text: Ride Around In Your Own Criminal-Built DalekKevin Kelly2/01/08 5:02pmFiled to: doctor whoconsdalekeBayinmatesPrisonprisonersReplica15EditPromoteShare to KinjaToggle Conversation toolsGo to permalink The Australian government might have come up with the most brilliant prison plan ever: use hardened criminals to churn out replicas of science fiction props, and then sell them on eBay. Sadly, they aren't using the money to fund the development of robot prison guards — all proceeds are going to charity. The fools. Why not keep that dough and buy yourself a high tech lair? Advertisement The Woodford Correctional Center in Queensland, Australia has built a full-sized Dalek replica from Doctor Who that comes complete with wheels, space for an occupant, and an electronic voice changer. Granted, you have to Fred Flintstone the thing around with your feet, but it's a small price to pay. You can pedal this thing down to your local market and shout "EX TER MI NATE!" until you get arrested. Priceless.Bidding is up to $3000 bucks Australian right now, which is roughly $2700 US, although you'll have to fly down to Australia to pick the thing up, since they wont ship it outside of Oz. You might also want to check and make sure it's passenger-free when you get it, since these same inmates melted the walls at the prison with toasters in 1997 and escaped. Maybe they've incorporated that same wall-melting in the Dalek's beam weapon. Advertisement 'Doctor Who' Dalek For Sale [Comic Mix]Reply15 repliesLeave a reply


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GEOG-2213 World Regional Geography
An interpretive study of the political map of the world and some of its recent changes. Attention is focused on the role of location, physical environment, population, ethnic groups, natural resources, and technological change in the evolution of nation-states and dependent territories. This course is normally offered in the fall semester of odd numbered years.

subset: commoncrawl


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Halloween Express Store in Nashau, NH
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text: Felix Baumgartner is about to attempt the most ambitious skydive in history — watch it here (UPDATED)Robbie Gonzalez10/09/12 10:15amFiled to: This is awesomeSpaceSciencespace jumpSpace diveNasaLockheedkittingerBaumgartnerThompsonStratosRed BullJonathanClarktweetFb33EditPromoteShare to KinjaToggle Conversation toolsGo to permalink When most people skydive, they jump from an altitude between 3,000 and 15,000 feet. Today, extreme athlete Felix Baumgartner will leap from a balloon soaring 120,000 feet above sea level.AdvertisementShould Baumgartner survive the descent, he stands to shatter no fewer than four high-risk world records.UPDATE: Today's supersonic jump attempt has been aborted. See here for updates.The first three were all set by U.S. Air Force Captain Joe Kittinger, who in 1960 claimed the rights to highest skydive, highest manned balloon flight and longest human free-fall ever recorded (Kittinger spent close to 300 seconds hurtling toward the Earth with nothing but wind resistance to slow his staggering descent).AdvertisementBut it's the fourth record that is truly unprecedented. If all goes according to plan, Baumgartner will become the first person in history to achieve supersonic speeds outside of an aircraft.Baumgartner's record-smashing jump is the culmination of the Red Bull Stratos Project, which has been steadily working toward this moment for over two and a half years.We've put together an extensive backgrounder covering all the details surrounding the jump, including: the equipment that Baumgartner will be using, what to expect in the minutes leading up to (and immediately following) his leap from the edge of space, and the wealth of scientific information that we stand to glean from the project. Read it in full here, then check the live feed up top for weather updates and information on when the jump will take place. As of this posting, the earliest launch time will be 17:30 GMT (that's 13:30 EDT or 10:30 PDT for those of you in the U.S. — click here for international time zone conversions). Given that Baumgartner's trip to space will take close to three hours, that means the earliest jump-time we can expect is around 20:30 GMT/16:30 EDT/13:30 PDT.


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User:Rai Marshall
From Bulbapedia, the community-driven Pokémon encyclopedia.
Revision as of 05:25, 18 April 2012 by Rai Marshall (talk | contribs) (Oh hey, I finally got the stupid thing to work... I'll try to change its appearance later.)
User Tags
Personal | ||||||||
I am Rai Marshall, an editor of Bulbapedia. I have been with the wiki for a couple of years now, making the occasional edit here and there wherever I see fit. I do not work on many wiki projects, mainly because I am often busy with other things. Of the many Pokémon subjects, I am more knowledgeable in the main series games, but also have some understanding in the Trading Card Game, the original series of the anime and a select few manga works.
On the Bulbagarden Forums, I am known as 'Isamu Akai', named after the character from the Pokémon Pocket Monsters manga, which is my preferred Pokémon manga series.


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Michael Schwartz, better known by his stage name Mix Master Mike (born April 4, 1970), is an American turntablist best known for his work with the Beastie Boys.
Life and career
Born in San Francisco, California, Mix Master Mike is of German and Filipino descent. Known as a prolific and internationally influential DJ, Mix Master Mike came to prominence upon winning the 1992 New Music Seminar/Supermen Inc. DJ Battle for World Supremacy in New York City, becoming the first West Coast DJ ever to do so. In the same year, his turntablism collective Rock Steady DJs won the DMC World DJ Championships, establishing Mix Master Mike as one of the pre-eminent DJs in the industry. This success was followed by triumph in the 1993 DMC Championships, this time as part of a duo with DJ Qbert.
Mix Master Mike and DJ Qbert subsequently founded the turntablist group The Invisibl Skratch Piklz with DJ Apollo.
Mix Master Mike's most high-profile work has been with hip-hop group the Beastie Boys. Mix Master Mike worked with the band on Hello Nasty (1998), To The 5 Boroughs (2004), and Hot Sauce Committee Part Two (2011). He also appears on the Beastie Boys single "Alive", which was released in 1999 in support of The Sounds of Science retrospective anthology. From the studio to world tours, Mix Master Mike is now effectively the Beastie Boys' resident DJ, having replaced DJ Hurricane, who was preceded by Doctor Dré (not to be confused with Dr. Dre) who replaced Rick Rubin known as DJ Double R.
In 1994, after winning three consecutive DMC World Championships, it was rumored that Mix Master Mike and Q-Bert were asked to retire from further competition, so as to avoid monopolizing the title. This claim is disputed by the DMC World Championship Website. After retiring from the world of competitive turntablism, Mix Master Mike and Qbert became judges for the 1995 DMC Championships.
Mike has also helped fellow DJs produce their own albums, most notably, Wave Twisters, by DJ Q-bert.
Mix Master Mike is known for his heavy-hitting bass and intricate scratch routines. Mike's solo album Eye of the Cyklops won best electronic album in 2000 at the California music awards.
In 1995, he was honored with The Grand Wizzard Theodore lifetime achievement award from the International Turntablist Federation. He has collaborated with artists such as Ozzy Osbourne, Tommy Lee, Rob Zombie, Fela Kuti and Joss Stone, among others.
In 2002, Mix Master Mike contributed two tracks to Red Hot + Riot, a compilation CD created by the Red Hot Organization in tribute to the music and work of Nigerian musician, Fela Kuti, that raised money for various charities devoted to raising AIDS awareness and fighting the disease and featured many other contemporary hip-hop and R&B artists. He remade classic Fela Kuti songs, "Interlude: Gimme Shit" and "Water No Get Enemy."
Mix Master Mike is often credited with inventing the Tweak Scratch. The scratch is performed by moving the record back and forth while the platter motor is stopped. The inertia of the platter causes the sounds to slow and drop in pitch in an unusual manner. He is also well known for the unusual technique of using a wah-wah pedal, an effect most commonly used by guitarists, with his turntables.
Mix Master Mike is featured as a secret character that can be obtained through a cheat code in the 2002 snowboarding game SSX Tricky. He also contributed the song "Patrol Knob" to the soundtrack of the NTSC and PAL versions of the 2000 game Jet Grind Radio.
Mix Master Mike is one of 9 artists who participated in thetruth.com's Remix Project, in which he remixed the Sunny Side song "Tough Love".
On March 9, 2010 Mix Master Mike was a guest on the Cool Tricks segment of Yo Gabba Gabba. In December, Mix Master Mike provided scratches for a cover of Frank Zappa's "Willie the Pimp", which appeared on the iTunes compilation The Frank Zappa AAAFNRAAAA Birthday Bundle 2010, featuring rappers Darryl McDaniels and Talib Kweli and singing by Zappa's son, Ahmet Zappa. On Dec 2nd 2010, Skullcandy and Mix Master Mike launched the official Mix Master Mike headphones, released in all major marketplaces including Apple stores, worldwide.
In 2011, Mix Master Mike has joined Travis Barker for a few performances promoting Travis' debut album Give the Drummer Some - On February 10, 2011, performing "Can a Drummer Get Some?" on Jimmy Kimmel Live! with Travis Barker, Game and Swizz Beatz, and On March 7, 2011, performing "Saturday Night" on Conan with Travis Barker, Transplants and Elvis Cortez. It was then confirmed that Mix Master Mike will be performing with Barker again, joining Barker on his I Am Music Tour supporting Lil Wayne, through March–April 2011.
In June of 2011 it was announced that he was to present a Saturday night show on the alternative radio network Xfm from 6pm-7pm for an initial 13 week period commencing July 9. In May of 2012 Beastie boys along with mix master mike were inducted into the Rock n roll Hall of fame in Cleveland Ohio. In December of 2013 Mix Master Mike became the first turntablist to perform at The John F. Kennedy Center for the Performing Arts for The Kennedy Center Honors in honor of Herbie Hancock, performing "Rockit"
- Juko (1991)
- Anti-Theft Device (1998)
- Eye of the Cyklops (2000)
- Spin Psycle (2001)
- Return of the Cyklops (2002)
- Bangzilla (2004)
- NaPALM ROCKETS (DubStep) (2010)
- The Magma Chamber (2015)
EPs, singles, and Mixtapes
- Neck Thrust One
- Rescue 916
- Terrorwrist Delivery Service
- Memoirs of a Serial Wax Killer
- Mixmasterpiece: Muzik's Worst Nightmare (1996)
- Surprise Packidge (1999)
- 30 Minute Massacre (2001)
- Plazma Ryfle (2015)
- Live! Beatdown volume 1 (2006)
- Neckthrust One
- Rescue 916
- The Bolt-117 (2012)
Awards and credentials
- Featured in Hang the DJ by Marco & Mauro La Villa
- Cannes Film Festival, France


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D101 Browsers Galore: Next Gen for Mobile, Tablets, E-Readers & PCsWednesday, March 21, 2012 10:30 AM 11:15 AM Greg Notess,
Faculty & Graduate Services Librarian, Montana State University With the explosion of tablet and handheld browsers, the browser space is heating up. Internet Explorer (IE) beat out Mozilla to win the browser wars of yore, but now IE and Firefox are seeing increased competition from Google's Chrome, Apple's Safari, and a plethora of new browsers for smartphones, tablets, and e-readers. Meanwhile, IE and Firefox have launched new versions with significant changes. Come explore these web browser changes, unique features, search options, privacy issues, and more. Learn the impact for both users and web designers.
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"Lost" alum Emilie de Ravin is coming to "Once Upon a Time" Sunday (Feb. 12) as Belle, the fairy tale princess who sacrifices her freedom to save her friends and family in the ogre war. Just how does she do that? By becoming the captive of Rumpelstiltskin.
"[Belle] has always wanted to be the brave one and go out into the world and do something with her life and she has the chance to," says de Ravin. "She has a chance to save her family and her friends by going to live with Mr. Stiltskin."
Rumpelstiltskin is the "beast" role in the fairy tale of "Beauty and the Beast," which has us wondering if the relationship between Belle and Rumpel is the same as in the fairy tale – is there love there?
"There's a love," says De Ravin. "Not the same as where the fairy tale goes, but there's actually a really beautiful progression in their relationship … he finds himself smiling and laughing at things for the first time in a very long time."
"This friendship definitely turns into more than that," De Ravin continues. "But not in the same way as the animation. In maybe more of an adult reality sense, the way things don't always work out in the real world."
We can't wait to see it – Robert Carlyle has always been so great as Rumpelstiltskin that we can feel our hearts breaking already.
"Once Upon a Time" airs Sunday nights at 8 p.m. ET/PT on ABC. For all things "OUAT," check out ABC's official website.


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- Pro Sports Blogging - http://www.prosportsblogging.com -
FA reach tipping point?
Posted By thesportingmouth On Feb 10 2012 @ 1:29 pm In England,Soccer | No Comments
In years to come this might be the week that we look back upon as the tipping point. [1]
For reference "The Tipping Point" was a book written by a guy called Malcolm Gladwell at the start of this century in which he tries to pinpoint causes of change. Sound boring? Well mainly it is but one interesting insight in the book is that he describes the tipping point as "the moment of critical mass, the threshold, the boiling point" and I can't help wondering that this is what we've seen at Wembley in the last 8 days.
For starters we've seen speed and deciciveness of action and for those of us well versed in lobbing critical petrol bombs at the FA we know that these 2 attributes are about as common as a learner driver attempting their first 3 point turn. But rather than stalling in the middle of the road in heavy traffic, the FA performed the sports administration equivalent of a 60mph handbrake turn by immediately announcing that John Terry would be relieved of his captaincy duties once the courts had pushed his court appearance back to July, 1-0 to the FA.
They followed this up with a quick second by taking the decision without consulting Fabio Capello, a tactical masterstroke that I suspect they knew he would not only disagree with but would also feel compelled to comment on. So in taking a 2-0 lead they also set up their 3rd strike with a juicy piece of bait that no self-respecting, proud Italian would be able to resist and, sure enough, within 48 hours Fabio was whining to his Italian media friends that the FA were acting against his wishes. Voila. (or whatever that is in Italian).
At this stage the fat lady was warming up for the final kill as by Monday morning the admirable David Bernstein and colleagues knew that they had their man right where they wanted him, all they now needed was for the jury in the Harry Redknapp trial to do what the whole country was willing them to do by finding him not guilty and it's 4-0 to the FA, hat trick and man of the match performance for Bernstein and we can all go home happy. Sure enough the jury delivered (Harry against the tax man was there really ever going to be a different outcome?) and Bernstein could go into his Wednesday morning meeting with Capello with all the confidence of the Pakistani cricket team needing 10 English wickets for less than 100 runs – a sure thing if ever there was one.
So exactly one week after a court announcement that Terry would be tried after Euro 2012 we find ourselves in this fantasy land whereby an embarrassment of a captain has been sacked (again), a manager who we didn't want and who didn't want us has vacated his post and the man that we all want to replace him is not only available but free of the criminal charges that have been hanging over him for 5 years.
And so is it possible that we have reached our tipping point? Will England now play consistently well in major tournaments? Might we start winning penalty shoot outs? Will we no longer be blighted by injury, suspension, scandal and poor decisions? In other words will we be able to hold our heads high with all the smug self assuredness that German fans have been displaying since 1970 (i.e. my whole life)?
You know what- I just don't believe we're that lucky and tomorrow I'll wake up and I'll be back at Wembley on that wet night in Autumn 2007 looking on in disgust at the wally with the brolly and queuing up for 2 hours in the pissing rain to get a bus home.
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Canon EF 85mm f/1.2L II USM 35mm Primes
Product DescriptionRetaining the impressive optical performance and large aperture of the original EF 85mm f/1.2L USM, this new medium telephoto lens uses a Ring-type USM, high-speed CPU and optimized algorithms to achieve an autofocus speed approximately 1.8x faster than the original. The high-speed AF and circular aperture create a shallow depth-of-field that brings attention to the subject and blurs the background, which is ideal for portraits and weddings. The floating optical system, which includes an aspherical lens element, suppresses aberrations and ensures excellent imaging performance.
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a Professional Date Reviewed: July 4, 2007 Strengths: Amazing image quality f/1.2 aperture. f/1.2 aperture. (I know I said already but it's so good I'm saying it twice!) Beautiful isolation of subject from background. Beautiful smooth unbeatable bokeh. Solid weather sealed build. Superb lens flare control especially for a lens of this aperture. Superb sharpness even wide open is good. Silent Operation. Superb contrast, colour, chromatic abberation control and distortion control. Lens Hood and pouch included. Weaknesses: Slow focus compared to L lenses or 50mm f/1.4 & 85mm f/1.8. 72mm Filter not standard size for L lenses (Except 135 and 180 I suppose). Cost is huge compared to 85mm f/1.8 which is a d*** fine lens also. Bottom Line: Expand full review >>Duration Product Used: 6-10 years Price Paid: $1800.00 Purchased At: Calumet Similar Products Used: Canon 85mm f/1.8 USM Canon 85mm f/1.2 L MKI Canon 50mm f/1.4 USM Canon 50mm f/1.8 Zukio 50mm f/1.8 (Olympus) Sigma 50mm f/2.8 EX Macro Nikon 85mm f/1.8 Nikon 50mm f/1.4 Type of photography: People
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Chapter 05-2 - Sons and Lovers by D. H. Lawrence - Paul Launches into Life
Chapter 5 - Part 2: Paul Launches into Life. Classic Literature VideoBook with synchronized text, interactive transcript, and closed captions in multiple languages. Audio courtesy of Librivox. Read by Mark F. Smith.
Playlist for Sons and Lovers by D. H. Lawrence: www.youtube.com/playlist?list=PL99259BACFA366C8E
Sons and Lovers free audiobook at Librivox: librivox.org/sons-and-lovers-by-d-h-lawrence/
Sons and Lovers free eBook at Project Gutenberg: www.gutenberg.org/ebooks/217
Sons and Lovers at Wikipedia: en.wikipedia.org/wiki/Sons_and_Lovers
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The 74th annual Elam reunion will be held on Sunday, Aug. 5, at the Mulberry Grove Community Building.
A potluck lunch will be held at noon. Those attending are asked to take a covered dish to share and their own table service.
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View Poll Results: Mobile Suit Gundam 00 - Episode 10 Rating | |||
Perfect 10 | 54 | 33.33% | |
9 out of 10 : Excellent | 54 | 33.33% | |
8 out of 10 : Very Good | 26 | 16.05% | |
7 out of 10 : Good | 15 | 9.26% | |
6 out of 10 : Average | 6 | 3.70% | |
5 out of 10 : Below Average | 1 | 0.62% | |
4 out of 10 : Poor | 0 | 0% | |
3 out of 10 : Bad | 0 | 0% | |
2 out of 10 : Very Bad | 1 | 0.62% | |
1 out of 10 : Painful | 5 | 3.09% | |
Voters: 162. You may not vote on this poll |
Thread Tools |
2007-12-08, 07:46 | Link #45 |
Exitus Acta Probat
Graphic Designer
Join Date: Jul 2006
Location: Permanent retirement from raws-hunting
Age: 31
It doesn't remind of Lacus so much as it does Code Geass' Gekka (Toudou custom) or FMP!'s Codarl...but the AS' hair in that series actually served as a force-field emitter for the Lambda Driver...but in this case I surmise the Nadleeh's hair are simply wires connecting the Nadleeh to the sensors embedded in the outer shroud.
...Somehow this reminds me slightly of the Mars Jacket concept but more aesthetic and better executed IMHO.
Last edited by Renegade334; 2007-12-08 at 08:06. |
2007-12-08, 07:49 | Link #47 |
Senior Member
Join Date: Nov 2007
2007-12-08, 08:14 | Link #49 | |
Senior Member
Join Date: Dec 2005
Location: Le Mans, France
I don't remember the mention of force-field emitter on Lambda Driver equipped AS. |
2007-12-08, 08:52 | Link #51 | ||
Beautiful fighter.
Join Date: Dec 2005
Location: England, UK
Age: 30
The music used during Virtue transformation to Nadleeh was <3. Classic Kawai.
2007-12-08, 09:47 | Link #53 |
You are Dominated!
Join Date: Dec 2004
Location: Earth
Age: 28
Amazing episode! A 10 out of 10!
This is all fighting episode and the Virtue VS Tierens battle is really intense. Tieria shows he is a bastard again, instead of trying to save the captured Kyrios, he decides to vaporize him as well, saying his now trademark "You don't deserve to be a Gundam Meister". I have to laugh when Virtue gets its fat ass kicked. It shows how slow and useless it's actually. Until it 'casts off'. I have to admit, the hair and dual wielding the cannon do look cool. I wonder if Tieria will change his attitude from now on. He always thinks that the other Meisters are unfit since they violates orders and show off new weapons earlier than planned, now he shows off Nadleeh when he's in a pinch. Take that Tieria! You are not better yourself! Wow. Setsuna has no shooting skill, but he knows how to throw daggers and look cool! Hallelujah. I really like this sadistic bastard. . He's really cruel. He can kill Soma easily in this episode and no, he adjusts his rifle to non-fatal round and toys with her. And when he kills the HRL soldier, man, it scares me....I wonder why Allelujah is affected by Soma's brainwave so much but Hallelujah doesn't? I hate Wong Ryu Min. What gives you the right to criticize the Gundam Meisters? They are fighting for their life on the battlefield while you are drinking juice under the sunshine. Someone please kill her! Anyway, this series is getting better and better!
2007-12-08, 10:16 | Link #55 | |
Senior Member
Join Date: Dec 2005
PS For whatever it's worth, Lockon killed 7 MS and Setsuna 9 (according to their personal tally). |
2007-12-08, 10:17 | Link #56 |
Gundam Boobs and Boom FTW
Join Date: Dec 2005
Hallelujah is funny =). Just for the record, that wasn't Sergei that died but some random grunt.
What's Tieria moaning about? Maybe that he's not the perfection that Veda chose? Dunno why Sumeragi was crying...I wonder who's going to get with her if Lockon is going after Felt (though maybe he sees her as a little sister) and will go after Sumeragi (now that would be a good match!) It seems Lockon's the only normal meister, except he has an (evil?) twin. Though seriously I want to see more of Hallelujah. He's so sadistic and just pwns everything in sight no questions asked =). He's the Tieria Tieria wants to be =)
2007-12-08, 10:21 | Link #57 |
Senior Member
Join Date: Dec 2005
Yes, it gives an interesting, if vague insight into Tieria. I wonder if he's an android... or someone who has been heavily modified (far more than Soma). Certainly the way his eyes go suggests something digital. Maybe he's been constructed from multiple people...? Doesn't seem to be multiple personalities as such - more like 3 or more in 1.
2007-12-08, 10:42 | Link #60 | |
Join Date: Nov 2003
The cosplay girl mentioned at the end about how incomplete all the Meisters are even though the Gundams themselves are ideal. EDIT: I'm waiting for Tieria to do a cast off "himself". Probably there will be an animated sequence of all the bandages around his torso unravelling (and hitting some other Meister in the face if we extend the analogy with the Taozi >.>)
Last edited by Eleutheria; 2007-12-08 at 10:55. |
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"Gimme a C, gimme an R, gimme an A, gimme a B, gimme an S! What's that spell? Crabs! Yaaaay!
...And while I happen to be of the crab species, that cheer was actually a message from your last hookup designed to inform you of something that you now have.
Sooo, you may want to get that checked out."


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City of Franklin, TN
Home Sitemap ContactBoard of Mayor & Aldermen
The Franklin Board of Mayor and Aldermen (BOMA) is made up of nine people elected to make policy decisions for Franklin City government. Each of the eight Aldermen serve as an elected representative of the members of his/her ward. The BOMA enacts ordinances and serve on committees as appointed by the Mayor. Committees study various issues and make recommendations to the full Board. The BOMA meets twice a month for regularly scheduled meetings.
To be eligible for an alderman position candidates must be a resident of the state of Tennessee for more than one year and resident of the City of Franklin for at least six months immediately preceding their election to office. Aldermen must reside within the city during their term of office. Aldermen at large are not required to reside within any particular ward. The aldermen who are elected by ward must have resided in their respective wards for at least sixty days preceding their election and shall continue to reside within the ward during their term of office. Aldermen have staggered four year terms. Every two years elections are held in the City of Franklin. Voters elect the mayor and at-large aldermen during one election. Ward Aldermen are elected two years later.
Find out who represents you on the aldermanic Ward Map, then contact your BOMA representative to let them know your questions or concerns.
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Click links below to go to each Alderman's page or e-mail them directly using the addresses below each name.
Mayor Ken Moore(mailto:firstname.lastname@example.com) |
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Ward 3 Michael Skinner(email@example.com) |
At-Large Ann Petersen (firstname.lastname@example.com) |
At-Large Clyde Barnhill(email@example.com) |
At-Large Pearl Bransford (firstname.lastname@example.com) |


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/ UM&l GoUe <f& HE JAl]SEE ECHO folE XXIX ROCHESTER, MINNESOTA, MAY 4, 1962 NO. 13 |C Delegates Attend jple-to-People Meeting bring college people of Lnt nations together is the lose of People-to-People, ac- ,g to Governor Andersen, |e morning of April 13. Dele- . from JC, Dave Bluhm, Ed mck, Vicky Antonson, and Kopeland, heard the Gover- 1 promotion which previewed jsix-hour conference of stu- i from Mankato, St. Cloud, lehead, and Bemidji State Les, from St. Olaf, St. Schol- , St. Catherine, St. Thomas, Ihe St. Paul Seminary schools, I Brcinerd, Worthington, and ■ester JC's, and from Northern, Carleton, Macalaster, fordia, and the University of lesota. Students learned how jcould advance international ponding by setting up Peo- Ito-People programs like the which was originated fay the Ints af Kansas University in and conducted by all the |ight schools. sneed for American students |oke themselves known to the foreign students on our luses, and for the Americans ft to know the foreign stu- i, was greatly stressed by Rick js, Chairman of the PTP Job pient Committee at K. U., who along with Bill Dawson (also of K. U.) and Rayfer Johnson of U.C.L.A. explained PTP to the assembly. Often foreign students who want to acquaint themselves with the American people as well as to learn subject matter are subjected to sub-standard housing and prejudice, and form the opinion that American students are primarily interested in having a good time and beer blasts on week ends. These impressions of foreign students can be seriously detrimental; Nhkrumah, leader of Ghana, probably still harbors bitterness for the U.S.A. because of his unpleasant college residency in Pennsylvania. Friendship is what the foreign and American students need; friendship is what People- to-People provides by having its members greet international students upon their arrival on the campus, assist the students in finding employment, arrange industrial and farm tours, plus other trips and visits, correspond with students who have returned to their native countries, and hold discussions on international issuses. In the afternoon, after the college students had heard in the (Cont. on page 8, col. 2) S\ * < p°Peland, Dave Bluhm, Vicki Antonson, and Ed Villwock pose fally with the flag pole after attending a Student Council Ention jn Minneapolis. TWO LEADERS Verne Shea, present Student Council President, seems intent on ending Ed Villwock's career before it starts as 1962-63 Student Council President. Ed is Freshman Class Representative on Student Council this year. Villwock Elected President Ed Villwock, RJC freshman, was elected Student Council President for 1962-63 in recent college elections. Ed will use his past council experience as a background for carrying out his duties of working closely with the student advisor, conducting the council meetings, and working for the student body and for the betterment of the school. Ed served as a council representative in his senior year in high school and is the freshman representative at RJC. As an RJC council member, he has served on Social Committees, helped with planning the student activity budget, and has helped to plan the Spring Banquet. He also was one of four RJC students who attended a People to People convention in St. Paul recently. This convention was an attempt to study the problems of foreign students, and means by which the American students can assist fhe visitors with problems that may arise. Ed is Spring Formal The annual Spring Formal will be held May 12 in Coffman Hall at 9:00 P.M. The theme and decoration scheme will not be disclosed until the dance. also a member of the RJC dramatic group, the Rajesters. Ed will succeed Verne Shea, Student Council President for 1961-62. DeWaine Silker Named To Join RJC Staff As Math Instructor Joining the RJC staff in the Fall of 1962, as a full time mathematics instructor, will be Mr. DeWaine Silker. Mr. Silker, a native of Rochester, and a graduate DeWaine Silker 1000 Mark Reached Total enrollment for the 1961- 62 academic school year reached its highest peak yet at 1,004 including full time and special students. This is the first time in the history of the Junior College that the enrollment figure has topped 1,000. Scholarships Announced To Students Scholarships available for Junior College students were recently announced. Students are chosen on the basis of character, attitude, need, and academic achievements. All recipients will be announced at the Spring Banquet. The following scholarships are available to students who plan to take their sophomore work at JC. Three scholarships of $150 each are being offered by the First National, Northwestern National, and Olmsted County Banks to students enrolled in business or SLA. Students in engineering are eligible for the three scholarships of $100 each, awarded by O. A. Stocke Co., Utility Sales and Engineering Co., and Crenlo. Rochester Personnel Association is offering one scholarship of $125 to a student in business. A student enrolled in science is eligible for a $125 scholarship granted by Junior College in honor of Charles H. Singley. Theree scholarships are available to students graduating from JC in June. Rochester Education Association is granting a scholarship of $150 to a student who plans to continue in education and eventually to enter teaching. The student must be an active member of SNEA. A student of high grades and good character is eligible for a $250 scholarship (Cont. on page 8, col. 1) of the State University of Iowa, has two majors, one in mathematics and one in physical education. Two years ago he was given a leave of absence for a year from the National Science Grant, to do graduate study in mathematics, at San Diego State College, in California, where he received his Masters Degree in mathematics. He received his Masters Degree in Education at Colorado College, Colorado Springs, Colorado. Mr. Silker has a great deal of teaching experience. He is presently teaching af the Rochester Junior High School, and was for some time assistant wrestling coach.
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The author is a Forbes contributor. The opinions expressed are those of the writer.
Jerry Yang is a smart, capable, visionary executive. So why did stock jump 4% when he resigned?
We've seen it before. We'll see it again. And for the record, I'm not immune to Founderitis. I've had it too.
Founderitis can easily be caught. It creeps into one's system as a result of disconnection. When we disconnect from our people (our team at work), our purpose (why we're doing this after all--our mission) and our passion (the deep emotional commitment we feel to our mission).
When we disconnect we get arrogant. That's when the trouble starts.
Here are the four signs of Founderitis:
1) Shunning a golden parachute for your shareholders (and yourself). When Yahoo turned down 's acquisition offer a few years back many of us were amazed. Their strategy was failing, their business was plummeting, and Microsoft was going to take their pain away and put $44.6 billion in their pockets in the process. Why does this happen? Because the founder thinks their vision is better, they deserve a richer offer, the acquirer isn't worthy of them. When competitors are pummeling you and you have no solid recovery strategy, it's best to cop to the fact that the party's over. No point in serving cocktails and celebrating your independence as the ship sinks. Arrogance meter: 5 out of 5 (because many people are hurt in the process).
2) Severe Reality Distortion Field. We witnessed this recently with the price hike. Why hike the price? What's the justification? Where's the realistic connection with what the customer wants? "In hindsight, I slid into arrogance based upon past success," Reed Hastings said in his blog. "We have done very well for a long time by steadily improving our service…" and promising to "work hard to regain your trust. We know it will not be overnight.." Arrogance meter: 4 out of 5 (because you can recover from this).
3) Misguided mergers. Like really expensive designer clothes that are absolutely ugly, just because you can afford it, doesn't mean you should buy it. When big companies acquire small companies the Founderitis victim will do it out of: boredom, fascination/obsession/jealousy/fear with no business case, or the true desire to make 1 + 1 = 5. But mergers are tricky. After the glow of the press release, after the back-slapping and champagne swilling is over, the fact is most mergers fail to meet their potential. Yahoo buying Delicious or Flickr, 's acquisition of MySpace, Google's acquisition of Dodgeball, AOL's purchase of Bebo. The result? Promising companies with great potential and passionate users end up either shut down or marginalized. Arrogance meter: 5 of 5 (again because many people are hurt in the process).
4) No care for culture. We're seeing this now at Zynga. People matter. Easily 75% of the real work is done by your team behind the scenes. The flashy deals the executive forges need to be implemented by someone. And who might that be? Oops—the people that the founder doesn't talk to? The people without a career path, working inhumane hours and being told they're not delivering enough value? Hey! Way to motivate! Arrogance meter: 5 of 5 (yet again because many people are hurt in the process—but this time it's the people who care most about your company).
The cure for Founderitis is to reconnect. Look at Reed Hastings's blog. He's reconnecting in it--excellent. He's well on his way to recovery. Jerry Yang likely too--by stepping back he'll have an opportunity to realign with his passion for building great things and making a difference. Mark Pincus I am not sure about. I hope he'll cure himself by tapping into his initial passion, purpose and now people of Zynga.


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The shotgun is arguably the most common type of hunting firearm. The shotgun is a smooth-bore long gun capable of firing shotgun shells, projectiles which consist of either a large number of smaller pellets, known as "shot," or a single metal projectile known as a "slug." With the large number of wild boar and feral pigs now available for hunting in the Southern U.S., hunting with the shotgun has become one of the preferred means for taking this notoriously tough game.
Types of Shotguns
There are a wide variety of shotguns readily available to hunters. Primary types consist of the break-action shotgun -- single or double shot; the pump action, available in a variety of capacities ranging from three to eight rounds; and the semi-automatic. Both the pump, or slide action shotguns, and the semi-automatic shotguns give the user the advantage of high capacity and rapid follow-up shots, making them better for hog hunting than the break-action shotguns. A number of pump and semi-automatic shotguns are now available with sighted or scoped barrels specifically designed for taking medium to large game.
Recommended Shotgun Ammunition for Hog Hunting
While there are a wide variety of types of shotgun shells, only two of them are useful for shotgun hunting: buckshot and slugs. Buckshot is a devastating collection of several large pellets, often each the size of a 9 mm bullet, which spreads as it flies through the air. Most buckshot spreads at a rate of about one inch per yard, putting its maximum effective range at about 30 yards. Beyond this, slugs should be used. Slugs are a 1-oz. chunk of lead fired from a shotgun barrel. At close range, nothing is more likely to ruin a hog's day. Slugs increase the effective range of your shotgun out to 50 to 100 yards, depending on the type of slug, type of shotgun barrel and type of optics used.
Getting a Clean Kill
There are three factors that go into a clean kill: ammunition selection, caliber selection and marksmanship. Ammunition selection has already been discussed. For caliber selection, the shooter should pick a suitably large caliber of shotgun. Twelve- or 10-gauge shotguns are the only shotgun calibers considered powerful enough for hog hunting. Remember that the lower the shotgun gauge, the higher the caliber. Thus, a 12 gauge is a larger caliber than a 20 gauge. Using a caliber that is too small can prevent you from getting a clean kill and may cause unnecessary work on your part, as well as undue suffering to the animal. Finally, marksmanship consists of both knowing the effective range of your caliber and load, as well as being able to place the shots within the animal's vitals. The easiest place to shoot a hog is in the neck -- a neck shot will almost always ensure a critical hit. The head, heart and lungs are also viable targets.
Legal and Ethical Concerns
Shotguns have the added advantage of being legal for hunting in most states, even those that otherwise restrict hunting with rifles and handguns. This notwithstanding, you should always be careful to consult your state and local laws regarding the type of game, type of weapon and time of year before hunting. Additionally, you have an ethical responsibility as a hunter to make sure that you do not put the animal through any unnecessary suffering. You should always make sure that you have a good, clean shot and that you shoot the hog in the vitals to ensure a clean kill.
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- Hemera Technologies/PhotoObjects.net/Getty Images


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Lake Michigan North Shore View
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Lake Bluff, IL (Current Weather Conditions)
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Some plays are entertaining and others are meant to inspire. Hardin County Playhouse hopes to do both with a production of "12 Angry Jurors."
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I've read that the 2011 E92 sport suspension is able to handle pot holes alot better than previous E92 model year sport suspensions. Does anybody know what the change was if there were any at all?
I have heard the same but have no experience with previous models. I can tell you the 335is with 19s rides fairly well over all but the biggest potholes. I think the big change was in spring rates, maybe some shock valving too.
I test drove a 2011 335is with sport suspension and it seemed to me that it did better over rough surfaces than the previous models but not as good as my 2007 335i with regular tires and Koni FSD shocks. CA
I've had my 2011 335is for a couple of weeks and I drive in the city every day. The suspension feels super-solid and pretty damp, excpect when I hit something deep. Then it can be jarring, but I think it's relatively supple for such a performance-oriented suspension.
Damping sport suspension on 2006 330i I have a 2006 330i 6spd MT with sport package. The suspension is perfect on smooth roads (at limerock it was nirvana). But with the rough rodes of everday driving i want to make the suspension a bit more dampened. The car has the facctory 18" staggered wheels ..i got rid of the run flats ...its better but still want to consider more damping for the suspension. What are the possible solutions?
Haven't been here in a while. It is my car and it is Space Gray. The rims are style 196 OEM BMW rims (18s) CA


text: Formula One racer spends holiday slideways in a SevenJustin Hyde5/02/11 1:00pmFiled to: Hoon Of The DayHOTDLotusCaterhamMotorsportsHeikki KovalainenVideoClips41EditPromoteShare to KinjaToggle Conversation toolsGo to permalink To mark its purchase of Caterham, Team Lotus turned loose Formula One driver Heikki Kovalainen in the special Lotus-liveried edition Caterham Seven — a car so light it doesn't need a LCD readout to tell the driver "do a skid, bro." Advertisement For those scoring at home, or even if you're alone, Team Lotus is owned by magnate Tony Fernandes, and is fighting a court battle over the Lotus name and colors with Group Lotus, the luxury goods branding and image house with a sideline in cars overseen by Dany Bahar. At least someone's having fun.H/T to RX-EliseReply41 repliesLeave a reply


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You don't have to defy the laws of physics to stretch your money so it will last. Just plan wisely. Download PDF advertisementRelated Links:Retirement planning late in the gameUse annuities to protect your retirement?Dollar-cost averaging and retirementRelated Articles:Tax on IRA distributions?Part-time jobs for retireesManage retirement plans
You don't have to defy the laws of physics to stretch your money so it will last. Just plan wisely.
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After years of hating on the Affordable Care Act and vowing to repeal it, the Republicans are finally getting their wish. House Republicans released long-awaited legislation to replace it on Monday, and now the bills head to committees so they can have a field day marking them up. Keep in mind, this is all still ... Read more


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Adopting the Right Dog for You
How to find the right dog for you and your family
Welcome to Petfinder.com! The virtual home of 374,783 adoptable pets from 13,618 adoption groups
Friendliness towards dogs
Friendliness towards other pets
Friendliness towards strangers
Ease of training
Watchdog ability
Protection ability
Cold tolerance
Heat tolerance
The Border Collie is a bundle of mental and physical energy awaiting its chance to be unleashed on the world. Among the most intelligent and obedient of breeds. Given sufficient exercise, he is a dependable and loyal companion. He is intent on whatever he does and tends to stare, which can be unnerving to other animals. He also likes to chase other animals. He is reserved, even protective, toward strangers.
Few dogs are as work-oriented as the Border Collie. This is a dog that needs a job. He needs a lot of physical and mental activity every day to satisfy his quest for work. He enjoys being with his family. Its coat needs brushing or combing twice weekly.
Major concerns: CHD
Minor concerns: PRA, lens luxation, CEA, PDA, OCD, PPM
Occasionally seen: cerebellar abiotrophy, ceroid lipofuscinosis, deafness
Suggested tests: hip, eye
Life span: 10-14 years
Australian Shepherd
Bearded Collie
Belgian Malinois
Belgian Sheepdog
Belgian Tervuren
Australian Cattle Dog
Bouvier des Flandres
Canaan Dog
Some animal welfare organizations with Border Collies ready for adoption:
How to find the right dog for you and your family
Why adopting an older dog has many advantages
Prepare in advance to make sure your home is safe for your new pup


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They say never to mix business with pleasure, but it's hard not to in Massachusetts, where each of the four distinct seasons provides a unique backdrop for meetings and events. Have a meeting or conference to plan? Consider one of Massachusetts' many hotels, function facilities, and attractions that cater specifically to small meetings (fewer than 500 attendees), team-building, and incentive planning. When it's time to get down to business, this is the place to find the perfect meeting venues from Boston to Worcester and everywhere in between. And don't forget the "all work and no play" rule; come early or stay late to enjoy all that Massachusetts has to offer.
Foodie Finds: It's all Here
Looking for fun things to do and see in Massachusetts?
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Waterfront accommodations; Two guest rooms with a shared bath, queen size beds w/down comforters/quilts. Harbor views, stone patio,... more
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hsv.rb Meeting: December 16
The next meeting of hsv.rb (the Huntsville Ruby Users Group) will be held this Thursday, December 16, at 11:30 a.m. The location is the HudsonAlpha Institute, and it sounds like we'll be meeting in a room "on the first floor facing the atrium on the bistro side." So there you go. If you'd like to buy lunch there and just bring it to the meeting, you can stop by the Atrium Cafe.
Bryan Powell will be leading a discussion of MacRuby, which is an implementation of Ruby on the Objective-C runtime. Here is a nice introductory article that demonstrates how to build a simple Cocoa application in Ruby, using MacRuby.
Another topic of discussion is the hsv.rb community project. There's been some discussion of it here, but the goal is to nail down some plans so that we can start this in earnest in the new year.


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1984 Arctic Cat Snowmobile Parts
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Anne Hathaway didn't just show off a dramatic gown and killer dominatrix-style boots at the New York City premiere of 'Les Miserables.' Unfortunately, Anne showed a little more than she planned as she stepped out of the car. Photographers quickly discovered- and snapped pictorial evidence- of the fact that she wasn't wearing any panties. Oops! Anne said:
"I was getting out of the car and my dress was so tight that I didn't realize it until I saw all the photographers' flashes. It was devastating. They saw everything. I might as well have lifted up my skirt for them."
When this happens to some celebrities, I have a strong suspicion it's planned. I honestly don't think that was the case for Anne, so I'm cringing for her. Hopefully her SAG nomination will cheer her up!
Photos by GG/FAMEFLYNET


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"Dress for the job you want, not for the job you have"
"Leaving a little to the imagination is sexy"
These are just a few of the pieces of advice handed down from first-time life coaches and stale fortune cookies. These words of wisdom continue to be handed out like prostitution leaflets on a Vegas street because they are tried and true, for the ages, informative instructions that continue to inspire and reward.
As someone who has been certified in EUTS (Everything Under The Sun) from the Professional Institute of Placeimadeup, I feel compelled to bestow some of my (not yet) patented words of higher knowledge to my readers, especially the intellectually inferior among you (no Le Names, but you know who you are.)
Knowing how to carry oneself is important because it can mean the difference between getting the job or getting a friendly email that says 'You were one of the worst applicants we've ever had. Ever' but disguised in a thinly veiled 'Did not meet the requirements'. I know what you meant, Janice Beekman of Mansonite Bros. Corp. LLC.
Dressing appropriately and stylishly can also mean the difference between a flirtatious look of interest from that attractive person across the room and that attractive group pointing at you and laughing from across the room.
To alleviate any gender confusion, I have separated the tips into two categories: Men and Women. For those of you who fit into neither or both categories, take away whatever resonates with you. Also, which bathroom do you use? I mean, like, in public. Whoa, whoa, I'm not judging! I'm just curious.
1. If you wear a padded bra and the right guy comes along, the jig is up.
2. Your glasses probably don't make you look as much like Tina Fey as you think they do.
3. You will reach an age when the schoolgirl-look receives less 'Oooh's and more 'Ewww's.
4. If you rely solely on your hipbones to keep your pants up, you are too skinny.
5. A pair of Converse will always look cute.
6. A short, denim skirt always has a trailer park connotation.
7. No one should admire your sideburns.
BONUS TIP: Your cat, Miss Mary J. Prancy Paws, should not have better clothes than you.
1. The 'Zack Galifianakis look' is not a good look even on Zack Galifianakis.
2. Wearing sunglasses backwards on your head will always make you look like a dick, even if you aren't.
3. Using tweezers to avoid a unibrow is not a slippery slope to becoming gay.
4. Just because white briefs are on sale 12 for $4, doesn't mean you should buy them.
5. Aftershave is always appreciated, whether you've shaved or not.
6. Unless you are Jim Morrison, no leather pants. (HINT: You are not Jim Morrison)
7. Supercuts usually aren't.
BONUS TIP: Dressing up should involve a tie, not your less-wrinkled pair of Dockers.
If I've missed anything that you feel would be beneficial to the general population, please let me know. If it's good advice, I will claim that I intended to use that in the next list and steal it from you. My lawyer will immediately dig up dirt from your past and you will be ruined, I repeat RUINED, if you contest.


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Bendito pediatrics is dedicated to helping families raise happy and healthy babies and kids. From birth through adolescence we're here to provide the highest quality medical care while avoiding unnecessary intervention..
Babies are born with protection against certain diseases because antibodies from their mothers were passed to them through the placenta. After birth, breastfed babies get the continued benefits of additional antibodies in breast milk. But in both cases, the protection is temporary.
Read MorePediatric well-baby check-ups are an important part of your baby's first year of life. These periodic, routine appointments will help keep your baby healthy and ensure he or she is developing properly. At each appointment, the pediatrician will perform a complete physical exam, which includes measuring your baby's height, weight, and head circumference; and he or she will ask you about your baby's general health and development. Schedule yours today
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9 Best Secret Hotels in the World
Each year, Budget Travel scouts out undiscovered hotels in popular destinations, from Italy to California wine country. Here, we pull the best of our picks from around the world, all for less than $210 a night.
Rockhouse Hotel, Jamaica
Seclusion isn't easy to come by in the party town of Negril, with its sprawling resorts and thumping dance beats, but that's exactly what Rockhouse delivers, primarily to hip couples and families hoping to avoid anything close to a spring break experience. Rockhouse's rounded, thatch-roof villas are strung atop a low cliff carved with stairs that lead down to the warm waters of Pristine Cove. The 20 villas peeking out of the jungle right at the cliff's edge start at $220 a night, but the long buildings set a bit farther back are easier to pull off—five studios with sea views ($150) and nine standard rooms with garden views ($125), all with minibars, safes, A/C, and mosquito netting around four-poster beds. Guests chill out at the 60-foot horizon pool, take yoga classes, or stroll along the property's serpentine paths and stepping stones, which inevitably lead to quiet nooks, isolated beach chairs, and what most people say are the best sunset views in Jamaica. The action on Seven Mile Beach—including the nightlife hub of Jimmy Buffett's Margaritaville, live reggae on the sand at Alfred's (Tuesday, Friday, and Sunday), and Roots Bamboo (varies)—is a quick $5 to $10 cab ride away. Closer to your cabana—right next door, actually—is Pushcarts at Pirates Cave, where patrons eat curried goat before jumping off the cliff and swimming into the sea cave underneath. 876/957-4373, rockhousehotel.com, from $125.
Albergo California, Positano, Italy
Maria Cinque makes a point of chatting with every one of her guests, if not at check-in (which her son Gianni sometimes handles), then at breakfast the next morning. She's particularly delighted to meet Americans, as she and her husband Antonio lived in the Bronx for nine years, returning to Italy in 1974 to run a family hotel five minutes' walk from the center of Positano—and to teach their children "what it means to be Italian," in Maria's words. Six of the 15 guestrooms are in the original Palazzo Bruno, dating from 1777, including four upstairs rooms with 18th-century ceiling frescoes. Many regulars prefer the ground-floor rooms 51 to 55 because they open directly onto the magnificent, long entrance terrace and enjoy postcard views of Positano framed by ivy trailing off the shady trellis. Rooms without sea views (they actually look out to a wall) cost $65 less—an option certainly worth considering, since all guests have access to the terrace. Each of the California's rooms is spacious, and seems even more so due to minimal furnishings. At sunset, small groups gather on the terrace to sip wine, plan the next day, and pinch themselves, realizing that they've got the same view as the chichi Le Sirenuse hotel down the street for one-third the price. 011-39/089-875-382, hotelcaliforniapositano.it, from $200, breakfast included, closed mid-November to mid-March.
- Related: World's Weirdest Hotels
Fundana Villas, Corfu, Ionian Islands, Greece
If there's any doubt whether Spyros Spathas values his heritage, just look at the reception area of his Fundana Villas, where a more than 200-year-old stone olive press serves as a reminder of the Spathas family's six generations of local history. It's been 29 years since Spathas converted his farm's stables and outbuildings into 12 guest bungalows, but the accommodations have been updated with flat-screen TVs and modern kitchenettes. And the views from the rooms are as glorious as ever: No. 10 has two wrought-iron balconies that look out on the Ropa Valley, and No. 12 takes in the green slopes of Mount Pantokrator to the northeast. A guide for the Greek National Tourism Organization for more than 35 years, Spathas maintains a half-mile hiking path to the 18th-century Monastery of St. Onoufrios, open every other Sunday, and leads weekly botanical walks through the area. His 26-year-old son, Foivos, just opened a traditional Corfiote restaurant on the grounds, serving dishes such as veal with garlic sauce and pan-fried artichokes from Fundana's gardens. If you feel inspired to venture off-property for dinner, stop in at Elisavet's Taverna in the nearby village of Doukades. There, the grandmotherly proprietress sits in front of her establishment encouraging visitors to try the kokoros pastitsada—rooster over macaroni—a local specialty she's been making for 20 years. 011-30/26630-22532, fundanavillas.com, from $67, breakfast $9.
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SIMULATING THE HELICASE MOTOR OF SV40 LARGE TUMOR ANTIGEN by Yemin Shi A Dissertation Presented to the FACULTY OF THE USC GRADUATE SCHOOL UNIVERSITY OF SOUTHERN CALIFORNIA In Partial Fulfillment of the Requirements for the Degree DOCTOR OF PHILOSOPHY (COMPUTATIONAL BIOLOGY AND BIOINFORMATICS) May 2012 Copyright 2012 Yemin Shi
Object Description
Title | Simulating the helicase motor of SV40 large tumor antigen |
Author | Shi, Yemin |
Author email | email@example.com;firstname.lastname@example.com |
Degree | Doctor of Philosophy |
Document type | Dissertation |
Degree program | Computational Biology and Bioinformatics |
School | College of Letters, Arts And Sciences |
Date defended/completed | 2012-05-01 |
Date submitted | 2012-05-01 |
Date approved | 2012-05-01 |
Restricted until | 2012-05-01 |
Date published | 2012-05-01 |
Advisor (committee chair) | Chen, Xiaojiang S. |
Advisor (committee member) |
Warshel, Arieh Rohs, Remo |
Abstract | Helicases are motor protein that utilize the energy derived from NTP binding and hydrolysis to translocate and unwind DNA/RNA during the replication. Understanding the energy coupling of NTP hydrolysis cycle to the DNA movement is the key to understand the DNA replication mechanism in the molecular motor. The helicase domain of simian virus 40 large tumor antigen (SV40 LTag) is a ring-shaped AAA+ domain that participates in viral DNA replication and host cell growth control. Recent SV40 LTag structure studies have provided a set of high resolution structures in different nucleotide binding states. Hence, in this thesis we use LTag helicase as a model protein, and present the first systematic simulation study on the mechanism of the LTag helicase motor. Our work includes three major sections: first, we model the LTag ATPase activity and the helicase activity based on the biochemistry experiment results. This model indicates that the LTag helicase subunits work in highly cooperative patterns. When the origin DNA is presented, the helicase translocates DNA in a sequential pattern. When the fork DNA is added, the helicase works in a semi-sequential pattern, otherwise, the subunit cooperativity is not significant. Second, we present the first simulation study on the ATP binding/hydrolsis procedure using the non-equilibrated molecular dynamics method, the results suggest a three-stage Locker-binding model. We evaluate the energy profile using the LRA version of the semi-microscopic Protein Dipoles-Langvin Dipoles method (PDLD/S). The energy profile matches the experimental results. Thirdly, we investigate the electrostatic energy that guides the single-strand DNA (ssDNA) translocation process and propose a unidirectional translocation model. To accomplish this work, an ssDNA/LTag complex model is built using the structure information from the LTag helicase and the E1 protein-DNA complex, a two-dimensional effective electrostatic free-energy landscape is calculated based on the ssDNA/LTag model, and the unidirectional model is proposed by evaluating the energy landscape. The time dependence of the coupled protein-DNA motion is explored by simulating the translocation process using a renormalized method. Altogether, our theoretical and simulation study advanced our understanding of the fundamental molecular mechanism underlying the directional movement of ring-shaped helicase motor. |
Keyword | computational simulation; binomial model; molecular dynamics; hHelicase motor; simian virus 40; large tumor antigen; ATP binding; DNA unwinding; DNA translocation |
Language | English |
Part of collection | University of Southern California dissertations and theses |
Publisher (of the original version) | University of Southern California |
Place of publication (of the original version) | Los Angeles, California |
Publisher (of the digital version) | University of Southern California. Libraries |
Provenance | Electronically uploaded by the author |
Type | texts |
Legacy record ID | usctheses-m |
Contributing entity | University of Southern California |
Rights | Shi, Yemin |
Physical access | The author retains rights to his/her dissertation, thesis or other graduate work according to U.S. copyright law. Electronic access is being provided by the USC Libraries in agreement with the author, as the original true and official version of the work, but does not grant the reader permission to use the work if the desired use is covered by copyright. It is the author, as rights holder, who must provide use permission if such use is covered by copyright. The original signature page accompanying the original submission of the work to the USC Libraries is retained by the USC Libraries and a copy of it may be obtained by authorized requesters contacting the repository e-mail address given. |
Repository name | University of Southern California Digital Library |
Repository address | USC Digital Library, University of Southern California, University Park Campus MC 7002, 106 University Village, Los Angeles, California 90089-7002, USA |
Repository email | firstname.lastname@example.com |
Archival file | uscthesesreloadpub_Volume4/etd-ShiYemin-698.pdf |
Title | Page 1 |
Contributing entity | University of Southern California |
Repository email | firstname.lastname@example.com |
Full text | SIMULATING THE HELICASE MOTOR OF SV40 LARGE TUMOR ANTIGEN by Yemin Shi A Dissertation Presented to the FACULTY OF THE USC GRADUATE SCHOOL UNIVERSITY OF SOUTHERN CALIFORNIA In Partial Fulfillment of the Requirements for the Degree DOCTOR OF PHILOSOPHY (COMPUTATIONAL BIOLOGY AND BIOINFORMATICS) May 2012 Copyright 2012 Yemin Shi |


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Our mission is to reduce the suffering and death of animals in our town by implementing the Trap/Neuter/Return (TNR) Program for feral cats. We provide them with feeding programs, promote spay/neuter of all companion animals, educate the public on local animal issues, and offer advice/assistance to residents dealing with homeless cat situations or adopting out a pet cat that might otherwise go into a kill shelter situation.
We are a 501(c)(3) organization, meaning your donation is tax-deductible!


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WGBH Openvault
Where In Time Is Carmen Sandiego?; Erie Canal Digger
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- Series
- Where In Time Is Carmen Sandiego?
- Program
- Erie Canal Digger
- Program Number
- Series Description
Arch villainess Carmen Sandiego remains at large, wreaking havoc in history. In each episode Carmen and/or one of her gang go back in time to steal a key historical object, the theft of which could change the course of history. Three contestants--using logic, judgment and their knowledge of history--pursue Carmen and her crooks in a time machine called the Chronoskimmer, recover the loot and restore it to its proper place in history. Lynne Thigpen returns as the Chief; Kevin Shinick is featured as the "Squadron Leader"; music is contributed by (house band) "The Human Engine." Series release date: 1996
- Asset Type
Broadcast program
- Media Type
- Genres
- Children's
- Game Show
- Topics
- History
- Creators
- Taylor, Kate (Series Producer)
- Citation
- Chicago: "Where In Time Is Carmen Sandiego?; Erie Canal Digger," WGBH Media Library & Archives, accessed March 30, 2017, http://openvault.wgbh.org/catalog/V_BFB08CFBD292495B80C08F9980DC9C81.
- MLA: "Where In Time Is Carmen Sandiego?; Erie Canal Digger." WGBH Media Library & Archives. Web. March 30, 2017. <http://openvault.wgbh.org/catalog/V_BFB08CFBD292495B80C08F9980DC9C81>.
- APA: Where In Time Is Carmen Sandiego?; Erie Canal Digger. Boston, MA: WGBH Media Library & Archives. Retrieved from http://openvault.wgbh.org/catalog/V_BFB08CFBD292495B80C08F9980DC9C81


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Bedard, Pirates defeat Rockies, 6-2
July 18, 2012 4:15 PMDENVER -- Just when it seemed Erik Bedard's season was falling apart, a 10-day break and some behind-the-scenes adjustments helped him put it back together.
For one night, at least.
Bedard pitched his best outing in more than a month as the Pirates beat the Rockies, 6-2, Tuesday night at Coors Field, a notorious hitter's ballpark.
"Starting the second half in Colorado is not what I wanted," Bedard said, "but the results came out good. We'll build on that."
He allowed two runs, one earned, on eight hits over 6 2/3 innings as to earn his fifth win of the season and snap a streak of five consecutive losses in games that the left-hander has started.
It was his sixth quality start of the season in 18 outings and his first win since May 8, when the Pirates beat the Kansas City Royals, 4-2, at PNC Park.
"Erik has a lot of personal pride," manager Clint Hurdle said. "Always has. And the one thing about him, what you see on the outside doesn't necessarily equate to what's going on inside. He's a fierce competitor out there. He's a man that's connected to his craft and wants to do well."
After a strong start to the year, Bedard, the Pirates' opening day starter, posted a 7.39 ERA in June and July entering Tuesday. He hasn't pitched past the fifth inning in half of his starts this season and hadn't completed five innings in four of his past seven starts entering Tuesday.
That prompted Pirates Hurdle to push Bedard to the end of a reshuffled pitching rotation, allowing him time to work on a few fixes that Hurdle and pitching coach Ray Searage identified. A veteran, Bedard was eager to try and figure out what was wrong with his performance.
"Just an experienced guy trying to tighten some things up," Hurdle said. "Not overreacting, but just reacting."
Hurdle said the key to Bedard's outing Tuesday was his ability to have a consistent release point, which allowed him to get all of his pitches in play. During his time down, Bedard threw two bullpen sessions with Searage and got a little extra rest.
"The rest always helps, made me feel a little stronger," Bedard said.
On Tuesday, he struck out four pitches and was buoyed by a big-breaking curveball that he threw for strikes. He walked four batters but threw 60 of his 94 pitches for strikes.
He left the game after loading the bases in the seventh, which put the tying run on first base. But Jared Hughes got Michael Cuddyer to fly out to centerfield on a full count to end the thread.
Andrew McCutchen hit his 22nd home run of the season -- and his longest home run of the season -- putting him one shy of last season's total, a career high.
McCutchen turned on a 1-1 slider in the fourth and belted a high-flying ball that soared above the mile-high mark at Coors Field, six rows from the top of the stadium, before gravity pulled it down.
The ball barely stayed in fair territory, but it cleared a utility tunnel and bounced around the concourse in left field, 442 feet away from home plate as the Pirates (50-40) tied the score, 1-1.
It was one of the hardest hit balls McCutchen can remember.
"That was a pretty good shot," he said. "A homer's a homer, though."
They ran away with the game in the fifth inning, piling four runs to turn a one-run deficit into a three-run lead and chase Rockies starter Christian Friedrich from the game.
Friedrich issued a pair of walks to start the inning, and after retiring the next two batters, he surrendered three consecutive singles as the Pirates surged ahead, 5-2. The inning featured nine Pirates batters and four hits -- all singles.
Friedrich, a rookie, lasted 4 2/3 innings and allowed five earned runs on seven hits with three walks and two strikeouts. He took the loss, his seventh of the season.
The Rockies (35-55) grabbed a brief lead in the bottom of the fourth. Bedard walked Wilin Rosario to start the inning, and Josh Rutledge followed with a triple that landed down the right-field line and rolled around in the corner before Drew Sutton corralled it.
Alex Presley's second error of the season allowed the Rockies to claim a 1-0 lead in the third inning. With two outs and Marco Scutaro on third, Cuddyer hit a tailing fly ball toward the gap in left-centerfield. Presley chased it down, but when he tried to backhand the ball, it glanced off the outside of his glove and fell to the grass.
The error allowed Scutaro to score from third and Cuddyer to reach second.
piratesMichael Sanserino: firstname.lastname@example.com, 412-263-1722 or on Twitter @msanserino. First Published July 18, 2012 4:15 AM


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An arrest warrant was issued yesterday for a Toledo man, charging him with the Jan. 18 shooting death of a Chicago man at a house on Mentor Drive, police said.
Patrick Munn, 28, of 1018 Eve sham Ave., was charged with aggravated murder in the fatal shooting of Israel Benitez, who was found in his van in a parking lot at Cherry Street and Central Avenue.
Mr. Munn is the second man accused in the case. James Munn, 40, who police allege was the triggerman, remains in the Lucas County jail awaiting a trial set for Nov. 7. He was arrested a few days after the shooting and indicted on aggravated murder and aggravated robbery charges.


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Problems? Is your data what you think it is? | |
PerlMonks |
Re^5: Not Again ... *sighs*by Paulster2 (Priest) |
on Sep 27, 2004 at 18:00 UTC ( #394270=note: print w/replies, xml ) | Need Help?? |
Gee, castaway, I was actually wondering if you ever slept ;-) Paulster2 You're so sly, but so am I. - Quote from the movie Manhunter. In the immortal words of Krystal Morton, when asked "Who loves ya?, answered "My Mommy".
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Down to the Wire
by Dallas Stars Staff / Dallas StarsThe Dallas Stars are one of the hottest teams in the league right now, winning 13 of the last 16 games. Unfortunately for them, two teams are just as, if not more, hot than the Stars and they happen to both be in the Pacific Division.
The Anaheim Ducks are 10-1 in their last 11 games while the San Jose Sharks have won six in a row. Both squads won big games at home against some of the top teams in the East on Monday evening, chipping away at Dallas' lead in the division.
But while the Stars do watch the standings on a daily basis, they are more concerned with their own play and winning the only games they can control – their own.
"We know that if we take care of our own business, everything else will take care of itself," said Brenden Morrow. We're playing some desperate teams right now and we like to raise our intensity and our desperation levels too. These teams we are playing like Phoenix, Vancouver and Nashville are fighting for a playoff spot. But we are fighting for home ice and winning the division. There are things we need to focus on too like taking care of our game and winning the games we can control."
The Stars control their own destiny, as they will play the final eight games of the season against all of the teams in the Pacific. All of the games will be big and should make for an interesting stretch run.
"If you look at the overall points, three of the top five or six teams in the league are in one division," said Head Coach Dave Tippett. "We have games against them, we are battling for position with them, and we better make sure our game is in order. You look at both of those teams (Anaheim and San Jose) and they look like they are building right now. We need to continue to build our group."
Dallas has played 69 games on the season - the most in the Western Conference. Anaheim and San Jose can pull closer by winning their games in-hand, but it probably will still come down to the head-to-head match-ups.
"The standings have been tight from start to finish, and the teams that can string it together the longest will come on top," said Mike Modano. "We are going to get caught up in games played here soon. It's important that we take care of those games until we are all evened out in that situation. It may come down to the very last games. We have our work cut out for us. We've held up our own lately but we have to continue to win."
The Stars have been red-hot since the All-Star Break but Tippett is quick to point out that they haven't clinched anything yet. The focus is on continuing to play well and hit the post-season on a high note.
"I would rather be going in making sure you play well on the way in," he said. "I think you carry your momentum into the playoffs. Let's not get ahead of ourselves; we haven't made anything yet. Let's put things in perspective here. This is all well and good, and everybody's talking about playoffs. We are still along ways away from playoffs."
Dallas hosts Phoenix on Wednesday (7:30 pm, FSN, WBAP). Get tickets here.
Petersen Added
The Stars recalled center Toby Petersen from the Iowa Stars on Tuesday. Petersen has 21 goals and 51 points this season, leading Iowa in scoring in 63 games. He has 155 games of NHL experience and adds some depth to the Stars' roster.
"When Jokinen and Halpern were traded, those were two guys who could play center for us," Tippett said. "We are looking to adding another depth player that can play center for us. We want to get Petersen integrated with our team. He has been arguably their best player in Iowa so now he'll come and spend the rest of the year with us and make sure he's ready."
Injury Update
Tippett said Tuesday that defenseman Matt Niskanen might return on Wednesday vs. Phoenix.
"He looked pretty good today, so we'll see," Tippett said. "There is an old saying, 'You can play hurt but you can't play injured.' When you get injured you've got to take the time to heal and then move forward. It's not going to be the last injury he has because he's going to have a long career. We have to make sure he's ready."
Mike Ribeiro (elbow) and Brad Richards (ill) both did not skate with the team on Tuesday but are expected to play on Wednesday.
"Ribeiro skated earlier and he'll be fine. It looks like he will be good," Tippett said. "I think both he and Richards will be players (Wednesday)."
Sergei Zubov continues to rehab his foot and still is shooting for a return to skating in a couple of weeks.


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Among all the stars, editors, and socialites sitting front row at spring fashion week, it was a pint-size girl in glasses and a quirky hat who stole the show. "I'd hear people going, 'Who is she? A blogger?' " says flashbulb-magnet Tavi Gevinson. "I was thinking, I don't get it either!" Rodarte's Kate and Laura Mulleavy, early fans of her cutting fashion commentary, understand the appeal. "After we read Tavi's blog [Style Rookie], we e-mailed her immediately," the Mulleavys say, following it up by sending her a pair of hand-knit tights from their fall 2008 show. How else is a thirteen-year-old from the Chicago suburbs to get her hands on the designer must-have of the moment, tailor-made for her tiny frame? Now there's a whole collection of clothes for her to choose from that fits both her size and unique taste. "Tavi defines Rodarte for Target," the sisters say. "She's curious and discerning." But Tavi insists, despite her privileged relationship with the designers, she's a fan like anybody else. "They have their vision, which is so magical." The collaboration's filmy slip dresses and lacy takes on those famous tights share runway's "dark undercurrent," according to the designers, but "there are affordable pieces any girl should have in her wardrobe." After all, not every teen has a fashion fairy godmother (or two). "I'm lucky Kate and Laura were among the first people I met in the industry," says Tavi, who's since scored more bold-name admirers, plus the cover of avant-garde magazine Pop. "It's great to be shown the ropes by such smart girls." Sounds like she's a natural. "Tavi's a dreamer, and that definitely reminds us of ourselves when we were younger," the Mulleavys say. --EVONNE GAMBRELL
Click "read more" to see two pieces from the Rodarte for Target line


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Posted on November 14, 2016
As great as DAWs are, it's a drag to control the transport and create fades and automation with a mouse. Most musicians prefer a real fader and transport controls that they can touch.
That's why the FaderPort was created, which connects to your computer via USB and delivers complete transport controls for fast and efficient recording, along with a high-quality, touch-sensitive, motorized fader for writing fades and automation.
Feel is crucial when you're spending countless hours recording and mixing. So the ultra-affordable FaderPort features the same high-quality, touch-sensitive, long-throw, motorized Alps fader that is found in expensive control surfaces and digital mixing consoles. With its 1,024-step resolution and dual-servo drive-belt motor, the response will be smooth and seamless.
Compatible with virtually all major DAW programs, the FaderPort enables you to record perfect fades and write single-channel or grouped-channel volume, mute, and pan automation in real-time.
Control your DAW's Solo, Record-enable, window selection, Play, Stop, and Record functions. Manage markers and punch in and out with a footswitch (not included). The FaderPort makes it fast and easy.
You can even create your own custom key mappings. And if you use PreSonus' Studio One DAW software, your FaderPort will be automatically recognized and can be used to tweak virtually any plug-in parameter.
So put down that mouse and get back in touch with your music. Get the PreSonus FaderPort.
Computer System Requirements
Buttons and Knobs
No reviews available.
Posted on November 14, 2016
Posted on April 24, 2013
Posted on December 07, 2010


text: The Beats Pro by Dr. Dre high performance professional stereo headphones from Monster provide reference-quality audio in a stylish design! These Dr. Dre Signature studio headphones are ideal for sound engineers, DJs, musicians, and hard core music lovers. The Monster Beats Pro lightweight and durable aluminum frame stands up to long-term professional use and also won't resonate and introduce artifacts that interfere with your sound. Keep your sweet Monster Dr. Dre Signature Beats Pro studio headphones clean with the included anti-microbial cleaning cloth and a storage case! Monster Dr. Dre Signature Beats Pro Studio Headphones Feature:


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In it, but not of it. TPM DC
U.S. Hits Debt Ceiling
They are refusing to raise the debt limit without substantial cuts to government spending and entitlement programs. GOP leaders on Capitol Hill continue to vacillate between claiming that the consequences of default would be smaller than the consequences of not cutting spending -- "failing to do something about the debt would be far worse in the long-run than failing to raise the debt limit," said Senate Minority Leader Mitch McConnell (R-KY) on the Senate floor Thursday -- and admitting that they're using the threat of a default to make good on long-standing conservative commitments -- "What better time to do something about the debt than in connection with raising the debt ceiling?" McConnell said at a press conference the same day.
The brinksmanship comes despite the fact that some of the GOP's strongest allies in the business community and on Wall Street are pushing for a swift resolution to the fight.
Still, Republicans have thus far set the terms of the debate, at least in the public realm. They insist they will not accept increasing revenues as part of any deal. They want to implement budget process reforms that will make it easier to cut spending in the future, and say they'll only raise the debt limit by as much or less than the "trillions" in spending cuts they're able to enact as part of a deal. Underneath that, they've expressed willingness to negotiate the precise cuts to discretionary, defense, and entitlement spending. But their opening bid -- the House GOP budget -- includes enormous cuts to Medicare and Medicaid. Indeed, the GOP's top budget guy, Rep. Paul Ryan (R-WI), is expected to double down on his proposal to slash and privatize Medicare in a speech today. House Speaker John Boehner (R-OH) said Sunday he sees no substantial movement from the Obama administration in his direction -- increasing the sense that a deal is still far off.
However, the precise details of negotiations between House and Senate leaders and the White House, led by Vice President Joe Biden, remain tightly held. So there's likely a gap between the perceptions presented in public statements and the reality behind the scenes. And that gap will likely grow as we approach August, and the consequences of dithering and the pressure to avoid calamity mount.


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Viva's top stories
• Global Glamour: Interior designer Sandra Nunnerley in New York.
• Win an outdoor hanging chair worth $685, from online marketplace The Market.
• Isabella Blow: A tribute to a supreme fashion fantasist.
It's no small feat to be named in the Architectural Digest 100 list of the world's top designers and architects, but that's just one highlight in the fascinating life of Wellington-born interior designer Sandra Nunnerley.
Her passion for life has seen Sandra live in Sydney, Paris, London and now New York, and travel in Peru, New Guinea and Tibet. Her interiors have a subtle sensuality and easy glamour, as you will discover in our fascinating interview. You're bound to be inspired.
- Amanda Linnell, Viva editor


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'Over Here!' New York City During World War II
Central Library, Foyer Gallery Cases
We Couldn't Have Done It Without Brooklyn
by Lorraine B. Diehl
This exhibition is a physical extension of my book. It is meant to summon a deep sense of nostalgia for the way we were during the war years.
I grew up in Hell's Kitchen when it was a pretty tough neighborhood. As a child I found great drama and romance in the area. All of my work evolves from my love of New York City. The city is always at the center of my books.
"Meet the Author" - Lorraine Diehl
Central Library - Dweck Center
Sunday, April 25, 2010 1:30 p.m.
Film Series: War and the City - Curated & Hosted by Lorraine B. Diehl
Central Library - Dweck Center
Tuesday evenings at 6:30 p.m.
April 13, 20, 27, May 4, 11 & 18, 2010
Lorraine B. Diehl has also written The Late, Great Pennsylvania Station, The Automat: The History, Recipes, and Allure of Horn & Hardart's Masterpiece and Subways: The Tracks That Built New York City. Her work was featured in an exhibition based on on The Automat at the Museum of the City of New York. She is currently working on a book about growing up in the city of the 1940s and 50s.
To contact the author:
email@example.com | www.powwmedia.com/lbdiehl/
This exhibition was supported in part by a generous grant from the BIL Charitable Trust.
Brooklyn Navy Yard
Brooklyn Public Library -
Brooklyn Collection
Victory Garden: Mrs. Louis Sternberg of 17th Avenue, Brooklyn
Brooklyn Public Library -
Brooklyn Collection
Grain Terminal
Gowanus section of Brooklyn
Culver Pictures