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Re: ACP terminus bolt
i got my pocket chronograph in the mail a couple of days ago and tested my gun today. i have a velocity thumb adjuster installed on the mr2 for easy adjustment. with the ACP bolt i was shooting around 120-140 (adjuster's lowest setting). when i cranked the adjuster all the way up, i get around 140-155 (adjuster's highest setting). i tried the stock bolt and i was shooting 140-150 (adjuster's lowest setting) and then 160-190 (adjuster's highest setting).
so i think i messed up my ACP bolt by using too much oil and cleaning it with alcohol . so now im just using the stock bolt from now on. i wish i knew oil and alcohol can mess up a derin bolt when i bought the ACP terminus .
MR2 -trinity feedneck -haloB (v35, rip and 2 9v battery mod) -AK47 barrel -(crappy) trinity AK47 mag expansion chamber (took off, because it leaked too much) -ACP terminus bolt (took off, because i broke it and it shoots low fps) -MRseries flux wraparound grips |
Re: ACP terminus bolt
Technically, oil and all that is not what's wrong with bolts that tend to swell. It's the material they're made of. If it swells chances are the one that made it cheaped out and made it with a material that contains some form of nylon. I got that straight from my bud Dave who is a partnered owner of New Designz. It is easy to tell the differences in bolts made by New Designz and others made with the cheap nylon material. The nylon material is soft. So soft you can prolly dig your fingernail into it. You cannot do that with the NdZ bolts. The delrin is strong and has a hard texture to it -
KUSA Old School Alumni #4939 Registered: 6/26/02 Posts: 14,000+ before the old mothership went down Jealousy is the tribute mediocrity pays to genius while feeling alone apposed to smiling adversaries.... |
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Magnificent attention to detail throughout this custom built Spanish dream home. 15-foot ceilings welcome you into this approx. 6,000 square foot stunner with 5 gracious bedrooms, office, 5½-bathroom, over-sized cook's kitchen, family room, and step down living room. Special is an understatement to describe this authentic Spanish villa. Hardwood floors throughout, original Spanish features, floating sinks, and arched doorways create a luxurious ambiance. Inviting backyard boasts pool, Jacuzzi, waterfall treatments, built-in barbecue, fire pit/socializing area, and exotic succulents and palms. Perfect for entertaining. A must see!

subset: commoncrawl


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What housing slump?
Don't get him wrong. Neal Manowitz, who as director of marketing for Sony Electronics' consumer systems and applications division runs the company's sales in the new-home market, certainly empathizes with builders as they struggle through this downturn. But his business continues to grow.
Granted, much of that growth is in the so-called "retro" market, in which A/V systems and home theaters are being added to existing homes. Still, Manowitz estimates that A/V and home-automation gear is now going into some 15 percent of the new-home market, most of it at the uppermost end of the product lines. It is because of this, he suspects, that business has kept up during the downturn. "We're a little bit protected," he says. "Consumer appetite for HD and A/V has not diminished."
Sony, Manowitz says, continues to do most of its business in the new-home space through its dealers, who are subcontractors to builders. The direct-to-builder market has not really developed beyond a handful of companies, and Manowitz does not expect it will for "some time to come." He does, however, talk to builders regularly and says that the No. 1 reason why they choose to offer home entertainment and control systems in their homes "is to help sell the home. 'Show me a system that can help me move the inventory I have,'" is a common response, according to Manowitz.
"Throughout the downturn, we haven't seen the percentage of homes that have this technology going down," he says.
That's probably a good thing for Sony since, at its annual dealer show in Las Vegas in late February, it unveiled a new, high-end A/V rack system that will readily integrate Control4's home control systems for lighting, security, HVAC, and more with its entertainment system. This isn't entry-level stuff, or perhaps even move-up, given that the system, installed, can cost anywhere from $40,000 to $85,000, depending on its robustness. Subprime this ain't.
Dubbed the NHC-130C, the system includes a 7.1-channel, high-definition home theater for the living, media, or home theater room, plus HD video distribution and multi-room music capability for up to 12 additional zones. It has a 400-disc DVD/CD changer with a management system, a 160 gigabyte music server, a Blu-Ray Disc player, an AM/FM/XM/Sirius radio tuner, three auxiliary inputs for gaming systems or a Macintosh or PC or whatever–it can even handle an iPod.
Onto that rack system can be hung anything that is controllable via Control4 technology. That includes lighting, security systems, HVAC, and other goodies like that system that turns on the lawn sprinklers that make life in the 21st century feel, well, like life in the 21st century. It is all done via an easy hookup of modules and keypads that control the various systems using Cat 5 Ethernet, the Zigbee wireless standard, or speaker-level wire.
The integration means checking in on the security system from any video screen in the house, or changing the temperature in the viewing room to a cool 65 degrees for the showing of "Snow Dogs."
The best part is the ease of installation. The entire system was designed, according to Manowitz, "to squeeze out the cost and time needed for installation. It is very close to plug-and-play for the installer."
Now, that doesn't mean a builder can have a laborer, or group thereof, do it. But it does mean the system should go in without a hitch, and should it need tweaking in the future, it won't require the likes of Stephen Hawking.
Add to this in-wall-and-ceiling speakers from Sony's Sposato line, and the customer will be getting a knock-your-socks-off complete home control and entertainment system that will stand up against those that cost four or five times as much.
"What we are hearing from the builders is to keep things simple," says Manowitz. "But bundling all these things together, we can give them a great value.
Now, if only we can get this downturn over with.


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The Indian Stories of Francis William Bain (b. 1863, d. 1940) were published early in the 20th century. They purport to be translations of unidentified manuscripts. However, these books are not directly derived from Hindu texts or traditions. Bain was eventually unveiled as a writer of orientalist fantasies, but by that time he had a loyal readership who could care less. He continued to press on with the series until there were thirteen volumes. This is thus a harmless literary hoax on a par with Bilitis. Which is not to say that these books don't have their charm, particularly if you like early fantasy writers, such as William Morris or Lord Dunsany. Just don't use them as sources for information about Hindu mythology.
We are in the process of preparing etexts of all of these books. However, there is no particular schedule for completing them. The volumes in this series are as follows:
This is a quiet place in cyberspace devoted to religious tolerance and scholarship Non-public domain contents of this site not otherwise copyrighted are © copyright 2010, John Bruno Hare, All Rights Reserved. See Site copyrights, Terms of Service for more information. Index | FAQ | Contact | Search | Buy Disk Open Source for the Human Soul


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If you value a vibrant community on a pristine beach, then you just might want to live in Deerfield Beach in Broward County, Florida. Deerfield Beach's shining centerpiece is a "Blue Wave" beach, a designation from the Clean Beach Council. A mile stretch of beach is lifeguarded by a certified ocean rescue team.
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The 2010 census data places the population of Deerfield Beach at 75,018. Average household size is 2.02, with average family size being 2.72. The city's total area is 14.9 square miles, and within its city limits, it has some fascinating points of interest. These include the arboretum and pier, Quiet Waters Park, Deerfield Island Park, and the Deerfield Beach Historical Society.
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Can Vendrell Cava, Penedès, Spain ($25, Organic)
Made from three indigenous grape varieties in Spain's northeastern Catalonia district, this Cava is made in the same method as Champagne, but comes in at a fraction of the price. The second fermentation that occurs inside the bottle imparts a yeasty richness to the finished wine that makes it the perfect partner to a broad range of foods, including cold meats, appetizers, pastas and picnic fare.
Read on for more on wines and spirits, including a look at a Japanese whiskey as well as what happens when regular and reserve wines are tasted head-to-head.


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works like a charm.
Yes you need a developers account to legally obtain the IPSW files.
For future reference you should search for a post that discusses the topic you have in mind and post there instead, but to answer your question, Siri is an iPhone 4S exclusive feature.
Maybe someone can help. I've downloaded the latest redsn0w (0.9.9b2) and my iPhone 4 is running iOS 5 GM currently. Every time I "Select IPSW" and point it towards iOS Beta 7 for iPhone 4 GSM it says it isn't recognized. I've redownloaded iOS Beta 7 3 times now from 3 different places.. Any ideas?
Make sure you downloaded the right firmware GSM or CDMA or for another device if it is right...
You can try too if not tried yet, put your iPhone in DFU and try to update from iTunes.


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SAIC (www.saic.com)
Full Time
Virginia Beach
United States
Instructor Tier II (Virginia Beach, VA) (Job Number:419080)
Job Description:
The Training and Simulation Service Line, in support of the Navy and Marine Corps Customer Group, currently has contingent career opportunities for Training Analyst?s in support the Center for Surface Combat Systems (CSCS) in Virginia Beach, VA.
Training Analyst?s will support training courses in support of initial, replacement and conversion training for existing and new courses instructed across the CSCS domain in accordance with the prescribed training schedule in Corporate Enterprise Training Activity Resource System (CeTARS), Surface Force Exercise Manual (SFEM), Ballistic Missile Defense Qualification (BMDQ), Anti-Submarine Warfare Qualification (ASWQ) Program or the Waterfront Course Catalog. Training locations may also include shipyards and Fleet Surface Ships.
We are looking for Training Analysts/Instructors that are subject matter experts with one or more of the following surface combat systems; Auxiliary Systems (AUX), Aegis AN/SPY-1 radar, Command, Control, Computers, Communication, and Intelligence (C4I), Anti-Submarine Warfare Systems (ASW), Ship Self Defense System (SSDS), Navigation systems, Aegis Computer Network Technician (ACNT), Close-In Weapon System (CIWS), Embedded Training System (ETS), Vertical Launch System (VLS), and the Surface Vessel Torpedo Tube (SVTT).
The Training Analyst and Instructor develops, directs, plans and evaluates these courses and related training activities to meet the particular learning objectives for each combat system. Must be current on all latest Fleet guidance depicting combat systems current doctrine, and tactics, techniques, procedures (TTP). Assignments may include:
- Custom course development, development of criteria for evaluating the effectiveness of course objectives, and evaluation and learning assessments.
- Create new course content, training materials, visual aids and documentation to support a variety of instructional formats such as lecture, lab exercises, field training, computer-based training (CBT), and/or web-based training (WBT).
- Develop exam materials and may be responsible for testing and qualitative evaluation of participant's attainment of learning objectives.
- Instruct in various CSCS courses in combat system(s) as qualified, and provide mobile team training support on the waterfront or onboard ships as directed by the customer.
- Provide Operational Plan (OPLAN)/Concept of Operations Plan (CONPLAN) level team training in an environment utilizing complex warfare area scenarios targeting Navy Tactical Task (NTA)/Navy Mission Essential Task List (NMETL) critical weapons employment skills.
- Provide unscheduled emergent corrective maintenance to continue execution of training being instructed at CSCS training facilities.
- Provide training to current surface combat systems to include Air Defense Systems Integrator (ADSI) and Link Monitoring and Management Tools (LMMT).
- Liaison between CSCS and the IAMD, ASW, Anti-Surface Warfare (ASUW), and Mine Warfare (MIW) warfare leads, appropriate fleet activities, and the Naval Surface and Mine Warfighting Development Center (NSMWDC) in matters of tactics, doctrine development and instruction.
Typical Education:
- Bachelors and three (3) years of more of related experience
- Masters and one year of related experience.
- Three (3) years of experience with the required system as either a maintenance technician supervisor or operator supervisor with responsibility for teaching the applicable system or function task to others in a journeyman level training environment.
- Of the three years, one (1) year of experience as an instructor in a Navy Training Environment, to include curriculum maintenance, writing learning objectives, preparing test items, evaluating instructional materials and the results of instruction and counseling students on academic learning problems.
SAIC Overview:SAIC is a leading provider of technical, engineering and enterprise information technology services to the U.S. government. Our 13,000 employees deliver systems engineering and information technology offerings for large, complex government programs, as well as a broad range of higher-end, differentiated technology services. The company is headquartered in McLean, Va. For more information, visit www.saic.com.
EOE AA M/F/Vet/Disability
Job Posting: May 24, 2016, 9:00:00 AM
Primary Location: United States-VA-VIRGINIA BEACH
Clearance Level Must Currently Possess: Secret
Clearance Level Must Be Able to Obtain: Secret
Potential for Teleworking: No
Travel: None
Shift: Day Job
Schedule: Full-time
To apply for this job, contact:


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Alternative Title:
"Emil und die Detektive"
Learn about this topic in these articles:
discussed in biography
...tragic novel
Fabian (1931). His children's books are notable for their humour and respect for the child's moral seriousness. The most famous of these,
Emil und die Detektive (1929;
Emil and the Detectives), was several times dramatized and filmed. Prevented by the Nazis from publishing in Germany (1933–45), he printed his works in Switzerland. After the war,...
place in children's literature
...low ones.
Der Kampf der Tertia (1927; "The Third-Form Struggle"), by Wilhelm Speyer, was Germany's excellent contribution to the genre of the school story. Erich Kästner's
Emil and the Detectives (1929) ranked not only as a work of art, presenting city boys with humour and sympathy, but as an immediate classic in an entirely new field, the juvenile detective story...


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35-44 year old woman treated with Breast Augmentation
35 year old female unhappy with the lack of volume to her breasts. She underwent breast augmentation with 535cc silicone implants placed under the muscle with an incision in the crease under the breast.
By uploading this photo, Ankur Mehta, MD has agreed with RealSelf.com policy that they've secured proper patient consent.


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I've needed to get the directory a program was running several times. I've used it to determine where configuration files could be found. I've used it for determining where images should be stored/loaded. I've also had to write it from scratch several times :( . I'm submitting it here so hopefully someone else doesn't have to figure it out themselves.
I've found that using _getcwd isn't accurate whenever the user is allowed to use the file dialogs to open or save files. If they move to a different directory in the file dialogs, the current working directory is changed as well
CString GetProgramDir() { CString RtnVal; char FileName[MAX_PATH]; GetModuleFileName(AfxGetInstanceHandle(), FileName, MAX_PATH); RtnVal = FileName; RtnVal = RtnVal.Left(RtnVal.ReverseFind('\\')); return RtnVal; }
It's not much, but I've found it helpful and hope that someone else will as well.
This article, along with any associated source code and files, is licensed under The Code Project Open License (CPOL)
hModule [in] Handle to the module whose path is being requested. If this parameter is NULL, GetModuleFileName retrieves the path for the current module.
General News Suggestion Question Bug Answer Joke Praise Rant Admin
Use Ctrl+Left/Right to switch messages, Ctrl+Up/Down to switch threads, Ctrl+Shift+Left/Right to switch pages.


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Master of Science in Education -
Teaching Methodology Concentration
After completing our Post Baccalaureate Teacher Certification program, you have the option of enrolling in our Master of Science in Education degree program with a concentration in Teaching Methodology.
The MS.Ed. in Teaching Methodology is available only to UNE graduate Teacher Certification Students. This is a 30 credit master's degree program encompassing 15 graduate credits from the Teacher Certification Program (TCP) and an additional 15 credits that have been designated to satisfy Department and State of Maine requirements for certification in areas of elementary education (K-8), secondary education (7-12), or art education (K-12). The remaining 15 credits are completed after you receive initial certification and are designed to provide in-depth study in differentiation, classroom management and research.


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Equipment and inventory formerly owned by Green Field Energy Services Inc. in Lafayette is being sold by a Boston firm after it received sale order approval from a Federal Bankruptcy Court.
Green Field Energy Services filed for Chapter 11 bankruptcy protection on Oct. 27.
Its assets, including well services and hydraulic fracturing equipment valued at more than $250 million, will be marketed by Gordon Brothers Group. The equipment, in Louisiana and Pennsylvania, was acquired by Gordon Brothers' commercial and industrial division.
"Gordon Brothers Group provided an ideal solution for Green Field and our creditors as they took sole control of a very large and diverse portfolio of equipment involved in this transaction," said Rick Fontova, president of Green Field Energy Services.


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byAndrew R. Hickey on
Company Name: Custora
The Lowdown: Custora offers on-demand e-marketing and predictive analysis applications that businesses use to identify customers and keep them engaged. The applications help improve customer retention by analyzing transaction patterns to figure out how customers behave and predict their buying behavior as much as two years out -- what Custora calls "customer lifetime value."
The system can help, say, an online retailer re-engage with a customer that's been idle using targeted promotions. It can also help e-tailers and subscription services allocate ad spending. Custora, founded in 2010 and appearing live in late February, touts itself as a low-cost alternative to expensive e-marketing and predictive analysis apps. Backed by startup funder Y Combinator, Custora has already lined up about a dozen customers including Foodzie, GetSatisfaction, Kobo and Scribd.
CRN's third annual Channel Madness Tournament of Chiefs is under way! Choose your favorites:


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There are creatively placed web advertisements everywhere you look on the internet, and certain companies seem to always be at or near the top of the search engine results page (SERP). Driving these companies is a thriving industry of Search Engine Optimization (SEO) professionals, but not all SEO is equal, and not everyone is professional. In fact, some of them use techniques to reach top positions that can do more harm than good to an online business. This is due to the way search engines rank web sites.
To grossly oversimplify it, all search engines use one form or another of proprietary logic to distinguish good sites from bad sites. While there are a great many factors that determine whether a site is good or bad, the most basic metric every search engine uses is a count of the number of links or references to and from a particular site. The more often a website is linked to from relevant and quality sites, the higher it will rank in search indexes. Conversely, links to or from low quality sites can lower that rank. When all factors are calculated, the site is then compared to other sites for the same search terms, resulting in its final position, or SERP.
This makes reaching and holding the number position extremely competitive, and potentially very lucrative. Many companies spend huge sums of money and sometimes resort to unethical methods to manipulate SERP so their site ranks in the top. Because of this, every search engine provider constantly tweaks its system that identifies quality content from questionable content, and good sites from bad. Some of what works today won't work tomorrow, and in some cases can actually damage a company's ranking. A classic example is BMW, who admitted to manipulating search results, and as a result was temporarily blacklisted by Google. Despite this and numerous other high-profile examples, many SEO companies continue developing new and more creative ways to trick search engines. To protect your company, it is important to understand what separates good SEO from bad SEO.
Put simply, SEO is a lot like the old "Spy vs. Spy" cartoon. Black hat is bad, white hat is good, and they use nearly identical tactics. Fortunately, differentiating between them is very straightforward. If the online action or advertisement your SEO company is suggesting provides value to the end user, then it is most likely white hat, and will provide long term benefits to your SERP. If the answer is no, then it is most likely black hat, and will ultimately damage your business, even if it provides short-term gains.
For example, the top white hat public relations company in terms of volume is PR Web, holding the top spots for blogs, number of releases, site traffic, and social media. A sample release for a custom writing service can be seen here, and demonstrates white hat methodologies. The article is well written, logically structured, and provides value to the reader in the form of information about the topic. This is what search engines thrive on.
Conversely, black hat sites often link to completely unrelated services, consist of spam content, or make off-topic posts that are unrelated and irrelevant to a blog or site's subject matter. Many times they also include masked links that trick users into visiting other sites. In the worst cases they even plagiarize and recycle content to trick search engines into believing it is original (this is known as content spinning, and should never be used). These methods all detract from the user experience, and can do significant damage to brand reputation.
Based on how easy it is to differentiate between the two, it would seem logical for companies to only use white hat methodologies. Unfortunately, the actual line between black hat and white hat is not equally enforced across all search engines or sites. Many times sites are not immediately rewarded or punished for their online actions. This allows black hat sites to regularly reach the top spots in search results, while white hat sites often tend to lag behind.
Business managers who focus on visible results but don't understand SEO may elect to adopt black hat methodologies to achieve immediate and visible results. They rarely understand that they are creating a cycle of short-term gain, followed by long-term setback. Instead they see an action and expenditure of resources directly translating to results. Later, when they are required to change tactics to reach a top rank again, once more they see an action and expenditure of resources that generates results. Few realize that they are just spinning their wheels until it is too late and they have caused lasting damage to their SERP.
Complicating matters, some companies using white hat methodologies may decide they are wasting their efforts, as a seemingly endless stream of black hat sites always manage outrank them, but that is where most people fail to fully understand the why behind white hat SEO.
Put simply, if search engine algorithms are constantly adapting to black hat SEO, and black hat methods are constantly evolving to manipulate search results, then effective black hat techniques will always put their company in the number one position, but no black hat company will keep the top position for an extended period. In fact, with search engines blacklisting sites for months or more, it means that any time the top search rank position is occupied by a black hat company, it is guaranteed to be replaced by a different company in a relatively short time. In the internet world, where almost everything is constantly changing and evolving, consistently being second in SERP means that your site will always be there, unlike the black hat sites that will come and go.
Since marketing and advertising is built on impressions, always being number two is far better than occasionally being number one. Just like in car racing, never missing a race can win the season, even if you never take first place. Making sure your business follows white hat practices will keep you in the race, and maintain a high SERP position.
Image Credits:
Feature Image: 'SEO Punishment' Article Image: '31st Annual Freihofer's Run for Women' Article Image: 'Racing Down the Runway' Found On: flickrcc.net


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Kusar Prasad Ka Bhoot News
Neetu Chandra birthday special: 5 hottest avatars of Neetu Chandra!
As the bombshell from Bihar celebrates her birthday today, Bollywoodlife brings you five of her hottest avatars
Born on June 20,1984 at the capital of Bihar, Neetu Chandra has came a long way away from home to make it big in cine field. The hottie started modelling at a young age and appeared in several TV commercials. Not many know but the starlet has two black belts in Taekwondo and represented India in World Taekwondo championships in Hong Kong in 1997.Click here to read more -


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The Witch and the Hundred Knight: Revival Edition is an action game where the player controls the Hundred Knight. Players can enjoy this refreshing action game with simple controls. Tactical Conversion: The Hundred Knight can equip up to five weapons simultaneously and chain them together for a maximum 5-hit combo. This system is called Tactical Conversion! The further into the combo you go, the stronger each attack becomes. Create your own unique attack patterns by equipping all manner of weapon sets. Giga Calories and Consuming: Hundred Knight will grow hungry the longer it is away from Metalllia. Its hunger level is measure in Giga Calories (Gcals). Once this number falls to zero, Hundred Knight will forcibly be returned home. If you want to quickly replenish your Gcals, consume a weakened enemy. Attack Elements: There are three attack elements recognized in Medea: Slash, Blunt and Magic. Inflict greater damage by using the element that enemy is weak against. It is important to know your opponents and your weapons. Slash - Common in Swords and Lances. Many slash weapons deal pure damage to enemies. Blunt - Common in Spears and Hammers. Due to its stunning properties, blunt weapons can stop enemies dead in their tracks. Magic - Common in Staves. Can cause status ailments such as poison and sleeps. Facets: Hundred Knights abilities and appearance change depending on the equipped facet. HP/RES and weapon proficiencies shift based on the facet used, so switch it up depending on the map and the enemies being faced. Wander Knight - Hundred Knights original facet. It has an average compatibility with all equipment, making it well rounded. Power Fortress - A tough-looking facet meant for high HP and physical attack/ defense. It is strong against slash and blunt attacks, but is quite weak against magic. Marginal Gaze - This facet is strong with staves and spears, and is good at dealing magic damage. However, it prevents you from gaining karma. Tochka: Tochka skills embody and release Hundred Knights remaining powers. Tochka represents the power of 99 knights. Summon Tochka allies as traveling companions, or as a trump card in a tough battle. Type 1 Mini Knight - An independent-type Tochka. You can summon up to eight to a time. Once summoned they will fight on their own. These cute things will follow Hundred Knight around Type 8 Time Bomb - A bomb-type Tochka. Its detonation is a time-based and can destroy magic walls. Its blast will also inflict damage to anyone within range, including Hundred Knight, so be careful when handling this hot potato. Type 10 Diallo - An arrow-type Tochka. You can summon up to three at a time. It can be used as a long-range projectile or to operate certain devices. Use the lock-on function to guide the arrows toward targets. Battle Techniques: Mystical Dodge - Dodge attacks to the very last moment to activate Mystical Dodge, which lets Hundred Knight become invincible and slows time temporarily. Use it to run away to safety or perform a super strong attack on an enemy. Extra Chain - Defeat an enemy in one hit to activate Extra Chain. Once activated, Hundred Knight will instantly move to the nearest enemy and inflict its next attack. The longer the chain, the stronger the attacks will become. Chaos Revelation - Use Chaos Revelation to release Hundred Knights locked potential. However, using Chaos Revelation will consume Gcals at a rapid pace and will not stop until all Gcals are depleted. This is a special action to use against the mightiest of opponents. Psysical Revelation - Gather grade points to increase stats or replenish Gcals. The effects of grade points will reset upon exiting a map, so use them freely! Tower of illusion: An exciting, new dungeon from The Witch and the Hundred Knight: Revival Edition . Enter the Tower of Illusion by offering a weapon. The enemies and dropped items in the tower are determined by the strength of the weapon. Offer strong weapons to fight strong enemies! Summon Metallia - In the Tower of Illusion, the player can obtain Concentrated Mana . By gathering enough Concentrated Mana, the player will be able to summon Metallia for a certain amount of time. Regular and Charge Attack - Summon a sword and perform up to a 3-combo attack. By holding down the button, the player will be able to perform a charge attack. Magic Attack (Five Way Spell) - Cast spells that burst into five directions, destroying all enemies in your path. Magic Attack (Mega Magic) - Perform a lightning spell that strikes down enemies in a large aread. Magic Attack (Vacuum Enemy) - Suck enemies into one space. Use this to defeat all enemies at once! Alchemy: In the tower of Illusion, Alchemy can be used to upgrade weapons by gathering catalysts . Depending on the type of catalyst, you can not only increase your ATK, DEF and HP, but much more!
Check stock and price


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Top Items:
Allen Stern / CenterNetworks:
FriendFeed Follower Patterns Exposed: How Jason, Mike, Loic & Robert Get So Many Followers So Quickly (video) — Over the past 24 hours, Jason Calacanis, Robert Scoble, Loic Lemeur and Michael Arrington have all asked essentially the same question. They are all wondering how they got so many followers on FriendFeed so quickly.
Jason Calacanis / The Jason Calacanis Weblog:
Twitter's milkshake meet FriendFeed's straw — For the past two weeks or so I've focused the majority of my "short messaging/blogging" from Twitter to a new service called FriendFeed. FriendFeed is very similar in relation to twitter in that both systems are designed to help you share quick messages.
Michael Arrington / TechCrunch:
Friendfeed v. Twitter: Half The Followers In Five Months — Twitter is still far larger than its much younger competitor Friendfeed in aggregate terms. But an interesting trend is developing - many longtime Twitter users are noticing that the number of followers they have on Friendfeed is growing far more rapidly than on Twitter.
Incremental Blogger, The Viral Garden, Sean Percival's Blog, Oliver Thylmann's Thoughts and Dembot
Robert Scoble / Scobleizer:
The "Participation Premium" — Data: Mike Arrington …
The "Participation Premium" — Data: Mike Arrington …
Global Neighbourhoods
Charles Jade / Infinite Loop:
The disruptive potential of GPS on the iPhone 3G — A recent survey showed nearly half of respondents rated GPS as a deciding factor in favoring an iPhone 3G, which should be good news for makers of GPS software and services. Or not. Forbes has an interesting article that suggests …
MacRumors iPhone Blog
NBC UNIVERSAL, BAIN CAPITAL AND THE BLACKSTONE GROUP SIGN AGREEMENT TO ACQUIRE THE WEATHER CHANNEL PROPERTIES FROM LANDMARK COMMUNICATIONS — NBC Universal, Bain Capital and The Blackstone Group today announced the signing of a definitive agreement to acquire The Weather Channel properties from Landmark Communications.
Silicon Alley Insider
Rafat Ali / paidContent.org:
Deal Done: Weather Channel Sold To NBCU and Bain/Blackstone Combo — The Weather Channel deal is finally done, and announced on a lazy, bright and clear July 4th weekend Sunday: Landmark Communications has agreed to sell The Weather Channel to a consortium of NBC Universal (NYSE: GE) …
Phone Arena:
LG Chocolate 3 to be released July 14th — Beginning on July 14th, Verizon will introduce its new music-centric device, the Chocolate 3. Unlike the first two LG Chocolate phones that were sliders (VX8500, VX8550), the new VX8560 model will be a clamshell avaliable initially in Black and Light Blue.
Ross Mayfield / Ross Mayfield's Weblog:
Service and the Fifty Percent Rule — Next time you go into an Apple store, notice that 50% of the space is for retail sales and 50% for service and support. I overheard this weekend that it is the most profitable arrangement in the history of retail. — True or not, it is curiously obvious …
Lou Dolinar / LinuxInsider:
What's Holding OpenOffice Back? — Why doesn't free trump expensive? Every Microsoft product has a free, open source counterpart created by dedicated programmers who loathe everything the company stands for. The free stuff is darn good. Yet companies and individuals continue to buy billions of dollars worth of Microsoft products.
Dave Caolo / The Unofficial Apple Weblog:
Flickr Find: Macintosh on Nintendo DS — While browsing Flickr this afternoon, we came across a shot of a Nintendo DS running Macintosh System 6 in emulation on reader Ken Fager's Flickr stream. Of course, we contacted him to ask how he did it. Here's what he had to say.
Arn / MacRumors:
Customer Backlash on iPhone Rate Plans, Launch Approaches — As international pricing for the iPhone has been trickling out, customers in some countries are particularly unhappy about their rate plans for the upcoming iPhone launch. — Sweden's TeliaSonera rate plans, which started at 299 kr/month …
Anne Eisenberg / New York Times:
Novelties: Electronic Papyrus: The Digital Book, Unfurled — New technologies are developing that make displays flexible, foldable or even as rollable as papyrus, so that large screens can be unfurled from small containers.


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2014/2015 Mercedes-Benz MLC – new images
New image of the Mercedes MLC that allows an idea of the appearance of the future German crossover.
The five-door car will compete with the Bavarian car BMW X6 and get motors ranging from 265 to 544 hp
Externally, the new model will be similar to CLS, and settle down in her salon chair anatomy.
It is expected that four-wheel drive Mercedes-Benz MLC will cost in Europe about 45 000 euros.


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NEW YORK (MarketWatch) — U.S. stock futures pointed to a slightly upbeat open on Wall Street on Tuesday, as the earnings season continued at full speed, including results from Sprint, Coach and Merck, among others.
In economic news, home prices were nearly unchanged in February. Investors await consumer-confidence data after the market open.
Futures for the Dow Jones Industrial Average US:DJM4 climbed 45 points, or 0.3%, to 16,442, while those for the S&P 500 index US:SPM4 gained 4.5 points, or 0.2%, to 1,870.50. Futures for the Nasdaq 100 index US:NDM4 put on 7 points, or 0.2%, to 3,5478.
In Asia, Obama had to thread a needle
The WSJ's Andrew Browne discusses how President Obama did in his mission to calm fears of abandonment from U.S. allies in Asia without provoking China.
The advances came after a choppy trading day on Monday, when most benchmarks swung wildly between gains and losses, but settled higher.
In Tuesday's trade, stock futures tracked European markets higher, where an easing in geopolitical tensions between Russia and the West helped send bourses higher. Late Monday, Moscow assured Washington that it won't invade Ukraine, while reports said Russian troops had left the Ukrainian border and returned to their base. Asia markets closed mixed.
Traders also waited for the latest corporate news and fresh macroeconomic data for clues on whether to push the markets higher.
Among data highlights, the Conference Board's consumer-confidence index is expected to reflect the hope that better days lie ahead when the April report is released at 10 a.m. Eastern Time. Economists surveyed by MarketWatch expect the Conference Board's consumer-confidence index to climb to 83.3 in April from 82.3 in March.
If the estimates are right, such an increase in confidence would boost the index to its highest level since November 2007 — one month before the Great Recession started.
U.S. home prices were nearly unchanged in February, after slumping 0.1% in each month since November, according to S&P/Case-Shiller's 20-city composite index released Tuesday. After seasonal adjustments, home prices in February rose 0.8%.
In corporate news, several prominent companies reported early Tuesday. Sprint Corp. S, +0.48% shares rose more than 3% in premarket action after the company posted a loss of 4 cents a share, against forecasts for a loss of 9 cents, in the first quarter.
Merck & Co. MRK, +0.24% rose 0.8% premarket after it reported adjusted earnings of 88 cents a share, against forecasts for 79 cents a share, in the first quarter. Coach Inc. COH, +2.20% shares fell 3.6% after the luxury-goods retailer reported weak North American sales.
Shares of Archer Daniels Midland Co. ADM, +0.82% dropped 2% after the company's first-quarter profit and sales missed analysts' forecasts.
Shares of Amicus Therapeutics Inc. FOLD, -1.87% soared 25% in premarket trading after the company announced positive data in a study of a drug to treat patients with Fabry disease.
After the closing bell, Twitter Inc. TWTR, -0.33% is projected to report a loss of 3 cents a share in the first quarter, according to a consensus survey by FactSet. "We believe Twitter will continue to benefit from its mobile-centric offering," Youssef Squali at Cantor Fitzgerald said in a report. "Similar to Facebook, high mobile contribution should power overall growth."
EBay EBAY, +0.30% is forecast to post first-quarter earnings of 67 cents a share. Analysts at Susquehanna on Monday raised the stock's target price to $61 a share from $59.
In more premarket moves, Gogo Inc. GOGO, +1.21% shares slid 17% after AT&T Inc. T, +0.17% said Monday it would launch in-flight, high-speed Internet service on airlines, competing with Gogo.
Herbalife Ltd. HLF, +0.14% could also be active after the nutrition-products firm late Monday said first-quarter earnings fell to 74 cents a share from $1.14 a share a year ago. The board also decided to terminate its dividend and instead will use the funds to buy back shares in the second quarter.
ABB Ltd.'s ABB, +0.30% ABBN, +0.96% U.S. listing slid 7% ahead of the open after the Zurich-based power-and-technology group reported an 18% drop in first-quarter profit.
Nokia Oyj's FI:NOK1V NOK, -1.10% U.S.-listed shares rallied 5% in premarket trade after the Finnish telecom-equipment firm said it will spend about 5 billion euros ($6.9 billion) on dividends, share buybacks and debt reduction.
In other financial markets, most metals US:GCM4 declined, while oil prices CLM4, +0.17% advanced. The dollar fell against most major currencies.
More must-reads from MarketWatch:
Bull market won't die until a recession hits: RBC


text: On Wednesday, Union Taxi, a new driver-owned cab company, turned to state regulators to complain that two other companies were given exclusive access to a waiting area at Cherry Creek Shopping Center. "We are simply asking the commission to rigorously apply the logic that Colorado's taxi regulation scheme requires---no discrimination, kickbacks, or special preferences for any company and equal treatment of all consumers," stated Ray Gifford, an attorney and partner at Kamlet Reichert, LLP, the firm representing Union Taxi (via the Denver Business Journal). But forget the complaint. The mall has already relented. Orange-and-blue Union cabs will be allowed to join Metro and Yellow taxis at the cab stand, as will purple-and-white Freedom Cab taxis. "We've had feedback from the community voicing concerns about our decision," Cherry Creek general manager Nick LeMasters tells The Denver Post. "We recognize that the policy may have been shortsighted, and we have reconsidered our position." Last month, Cherry Creek created a sponsorship deal with Metro and Yellow to pay lease space in exchange for the right to pick up shoppers.


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Iniesta: Sometimes things are said without thinking or without meaning to cause hurt
Barcelona midfielder, Andres Iniesta has played down the public rift between the club's economic vice-president, Javier Faus and four-time Ballon d'Or winner, Leo Messi over a potential seventh contract renewal for the Argentine in the past five years.
In a recent interview with Spanish television station, La Sexta's, 'Jugones' programme, Iniesta spoke about the issue and stressed that Messi has justified the renewed contracts because of what he means and gives to the club.
"Sometimes things are said without thinking or without meaning to cause hurt. Messi is a fundamentalplayer. He is for me, and for the club too.
"I'd love for Messi to win the Ballon d'Or, everyone as Barca would feel like part of the award."
Iniesta went on to discuss his own contract renewal, which will keep him at the Camp Nou until 2018 when he is the ripe ol' age of 34.
"I went to the signing with my parents and my daughter. I thought about a lot and I was the proudest person in the world. My dream is to be able to end my career at Barça."


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Staff at the Jisc's Regional Support Centre Wales have been doing the final rounds of our friends and colleagues in the colleges, universities and skills providers across Wales, before we wind up as 'RSC Wales'. In the New Year, 'Jisc Wales' will be born – so please watch your mailboxes and the Jisc website for news of that. The last few meetings have been an opportunity for reflecting on the key issues which are exercising minds right now, and internet safety has been one of the themes which has emerged several times. In view of this, I thought that now would be a good time to bring together a few of the resources which were created in the course of the #SID2014 activities.
Students and staff at Coleg Cambria supporting Safer Internet Day 2014.
Providers set up a range of activities which engaged learners with some key questions which elicited their attitudes to the internet – both what they value and appreciate, and those things which concern them or make them anxious. The activities ranged from classroom discussion, to the use of 'pop-up photo booths' and some fully fledged video content. This has served at least two purposes: firstly, encouraging learners to reflect on their own roles as participants in the internet; secondly, giving the providers more information with which to work on internet safety. For me, one key message emerged: user attitudes and skills are as important in keeping people safe online as are specific security policies and technologies (important as those are).
Providers have already begun to use these outcomes to inform both their planning of their events for #SID2015, and are also incorporating them into current classroom sessions on a range of topics, helping to embed digital literacies into the wider curriculum.
Some examples are included in the 'Livebinder' which I have set up here: http://www.livebinders.com/edit?id=1597372#anchor .I think that the quality of these contributions from learners speaks for itself. Enjoy!
Find out more about Safer Internet Day here: http://www.saferinternetday.org/web/guest;jsessionid=FE6CFD76670B0447F14F330A3A29CA3E , and take a look at Jisc's own resources here: http://www.jisc.ac.uk/internet-safety. Those who attended the recent Wales Learning Technology Forum in Llandrindod Wells may like to follow up some of the references on internet safety which came up in that discussion, here: https://pinboard.in/u:paulbrichardson/t:%2523SID2014/


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text:
Study to Determine the Effect of Repeated Administration of Diltiazem on the Pharmacokinetics of Darapladib (Sb-480848).
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- How to Read a Study Record
Darapladib (SB-480848) is a novel, selective, orally active inhibitor of lipoprotein associated phospholipase A2 (Lp-PLA2) currently under clinical development by GlaxoSmithKline as a potential anti-atherosclerosis agent for reduction of major adverse cardiovascular (CV) events in patient populations with chronic coronary heart disease and after an acute coronary syndrome.
This study will determine the effect of repeated administration of diltiazem on the pharmacokinetics of a repeated administration of darapladib. A drug interaction study with a moderate CYP3A4 inhibitor is warranted to provide guidance to prescribing physicians.
Condition | Intervention | Phase |
Atherosclerosis |
Drug: Darapladib Drug: Diltiazem |
Phase 1 |
Study Type: | Interventional |
Study Design: | Intervention Model: Single Group Assignment Masking: Open Label Primary Purpose: Treatment |
Official Title: | An Open-Label, Three Period, Single Sequence Study To Determine The Effect Of Repeat Oral Dosing Of Diltiazem On The Pharmacokinetics Of Repeat Oral Dosing Of Darapladib (SB-480848). |
- AUC(0-24h) of darapladib [ Time Frame: Up to 32 days. (PK samples will be collected on Days 8, 9, 26 and 27 at predose. Day 10 and Day 28 predose and at 0.5, 1, 2, 3, 4, 6, 9, 12, 18, 24, 32, 48, 72, and 96 hours post-dose) ]The area under the concentrations-time curve (AUC0-24) from the time of administration of darapladib up to 24 h after administration.
- Cmax of darapladib [ Time Frame: Up to 32 days. (PK samples will be collected on Days 8, 9, 26 and 27 at predose. Day 10 and Day 28 predose and at 0.5, 1, 2, 3, 4, 6, 9, 12, 18, 24, 32, 48, 72, and 96 hours post-dose) ]The maximum concentration (Cmax) was obtained directly from the measured concentration-time curves.
- Number of subjects with adverse event (AE). [ Time Frame: Up to 70 days. ]AE's will be collected from the start of study treatment to the last follow up.
- 12-Lead electrocardiogram (ECG) assessment as a measure of safety and tolerability [ Time Frame: Up to 42 days. (Screening Day 32 and Follow up [Day 38 to 42]). ]Single 12-lead ECGs will be obtained after the subject has been in a supine position for at least 10 minutes at each timepoint during the study using an ECG machine that automatically calculates the heart rate and measures PR, QRS, QT, and QTcF intervals.
- Vital signs assessment as a measure of safety and tolerability [ Time Frame: Up to 42 days (Screening, Day -1, 15, 16, 22, 28, 32 and Follow up [Day 38 to 42]). ]Systolic and diastolic blood pressure and pulse rate measurements will be recorded after the subject has been resting in a semi-supine or supine position for at least 10 minutes.
- Safety laboratory tests assessment as a measure of safety and tolerability [ Time Frame: Up to 42 days (Screening, Day -1, 15, 32 and Follow up [Day 38 to 42]). ]Hematology, clinical chemistry, urinalysis were assessed.
- Tmax and t1/2 of darapladib. [ Time Frame: Up to 32 days (PK samples will be collected on Days 8, 9, 26 and 27 at predose. Day 10 and Day 28 predose and at 0.5, 1, 2, 3, 4, 6, 9, 12, 18, 24, 32, 48, 72, and 96 hours post-dose. ]Tmax is defined as the time required reaching the maximum concentration of the drug in the plasma after its administration. t1/2 is defined as the time taken to reach half the concentration of the drug after administration.
Enrollment: | 36 |
Study Start Date: | May 2013 |
Study Completion Date: | September 2013 |
Primary Completion Date: | September 2013 (Final data collection date for primary outcome measure) |
Arms | Assigned Interventions |
Experimental: Darapladib+Diltizem Arm
Each subject will receive darapladib EC tablet 160 mg once daily for 10 days followed by darapladib EC tablet 160 mg once daily + diltiazem 240mg once daily for 14 days and then diltiazem 240mg once daily alone for three days
Drug: Darapladib
Enteric coated, free base (micronized) white round tablet, 160mg, Oral/repeat dose/10 days (Treatment Period 1), 14 days (Treatment Period 2)
Drug: Diltiazem
Extended release, Blue capsule imprinted with cardizem CD and 240mg on one end, 240 mg, Oral/repeat dose/17 days
Ages Eligible for Study: | 18 Years to 65 Years (Adult) |
Sexes Eligible for Study: | All |
Accepts Healthy Volunteers: | Yes |
Inclusion Criteria:
- Male or female aged between 18 and 65 years of age inclusive, at the time of signing the informed consent.
- Healthy as determined by a responsible and experienced physician, based on a medical evaluation including medical history, physical examination, laboratory tests and ECG.
- A subject with an alanine aminotransferase (ALT), aspartate aminotransferase (AST), alkaline phosphatase or bilirubin laboratory result outside the reference range may be included only if both the Investigator and the GSK Medical Monitor agree and document that the finding is unlikely to introduce additional risk factors and will not interfere with the study procedures.
- BMI within the range 19-37 kilogram per square meter (kg/m2) (inclusive).
- A female subject is eligible to participate if she is of non-childbearing potential defined as pre-menopausal females with a documented tubal ligation or hysterectomy [for this definition, "documented" refers to the outcome of the investigator's/designee's review of the subject's medical history for study eligibility, as obtained via a verbal interview with the subject or from the subject's medical records]; or postmenopausal defined as 12 months of spontaneous amenorrhea [in questionable cases a blood sample with simultaneous follicle stimulating hormone (FSH) > 40 milli-international units per milliliter (MlU/ml) and estradiol < 40 picogram/milliliter [(pg/ml) (<147 pmol/L) is confirmatory].
- A female subject is eligible to participate if she is of Child-bearing potential and is abstinent or agrees to use one of the contraception methods for an appropriate period of time (as determined by the product label or investigator) prior to the start of dosing to sufficiently minimize the risk of pregnancy at that point. Female subjects must agree to use contraception until the final follow-up visit.
- A female subject is eligible to participate if she is of Child-bearing potential and has only same-sex partners, when this is her preferred and usual lifestyle.
- Capable of giving written informed consent, which includes compliance with the requirements and restrictions listed in the consent form
- Single QT duration corrected for heart rate by Fridericia's formula (QTcF) < 450 Millisecond (msec)
Exclusion Criteria:
- A subject will not be eligible for inclusion in this study if any of the following criteria apply:
Criteria Based Upon Medical Histories
- Current or chronic history of liver disease, or known hepatic or biliary abnormalities (with the exception of Gilbert's syndrome or asymptomatic gallstones).
- History of regular alcohol consumption within 6 months of the study defined as an average weekly intake of >14 drinks for males or >7 drinks for females. One drink is equivalent to 12 g of alcohol: 12 ounces (360 ml) of beer, 5 ounces (150 ml) of wine or 1.5 ounces (45 ml) of 80 proof distilled spirits.
- History of sensitivity to heparin or heparin-induced thrombocytopenia.
- History of sensitivity to any of the study medications, including diltiazem, or components thereof or a history of drug or other allergy that, in the opinion of the investigator or GSK Medical Monitor, contraindicates their participation.
- Any contraindications for diltiazem administration.
- Any condition that, in the opinion of the investigator, presents undue risk from the study medications, including diltiazem, or procedures.
- Requiring the use of oral or injectable strong Cytochrome P450 (CYP3) A4 inhibitors or use of other CYP3A4 inhibitor/inducers within 14 days prior to dosing.
- History of anaphylaxis, anaphylactoid (resembling anaphylaxis) reactions
- Clinical criteria for diagnosing anaphylaxis or severe allergic response. Criteria Based Upon Diagnostic Assessments
- A positive pre-study Hepatitis B surface antigen or positive Hepatitis C antibody result within 3 months of screening
- A positive pre-study drug/alcohol screen.
- A positive test for human immunodeficiency virus (HIV) antibody.
- Pregnant females as determined by positive human chorionic gonadotropin (hCG) test at screening or prior to dosing.
Other Criteria
- Where participation in the study would result in donation of blood or blood products in excess of 500 mL within a 56 day period.
- Lactating females.
- The subject has participated in a clinical trial and has received an investigational product within the following time period prior to the first dosing day in the current study: 30 days, 5 half-lives or twice the duration of the biological effect of the investigational product (whichever is longer).
- Exposure to more than four new chemical entities within 12 months prior to the first dosing day.
- Unable to refrain from the use of prescription or non-prescription drugs, including vitamins, herbal and dietary supplements (including St John's Wort) within 7 days (or 14 days if the drug is a potential enzyme inducer) or 5 half-lives (whichever is longer) prior to the first dose of study medication, unless in the opinion of the Investigator and GSK Medical Monitor the medication will not interfere with the study procedures or compromise subject safety.
- Unwillingness or inability to follow the procedures outlines in the protocol.
- Subject is mentally or legally incapacitated.
- Consumption of grapefruit or grapefruit juice within 7 days prior to the first dose of study medication.
Please refer to this study by its ClinicalTrials.gov identifier: NCT01852565
United States, Maryland | |
GSK Investigational Site | |
Baltimore, Maryland, United States, 21225 |
Study Director: | GSK Clinical Trials | GlaxoSmithKline |
Responsible Party: | GlaxoSmithKline |
ClinicalTrials.gov Identifier: | NCT01852565 History of Changes |
Other Study ID Numbers: |
115679 |
Study First Received: | May 9, 2013 |
Last Updated: | October 4, 2013 |
Keywords provided by GlaxoSmithKline:
CYP3A4 Lp-PLA2 Atherosclerosis healthy volunteer Drug interaction |
Additional relevant MeSH terms:
Atherosclerosis Arteriosclerosis Arterial Occlusive Diseases Vascular Diseases Cardiovascular Diseases Darapladib Diltiazem |
Phospholipase A2 Inhibitors Enzyme Inhibitors Molecular Mechanisms of Pharmacological Action Antihypertensive Agents Calcium Channel Blockers Membrane Transport Modulators Vasodilator Agents |
ClinicalTrials.gov processed this record on March 27, 2017


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It's not every day you can be taken back to your childhood on the way to work! Commuters who struggle blearily into London's busiest railway terminus on Monday morning (19 October) will think they are still dreaming.
In the middle of the main concourse at Liverpool Street Station will be a real child's bedroom complete with a brass bed, cloud wallpaper, side table, lamp, books, soft toys - and a lot of people in pyjamas.
As part of The Children's Society's National Bedtime Reading Month, a magical childhood scene has been created to highlight the importance of parents, and especially fathers, reading to their children.
A poll of 1,001 adults compiled by NfP Synergy for The Children's Society found that half of dads read every night to their children. The National Bedtime Reading Month campaign highlights the need for dads to read and talk about books with their children, in order to demonstrate the importance of reading and learning about books. When dads engage with their children's education, they significantly boost their children's IQ, their performance at school and their chances of having healthy, successful lives.
Representatives from The Children's Society will be donning their nightwear to spread this message to commuters and some young children will be dropping in to enjoy the fun. Entertainment will be provided for the event by a host of TV, pop and stage stars who have recorded a version of Roald Dahl's classic bedtime story, Fantastic Mr Fox. Footage of Blur front man Damon Albarn, TV presenters Jeff Brazier and Eamonn Holmes and West End star Brian Conley reading the story will be shown on a large screen on the 'bedroom' wall throughout the day.
The bedroom will be staged at the Broadgate exit on the main concourse of Liverpool Street Station. Commuters on their way to or from work can come along and show their support for the work of The Children's Society. Photographers wishing to come along should contact The Children's Society media office on 020 7841 4422, firstname.lastname@example.com, and meet at 10am at Liverpool Street Station, outside Monsoon.
National Bedtime Reading Month coincides with the launch of 20th Century Fox's latest animated movie, Fantastic Mr Fox, who have generously supported the event. The event is also backed by the award winning Mr Gum books by Andy Stanton, which won the inaugural Roald Dahl Funny Prize in 2009.
Notes to Editors
The Children's Society is a leading children's charity committed to making childhood better for all children in the UK.
- 87% of girls reached the required standard of reading at the end of primary school, compared with 81% of boys. (DCSF: National Curriculum Assessments at Key Stage 1 in England, 2008.)
- National Bedtime Reading Month is being launched in association with 20th Century Fox and its new animated movie Fantastic Mr Fox, and the award-winning Mr Gum children's book series by Andy Stanton.
- Fantastic Mr Fox is Directed by Wes Anderson and stars Meryl Streep, George Clooney and Bill Murray. It tells the story of angry farmers who, tired of sharing their chickens with a sly fox, look to get rid of their opponent and his family.
- Mr Gum is published by Egmont, the UK's top specialist children's publisher with three award-winning divisions selling more than 25 million books and 12 million magazines each year: Egmont Magazines; Egmont Press (fiction and picture books); and Egmont Publishing (licensed character books). The Mr Gum books are written by author Andy Stanton, winner of the inaugural Roald Dahl Funny Prize and the top selling World Book Day author of 2009.
- Celebrity dads can be seen reading Roald Dahl's classic story, Fantastic Mr Fox on our YouTube channel, http://www.youtube.com/user/childrenssociety.
- For more information contact The Children's Society's Media Team, Tel: 020 7841 4422.


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CASE 2013: Lunch with Leaders
From August 18, 2013 00:00 until August 18, 2013 23:00
This exciting opportunity is being offered to RAS members who have Graduated in the Last Decade (GOLD) and current student members. Allowing for networking with established and celebrate leaders within the automation and robotics community, it is a valuable experience.Advanced registration for the Lunch with Leaders is required ($5 USD) and available now. Space is limited.


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This section contains 280 words (approx. 1 page at 300 words per page) |
By any standard—and surely these days books for the 14-year-old upwards ought to stand up as adult fare—[Jazz Country] is an excellent novel. Not only does Nat Hentoff show with great perception the development of one boy's understanding of other people, but without any strain, without recourse to either hip jargon or learned explanations, he opens for the uninitiated the significance of the world of jazz….
Tom is a nice guy, making good grades at school and with the kind of calm, sympathetic parents every teenager must long to have. The narrative comes clearly and straightforwardly from his lips. "Your life has been too easy for you to be making it as a jazz musician", the Negro bass player in the great Moses Godfrey's band tells him after hearing his talented but heartless trumpet playing. "And too white", adds his militant wife, Mary. By the end...
This section contains 280 words (approx. 1 page at 300 words per page) |


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Seems like everyone uses
Atlanta-based Exploit Prevention Labs says criminals have been using Google's
Here's how the potential crime was supposed to work: Searches for business- and car-related words produced ads next to search results for legitimate pages like Cars.com and the Better Business Bureau's Web site. But when users clicked on those ads, Exploit Prevention says they were first redirected to a Russian site called SmartTracker.org. That site would download a program onto the user's machine before sending them on to their destination site. When users later visited one of a hundred major banking sites the software was designed to target, the program would spy on them using a "post-logger," a program that inserts fake entry fields into Web sites and records passwords.
Google said in a statement Thursday that it had removed the fraudulent ads and is "continuing to monitor the situation closely." The company also said it is "committed to ensuring the safety and security of our users and our advertisers," and is working to remove malware infected pages from both its ad network and its search results.
Google's advertising program, which accounted for nearly all of the company's $10.6 billion in revenue last year, allows anyone to bid online for search terms related to their business. When users search for those terms, the business' ad appears beside search results. Because the Adwords buying process works with little human supervision, says Exploit Prevention's Chief Technology Office Roger Thompson, the system is ripe for abuse. "Google is in a tough position," says Thompson. "They make it easy for anyone to purchase Adwords. That's their fundamental business model. But that makes it difficult for Google to filter out the bad guys."
Exploit Prevention analyzes the Web browsing of about 50,000 users of its software, probing links on Web pages to find viruses or malware. For about two weeks starting April 10, the company detected around 30 instances of the Russian site's fraudulent link appearing beside Google Adwords. Thompson believes the problem is likely to continue.
"They'll change the name, move to another Web site and buy more Adwords," Thompson says. "We can be sure that they'll be back."


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There are crazy cat ladies and then there's Lisa, a 43-year-old Detroit resident who is addicted to eating her cat's fur.
Lisa's preferred hairball delivery system is via manual grooming, meaning she likes to lick the fur directly off of the cat herself. (When that's not an option she simply picks up stray fur from around her apartment and, bon appetite, down it goes.)
DVR the Season Premiere of "My Strange Addiction"
Lisa says chewing and swallowing the hair, which apparently tastes like "cotton balls," helps her unwind and bond with her furry friend. Unfortunately, Lisa's habit, which will be featured on the Feb. 13 premiere of TLC's "My Strange Addiction," has gotten out of hand. She cannot go two hours without a fix and is now eating three quarter-sized hairballs per day. Will she be able to kick her hair-eating habit? Tune in to the fourth season premiere of "My Strange Addiction" on Wednesday, Feb. 13 at 10/9c on TLC to find out.
See Lisa's "Strange Addiction" Below:


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New Jersey is taking steps to elevate teaching, but must still do more. The state has reformed tenure significantly and adopted better educator evaluations, though student growth is not yet a predominant criterion. Effectiveness is not tied to placement or salary decisions, and districts are required to base layoff decisions on seniority, putting effective educators at risk. New Jersey must also do more to empower parents. The state must make information to parents regarding teacher and school performance more accessible. New Jersey should create an opportunity scholarship program for low-income students and expand availability of quality choices by strengthening charter accountability for authorizers and increasing access to comparable resources and facilities for public charter schools. New Jersey should also allow mayors to take control in low-performing districts. Finally, the state should no longer lock teachers into the existing pension system and should offer a more attractive, portable retirement option.
Monday, January 7, 2013
Quote of the Day
Students First, Michelle Rhee's group, has just issued State Policy Reports. This is from New Jersey's (presumably value-added) evaluation:
2 comments:
- An Educational Enthusiast said...
Attracting a high-quality workforce will require a competitive retirement plan...
New Jersey should move to a portable employer-sponsored retirement plan
and permit public charter schools to opt out of the plan.
http://edref.3cdn.net/3cfde6555b1638252a_irm6vlx5e.pdf - January 8, 2013 at 12:45 PM
- kallikak said...
New Jersey rates a "D" while Louisiana and Florida earn "B"s?!
Are you kidding? I'll take the NAEP scores any time over Ms. Rhee's self-serving nonsense.
P.S. Will we ever see a proper investigation and analysis of the D.C. test-score erasure scandal?? - January 9, 2013 at 11:13 AM
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January 4, 2007 SonicWALL, Inc. (NASDAQ: SNWL), a leading provider of network, Web, email security and backup and recovery solutions, has deployed early protection against a rapidly proliferating variant of the Nuwar worm, which is spreading via emails containing seasonal greetings in the subject line. The rate of infection has picked up rapidly, and seems set to become one of the biggest threat outbreaks of the year.
Once a computer is infected, it looks for open mail proxies and begins sending email to infect other computers. The mass-mailing worm is already moving quickly across the Internet, installing multiple codes on victims' computers and then protecting them with rootkit. Users of SonicWALL's Unified Threat Management technology, which protects against viruses, Trojans, worms and other threats and vulnerabilities, automatically received updated signatures designed to repel the Nuwar worm.
The worm spreads via email, in most cases with the subject line "Happy New Year!" containing attachments typically named as one of the following: "Greeting Card.exe", "Greeting Postcard.exe", "Postcard.exe", "greeting card.exe", "greeting postcard.exe", or "postcard.exe". Upon execution, the worm attempts to disable running Anti-Virus processes and drops a Tibs Trojan on the infected computer system. Subsequently, the worm tries to download additional malicious code from the remote website.
During propagation, the worm sends a copy of itself by using its own SMTP engine to the email addresses found in the address book of the infected PC. In some instances, the worm sends a malformed executable copy (i.e. containing an incorrect executable header) that could be considered harmless and can simply be treated as SPAM email.
Very early samples of this variation on the Nuwar worm were first discovered in the wild on December 29th, 2006. On December 30th 2006 SonicWALL issued the following signatures designed to protect against this threat:
About SonicWALL, Inc.
Founded in 1991, SonicWALL, Inc. designs, develops and manufactures comprehensive network security, email security, secure remote access, and backup and recovery solutions. SonicWALL is headquartered in Sunnyvale, California and trades on the NASDAQ under the symbol SNWL. For more information, contact SonicWALL at +1 (408) 745-9600 or visit the company web site at http://www.sonicwall.com/.


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The University of Georgia football team is looking forward to a little rest and the 2013 season.
The Bulldog football team will miss the seniors who led UGA to 12 wins in 2012.
A couple of underclassmen showed their is still plenty of talent on the UGA roster that will be back this fall.
Cornerback Damian Swann intercepted two passes against Nebraska.
Camilla's Justin Scott-Wesley got a big boost of confidence with two big catches including one on the drive that scored the eventual winning touchdown for the Bulldogs.
Scott-Wesley "A man tremendous confidence. We are going to come back next year. 2013 is the year of the dog.
Justin Scott-Wesley caught his first touchdown pass against Georgia Southern.
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(Photo by John Kenney/The Gazette)
Canadiens general manager Marc Bergevin expressed satisfaction with the team's season, but said there's still a lot of work to do during a press conference Monday morning in Brossard.
The Canadiens finished the season with 100 points and made a deep playoff run, making it to the Eastern Conference final.
"Overall it's a very good season. A 100-point season with the playoffs to get to the conference final is excellent," Bergevin said.
The Canadiens aren't a mature team yet, but they're a good young team, Bergevin added.
"I feel we're not a mature team," he said. "We're a good young team. Our core … they're young veterans I call them. We're moving forward. There are teams that I look around the league they're more mature. And for them you could almost say every year they're a guaranteed playoff team, but we're not there.
"Next year we go back to the same starting line with everybody else. Our first goal will be to make the playoffs. And after that … once you're in, anything is possible."
At the start of next season there will be a whole bunch of teams fighting to make the playoffs, Bergevin added.
"That's the way we are sitting here today and hopefully years down the road we'll become a more mature team, but we're not there yet," he said. "But we have a lot of good things going for us."
Bergevin confirmed that forward Dale Weise suffered a concussion during Game 5 in the Eastern Conference final series against the New York Rangers.
Weise returned to the ice after going to the 'quiet room' and being cleared to return by doctors.
After the contact, the doctors evaluated the situation and the protocol was followed to the letter, said Bergevin, adding that a player can often feel concussion symptoms a day or a few days later.
"It happened the next day," Bergevin said.
"The NHL has a protocol that needs to be followed after a player is hit," he said.
"If the player said he's OK and the test says he's OK, then he's OK. Until we change that, we personally, the team, the organization is very strict on how we operate with any type of injury. Players they have a list of things they need to do before they return to play and he passed with flying colours."
The Canadiens were told Weise had a concussion the next day, Bergevin said.
"The league is working on making it as safe as possible. But that's a discussion that is ongoing with the league. We all worry about our players. But again, we can only go by what we have to deal with."
Asked what he believes the Canadiens need to address to take the next step, Bergevin simply said: "The next few weeks we're going to sit down internally with our staff. It's a little early to project what we're going to try to do … but again, overall I thought our young players learned a lot. What they learned during the last 17 playoff games is something that you cannot buy."
That learning experience included three elimination games in the playoffs against the Boston Bruins in Games 6 and 7 and the Rangers in Game 5 that the Habs won.
"What they learned in the last month and a half it's huge." Bergevin said.
When Canadiens goaltender Carey Price was injured in Game 1 of the Eastern Conference final, the Habs opted to start rookie Dustin Tokarski for the rest of the series instead of regular backup Peter Budaj.
The way Tokarski played in the regular season with the Canadiens and also during the playoffs "you see that it's a good puzzle to have–depth at all positions," Bergevin said. "And it takes nothing away from Peter Budaj, who in in my opinion is one of the best back-ups in the National Hockey League."
Asked whether defensive prospects Jarred Tinordi, Nathan Beaulieu and Greg Pateryn have to play next year in the NHL, Bergevin said: "There's no 'have to.' They probably will.
"It's going to be them that's going to make the decision for us," the GM added. "Do I want them to, sooner than later? Yes. … Hopefully they are, but that's going to be up to them. But they're really going in the right direction."
Bergevin has several key decisions looming with four unrestricted free agents and seven players who will become unrestricted free agents on July 1.
Bergevin was tight-lipped, saying he doesn't publicly discuss contracts when asked about P.K. Subban and Andrei Markov, who will become an R.F.A. and U.F.A., respectively.
"So as far P.K., Markov, (Lars) Eller – you can name them all – it's something that I'm going to be working on throughout the next weeks, the summer," Bergevin said. "I don't know how long it will take. Everything has its own time frame."
You can listen to the first part of Bergevin's press conference here:
The second part is here:
Bergevin tight-lipped about offseason plays, by The Gazette's Pat Hickey
Bergevin remains voice of calm for Habs, by The Gazette's Dave Stubbs
Deep playoff run makes exit more painful for Habs' Prust, by Dave Stubbs
The Montreal disease infects Habs fans, by Jack Todd for The Gazette
GM Bergevin has decisions to make on free agents, by Pat Hickey
Vanek says lack of chemistry hurt him with Habs, by Pat Hickey
Pacioretty says Habs aren't always treated fairly, by Pat Hickey
Coaching Canadiens comes with a price, by Gazette sports editor Stu Cowan
Price praises backup Budaj, montrealgazette.com
Photos: Youppi! in a Rangers jersey, montrealgazette.com


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BEIJING – Al-Jazeera's sole English-language reporter in China has been expelled, the pan-Arab news network said Tuesday. It's the first time since 1998 that Beijing has kicked out an accredited foreign journalist.
Melissa Chan's expulsion is seen as China's latest attempt to punish international media whose reports the authoritarian government dislikes and sees as besmirching its global image. The move "seems to be taking China's anti-media policies to a new level," Bob Dietz, the Asia coordinator for the Committee to Protect Journalists, said in a statement.
Qatar-based Al-Jazeera said in a statement that it had no choice but to close its English-language service's bureau because Chan's press credentials and visa were not extended. Chan is a U.S. citizen who worked for the network in China for five years. She had reported extensively on sensitive topics such as illegal seizures of farmland and the imprisonment of petitioners from the countryside in unofficial "black jails."
The U.S. State Department said it had followed Chen's case closely and was disappointed in the Chinese government's decision not to renew her accreditation.
"To our knowledge, she operated and reported in accordance with Chinese law, including regulations that permit foreign journalists to operate freely in China," spokesman Mark Toner told a news briefing in Washington.
Al-Jazeera said no permission to replace Chan was given and its requests for additional visas for correspondents had gone unanswered. The expulsion does not impact Al-Jazeera's Arabic-language service, which maintains several accredited journalists in its Beijing bureau.
Foreign reporters in China often experience harassment, surveillance and visa problems when government officials are angry at their reports. Over the weekend, police called in about a dozen foreign reporters, threatening to revoke their visas for allegedly breaking rules in reporting the case of blind legal activist Chen Guangcheng by entering the parking lot of the hospital where he is receiving medical care.
Al-Jazeera did not say if any reason was given for expelling Chan, who was not among the journalists called in.
Hong Lei, spokesman for the Foreign Ministry which oversees accreditation for international media, refused repeatedly at a regularly scheduled news conference Tuesday to say Chan's accreditation was not renewed.
"We stress that everybody must abide by Chinese laws and regulations and must abide by their professional ethics," Hong said.
The Foreign Correspondents' Club of China said Chinese officials accused Chan of unspecified violations and were unhappy with some of Al-Jazeera's coverage, particularly a documentary that Chan had not been involved in. The documentary, which aired in November, was about China's system of sentencing minor criminals and political prisoners to labor camp prisons.
The club issued a statement Tuesday saying it was "appalled by the decision of the Chinese government to take this action."
Al-Jazeera reported extensively on last year's Arab Spring anti-government uprisings in Tunisia, Egypt and elsewhere — events that profoundly spooked the Communist Party leadership. After calls were posted online for similar protests in China, Beijing responded with a harsh crackdown on media, lawyers, writers and government critics.
The director of news at Al-Jazeera English, Salah Negm, defended Chan and the network's coverage.
"We constantly cover the voice of the voiceless and sometimes that calls for tough news coverage from anywhere in world. We hope China appreciates the integrity of our news coverage and our journalism," Negm said in the network's statement.
A German reporter and a Japanese reporter were the last foreign journalists expelled from China, in late 1998.
Chan has left China and will be returning to California, where she will be taking up a Knight Fellowship at Stanford University.
China had pledged to relax restrictions on foreign journalists as part of its hosting of the 2008 Summer Olympics, but changes have been minor and conditions have in some ways grown even more hostile.
Foreign reporters working in China must obtain a press card from the Foreign Ministry before they can apply for a visa. Those documents must be renewed at the end of each year, and the ministry sometimes delays issuing a press card for reporters it is unhappy with.
In Chan's case, the correspondents' club, which is not recognized by the Chinese government, said this year the ministry issued her a two-month press card rather than the standard one-year accreditation, then extended that for one month before refusing to give her another extension, forcing her to leave the country.
Issuing of visas for journalists can take months and some applications receive no response at all. In February, the Washington Post's ombudsman wrote that one of the newspaper's two China correspondents, Andrew Higgins, has not been given a permanent visa to report from inside China since he was hired in 2009.
Higgins, when working for the British newspaper The Independent, was expelled by Beijing in 1991 after reporting on a confidential document about secret arrests in China's Inner Mongolia region.
At the same time, Beijing is attempting to spread its own pro-China take on domestic and international events with a major push into foreign-language media by state broadcaster CCTV and the official Xinhua News Agency.
Associated Press writer Matthew Pennington in Washington contributed to this report.


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Federal, state officers catch bear poachers
State and federal wildlife officers are cracking down on bear poaching in western North Carolina and eastern Georgia.
Wednesday, authorities announced a multi-agency undercover operation that's been in the works for the past four years. The investigation, which was named Operation Something Bruin, yielded 80 wildlife violators and about 980 violations stemming mostly from illegal bear hunting.
Officers with the Georgia Department of Natural Resources and the North Carolina Wildlife Resources Commission infiltrated poaching circles to document violations including bear baiting, illegal taking of bears, deer and other wildlife, illegal use of dogs, operation of illegal bear enclosures in North Carolina, and guiding hunts on national forest lands without the required permits.
They began making arrests Tuesday, although the names of those being charged have not yet been released.
Those who are convicted face possible jail time and a minimum fine of $2,000.
"Operation Something Bruin documented hundreds of wildlife violations. Today's arrests bring an immediate halt to those crimes and, we hope, will make would-be violators think twice before breaking the law..." said Col. Dale Caveny, law enforcement chief for the N.C. Wildlife Resources Commission.
U.S. Forest Service, the U.S. Fish and Wildlife Service and the National Park Service were also involved in the investigation.
According to the N.C. Wildlife Resources Commission, fewer than 10 percent of all wildlife crimes are reported. Wildlife officers ask anyone who sees what they think could be a violation to call 1-800-662-7137.
Thankful that these people are busted. They give hunters a bad name. There are ethical hunters, and then there are the hunters who have no sense in this county. You will find their hounds at the Haywood County Animal Shelter where they take them when they no longer have any use for them. Most of these hounds end up in the land fill. Don't blame the animal shelter. They do not like putting down dogs who could make good pets. Blame the irresponsible people who call themselves hunters, but just dump their dogs at the end of the season like they are a pair of old boots. Shame on them. Shame, shame, shame.
I am so happy and pleased the poachers are found out. It is a shame one can not abide the law.


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Alstroemeria 'Third Harmonic'
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Comparing Chest Images From MRI to CT in Patients With Cystic Fibrosis (CF)
- Full Text View
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- No Study Results Posted
- Disclaimer
- How to Read a Study Record
The purpose of this research is to learn more about the heart and blood vessels in the lungs of people with cystic fibrosis (CF). This study will include approximately 36 children and adults with CF and 12 children and adults without CF. The study will involve one magnetic resonance imaging (MRI) . The research also includes blood samples to look at inflammation and lung tests called spirometry and Lung Clearance Index (LCI) determined by Multiple Breath Washout test.
For the CF subjects, enrollment will be timed to coincide with routine scheduled computerized tomography (CT) or the CF subject may choose to have a CT for research purposes. The MRI will be compared to CT images of the lungs. The goal is to develop better imaging that does not use radiation.
Condition |
Cystic Fibrosis |
Study Type: | Observational |
Study Design: | Observational Model: Case Control Time Perspective: Prospective |
Official Title: | Study of Cardiac MRI to Assess Pulmonary Perfusion and Pulmonary Hemodynamics in Patients With Cystic Fibrosis Study (Pilot 3) |
- Cardiopulmonary MRI and CT [ Time Frame: Baseline (MRI and CT acquisition) ]Assess perfusion in each pulmonary segment. Segmental perfusion will be scored on a continuous scale (0=normal, 1=mild abnormality, 2=moderate abnormality, 3=severe abnormality) for each of the 18 lobar segments.
Biospecimen Retention: Samples With DNA
Estimated Enrollment: | 48 |
Study Start Date: | April 2013 |
Estimated Study Completion Date: | May 2017 |
Estimated Primary Completion Date: | November 2016 (Final data collection date for primary outcome measure) |
Groups/Cohorts |
CF Group
Cystic Fibrosis group with MRI and CT of chest
Control group
Non-CF controls will have MRI and no CT of chest
Detailed Description:
Cystic Fibrosis (CF), the most common inherited disease in Caucasians, is characterized by chronic pulmonary inflammation and progressive loss of gas exchange units that eventually results in respiratory failure. There is strong evidence that in CF abnormally low vascular perfusion carries a high risk of death independent from the presence of pulmonary hypertension. However, the evolution of pulmonary vascular disease in CF and how it might contribute to the rate of decline in lung function is not known. Knowledge remains limited to the results of old observational studies which concluded that the major causes of pulmonary vascular remodeling and hypertension in CF are hypoxic respiratory failure and destruction of lung tissue. Recent data obtained by state-of-the-art Magnetic Resonance Imaging (MRI) of the pulmonary circulation, challenges the existing paradigm. Studies demonstrate that in the absence of hypoxia, significant changes in pulmonary perfusion and in surrogate measures of vascular resistance as well as in collateral blood flow begin early in the course of CF. The newly developed therapeutics in the last decade which altered dramatically the course of patients suffering from pulmonary vascular disease provide opportunities to understand the role of pulmonary vasculature in CF lung disease.
This pilot study (Pilot 3) will assess the relationships between pulmonary perfusion, serum markers of pulmonary inflammation and vascular remodeling, and hemodynamic measures consistent with pulmonary hypertension. This study will establish MRI as a readily obtainable modality to be used in the CF population to obtain measurements of pulmonary perfusion; pulmonary arterial hemodynamic, dimension, and flow measures; and ventricular mass and function measures.
The primary goal of this study is to improve the understanding of pulmonary vascular disease in CF by examining pulmonary perfusion abnormalities and their association with markers of pulmonary inflammation and pulmonary vascular remodeling, the severity of obstructive airways disease, and pulmonary hemodynamic abnormalities in CF.
This study will include a single MRI of the pulmonary circulation on about 36 pediatric and adult patients with CF and about 12 non-CF controls. UTE (Ultrashort Echo Time) MRI will be performed without contrast. CF patients who are scheduled for clinical chest CT will be enrolled and the scheduling of the MRI will be coordinated with the clinical CT. CF subjects may also choose to enroll independent of clinical CT and choose to have a CT for research purposes only. Other study procedures include blood specimen for serum biomarkers and lung tests called spirometry and Lung Clearance Index (LCI) determined by Multiple Breath Washout test. Blood specimens will be analyzed for a panel of inflammatory markers.
Ages Eligible for Study: | 5 Years to 60 Years (Child, Adult) |
Sexes Eligible for Study: | All |
Accepts Healthy Volunteers: | No |
Sampling Method: | Non-Probability Sample |
Inclusion Criteria:
- Age 5 and older
- Diagnosis of cystic fibrosis confirmed by a prior sweat chloride evaluation of > 60 mmol/liter or by two identified CF mutations on genetic analysis; or no CF for controls
- Able to perform acceptable and repeatable spirometry per American Thoracic Society/European Respiratory Society (ATS/ERS) joint consensus criteria.
- If CF, have valid spirometry data for at least 3 years
- If under the age of 18, the patient must assent to participation in the study, and the patient's parent or guardian must be able to give written informed consent and comply with the requirements of the study protocol
- If 18 years of age or older, the patient must be able to give written informed consent and comply with the requirements of the study protocol
- Negative serum pregnancy test (for women of child bearing age)
- Able to tolerate MRI without sedation
Exclusion Criteria:
- Pregnancy (a negative serum pregnancy will be performed for all women of childbearing potential within 7 days of imaging) or lactation
- Subjects with a history of renal
- Subjects with a history of hypersensitivity to gadolinium (Magnevist)
- Contraindications specific to MRI including a history of claustrophobia, cardiac pacemaker, or other non-MRI compatible surgical implants (This includes neuro-stimulators containing electrical circuitry, or which generate electrical signals and/or have moving metal parts, and metal orthopedic pins or plates. The research coordinator and/or the MRI technologist will screen all patients using the standard checklist of medical history and safety questions used by the Radiology Department in routine clinical scans.)
- Inability to comply with study procedures
Please refer to this study by its ClinicalTrials.gov identifier: NCT01860872
Contact: Beth Decker, RN | 513-803-4325 | email@example.com | |
Contact: Beth Decker | 513-803-4325 | firstname.lastname@example.com |
United States, Ohio | |
Cincinnati Children's Hospital Medical Center | Recruiting |
Cincinnati, Ohio, United States, 45229 | |
Contact: Megan Bushman, RN 513-803-7690 email@example.com | |
Principal Investigator: John Clancy, MD |
Principal Investigator: | John Clancy, MD | Children's Hospital Medical Center, Cincinnati |
Responsible Party: | Children's Hospital Medical Center, Cincinnati |
ClinicalTrials.gov Identifier: | NCT01860872 History of Changes |
Other Study ID Numbers: |
CIN001-CF MRI 1R01HL116226-01 ( US NIH Grant/Contract Award Number ) |
Study First Received: | May 15, 2013 |
Last Updated: | July 25, 2016 |
Keywords provided by Children's Hospital Medical Center, Cincinnati:
Cystic Fibrosis Pulmonary perfusion Inflammatory markers |
MRI CT of chest Lung Clearance Index |
Additional relevant MeSH terms:
Fibrosis Cystic Fibrosis Pathologic Processes Pancreatic Diseases Digestive System Diseases |
Lung Diseases Respiratory Tract Diseases Genetic Diseases, Inborn Infant, Newborn, Diseases |
ClinicalTrials.gov processed this record on March 28, 2017