text:
|Cell Line Description:
|This human CysLT2-expressing cell line is made in the Chem-1 host, which supports high levels of recombinant CysLT2 expression on the cell surface and contains high levels of the promiscuous G protein Galpha15 to couple the receptor to the calcium signaling pathway. Thus, the cell line is an ideal tool for screening for antagonists of interactions between CysLT2 and its ligands.
|The cysteinyl leukotrienes, leukotriene C4 , leukotriene D4 and leukotriene E4 , are arachidonic acid derivatives modified by glutathione, Cys-Gly or Cys. Activated mast cells release cysteinyl leukotrienes, which cause smooth muscle contraction, airway constriction, and vascular permeability. The biological effects of the cysteinyl leukotrienes are mediated by two GPCRs, CysLT1 and CysLT2. CysLT2 is expressed in moncytes/macrophages, mast cells and eosinophils. A coding polymorphism in CysLT2 that results in a receptor with reduced response to LTD4 is associated with asthma.
|Growth Properties:
|Host Cell:
|Cell Line Validation:
|1. Gene expression: qPCR experiments determined specific silencing of CYSLTR2. 2. Protein expression: CYSLTR2 in this cell line has been validated by immunocytochemical staining.3. EC50 for calcium mobilization by leukotriene C4: ~ 19 nM.
|Calcium flux assay, ligand binding assays
|Complete growth medium: DMEM with 4.5 g/L glucose + 4mM glutamine + 10% heat-inactivated FBS + 1x Nonessential amino acids + 10mM HEPES + 1x Pen-Strep + 250μg/mL Genetecin/G-418 Plating medium: DMEM with 4.5 g/L glucose + 4mM glutamine + 10% heat-inactivated FBS + 1x NEAA + 10mM HEPES + 1x Pen-StrepAtmosphere: air, 95%; carbon dioxide (CO2), 5%Temperature: 37 °C
|Starting Cells From Frozen Cell Stock:
|1. Immediately upon receipt, thaw cells or place cells in liquid nitrogen. Maintain frozen in liquid nitrogen for up to 5 years. 2. Thaw cells rapidly by removing from liquid nitrogen and immediately immersing in a 37°C water bath. Immediately after ice has thawed, sterilize the exterior of the vial with 70% ethanol. Transfer contents of the vial to a T75 flask containing growth media. Place the flask in a humidified incubator at 37°C with 5% CO2. 3. After 8-24 h, all live cells will be attached. Viability of the cells is expected to be 50-80%. At this time, replace media to remove residual DMSO, and return to incubator.
|1. When cells are approximately 80% confluent, passage the cells as follows: Remove media and wash once with HBSS without Ca2+ and Mg2+ (10 mL/T75). Add 0.05% trypsin/0.2 g/L EDTA (1 mL/T75) and place in humidified incubator at 37°C with 5% CO2 until cells begin to round up and detach (5-10 minutes). Gently rap the side of the flask to dislodge the cells. Neutralize trypsin by addition of 4 mL Growth Media per 1 mL trypsin. 2. Cells are typically passaged 1:10 every 3-4 days. Passaging ratio may be varied according to requirements of the investigator.
|Mycoplasma Status: Negative (MycoAlert Kit)
|Freeze Medium:
|Freezing medium: DMEM with 4.5 g/L glucose + 4mM glutamine + 20% heat-inactivated FBS + 1x NEAA + 10mM HEPES + 1x Pen-Strep + 10% DMSO
|Liquid nitrogen
|1. Frozen stocks of cells should be prepared at the earliest passage possible after thawing, as follows: Count detached cells (prepared as in Subculture-Step 1). Centrifuge cells at 200 x g for 5 min. Resuspend cells at 5 x 10^6 cells/mL in Freezing Media (cell densities of 2-10 x 10^6 are also acceptable if necessary). Dispense 1 mL aliquots into cryopreservation vials. Freeze the cells by a controlled rate process, such as in an isopropanol-jacketed container placed at –70°C overnight. Store the vials in liquid nitrogen. 2. Use of cells immediately after thawing is feasible for some cell lines and is being further validated. Some cell lines may need to be passaged at least once after thawing prior to use in calcium flux assays. Cells should be resuspended in Plating Media for plating for calcium assay.
|Safety Considerations:
|The following safety precautions should be observed.1. Use pipette aids to prevent ingestion and keep aerosols down to a minimum.2. No eating, drinking or smoking while handling the stable line.3. Wash hands after handling the stable line and before leaving the lab.4. Decontaminate work surface with disinfectant or 70% ethanol before and after working with stable cells.5. All waste should be considered hazardous.6. Dispose of all liquid waste after each experiment and treat with bleach.
|Dry ice
|Gene Name:
|CYSLTR2 cysteinyl leukotriene receptor 2 [ Homo sapiens ]
|Official Symbol:
|CYSLTR2; CYSLT2; CYSLT2R; HG57; HPN321; KPG_011; hGPCR21; cysteinyl leukotriene receptor 2; PSEC0146; G protein-coupled receptor; G-protein coupled receptor GPCR21; G-protein coupled receptor HG57; cysteinyl leukotriene CysLT2 receptor
|Gene ID:
|mRNA Refseq:
|Protein Refseq:
|UniProt ID:
|Chromosome Location:
|Calcium signaling pathway; Class A/1 (Rhodopsin-like receptors); Eicosanoid ligand-binding receptors; Endothelins; GPCR downstream signaling; GPCR ligand binding; GPCRs, Class A Rhodopsin-like;
|cysteinyl leukotriene receptor activity; leukotriene receptor activity
Welcome! For price inquiries, please feel free to contact us through the form below. We will get back to you as soon as possible.


text: During Fashion Week the Lincoln Center, located between West 62nd and 65th Streets and Columbus and Amsterdam Avenues, is THE place to be! The key international designers are showing the A/W collections here and there is always a big buzz – you can see all famous faces of fashion and many celebrities rushing in and out. Today Ralph Lauren and Calvin Klein are presenting the latest in American Fashion – super exiting for Grown-Ups. But what about our little Miss Magenta – oh, she is in paradise, guess what BARBIE threw open the sparkly, pink doors of her "Dream Closet". The "Dream Closet" is a whole 9,000-square-foot event space, decked out with life-size Barbie's sporting modern day fashions that echo the doll's past. WOW!

subset: commoncrawl


text:
Canals & Trails Credit Union of Lockport, Illinois has been serving members for more than 55 years. Its type of membership is a state-chartered natural person credit union.
Checking services include no cost share drafts, share certificates with low minimum balance requirements, bill pay services and overdraft protection. Debit cards and prepaid debit cards are available.
For members needing to establish credit, the credit union offers share-secured credit cards.
In addition to vehicle and personal loans and other types of credit, Canals & Trails CU can do real estate loans. Convenience services include low-cost wire transfers and money orders. Canals & Trails CU members may also take advantage of income tax preparation assistance and tax refund loans.
Individuals with other financial, savings, and investment needs will want to consider certificates of deposits and insurance/investment products that are offered.
The "virtual branch office" can be accessed via web banking, bank by phone and smartphone. Electronically from anywhere, you can inquire into your account, order checks, loan payments, check previous transactions, make share account transfers, bill payer service, download your account history and view electronic statements.
Free credit report for Canada residents.
Monitor your credit and protect against identity theft! Who checked your credit report recently, and what did they see?
Joliet Municipal Employees Federal Credit Union , Joliet (4 miles.)
Abri Credit Union , Romeoville (4 miles.)
Romeoville Community Credit Union , Romeoville (4 miles.)
New Century Federal Credit Union , Joliet (6 miles.)
NUMARK Credit Union , Joliet (7 miles.)
Special offer to credit union members. See your instant credit report.
Also see our daily credit union news page.
Online newspapers and TV stations serving Lockport and Illinois: Chicago Tribune, USA Today, or view a national listing of newspapers.
Thinking of buying a car? See Illinois car dealers listed alphabetically by city.


text:
New Technology at the 2011 Color Management Conference
Friday, November 11, 2011
Press release from the issuing company
The 2011 Color Management Conference brings together the best practices with cutting edge technologies and solutions that offer a look into the future of color management techniques and utilities. Vendor sessions from Bodoni Systems, CHROMiX, Inc., Eizo Nanao Technologies, Fujifilm North America Corporation, GMG Americas, and Ricoh Americas Corporation will give attendees the opportunity to ask questions and learn about each vendor's products and services.
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text:
Best-selling Christian books can be purchased from local book or faith-based retailers and online book stores like Amazon, Barnes and Noble or Family Christian. Christian books can be viewed online based on their rating, price or format. Category searches under the Christian category include biographies, best-sellers, personal growth and religion.
In order to purchase Christian books, visit the website or a local book or Christian store. Christian books can be found in categories including fiction, non-fiction, religious, spiritual or self-help.
Christian books can also be searched, found and purchased based on a specific author. An author search will yield results of the specific writer's available titles. Some popular Christian authors as of 2015 include Beth Moore, Max Lucado and Sarah Young.


text:
Association Voting Procedures For Adopting Budget And Fixing Assessments
In many Associations (both condominium and non-condominium communities) there is uncertainty, and sometimes major conflict, over the proper procedure by which annual Association budgets and assessments are adopted. The following questions arise: A. Regarding The Budget (Expenses): – Do the owners have the right to vote on the budget OR can the Board of Directors …read more
An issue that frequently arises in Condominium and Single Family Residence ("SFR") planned communities is whether the rental of the units/homes can be prohibited or restricted. While there are still some unanswered questions regarding this issue in the State of Washington, the following legal principles should provide some helpful guidance: 1. In General. Any new …read more
Legal Responsibilities of Association Board Members & Their Potential Liability
Board Members of community Associations, just like corporate directors, are held to a legal standard of care in their conduct and decisions while serving on the Board. This standard of care applies in relation to the Association Members whom they represent. You will sometimes hear this standard described as a "fiduciary duty" (1). That description, …read more
Associations Should Be Incorporated
The vast majority of Associations are incorporated as nonprofit corporations. There are some Associations, however, that are not incorporated. This may be due to oversight or may be intentional in the case of some single-family residence Associations ("HOAs") and some pre-1990 condominium Associations ("COAs"). COAs formed after 1990 are required by state law to be …read more
Is There A Statute Of Limitations Applicable To Addressing Violations Of CCRs?
I have Association clients whose (usually newer) Board members have decided to enforce their CCRs to resolve longstanding violations. They have asked me whether there is a "Statute Of Limitations" that might bar covenant enforcement action after a certain number of years have passed. While there is a 6-year Statute Of Limitations from date of …read more
Wrongful Death Claims – The Loss Of A Loved One
A serious injury caused by the carelessness or recklessness of another person is a terrible thing, but the untimely death of family member or loved one at the hands of negligent stranger represents a truly horrific loss and a tragedy of the very highest order. In the aftermath of such a loss, the decedent's grieving …read more
COA Lien Foreclosure Eliminates Prior Mortgage Lien
The foreclosure of Condominium Owners Association ("COA") assessment liens can under some circumstances remove and eliminate a prior mortgage lien. In two recent Washington State Court of Appeals decisions the Court ruled that the COAs in those cases that had foreclosed their comparatively small assessment liens against a condominium unit had the effect of eliminating …read more
How To Interpret And Understand Community Covenants ("CCRs")
Association Boards (both Condominium and Single Family Residence communities) frequently struggle to understand the provisions of the CCRs that apply to their community. This particularly arises in the context of regulating questionable member activities and uses and the construction of improvements on member property. The particular CCRs provision in question was likely drafted by the …read more
Homestead Exemption & Foreclosure of Association Liens
A relatively obscure Washington statute (RCW 6.13.080) now requires Homeowner Associations ("HOAs") to mail notice to its members explaining that no "homestead exemption" will be recognized if an Association lien for unpaid assessments is foreclosed against their property. Such Homestead Exemption, which applies to the enforcement of judgments and a few other types of liens …read more
Injuries Occurring On Property Of Others – Premises Liability
A. Common Law Classifications In the State of Washington personal injury claims resulting from unsafe or defective conditions on another's premises (i.e., buildings, grounds and related facilities) always require consideration of the injured person's "status" on the other person's property. Washington, unlike most states, still relies upon traditional, common law classifications of the injured person …read more


text:
LEED Green Associate GA Exam Preparation - Green Building & Sustainable Design and Construction Techniques
This course aims to meet the continuing education needs of professionals who are involved in the process of sitting in for the exam to become LEED v4 accredited professionals or for those who need further learning on the principals of LEED design. This program will also benefit government officials, architects, engineers and general public sectors who are interested in managing a LEED Certified Project and is tailored to project managers and professionals in the capacity of owner representatives or facility managers.
Using a wide range of examples for materials, designs, and construction technologies from many case studies and site visits, this course prepares you to:
- Understand why a green transformation of our built environment should be.
- Explain the components of the LEED rating system and what is more important for our region.
- Apply core concepts and strategies to achieve success using the LEED rating system in our environment.
- Determine where different LEED rating systems can be applied and what is useful for our cultures and societies.
Daily Outlines:
Day one
- Introduction
- What is Green Building? Why is it important?
- The Goals of Green Building.
- Characteristics of Green Building.
- The Need for Green Building.
- Benefits of Green Building
- Technical terms used in green building.
- Integrated design.
- Foot print.
- Embodied Energy
- Measuring Environmental Performance
- Activity (1)
Day Two
- The six strategic Areas of Green Design in LEED
- Strategic Area 1: Sustainable sites
- Strategic Area 2: Water Conservation.
Day Three
- Strategic Area 3: Energy Efficiency.
- Strategic Area 4: Material Resources.
Day Four
- Strategic Area 5: Indoor Environmental Quality.
- Strategic Area 6: Innovation.
Day Five
- The Economics of Green Buildings and increasing the building value.
- LEED Green Associate Exam Preparation
- How to evaluate a building by LEED
- Activity (2) Evaluate your Home.
- Activity (3) Evaluate your Organization.
Week Two:
Day One
- Management Process
- Planning
- Organizing
- Leading
- Control
- Nature of Managerial Work
- Managerial Grid Styles
- Strategic Management
Day Two
- The Nature Of Leadership
- The Nature of Managerial Work
- The Nature of Supervision
- Effective Leadership
- Change Management
- Productive Performance Appraisal
- Delegation and Empowerment
- Supervision Tasks
- Conflict Management
Day Three
- Organizational Behavior
- Multi Culture
- Diversity
- Effective Communication
- Managing Teams
- Management in Decision Groups
Day Four
- Leadership and Management Styles
- Developing Leadership Skills
- Competent and Creative Managers
- Management Innovative Dimensions
- Followers Types
- Situational Leadership Theory
- Management in the 21st Century
Day Five
- Managerial Grid Styles
- Creativity
- Innovation
- Critical Thinking
- Emotional Intelligence
- The Habits of Highly Effective Leaders and Managers
- Related DVDs


text:
*** Note: This page is out of date. Please see the right sidebar for information about our new web site ***
Climate Justice London is part of a grassroots, anti-corporate, social justice movement to stop the climate change crisis.
Our group is a local participant in a network of organizations and activists who have joined together to build a North American climate justice movement, which emphasizes actions and education to mobilize for effective and just solutions to the climate crisis. (To find out more about this Climate Justice network, see the page about our goals.)
Our Tar Sands Campaign
For our main campaign, we are pressuring RBC (Canada's largest, most profitable bank, with a trillion dollars in assets) to give up its role as the main financier of Tar Sands projects. The world's dirtiest oil comes from the Alberta Tar Sands, which are aggravating climate change, while devastating Boreal forest ecosystems, and poisoning First Nations communities downstream. As part of this campaign, we're trying to get the University of Western Ontario to divest from RBC and to remove all ATMs owned by RBC from the campus. To learn more about this campaign, visit our Tar Sands Campaign page.
If you agree with what we're trying to do, please join us in taking action for climate justice!
For more information about the North American Mobilization for Climate Justice, check out the web site http://www.actforclimatejustice.org
If you'd like to contact us, our address is email@example.com
Here's a video from the Rainforest Action Network's tar sands campaign :


text:
Accommodations in Sainte-Cecile-du-Cayrou, France
Search 48 Accommodations in Sainte-Cecile-du-Cayrou
Save more with Secret Prices
Get instant savings with Secret Prices
Where to stay in Sainte-Cecile-du-Cayrou
Sainte-Cecile-du-Cayrou overviewSainte-Cecile-du-Cayrou is an inviting destination that has something for everyone. Though Sainte-Cecile-du-Cayrou might not have many well-known attractions, you don't need to venture far to visit inVINcible VIGNEron Museum and Chateau de Penne. In the surrounding area, you won't want to miss out on seeing Philadelphus Thomas Natural History Museum and Charles Portal Museum.
Where to stay in Sainte-Cecile-du-CayrouWhether traveling for business or leisure, Sainte-Cecile-du-Cayrou can accommodate all visitors. You can shop as many as 12 deals for Sainte-Cecile-du-Cayrou accommodations on Hotels.com, some with discounts of up to 10%. Our room prices start at 26 USD per night and here's a breakdown of hotels by star rating in Sainte-Cecile-du-Cayrou as well as in the surrounding area:
- • 7 4-star hotels from 81 USD per night
- • 17 3-star hotels from 54 USD per night
- • 18 2-star hotels from 44 USD per night
What to see around Sainte-Cecile-du-CayrouHere are some recommended places to see in the surrounding area:
- • inVINcible VIGNEron Museum (5.7 mi/9.2 km from the city center)
- • Chateau de Penne (6.6 mi/10.5 km from the city center)
- • Philadelphus Thomas Natural History Museum (8.4 mi/13.5 km from the city center)
- • Charles Portal Museum (8.4 mi/13.5 km from the city center)
- • Abbey of Saint-Michel Museum (8.5 mi/13.7 km from the city center)


text:
|The insecure password database file
|The secure password database file
|The current password file
|A Version 7 format password file
The historic function setpwfile(3), which allowed the specification of alternate password databases, has been deprecated and is no longer available.
These routines may fail for any of the errors specified in open(2), dbopen(3), socket(2), and connect(2), in addition to the following:
[ERANGE] The buffer specified by the buffer and bufsize arguments was insufficiently sized to store the result. The caller should retry with a larger buffer.
getlogin(2), getgrent(3), nsswitch.conf(5), passwd(5), pwd_mkdb(8), vipw(8), yp(8)
The getpwent, getpwnam, getpwnam_r, getpwuid, getpwuid_r, setpwent, and endpwent functions conform to -p1003.1-96.
The getpwent, getpwnam, getpwuid, setpwent, and endpwent functions appeared in AT&T v7 . The setpassent function appeared in BSD 4.3 Reno . The getpwent_r, getpwnam_r, and getpwuid_r functions appeared in
.Fx 5.1 .
The functions getpwent, getpwnam, and getpwuid, leave their results in an internal static object and return a pointer to that object. Subsequent calls to the same function will modify the same object.
The functions getpwent, getpwent_r, endpwent, setpassent, and setpwent are fairly useless in a networked environment and should be avoided, if possible. The getpwent and getpwent_r functions make no attempt to suppress duplicate information if multiple sources are specified in nsswitch.conf(5).
Visit the GSP FreeBSD Man Page Interface.
Output converted with manServer 1.07.


text:
Recipes and Tips
Our Products
Our Company
Talk to Us
Lasagna Florentine
9 long lasagna noodles
1 package JENNIE-O TURKEY STORE™ Lean Ground Turkey Breast
2 teaspoons bottled or fresh minced garlic
1 container (15 ounces) ricotta cheese
1 egg
1 package (10 ounces) frozen chopped spinach, thawed, well drained
1/4 to 1/2 teaspoon crushed red pepper flakes, as desired
1/8 teaspoon nutmeg
1 jar (28 ounces) spaghetti sauce
2 cups (8 ounces) shredded mozzarella or Italian blend cheese
Preheat oven to 350 degrees F. Cook the noodles according to package directions. Meanwhile, in a large skillet, cook the turkey and garlic over medium heat until the turkey is no longer pink, stirring occasionally. In a small bowl, combine the ricotta cheese, egg, spinach, pepper flakes and nutmeg: Mix well.
Spread 1/2 cup spaghetti sauce in bottom of a 13x9-inch baking dish. Layer half of noodles over sauce; spoon cheese mixture over noodles. Spoon 1 cup sauce over cheese; repeat layering with remaining noodles, cheese mixture and sauce. Cover with foil; bake 50 minutes or until bubbly. Sprinkle mozzarella cheese over lasagna; return to oven and continue baking 5 minutes or until cheese is melted. Makes 8 servings.
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text: 7: This is an aceo that I made as a Christmas gift for a few of my friends. I made aceo's similar and with the same design for all of them. The music in the back-ground is from the musical "Oliver" and the drama masks that I made were created using a piece of watercolor paper. | This aceo was created because the VAST gallery's theme of the month is "Simply Red" I created this aceo and a larger piece both in red. This aceo was made using a toothpick and paint of course. :) It is 2.5" X 3.5" and is available in my shop at www.paintingwpassion.etsy.com


text:
I was so freaking excited before arriving to a paradise called Boracay but the excitement heightened when I saw the white sand and the clear blue green water. Here I am feeling the happiest on our first day in Boracay.
We travelled a one hour flight from Manila to Caticlan airport, 5 minutes tricycle ride from Caticlan to Jetty Port, 15-20 minutes boat ride and 20-25 minutes tricycle ride to our hotel. After all that sweat and inconveniences from the journey it will be surely worth it once you set foot to the breathtaking paradise. We arrived around 2:30 in the afternoon and we were dead hungry because we did not have lunch yet. However, I can't resist to take my #ootd because of my blogger and my social responsibilities :D but really who can resist Boracay charm?!
Here is my first #ootd with a white sheer shirt and a cotton floral shorts.
Here is my first #ootd with a white sheer shirt and a cotton floral shorts.
Details :-
Top :- White sheer shirt from GMarket
Top :- Gray swimwear from H&M
Bottom :- Floral shorts from Cotton On
Accessories :- Shell necklace from Estacio Uno
Accessories :- Leopard shades from Forever 21'
Accessories :- Flower crown from Cotton On
Bag :- Shopping bag with triangle prints from H&M
Footwear :- Yellow flip flop from Rubi


text:
Two men died in the fatal road smash in Sheffield at 1am this morning, police have confirmed.
A black Vauxhall Astra and a blue Peugeot 206 were involved in the crash on Blackburn Road, Wincobank.
Police say a man inside the Astra died at the scene, as did a man inside the Peugeot.
Three other men inside the Peugeot were injured and have been taken to hospital.
A 20-year-old man has been arrested on suspicion of causing death by dangerous driving and failing to stop at the scene of a road traffic collision.
The road was closed but has now reopened.
Officers would like to speak to anyone who witnessed the incident or to anyone who saw either vehicle before the collision.
Anyone with information should contact South Yorkshire Police on 101, quoting incident number 82 of 20 December 2014.
Firefighters and police remained at the scene near The Railway Hotel at 7am this morning.
A fire service spokesman said it was a 'head on' crash.
She added: "Multiple people were trapped and at the moment we are still assisting police at the scene."
Crews from four different stations were sent to the incident.


text:
MCEER-12-0006 | 9/12/2012 | 78 pages
TOC: The table of contents is provided.
Notes: To learn more about the NEESNonstructural Project, click here.
Keywords: Nonstructural components. Concrete steel moment-resisting frames (SMRF). Bayesian framework. Seismic performance. Numerical simulations. Seismicity. Fragility functions. MATLAB.
Abstract: A method is developed for calculating the fragility of a nonstructural system supported by a structure subjected to earthquakes. The nonstructural system consists of a collection of nominally identical components. The input to these components depends on properties of the supporting structure and of site seismicity. It is assumed that (1) the seismic load can be described by 22 ground accelerations, and (2) the components of nonstructural systems have uncertain properties. A Bayesian framework is developed for fragility analysis. The document provides a manual clarifying the use of the MATLAB code for the developed Bayesian fragility computation. A two-story perimeter concrete steel moment resisting frame (SMRF) is used to illustrate the use of the code.


text:
Kevin Polley
From Wiki
Kevin Polley is the Founder and Director of Mutual Advantage LTD, established in 2005. He has been dominating markets on the web since 1996. Financial institutions and small business, alike, have turned to him to get the most from ecommerce technologies. His passion and expertise lie in the field of Semantic Markup and SEO standards. He loves research and as a Certified Advisor, has been a part of the Theme Zoom and Network Empire team for over 5 years.
Current Projects:
- Monitoring, developing and advocating the semantic web.
- Best standards and technology updates for the semantic web training system at Network Empire and Theme Zoom
- Inspiring the development of the TZ/NE Semantic Web Training Team.
- Kevin's current project is the development of the Semantic PinBoard Theme.
- UK Hosting company for The Automatic PinVid Traffic System.
- Quality control and best practices for the Network Empire and Theme Zoom Fanatical Help Desk
And many more.


text:
(Filed Under Fashion News). VF Corporation has hired David Conn as president-retail licensed brands, a new position with the company's subsidiary, VF Services, Inc. In his new position, Conn will identify new business opportunities with retailers under a licensed business model.
Conn most recently served as executive vice president of the Iconix Brand Group, "and played a key role in building Iconix into an industry leader in brand management and licensing," VF said. He has also held senior marketing positions with Columbia House and Candie's, Inc.
Prior to joining VF, Conn served as Executive Vice President of the Iconix Brand Group and played a key role in building Iconix into an industry leader in brand management and licensing. He also has held senior marketing roles with Columbia House and Candie's, Inc.
"Partnering with leading retailers is one of the cornerstones of VF's growth strategy...David brings a unique set of skills, capabilities and brand licensing experience to VF that will prove effective in leading our efforts in this new endeavor," Mike Gannaway, Vice President of VF Direct/Customer Teams, said.
VF Corporation consists of 25 lifestyle brands including Lucy Activewear. For further information, call the company's headquarters at (770) 753-5897.
Disclaimer: The views expressed in comments published on bodymagazine.us are those of the comment writers alone. They do not represent the views or opinions of Bodymagazine or its staff.
NOTE: Your Email will not be displayed.


text:
4289 332nd Ave Ne Carnation, WA 98014
Hi, Roger Steiner.
My name is
and I have a question about 4289 332nd Ave Ne Carnation
You can respond by either emailing me at
or call during
My Question Is:
Estimated Monthly Payment$5,051
- Photos
- Location
- Questions
- Share
- Mortgage Calculator
- Status: Pending
Listing courtesy of Windermere Real Estate/East
Hultquist Homes proudly presents their newest community located in the heart of Carnation, Brook Tree Estates! At 3048 sf, the Rushmore boasts 5 bds 3.5 bths. Chef's kitchen designed w/quartz counters, full height subway & mosaic tile, Bertazzoni range & rich Huntwood custom cabinets. Master on the main w/ensuite & spa feel. Easy walk to downtown Carnation & close to the Tolt River Park. Stop by and experience the Hultquist difference! Model open daily.
Interior Features Include:
Heating: Forced Air, Tankless Water Heater
Source Electric, Natural Gas
Floor Type: Ceramic Tile, Hardwood, Laminate, Vinyl, Wall to Wall Carpet
Exterior Features Include:
Acreage: 0.1700 Acres
Description Dead End Street, Paved Street, Sidewalk
View Mountain, Territorial
Square Feet 7500
Roof: Composition
Siding Modern
Parking Garage-Attached
Garage Capacity: 2
Other Features Include:
Subdivision: Carnation
Water: Public
Sewer: Sewer Connected
Cell: (206) 326-9422
Work: (206) 326-9422
Email: email@example.com
Listings provided courtesy of Northwest Multiple Listing Service (NWMLS). The three tree IDX icon refers to a listing provided by NWMLS.
Disclaimer: The information contained in this listing has not been verified by the owner of this website and should be verified by the buyer.


text:
Medical questions & health advice by board certified doctors
"What could this rash be?"
I woke up 4 days ago with a rash on my right butt cheek. It was slightly raised, red, and itched for 2 days. Its still there but does not itch anymore. The night before it appeared I fell asleep in compression shorts that I had been wearing. Could this be a fungal infection or something else?
This is a great question. It is very important that you make an appointment with your primary care doctor soon to discuss your rash and have a full history and physical. Although it is difficult to know the cause of your rash without seeing it, there are a few possibilities for what it could be. The first is, as you mentioned, a fungal infection, likely caused by yeast or tinea (ringworm) from the dampness and lack of oxygen from the compression shorts. This would be treated by an anti-fungal cream. Another possibility is that you have an abscess, or infection under the skin. This would be more likely if the area feels warm and it is painful to touch. This would be treated by antibiotics and sometimes an incision and drainage. It is also possible that you have a cyst, or collection of fluid under the skin. These can be monitored as they are benign, but they can be removed via a simple outpatient procedure if they are uncomfortable or if they get infected. Again, as there are multiple causes for rashes it is important that you seek care with your doctor to get a correct diagnosis and appropriate treatment.
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text: Neuroscience Update: Executive Functions Dyslexia DTI Neurodevelopemental Maturation underlies and Drives Behavior and Cognition Prefrontal Cortex is the Seat of Reasoning and Last Region to Reach Structural Maturity Moral Reasoning, Judgment, Impulse Control, Planning, Character and Behavior are directly related to the Biological Maturation of the Brain Adolescent Brain is not Structurally Comparable to the Competent Adult Brain Maturation of Executive Functions in Adolescence is Critical for SelfRegulation, Judgment, and Reasoning •Must be 25 years old •Must Have a Valid Credit Card What are they? How do they develop? Developmental risk factors Academic issues Social issues Role in Dyslexia Unique Set of Mental Functions Regionally specific to the Prefrontal cortex Mediated by flexible and dynamic neural networks Direct Cognitive and Emotional Functions Include Cognitive Initiation and Inhibition, Self Regulation, Problem Solving, Flexibility, Error Detection, Organization, Self Monitoring, & Motor Output Orchestrate the Domains of Thought and Action "The Conductor of the Orchestra" Forgetfulness, can't keep several things in mind Distractibility and inattention Have difficulty following instructions Disorganization Difficulty using sense of time to prepare for upcoming events and the future Cannot accurately estimate how much time it will take to finish a task Emotional reactivity Low frustration tolerance Lack of Initiation Impulsivity Decreased self awareness Diminished working memory Lack of anticipation Inflexibility Hyperfocus Temper Dyscontrol Weak self-calming skills Difficulty reading social cues Poor follow through Low tolerance for boredom Impatience Executive Function Levels of Analysis Anatomic Neurologic Neuropsychological Self Regulation Working Memory Organization and Planning Use of Self-Directed Speech, Rules, and Plans Prefrontal Cortex and Striatum Initiate, Sustain, Inhibit, Shifts Inhibition Delayed Gratification Goal Directed, Future Oriented Actions NeuroBehavioral Associates Biological Maturation and EF •Develops in Fits and Starts •Vulnerable to Early Insult and Chronic Stressors •Adolescent Brain is Structurally Closer to a Young Child's Brain than an Adult's Brain •Prefrontal Cortex or Executive Control Centers are Last to Mature Ontogeny Recapitulates Phylogeny Embryonic Development of an Organism follows the same Path as the Evolutionary History of its Species Genes – responsible for basic wiring – forming cells and general connections Environment: experience is responsible for fine-tuning, strengthens useful connections Integrated Neural Networks with Regional Specificity Early mother-infant interaction is important for the development of the orbitofrontal cortex during the first months of life. Early life stressful experiences may permanently damage the orbitofrontal cortex, predisposing the individual to later life neurobehavioral deficits Severe early stress induced by deprivation and abuse induces changes in the developing brain. Corticotrophin – releasing factor (CRF) hypersecretion throughout life is a consequence of severe abuse in childhood and may underlie the psychopathology that follows abuse Abuse leads to a state of chronic hyper-arousal and specific neurochemical changes occur in the brains of abused children. The memory loss of disassociative amnesia induced by psychological stress may be the result of the toxic action of high, prolonged levels of glucosteriods on the hippocampus Contributors to the risk for ED: Pregnancy complications Prematurity Toxin exposure (prefrontal) Drug/alcohol prenatal Low birth weight Post-natal injury ED possibly related to a birth defect due to a nutritional deficiency of Omega-3 fatty acids during pregnancy and while nursing (Ottoboni & Ottoboni, 2003.) ED/ADHD does not arise from increased sugar intake, food additives, excessive viewing of television, or poor child management by parents. UCLA study: Comparison of MRI scans of young adults, 23-30, with those of teens, 12-16: › Areas of the frontal lobe showed the largest difference between young adults and teens. › Parietal and temporal areas appeared largely mature in the teen brain. › Increased myelination in the adult frontal cortex related to the maturation of cognitive processing and other executive functions. Executive Functions Cortical Maturation The shades of blue symbolize maturing brain functions. Maturation culminates in the prefrontal cortex, the area just behind the brow. This is the seat of Executive Functions the area that controls judgment and the weighing of risks and consequences. Previously this area was thought to be mature by 18 but studies suggest this area is not fully developed until 25 or later . Patient Profile: Premature Birth Age: 16 Gender: Female Grade: 10th Presenting Problem: Grades don't reflect her ability, organizational difficulties, problems with recall and retention, slow to complete assignments, mild social skill difficulties Strengths: Caring, empathetic, artistic, well behaved Birth History: Premature birth at 32 weeks, respiratory problems requiring intubation/ventilation, episodes of apnea, Developmental History: Motor and language delays, OT/SP prior to Kindergarten, socially immature, escalating academic difficulties thru middles and high school Family History: Unremarkable The survival of very low birth weight infants has increased dramatically during the past decade Studies examining infants born at less than 32 gestational weeks yield consistent evidence of long term neurocognitive deficits impacting executive function Recent studies reveal a very high prevalence of higher-order neurodevelopmental impairment evident when such youngsters reach school age Approximately 50% of ex-preterm infants experience deficits in executive functioning and other areas cognitive development which require special academic support. Unexpectedly high risk of autism. Autism spectrum features may be an unrecognized feature of very low birth weight infants. Children born before 31 weeks gestation have a doubled risk for developing an autism spectrum disorder. Can We Teach Executive Functions? A growing body of research indicates that many children start school not ready to learn not because they do not know their letters or numbers but because they lack one critical ability: the ability to regulate their social, emotional, and cognitive behaviors. Current research shows that self-regulation – often called executive function -- has a stronger association with academic achievement than IQ or entry-level reading or math skills. Based on Russian Psychologist's Lev Vygotsky's work Teaching children to use mental tools to control cognition, emotions, and behavior. Research on Tools of the Mind (Diamond, Barnett, Thomas, & Munroe, 2007) showed that children who attended Tools classrooms had higher rates of self-regulation than closely matched pairs and that the level of self-regulation correlated with child achievement in literacy and mathematics. "Masters of Their Own Behavior" Executive Dysfunction NeuroBehavioral Associates Misunderstandings & Misassumptions Problem of the "Mind" not the "Body" Problem of "Motivation" Engenders Moralistic Judgments rather than a Readiness to Help Snap the Whip – Winslow Homer 1872 ADHD most likely polygenetic in nature. May involve genes governing DA and NE systems. "The 7-repeat allele:" associated with novelty seeking (more impulsive, excitable, and exploratory). – Steven Pliszka, MD. ADHD children show 3-4 percent smaller brain volumes - NIMH, 2008 2007 NIMH Study: Compared brain scans of 446 children with and without ADHD. Brains of children with ADHD develop normally but lagging behind approximately 3 years. Biological differences most evident in the frontal lobes, temporal grey matter, CN, and cerebellum. Shaw et al., 2007 Structural Differences in Brain Volume •Children with ADHD had significantly smaller brain volumes (3%) • Unmedicated youngsters with ADHD had strikingly smaller volumes (5.8%) than controls •Children with ADHD had developmental trajectories that paralleled controls but on a lower trajectory Castellanos, F. (2002) JAMA NeuroBehavioral Associates Abnormal Brain Anatomy Found With ADHD : Diffusion tensor imaging shows abnormalities in pathways between the frontal lobe, cerebellum. Kate Johnson March 2005 Children with and without ADHD "Abnormalities in fiber pathways in the frontal cortex, basal ganglia, brain stem, and cerebellum in the ADHD patients" "The circuit that connects the frontal lobe and cerebellum is not efficient in ADHD" "Fiber pathways abnormalities are less pronounced in children who have been treated with stimulant medication, compared with those who have not." "Our hope is, in the future, to be able to diagnose ADHD with this technique." Manzar Ashtari, Ph.D. North Shore-Long Island Jewish Health System Abnormal Brain Anatomy Found With ADHD : Diffusion tensor imaging shows abnormalities in pathways between the frontal lobe, cerebellum. Kate Johnson March 2005 Social Considerations Executive Functions & Adolescents Driven by Rapid Development in Prefrontal Cortex Executive Functions Self-Control Inhibition Flexibility Initiation Planning Organize Reasoning Judgment Self-Monitor Delay Gratification Assess Consequences Perspective-Taking Driving accidents leading cause of death in teenagers. Teens with ADHD two to four times more traffic accidents. Collisions 4 times more likely to occur at night. Compared Teens on Concerta, Adderall & Placebo Stimulants improved Driving Performance Concerta was more effective late in the evening when most adolescent accidents occur. 2005 Pediatric Academic Societies by Daniel Cox, Ph.D 44 teen brains examined via fMRI after teens played violent video game Less activation of prefrontal portions of the brain. More activity in the amygdala. Lingering effects of heightend emotional arousal and suppressed self-control and concentration remained. Emotional Difficulties Aggression Mood Swings Depression & Anxiety Compulsive Behaviors Alcohol and Drug Abuse Preoccupation with Appearance Self Mutilation Risk Taking Behavior Alcohol and Drug Abuse Unprotected Sex Inattention Distractibility Poor Academic Performance Planning Difficulties Test-Taking Difficulties "Maturity is not simply a matter of slipping software (learning) into existing equipment. Instead, the hardware changes. Those changes partly reflect signals from the world outside, and seem to be a peculiarly human adaptation. Think of it as nature's way of giving us a second chance." Giedd, 2002 The Brain and Reading Left Temporal Anatomy Alexia without Agraphia M. Jules Dejerine French Neurologist "Word-Blindness" One of the first reports in the literature Basis for disconnection syndromes Memoires de la Societe De Bologie, 1891 Dejerine's Patient 51 year old store keeper Left Cerebral Vascular Accident Following CVA › › › › › › Could not read words Color naming deficit R homonymous hemianopsia He could write, but not read what he wrote He could identify letters He could only identify words spelled aurally or tacitly "Linguistic Blindfold" Samuel T. Orton, M.D. - 1928 Neurologist Wife was a Reading Teacher Soft Neurologic signs Explanation of "Word Blindness" Problems with laterality Twisted Symbols & Mirror-Writing were common in poor reading "Strephosymbolia" Brain Morphology Geschwind & Fuscillo 1966 Described patient with Alexia without Agraphia Color naming deficit – color perception was intact but couldn't match color names with seen colors Color naming used as a marker for visual-verbal disconnection Led Denckla (1972) to search for children with reading difficulties who might be unable to name colors Found children with reading problems hid long latencies or hesitancies… "Lack of Automaticity" Brain Morphology Galaburda & Kemper - Cellular Abnormalities: › Clusters of Ectopic neurons in outside layer of the › › › › cerebral neocortex Ectopias are cellular migration between different cortical layers Ectopias prevalent in frontal and perisylvan language regions of left hemisphere Ectopias are produced before 6 months of gestation Found polymicrogyria – multiple narrow, short, curved gyri The Neocortex and Cortical Migration The cerebral cortex is a thin layer of cells about 1.5 to 4 mm thick. The cortex provides the connections and pathways for the highest cognitive functions, such as language and abstract thinking. The cerebral cortex contains about 25 billion neurons, more than 62,000 miles of axons, and 300,000,000,000,000 synapses. Neocortex layer The thin layer of the neocortex is dense with neurons. Brain Morphology Galaburda & Kemper 1979: › Post-mortem structure of severely dyslexic individuals › Brains were structurally different › Planum Temporale were symmetrical › Found cellular abnormalities Archives of Neurology, 1978 Archives of Neurology, 1979 Brain Morphology Beaton, 1997: "It is uncritically accepted... that Dyslexia is associated with a pattern of planum asymmetry more often reversed in direction or reduced in size among Dyslexic's." Brain and Language, 1997 Morphology of Temporal Lobe Functional Neuroimaging Shaywitz et al. - PET Study: … brain activation patterns provide evidence of an imperfectly functioning system for segmenting words into their phonological constituents. … pattern of underactivation in left posterior brain regions contrasted with relative overactivation in anterior regions may provide a neural signature for the phonological difficulties characterizing dyslexia. Dyslexia Anatomic Levels of Analysis Neurologic Functional Decoding Difficulties Phonemic Awareness §Left Superior Temporal Gyrus §Heschel's Gyrus §Broca's Area Phonological Processing Rapid Naming Spelling Difficulties Weak Writing Skills Diminished Verbal Fluency Diminished Reading Fluency Mispronunciations NeuroBehavioral Associates Fluency Denckla & Rudel, 1972, 1974, 1976 Rapid Automatized Naming Test – RAN Traced to Geschwind's description of Dejerine's: "Alexia without Agraphia" "Lack of Automaticity" Strong prediction of reading success Taxes executive control of language system Reid Lyon recommended as Kindergarten screening tool Annals of Dyslexia, 1999 Fluency RAN represents separate function from phonological processing Unique contribution to reading beyond phonological awareness Poor readers can be subtyped Phonological Deficit only RAN Deficits only Phonological & RAN Deficits Double – Deficit Model Bowers & Wolf, 1993 Fluency RAN discriminates between good and poor readers with ADHD Deficits in letter word fluency and RAN characterized ADHD – RD children LWF is executive task requires a rulegoverned, self-monitored search of the lexicon Zone of convergence linking ADHD to RD concerns the executive aspects of languageOverlap Zone Learning Disabilities Attention Deficit/ Hyperactivity Disorder Dyslexia and Adults Dyslexia and Adults DTI is a MRI technique that allows visualization and characterization of the brain's white matter tracts. DTI measures the diffusion of water molecules in brain tissue Diffusion is isotropic (equal in all directions) in CSF and cell bodies but anisotropic (greater in one direction than another) in axons that comprise white matter White matter tracts are myelinated neuronal fiber tracts that connect one brain region with another Myelin prevents the diffusion of water through the walls of the axon DTI can measure the orientation and direction of white matter tracts DTI allows assessment of the coherence or strength of white matter tracts DTI provides a quantitative index of the organization of large white matter tracts connecting brain regions Diffusion Tensor Imaging The goal of diffusion tensor imaging is to image the microstructure of the brain's white matter tracts Red is left to right Green is front to back Blue is top to bottom Water inside the white matter tracks can only diffuse in the same direction as the actual white matter fibers. In gray matter water diffuses in many directions, having ellipsoids that are more ball shaped. Water in white matter will have ellipsoids as in the picture above. These tensors can mathematically be combined to do fiber tracking, also called tractography. Fractional Anisotropy Fractional anisotropy (FA) is a scalar value between zero and one that describes the degree of anisotropy of a diffusion process. A value of zero means that diffusion is isotropic, i.e. it is unrestricted (or equally restricted) in all directions. A value of one means that diffusion occurs only along one axis and is fully restricted along all other directions. FA is a measure often used in diffusion imaging where it is thought to reflect fiber density, axonal diameter, and myelination in white matter. Isotropic Diffusion Anisotropic Diffusion Diffusion Tensor Imaging There is a rapidly expanding body of literature addressing the capability of diffusion-tensor imaging to depict normal white matter and subtle age- and pediatric disease state–related perturbations in white matter that are not visible at routine MR imaging . FA and ADC are two of the most widely used diffusion-tensor indices. FA is considered a marker of axonal integrity: White matter maturational changes are expressed in part as increases in FA Diffusion Tensor Imaging ADVANCES IN KNOWLEDGE •Diffusion-tensor imaging reveals differences in white matter structure between dyslexic and age-matched normal-reading children. •Age-related maturational changes in white matter depicted at diffusion-tensor imaging in dyslexic children differ from these changes in normal-reading children. Microstructure of Temporo-Parietal White Matter as a Basis for Reading Ability: Evidence from Diffusion Tensor Magnetic Resonance Imaging Torkel Klingberg, Maj Hedehus, Elise Temple, Talya Salz, John D.E Gabrieli, Michael E Moseley, Russell A Poldrack Department of Psychology, Stanford University, California 94305, USA Neuron, Vol. 25, 493-500, February, 2000 Compared Adults with and without Dyslexia White matter diffusion anisotropy in the temporo-parietal region of the left hemisphere was significantly correlated with reading scores within both the reading impaired and control groups Greater anisotropy may reflect greater communication between cortical area involved in visual. auditory, and language processing Neural Changes following Remediation in Adult Developmental Dyslexia Guinevere F. Eden, Karen M. Jones,Katherine Cappell, Lynn Gareau, Frank B. Wood, Thomas A. Zeffiro, Nicole A.E. Dietz, John A. Agnew, and D. Lynn Flowers Neuron, Vol. 44, 411-422, October 28, 2004 Examined adults with and without dyslexia Utilized fMRI Behavioral changes in adults receiving reading intervention correlated with: -- increased activity in the left hemisphere regions engaged by normal readers --compensatory activity in the right perisylvan cortex. Behavioral plasticity involves two distinct neural mechanisms Children's Reading Performance is Correlated with White Matter Structure Measured by Diffusion Tensor Imaging Gayle K. Deutsch, Robert F. Dougherty, Roland Bammer, Wai Ting Siok, John D.E. Gabrieli, Brian Wandell Cortex, Vol. 4, 354-363, 2005 Examined children with a wide range of reading performance levels Utilized DTI White matter structure as measured by FA and CI significantly correlated with behavioral measures or reading, spelling, and rapid naming Lower FA, reflecting diminished white matter organization, was associated with lower performance scores Findings support importance of the left temporo-parietal neural pathways in the development of reading skills Functional and Morphometric Brain Dissociation between Dyslexia and Reading Ability Fumiko Hoeft,*†‡ Ann Meyler,§ Arvel Hernandez,* Connie Juel,¶ Heather Taylor-Hill,* Jennifer L. Martindale,* Glenn McMillon,* Galena Kolchugina,* Jessica M. Black,*¶ Afrooz Faizi,* Gayle K. Deutsch,* Wai Ting Siok,*‖ Allan L. Reiss,† Susan Whitfield-Gabrieli,*** and John D. E. Gabrieli Examined adolescents with and without dyslexia Utilized fMRI techniques Found patterns of both hypoactivation and hyperactivation Hypoactivation reflected functional atypicalities related to dyslexia itself Hyperactivation reflected processes related to current reading levels independent of dyslexia Hypoactivation is related to the cause of dyslexia Hyperactivation is associated with the consequence of dyslexia-compensatory mechanisms? Prediction of Children's Reading Skills using Behavioral, Functional, and Structural Neuroimaging Measures Fumiko Hoeft, Takefumi Ueno, Allan L. Reiss, Ann Meyler, Susan Whitfield-Gabrieli, Gary H. Glover, Timothy A. Keller, Nobuhisa Kobayashi, Paul Mazaika, Booil Jo, Marcel Adam Just, John D.E. Gabrieli Behavioral Neuroscience, Vol 121(3), 602-613, Jun 2007 Examined children of varying reading abilities at both the beginning and end of the school year Utilized fMRI while performing a phonemic awareness task, behavioral measures, and structural brain measures Specific patterns of brain activation during phonological processing and white matter densities predicted decoding skills at the end of the year Combined behavioral and brain imaging techniques predicted outcome better than either alone Neuroimaging may be useful in identifying those children at risk for poor decoding and reading skills Tract-based spatial statistics of diffusion tensor imaging in adults with dyslexia. Richards T, Stevenson J, Crouch J, Johnson LC, Maravilla K, Stock P, Abbott R, Berninger V. Department of Radiology, University of Washington, Seattle, WA 98195, USA. Am J of Neuroradiology 2008 June; 29(6) : 1134-1139 Compared 7 normal adult readers with 14 adults with dyslexia Utilized DTI Higher FA values in adult normal readers versus adults with dyslexia Stronger functional connectivity in the bilateral inferior frontal gyrus of adult normal readers Expands past studies demonstrating left temporal-parietal differences Supports disconnections in structural, as well as functional, connectivity in the development of dyslexia Simple Developmental Dyslexia in Children: Alterations in Diffusion-Tensor Metrics of White Matter Tracts at 3 T1 Radiology. 2009 Jun;251(3):882-91. Epub 2009 Apr 3 CONCLUSION: Findings at 3.0-T DT imaging suggest that white matter differences in dyslexic children are not limited to the portion of the brain traditionally considered to be integral to word recognition and processing. 1.Nancy K. Rollins, MD, 2.Behroze Vachha, MD, PhD, 3.Priya Srinivasan, MS, 4.Jonathon Chia, MS, 5.Joyce Pickering, PhD, 6.Carrol W. Hughes, PhD and 7.Barjor Gimi, PhD A dual DTI approach to analyzing white matter in children with dyslexia Psychiatry Res. 2009 Jun 30;172(3):215-9. Epub 2009 Apr 5 John C. Carter,a Diane C. Lanham,b Laurie E. Cutting,bcd Amy M. Clements-Stephens,b Xuejing Chen,a Muhamed Hadzipasic,a Joon Kim,a Martha B. Denckla,bcef and Walter E. Kaufmann Used voxel-based (VBA) and region-of-interest (ROI) diffusion tensor imaging (DTI) analyses, Examined white matter (WM) organization in 7 children with dyslexia and 6 agematched controls. Both methods demonstrated reduced fractional anisotropy (FA) in the left superior longitudinal fasciculus (SLF) and abnormal orientation in the right SLF in dyslexics. Application of this complementary dual DTI approach to dyslexia, which included novel analyses of fiber orientation, demonstrates its usefulness for analyzing mild and complex WM abnormalities. Children with Dyslexia Lack Multiple Specializations Along the Visual Word-Form (VWF) System Sanne van der Mark, Kerstin Bucher, Urs Maurer, Enrico Schulz, Silvia Brem, Jsabelle Buckelmüller, Martin Kronbichler, Thomas Loenneker, Peter Klaver, Ernst Martin, Daniel Brandeis Neuroimage, vol. 47(4), 1940-9. Oct 2009 Examined children with and without dyslexia Utilized fMRI to examine activation of the left inferior occipito-temporal cortex (VWF area) Presented real word, pseudowords, and false fonts Children with dyslexia showed impaired specialization for both print and orthography Brain connectivity in non-reading impaired children and children diagnosed with developmental dyslexia. Odegard TN, Farris EA, Ring J, McColl R, Black J. University of Texas Arlington, Arlington, TX 76019-0528, United States. [email protected] Neuropsychologia, 2009 Diffusion Tensor Imaging (DTI) was used to investigate the relationship between white matter and reading abilities in reading impaired and non-reading impaired children. Seventeen children (7 non-reading impaired, 10 reading impaired) participated in this study. The data replicated previous results seen across multiple studies and extended findings to include measures of both real word and pseudoword decoding. Negative correlations were observed in the left posterior corpus callosum between fractional anisotropy (FA) values and both measures of decoding. Positive correlations between FA values and real word and pseudoword decoding were observed in the left superior corona radiata. This extension of findings regarding correlations between the corona radiata and reading skills suggests an important direction for future research into the neurological substrates of reading. White Matter Microstructural Differences Linked to Left Perisylvian Language Network in Children with Dyslexia Sheryl L, Rimrodt, Daniel J. Peterson, Martha B. Denckla, Walter E. Kaufmann, Laurie E. Cutting Department of Developmental Cognitive Neurology, Kennedy Krieger Institute, 707 N Broadway, Baltimore, MD 21205, USA Cortex, vol. 46(6):739-49, June 2010 Examined children with and without dyslexia Utilized DTI to examine white matter structure FA decreases in dyslxia in LIFG and left temporo-parietal white matter Positive corelation of FA to reading speed in a left posterior cicuit Found differences in fiber orientation in Left anterior perisylvan language pathway Links an atypical white matter structure in dyslexia to atypical fiber orientation in reading circuits of the left perisylvan language network "To find a convergence of MRI evidence… linked to an identifiable structure …Brings us closer to understanding how dyslexia happens" Altering cortical connectivity: remediation-induced changes in the white matter of poor readers. Keller TA, Just MA. Center for Cognitive Brain Imaging, Department of Psychology, Carnegie Mellon University, Pittsburgh, PA 15213, USA. [email protected] Examined whether 100 hr of intensive remedial instruction affected the white matter of 8- to 10-year-old poor readers utilizing DTI. Prior to instruction, poor readers had significantly lower FA than good readers in a region of the left anterior cerebral white matter The instruction resulted in a change in white matter (significantly increased FA), and in the very same region. The FA increase was correlated with improvement in phonological decoding ability, clarifying the cognitive locus of the effect. The results demonstrate the capability of a behavioral intervention to bring about a positive change in cortico-cortical white matter tracts. PMID: 20005820 [PubMed - indexed for MEDLINE]PMCID: PMC2796260 [Available on 2010/12/10] Neural Systems Predicting Long-Term Outcome in Dyslexia Fumiko Hoeft, Bruce D. McCandliss, Jessica M. Black, Alexander Gantman, Nahal Zakerani, Charles Hulme, Heikki Lyytinen, Susan Whitfield-Gabrieli, Gary H. Glover, Allan L. Reiss, John D. E. Gabrieli J. Neurosci. Vol. 31 (26) 9641-9648, 2011 Examined children with and without dyslexia over a 2.5 year period to determine if brain imaging (fMRI & DTI) can predict future long term gains in dyslexia Greater right prefrontal activation during a reading task that demanded phonological awareness and right superior longitudinal fasciculus white matter organization significantly predicted future reading gains in dyslexia This method predicted significantly above chance (72% accuracy) which child would or would not improve reading skills in dyslexia. Behavioral measures (testing) were at chance Right prefrontal mechanisms may be critical for reading improvement in dyslexia, perhaps identifying structures necessary for compensation What do we know… What do we think we know… Dyslexia and ADHD involve both structural and functional connectivity abnormalities and regional specificity Connectivity abnormalities are developmental rather than acquired or the consequence of reduced reading practice Left temporo-parietal hypoactivation and reduced connectivity is related to etiology of dyslexia White matter organization is weaker in left posterior brain regions Right prefrontal activation during reading and right superior longitudinal fasciculus white matter organization predicted future reading gains in dyslexics-Neuroprognosis What do we know… What do we think we know… Greater than normal white matter connectivity in the corpus callosum which may reflect an atypical reliance on right hemishphere regiions for reading Greater preintervntion activation in the right IFG and greater white matter intergrity in the right SLF, on rhyme task, predicts greaterimprovement in reading over the next 2.5 years-Neuroprognosis DTI may be helpful in measuring response to reading intervention Remediation is associated with increased activation and connectivity in left tempopro-partietal and frontal regions What do we know… What do we think we know… Psychometric testing predicted gains in decoding, accounting for 65% of variance Fuunctional and structural imaging predicted gains in decoding accounting for 57% of variance Combined behavioral testing and brain imaging accounted for 81% of variance-Neuroprognosis Event-Related Potentials (ERP's) may predict fuure language and reading problems in infants and children before reading instruction ERP response to language sounds within 36 hours of birth predict children who will go on to become dyslexic by age 8 with 81% accuracy-Neuroprognosis "The New Revolution" Educational Neuroscience- Mind Brain and Education Neuroprognosis Laura-Ann Petitto Kurt Fischer Combination of Brain Imaging and Behavioral Measures for Diagnosis Better Prediction of At Risk Children Predict capacity for Response to Intervention Possibility of Prevention Measure the Response to Intervention Shape Educational Policy and Practice Shape Health Care Policy-Insurance Guide Family Decision-Making The Frontal Lobes : The Seat of Civilization "An Interpretation of Michelangelo's Creation of Adam" JAMA 1990 The Creation of Adam (1508-1512) ceiling of the Sistine Chapel ... Meshberger, M.D. described an anatomically accurate image of the human brain portrayed behind God. On close examination, borders in the painting correlate with sulci in the inner and outer surface of the brain, the brain stem, the basilar artery, the pituitary gland and the optic chiasm. God's hand does not touch Adam, yet Adam is already alive as if the spark of life is being transmitted across a synaptic cleft.* Below the right arm of God is a sad angel in an area of the brain that is activated on PET scans when someone experiences a sad thought. God is superimposed over the limbic system, the emotional center of the brain and possibly the anatomical counterpart of the human soul. God's right arm extends to the prefrontal cortex, the most creative and most uniquely human region of the brain. *Frank Lynn Meshberger, M.D., JAMA #14 October 1990 NeuroBehavioral Associates


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- Spurs-Lakers Game Info Page | Media notes (PDF): Spurs | Lakers
This game is all about jockeying for playoff position. In the homestretch, the Spurs have two goals: To stay healthy and to catch Oklahoma City and gain home court advantage throughout the Western Conference post-season tournament.
The Lakers are intent on keeping the Clippers in the rear-view mirror by securing the third seed. And in doing so, the Lakers would face Dallas in the first round, a team they've swept in the regular season (4-0). Also, with Kobe Bryant's injured shin most likely to keep him on the bench, the Lakers have another chance to develop the offensive chops of his teammates — something that would undoubtedly make L.A. even tougher to beat in the playoffs.
- As he approaches his 36th birthday, Tim Duncan is not the player he used to be. These days, he rarely assumes the proper position in the low-post and instead mostly sets up a few steps above the foul line. From there he looks to drive, pass, screen, or shoot — all of which he does with his accustomed brilliance. Whoever will be assigned the task of guarding TD — mostly either Pau Gasol or Andrew Bynum— will therefore be forced to play defense a long way from their common comfort zone. If Duncan can routinely knock down his mid-range shots, then the Lakers defense will be stretched to the breaking point.
- Even in his prime, Duncan was never a top-notch man-to-man defender with his defensive effectiveness depending more on the help he brought from the weak-side. That's why, if left to his own devices, Duncan could easily be overwhelmed by Bynum. Fortunately for San Antonio, Bynum doesn't react well to double-teams — frequently forcing shots and/or committing turnovers. Another option is for Tiago Splitter to play Bynum straight up and use all of his fouls.
- Tony Parker may have lost a half-step but is still unstoppable in a broken field, and can finish in rush-hour traffic as well as any point guard in the league. He can be expected to run rings around Ramon Sessions, but will need to bury his jumpers when defended by the long arms and quick feet of Steve Blake.
- DeJuan Blair has to overpower and outrun Gasol. When Gasol ventures into the pivot (something that Mike Brown's game plan seldom features), Blair must get under his center-of-gravity, push him off his favorite spots, and make Gasol shoot turnaround jumpers. When his opposite number is stationed at the high-post (having much the same responsibilities there as Duncan), Blair can play Gasol chest-to-chest. In any event, this will be a key matchup.
- Kawhi Leonard has been starting as of late, and the 6-foot-7 rookie is multi-talented, but is still mostly a stranger in paradise. He certainly has the length, the skills, and the size to at least occasionally annoy Kobe some day but not today. In any event, Leonard won't get much daylight, yet when he is on the court he will inevitably be bullied by Metta World Peace, but certainly won't be outhustled by Matt Barnes.
- Look for Danny Green to start at another wing position, and likewise be subject to a quick hook. Like Leonard, Green must take advantage of his limited playing time by hitting his treys, taking care of the ball and playing alert defense.
- Manu Ginobil is San Antonio's most important bench player. Like Parker, he has lost a half-step (mostly because of injuries), yet Ginobili's left-handed slants, full-speed-ahead hustle and long-distance drilling make him a terrific clutch player and one of the most underrated guys in the NBA. If his jumper is falling, then Ginobili can withstand the rugged defense of either Barnes or World Peace.
- Gary Neal splits his minutes at both backcourt slots. He's a dead-eye 3-point shooter who's still learning how to run a team when he plays the point.
- Stephen Jackson is a hot-and-cold shooter, who always looks to shoot as though his right hand is on fire. He'll have to bring his A-game and avoid turnovers. Indeed, on his second go-round with the Spurs, SJax is averaging more turnovers than assists. Whomever he happens to be guarding, Jackson must concentrate especially hard when playing off the ball.
- Matt Bonner's job is to rebound, set sturdy screens and, above all, bury triples. Since neither Gasol nor Bynum will extend their defense to the vicinity of the 3-point arc, Bonner should have several uncontested shots from out there.
- Putting points on the scoreboard is what the Spurs do best — their 101.8 ppg ranks third in the league. In so doing, San Antonio makes 38.7 percent of their 3-pointers, second-best in the NBA. Accordingly, their long-distance dialing must connect at their usual pace.
For sure, the team-wide fire-power is there and is enhanced by their discipline and unselfishness. But the Spurs' middling defense could easily be trumped by the size and length of the Lakers' bigs. That's why they must control the defensive glass and limit the number of putbacks by Bynum, Gasol and company.
- Even if Kobe makes a miraculous (and unanticipated) reappearance, he's bound to be rusty and incapable of being the point-making genius we've all witnessed for many years. In his absence, the Lakers' offense will be much more democratic and previously non-featured scorers like Gasol, Sessions, World Peace and even Blake must all tally double-digits.
- Even so, Bynum will be the focus of the offense and must deliver. The big guy's footwork has improved greatly, which has made his pivot moves much more unpredictable. Still, when (not if) the double-teams come, Bynum has to make quicker decisions than is his wont and avoid forcing both his dribble and his shots through heavy congestion.
- On defense, Bynum has to properly read developing situations on a consistent basis in order to turn lane-penetrations (especially on the part of Parker) from layups into kick-out passes. Also, Bynum has to offer active help on every screen-and-roll, not merely when the spirit (or Mike Brown's chastisements) move him. And he must keep Duncan away from the rim by depending on his long arms to enable him to play a step soft when Duncan's at the high post while still being able to harass any forthcoming jump shots.
- Perhaps Brown will send Gasol into the low post to operate against the undersized Blair and/or the defensively-challenged Bonner. If Brown's game plan remains unchanged, Gasol must nail his mid-range jumpers and make appropriate passes from the high post.
- World Peace has a license to shoot with Kobe down and out, and he's taking full advantage of every opportunity. Indeed, World Peace is playing with more force and better judgment than he has since he came to L.A. — plus, his 3-pointers are falling. If he's lost some of his lateral defensive range, his hands and his anticipation remain superb. Don't be surprised to see him variously defending Duncan, Ginobili, or (if he gets hot) Jackson.
- Sessions likes to zip to the rim going right and pull up for accurate floaters going left. Moreover, his 3-point shooting has undergone an astounding sea change since joining the Lakers. That said, Sessions has judiciously picked his spots to shoot, while still pushing the pace at every opportunity. His only failing is inadequately dealing with high screens on defense. This necessitates substantial help from his bigs. Sessions is also susceptible to being beaten off the dribble by fleet-footed guards — not a promising sign for controlling Parker. Again, timely interior rotations by the Lakers' frontcourt is vital.
- Devin Ebanks usually starts (and quickly sits) in hopes of grabbing a few long-armed rebounds and bagging at least one baseline jumper.
- Barnes will play 30-plus minutes at both wing positions. He'll run with the guards, hit a three or two, never stop busting his butt and play clawing defense. Depending on the matchups, he must partially neutralize Ginobili, lock up Jackson and stay in Neal's face.
- With the triangle offense having discombobulated his offense, Blake is much more decisive and effective in Brown's more traditional strategies. His long-range bombs are tickling the nets, he's briskly moving the ball, and his defense is as spidery as ever. Ah, but can he keep up with Parker?
- The Lakers tendency to switch in defense of high screen/rolls usually creates blatant mismatches, which are then countered with quick double-teamings. Given SA's discipline, these adjustments have to be made super-quick and must be supported by precise weak-side rotations.
- L.A.'s most significant edges are in power, size and length. Bynum has to be a dreadnaught scorer (and make his free throws), and they must collectively assault the offensive glass.
- The Spurs will definitely pack the paint on defense and force the Lakers to beat them with their somewhat iffy perimeter shooting. Accordingly, Sessions, MWP, Blake, and Barnes must hit their treys, thereby compelling SA to extend their defense and giving Bynum more time and space to do what he does in the low-post.
- How many otherwise sure-fire layups will Splitter's bad hands cost the Spurs?
- Since World Peace is LA's second-best low-post scorer, how often will he be stationed on his preferred spot on the left box?
- If Parker and Duncan can successfully take their dribbles to the hoop at least a half-a-dozen times each, the Spurs will win.
- Can the Spurs limit LA's offensive rebounding to equalize their shot total with the Lakers?
- Will Bynum run all-out in transition-defense situations?


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text: Some Meijer customers received a huge surprise this week when they showed up to the pharmacy at the Grape Road store in Mishawaka. They arrived planning to dish out money for certain antibiotics they needed. But they walked away with their prescriptions without having to spend a dime. This comes in light of Meijer's announcement Monday that its 176 pharmacies will fill, without charge, prescriptions for seven generic oral antibiotics. "Definitely, it's a good service for the community," said Beth Longbrake, pharmacy team leader for Meijer, 5020 Grape Road. Any customers, regardless of insurance or co-pay, can take their prescription to any Meijer pharmacy and receive their designated antibiotic free of charge, the company said. The news is still coming as a surprise to many customers. Stacie Behler, spokeswoman for Grand Rapids-based Meijer, heard that one woman even started crying when she learned of the program. And local customers certainly haven't been procrastinating when it comes to taking advantage of it. The Grape Road store saw a number of people Monday, Longbrake said. "We definitely filled a lot of them." "I've even seen a number today already," she said early Tuesday afternoon. In addition to drawing in its regular customers, the store is even seeing some new faces, Longbrake said. But Meijer hasn't been the only major retailer rolling out a prescription drug program for customers recently. Wal-Mart Stores announced last week that it would offer $4 prescriptions for some generic drugs at its stores in 15 states, including Illinois and Indiana, after launching the program in the Tampa, Fla., area two months ago. The program is already available to customers here, according to the Wal-Mart pharmacy at 316 Indian Ridge Blvd., Mishawaka. And in May, Kmart, part of Sears Holdings Corp., started offering 184 generic prescriptions for $15 for a 90-day supply in all its 1,100 pharmacies nationwide. Meijer's newly launched program benefits consumers by covering at least one antibiotic from each major antibiotic classification. They make up at least 70 percent of the generic antibiotic prescriptions for children that Meijer fills, the company said. Certainly, free prescriptions come in handy at a time when health care costs are affecting many families across the country. "We know that's on the minds of Meijer customers," Behler said. And at a time of year when consumers are exposed to the cold and are more likely to get sick, it provides a means for people to get treated rather than easily passing on their illnesses to others. So how did the program come about in the first place? Over the last couple of years, a few stores in Fort Wayne and Toledo were selected to try out the program, which involved working with pediatric offices in the two markets, Behler said. And the program only involved Amoxicillin. Overall, the customer response to the program was positive, Behler said. Now she hopes the new free prescription drug program demonstrates Meijer's continued commitment to the communities in which it has stores, she said. When Meijer came up with the program, it wasn't looking at the costs, but rather the investment, Behler said. And, indeed, it's an investment that has drawn positive feedback from customers who are relieved that health care doesn't always have to burn a hole in their wallets. "Nobody likes to feel sick," Behler said. "And so when you are sick, this is just one way to make you feel a little bit better."


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Ozeki VoIP SDK - Product Guide
Did you know?This SDK was used to build:
Ozeki Phone System XE - VoIP PBX Software for Developers Which is a high performance PBX system supporting Mobile and Desktop phones.
It was also used to create Ozeki 3D VoIP softphone. A cool SIP client that allows 3D Video calls.
How to implement Noise Reduction?
This article is a brief introduction about implementing noise reduction in relation with Ozeki VoIP SIP SDK. After reading through this page you will be fully familiar with all the essential terms concerning noise reduction technology and what you will need for creating your own solution using Ozeki VoIP SIP SDK.
What is noise reduction? How does it work?
Noise reduction is the process of removing noise from a signal. All recording devices, both analogue and digital, have traits which make them susceptible to noise. Noise can be random or white noise with no coherence, or coherent noise introduced by the device's mechanism or processing algorithms.
In VoIP communication noise reduction plays a big part as the voice communication can contain loads of background noises. The background noises can be reduced with implementing some standard algorithms. Ozeki VoIP SIP SDK provides the basic noise reduction support that you can use in your VoIP solutions.
How to implement Noise Reduction using C#?
The noise reduction feature is implemented in Ozeki VoIP SDK in the AudioQualityEnhancer
class, which is a media handler. You can use the AudioQualityEnhancer object to set the noise reduction level to
Low, Medium, High or NoReduction. This can be done through the NoiseReductionLevel property.
To learn more about media handlers, please visit the Managing Media Handler article.
The AudioQualityEnhancer object can be initialized. As the object can also be used for acoustic echo cancellation, you can set the echo source for the object too.
The AudioQualityEnhancer is a MediaHandler that needs to be set in the audio transmission line of the softphone. The outgoingDataMixerobject is an AudioDataMixerHandler that is also needed for mixing the incoming data with the result of noise reduction and/or echo cancellation features.
Noise Reduction example in C#
using System; using Ozeki.Media; namespace Noise_Reduction { class Program { static Microphone microphone; static Speaker speaker; static MediaConnector connector; static AudioQualityEnhancer audioProcessor; static void Main(string[] args) { microphone = Microphone.GetDefaultDevice(); speaker = Speaker.GetDefaultDevice(); connector = new MediaConnector(); audioProcessor = new AudioQualityEnhancer(); audioProcessor.NoiseReductionLevel = NoiseReductionLevel.Medium; audioProcessor.SetEchoSource(speaker); connector.Connect(microphone, audioProcessor); connector.Connect(audioProcessor, speaker); microphone.Start(); speaker.Start(); Console.ReadLine(); } } }
Training guides, simple examples
If you would like to visit the detailed developer documentations, you can learn much more from the Ozeki VoIP SIP SDK Training chapter.
If you have any questions or need assistance, please contact us at firstname.lastname@example.com
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Getting started
Downloading VoIP SIP SDK
Installation steps
PBX configuration
Examples with source code
VoIP technology walkthrough
SIP softphone development
Webphone development
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Voice recording
Search the manual
API documentation


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I'd like to brag and say I get a lot of questions about my life. You know, like I'm George Clooney or Tiger Woods. The fact is, 99.9% of folks really don't care and who can blame them: we all have enough on our own plates!
However, I do get one question on a repeated basis from anyone who has even a nodding reference to my background. And I've gotten this question from everyone from (name drop alert), Bret Baier to Brit Hume. From family members to mild acquaintances.
And the question is: "Why did you quit golf?" Well, that's the question, but the underlying premise is "Why did you quit golf…when you were so good?"
Yes, that baffles people. I mean at the height of my powers I was anywhere from a "scratch" to 3 handicap. Now, don't get me wrong: I wasn't a national caliber amateur by any stretch. On the other hand, you could team me up with a Tour pro, Walker Cupper, or local hotshot and not tell much of a difference. In short, the kind of golfer who was good enough to think he could play in the U.S. Mid-Amateur, but ends up missing the qualifying score by 2 shots. (which, in fact, happened.)
But, in the eyes of most people, I was pretty darn good. And then I quit. Cold turkey, in fact, and it seems to both intrigue people and…kind of bug them.
I had my reasons, though, and they made perfect sense to me.
1. When I "retired" I had played non-stop for over 40 years. That's a lot of time to do anything.
2. I was far from mastering the game, of course, but without doubling my practice time, I wasn't getting any better.
Now, those sound good, but here's the real reason in a nutshell: It's a grind to be a good golfer. (Yes, I am fully aware that sounds like the whine of the rich guy saying ("it's a grind to be a millionaire!" But, bear with me.)
Now, maybe only golfers can relate, but whenever a low handicapper steps onto the first tee, he is expected to knock it 300 yard straight down the first fairway! He also can't slice one out of bounds, can't chunk an iron 40 yards, and certainly can't make double bogey. No, his handicap is a badge that says: I am VERY good, so bow down to my brilliance.
Truly, it's unlike any other sport. I suppose you can know a fellow tennis player's ranking, but it's not like the local hot shot will suddenly start hitting shots 30 feet over the baseline. The top skier won't start tumbling down the hill. The best cyclist won't all of a sudden have trouble going up a short hill.
But, in golf, yeah, I could have an awful round. Be a true hack. Or — egads! — not break 80. And I'd feel sick about it. Like I was some sort of poseur who professed to regularly shooting 70, but couldn't break 90!
Sure, it was self-imposed pressure, but it was pressure nevertheless, and I felt it almost non-stop for the past 30 years.
So, when I came to my last tournament, and the last shot of the last tournament — an extremely tricky downhill pitch to an uphill green off a super tight lie (for those keeping score) — I vowed if I could pull it off, I'd have proven to myself that I could "go out on top" and could therefore quit if I wanted.
I did pull it off, and haven't picked up a club in the past 4 years. That's a long time off from something you did daily since you were 10.
Still, I don't miss it.


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Showing Suppliers 1 - 2 of 2
Radwell International (19 Products)
Address: 283 Hughes Lane, St. Charles, MO
Business Type: Distributor, Service
Description: The Story of Radwell Brian Radwell, President and CEO explains it like this: "Radwell International sells and repairs industrial electrical and electronic control devices. We sell and repair timers, counters, photoelectric sensors, circuit breakers, pushbuttons, PLC's,... (more)
RS Electronics
Address: 149 Weldon Parkway Suite 109, Maryland Heights, MO
Business Type: Distributor
Description: RS Electronics is Now Part of Carlton-Bates Company The new, combined company, known as Carlton-Bates Company, is part of the Wesco Distribution, Inc. family of companies. Learn more about Carlton-Bates Company or get answers to frequently asked questions. Carlton-Bates Company is a trusted... (more)


text: Katherine Sherrod Morgan, 78, 600 W. Stetson St., Orlando, died Saturday. Born in Tuscumbia, Ala., she moved to Orlando from Miami in 1969. She was a retired registered nurse and a member of College Park United Methodist Church. Survivors: daughters, Mrs. Jean Gilliland, Orlando, Mrs. Joan Dixon, Indialantic, Mrs. Patricia Bender, Orlando, Mrs. Maria Francisco, Craig, Colo.; brothers, John R. Sherrod Jr., Jackson, Miss., Robert N. Sherrod, Nashville, Tenn.; 14 grandchildren; seven great-grandchildren. Baldwin- Fairchild Funeral Home, Orlando.


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Oh, 2016. You were a whirlwind. You killed off half of Hollywood. You gave us a presidential election that couldn't have been dreamed up by the producers of whatever that Kardashian show is called. 2016 was a year where the unexpected happened, sometimes in a big way, at some point for virtually everyone. What a great comfort, then, that God is in control, right?
Looking Back…
I had a great year with R. It was our first full year as a married couple, and I think the adjustment has gone well. She probably rolls her eyes a lot more now than she did when she was single, but I'm adorable, so that makes up for my antics. See? She just rolled her eyes again when she read that! We started out the year with the rough idea that we needed to get out of debt. We kind of knew what that looked like, so we started meandering down the path in more or less the right direction. By January, I had read The Total Money Makeover, R and I had listened to about half of the Financial Peace University CDs together, and we at least had a budget. We weren't very focused, though, and our progress (or lack thereof) showed it. I thought I knew better than the advice we had listened to, and I was a little selfish in wanting to get my debt cleared out before we turned our attention to our debt. After months of treading water, we finished FPU and decided to dive in, do it Dave's way, and really start attacking this beast. That's when we re-prioritized our debts, committed to working together and got rid of the "his" and "her" debt designations, elevated the budget past ornamental status, and started this blog as an accountability tool for it all. The final blow to what little frivolous spending we were still doing came this week, when our joint checking account finally(!) became a reality. Now, R will get a push notification on her phone every time I go through the drive-through, and I'll see the minute she walks out of Half Price Books with an illustrated Harry Potter book. After all, the buzzword of the decade is "transparency," right? Now that we can't hide those guilty little purchases from each other any more, even for a day or two, we can patch up the holes in our funnel and hopefully make even better progress in 2017.
…So We Know Where To Go
I think our biggest mistake this year was not having any goals to measure our progress by. All we had was, "Debt is bad." And that's not a bad mindset! In fact, I consider it much better than some our age who aren't even considering their financial situations, let alone analyzing them to see where they could improve. But in terms of attainable, measurable goals, "Debt is bad, let's get out of debt," is just… not one. So, for 2017, here's what we're planning to accomplish:
- Pay off R's car by June (goal moved up from original estimate of 11/17)
- Pay off Discover loan by September (goal moved up from original estimate of 02/18)
- Discover card down to below $1,000
If we can accomplish all that this year, that will represent over $10,000 paid off in one year. That leaves my student loans to be wiped out in 2018, and maybe some kind of miracle might happen where we could be completely debt-free at the end of 2019. The original estimate was February 2021, so having that done over a year early would be just peachy in my book.
Special Guest Author: Mrs. My Wife!
In the spirit of making this post about what we learned together this past year, I asked my beautiful wife if she had any input on what I had written before I posted this. To my surprise, she didn't just give me a point or two to try and work in, she wrote a whole thing! I don't think I can improve on it at all, so I'll just turn it over to her:
Getting into the flow of a budget is really hard and made me realize how selfish I am when it comes to the things I want. When we first started our budget, I was really excited because we had all this money set aside for our bills, date nights, and (the biggest category) student loans. After the initial excitement wore off and I would spend all my fun money or fast food money, I'd start pulling from other categories. I just HAD to go out to eat with friends; let's pull that from my clothing category, it's only $20. I really wanted a new mug or random item from Target; let's categorize that as student loans, what's an extra $10 missing. The thing is, just like eating out, those small pulls from other categories add up to a lot of missing money over a year. It's hard to admit but we probably could have paid off quite a bit more of our debt if I had been less selfish and harder on myself. And when my last pair of jeans finally bit the dust and I needed new ones, I wouldn't have had to shuffle around money because my clothing budget would have been full.
Getting into a budget is extremely freeing. Before we started this process, I was stuck in the paycheck-to-paycheck lifestyle that so many are experiencing. I was doing mental math every time I swiped my card because I wasn't sure if I had the money for rent or gas to drive two hours to see my boyfriend (editor's note: we started out our relationship living half a state apart while she was in school). But even though I was always worried about money, I never really did anything about it. Thankfully, Dave's program brought me to the light. Making a budget isn't hard. Paying down your debt isn't hard. Preparing for the eventual setback isn't hard. The difficult part is getting up and doing it, and once you do, the weight of that worry starts to get less and less. I am no longer doing mental math in the Price Chopper line trying to figure out if I have enough for groceries. When our cars need an oil change, I don't have to skip out on date night with my husband because we already have the money set aside. Are we swimming in extra cash? Obviously not. We still have a ways to go on this journey. But I am extremely thankful for the provisions God has blessed us with and am proud of my husband and the work we have put in this past year. I can't wait to see how we grow in the following years.
She's super great, guys. A beautiful, godly woman who once said, "Nothing says fun like fiscal responsibility"? Pretty much the perfect gal right there. Thank you for contributing, honey!
Remembering Who's In The Driver's Seat
Now that I've gone and told you all about my goals and plans for this next year, I'm reminded of James 4:13-15: "Come now, you who say, 'Today or tomorrow we will go into such and such a town and spend a year there and trade and make a profit'— yet you do not know what tomorrow will bring. What is your life? For you are a mist that appears for a little time and then vanishes. Instead you ought to say, 'If the Lord wills, we will live and do this or that.'" So in 2017, we'll work towards better financial responsibility with the understanding that our plans are not God's plans. Whatever He has planned for us is ultimately what will bring Him the most glory, so that's what we'll do. Have a Merry Christmas and a happy New Year, everyone!


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When was the last time you read "Little Women"? Have you seen the movie? I just watched it for the first time (the one with Winona Ryder) this last weekend and I'm thinkin' it might be a really good movie to share with pre-teen and teenage daughters. (OK, die hard literary folks might want their daughters to read it...but reading can be such a solitary process and watching a movie together has social benefits).
Now before you begin saying "they'll never watch THAT!", think about what they might learn if they did. The following messages are loud and clear:
- family matters--especially when times are tough
- the relationship between the sisters back then isn't very different from the conflicts between modern siblings
- the attitudes of teenagers (then & now) are just as "independent" and "testy"
- different "little women" have different criteria for choosing a boyfriend, husband or life partner
- staying true to your dream is important for a "happily ever after"
- smart girls are "cool"
So how do you encourage your daughters to watch this movie with you? Bribe 'em? Perhaps. Depending upon the age of your girls, you may need to dangle a little carrot. Some younger girls may just enjoy exclusive Mom/daughter time. But others may need a small incentive the first time you want to watch an "old" movie with them. You may consider an "if you watch with me then I'll ____". You might choose to watch a movie of their choice AFTER they watch "Little Women" with you. You might promise a trip to the Mall AFTER they watch "Little Women" with you. Some girls may even respond to a "treat" closer to home….an opportunity to talk with Mom where they get to do the talking.
Many kids think that movies are just for entertainment. And many are! But if you choose to focus upon a few nuggets in almost any movie, you may find at least one or two messages that can stimulate an important discussion with your children. When the movie is over you can explore what happened during the movie (the plot or events within the story)…or how the characters responded to challenges…or imagine what you would have done?
The more personal you make it, the greater value the experience will be. Don't frame the movie experience as "education" or ask them "what did you learn?" Instead, ask questions that allow your children to share their ideas and attitudes without interruption or criticism. And be on guard to "zip your lip" if you are tempted to tell them what they should have learned or taken away from the movie.


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Awaiting the completion of their new beach house, a family decides to stay in an abandoned mansion that is rumored to be the home of the terrifying 'Aswang.' The Philippines has several legends, but this by far is the scariest.
Actor: Michael Laurin, Shannon Laurin, Bryan Billy Boone, Shelene Atanacio
Director: Michael Laurin
Country: United States
Duration: 85 min
Quality: HDRip
Release: 2018
IMDb: 4
Keywords: aswang