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ERβ-mediated induction of cystatins results in suppression of TGFβ signaling and inhibition of triple-negative breast cancer metastasis
Edited by J. A. Gustafsson, University of Houston, Houston, TX, and approved August 13, 2018 (received for review May 4, 2018)
This article requires a subscription to view the full text. If you have a subscription you may use the login form below to view the article. Access to this article can also be purchased.
Triple-negative breast cancer (TNBC) is the most aggressive form of breast cancer and patients exhibit high rates of recurrence and mortality in part due to lack of treatment options beyond standard-of-care chemotherapy regimens. In the subset of TNBCs that express estrogen receptor beta (ERβ), ligand-mediated activation of ERβ elicits potent anticancer effects. We report here the elucidation of the ERβ cistrome and transcriptome in TNBC and identify a mechanism whereby ERβ induces cystatin gene expression resulting in inhibition of canonical TGFβ signaling and a blockade of metastatic phenotypes. These findings suggest that ERβ-targeted therapies represent a treatment option for the subset of women with ERβ-expressing TNBC.
Triple-negative breast cancer (TNBC) accounts for a disproportionately high number of deaths due to a lack of targeted therapies and an increased likelihood of distant recurrence. Estrogen receptor beta (ERβ), a well-characterized tumor suppressor, is expressed in 30% of TNBCs, and its expression is associated with improved patient outcomes. We demonstrate that therapeutic activation of ERβ elicits potent anticancer effects in TNBC through the induction of a family of secreted proteins known as the cystatins, which function to inhibit canonical TGFβ signaling and suppress metastatic phenotypes both in vitro and in vivo. These data reveal the involvement of cystatins in suppressing breast cancer progression and highlight the value of ERβ-targeted therapies for the treatment of TNBC patients.
- ↵1To whom correspondence should be addressed. Email: hawse.john{at}mayo.edu.
Author contributions: J.M.R., A.W.N., J.S.C., M.S., J.N.I., M.P.G., and J.R.H. designed research; J.M.R., E.S.B., A.W.N., M.S., V.N., and J.R.H. performed research; J.M.R., E.S.B., A.W.N., I.C., Y.L., M.S., V.J.S., V.N., D.G.M., J.N.I., M.P.G., and J.R.H. analyzed data; and J.M.R., M.S., M.P.G., and J.R.H. wrote the paper.
The authors declare no conflict of interest.
This article is a PNAS Direct Submission.
Data deposition: The ChIP-Seq and microarray data described in this article have been deposited in the Gene Expression Omnibus (GEO) database, https://www.ncbi.nlm.nih.gov/geo (accession nos. GSE108980 and GSE108979).
This article contains supporting information online at www.pnas.org/lookup/suppl/doi:10.1073/pnas.1807751115/-/DCSupplemental.
Published under the PNAS license.
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National Geographic : 1950 Apr
Kew: The Commoners' Royal Garden Around it are the beech, chestnut, and oak woodlands where the birds sing. Kew epitomizes even more than the history of English gardening. Outside London, few spots have seen so much of Britain's storied past as this riverside curve between Kew and Richmond Bridges. Julius Caesar's columns may have forded the Thames here in 54 B. c. In Syon House, closing a vista across the river from Kew, Henry VIII imprisoned Catherine Howard; and from Syon House Lady Jane Grey was carried by barge down to the Tower of London to be for nine days a queen before she died on Mary's scaffold. Where Queen Elizabeth Walked From the near-by Palace of Richmond, Queen Elizabeth liked to walk along the river path by Kew to the lawn marked now by the hollowed stump of a giant elm which was most probably her contemporary. The present "Dutch House," or Kew Palace, in Kew, with the date 1631 showing over the door, then belonged to the estate of Lord Henry Capel, which John Evelyn described as having the "choicest fruit of any plantation in England." Since they bordered his royal parents' residence at Richmond Lodge, Fred erick, Prince of Wales, son of George II, ob tained a lease of the grounds from the Capel family in 1730. The remarkable woman who conceived of Kew as a place where botanically interesting plants would be grown for the sake of the plants was Princess Augusta, Frederick's con sort and mother of George III. In 1759, the same year the British Museum opened, Au gusta started her living collections here on about nine acres of what is now the northeast corner of the Gardens. Augusta's scientific adviser was the third Earl of Bute, who majored in botany while minoring in the relatively less important sub ject of court politics. Her head gardener, William Aiton, had been trained in Chelsea's famed Physic Garden belonging to the Apothe caries' Society. The Reverend Stephen Hales, a founder of experimental physiology, designed the flues in the tanbark-heated greenhouse whose loca tion is marked now by a giant wisteria. Sir William Chambers, her architect, summed up in 1763 the miracle such men had wrought in Augusta's little garden: "The gardens of Kew are not very large. Nor is their situation by any means advan tageous; as it is low, and commands no pros pects. Originally the ground was one con tinued dead flat: the soil was in general barren, and without either wood or water. With so many disadvantages it was not easy to produce anything even tolerable in garden ing: but princely munificence, guided by a director, equally skilled in cultivating the earth, and in the politer arts, overcame all difficulties. What was once a Desart is now an Eden." The impress made by Augusta and her son George III on Kew still shows. Kew Green is almost pure Georgian in tone, from the grassy cricket pitch standing out against the backdrop of St. Anne's Church to the onetime homes of royalty which fringe the green like a sunflower's petals. George III's seven sons made almost a cricket team in themselves, his 13 living chil dren requiring all the houses around the green for shelter. Summering at Kew, Their Majesties rose at 6; and at 8 a procession of royal dukes from the respective houses converged to pay filial respects. Once a week, George and Charlotte, "attended by the whole offspring in pairs," walked around the Gardens "ad miring the works of Nature" and being ad mired in turn by the royal guests. George III's Taste for Science George III's taste for science made Kew while still a private garden, albeit a royal one - a link which bound the tiny island of Britain to naturalists around the world. Advised by Sir Joseph Banks (42 years a president of the Royal Society and circum navigator of the globe on Captain Cook's first voyage*), His Majesty started similar bo tanic gardens in many of the colonies and sent out Kew-trained men to superintend them. Banks made Kew a depot for colonial interchange of plants. And what sowers of seed! There was the Scot Francis Masson, Kew's first plant collector, who explored South Africa and then the Atlantic islands through the French wars. He was taken prisoner twice by French privateers, and finally succumbed to a Canadian winter while still collecting! (Page 495.) And gardener David Nelson, accompanying Cook on his third voyage, and in 1787 sailing on Captain Bligh's Bounty with the mission of introducing breadfruit from the South Seas into the West Indies. Nelson lasted 3,600 miles of the voyage in Bligh's loyal but over burdened little launch before he perished on Timor. * See "The Columbus of the Pacific (Cook)," by J. R. Hildebrand, NATIONAL GEOGRAPHIC MAGAZINE, January, 1927. 499
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Fruit Rectangle Cakes
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LG Sciences Bulk Andro Log
39 year old advanced bodybuilder
Started cycle at 189
I decided to use this stack to gain strength while on a cutting diet. Since These products in the stack are not supposed to add much in the way of water I thought I'd try it since my goal wasn't to be in contest shape, but get stronger while getting my diet tightened up.
The Bulk Stack contains
M1D liquid
M1D Pill form
I used the recommended dosages of each product
M1D liquid 2ml 3x a day
M1D pill 3x a day
1-Andro 1x a day
FORM-XT is added towards the end of the cycle.
I utilized DC training on the two way split.
I decided to do a 4 week cycle and see how it effected me.
Here were some examples of my results:
Hammer Strength Incline started at 2 plates per side for 17. By the end of the cycle I did 3 plates per side for the same reps.
Hack Squat started out at 4 plates per side for 6 reps, and 2 plates for 20. I ended with 4 plates + 50 lbs for 10 reps, and 3 plates per side for 22 reps.
Front Squat went from 225x6 (admittedly pretty easy) to 275x8. Back squat widow maker after this went from 275x17 to 275x22.
My weight went from 189 to 185. I noticed increased vascularity, and obviously more strength. I need to get a body fat check do still and will post my results.
Overall, I'm extremely happy with this product especially if you consider that you don't have to worry about damage to your liver like you do with methylated compounds. I will definitely keep this in my arsenal with my intra workout formula.
Subbed! Kick it!
Is this the old or new formulas?
The old formulas were amazing.
SUB'd! Cant wait to see what this stack delivers.
I've spoken to people using the new stacks (all liquids) and they have said the old were better.
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Texas A&M University
Gig Em Aggies
TAMHSC- Texas A&M health science center
Located in College Station, Texas, (about 90 miles northwest of Houston and within a two- to three-hour drive from Austin and Dallas), Texas A&M's main campus is home to over 59,000 students, with more than 436,000 former students worldwide.
"As one of nine medical schools in Texas, the Texas A&M Health Science Center College of Medicine offers students an excellent medical education experience, as well as research opportunities through collaborative affiliations, combined resources and expertise from private, state and federal health care organizations. The College of Medicine trains future physicians and medical researchers to be on the cutting edge of human science, clinical skills and patient care."
Friday Night Lights
Kyle Field, home game.
Corp Kid.
This was after my brothers first week at Texas A&M. He just went thru "hell week" of the Texas A&M Corp of Cadets.
Game Day
My family likes to do things without me.
"Home of the 12th man"
Location- College station
Strong nursing program
total cost for four years- 89.88
Enrollment- 58,577
Ratio- 20:1
About TAMHSC
Things To do
Downtown Bryan
Weather and Geography
Average low- 58.9
Paying for college
The rest I will pay for when I get a job.


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Hanover will record meetings
Wednesday, May 30, 2018 by PAUL CMIL in Local News
At Hanover Township Council's regular meeting May 16, Chairman Bruce Paulus announced that council meetings would be recorded.
"We are doing it primarily so we have accurate minutes," he said.
Some townships have the audio portion of the meetings available to the public, but no decision was made on releasing the recordings to an at-large audience.
Township Manager Christopher Garges gave the latest update on road improvements.
Resident expresses concerns about airport's future plans
Wednesday, May 30, 2018 by PAUL CMIL in Local News
At Catasauqua Borough Council's workshop session May 29, Cameron Smith approached council to express his concern about both proposed expansion plans recently released by Lehigh Valley International Airport and the potential for increased traffic on Race Street.
Smith alleged schools could be taken if the airport is expanded as a cargo hub. The borough does have a representative on the Lehigh Valley Planning Commission, and Christine Weaver has reviewed the proposals made and did not find major impact on Catasauqua.
Biking through town
Wednesday, May 23, 2018 by PAUL CMIL in Local News
American Legion bike riders revved their 100-plus engines and rode into town April 20.
"This isn't a motorcycle club; we are just American Legion members who like to get out and ride," said Rich Scherb, who organized the stop at Catasauqua's Post 215. "For the most part, everyone knows each other."
Scherb led the group with his 2014 Harley Davidson Street Glide.
According to Scherb, the organization finds a veteran in need of assistance and helps them.
More questions on proposed ticketing ordinance
Wednesday, May 16, 2018 by PAUL CMIL in Local NewsCouncil has votes to pass legislation; president would prefer a better count
Councilwoman Christine Weaver is working to get Catasauqua council members to agree on a ticketing ordinance.
Council has enough votes to pass the measure by a 4 to 3 vote. A veto by Mayor Barbara Schlegel would, however, put the measure out of reach. Council President Vincent Smith would like to see a more convincing vote from council.
The ticketing ordinance is designed to give the borough an effective way to motivate residents to keep up with maintenance items that may detract from the appearance of the borough.
Burlesque takes stage May 19
Wednesday, May 16, 2018 by PAUL CMIL in Local News
The Gas House Dance Hall hosts a monthly burlesque review. The House of Knight burlesque group is one of the three reviews in the area, and its performers are returning to the 311 Front St., Catasauqua, venue May 19.
Burlesque has a literary definition used when there is a comical exaggeration of a norm. The more standard definition is an earthy comedy routine with short skits and often a strip tease.
The revue at the Gas House throws out the literary definition. There are some good lines: "If you're happy and you know it … it's your meds."
Coffee with a Cop
Wednesday, May 16, 2018 by PAUL CMIL in Local NewsChief says informal atmosphere better for borough residents
Blocker's Coffeehouse, 309 Front St., Catasauqua, hosted its first-time Coffee with a Cop event May 9.
"We had someone, who prefers to remain anonymous, who wanted to try an informal setting where residents could talk with local police. We thought it was a good idea," Police Chief Douglas Kish said.
The anonymous donor paid for the coffee for attendees, and various officers from the force, in addition to the police chief, stopped in to talk with them.
The idea is to continue the coffee shop talk in the future.
Hanover looks at FedEx traffic concerns
Wednesday, May 9, 2018 by PAUL CMIL in Local NewsWarehouse could open early even if road improvements are not complete
At Hanover Township Council's regular meeting May 2, township Manager Christopher Garges gave an evaluation on the status of traffic from the FedEx Ground development on Willowbrook Road.
There are rumors that FedEx would like to open the warehouse early even if the road improvements are not completed, Garges said.
Catty council names borough secretary
Wednesday, May 9, 2018 by PAUL CMIL in Local NewsGoldfeder continues as zoning officer; mayor commends former manager
At Catasauqua Borough Council's regular meeting May 7, council appointed borough Manager Stephen Travers as borough secretary.
The borough secretary is responsible for the information provided to council members and records the voting records. It is customary that the borough manager and borough secretary are the same person.
Council reaffirmed that Eugene Goldfeder would continue as zoning officer.
New manager talks business
Wednesday, May 9, 2018 by PAUL CMIL in Local NewsTravers says he is impressed with Iron Works, Main Streets
Newly appointed Catasauqua Borough Manager Stephen Travers took time from his busy day recently to talk about his new job.
"Everyone keeps asking me what my vision is," he said. "My job is to implement what council wants to do. Residents elect the members of council."
Travers praised the borough council members.
"I spent four hours interviewing with them, and we went on at length in different questions. One thing I came away with is that everyone on council is doing what is best for the borough. They disagree on how we get there, but that is to be expected," he said.
Training academy owner to move facility back to borough
Wednesday, May 2, 2018 by PAUL CMIL in Local News
Barry Lovelace, voted five times as the Lehigh Valley's best personal trainer, is on the move. He opened his first facility in Catasauqua and then moved to Coplay.
He plans to move back to Catasauqua.
Lovelace got his start training girls' high school volleyball teams.
"I still do team training, but that is done at their facilities. I go to them; they don't come to my place," he said.
Lovelace's techniques are unique.


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End users who violate our publishing policies should have their comments blocked or deleted. People who flagrantly violate our expectations is often banned on the moderator's discretion.
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Pastel Memories Game Gets TV Anime Adaptation
FuRyu held a special livestream presentation this week and they took the opportunity to make a few game and anime-related announcements. One of them involves the smartphone game Pastel Memories, which is officially being adapted into a TV anime. Set in a future Akihabara with …Read more »


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Army Corps Reduces Green River Flood Risk
Liz Jones
Previously, the Corps estimated a 1–in–3 chance that a flood would inundate the heavily developed valley south of Seattle. But now the odds are improved to just a 1–in–25 chance.
Mamie Brouwer is a manager with the Army Corps. She warns people in valley to remain vigilant with emergency plans, because the risk is still serious.
Brouwer: "It's dependent on the frequency of the storms, the intensity of those storms and the duration of those storms. Certainly if we get another Pineapple Express this year like we had in January 2009 we will most likely have to release water that will even top the temporary measures that have been installed."
That work includes putting a curtain of cement around a weakened part of the dam. It was damaged during last winter's heavy rains.
The Corps has worked around the clock since August to reinforce the structure, and create better pathways for floodwater drainage.
Residents, businesses and local governments from Tukwila to Auburn have been working feverishly to secure their property and the levees along the winding river.
I'm Liz Jones, KUOW News.
© Copyright 2009, KUOW
KUOW does not endorse or control the content viewed on these links as they appear now or in the future.


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text:
Projects Contrary to Strategic Direction of a Company
Company Projects that don't align with a company's core functions does not add value to the establishment. Such projects that hardly support strategic planning and growth are a waste of time.
Some organizations spend huge resources on product replacement, purchases, software change that does not enhance productivity. Valuable manpower, capital and time is lost that could be channeled into more productive areas.
Budgetary allocations, resources are better expended on strategic planning directives. The management team needs to develop projects in line with core values and strategic planning. This will guarantee better productivity and development of the company.
Improperly Managed Project
Any project a company embarks on is to increase productivity and ultimately profit. Crisis management is entirely different from risk management.
Crisis management is when project managers endorse a project and unforeseen disaster occurs. They struggle to find solutions that are none tested and could add to the problem.
Risk management involves proper analysis, projections, troubleshooting and identifying risk factors. This is done throughout the entire project with provisions for such challenges.
Proactive risk management reduces risk, controls unforeseen occurrences and cushions the magnitude of such risks. Risk management is done before the commencement of a project and is crucial to the success of the enterprise.
Continuous risk management protocols are essential throughout the life time of a project. This is usually done every couple of months and drastically increases safety and success of the project.
In the likelihood of crisis, project auditing is an essential requirement to get back on track.
Insufficient Project Plan Details
Poor detailing could cause major setbacks to a project. Time wastage, schedule details and low moral of staff/workers are the offshoot of such lapses.
High level of detailing is a mandatory requirement for project planners. Their job is to identify risks, challenges, project duration, including amount of resources expended on each stage of the project.
A highly detailed project plan reduces risk, project duration and increases productivity.
Project Scope
Having an unclear project scope is tantamount to failure. Such lapses lead to change in core project values and character.
Most project mangers use basic presentation materials that don't go into detail and lacks future projections or a scope statement. Such presentations are merely generic and lack dept of proper execution.
To solve this problem the project team and manager needs to work together in synergy. The project manager should leverage on the technical experience and knowledge of co-workers.
Having a proper scope statement provides valuable impute and future projections. Changes are referenced to approve the 'scope statement' and determined cause of action. Make sure the scope statement is approved by the sponsors before execution.
Engagement of Inexperienced Project Team
Engagement of the wrong or inexperience project team affect the project. To avoid this pitfall develop a competency assessment strategy to identify performance, ability and knowledge base of the project team.
Another way is to provide adequate training, seminars, coaching and mentoring programs.
Project Structure
Project teams need to coordinate properly and maintain communication. Large project teams would face communication challenges and delayed result.
The workable project structure should consist of project leaders, project teams in charge of different facets of the project. The entire project is then divided into sub projects independent yet aligned with the major project.
This offers efficiency, accountability and good project management.
Project Management Template
A company needs to maintain consistency in project management. They need to develop best practices, structures, frameworks, tools and techniques.
Other requirements include proper time management, reusable templates and proper planning. This will offer consistency in administering future projects.
Work Performance Review
Work performance reviews are generally done according to job description. This doesn't take into consideration project assessment, recognition or putting in place a reward system.
Without such reviews employees tend to operate assignment in a lackadaisical manner. If the job review and performance is incorporated into the total performance of such individual they would perform better.
Companies must embark on constant training of staff. This is to provide a clear understanding of job description and function.
The training offers insight to new technologies, techniques and better management of projects. It also provides them the knowledge and skills required to successfully plan a project.
Determine Project Goal
The company needs to determine the project goal. Understanding the requirements, objectives and goal provides a blueprint to succeed.
Over budgeting and under budgeting are other problems that companies face. Regular review of current prices and working environment will reduce this factor.
Project Planning and Management Mistakes
- No clear goals
- Insufficient and poorly allocated resources
- Unexpected problems
- Scope creep
- Underestimated initial costs
- Inadequate budgeting and monitoring
- Cost mistakes
- Assigning the wrong project manager
- Poor training
- No work performance review
- Poor communications
- Unaided project manager
- Poor management of project scope
- Need micro-project management


text:
YOU ARE WATCHING: Race 3
Have a nice day! All The Best
Race 3
Relationships and loyalties of a criminal family planning its next big heist are tested when some shocking revelations strike them.
Genres: Action, Thriller
Actor: Anil Kapoor, Salman Khan, Bobby Deol, Jacqueline Fernandez
Director: Remo D'Souza
Country: India
Movie: Race 3
Production Co:
Duration: 160 min
Release: 2018
Server OpenLoad
Server FlashX


text:
If you are looking for a new laptop to buy, there are many options available for you out there. Majority of the market is filled with business-focused laptops that you will find at very cheap to very high price. But if you are a gamer just like me and many of us, you would obviously prefer a laptop with high RAM, a dedicated graphics card, good screen and huge hard disk storage. Such kind of laptops with such specification exist, but they are very costly and not for everyone and if you have a tight budget.
However, there are very few laptops that you can use for gaming, but you can't expect everything from them. But there is now there has been the latest addition to the budget gaming laptops that you can consider if you are planning to get a gaming laptop for you and that too without spending too much money.
We are talking about Origin Eon15 laptop that has been manufactured by the company for good gaming experience at a low and entry level cost. Here we are going to tell you the pros and the cons of the Origin Eon15-S laptop so that you can decide whether to go for it or not.
Origin Eon15-S Laptop Specifications
Eon 15S has a screen size of 15.6 inches featuring an IPS LED display panel with full HD 1080p screen resolution. The laptop has a dedicated Nvidia GeForce GTX 1050 Ti graphics card installed for playing the latest and heaviest of games in the market. There are two versions of the laptop available. Origin has included 8GB DDR4 RAM in the laptop assisting the Core i3-7100H dual-core processor in the first and the basic one which is priced t $999. The Core i3 processor has been clocked at 3.0 GHz. However, the other better version of Origin Eon15-S laptop is more powerful and possesses Core i5 processor assisted by 16GB DDR4 RAM. This better version of the laptop will cost you $1350.
- Display: FHD IPS Display
- Resolution: 1080p Full HD
- Graphics Card: Nvidia GeForce GTX 1050 Ti – 4GB
- Processor: Intel Core i3, Intel Core i5
- Hard Disk Storage: 240GB Solid State Drive + 1TB Seagate Hard Drive
- Fingerprint Reader: Integrated Biometric Fingerprint Reader
- Camera: 2 MP FHD Front Facing Video Camera
- Weight: 5 lbs
The laptop has specifically been made for the latest and modern games that could run easily in between 30 to 60 frames per second. The 1080p screen resolution produces great and detailed images. We tried some of the latest games like FIFA 18 and Rise of Tomb Raider at low FPS and normal to high setting and ran pretty well. However, you can really play with the setting to make the games smoother, you will have to compromise with the visual quality then. But, we didn't find too many problems while playing the games, as most of the games will run butter smooth in normal visual settings.
Things We Liked About It – Pros
- The Display: First of all, we really loved the display that it offers. Most of the gaming laptops drop the most important part, the display to bring the price down. That is not the case with Origin Eon15. The LED display in Eon15 is bright, colorful as well as very sharp. Playing games on this laptop is really great.
- Nice Looks: You will love the laptop as soon as you see it. It has really great design and it looks classy and premium in black chassis. The logo adds up to its look and is perfectly placed. The outer casing is strong as well but lightweight, making it a good portable gaming laptop. There are other designs as well which are available which the users can pick. These custom designs are really good and add the gamer feel to the machine.
- The Keyboard: The Origin Eon15 does not come with a mechanical keyboard and we loved it. The keys are fairly apart not giving you the mushy and constrained feeling you get from other laptops with small sized keyboards. There is RGB backlights also present that will help you to play the games even in the darkest of room. Another thing great about the keyboard is the Numeric Pad. Most of the laptops do not offer numeric pads on their keyboard for one or the other reason. But it is always better to have something extra. Also, it is helpful for players who use numeric pad while playing games.
- The Connecting Ports: Origin Eon15 has a lot of ports and many options for connection. There are two USB 3.0 ports and one 2.0 USB port. There is USB Type-C port as well along with a memory card reader. You have a standard HDMI port as well. But what came as a surprise was a couple of mini DisplayPorts. These ports also support the Nvidia GSync technology and the users can also add a couple of monitors to this laptop.
What is Not Good – Cons
- Sound: There are definitely other laptops out there that can produce better sound when compared to Origin Eon15. The sound output of this laptop is really low. If you are present in a crowdy place or in a noisy area, it is very hard to listen to what is coming out of it.
The Verdict
The Origin Eon15 is a good gaming laptop with really great features, specifications, and display. It is cheap as well when compared to other premium gaming laptops like Alienware. The great connectivity options make it a good contender in the budget gaming laptop section. The looks are great, you get a lot of options to choose from, and you also have two different variants that you can look up to. There is nothing more we can ask from a good budget gaming laptop.


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Anyone else's lo eat so much at meal times? She'll have half an avacado, 5 strawberries, and a cup of yogurt. Or a whole peanut butter sandwich made with 2 pieces of bread, a whole gerber ravioli tray, and a fruit bar. Or at dinner the other day she ate a whole slice of pizza! Are your los eating this much?
Some days it feels like all she does is eat!
We went out the other day for dinner with visiting relatives, and she ate 2 slices of our pizza. And this was after she'd had peas, strawberries, and half a pouch. The relatives just kept saying "ooh, she loves her food, hey?"
She's not even that big. I figure she's moving and growing SO MUCH, she just needs the energy. And I want to encourage a healthy relationship with food, so I'm not changing a thing!


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I am just 1000% opposed to promoting multipurposing the TIPI's PI.
To each their own. I have lots of counter arguments, but none of that has to do with gcc.
(Does anyone really think I waste any time transferring files in my dev workflow when there are 200 ways to automate that for Unix to Unix?)
I can respect your stance on further multi-purposing of the tipi-connected Pi, especially since in increases the likelihood of problems and need for support which is outside the scope of TIPI, but people might still expect you to help.
Also - No, I didn't imagine you were manually copying files. I was referring to the transfer time required, automated or no


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Duathlon launched
03 December 2007
The Chelsea and Westminster Health Charity's sponsorship of the world's largest duathlon—a mix of running and cycling – was officially launched in November.
The Chelsea and Westminster Health Charity London Duathlon will take place in Richmond Park on Sunday September 14 2008 and staff, volunteers and everyone connected with the hospital is being urged to get involved.
You can register to take part by visiting www.thelondonduathlon.com—there is a 'fun' distance for beginners, a 'challenge' distance for the more adventurous and even a kids distance for youngsters.


text: I'm currently in flight training. Since I one day hope to own a twin piston aircraft EX: Cessna 310, I've started to wonder how I could help pay for that or for other types of planes that can cost considerable amounts in running costs. My question is, what have you had to do to afford flying? Have you had to make sacrifices when it comes to other toys or housing? Have you started a side business to fund your flying? What career path are you in that's enabled you to have your own personal plane? Etc. Edit: Please mention the type of plane you own. I'd also be especially interested about how if anyone on here has personal planes that cost them 80k+. Disclaimer: I know about partial ownership options, but for the sake of this post, please only talk about how you've afforded to completely own your own plane.


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After the owing day has handed and also you open an assignment, you're alerted that your submission will likely be marked late.
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As we focus on constructive plans (what we really need) in place of what we don't need (old behaviors), we get more robust. A center on abstinence can result in the quite rigidity that is the hallmark of a traditional taking in problem. As we use the Ways to deliver peace and point of view--and choose smaller, very careful pitfalls to develop rely on with ourselves--we learn that Restoration, like pleasure, is usually a by-product of contemplating and executing the following correct detail (regardless of check this what that read here could appear to be in the intervening time).
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Are you searching for a way to surprise and seduce your lover the next time you are in bed? This elegant nighttime set includes a sultry, classically styled pinup chemise and a matching G-string that will help you open an entirely new sexual realm. Any loose-fitting dress that hangs straight from the shoulders is popularly known as a chemise. This gorgeously designed floral chemise is further enhanced with a ruffled hem and a center front bow. This small-medium variant is perfect for females with a bust size of 30-34 inches and a waist size of 24-28 inches. The cups in the chemise will provide a custom fit that will surprise every woman who tries it. Not only does the lingerie set hide all the problematic areas, it is also designed to highlight your body's assets without giving too much away.
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No organization is more dedicated to keeping working people in their poorly paid place than the Chamber of Commerce. The U.S. Chamber has now issued a report finding that the road to prosperity leads through Mississippi. Is that counterintuitive or what?
A CofC paper on "The Impact of State Employment Policies on Job Growth" gave Mississippi a "good" rating, because it has few union members, low unemployment benefits, and minimal regulation of wages and hours. A more objective study of life in Mississippi, this done by the Census Bureau, finds that the state ranks dead last in per capita income. Other scholarly studies show Mississippi on bottom in public education, child welfare, and just about everything else that makes life worth living. The American Human Development Project, a nonpartisan effort to measure human well-being in America, finds Mississippi in 49th place, ahead of only Guess Who and West Virginia. (Arkansas got only a "fair" rating from the CofC. They like our "right to work" law, but seem to believe we're not doing enough to make people work longer for lower pay.)
What's good to the Chamber is bad for the people. And yet the people of Little Rock are forced to subsidize their enemy. The Little Rock Board of Directors slips $200,000 of public money to the Greater Little Rock Chamber of Commerce every year. It's indecent, and it must be stopped.


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The Greatest Guide To fitness body
Remote Monitoring [ This band allows one particular remotely track the crucial stats of even the family members. Also, this sends notification to guardians incase any vitals transcend regular level - life conserving aspect]
By subscribing to our newsletter, you consent to acquire new post updates and occasional promotional emails associated with our business.
The appropriate fitness tracker are going to be determined by your specific wants And just how active your lifestyle is. Some will just look for step counting and reliable slumber tracking, Other people want crafted-in GPS for running, a coronary heart fee keep an eye on to deliver Innovative resting coronary heart level information. The nice news is that there is some thing around for everybody, even without breaking the bank.
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Should Your Elderly Parent Be Driving?
A big part of a non-medical elder care expert's job is often helping elderly people make transitions. More than any other activity, driving is directly linked to a senior citizen's independence. It takes one back to the days of youth and freedom. But driving privileges must be discussed if your elder is driving erratically or showing bad judgment that can put their life in danger or the lives of others. Having driving difficulties usually come from the natural physical deterioration we all experience as we age. This can include poor vision, reduced hearing, slowed reflexes and many other things that negatively impact our driving ability.
Even if the elder you are caring for is competent behind the steering wheel of a car, having them retested at the Department of Motor Vehicles is not a bad idea if you are concerned.
Here are 5 important questions to answer if you are concerned about your aging parent driving a car.
- Are they a good driver during the day but not at night?
- Do they have 20/20 vision with corrective lenses but have drastically reduced peripheral vision?
- Does your elderly parent do well driving locally but has a hard time at higher speeds or when directions are needed?
- Do they hit curbs, miss turns, or put pedestrians at risk on a regular basis?
- Have they been in a car accident that has been deemed their fault?
If you can answer "yes" to any one of these questions it may be time to seriously consider taking them off the road. But don't just take away the keys. Be sensitive to the situation and plan on how you are going to take away the keys. Try to involve them in the process.
No longer being able to drive could cause many problems for your elder, such as loss of their primary source of getting places and the ability to easily purchase food and bring it home. They could now find it hard to attend social events or help friends. The loss of being able to drive can also increase their anxiety level due to both real and imagined isolation.
Because giving up driving can be traumatic and greatly impact your aging parent's daily life it is not something that should be taken lightly. Do you have an elderly parent or loved one who needs help with everyday tasks or just some companionship? LifeWorx can help. All of our Elder Care Experts have over 2 years experience and are fully screened and vetted.Contact us today.


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My heart is hurting. My stomach is in knots. The mountains surrounding my hometown and where I grew up, are on fire. Over 220,000 acres have burned and it's still growing. Soda Fire 2015. A horrible inferno caused by lightening. It's one of the largest fires in the nation right now. It has been burning since early Monday morning.
|Photo by Frank Sorger view from Lake Lowell
Many of my friends and family have livestock that graze in those mountains. Ranches, homes and cabins have been threatened. Several people have been evacuated. Roads and highways have been closed. Buildings have been destroyed and animals have been lost. It's such a devastating thing to see.
|Photo from Soda Fire 2015 Facebook Page
|Photo by Dan Roeser
The firefighters are working hard to try and contain it and many of them are people I know fighting the fire and trying to protect their land. The air is thick, brown and so smokey. Ash is falling down. When you are on the highway you can't even see those beautiful Owyhee mountains, just a thick blanket of smoke. And those flames, they are visible for miles.
|Photo by Charlene Aycock view from Lake Lowell
|Photo by lawde13
|Photo by Debbie Cleaver view from Eagle, ID
|Photo by Kallie Roeser at Roeser Ranch
I am normally an optimist, but I just can't seem to get passed this. I am so sad. I've been glued to my tv watching the news reports and live broadcast. Facebook is a constant stream of videos and pictures of fire, devastation and close calls.
I am praying for my community, my family and friends who have been affected, and for all those who are fighting this fire. Wind gusts and dry lighting are expected tonight. I just hope God sends us rain. Pray for Idaho.
|Photo by Toni Slack the mountains Monday afternoon before the fire grew to over 220,000 acres


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- Contact vCash
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Their toll free phone number is 1-877-513-7505.
Their website is http://www.VCASHPOS.com
[vCash Group will no longer answer or service the POS debit terminals.]


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BY Tom Burke | Colombia | 1/26/16
As the Colombian peace process enters its final months of negotiations, the Colombian government set Liliany (Lily) Obando free the week of Jan. 22.
Message from Hubert Ballesteros, Colombian unionist and political prisoner, to North American labor and solidarity activists
BY staff | Colombia | 1/24/16
The following message is a response to a series of questions posed to Hubert Ballesteros by James Jordan of the Alliance for Global Justice. Ballesteros was arrested while negotiating for the National Agrarian Strike of 2013 and charged with rebellion.
BY Kait McIntyre | Havana, Cuba | 11/26/15
Nov. 24 was the second day of the fourth International Seminar for Peace and Abolition of Foreign Military Bases, held in Guantanamo Province. There were several presentations made by select delegates as well as group discussion.
BY Jessica Schwartz | Columbus, GA | 11/24/15
Students for a Democratic Society (SDS) and anti-war activists from college campuses in Tampa, Gainesville and Tallahassee, Florida traveled to Columbus to protest the School of the Americas (SOA) on Nov. 20.
BY Tom Burke | Columbus, GA | 11/22/15
A large group of anti-war and international solidarity activists passed out hundreds of flyers at the annual School of the Americas (SOA) protest at Fort Benning, Georgia on Nov. 21.
BY Vera Lynn | Houston, TX | 11/19/15
Over 50 people gathered at Solidarity Houston, a left-wing book store, Nov. 19, to discuss Simon Trinidad and the Colombian peace process. The event was organized by the Houston Anti-War Coalition and included three panelists who spoke about the history of the Colombian left, the Colombian rebel group FARC-EP and the U.S. imperialist war on Colombia.
BY staff | Florence, CO | 9/22/15
In the mountains of Colorado, 35 spirited protesters marched down Highway 67 to the guardhouse of the U.S. federal supermax prison in Florence on Sept. 21.
BY staff | United States | 9/08/15
Students for a Democratic Society stands with Simon Trinidad and the peace process in Colombia. Simon Trinidad is an important political leader in the Revolutionary Armed Forces of Colombia-People's Army (FARC-EP).
BY Tom Burke | Denver, CO | 6/27/15
Hundreds of anti-war and international solidarity activists called the White House, June 25, with a message for President Obama, "Peace for Colombia! Free Simon Trinidad!"
BY staff | Colombia | 5/26/15
Fight Back News Service is circulating the following statement from the Revolutionary Armed Forces of Colombia – People's Army (FARC-EP).


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The preparations are in full swing in both the camps as India and South Africa await the start of the first Test at Cape Town on January 5.
And as players from both teams sweat it out in the net sessions ahead of the Test series, we bring you some of the best pictures.
Cape Town's worst drought in decades may take some of the sting out of the Newlands pitch for the first Test between South Africa and India, starting on Friday.
There was a covering of green grass on the match surface when both teams practised on Tuesday, bringing a smile to the face of South African coach Ottis Gibson.
But groundsman Evan Flint said the grass was thin and that the weather conditions had made it difficult to produce the seam-friendly surface which the home side would like.
There was some unseasonal light rain on Sunday and Monday – about four-and-half millimetres in total – but not enough to break the prolonged drought.
"It made conditions a bit quicker," said Flint
Flint has had to use borehole water and has been restricted to watering the outfield only twice a week, which means the playing area is drier under the surface than usual.
"I think if the fast bowlers bowl well enough, there will be something in it for them," said Flint. But he did not expect conditions would give a lot of assistance to South Africa's pace attack.
"It depends on who adapts quicker on the day – it is not necessarily favouring anyone," said Flint.


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…that I get when Hungry Harvest sends me a confirmation email telling me what to expect in my delivery box this Saturday.
Naturally, I have already customized my box. I did it almost immediately after the last email I got that told me customization for this week's box was open.
Add a dozen eggs (I'm a baker and I'm a runner – I always need eggs), take out a few apples (only because I have TONS already at home), and oooooooo! There are leeks this week!
And grapes.
And zucchini (I'm totally making bread).
And a type of tomato I've never heard of!
Check, check, check. They all go in the box.
I clicked "Save" and went about my day.
This morning, though, my confirmation email reminds me what will be in my delivery, and (my favorite part) it tells me WHY each items was recovered.
These ones look a little uglier than others, but they are still good and tasty.
The buyer who wanted these ordered too many, so we have the extras.
These ones are just a touch small, so just add two to your recipe.
I've calculated before how much money I've saved getting rescued produce and it usually falls in the neighborhood of $50 per month. And for my little family of two, $50 is kind of a big deal.
Plus it's fun to let the preschooler color in the box afterwards.
Want five bucks off your first box? Use code: HERO5 on your order!
I am a Hungry Harvest ambassador, which means I am part of a community that really loves talking about Hungry Harvest.
Featured photo by Elaine Casap on Unsplash


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Ideas Platform For Seed Ideas
Idea Seed is the perfect place to validate and sense check your new startup venture. Whether you're launching a new Fintech/ eCommerce Startup or you just have a great idea for a new mobile app. If you come up with 'great ideas' on a regular basis you can store them privately in one easy to view dashboard.More "Ideas Platform For Seed Ideas"
Can your HR Stack help you win the War for Talent?
Data…. We are all now part of the data revolution, whether working in Marketing, Sales or Management; dashboards have become a crucial part of all our workflows. But what about HR, where managing employee's feelings and sentiment about the company; cohort analysis and reducing staff turnover are major challenges for HR professionals?More "Can your HR Stack help you win the War for Talent?"
Radiooooo SuperCharges Your Music Discovery
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Dog Boarding
House Sitting
Drop-In Visits
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Hosting Preferences
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No Females in Heat
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About Zoe
Happy to go on long walks!
My name is Zoe and I grew up in Vancouver and moved to Toronto just over a year ago for school. I grew up with dogs my whole life, including a Collie and a Belgian shepherd/ Husky mix who both passed away from old age. My mom still has our cavalier back at home in Vancouver but since I now live in Toronto in an apartment I am missing having a dog! Since I travel ...
What Zoe would like to know about your dog
Temperament and how they react to other dogs and people.


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This morning I found out something pretty worrying, and I almost got sick to my stomach worrying about it so much. I mean, this thing is pretty important, but worrying about it isn't going to help a thing.
Who of you by worrying can add a single hour to his life?
Matthew 6:27 and Luke 12:25, (NIV)
(It was so important, this question was in the Bible twice!)
(It was so important, this question was in the Bible twice!)
Once I realized this, I turned my attitude around and started praising God instead of getting upset at Him (even though this thing is not something He is responsible for).
James 4:7 says, Submit yourselves, then, to God. Resist the devil, and he will flee from you.
I started to resist the devil. There was no way he was going to rule over my thoughts! Once I started praising God for His blessings, the devil left. He fled. He couldn't bother me anymore because I wasn't giving him that foothold (see Ephesians 4:27).
It's so easy to see why Paul and Silas praised God by singing in prison! (Acts 16:25.) Satan was not able to bother them when their focus was on Christ.
God has been teaching me a lot lately, mostly about worrying and words.
I sin so much in my speech, and it's something I've become immune and almost oblivious to. I am sarcastic and critical. I don't build others up. I tear them down! Sometimes I can say something that isn't necessarily critical or rude, but my tone of voice is not kind and loving. God has been convicting me of this a lot recently.
Ephesians 4:29 (NIV) --
Do not let any unwholesome talk come out of your mouths, but only what is helpful for building others up according to their needs, that it may benefit those who listen.
Oh dear. Is my speech benefiting those who are hearing it? Not always. Something needs to change.
This is my argument for cussing. I can't stand cussing.
Some people call it a "gray area" but it seems like the Bible is pretty clear on this.
Is it benefiting those who listen? No.
Is it helpful for building them up? No. A lot of people are actually offended by cussing.
Read this:
Let all bitterness and indignation and wrath (passion, rage, bad temper) and resentment (anger, animosity) and quarreling (brawling, clamor, contention) and slander (evil-speaking, abusive or blasphemous language) be banished from you, with all malice (spite, ill will, or baseness of any kind).
Ephesians 4:31 (AMP)
I think we could all agree that cussing is "abusive" and can be put in the "malice" category.
Plus, if we are living our lives to glorify Christ, and we come across a controversial "gray area", don't you think we would want to stay as far away from it as possible? If we don't know whether or not cussing is a sin, and we want to honor God, shouldn't we just stay away from cussing altogether instead of doing something that we're not really sure God approves of?
Just a thought.
And I'm still learning. I need to practice what I preach!
Do you ever get excited about new weeks? I think a lot of people tend to dislike Mondays, because it means another 5 days before the weekends. But I like Mondays. It's a new start, a new 7 days, a new chance for God to teach me something. The weekends are fun and all, but sometimes I feel like I'm wishing my life away by always looking forward to them.
I realized today how close graduation is (less than 16 months) and I got sad again. I tend to get sad when I think about graduation, because I love college so much. I realized that I need to savor every moment that I have here, and look for opportunities to share Christ's love with others while I'm here. Time is precious!
I have never walked under the Century Tree, but I have always wanted to. I think it's such a beautiful tree.
I don't want to be proposed to under it, though. Come on, guys, think of something a little more creative! :) I can understand that it's special because of the tradition the corps has, but still... think of something different.
Class starts pretty soon, so I should probably go collect my printouts and be on my way.
Have a beautiful Monday. Enjoy the day that God has blessed you with!
- Katie


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She underwent breast reduction surgery rather than the conventional breast enhancement surgery that most women want.
I assume it will be targeted toward teens, but as a 36 year old, I really enjoyed it.
Depp has taken on the task of challenging himself to portray "larger-than-life" roles, starting with a supporting role in Oliver Stone's Vietnam War film Platoon in 1986, then playing the title character in the romantic dark fantasy Edward Scissorhands (1990).
He later found box office success in the fantasy adventure film Sleepy Hollow (1999), the fantasy swashbuckler film Pirates of the Caribbean: The Curse of the Black Pearl (2003) and its sequels, the fantasy film Charlie and the Chocolate Factory (2005), the fantasy film Alice in Wonderland (2010) and voicing the title character in the animated action comedy western Rango (2011).
His parents divorced when Depp was in high school, and Depp soon dropped out to pursue music full-time.
Rechristened The Kids and later Six Gun Method, the band moved to Los Angeles, and had their biggest moment as an opening act for Iggy Pop.


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GSO Spring Speaker 2012
Bayesian Nonparametric Models Using Lévy Random Fields and Overcomplete Dictionaries
Merlise Clyde
Department of Statistical Science, Duke University
Start Date and Time: Fri, 2 Mar 2012, 10:30 AM
End Date and Time: Fri, 2 Mar 2012, 12:00 PM
Venue: SC239
Lévy random fields, although less well known than Gaussian random fields, are ideally suited for constructing nonparametric prior distributions on unknown functions using expansions with overcomplete, and in particular, continuous dictionaries. In this talk I will provide an overview of constructing nonparametric priors distributions on functions using Lévy random fields and how these relate to the more familiar compound Poisson process and limits of other finite dimensional expansions, in particular kernel regression and support vector machines. Under suitable conditions on hyperparameters, the resulting functions are able to adapt to unknown smoothness and sparsity similar to wavelet models. In fact stochastic expansions using continuous wavelet dictionaries may be viewed as a special case. I'll review key theoretical results and provide practical details about computational implementation. Finally, I'll illustrate the methodology using MALDI-TOF mass spectroscopy data, air pollution fields (space and/or time), and other classification problems from machine learning and close with open problems.


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Latitude: 52.4228 / 52°25'22"N
Longitude: -0.8004 / 0°48'1"W
OS Eastings: 481669
OS Northings: 281209
OS Grid: SP816812
Mapcode National: GBR CVL.2FM
Mapcode Global: VHDR8.2CPJ
Entry Name: Rothwell Market House
Listing Date: 12 June 1950
Grade: I
Source: Historic England
Source ID: 1288812
English Heritage Legacy ID: 398698
Location: Rothwell, Kettering, Northamptonshire, NN14
County: Northamptonshire
District: Kettering
Civil Parish: Rothwell
Built-Up Area: Rothwell
Traditional County: Northamptonshire
Lieutenancy Area (Ceremonial County): Northamptonshire
Church of England Parish: Rothwell with Orton Holy Trinity
Church of England Diocese: Peterborough
9/78 Rothwell Market House
Market House. 1578. Built to the designs of William Grumbold for Sir
Thomas Tresham. Completed for use as Council Chambers and Library,
1895, by J A Gotch, and restored 1913. Limestone ashlar with lead roof.
Chamfered plinth, moulded sill band, first floor band with Latin
inscription, parapet with frieze of shields. Pilasters in 2 orders,
decorated with trefoils and heraldic devices. Single side wall stack. 2
storeys, the ground floor originally open. Rectangular plan with a 2-
storey projecting square bay in the centre of each side, and a round
stair turret at the south east corner. North front has a central doorway
with fanlight and above it, tablet inscribed 'Urban Council Chamber'.
Above again, a clock. On either side a round headed opening with C20 3-
light wood mullioned and transomed windows. Above, 2 C16 4-light
mullioned leaded casements. Similar south side has above the blocked
doorway a crest and above it, a blank lozenge. On either side, round
headed openings, that to left blocked, that to right glazed. Above, a 4-
light and a 3-light mullioned window. The stair turret has, above, a 3-
light and a 2-light mullioned window. East side has a round headed
opening to the right with a part-glazed C20 infilling panel and a 4-
centred arched door. Above, a 4-light mullioned window. West side has a
central round headed opening with a 3-light mullioned and transomed
window. Over it, a square blank panel. Above, a 4-light mullioned
Listing NGR: SP8166981209
This text is from the original listing, and may not necessarily reflect the current setting of the building.
Other nearby listed buildings


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It's that time again! Jim Cramer rang the lightning round bell, which means he gave his take on caller favorite stocks at rapid speed:
Pacira Pharmaceuticals: "I know this company...they did have some news recently. I've got to parse the news because half the people said it was good, and half said it was bad."
Chevron Corp: "Chevron I think is okay, the dividend, I think you would sell the stock here. It's having a little bit of a bounce. I would sell it into the bounce. There are better, higher quality oil companies that are down much more."
Neophotonics Corp: "Lightweight circuits. This is very hard for me, I am not going to be able to make a snap judgment on this company. I wish I knew it better, I've got more work to do."
YRC Worldwide: "No, not with United Parcel under pressure. I think United Parcel has a much better situation, that's what I would go with."
Blackrock Inc: "I think Blackrock does a terrific job, they've got a lot of good interesting products. I know there were some interesting statements back and forth at Delivering Alpha, but when it comes to a well-run company—Blackrock is a well-run company. That's what I care about."
Mobileye NV: "I'm going to see you on Mobileye and I'm going one better, I want you to think about Ambarella, which has got a lot of the intellectual properties that I like about Mobileye but also has drones."
Read more from Mad Money with Jim Cramer
Cramer Remix: When to take a bite out of Apple
Cramer: Growth stocks to grab in the next selloff
Cramer game plan: Oh my! Earnings are a minefield
Alcoa: "Remember what I said: When this deal closes is when Alcoa is going to go up. The deal must close first. When it's closed, you'll get a revaluation and re-ranking and that's when Alcoa will go higher."
Insys Therapeutics: "We looked at this stock and have a very high feeling for it. We think it is speculative but it's a good one."


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Match the extent of the project's complexity While using the respective functionality amount of the project manager
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|Home | Faculty & Research | News | Undergraduate Program | Graduate Program | Courses | Seminar Series | Contact Us
Undergraduate Program
Undergraduate Program: Research Opportunities: REU Program
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The application can now be completed online. Completed applications must be received by February 16, 2018. Award announcements will be made beginning March 16, 2018
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When: Tue., July 28, 6:30-8:30 p.m. 2015
Milkweeds represent one of the more unique groups of wildflowers in Texas. Join TPWD's Craig Hensley for a look at the characteristics and diversity of milkweeds in Texas with a focus on the Hill Country. You'll also learn about their relationship to monarchs and queens and the host of other insects that utilize these plants.
Price: Free


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About this item
- Comes with 6 clear plates
- Clear plastic plates can be tossed away or washed and reused
- Brings a touch of elegance to any party
Bring easygoing elegance to your table setting with these Clear Dinner Plates from Spritz™. Whether you're hosting a family dinner, friendly get-together or a big celebratory bash, these clear dinner plates will make the perfect addition. From appetizers to the main course to delectable desserts, these plastic plates will add sophisticated style to whatever you're serving up.
Features: Round (shape)
Material: Plastic
Dimensions (Overall): 10.2 inches (L) x 10.2 inches (W)
Pattern: Printed pattern
Package Quantity: 6
Item Number (DPCI): 053-21-2532
Origin: Imported
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Yoga Burn Booty Challenge - How to Get a Bigger Butt in a Month
Exactly what makes the Yoga Burn Booty Challenge reliable? The secret to the efficiency of the Yoga Burn Booty Challenge depends on the cutting edge 3 action Prime, Activate, Pump method which was established based upon the tried and tested principal of dynamic overload. P.A.P is the facility piece of this distinct follow-along from house difficulty as well as is made to ensure the ideal workout is being done, in the ideal order, for the correct amount of time to flawlessly target and also function the whole booty to the max to make sure that you get the greatest results possible out of each and every single exercise. When utilizing the one-of-a-kind 3 action P.A.P approach, just your very own body weight is needed as the single resource of resistance without the need for any gym tools whatsoever. Who is Yoga Burn Booty Challenge For? The Yoga Burn Booty Challenge is for women between the ages of 18-65 including absolute newbies to physical fitness, working out as well as yoga exercise. This challenge can be equally as efficient for ladies that have actually been into physical fitness and yoga exercise their while lives. * Please consult your healthcare service provider before starting any fitness program. Suppose it does not benefit me? That's an easy one. Pay attention, if you are not totally pleased with this program or your experience for any factor whatsoever merely send us an e-mail or call us using our toll free number within 60 days of your purchase and you will certainly be issued a no-questions-asked 100% reimbursement within 48 hours. If you purchased the physical variation of this program, you may simply return the item anytime within 60 days of your acquisition and you'll receive a complete, no questions asked refund. Who Is Zoe Bray-Cotton? Zoe Bray-Cotton is a worldwide certified individual fitness instructor, yoga instructor and women transformation expert. Zoe is the designer of international best selling health and fitness systems for reference women such as Yoga Burn. Zoe Bray Cotton What if the exercises are as well tough for me? I've made this program to be able to match women of all physical fitness degrees from very new novices to advanced. You could go at your very own speed as well as take breaks as needed. This difficulty was created in 15 min periods for this very objective. How much time will this deal be available? My finest suggestions is to make the most of this deal currently while we have supply and can ensure our cheapest price along with the special perk collections being included today. Who is the merchant of The Yoga Burn Booty Challenge? Click financial institution is the merchant and also settlement cpu of the Yoga Booty Challenge. Click financial institution is considered as a relied on globe leader in safe and secure electronic shopping and also has actually safely refined lots of billions in globally deals considering that 2001. Click financial institution has numerous multi-lingual customer care agents offered to assist customers in any time area and also from any type of area worldwide every day. Exactly how do I know it's secure to utilize my charge card on line? Credit card security is exceptionally crucial to us. That's why we've partnered up with Click bank to take care of all your billing utilizing their safe outlet layer, 128 little bit security. Truthfully, your charge card data is more secure making an on line purchase via our protected website than it is utilizing it to pay for gas or acquire food at a restaurant. So really feel comfortable Full Report recognizing your deal is 100% entirely safeguarded from fraudulence.


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The products combine powerful technology with innovative applications for mobile imaging, music, communications and entertainment. Sampling Technique — Random Sampling technique f. Factors that influence decision-making in purchasing a mobile phone. The trend of beating industry norms started with the fastest ever-nationwide launch by MOTOROLA in a period of 4 and 5 months with the commencement of operations in May This could be pricing, location of sales, reception, colour, memory, or anything else.
It was an exclusive provider of domestic and longdistance service that would be its own regulator separate from the postal system. The global mobile phone industry is based on many different manufacturers and operators. Slowly and steadily, Nokia became a large television manufacturer and also the largest information technology company in the Nordic countries.
Strategic agreement with partners such as Sony BMG is one way in which the company is bringing the best and latest in entertainment content to its users. Before the corporate name change to LG, household products were sold under the brand name of Lucky, while electronic products were sold under the brand name of GoldStar.
In addition to these companies there are many manufacturers that operate globally and locally.
Cellular services can be further divided into two categories: The net result is that Sony Ericsson is an enticing brand that creates compelling business opportunities for mobile operators and desirable, fun products for end users. Generally, cellular telephone service is available in urban areas and along major highways.
National Telecom Policy NTP was the first attempt to give a comprehensive roadmap for the Indian telecommunications sector. Sony, which had not invested in LCDs, contacted Samsung to cooperate.
Telecommunication sector in India can be divided into two segments: Effectiveness study improves the overall performance of the company. I express my gratitude to the Director, Mr.
Sony Ericsson Mobile Communications was established in by telecommunications leader Ericsson and consumer electronics powerhouse Sony Corporation. Over the years, Nokia has evolved from a pulp, rubber and cables manufacturing company to a major manufacturer of wireless devices and networks.
It also provides equipment, solutions and services for network operators, service providers and corporations. The most viewed form of media is Television and it is also the most effective form. About mobile phones 6 Which mobile phone you are using. Many consumer electronics were sold under the brand name GoldStar, while some other household products not available outside South Korea were sold under the brand name of Lucky.Essay.
UPLOADED BY stewie72ms. PAGES 6 RATINGS. View Full Document.
Brand and Product Management Scenario Analysis Paper that must be followed by all their distributors and manufacturers, and not just to their phones, they needed to rebuild their brand for cell phones as well. Brand Prefference of Mobile Phones.
A STUDY ON "Brand preference of mobile phones" Dissertation Report Submitted to Amity University In partial fulfillment for the award of Degree of Bachelor of Business Administration Under the guidance of Mrs - Brand Prefference of Mobile Phones introduction.
Anitha Suresh By SABITH.
Research Proposal on Brand Loyalty in Mobile Phone Market. I. Introduction 1. Problem Statement A number of papers have discussed about the factors that influence a consumer's brand loyalty, such as "An empirical model for brand loyalty measurement" (Punniyamoorthy, M and Prasanna Mohan Raj, ), or "The relation between Brand Loyalty, Product.
Brand Product management for Mobile Phones. Essay by lijiao, University, Bachelor's, March download word file, 28 pages, Downloaded times.
Keywords Sony, Motorola, You can see its brand at every mobile phone retail shop in Singapore. People keep asking the new model of the mobile phones/5(4). Mobile Phone and Nokia Essay. RE-CONNECTING PEOPLE Intro Nokia, the Finnish telecommunications company, is not only the world's leading mobile phone manufacturer but also Europe's biggest brand and the world's 5th biggest brand according to the Business Week – Interbrand 'Best Global Brands ' report.
A mobile phone (also known as a cellular phone, cell phone, and a hand phone) is a phone that can make and receive telephone calls over a radio link while moving around a wide geographic area. It does so by connecting to a cellular network provided by a mobile phone operator, allowing access to the public telephone network.Download