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Viral Load Rebound Rate of 35% Using Ritonavir-Boosted PI Monotherapy: Results of 5-Year PIVOT Study
March 24, 2014
A long-term strategy study sponsored by the Medical Research Council (MRC) in the UK reported low rates of serious complications and the potential to reduce drug costs. However, more than a third of people on the ritonavir-boosted PI monotherapy group had viral load rebound compared to only 3% of people on standard combination therapy.
The PIVOT study randomised 587 UK patients who already had an undetectable viral load on stable treatment to either PI/r monotherapy or triple therapy. It included four years of follow up (median 44 months, maximum 59 months) and the primary endpoints was loss of future treatment options based on development of drug resistance.
Participants in the monotherapy arm were restarted on triple therapy if they had three viral load results >50 copies/mL (including a retested sample), or due to side effects or patient choice. Approximately 80% of people in the boosted PI monotherapy arm used darunavir/r, with 14% using lopinavir/r and 7% using another PI.
Baseline characteristics included median age 44 years (IQR 38-49), 23% women, 60% gay men; 68% white, 28% black, 4% other. Baseline CD4 count and CD4 nadir were 513 cells/mm3 (IQR 392 - 682) and 178 cells/mm3 (IQR 86 - 250), respectively. Median time on ART was 4.0 years (IQR 2.2 - 6.7), having used a median of 4 individual drugs (IQR 3 - 6). Approximately half of participants were using PI-based and half using NNRTI-based treatment at enrolment.
Although loss of treatment options was low in both arms, more people lost treatment options on the PI/r vs the triple therapy arm. These results were 6 (2.1%) vs 2 (0.7%) people [difference 1.4% (95%CI -0.4 to 3.4%), p = 0.15] after 36 months and 6 (2.1%) vs 4 (1.8%) people [difference -0.2% (95%CI -2.5 to 2.46%), p = 0.85] at the end of the trial.
However, viral load rebounded much more frequently in the monotherapy group ( 35% vs 3.2%; difference 31.8% [95%CI 24.5% to 39.0%], p < 0.001). Patients with viral rebound all became undetectable again, either spontaneously or after the addition of two NRTIs.
There were no significant differences between arms by CD4 response (p=0.21), numbers of serious complications (p=0.15) or change in neurocognitive function (change in mean NPZ-score, p=0.86). However, there were less grade 3/4 serious events in the monotherapy group [n=137 vs 159 (46% vs 55%; difference, -8.4%; 95%CI -16.4% to 0.3%), p=0.043].
Although the poster included no details on the higher numbers of deaths in the monotherapy arm (n=6 vs 1), these were apparently largely related to cancers and not attributed to treatment strategy.
Finally, although the results reported overall mean (SE) drug costs of £21,260 (700) vs £30, 230 (860), with the PI/r monotherapy treatment saving £8,970 (-6,790 to -11,160) per person over five years, this did not take account of additional monitoring and costs associated with changing treatment in those patients with viral rebound.
The very high rates of viral rebound in people using PI/r monotherapy makes it unlikely that this study will change prescribing guidelines. Given the volume of data generated from the extensive follow-up it is also frustrating that so little information was included in the poster.
It is unclear why there was no analysis for whether virological failure was related to prior treatment history, choice of boosted PI, adherence (including not taking meds with food), or other factors and it is unclear why details of deaths in the study were not included.
Cost differences based on drug costs alone, rather that as part of a more detailed analysis of total management costs are unhelpful.
A more comprehensive presentation of the results will be presented as an oral session at the upcoming BHIVA conference in Liverpool.
This article was provided by HIV i-Base. It is a part of the publication HIV Treatment Bulletin. Visit HIV i-Base's website to find out more about their activities, publications and services.
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My SciELO
Services on Demand
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Print version ISSN 1990-7451
OSTRIA, Gustavo Rodríguez; SERRANO, Humberto Solares and CANEDO, María Lourdes Zabala. Youth, fear and urban space in Cochabamba.Translated byGustavo Rodríguez Ostria. T'inkazos [online]. 2008, vol.4Selected edition, pp. 0-0. ISSN 1990-7451.
For upper-middle-class young people in the city of Cochabamba, the limits of the habitable world are reached a few blocks away from the Plaza Colón, in the heart of the old city centre. Just metres further on begins an invisible wall that separates two worlds, two cultures and two aesthetics, where fear and insecurity play an important role. In this article, the authors share some of the findings from their research on young people and the decline of the public space in Cochabamba.

subset: commoncrawl


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Seller assumes all responsibility for listing this item. You should contact the seller to resolve any questions before bidding. Currency is USD unless otherwise noted.
2005 Buick LeSabre Custom
Vin# G4HP52KX5U144659 Asset-ID# 58533
Up for sale is a 2005 Buick LeSabre Custom. It has a 3.8L V6 engine. It is in Fair condition. Some decals have been removed but impressions may still remain. Some wires may be exposed due to removal of safety equipment.
Personal inspection of vehicle is recommended before placing bids. All Items are sold As Is/Where Is. Preview of Vehicles: There will be a preview of all items for sale for those who would like to see and do a personal inspection on: Wednesday May 16, 2018 from 10:00AM to 11:00AM. Directions for Preview: From Pensacola, Go North on US 29 to Kingsfield Road. Turn left on Kingsfield Road, you will be heading west on Kingsfield. Go to 4-Way Stop sign and turn Right at county road 297A, you will be heading north on 297A. Go up 1/2 mile on left and turn left in to the Road Department. Park in first parking lot on left, the vehicles are in the fenced lot behind the parking lot. Directions for Payment and Pickup:
All auctions must be paid for and picked up within 3 Business days of close of auction. You must call beforehand to setup time to pay for and pickup items, The Business office is Closed on Friday.
Florida Sales Tax of 7.5% applies to this auction and a 10% Buyer Premium to this sale. If paying in cash please bring the Exact amount of item to the penny, no change will be given. No Personal checks.
The buyer's premium must be paid before pickup of item from Escambia County Surplus Office. You must pay the buyer premium separate from final auction amount owed to Escambia County.
Buyer must be able to Jump start, Tow, and/or Load items purchased. No assistance will be available.
If you have any questions about the vehicle, please call 850-937-2123 Mon-Thur 7:00am to 4:30pm. To insure fairness, and to let all bidders have a chance to place a bid on this item, this auction is setup to go into overtime bidding, and will not close, until no bids have been placed for at least 60 seconds from the last bid placed. Good Luck Bidding and Enjoy the Auction!!!
This listing is closed!This item was re-posted, you can find the new listing athttp://www.pensacolacommunityauction.com/Listings/Escambia-County-Government/1988-International-Box-Truck-ID-54188-1640.php.


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Nandos - Camps Bay
Berg-en-Dal is situated on the bank of the Matjulu Spruit with a view of softly undulating hills to the east. On the northern and southern sides dry riverbeds and a dam border the camp. There are large trees along the streams and dry riverbeds. Special care has been taken to preserve the natural vegetation in the camp. Berg-en-Dal is also the only camp set in a rugged mountain environment and is built on the site of a prehistoric settlements.


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Design board gameemplois
need to create a job board in Joomla. with owner, multiple employers and multiple job seekers. This is a simple job board. It will be based on existing job extension (about 40% of requirements), Joomla user management, article & tag system etc. Frontend and backend UI should be created. It should have very good UX. I shall give requirements and explain
I need a curcuit board designed and a list of components needed so that I can build the circuit myself. I have very little electronic component knowledge and no curcuit building knowledge. This information must be presented to me in an understandable way. The curcuit needing to be built is relatively simple. I need a curcuit that can connect to a motor
I have to develop a board for an embedded display. The display must be 3.5" The board must be based on a STM32 processor (STM32h7 or equivalent would be preferrable) The board must be able to dialogate with other modules with CAN protocoll The board must be turned ON via a message on the CAN protocoll. When the board is OFF it should absorb minimum
Urgent: Looking for someone to conduct a UI design for a website + different storyboards and mock-ups asap
Job board in Joomla UI like Jobboard ([se connecter pour voir l'URL]) UI Jobboard is dead. Do not expect any support for above it. There are joomla extensions which work as job board. Unfortunately they have only 40% useful features for me. They can be used as starting examples.
i need a device driver work with AUDIO CODEC PROTO board(WM8731). Speakers and Mike are connected with the board, and this board is connected with Raspberry pi3. i would like to record & play sound with those.
I need some graphic design of some paddle boards done like attached. Please do not message if you cannot do.
I put Drupal examples. You may suggest me same things in Joomla too. -Job board --Combination of recruiter algo ([se connecter pour voir l'URL]) and UI Jobboard ([se connecter pour voir l'URL]) --recruiter is only security maintenance only --UI Jobboard is dead. --Do not expect any support for above two projects Mobile app or web
I need 3 articles written for my board of education campaign. Research may be needed on the topics. 1. About me - will supply information for this 2. Platform - More and Improved Professional Development for Teachers 3. Platform Idea - We need to hire a grant writer (reasons why and examples of existing grant opportunities)
Our space board game board has been lovingly drawn at full size with pen and paper. A hi-res scan is available for your reference. We need a professional designer to design the game-board in Illustrator using our supplied fonts, colourways, 'mood board' and text. We then need the resulting image to be exported as a print-ready CMYK ima...
There is a small task with assembly programming
I work on the board of a non profit - Foss Waterway Seaport. We are a museum that is mainly funded by people donating. We want to honor those that donate with a live donor board at the museum. We want to include pictures the progression of the building and the names of the donors in a PPT / Keynote / Movie format.
We are a stock listed company in the area of smartphone services and are looking for designer to design our powerpoint presentation for our quarterly board meetings. German language skills needed.
...for a skilled electronic engineer capable to design and prepare for production a PCIe x4 board with dual NIC controller Intel i350. The two SerDes interfaces of the i350 controller should be linked to two 400pin connectors. The 400pin connectors will be used to attach NVidia Jetson TX2 modules to the board. The Jetson TX2 modules will draw power from
I need some one to create a white board drawing video of 3 minutes duration ..
I have a retail flower and garden business and I looking to replace my dated sandwich board signs that will be placed at the sidewalk. We have the wooden structure just need the design to be printed on a grommeted piece of weatherproof foldable/rollable material. Look at [se connecter pour voir l'URL] To get an idea on what we do.
This is a bid for eight (8) pieces which need 3d model files on. No Rendering required for these pieces as they will be used for mass production and allow people to paint them if they choose too. Files will need to be compatible with Blender and also .STL for 3d printer. Each piece will be based on artwork and will be scaled to be approx. 1.5 in (37mm) in height and will be set onto a 1" (...
...specializes in connecting aspiring game designers from around the world to produce and develop high quality board and card games through collaboration for commercial success. We are seeking a slick, modern and mysterious gaming logo that conveys the message of having a tight-knit community from all over the world of game designers who collaborate together
My name is Lilian. I'm the founder of Eli...startup in Kenya that develops innovative teaching and learning resources for children. We have designed an educational board game and we want to make it digital. I'm looking for a very good game developer preferably from India, who can design it for us on a mobile platform. (Removed by Freelancer.com Admin)
...October 17, Canada legalizes the use of recreational cannabis thru governmental And private retailers. Looking for cannabis scientists or medical practitioners to join advisory board to strength cannabis field side of coin, and to offer advice on strains to choose for retail operations once those licenced and for possible strains for production for Italian
I want to initiate a project for creation of a white board animation software similar to other white board animation feature software in market such as videoscribe or doodly. I am also interested in a watered down version of video editing features in software. I would like to know in reply, 1. Which programming language you propose? 2. Which video
We have an LCD with an LVDS interface that we want to drive from an ARM board with 24-bit parallel LCD interface. The board runs on 3.3V for logic levels and power supply. The display uses offset voltages of +20V, -6.8V, +11V that need to be generated. The backlight consists of on string of LEDs that need to be driven at 9.6V with 160-180mA. The parallel
Hi Dear please find attached file of sign board of Shawar Max we need to edit it some need to add below some pictures breakfast , burger ,pizza,shakes 80cm x 550 cm signboard size please we need it today so only bid your original price you put any initial bid and then increase it so please read carefully and see attached files then make bid
HI -You need to be quick and very familiar of how to Backfill and integrate using API or * Widgets for all the positions on our job board using our Zip Recruiter partner. We will send the job board url as we short list. We prefer you can complete this in 3 days or less. Please do not bid if you do not know how to do backfill. Include website references
HI -You need to be quick and very familiar of how to Backfill and integrate using API or * Widgets for all the positions on our job board using our Zip Recruiter partner. We will send the job board url as we short list. We prefer you can complete this in 3 days or less. Please do not bid if you do not know how to do backfill. Include website references
I have designed a unique word game with interesting mechanics never before seen and a unique layout. I am looking for someone to design and print the board using a 3d printer. I will pay for materials and labor.
Need art for board game ,vampires and cleric,mostly grey colors,and art for box.
I am looking for a cover artist for a tabletop card game. The game is about mixing spooky drinks for creepy clientele. It has a cartoonish character style, with slightly more realistic looking glasses and ingredients. Please see attached examples. The cover artwork will be 5 inches wide x 3.5 inches tall at print, although a very high resolution file
I want to make a menu board electronically with graphics that will attract customers to come to my store. The size of the TV is 40 inch
hi. I am going to draw Japanese Johnny West cartoon picture book. Certain content is in the attachment. You need to know a little Japanese. I like this style. [se connecter pour voir l'URL] Thank you very much.
I have a board game concept and I need someone to draw it for me. Things need to be done: - Draw 10 characters for the outside box. - Draw 11 cards, 1 character and 1 animal - Draw the board Please share your previous design, COMMITE WITH YOUR OFFER PRICE.
Need a white board drawing maker
We require a story board artist to work with us to create an animation series like naruto [se connecter pour voir l'URL]
Hi. We need a packaging design for the carton of a wooden board game. We will supply high res images of the toy and a full brief of the texts and elements we need. on each side. We need someone to design all 4 sides of the box and make it look balanced despite the clutter of having everything in 2 languages. So experience with multilanguage artworks
This is a custom-build PCB board that is Arduino-compatible and has SAMD21G18 MCU with another wireless IoT chip. Requirements are to make the Arduino IDE work with the board, modify the Arduino bootloader, and build other drivers for the SAMD21G18 MCU to program the wireless IoT chipset.
I am looking for a creative graphic artist to create a story board for a visual concept store - with logo design product range within the concept. I have attached examples of what I am looking for. The story board needs to be super dynamic and modern. Prospective candidates need to supply samples of their work. Logo will be supplied to successful applicant
I am looking for someone to design and make a PCB board or male to female type c with a 4 wire lead and capability of being recognized by otg.
TeensyPewPew program that emulates a player moving through a series of static and moving blocks. The aim of the player is to move/jump between blocks while gaining points and lives. Knowledge of the Teensy microcontroller is required. Further details will be provided. Deadline: 7 days.
Project Blue Board • Controller board for a hand held fan and light source. • All required information should be provided below, otherwise propose or ask • Critical component locations are indicated Basic control board with following main components: • Battery 3,7V HHS 106070 -5000mAh • Voltage step up from 3,7V to 12V and 24 V Respectively
We will provide story line for 30 white board video, daily one video max 30 seconds , with lady voice ....
Do you like RPGs? Do you like Board Games? Then we need your design expertise. We need a logo for a Gaming Group, who will now start designing and writing books/adventures for role playing game (e.g. Dungeons and Dragons, Pathfinder, Dungeon Crawl Classic, etc..). Reference information (might help generate ideas): Our group is called the Death
i have a story board that must be done in 10 slides i need excellent drawing illustrator to do images with colors i need them tonight my budget is 50$ (if u cant tonight and with my budget please dont apply) same style of the drawing attached the synopsis The ad starts with everything in bright live colors, and the whole setting is very vibrant filled
i have broken the turn on cable after open my laptop, i want know how i can bypass the turn up button? which the best solutiion? look the photo, i can soldering two cable and make direct contact with turn up button?
I need to draw a tv advertising story board I need to have it tmr urgently my budget is 70$ -12 slides
I have a job board site and I am looking to get the jobs listed on it to be listed in Google's local jobs results. Please only bid if you've done this type of work in the past. You will need to add proper code markup to the site.
...with us in the future. Here are some specifics: - Generally need to ensure that the information on the "old" menus can be conveyed on the new menus - Use your discretion on design elements - Use fonts that are commonly standards or provide fonts with the project submission - The deliverables should be both a .jpg and a corresponding photoshop file -
Hi there. We need support to design a custom ARM Quad-Core Board. The Board will be small size SoM so it can be used to other Board as a Module. It will mainly consist of: - Power Management - ARM Quad-Core CPU - RAM 1GB/2GB - eMMC 8/16GB for OS Boot (Linux) For CPU we like to use either Allwinner H6 or RockChip RK3328 as we need USB 3.0. Other
I need a sudoku board in android. I don't need the whole game, only the construction of the board, and the buttons to fill it. I will supply a valid sudoku. The board should have annotations, and two ways to fill it: numbers based and cells based. It should be done in the most simple way. If done correctly, I may contact you again to help me finish
I already have the schematics. The freelancer should use Eagle CAD to finish the PCB layout according to my requirement of the dimension.
1. Name of company is - The Downtown Board [se connecter pour voir l'URL] a. Logo has to be: i. Clean ii. a Sleek look iii. brushed silver metal iiii. crisp white look This will be added to site and advertising on a site where you can find for a nice board room you can rent in the down town of your choice. Could


text:
Jonathan Vandenbroek smiles when I ask him why he chose the stage name Milow.
My real name, he says, is too Belgian – it's long, and hard to pronounce for English speakers.
"Milow" seems to be working for him, though. He's becoming known not just in Belgium, but across Europe.
He's touring relentlessly to promote his latest album, "North and South".
Milow was born in Antwerp, but grew up in a small town not far from Leuven. Belgium's small size made it easy, he says, to get to concerts – his first was Pink Floyd in 1993.
He says he loved the standard rock of the 1980s and 90s, but he found himself reaching back into the 70s.
"I never made it a secret that I love that era," Vandenbroek said. "I love the early Springsteen, Joni Mitchell, Van Morrison, Jackson Browne, so I …you know, you don't really think about it too much, you just sort of do what you feel like doing, and I started writing acoustic based music."
After high school, Milow spent a year as an exchange student in southern California.
He says for a young singer aspiring to write songs in English, it was great.
"(I) played a lot of music, played for the first time my English songs for an English-speaking audience," Vandenbroek said. "And everything I do these days is trying to you know, the symbolic moment where I play my first headlining concert in southern California. That would sort of – the circle would be complete at that point. It would be nice."
"North and South" is nod, he says, to all the non-stop touring he's been doing from Northern Europe to Southern Europe. But the album also includes a track called "The Kingdom".
Milow says it's the first political song he's ever written. Flemish politicians actually attacked Milow on Twitter when the album was released.
It's strange, Milow says, because a few years ago, it seemed like all Belgians were united in their ambivalent feelings about their country.
"These last few years, things I think are getting a little bit out of hand between the Dutch speaking north and the French speaking south," he said. "It's this mixture … even if it's strange, and even if it comes with these ambiguous feelings, that made me as a person, and as a musician. Definitely as a musician."
And for Milow's next step?
Finding a label to bring out "North and South" in Britain and the United States. He says he'd also love to hook up with a US artist, and finally get a chance to tour in America.
"The Kingdom lyrics
Where I'm from there are no mountains
And time is standing still
Where I'm from there's barely space left
Still they're running up a hill
Where I'm from they don't like changes
Even if alarm bells ring
Where I'm from they have a princess
Where I'm from they have a king
Where I'm from they don't like dreamers
They are told to shut their mouth
Where I'm from they're divided
Between the North and the South
Where I'm from it's like a long night
That never turns to day
Where I'm from the kingdom's trembling
Where I'm from they've lost the way
Sing it loud today
Sing it loud today
I'm singing it loud today
I am the one that got away
Where I'm from they just keep rooted
Heads are always hanging low
Where I'm from the Congo River
Never got nowhere to go
Where I'm from words are repeated
But they never really rhyme
Where I'm from the kingdom's trembling
Where I'm from they're losing time
Where I'm from there's a lack of heroes
Both in politics and song
Where I'm from the more they fix it
The faster everything goes wrong
Where I'm from I still remember
So I will sing it every day
That this kingdom is still my kingdom
It's encoded in my DNA


text:
VGS: '2012 may have been a weak year for gaming in some regards, the same can not be said for 2013. There are already a lot of big games to look forward to, some of them coming out as early as next month. Here are my 10 most anticipated games of this year.'
The Ni no Kuni delay has really pissed on my bonfire *grumble*.
The wait is becoming intolerable.
I played the demo and thought i wouldnt like the combat system (i hate turned based rpgs) but ended up loving it. Day one for me and cant wait to play through the story.
legend of the draggon 2 of wait i just dreamed it was coming out this year. Maybe E3 if planets align right.
I don't know if any of these are coming out in 2013, but I'm really hyped for them:
battleblock theatre
mount & blade 2
otherwise I'm also really hyped for the usual:
the last of us
sim city
new consoles


text:
GREENVILLE, Ill.-- The GC College Baseball team redeemed themselves from last night's loss to Spalding with two wins today over the Eagles; 6-3 and 18-9.
In their first game, the Panthers came away with the 6-3 win after scoring 4 runs in the bottom of the sixth. Ryan Smith tripled and Dylan Goldsmith hit a single in the second inning to put GC up 2-0. Spalding came back in the third inning to tie the game 2-2. Spalding hit a home run in the top of the sixth, but GC answered right away. Kenny Trager and Smith each hit a double and Greenville managed to score 4 runs in teh inning, to bring the gae to its final score of 6-3. Nick Bifano earned the win on the mound for GC, facing 5 batters and allowing just 1 hit. Tyler Mitchell pitched 5.1 innings for the Panthers, giving up 4 hits and 3 runs.
The second game of the day went just as well for Greenville, with the Panthers getting a huge 18-9 victory. Kenny Trager, Hunter Bryan, and Smith each hit one home-run, Mitchell Cernek recorded a triple, and Goldsmith, Dalton McFarland, Tim Osborne, and Smith each hit a double for GC. Bifano, Dylan Bone, and Scott Voyles shared the mound for Greenville, with Voyles being credited with the win.
Greenville's record is now 8-11 (5-5 SLIAC). The team will take the field again on Tuesday, April 9, with a double header against Webster.


text:
$21.00 $30.00
Tri colored funny Welsh Corgi Cardigan Dog Wall Canvas Art corgi gift Custom Pet Portrait from Photo corgi poster Historical dog costume scene - Hunting horn FINE ART CANVAS PRINT Nobility Dogs
Welsh Corgi Cardigan Dog Fine Art Canvas Print full color Limited Edition numbered ( 1 to 200) and Signed by the artist in A3+ format (40 x 30 cm or 16 x 12 inch) in canvas. Direct reproduction from original artwork. All Artworks are my own art. All of our prints are produced on state-of-the-art, professional-grade Canon printers. We use GICLEE CANVASES with ARCHIVAL PIGMENT INKS to guarantee that your prints last a lifetime without fading or loss of color. Giclee canvas prints are extremely high quality digital art prints produced with archival quality inks and artist's canvas. A giclee print on canvas is the perfect option for clients who want to have the look of an original oil in their wall.See all collections to: http://www.etsy.com/shop/NobilityDogs
You can choose in Dimensions MENU between:
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♥ We do not accept PO BOX for shipping
♥★♥★♥★ All Artworks are my own art
♥★♥★♥★ MUSEUM AND GALLERY WRAP canvases have a signature in the back and go directly from my production - Europe. Other sizes will be shipped directly to you through my supplier located in the US and U. K and no signature on the back.
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♥ View other products from your favorite dog breed: http://www.etsy.com/shop/NobilityDogs/search?search_query=Welsh+Corgi+Cardiganℴ=date_desc&view_type=gallery&ref=shop_search
♥★♥★♥★ All Artworks are my own art
♥★♥★♥★ MUSEUM AND GALLERY WRAP canvases have a signature in the back and go directly from my production - Europe. Other sizes will be shipped directly to you through my supplier located in the US and U. K and no signature on the back.
♥★♥★♥★ Limited Edition
♥★♥★♥★ Archival inks Giclee Canvas Print
♥★♥★♥★ Satisfaction Guaranteed
1-2 business days
I'll do my best to meet these shipping estimates, but can't guarantee them. Actual delivery time will depend on the shipping method you choose.
Buyers are responsible for any customs and import taxes that may apply. I'm not responsible for delays due to customs.
Just contact me within: 14 days of delivery
Ship items back to me within: 60 days of delivery
Request a cancellation within: 2 hours of purchase
But please contact me if you have any problems with your order.
Because of the nature of these items, unless they arrive damaged or defective, I can't accept returns for:
Buyers are responsible for return shipping costs. If the item is not returned in its original condition, the buyer is responsible for any loss in value.
Please contact me if you have any problems with your order.
I'm happy to work custom and personalized


text:
Speeding train mows down 37 in Bihar
At least 37 pilgrims, most of them women, were killed and 40 injured on Monday when an express train ploughed into them in Bihar's Khagaria district, triggering a protest by locals who beat up the drivers and torched some carriages. HT reports. Going off the rails, againindia Updated: Aug 20, 2013 08:13 IST
At least 37 pilgrims, most of them women, were killed and 40 injured on Monday when an express train ploughed into them in Bihar's Khagaria district, triggering a protest by locals who beat up the drivers and torched some carriages.
The death toll, said sources, could rise, as many of the grievously injured were moved to hospitals by their families with the protesters holding up ambulances, relief trains and police vehicles.
The pilgrims, who had alighted from two trains on the wrong side of the platform at the Dhamara Ghat station, 250km from Patna, were crossing the track when the Patna-bound Rajya Rani Express struck them at around 8.40am. Thirty women, four men and three children were killed on the spot.
The victims were among the devotees rushing to the nearby Katyayani temple to mark the fourth and final Monday of the holy month of Sawan.
The express was not supposed to halt at Dhamara Ghat and was given clearance to pass through, but the pilgrims on the tracks thought they could stop the train, railway board chairman Arunendra Kumar said in Delhi. Though the driver applied the emergency brakes, it was too late.
The train skidded to a stop after around 150 metres, where locals and devotees surrounded it, pulled the driver out and thrashed him, a police officer said. The driver is critical.
The mob then torched several coaches of the express train and the other two trains. They also took some officials hostage and vandalised the station.
Senior officer sent from the nearby districts to control the situation were forced back and could only reach Dhamara late afternoon. Police had to escort the two relief trains that moved the injured, many of who are critical, to hospitals.
Medical aid was also delayed as the station has no road access. "The problem is that one has to carry the injured for more than 6km on foot, as there is no road access to the station," said additional director general (law and order) SK Bhardwaj in Patna.
Forced to cancel several trains, the railways lost Rs. 25 crore in Monday's violence.
Prime Minister Manmohan Singh expressed deep sorrow over the deaths and appealed for calm, a PMO statement said.Read: For these devotees, sawan ends in a blood bath
Chief minister Nitish Kumar said the accident was 'most unfortunate'. But the BJP and Rashtriya Janata Dal criticised the delay in providing medical aid. Relief and rescue efforts could have been better coordinated, RJD chief and former CM Lalu Prasad said.
As many as 40 people are killed on tracks by speeding trains in India. Safety remains a big concern as the deaths of "other than passengers" on Indian rail tracks are many times higher than the total number of such fatalities in the rest of the world.
A map showing where the incident took place
Video: Dhamara station ransacked by mob
First Published: Aug 19, 2013 10:32 IST


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Think about what this scene would read like in a script, or even an outline:
The retarded lumpy cat follows.
He's too stupid to know the order of opening and closing a door, so he closes it first then runs into the wall instead.
The wall envelops him in rude rubbery wall skin.
Sylvester, from outside, opens the door again and motions to the other pussycats" C'mon fellas, hurry up!"
When he opens the door it slams over the retarded cat who is stuck in the wall.
The door is rubber too and forms around the lumpy dumb cat and leaves his tail balled up in a nasty place.
Sylvester slams the door open.
The other side of the door now has the dumb cat stuck to it.
The door flesh spits the retard out and he bounces onto the floor.
A small Sylvester cat runs into the scene over the retard and jumps off his butt and through the keyhole.
The hole quivers invitingly and attracts the notice of the 'tard.
The retard decides he will try jumping through the hole. He anticipates.
Out of nowhere, a baby cat runs into the scene grabs the keyhole and stretches it down to his level.
he jumps through the quivering hole.
The 'tard cat dives towards where the hole used to be and hits the door hard and falls down.
The end.
Is the scene necessary to the plot or character development of the cartoon? Does it further the arcs? Does it sound funny in words?
Why is it so great then? Let's look closely at the bits that make it up.
Design: This is a great looking shot. The perspective is exagerrated to give a sense of weirdness to the scene before anything even happens. It's not "wonky". It's planned to compose well with the characters.
Great Animation Exaggeration: The drawings in the animation are super exaggerated when you still frame them, but move smooth as silk when you watch it in real time.Accents: Clampett's accents are stronger than anyone else's in history. Accents are punctuation. They draw attention to what you want the audience to notice.
Clampett's accents are not merely functional. They are also part of the entertainment. Watch this stuff in real time and see just how much fun the movements are.
In a Freleng cartoon, the accents are just barely readable. Accents are like the rhythms in music. The punctuation in music is what gives it its excitement.
Some folks got rhythm. Others don't. Clampett gots rhythm.
This is the keyframe that "reads". The ones before and after give it the powerful accent.
"Design" in almost every frame. While there are whole articles and books about the "design elements" in the odd scene in the odd UPA cartoon and everyone gets all excited about them (including me), I'm sitting watching Clampett cartoons and finding great shapes and forms and compositions on every frame.
This wide door is a functional inbetween that just happens to also look really cool. It looks cool still and in motion. That's ultra design.
This antic pose is a beautiful design. Everything flows along the line of action and the pose composes well with the background shapes.
Weirdness is one of the most important elements of a cartoon and Clampett gives you more than anybody.
How gorgeously rude is the drawing of the cat stuck in the wall membrane?
You'd think the cat stuck in the wall skin was the end of the gag, but nope, Clampett thinks up a topper.
Now the pussy is vacuu-formed by the door and on top of that, the tail is...you know.
The animators love those muzzle-bulbs as Chloe calls them.
Ye Gods, is that a great drawing of weirdness!
This cell setup should be hanging in The Louvre. On the ceiling.
Muzzlebulbs to the extreme.
Quivering Animated Orifices:
I can't believe the love the animator put into the drawings of the quivering hole! Look how great that shape is!
Pure cartoon-design genius.
Run the clip again and watch how the hole moves. You can really feel that sucker.
Ouch. Where else would a Clampett cat step first?
Clarity/Directing Each Story Point:
Every important part of the continuity is punctuated with animation tools and accents.
When a cartoon is moving this fast and so many things are happening, clarity and punctuation is super important.
Clampett can cram more ideas and action into a few seconds than anyone. Being able to coordinate and control them so that you don't miss them takes immense skill and control.
Clampett is the ultra director. He uses his tools more than anyone, and has a larger toolbox to boot.
Part 2 tomorrow...


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WILMINGTON, Mass. — A year ago, Jared Knight showed up at Bruins development camp the week after the organization used a second-round pick to draft him weighing in at around 180 pounds.
For this week's fifth annual development camp at Ristuccia Arena, Knights' carrying around about 200 pounds, which sort of makes him look like an Incredible Hulk-like specimen — if the Hulk was just 5-foot-11.
"Hockey players, they can't be body-builders. But you want to be strong," said Knight today after the second day of development camp. "You're going against solid guys. I'm a smaller guy, so I've got to be solid. I've got to be able to take care of those guys."
Some players add bulk and struggle to get used to their new body (remember Blake Wheeler? Brandon Bochenski?). But Knight says he's had no such problem.
"Not at all. I think it's really helped me because I added a lot of lower-body strength and it's made me quicker," said Knight, who put 70 points on the score sheet last season with London (OHL). "I've got a lot faster two steps there, so it's helped me."
The bulk will help Knight do what he does best even better. He's a bit of a mucker of a power forward, even though he possess a lethal wrist shot. Even in development camp, he's shown that he's not going to just rely on his shot to score. He ran over goaltender Michael Hutchinson during on drill Thursday.
"I enjoy doing it," he said about going to the net. "Not a lot of players like doing it, and it's something I think that really sets me apart from everyone else. I get in the dirty areas, and it's fun for me. It's fun going full speed across and stirring it up."
That's the type of philosophy the Bruins like to hear from their prospects. Through two days of his second development camp, Knight has been one of the standouts. Providence (AHL) head coach Bruce Cassidy, who had Knight for three games on a tryout at the end of last season, even admitted that the real measuring stick for Knight will be when he arrives for training camp in the fall.
But that doesn't mean Knight, who would have to go back to junior in the fall if he doesn't make the NHL roster, can't throw his weight around among the prospects and try get a head start in pursuit of a pro career.


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Romney takes campaign detour to Daytona
DAYTONA BEACH, Fla. – Two days away from a critical primary in Michigan, Republican presidential candidate Mitt Romney detoured to Daytona International Speedway on Sunday.
Romney visited the track for a few hours before the scheduled start of the Daytona 500. He spoke briefly at the pre-race drivers' meeting and spent time walking around the garage and pit areas, shaking hands and taking photographs with fans.
Asked if he would be rooting for something bad to happen to the No. 26 car being sponsored by Republican rival Rick Santorum's campaign, Romney laughed, saying, "I hope all the cars have a good race."
Even Santorum's?
"I just hope they all have a good race," Romney said.
Romney was introduced at the drivers' meeting and received hearty applause from drivers, team members and other VIPs.
"This combines a couple of things I like best, cars and sports," Romney told the group. "I appreciate the spirit of the men and women that are driving today. This is a chance to really look at some of the determination and great qualities of the human spirit. This is quintessentially American. I love what you're doing, happy to be here today, wish you all the very best and God bless this great nation of ours."
He delivered similar remarks to the fans, briefly speaking on a stage in the infield during driver introductions.
Fans yelled messages of support as Romney roamed around the infield, although at least one shouted "Santorum!"
Asked if taking time to appear at Daytona was an indication of his level of confidence going into Tuesday's primary in Michigan, Romney said it wasn't.
"No, it's a sign of a guy who loves cars," Romney said. "And this has always been a place where American cars have shined. And a long history from Daytona being connected with Detroit, with Detroit cars, and with the spirit of America."
Romney was at Daytona last year and said he also has been to the track in New Hampshire. When asked how closely he follows the sport, Romney acknowledged that he isn't necessarily a hard-core fan but has a working knowledge of the sport and friendships with some of the people involved in racing.
"Not as closely as some of the most ardent fans," he said. "But I have some great friends that are NASCAR team owners."
Romney said he has visited team owner Richard Childress' facilities and came away impressed by the technology.
"I go back to the 1960s, back then when you had guys like Bobby Allison driving, they were driving stock cars," Romney said. "Maybe they'd taken out the passenger seat and the back seat so they can put in a restraint system and a fire extinguisher. But now these cars really are built from the ground up entirely by the teams themselves."
Romney spent time talking to team co-owners Chip Ganassi and Felix Sabates, who took Romney over to meet driver Jamie McMurray on pit lane.
Driver Brian Vickers walked along with Romney's entourage for most of the morning and spent time talking to Romney.
"I'm a supporter of his, and I like his policies," said Vickers, who is not in the Daytona 500 field.
With a campaign event scheduled in Michigan later Sunday, Romney wasn't scheduled to stay for the race -- just as well, because it was postponed until Monday by rain.
Earlier Sunday, Santorum discussed his campaign's sponsorship of the No. 26 team and driver Tony Raines on ABC's "This Week."
"I talked to (Raines) about a strategy," Santorum said on the show. "I recommended he stay back in the pack, you know, hang back there until the right time, and then bolt to the front when it really counts. So let's watch. I'm hoping that for the first, you know, maybe 300, 400 miles, he's sitting way, way back, letting all the other folks crash and burn, and then sneak up at the end and win this thing."


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text:
Browsing Graduate School by Author "Speckien, Mark."
Now showing items 1-1 of 1
Magnetic investigation of the continental-oceanic crustal boundary ; northern Gulf of Mexico. Speckien, Mark. (, 2012-11-29)Current mapping of magnetic intensity data shows that the Gulf Coast magnetic anomaly is not one anomaly but two distinct anomalies, with one portion trending parallel to the margin before curving northward through central ...


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CAMBRIDGE, Mass. - The Northeast Fencing Conference (NFC) recently announced its All-Conference Team with MIT's Cordelia Link and Molly Kozminsky receiving honors. Link became Tech's first four-year recipient, while Kozminsky tabbed her second nomination.
Link, a senior, became the first MIT fencer to receive four First-Team honors after the foilist posted a 28-4 record in conference competition. Kozminsky was 30-6 against NFC opponents this season and was named to the Second-Team in sabre.
Teams in the Northeast Fencing Conference include Boston College, Boston University, Brandeis University, Brown University, Dartmouth College, the University of Massachusetts, the University of New Hampshire, Smith College, Tufts University, and Wellesley College.


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Android Parental Monitoring App
Budżet ₹37500-75000 INR
Needed an app that can help parents track the social network activities and general calls etc.. of their kids for supervision. Things like messages and keystrokes etc..
16 freelancerów złożyło ofertę na kwotę ₹86239 do tego projektu
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text:
The Ferris State University men's basketball program began its
climb back to the top of the Great Lakes Intercollegiate Athletic
Conference (GLIAC) when former assistant coach Bill Sall was
appointed the program's 11th head coach prior to the 2002-03
Sall embarks on his 11th season leading the Bulldog program in 2012-13 and has won four GLIAC North Division Championships and reached the NCAA Divison II Tournament three times under his direction, including a pair of regional championship game appearances.
In 2010-11, the Bulldogs won the GLIAC North Division Championship and reached the NCAA Division II Sweet Sixteen. Sall also had the opportunity to coach the NCAA Division II National Player of the Year in Justin Keenan. FSU followed up the memorable campaign by winning a share of a second-straight GLIAC North Division crown in 2011-12.
The 2011-12 campaign represented the 10th consecutive year the Bulldogs have won 10 or more games under Sall after the program had not done so in the four years prior to his arrival. FSU has also reached the GLIAC Tournament seven of the last eight campaigns.
After leading the Bulldogs to an 11-15 overall record in his
first season (2002-03) at the helm, Sall guided Ferris to the GLIAC
North Division Regular-Season Championship in 2003-04. FSU finished
the season with a 14-14 overall record, including a first place
14-4 league mark. FSU also posted its best overall record in
2003-04 since compiling a 21-12 ledger during the 1997-98
Ferris State capped off a banner 2004-05 season under Sall's directon with a runner-up finish in the NCAA Division II Great Lakes Regional Tournament. FSU reached the regional championship game for only the third time in school history during Sall's third season at the helm. In his fourth season (2005-06), the Bulldogs returned to the NCAA-II Tournament for the second consecutive campaign.
The Bulldogs, who also won their second-straight GLIAC North Division Championship with a 13-5 league mark in 2004-05, concluded the year with a 24-7 overall record and fell one game shy of advancing to the NCAA-II Elite Eight for the second time ever. FSU's 24 victories represented the third-most wins in school history.
Sall, who served four seasons (1998-2002) as the assistant men's basketball coach at Great Lakes Intercollegiate Athletic Conference member Hillsdale (Mich.) College, was the unanimous choice of a five-member search committee.
In four seasons at Hillsdale, Sall was instrumental in leading the Chargers to a 72-41 (.637) overall record and two consecutive (2001-02) NCAA Division II Great Lakes Regional tournament appearances while being involved with the program's administrative, recruiting and on-floor coaching aspects under head coach Ed Douma. The Chargers reached the regional semifinals during the 2000-01 campaign while posting a 24-8 overall mark en route to a first-place 13-4 GLIAC South Division title.
Prior to his appointment at Hillsdale, Sall was the top assistant coach at Ferris State for three seasons (1995-98) and spent the first year (1995-96) as an assistant to head coach Tom Ludwig. During the 1995-96 campaign, he had the opportunity to serve a portion of the season as the Bulldogs' interim head coach. In his brief tenure, Ferris recorded a 5-8 start before finishing the year with a 6-20 overall record. As an assistant coach, Sall helped guide FSU to a 21-12 finish along with a GLIAC Tournament Championship title and a NCAA Division II National Tournament berth during the 1997-98 season.
A nine-year collegiate assistant coach, Sall received his coaching start under Douma at his alma mater Calvin College in Grand Rapids, Mich., from 1992-95. The Knights made two NCAA Division III National Tournament appearances, claimed the 1993-94 Michigan Intercollegiate Athletic Association (MIAA) Championship and were 37-17 (.685) overall during his two seasons as an assistant coach.
Before joining the coaching ranks, Sall was a standout player at Calvin from 1985-1990. A two-time (1989-90) MIAA Co-Most Valuable Player, Sall currently ranks as the Knights' third-leading all-time scorer with 2,063 points, which included a 70-game double-figure scoring streak. The 6-5 forward also grabbed 738 career rebounds as Calvin captured three (1986, 89-90) MIAA championships, earned four NCAA-III tournament bids and advanced to the 1990 NCAA Division III Final Four. During his collegiate career, the three-time (1987, 89-90) first-team All-MIAA honoree reached double-figure scoring in 100 of 109 outings, which presently ranks second on the all-time Calvin chart. Sall, a two-time (1989-90) second-team National Association of Basketball Coaches (NABC) Division III All-America performer, is currently listed 10th (864 points) among the MIAA's all-time scoring leaders and is seventh (.586; 341-582) on the league's career field goal percentage chart.
As a prepster, Sall attained honorable mention all-state and all-area basketball laurels at Unity Christian High School in Hudsonville, Mich. The Zeeland, Mich., native displayed his athletic versatility by winning the 1985 Michigan High School Athletic Association (MHSAA) Class B State 400-meter run title. He also competed in cross country.
A member of the National Association of Basketball Coaches, Sall is married to the former Karen Brower. The couple has a daughter, Delaney along with triplets Quinton, Lydia and Hannah. Sall graduated from Calvin in 1994 with a bachelor's degree in recreation management.


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Doctors in Southampton are set to trial a new treatment for people suffering from knee arthritis.
Have you ever thought about taking part in a Medical Trial? By registering your details with MedTrials.co.uk, we are able to send your details directly to companies who are looking for volunteers to take part in their medical research studies.
Information about you is kept on a register that CROs, Pharmaceutical companies and Clinical Investigators can access to contact you regarding individual studies.
Doctors in Southampton are set to trial a new treatment for people suffering from knee arthritis.
A new clinical trial finds that a novel drug can boost the strength of radiation therapy in the fight against cancer with 'minimal side effects.' Powered by WPeMatico
Two large new clinical trials have examined the benefits of vitamin D and fish oil supplements for staving off heart disease and cancer. Powered by WPeMatico
An existing drug that people use to treat seizures can significantly reduce symptoms of major depressive disorder in a small number of participants. Powered by WPeMatico
A new antibiotic able to kill drug-resistant bacteria proves to be safe and effective in a phase II clinical trial, offering fresh hope in a global crisis. Powered by WPeMatico
Prostate cancer is common, so findings new ways to destroy it is very important. Now, researchers believe that they may have found a new drug target. Powered by WPeMatico
A new trial confirms that a combination of immunotherapy and chemotherapy boosts survival rates for people with triple-negative breast cancer. Powered by WPeMatico


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ISSO uses an express mail service that will allow you to pay for and receive your documents through DHL or FedEx.
To request express mailing of your documents, go to the following secure website:
https://study.eshipglobal.com (works best with Internet Explorer & Mozilla Firefox browsers)
You must use the website provided above – do not go through the DHL or FedEx website directly. If you choose this option, all communication will go through the eshipglobal service, who will notify us that you are requesting your I-20 to be sent by express mail.
If you use this service, you will be required to create your own user name and password in order to create an account. To request shipment, you will need your Suffolk Student ID number, mailing address, e-mail address, phone number and credit card information. You may request shipment either to your foreign address, or to a U.S. contact address. If your I-20 will be sent to a U.S. contact address, please include the name of the person who lives at that address. Please pay close attention to the information submitted, as errors in the credit card information or submitting incorrect or incomplete address information will result in a delay in the mailing of your I-20. If you experience any difficulty in registering and processing the shipment, please use the "Help" link in the site for step by step instructions.


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Car Review
2013 Mazda CX-5: Long-Term Wrap-Up
Our long-term test with the 2013 Mazda CX-5 is over, so it's time to reflect on our time with the small crossover. And the CX-5 has given us a lot to reflect on, both positive and negative. We'll start with a few positive aspects of our daily life with the CX-5.
Power and MPGs
Most of us were pleasantly surprised by the CX-5's performance. Yes, its 155 horsepower falls short of many rivals, and yes, its 2.0-liter engine isn't a match for some 4-cylinders, let alone V6s. But the CX-5 uses its engine well. Many of us felt it rarely lacked for power -- and more importantly, we know the low power figures help it return great gas mileage. That said, drivers who do want more muscle can upgrade to Mazda's new 2.5-liter CX-5, which puts out 184 hp.
The CX-5's fuel-sipping nature was another strong suit. No, our automatic model didn't return the 35 miles per gallon that's possible on a 2-wheel drive, stick-shift CX-5. But we frequently found ourselves around 30 mpg, which is impressive for a small crossover.
We were also impressed by the CX-5's value. Ours cost just under $30,000 with shipping, a big number for a compact crossover. But a base-level CX-5 starts around $22,000, placing it among the least-expensive crossovers on the market. That means drivers can pick and choose the model that's right for them. And our $30,000 figure included some truly high-end features, such as a backup camera, heated leather seats, a navigation system, a blind-spot monitor and a remote starter.
Julie, on our Public Relations team, took the CX-5 out and was impressed with the blind-spot monitoring system. She said "The blind spot monitoring system in the CX-5 put me at ease. When a car was on either side of the vehicle, a light would illuminate on that side mirror, so I knew to not try to move over."
The rear parking camera was especially helpful. Content Producer Sadie Lake said "Most streets in New Orleans are packed with cars, and the only parking available is rather snug. Plus, almost all the parking requires you to parallel park."
Practicality was yet another area in which the CX-5 shined. Although some complained about the lack of a third row -- available on Mazda's larger CX-9 crossover -- most felt the CX-5 offered impressive room for luggage, sporting equipment and, on one trip, even large dogs.
So were there any major complaints about the CX-5? You have to really rack your brain -- and go back deep in our long-term test reports -- to find them. More than one driver grumbled about the lack of room in the back seat, including when fitting a rear-facing child seat. And we heard a few complaints about the infotainment system; namely, it includes some counterintuitive displays. And while many of us found the CX-5's powerplant adequate, a few drivers wished for more power. But the new 2.5-liter CX-5 should solve those problems.
When it comes to buying a CX-5, Site Editor Brian Moody thinks there's one option everyone should consider. He said "...if you have a very active lifestyle that keeps you outdoors or have kids that participate in lots of different sports - you're going to want the all-weather floor mats. The standard mats don't hold much in terms of mud or sand. All-weather floor mats for the Mazda CX-5 are available for an extra $100."
It's hard to say if the 2013 Mazda CX-5 has been our favorite long-termer, but it's certainly been near the top. We're definitely sad to see it leave the fleet.
What we know for sure is that the CX-5 should be considered alongside other compact SUVs like the Honda CR-V and Toyota RAV4. When push comes to shove, we think most shoppers will find it a dead tie between the RAV4 and the CX-5.
The Mazda's advantage is that it just feels sharper and is more rewarding to drive than other small SUVs.


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By Cecelia Hanley
BOSTON (RNN) – In the first major sporting event since the bombs exploded at the Boston Marathon, the Bruins hosted the Buffalo Sabres on Wednesday evening.
The NHL team honored the victims of the terrorist attack in a pregame ceremony. The crowd, many of them carrying signs of encouragement for the city, gave the teams a standing ovation.
When local celebrity Rene Rancourt began to sing the national anthem, the more than 17,000 fans joined in and their volume overtook the singer.
Rancourt stepped back from the microphone, letting the crowd sing.
Copyright 2013 Raycom News Network. All rights reserved.


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Stryker continues to grow! We add new products and new employees every day. As a result, we continue to find and implement the right technology to support our growing organization.
Recently our recruiting team moved to a new system. While we have been hard at work planning for all potential issues and are expecting a smooth transition, there maybe be some glitches along the way. It's technology after all!
Have you applied with us before? Be aware that our new system will require you to create a new login and password. And if you have applied for a role recently, there is no need to reapply. Our recruiters are working through all active candidates in our existing system. A Talent Network member? Don't worry- nothing changes there and if you haven't signed up yet, now is a great time! Being a member allows you to set up automated searches for roles so you don't miss them.
Thank you for your patience through the transition process. Your experience is important to us and this new system is going to help us make that experience even better.


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Toshiba T235-S1345 AMD Turion II Notebook Review - Entering the Nile
Entering the Nile
Earlier this year AMD released big news: 135 new design wins with major manufacturers including Acer, ASUS, Dell HP, Lenovo, Toshiba and more. These victories are a badly needed boost for AMD, which has been trailing Intel in the mobile space for years. These many of these new designs are based on a new platform AMD is calling Nile - and the Toshiba T235 is among the first Nile notebooks to hit the market.
The T235 is a harbinger - and not just for AMD. Toshiba has also been struggling somewhat as of late, at least when it comes to budget ultraportables. Toshiba's earlier ultraportable, the T135, failed to earn much critical praise. The T235 is Toshiba's chance to prove that it can compete in this market.
So, what's in this new Nile-powered ultraportable? Well, have a look for yourself:
There are several advancements here, some of which are more explicit than others. The platform has moved to support for 45nm processors. Memory support has moved from DDR2 to DDR3 and the HyperTransport link is now up to AMD's latest 3.0 standard. The graphics have made a slight technical leap forward, as well, enabling DirectX 10.1 support.
None of this is exotic, but it doesn't need to be. AMD's problem has never been that it is shamefully outclassed by Intel - but it has been behind in both performance and battery life. The Toshiba T235 is one of the first new Nile products to hit the market, providing the perfect opportunity to see how AMD – and Toshiba – has improved.
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Repeat with me for the last time: It's Friday again!
That's right, people. After several years, many months, many columns and a shitload of bullet points, the Weekly News Roundup has come to an end.
I'm gonna give you a few seconds for that to sink in.
Really? I thought you'd be more distraught. Anyway, this is it.
And no, I haven't been threatened with deportation by the Government. No, I haven't been fired from the Independent. Sometimes, however, you just feel that it's time to move on to other things and I must admit that for me the time has come.
Now, I don't want you to think I'm going away. Because I'm not. So to all the haters out there heaving a sigh of relief, thanking the Argentine gods that I wasn't going to be around anymore to challenge their ill-acquired truths safely stored inside an impermeable bubble, I'm sorry to say that you're not getting rid of me. On the contrary, my next task is to directly attack that bubble. But that's another story and you will soon understand what I mean.
Back in 2010 I began writing this column after some guy I met in a bar told me he had been living in Argentina for two years and "he didn't know or care to know who the president was". Things got even worse when I mentioned Cristina and he replied: "Dude! The president has a girl's name?!"
OK, so he wasn't the sharpest knife in the drawer. But he still got me to think that many expats living in this country (not all of them, obviously), be it due to the language barrier or just the fact that they didn't give a shit, were experiencing Argentine reality from behind a Plexiglass. They could see everything that was happening around them, but they were not able to join it.
So on a rainy Friday, more specifically on August 20th, 2010, I wrote this piece of crap.
Thirty months later, this column has become a primordial aspect of my life. It has become my signature, my voice, my shrink. But above all, it has allowed me to connect with all of you who looked for a place to engage in collective catharsis and blow off some steam. And I'm immensely thankful for your buena onda.
Yes, even you haters. Your regular hate mail has managed to make my days brighter many times, so come here you rascals and give me a hug.
And like I said before, this isn't goodbye. This is just an "I'll be back in a few weeks in a different way". Until then, you're on your own.
Scary, isn't it?
This is what you need to know:
- That thing with Iran keeps dominating the news this week (and by "thing with Iran" I mean the signing of a bilateral accord between Argentina and Iran that would create a Truth Commission in order to investigate the 1994 AMIA bombing) and people aren't happy. Specially because the Kirchnerite party, with a majority in both houses of Congress has decided to pass a bill authorizing it despite the fact that the entire Jewish community in the country is against it. The Senate passed the bill yesterday and sent it to the Lower House, where they expect it will be debated as soon as next week.
- But since we know that what we really crave as human beings are anecdotal politics, here is Kirchnerite Senate majority leader Miguel Angel Pichetto, who in the heat of the debate made a distinction between "Jewish Argentines and Argentine Argentines." Oops!
- The Jews, affable but with deadly ninja moves, were not amused by this. So now they are suing him for discrimination.
- But wait! Pichetto says he's sorry for discriminating on the Jews, specially because he's gonna get sued and all. So there, problem solved. Moral of the story: don't fuck with the Jews.
- You have probably heard about this since it has been all over the news for the last few days, but I still need to address it. First, this happened last Sunday.
- The problem with that story is that, since the person who was driving the car is the son of a prominent Government-friendly journalist named Eduardo Aliverti, the polarized media is giving us two choices of reality, and as usual we can choose the one we like more:
- Pro-Government media: Oh, that poor boy (the driver, of course). How unfair to accuse him of hitting someone with his car and not giving a shit about it. Despite being extremely drunk, he still picked up the body of the (clearly reckless) cyclist and drove him to the closest toll both where he asked for help. Verdict: Obviously innocent. It's all of us who must be blamed for living in such a judgmental society.
- Anti-Government media: The driver is clearly a monster who hit the cyclist and carried his dead body for as long as he wanted because he didn't care, because he's the son of a journalist who likes the Government so he gets special protection so nothing is going to happen to him so he deserves to rot in jail because clearly he is a serial killer. Verdict: Obviously guilty. Also, President Cristina Fernández de Kirchner should resign because somehow this is all her fault.
- Get it? Just like Lionel Hutz from The Simpsons said once: there's the truth… and the truth. Deal with it.
- Speaking of car accidents: Damn it, kids! How many times have I told you to always look both ways when you're crossing the street? If you don't learn the easy way then it's time for you to learn the hard way. Watch please.
- Oh, stop covering your eyes. No one died! In fact, they barely got hurt. Which means those two girls are either superhuman or a couple of crash test dummies that came back to life at night, like those toys in Toy Story 3 did, and got run over while they trying to get to a bar.
- Also, you gotta love the creepy bastard who spent five hours in front of his computer editing that footage, providing us with the same shocking images over and over again.
- And dude, a soundtrack? Really?
- This week, in the department of "No shit, Sherlock", Infobae tells us that when it comes to internet download speeds, Argentina is ranked number 109 in the world, between the Reunion Islands, which you didn't even know existed, and Barbados, a place you only know because an episode of Friends took place there once. Now you know why people aren't much into internet porn around here. It's not because we're puritans, but because by the time the video is done downloading, the excitement's worn off.
- A crane fell in a construction site in Puerto Madero, killing one person and injuring two others. Don't worry, nothing happened to the Faena Hotel.
- Today marks the one-year anniversary of the tragic Once train accident and society is up in arms (as it is every other day, to tell you the truth). This morning, relatives and friends of the 51 people who perished in the terrible crash attended a ceremony at the Once railway station and issued some strong statements against the National Government that included insults against Cristina, Planning Minister Julio De Vido and other Government officials, and a full rejection of the President's message last night, in which she offered her condolences to the families of the deceased. In a predictable outburst of anger, the families exorcised their demons by hurling the worst possible insults to a National Government that last year handled the death of 51 people in the worst possible way.
- Even one of the founders of the Mothers of the Plaza de Mayo organization said she disagrees with the President.
- Meanwhile, in Dubai, Diego Armando Maradona was back to his usual hijinx when he decided to appear via telephone on live television and discuss the trials and tribulations of having to deal with a new offspring with his daughter Dalma in front of 40 million people. Yeah, that's right. We jump from the somber platforms of the Once train station to the never ending stupidity of Maradona in a single bullet point. It's my last column. Let me be.
- Anyway. Dalma, who despite being like 100 million years old is behaving like a spoiled brat who is jealous of her newborn sibling, went to a TV show to cry on camera and say waaaah waaaah waaaah. Maradona, who at the time may or may have not been drunk/high, made a surprise appearance via Skype or something, and began asking everyone why his daughter had left the set even though she hand't left the set. "I'm right here!", the little Maradona spawn said like a million times to no avail.
- Then he greeted everyone again with a slurry "Good evening, everyone" and once again wondered why his daughter had left.
- "Damn it, I'm right here!" she said again. Now it was just sad.
- After a series of semi incoherent ramblings about who knows what, he finally said he was tired of the putos periodistas (faggot journalists) who are willing to do whatever is necessary to find a story. "Ricardo Fort isn't the only faggot in Argentina," he warned. Classy! Because the conversation wasn't bizarre enough, now Ricardo Fort becomes a part of the equation. So there he is, everyone. That's your role model. That's the kind of person you idolize. Feel good about yourself?
- This of course, caused some of those journalists to take offense.
Particularly tabloid and yellow press kings Jorge Rial and Luis Ventura, who replied one day later by detonating two nuclear bombs in the hearts of those who worship Maradona as the God of all things football. Ventura, clearly hurt, revealed "some information that he had allegedly kept secret until now": A) During that infamous drug bust in which he was arrested, Maradona was caught in bed with another dude. B) He likes boys who dress like girls (transvestites). C) He's a pedophile.
- You know what's worse? Football and the tabloid press are two things I despise. And yet, here we are. Ironic, isn't it?
- Well aware that I was retiring from the Weekly News Roundup business today, Cristina didn't waste any time and decided this was the perfect time to launch a new network suspiciously named DeporTV. The ceremony inaugurating the new channel, which is aimed at promoting sports (meaning football), featured all mandatory Government cliches, including:
- Football as the catalyst for human redemption: "I have heard from many neighborhood leaders how Fútbol para Todos changed lives in the neighborhoods, because the kids, and the husband too, stay at home," Cristina said. "They no longer have to go to the gas station or bar to watch but can instead watch the game all together, eating torta fritas at home." I know you can't see me right now, but you have no idea how fast my eyes are rolling.
- The dictatorship: "The event was also used to honor athletes that were forced to leave Argentina during the 1950s and forced to "disappear" during the most recent Argentine dictatorship in the 1970s." Because anything in this country that fails to explicitly and directly address the dictatorship = fascist.
- Maradona (Seriously): "Football legend Diego Maradona spoke at the presentation via videoconference from Dubai." How touching! Was that before or after he called several gay journalists "fags"? No, really. I just want to know.
- The press sucks: "We are going to have a channel that is not going to lie to us," Maradona said. Well, finally we see eye to eye on something! I mean, can you imagine if the local press had decided not to look the other way when you scored a goal using your hand, effectively winning the Mexico 86 World Cup? Remember, hmmm? Shut the fuck up and stop insulting our intelligence.
- Seriously, if this is going to be my last bullet point ever… if this is going to be the epitaph carved on the cover of a future "Weekly News Roundup Greatest Hits" then let me say it again: for once and for all, please, stop insulting our intelligence.
I love you, kids.
Have a great life, everyone!
Send Adrian your comments at firstname.lastname@example.com or follow him on Twitter at @AdrianBono


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Ah yes, who doesn't like the Under Boob? But is it better than cleavage? We'll have to start this debate like any good high school argument would, with a definition. The Urban Dictionary has this to say about "Under Boob" :
Under boob is achieved by wearing a very short halter top or cropped tank, also known as an under boob shirt, which exposes the bottom areas of a woman's breasts.
It goes on to explain what makes under boobs so great is that they "can be enjoyed in any public venue", much like cleavage. Now, many men will argue that an under boob is better than cleavage, or even a side boob. We're not ready to declare our opinion on which is the best view of a woman's breasts, as we respect the breast in all of its forms, but these photos are certain to make a compelling argument!


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TOKYO - Japan and the United States have agreed to discuss updating 15-year-old guidelines on their security alliance in view of China's growing military presence in the region, a Japanese official said.
After meeting high-level US officials, Senior Vice Defense Minister Akihisa Nagashima told Japanese media in Washington Friday (Saturday, Japan time) the two countries had "agreed to deepen Japan-US strategic consultations".
He said the two countries were oriented "in the same direction" on Tokyo's proposal to revise guidelines on Japan-US defence cooperation, which were introduced in 1997 with a focus on possible conflict on the Korean peninsula.
Nagashima was speaking after separate meetings with Deputy Defense Secretary Ashton Carter and Assistant Secretary of State for East Asian and Pacific Affairs Kurt Campbell.
The agreement comes at a time when state-operated Chinese ships have been spotted loitering in waters near Japan-controlled islands at the centre of a dispute with China and Taiwan, stoking fears of a maritime clash.
Japan's nationalisation in mid-September of some of the islands, known as Senkaku in Japanese and Diaoyu in Chinese, has stoked tensions in the East China Sea, with Japanese coastguard patrol ships chasing away Chinese flotillas.
In Washington the two sides confirmed they would discuss reviewing their defence roles in the face of China's military build-up and its naval expansion, formulating joint plans and promoting joint use of defence bases, Nagashima was quoted as saying.
He said the US had assured him that: "The Obama administration's tendency to place emphasis on Asia will accelerate in its second term."
Japan's Defense Minister Satoshi Morimoto said in Tokyo on Friday that Japan had been proposing to Washington that talks on the guidelines be launched this year.
"The present guidelines were produced when the Korean peninsula was in a tense situation," he told a news conference, recalling a crisis heightened by North Korea's nuclear arms and missile development.
"But the East Asian situation is not limited to the Korean peninsula and there is also the issue of China going to the ocean," said the former diplomat and university professor of security affairs.
"We want to start the process of reviewing the state of the Japan-US alliance once again by taking into consideration the qualitative changes in security risks," Morimoto said.
"After 15 years, there are risks concerning terrorism, outer space, cyberspace, maritime stability and territorial issues."
The recent deployment of US marine corps Osprey transport planes, perceived as unsafe by residents, has heightened anti-US military sentiment on the strategically-vital islands of Okinawa.
The problem has been compounded by the alleged rape of a local woman by two US servicemen and the claimed assault of a schoolboy by another.
Nagashima said US officials had apologised at the Washington meeting for the repeated acts of violence.


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Scholarship Opportunity Detail Page
Previous Page | New Search | Browse All
Ronald E. McNair Scholarship in Space and Optical Physics
|Scholarship Provider:
|National Society of Black Physicists
|Application Deadline:
|Dr. Ronald McNair and LTCOL Michael P. Anderson were NASA astronauts who perished in separate space shuttle accidents. Dr. McNair was lost in the Challenger accident of 1986 and Colonel Anderson was aboard the Columbia in February 2003. Both were accomplished physicists, friends and supporters of the National Society of Black Physicists, strong family men, and inspirational national treasures. These scholarships are offered in their memory and in the hopes of inspiring the next generation of space explorers.
|Scholarship Amount:
|Scholarship Website:
|School Type Requirement:
|Four Year College or Research University
|Applicant Class Requirement:
|Junior or Senior
|Minority Status Requirement:
|African American
|Awards Given:
|Length of Award:
|One Time Award
Scholarship Opportunity Contact Information
|Primary Contact:
Scholarship Committee Chair
National Society of Black Physicists
6704G Lee Highway
Arlington, VA 22205
Email: firstname.lastname@example.com
Phone: 703-536-4207
Fax: 703-536-4203


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Ducks down Stars
Anaheim, CA – Ryan Getzlaf registered a goal and two assists, as the Anaheim Ducks downed the Dallas Stars for the second time in three days with a 5-2 decision on Wednesday at Honda Center.
Teemu Selanne, Radek Dvorak, Kyle Palmieri and Andrew Cogliano each scored once for the Ducks, who defeated the Stars 4-0 on Monday in Dallas.
Viktor Fasth stopped 23-of-25 shots for Anaheim, which has won three of four overall.
Erik Cole and Lane MacDermid donated a goal apiece, while Kari Lehtonen allowed four goals on 26 shots for the Stars, who have lost three straight and sit four points back of the final playoff spot in the Western Conference.
"I thought all of the guys had a lot of energy and tried to do all of the little things right," MacDermid said. "We did that for the most part but they made some good plays."
Dvorak opened the scoring with a tip-in tally at the 11:44 mark of the first before the Ducks struck twice in a 5:05-span just past the midpoint of the second to grab a three-goal lead.
Selanne started the outburst with a power-play marker at the 11:33 mark of the middle frame before Palmieri cut in front from the low left side and stuffed a quick shot past Lehtonen to make it 3-0 with 3:22 left in the stanza.
Cole got the Stars on the board just under three minutes into the third when he one-timed a centering feed from Vernon Fiddler past Fasth, but Getzlaf answered with a backhander from the low left side at the 10:30 mark to push the margin to 4-1.
MacDermid's first career goal at the 18:36 mark gave the Stars some late life, but Cogliano found the empty net with under five seconds left to account for the final margin.
"I think scoring the first goal helped, and that power play goal really helped," Anaheim coach Bruce Boudreau said. "It deflated them a little bit, but they came out in the third and certainly put us back on our heels."
Game Notes
These two teams will meet again on Friday in Anaheim ... Anaheim converted on the only power-play opportunity of the contest ... Anaheim has won three straight in the series overall, including a 2-1 shootout win in Dallas on March 14.


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Car Review
2013 GMC Sierra HD: New Car Review
Work trucks aren't supposed to win beauty contests. They are purpose-built vehicles that tow everything from hay bales to 4-wheel ATVs without struggle or strain. The 2013 GMC Sierra HD, however, considers its crew as well as its cargo, providing an always comfortable and roomy interior. Sharing its mechanical underpinnings with the Chevrolet Silverado HD, GMC adds its own DNA, including the popular Denali trim. The result is a work truck better suited for the owner of a company than someone who works in the trenches. With 24 trim and model combinations, including three cab styles, single or dual rear wheels and gasoline or diesel engines, the GMC Sierra HD pickup covers all the bases in style.
What's New for 2013?
A bi-fuel compressed natural gas (CNG) 6.0-liter V8 engine is now available on the 2500 HD Extended Cab. Powertrain grade braking on the 6.0-liter powertrain can now operate in normal mode. Previously, engine braking was only available when tow/haul mode was engaged.
What We Like
Bold and aggressive styling; rugged interior on Work Truck trims; CNG bi-fuel capability; EZ lift/locking tailgate; best in class 18,000-lb conventional tow rating on 3500HD
What We Don't
Fifth-wheel tow rating falls short of RAM 3500HD by nearly 7,000 pounds; Denali trim available only on Crew Cab models; no manual transmission offered; side and curtain airbags not standard on all trims
How Much?
Fuel Economy
The standard engine for the 2013 GMC Sierra HD is a 6.0-liter V8 with variable valve timing. This engine produces 360 horsepower and 380 lb-ft of torque. A CNG option is available, allowing the driver to seamlessly switch between gasoline and CNG. Optional is the Duramax 6.6-liter turbodiesel that makes 397 hp and 765 lb-ft of torque. Both engines are teamed to an Allison 6-speed automatic transmission. There is no manual transmission option. The Environmental Protection Agency does not require or test HD trucks for fuel economy ratings.
Options & Standard Features
The GMC Sierra HD comes in myriad trims, body styles and configurations. 2500 and 3500 models can be had in Regular, Extended or Crew Cab, with 6.5- or 8-foot beds, single or dual rear wheels and 2- or 4-wheel drive.
The base Work Truck ($30,545) includes a minimal dash and interior better suited to dealing with dirt and grime. Standard equipment includes rubber flooring, 40/20/40 bench seat, air conditioning, tilt wheel, rear step bumper, 8-lug steel wheels and ABS.
The SLE ($34,615) trim adds power windows and locks, CD player, cruise control, upgraded interior, rear defrost, heated outside power mirrors and bucket seats with power driver's seat.
The SLT ($42,595) trim brings even more standard equipment, including heated front seats, leather seating surfaces, automatic temperature control, a trailer hitch receiver, aluminum wheels and Bluetooth.
The Denali ($47,805) adds ventilated front seats, power adjustable pedals, 12-way power adjustable front seats, power retractable side mirrors, a heated steering wheel, rear park assist, rear backup camera and a Bose premium 7-speaker audio system.
Optional equipment includes the Duramax 6.6-liter turbodiesel engine, in-bed cargo management system, Ultrasonic Rear Park Assist, a rear seat DVD entertainment system, navigation radio, Wi-Fi (dealer installed hub, requires subscription), tubular running boards, EZ-lift tailgate (SLT) and a skid resistant bed liner. Optional safety features include front side and side curtain airbags.
Mechanical options include 4-wheel drive, dual rear wheel axle, 4.10 rear axle, heavy-duty locking rear differential, heavy-duty trailer package (2.5-inch receiver and 2-in adapter, 7-wire harness and trailer brake control), snow plow prep (10-amp power source, 160-amp alternator and wiring harness for forward and roof mounted lamps and skid plates), high payload performance package, high idle switch, tri-folding hard tonneau cover and various work site and utility options.
Every GMC Sierra HD features anti-lock brakes, front airbags, StabiliTrak electronic traction and stability control, OnStar Crash Response and Crisis Assist and a tire pressure monitor. In the National Highway Traffic Safety Administration's tests of the Sierra HD, the truck performs as well as most, with an average overall score. Trucks without optional side airbags earned much lower ratings than trucks with airbags, with Crew Cab models scoring slightly better than Regular and Extended Cabs. The Sierra HD also earned scores ranging from three to four out of five stars in the roof rollover test, depending on body style and cab configuration.
Behind the Wheel
The Sierra HD is a big truck, so its ride and handling are predictable. But what we didn't expect was the extent to which the Sierra's cabin shuts out road and engine noise (especially with the Duramax diesel chugging away) and how good the feedback response is from the steering and brakes. With the diesel engine on board, the Sierra's ability to tow and haul is impressive. A conventional tow rating of 13,000 pounds for the 2500 and 18,000 pounds for the 3500 should suffice for most chores, but adding a fifth-wheel hitch allows those figures to rise to 17,800 and 23,100, respectively.
Two of the most helpful features for drivers are the powertrain grade braking system on the Allison 6-speed and the smart exhaust braking system on the diesel engine. Grade braking uses the engine's torque to help slow the vehicle when descending long grades, thus saving on brake wear. Similarly, the exhaust braking system works by restricting exhaust flow, thus producing a situation in which the compression in the engine is held steady and resulting in the engine holding or slowing power output. Both systems are invaluable when trailering heavy loads through mountain or hilly passes.
Other Cars to Consider
RAM 2500/3500 HD -- The RAM HD out-muscles and out-tows the Sierra, in some cases by as much as 7,000 pounds. The RAM's Hemi V8 offers more horsepower and torque than the Sierra, but the RAM's ride can be rough and its long-term resale figures are not as strong.
Ford F250/F350 -- Ford's heavy-duty trucks offer more horsepower and torque, more trim and cab options (such as the King Ranch and Platinum trims) and more sophisticated audio and infotainment systems (SYNC).
AutoTrader's Advice
With so many trims and configurations, it is impossible to say which model is the overall favorite. Much depends on your needs. If you're not a site manager or oil rig crew, and if you just need a big truck for towing a vacation or horse trailer, the Sierra HD Denali will most likely please you. Those looking for a workhorse should consider the 2500/3500 Work Truck, while those needing both a work station and a family hauler will likely find the 2500 SLE strikes a nice balance between features and price.