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After installing Mountain Lion, the key which usuaaly has ~ character has a different one [paragraph].
I can't get it to work.
I can't change keyboard type [neither in system preferences nor using KeyboardAssistant [it says that there are no unknown keyboards]] and when I open up Ukelele it reports correct character under the key :/
What else can I do to get the correct character?
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Ask Mac Questions and Get Answers from Experts ASAP
Hi there Terry,
The 07 ipod is a 30GB ; and the model no. is A1136; EMC No. is 2065.
In regards to the other question; the computer I am planning to connect to does'nt have the itunes library that has previously synced with my 2007 ipod. I used my dads' computer in Texas(which I think he may have gotten rid of, and I'm in Florida). Everytime I hook it up to my computer it gives the message of: Itunes has detected that this ipod is not the default audio player...would you like to make it the default player?' Something aroung those lines, but if you choose accept (so you can sync your ipod) I think it erases the library on the 07 ipod, and that is just scary. yikes! I hope this info helps! Thank you so much for your help.
Best Regards,

subset: commoncrawl


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#515 Macy's
- Market Cap As of May 2016
- $12.8 Billion
- Ticker
- Industry
- Department Stores
- Founded
- 1830
- Country
- United States
- Chief Executive Officer
- Terry Lundgren
- Website
- http://www.macysinc.com
- Employees
- 157,900
- Sales
- Headquarters
- Cincinnati, Ohio
Macy's on Forbes Lists
- #515 Global 2000
- #312 in Sales
- #589 in Profit
- #1,095 in Assets
- #872 in Market value
Macy's, Inc. operates department stores. The company provides services through Internet under two brand names: Macy's and Bloomingdale's that sells wide range of merchandise, including men's, women's and children's apparel and accessories, cosmetics, home furnishings and other consumer goods. It also operates seven Bloomingdale's outlet stores. It provides services through its subsidiaries which include Macy's Systems and Technology, Inc. and Macy's Merchandising Group, Inc. The company's Macy's Systems and Technology, Inc. subsidiary provides operational electronic data processing and management information services to all of the Company's operations. It's Macy's Merchandising Group, Inc. subsidiary designs and markets Macy's private label brands and certain licensed brands. The principal private label brands currently offered by Macy's include Alfani, American Rag, Bar III, Belgique, Charter Club, Club Room, Epic Threads, first impressions, Giani Bernini, greendog, Greg Norman for Tasso Elba, Holiday Lane, Hotel Collection, Hudson Park, Ideology, I-N-C, jenni by jennifer moore, John Ashford, JM Collection, Karen Scott, Martha Stewart Collection, Material Girl, Morgan Taylor, so jenni by jennifer moore, Sky, Studio Silver, Style & Co., Style & Co. Sport, Tasso Elba, the cellar, Tools of the Trade, Tools of the Trade Basics, and Via Europa. The company's logistics division provides warehousing and merchandise distribution services for its operations. Macy's was founded by Rowland Hussey Macy Sr. on March 6, 1929 and is headquartered in Cincinnati, OH. More »
More on Macy's
More on Global 2000
The World's Largest Companies 2016
Steve Schaefer, Forbes Staff -
China's Largest Companies 2016
Shreya Agarwal, Forbes Staff


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Earlier this year, we reported that Bloc Party was ready to end their hiatus in September, aka the month we're in right now. But it appears that while the time off might expire, the band's frontman might not be involved with whatever the band is up to. At least, that's what we're gathering from a recent article in NME. In the piece, lead singer Kele Okereke says that he hopes he hasn't been fired and that he doesn't "really know what's going on."
Apparently the rest of Bloc Party has been spending time in the studio, though it's been happening without Okereke. At least, that's what he's saying.
"I was actually having lunch about three weeks ago, just here on 8th Avenue, and I saw somebody walk past and I recognized the haircut," he said. "It was Russell. I was like, 'Hey!,' but he didn't see me and I followed him around the corner and then I saw Matt, Gordon and Russell all standing outside this rehearsal space. They all went inside."
Word, guys? You're just going to get back together and not have your frontman on board? Weird.
FaltyDL, Slugabed, Starkey - Ninja Tune Announces New EPs From Starkey, FaltyDL & Slugabed | R.E.M. R.E.M. Break Up |


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Within This Page
While their parents work, seven out of ten American children under the age of six participate in some form of care outside the home. Because many of them spend up to 12,500 hours in a child development center-most of their waking hours-the facility must be designed to provide safe, nurturing, and stimulating environments essential for the healthy development of our children.
Hallway with reading niche at child development center in Des Moines, Iowa. Architects: Wells, Kastner, Schipper
WBDG accepts the majority view that all child development centers should stress quality care, and child growth and development. To this end, all child development centers are encouraged to provide well-illuminated, active and passive activity areas that accommodate a range of play and organized learning as well as serve the needs of adult staff and parents, and facilitate staff-child relationship building.
There are nationally recognized accreditation agencies, such as the Nation's Network of Child Care Resource & Referral (NACCRRA) and the National Association for the Education of Young Children (NAEYC), that identify requirements for quality child development programs and facility conditions, including safety, sanitation, natural daylight, and classroom size.
Building Attributes
While child development centers can take many forms-they can be stand-alone or part of some larger structure; they can be urban or rural; they can be large or small.
A. Types of Spaces
Child Development Centers will contain a variety of space types depending on the hours they are used, the age of the children attending, the number of children attending, and the setting for the center. Fundamental space types may include, but are not limited to, the following:
- Child-friendly classrooms
- Meeting or community space for children and adults
- Child-friendly and adult restrooms
- Outdoor and indoor play areas
- Office space for staff
- Meeting space for adults
- Clinic
- Food service space
- Storage space
- See also WBDG Child Care Space Type
All child development centers should seek to:
B. Be Homelike
Like a home, a quality child development center is a place where children can:
- Relax and be themselves
- Have ample natural light in all spaces were children will spend time, especially the classrooms
- Have a sense of arrival and welcome upon entering the center for both children and parents
- Use indirect lighting as main ambient lighting to avoid a "commercial" flavor
- Feel and be safe and secure
- Find different places for different kinds of learning
- Work and play using different furnishings and varied lighting
- Avoid institutional, unnatural finishes and textures. Use natural finishes to the extent possible, emphasizing a "hand-made" appearance
- Have no sharp edges: ½" bull-nose on all exterior corners at child-level gypsum and trim typical. Integral bull nose corner beads are recommended.
- Provide Comfortable Environments
C. Be Child-Sized
Preferably, facilities designed for children should have:
- Child-sized furniture appropriate to the specific age group served
- Ceiling heights should be varied, low enough for intimacy, and high enough to avoid a monotonous spatial experience
- Windows at children's level
- Doors, sinks, toilets, and water fountains that are "child friendly" and mounted at appropriate heights
- Functional / Operational
D. Encourage Autonomy
Child development centers should be designed to allow children to:
- Independently address bodily needs such as hunger, thirst, using the toilet, and sleep
- Set their own pace
- Choose activities and toys
- Choose their own friends and companions - or be alone
- Be active or still
- Create three-dimensional projects that are protected from destruction by everyday traffic through classroom space
- Promote Health and Well-Being
E. Invite Self-Expression
Such facilities are characterized by:
- Restraint in color and furnishings (e.g., neutral tones for backgrounds and ceilings, with warm colors for accents)
- Space for children's art, located at the children's eye level together with a well-thought out and safe way of hanging art and displaying three-dimensional projects
- Space for objects that children bring to share or that have special meaning
- Changing displays more than permanent graphics
F. Provide Space, Indoor and Outdoor Physical Activities
Child development centers should have playground and multi-purpose play space for inclement weather. These areas should allow:
- Running
- Playing ball
- Climbing, swinging, sliding, and balancing
- Storage of play items such as tricycles
- Access to nearby toilets
- Controlled access for maintenance
Playground areas at a child development center in Honolulu, Hawaii allow children to interact with their peers and explore their surroundings. Landscape & Playground Designers: Moore Iacofano Goltsman (MIG)
G. Have Outdoor and Indoor Spaces for Nature
When possible, they should contain places to:
- Dig in dirt or sand
- Play with water
- Grow seeds, flowers, and vegetables
- Investigate animal life
- Collect rocks, leaves, or other specimens
- Contain a variety and scale of natural elements such as trees, flowers, and shrubs
- Have quiet time, away from the "crowd" while still being able to be supervised
- Places for large motor activities such as climbing and riding wheeled toys
- Storage shed(s) for storage of outdoor equipment
- Have a (typically) 6'-0" fence completely surrounding the play area
H. Be Structured, Yet Flexible
This means that different spaces in a facility:
- Can be recognized by children
- Are for quiet and active play
- Can be rearranged by children for their own activities
- Contain adequate storage facilities to avoid a chaotic impression
- Beyond Accessibility to Universal Design
Staff can monitor and control access to the child development center from desks positioned at the entry such as the one shown in the photo. World Bank, Washington, DC.
I. Include Appropriate Space for Parents and Teachers
This includes places to:
- Think and plan
- Meet and communicate
- Host visitors
- Store equipment
- Keep record
- Come together and celebrate as a community
J. Be Safe, Secure, and Healthy
This includes provisions and strategies to ensure that:
- Children are not abused by adults in the center
- People/personnel do not have uncontrolled access
- There are adequate washing facilities
- Finishes are easily cleaned
- Attention is paid to good indoor air quality as well as to the use of daylighting, non-toxic building materials and improved maintenance practices
- Equipment, furnishings, and finishes do not contain asbestos or lead
- Ensure Occupant Safety and Health
Relevant Codes and Standards
As the number of child development centers increases, more and more agencies, states, and municipalities are requiring that child development centers within their jurisdictions meet minimum facility and operating standards. However, in most states the facilities requirements are limited to relatively few and minimal health and safety issues such as the adequacy of bathrooms, egress, and lighting. The most comprehensive facilities standards available at present, sometimes cited in state and municipal codes, are those promulgated by federal agencies. Among the organizations that have led the way toward the definition of comprehensive child development centers criteria are the U.S. General Services Administration, Department of Health and Human Services, and the Department of Defense.
- National Clearinghouse for Educational Facilities (NCEF)-Managed by the National Institute of Building Sciences, NCEF is the largest source of school facilities information in the world. NCEF provides information on planning, designing, funding, building, improving and maintaining safe, healthy, high performing pre-kindergarten through grade 12 schools and higher education facilities.
Executive Order
Executive Order 13693 Planning for Federal Sustainability in the Next Decade, mandates buying products that reduce environmental impact. The Environmental Protection Agency's (EPA) Comprehensive Procurement Guidelines (CPG) lists designated products that federal agencies are required to purchase. Two specific product categories apply to the development of play yards: Park and Recreation Equipment and Playground Surfacing.
Federal Government
- U.S. Access Board-Provides information on site accessibility as well as building access to and within the center.
- U.S. Department of Health and Human Services
- U.S. General Services Administration
- Department of Veteran Affairs
- VA VHA 420 Childcare Development Center
Department of Defense
- UFC 3-210-04 Children's Outdoor Play Area
- UFC 4-740-14 Design: Child Development Centers
- UFGS 11 68 13 Playground Equipment
- UFGS 32 18 16.13 Playground Protective Surfacing
- Department of the Army
Private Sector
- ASTM F-355 Standard Test Method for Impact Attenuation of Playing Surface Systems, Other Protective Sport Systems, and Materials Used for Athletics, Recreation and Play, 2016
- Consumer Product Safety Commission
- National Association for the Education of Young Children (NAEYC)
Major Resources
Building / Space Types
Youth Centers, Educational Facilities, Child Care
Design Objectives
Functional / Operational, Productive, Secure / Safe, Sustainable
Project Management
Federal Agencies and Organizations
- GSA Child Office of Child Care-The primary mission of GSA's Child Care Operations Center of Expertise is to ensure that federal families receive high quality care for their young children in child care centers located in GSA managed space.
- National Association for the Education of Young Children-An advocacy organization for preschool care and education
- National Child Care Association-A trade association for private, for-profit child-care facility operators
- National Child Care Information Center-A publicly funded resource that links information and people to ensure that all children and families have access to high-quality comprehensive child care services
- National Children's Facilities Network-A coalition of nonprofit financial and technical assistance intermediaries involved in planning, developing, and financing facilities for low-income child care and Head Start programs
- National Clearinghouse for Educational Facilities (NCEF)
- Nation's Network of Child Care Resource & Referral (NACCRRA)
- BIPS 07 / FEMA 428 Primer to Design Safe School Projects in Case of Terrorist Attacks and School Shootings
- Caring for Our Children: National Health and Safety Performance Standards-Guidelines for Early Care and Education Programs, 3rd edition, by American Academy of Pediatrics, American Public Health Association, National Resource Center for Health and Safety in Child Care and Early Education, 2011. Elk Grove Village, IL: American Academy of Pediatrics; Washington, DC: American Public Health Association.
- Child Care Design Guide by Anita Rui Olds. New York, NY: McGraw-Hill, 2000.
- Creating Environments for Learning: Birth to Age Eight by Julie Bullard. Pearson Education, 2010.
- Greening Early Childhood Centers by Mike Lindstrom and Amy Gillman. LISC, 2010.
- Head Start Design Guide by U.S. Department of Health and Human Resources. 2005
- Infant/Toddler Rating Scales by Thelma Harms and Richard M. Clifford. FPG Child Development Institute of the University of North Carolina at Chapel Hill. Revised Edition, 2003.
- Play and Playscapes by Joe Frost. Albany, New York: Delmar Publications, Inc., 1992.
Points of Contact
- Ania Shapiro: U.S. General Services Administration (GSA) Child Care Operations Center of Expertise. 1800 F Street, NW, Washington, DC 20405.


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During the winter months the Adirondacks become one of the most popular locations in the country for winter outdoor activities as the entire area becomes a frozen playground.
Spend a winter weekend with Summit Base and our guides will instruct your group in basic winter outdoor skills such as camping, cooking and safety.
Contact Summit Base, infosummitbase.com, for more information.
Ice Climbing Our Ice Climbing program is featured here.
Winter Camping If you are going to snowshoe to an ice climb in the mountains you might as well get the full experience and stay overnight in the wilderness. Winter survival skills are taught as well as winter food preparation and cooking, cold weather backpacking skills and winter mountaineering safety. See most awesome winter landscapes and become a part of an Adirondack tradition.
Trek coordinators will discuss proper winter clothing with you before your arrival to ensure a fun and safe experience.


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MoD spends £22 million a year on Christian chaplains
A Freedom of Information request to the Ministry of Defence (MoD) by the NSS has revealed the Armed Forces spend £22 million annually on Christian chaplains and currently employ 280 chaplains across all three services.
The FOI revealed that a quarter of all army chaplains are either on medically limited deployability (18%), or are medically non-deployable (7%). Just 20 out of the 150 army chaplains are currently on active service. As a rule, only 30% of chaplains are preparing for, on, or recovering from military operations at any one time.
All chaplains employed by the MoD are commissioned officers. The starting salary for a military chaplain is £37,172 on appointment, rising to £55,857 after 15 years' service, but senior chaplains receive more.
The NSS has written to defence minister Andrew Robathan to question the spending, asking that either churches assume funding of their chaplains themselves, or that the MoD converts the role of chaplains into a secular "pastoral care" service, for which anybody can apply.
A MoD spokesman has said the spending of £22m a year on military chaplaincy is "currently being assessed".
The MoD employs and funds chaplains, but their authority comes from their Sending church. At present, the permitted Sending churches are Anglican, Roman Catholic, Methodist, Baptist/URC/Congregational, Church of Scotland/Presbyterian, Elim and Assemblies of God.
The armed forces also retain five civilian chaplains to care for Buddhist, Hindu, Sikh, Jewish and Muslim recruits. There have been calls for the establishment of Humanist chaplains, who would offer support to those with no spiritual beliefs.
Stephen Evans, spokesperson for the National Secular Society said: "A significant part of a chaplain's role is to provide pastoral support – but to all service personnel, not just the religious. It is therefore important to question the Christian monopoly in this area.
"If the MoD determine there is a place for pastoral support in the military in addition to counselling and psychotherapy services already offered, then those positions should be open to any professionals with the skills to provide necessary support, regardless of their religion or belief.
"If religious groups want specific representation, then they should fund their own chaplains, and not expect salaries to be paid from the military budget, which is already under immense strain."
In a recent letter to the National Secular Society, a serving soldier expressed concern about what he described as "wasteful" MoD spending on chaplains, and also about the homophobic attitudes of some of the churches approved to send their ministers into the forces.
A statement on homosexuality on the US Assemblies of God website states: "Clearly on every front whether it be moral, spiritual, physical, or psychological, the practice of homosexuality has proven itself devoid of any individual good or social benefit."
A call by the NSS to the UK branch of the church confirmed that this is a position they also hold.
Another Sending church, the Elim, made headlines when one of its followers, Iris Robinson, former MP and wife of Peter Robinson MLA, First Minister of Northern Ireland, compared the sexual abuse of children to homosexual relationships. Ms Robinson stated in Parliament: "There can be no viler act, apart from homosexuality and sodomy, than sexually abusing innocent children." When contacted by the Belfast Telegraph, Mrs Robinson reiterated her views and said she was following Scripture.
Stephen Evans commented: "The attitudes of some of the Sending churches hardly seem consistent with a service that describes itself as committed to equality and diversity. The appropriateness of any "moral leadership" such chaplains can offer the armed forces is highly questionable."
Defence cuts announced last year will see Harrier jump jets, the Navy's flagship HMS Ark Royal and planned Nimrod spy planes axed and 42,000 MoD and armed forces jobs cut by 2015. The RAF and Navy will lose 5,000 jobs each, the Army 7,000 and the Ministry of Defence 25,000 civilian staff.
Earlier this year, a defence select committee led by MP James Arbuthnot claimed cuts to the military budget could leave the British armed forces with no choice but to abandon operations beyond 2015.
See also:
Military chaplain funding queried by secular group (BBC)
Evangelical, Catholic chaplains say they'll perform no same-sex weddings


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View Poll Results: How much can you bench in relation to your body weight?
- Voters
- 349. You may not vote on this poll
15 4.30% -
half to all body weight
118 33.81% -
body weight to bodyweight X 1.5
160 45.85% -
body weight X 1.5 to 2 x Bodyweight
48 13.75% -
2 x Bodyweight to 2.5 x Body weight
5 1.43% -
>2.5 X body weight
3 0.86%
Thread: whaddya bench?
1/09/2005 1:42pm, #111
- Join Date
- Mar 2004
- Location
- Posts
- 706
- Style
- Wing Chun
--Originally Posted by antonanton
1/09/2005 2:17pm, #112--
Yeah, that is bad. One shouldn't be trying to set any benchpress records like Bahua and Asia, but you should be able to bp your own weight.
1/09/2005 2:17pm, #113--Originally Posted by Asia
Accident? Is this some obscure comic book reference, or did a lorry run over you or something?Mr Politically Correct GIJoe6186:
Fat people disgust me in every way imaginable. I was at Freindly's with my girl tonight and saw a bunch of fat fuckers. I felt sorry for the pavement they were killing and the people who had to see them. .
1/09/2005 2:35pm, #114--
Where have you been? I was in a car accident last summer and shattered my elbow.. Docs put it back together but wouldn't instal bionic parts like I wanted. :new_termi
Xiao Ao Jiang Hu Zhi Dong Fang Bu Bai (Laughing Proud Warrior Invincible Asia) Dark Emperor of Baji!!!
Didn't anyone ever tell him a fat man could never be a ninja
You can't practice Judo just to win a Judo Match! You practice so that no matter what happens, you can win using Judo!The key to fighting two men at once is to be much tougher than both of them.
1/09/2005 2:39pm, #115--
I want bionic parts. Ghost me.
1/09/2005 2:47pm, #116--
179 cm height body weight 90 kg
Bench press 155kg for single rep
( dunno pounds, I use SI units ...)
Bench press only once a week if that.
prefer the olympic lifts.
1/09/2005 3:04pm, #117--
Well you're roughly 180lbs and can bp around 310ish. I'd say that's good :-)
1/09/2005 10:25pm, #118
- Join Date
- Dec 2004
- Location
- New England
- Posts
- 335
- Style
--341lbs for 5'10, 198lbs is pretty solid man!
People I know who are my weight but about 3-4 inches shorter can lift/bench so much more... bastards! I guess my arms help me with range, heh! In fairness, I don't try to add much more muscle mass than I have. However, that doesn't take away from you, that's quite good. Do you juice at all?
1/09/2005 10:29pm, #119--
Am I the only one that uses thick bars?
1/09/2005 10:48pm, #120--
Some people are just bp machines. I have long arms and long legs. My BP is alright. BP is no way to determine true power though as I believe. See what a person squats and DL's. Or shoulder presses, and Squat Press/Leg Presses..


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Stop Costa opening in Ripon
Ripon needs more retail to increase visitors; Costa coffee will take a valuable retail space without attracting footfall to the city. Ripon has an excellent array of independent cafes and coffee shops that buy supplies locally. They support local cottage industry keeping money in the local economy. Costa will not... it will dilute the trade of independent cafes and buy pre prepared food form large wholesalers outside the local economy.
Please support your city and independent traders by signing our petition to keep Costa out.


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Hey Arrow,
Have you been wearing these? I'm thinking of getting a pair and I'm curious about the fit. What size do you wear in Barrie/Trubalance and Leydon? How do the NST's compare? I'm sure everybody would love to see some pics as well.
Hi Mike,
Yeah, I've been wearing them in rotation with other Alden boots.
I wear a 9D in Trubalance (with full insole) and stuck with the same size with the Aberdeen NST
and Chukka NST (Barrie last). Since the toe area is a bit slimmer with the Barrie/Aberdeen, I only
use a half-insole. I will take pics soon.


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Looks like I have the honors of kicking off a new feedback thread for a great Head-Fi'er!
I just sold my pair of LA2000 Lites to shane55. He's a great guy to talk to, and the transaction was a very pleasant experience from start to finish!
Overall, he's a great buyer; no need to hesitate before doing business with him. I would definitely do business again with him in the future.
Thanks for a great transaction!


text:
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Major improvements are awaiting patrons of Cranberry's popular swimming complex and municipal center.
The municipal center, located on Rochester Road, is undergoing a major renovation that will expand the heavily used parks and recreation area and the preschool, replace the roof and the HVAC system, and give a facelift to the carpeting and the lighting in the building.
"This building is about 25 years old. We want to make sure we stay on top of things and continue to keep customer service friendly," said Assistant Township Manager Duane McKee. He said the $3.3 million project will be finished this year.
The biggest aspect of the work is a redo of the 7,000-square-foot area that formerly housed the township's police department. About half the space will be for expanded preschool rooms and the balance will be for activity and meeting rooms. "We could do some small aerobics classes or be able to schedule more meetings (for community groups,)" Mr. McKee said.
A large portion of the roof of the building is to be replaced as is the heating and air conditioning system. Portions of carpeting in the most heavily traveled areas of the building will be replaced and high-efficiency lighting fixtures will be installed. Also, the rear parking lot at the building will be resealed.
Work will be bid in February and the project is expected to finished by November.
Meantime, township staff has decided to recommend construction of a new baby pool at the North Boundary Park swimming complex. Officials had been debating whether to expand the zero-depth-entry area of the pool or construct a separate facility. Mr. McKee said township supervisor have yet to give their stamp of approval to the plans but staff has decided to recommend a separate baby pool. He said the idea is to construct it between the existing pool and water spray playground. The project cost will be about $1.2 million. He said the facility "will definitely have some 'wow' factors. We want something that will b very interactive for the kids," he said.
He expects the project to get under way after the pool closes for the 2014 season. It will be finished and open for use before the 2015 season.
Karen Kane: email@example.com or 724-772-9180
Karen Kane: firstname.lastname@example.com or at 724-772-9180.


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Well said mushky - that's exactly what i was about to post. :)Originally Posted by mushky
That looks bloody awesome for an Xbox game. I'm of the opinion that FPS games are meant for the PC mainly down to the control system. But nobody can say those screenshots make the graphics VERY impressive for a current-gen console.
HDTVs can go up to 1920x1080 resolution.Originally Posted by Stompy
TV res is 720x576 isn't it?
Originally Posted by Isotopian
Dude, a normal TV's resolution is 320 by 240- thats half of how small the crappiest monitors can go. It's pretty durn small, which is the only reason HL 2 can even run on a console.
But, in the meantime, we have something far more exciting for you. It's from Valve, and not only is it from Valve, it's actually from Valve - we have a man at their offices in Seattle as we speak. We've got some info coming, and it's going to be good - hence our new header image on the front page. Tune in tomorrow!


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The No One Killed Jessica actor was recently photographed at the airport with her rumoured beau, Aditya Chopra
There have been years of speculation about the equation between Rani Mukerji and Aditya Chopra and one of the biggest reasons for that being Adi is fiercely protective about his personal space. In fact, till he was photographed for the first time in 15 years recently, the joke doing the rounds was that he was a myth and Aditya Chopra didn't really exist. However, Rani came clean about her relationship in a recent interview. "I have nothing to hide. I went for my holiday and returned from it in public. I was just tired as I had a long flight but there was absolutely nothing to hide," she said. Wethinks it is quite a bold statement to make, especially when the rest of her contemporaries are not talking about their personal lives.


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Donald T. Levine, MD
a user ...
a user ...
Ratings based on 6 reviews
Reviews (6)
5 out of 5 stars Rhinoplasty
All Thanks to Dr. Donald T Levine - Nyack, NY
The cost of nose job done by Dr. Donald was very reasonable. After talking to Dr. Donald I realized how big mistake I had made by going to a Rhinoplasty surgeon and not getting all the details before I went under knife. My nose job was a disaster. However, meeting Dr Donald was a calming experience. He explained me what had gone wrong, used imaging to explain me what he could do and kept my expectations within realm of possibility. After revision rhinoplasty which was a minor surgery, I am back to my normal routine. Everything looks fine. I wish Dr Donald had done my first surgery!
5 out of 5 stars Facial Reconstructive Surgery
Now my Face and Nose Are Good Like They Were Before Accident - Nyack, NY
5 out of 5 stars Age Spots Treatment
Dr. Donald is a Very Professional and Caring Doctor - Nyack, NY
Dr. Donald is a very professional and caring Doctor. I did a lot of research before deciding to have my anti aging surgery by Dr.Donald T Levine. During my consultation with him and his staff, I felt so comfortable that I had no doubt this was the right place for me to have my surgery done. After surgery I am happy and satisfied with the results of my surgery. Dr. Donald is a very professional and caring Doctor and I would recommend him to all my friends. He made me very comfortable and he changed my life. Thank you Dr Donald!
5 out of 5 stars Nose Surgery
Magic Fingers - Nyack, NY
Dr Levine has magic fingers! I had snoring problem and he cured it without any major surgery. He did a small surgery from inside and in one week, I had fully recovered.
5 out of 5 stars Nose Surgery
My Girlfriend Made my Decision Making Easier - Nyack, NY
Getting a nose job done was a tough decision for me. I waited almost five years before I got it done! I had consulted several doctors before I decided to go with Dr. Levine. The reason was simple – when my girlfriend revealed that she had her nose done and Dr. Levine was her doctor, the decision making looked so much simpler! I don't know whether it was due to my girlfriend's presence or otherwise, I always felt comfortable at Dr. Levine's place. She knew the process and had already briefed me like some of other doctors I had met. But this doctor was really impressive. He created and showed me before and after imaging, how it would look like after surgery. Post surgery recovery was painful initially. First few days, I thought whether I did right thing or not by going for surgery. There was swelling and pain. But after few days it was better. After one year, I love my nose and there are almost no scars. I still have the same girlfriend and she always reminds me that my beautiful nose is due to her.
5 out of 5 stars Nose Surgery
Dr. Levine is Good and Experienced - Nyack, NY
When I contacted Dr. Levine for my snoring problem, one thing I noticed that he was very experienced and must have treated a lot of patients with snoring problems. He explained me the issue with my nose and suggested surgery. I knew it before I contacted him so it was not surprising. But I was anxious about it because it would be my first surgery. But he took time to explain me the surgery process and post recovery related issues. That did certainly helped me. I visited twice more to his clinic before I was operated. His staff helped me with my insurance claims. I am very happy with the results and my husband is happier. P.S. I forgot to tell you – my nose looks nicer now and that was complimentary gift from Dr. Levine.
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Doctoral Degrees
Printer-friendly versionSend by emailI want to congratulate Ralf Heron, Marc Sanders and James Klein for their Doctor in BA Quality Management. It was a long way. Lets use this opportunity to open a chat for this Subject.Ralf is publishing a new Book very soon and is holding a lecture at FG University on June 8 th.
Marc is joining the Tahlmer Group and can bring us a lot of input to whats new in QM.


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Pentax has released three new compacts. From the top, we have the Optio WS80 waterproof compact. More of a lifestyle camera, it is not quite as resilient as its sister model, the W80 (though is still certified to depths of up to 1.5 meters for two hours). The 10MP camera features an SP (Super Protect) coating on its 35-175mm zoom lens. It also has a 2.7 inch LCD and offers interval shooting, HD video recording and a digital panorama mode.
Jump to:
PENTAX Optio WS80
A go-anywhere, waterproof digital compact camera coupling a compact, lightweight body with underwater-shooting capabilities
August 5, 2009: HOYA CORPORATION PENTAX Imaging Systems Division is pleased to announce the launch of the PENTAX Optio WS80 digital compact camera. The combination of a compact, lightweight body and outstanding waterproof and dustproof capabilities makes the new Optio WS80 an ideal choice for casual, day-to-day applications, including a variety of outdoor activities.
Within its compact body, the Optio WS80 offers a number of advanced, user-friendly features. These include: the assurance of high-quality, high-resolution image reproduction thanks to 10.0 effective megapixels; an optical 5X zoom lens; a large 2.7 inch LCD monitor; HDTV-proportioned movie recording; and a state-of-the-art Face Recognition function. Its airtight body also allows underwater photography to a depth of 1.5 meters for up to two hours continuously. This eliminates worries in situations where water or dirt can be a concern, such as outdoor events, in the garden or kitchen, or on a rainy day.
Major Features
Exceptional waterproof performance for worry-free underwater shooting
Despite its compact, palm-sized body, the Optio WS80 assures reliable waterproof performance conforming to IPX 8 (or JIS Class 8) standards, allowing underwater photography at a depth of 1.5 meters for up to two hours continuously.
It also features the PENTAX-exclusive, highly water-repellent SP (Super Protect) coating on the protective glass element installed at the front end of the zoom lens. As a result, the Optio WS80 can be simply rinsed clean with fresh water if it becomes covered with dirt or sand. Coupled with remarkable dustproof capabilities equivalent to JIS Class 6, the Optio WS80 can be used without worry in many different situations where water or dirt can be a major concern, including water and winter sports.
High-speed Face Recognition, with a range of user-friendly features
The Optio WS80's advanced Face Recognition AF & AE function comes in handy for casual shooting of people. This user-friendly function not only captures 32 faces in sharp focus and perfect exposure in a mere 0.03 seconds, but can even accurately detect a subject standing diagonally to the camera, or one with a tilted head.
The Optio WS80 also offers other user-friendly features, including: the Small Face filter, which makes the subject's face appear smaller in proportion to the body than it actually is, to produce attractive, well-balanced portraits; the Smile Capture mode, which automatically releases the shutter the moment the camera detects the subject's smile; and the Blink Detection function, which warns the photographer when the subject's eyes close at the time of shutter release.
High-performance optical 5X zoom lens
Despite its compact dimensions, the Optio WS80 features an optical 5X zoom lens covering focal lengths from 35mm to 175mm in the 35mm format. It also offers the Intelligent Zoom function, which extends the zoom range up to approximately 28.5 times for even tighter zooming in on the subject.
Triple anti-shake protection to prevent different types of camera shake
Pixel Track SR mode
When recording still images, the Optio WS80's new Digital SR (Shake Reduction) mode effectively compensates for camera shake by processing affected images.
High-Sensitivity SR mode*
When it detects low-lighting conditions in still-image shooting, the Optio WS80 automatically raises its sensitivity to as high as ISO 6400, making it possible to use a higher shutter speed. This effectively minimizes the adverse effects of camera shake and subject shake under poor lighting conditions.
Movie SR mode**
During movie recording, the Optio WS80 prevents blurry images by effectively minimizing annoying camera shake through the use of exclusive software.
High-quality HDTV-proportioned movie recording
The Optio WS80 captures beautiful, flawless movie clips at 16:9 high-definition TV proportions (1280 x 720 pixels)*** at a frame rate of 30 frames per second. It also comes equipped with advanced, user-friendly features designed to facilitate movie recording: the Movie SR (Shake Reduction) mode, which automatically compensates camera shake during movie shooting; and the Underwater Movie mode, which automatically optimizes all camera settings for underwater movie shooting.
High-quality images delivered by 10.0 effective megapixels
Combining approximately 10.0 effective megapixels with the PENTAX-developed imaging engine and high-performance PENTAX zoom lens, the Optio WS80 allows the user to produce brilliant, high-resolution prints with edge-to-edge sharpness, even when images are enlarged to larger sizes.
Large 2.7 inch LCD monitor for effortless image viewing
Despite its compact body, the Optio WS80 features a large 2.7 inch high-brightness color LCD monitor, which allows the photographer to view on-screen images and menus with great comfort and facilitates mode-setting and other camera operations — during both shooting and playback.
Other features
- Interval shooting mode, convenient for fixed-point observation of starry skies, flowers and plants
- High-speed AF system, with Auto-Tracking function, to maintain constant focus on a moving subject
- Auto Picture mode, to automatically select one of the eight shooting modes for the optimum result
- A variety of digital filters, including Toy Camera and Retro, to add distinctive visual effects to recorded images
- D-Range setting, to prevent whitewashed (overexposed) and blacked-out (underexposed) areas in images
- Digital Wide function, to create a panoramic, extra-wide-angle image (equivalent to an image taken with an approx. 25.4mm lens in 35mm format) from two images
- Digital Panorama mode, to create a single panoramic picture from as many as three images
- Style Watch function, to display the time with pushbutton operation, even when the camera's power is turned off
- Image recovery function, to recover accidentally erased images
- Frame composite function (with 90 frames stored in the camera) to shoot or compose images with decorative photo frames
* When the High-Sensitivity SR mode is selected, the recorded size is fixed to 5M (2592 x 1944 pixels).
** When the Movie SR mode is selected, the angle of view becomes narrower than normal shooting.
*** When the Optio WS80's AV output terminal is used, movie clips are output as normal image-size data. If the user wishes to play back movie clips at high-definition-TV proportions (1280 x 720 pixels), the data must be transferred to a personal computer for playback.
Pentax Optio WS80 specifications
* Recording capacity shows approximate number of shots recorded during CIPA-compliant testing. Actual performance may vary depending on operating conditions.
** According to the result of PENTAX in-house testing.


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Pilot Study of rhBMP/BCP With or Without the TSRH® Spinal System for Posterolateral Lumbar Fusion in Patients With Degenerative Disc Disease
This study has been completed.
Medtronic Spinal and Biologics
Information provided by (Responsible Party):
Medtronic Spinal and Biologics
ClinicalTrials.gov Identifier:
First received: December 12, 2011
Last updated: August 1, 2013
Last verified: December 2011
- Full Text View
- Tabular View
- No Study Results Posted
- Disclaimer
- How to Read a Study Record
The purpose of this pilot clinical trial is to evaluate both device designs (rhBMP-2/BCP and rhBMP-2/BCP/TSRH® spinal System) as methods of facilitating spinal fusion as compared to instrumented fusion with autograft in patients with symptomatic degenerative disc disease.
Condition | Intervention |
Degenerative Disc Disease |
Procedure: rhBMP-2/BCP Device: rhBMP-2/BCP/TSRH® Spinal System Device: Autograft/TSRH® Spinal System |
Study Type: | Interventional |
Study Design: | Allocation: Randomized Intervention Model: Parallel Assignment Masking: Open Label Primary Purpose: Treatment |
Official Title: | A Pilot Study of Recombinant Human Bone Morphogenetic Protein-2 and Biphasic Calcium Phosphate With or Without the TSRH® Spinal System for Posterolateral Lumbar Fusion in Patients With Symptomatic Degenerative Disc Disease |
Resource links provided by NLM:
Further study details as provided by Medtronic Spinal and Biologics:
Primary Outcome Measures:
- Fusion [ Time Frame: 24 month ]
Fusion is defined as:
- Evidence of bridging trabecular bone.
- No evidence of motion as defined by: a. No more than 3mm difference in translation on the lateral flexion/extension radiographs determined by superimposing the two views, one upon the other; b. Less than 5° difference in angular motion between flexion and extension as seen on the lateral flexion/extension radiographs;
- Absence of radiolucent lines completely through the fusion mass.
- Pain/Disability Status [ Time Frame: 24 month ]The self-administered Oswestry Low Back pain Disability Questionnaire will be used. Success for each individual patient will be defined as pain/disability improvement postoperatively according to the following definition: Preoperative Score - Postoperative Score >= 15
Secondary Outcome Measures:
- Neurological Status Success [ Time Frame: 24 month ]Neurological status will be assessed preoperatively and postoperatively using a comprehensive neurological status scale. Neurological status is based on four types of measurements (sections): motor, sensory, reflexes and straight leg raise.
- Hip (Donor Site) Pain [ Time Frame: 24 month ]
- General Health Status (SF-36) [ Time Frame: 24 month ]
- Pain Status (back pain, leg pain) [ Time Frame: 24 month ]
- Patient Satisfaction [ Time Frame: 24 month ]
- Patient Global Perceived Effect [ Time Frame: 24 month ]
- Overall Success [ Time Frame: 24 month ]
Enrollment: | 27 |
Study Start Date: | May 1999 |
Study Completion Date: | March 2003 |
Primary Completion Date: | March 2003 (Final data collection date for primary outcome measure) |
Arms | Assigned Interventions |
Experimental: rhBMP-2/BCP |
Procedure: rhBMP-2/BCP
The rhBMP-2/BCP device component consists of recombinant human Bone Morphogenetic Protein-2 ( rhBMP-2) and the biphasic calcium phosphate (BCP) carrier.
Other Names:
Experimental: rhBMP-2/BCP/TSRH® Spinal System |
Device: rhBMP-2/BCP/TSRH® Spinal System
rhBMP-2/BCP device will be used in conjunction with the posterior spinal fixation system, the TSRH® Spinal System.
Other Names:
Active Comparator: Autograft/TSRH® Spinal System |
Device: Autograft/TSRH® Spinal System
The control device will be autogenous bone from the iliac crest of the patient used in conjunction with the TSRH® spinal System.
Other Name: Autograft
Ages Eligible for Study: | 18 Years and older (Adult, Senior) |
Sexes Eligible for Study: | All |
Accepts Healthy Volunteers: | No |
Inclusion Criteria:
Has degenerative disc diseases noted by back pain of discogenic origin,with or without leg pain, with degeneration of the disc confirmed by patient history ( e.g., pain [leg, back, or symptoms in the sciatic nerve distribution] function deficit and/or neurological deficit) and radiographic studies ( e.g., CT, MRl, X-Ray,etc.) to include one or more of the following:
- instability (defined as angular motion > 5° and/or translation > 4 mm, based on Flex/Ext radiographs);
- osteophyte formation;
- decreased disc height;
- thickening of ligamentous tissue;
- disc degeneration or herniation; and/or
- facet joint degeneration.
- Has preoperative Oswestry score > 30.
- Has no greater than Grade 1 spondylolisthesis utilizing Meyerding's Classification (Meyerding HW,1932.).
- Requires fusion of a single level disc space from L1 to S1.
- Is at least 18 years of age, inclusive, at the time of surgery.
- Has not responded to non-operative treatment ( e.g., bed rest, physical therapy, medications, spinal injections, manipulation, and/or TENS) for a period of at least 6 months.
- If female of child-bearing potential, who is not pregnant or nursing, and who agrees to use adequate contraception for 16 weeks following surgery.
- Is willing and able to comply with the study plan and sign the Patient Informed Consent Form.
Exclusion Criteria:
- Has primary diagnosis of a spinal disorder other than degenerative disc disease with Grade1 or less spondylolisthesis at the involved level.
- Had previous spinal fusion surgical procedure at the involved level.
- Require spinal fusion at more than one lumbar level.
- Has a condition which requires postoperative medications that interfere with fusion, such as steroids.
- Has been previously diagnosed with osteopenia, osteoporosis, or osteomalacia to a degree that spinal instrumentation would be contraindicated.
- Has presence of active malignancy.
- Has overt or active bacterial infection, either local or systemic.
- Is grossly obese, i.e., weight > 40% over ideal for their age and height.
- Has fever ( temperature >101°F oral) at the time of surgery.
- Has a documented titanium alloy allergy or intolerance.
- Is mentally incompetent. If questionable, obtain psychiatric consult.
- Has a Waddell Signs of Inorganic Behavior score of 3 or greater.
- Is a prisoner.
- Is an alcohol and/or drug abuser as defined by currently undergoing treatment for alcohol and/or drug usage.
- Is a tobacco user at the time of surgery.
- Has received drugs which may interfere with bone metabolism within two weeks prior to the planned date of spinal fusion surgery (e.g., NSAIDS, steroids or methotrexate).
- Has a history of autoimmune disease (Systemic Lupus Erythematosus or Dermatomyositis).
- Has a history of hypersensitivity to protein pharmaceuticals (monoclonal antibodies or gamma globulins).
- Has received treatment with an investigational therapy within 28 days prior to implantation surgery or such treatment is planned during the 16 weeks following rhBMP-2/BCP implantation.
- Has received any previous exposure to any/all BMPs of either human or animal extraction.
- Has a history of severe allergy (anaphylaxis).
- Has history of endocrine or metabolic disorder known to affect osteogenesis (e.g., Paget's disease, renal osteodystrophy, Ehlers- Danlos syndrome, or osteogenesis imperfecta).
Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study.
To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below.
For general information, see Learn About Clinical Studies.
No Contacts or Locations Provided
No Contacts or Locations Provided
More Information
Keywords provided by Medtronic Spinal and Biologics:
Additional relevant MeSH terms:
ClinicalTrials.gov processed this record on March 28, 2017
Responsible Party: | Medtronic Spinal and Biologics |
ClinicalTrials.gov Identifier: | NCT01494441 History of Changes |
Other Study ID Numbers: |
Study First Received: | December 12, 2011 |
Last Updated: | August 1, 2013 |
Keywords provided by Medtronic Spinal and Biologics:
lumbar degenerative disc disease |
Additional relevant MeSH terms:
Spinal Diseases Intervertebral Disc Degeneration Bone Diseases Musculoskeletal Diseases |
Calcium, Dietary Bone Density Conservation Agents Physiological Effects of Drugs |
ClinicalTrials.gov processed this record on March 28, 2017


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SWF Converter for Mac enables you to convert SWF movie to various video and audio formats in high quality.
How to Convert SWF to MPEG on Windows/Mac OS
If you have some swf files in hand and want to watch them on video players like QuickTime, Microsoft Media Player, VLC Player or portable device like iPod, iPhone, iPad, you may consider of converting the video format from SWF to MPEG. The MPEG file extension has great compatibility in most of the Media Player and Mobile Device.
A freely efficient way to convert swf to mpeg is using easy-to-use SWF to MPEG Converter. Doremisoft SWF Converter dedicates converting SWF to most of popular video formats like MP4, MPEG, FLV, and WMV and etc. There are SWF Converter for Windows and SWF Converter for Mac for both two kinds of users to convert SWF to MPEG. Users could download them for free trial.
How to Convert SWF to MPEG on Windows/Mac OS
After downloading the SWF Converter needed, you just need to install it by default step-by-step instruction. Taking the windows version for example, the user guide will show you 3 simple steps to convert SWF to MPEG. And the operating procedure is the same as Mac version program. So, this is also available for Mac users
Step 1: Launch SWF Converter and add SWF video to SWF Converter
Import SWF video files to the software by clicking "Select File" button to load SWF files need to convert from your laptop. Meanwhile, you are able to convert online SWF video. Click "Grab" button, the SWF video can be successfully downloaded and shown at the left of the interface, you can view the video at the right interface. Choose the output place to put the SWF video.
Step 2: Customize SWF video if necessary
Click "Crop" button to adjust parameters or crop the image frame of the video to delete the unwanted areas, what's more, you are able to add watermark to videos and adjust the position of watermark.
Step 3: Choose MPEG as Output format
Click "Next" button to the Option interface, choose MPEG as the output format, set the output path, customize output format setting is supported such as adjust Encoder, Sample Rate, Channel, Bit Rate.
Step 4: Start converting SWF to MPEG
Press "Next" and hit "Start" button to begin convert SWF to MPEG. You can stop at anytime to view the converted video.
The Mac version of this program has different product interface. Here is a screenshot of it for your reference:
Video Demo of How to Convert SWF to MPEG
Related Articles
- How to Convert Online SWF Videos to MP4/FLV/MOV/AVI/WMV/MPG/MKV/3GP
- How to Convert SWF to FLV on Windows/Mac OS
- How to Convert SWF to M4V on Windows/Mac OS
- An Easy Way to Convert SWF to Apple TV for Playback
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Thanks for the great SWF to MPEG converter! I have many SWF files and want to watch them on my iPhone 4S. This software works efficiently to help me convert SWF files to MPEG videos.– Reviewed by Kathleen


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Watchdog to probe amputee cash snub
The equal opportunities watchdog will look at the long-running case of a man denied a disability allowance despite losing a leg in an industrial accident, officials said after a meeting yesterday.
It is the second small victory in as many months for amputee Lee Shing-leung, 61, who last month had a welfare payment increased after four years of fruitless efforts to secure disability allowance.
With support from legislator Wong Kwok-hing, Lee yesterday met Josiah Chok Kin-ming, a senior officer with the Equal Opportunities Commission. After the meeting, Wong said: 'The EOC accepted Lee's complaint and promised to take up his case because they, too, thought that the government's decision was unfair to him.'
The 'unfairness' is the definition used by the government to assess claims for disability allowances, requiring the loss of both legs, not just one.
The Social Welfare Department increased payments to Lee last month under the Comprehensive Social Security Assistance programme after a new medical assessment found he merited a higher allowance.
Wong, who has long criticised the government's decades-old definition of a disability, said: 'Lee was diagnosed with mental illness after meeting a psychiatric doctor. Based on the doctor's report, he was granted the allowance.
'Clearly, the government just wants him to stop complaining.'
Lee lost his right leg in an industrial accident in 2007.
He took the government to court after the Social Welfare Department rejected his application for disability allowance. He lost the court case despite winning sympathy from judges over the 'deficient and unsatisfactory' welfare system.
He then lost an attempt to get a judicial review.
A Social Welfare Department official, who is familiar with the case but refused to be named, said the decision came after a change was noticed in Lee's condition, which merited a rise in his welfare payments.
Other people who have lost a leg should not rush to apply for higher dole payments, the official said, since Lee's was an individual case based on proper assessments of his condition.
Wong said it was unjustified for the government to treat a physically disabled person as if they were mentally ill in order to get around an outdated law on disability. He said he plans to mobilise more people who are in Lee's situation to pressure the government to change the law.
'So far, I have received complaints from about 10 victims,' Wong said yesterday. 'I will encourage them to forward their cases to the EOC.'
Lee said: 'I don't know how such [laws] can still exist in Hong Kong, since it is such a developed city.'
Many people registered as physically disabled in Hong Kong cannot get a disability allowance because of an outdated law that grants funds only to the most severely disabled.
The number of physically disabled people registered in Hong Kong. Many can't get a disability allowance because of an outdated law


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NEW YORK (AP, TOLEDO NEWS NOW) - President Barack Obama's re-election campaign has released a new television ad and web page pushing back at Republican Mitt Romney's effort to use some of Obama's words against him.
Romney has taken Obama to task for saying "you didn't build that" in a campaign speech about how government helps small businesses thrive. Romney's campaign is running ads that suggest Obama doesn't think entrepreneurs build their own businesses.
Read about a "We Build This" event happening in Holland, Ohio that supports Romney.
The new Obama ad features the president speaking directly to the camera. He says the Romney ads take his words out of context and, the president says, are "flat out wrong."
Obama says he was referring to public programs like education and infrastructure that helped businesses be successful. View a portion of the speech including the quote used by Romney.
At the town hall in Iowa, Obama said, "Someone helped to create this unbelievable American system that we have that allowed you to thrive. Somebody invested in roads and bridges. If you've got a business, you didn't build that. Somebody else made that happen. The internet didn't get invented on its own. Government research created the internet so that all the companies could make money off the internet."
The ads are running in several general-election battleground states including Virginia, North Carolina, Florida, Ohio, Iowa and Nevada.
Copyright 2012 The Associated Press and Toledo News Now. All rights reserved.
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The New Jersey Nets publicly declared that they were no longer in the "Melo Sweepstakes," the organization decided to move on and get over trying to acquire the All-Star forward. The current Nets team responded by handing the Utah Jazz their 2nd consecutive loss, the Nets beat the Jazz 103-95. Seven out of the nine players that played for New Jersey scored in double-figures, Brook Lopez and Devin Harris combined for 34 points. New Jersey jumped out early in the first quarter, the Jazz won the 2nd quarter, but they allowed the Nets to get a big jump on them early in the 3rd and the Nets never relinquished the lead. Utah has now lost two games to teams that have yet to hit 15 wins for the season. If you are an aspiring playoff team how do you lose to the Wizards and the Nets consecutively?? Utah once again was led by their All-World PG Deron Williams, Williams had little help outside of Al Jefferson. Williams had 20 points, 10 dimes, 5 rebounds, and 3 steals. Jefferson chipped in with 21 points and 8 rebounds, Andrei Kirilenko contributed as well with 17 points and 8 rebounds, and CJ Miles had 13 points off the bench for Utah. Memeht Okur had 8 points during his 16 minutes of play, you would think that the Jazz turned the ball over often to loose to the Nets. That wasn't the case at all, the Jazz lost because they shot terrible and they couldn't stop the Nets from putting the ball in the basket. Utah shot 41.6% as a team and 35.7% from beyond the arch, New Jersey on the other hand shot 49.3% as a team and an outstanding 50% from three. Utah got beat on the boards once again, this time they were out-rebounded 44-31! The only positive thing for Utah after loosing this game is that the Thunder have lost their last 2 game as well so they remained tied atop the division. It doesn't get any easier for the Jazz as they visit the Boston Celtics on Friday. Hopefully the thought of playing a better team will help the Jazz raise their own level of play, we shall see. Otherwise the Jazz might be in the midst of a 3 game slide, right now it's only at 2 and I hope they leave it that way when Friday's game is over!!
About the Author
Written by Wilson Tarpeh Jr.
I am a passionate sports fan, who desires a job in the sports industry. I'm a graduate of the Connecticut School of Broadcasting and I have my own website as well. I believe that I have a unique view of sports and I wish to share it with as many people as I can. I hope you enjoy my work.


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Alternative Title:
"De Jure Belli ac Pacis"
Learn about this topic in these articles:
discussed in biography
While in Paris, Grotius published his legal masterpiece,
De Jure Belli ac Pacis, in 1625. In writing this work, which made full use of
De Jure Praedae, he was strongly influenced by the bitter, violent political struggles both in his own country and in Europe more broadly, particularly the Thirty Years' War, which had broken out in 1618. In one famous passage of...
European history
A European identity took shape in the work of Hugo Grotius, whose
De Jure Belli et Pacis (1625;
On the Law of War and Peace) was a plea for the spirit of law in international relations. It gained substance in the work of the great congresses (starting with those of Münster and Osnabrück before the Peace of Westphalia in 1648) that met not only to determine rights and...
...were crucial. In place of the moral vacuum in which the single reality was the power of the individual ruler, there had come into being a body of law, articulated preeminently by Hugo Grotius in
On the Law of War and Peace. It was grounded not only in proven principles of private law but also in the Christian spirit, though it was strengthened by Grotius' separation of natural law from...
influenced by
...law as well as the civil law whenever it suited his purpose. The Dutch jurist Hugo Grotius, in writing the much better-known
De Jure Belli ac Pacis (1625;
On the Law of War and Peace), drew extensively on Gentili's work.
...of a philosophy of public law based upon a study of human nature, Stoic elements are found in the
Utopia (1516), by Thomas More, and the
De Jure Belli ac Pacis (1625;
On the Law of War and Peace), by Hugo Grotius. This latter work is one of the most famous Renaissance treatises on the theory of natural and social rights.
legal theories
...grounded in state law, feudal law, and the question of the general reasonableness of agency had to be overcome. Hugo Grotius in his best-known work,
De Jure Belli ac Pacis (1625;
On the Law of War and Peace), explained that on the basis of his mandate a
procurator could acquire rights directly for his principal. He thereby overcame the Roman rule that allowed...
conduct of war
...were not controlled by any similar concern.) In the Middle Ages in Europe the precepts of Christianity began to provide vague guidelines of conduct on the battlefield. In 1625 Hugo Grotius wrote
On the Law of War and Peace (
De Jure Belli ac Pacis), in which he explored the basic principles of the humanitarian treatment of the victims of war.
...developed in the later European Middle Ages and have undergone continual development in order to meet the needs of the major maritime powers. In his
De jure belli ac pacis (1625;
On the Law of War and Peace), Hugo Grotius took note of a long-standing controversy in regard to what categories of cargo might be confiscated in the same way as weapons. He suggested a threefold...
international law
...During the Thirty Years' War, innovations occurred in the theory and practice of international relations. In 1625 the Dutch jurist Hugo Grotius published
De Jure Belli ac Pacis (
On the Law of War and Peace), in which the laws of war were most numerous. Grotius deplored the strife of the era, which had undermined the traditional props of customary and canon law. In an...
...law has perhaps been exaggerated. Grotius excised theology from international law and organized it into a comprehensive system, especially in
De Jure Belli ac Pacis (1625;
On the Law of War and Peace). Grotius emphasized the freedom of the high seas, a notion that rapidly gained acceptance among the northern European powers that were embarking upon extensive...
...Grotius (1583–1645), to write a defense of their trading rights and their free access to the seas, and the resulting two treatises,
The Freedom of the Seas (1609) and
On the Law of War and Peace (1625), were the first significant codifications of international law. Their philosophical originality lay, however, in the fact that, in...
just war
...legitimate wars must be openly declared, have a just cause, and be conducted justly. The Dutch jurist Hugo Grotius (1583–1645) maintained in
De Jure Belli ac Pacis (1625;
On the Law of War and Peace) that war is justifiable only if a country faces imminent danger and the use of force is both necessary and proportionate to the threat.
prisoners of war
...philosophers expressed their thoughts about the amelioration of the effects of capture upon prisoners. The most famous of these, Hugo Grotius, stated in his
De jure belli ac pacis (1625;
On the Law of War and Peace) that victors had the right to enslave their enemies, but he advocated exchange and ransom instead. The idea was generally taking hold that in war no destruction of...


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Abyssal Shelf
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The Abyssal Shelf is a tilted stretch of land at the northeastern edge of Hellfire Peninsula. It is heavily populated by elite fel reavers, gan'arg and mo'arg soldiers. This area is often the subject of aerial "bombing runs" to destroy the servants of the Burning Legion stationed there.
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Java Draw Created Jul 13, 2012 1024 x 736px Unless noted Copyright 2012 VirusX.
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i love how his hair is so layered and how you can clearly see his expression! 5/5!
I love how your lines look so simple and clean cut, yet if I tried to do that it'd be extremely complicated for me, an probably messy.


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The WIPO has just dropped me an email to say that Azerbaijan and Benin have signed the WIPO Copyright and Performances and Phonograms Treaties. No doubt their games software, film, recording and music industries are uncorking the champagne. Can't be bad for Hollywood or Silicon Valley either can it? For those interested in IPR and developing countries, I can't recommend too highly the excellent website Intellectual property Watch and the materials on intellectual property published by the Quaker United Nations Office in Geneva.
I should also point to a couple of posts on my other blog.
First, the magnificent Steph Aldred of Bmedi@ has published all the presentations and notes given by Janet Bray, Lucas Bateman and Ian Lewis together with my introduction and notes for the talk "Everything that a Bmedi@ Member needs to know about IP at the Outset" that we gave in Bradford on 19 Jan 2006 on her website.
Secondly, the Patent Office has published its opinion on EP(UK) 0801532 which I have already mentioned more than once in this blog. The request was made by my drinking pal Chris Hemingway of Bailey Walsh LLP who has been emboldened to make a second application (see EP0570903 Miter Saw). Bailey Walsh are soon going to corner the market for this sort of application, taking even more bread out of the mouths of patent litigators. Chris has kindly agreed to chair the next meeting of the Leeds Inventors Club which will be addressed by Dai Davis. That should be a treat for what Dai doesn't know about the topic he has chosen you could write on the back of a non-commemorative postage stamp (see "Leeds Inventors Club: You can always say Dai").


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Findings from both studies were presented in oral sessions at the 54th annual meeting of the American Society of Hematology (ASH) in Atlanta.
Two-year results from ENESTcmr showed that switching to Tasigna led to deeper molecular responses** in patients who still had evidence of residual disease after long-term therapy with Gleevec1. More than twice as many patients treated with Tasigna continued to achieve undetectable BCR-ABL versus Gleevec. The difference between groups by 24 months was statistically significant (22.1% vs. 8.7%; p=0.0087) and that difference has doubled since the 12-month analysis. Significantly more patients treated with Tasigna achieved MR4.5 or undetectable BCR-ABL versus Gleevec regardless of the BCR-ABL transcript level at baseline1. In studies published to date, no patients achieving and maintaining MR4.5 have progressed to advanced stages of CML2,3,4,5,6.
"Tasigna should be considered as a leading option for frontline therapy because it allows many patients to achieve deeper responses earlier, which we have associated with improved long-term outcomes," said Timothy P. Hughes, MD, ENEST study investigator, Head of the Department of Haematology at Royal Adelaide Hospital and Clinical Professor at the University of Adelaide, Australia.
Also presented at ASH are the results of a four-year landmark analysis from ENESTnd which showed that more than three times as many patients achieved early molecular response (reduction in BCR-ABL transcript levels to less than or equal to 10% at months three and six) with Tasigna as frontline therapy instead of Gleevec7. The investigators correlated early molecular response with future major molecular response (MMR) and MR4.5, as well as an increased probability of progression-free survival and overall survival7.
In a separate four-year analysis of efficacy and safety data from ENESTnd also presented at ASH, the difference in the rates of both MR4 and MR4.5 continued to be significantly higher for Tasigna, with the difference in favor of Tasigna increasing over time (MR4: 9-14% difference by one year, 17-24% difference by four years; MR4.5: 6-10% difference by one year, 14-17% difference by four years)7. Overall survival remained similar in all groups at four years, but fewer CML-related deaths occurred in both the Tasigna 300 mg twice daily (n=5) and 400 mg twice daily (n=4) arms versus Gleevec (n=13)7.
"We are encouraged by the continued strong findings from newly-presented CML data at ASH," said Herve Hoppenot, President, Novartis Oncology. "Our dedication to ongoing research in CML over the past decades has helped to transform the disease from a fatal diagnosis to a chronic condition. We are now starting the next chapter in our commitment to helping patients with this disease by exploring in Tasigna clinical trials the idea that some patients may be able to safely stop therapy after achieving sustained and deep molecular response."
Novartis Commitment to CMLNovartis Oncology helped pioneer the transformation of Ph+ CML to a treatable, chronic condition. As an industry leader in CML, Novartis is committed to furthering the understanding of this disease and to redefining once again what is possible for the future of Ph+ CML. The company plans to initiate in early 2013 a robust clinical trial program evaluating the possibility of treatment-free remission in CML, which means sustaining deep molecular response after stopping therapy. Nine treatment-free studies are planned to be conducted in study centers across more than 50 countries.
Worldwide, CML is responsible for a little over 10% of all adult cases of leukemia, with an incidence of one to two cases per 100,000 people per year8,9.
ENESTcmr study detailsENESTcmr (Evaluating Nilotinib Efficacy and Safety in Clinical Trials Complete Molecular Response) is an open-label, randomized, prospective, multi-center Phase III study of Tasigna 400 mg twice daily versus standard-dose Gleevec (400 mg or 600 mg once daily) comparing kinetics of molecular response for patients with Ph+ CML in chronic phase who had achieved complete cytogenetic response (CCyR) but were still BCR-ABL positive (i.e., had evidence of residual leukemia) after at least two years of treatment with Gleevec. The study enrolled 207 patients. The patients were randomized into one of two treatment arms: Tasigna 400 mg twice daily versus continuing Gleevec 400 mg or 600 mg once daily (same dose as at study entry)1.
The primary endpoint was the rate of confirmed best complete molecular response by 12 months of study therapy with Tasigna or Gleevec. Secondary objectives included the kinetics of molecular response, duration of molecular response, progression-free survival and overall survival in both arms. These data, presented at ASH, were the 24-month follow-up1.
More than twice as many patients treated with Tasigna continued to achieve undetectable BCR-ABL versus Gleevec. The difference between groups by 24 months was statistically significant (22.1% vs. 8.7%; p=0.0087). Compared to the 12-month analysis, the difference between the treatment arms doubled over time from 6.7% to 13.4%. Among patients without documented MR4.5 at baseline, cumulative incidence of MR4.5 was over twice as high in Tasigna-treated patients versus those who stayed on Gleevec (42.9% vs. 20.8%; p=0.0006) and the difference increased over time from 12 to 24 months. Significantly more patients treated with Tasigna achieved MR4.5 versus Gleevec regardless of the BCR-ABL transcript level at baseline. In patients without documented MMR, MR4 and MR4.5 at baseline, the differences were superior in all subsets (29.2% vs. 3.6%; p=0.016; 31.1% vs. 11.5%; p=0.003 and 42.9% vs. 20.8%; p=0.0006, respectively)1.
ENESTnd study detailsENESTnd (Evaluating Nilotinib Efficacy and Safety in Clinical Trials Newly Diagnosed Patients) is a Phase III randomized, open-label, multicenter trial comparing the efficacy and safety of Tasigna versus Gleevec in adult patients with newly diagnosed Ph+ CML in chronic phase. It is the largest global randomized comparison of two oral therapies ever conducted in newly diagnosed Ph+ CML patients7,10,11.
The study is being conducted at 217 global sites with 846 patients enrolled. Patients were randomized to receive Tasigna 300 mg twice daily (n=282), Tasigna 400 mg twice daily (n=281) or Gleevec 400 mg once daily (n=283). The primary endpoint was major molecular response (MMR) at 12 months; the key secondary endpoint was durable MMR at 24 months (patients having MMR when evaluated at both 12 and 24 months). MMR was defined in this study as 0.1% or less of BCR-ABL as measured by RQ-PCR. Planned follow-up is for five years. Patients on the Gleevec treatment arm who had suboptimal response or treatment failure were allowed to escalate dose and/or switch to Tasigna in a separate extension study. These data, presented at ASH, were the 48-month minimum follow-up7,10,11.
The ENESTnd landmark analysis was based on BCR-ABL transcript levels at three and six months using data with a minimum follow-up of four years. The Tasigna 300 mg BID (n=282) and Gleevec 400 mg QD (n=283) treatment arms were used for the analysis. Rates of MMR, MR4.5, progression-free survival and overall survival were evaluated among patients grouped according to their BCR-ABL transcript levels of less than or equal to 1%, >1% to less than or equal to 10%, and >10% at three and six months. Among evaluable patients at three months, 9% of patients (n=24) in the Tasigna arm versus 33% (n=88) in the Gleevec arm had BCR-ABL transcript levels of >10%. Patients with a BCR-ABL transcript level of >10% had a significantly lower probability of future MMR or MR4.5as well as poorer progression-free survival and overall survival compared with patients who had BCR-ABL transcript levels less than or equal to 10% at three months. Fewer patients in the Tasigna arm versus the Gleevec arm had BCR-ABL transcript levels >10% at three and six months. Early molecular response at three and six months correlated with future MMR and MR4.5as well as an increased probability of progression-free survival and overall survival7.
The four-year ENESTnd update found continued significantly higher rates of MMR, MR4 and MR4.5by three years were achieved in Tasigna versus Gleevec-treated patients. The difference in the rates of both MR4 and MR4.5continued to be significantly higher for Tasigna, with the difference in favor of Tasigna increasing from year one to year four (MR4: 9-14% difference by one year, 17-24% difference by four years; MR4.5: 6-10% difference by one year, 14-17% difference by four years). Among patients who achieved MMR, more patients achieved MR4 or MR4.5on Tasigna 300 mg twice daily (68%) and Tasigna 400 mg twice daily (62%) compared with Gleevec (49%). No patient in any arm progressed after achieving MR4.5. Significantly fewer patients progressed to accelerated phase/blast crisis on Tasigna versus Gleevec. Nearly twice as many patients had emergent mutations on Gleevec (n=21) versus either Tasigna arm (n=11 in each arm), with five patients overall developing mutations between two and three years. Overall survival remained similar in all groups at three years, but fewer CML-related deaths occurred in both the Tasigna 300 mg twice daily (n=5) and 400 mg twice daily (n=4) arms versus Gleevec (n=14). Both drugs were well tolerated. Few new adverse events (AEs) and laboratory abnormalities were observed between two and three years. Rates of discontinuation due to AEs were 10%, 14%, and 11% in the Tasigna 300 mg BID, Tasigna 400 mg BID, and Gleevec arms, respectively11.
About TasignaTASIGNA® (nilotinib) is approved for the treatment of adult patients with newly diagnosed Philadelphia chromosome-positive chronic myeloid leukemia (Ph+ CML) in chronic phase. The effectiveness of TASIGNA for this indication is based on major molecular response and cytogenetic response rates at 12 months. The study is ongoing and further data will be required to determine long-term outcome.
TASIGNA is also approved in more than 90 countries for the treatment of chronic phase and accelerated phase Ph+ CML in adult patients resistant or intolerant to at least one prior therapy, including Gleevec. The effectiveness of TASIGNA for this indication is based on hematologic and cytogenetic response rates.
BOXED WARNING and Important Safety Information for TASIGNA (nilotinib):
WARNING: QT PROLONGATION AND SUDDEN DEATHSTASIGNA prolongs the QT interval. Prior to TASIGNA administration and periodically, monitor for hypokalemia or hypomagnesemia and correct deficiencies. Obtain ECGs to monitor the QTc at baseline, seven days after initiation, and periodically thereafter, and follow any dose adjustments. Sudden deaths have been reported in patients receiving nilotinib. Do not administer TASIGNA to patients with hypokalemia, hypomagnesemia, or long QT syndrome. Avoid use of concomitant drugs known to prolong the QT interval and strong CYP3A4 inhibitors.Patients should avoid food 2 hours before and 1 hour after taking dose.
Treatment with TASIGNA can cause Grade 3/4 thrombocytopenia, neutropenia, and anemia. Complete blood counts should be performed every 2 weeks for the first 2 months and then monthly thereafter.
Caution is recommended in patients with a history of pancreatitis.
The use of TASIGNA may result in elevations in bilirubin, AST/ALT, and alkaline phosphatase.
TASIGNA can cause hypophosphatemia, hypokalemia, hyperkalemia, hypocalcemia, and hyponatremia (see Boxed WARNING).
The concomitant use of strong CYP3A4 inhibitors or anti-arrhythmic drugs (including, but not limited to, amiodarone, disopyramide, procainamide, quinidine, and sotalol) and other drugs that may prolong the QT interval (including, but not limited to, chloroquine, clarithromycin, haloperidol, methadone, moxifloxacin, and pimozide) should be avoided. Grapefruit products should also be avoided.
The concomitant use of strong CYP3A4 inducers should be avoided (including, but not limited to, dexamethasone, phenytoin, carbamazepine, rifampin, rifabutin, rifapentin, phenobarbital, and St. John's wort).
TASIGNA must not be taken with food.
TASIGNA exposure is increased in patients with impaired hepatic function.
Cases of tumor lysis syndrome have been reported in TASIGNA treated patients with resistant or intolerant CML. Due to potential for tumor lysis syndrome, maintain adequate hydration and correct uric acid levels prior to initiating therapy with TASIGNA.
The exposure of TASIGNA is reduced in patients with total gastrectomy.
Since the capsules contain lactose, TASIGNA is not recommended for patients with rare hereditary problems of galactose intolerance, severe lactase deficiency with a severe degree of intolerance to lactose-containing products, or of glucose-galactose malabsorption.
Women of childbearing potential should avoid becoming pregnant while taking TASIGNA and should be advised of the potential hazard to the fetus if they do. The safety and effectiveness of TASIGNA in pediatric patients have not been established.
In newly diagnosed Ph+ CML-chronic phase, the most commonly reported nonhematologic adverse drug reactions (>10%) were rash, pruritus, headache, nausea, fatigue, and myalgia.
In resistant or intolerant Ph+ CML-chronic phase, the most commonly reported nonhematologic adverse drug reactions (greater than or equal to 10%) were rash, pruritus, nausea, fatigue, headache, constipation, diarrhea, vomiting, and myalgia.
In resistant or intolerant Ph+ CML-accelerated phase, the most commonly reported nonhematologic adverse drug reactions (greater than or equal to 10%) were rash, pruritus, and fatigue.
TASIGNA may need to be temporarily withheld and/or dose reduced for QT prolongation, hematologic toxicities that are not related to underlying leukemia, clinically significant moderate or severe nonhematologic toxicities, laboratory abnormalities, or concomitant use of strong CYP3A4 inhibitors.
Please see full Prescribing Information including Boxed Warning.
About GleevecGleevec® (imatinib mesylate) tablets are indicated for newly diagnosed adult patients with Philadelphia chromosome-positive chronic myeloid leukemia (Ph+ CML) in the chronic phase (CP). Gleevec is also indicated for the treatment of patients with Ph+ CML in blast crisis (BC), accelerated phase (AP), or in CP after failure of interferon-alpha therapy.
GLEEVEC Important Safety InformationGLEEVEC can cause fetal harm when administered to a pregnant woman. Women should not become pregnant, and should be advised of the potential risk to the unborn child.
GLEEVEC is often associated with edema (swelling) and serious fluid retention. Studies have shown that edema (swelling) tended to occur more often among patients who are 65 and older or those taking higher doses of GLEEVEC.
Cytopenias (reduction or lack of certain cell elements in blood circulation), such as anemia, have occurred. If the cytopenia is severe, your doctor may reduce your dose or temporarily stop your treatment with GLEEVEC.
Severe congestive heart failure and left ventricle dysfunction have been reported, particularly in patients with other health issues and risk factors. Patients with heart disease or risk factors or history of renal failure will be monitored and treated for the condition.
Severe liver problems (hepatotoxicity) may occur. Cases of fatal liver failure and severe liver injury requiring liver transplants have been reported with both short-term and long-term use of GLEEVEC.
Bleeding may occur. Severe gastrointestinal (GI) bleeding has been reported in patients with KIT+ GIST. GI tumor sites may be the cause of this bleeding; therefore, GI symptoms should be monitored at the start of treatment.
In patients with hypereosinophilic syndrome (a condition with increased eosinophils, which are a type of white blood cell) and heart involvement, cases of heart disease (cardiogenic shock/left ventricular dysfunction) have been associated with the initiation of GLEEVEC therapy.
Skin reactions, such as fluid-filled blisters, have been reported with the use of GLEEVEC.
Clinical cases of hypothyroidism (reduction in thyroid hormones) have been reported in patients taking levothyroxine replacement with GLEEVEC.
Long-term use may result in potential liver, kidney, and/or heart toxicities; immune system suppression may also result from long-term use.
GI perforation (small holes or tears in the walls of the stomach or intestine), in some cases fatal, has been reported.
Growth retardation has been reported in children taking GLEEVEC. The long-term effects of extended treatment with GLEEVEC on growth in children are unknown.
Cases of tumor lysis syndrome (TLS), which refers to a metabolic and electrolyte disturbance caused by the breakdown of tumor cells, have been reported and can be life-threatening in some cases. Correction of clinically significant dehydration and treatment of high uric acid levels are recommended prior to initiation of GLEEVEC.
Reports of motor vehicle accidents have been received in patients receiving GLEEVEC. Caution patients about driving a car or operating machinery.
Almost all patients treated with GLEEVEC experience side effects at some time. Some common side effects you may experience are fluid retention, muscle cramps or pain and bone pain, abdominal pain, loss of appetite, vomiting, diarrhea, decreased hemoglobin, abnormal bleeding, nausea, fatigue and rash.
GLEEVEC is sometimes associated with stomach or intestinal irritation. GLEEVEC should be taken with food and a large glass of water to minimize this problem. There have been rare reports, including deaths, of stomach or intestinal perforation (a small hole or tear).
If you are experiencing any of the mentioned side effects, please be sure to speak with your doctor immediately.
Do not take any other medications without talking to your doctor or pharmacist first, including Tylenol® (acetaminophen); herbal products (St. John's wort, Hypericum perforatum); Coumadin® (warfarin sodium); rifampin; erythromycin; metoprolol; ketoconazole; and Dilantin® (phenytoin). Taking these with GLEEVEC may affect how they work, or affect how GLEEVEC works.
You should also tell your doctor if you are taking or plan to take iron supplements. Patients should also avoid grapefruit juice and other foods that may affect how GLEEVEC works.
Please see full Prescribing Information.
Disclaimer The foregoing release contains forward-looking statements that can be identified by terminology such as "planned," "expected," "will," "potential," "can," "may," "would," "recommend," "expected," or similar expressions, or by express or implied discussions regarding potential new business opportunities. You should not place undue reliance on these statements. Such forward-looking statements reflect the current views of management regarding future events, and involve known and unknown risks, uncertainties and other factors that may cause actual results to be materially different from any future results, performance or achievements expressed or implied by such statements. There can be no guarantee that any such business opportunities will develop in the manner, scale or time frame anticipated. In particular, management's expectations could be affected by, among other things, unexpected regulatory actions or delays or government regulation generally; unexpected clinical trial results, including unexpected new clinical data and unexpected additional analysis of existing clinical data; competition in general; government, industry and general public pricing pressures, and unexpected reimbursement decisions; the company's ability to obtain or maintain patent or other proprietary intellectual property protection; the impact that the foregoing factors could have on the values attributed to the Novartis Group's assets and liabilities as recorded in the Group's consolidated balance sheet, and other risks and factors referred to in Novartis AG's current Form 20-F on file with the US Securities and Exchange Commission. Should one or more of these risks or uncertainties materialize, or should underlying assumptions prove incorrect, actual results may vary materially from those anticipated, believed, estimated or expected. Novartis is providing the information in this press release as of this date and does not undertake any obligation to update any forward-looking statements contained in this press release as a result of new information, future events or otherwise.
About NovartisLocated in East Hanover, New Jersey, Novartis Pharmaceuticals Corporation is an affiliate of Novartis AG, which provides innovative healthcare solutions that address the evolving needs of patients and societies. Headquartered in Basel, Switzerland, Novartis offers a diversified portfolio to best meet these needs: innovative medicines, eye care, cost-saving generic pharmaceuticals, preventive vaccines and diagnostic tools, over-the-counter and animal health products. Novartis is the only global company with leading positions in these areas. In 2011, the Group's continuing operations achieved net sales of USD 58.6 billion, while approximately USD 9.6 billion (USD 9.2 billion excluding impairment and amortization charges) was invested in R&D throughout the Group. Novartis Group companies employ approximately 127,000 full-time-equivalent associates and operate in more than 140 countries around the world. For more information, please visit http://www.novartis.com.
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*Known as Glivec® (imatinib) outside the US, Canada and Israel
**In ENESTcmr, molecular response (reduction of BCR-ABL transcripts in the blood of patients) is measured at four levels, based on an international standard:
SOURCE Novartis