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Researchers Discover Mutations Linked to Relapse of Childhood Leukemia
Available for logged-in reporters only
Nature Genetics (February 3, 2013)
Finding Emerged from 100 Billion RNA nucleotides in 10 Children with Cancer
Newswise — After an intensive three-year hunt through the genome, medical researchers have pinpointed mutations that leads to drug resistance and relapse in the most common type of childhood cancer—the first time anyone has linked the disease's reemergence to specific genetic anomalies.
The discovery, co-lead by William L. Carroll, MD, director of NYU Langone Medical Center's Cancer Institute, is reported in a study published online February 3, 2013, in Nature Genetics.
"There has been no progress in curing children who relapse, in spite of giving them very high doses of chemotherapy and bone marrow transplants," said Dr. Carroll.
The discovery suggests how scientists may be able to thwart a dangerous form of acute lymphoblastic leukemia, a rapidly progressing blood-borne cancer that strikes about 6,000 people in the United States every year and accounts for more than one in four pediatric cancers. Eventually, such information could help doctors detect the early emergence of chemotherapy-resistant leukemia cells in patients and switch to a different treatment strategy before the disease can fully reassert itself.
In acute lymphoblastic leukemia, abbreviated ALL, the body's bone marrow produces an abnormally large number of lymphocytes, or white blood cells. Improved treatments have increased the overall cure rate to roughly 80 percent. But Dr. Carroll says the prognosis is especially dire for some 20 percent of patients who relapse.
Medical researchers have suspected that the reemergence of disease could be due to drug resistance, but previous efforts had not uncovered any definitive pathway. For the new study, led by Dr. Carroll and graduate student Julia Meyer, researchers at five U.S. institutions spent three years analyzing multiple bone marrow samples from pediatric ALL patients for more clues to the disease's progression.
With the help of the Children's Oncology Group, a multi-institutional clinical trials consortium supported by the National Cancer Institute, the researchers analyzed the entire transcriptome—or the full sequence of RNA —from 10 children with pediatric B lymphoblastic leukemia, the most common subtype of ALL. RNA is an essential intermediary in the cellular process that uses DNA blueprints to assemble specific proteins, thus a leukemia transcriptome gives researchers a view of all active genes within the cancerous cells.
For each patient, the team pieced together a complete sequence of RNA extracted from the bone marrow at three time points: at diagnosis, during remission, and upon relapse some months or years later. All told, the project required the researchers to sequence, or spell out, 100 billion letters of RNA. By comparing the before and after sequences, the team found that each patient had acquired between one and six mutations that changed the genetic code over the course of the disease. In some cases researchers were able to detect these mutations in a very small subset (0.01 percent) of the tissue samples at diagnosis so that these cells likely expanded because their drug resistant properties provided the leukemia cells with a survival advantage.
In all, the team documented 20 relapse-specific mutations—none of which had previously been implicated in ALL recurrences. Intriguingly, two patients harbored a mutation in the same gene, NT5C2, which encodes a protein that normally regulates some building blocks used to construct DNA but also can degrade an important class of drugs called purine analogues used in ALL therapy.
When the researchers fully sequenced the NT5C2 gene in 61 other cases in which pediatric ALL patients had relapsed, they found five more mutations that altered the gene's coding region. Further experiments suggested that these NT5C2 mutations all increased the protein's enzymatic activity, making the cancer cells more resistant to a chemotherapy treatment designed to force the cells to kill themselves. All seven patients with NT5C2 mutations relapsed within three years of the initial diagnosis—an early, particularly hard-to-treat re-emergence likely mediated by the drug resistance.
Armed with the new knowledge, Dr. Carroll says doctors may be better equipped to identify patients likely to relapse. "We plan to test the feasibility of screening patients during therapy using sophisticated sequencing technology to pick up low-level mutations in NT5C2 and other genes indicating that a mutant clone is growing," he says. His team is researching whether that advance warning could allow doctors to administer separate drugs to beat back the cancer cells, and is also working on a strategy to directly inhibit the mutant enzyme.
The study co-authors include Julia A. Meyer, Jinhua Wang, Laura A. Hogan, Smita Dandekar, Zuojian Tang, Jiri Zavadil, Timothy Cardozo, Elizabeth Raetz, and Debra J. Morrison at NYU Langone Medical Center; Jun J. Yang and William E. Evans at St. Jude Children's Research Hospital; Jay P. Patel and Ross L. Levine at Memorial Sloan-Kettering Cancer Center; Paul Zumbo, Sheng Li, and Christopher E. Mason at Weill Cornell Medical College of Cornell University; and Stephen. P. Hunger at the University of Colorado School of Medicine and Children's Hospital Colorado.
The research was supported by the National Institutes of Health and National Cancer Institute, with additional support from the American Society of Hematology and St. Baldrick's Foundation.
About the NYU Cancer Institute:
The research mission of the NYU Cancer Institute is to discover the origins of cancer and use that knowledge to eradicate the personal and societal burden of cancer in our community and around the world. Fifteen research programs are organized as scientific research programs, focused on the fundamental biology of cancer in general, and as disease-specific research programs centered on individual types of cancer, such as breast or lung cancer. Translational research, a hallmark of the institute, is finding new ways to integrate the extraordinary growth and understanding made in basic research with the ever-growing need for the development of new therapies and approaches in the clinic to a variety of cancers that have remained difficult to treat. To help translate discovery into clinical practice, the NYU Cancer Institute has embarked on five programs that integrate efforts in laboratory investigation and clinical care: cancer targets and novel therapeutics, community and environment, integrative health, molecular oncology/cancer genomics, and immune- and stem-cell-based therapies.
About NYU Langone Medical Center:
NYU Langone Medical Center, a world-class, patient-centered, integrated, academic medical center, is one of the nation's premier centers for excellence in clinical care, biomedical research and medical education. Located in the heart of Manhattan, NYU Langone is composed of four hospitals – Tisch Hospital, its flagship acute care facility; the Hospital for Joint Diseases, one of only five hospitals in the nation dedicated to orthopaedics and rheumatology; Hassenfeld Pediatric Center, a comprehensive pediatric hospital supporting a full array of children's health services; and the Rusk Institute of Rehabilitation Medicine, the world's first university-affiliated facility devoted entirely to rehabilitation medicine– plus NYU School of Medicine, which since 1841 has trained thousands of physicians and scientists who have helped to shape the course of medical history. The medical center's tri-fold mission to serve, teach and discover is achieved 365 days a year through the seamless integration of a culture devoted to excellence in patient care, education and research. For more information, go to www.NYULMC.org.


text:
Vehicle Reviews
Expert Road Test
The Saab 9-3 is completely redesigned and reengineered for 2003. Instead of a quirky-looking hatchback, it's now a sports sedan.
2003 Saab 9-3 Photos
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subset: commoncrawl


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Lightning introduce Season Ticket Programs for the 20th Anniversary Season of 2012-2013
by Staff Writer / Tampa Bay LightningMORE INFORMATION
Highlights in the season ticket packages include per game price decreases of nearly 1,500 promenade (lower) level seats, more than 5,000 seats priced at $18 or less per game on a full season basis and an average per game price increase of just 1% overall. The Lightning's revolutionary micro-chipped jersey concept returns, guaranteeing 25% discounts for food and beverage and 35% for merchandise for all full season seat members. Fans will also notice a 43-game schedule for 2012-13, one more than the 42 played at home in 2011-12, as an additional preseason game has been added to the slate.
"We are pleased to announce our season ticket pricing structure for next season and offer great renewal opportunities now," said Chief Operating Officer Steve Griggs. "We believe our team, the transformed Tampa Bay Times Forum and our in-arena fan experience, combined with one of the lowest average season ticket prices in the National Hockey League, offers tremendous value to our season ticket members."
For the first time in its history, the Lightning is presenting a "Loyalty and Recognition" program offering enhanced benefits and amenities for long-time full season ticket members and other special benefits for season ticket members that regularly attend home games. Additionally, the Lightning will be automatically entering all renewed accounts into their 30 days of prizes giveaway, which features hundreds of thousands of dollars in prizes such as, Busch Gardens tickets, flat screen televisions and trips to the NHL Awards in Las Vegas.
Although limited numbers remain, new full season ticket members committing now for the 2012-13 campaign will receive a micro-chipped Lightning home jersey good for the same great discounts current members are enjoying at all home games. Renewing members will be entitled to these same discounts again next year and all season ticket members for 2012-13 will receive a commemorative Lightning 20th Anniversary patch for their jerseys.
As part of the renewal process, season ticket members can reserve their seats for the 2012 NHL Playoffs should the Lightning qualify. The popular "Cheer Now, Pay Later" plan is available, allowing members to watch Lightning playoff action before paying for their tickets.
For more information on the renewal process, new season ticket purchases, 2012 NHL Playoff Tickets, the loyalty and recognition programs and the 30-day prize giveaway, fans are encouraged to log on to bethethunder.com or call the Lightning sales team at 813.301.6600.


text:
Coffeehouse Thread
3 postsEverything You Always Wanted to Know About Avalon But Were Afraid to Ask
At the end of the last video with Chris Anderson he and Scoble came up with the idea to delve into the nuts and bolts of Avalon in more detail:
Robert: "We're gonna get even more deeper into this in the next few weeks."
Chris: "Yeah, we should sit down with a bunch of people on the team and go through each one of these."
Now this was an exciting promise. I (and I bet most of you too) would love to hear and see more about the components of Avalon. Especially about things that cannot be found in docs or WinHEC slides.
When will the series "Everything You Always Wanted to Know About Avalon But Were Afraid to Ask" kick off?
Actually, that was probably Charles Torre with Chris Anderson, but we're working on a bunch of stuff around Avalon. Check out the Speech API video, for instance, that we just uploaded. That's part of the Avalon bits that were released this week.
The Channel 9 Team wrote:that was probably Charles Torre
Yeah, actually now that I think about it, I did not hear the interviewer laughing out loud ...
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View Benjamen Walker's profile |
A weekly meditation on Who did it, What it is, Where is it at, When it is going down, Why is it not working and How it should be. Add your comments to the playlists in real time or post game.
<-- Previous playlist | Back to Benjamen Walker playlists | Next playlist -->
September 22, 2008: ultrashow
Listen to this show:
Add or read comments
Listener comments! | |
Mon. 9/22/08 9:17am
lance armstrong:
yer nervous about losing your mind, thas' all | |
Mon. 9/22/08 9:17am
Greetings from Boston! How was the Robert Forster show? Did he play the song "Spirit"? | |
Mon. 9/22/08 9:19am
losing my mind indeed! RF show was great - didn't play it in the set I saw | |
Mon. 9/22/08 9:19am
Bad Ronald:
I smell trouble brewing... | |
Mon. 9/22/08 9:20am
Minister Tim:
Each character you meet in your dreams is actually yourself. So... why would you crack yourself over the head with a bike lock? You were simply entering into a dialogue with yourself to resolve some inner conflict you are having. Perhaps about your riding? Sweet Dreams! MT | |
Mon. 9/22/08 9:23am
MT - fascinating.. never heard that one.. that you meet yourself in dreams.. I def won't hit anyone with bike locks anymore! what was I missing I wonder... | |
Mon. 9/22/08 9:26am
not sure about that theory. i dreamt i was in a fist fight with radovan karadzic last night. | |
Mon. 9/22/08 9:27am
whoa.. Owen did you kick his ass? | |
Mon. 9/22/08 9:29am
i think so. definitely connected with a few punches. i didnt lose, thats for sure. | |
Mon. 9/22/08 9:32am
Minister Tim:
Now there is no reason for Ben to hit the bikerider inside himself over the head but it might be right to kick the ass of the radovan karadzic inside yourself! I once had a dream I was DISGUISED as Carl Rove at a republican convention! I was pulling it off until they asked me to say something... I paniced and just started calling everything bullsht... | |
Mon. 9/22/08 9:34am
Owen, you can kick Richard Holbrooke ass too. | |
Mon. 9/22/08 9:35am
In 2000, I had sexual dreams about George W Bush. YUCK. | |
Mon. 9/22/08 9:35am
dream fight!! I think one of the craziest dreams I ever had was when I fought my high school - the actual building! ala Peanuts I didn't win either! Sugarwolf - I don't know what to say!!! | |
Mon. 9/22/08 9:36am
Koen is opening for Om in Greenpoint tomorrow night, FYI. | |
Mon. 9/22/08 9:37am
Bad Ronald:
Doll Man!!! | |
Mon. 9/22/08 9:39am
Bad Ronald:
Any theories on recurring dreams? | |
Mon. 9/22/08 9:44am
Greetings from Lyndhurst, NJ.. nice set here!!.. Suarasama, the Ex.. | |
Mon. 9/22/08 9:48am
go bad ronald! you win! don't got any theories on rec dreams.. but Ken Freedman has a new beard!! | |
Mon. 9/22/08 9:50am
Bad Ronald:
New beard as in facial hair or ruse? | |
Mon. 9/22/08 9:54am
hatch - you goin to that show | |
Mon. 9/22/08 9:54am
this is great, bw | |
Mon. 9/22/08 9:58am
I concur with evan. I had a dream last night that I was swimming in a large pool with polar bears. Any ideas? | |
Mon. 9/22/08 10:08am
bw, you need to play stuff you can pronounce! - hah! Thanks for your dream analysis too. I suspected I was one of the good people but you never really know . . . | |
Mon. 9/22/08 10:21am
I have had WFMU related anxiety dreams! Mostly about forgetting to buy anything at the record fair. Or the marathon ends and I didn't pledge anything. | |
Mon. 9/22/08 10:22am
Sugarwolf brings to mind the oft-related DJ anxiety dream. I've been out of college radio for three decades, and I still have that one once in a while. | |
Mon. 9/22/08 10:25am
Parq, oddly I have never had that DJ anxiety dream. Mine DJ related dreams have been that they are dead. Yikes. | |
Mon. 9/22/08 10:27am
Bad Ronald:
Oh no I miss Roberta! | |
Mon. 9/22/08 10:27am
Being the Doll Man has its disadvantages....indeed Morning all | |
Mon. 9/22/08 10:28am
Bad Ronald:
Send in the clowns! | |
Mon. 9/22/08 10:31am
I had a dream last night that one of our DJs murdered the parents of another one of our DJs. I uncovered the heinous plot, and then the murderer targeted me. Fortunately, I was able to fly faster than the murderess. | |
Mon. 9/22/08 10:32am
Ken Again:
Another Monday morning, another global economic collapse. When is one of these going to stick already? | |
Mon. 9/22/08 10:36am
dc pat:
Who was doing all the killin? | |
Mon. 9/22/08 10:37am
I'vealready said too much. | |
Mon. 9/22/08 10:38am
"mine dreams" ? Oy oy oy..... | |
Mon. 9/22/08 10:40am
Ben, should the comic panels have a heavy tint? Looking at the world through rose colored glasses isn't all it's cracked up to be. | |
Mon. 9/22/08 10:42am
Earl Palmer, RIP | |
Mon. 9/22/08 10:44am
dc pat:
Well it has to be Liz B because she's the only woman DJ that can fly. | |
Mon. 9/22/08 10:44am
Bad Ronald:
Well the first clue "murderess" indicates a female perp. Diane K seems too obvious so my vote is on Liz B. | |
Mon. 9/22/08 10:47am
she isn't here today to defend herself from such accusations.. clearly a sign of guilt!!! | |
Mon. 9/22/08 10:49am
I'd say Bethany or Donna. | |
Mon. 9/22/08 10:50am
well, something was definitely brewing yesterday at ATP... | |
Mon. 9/22/08 10:51am
Bad Ronald:
...Then again Irene T almost ripped my head off for a facetious Yoko Ono comment... | |
Mon. 9/22/08 10:52am
I can't say any more. Except for the fact that the murders were satanic by nature and involved whole fetishistic blair-witch-like talismans made of whole grains. In fact it was the whole grains that gave her away. | |
Mon. 9/22/08 10:53am
a real CLUE!!! | |
Mon. 9/22/08 10:53am
Bad Ronald:
Trouble!?! | |
Mon. 9/22/08 10:54am
I think whole grains implicate Trouble as well. | |
Mon. 9/22/08 10:54am
I mentioned to the DJ whose parents were offed, "I know who killed your parents" (although I didn't). The next thing I knew, the murderess gave Bob Brainen a cloth bag of leftover oatmeal. Then I knew... | |
Mon. 9/22/08 10:56am
Hmm. I was thinking Tamar and Rich. Something internecine. But Ken's additional clue casts a whole different light on the inquiry. Let's form a commission. | |
Mon. 9/22/08 10:56am
The oatmeal matched, you see. Lucky for us, we had Quaker Oats Forensic specialists on-site. | |
Mon. 9/22/08 10:57am
oh man... | |
Mon. 9/22/08 10:58am
Daniel Johnston!! | |
Mon. 9/22/08 11:04am
Some dreamers are left-grained and some are right-grained. | |
Mon. 9/22/08 11:09am
dc pat:
I think I'm going w/ Irene now. | |
Mon. 9/22/08 11:16am
Sean Daily:
Not even close to first comment! Woo hoo! | |
Mon. 9/22/08 11:19am
anyone care to guess who the loop here is by? not as sexy as who the murderess is.. but | |
Mon. 9/22/08 11:21am
Bad Ronald:
now it's turning into "Watching the Detectives"... | |
Mon. 9/22/08 11:25am
dc pat:
hmmm, what does Vicki eat for breakfast?? I forgot about her. She doesn't strike me as the whole-grain type but, she might be good at killin folks and she can fly. | |
Mon. 9/22/08 11:25am
its the beginning trill from mulatu astatke's tezeta version | |
Mon. 9/22/08 11:27am
whoops not mulatu but getachew kassa | |
Mon. 9/22/08 11:29am
dc pat:
crap, I was going to say one of those Ethiopian cats | |
Mon. 9/22/08 11:42am
Mao Jones:
Dow down 217. Trust us!! | |
Mon. 9/22/08 11:44am
high places! | |
Mon. 9/22/08 11:45am
what are we listening to right now? I kind of like that girl's voice | |
Mon. 9/22/08 11:46am
that was the high places 45 josh | |
Mon. 9/22/08 11:48am
thanks! say.. long shot but If you can find Michael Hurley's 'I Paint a Design' that'd be great! | |
Mon. 9/22/08 11:48am
This could be her: http://www.flickr.com/photos/wfmu/109830119/ Stone Kold Killah | |
Mon. 9/22/08 11:48am
ken freedman has a new beard? Is this to cover the deformity he was talking about a few weeks ago? | |
Mon. 9/22/08 11:53am
I saw him over the summer before he grew his beard and it wasn't pretty. Poor guy. | |
Mon. 9/22/08 11:55am
Bad Ronald:
I would call it a "FreeFormity"! | |
Mon. 9/22/08 11:54pm
I do like the picture up there. | |
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text:
The North Face Splasher Rash Guard
Fabric |
84% Recycled Polyester, 16% Elastane |
Retailers' Descriptions
Here's what other sites are saying:
Keep your infant warm and safe from the sun at the beach or pool with The North face Infant Splasher Rash Guard. You are never too young to play in the water, and this rash guard offers great sun protection and added warmth so your child enjoys the water, too. A playful take on The North Face logo adorns the front.
- Altrec Outlet
Take the worry out of your baby boy's first trip to the beach and dress him in The North Face Splasher Long-Sleeve Rashguard. The stretchy fabric not only offers all-day protection from burning rays, but it dries quickly when he gets splashed as you hold his feet in the foam at the edge of the sea.
- Backcountry.com
Your baby is as comfortable in the water as in your arms. That's why this top, made of moisture-wicking fabric, will get plenty of wear.
- The North Face
84% recycled polyester, 16% elastane. 84% recycled polyester, 16% elastane Wicking fabric Ultraviolet protection factor (UPF) 50 Screen-print at center front chest
- Rocky Mountain Trail
Summer is about splashing, and having fun in the sun. Protect your baby, in The North Face Infant Splasher Rash Guard, delivering excellent UPF 30 sun protection for baby's delicate skin. Grab this 4-way stretch, quick drying top when you head out to the kiddie pool or pack it for vacation, to keep your little one comfortable and safe.Constructed of 84% polyester, 16% elastane. 4-way stretch fabric guarantees complete mobility.Wicking fabric for quick drying comfort.Ultraviolet protection factor (UPF) 30.Screen-printed artwork at chest.Import.
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The North Face Splasher Rash Guard is not available from the stores we monitor. It was last seen January 30, 2013 at Altrec Outlet.
If you're looking for a new long sleeve rashguard, check out the best reviewed current models.


text:
good chemistry is complicated, and a little bit messy -LW |
PerlMonks |
Re: Re: Apache::Filter and Apache::RegistryFilterby thraxil (Prior) |
on Nov 19, 2003 at 20:02 UTC ( #308392=note: print w/replies, xml ) | Need Help?? |
i think you've got it. i changed my test script from: to: and it seems to work now. do you know of any way to make it work with the former style. i usually take as much advantage of Registry's CGI emulation as possible so i can run scripts as either CGI or Registry. i know i can just put: into everything, but i'd rather not have to retrofit all my apps just to make them filterable. at least i know that if i upgrade to apache2, i can make anything filterable with the native filtering API. :)
In Section
Seekers of Perl Wisdom


text:
Monday, 8 March 2010
Maybelline Magnum Volum'Express
Stand a chance to win this Magnum Sports Bike with purchase of the new
Maybelline Magnum Volum'Express
mascara at the Watsons in Ngee Ann City!
Isn't it a beauty?
Details of how to enter the contest are below.
1 comment:
♥ Starryxuan
The bike is soo cute! I bought and lost the receipt already :(
8 March 2010 at 21:30
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text:
Phusion Releases Passenger Enterprise 4
Phusion Passenger 4 offers improved scalability, Python WSGI support, multithreading, and better error diagnostics.
Phusion has released Phusion Passenger Enterprise 4.0 beta 1. According to the website, this version includes improved scalability and concurrency as well as dramatically improved internal architecture.
According to the project website, "Phusion Passenger is an Apache and Nginx module for deploying Ruby and Python web applications. It has a strong focus on ease of use, stability and performance. Phusion Passenger is built on top of tried-and-true, battle-hardened Unix technologies, yet at the same time introduces innovations not found in most traditional Unix servers."
The changes in Phusion Passenger 4 include support for multiple Ruby versions, Python WSGI support, multithreading, improved zero-copy architecture, better error diagnostics, and support for JRuby, and Rubinius. This means you can now run multiple Ruby versions at the same time in the same Phusion Passenger instance. Additionally, Phusion Passenger's I/O handler has been completely rewritten and is now "evented" just like Nginx and Node.js.
Phusion Passenger 4 also introduces real-time response buffering. Unlike traditional response buffering, Phusion Passenger sends data to the client immediately, while still relieving the application from slow clients, the website said.
Issue 198/2017
Buy this issue as a PDF
Old Linux Kernel Bug Discovered
The bug was introduced back in 2009 and has been lurking around all this time.
OpenSSH 7.5 Released
The new release deprecates the sshd_config UsePrivilegeSeparation option.
Ubuntu Touch Not Dead
Lives on as a community project
Dell Launches Five New Linux Systems
Five new systems join Dell XPS 13 Developer Edition that come with Ubuntu pre-installed.
Microsoft Takes Skype for Linux Out of Alpha
The Skype Linux client now has almost the same capabilities that it enjoys on other platforms.
CeBIT 2017 OpenStack Day
At CeBIT 2017, OpenStack Day will offer a wide range of lectures and discussions.
Munich Plans to Ditch Linux and Go Back to Windows
A major setback for the Linux desktop.
Linux Kernel 4.10 Comes with New Security Features
Improved support for GPU in virtualization.
OpenSUSE Site Hacked
News site for the openSUSE community falls victim to a Wordpress exploit.
LibreOffice Goes Online with 5.3 Release
The source code is available online.


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Montrose Elementary receives grant for 'recess renovation'
Citizen Staff Reports 11/08/12
Montrose Elementary School students jumped rope, played hopscotch and participated in games of foursquare recently on their newly painted blacktop during recess. But now, recess for Montrose students is a bit different. With the help of a grant from Capital One, Montrose was able to launch "Organized Recess," a time of day where students can participate in cooperative games that double as "teachable moments" in the areas of social skills and good citizenship.
"We have done some research and gathered that organized recess decreases discipline incidents," said Montrose Principal Dana Baldacci. "So we decided this year we'd do several days a week of organized recess, and through this grant, we are able to do it."
Capital One volunteers came out early in the week to repaint the blacktop and then again later in the week to show students how to safely use the equipment in a variety of games that aimed at fostering participation and fair play (pictured). Each classroom also received a bucket full of new recess materials that encourage students to interact and play with one another in a collaborative way.
"This is a great opportunity that Capital One gives us to give back to the community and the neighborhood," said Tim Gunn, a Capital One employee. "It's been a great experience, one of the kids even said it was better than field day, so that's just sort of the icing on the cake for us."
HCPS wins national honor for overhaul of Code of Student Conduct, supports
Citizen Staff Reports 03/28/2017 Education
Henrico County Public Schools recently was recognized by the National School Boards Association for a sweeping overhaul of the school division's approach to student supports. HCPS was one of five large U.S. school systems recognized with a first-place honor in the 2017 Magna Awards, presented Saturday in Denver at the organization's annual conference. The awards recognize school divisions and leaders "for taking bold and innovative steps to improve the lives of students and their communities," according to the group.
The award recognizes Henrico Schools' efforts of the past several years, from re-examining its policies to implementing more support systems. After a two-year conversation with the community through public hearings and other feedback, HCPS adopted a revised Code of Student Conduct for the 2015-16 school year. > Read more.
Environmentalists say budget hurts efforts to protect bay
By Julie Rothey, Capital News Service 03/28/2017 Government
Environmental groups are outraged at the Trump administration's proposed funding cuts for Chesapeake Bay cleanup programs.
President Donald Trump's budget plan, released last week, reduces the budget for the federal Environmental Protection Agency by 31 percent. That includes a $427 million in funding to address regional pollution, such as the Chesapeake Bay protection efforts. The proposed budget would eliminate funding for the EPA's Chesapeake Bay Program, which received $73 million from the federal government in 2016. > Read more.
President Donald Trump's budget plan, released last week, reduces the budget for the federal Environmental Protection Agency by 31 percent. That includes a $427 million in funding to address regional pollution, such as the Chesapeake Bay protection efforts. The proposed budget would eliminate funding for the EPA's Chesapeake Bay Program, which received $73 million from the federal government in 2016. > Read more.
Glen Allen ES principal receives REB Award
Citizen Staff Reports 03/28/2017 Education
Melissa Halquist-Pruden, principal of Henrico County's Glen Allen Elementary School, earned the 2016-17 REB Award for Distinguished Educational Leadership. The Community Foundation presents the award to four principals annually – one each from the school systems of Henrico, Chesterfield and Hanover counties and one from the city of Richmond schools.
The award recognizes principals who go beyond the day-to-day demands of their jobs to create an exceptional educational environment. The award stresses management and communication skills, and the ability to inspire, encourage and advocate for the school. > Read more.
Grant to help Hermitage H.S. upgrade CTE program equipment
Citizen Staff Reports 03/27/2017 Education
Governor Terry McAuliffe announced recently that Henrico County's Hermitage H.S. will be among 16 high schools and technical centers statewide to receive a grant to upgrade equipment for career and technical education (CTE) programs.
The program gives priority to challenged schools, Governor's STEM Academies and Governor's Health Science Academies. Each school or center will receive $37,500 to purchase new equipment and make other necessary improvements. At Hermitage, the funds will be used for precision machining equipment. > Read more.
Virginia raises a toast to George Washington's whiskey
By Megan Corsano, Capital News Service 03/27/2017 General AssemblyGeneral Assembly 2017
George Washington is recognized as the father of our country, but with a bill signed into law by Gov. Terry McAuliffe, Washington also will be recognized under another title – distiller of Virginia's official liquor.
SB 1261, sponsored by Sen. Adam Ebbin of Alexandria, adds a "state spirit" to the list of the commonwealth's official emblems and designations and crowns George Washington's rye whiskey with the title.
The bill, which McAuliffe signed last week, highlights George Washington's contributions to the culture of Virginia as "a native son of Virginia born on February 22, 1732, in Pope's Creek"; "the first American president, commander of the Continental Army, and president of the Constitutional Convention"; and "a model statesman ... universally acknowledged as the father of our nation." > Read more.
Villa's Flagler Housing wins national NAEH award
St. Joseph's Villa's Flagler Housing & Homeless Services was one of three entities to earn the National Alliance to End Homelessness' Champion of Change Award. The awards were presented Nov. 17 during a ceremony at the Newseum in Washington, D.C.
NAEH annually recognizes proven programs and significant achievements in ending child and family homelessness.
Flagler completed its transition from an on-campus shelter to the community-based model of rapid rehousing in 2013, and it was one of the nation's first rapid re-housing service providers to be certified by NAEH. > Read more.
RIR's Christmas tree lighting rescheduled for Dec. 12
Richmond International Raceway's 13th annual Community Christmas tree lighting has been rescheduled from Dec. 6 to Monday, Dec. 12, at 6:30 p.m., due to inclement weather expected on the original date.
Entertainment Dec. 12 will be provided by the Laburnum Elementary School choir and the Henrico High School Mighty Marching Warriors band. Tree decorations crafted by students from Laburnum Elementary School and L. Douglas Wilder Middle School will be on display. Hot chocolate and cookies will be supplied by the Henrico High School football boosters. > Read more.
Weekend Top 10
For our Top 10 calendar events this weekend, click here! > Read more.
Virginia raises a toast to George Washington's whiskey
McAuliffe vetoes 6 more bills; GOP calls him 'disengaged'
HSWCD to give away tree seedlings Thursday and Friday
Dog rescued, no one injured in Northside townhouse fire
Walk, ceremony to observe Crime Victims' Rights Week
- More News
Print Edition
Mar. 16, 2017
Click here to read the print edition.Entertainment
Weekend Top 10
Metro Diner to open second Henrico location
CAT Theatre to present 'When There's A Will'
Weekend Top 10
Weekend Top 10
- More Entertainment
Obituary – Michael Lee
Obituary – Esther Jeanette Windmueller
Obituary – Anthony Nicholas Laudani
- More Obituaries
Villa's Flagler Housing wins national NAEH award
RIR's Christmas tree lighting rescheduled for Dec. 12
project:HOMES' 'Renew Crew' helps Henrico citizen
- More Community
Make 'em take the pledge: no more snuff boxes!
Thanksgiving, Part II
Storm woes for e-junkies
- More Opinions
Highland Springs girls fall in state title game
RIR to admit children 12 and younger free next year
Henrico teams win district, state championships
- More Sports
← | March 2017 | → | ||||
Place an Ad | More Classifieds
The Central Virginia Disaster Survivor Day training in Henrico County will be held from 9 a.m. to 12 p.m. at the Henrico Public Safety Training Center at 7701 E. Parham Rd. This free course is designed to introduce you to general emergency preparedness and safety information, and to provide each registered address a free backpack to take home and develop your own disaster survival kit. Learn about weather awareness, household safety, first aid and hygiene, planning and documents and basic active shooter awareness. For details, visit http://www.survivorday.com. Full text


text:
Tropical Fish Keeping - Aquarium fish care and resources
- Beginner Saltwater Aquariums
- - Starting My First Saltwater Tank and I have a few Questions.
Starting My First Saltwater Tank and I have a few Questions. Hey All! I am new to the forum, have been doing some research for the past couple of days and looking at what i need to buy. I currently purchased a 55 gallon tank and want to make a saltwater tank. I currently have nothing other than the tank and stand and some old powerheads and hang on filter that the PO gave me with the tank. My plan is to start with RO water from my local store and add instant ocean to that, and let it run with the powerheads in the tank for about 3 days. I then will add my live rock, probably starting with 50 lbs or so, and then add my live sand. My questions are: 1: how much sand do i need in lbs? 2: Does my water need to be stable in PH or nitrates prior to adding rock or sand? I dont believe so, but i dont want to risk screwing this up from fear of asking a stupid question. 3: I have an old hood light that came with the tank, it has a 37" fluorescent 40W light bulb. Can i just replace the bulb, or do i need to purchase an entirely new light. If i can get by with just the bulb for now, and buy a light later, that would work best as i am soon going to be paying out alot on my skimmer, sump, overflow and other essentials. 4: If there is anything i am missing, please let me know! 5: I am getting a Pro clear aquatics aquarium sump, measures approx 19L x 10W x 16H from someone off Craigslist here in my town on friday. Will this be sufficient to run my tank without any other filtration system, or do i need a canister filter or over the tank filter? Lastly i want to say thanks to anyone who responds and thanks for every ones knowledge that i have spent the last days reading!:yourock: |
My method of filtration is 1-1/2 lbs of live rock per gallon, a deep sand bed (4-6" of oolite sand) and a protein skimmer. The deep sand bed and live rock provide anaerobic bacteria that turns nitrates into nitrogen gas (which leaves the system naturally). You can add the live rock and sand to the tank, no matter the pH (although the pH should be fine based on the salt mix and lack of nitrifiers present in the tank) and they will cycle the tank almost immediately. I would replace the bulb for now and save up for a light later. If you do plan on doing corals, you will need to upgrade the light sooner than later. Start a thread that can be a journal, and take things slow. We will help you along the way. |
What type of bulb should i go with to replace my current one. I will want to do some coral, but it will likely not be for at least 6-8 weeks at the soonest. Ive done some looking at lights online and its hard to find a replacement bulb for my lid that isn't just the basic fluorescent light. Also im looking at getting the octopus pinwheel skimmer NWB110. Is this decent and able to keep up with me tank? My research so far show it to be good. Thanks! |
What kind of light is it? What is written on the bulb? |
Also do i need two lights? one for day and one for night? |
If you only have one bulb for now, use a 50/50 bulb. That is 50% 10,000k and 50% 460nn actinic. |
So it measures out at 1 inch, therefore im thinking that means it is a t8. There is no other writing on it than "Philips softtone fluorescent f40/sf 40 watt. And down from the writing a bit it has a 5A on it. Im thinking i may just break down and buy a new LED light for the tank. how does Fluval Eco Bright LED Aquarium Strip Light at PETCO or Marineland LED Single Bright Aquarium Lighting System - LED Light Aquarium and Aquarium LED Light Fixtures from petco.com look for a replacement? |
While LEDs are nice energy-wise, you have to spend real money to get a quality fixture. These two that you have posted would be good for a fish only tank, but I am not confident about coral growth under them. I have never used either, I have a Green Element LED that I bought off ebay that I am not happy with, and it is more powerful than either of these at 10 x 3w bulbs. I am in the process of shopping and changing over to a 4-bulb T5 fixture. That has always been my favorite kind of lighting... I would use this: http://www.drsfostersmith.com/produc...00&pcatid=4500 until you get a new fixture. |
Ok, ive been doing some looking. I think im going to just break down and buy me a new light. However its just kind of cringe worthy to see the 350+ price tags on these things. Do i need a 4 bulb, or would a two bulb t5HO be sufficient. I want to get some anemone and things similar down the road. Ive been looking at three lights. Coralife Dual Fixture High Output T5 Aquarium Light Fixture at PETCO http://www.amazon.com/Coralife-Aqualight-Output-Fixture-48-Inch/dp/B0049PU8BI/ref=cm_cr_pr_product_top http://www.marineandreef.com/AquaticLife_48_T5_HO_4_Lamp_Fixture_Lunar_Light_p/ral01037.htm Also i am guessing since my tank is 48" long, i will need the 48" light. If i am wrong here, please correct me. Thanks again for all your help. I purchased my salt mix, hydrometer, skimmer, overflow, thermometer, heater, and test kits yesterday, so im getting there slowly but surely. |
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text:
In many cases a simple idea is also the best one. The curved wall mounted wardrobe from Phos is appealing and simple with its half circle. The soft lines snuggle to the wall and thereby look elegant and stylish.
The form offers enough space for numerous clothes hangers so that several jackets, coats and other clothes find their place in the wall wardrobe.
Arranged beside each other, the hangers support the bent form so that the design has an equal effect when the wardrobe is full.
The arched wardrobe is made out of solid stainless steel and hand-grounded. This procedure makes it a high quality product that convinces with a simple and elegant design as well as with its practical advantages.
The arched wall wardrobe is also available in a length of 120 cm.


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Rich Dad Poor Dad will….
Robert Kiyosaki has challenged and changed the way tens of millions of people around the world think about money. With perspectives that often contradict conventional wisdom, Robert has earned a reputation for straight talk, irreverence, and courage. He is regarded worldwide as a passionate advocate for financial education.
"The main reason people struggle financially is because they have spent years in school but learned nothing about money. The result is that people learn to work for money… but never learn to have money work for them."
Robert Kiyosaki Rich Dad Poor Dad – The #1 Personal Finance Book of All Time!
"Rich Dad Poor Dad is a starting point for anyone looking to gain control of their financial future." (USA Today)
©2011 Robert T. Kiyosaki (P)2012 Brilliance Audio, Inc.
"Very Motivating"
I would recommend this book to anyone who is looking for motivation to ignore any excuses and doubts and take control of their own financial situation.
The use of the dichotomy of the"rich Dad" and the "poor Dad" to explain the differences in thinking and financial attitudes works perfectly.
This is much better than any other book about finance I have come across in the past simply because it is much less boring and actually quite entertaining. It was very refreshing to not be forced to wade through chapters upon chapters of mind numbing drudgery, as is the case with most books about financial matters.
After finishing Rich Dad Poor Dad I experienced a renewed enthusiasm to work towards financial freedom. It presents the information in a manner which is easy for the layman to understand and digest, and is very effective in leaving the reader feeling energized and enthusiastic.
"Great Book - Bad Narrator"
Robert - Yes
Tim - No
The narrator was constantly swallowing and making disgusting noises when he wasn't talking. The noises are loud and extremely unpleasant, especially when listening on earphones.
The content was good.
"Just Amazing"
Priceless words of wisdom about money and finance.
Great read. Must be read. the story is very nice. and the content is very rich.
"Focus on your Assets....the end"
I've not read the print edition.
Other investing/business type books, nothing specifically as it has it's own twist on things.
Anybody else.
Focus on my balance sheet and less on my income statement.
This book can be summed up by saying, focus on your balance sheet and overcome obstacles when they're presented.
The book is very good!. The reader, Tim Wheeler, has not received proper breathing instruction to narrate a book. Some people don't breath while they speak. This is not a healthy habit. It is distracting to listen to a book where the reader holds his breath and gasps between pauses. It actully interrupts my breathing while listening to him.!!!
"Great beginner's guide into the world of the rich"
R. Kiyosaki combines his experiences as a young man and rising investor and translates the lessons he had learned then into this audiobook. It it wonderful to absorb the philosophy of a wealthy person. Finishing this book in lieu of the 2016 U.S presidential elections, however, I find myself at odds considering D. Trump as a "hero." I ask you to take this book at face value and combine it with your own insight. Do not accept everything you read/hear in this book, but do understand the underlying philosophies.
"simplistic and self satisfied"
more research and less boasting; more solid information not just anecdotes
this author
basic points are good but never elaborated upon
"Worth listing to"
This is worth more than just about anything I've read or listened to. It has changed my thinking and my life.
20 something loving personal development and financial learning.
"great and simple"
of course, it was easy to follow and very motivational.
the rich dad, he was funny
yes, it made me dedicate myself to learning about investing.
read it, should change your thinking.
"Surprisingly Close-Minded"
Kiyosaki listened to both dads, thought about the advice, and made his decision. I thought going into the book that it would be a presentation of the two different perspectives. Instead it was the bashing of one and exalting of the other. Not that I disagree with rich dad or agree with poor dad, but I would have appreciated the book more if it would have presented the ideas in a more non-biased format, and shown the results of the two types of advice.
Good points are made, I just wish they'd have been presented differently.
"I'll be buying assets from here on!"
I really enjoyed this book. It teaches you the mentality that drives wealthy people and the core principles that made them rich. I am putting these principles into action.
This book encapsulates capitalism and for the most part whatever your philosophy, the advice is sound...at least from a 'Western' stance. Kiyosaki is clearly very passionate about the subject matter which adds an air of confidence and authority to his book. Some have criticised that the whole,'rich dad' thing is a fabrication...I would suggest that this is an irrelevance. Any successful entrepreneur will tell you that acting 'as if' is often a given. Kiyosaki can get carried away at times and make what I would say are ridiculous suggestions such as education being for mere fools......and this lets an otherwise excellent book down. At times, Kiyosaki apologises for being unfair...and then continues to be just that and there can be a two-faced element to his arguments as a consequence. Narration is always important with audiobooks and Wheeler's approach is impeccable. I'd encourage Kiyosaki to take some time out to embrace some more Eastern practices as money alone whilst important is ultimately a mere fabrication of mankind. Nevertheless a very enjoyable listen...if at times a tad trite.
"Fantastic book!! Very useful"
The narration of the book is really fantastic, Tim Wheeler has great voice.I also like different topics that are covered around this book. It gives an idea of how we can train our children about finance and also there is a lot adults can learn and think about the financial information provided in this book. Author has not only gave us thought process but also gave an idea of how to start with it. It changed my perspective of thinking towards money, rich people and managing our finances.
"An enjoyable,outstanding eye opener !!"
I will 110% be listening to this audio book again as I feel that there was too much valuable information to take in all at once, next time I will be taking notes and using them to begin educating my own children. I listened to the whole book within 24hrs as I just wanted to know more and since finishing the book I have bought 3 more of Rich Dads audio books.
Tim Wheeler was a great candidate for Rich Dads audio books as he made the listening experience more pleasurable with his tone of voice and delivery of speech. He also has the ability to make you feel as though he is actually sitting beside you and talking to you personally.
It made me feel a little bit angry at times as I felt like the working class are actually kept in the dark about a lot of the topics spoke about in this audio book. It also aggravated me to think that my children are now also being "Trained" at school to become only suitable for employment. I have since been proactive about changing my children's course of education and also about they're financial way of thinking. A definite must have for any loving, caring parent.
For any one serious about opening there mind and changing the way they see things I would highly recommend. A small price to pay for potentially life changing information!!
Understanding the difference between 'classes' and assets/liabilities for me personally. I thought the whole book was good as an audio book.
"Badly read"
I haven't finished listening to this book yet and one of the reasons it's taking me a long time to get through is that it's read in a very monotonous tone, which makes the material feel more boring than it needs to.
But I also have problems with the content of the book, since the author spends so much time telling us to accumulate assets instead of liabilities, but doesn't really get down to the nuts and bolts of how to do that, which is frustrating.
"Motivational but thin on details."
This is a bit of a mix, really, and there are some issues.
It seems America-centric. A lot of the advice offered is not directly relevant to other countries because the laws are different. For example, in the UK it is not necessary to set up a corporation to claim business expenses offset against tax; you can instead set up as a sole trader or partnership.
It also does seem that Kiyosaki is cherry-picking when it comes to anecdotes offered. This may or may not be the case, but it is the feeling I get. He seems to go off on a rant when talking about an investment that increases in value by 16% year-on-year because he's been told by other people that the investment is "far too risky," but he does not explain the investment.
Nevertheless, some of the advice I do feel is sound. To own businesses (rather than taking time to run them yourself) and to learn to make good investment decisions and make them both seem good ideas from the point of view of the end goal of generating money without working for money. That's obviously the ticket to financial security which is what the book is really about. If you have a regular income and you don't have to "work" 40 hours a week to get it, that's the goal.
The problem for me with this book and many similar books is that it describes what has worked for Kiyosaki. Kiyosaki has a unique set of skills as has every other person. In his case it led to riches; in other people's cases that may not really apply.
"An Inspiration"
An inspirational book. Recommend this book highly if you want to learn how to take control of your finances and make money work for you!!!
"Inspiring, entertaining and insightful"
This book totally lived up to the hype. Inspiring stories and advice on all aspects of wealth creation as well as some nice spiritual observations.
"this is a must listen"
This is a must listen for everyone. Give it to your Dad too (rich or poor), your mum, your friends and your kids. Espeically your kids.


text:
Project by senomozi | posted 07-14-2010 04:35 AM | 4455 views | 44 times favorited | 46 comments |
This project only took three years to complete! Finally completed it yesterday. It was a personal project so other ones always seemed to take priority over this one and I only worked sporadically on it. My goal was to design and build something really distinctive and use it as a showcase piece for my business. I wanted something small packed with many different woodworking techniques. The inspiration for this piece is a Shaker candle stand.
It is made out of flame birch and black walnut. The top is diamond matched walnut burl veneer glued to a baltic birch substrate with light coloured solid walnut banding around the perimeter. The leg assembly is finished with polymerized tung oil. The top is finished with shellac that was rubbed with Micro-Mesh discs up to 12000 grit.
14" deep x 14" wide x 25 1/2" high.
Woodworking techniques featured in this piece:
- Diamond matched veneering
- Through mortise and tenons
- Double tapered legs
- Banding
- Bent laminated stretcher assembly
- Mortise and tenon joints between stretcher and legs and between apron pieces and center hub.
-- Senomozi - Gatineau, Canada
46 comments so far
#1 posted 07-14-2010 04:39 AM |
This is why I like spending time here! Getting a chance to see something as nice as this is a real treat! Beautiful design and the materials are great! -- Steve - Impatience is Expensive |
#2 posted 07-14-2010 05:03 AM |
What a beauty! Excellent work -- ~ Inspiring those who inspire me ~ |
#3 posted 07-14-2010 05:06 AM |
You've definitely created a showcase piece! Nice job. -- Cal Noguchi - EZdado.com |
#4 posted 07-14-2010 05:07 AM |
My guess would be that if you were wanting something distinctive you hit the mark right on very nice indeed…..................Schloemoe -- schloemoe, Oregon , http://www. woodrehab.blogspot.com |
#5 posted 07-14-2010 05:12 AM |
Very good design and craftsmanship. |
#6 posted 07-14-2010 05:14 AM |
An absolute beauty. Isn't it funny how the amount of time a project takes is inversely porportional to the amount of material in it? |
#7 posted 07-14-2010 05:16 AM |
Awesome design, great job! -- Z, Rockwall, TX |
#8 posted 07-14-2010 05:18 AM |
Wow. This is absolutely amazing. -- Lis - Michigan - http://www.missmooseart.com - https://www.etsy.com/people/lisbokt |
#9 posted 07-14-2010 05:31 AM |
Exquisite detail and design. Unique and very nicely done. Thanks for posting. God Bless -- Mc Bridge Cabinets, Iowa |
#10 posted 07-14-2010 05:31 AM |
I know you book matched the burl but it is mighty difficult to see as you did such a superb job of it. The rest of the craftsmanship is absolutely outstanding. Any museum or art shop would be honored to have it. Erwin, Jacksonville, FL -- Erwin, Jacksonville, FL |
#11 posted 07-14-2010 05:58 AM |
Very impressive and technical. All you need is a candle! -- "Once more unto the breach, dear friends..." Henry V - Act III, Scene I |
#12 posted 07-14-2010 07:04 AM |
It looks like you burnt the candle on both ends making it! Hats off to an excellent piece. -- Style is simple, but not my execution of it. |
#13 posted 07-14-2010 08:43 AM |
Excellent work. -- www.woodworkerlazar.com |
#14 posted 07-14-2010 10:30 AM |
This is something else. What a great job and so different than most tables. Something to be proud of for sure! -- Ken, "Everyday above ground is a good day!" |
#15 posted 07-14-2010 12:27 PM |
Outstanding work…. -- Dan ~ Texarkana, Tx. |
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text:
Japanese sweets
Посмотреть похожие темы
Japanese Sakura Sweets
The Japanese have long established themselves as the experts of cute. When it comes to food, they can make it so awwdorable, that you will cry bitter tears blaming yourself for having eaten that sugary kitten. A&D is on a mission to compile the ultimate list of both cute and mouth-watering Japanese sweets. Post your pics or upvote the cutest ones, let's make the world a sweeter place! (H/T: Bored Panda)


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After working behind the scenes, more or less, as a straight-up producer for the likes of Kanye West and Notorious B.I.G., Nottz is looking to get some much deserved shine later this month. In less than two weeks, his solo debut, You Need This Music, will be released. And while it boasts a number of features, as you can hear on "The Cycle" with Joell Ortiz, this album is about displaying Nottz's abilities as both a producer and an MC. While Ortiz might be the more charismatic of the two on here, Nottz holds his own with a tight, in-the-pocket flow akin to many of the better producer-rappers of our time.
You can stream the soulful piano-laced "The Cycle" here. You Need This Music drops Oct. 26.
El Guincho - "Novias" (Live On Tunnelvision) (Video) | Mark Ronson "Somebody To Love Me" f. Boy George & Andrew Wyatt (Video) |


text:
In this edition are two shows that feature several of the frequently heard voice actors that supported the stories and populated the world of Sam Spade with entertaining characters. Included are bios of Laureen Tuttle, Joe Kearns, Alan Reed, and Hans Conried.
Celebrated for its light-hearted approach and breezy banter, the Spade series was a popular hit.
©2009 Renaissance eBooks Inc.; (P)2009 Renaissance eBooks Inc.
"This is misrepresented"
Terrible not the radio show itself,, it's just talk about the show, who was in it
Very disappointed
"Howard Duff is no Humphrey Bogart"
It may have been popular at the time, but it doesn't age well.
The plot is confusing, Spade's logic escapes me and his relationship with Effie is atrocious. I really didn't like the character.


text:
There are currently 7 Travel Helpers for Cyprus. Please remember that these Travel Helpers provide information on a volunteer basis and when they take the time to help you that a thank you is highly appreciated! They are listed below in order of their last activity on Travellerspoint.
I live here and work with travellers so I collect information.
(Or go out and find it!)
AND ... I can be reached at: firstname.lastname@example.com
Turkish Cyprus. Almost annual visitor since 1991. Not much help on hotels!
Any sort of travel advice, from what to see & do, where to stay, eat, drink, buy and more...
Able to help all sort of travellers.
I was born In Cyprus and so I know it well. The fact that I have studied in the States and in the UK allows me to know how young people from those or similar areas like to party. So I can offer advice on where to go and what to do in order to save time and make the most out of your trip in Cyprus!
Information on history geography and
holiday info, prices etc
No Cyprus questions; but all the answers on Cyprus travel?
Here are some other Travellerspoint pages to help you plan your trip to Cyprus!


text:
Note: Like New, Customer Return, Tested & 100% Working.
Mocole X05 Wireless Bluetooth 1800mAh Li-Ion Rechargeable Speaker with Built-in Speakerphone (Aluminum Alloy Casing)
Learn MoreRegular Price: $79.99
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SimplyShred's POD-2 desktop portable shredder is a space saver. Its small design allows for easy storage on a desktop bookshelf or table.
Learn MoreRegular Price: $149.99
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The KERO cable weight works with your original iPhone 5 cable to easily convert into a weighted dock. May not work with aftermarket lightning cables like the AmazonBasic cable.
The KERO Cable weight is a luxury cable management dock. Watch the video on kickstarter for more information!
NOTE: Apple Lightning Cable NOT INCLUDED.
Learn MoreRegular Price: $24.99
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text:
Representatives from 51 of Colorado's 63 counties will meet for three days this week to discuss local and state issues during the winter conference for Colorado Counties Inc.
Hot topics are likely to include the state's budget and water resources.
Routt County's three commissioners, along with other county employees, will attend the meeting in Colorado Springs.
The conference offers a chance to learn about important issues from the experts, Routt County Commissioner Doug Monger said.
Monger is the president for the western district of Colorado Counties Inc., which includes 16 counties such as Moffat, Rio Blanco and Garfield counties.
"It's an opportunity to get all of the commissioners there at a meeting and talk about all of the issues at one time," Monger said.
Because the conference also involves representatives from counties' human services and road and bridge departments, it allows for broader discussions and bigger-name speakers.
This year, Gov. Bill Owens, is scheduled to be one of more than two dozen speakers. Others will include State Sen. John Andrews, Ted Trujillo, the state director of the Child Welfare Division, and John Pape with the Colorado Department of Public Health and Environment.
The conference will focus on several issues important to the state, Monger said, the first being the state's budget.
"Next year's state budget ... is a big one that we're very concerned about," Monger said. The conference could provide insight for how the state will regroup and "move forward from our current budget situation," he said.
Another top issue is water demand and supply across the state. State representatives will have to consider options for firming up water supplies after voters defeated Referendum A at this year's election. The bill would have created a $2 billion loan program to finance water projects.
Other important issues most likely will include forest health, transportation and the threat of terrorism.
In past years, growth management has topped the list of topics, but this year, Monger said he expects the state's budget and water resources to be the focus.
"We have the stagnated economy and all of a sudden, growth comes off the table," Monger said.
Most important, the conference offers a chance for county officials to talk with other county officials. Routt County commissioners likely will spend time talking with Grand County commissioners, Monger said, as Routt and Grand counties have court orders to build justice centers.
"It's a good opportunity to network," Monger said. "I think that's the biggest thing."


text:
Mercury Marine 134-3736 Trigger - CDI Electronics
4 & 6 Cyl Distributor Trigger Housing
NOTE: Requires the STEEL TRIGGER DISK included.
Fits most 1970-79 4 and 6 cylinder engines.
Replaces OEM #:
- Mercury 332-4177A 3
- Mercury 393-3736A 3
- Mercury 393-3736A23
- Mercury 393-3736A77
- Mercury 393-3736A79
Unit includes the 4 & 6 cylinder trigger disks, oversize spacer, bearings, snap ring and instructions. Improved design uses Hall Effect technology for improved performance and ease of installation (Removeable disk cap is replaceable)
This product ships in 1 business day.
Add to Cart and enter your Postal Code to determine the shipping charges.
Most products and orders leave our warehouse in 1 business day. However, select items may take more processing time. Alaska and Hawaii orders please add 1 additional warehouse processing day.
Standard Shipping Policies


text:
Need a fence or fence repair? Would you like to help save more senior dogs?
Tell Top Notch Fencing & Construction that "Seniors Rock! – Saving the Seniors" sent you, and a percentage of sales will be shared with the rescue!
(414) 331-4786
Mission Statement
Seniors Rock (Saving the Seniors) is a non-profit organization dedicated to the rehabilitation and care of primarily senior abandoned, neglected and homeless dogs within the state of Wisconsin, with the goal of finding them safe, loving, forever homes.
Wisconsin State License = DATCP # 400615-DS
Welcome to our new adventure,
Seniors Rock! – Saving the Seniors.
We are a group of dedicated volunteers in Wisconsin that, after working in animal rescue for years, saw the need for a group to help seniors dogs that find their way to our shelters.
Seniors Rock is a network of foster homes that have been opened to insure that even the most elder of dogs is given an opportunity to find a forever home. The families that open their homes to foster are compassionate individuals and without their help, Seniors Rock would not be what it is today. Seniors Rock is an organization that does not discriminate and bottom line, saves lives.
If you and your family are interested in becoming a Seniors Rock foster home, please complete our foster care application.
We look forward to sharing this adventure, and the adventure of the seniors dogs that come to stay with all of you! If you are interested in joining our group, contact us at firstname.lastname@example.com


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As part of Pope Francis' pastoral reforms, all 44 senior members of the Roman Curia, or governing body, must take turns hearing confession at a church near the Vatican.
There is even speculation that Francis himself could hear confessions at the Church of the Santo Spirito in Sassia, just outside the Vatican walls, where his bishops and cardinals have been directed to perform the sacrament of penance and reconciliation.
"I think it's likely the pope will discreetly hear confessions at some point," said Giacomo Galeazzi, a veteran Vatican watcher from Italy's La Stampa newspaper. "The pope has long been an advocate of the pastoral aspects of the ministry and now the Curia will as well."
Galeazzi and others said the change, announced Sunday, is part of a wider reform of the Vatican bureaucracy under Francis that includes the appointment of Archbishop Pietro Parolin as secretary of state. The two share a similar approach with an emphasis on humility.
The Curia, which has a powerful and central governing power at the Vatican, is seeing its role change.
"The pope doesn't want bureaucrats," Galeazzi said. "He wants pastors."
The selection of the Church of the Santo Spirito in Sassia as the location for the confessions is not a coincidence: The church is dedicated to the Divine Mercy devotion of Faustina Kowalska, a Polish nun who was named a saint in 2000 by Pope John Paul II.
The centerpiece of the devotion, according to Robert Moynihan, founder of Inside the Vatican Magazine, is the belief that God's mercy and love are always available for human beings even if they are not deserving of that love.
Eric J. Lyman writes for Religion News Service. Via RNS.
Have Something to Say?
"Pope Francis Directs Curia to Hear Confessions"


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State ScholarshipsImportant State Resource LinksState Tuition
Please Donate to the Student Victim FundTeachers are assaulting students at record numbers. Many of these convicted teachers are either sentenced to No Jail time or very little jail time. Even Teachers merely accused of sexual assault are retaining their positions. Mission of the Student Victim FundUnfortunately, there is no legal requirement for schools or courts to help the students that were victimized. Oftentimes, students who were traumatized or victimized must hire expensive attorneys or either just settle for being a victim. The mission of this fund is to raise funds for victims, raise awareness of this crisis, and reward students, and parents, and others, who help expose teacher predators. Students and parents should be empowered to Take Back the Classroom!
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Rabaul, Papua New Guinea
Photos from Rabaul
Pictures of Rabaul (555)Hotel Deals in Rabaul
Videos from Rabaul
Rabaul Videos (2)Travel Blogs from Rabaul
Rabaul Travel Blogs (45)Unlucky Past - Volcanoes & Japanese Occupation.
... for the trip saying "No pay for tyre flat". Back in Rabaul we set out to walk to the Volcanological Observatory. The Rabaul region has been rocked by at least three massive volcanic eruptions in the past 100 years and this observatory collects and manages ...
Exactly half way!!!!!
... some of the old planes, etc. There are only 10 or so cruise ships a year entereing this only port area for Papua New Guinea. People were walking across the gray land from all over to see the cruise ship visitors. They were very friendly with very ...
Another a volcano!
... New Guinea until captured by the British Commonwealth during World War I, when it became the capital of the Australian mandated Territory of New Guinea until 1937. During World War II it was captured by the Japanese in 1942, and it became the main base ...
Rabual, Papua New Guinea – 1st March 2013
... left on our pillows every night! Despite the fact, we had clearly been warned not to give the children sweets as Papua New Guinea does not have a dentist in the area. During our walk we passed a flourishing market of fruit and vegetables. ...
Attractions in Rabaul
Rabaul Attractions (1)Kabaira Dive Rabaul
North Coast Road, Rabaul, Papua New Guinea
Daily dives depart at 8AM, weather allowing.


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Spencer Rahn
Year: | Sophomore |
Hometown: | Lake Forest, Ill. |
Position: | Port |
College: | Varsity |
ATHLETIC EXPERIENCE: Joined the SCU rowing team his freshman year ... attended Lake Forest High School where he played four years of baseball.
PERSONAL: Born in Omaha, Neb. ... son of Scott and Laurie Rahn ... Economics and Finance major.


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Gluten-Free Jalapeño Poppers Recipe
Delicious, no-compromise recipes for those who need to live a gluten-free lifestyle, but don't want it to taste like it.
If you have time, consider making the filling ahead of time. This allows the flavors to mingle. Be sure to allow the filling to come to room temperature before piping into peppers.
About the author: Elizabeth Barbone of GlutenFreeBaking.com joins us every Tuesday with a new gluten-free recipe. She is the author of Easy Gluten-Free Baking. and "How to Cook Gluten-Free".
Every recipe we publish is tested, tasted, and Serious Eats-approved by our staff. Never miss a recipe again by following @SeriousRecipes on Twitter!
- Yield:12 poppers
- Active time: 30 minutes
- Total time:about an hour
- 12 jalapeño peppers
- 8 ounces cream cheese, at room temperature
- 4 ounces cheddar cheese, shredded
- 3 slices cooked bacon, crumbled
- 2 scallions, white part only, chopped
- 1 cup white rice flour
- Kosher salt and freshly ground black pepper
- 2 large eggs
- 1 cup finely ground gluten-free bread crumbs
- For Frying
- 2 quarts vegetable oil
Slice peppers 3/4 of the way from end to stem. Using the handle of a spoon, remove seeds and ribs under cool running water. Take care not to split peppers. It's a good idea to wear gloves during this step. And be sure to avoid touching face and eyes.
In small bowl, cream together cream cheese, cheddar, bacon, and scallions. Fit pastry bag with #12 round top or cut medium opening in disposable bag. Fill pastry bag. Pipe filling into peppers. If any filling oozes out of the peppers, wipe it away with a paper towel.
Freeze peppers for 10 minutes. Line up three pie pans or rimmed plates on your counter. On the first, place the white rice flour and 1/2 teaspoon salt 1/4 teaspoon freshly ground black pepper. Stir with a fork to combine. On the next plate, whisk together eggs. On the last plate, combine bread crumbs and 1/2 teaspoon salt, and 3/4 teaspoon pepper. Stir to combine.
One at time, roll peppers in white rice flour, coating completely. Then roll in whisked eggs and bread crumbs. Return peppers to eggs and then, finally, to bread crumbs. Be sure there are no bare spots on the peppers.
Place peppers on large plate. Return to freezer for 10 minutes. In heavy bottomed Dutch oven, heat oil to 375°F. Two or three at time, fry peppers until golden brown, about three minutes. Transfer to a paper towel-lined plate and season with salt. Allow to cool a few minutes before serving. Filling will be hot.


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Milwaukee County seeks to expand Family Care program to 5 more counties
Milwaukee County is poised to expand its role operating state Family Care services for older residents and those with disabilities into five additional counties.
The expansion plan, which has won initial state approval, would put Milwaukee County's program into competition with a private firm already serving clients in Waukesha, Washington, Walworth, Ozaukee and Sheboygan counties.
The proposed 2013 growth follows the Milwaukee County Family Care program's entry into Kenosha and Racine counties this year.
Growing to a regional provider of care services will help ensure the Milwaukee County program survives and thrives in a more competitive environment, said Maria Ledger, director of the Milwaukee County program.
"We want to make sure we are sustainable and have a large enough footprint," Ledger said.
A larger service area means continued growth and would allow Milwaukee County to spread its administrative costs over more clients, said James Hodson, chief financial officer for the county Family Care program.
The county is what the state calls a Family Care "care management organization," meaning it provides program administration but hires private firms to deliver services to frail seniors and people with disabilities. Support services aimed at keeping people in their homes rather than institutional care can include personal care, transportation, medical supplies and other help.
The expansion push won the endorsement of two County Board committees last week, but some supervisors expressed concerns about whether the move made financial sense, might result in lower quality services or was an improper role of government.
With an evolving state Family Care program that's tilted more toward private providers, Milwaukee County has become the last governmental provider in Wisconsin, Ledger said.
"Why is county government aspiring to compete in this type of marketplace and do so with the intention of keeping the private business sector out?" said Supervisor Deanna Alexander. She called the proposed expansion unnecessary.
Adding the five nearby counties won't result in a massive surge of clients because another care management organization - Community Care Inc. - already operates in those counties, Ledger said. Community Care is a private, nonprofit firm based in Milwaukee.
Hodson said Milwaukee County expects growth of about 3% next year - about 240 new clients on top of Milwaukee County's 7,950. About half of the new clients would come from the five new counties and the rest from Milwaukee County.
That would mirror growth this year, which included the addition of new clients in Racine and Kenosha counties. By 2015, nearly 600 new clients would be added from the five new counties, according to an estimate by Hodson.
Revenue for the program would increase about $13 million next year to $294 million, if the expansion wins all the necessary approvals. The program is financed through state and federal aid and without any local property tax money.
Ledger said quality concerns wouldn't be an issue. A client survey done this year by the county showed the majority of clients - about 90% - were happy with the quality and timeliness of their Family Care services.
Concerns raised
Supervisor Patricia Jursik was among the doubters about the proposed expansion.
The state might make things tougher for Milwaukee County with the expansion by shrinking its payment rate for clients, Jursik said. Milwaukee County gets $2,748 per month for each client it serves this year - some $700 less than Community Care. The rates are based on the particular client mix each care management firm has, with higher payments for clients with greater needs.
The state has not yet issued its 2013 payment rate to Milwaukee County.
"My prediction: It's going to get leaner and leaner for the providers" as the state tries to create efficiencies in the program, Jursik said. "They could suffer a loss very quickly."
The proposed expansion also raises governance questions about how Milwaukee County elected officials can represent client concerns from outside the county, she said.
Ledger said the expansion would require very few additional county employees.
If the County Board approves the expansion, Milwaukee County would provide information about its Family Care program to resource centers in the surrounding counties to help potential clients choose which care management organization to use.
The board takes up the issue Thursday.


text: On the night before an old friend's wedding, three frisky bridesmaids go searching for a little fun but find much more than they bargained for. With lovely Becky (Rebel Wilson) set to marry her handsome sweetheart, Dale (Hayes MacArthur), the remaining members of her high school clique reunite for one last bachelorette bacchanal in the Big Apple. Regan (Kirsten Dunst) is an overachieving, über-Maid of Honor who's secretly smarting over the fact that she's not the first to marry, while Gena (Lizzy Caplan) is a whip-smart sarcastic who's actually a closet romantic, and Katie (Isla Fisher) is a ditzy beauty who loves the good life. But when Becky insists on keeping the bachelorette party tame, the women proceed with an after-hours celebration of their own. Things get very wild very quickly, sending the unholy trinity careening across Manhattan with a torn wedding dress in tow, bum-rushing a drycleaner's, charming their way into a shuttered tailor's, and crashing Dale's bachelor party. It's there that Regan meets her match in white-collar hedonist Trevor (James Marsden), Katie gets pursued by former classmate, Joe (Kyle Bornheimer) and Gena finds herself drawn to old flame Clyde (Adam Scott). Will the girls get through the night alive? Can they fix the dress, be there for Becky, and get to the ceremony on time? Time is ticking away, but the bachelorettes are only getting started in what proves to be a life changing weekend they will never forget.


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start is the best part rest is very easy. still a enjoyable climb.
Love this climb. nice moves some difficult pulls but some sweet moves.
Sweet Climb Really Enjoyable.
got up 2 bolts. Not strong enough to get to next bolt, work in progress
Nice easy climb, flaky rock near the top. Nice placements up top for easy top roping.


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Home › Forums › Gear Forums › Make Your Own Gear › Laminating Nylon to Nanoseeum mesh to make a pullout?? Need advice
Oct 31, 2011 at 5:07 pm #1281371
Hi, I am repairing a net tent that had some pull outs ripped out. I want to patch the ripped netting with a MYOG reinforced pullout. Ideally, the pullout will look similar to the type of pullouts you see on the side of MLD duomids. Please see the picture below to understand what I'm getting at.
My question is, what kind of fabric would work best for this circular style pullout? I'm thinking something along the lines of 210d nylon, or maybe even cuben fiber.
Unfortunately, I don't have hysol, or access to a hysol dispensing gun, and don't want to drop the $ for such a simple repair. Do you think seamgrip would provide a strong enough bond to laminate the nylon or cubic fiber to each other (with nanoseemesh partially sandwiched between the 2 circular pieces of fabric?
Thanks dudes and gals!
Oct 31, 2011 at 5:30 pm #1797204The pullouts probably ripped out because whatever reinforcement patches there were, were too small to spread the force over a large enough area. Ideally, the manufacturer would have strategically run a seam in the netting through that location.
So it is a matter of sewing on larger reinforcement patches, with stiches at both the outer edges and further toward the center of the patch. Circular patches look nice, but for me, I would just sew on a hemmed rectangular patch with the conventional box and cross-bar X stitch, because I am lazy.
Know nothing about bonding netting. The ordinary urethane glues, like Elmer's are pretty good for many materials, even though not Hysol. Because ordinary urethane glues foam and bubble when drying, am planning to test some GE silicone glue on cuben, but haven't got to it yet. Wouldn't do anything without testing first for strength of the bond with some scrap materials. A stiff and inflexible bond will limit the ability of the patch to distribute force, which is not what you want.
Don't think you need 210 D patches. Anything way stronger than the netting is overkill.
Won't try to add to the already excellent contributions on this site about bonding and sewing cuban reinforcement patches.
Oct 31, 2011 at 7:37 pm #1797250I personally would just sew it, but if you don't have access to a machine or know how to sew, just try some of the GE silicon glue mentioned above. While I have never tested it on netting, it would be worth a shot at only like $3 a tube.
Oct 31, 2011 at 7:58 pm #1797262Wouldn't it be easy to glue a pullout to mesh by simply sandwiching it between two layers of glueable material?
Oct 31, 2011 at 8:16 pm #1797277Thanks for the insights everyone. Good to know a square and X stitching should suffice.
Anne, that's similar to my original intent. I was hoping to stitch (as opposed to gluing b/c I think stitching ensures strength) the tieout loop to the outside of the circular piece of fabric, and gluing that circular fabric to another circular piece, with the torn netting sandwiched between the fabric circles. I figured the circle would distribute the force across a greater surface area. If I were to simply sandwich the tieout in between 2 pieces of fabric, and just glue it all together, I worry the "sandwich" won't hold–room for error with so many pieces relying on glue to hold it all together, and not as easy to maintain the surfaces together during the adhesion process with the tie out loop bulging between/under the fabric pieces. Maybe I'm just paranoid :D
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HTC Shrinks The One (M8) To Produce The One mini 2 Smartphone
It has a 4.5" 720p HD display, Sense 6 laid atop Android 4.4 (KitKat), a 5MP front-facing camera, and the same rigid, premium exterior that we've come to expect from its larger brother. In fact, it'll be available in the same hues (Gunmetal Gray, Glacial Silver, and Amber Gold) as the M8, and will start shipping to EMEA and Asia in June. Beyond that, HTC says that you'll have to wait for wider availability and pricing details.
While the exterior remains quite familiar, the interior is changing somewhat. Gone is the UltraPixel camera of the M8, and in is a 13MP rear sensor. The power comes from a 1.2GHz quad-core Snapdragon 400, NFC capabilities, a microSD card slot, and a 2100mAh battery. The One mini 2 loses the IR blaster, Duo camera, and Motion Luanch gestures that the M8 has, but we're led to believe that these cuts will also translate into a lower, more affordable price.
The M8 was a great handset, and HTC is hoping to appeal to those who want a smaller, perhaps less pricey version of that phone. For what it's worth, it feels like the right corners were cut, with nothing too core left out of this new sibling.


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Document Type
Master of Science (MS)
First Advisor's Name
Yong Cai
First Advisor's Committee Title
Committee Chair
Second Advisor's Name
Yuan Liu
Third Advisor's Name
John Berry
Everglades, metal pollution
Date of Defense
Concentrations of 18 metals, including toxic metals (As, Cd, Cr, Ni and Pb) and essential metals (Al, Ba, Be, Co, Cu, Fe, Li, Mg, Mn, K, Sr, V and Zn) in various compartments (sediment, floc, and periphyton) were measured in the Florida Everglades to (i) establish the spatial distribution pattern of the metals in the Everglades and (ii) quantify the major sources of the 18 metals present in the Everglades. The highest mean concentrations of all metals analyzed in the Everglades were detected in soil, followed by floc and periphyton. Most metals exhibited random spatial distribution patterns. Risk assessment using Sediment Quality Guidelines (SQGs) concluded that all toxic metals (Cd, Cr, Pb, Ni, Cu, Zn and As) exhibited average concentrations that were well below FL guidelines as well as other domestic and international guidelines. On the basis of the current study, the Everglades can be considered a pristine environment.
Recommended Citation
Duan, Zhiwei, "The Distribution of Toxic and Essential Metals in the Florida Everglades" (2012). FIU Electronic Theses and Dissertations. 684.