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Press Release
CONTACT: Catherine Abbott, 760-245-4271 ext 2523 email@example.com
Victor Valley College Foundation receives $146,211 grant from the San Manuel Band of Mission Indians to purchase innovative technology for Emergency Medical Services Programs.
The San Manuel Band of Mission Indians recently granted $146,211 to the Victor Valley College Foundation to help enhance emergency responder training provided at the Victor Valley College Regional Public Safety Training Center.
Thanks to San Manuel's generous grant to the HEART, Healthy, Engaged, Active, Responsive and Trained project, faculty in the Emergency Medical Services (EMS) program will now be able to purchase two CAE "cut-suits" for a new type of trauma simulation lab. The suits are the most realistic way to simulate the look, feel and smell effects of severe trauma events on a live human while allowing students to safely treat and diagnose the three primary causes of death, uncontrollable hemorrhage, airway compromise and tension pneumothorax or a collapsed lung.
"The cut suits are a new state-of-the-art addition to our simulation program," said Victor Valley College's EMS Director Dave Olesen. "The tribe's generosity continually provides innovative technology and equipment to our students. However, this type of advanced training will greatly enhance workplace knowledge for our students who are currently working or eventually seeking employment."
The cut suits can be worn in any intensely physical simulation scenario on campus, under clothing and uniforms. They feature repairable skin and organs allowing user created and customizable wounds. Because of their durability and design, the user can also repair the suit, keeping maintenance costs at a minimum in future years.
"This is truly Hollywood's special effects meeting high fidelity simulation," said Olesen.
Additional funds will be used to pay for warranties to keep the simulation program running. Mannequins acquired in previous years are beginning to show their wear and tear from previous high use and high stress training. San Manuel's generous investment will help pay for those much needed repairs. Finally, their gift will allow the program to purchase an ALSi emergency training tool. This will allow the program to enhance and expand the use of Electrocardiograms purchased with funding provided by San Manuel in 2016.
"Through this gift, San Manuel is investing in advanced trauma training for our first responders to more effectively safeguard lives in San Bernardino County," said San Manuel Chairwoman Lynn Valbuena. "As a Native Serrano people whose aboriginal lands include the High Desert, we are pleased to work with Victor Valley College to benefit multiple communities throughout these lands we hold as sacred."
Victor Valley College Regional Public Safety Training Center is a $31.5 million, state-of-the-art training complex specifically designed to support students in the Administration of Justice, Fire Technology, Emergency Medical Services and Correction programs. It provides students a unique and far reaching training opportunity for cooperative emergency scenario cross-training exercises experienced by first responders every day in the normal course of the job.
For more information about Victor Valley College and the programs available at the Regional Public Safety Training Center, visit www.vvc.edu. To learn about the San Manuel Band of Mission Indians, visit www.sanmanuel-nsn.gov.
The Victor Valley College Foundation is a charitable organization that makes friends and raises funds to help Victor Valley College better serve its students and community. Visit www.vvcfoundation.com or find us on Facebook to join the growing number of people and organizations who contribute to support our mission


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subset: commoncrawl


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Read to your child.
Read to her from the day she is born.
Read to her every day.
Read to her until she can read her first word, then let her share in the reading.
As she can read more, encourage her, and read less yourself.
Hear your child read – listen to her read.
Let her know you are listening.
This is good practice, not just practice for a child's reading, but
practice for a parent's listening.
Read to your child… Jhciacb
If you are not already a subscriber, please scroll up and do so. Tell your friends about me — about what happens when I push the STOP button on the blender in my head. Oh, and there's this from Aerosmith. Enjoy…


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The war still has a lot of public support. And the situation is far from irretrievable. War-hawks want to portray the situation as something akin to the late stages of Vietnam, with a defeatist press and establishment, a war-weary public, and a few brave souls who've read their Churchill and remember the lessons of Munich wanting to stick it out.
But that's not where we are. What you've got is a lot of people who are unhappy about the administration's dishonesty, an equal number who don't think the current plan is working, and a pretty broad consensus that we need to make some course corrections if we're going to be successful.
So let's make those course corrections and give ourselves a shot at an outcome which is good for us and the Iraqis.
One thing we shouldn't do is give those liars a chance to question people's moral fiber for not signing on to their latest fairy-tale, the never-ending-story about why we did all this in the first place. Let's write those folks out of the conversation entirely.
Indeed. Course corrections are necessary. But why is not even one Presidential candidate suggesting what those corrections might be. I would think it is a better way to show that you support the country and its armed forces but are opposed to the sitting Administration. Instead, we get G.W.B. and a bunch of people who cannot decide whether they always opposed the war, oppose it only after they themselves voted for it, or oppose it on even days that are partly cloudy with a 15% chance or rain and support it on odd days with sunshine, leaving the rest of the calendar open for daydreaming.


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John Shearer/WireImage.com
Somewhere between her right frontal cortex and wherever it is she stores the names of Sanrio characters, Mariah has squirreled away the term prenup, and, despite speculation, she reportedly has put it to use.
Mariah apparently told a friend that anyone who thinks she and Nick Cannon didn't have a prenup "is smoking something!"
Sorry, Nick. Better love up that Barbie Dream House while you're still living in it.


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Hotels in Torre Alháquime, Spain
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Torre Alháquime overviewWhatever your interests are, Torre Alháquime has something for you. Though Torre Alháquime might not have many well-known attractions, you don't need to venture far to visit Olvera Castle and Parish Of Our Lady Of The Incarnation. In the surrounding area, you won't want to miss out on seeing Iglesia de Nuestra Senora de la Encarnacion and Acinipo Roman Ruins.
Where to stay in Torre AlháquimeWhether you plan to stay for a night or a week, Torre Alháquime has the right hotel for you. You can shop as many as 44 deals for Torre Alháquime accommodations on Hotels.com, some with discounts of up to 25%. Our room prices start at 15 USD per night and here's a breakdown of hotels by star rating in Torre Alháquime as well as in the surrounding area:
- • 29 4-star hotels from 48 USD per night
- • 58 3-star hotels from 43 USD per night
- • 24 2-star hotels from 19 USD per night
What to see around Torre AlháquimeHere are some recommended places to see in the surrounding area:
- • Olvera Castle (2.6 mi/4.3 km from the city center)
- • Parish Of Our Lady Of The Incarnation (2.7 mi/4.3 km from the city center)
- • Iglesia de Nuestra Senora de la Encarnacion (4.2 mi/6.8 km from the city center)
- • Acinipo Roman Ruins (5.5 mi/8.8 km from the city center)
- • Dolmen de los Tomillos 1 (6 mi/9.6 km from the city center)


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There's nothing like living by the ocean to make you feel alive. One of my favourite things to do is to head down to the beach when Curt gets home from work and take a walk together as a family, feeling the sand underfoot, the wind blowing our hair and salt on our lips. Often Curt surfs while we play on the beach and watch, or if the waves are smaller he takes Lila out on her little board. When it's flat then we dig or build palaces and collect shells. I feel so lucky to be able to do this and give the girls an appreciation and respect for the water and nature.
We've been even more lucky for the past couple of weeks as my parents have been visiting from England, so we've been able to share with them all that we love about living here. Today we had to say goodbye until we see them again in a year. Until then I will just have to treasure all the memories we made and throw myself back into daily life and working on our home and garden.
Next week the new term starts and Lila will begin kindergarten. I will begin painting again. My new easel, my best Christmas gift, has been sitting patiently waiting for me to find the time to pick up my brushes again and create just for the love of it. I also have a new Etsy shop waiting to be filled with images and listings of all my necklaces so I will be keeping busy to help to ease the emptiness and the inevitable void that is left behind after the farewells have been said and the aeroplane has departed.
Photos taken by Curt.


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How You Might Feel After Art of Mentoring
"Transformational. Feels like the most important stuff I've ever learnt about"
"Big life-changer – off the chart good"
"Ultra professional and transformative – for real. A most skilful construction of the process. Fully in line with the content that opened my eyes. A deep bow of gratitude."
What's the Ring 1 (Village Welcome) Programme?
Ring 1 – Village Welcome is a nature-based programme to deepen your connection to self, others and nature. Our culture repair model uses powerful practices from healthy, nature-based cultures worldwide.
How You'll Grow On Ring 1
You'll experience how a connected, regenerative?culture feels and understand how to create it and weave it into your own life and community.
What'll You Do and Who Will Guide You?
Lose yourself in the woods, find your playful side in games on the land and open your heart and senses more deeply through:
- storytelling
- time on the land
- reflection and discussion
- skillshares
- small group activities
In this week of Scottish summertime splendour you'll be wrapped in a fun and transformative cultural container that brings out the best in everyone. You'll be guided by an international team of open-hearted, creative and wild-wise facilitators.
Who Created the Art of Mentoring?
The Art of Mentoring was developed by Jon Young and the 8 Shields Institute. Its seven generations mission is to support everyone through effective culture building – helping people to be mindful, happy, full of vitality, focused, empathetic, truly helpful, fully alive and compassionate and loving.
Is Ring 1 For You?
The skills and practices from ring 1 can support people of walks of life and ages to be more connected, happier and healthier. They're especially useful for:
- Parents
- Teachers and outdoor educators
- Coaches and mentors
- Community creators and culture designers
- Facilitators
Essential info
- Prerequisite: none
- Age: all ages and life stages 18 or over are welcome
- Number of places: 72
- Arrival: 3 – 5pm Sunday 28th July
- Investment price: £590 (payable in instalments)
- Limited Early bird tickets available before 28th February
- Limited bursary places available, apply before 25th January


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DOTHAN - Author and historian Dale Cox will discuss his latest book, "Milly Francis: The Life and Times of the Creek Pocahontas," at Troy University's Dothan Campus on Sunday, Oct. 19.
The event will be held in the Harrison Room in Malone Hall starting at 3 p.m. Admission is free and open to the public.
Cox, the author of thirteen books on U.S. history, lives near the historic community of Two Egg, Fla. He has written extensively about Southeastern U.S. history from the era of Spanish exploration to the troubled times of the 1930s. His books have achieved critical acclaim and rank among the best-selling nonfiction books on history. He is currently featured by Troy University Public Radio in an ongoing interview series on the history of Northwest Florida.
His latest work is the story of Milly Francis, a young Creek Indian woman born in Alabama around 1803 who lived through three wars, including the First Creek War that destroyed her father's religious movement. During the Seminole War of 1817-1818, Francis saved the life of American soldier Duncan McCrimmon, an act that led Congress to present her with a special medal of honor. Though her actions altered how the American nation thought about Native Americans, it did not save her from a long and tragic journey on the "Trail of Tears."
The event is sponsored by Troy University's Wiregrass Archives and the Historic Chattahoochee Commission. For more information, contact Wiregrass Archives Director Dr. Marty Olliff at email@example.com.


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The ALS project is developing technologies with the intent to improve the productivity and reduce the cost of mass excavation. In a typical mass excavation application, a loading machine digs material from a face and dumps the material in a truck, with a throughput of hundreds of trucks per day. The process is repetitive and continues day and night and in most weather conditions. The type of loading machine and truck can vary, as can the material to be loaded which may range from sand to hard rock. Other issues include maintaining safety of all machines and personnel in the loading area and coordination of multiple machines to achieve a prescribed goal.
Last-Modified: Jan 15, 1997


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Wind Catcher Energy Connection Map
Wind Catcher Facility Details
Approximately 300,000 acres in Cimarron & Texas Counties, Oklahoma, home to some of the best wind in the country. Approximately 98-99% of land in the project site area will remain in agricultural use, supporting a primary industry in the region.
2,000 megawatts
Eight hundred GE 2.5 megawatt turbines designed to enhance siting efficiency, offer industry-leading reliability and allow for higher energy production. All machine heads and hubs will be manufactured in the U.S., and additional components will be manufactured in Louisiana, Arkansas, Texas, and Oklahoma.
Construction began in 2016. The project is expected to be operational by mid-2020.
Invenergy is leading the development, engineering, equipment procurement, construction and financing of the Wind Catcher facility.
American Electric Power (AEP) utility subsidiaries Public Service Co. of Oklahoma (PSO) and Southwestern Electric Power Co. (SWEPCO) are asking utility regulators in four states to approve plans to purchase the wind farm from Invenergy upon completion of construction and to build the power line.
Invenergy is contracted to operate and maintain the project.
To avoid and minimize impacts to wildlife and other natural resources, Invenergy is working with state and federal agencies and other interested stakeholders to site, build, and operate facilities responsibly. All actions are in accordance with the U.S. Fish and Wildlife Service's Land-based Wind Energy Guidelines, which include robust pre-construction wildlife and habitat surveys, early and frequent communication with wildlife agencies, and operational monitoring to minimize risk to wildlife.
Wind Catcher Power line
An approximately 350-mile dedicated power line will connect a substation at the wind farm with a substation near Tulsa to deliver the wind energy to customers.


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Excellence in Custom Built Bathroom Design
The 2018 Awards of Excellence pertain to projects launched or ongoing in the 2017 calendar year. However, the project does not have to remain on the market at the time that the Awards package submissions are due. Builders, professionals, suppliers, manufacturers, trade contractors and any other DRHBA member are eligible to submit applications for the Awards of Excellence pursuant to the following eligibility requirements:
- The applicant must be a member in good standing of the DRHBA as of December 31, 2017 in order to submit an application.
- The applicant must be a member in good standing of the DRHBA on the night of the Awards of Excellence in order to receive an award.
- All entries must be for projects active between January 1 and December 31, 2017.
- All projects must be located in the Durham Region.
1. Description of project
2. Photos
Maximum of 5 photographs showing different views.
3. Clean copy of floor plan (PDFs)
5. Project Name
6. Municipality
7. Address
8. Postal Code
9. Date the project opened for sale
10. Who helped you?
Specify person and/or company (must be a DRHBA member company).
11. Link to video (optional):
You may add a link to a video you have uploaded to YouTube or Vimeo to showcase your product.


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Navguide: Aids to Navigation Manual
Year: 2014
Language: english
Author: IALA-AISM
Genre: Manual
Publisher: IALA-AISM
Edition: 7th
Format: PDF
Quality: eBook
Pages count: 259
Description: Document give a detailed overview of a specific topic. Currently this includes: NAVGUIDE; VTS Manual; and Preservation Manual. The NAVGUIDE covers all aspects of Aids to Navigation (AtoN) and is updated every four years at each IALA Conference. The VTS Manual covers all aspects of Vessel Traffic Services and is updated every four years at each Symposium.
|zxc писал(а):
2018 edition https://seatracker.ru/viewtopic.php?t=28054


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The most effective cure for a minor staph infection is treatment with antibiotic ointment or oral antibiotics, according to MedicineNet. Severe staph infections may require intravenous antibiotics, while staph infections involving abscesses may require surgical draining, and deeply affected tissues may require surgery.
Minor staph infections in the skin are generally recognized by their appearance and treated with an antibiotic ointment; however, some skin infections require treatment with an oral antibiotic. Intravenous antibiotics are administered to patients with life-threatening staph infections. The treatment of severe staph infections may involve the use of laboratory testing to determine the appropriate antibiotic to eliminate the bacterial infection. Tissue, blood and body fluids may be cultured as part of the laboratory testing, reports MedicineNet. These diagnostic tests are commonly used for patients who have staph infections of the bloodstream or who have pneumonia or endocarditis.
The type of antibiotic used to treat a staph infection depends upon how drug-resistant a specific bacteria is and the severity of the infection being treated. Vancomycin, telavancin and oxacillin are among the types of antibiotics used to treat staph infections. Doctors may also use sulpha drugs to treat a staph infection. In some cases of deep staph infections affecting muscles, surgical treatment is necessary to rid the body of the infection, explains WebMD. As of 2015, staph infections are becoming increasingly resistant to antibiotic treatment, according to MedicineNet.


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Kentucky Artisan Center at Berea
Alice Lloyd College Professor Carves Wheel-Thrown Pottery Sept. 26 at Kentucky Artisan Center at Berea
On Saturday, Sept. 26, Alice Lloyd College professor Mike Ware will be throwing pottery on the wheel and carving the clay surface with intricate patterns from 10:30 a.m. to 3:30 p.m. at the Kentucky Artisan Center at Berea.
Ware creates his pottery on a potter's wheel from stoneware clays. He often decorates his forms with images such as dogwood flowers, influenced by the woods near his home. He decorates his pottery using an incising tool that cuts away clay and leaves intricate texture and openings in the form. Color is added using mineral oxides mixed with clay and brushed onto the surface before glazing and firing.
Ware was born and raised in Sunbury, Pennsylvania, and attended school in nearby Lancaster, Pennsylvania. He received his Bachelor of Science degree in art education from Millersville State University. Ware came to Kentucky to attend Morehead State University, where he received a Master of Arts degree in studio arts in 1974. Upon graduating, he accepted a teaching opportunity at the Hindman Settlement School in eastern Kentucky, where he oversaw the operation of the clay studio at the school.
Photos, left to right: Mike Ware demonstrates pottery at the center; Ware carves a leaf into the clay rim of a bowl; a finished bowl with dogwood carved rim by Mike Ware
In addition, Ware taught art to levels K-12 in both Knott and Letcher counties from 1975-1991. In 1992, after a year off from teaching public school, he joined the faculty at nearby Alice Lloyd College, where he now teaches art for the school's education majors as well as classes in the humanities.
Pottery by Ware is regularly available at the Kentucky Artisan Center at Berea, 200 Artisan Way, just off Interstate 75 at Berea, Exit 77. The center's exhibits, shopping and travel information areas are open daily, year-round, from 9 a.m. to 6 p.m., with the cafe open from 9:30 a.m. to 4 p.m. Admission is free.
The center currently features works by more than 700 artisans from more than 100 counties across the Commonwealth. A gallery exhibit, "It Takes Two: Collaborations by Kentucky Artisans." is on display through Feb. 27, 2016, and in the lobby "Weaving in Kentucky: A Continuing Tradition" is on display through Nov. 14. For information about the center's events call 859-985-5448, visit us on Facebook at www.facebook.com/kentucky.artisan.center, or go to the center's website at www.kentuckyartisancenter.ky.gov.
Kentucky Artisan Center at Berea is an agency in the Tourism, Arts and Heritage Cabinet of the Commonwealth of Kentucky.


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With stunning canyon vistas, spectacular rock outcroppings and mountains as jagged as a crocodile's tail, Malibu Creek State Park is a delightfully wild place to pitch a tent and investigate on foot -- and it's only 25 miles west of downtown Los Angeles and just six miles from busy Pacific Coast Highway.
The 6,000-acre park in Calabasas is a particularly good place to hike and mountain bike, with miles of trails and dirt roads that wind to numerous year-round ponds and streams and to a lake flanked by waving cattails and chaparral-covered slopes.
An excellent introductory hike begins at the edge of the campground and snakes 3.5 miles to the lake and back. Just follow the Shady Trail signs down a dirt fire road, past a creek and up a valley till you reach a visitor center (open noon to 4 p.m. weekends).
From the visitor center, take the George Trail upstream to where it rounds sky-scraping walls of volcanic rock. At the site is a lovely rock pool and beyond that is Century Lake. If the setting seems familiar, it might be because it was used as a film location for Tarzan movies and "The New Swiss Family Robinson." Parts of "Planet of the Apes" was filmed nearby.
Malibu Creek State Park is also one of the last tangible places on Earth to reconnect with Margaret "Hot Lips" Houlihan, Dr. Benjamin "Hawkeye" Pierce, "Trapper John" McIntyre and other characters of "MASH," the dark-comedy weekly TV series that spanned 11 seasons and followed a team of surgeons and support staff during the Korean War.
The show was filmed on land that had been the property of 20th Century Fox Studios before the state purchased it in 1974.
Parts of the set can be viewed after hiking 2.3 miles on a mostly flat dirt road that starts at the day-use parking lot, hugs a creek bed and wanders through picturesque thickets of valley oaks and grasslands flush with birds -- habitat that has changed little since the Chumash settled here thousands of years ago.
All that remains of the set are the rusty hulks of a Dodge WC-54 ambulance and a Willys Jeep, and above them a flat dirt landing pad where choppers carrying the "wounded" landed.
Except for helping boomers take a stroll down memory lane, the site is seldom used today. Law enforcement occasionally puts a chopper down on the site.
The campground is in a serene valley and contains 62 tent campsites, two wheelchair-friendly bathrooms with flush toilets and solar-heated showers, and four RV campsites. Most of the sites are in the sun, which is fine at this time of year but can be uncomfortable in summer. The campground is best visited during fall, winter and spring.
The top campsites, for privacy and shade, are 27 and 24, followed closely by 7, 17, 21, 22 and 39; all offer the option of pitching a tent under a majestic oak. Every campsite contains a fire pit and picnic table but no hookups.
Campers, be sure to rise early. If you do, you'll very likely see deer nibbling on grass in the fields near the campground. They are used to seeing bipeds, so it's easy to get within 100 feet of them to take a picture or just to watch them dine.
Comments? Email firstname.lastname@example.com


text: Stores DealerProfile TWO SEAS Easy to find near 540 W and Hwy 70W on Westgate Rd near Westgate Jeep. Shaw believes in its people, products and partnerships. Our flooring retailers are committed to providing the best service they can. They go above and beyond to make sure you're satisfied with the product, service and ultimately, your home. Purchasing flooring can be daunting, but our retailers are there to help you every step of the way. Shaw Industries is committed to creating a better future – for our customers, our people, our company and our communities. We know our retailers feel the same way. View all stores


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A woman who was arrested outside Tom Cruise's home on Thursday for violating a restraining order is the same person who has been accused of stalking actor John Cusack.
Emily Leatherman, 32, was apprehended by officers in front of Cruise's Beverly Hills residence at 3:36 p.m., Sgt. Mike Foxen tells PEOPLE.
"Leatherman just showed up, and Tom Cruise's security called the police," Sgt. Foxen says. "Cruise had a standing restraining order against her.
"We determined that she is a transient without a residence," Sgt. Foxen added. "She was cooperative, and is currently in jail at the Beverly Hills station."
Last July, Cusack was granted a temporary restraining order against Leatherman at a Santa Monica court.
Cusack's legal filing said that Leatherman "is showing unusual interest by stalking, throwing long letters of interest over my fence in bags with rocks and screwdrivers inside, making unannounced visits to offices of people I work with in an attempt to meet with me and listing my address as her own during a recent arrest."
She also "threatens to commit acts of violence against herself if I do not help her," according to papers filed by Cusack.
In regard to the Cruise case, Leatherman is scheduled to be arraigned Monday, and her bail was set at $45,000.


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You are currently browsing the monthly archive for December 2012.
The club will be having a meeting on January 20, 2013 at the Huron Point Sportsman Club at 11:00 AM. There will be an election of officers and a presentation of awards from the 2012 year. Following the meeting there will the annual pot luck luncheon. Please notify Steve Pittiglio or Don Williams of any titles achieved this past year as soon as possible in order to present them at the meeting. If you are coming to the luncheon or bringing a dish to pass notify John Nowakowski–586-790-3485. The club is located at 35800 E. Twenty Eight Mile Road, Lenox Michigan 48050 Phone: 586-749-5420.
There will be a club meeting at the Huron Point Sportsman Club at 10:30 AM, Saturday December 15, 2012. This will be the last meeting of the year. We will be going over a few issues. Please try to attend. The Club is at 35800 E. Twenty Eight Mile Road, Lenox, Michigan 48050. Phone–586-749-5420. The trap, skeet and sporting clays fields are open to the public.


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The best of both worlds, House is clean and allows malt and hops to shine. This strain is extremely versatile and flocculent enough to drop out of the beer quickly. Best used in American IPAs but works well in English style ales. House is clean at cold temperatures with increased esters as fermentation temperatures increase.
Temp: 62-70F, 16-21C // Flocculation: High // Attenuation: 73-75%
Ready to attack your IPA, Barbarian produces stone fruit esters that work great when paired with citrus hops. Barbarian will give you what you need for an exceptionally balanced IPA.
Temp: 62-70F, 16-21C // Flocculation: Medium // Attenuation: 73-74%
A craft brewing standard, Flagship is a versatile strain loved for its extremely clean character. This strain performs well at standard ale temperatures, but can be used in the low 60s to produce exceptionally crisp ales. Flocculation is in the middle of the road and will typically require filtration or fining to achieve crystal clear beers.
Temp: 60-72F, 16-22C // Flocculation: Med-low // Attenuation: 73-77%
Brewers swear by this strain to achieve super bright ales in a short amount of time. One of the most flocculent brewer's strains around, Pub will rip through fermentation and then drop out of the beer quickly. Pub produces higher levels of esters than most domestic ale strains. Be sure to give beers made with Pub a sufficient diacetyl rest.
Temp:64-70F,18-21C // Flocculation: Very High // Attenuation: 69-74%
A beautiful strain for stout, porter, brown, and amber ales. Darkness produces a unique character that matches up perfectly with roasted and caramel malts. This strain is alcohol tolerant, so don't hesitate to throw high gravity worts its way.
Temp: 62-72F, 17-22C // Flocculation: Medium // Attenuation: 71-75%
Independence is the strain for bringing some new character into your hop-driven beers. Higher in esters than Flagship, this yeast will give some fruit character that will take your hoppy beers to a new level. While it shines in pale ales and IPAs, Independence is a great all-around strain and will also work well in stouts and English ales.
Temp: 60-72F, 16-22C // Flocculation: Medium // Attenuation: 72-76%
This strain is a fast mover and can be used at the low end of the ale fermentation spectrum to keep it clean. Joystick is a good choice for big, high alcohol, malty beers but has no issues chomping on a hoppy double IPA.
Temp: 60-70F,16-21C // Flocculation: Med-High// Attenuation: 73-77%
Citrus cranks out orange and lemon aromas along with some tropical fruit. Use this strain at high temps for big ester production. A wild saccharomyces strain, it will get a bit funky without the worries of a brettanomyces strain.
Temp: 67-80F, 19-27C // Flocculation: Low // Attenuation:74-78%
This strain tests positive for the STA1 gene via PCR analysis and is therefore considered to be Saccharomyces cerevisiae var. diastaticus
Dry Hop is a blend of A20 Citrus and A04 Barbarian. When this blend goes to work on your hoppy beer, the hop aroma blows up. The combination of these strains produces amazing aromas of citrus, peach and apricot that will accentuate your IPA, pale ale, and any other hop driven beer.
Temp: 64-74F, 18-23C // Flocculation: Medium // Attenuation: 74-78%
This blend contains a strain that tests positive for the STA1 gene via PCR analysis and is therefore considered to be Saccharomyces cerevisiae var. diastaticus.
Tartan is a traditional strain that accentuates the malt character of Scottish ales. It can also be used for other styles and works well in IPAs due to its clean character. For a higher ester profile, use this ale yeast at the top end of the temperature range.
Temp: 65-70F, 18-21C // Flocculation: Medium // Attenuation: 70-75%
Juicy. Fruity. Juice is an amazing strain for East Coast IPAs. The ester profile of Juice brings out the aromas and flavors of the new school hops and creates a beer that is greater than the sum of its parts. Keep an eye on this strain, it likes to move to the top of fermentation and will climb out the fermenter if too full.
Temp: 64-74F, 18-23C // Flocculation: Medium // Attenuation: 72-76%
This strain has demonstrated the need for higher wort dissolved oxygen (DO) levels than most ale strains. Target 20-25 ppm DO or set the oxygen regulator flow to 50% higher than normal.
This is the traditional German strain used to produce world class weizen beers where big banana aroma is required. Balanced with mild clove, depending on your wort profile, this strain will produce amazing beers. Stefon will create a slightly higher level of acidity to give your beer a very crisp finish. Slightly underpitching will help increase the banana character.
Temp: 63-73F, 17-23C // Flocculation: Low // Attenuation: 73-77%
A traditional alt strain, Kaiser is ready to produce an array of German style beers. It will keep the beer clean and allow the delicate malt flavors and aromas to shine through. Characteristics of this strain make it a good choice for traditional Berliner weisse fermentations. Kaiser is a low flocking strain, so expect long clarification times, but very low diacetyl levels.
Temp: 56-65F, 13-18C // Flocculation: Low // Attenuation: 73-77%
Dieter is a clean, crisp, traditional German Kölsch strain. A very low ester profile makes this strain perfect for Kölsch, Alt and other light colored delicate beers. Dieter has better flocculation characteristics than most Kölsch strains which allows brewers to produce clean, bright beers in a shorter amount of time.
Temp: 60-69F, 16-20C // Flocculation: Medium // Attenuation: 73-77%
A traditional Norwegian strain that has an extremely wide fermentation temperature range. This strain has been traditionally used in farmhouse style beers however, due to it's fermentation temp range can be used in a variety of beers from pseudo lagers, Belgian inspired and hop forward beers. On the cool end of the range Loki is super clean; producing little to no esters and phenols. As things warm up, it tends to produce a huge fruit ester profile.
Temp: 65-100F, 16-37C // Flocculation: Med-High // Attenuation: 75-85%
This is the strain for Belgian Wit style beers. Whiteout produces an excellent balance of spicy phenolic character and esters. Along with the necessary aromatics, this strain produces a significant amount of acidity which is perfect for wits and other light colored Belgian ales. Whiteout can be flocculent during fermentation, then become non-flocculent at the end. This may lead to slower than normal fermentation.
Temp: 62-72F, 17-22C // Flocculation: Med-low // Attenuation: 72-76%
Gnome is the yeast for brewing Belgian inspired beers in a hurry. This strain is extremely flocculent and drops out of the beer quickly after fermentation. Gnome produces a nice phenolic character that goes well with hops, as well as with caramel and toffee flavors. Great for Belgian ales that need to be crystal clear without filtration.
Temp: 65-75F, 18-24C// Flocculation: Med-high // Attenuation: 72-76%
The perfect strain for your classic abbey ales. Triple Double produces moderate esters with low to no phenolic characteristics. This strain is tried and true and works perfectly in a production environment. Keep an eye on Triple Double, it likes to sit on top of the wort throughout fermentation which may result in a slow fermentation.
Temp: 65-77F, 18-25C // Flocculation: Medium // Attenuation: 74-78%
Saison…no problem. Belgian stout, double… yep. Workhorse is the strain to use for a wide variety of brews. Super clean, this fast-attenuating strain has good flocculation characteristics. High alcohol tolerance makes this a great option for big Belgian beers.
Temp: 65-75F, 18-25C // Flocculation: Medium // Attenuation: 72-77%
This unique yeast can be used in your saison, farmhouse ale, or other Belgian styles where high ester levels are important. Rustic typically produces a lot of bubblegum and juicy aromas that compliment complex maltiness.
Temp: 68-80F, 20-27C // Flocculation: Medium // Attenuation: 72-76%
This strain tests positive for the STA1 gene via PCR analysis and is therefore considered to be Saccharomyces cerevisiae var. diastaticus
This strain is a beautiful yeast for fermenting abbey ales, especially quads; high alcohol and dark Belgian beers. Monastic will produce beers with a high level of phenolic character and esters. It can be slow to begin fermentation but will easily dry out high gravity worts. This strain is a low flocking strain, so expect it to stay suspended for a long time.
Temp: 68-78F, 20-26C // Flocculation: Medium low // Attenuation: 74-78%
This yeast is an insane wort attenuator. Napoleon will destroy the sugars in your saison and farmhouse beers – even the ones in which most brewer's strains have no interest. When all is said and done, Napoleon produces very dry, crisp beers with nice citrus aromas. Yeast settling times can be long, usually requiring filtration for bright beers.
Temp: 65-78F, 18-26C // Flocculation: Low // Attenuation: 77-83%
This strain tests positive for the STA1 gene via PCR analysis and is therefore considered to be Saccharomyces cerevisiae var. diastaticus
This strain is for fermenting your "California Common" beer. Cablecar can produce clean pseudo lagers at ale temperatures but is also willing to work as a traditional lager strain down to the mid-50s.
Temp: 55-65F, 13-18C // Flocculation: Med-high // Attenuation: 71-75%
The world's most popular lager strain is ready for you. Global is an all-around solid lager strain that produces clean beers with a very low ester profile. This strain is very powdery, so long lagering times or filtration is required for bright beer.
Temp: 46-56F, 8-13C // Flocculation: Med-low // Attenuation: 73-77%
This strain combines good flocculation characteristics with low sulfur and low diacetyl. Clean fermentations produce amazing bock, helles, pilsner, dunkles, and just about any other lager style you throw its way.
Temp: 50-60F, 10-16C // Flocculation: Medium // Attenuation: 70-74%
A traditional Czech lager strain, Urkel allows for a nice balance between hops and malt. This strain can be slightly sulphery during fermentation, but it cleans up during lagering. Fermentation at the higher end of the range will produce a beer with minimal sulfur and a light ester profile.
Temp: 52-58F, 11-14C // Flocculation: Medium // Attenuation: 71-75%
Sour Batch Kidz is a blend of low attenuating Belgian saison yeast, Lactobacillus, and two Brettanomyces yeast strains. This blend is great for emulating lambics, Flanders reds, sour farmhouse ales and any other brew you would like to funk up.
Temp: 68-76F, 20-24C // Flocculation: Low // Attenuation: 80%+
This blend contains a strain that tests positive for the STA1 gene via PCR analysis and is therefore considered to be Saccharomyces cerevisiae var. diastaticus.
Suburban Brett is Brettanomyces yeast that works great as a secondary aging strain. It really shines when used in wood barrels and will produce complex and balanced aromas of sour cherry and dried fruit. It can also be used for as a primary strain for brett only beers
Temp: 64-74F, 18-23C // Flocculation: Low // Attenuation: 75-80%


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So Bad They're Brilliant: Congo
Want to see the very definition of a bungle in the jungle? Then blow the dust off the stupendously stupid and ridiculously enjoyable Congo, the 1995 movie version of novelist Michael Crichton's potboiler, in which a gorilla talks, paints, smokes a cigar and downs a martini while fellow actors make utter ass monkeys of themselves.
From a truly goofy, take-the-money-and-run screenplay by John Patrick Shanley (Moonstruck; Doubt), this Africa-set misfire has something to do with a planeload of cardboard characters heading to the Congo for assorted daffy reasons including a quest for the legendary diamond mines of the Lost City of Zinj. The ship of fools includes a primatologist (zombified Dylan Walsh) aching to return a chatty, humanized ape to her homeland; a shady Romanian businessman (Tim Curry, in full-on camp mode adopting a bizarre Peter Lorre-esque accent) who is convinced that imagery in the talking ape's paintings will lead to the fabled diamond mines; and a chilly former CIA goon and PhD turned communications monopoly goon (Laura Linney, duller and whiter than even Laura Dern in Jurassic Park) who brings along handguns, machine guns, laser guns, stacks of cash, satellite transmitters and, just for laughs, a hot-air balloon.
Walsh and Linney get off on bad footing when Linney insists on horning-in on his trip to Africa. "Name your price," she says, to which Walsh volleys back, "I don't have a price! I'm not a pound of sugar, I'm a primatologist." Don't worry, though, not long after during a full moon, she and Walsh are trading quips prompting Walsh to make ape sounds to woo her. Jeez, Hugh Grant and Robin Wright reportedly turned down these roles? Fools.
Linney, asked why she is trekking to Africa, says with a straight face, "To find … something I lost." What she's really going for is to look for dead explorers (one of them being Bruce Campbell, whom she calls, "My fiancé … my former fiancé!") and while she's at it, to check out that diamond mine coveted by her money-mad boss (Joe Don Baker, in mad-dog, vein-popping mode). On the ground, the cast meets their guide Ernie Hudson, livening things up with an hilarious, spoofy upper-crust Errol Flynn Brit accent to spout witticisms like, "I'm your Great White Hunter – though I happen to be black." Then, there's tribal military revolutionary leader Delroy Lindo, who commands the temporarily detained Linney, Curry and Hudson to enjoy some hotel coffee and cake ("Have some!" he bellows), before he suddenly screams at Currey, "Stop eating my sesame cake!"
The movie gets even daffier, if possible, when the team members brave poisonous snakes, an attack on their boat by angry hippos and other plot developments straight out of the Disneyland Jungle Cruise to finally uncover the lost city – which must have been located in deepest, darkest Paramount studios, it looks so Styrofoam-y. The ruined temple is guarded by a rare tribe of highly intelligent savage killer apes (well, poor, unsung heroes in costumes, anyway), who arouse cheers when they merrily decimate non-essential cast members (like perpetually whining primatologist Grant Heslov, who's now a first-class writer and producer) while Walsh yelps, "Oh, no! The bad apes have the crystal lasers!" A hilarious volcanic eruption worthy of a '60s Irwin Allen disaster adventure movie is just icing on the cake after some of the worst acting, most laughable dialogue and silliest special effects ever committed to celluloid. If you're up for seeing some talented people sent up river, put Congo on your movie itinerary, pronto.
Movies.com, the ultimate source for everything movies, is your destination for new movie trailers, reviews, photos, times, tickets + more! Stay in the know with the latest movie news and cast interviews at Movies.com.
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Paul Banks - Banks (Album Stream)
Thoughts? Marks out of 10? http://drownedinsound.com/news/4145601-stream--interpols-paul-banks-new-album-banks
Really enjoying this.
Only 3 times through but shaping up as a solid 8... there are a few unexpected things in here that I think I'll enjoy the more times I listen
Listening now for the 1st time
I like it. Very Interpolly (as opposed to Julian Pelenti).
8/10 at the 1/2 mark.
pretty good so far
3 songs in but...


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Late-night grub
We asked some of the city's most prominent night owls to name their favorite after-hours eats. Here are their go-to joints.
Mon Jan 9 2012
Photograph: Paul Wagtouicz
Kang Suh
Eugene Cho
Occupation: Cofounder of disco orchestra Escort
Picks: "If it's after the after-party and you need a proper meal, go to Blue Ribbon (97 Sullivan St between Prince and Spring Sts, 212-274-0404; daily 4pm--4am). Where else can you get bone marrow ($16.75) and a perfect medium-rare New York strip ($36) at 3am?"
Bastard Keith
Occupation: Burlesque performer
Picks: "Stanton Social (99 Stanton St between Ludlow and Orchard Sts, 212-995-0099; Mon--Fri 5pm--1am; Sat 11:30am--4pm, 5pm--1am; Sun 11:30am--4pm, 5--11pm) is a ridiculously satisfying bite after a long evening's entertaining. Great service, late hours and a diverse menu. Nothing is less than excellent, but, oh, the beef Wellington ($22). It's basically 10,000 gravied, succulent happy thoughts wrapped in a sex pastry, and the best thing on any menu anywhere."
Andrew Carmellini
Occupation: Chef-owner, the Dutch and Locanda Verde
Picks: "For me, it's got to be Gahm Mi Oak (43 W 32nd St between Fifth Ave and Broadway, 212-695-4113; daily 24hrs) in midtown for some oxtail soup ($13.95). Can't beat it late at night."
Photograph: Stereo Vision Photography
Boo Boo Darlin'
Occupation: Burlesque dancer
Picks: "After a night of dancing, one of my favorite places to go is Oasis (161 North 7th St between Bedford and Driggs Aves, Williamsburg, Brooklyn; 718-218-7607; daily noon--3am) for their $3 falafel sandwiches. For a place with a little more ambience, I love Henry Public (329 Henry St between Atlantic Ave and Pacific St, Cobble Hill, Brooklyn; 718-852-8630; Mon--Thu 5pm--2am, Fri 5pm--4am, Sat 11am--4am, Sun 11am--2am). They have this delicious mac and cheese ($14) served in a small cast-iron skillet, with ample amounts of cheese and an egg baked in the center. [I get it with] a side of brussels sprouts ($8) and one of their signature cocktails—I adore the Kings County Sour ($11)."
Andrew Zimmern
Occupation: Travel Channel host, Bizarre Foods America
Picks: "Late-night food means big flavors and bold, fresh textures—most often I turn to Kang Suh (1250 Broadway between 31st and 32nd Sts, 212-564-6845; daily 24hrs) in Koreatown. It's been around for 30 years, the barbecue and banchan are very good, the noodles and soups are well made, and if you skip the first-floor sushi bar and head upstairs, you and your pals can stuff yourselves silly on bulgogi ($24.99) until dawn comes up."
Binn and Genc Jakupi
Occupation: Nightlife vets; 1Oak, the Box, Miss Lily's
Picks: "One of our favorite late-night spots is Mott Corner (58 Kenmare St between Mott and Mulberry Sts, 212-431-1192; daily 24hrs). Late at night or early in the morning we stop in for the basics: eggs ($3 for two) sunny-side up with Tabasco or a classic BLT ($4). Best deli in town."
Photograph: Kyle Dean Reinford
Occupation: Rapper
Picks: "After a night in the studio, I'll go to Bubby's (120 Hudson St at North Moore St, 212-219-0666; daily 24hrs [closed Mon 11pm--Tue 7am]) in Tribeca to get a quick bite. I like the location a lot because it's really low-key and they have great food. The late-night menu is like homemade diner food—the nachos ($9) are great, you can order breakfast, and they have fresh pie, which is actually pretty amazing. Their lemonade ($6) is also homemade and one of the best [versions] in the city."
Derek Ferguson
Occupation: Co-owner, Santos Party House
Picks: "Maybe this is cheating because it's right around the corner from my crib, but when I want to unwind, Bar Veloce (175 Second Ave between 11th and 12th Sts, 212-260-3200; daily 8am--3am) is my spot. Excellent wine and delectable little snacks, like the prosciutto di Parma panini ($12), that hit the spot when you want to nosh but don't want to eat too much before going to bed. The staff's crisp attire and attention to detail seal the deal."
Photograph: Allison Michael Orenstein
Molly Pope
Occupation: Chanteuse about town
Picks: "I don't like to take chances at 4am on an empty stomach after singing and hosting my face off for four hours, so I stick with a classic two slices of pepperoni pizza ($2.50) and a large soda ($2) from Karavas Pizza 'N' Pita (108 Seventh Ave South at Christopher St, 212-807-0705; Daily 11am--4am). Low-key, greasy food, open [late]: the perfect hangover-prevention kit."
Joaqun Simo
Occupation: Bartender, Death & Company
Picks: "My late-night local is South Brooklyn Pizza (122 First Ave between St. Marks Pl and E 7th St, 212-533-2879; daily 11am--5am). I get a slice or two of their superb Margherita ($4) to soak up the damage [from drinking] at Bua."


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Contact me
If you have any comments or suggestions about this web site, or would like to contact me regarding Paterson history, please email me at:
Many people help with information, comments and suggestions about Paterson's history. I would like to thank Cameron Archer, David Brouwer, Jack Sullivan, Val Anderson and members of the Paterson Historical Society for their continuing assistance and support.
Brian Walsh


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by Cole Manhattan
(Boston, Ma)
I have a severe fear of Vomit. When people cough I freak out thinking they might get sick or get me sick. WHen i see little kids i think they're going to throw up, It's insane I now have bad OCD and Anxiety attacks from this terrible phobia. You'd think The average Kid should be out on saturdays with they're friends, but no. Im 14 And i never leave my house. I live in a downtown region, and everyone here parties! except for me.
Every time i take the bus, i see kids i freak out and sit in the back alone. I count how many kids are they're and if they look ill at all. Same as teenagers at night. I do not go near intoxicated people. Thats the OCD part. That i count and if there is more then 20 kids i must get off, because i feel like it will be a cycle of vomit, one kid vomits then the next then the next. I also don't like it when people who are sick sit near the exit because, then I'll be trapped.
I went on a field trip with my school where kids started throwing up, i freaked out and had an anxiety attack. And all the teachers just laughed. And i don't blame them, its a stupid phobia, its a daily life cycle. But for me its my life. I can't even live my own dreams with it. I can't go to a regular university because of the campus. I have to live at home. Its sad how one phobia can lead to OCD that leads to anxiety attacks, and then leads to Trapped in your own home.
for anyone suffering this disease GET HELP. before its s late. It's too late for me.
Live your dreams
Join in and write your own page! It's easy to do. How? Simply click here to return to top phobia.


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Sanbona Wildlife Reserve
It was only recently that I had a game experience that restored my faith in game reserves. That was my visit to Sanbona Wildlife Reserve. What sets Sanbona apart from other reserves apart from its size, is that there is no intervention. The animals live the way they are meant to. It's the real deal.


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On tonight's show, the phone lines were open to get your take on the immigration situation in the south. Explanation of society of puppet governments came into existence in the second segment. Finishing out the show with a news run down and the current state of tyranny. Everyone tune in every Wednesday 9:30pm-11:30pm EST!
Are you a slave? Is the USA a corporation? Is the USA a plantation? Do you sometimes feel like a cow being led to slaughter? How can there be debt and no Money? Is Fort Knox Empty? What happened on 911? Give up on the political process? Look into Anarchism Yet? Many questions, many answers. Give our show a try. We will break News in the Freedom Underground and share truth as soon as we can. We are a group of Admin Heavy Hitters in the Activism Scene.
Click for More about The Big Plantation
LIVE: Sundays 7:00pm-9:00pm Eastern
Podcast: Play in new window


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Listen to this article
Architect Gordon Carey is spending a sunny afternoon in the garden of his Umbrian farmhouse, sipping a chilled glass of Sauvignon. It seems idyllic, but there is a problem: "It's finished now," he says, "so it's about time we moved on."
Carey, 62, and his wife, Tilly, are self-confessed serial restorers who have been buying and patching up old properties for 30 years. Once they feel settled, they want to start all over again, making a profit on every restoration – or so they hope.
Their first project was a derelict Georgian townhouse in Leeds, which they bought in 1983 at auction for £11,000 and spent the next three years restoring. "We kept the shell and all the period details that we could, and then we went through putting in a new kitchen and bathrooms, all in harmony with what was there originally," says Carey. The couple sold the house in 1995 for £200,000.
The Careys have restored six properties to date, their latest being Casa Montecastelli, a 500-year-old farmhouse half an hour's drive from Perugia, central Italy, which cost them €700,000 in 2002. "When we bought it the barn was completely derelict," he says. "The roof and the walls were falling in. Somewhere along the line the main house had been turned into five separate apartments, so we had to take all that out and turn it back into a home." Now it is finished, the couple are marketing the 10-bedroom property, which comes with 10 acres of land, through Knight Frank for €1.95m. "When it's sold we will cover our costs on this one, but we do it for the love of doing it. We want to create a home, and then when it's done we move on and do it again," says Carey.
Dawn Carritt, director at Jackson Stops & Staff and a specialist in UK listed buildings for more than 20 years, believes there is a certain type of person who is drawn to restoration projects. "They're people who have a passion for old buildings and want to see them returned to their former glory," she says. "They're not people looking to turn a quick profit." In fact, Carritt thinks there is only one type of restoration with any serious moneymaking potential, the so-called "enabling development". "This is where the developer has permission to add new-build components or convert outbuildings into revenue-raising flats or houses," she says.
A serial restorer who works in this way is Karl O'Hanlon, from Dublin. He bought his first restoration project in 2008 – a crumbling château and winery in the Languedoc region of France – and transformed it into Les Carrasses, a €12m development of 28 residential units, a restaurant and winery. "When we bought the place it was almost entirely derelict," he says. "The winery hadn't been used for 20 years." The restoration process was not easy and, at the height of the 2008 financial crises, he wondered if he would lose the shirt off his back.
Still, thanks to funding from a local bank, Les Carrasses opened in 2011. Bitten by the restoration bug, O'Hanlon was ready straight away to do it all again, this time on an even bigger scale, with more units and a bigger chance of coming unstuck.
"We bought the second place the same year Les Carrasses opened," he says. "The new château dates back to 1896 and needed some major restoration work. We had to redo all the electrics, the plumbing, the sewage, walls, floors – everything."
Called St Pierre de Serjac, the €20m development in Languedoc will consist of 36 residential units, ranging from €384,000 for a studio to €1.1m for a three-bedroom apartment. The units went on sale at the end of May through Abercrombie & Kent and 28 have been sold so far.
O'Hanlon, 41, who used to work for management consultancy BCG, thinks he was first drawn to the restoration game by his love of old architecture, but his business training helped him turn this interest into a way of making money. "Finding sources of defensible competitive advantage was drilled into us at BCG," he says, "and I think we [Domaine & Demeure, the restoration and estate management company O'Hanlon founded in 2008] have that. Our developments occupy a middle ground. We have more scale than the private investors who buy two or three properties, but we're more flexible and personal than the big boys, Pierre et Vacances or Club Med. So we saw that gap in the market and went for it."
Restoration projects do not always run smoothly. Company director Philippa Farrow, 51, had developed two Oxford properties before coming unstuck on the restoration of an 18th-century farmhouse in Umbria.
The Financial Times first caught up with Farrow in 2004, at the height of her misfortune. "I bought the place in 2001, but by then costs were spiralling out of control and I was in danger of losing the family home in Oxford," she says. Farrow had no other option than to put the house on the market in 2007 for €3m, but even that did not go according to plan: she discovered that crucial paperwork concerning the restoration work was missing.
Still in love with that part of Umbria, in 2008 Farrow struck a deal with a local landowner: she would rent an old derelict house about a mile from her old farmhouse, and renovate the inside while the landowner took care of the exterior. "When I first started the place was falling apart. It was being lived in by about 40 cats and 50 dogs," she says. After two years the property was finished but, although she was pleased with the new house, Farrow would still drive past her old farmhouse, wondering what was going on inside. "I never saw any cars going in or out or anything, so one day I called up the person I sold it to."
Farrow struck another deal: she would rent her old farmhouse on the condition she could redesign the interior. She has since returned it to the high-end rustic style she favoured when she first restored the building. "We have come full circle, but I've definitely learnt a great deal since then," she says. Today, Farrow runs holiday rentals from the property, San Martino, which can sleep up to 22.
Building and surveying costs are not the only pitfalls for would-be property restorers. A major concern with any restoration job is building regulations. Different rules across the globe mean it is vital that a potential restorer is well-versed on local regulations before embarking on a project.
According to Carritt, of Jackson Stops & Staff, this is especially true in the UK. "If you're restoring a listed property and changing its use – perhaps turning an old house into flats – then not only do you have to follow heritage regulations, but you also might be required to follow new building regulations too; even if they are contradictory," she says.
Carritt explains that a planning authority might insist a finished property has fire doors and double glazing, while English Heritage might completely forbid it. Her advice? "Always go with the heritage regulations and get them to consult and agree with the planners – that way you're not piggy in the middle."
Kate Ashton, 50, and her husband, Charlie, had to jump through a series of planning hoops to satisfy the restoration regulations on their country house in Essex. "When we bought Rivenhall Place in 2000 we were told it was Grade II-listed, but after a few months we discovered it was actually Grade II*-listed, which, it turns out, is a whole different ballgame. We had all sorts of Georgian preservation societies getting involved then," she says.
The bolstered regulations meant the Ashtons could not replace the glass in some windows, while specially cast bricks and a certain type of mortar had to be used in some place in keeping with the original structure. This was despite the fact that when they bought the property it was in serious need of repair, with 4ft of water in the basement. "Still," she says, "if you are going to take on the restoration of a lovely old house like this, you have to be prepared to do it properly."
Playing by the rules seems to have paid off. Having bought Rivenhall Place for about £1.5m just over 12 years ago and spending in the region of £2m on the house and grounds, the couple are now marketing it for £5.5m, through Jackson Stops & Staff.
So, what is next for the Ashtons? "We'd love to restore another house, just perhaps not on this scale." she says. "Not right away, anyway."
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Most emergency managers maintain detailed inventories of critical infrastructure, their vulnerabilities, state of repair, and hotspots around town that are more easily impacted (i.e. the roads that always flood or ice over), so why is there not the same amount of information available about the residents of a community? As it approached and ultimately made landfall in the northeastern United States in late October, Hurricane Sandy demonstrated the importance of emergency management officials' awareness of who resides and works in their communities, where they are located, and what kind of assistance they will require should a disaster strike. Some of this information is available; however, it is typically collected by various entities, managed in different systems, and not rapidly accessible when it matters most.
There is much concern in certain populations, and rightfully so, about participating in a special needs or disability registry. Many individuals who are differently-abled, for example those who are deaf or hard of hearing, do not feel inclined to participate in such a system that labels them or singles them out. Two weeks ago, I had the opportunity to take a full-day course offered by the Boston Public Health Commission called Emergency Planning for the Diverse Needs of Communities. This outstanding program was designed to familiarize participants with FEMA's concept of Whole Community Preparedness, in particular, understanding the needs of and preparing for vulnerable populations. One of the main objectives of the course was to broaden everyone's thinking about what exactly it means for a member of the community to be "vulnerable" and in need of special consideration by emergency managers. We went around the room rattling off different characteristics that we felt would put someone into that category. The activity began with the more traditional definitions – those with mobility limitations and developmental disabilities – and quickly progressed to others not traditionally considered. By the end, the list included the following:
- Those with limited proficiency in speaking, reading, or understanding the English language
- Children
- The elderly
- Deaf or Hard of Hearing
- Visual impairments
- Individuals with medical conditions (particularly those requiring home healthcare, regular outpatient treatment, such as dialysis, or electrically-powered medical devices)
- Institutionalized individuals (assisted living, nursing homes, the incarcerated)
- Caregivers (single parents, medical professionals, social workers, first responders)
- Economically disadvantaged
- Those without access to transportation
- Pet owners
There were other segments of the population mentioned, but even just the above list demonstrates that our at-risk populations include far more than we once planned for. In fact, in Boston, City officials have estimated that anywhere between 39.7% and 46.9% fall into the categories of vulnerable or requiring assistance. Perhaps complicating preparedness efforts even further is the fact that many individuals are vulnerable for multiple reasons – the elderly woman who is the primary caregiver for a grandchild, the child with a significant medical condition (and his parents), etc. The complexity surrounding the makeup and needs of our communities, as well as the shortcomings in recent disasters of responding to those with certain needs, have been large drivers behind FEMA's focus on the concept of Whole Community Preparedness. That is, the effort to develop emergency operations plans around all of the needs of the community, rather than the relatively small portion of the population that is self-sufficient.
In speaking with emergency management and public health officials, as well as advocacy groups and ADA coordinators, since joining Rave, I have an appreciation for why there is hesitation for being singled out in a government-maintained registry. However, when you consider the breadth of individual and community issues that emergency managers must be prepared to respond to, it strikes me that if properly deployed and marketed, local or state government could capture this information in such a way that it would not be construed as a registry.
More specifically, if the goal is to maintain up-to-date and detailed information about the residents and commuters of a jurisdiction who could be considered vulnerable (i.e. upwards of 50% in some places), then you are no longer targeting two or three specific populations. In fact, this is why we have had such broad support from advocacy groups and ADA coordinators alike for how we market and collect information in Smart911 and Rave Prepare. Smart911 and Rave Prepare partner jurisdictions target every segment of their population for participation in the programs. Of course they will reach out to the Deaf and Hard of Hearing and Autism communities, but they will also message parents, pet owners, and even the young and healthy. Because everyone can at some point benefit from maintaining an updated Safety Profile in our system, no group is singled out. This is the distinction that allows all members of the community to feel comfortable with sharing their information and, ultimately, providing 9-1-1 call takers, first responders, and emergency managers with the vital information needed to enhance response.
When upwards of 50% of some communities fall into the "vulnerable" category, you are no longer talking about special needs. These are normal needs, not just outliers to be addressed in annex to an emergency operations plan. It is for this reason that we need to shift our thinking from maintaining information in a registry to that of a whole community assessment that helps us understand the composition of those we are responsible for serving and protecting.
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Cory Greenwood LB FA 5 years ago
Lions waived LB Cory Greenwood.
Greenwood was claimed off waivers from the Chiefs in May. Greenwood appeared in all 16 games each of the past three seasons, and could get a look elsewhere as a special teamer.
Cory Greenwood LB FA 6 years ago
Lions claimed LB Cory Greenwood and G Derek Hardman off waivers from the Chiefs and Bucs, respectively.
Detroit is picking up other clubs' unwanted pieces as it attempts to fill out its 90-man offseason roster. Both of these guys will be cut by the fall.
Cory Greenwood LB FA 6 years ago
Chiefs waived LB Cory Greenwood, QB Alex Tanney, and OL Bryan Mattison.
Greenwood appeared in all 48 games since signing as an undrafted free agent prior to 2010, making 29 tackles as a pure special teams player. Tanney was one of five quarterbacks on the roster.
Cory Greenwood LB FA 7 years ago
The Chiefs have reportedly agreed to a four-year, $2.75 million extension with LB Cory Greenwood.
Scheduled to be an exclusive rights free agent, Greenwood led Chiefs special teamers with 12 tackles in 2011. Undrafted out of Concordia University in Canada, Greenwood has been a core special teamer since signing in Kansas City two years ago.


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The 4 star Newpark Hotel rests on the edge of medieval Kilkenny City, a cultural gem of festivals and historical sites.
On over 40 acres of parkland, offering luxurious accommodation, a Health Club & Spa and fun filled kids' activities, this family-friendly hotel is the ideal base for exploring Kilkenny.
With elegant banqueting suites, suitable for a large or intimate Kilkenny wedding and spacious conference facilities, our dedicated team will ensure all your needs are met whether you are here for business or pleasure.
Celebrate Christmas at NewparkBook your Christmas stay with us, 2,3 & 4 Night Inclusive Packages available with arrival 23rd or 24th December 2018
Midweek OffersTake a well deserved midweek break in this central Kilkenny Hotel. Relax & unwind in our Escape Spa, Indulge in Afternoon Tea in our Luxurious Lobby, Savour our culinary delights in Scott's Bistro


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PARKLAND - Pacific Lutheran put it all together against visiting Whitworth on Saturday afternoon, rolling up 12-0 and 14-0 victories in a pair of five-inning Northwest Conference softball games played at the PLU field.
The Lutes had a total of 26 runs and 26 hits in eight innings of offense and allowed no runs and a total of nine hits in 10 innings of defense to improve to 8-4 overall and 6-0 in the conference. Sami Parr had four hits on the day for the Pirates, who are now 2-10 overall and 0-6 in the NWC.
First Game - PLU 12, Whitworth 0 (5 innings)
Stacey Hagensen improved her season record to 4-3 by allowing only five hits while striking out eight and not walking a batter in going the five-inning distance.
She got plenty of offensive support from her teammates as Katie Lowery, Glenelle Nitta and Lindsey Matsunaga all clubbed home runs.
PLU scored five times with two outs in the first inning. Amanda Goings led off with a double and Haley Harshaw was hit by a pitch to lead off the frame, and both moved up on a double steal. With two outs, Amanda Hall drilled a double to drive in Goings and Harshaw, and Lowery followed with a majestic home run to straightaway left field. Nitta followed with a home run over the centerfield fence, and just like that the Lutes were on top 5-0.
Pacific Lutheran added three runs on just one hit in the third inning, loading the bases when Hall and Nitta were hit by pitches sandwiched around Lowery's single. All of the runners moved up a base on a wild pitch, accounting for the first run, and after a walk, pinch hitter Ami Gran was hit in the helmet to bring in the second run. Another pinch hitter, Katie Bologna, drew a bases-loaded walk for the final run of the frame.
The Lutes put the game on ice with four runs in the bottom of the fourth, highlighted by Matsunaga's third homer of the campaign, a three-run shot to left field. Montessa Califano followed with a triple to centerfield, and she scored on a ground out by Amanda Goings.
Whitworth's best chance to score came in the fifth when Jessica Ross led off with a single and later advanced to third on Sami Parr's infield base hit, but Hagensen kept the shutout by fanning Hanna Boyd to end the game.
PLU collected 11 hits in the game, including two apiece from the No. 6 through No. 9 hitters in the lineup - Lowery, Nitta, Matsunaga and Califano. Matsunaga led the way with three RBI, and both Hall and Lowery drove in two.
Parr led Whitworth's five-hit offense with a pair of singles. Pirates starting pitcher Riley Fritz took the loss after allowing five earned runs on six hits in one inning of work.
Game Two - PLU 14, Whitworth 0 (5 innings)
Karen Hatlen improved to 4-0, allowing only four hits and one walk while striking out seven in her five-inning complete game. She also played a big part of a 15-hit attack, finishing 3-for-4 with four runs batted in an two runs scored.
Hall, hitting behind Hatlen in the lineup, was 3-for-3 with a pair of runs batted in, and for the second straight game Matsunaga clubbed a three-run homer while going 2-for-2 with four total RBI.
Pacific Lutheran scored three runs on three hits and two Whitworth errors in the opening inning, with Hatlen, Hall and Matsunaga all collecting RBI singles in the frame.
The Lutes scored six runs on five hits in the second. Hatlen had a two-run single and Matsunaga ripped her three-run line drive homer over the left field fence to highlight the outburst. The sophomore shortstop from Kaneohe, Hawaii, finished the day 4-for-4 with two homers, seven RBI and two runs scored.
PLU added three more in the third and two in the fourth. In the third inning, Hagensen and Hall sandwiched run-scoring doubles around a RBI infield single by Hatlen. The fourth-inning runs came as a result of leadoff hits by Lowery and Shelby Hasse, who both scored on a throwing error.
Parr had her second consecutive two-hit game for the Pirates, who left a runner in scoring position in each of the first three innings. Ross was the losing pitcher, allowing eight runs, seven earned, on seven hits in 1 1/13 innings.
The teams complete their four-game NWC series with a Sunday doubleheader. First pitch is scheduled for noon.


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No. 68 and 69
John and Patrick Cahill died within seventeen days of each other, on the Feb 3rd and Feb 29th respectively, in 1818. John was twenty nine and Patrick was thirty one. They have matching headstones
No. 39
In January 1841 John Foley of Ballinamone buried his son and his mother within fourteen days of each other, the 2nd and 16th respectively. His son Thomas was thirty and his mother Mary was eighty years of age
No. 72c
The youngest person commemorated is Walter Curran, of Ballymacart who died at the age of nine months
No. 5
The oldest recorded age in the nineteenth century is 95. This was Nicholas Veale of Hackettstown who died in 1844
No. 14
John Whelan of Ballyvallona lived to the age of 90. He died in 1905. This is the oldest recorded age in the twentieth century
No. 39
May Foley of Ballynamone was the longest living woman recorded in the nineteenth century. She lived to the age of 80 and was buried in 1841
No. 57
Ellen Hourigan of Ballinaharde lived to the age of 86, and is the oldest listed woman in the twentieth century. She was buried in 1965.
No. 55
James Troy died in 1761 aged 71 years. This indicates that he was born in 1690. This is the earliest recorded date
No. 73
Richard Ryan of Ballintlea who died in 1813, aged 62 is reputed to have translated the poems of Tadhg Gaelach Ó Suilleabháin
Curreen is the most common surname, most likely an anglicised spelling of the Irish Cuirrín
The surname Fowlow is also most likey an Anglicisation of the Irish Foghlú
The earliest recorded death is in 1740 (No. 48)
The most recent death is 1998 (No. 76)
Men's Names
John is the most common name, listed 18 times
Patrick and James are both listed 12 times
Thomas is listed 9 times
Michael is listed 7 times
William is listed 5 times
David is listed 4 times
Maurice and Walter are both listed 3 times
Richard, Edmund, Bartholomew, Nicholas and Jeremiah are all listed twice
Martin, Darby, Jerry, Garrett, Cornelius, Patrick Joseph, John J., and Henry Thomas are all listed once.
Women's Names
Margaret and Mary are each listed 11 times
Bridget is listed 6 times
Ellen, Catherine, Johanna are all listed 4 times
There are 2 Julia's listed
Anne, Annie, Kate, Nell, Mary Anne, May, Joan, Honora , and Elizabeth appear once
Died in
There are a number of souls commemorated who are not actually interred in the graveyard
No. 33 – Patrick Merrick died in
No. 42 – James Peters died in
No. 42 – Jerry Peters died in
No. 42 – Patrick Peters died in
No. 65 – Anne Fitzgerald, died in


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Hotel Amendola Fiera, the solution just for you
A good value hotel, a strategical position in the city of Milano; located in one of the most beautiful district, quite and green area of Milan, 20 minuts walk away from Meazza Stadium and 10 from Fieramilanocity, just behind Istituto Auxiologico San Luca and very close to "Il Sole 24 ore" headoffice.
The nice home environment, fresh and friendly and the reachable position for public transportation belong to the strength of the hotel.
By the underground you can reach the down town, for 10 min.
The quite, fresh and friendly home environment, the good value: those are some of our strength


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The Set includes many types of bridge building levels, in varying degrees of difficulty from simple to complex, and with a tutorial section to get you started. A Level Editor is also included, so you can create your own levels and trade them with others.
"A truly innovative game idea, with testing in real-life scenarios," comments Jay Moore, Evangelist for GarageGames. "BCS is one of those stealth games that sneaks up on you. Just when you think you have mastered the art of bridge building, you find yourself caught up in endless hours of fun as you keep running the train onto your perfect bridge creation just to watch it plunge into the river."
"Its has been great to see what the players have done with BCS", explains Josiah Pisciotta, Co-Founder of Chronic Logic LLC. "They have really taken this game and ran with it, creating contests, and record web pages. People are still coming up with solutions that amaze me. Its wonderful to see people creating bridges beyond the possibilities that we ever envisioned."
Bridge Construction Set demo version with tutorial and five levels is available for Windows and Linux. The full version is now on sale for $19.95 at www.garagegames.com.


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if u wont to know how to get a couple of freebees go to your parents or grandparents and they will give you something then exit and go back in do this as many times as u like but you can only do it a few times with da grandparents because they will say "dont worry about me i'll be fine" and then she wont give you any more gifts so repeat the glich with your parents!!!
PM me if you've got any more questions or gliches.
Edited by Spikey9, 20 October 2006 - 07:35 PM.


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Raccoons are among nature's most clever animals which have superlative survival skills. Several things about a house can be appealing to a raccoon. Harsh weather, breeding, and pure fascination can all be definite influences for raccoons to take refuge or trespass onto your yard. Continue reading to find out some reasons why you may be spotting raccoons more frequently on your property from
Critter Control Cost, and the way to get rid of them for good.
Raccoons are motivated by food; just like any other wild animal. When homeowner's leave food resources out or in their garage, raccoons are certain to sniff it out. They are great at hunting down foods, especially easy ones. Edibles such as pet food, garden fruits/veggies, bird feed, and even filthy grills can all be desired snacks for raccoons and other wildlife. If you have one of these items on your property, it may be the cause of your late-night visitors.
Outdoor pets, such as cats and dogs, should be fed indoors or in garages. This prevents the need to leave pet dishes filled with food, outdoors. Raccoons love dog and cat food; it's yummy and provides nutrition and protein. When feeding a pet inside is not an option, consider bringing the food dishes in at nighttime when raccoons are most active, then put them back in the morning. On the same topic, gardens should also be secured to prohibit entrance by raccoons, rabbits, and other garden nuisances.
Trash and garbage cans are another potential food source for raccoons. Lots of people would rather take their garbage out at night, prior to the morning of pickup. Although this saves a couple of minutes in an otherwise busy afternoon, this can be a main attraction for nocturnal wildlife. They are easily able to open up garbage lids and rummage through leftovers, litter, waste, along with other compost. This not only leaves a mess for homeowner's to wash up in the wee hours of the morning, but it creates a rift among fellow neighbors who dislike the unsightly garbage spread throughout their curb.
Open Access
Cracks and crevices in rooftops are easy entry points for raccoons. They can gain access to attics, garages, crawl spaces, and outside sheds and storage spaces. This easy access is a wide open invitation for raccoons to come inside. As mentioned earlier, harsh weather conditions and mating seasons promote raccoons to look for shelter in dens, or in residential properties.
Raccoons will remember where dependable shelter and food sources are, and so to keep raccoons out of your yard, you need to figure out what is attracting them in the first place. These areas above are a fantastic place to start. Next, contact a local wildlife removal company to securely and Humanely catch and relocate raccoons out of your premises.


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News from the follow-up trip on the frontier of Badezu deep in the Buluyema Forest of Liberia, West Africa…
After God blessed our team (Liberians, Austrians, Americans, and Belarusians) with the opportunity to fly into Badezu by chopper on a one day trip, Pastor Willie Johnson was able to lead a team of 5 back on the long hike to the Buluyema Forest for a week long follow-up ministry there. We received a call upon Pastor Willie's return that the trip was blessed and productive. The team was able to visit homes from village to village and host daily morning devotions and daily evening worship services. During their time there, 28 people prayed to receive Christ and the Sunday morning worship service had 68 adults in attendance from Badezu alone. There is one brother in position to continue some discipleship and teaching while he is in Buluyema.
Work on a water-well for the community has been started, and also eager hands are joining together to make blocks to be used in the construction of a building for worship and guest lodging! Please continue to praise God for His heart that all might know Him and belong to Him and pray for the discipleship and growth and encouragement for our new brothers and sisters!
After our fruitful visit to Guinea just about a week ago, Pastor Harris (our pastor in Kpassagizia) has been able to cross the border for Bible study in the biggest town across the Guinea/Liberia border! The few believers there have planned with Pastor Harris to have a weekly Bible study on Wednesday evenings in their town. The Gospel attack across the border that we have been praying about for so long now is really coming to life—please pray for continued laborers in the field…the harvest is ripe indeed!


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Morphological traits and 3 molecular markers techniques: start codon targeted (SCoT), inter-simple sequence repeat (ISSR) and directly amplified minisatellite DNA (DAMD) markers were compared for fingerprinting of 40 landraces chickpea genotypes gathered from different physical locations of north-west of Iran. SCOT, DAMD and ISSR markers was fairly 53-86-1 supplier the same in fingerprinting of genotypes but SCOT and DAMD evaluation are far better in fingerprinting of chickpea genotypes. To your knowledge, this is actually the initial detailed report of the comparison of functionality among two targeted DNA area molecular markers (SCoT and DAMD) as well as the ISSR technique on a couple of examples of chickpea. General, our outcomes indicate that SCOT, DAMD and ISSR fingerprinting could possibly be utilized to detect polymorphism for genotypes of chickpea. L.) (truck der Maesen 1987; Talebi et al. 2008a). India and Ethiopia have already been proposed as supplementary centers of variety of cultivated chickpea (Harlan 1992). Nevertheless, Zeven Mouse monoclonal to Mcherry Tag. mCherry is an engineered derivative of one of a family of proteins originally isolated from Cnidarians,jelly fish,sea anemones and corals). The mCherry protein was derived ruom DsRed,ared fluorescent protein from socalled disc corals of the genus Discosoma. and de Moist (1982) recommended that chickpea provides different supplementary centers of variety situated in at least four locations; the Near East Region (composed of the Fertile Crescent), Hindustani Region (simply the current India and East Pakistan), Central Asian Region (with Afghanistan, American Pakistan, Iran as well as the south from the former USSR) as well as the Mediterranean Region (including Lebanon and Palestine). Evaluation of the level of hereditary variability within chickpea is normally fundamental and very important to chickpea mating and conservation of hereditary resources, and it is useful as an over-all guide in the 53-86-1 supplier decision of parents for mating hybrids (Talebi et al. 2008b). Today it really is realized that the usage of genetically different types is an efficient strategy to be able to reduced hereditary vulnerability (Fatehi et al. 2011). Based on their physical locations, landraces had particular hereditary background you can use in hereditary research plan (Harlan 1975). Furthermore, landraces are essential hereditary assets that improve gene private pools of contemporary cultivars by presenting brand-new alleles (Nevo and Payne 1987). Requirements for the estimation from the hereditary diversity could be different, such as morphological features, biochemical or molecular markers (Carvalho 2004; de Vicente et al. 2005). Nevertheless, it really is generally thought that the usage of molecular markers is normally more dependable and repeatable when compared with characterization predicated on morphological individuals (Carvalho 2004). Several DNA structured markers are actually designed for the effective quantification of hereditary variation in place species. Collectively, methods such as for example AFLP, RAPD and ISSR, have been referred to as arbitrarily amplified prominent (AAD) markers (Wolfe and 53-86-1 supplier Liston 1998) and so are increasingly employed for diagnostic genomic fingerprinting, hereditary and qualitative characteristic loci (QTL) mapping and people hereditary research in chickpea (Iruela et al. 2002; Talebi et al. 2008a,b; Mahmood et al. 2011). Recently, the microsatellite sequences have already been utilized as primers in polymerase string reaction, where do it again motifs are anchored either at 5 or 3 end with one or few particular nucleotides and amplify the sequences between your two microsatellite loci known as inter basic sequence do it again (ISSR) markers. Furthermore, ISSRs could be targeted towards particular sequences, that are reported to become loaded in the genome and will overcome the specialized complications of RFLP and RAPD (Rajesh et al. 2002). Lately, many new choice and appealing marker techniques have already been developed based on the rapid development of genomic analysis (Gupta and Rustgi 2004). With initiating a development away from arbitrary DNA markers towards gene-targeted markers, a book marker system known as Begin codon targeted (SCoT) (Collard and Mackill 2009) originated predicated on the brief conserved area flanking the ATG begin codon in place genes. SCoT markers are reproducible generally, which is recommended that primer annealing and duration heat range aren't the only real factors determining reproducibility. Minisatellite DNAs are repeated parts of genomes tandemly, a lot of which 53-86-1 supplier present high degrees of duration differences because of variations in the amount of do it again systems (Jeffreys et al. 1985). This system was reported by Heath et al first. (1993) and referred to as aimed amplification of minisatellite-region DNA (DAMD). It really is speculated that minisatellites as well as the DNA sequences flanking them.
Telomere maintenance is an important genetic mechanism controlling cellular proliferation. explored
Telomere maintenance is an important genetic mechanism controlling cellular proliferation. explored evidence for the ALT pathway in chicken cell lines by studying nontransformed immortalized cell lines (DF-1 and OU2) and comparing them to a normal (mortal) cell collection and a transformed cell collection (DT40). The research consisted of molecular and cellular analyses including profiling of telomeric DNA (array sizing and total content) telomerase activity and expression of genes involved in the telomerase recombination and ALT pathways. In addition an immunofluorescence analysis for an ALT marker i.e. ALT-associated promyelocytic leukemia body (APBs) was conducted. Evidence for ALT was observed in the telomerase-negative immortalized cell lines. Additionally the APB marker was within the other cell systems also. The attributes from the chicken offer an extra vertebrate model for analysis from the ALT pathway. mouse cells [Niida et al. 2000 Chang et al. 2003 but is not reported in various other vertebrates. A combined mix of markers provides proof which the ALT pathway is normally operating to keep telomeres [Pickett and Reddel 2009 The markers of ALT are the lack of telomerase activity in immortalized (or changed) cells (i.e. cell types with unlimited proliferation potential) a heterogeneous terminal telomeric DNA account (i.e. a sophisticated variable size selection of telomere array measures) and existence of nuclei which display ALT-associated promyelocytic leukemia (PML) systems referred to as APBs. Specifically the APBs are believed a definitive marker for ALT [Yeager et al. 1999 These nuclear systems support the PML protein with telomere-associated proteins (TRF1 TRF2) plus DNA fix and recombination proteins (RAD51 RAD52 MRE11 RAD50 NBS1). The existing model shows that the ALT system utilizes telomere homologous recombination to keep and even extend the telomeres [analyzed Mouse monoclonal to Mcherry Tag. mCherry is an engineered derivative of one of a family of proteins originally isolated from Cnidarians,jelly fish,sea anemones and corals). The mCherry protein was derived ruom DsRed,ared fluorescent protein from socalled disc corals of the genus Discosoma. in Cesare and Reddel 2008 Nevertheless an individual definitive assay for the ALT pathway will not can be found and as stated detection would depend on markers proven experimentally to become from the pathway [Cesare and Reddel 2010 A quality feature from the poultry genome is it possesses an extremely heterogeneous telomeric DNA profile [Delany et al. 2000 Rodrigue et al. 2005 O'Hare and Delany 2009 with least in meiotic cells proof is available for high prices of telomeric DNA recombination as proven by the era of book telomere arrays in progeny not really observed in parental genomes [Rodrigue et al. 2005 Oddly enough the immortalized poultry cell series DF-1 maintains an unusually massive amount heterogeneously size telomeric DNA and higher than 3-fold even more total telomeric series content than regular rooster cells [O'Hare and Delany 2009 Further it had been reported by Christman et al. [2005] that telomerase activity had not been detectable in the DF-1 cell series. Predicated on these mixed results it appears plausible which the chicken which stocks many telomere biology features with 3,4-Dehydro Cilostazol individual [Swanberg 3,4-Dehydro Cilostazol and Delany 2006 Swanberg et al. 2010 could also possess the capability to hire ALT being a system to keep telomeres. This analysis investigates the hypothesis that poultry similar to individual possesses an alternative solution system for preserving telomeres particularly ALT. Four cell lines with differing proliferation phenotypes had been examined including 2 immortalized poultry embryo fibroblast cell lines (DF-1 and OU2) a standard (mortal) poultry embryo fibroblast cell collection and a transformed cell collection (DT40). Telomerase activity manifestation of genes associated with the telomerase and ALT pathways including telomere-associated DNA restoration and recombination genes and the presence of an ALT marker (APBs) were investigated. 3,4-Dehydro Cilostazol Evidence for ALT was found in the immortalized lines as they were bad for telomerase activity experienced normal or larger amounts of telomeric DNA having a 3,4-Dehydro Cilostazol heterogeneous profile and exhibited APBs. Interestingly albeit to a lesser extent APBs were also observed in the telomerase-negative mortal cells as well as the telomerase-positive transformed cells. Overall these results suggest the interesting probability that the 2 2 telomere-lengthening pathways i.e. telomerase and recombination-based ALT coexist as redundant.


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I love Fridays at work. No one sits beside me and I can play music at an audible level. I also love the cherry blossoms right now...I love how the branches hang so strained under the weight of the delicious looking blooms. When the wind blows them I am sure they will snap off...but they don't.
I am not chatty these days...not much to say...not to say I ever have anything earth shattering to say but I usually just speak when I feel compelled to and lately I just don't feel compelled. The impending doom of summer – while I love this spring weather – does not please me. As it turns out – despite my best efforts to keep my head above water – after graduation next month and all that goes with that I am not off the hook like I thought....looks like Ayla must get her wisdom teeth out so I may as well just buck up and do that now and it will be over with. It hasn't been particularly pleasant for her as of late with 1 tooth giving her problems so the sooner the better...I do see a little light at the end of the tunnel though....eventually. haha
Logically I know I need to turf my land line telephone but I just can't convince myself to do it...it seems so welfare to not have a home phone...and while I have free LD with my cell phone I hate talking on my cell phone...h.a.t.e...i.t. Perhaps when I upgrade I will feel different but cell phones are not traditionally able to be cradled in such a way that frees both your hands to do dishes etc. Anyone who has ever talked to me on the phone knows I am usually doing dishes while talking b/c then it doesn't seem like work at all. There is always the hands free option I guess...headsets are so goofy though...I dunno...the redundancy is not lost on me...having 2 lines...maybe a cell upgrade and headset of gheyness is the key? Ugh...for as much as I feel like talking on the phone these days the whole debate in my head seems ridiculous.