text:
Atrial fibrillation is the most frequent sustained arrhythmia with a lifetime risk of 20-24% and is a significant cause of stroke, and other morbidity and mortality. There is strong evidence for heritability of AF, with a frequent intergenic chromosome 4 locus (4q25) being recently associated with AF in ambulatory populations. We have recently demonstrated that the same SNPs in the 4q25 locus, are also associated with new-onset postoperative AF in replicated cohorts of Caucasian patients after cardiac surgery. Thus, the genetic mechanisms of ambulatory AF and postoperative AF appear to be aligned, however, the mechanism(s) have not yet been identified. We will use the perioperative cardiac surgical environment, with its availability of atrial tissue and frequent AF phenotype to determine the biological mechanism(s) of the association between 4q25 genomic variation and AF. Our overall goal is to identify the genetic and molecular mechanisms whereby genetic variation in the 4q25 locus causes atrial fibrillation. In order to achieve this goal, we propose examining hypotheses for the association of 4q25 variants with AF: 1) We hypothesize that 4q25 variant(s) cause altered primary protein structure responsible for increased risk of AF. In order to identify 4q25 variants that lie within known and novel coding sequences we will measure novel atrial poly-A transcripts using Solexa sequencing of cDNA tags. We will then genotype all polymorphic coding variants in over 1900 previously collected cardiac surgical patients to identify all 4q25 coding variation associated with postoperative AF;2) We hypothesize that 4q25 variants cause alternative splicing or differential expression of cis mRNA transcripts. We will identify 4q25 transcripts that are either differentially expressed or alternatively spliced, depending upon 4q25 AF-associated genotype, by mapping the 4q25 poly-A transcriptome of the human atrium using a structured cohort of 40 patients with and without postoperative AF, and Solexa mRNA sequencing;3) We hypothesize 4q25 variants cause AF by regulation of mRNA translation by miRNA or other non-coding RNA. We will perform studies to identify non-coding RNA sources of regulation of 4q25 mRNA translation by resequencing all identified atrial poly-A and non poly-A RNA transcripts within 4q25 in the same structured cohort of 40 patients with and without postoperative AF. We will integrate the findings from the transcript and sequencing efforts to test the hypothesis. By performing these studies we will provide new insights into the molecular mechanisms that initiate AF. These insights may facilitate the development of novel therapeutic strategies to alleviate the burden of AF in the community, notably in the aging population.
Atrial fibrillation is the most frequent sustained arrhythmia with a lifetime risk of 20-24% and is a significant cause of stroke, and other morbidity and mortality. An intergenic chromosome 4 locus has recently been associated with AF. We have demonstrated that the same 4q25 locus is also associated with new-onset postoperative AF after cardiac surgery. However the mechanisms underlying the association of the 4q25 locus and either ambulatory or postoperative AF has not yet been identified. We therefore propose to use the perioperative cardiac surgical environment, with its ready availability of atrial tissue and frequent AF phenotype to determine the biological mechanism(s) of the association between 4q25 genomic variation and AF.
Simonini, Marco; Lanzani, Chiara; Bignami, Elena et al. (2014) A new clinical multivariable model that predicts postoperative acute kidney injury: impact of endogenous ouabain. Nephrol Dial Transplant 29:1696-701 |
Frey, Ulrich H; Muehlschlegel, Jochen D; Ochterbeck, Christoph et al. (2014) GNAS gene variants affect ?-blocker-related survival after coronary artery bypass grafting. Anesthesiology 120:1109-17 |
Fox, Amanda A; Nascimben, Luigino; Body, Simon C et al. (2013) Increased perioperative b-type natriuretic peptide associates with heart failure hospitalization or heart failure death after coronary artery bypass graft surgery. Anesthesiology 119:284-94 |
Fox, Amanda A; Marcantonio, Edward R; Collard, Charles D et al. (2011) Increased peak postoperative B-type natriuretic peptide predicts decreased longer-term physical function after primary coronary artery bypass graft surgery. Anesthesiology 114:807-16 |


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text:
Property: Roberts Ranch Conservation Easement
Priority Area: Laramie Foothills (map)
Size: 4,960 acres
This conservation easement is not open to the public. It is a central feature of the Livermore Valley and is visible from US Highway 287 between Fort Collins and the Wyoming state line to the north. The Roberts family has a long history in this valley, beginning with the original homestead in 1874. Members of the family are continuing their ranching legacy into the 21st century with this sustainable cow-calf operation. Also protected in this easement are areas of historical interest such as tepee rings, a portion of the Overland Trail and at least one buffalo jump. It is also significant to wildlife because it is situated near over 14, 000 acres of state and locally protected lands thus increasing the area available to wildlife for migration, resting and feeding.
Type of Acquisition | #Acres | Property Value |
Partnerships Bargain Sales Donations |
Date Acquired |
Public Access |
Conservation Easement Phase 1 | *4,960 | $ 3,000,000 | Larimer Co - $ 200,000 Fort Collins - $ 1,800,000 GOCO** - $ 889,500 TNC*** - $ 1,500 Landowner - $ 109,000 |
2004 | No |
* Since this Phase I purchase of the Roberts Ranch, which Larimer County participated in, the remaining 11,971 acres of the Roberts Ranch has been put under conservation easement. This Phase II protection was one part of the larger Laramie Foothills Mountains to Plains Project, a partnership effort that received $11.6 million from Great Outdoors Colorado to protect over 55,000 acres in this area.
** Great Outdoors Colorado
*** The Nature Conservancy
When only the development rights of a property are purchased, as in the case of a conservation easement, any future development of that land is limited. The landowner continues to manage the property, and the land remains on the tax rolls. Land with a conservation easement is not generally open to the public because it is still in private ownership.
* This conservation easement is monitored by Larimer County Open Lands.
To ensure that these properties remain in agricultural uses in perpetuity.


text:
Three stages, 35 local bands, a 2,500-capacity mansion overlooking downtown Tijuana complete with pool: bordertown indie bombs away for the second annual All My Friends Music Fest.
Held at a private residence known as the Millionaire's House, the place belongs to a business tycoon who earned his bling by supplying much of northern Mexico with the polyethylene that grocery stores here run through with little regard to its 1,000-year lifespan. (Seriously, they often toss even the toothpaste in its own sack.) He now lives in Italy and left the keys with his son, who proudly (smugly?) described his dad as a plastic bag baron. Junior now shares the eight-bedroom norteño nouveau-riche palace with just one friend and banks extra cash by renting out the yard for the occasional rave or music festival like AMF.
We knew we were in for an all-day ordeal from the get-go. Doors opened at 1 p.m. and even though the last act wasn't scheduled to play until 3:30 a.m. our people showed up at 2 in time to catch the first band, which wound up not going on until 5 or so.
So the group splintered. Some lounged by the pool in the sun; those with swimsuits toyed with actually getting in. And even though coorganizer Martha Preciado promised free beer to any gringo who did, no one made it past posing for photos on the high dive. Others killed time by roaming around the outskirts of downtown Tijuana or strolling through whatever happened to be going on in nearby Teniente Guerrero Park, a block of urban greenery that's usually the site of live impromptu homages to Selena and ongoing checkers tournaments.
The rest compensated for the lagging beer vendors by going on OXXO runs for mini bottles of Corralejo, while I found myself observing the various realms of Tijuana hipsterdom (did someone say mipsters?) as they slowly but surely strutted in. Their shoes, mostly, apparently, randomly. And the girl with cardboard sign tied to her backpack advertising she had single cigarettes for sale.
By sundown, the grounds had filled with some 1,400 bodies, according to the organizers' estimates, and the spirit of the fest finally presented itself. This was a giant house party, orchestrated by the fiesta-fiend spawn of parents who were off sailboating in St. Tropez or martiniing in Monaco or something.
Not too far from the truth, AMF fell together in 2010 when founder Argenis Garcia, a 26-year-old writer and photographer, returned from Coachella with his sister, broke and in need of money to send her back to school in Barcelona.
"I decided that the only way I could raise funds to help my sister was to bring all my friends together and throw a house party," he said.
They held it at their own place, which they were in the process of moving out of. The lack of furniture made room for three stages, one in the living room, one in the kitchen and a DJ setup in one of the bedrooms.
"We had more than 500 attendees, with bands like VisViva, El Hijo de la Diabla, a really special set by Ibi Ego in the kitchen, Jay Liquid, Machino and Al-B where there too. The party ended at 7 in the morning (when) the sun came up."
The deeper motivation for AMF was that Argenis was seeing a new generation of local bands not receiving the exposure he felt they deserved and wanted to do something about it. He describes it as a community-built festival that's not only about the acts but the family and friends who helped organize the festival from the get-go, hence the name. Even his mom was there last year selling tacos to the security guards and the bands. This year, his sis dropped in unannounced from New York, the Kanye West T-shirt he's wearing here alongside Martha in tow.
Aside from nearly tripling its turnout, AMF 2011 had caught attention from press and bloggers in Spain, Mexico City and the U.S. Not bad for its second installment. And perhaps it's a complete coincidence, what with the Tijuana haute cuisine scene apparently being the flavor of the season among New York media circles, but MTV spent a decent chunk of its summer in Tijuana recording a video series on the homegrown ruidoson movement that starred Maria y Jose and Los Macuanos, as well as spots with Nortec Collective's Bostich + Fussible, pyschojazz act Madame Ur y Sus Hombres and Sonidero Travesura (none of whom were part of the AMF lineup, by the way).
The DJ sets and smaller, intimate acts like Pek Pek and Elephant Woman happened on the balcony alongside the pool, while the more hardcore bands Hijo de la Diabla, Mae Machino and San Pedro el Cortez played in a semi-subterranean concrete bunker at the back of the property. Upstairs, on what looked to be a rooftop tennis court enclosed by barbwire-crowned chainlink (tres TJ), were shoegaze acts Loopdrop and Shantelle and headliners Bam Bam and Juan Cirerol. The bands were staggered between the two latter locales, but thanks to the lack of any sort of set list posted anywhere no one really knew who was playing when and where.
Memorable moments vary depending on whom you ask. For Argenis, it was a tie between Mae Machino's reunion after a six-year hiatus and Juan Cirerol's acapella version of "Crema Dulce," thanks in part to the lack of a sound system because the curfew for the generator had come and gone but Juan decided to keep playing.
For San Diego CityBeat editor Peter Holslin, it was Dani Shivers' "lo-fi goth pop."
"Wearing black eye shadow and a thin white shawl, she looked mysterious as she laid out warm synth chords and crude dance beats and cooed into the microphone. At once sinister and childlike, her performance was downright mesmerizing."
San Diego Reader's Chad Deal said Celofan made him "feel like a quixotic high school freshman at the Epicenter again. Reminded of Sunny Day Real Estate, Cold Weather Rescue, and 'Daydream Nation'-era Sonic Youth, I had the sudden compulsion to write fumbled love notes on Myspace to a shy brunette in heavy-handed eyeliner who smokes Kamel Reds and always wears the same beat pair of black Converse low-tops."
Personally, the evening climaxed with San Pedro el Cortez's hecho-en-Mexico melange of garage and surf rock. Not only was one of the guitarists wearing a sequined cocktail dress that resembled that which I wore behind the bars of a Tijuana jail a couple years ago, the band had taped fireworks to their guitar necks which they of course ignited and sprayed at the audience during their last song. Someone actually got it on video. A mosh pit ensued, instigated by one of Turista Libre's own, Max. ¡Ahuevo, Max!
Also among the crowd was Winston Rivas, a reporter for Austin Vida and the Latin American music corespondent for Red River Noise. He's also involved in the organization of a very significant American music festival which he asked remain unnamed. His fave of the evening was Shantelle, "a gorgeous set of shoegaze, everything from the razor sharp keyboards/synths, the funky bass line to Julio Palido's tender voice. The whole set I felt was being dipped into a glossy fantasy filled with shimmering lights and '90s romance and I never wanted to leave. This guys are Mexico's biggest hidden gem."
His favorite set, however, was Bam Bam: "A psychedelic furry of screeching synths, pounding drums and galloping guitar riffs. I knew Bam Bam was good but after seeing them live I was reassured what I already knew. They are Mexico's rock band for the next decade."
Summing up the fest in general, aside from a few organizational flaws and the somewhat awkward venue (a park would have been better), Winston felt the AMF people should be happy with how far they've come in just a year. Very few cities in Mexico can claim they have 20-30 solid indie bands, he said, and that's not even including the one's who didn't even play the festival (Maria y Jose, Los Macuanos). So this was a reaffirmation for the people of Tijuana that an indie scene does exist, and for the outsider it was a moment to take notice.
There are hundreds of festivals every year but very few capture an accurate portrait of their scene, he said.
"Does Coachella really represent Indio? Does ACL really showcase the real Austin? No. This may not have been the biggest festival but I can't recall where I've had a better time. This was a Tijuana festival made by Tijuana people for Tijuana people.
"Plus, where else can you get a big-ass cup of Jack and Coke for 35 pesos?"
Bien dicho, Winston. Bien, bien dicho.
Before the fest, the turistas fueled up on chicken drenched with Mexico's quintessential chile-chocolate sauce that's made up of no fewer than 20 ingredients, mole. Perched on the edge of a roundabout on Paseo de los Heroes in Zona Rio, La Casa Del Mole looks like a Oaxacan spin on "Swiss Family Robinson," an atrium with huge skylights, green anythings and everythings everywhere, be it paint or actual foliage, a live piano on the weekends and an actual waterfall that makes it easy to forget you're not only indoors but only a mile or so from the ol' U.S. of A.
Lineup: Juan Cirerol y Martin Del Prado, Mae Machino, Mentira Mentira, Loopdrop, Shantelle, Deck B, Vis Viva, Celofan, San Pedro el Cortez, Electric Healing Sound, Dani Shivers, La Diabla, Late Nite Howl, Perros Cobardes, El Hijo de la Diabla, Inkjet, Dasein, Krylon, Machino, Sweet Lullaby Toyland, Siete Catorce, Al-B, Elephant Woman, Santos Balcones Durango, KPTN, Pek Pek, The Kunt Set Duo.


text: The Tetris wiki last edited by Yummylee on 12/17/14 07:04PM View full history OverviewTetris is a video puzzle game originally designed and programmed by Alexey Pajitnov in June 1985. Since its release it has gone on to become a jewel of the video game industry with appearances upon nearly every console since its release.Although the game has had many successful spinoff's such as the SNES classic ' Tetris Attack', the original Tetris concept has barely changed after 20 years, with only minor improvements and fine tweaks being made to its gameplay and design. The franchise continues to make healthy sales despite its age. 23 years since its debut, its clear that the Tetris franchise is here to stay.OriginThe original title screen of Elektronika 60 version.Tetris originated from a series of puzzles called Pentomino, where the goal was to fill an 8x8 area with the help of various shapes that consist of five square blocks, without leaving any spaces. It was a three player game where players would take turns to place the various shapes, and the person to place the last piece would win. Alexey Pajitnov took this simple board game, and made two key changes. First, he changed the pentominoes to tetraminos by reducing the amount of squares of each block to four, and secondly, he added the all important time element that makes Tetris so popular.In June 1985, Tetris was created by Pajitnov on an Elektronika 60 and soon after an improved MS-DOS version, with partner Dmitry Pavlovsky ,and then ported to the IBM PC by Vadim Gerasimov. Tetris started to spread all over Moscow, it was then brought to Hungary, where Hungarian programmers ported Tetris to Apple II and Commodore 64. This original Elektronika 60 version is available to download courtesy of Gerasimov here.The game made a huge impact in Europe for a game from such small beginnings, and many large companies were eager for Pajitnov to sell them the rights for the tetris game distribution. Eventually Mirrorsoft UK and Spectrum Holobyte earned the rights to creating computer versions of Tetris. It did not take long for the rest of world to catch on, and it became the best-selling computer game in England and USA in 1988.The CreatorAt first Pajitnov did not earn a dime from his creation; USSR copyright law meant that all the profit went to the government of the USSR and the Eastern Bloc countries. He only started profiting from his creation in 1996 when he and Henk Rogers formed The Tetris Company.Pajitnov has since gone on to create the popular puzzle game franchise Hexic, which once came free with every Xbox 360 Premium package. He has since left Microsoft in 2005, and been rumored to be working with Wildsnake Software.


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text:
Heat centre Quintin Laing has been voted captain by his teammates. He'll wear the C for the third season in a row.
Heat notebook: Laing named Heat captain, Piskula and McCarthy assistants
By Sports Reporter - Abbotsford News
Published: November 01, 2012 2:00 PM
Updated: November 01, 2012 5:34 PM
In a move which surprised absolutely no one who follows the team, Quintin Laing was named captain of the Abbotsford Heat on Thursday afternoon.
The 33-year-old centre from Harris, Sask. will wear the C for the third straight season with the Heat.
The AHL club had gone captainless over the first three weeks of the regular season, as head coach Troy Ward wanted his players to gain a bit of familiarity with each other before selecting a leadership group. The players held a captaincy vote earlier in the week.
"It's the most prestigious way to give it out – to be voted captain by your peers," Ward said. "To me, it's one of the highest honours you can give in sport. It's better than winning."
Laing joined the Heat early in the 2010-11 season, and was named captain just over a month later. He was voted captain in 2011-12 as well.
"It's A to Z," Ward said, reflecting on Laing's leadership qualifications. "He's a father, he's married, he's played in the NHL, you can just go on and on and on. He's been through a lot of experiences in life, and he has a lot to lend on and off the ice. And he's one of our hardest-working players."
Defencemen Joe Piskula and Steve McCarthy were voted assistant captains. Piskula, a third-year member of the Heat, is known to be a vocal leader. McCarthy, a newcomer this fall, has quickly established himself as a respected presence in the locker room.
"He leads by example," Ward said of McCarthy. "He has a very mature way about his preparation."
Laing, Piskula and McCarthy are all considered "veterans" according to AHL development rules, due to the fact they've each played more than 320 professional games. The Heat have six vets and are only allowed to dress five, which means that one of their letter-wearers could be up in the press box on any given night.
Ward said they won't transfer the C if/when Laing is scratched, nor will they share the A's.
The Toronto Marlies visit the Abbotsford Sports and Entertainment Centre for a two-game set this week (Thursday and Friday, 7 p.m. both nights). It's their first trip to Abbotsford since the second round of last season's Calder Cup playoffs, where they eliminated the Heat four games to one.
The Marlies return many familiar faces, including 2009 first-round pick Nazem Kadri, promising puck-moving defenceman Jake Gardiner, and goalie Ben Scrivens, who was a particular Heat nemesis in that series.
Toronto has also added prolific AHL point-producer Keith Aucoin, who led the league in points per game (70 points in 43 games) with the Hershey Bears in 2011-12 before spending the second half of the campaign with the Washington Capitals.
Ward views the Marlies games as a barometer to assess the Heat's progress and areas for growth.
"The first four games of the season were kind of exhibition – I didn't look at them any other way, because we didn't play anybody before that," he analyzed. "We weren't sure what we were going to have, and we just wanted to teach and grow. Then we had the little (three-game) road trip, which I thought was going to build some character.
"Now these next four, I just look at as benchmarks. We're going to play a real good team in Toronto with a lot of depth and some NHL players there. And then we're going to play Oklahoma City (Nov. 9-10), who obviously have a lot of NHL players. We're going to find out where we stand."
Heat centre Paul Byron, who had been sidelined since training camp with an upper body injury, returned to practice on Tuesday and Wednesday. But Ward ruled him out for the weekend, saying "he's a long way away yet."
Heat forwards Greg Nemisz (lower body) and Lance Bouma (sprained right knee) are still out.


text:
Mugshots Planet is the number one source of background safety information for people of Hong Kong and around the world who will be traveling to or working in the United States.
Ying Wong (英黄) is the creator and acts as advisor to the site. While working in the United States she was a victim of a violent crime. The perpetrator was a neighbor who had many convictions previously for violent offenses. He was not required by law to make notice to all neighbor of his criminal past. Until this changes the only way to stay safe is to inform yourself about others.
While no longer living in the United States, Ms. Wong has created a resource for people of Hong Kong, China and elsewhere to inform themselves of the dangers of that country. Already many crime have been prevented such as murder, rape and assault.
It has also developed into a valuable resource for people who need to check on the background before hiring someone to take care of children, care for elderly parents or before meeting someone from a dating website. The website has also been used by charities that want to keep the wrong people away from children and prevent fraud.
US Crime Statistic 2012
Violent Crimes: 1,214,462
Murder: 14,827
Rape: 84,376
Robbery: 354,520
Assault: 760,739
source: FBI Uniform Crime Report 2012
US Crime Statistic 2011
Violent Crimes: 1,203,564
Murder: 14,612
Rape: 83,425
Robbery: 354,396
Assault: 751,131
Weapons: 159,020
source: FBI Uniform Crime Report 2011


text:
How might the son of the CEO of a medium-sized manufacturing firm succeed as his father's successor?
Allen Lane had owned and operated Plas-tek Industries, a plastics fluid-flow products company, for nearly 30 years. After several failed attempts to bring in a new partner, Allen's son, Julian, suggested that he was interested in pursuing this opportunity. This case presents students with documents and financials that surrounded the proposed deal between father and son, as well as a discussion of their different management styles, in order to highlight the issues that faced both parties.
Case ID: 120408
Contact us by e-mail at Columbia CaseWorks or 212-854-1796.


text:
Full profile →'">
The author is a Forbes contributor. The opinions expressed are those of the writer.
The warmer temperatures and springtime blooms can only mean one thing: wedding season. You've registered for china and prepared seating charts for the big day, but your nuptials don't end after you exchange vows. Now it's time for one of the best parts of newly wedded bliss to begin—the honeymoon. With options ranging from the sunny tropics and exotic European cities, it's not always easy to narrow down just the right destination for one of the most memorable vacations of your life. But the editors at Forbes Travel Guide are here to help—we scoured the globe and found 10 pristine honeymoon hotels where you and yours can bask in your recent matrimony.
Europe has long remained a popular choice for romantic escapes, and southern Greece's Peloponnese peninsula is home to Amanzo'e, a new Aman Resorts outpost that opened last fall—and it doesn't disappoint. Perched on a hilltop encircled by olive groves and overlooking the glistening Aegean Sea below, the 38-suite resort was designed by American architect Ed Tuttle and boasts an outdoor reflection pool, library (complete with various books on Greek history) and its very own private beach club.
But the Mediterranean isn't for everyone. For couples with more of a penchant for the tropics, head for Sugar Beach, A Viceroy Resort. Situated on St. Lucia's west coast along the Caribbean Sea, the resort is surrounded by 100 acres of rainforest and prides itself on being eco-friendly. Post up in one of the whitewashed villas—each complete with a private plunge pool—and ogle at the stunning views of the Pitons (two volcanic spires that rise above the Caribbean) or Anse des Pitons beach.
If you fancy a more gastronomic getaway, The Inn at Little Washington is the place to stay. Chef and proprietor Patrick O'Connell's Forbes Travel Guide Five-Star inn and restaurant sits in the beautiful countryside of Northern Virginia (about 70 miles from Washington, D.C.), and is as romantic as it gets with lush gardens, attentive yet discrete service and impeccable cuisine. If you want to explore the area, the concierge can help you set up tours of nearby wineries or hikes in Shenandoah National Park. —Caroline Patek and Hayley Bosch


text:
The Angels can score in bunches, as they showed again Friday, when they amassed nine runs for the second straight game. The question is, will they have enough pitching to win high-scoring games?
They didn't in Friday's 13-9 loss to Kansas City, when C.J. Wilson was rocked for eight runs and eight hits in 2 2/3 innings, and they didn't in Thursday night's 10-9 loss to Texas, when Jerome Williams couldn't make it out of the second inning.
The Angels have a 7.26 earned-run average in 25 spring games — a full run worse than any team in baseball — and of their five starters, only Joe Blanton has had a decent spring.
Ace Jered Weaver has a 10.13 ERA in three starts. Tommy Hanson has an 8.25 ERA in four starts and was pulled from his last game after three innings because of a tight triceps. Wilson has a 7.11 ERA in four starts. Jason Vargas has a 6.00 ERA in four starts. Blanton has a 3.86 ERA in two starts.
If this were early March, there would be no reason to panic, but the season opener is nine days away. Weaver and Wilson have only one more exhibition start; Blanton, Vargas and Hanson have two more starts.
"With our rotation in particular, yes, I'm concerned," Manager Mike Scioscia said. "Some guys aren't quite where they need to be. I sure hope as we get to the latter stages of our work in Arizona and into the Freeway Series, we'll see some guys come alive and repeat some pitches."
MLB Headlines
Mike Scioscia: Angels pitching struggles a concern
Los Angeles Times | Mar 23


text:
...by Upgrading Their Network Analysis Appliance
Users Can Identify at Risk Devices Anywhere in Their Network Within Minutes
ANNAPOLIS, Md.--Sept. 14, 2005--Netcordia, a leading provider of network analysis tools, today announced a new diagnostic feature that will test all devices on a network for the remotely-exploitable vulnerability that Cisco announced last week. The flaw is on Cisco's Firewall Authentication Proxy for FTP and/or Telnet Sessions feature in specific versions of Cisco IOS software. If the flaw is not fixed, it could allow hackers to take over IOS-based devices, or launch Denial of Service (DoS) attacks against them.
Netcordia promptly wrote the new feature for its NetMRI network health analysis appliance late last week after receiving a request from a large customer, which wanted to determine as quickly as possible whether the routers on its network were vulnerable. The new feature leverages Netcordia's Configuration Policy Analysis capability and allows NetMRI to test all devices on a network within a matter of minutes, allowing the network manager to fix the flaw before it becomes a serious problem.
"Netcordia provided a quick response," said Nhan Vo, director of enterprise network solutions, Duke University Health System. "This shows how NetMRI is valuable to large enterprises like us in detecting and identifying vulnerabilities, as well as providing a quick inventory for mitigation."
"The flaw was announced late last week, and within hours we had a customer requesting that NetMRI's configuration audit capabilities automate the identification of vulnerabilities across his thousands of devices," said Frank Pittelli, vice president of engineering for Netcordia. "With NetMRI's built-in capabilities providing proactive analysis of network infrastructure, it was a simple matter for us to quickly provide the template for auditing, specifying and locating the exact devices at risk."
About Netcordia
Netcordia develops NetMRI, a network analysis appliance. NetMRI is the most comprehensive automated network diagnostic tool for enterprise and government networks. This "network expert in a box" allows a network engineer to easily and quickly identify issues with respect to VoIP, wireless, VPN, VLAN, and IP within the network. Netcordia has been recognized as one of the top companies to watch in network management by Network Computing and one of the Fierce15 top emerging companies in IP Telephony by FierceVoIP. ( www.netcordia.com ).


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Queens of the Stone Age are back from a too long hiatus with a hard rockin new single. QOTSA seem to be back to their roots with "My God Is The Sun" with Josh Homme delivering some sexy vocals.
This is their first release from the upcoming '…Like Clockwork' which will be out in June. The album includes guest appearances from Dave Grohl (of course), Trent Reznor, Elton John ( who also appears on the new Fall Out Boy) record and former bassist for the band Nick Oliveri. The last one irks me a bit because as you QOTSA fans may know, Oliveri was kicked out of the band in 2004 by Homme for "partying too hard" and oh yeah, (allegedly) beating up his girlfriend. Nick only provides vocals on the album, and has rejoined their other band Kyuss.
I still have high hopes for …Like Clockwork, no matter who's on it. What do you guys think of the first single?


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Joe Gandelman: The Republican race for non-compassionate conservatism
Will the Republican Party's 2012 national rout have an impact? Will it become more a moderate (excuse the "dirty" word) conservative party that tries to inch back to George W. Bush's stated goal of a more "compassionate conservatism" that would appeal to growing, Democratic-inclined demographics? As Tony Soprano said: "Fuhgeddaboudit!"
Amid signs of looming Republican political civil war between purity-demanding conservative activists and a political establishment that seeks to enlarge the party's current perceived "MEMBERS ONLY" tent, there seems to be a race among Republicans to prove who has the least empathy and who will be tougher, no matter what the consequences (to groups that don't vote overwhelming Republican).
Ronald Reagan's smiling "Shining City On the Hill" has been replaced by a scowling "You Give Us What We Want or We'll Level that Hill."
Sen. Lindsay Graham blasts President Barack Obama's nomination of former Republican Sen. Chuck Hagel as an "in your face nomination," but the reality is this: to millions of Americans, today's Republican Party has become the 24/7 "in-your-face" political party.
Many American independents, centrists, moderates and 20th century style conservatives are now in a state of near political grief. They sadly watch as a party that offered substantive alternatives to govern is morphing into a political party seemingly in a state of perpetual filibuster, seeking ways to provoke political brinksmanship, looking for ways to confront — while appearing to kowtow to its most ideologically intolerant rightward faction and polarizing conservative talk show hosts.
A government shutdown? Give us what we want, or it's about time we had another one (forget about the chaos it'd mean to not just the government but government services, funding and to millions of Americans). Default on the debt limit? Slash spending the way we want or those bills won't be paid — and it won't be as bad as you "libruls" think and might even help the country (forget about the wide variety of experts, including conservative economists, who predict it'd be catastrophic to the American and world economies).
The problem for the GOP is that its courage-challenged politicians won't stand up to the Tea Party, so the soggy tea bag is waving the elephant. According to Rasmussen, only 8 percent of voters now say they are members of the Tea Party, down from a high of 24 percent in April 2010. The Tea Party now has a limp 30 percent favorable rating and an unhealthy 45 percent unfavorable rating.
Some traditional conservatives are increasingly alarmed by the nihilistic tone of their party and they're speaking out. For instance, conservative blogger Doug Mataconis writes that his party now offers two choices: "Either the nation moves in the direction that those who advocate it want it to, or it burns. There's no room for compromise, no room for debate other than on the terms already set. This is not the philosophy of a party that wants to govern, and it's not the philosophy of a party that is going to last for an extended period of time in its present form. It is, in the end, a philosophy of anarchism in which one really doesn't care what happens."
Hint to the GOP: If politics ain't bean ball, the debt ceiling ain't the fiscal cliff. It's the fiscal Grand Canyon. The debt ceiling is where craven political gamesmanship and blatant partisan power-plays can shove the United States and the world into a major financial setback.
If that happens, then in future national elections all of Rush Limbaugh's listeners and all of the Tea Party's activists won't be able put the tea-guzzling Elephant Dumpty back together again.
Joe Gandelman is a veteran journalist who wrote for newspapers overseas and in the United States. He can be reached at email@example.com.


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People lead busy lives which is why we don't expect to keep up with every bit of tech news that comes their way, which also means that when Apple announced their new iPhones yesterday, not everyone might have heard of it. Jimmy Kimmel then decided to capitalize on this by going out onto the streets armed with an iPad mini, and convinced passerbys that the iPad mini was indeed the new iPhone 5S. Of course the footage has been edited to show those who actually fell for the trick, but it is pretty funny either way.
Some were amazed by the iPad mini's graphics (even though it is almost a year old and sort of based on the iPad 2), while other claimed it felt sleek, with one woman even describing her experience with the tablet as "intense". They even had people put the tablet up to their ears to pretend that it was a device, and in one case they even had a girl lick the tablet because they had convinced her there was a new "click it and lick it" feature! If you have a few minutes to spare and want to get a good laugh, you should definitely check the video out.
Filed in iPad mini and iPhone 5S.
. Read more aboutKey Specs | iPhone 5s |
Status | Released |
Display Diagonal | 4" (10.16 cm) |
Processor/Soc Name | A7 |
Street Price (Approx) | ~ $230 Search low iPhone 5s price (Amazon) |
Max. Total Storage Capacity | 64 GB |
Megapixels | 8 Megapixel |
Battery Capacity (mAh) | 1560 mAh |
Complete product data | Apple iPhone 5s Full specs and details |


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Product Details
Infused with a hint of linen - and done in our structured stretch that smoothes and improves in all the right places (in other words: your go-to for superbly sleek) - our pencil pants are straight through the hip and thigh with a slight taper at the ankle. Our curvy fit – your perfect fit if your waist is smaller, but your hips are curvier. Zip fly with hook-and-bar closure. Coin pocket beneath waistband. Slash pockets. Back welt pockets. 26" inseam.


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A staple side dish at my summer cookouts is baked beans. I have a traditional recipe that my family loves, but lately I've been trying to switch things up a bit. I think these baked bean recipes may be just what I'm looking for.
Every parent knows, it can be hard to please the taste buds of everyone at the table. But, it seems like Cindy Ferguson does just that with her Spicy Apple Baked Beans.
Drivers on Craig Farm Road in Lancaster County may have gotten a bit distracted on Saturday, July 12, by the row of shiny Mercedes-Benz automobiles parked neatly in front of Kilburnie, the Inn at Craig Farm.
Sherry Archie
For The Lancaster News
The Haires built their home in 1970. Many of the original boxwoods and hollies kept neatly trimmed continue to thrive in the yard – a direct result of Judy's green thumb.
"Growing plants has always been easy for me," Judy said. "Many times I have just stuck a small cutting from a plant in the ground and it really takes off."
In another realm, I was a ball of fire, always full of energy.
Why, I took on all kinds of projects and tasks of all sorts and sizes around our Charlotte Road Camelot.
Now, I get up in the morning with the best intentions of getting our yard in better shape.
No, I don't mean that blue ribbon, Yard-of-the-Month frenzy.
While I enjoy lookin' at the pictures, once you win that distinction, you are under pressure and the lawn is under neighborhood microscope.
Kayland Hagwood
Special to The Lancaster News
Jimmy Wood knows what he loves about sailing.
"The sound of the waves, the feel of the wind and the smile on my wife's face."
And Wood – the acting commodore of Lake Wateree Sail Club – wants other people to experience those things and understand why the Lake Wateree Sail Club is a great place to share experiences.
Barbara Witte
Special to The
Lancaster News
When I learned about the Southwest Florida Honor Flight, I quickly contacted Don Vecoli, founder and organizer.
He and his staff organize the trips for World War II veterans and volunteers to visit the World War II memorial in Washington, D.C., two or three times per year.
Katie West
USC School of Journalism
Perhaps nowhere in the country more than in South Carolina does the word evoke a sense of history as rich as the smell of meat in the smoker.
A few years ago, when I did some frequent work-related traveling between Springs' Customer Service Center and their New York office, several of those "real city boys" used to chide me about one of my neighborly tendencies.
For some strange, inexplicable reason, they perceived my inclination of nodding and speaking to people on the street as a "bad habit."
Folks in midtown New York City, they said, never make eye contact with total strangers.
If you did, you were asking for trouble.
More than 200 people came to the first Tribute to the Golden Legacy event at Mt. Zion AME Zion Church on Sunday, May 4.
The purpose of the night – honor those who worked at Barr Street before it closed in 1970, said secretary of the BSHS Foundation, Dr. Charmaine Stradford.
Kaisha Young
One girl is popular and comes from an affluent family. One girl is reserved and comes from a middle class family.
Both give no indications that anything's wrong, even though they are both harboring heinous secrets.
Both are victims of teen dating violence.
School district youth/peer counselors Deborah Boulware and Sarah Woodring know this tale all too well after hearing it time and time again.
From release
Nature lovers can become certified S.C. Master Naturalists and join a regional corps of citizen scientists by attending a weekly environmental training course beginning in March at the Anne Springs Close Greenway in Fort Mill.
The Catawba Master Naturalist Program teaches participants how to explore the world around them, identify plants and animals, and better understand ecological concepts they can apply through volunteering in their communities.
Lancaster NAACP release
The fellowship hall at Mount Zion AME Zion Church overflowed with attendees of all ages at the first Town Hall Meeting sponsored by the Lancaster Branch of the NAACP on Dec. 12.
Nearly one hundred people met to present their views on the subject "Crime Watch: Saving Our Youth."
Sean Creeden
It's a cool fall morning in October, and once again streets are closed across South Carolina as runners race another 5K.
These runners rise with the sun to run in one of the many races available on any given weekend. They run to exercise, lose weight and even make friends.
With the holidays and the fun family times along with delicious dinners and deserts that we are destined to eat, I'm going to give you a few extra treats on how to keep your abs and waist line in tip top shape and still enjoy eating your favorite foods.
Whether dashing to visit family or just getting away for a leisurely trip, families spend the winter holidays away from home for different reasons.
The "Three House Run"
Christmas travels begin at 5 a.m. Dec. 24, for the Camp family, who set out on their annual holiday journey to Warner Robins, Ga.
Nov. 2, 2013
There's got to be at least 40 volunteers here.
Some crouching, hammers in hand. The hollow sound of tools banging against the wood echoes. The noise slicing through the autumn air.
Finally, the progress is visible – it's tangible.
Eighty-four-year-old James Hagins is a retired Lancaster resident. He spends his days taking it easy, napping in his recliner when he feels like it. When he lost his wife of 60 years, Peggy, in September of 2012, he found an unusual outlet for his grief – quilting.
"My mother quilted, and with eight of us children, she definitely had help when she needed it," he said. "I didn't mind helping her, and sometimes I was the only one she would let help, because I did things the way that suited her."
If you can't make it the mountains to choose and cut your Christmas tree there's no need to worry – Lancaster County has it covered.
Papa John's Christmas Tree Farm, located at 6980 Flat Creek Road in Kershaw, offers six different varieties of trees customers can choose and cut, including Blue Ice, Carolina Sapphire, Eastern Red Cedar, Leyland Cypress, Virginia Pine and White Pine.
Decking the halls for the holidays is a beloved tradition for many families. A home's exterior festooned with lights help create a festive holiday mood, while stockings hung by the chimney and a Christmas tree in the living room bring that holiday cheer inside.
Though the holiday season is a festive time of year, it can quickly turn tragic if safety is not emphasized when decorating a home. When decorating this holiday season, be sure to employ the following precautions so your holiday season is festive, decorative and safe:
On Thanksgiving Day, Alex Sims turned 100.
The Van Wyck man credits his long life to hard, but satisfying work on his 225-acre farm at the corner of U.S. 521 and S.C. 5. He bought the land after two stints in the U.S. military.
"It doesn't matter how much money you make if you like what you're doing. Keep it up," said Sims, who cut his own winter firewood with an axe until he was 97. "You have to love your life."


text: A chatbot's hilariously nonsensical script has been turned into a short filmGeorge Dvorsky2/08/13 9:30amFiled to: This is awesomeFuturismchatbotsCleverbotshort filmsVideo36EditPromoteShare to KinjaToggle Conversation toolsGo to permalink A few weeks ago we predicted that the day is fast approaching when a machine will be able to write a scifi novel or a short story. Well, despite the short film presented here, we're still sticking to that prognostication — though it's now painfully clear that we're going to have to wait a while before an AI can produce something that's actually watchable. Check out the video to see what we mean. Called "Do You Love Me," this unintentionally surreal romantic comedy was created by director Chris R. Wilson. He pieced the script together by engaging Cleverbot in a conversation — clearly his first mistake. The resulting dialogue was incorporated into the short film, resulting in a story that makes about as much sense as most Hollywood scripts these days.Reply36 repliesLeave a reply


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Chris Pine busted for DUI in New Zealand!
Comments 0
Posted by: Jocelyn
Chris Pine has been arrested for DUI after failing a sobriety test, and blowing a .08.
Chris was partying at a bar in New Zealand with some fellow actors and his girlfriend, beauty queen Iris Bjork Johannesdottir, when he decided to leave after some drinks. He drove through a checkpoint, and police then made him stop. He blew a .08, the minimum for being legally drunk.
The incident happened on March 1, and he must appear in court on Monday. According to sources, Chris was very polite and "easy to deal with."


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The piece, described by Janney as "an abstraction of Georgia in color and sound", features 32 CHAUVET® Intimidatorâ"¢ Scan LED 300 scanners, 68 horizontal panes of colored glass—stacked in 17 sections with four panes in each section—along a 160-foot hallway. As the light from the recessed fixtures in the ceiling passes over the glass, it reflects and refracts creating a continuously changing pattern of color on the wall.
Janney, who is a trained architect and jazz musician, composed a score of environmental accents—indigenous sounds of natural Georgia environments—that accompany this "light ballet." Additionally, the hallway features a series of interactive "touch panels" that are activated by a passerby triggering a soft tone. The light and sound work together creating an immersive experience for travelers making them part of the artwork.
"After extensive research for 'Light Waves: Atlanta'," said Janney. "The CHAUVET® Intimidatorâ"¢ Scan LED 300, as a single-source LED with a hard edge that penetrates through four panes of glass, was hands-down the best fixture on the market."
"LIGHT WAVES: ATLANTA" Atlanta International Airport
©2012 PhenomenArts, Inc. C. Janney, Artistic Director
Photo: M Jensen
Sponsored Introduction Continue on to (or wait seconds) ×


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Results 11 to 12 of 12
Not great, with the current administration and senate. But, we're not talking about Right to Work, we're talking about the Sherman Act exemptions that were put into law with the Clayton Act. Unions that want to try to organize should be bound by the same laws as the companies that they are trying to extort money from. I have no problem with a union trying to talk people into joining. I have a huge problem with that union having a monopoly on labor and using violence to enforce it.
Sic Hacer Pace, Para Bellum.
Before you can do things for people, you must be the kind of man who can get things done. But to get things done, you must love the doing, not the people!
« Previous Thread | Next Thread » |


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What's Happening The Boise State University men's golf team will travel to Layton, Utah, to compete in the Purple and Red Invitational. The tournament, co-hosted by Weber State University and the University of Utah, will be held Sept. 18-19 at the Valley View Golf Course. The Field Boise State will be joined at the event by 15 other schools. The Players Matt Hastings leads a young Broncos' golf team which features two junior varsity transfers and six freshmen. Last season at the Purple and Red Invitational Hastings shot a 214 (-2) to finish tied for 10th. He finished in the top 10 in three of nine events last season, as well as placing in the top 25 in six of nine events. Also competing for Boise State are junior Troy Merritt and freshmen Robbie Richards, Robbie Heithecker and Shawn Tonkin. Merritt a native of Fridley. Minn., hails from the junior college ranks where he earned Northern Sun Intercollegiate Conference MVP and Central Region MVP accolades. Merritt also garnered GCAA Division II PING All-America honors. Richards comes to Boise State from Tea Gardens, Australia, where he won the South West Rocks and Bathurst Junior Masters Championship. Heithecker, (Nampa, Idaho) led Vallivue High School to three district championships and four trips to the State championships during his tenure. He was also a member of the all-state team three times. Tonkin of Mercer Island, Wash., was a WJGA State Champion in 2004 and a two time IJGT All-American. --broncosports.com-- |
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Phone: (208) 426-4737
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Email: firstname.lastname@example.com


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Talk:Elvis Impostors
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The name of this page seems...awkward. Shouldn't it be Elvis Impersonators or something of the like? Jackbel (talk) 21:15, April 28, 2014 (UTC)
Aye, I agree. Buchodude (talk) 04:17, May 12, 2014 (UTC)
Might be, I named it like this because some GTA2 files reveal them like this AFAIK. Jeansowaty 16:15, July 21, 2014 (UTC)Jeansowaty


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Notez qu'elle n'a pas dit "sioniste". Mais on sait de toute façon que cela
ne fait aucune différence pour les médias et les organisations juives.
BBC Washington correspondent Katty Kay
BBC correspondent has been criticised by the Board of Deputies for
using the term "Jewish lobby" in discussing the American election.
Washington correspondent Katty Kay, in a recent Twitter question and
answer session, had been asked why both American President Obama and
Republican challenger Mitt Romney were "so defensive" when questioned
about their commitment to Israel.
She replied that the US "sees Israel as a key ally in Middle East —
but no one running for president wants to alienate the power and money
of the Jewish lobby".
Board chief executive Jon Benjamin said that the reporter's "loose
use of language really has to be seen in a context where support for
America's key ally in the Middle East is cynically questioned — and the
motives of Israel's supporters are seen as suspect".
Successive US governments, he said, "have recognised the value of
this strategic relationship to the national interest, and it is
unfortunate that a BBC journalist falls into the trap laid by Israel's
enemies and conspiracy theorists of reducing support for Israel to
parlance of Jewish money and power".
A spokesman for the Anti-Defamation League in the United States said
that Ms Kay's remark "reveals a surprising lack of understanding of the
broad support of the American people for a strong US-Israel
relationship, which is the underpinning of US foreign policy toward
"And, at worst, the remark suggests she accepts the mythic notion of a
powerful Jewish cabal able to control how US foreign policy toward
Israel is determined."
He added: "Of course, this just may be another example of how
complexity and context are sacrificed for the sake of an answer limited
to 140 characters."
A BBC spokesman said that the correspondent's "primary point in
responding was that the US regards Israel as a key ally in the Middle
East and also recognises the importance and influence of this
relationship on the voting".
Les massmédias antisémites? Le Washington Post rapporte que le virus Flame serait, comme Stuxnet, une cyber-arme us-israélienne contre l'Iran
Maîtres du monde, maîtres de l'humour: Netanyahou accuse le New York Times et Haaretz de donner le ton de la campagne anti-Israël à travers le monde
Un autre grand comique, propriétaire et éditeur d'un journal juif américain, soutient qu'il ne prônait pas vraiment l'assassinat d'Obama
Une comique juive au parlement israélien: je ne voulais pas heurter la mémoire de la Shoah en dénonçant le cancer de l'immigration africaine en Israël


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Celebrate the health of women in your life with easy-to-make pink cupcakes with supportive messages.
If you have only one pan and a recipe calls for more cupcakes than your pan will make, cover and refrigerate the rest of the batter while baking the first batch. Cool the pan about 15 minutes, then bake the rest of the batter, adding 1 to 2 minutes to the bake time.
You can also use a decorating bag with flat tip with 1/4-inch wide opening (#44) to write messages on the frosted cupcakes.


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The service levels are as follows:
Data Sheet Fujitsu Support Pack Hardware
English, German
ProActive Support - Attachment to the Data Sheet Support Pack
English, German
Data Sheet Fujitsu ServiceContract Hardware
English, German
Data Sheet FUJITSU ServiceContract for Oracle SPARC Enterprise Server
English, German
In case a faulty hard disk or SSD cannot be repaired and needs to be replaced, the exchanged device usually has to be returned to the manufacturer. But what happens with the company-confidential data stored on the faulty disk/SSD?
With the HDD retention option, the exchanged device remains the customer's property. This ensures that company-confidential data won't leave a company.
Regarding the availability of the HDD retention option see Product Support Services at a Glance
Share this page |


text:
Ohio Teen's Sentencing Delayed In Craigslist Plot
AKRON, Ohio
Sentencing has been delayed for an Ohio teenager convicted in a plot to lure men desperate for work with phony Craigslist job offers.
The judge said sentencing will be held Friday but did not explain the reason for the delay. All parties in the case are under a gag order.
The mother of 17-year-old Brogan Rafferty says the delay is "probably" related to a possible deal for leniency in return for her son's testimony against the alleged triggerman, Richard Beasley.
Three men were killed and a fourth victim was shot but survived.
The jury rejected the defense claim that Rafferty feared for his life if he didn't cooperate with Beasley.
The 53-year-old Beasley has pleaded not guilty and will be tried in January.
©2017 by The Associated Press. All rights reserved. This material may not be published, broadcast, rewritten or redistributed.


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Page 2 of 12
Tom: Tuesday Dinner
Gourmands with a reservation here can expect an intimate meal planned and prepared by the host of Bravo's Top Chef and the mind behind Manhattan's "Craft" restaurants. On opening night, last month, that included grilled stuffed squid in a squid-ink risotto made with cocoa nibs. The restaurant will be open only two Tuesdays a month and will serve 28 diners at a time. Depending on the ingredients used, the prix-fixe menu is expected to cost $250.
For more information, visit www.tomtuesdaydinner.com/home.


text:
Alternative Titles:
"Il giorno della civetta", "The Day of the Owl"
Learn about this topic in these articles:
discussed in biography
...writing, Sciascia did not discover his favourite vehicle, the mystery novel, until the publication in 1961 of
Il giorno della civetta ("The Day of the Owl," first Eng. trans.
Mafia Vendetta), a study of the Mafia. Other mystery novels followed, among them
A ciascuno il suo (1966;
A Man's Blessing),
Il contesto (1971;
Equal Danger), and...
Italian literature
...and past he displays with concerned and scholarly insight, with two of his better-known books—in the format of thrillers—covering the sinister operations of the local Mafia (
Il giorno della civetta [1963;
The Day of the Owl] and
A ciascuno il suo [1966; "To Each His Own"; Eng. trans.
A Man's Blessing]). After a...


text:
Some of the prizes are:
- A Vegetable Grilling Rack from Pampered Chef
- $25 Gift Basket Sponsored by Kristine's Shower
- A Sock Monkey Hat & An Owl Hat
- My Memories Suite 2 Digital Scrapbooking Software
- $50 Gift Code to "Just Eyewear"
- Signed Book, "Dawn of Saudi"
- "My Hare Line" book series (4 children's books)
- A Cody Simpson Doll
- A Full Bag of Books!
You can read my Sponsor Spotlight post HERE
Only (1)one winner will be chosen via www.rafflecopter.com.
Open to US ONLY!
a Rafflecopter giveaway


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New subscription
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Amyr Fixation
Active within 1252 Days
I am from Williamsport, PA and I've been a Club Horse member for 3 years, 9 months and 11 days
Nicknames: fixation, buddy, bubby and stud muffin
Age: 16 years old
Gender: Stallion
Breed: Arabian
Height: 14.3 hands
Color: dapple grey
Type of Riding: he will drive a cart soon
My Horse's Achievements: he has bred some beautiful foals, flirts with the mares, and will soon learn how to drive
My Horse's Favorite Treat: my homemade treats with peppermints in it
My Horse's Favorite Things To Do: flirt with the mares and run around in the pasture
Pet Peeves: being away from the mares and really loud noises.
My Horse's motto: show me the mares!
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we bought him at a huge horse sale.
I've had 974 friends visit me.
I'm the 41,754th member on HorseChannel.com.
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Your skill will accomplish what the force of many cannot |
PerlMonks |
Re: Use variable as a module during runtime.by NetWallah (Abbot) |
on Oct 21, 2012 at 02:36 UTC ( #1000166=note: print w/replies, xml ) | Need Help?? |
Yes - it is certainly possible. Why don't you try it, and let us know what problems you encounter. "By three methods we may learn wisdom: First, by reflection, which is noblest; Second, by imitation, which is easiest; and third by experience, which is the bitterest." -Confucius
In Section
Seekers of Perl Wisdom


text:
Story highlights
- New York University lost years of research in cancer and neuroscience
- Storm knocked out power to freezers, water flooded animal facilities
- NYU awaiting guidance on how much funding they can apply for and receive
It's been three months since Hurricane Sandy barreled along the East Coast, plunging the majority of Manhattan and surrounding boroughs into darkness, and displacing hundreds of people from their homes.
As neighborhoods continue to rebuild, and in honor of the three-month anniversary, President Barack Obama recently signed the much-anticipated Sandy Relief Bill for $50.5 billion.
One group awaiting some of that recovery funding are scientists and researchers from New York University, who lost years of research in cancer and neuroscience when the storm knocked out the power supporting their freezers, and water flooded their animal facilities, drowning their mice.
On the night the storm surge hit the city, the power outage at the NYU Langone Medical Center became a closely followed emergency. A fuel oil storage caused the hospital's back-up generators to malfunction, and about 300 patients were evacuated to neighboring hospitals in the city.
In the same outage, NYU's scientific animal research centers, including the Smilow Research Center, one of the largest animal research facilities housing lab mice and specimens critical to heart disease, cancer and brain research, were severely damaged.
"It is not very different from someone losing their entire home. For scientists, their research is their lifeline," says Dr. Dafni Bar-Sagi, senior vice president and vice dean for science and chief scientific officer for NYU. "For someone who started three to four years ago, and just got to a point to launch their research program, it's time to rewind and start from fresh."
In the 36 hours leading up to the storm, a team of NYU Langone staff members led by Jennifer Pullium, director of the division of laboratory animal resources at the NYU Langone Medical Center, prepared the lab animals for the incoming storm by stockpiling food and bedding and moving cages to higher shelves.
It should've been enough to keep the valuable lab mice alive for up to 10 days if the scientists couldn't reach them before then.
The animals were kept in the basement, a decision that's been questioned, but the university insists it is a standard industry practice. Study animals must be kept in controlled cycles of light and dark -- something that's easiest in the absence of natural light. Most of the equipment used to maintain the animals is typically too heavy for upper floors and the animals are also kept in near-sterile "super clean" conditions, meaning moving them without an urgent need would compromise their health.
Should they have been moved? Perhaps. But the researchers insist the storm was an unprecedented event for NYU, and equally unexpected.
The medical center's emergency power system was supposed to withstand a flood surge of approximately 12 feet, but with estimates of the actual surge at two feet higher, the hospital quickly plunged into darkness and staff members securing the animals scattered.
"It was a matter of minutes until we had to get our staff out for their own safety," says Pullium. "It happened so fast."
Bar-Sagi says she realized the worst was possible when the power in her own apartment quickly sputtered out. After a sleepless night, she walked to the hospital at 4 a.m. to assess the damage. Communication lines were down, but NYU researchers throughout the city hurried to the scene to save whatever biological specimens they could from their failing fridges.
For the following four days, Bar-Sagi orchestrated research evacuation efforts and held meetings in stairwells and empty offices to calm concerns of desperate researchers unable to get to their animals.
After the storm
A week after the storm, when the flooding had subsided, workers used crowbars to break into the basement at Smilow, and discovered 600 cages on the upper shelves still housed living lab mice. They cut holes through the ceiling and lifted the cages through, four at a time.
The discovery was a silver lining, but considering a total of 7,660 cages of mice and 22 cages of rats were trapped in total, the loss was still overwhelming for many.
Months after the storm, NYU researchers are still working in makeshift labs throughout New York. Some have set up shop in their colleagues' labs on the NYU campus, and others are working at neighboring research institutions like Rockefeller University, an unconventional collaboration given the competitive nature of science community, similar to two rival sports teams sharing training time.
The researchers hardest hit are those who rely on animals for the better part of their experiments, such as Dr. Gordon Fishell, the associate director of the NYU Neuroscience Institute, whose work focuses on connecting brain function to disease. Fishell's lab chemicals survived for the most part, but he lost most of his mouse population that was critical to his investigation of diseases like schizophrenia, bipolar disorder and epilepsy.
"(The mice) are our partners in discovery. We care a lot about them," says Fishell.
Mice make ideal models for scientific research of human diseases, since they are easy to manipulate genetically. But when scientists modify the mice with specific genetic tweaks, they are difficult to replace.
Fortunately, Fishell, like many other researchers, shared some of his strains with other research institutions that are willing to provide him with mice for breeding, making the task slightly less daunting.
Still, before Sandy hit, Fishell had approximately 800 different strains of mice, of which about 20 were uniquely bred by his team, each with several layers of modifications that he was tracking over several generations.
"These mice cost quite a bit. Anywhere from on the low-end of $20,000 (to) the high end (of) well over $100,000 to make," says Fishell.
And that's not accounting for the time that he and his lab members devoted to breeding the animals. It takes eight weeks for male mice to mature sufficiently to reproduce, six weeks for female mice, and gestation lasts about 19 days. It takes even longer depending on how many generations are needed to pass along the modifications.
"It takes about a year to produce them if everything is ideal and perfect, and usually everything isn't," says Fishell.
"We are in an incredibly vigorous and exciting time for brain research. A year of lost time is a year of lost time," says Fishell. "Maybe you're ahead of people, and suddenly you've lost that year and nothing stays still."
Similarly, Mary Helen Barcellos-Hoff, a professor of radiation oncology and cell biology at NYU and her team lost mouse populations involved in studies of how radiation exposure increases cancer risk as well as how radiation can be targeted to treat tumors. Her group lost their mice as well as their radiation equipment, including a brand new, half million-dollar machine that took two years to obtain.
When the power went out, Barcellos-Hoff's researchers spent hours climbing up and down eight flights of stairs, trying to save specimens stored in thawing freezers.
"They trudged in the dark, carrying our precious samples that we stored from experiments we have already completed," says Barcellos-Hoff. "We work on those for years, and those are the most precious things in our laboratory. We can always replace equipment, we can always replace reagents, we can even replace mice, but replacing an experiment that took you two years to complete is really tedious."
Acting quickly, Barcellos-Hoff's team was able to rev up some of their ongoing studies to meet deadlines, but were forced to terminate others. Even though some of their mice survived the storm, Barcellos-Hoff says they could never account for the effect that the week and a half the animals spent in the dark might have had on the results.
Awaiting funding
Despite the challenges, the researchers are optimistic that they will be able to resume most of their work. Their slow-moving recovery is frustrating, but support from the academic community has provided hope. Within four days, Fishell received 100 emails from competing scientists offering their services and even volunteering to breed mice for him.
The National Institutes of Health Director Francis Collins and NIH Deputy Director for Extramural Research Sally Rockey also visited NYU to survey the wreckage and show solidarity.
"I can tell you the damage is truly appalling," Collins wrote on his blog. "Some of the labs are unusable because the infrastructure has been essentially obliterated."
The NIH promised to help ease the transition by altering submission deadlines for grants, negotiating new goals for ongoing projects and extending training hours for new researchers.
The greatest relief will likely come from the funding the NIH allocates toward NYU. Currently, the Department of Health and Human Services is sorting out how much of the $195 million Emergency Fund from the Sandy Relief Bill will go to HHS agencies, like the NIH. After that, NYU will await guidance on how much funding they can apply for and hopefully receive.
In the meantime, all they can do is work with what they have and wait. But the researchers remain patient, because they don't have another choice.
"It takes a certain level of courage to do science," says Fishell. "These people are betting their entire careers that they can do something no one has done before, get a result they can interpret, and discover something. I'd say [my researchers] gave themselves about 24 hours to sit there and think, 'Oh my God. How can I get by this?' and then they got back on, and have not looked back."
This story was originally published on TIME.com


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SEATTLE -- No one in the Oakland clubhouse can offer a plausible explanation for the Athletics' dominance of Seattle this season.
And when it's Barry Zito on the mound against the Mariners, victory is almost assured.
Zito overmatched Seattle yet again, and A's won their 10th straight over the Mariners with a 5-2 victory on Friday night.
With the teams separated by just 3½ games in the AL West entering Friday, Zito pitched seven innings, allowing one run and seven hits, as the first-place A's won for the fifth time in six games.
It was a giant dud for the Mariners, starting what many consider the most important series for the franchise since 2003, the last time they were in a pennant chase.
"I can't explain it at all. I look at their players and they're a good team," Oakland manager Ken Macha said. "It's tough to put your finger on it."
After dropping its first game to Seattle on April 6, Oakland has won every matchup since, including two three-game sweeps in Oakland. The A's were 12-6 against Seattle last season.
Zito's almost equally dominant. The left-hander improved to 12-2 in 22 career starts against Seattle and lowered his ERA against the Mariners to 3.49, even though his scoreless innings streak against them ended at 21.
Zito (12-7) wasn't sharp early, but pitched his way out of trouble with some key double plays, as Seattle left six runners on base over the first four innings.
In the fifth, Zito got a huge momentum boost from a pitch that slipped. Jose Lopez led off with a single. Seattle tried to hit-and-run with Adrian Beltre at the plate. Zito threw a curveball that "squirted" out of his hand and came to the plate very high. Beltre swung and missed and Lopez was easily thrown out trying to steal.
Zito then retired the last eight batters he faced.
"That was huge. That was a momentum shift," Zito said. "Something like that happens and it sparks you. We have new life now and you have to roll with it."
In two previous starts against Seattle this season, Zito didn't allow a run, and combined with three relievers to one-hit the Mariners on April 8. The former AL Cy Young winner won for the fourth time since the All-Star break.
Zito got all the offense he needed from Marco Scutaro, who had three hits, including his fourth homer of the season with two outs in the eighth off reliever Julio Mateo.
Scutaro, filling in at shortstop for the injured Bobby Crosby, also hit an RBI double in the fourth and singled in the sixth.
"I've been playing lately a lot, and seeing a lot of pitches and feeling better," Scutaro said. "When you score some runs for Barry, it's pretty much a win."
Seattle starter Jarrod Washburn (5-11) battled through control problems to keep the Mariners close, but still lost for the fourth time in his last five decisions and missed an opportunity to win consecutive games for the first time with Seattle.
Washburn walked three, hit two batters and allowed four runs in seven innings.
"Ten straight is a little ridiculous. It's one of those things you can't explain," Washburn said. "We haven't played terrible or played scared against them, they have just played better than us."
The A's took the lead for good in the fourth. Eric Chavez and Bobby Kielty led off with singles and Scutaro doubled over the head of left fielder Raul Ibanez to score Chavez.
Mark Ellis was hit in the back by Washburn's next pitch to reload the bases. Jason Kendall then grounded into a double play, but Kielty scored for a 3-1 Oakland lead.
Oakland added a run in the seventh, when Kendall scored on Frank Thomas' two-out, two-strike single to left. Kendall beat Ibanez's throw home. Jay Payton doubled and scored on Ellis' two-out single in the second for the A's first run.
Zito's scoreless streak against Seattle ended when Ibanez, hitting .378 with two outs and runners in scoring position, lined a single to left scoring Willie Bloomquist from third. Richie Sexson hit his 24th homer in the ninth off Justin Duchscherer.
"Do we want to beat Oakland? You bet," Seattle manager Mike Hargrove said. "September is a long way off ... and we have to pay attention to tomorrow."
Zito has not lost to Seattle since July 23, 2003. ... Seattle's last run off Zito was a homer by Ichiro Suzuki to lead off the game on June 28, 2005. ... Oakland placed Crosby on the 15-day DL with a lower back strain. IF D'Angelo Jimenez was called up from Triple-A Sacramento to take Crosby's roster spot. ... Oakland's Mark Kotsay extended his hitting streak to 11 games with a single in the first inning.


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World congress to discuss energy futureThe future prospects of the oil & gas, coal, nuclear, and renewables sectors will be discussed by leading figures in the energy sector at the 2013 World Energy Congress in South Korea in October. More… |
Iran discovers new oil, gas fieldIran's oil minister announced on Saturday the discoveries of an oil field and a gas field, estimating the total value of their reserves at $85 billion, a semi-official news agency reported. Massoud Mirkazemi said the newly-discovered o More… |
Iran sees $7bn deals with Europe, IndiaIran expects to finalise two energy contracts totalling $7 billion with an unnamed European firm and with India's state-run Oil and Natural Gas Corp respectively, state broadcaster IRIB said on Tuesday. Citing Mahmoud Zirakchian-zadeh, man More… |
Saudi shura urges long-term gas strategySaudi Arabia's advisory Shura Council has urged the oil ministry to come up with a long-term strategy for domestic gas supplies and demanded greater transparency in allocation of the fuel. Demand for gas in the kingdom for power and in More… |
Technology to help boost oil productionInvestments in technologies are set to increase oil production and reserves in the Middle East, according to an expert. The Middle East oil & gas producers could substantially boost production and reserves through investment in technol More… |


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Arizona State has scheduled a Thursday news conference to discuss a possible return to Camp Tontozona, a mountain property near Payson that served as a preseason training site for the football team for 48 years. | Camp Tontozona
Vice President of Athletics Steve Patterson and football coach Todd Graham are expected to attend the news conference. A school spokesman said they would not announce a definite return to Tontozona, today known as Retreat at Tontozona. Instead, they likely will discuss what is needed for the Sun Devils to return.
Since his hire in December, Graham, who understands the importance of tradition, has said he is open to returning to Tontozona. At one point he said that nearly everyone he met asked him to consider returning to the location. (Graham also pointed out that the last time the Sun Devils trained there - 2007 - they won 10 games.)
To make it worthwhile, the coach told The Republic that a 4-to-6 day stay would be ideal. In February, Patterson, Graham and other ASU officials visited Tontozona, trying to get a grasp of the upgrades and changes required for a possible return.
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August 23, 1978 - A photographer captures an ASU football practice on a film camera at Camp Tontozona.
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One-Minute Essay Response (Student 2) - Section 3: Lend Me Your Line: Responding to and Exchanging Lines
What's Your Line? Close Reading of Selected Lines from the Romantic, Victorian, and Modern Periods
Lesson 2 of 9
Objective: SWBAT use reader response techniques to connect to poems from the Romantic, Victorian, and Modern periods of British literature.
In the first lesson, students composed poems about themselves by completing a copy change of "Where I'm From" by George Lyon.
Today, in Lesson 2 of a two-week poetry unit, students interact with British Poetry from the Romantic, Victorian, and Modern literary periods. To accomplish this, students
- Participate in a line tossing activity,
- Create two-person poetry skits with their lines,
- Pick a poem from the Romantic, Victorian, or Modern era by picking a line from the line tossing activity.
Casting Lines of Poetry
Begin the lesson w/ a line-tossing activity. Poetry Line Tossing.mp4 explains how to prepare the lines for the activity.
To begin the lesson, distribute lines from the poems students will be working with to students. Line tossing lines are from poems from the Romantic, Victorian, and Modern eras of British poetry, and with few exceptions, they are poems in our textbook, although students don't yet know this.
I tell students they will read their lines and then mill around the room sharing the lines with their classmates. I also participate in the activity with students so that I can hear how they read, answer questions for students, and model how to read and interpret poetry.
Students get out of their seats and begin sharing their lines until they have shared with most of their classmates.
After line tossing, students use the Poetry Line One-Minute Essay prompt as a way to respond to their lines, which we see in One-Minute Essay Response (Student 1).
Resources (4)
After the initial line tossing, I ask students to exchange lines with someone sitting close to them.
They exchange lines, and then we repeat the line tossing activity, only this time for a shorter period of time.
Once again, students use the sentence starters to respond to their lines: One-Minute Essay Sentence Starters. One-Minute Essay Response (Student 2) and One-Minute Essay Response (Student 3) show student responses to their lines.
Next, I ask students to share some of their responses to their lines, and we begin to discuss whether or not students like their lines.
Resources (3)
Poetry is all about the way writers play with words. To assist students in their understanding of this play, we turn our attention to creating poetry line skits. I give the students instructions:
You are to pair up w/ another student to create a skit from your lines. You may divide the lines in any way you wish, and you may exchange lines. You may not, however, change the words in any way. That is, you may not use a synonym for a word or add new words. You may use props and/or costumes if you so desire. I will give you five minutes to create and practice your skit. Remember, you are creating a skit, which implies moving your body and using your voice to convey meaning in the lines. Most importantly, you need to have fun!
I ask for a volunteer and demonstrate how to change and split the lines and how to add movement to the lines so that they become a skit.
I set the timer and mill among the students so that I can respond to their questions and reassure them that it's okay if they're a little nonsensical in their performances.
Next, we present our skits for one another. As the images show, some of the pairs really got into the performance aspect of the activity. Poetry Pair Skit (1) and Poetry Pair Skit (2) show students in poetry poses as they perform their skits.
I played around with these two images using an app on my iPad Mini and created the sepia-infused montage Poetry Line Skits.
Resources (3)
At the end of the lesson, students decide whether or not to keep their lines or exchange them for new ones. I tell students that the lines are from poems they will work with for the remainder of the unit, so it's important that they like their lines.
Most decide to keep the lines they have, and a few moan because they want their original lines back. A couple of students decide to trade, so I allow them to pick a new line from those remaining.
Next, I write the number of each student's line down on the original document. This will allow me to identify the poem after class and distribute the complete poem to each student in the next class.
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- UNIT 1: In the Beginning: The First Three Days of School
- UNIT 2: Raising Readers: Getting Students to Read in and out of the Classroom
- UNIT 3: Because He Hears a Different Drummer:Various Approaches for Comparing Genres and Analyzing Texts
- UNIT 4: Such Stuff as Dreams are Made On: Innovative Approaches to Teaching Narration and Description
- UNIT 5: The Readiness Is All: Engaging Your Students in Persuasive Writing
- UNIT 6: We Need a Hero: The Anglo-Saxon Epic "Beowulf"
- UNIT 7: Take a Little Trip: The Middle Ages and Chaucer
- UNIT 8: Oh, Horror! Horror! Horror! "The Tragedy of Macbeth"
- UNIT 9: "The Taming of the Shrew" by William Shakespeare: Unmasking a Troubling Text
- UNIT 10: Romantic, Victorian, and Modern British Poetry
- UNIT 11: Making Discoveries: Research-Based Writing
- UNIT 12: What Makes a Monster?: "Mary Shelley's Frankenstein: The Modern Prometheus"
- UNIT 13: Reading and the Empathetic Imagination: Teaching in Literature Circles
- UNIT 14: Endings Leading to New Beginnings: The Last Three Days of School
- LESSON 1: "Where I'm From": Introducing Students to Poetry of Place with Copy Change
- LESSON 2: What's Your Line? Close Reading of Selected Lines from the Romantic, Victorian, and Modern Periods
- LESSON 3: "Find Someone and Ask..." Poetry Discussion
- LESSON 4: "Hey, Ya. Shake It Like a Polaroid Picture": Transforming Close Reading with Image Annotation of Poems
- LESSON 5: TPCASTT Poetry: A Close Reading Strategy
- LESSON 6: Is it Romantic, Victorian, or Modern? Putting Poems in Their Place
- LESSON 7: Ars Poetica and Illuminated Texts: Responding to Poetry through Artistic Represenation
- LESSON 8: Psst, This Poem Has a Personal Secret for the Reader: Composing the Reader Response Essay
- LESSON 9: A-P-P-L-A-U-S-E: Put Your Hands Up for Illuminated Poetry Presentations


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If you're going for more of an easy, breezy, warm weather look, the Galleon maxi dress will be picture perfect during those summer months. It's something we'd rock everywhere from the boardwalk to a lunch date –the rich purple hue and intricate gold patterns make it incredibly versatile.
As a beach cover up, the Sea Star dress' flowing fabric and 'notice-me' shade will have guys flock to you as you're watching the waves.
And when it comes to pants, the Voyager trouser is airy enough for a warm spring day on the grass. We're feeling nostalgic already!
Read 2012 People's Choice Awards: The Gorgeous, The Fierce, and the… Hmmm
This collection is filled with more than a few must-haves for the Kat Von D gal. But there are also several misses that definitely would not get you Johnny Depp's attention. First up, the Billow could have been a trendy white and grey tunic, but looks more like an oversized plastic bag. Maybe, just maybe, it would look better belted, but the uneven grey coloring on the bottom screams 'I was just swimming in dirty water.' Eek.
Though every lady could use a pair of summer shorts, you might want to avoid the Luna shorts. These acid wash cutoffs should stay in the '80s and out of our closets.
And the Banyan skirt's ruched sides make it a bit too bulky –even for naturally slim women. Do we really want to invest in bottoms that make us look larger? Didn't think so!
Though almost all of the tees and leggings were wearable, we're hoping Kat steps it up a bit in future collections. Despite the bumps, we do recommend investing in one of her gorgeous jackets or dresses. Coupled with Kat's smoky shadows, you'll look sexy all spring long!
Diana Denza is a regular contributor to BettyConfidential.