dalgarno sequence prior to the start codon. The reverse primers consist of the XhoI and BamHI restriction sites at the 5′-end. For the pAvn construct, the gene sequence encoding HCBT (GenBank: CAB06427) from [38] was amplified using the primers HCBTfw and HCBTrv listed in Additional file 2: Table S1. The PCR product was digested with BglII / XhoI and ligated into the pBbA5c plasmid [56] between theBamHI and XhoI restriction sites. The cDNA clone corresponding to Nt4CL1 (GenBank: U50845) from [48] was amplified using the primers 4CLfw and 4CLrv (Additional file 2: Table S1), digested with BglII / XhoI and ligated into the pBbA5c::HCBT construct previously digested with BamHI / XhoI to yield the pAvn plasmid.
For the construction of pAvnD, a gene sequence encoding Rg TAL (GenBank: AAA33883) was synthesized (Genescript, NJ, USA) and amplified using the primers TALfw and TALrv listed in Additional file 2: Table S1. The PCR product was digested with BglII / XhoI and ligated downstream Nt4CL1 into pAvn previously digested with BamHI / XhoI. The Rg TAL gene sequence was also ligated downstream the T7 promoter into the pBbE7k plasmid [62] between the BamHI and XhoI sites to obtain the pRgTAL construct.
For the pAvnDF1 construct, a gene sequence encoding Sam5 (GenBank: ABC88666.1) was synthesized (Genescript, NJ, USA) with the BglBricks restriction sites EcoRI and BglII followed by the Shine-Dalgarno sequence at the 5′-end, and with BamHI and XhoI restriction sites at the 3′-end. The sam5 fragment was released by BglII / XhoI digestions and cloned between the BamHI and XhoI sites of the pBbE1a plasmid [63], downstream the terminator – promoter combination sequence T1-Ptrc, to yield the pSam5 plasmid. The T1-Ptrc-Sam5 fragment was released from pSam5 with BglII / XhoI digestions and ligated downstream Rg TAL into pAvnD previously digested with BamHI and XhoI.
For the pAvnDF2 construct, the hpaBC operon, which encodes HpaB (GenBank: CAQ34705) and HpaC (GenBank: CAQ34704) was amplified from E. coli BL21 (DE3) genomic DNA using primers hpaBCfw and hpaBCrv (Additional file 2: Table S1). The PCR product was ligated into the pCR-4Blunt-TOPO vector (Life technologies, Foster City, CA, USA) and a sequenced-verified clone was cured by site-directed mutagenesis to remove an internal BglII restriction site (nucleotides 83–88) using the primers SDM-BglIIfw and SDM-BglIIrv (Additional file 2: Table S1). The cured hpaBC operon was cloned into the pBbE1a plasmid downstream the T1-Ptrc sequence. The T1-Ptrc-hpaBC fragment was released with BglII / XhoI digestions and ligated downstream Rg TAL into pAvnD previously digested with BamHI and XhoI. For the construction of the pY plasmid, the tyrosine operon in the pY1 plasmid [45] was released with BglII / XhoI digestions and cloned into the pBbB5a plasmid between the BamHI and XhoI restriction sites.
LC-MS analysis of cinnamoyl anthranilates and precursors
All metabolites were quantified using HPLC–electrospray ionization (ESI)–time-of-flight (TOF) MS. An aliquot of the culture medium was cleared by centrifugation (21,000xg, 5 min, 4°C), mixed with an equal volume of cold methanol–water (1:1, v/v), and filtered using Amicon Ultra centrifugal filters (3,000 Da MW cut off regenerated cellulose membrane; Millipore, Billerica, MA) prior to analysis. For the quantification of intracellular Avn, a cell pellet from 5 ml of culture was washed three times with water, suspended in cold methanol–water (1:1, v/v), sonicated twice for 30 s and centrifuged (21,000xg, 5 min, 4°C). The supernatant was collected and filtered before analysis. The separation of metabolites was conducted on the fermentation-monitoring HPX-87H column with 8% cross-linkage (150-mm length, 7.8-mm inside diameter, and 9-μm particle size; Bio-Rad, Richmond, CA) using an Agilent Technologies 1100 Series HPLC system. A sample injection volume of 10 μl was used throughout. The sample tray and column compartment were set to 4 and 50°C, respectively. Metabolites were eluted isocratically with a mobile-phase composition of 0.1% formic acid in water at a flow rate of 0.5 ml/min. The HPLC system was coupled to an Agilent Technologies 6210 series time-of-flight mass spectrometer (for LC-TOF MS) via a MassHunter workstation (Agilent Technologies, CA). Drying and nebulizing gases were set to 13 liters/min and 30 lb/in2, respectively, and a drying-gas temperature of 330°C was used throughout. ESI was conducted in the negative ion mode and a capillary voltage of −3,500 V was utilized. All other MS conditions were described previously [38]. Metabolites were quantified via seven-point calibration curves of authentic standard compounds for which the R2 coefficients were ≥0.99.
- Avn:
- DHAvnD:
Dihydroavenanthramide D
4-Coumarate/CoA ligase
Hydroxycinnamoyl/benzoyl-CoA/anthranilate N-hydroxycinnamoyl/benzoyltransferase
Tyrosine ammonia lyase
- CoA:
Coenzyme A.
Authors are thankful to Dr. Carsten Rautengarten for providing the Nt4CL1 cDNA clone and Sabin Russell for language editing of the manuscript. This work was part of the DOE Joint BioEnergy Institute (http://www.jbei.org) supported by the U. S. Department of Energy, Office of Science, Office of Biological and Environmental Research, through contract DE-AC02-05CH11231 between Lawrence Berkeley National Laboratory and the U.S. Department of Energy.
Authors' Affiliations
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This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


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The week in drinks |
The top ten stories published on just-drinks this week:
Having faced ever-increasing competition from the New World for decades, the European wine sector will eventually have to battle with China in the international wine market, a new just-drinks report has warned.
Heineken has launched a new global responsible drinking campaign aimed at drawing younger consumers' attention to moderate alcohol consumption.
On-trade volumes across all alcohol categories in the US fell last year, with beer suffering the most and wine the least, according to latest figures.
PepsiCo has fallen foul of the UK's advertising authorities over the term "antioxidant" used to market its Naked Juice brand.
Diageo has upped its interest in the Tequila category through the acquisition of the DeLeón brand as part of a joint-venture agreement with rap artist and producer Sean 'Diddy' Combs.
Gruppo Campari has announced a shake-up of its organisational structure and personnel changes, which includes its international MD leaving the group.
Constellation Brands has increased its year-to-date sales by two-thirds as its takeover of the Crown Imports JV dominates both its top line and bottom lines.
Beam Inc has joined forces with Justin Timberlake to rebrand 901 Tequila, which was launched by the musician and actor four years ago.
UK soft drinks maker Nichols has posted an increase in full-year sales for 2013, as gains in concentrate made up for declines in carbonate for its core Vimto brand.
Gruppo Campari's CEO has revealed that Aperol's sponsorship deal with Manchester United FC is part of a second stage of targeted international growth for the liqueur brand, after initial success in Europe.


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By The Associated Press
SILVER SPRING, Md. — Police say the gunman who took three people hostage at the Discovery Channel network's programming has died after they shot him.
All three hostages escaped safely.
Police spent several hours negotiating with him after he burst into the suburban Washington building about 1 p.m. waving a handgun and with canisters strapped to his body.
Montgomery County Police Chief Thomas Manger says an explosive device may have detonated, and the suspect may have brought other devices into the building. He said as far as he knows, the 1,900 people who work in the building were able to get out safely.


text: Hello, I have found a webserver that spits the cookie version as a float (1.2) instead of an integer as the protocol mandates. (www.alimentacion.carrefour.es) So far I have been changing line 33 in cookie.rb from when "version" then cookie.version = Integer(value) to when "version" then cookie.version = Integer(value.round) Of course every time WWW:Mechanize gets updated, I have to do the change again. How should we handle this? I am sure there has to be a better way. Thank you very much, I am really having fun using this fine piece of software. -- Eduardo Fernández Corrales || 0xEFC.com


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If scrapbooking just isn't your thing, not to worry — we're sharing five unique, book-free ways to hold onto the most special memories from your little one's early years. From themed shadow boxes to bronzed objects to a quilt made with clothes, these original ideas will help you celebrate your child's everyday milestones and save the must-have mementos. Can't stand the thought of sliding another piece of paper into a plastic sleeve? Try these five keepsake options for memories you'll remember forever!
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Over the River...Riddles are little poems or phrases that pose a question that needs answering. Riddles frequently rhyme, but this is not a requirement.From noon to 5 PM we drive
Finally at Grandma's we arrive! But going home is much more fun. We leave at 10 AM and are home by one (PM)! What happened? What Next?
See another brain teaser just like this one... Or, just get a random brain teaser If you become a registered user you can vote on this riddle, keep track of which ones you have seen, and even make your own. Comments
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text: Turning A Model Into A "Clicker" From The Last Of UsLuke Plunkett6/24/13 1:00amFiled to: fancy pantscosplaythe last of us2069EditPromoteShare to KinjaToggle Conversation toolsGo to permalink Now that the game's out, and it's rather good, you can bet we'll be up to our eyeballs in cosplay paying homage to The Last of Us. Cosplay that's going to have to work very hard to beat this effort, which transformed a model from a regular human into a "clicker", one of the worst monsters you'll face in the game. Advertisement The shoot was made possible thanks to the efforts of three people: make-up artist Jon Wilks, photographer Adrian and model/infected Emma Franks, who earlier this month visited an abandoned mental hospital in England (so perfect) and took a series of amazing photos.I am looking at these, I am hearing the noise, I am picturing her making the noise, and I am getting nervous. Advertisement The Last Of Us [JWBeyond]To see the larger pics in all their glory (or, if they're big enough, so you can save them as wallpaper), click on the "expand" button in the bottom-right corner.Fancy Pants is Kotaku's weekly round-up of the best in video game cosplay (costume play), where fans dress up as their favourite characters. Luke firstname.lastname@example.com@lukeplunkettLuke Plunkett is a Contributing Editor based in Canberra, Australia. He also runs cosplay.kotaku.com.Reply206 repliesLeave a reply


text: Retailers Are Watching You With New Tracking ProgramJenna Sauers12/28/10 5:45pm2482EditPromoteGo to permalinkGood news? Some stores are now making it easier to return unwanted items. Bad news? They're doing it by employing proprietary tracking software that displays each shopper's entire return history. Meet the Return Activity Report. You probably already have one!


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Deen De Bortoli Vat 8 Shiraz 2008, Southeastern Australia
$8.95 (621649)
Deep ruby in colour, the nose shows fruity aromas of brambleberry, vanilla, tar and smoke. Medium to full-bodied, generous with hints of tar and smoke on the aftertaste. Serving Suggestion Rack of lamb, grilled tenderloin. Discontinued at LCBO
Critic Reviews (1)
Steve Thurlow
A well structured balanced shiraz which is a step up from the 2007 vintage with its earthy smoky black cherry fruit...
Sign In to see Critic Reviews. Not a Member? Please Sign Up.Community Reviews (8)
Francois Botha
Blackberry, black cherry and spices on the nose. The wine has plenty of ripe fruit and ripe tannins, is medium-bodied, and very well balanced.
Stephan W
Perfect wine when you want to play it safe during a Christmas party with lots of people with different tastes. Was very well received by my guests. I found it pleasant to drink. Nice dry Shiraz. Tried in December 2011.


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Park Maps and Brochures:
Upcoming Events:
More than a billion years ago, the Black Mountains were formed. This mighty range of peaks once stood lofty and rugged. But over millions of years, wind, water and other forces wore down the pinnacles to their rounded, more subdued profile of today. Only the erosion-resistant igneous and metamorphic rocks allowed Mount Mitchell to retain its dramatic height of 6,684 feet.
Because of the even elevation of its ridgeline, the Black Mountain range was referred to as a single mountain until the late 1850s. Of the separate peaks that have since been designated, six are among the ten highest in the eastern United States. Although the Black Mountain range is higher, its length and breadth do not equal that of the nearby Blue Ridge or Great Smoky mountains. From the air, the range bears the shape of the letter J, and the distance between its end points—Yeates Knob and Celo Knob—is merely 15 miles.
The climate of the Black Mountains is more like that of Canada than North Carolina. Extremely cold temperatures during the Pleistocene Era allowed the plants and animals of more northern latitudes to extend their ranges to the south, but as warmer climates returned, these cold-adapted species became restricted to the highest peaks. Therefore, many of the plants and animals of Mount Mitchell are much like those native to more northern alpine environments.
Long before explorers left Europe in search of the New World, various Native American tribes inhabited the area surrounding the Black Mountains. In the mid-1700s, the tribes were joined by settlers primarily of Scotch-Irish and English origin.
In 1787, French botanist Andre Michaux journeyed to the Black Mountains to seek the region's most valuable plants so the French government could cultivate them on their royal plantations. On his botanical excursions to the area, Michaux collected more than 2,500 specimens of trees, shrubs and other plants. About the same time that his French counterpart explored the area, Englishman John Fraser collected plants from the region to introduce to his native land. It was for this botanical explorer that the most abundant tree along the crest of the Black Mountains—the Fraser fir—was named.
Though botany was the first discipline to be explored in the Black Mountains, it was physical geography, particularly the measuring of mountains, that had the greatest impact on the history of Mount Mitchell. In 1835, Dr. Elisha Mitchell, a science professor at the University of North Carolina, made an excursion to the area to measure the mountain elevations. At the time, Grandfather Mountain was assumed to be the highest point in the region, but previous trips to the area had persuaded Mitchell that the Black Mountains were higher. Through the use of barometric pressure readings and mathematical formulas, Mitchell figured the highest elevation of the range to be 6,476 feet, higher than that of Grandfather Mountain. Subsequent visits to the Black Mountains in 1838 and 1844 led Dr. Mitchell to calculate the height of the peak at 6,672 feet—amazingly, only a mere 12 feet in error of modern calculations.
In the 1850s, controversy arose about which peak in the range was the highest. Thomas Clingman, a former student of Dr. Mitchell's, and a United States senator, set the elevation of the highest peak at 6,941 feet and insisted that Mitchell had measured another peak. In 1857, Dr. Mitchell returned to the Black Mountains to verify his measurements and to support his claim. While hiking across the mountain, he fell from a cliff above a 40-foot waterfall. Knocked unconscious by the fall, Dr. Mitchell drowned in the water below. In honor of his work, the highest peak in the Black Mountain range was given his name in 1858. Though originally buried in Asheville, Mitchell's body was reburied atop Mount Mitchell a year later.
Until the late 1800s, the Black Mountains remained largely in a wilderness state. The only apparent influence of man upon the environment was a reduced animal population caused by increased settlement and hunting. This lack of exploitation of natural resources was not to last, however. By the early 1900s, extensive logging operations had denuded much of the Black Mountain range. Logging activity had expanded rapidly by 1913 and citizens began to voice their alarm about the destruction of the forest. Foremost among them was Locke Craig, governor of North Carolina from 1913 to 1917.
In 1915, a bill was introduced in the state legislature establishing Mount Mitchell as the first state park. The legislation passed both houses quickly and on March 3, 1915, the North Carolina State Parks System came into being. In appreciation of Governor Craig's efforts, the second highest peak east of the Mississippi, with an elevation of 6,647 feet and also in North Carolina, was named Mount Craig.
Mount Mitchell State Park
November - February: 7am - 6pm
March, April: - 7am - 8pm
September, October: 7am - 9pm
May - August: 7am - 10pm
Closed Christmas Day
Park Office Hours:
8am - 5pm Monday - Sunday, April - October
8am - 5pm Monday - Friday, November - March
Museum Hours
May - October: 10am - 6pm
Restaurant Hours:
Ph 828-675-1024
May 1 - August 31, 10am - 8pm daily
September 1 - October 31, 10am - 7pm daily
Concession Stand / Gift Shop:
May - October, 10am - 6pm daily


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Rocky AlphaForce Waterproof Duty Boot
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Rocky AlphaForce Waterproof Duty Boot
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Rocky® AlphaForce Waterproof Duty Boots are made with black full-grain leather and 1000-denier nylon fabric. These lightweight, strong fabrics hold up even in the most extreme working conditions.
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Whether you're looking for durable black work boots, tactical boots, a great pair of waterproof boots or superior law enforcement boots... These Rocky AlphaForce boots are the right choice to help you get the job done!
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- 6 Inches in height


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Baby Lauren arrived! We did Julie's maternity session just in the nick of time as Baby Lauren arrived just three weeks later.
Big Sister Campbell is clearly happy about her little sister arriving (you'll see her super-cute elation in the next photos) and Lauren is…in a word…perfect. I mean…can we COUNT the number of smiles this baby gave me?? Congratulations, Stoughton Family!


text: Japanese Police Use Mii Avatar Wanted Poster To Hunt Down Hit and Run SuspectJohn Mahoney2/03/09 8:40pm38EditPromoteGo to permalinkHow deeply does Nintendo's tendrils penetrate Japanese society? So deeply that this wanted poster was spotted in Kanagawa, and instead of a traditional composite sketch, what's that we have there? A Mii portrait??


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It should have been an open and shut murder case, but Mia Quinn finds out nothing about it is simple.
After a young Chinese prostitute is stabbed to death by her rich American client, the tabloids dub Dandan Yee "Lethal Beauty"—despite the fact that she was the one who ended up dead. Yet even with double standards and naked prejudice working against her, Seattle prosecutor Mia Quinn is determined to get justice for Dandan Yee.
But when a key witness goes missing and an unsavory juror shuts down deliberations without explanation, Mia fears the trial—and the law—are being tampered with.
A constellation of fresh killings has Mia and homicide detective Charlie Carlson searching for a common source and puts Mia's family in the crosshairs of a Chinese crime cabal. Meanwhile, Dandan Yee's mother has opted to take matters into her own hands . . . and the stakes get more lethal overnight.
In the midst of all this, Mia has to contend with a fifteen-year-old son who is growing up too fast for his own good and the idea that Charlie might want to be more than just friends. Can Mia and Charlie stop the murders and still keep her family safe? Or is the very act of seeking justice enough to cost her everything—and everyone—she loves?
Contributor(s) | Lis Wiehl , April Henry |
About the Contributor(s) | Lis Wiehl Lis Wiehl is the New York Times bestselling author of over a dozen novels. She is a Harvard Law School graduate and has served as a federal prosecutor in the state of Washington and as a tenured faculty member at The University Washington School of Law. She is a former legal analyst and commentator for the Fox News Channel. Visit her online at liswiehlbooks.com. April Henry Noted author Roald Dahl helped New York Times best-selling author April Henry take her first step as a writer. When April was eleven, she sent the famous children's author a short story about a frog who loved peanut butter. He read it to an editor of an international children's magazine, who then asked to publish it. April has since written several highly acclaimed mysteries and thrillers. Her books have been short-listed for the Agatha Award, the Anthony Award, and the Oregon Book Award, and translated into several languages. Two have been chosen for BookSense by the independent booksellers of America. April lives in Portland, Oregon, with her husband and daughter. |
Publish Date | Mar 10, 2015 |
Weight (lbs) | 0.6200 |
Height | 8.38 |
Width | 5.50 |
Length | 320 |
Length Unit | Pages |
Publisher | Thomas Nelson |
Price | $16.99 |
Series | A Mia Quinn Mystery |
Format | Paperback |
Language | English |
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Mule up your holiday's pics: from Facebook to Box
I'm no psychic but I bet you two things: This holiday you already took a bunch of pictures that went straight into facebook and you drank A LOT. Now you'll probably edit your photos in the morning, but it seems a shame to lose those drunken shots. What if you could save them? Let's see how you can do that using Mule. We'll see how we can make an app that pulls all our facebook photos and upload them into box.


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Reviews for When I Tell Him |
AnGellica A fan chapter 1 . 12/21/2013 Aaaaaaaaaaaaaaawe that was sooooooooooo messed. it was perfect. |
Chibis Unleashed chapter 1 . 10/25/2012 I scanned all the reviews to see if anybody had mentioned it before, but not only are Gojyo and Sanzo well portrayed, but you /nailed/ the five-year-old mentality. It is a huge pet-peeve of mine to find fics with children who behave with a comprehension way beyond their years. In many ways, adults are easy. We are adults. We get adults. But here? You get kids. And that's harder. I especially loved when you had Gojyo get him to say the mud was on him again, completely oblivious to the idea that Gojyo was just being an ass. And the screaming about not breathing. The entire time I was reading this, it was reminding me of 4-6 year old's that I know, and I can't think of another fic that has done that for me. It also happened to be an endlessly entertaining and impossibly clever story, so many, many kudos for being awesome all-around! |
RikuSora chapter 1 . 7/20/2012 Wow, that was...just wow. I cannot adequately describe how much I love this story. It's wonderful. |
azab chapter 1 . 9/24/2010 i loved it a lot |
Sweetheart Ninja chapter 1 . 6/27/2010 Of all the Saiyuki fanfics, this is the one I keep revisiting. The humor just slays me! You captured them beautifully. Brilliant! |
Tia Paes chapter 1 . 3/21/2010 This story was so amazing that I am actually shocked. The ending, PERFECT. |
pandawolf chapter 1 . 10/3/2009 It's so freakin' hilarious! Only Gojyo can make this observation! XD |
Yukino-chan chapter 1 . 6/3/2008 i love wat u hinted in e end...:D |
the.twisted.queen chapter 1 . 2/5/2008 Oh wow, now this fic was absolutely precious. Honestly, I thought I was either going to die of the cuteness, or of sheer laughter. Beautiful! |
Eyes of Shinigami chapter 1 . 11/26/2006 *is completely and utterly in awe of your awesomeness* This story was one of the best I do believe I have ever read. You are truly an awe-inspiring writer. Woof. Your imagery was vivid, and the setting was perfect. But most of all, I have to say that your characterization of Gojyo was what sold me. I don't believe I've ever seen him portrayed this way, and that's a damn shame. It gives him a deeper side and makes him appear as more than he is so often pictured as. And it just seems so damn appropriate that he's the one who finally gets Sanzo and Goku together, especially with the way your portrayed him. The closing paragraph was definitely my favorite, because it was a very profound thing to say. I was impressed. Again, you are amazing. This is going on the faves, as well as my fave author. You have spellbound me. Thanks for a truly great reading experience. -EoS |
dragonfly-affinity chapter 1 . 7/13/2006 Aw man! That was really good! Sweet and cute - and just like Gojyo! -winks- Sankyuu! -glomp- Have to fav this - it was just so good! Yatta! Dragonfly x |
Ryuniyo chapter 1 . 5/4/2006 This is just such a wonderful piece. I'm speechless by the very end. It's unique, it's creative, it's sentimental. I love it. |
Blahsblah2001 chapter 1 . 2/12/2006 Awesome. I'm faving this definitely. It's so funny! I love the thought of Goku as a little kid. But there's some super- huge paragraphes that are kind of hard to read on a computer screen, you might wanna break those up. _melissa |
Reiya Inc chapter 1 . 2/1/2006 Amazing. I love every little bit of this fic, my review can't do justice to it. Please continue writing Saiyuki fics! -Reiya |
Katherine4 chapter 1 . 1/20/2006 Oh *wow* oh *wow* oh *wow* That was STUNNING. Ohmigod, I am in awe. I am speechless, utterly overwhemled by your TALENT. Oh *wow* *adores madly* |