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It contains 10 broad sections, including market analysis, management and organization, etc. For the videos themselves, we often see artists leaving off their artist name in the title of the video, which is terrible for search engines.
You need to have a modern and functional site that you can update on your own. We love a tool called Canva for fast and easy banner, graphic and social skin creation. Create a list of tags for each of your marketing plans.
Universal Techniques To make business planning come alive and succeed there are three simple practices that must be always be employed. Kudos to Invoiceberry for figuring out this effective lead-gen tactic too! All resources are free of charge.
Stale, overly promotional, or boring profiles will not help your chances of engaging anyone. Cayenne Consulting — good resource for business entrepreneurs including a start-up valuation calculator, resource directory, and a very popular blog for entrepreneurs.
VFinance is the creator of the massive Venture Capital Directory and has tailored the plan to appeal to funders. These techniques will give you the ammunition you need. Our EPQ support and resources are also of relevance to students undertaking other research projects or qualifications, such as: Moreover though, a solid business plan is a living document that will continue to guide your efforts as your business grows.
Some funders are going to want to see a lot of detail, but you can provide that in appendices. Virtual Business Plan Walk through the design of a business plan.
We also often see description sections left blank too. This is a crucial piece of real estate to tell the viewer what they are watching and provide links to other content you own, such as your website and iTunes, where they can go for more.
This will hurt your promotional efforts as music industry professionals, music bloggers, and fans will visit your socials to see what kind of existing following you have and how serious you are.
Much of his project was spent designing and researching the right materials — and watching as the costs mounted up. Music Distribution Marketing Plan Digital distribution moves a lot faster than it used to, but you should still choose a distributor.
Even if you have invented the "better mousetrap", you need a superior marketing plan to get results.
There were other initiatives, such as the Enterprise Challenge and the opportunity to be a prefect, that I missed out on. Complete our workshop feedback form.
You will notice, however, that sometimes we include links to these products and services in the articles. The channel for The Flaming Lips is a great example of these practices put to use.
I caution you to be selective about what you cross-post to socials.
Josh Heath, who has also done an EPQ, says: Without it you may never reach your destination.Tutors and assessors of the Extended Project Qualification can download useful resources from The University of Manchester.
for example, a dissertation, performance or field study. Although this session is aimed at students undertaking the dissertation project (5, words), it will be useful for all types of project, as the same principles. Having a clear vision of your company's long-term trajectory is essential to ensuring its success.
5 Steps for Creating a Long-Term Plan for Your Startup Fill it with international and. EPQ Template. Prezi for EPQ extend your interest in a subject topic covered in lessons link to the course you are wanting to do at university examples how have techniques in investigating crime scenes changed in the UK and removing preconceptions of TV drama shows How have adaptations of three different species allowed them to survive the.
Build your own business plan in minutes. We're offering FREE business plan templates to help you automate the process and focus on the parts that count, not the formatting and copy-pasting.
Used and trusted by over organizations! Research and development is more important to some companies than to others. For example, a computer software company would spend much more on R&D than a retail sales company would.
Technology companies survive by developing more effective technology than their competitors. In your marketing plan, be as specific as possible; give statistics & numbers and sources. The marketing plan will be the basis, later on, of the all-important sales projection.Download


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- North America
- United States
- Maine
- Taylor-Barry House
- Search
Traveling Luck for Taylor-Barry House Maine, United States
The timezone in Taylor-Barry House is America/Iqaluit
Morning Sunrise at 08:06 and Evening Sunset at 17:06. It's Dark
Rough GPS position Latitude. 43.3861°, Longitude. -70.5328°
Morning Sunrise at 08:06 and Evening Sunset at 17:06. It's Dark
Rough GPS position Latitude. 43.3861°, Longitude. -70.5328°
Weather near Taylor-Barry House Last report from Portland, Portland International Jetport, ME 40.1km awayTemperature: -8°C / 18°F
Wind: 9.2km/h North/Northwest
Cloud: Sky Clear
Satellite map of Taylor-Barry House and it's surroudings...
Geographic features & Photographs around Taylor-Barry House in Maine, United States
church a building for public Christian worship.
- Christ Church (0.5km)
- Saint Andrews Presbyterian Church (0.5km)
- First Parish Unitarian Church (0.6km)
- Kennebunk Baptist Church (0.7km)
- Saint Monicas Catholic Church (0.9km)
- Holy Cross Lutheran Church (1.1km)
- Advent Christian Church (3km)
- Saint Davids Episcopal Church (4km)
- Messiah Christian Church (4.7km)
- West Kennebunkport United Methodist Church (5.2km)
building(s) a structure built for permanent use, as a house, factory, etc..
- Taylor-Barry House (0km)
- Kennebunk Town Hall (0.5km)
- Edith Cleaves Barry Library (0.5km)
- Brick Store Museum (0.5km)
- Kennebunk Free Library (0.6km)
- Storer Mansion (1km)
- Wedding Cake House (1.8km)
- Trolley Museum (5km)
school building(s) where instruction in one or more branches of knowledge takes place.
- Sea Road School (0.9km)
- Middle School of the Kennebunks (2km)
- Kennebunk High School (2.1km)
- Landing School (2.8km)
- Kennebunk Christian Academy (3km)
- Burnham School (3.8km)
- The School Around Us (4.9km)
- Heartwood School of Art (5.1km)
Local Feature A Nearby feature worthy of being marked on a map..
- First Church of Christ Scientist (0.1km)
- Bibber Memorial Chapel (0.8km)
- Shoppers Village Shopping Center (1.2km)
- Kennebunk Recycling Center (1.4km)
- Interchange 3 (4km)
- Old Road Forks (historical) (4.8km)
Accommodation around Taylor-Barry House
The Kennebunk Inn 45 Main St, Kennebunk
Port Inn Kennebunk, an Ascend Hotel Collection Member 55 York St, Kennebunk
Turnpike Motel 77 Old Alewive Rd, Kennebunk
stream a body of running water moving to a lower level in a channel on land.
- Day Brook (1.5km)
- Fernald Brook (3.1km)
- Ward Brook (4km)
- Arundel Swamp Brook (4.5km)
- Goff Mill Brook (4.7km)
- Duck Brook (5.2km)
park an area, often of forested land, maintained as a place of beauty, or for recreation.
- Parsons Field (0.4km)
- Kennebunk Historic District (0.5km)
- Rotary Park (0.9km)
- Lafayette Park (1km)
- Rogers Park (1.1km)
- Rachel Carson National Wildlife Refuge (4.8km)
populated place a city, town, village, or other agglomeration of buildings where people live and work.
- Kennebunk (1.2km)
- Bartlett Mills (1.8km)
- Kennebunk Landing (2.5km)
- Four Corners (4.9km)
- Millers Crossing (4.9km)
cemetery a burial place or ground.
- Hope Cemetery (1.3km)
- Evergreen Cemetery (3.1km)
- Home Cemetery (4.9km)
swamp a wetland dominated by tree vegetation.
- Arundel Swamp (3.3km)
- Punky Swamp (3.6km)
bridge a structure erected across an obstacle such as a stream, road, etc., in order to carry roads, railroads, and pedestrians across.
- Bartletts Bridge (2.3km)
- Durrell Bridge (2.7km)
airport a place where aircraft regularly land and take off, with runways, navigational aids, and major facilities for the commercial handling of passengers and cargo.
- Kennebunk Airport (3.6km)
administrative division an administrative division of a country, undifferentiated as to administrative level.
- Kennebunk, Town of (4.3km)
hospital a building in which sick or injured, especially those confined to bed, are medically treated.
post office a public building in which mail is received, sorted and distributed.
- Kennebunk Post Office (0.8km)
reservoir(s) an artificial pond or lake.
- Wiggins Pond (1.4km)
Wikipedia entries close to Taylor-Barry House
- Kennebunk (CDP), Maine city o city
- West Kennebunk, Maine city o city
- Kennebunkport (CDP), Maine city o city
- Bush compound city o city
- Goat Island Light tower landmark
- Biddeford city i city
- South Sanford, Maine city o city
- Saco (Maine) city i city
- Alfred, Maine city o city
- Wood Island Light tower landmark
- Old Orchard Beach, Maine city o city
- North Berwick (CDP), Maine city o city
- Sanford, Maine city o city
- Springvale, Maine city o city
- Cape Neddick Light tower landmark
- Cape Neddick, Maine city o city
Airports close to Taylor-Barry HousePortland international jetport(PWM), Portland, Usa (40.1km)
Augusta state(AUG), Augusta, Usa (140.3km)
Laurence g hanscom fld(BED), Bedford, Usa (140.7km)
General edward lawrence logan international(BOS), Boston, Usa (141.8km)


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a0fb6e51_6b4a_4d74_851d_49871ee2557a | 4:06 PM UK time, Wednesday, 11 October
Tamworth distribution centre raises £160 for charity.
Well done to our distribution centre in Tamworth who raised £160 for the Charlie Round Foundation by dressing up as their favourite book characters on World Book Day.
May 16 12:31 PM
May 10 9:41 AM
May 09 11:00 AM
December 21 1:58 PM
November 02 9:43 AM


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Following d&c, what were your first cycles like?
Did AF come at usual time? Heavier/lighter? Length of time?
Did you ovulate immediately after d&c or did AF visit first? Has there been a change to your ovulation date or luteal phase?
It can be all over the place!
I had retained tissue, passed one week after my D&C. I did not Ovulate until day 30, and AF came day 40. It was lighter than normal, and shorter.
The second cycle was also off for me. I ovulated 4 days later than normal and then my AF was heavier and awful!
Cycle 3 and 4 have been back to normal for the most part.
I go my period after 33 days (though spotting started on day 29). I think I ovulated after about 3 weeks but didn't think too much. The flow and pain were kinda comparable like before. I think other than the fact it was off by a few days rest felt the same. This was my first cycle so waiting to move to next stage.
I started spotting 28 days after d&c then it increased to read blood on and off several times each day for a few days following that (I'd have blood in the morning then it would decrease through the day and by the night I would be gone). The blood was very watery and looked liked it was mixed with cm. When I saw my ob for the follow up appointment he said it might not have even been AF and that it could have been an ovulation bleed as most people don't ovulate until 4 weeks after d&c apparently. I'm now cd 14 if I count the first day of red as cd1 but no sign of ovulation yet. I'm so confused.
I got AF exactly 5 weeks after d and c
I don't think i ovulated before AF as I was doing HPTs and still getting BFPs until a week before AF came
Then when I got BFN I started using OPKs-for negatives and then a positive 4 days after BFN
We wanted to try before AF so I was delighted
Then 3 days after positive OPK-AF arrived!!!
So yes it can be all over the place!!
I'm currently on CD9 of first proper cycle after d and c now and waiting for my positive OPK. I usually ovulate on day 11/11 so hoping to get it tomorrow!!!
Good luck!
I got mine 6 weeks after D&C. I don't think I ovulated before it, I was still testing positive on HPTs. That period was shorter than normal. I ovulated normally after that and my next cycle started about the right time (a few days early). It felt like a long wait but all seems well now.
Update from me. Confusion settled. I must have had AF 28 days after d&c. I'm now cd15 and got a positive opk this morning so I'm guessing I'm back on track now. I'm not having any ovulation pain yet which is strange as I normally have very noticeable pain where I often need pain killers and a heat pack to ease.
Glad this thread popped back up because I was about to ask some of these questions. I finally started my period yesterday, 7 weeks to the day after my D&C. I woke up this morning having completely bled through my tampon, and all day I've been soaking the Super-Sized tampons every 30 minutes or less. I feel like I've lost enough blood to need a transfusion, it's crazy! It's also been VERY painful, and I never have painful periods. Luckily I have some Percocet left over from my D&C so am taking that to ease the pain.
Anyone else first period after D&C THIS heavy? I'm assuming it's "normal" but it just doesn't seem right!
I had my d&c on 7/11 and AF appeared on 8/13. It has been so long since I had a period. I had an iud for 3 years ( had no period) had my mirena taken out and immediately got pregnant... My period lasted exactly 5 days. Only the 2nd day was heavy. No cramps. I was excited to see her after so long as that could have been the reason for my miscarriage. I didn't have any progesterone to make the lining thick. I am not sure about ovulation... I figure if I get pregnant then it was just meant to be!


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Beijing: Rather than merely conducting a process focused on clarifying the Line of Actual Control (LAC) as suggested by India, China on Wednesday said that it was in favour of a 'code of conduct' along the border with India, to build trust along the boundary.
During his May 14-16 visit to China, Prime Minister Narendra Modi called for both sides to resume the stalled process of clarifying the LAC to prevent incidents and stand-offs along the more than 3,488 km-long disputed border.
China, for its part, has not been keen on the process, citing wide differences in perceptions as one reason behind the deadlock on LAC clarification following a failed exchange of maps in 2005.
"Our position is we should seek some kind of comprehensive measures, not only one measure to control management of the border and ensure peace and tranquility, say, a code of conduct," said the Chinese Foreign Ministry's Deputy Director General for Asian Affairs, Huang Xilian, who is Beijing's "point man" on India.
In an interaction with a group of visiting Indian media and scholars, Huang called for both sides "to try and reach agreement on a code of conduct" and "seek a comprehensive approach".
Huang also revealed why China was somewhat apprehensive about resuming the clarification process, saying that the earlier attempt involving exchange of maps had only "complicated", rather than helped resolve, differences.
Recently India has witnessed several incursion by the Red army across the border. Tension is also brewing with Chinese expansionist activities in the South China sea.


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I teach English as a foreign language for a private company in Shanghai, China. I'm in a unique situation in my classes. I don't have the luxury of a semester with my students. In fact, I may have one class with them and never see them again.
Considering our system against the Seven Principles, it seems we fall way short on the majority of them.
1. Frequent student-teacher contact
In each class session, we practice speaking English in a different real-life situation. The lessons are self-contained so that students can come and go as it suits them. We have hundreds of teachers and hundreds of thousands of students, so building a lasting rapport between teacher and student is not likely.
2. Cooperation among students
We offer online conversation classes in which students interact with each other on a given topic for 45 minutes at a time. It works well for people who have an erratic schedule, busy executives who can attend only infrequently, and college students who have a lot of time on their hands. However, there is no lasting collaboration among the students.
3. Active learning
Though we do try to encourage active participation in the lessons, students spend a lot of passive time in the classrooms, waiting for their turn to speak. In the online classroom, we are limited by the software, so only one student can talk at a time, making group work and discovery learning impossible.
4. Prompt feedback
Student receive feedback on grammar mistakes or vocabulary words during the 45-minute classes, but after the class is finished, they have no opportunity to delve deeper into the issues with a teacher. That makes for a more autonomous learner!
5. Time on task
Since each class is self-contained and the students are free to come and go at will, teachers have no control over how much time a students spends practicing. Our website monitors how much time students spend there, but teachers are unaware of the details.
6. High expectations
There is no "performance" element to our classes. We discuss a topic, but there is no encouragement to publish thoughts or reactions to a blog or other public medium. Students have nothing to show for their 45-minute effort.
7. Respect diverse talents
Although our students come into a classroom from all over the world, the lessons are presented in a fixed style, each similar to the last. If the student doesn't learn that way, they just don't come to class.
Looks like we need to do some major rethinking about our online and face to face classes!


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Read Full Review
Full Review
The Mac vs. PC debate may have cooled considerably with Microsoft focusing on its hybrid hardware, but that hasn't slowed the progression of Cupertino's top-of-the-line laptops. The 2014 line of MacBook Pros are lighter, smaller, faster, and more powerful than ever before. And if you are willing to pay for the best of the best, Apple's top offering is truly a sight to behold.
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See Full Specifications
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The door hasn't entirely closed yet on one of North America's most beloved retailers – but there's officially but one single foot keeping it open.
Yesterday (Sunday) marked the closure of Blockbuster Video's final two locations in Alaska…traditionally a 'hot' spot for the retailer thanks to crazy long winters and slow WiFi. That means if you want a shot of nostalgia and long to visit the only remaining Blockbuster Video, your road trip won't exactly be a long one, at least not from our home here in B.C…
'Cause the last Blockbuster in existence is in Bend, Oregon.
Sandi Harding is the general manager of the Bend location, and good news for die-hard's….she says they don't plan to go anywhere, anytime soon. She told CNN that, in addition to older titles on the shelves, she wakes up early every Tuesday morning and personally purchases the newest titles to stock the shelves.
Just looking at the picture of rows & rows of DVD's brings back a ton of memories; Friday nights, racing to our Vernon location, hoping to nab the final copy of the hottest flick before someone else got their mitts on it. Sigggghhhh.
Are you sad that Blockbuster is now oh-so-close to its final bow? Or did Netflix make this day inevitable? ~ Jason


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Paul Kelly - Life Is Fine (Vinyl LP)
Availability: In Stock
Paul Kelly - Life Is Fine (Vinyl LP)
Paul Kelly lifts the electric guitar out of the case again and unveils one of the most powerful albums of his career with Life Is Fine. Engineered and co-produced by Steve Schram, the album is preceded by the rock-flavored lead single "Firewood and Candles," a rollicking track reminiscent of his finest ŌĆś80s recordings, a feeling which permeates the entire collection. Life Is Fine features a similar cast of players to that of 2014's Merri Soul Sessions. Vika and Linda Bull are on vocals, Ashley Naylor on guitar, Bill McDonald on bass, Cameron Bruce on keys and Peter Luscombe on drums. Fans of one of our greatest songwriters can be sure - Life Is Fine is one of Kelly's strongest and most evocative albums, another treasure to sit proudly on the shelf beside any of his earlier classics.
- Rising Moon
- Finally Something Good
- Firewood and Candles
- My Man's Got A Cold
- Rock Out On the Sea
- Leah: The Sequel
- Letter in the Rain
- Josephina
- Don't Explain
- I Smell Trouble
- Petrichor
- Life Is Fine
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About kyle_xy
Profile Information
Application Season
2018 Fall
Civil Engineering, MSc
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kyle_xy started following Civil & Environmental Engineering - Fall 2018 Applicants, Funding at York University, Toronto, Tight Deadline to Accept Offer from 3rd Choice Program and and 3 others
Funding at York University, Toronto
kyle_xy replied to Nickybert's topic in The BankI received a fully funded acceptance from York. They have this graduate funding model that covers tuition and at least part of living expenses.
Tight Deadline to Accept Offer from 3rd Choice Program
kyle_xy posted a topic in Decisions, DecisionsHi guys, I received a fully funded admission offer from a Canadian University (let's call it school C). I was very excited about it until I realized I only have till 2nd March to respond to the offer. This is the only University I have heard from so far and I am eager to hear from the others, especially my top 2 choices (schs A and B). I believe I have a reasonable chance of getting a funded admit from at least one of my top 2 programs and I really, really want to hear from them before deciding to accept any offer. However, it is quite unlikely that either of those schools will make a decision before 2nd March. School C's program is quite new and not very well reputed yet (the 1st batch of their undergraduate students will graduate this year). So I believe given the choice, I will be better off at either A or B. They are my dream schools and I really love them (hint: one of them is the absolute best in Canada). I had contacted my POI at sch C before applying and he has been very supportive so far. By the time I received the admit offer, we had exchanged almost 20 emails. A week before I received the official admit offer, the POI informed me that I had been approved and that after I receive the admission offer, I should contact him directly if I have any questions about it. Guys, what do you think I should do? Should I contact my POI and ask for an extension? How do I even ask for that, without making it look like I don't want to accept the offer? Because if A and B is off the table, I will be perfectly happy to accept C. Will it be wise to contact A and B about the situation? What will I do if the extension is not granted?
strawberrykat reacted to a post in a topic: Civil & Environmental Engineering - Fall 2018 Applicants
Civil & Environmental Engineering - Fall 2018 Applicants
kyle_xy replied to strawberrykat's topic in EngineeringMasters applicant here. I applied to a mix of US and Canadian schools - Purdue, UW, ASU, U of Toronto, UBC, York University. I have already received an unofficial acceptance from York.
Fall 2018 Admission
kyle_xy replied to PhD_hopeful_'s topic in Waiting it OutI also received a similar email from my POI on Thursday.
York University Toronto - MASc Civil Engineering FALL 17
kyle_xy replied to freitashian's topic in EngineeringHi, I know I'm a year late, but did you eventually get an admit? I also applied for Fall 2018 semester. I'm waiting for a decision to be made


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Trevor Donovan Films 'Wolf Hound'- See Exclusive Pics From the Set!
Trevor Donovan is filming his new movie Wolf Hound, and Just Jared has exclusive pictures from the set!
In the upcoming movie, Trevor plays Major Erich Roth, an ACE pilot for Germany during World War II.
"The movie is going amazing. Dressing like a Nazi soldier is….different, but playing a bad guy is fun as hell," Trevor tells Just Jared of filming the movie.
Trevor's real-life grandfather served in the U.S. Navy during World War II, along with his uncle Cedrick, who was in the Army and received two Purple Hearts.
Wolf Hound is inspired by the real-life plot designed to fly Allied aircraft as Trojan horses deep behind enemy lines. The action takes place in 1944 as a fighter pilot escorts a B-17 bomber into Nazi territory, engages in a one-on-one aerial joust with a Nazi ace pilot, destroying both of their planes and forcing them to bail out and parachute to the forest floor below. Alone, outnumbered, and being hunted down by a Nazi convoy hot on his trail, he must face his vengeful nemesis in a deadly game of cat and mouse to survive.
The film also co-stars James Maslow, Michael Wayne Foster and John Wells.
See pictures from the set below!


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Chiara Boni
NYFW Spring/Summer 2017
See below for step-by-step tutorial
50's Inspired Big, Fluffy, High-Volume Hair
Step-by-Step Tutorial
Hair Stylist: Jon Reyman
Olivia Garden Hair Tools:
HeatPro Thermal Brush, Ceramic + Ion Supreme Combo Paddle Brush,
& Style-Up Folding Combo Teasing Brush
Step 1: Start by using the styling product on dry hair and then blow dry it with the HeatPro Thermal Round Brush 1 3/4" to add big volume from the root, working section by section.
Step 2: Next, curl the entire head from root to ends with a 3/4" flat barrel curling iron, leaving the curls tight and untouched while spritzing hairspray periodically to hold the spiral.
Step 3: Once the whole head is curled, brush curls out using the Ceramic + Ion Supreme Combo Paddle Brush, leaving soft waves.
Step 4: Finally, pump up the volume and create dramatic dimension by using the Style-Up Folding Combo Teasing Brush to backcomb each curl, starting from the root and working down to the ends, leaving body of the waves intact.
Step 5: For longer hair, pin up long stands into the back of the head creating a faux bob effect. Finish with hairspray for strong hold.


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Effect of fenofibrate on the need for laser treatment for diabetic retinopathy (FIELD study): a randomised controlled trial
Year published
MetadataShow full item record
Background: Laser treatment for diabetic retinopathy is often associated with visual fi eld reduction and other ocular side-eff ects. Our aim was to assess whether long-term lipid-lowering therapy with fenofi brate could reduce the progression of retinopathy and the need for laser treatment in patients with type 2 diabetes mellitus. Methods: The Fenofi brate Intervention and Event Lowering in Diabetes (FIELD) study was a multinational randomised trial of 9795 patients aged 50-75 years with type 2 diabetes mellitus. Eligible patients were randomly assigned to receive fenofi brate 200 mg/day (n=4895) or matching placebo (n=4900). At each clinic visit, information concerning laser treatment for diabetic retinopathy-a prespecifi ed tertiary endpoint of the main study-was gathered. Adjudication by ophthalmologists masked to treatment allocation defi ned instances of laser treatment for macular oedema, proliferative retinopathy, or other eye conditions. In a substudy of 1012 patients, standardised retinal photography was done and photographs graded with Early Treatment Diabetic Retinopathy Study (ETDRS) criteria to determine the cumulative incidence of diabetic retinopathy and its component lesions. Analyses were by intention to treat. This study is registered as an International Standard Randomised Controlled Trial, number ISRCTN64783481. Findings: Laser treatment was needed more frequently in participants with poorer glycaemic or blood pressure control than in those with good control of these factors, and in those with a greater burden of clinical microvascular disease, but the need for such treatment was not aff ected by plasma lipid concentrations. The requirement for fi rst laser treatment for all retinopathy was signifi cantly lower in the fenofi brate group than in the placebo group (164 [3紥] patients on fenofi brate vs 238 [4繥] on placebo; hazard ratio [HR] 0綹, 95% CI 0絶-0縴; p=0簰02; absolute risk reduction 1絥 [0緭2糝). In the ophthalmology substudy, the primary endpoint of 2-step progression of retinopathy grade did not diff er signifi cantly between the two groups overall (46 [9綥] patients on fenofi brate vs 57 [12糥] on placebo; p=0籹) or in the subset of patients without pre-existing retinopathy (43 [11紥] vs 43 [11緥]; p=0縷). By contrast, in patients with pre-existing retinopathy, signifi cantly fewer patients on fenofi brate had a 2-step progression than did those on placebo (three [3籥] patients vs 14 [14綥]; p=0簰4). An exploratory composite endpoint of 2-step progression of retinopathy grade, macular oedema, or laser treatments was signifi cantly lower in the fenofi brate group than in the placebo group (HR 0綶, 95% CI 0紷-0繴; p=0簲2). Interpretation: Treatment with fenofi brate in individuals with type 2 diabetes mellitus reduces the need for laser treatment for diabetic retinopathy, although the mechanism of this eff ect does not seem to be related to plasma concentrations of lipids.
Journal Title
The Lancet


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The World Cup Thrives on Attack
Aggressive Bowling Key to Cricket World Cup
So far this has been a cricket World Cup of unfettered aggression.
That's been at its most obvious in the batting: In 33 completed games, there have been 23 team scores of 300-plus and 26 individual centuries.
But with all the usual factors—big bats, small boundaries, Twenty20-juiced techniques and only four fielders outside the inner ring—taking...


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Hello, I'm handling with an oVirt bug, about a race condition during parallel registering hosts: http://gerrit.ovirt.org/#/c/5338/
Message: The vds_spm_id from vds_spm_map table is filled with a code select/increment/insert. Registering many hosts at same time causes a race condition. More than one java thread comes up with the same value for selectedId, since that's just being derived from knowledge about the set of vds_spm_id_map entries already in the database. This patch change the way to obtain the vds_spm_id to be through a database sequence. The reviewer wrote: "... Each pool can have max vds_spm_id equals to 255. So, by using sequence count the problem of parallel registration will be solved, but a number of vdsms at pool will be reduced. ..." Mailing him for details, he added: "a limitation is coming from side of vdsm, if I am correct it is because of using SAN lock, so they just can not accept spm id which is higher than 255." Trying to reproduce the vdsm limitation, no problem was found: engine=# select * from vds_spm_id_map; storage_pool_id | vds_spm_id | vds_id --------------------------------------+------------+-------------------------------------- e32f1e2a-b5bb-11e1-9431-52540038c4e1 | 259 | 13bbf86e-c5da-11e1-a73c-52540038c4e1 My host added with vds_spm_id = 259 is fully functional, with some storage pools attached and so forth. Since I'm not able to reproduce, I'd like to ask you guys if someone could point me to the right direction to reproducing - or clarify where is the mentioned limit. Best, -- Pahim _______________________________________________ vdsm-devel mailing list email@example.com https://fedorahosted.org/mailman/listinfo/vdsm-devel


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Not known Factual Statements About Organifi review
In the listing of components with their Positive aspects described, it is fairly very clear this mega nourishment superfood drink has pretty potent antioxidant Qualities. Toxins, at the time gathered within our bodies can manifest themselves as pores and skin blemishes or rashes.
We can easily't allow for resale of Organifi merchandise, so empty bottles will likely be refunded only immediately after sufficient time has handed for one shopper to consume Organifi as directed.
I do take pleasure in Organifi Practically each day either in smoothies or in the glass of water for the final three months. It took me a handful of periods to acquire the flavor, but now I think it preferences good.
Weight reduction is an additional benefit that comes with using this green juice. You will find a good variety of people who are combating weight. A large number of individuals are unable to afford to pay for consuming healthier due to the fact wholesome foods are pretty costly.
These statements haven't been accredited from the Foodstuff and Drug Administration. This item is just not meant to diagnose, deal with, heal, or stop any condition. Testimonials located at Organifi.com and/or from FITLIFETV LLC are unverified results that have been forwarded to us by end users in the Juice With Drew application, and should not mirror The standard purchaser's experience, might not implement to the standard man or woman and so are not intended to represent or guarantee that anybody will attain exactly the same or similar final results." Search
Chlorella improves cardiovascular overall health, provides help for typical hormonal functionality and lowers blood pressure level as well as unhealthy cholesterol. Furthermore, this ingredient is beneficial to most cancers patients as it helps to waylay the consequences of chemotherapy and radiation. Performing to be a detoxifier, In addition, it contributes in flushing out the toxins inside our bodies the moment taken.
Using browse around here this type of juice, you boost the quantity of nutrients and water you're taking into the body. This enables you to do away with toxins through urination many occasions per day.
Organifi is a protein powder that features Those people sought-right after full foodstuff vitamins and in some cases has digestive enzymes.
It isn't simple to get this organifi juice in neighborhood stores. When you are considering getting this product or service, your very best wager could well be buying it on the internet. The ideal spot to obtain Organifi Environmentally friendly Juice is on its official Web-site.
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Most of us have heard about inexperienced juice: it's the juice you make by blending, grinding, and juicing eco-friendly veggies.
Should you be applying Organifi environmentally friendly drink powder being a weightloss nutritional supplement, you may find yourself selecting to employ it instead of a food or two every day.
Go to your wellbeing food items retailer and ask for the Ashwagandha root tea. A fifty percent pound of tea is beneath $10. Lookup all the key benefits of this tea and you'll see that it combats each and every menopause symptom. Hope this will help
You can purchase the Organifi Entire Protein from their official Internet site. Just about every bottle is around $80 (moreover shipping and managing) for 1 months' value with the product. If you buy multiple bottles, you will get a reduction on the worth.


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Kingsland Road Post Office, London is categorised as 'Retailers - other' and is located in London. It currently has a food hygiene rating of 'Exempt' from Hackney Food Safety.
Retailers - other
416 Kingsland Road
We'd love to hear what you have to say about this eating establishment. You can share your photos, too - just click on the "upload images" icon that appears when you activate the message box.


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A Review Of cheap internet plans
Jen June 26, 2012 at six:fifty seven pm Reply I switched to AT&T Uverse and had the service for around 2 weeks. Within just that 2 7 days interval, I needed to have the DVR changed two times as it dropped ALL of my recorded displays. Was pretty glad I had held off on cancelling Comcast right up until I had been sure I'd be proud of Uverse. When Uverse is Doing work, it is great. It is way exceptional to Comcast DVR so far as perform. Photo high quality not as terrific as Comcast, but I could Dwell with it.
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InSinkErator H-HOT100 Invite Instant Hot Water Dispenser with 1-Year In-Home Warranty - Tank Included - n/a
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Return Policy
You can initiate a return for most new and unopened items within 30 days of delivery, please see Final Sales Exclusions for exceptions. You are responsible for general return shipping cost; you must return items in new or unused condition with all original materials included with the shipment. We must receive your returned items at our facility within 45 days of delivery. If the return is a result of our error or defective product, a full refund will be issued.
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ReadyHot RH-200-560-BN Instant Hot Water Dispenser with Faucet
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InSinkErator H-HOT150 Invite Instant Hot Water Dispenser, Single Handle Hot Water Only - Tank Included - n/a
Today: $239.00 - $249.00
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Today: $222.99
Product Features:
- Fully covered under InSinkErator's 1-year in-home service warranty
- For use in hot water applications only
- Self-closing valve cartridge
- Premier finishing process - resistant to corrosion and tarnishing
- Easy push-button activation
- High-arch spout design provides maximum room under the faucet
- Complete with coordinating water tank - holds 2/3 gallon of near boiling water
- Produces up to 60 cups per hour
- Temperature adjustable from 160° F to 201° F
- All hardware required for dispenser installation is included
Product Specifications:
- Overall Height: 6-1/4" (measured from counter top to highest point on faucet)
- Spout Reach: 5-3/8" (measured from center of faucet body to center of spout outlet)
- Maximum Deck Thickness: 3"
- Faucet Hole Size: 1-1/4" - 1-1/2"
- Capacity: 60 cups-per-hour
- Voltage: 115 V
- Wattage: 750 W
- Amperage: 6.25 amps
While we aim to supply accurate product information, it is sourced by manufacturers, suppliers and marketplace sellers, and has not been provided by Overstock.
|Faucet Style
|Hot Water Dispenser
|Number of Faucet Handle
|Single Handle
|Number of Faucet Installation Hole
|Single hole
|Faucet Mount Style
|Deck Mount
|Flow Rate
|Up to 1 GPM
|6-7 Inches
|Country of Origin
|United States
Nice to have the tank come with the faucet. Disappointed to find out that all of the filters that are shown with these devices when they are positioned for sale are "extra" and not included in the base price. I got the "HOT" only model. Not sure if the "HOT/COLD" has a refrigerator for the water or just tap temperature, so I saved the bucks and got the hot only for less that 1/2 the price of the Hot and Cold - which looks like Hot and tap temp.
I purchased the hot water dispenser approximately a year now and I couldn't be happier. It was a great addition to our kitchen, we use daily!
This user was entered into a sweepstakes after submitting their honest review.
It couldn't be more convenient to have hot water always at your fingertip. The temperature for the perfect cup of tea. I love it!
Love this. Set your water temp from 165° to 210°. Just Remember not to stick your hand in it. Wish the facet would move side to side.
I received this by UPS via Overstock.com the other day and I did not order it. I have been waiting for an RMA from Build .com where it came from for 3 days. They said it could take up to 3 to 5 days before I received the RMA via Email. I think this is a poor way to do business and would avoid this company if at all possible.
Arrived super fast and was everything I expected it to be
Questions & Answers
I have always had an InSinkErator Hot water heater and have always loved the convenience of it. It's a great product.
Shopping Tips & Inspiration
Advantages of Owning a Pot Filler Faucet
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Winterize Your Home Checklist
Late fall is the best time to winterize your home. Cozy blankets and hot drinks help, but insulating your home early can cut energy spending and keep you warm all winter. Vulnerable areas like windows, doors, and plumbing can leak heat, leaving you chilly all season. With a little maintenance, you can keep the warm air in and Jack Frost out. Follow this checklist to winterize your home, save money, and stay cozy.
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Sold and Shipped by Build, An Overstock Marketplace Seller
Build on Overstock offers products for all your home improvement needs including plumbing, HVAC, lighting, door hardware, flooring, tools, appliances, power equipment and home décor. If you have questions about a hard-to-find product, our friendly and knowledgeable customer service representatives are here to help. They can be reached at 1-866-709-3857.
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Items must be returned in new or unused condition and contain all original materials included with the shipment. For the return policy on a Marketplace item, please refer to the Seller's individual policy, located on the product page by clicking on the Seller name. More Details
FINAL SALE EXCLUSION: Items marked as FINAL SALE are not returnable unless the problem you experience is the result of our error.
For your protection, all orders are screened for security purposes. If your order is selected for review, our Loss Prevention Team may contact you by phone or email. There may be a two business day delay to process your order.
** Most Oversize orders are delivered within 1-4 weeks. Some orders may take 6 weeks to be delivered.


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Anti-ATM (phospho S1981) antibody [10H11] (ab19304)
- Datasheet
- References
- Protocols
Product nameAnti-ATM (phospho S1981) antibody [10H11]
See all ATM primary antibodies
DescriptionMouse monoclonal [10H11] to ATM (phospho S1981)
Host speciesMouse
Tested applicationsSuitable for: WB, IP, ICC/IFmore details
Species reactivityReacts with: Human
Synthetic peptide: SLAFEESpQSTTISS, corresponding to amino acids 1974-1988 of Human ATM Kinase.
Positive control
- This antibody detects the phospho-ATM kinase in human samples.
Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Storage bufferPreservative: 0.05% Sodium azide
Constituents: 99% PBS, 0.1% BSA
Concentration information loading...
PurityImmunogen affinity purified
Clone number10H11
Research areas
Associated products
Compatible Secondaries
Isotype control
Our Abpromise guarantee covers the use of ab19304 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|1/500 - 1/1000. Detects a band of approximately 370 kDa.
|Use at an assay dependent concentration.
|1/50 - 1/1000.
FunctionSerine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]-Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and monospecific recognition by the B-cell antigen receptor (BCR) expressed on individual B lymphocytes. After the introduction of DNA breaks by the RAG complex on one immunoglobulin allele, acts by mediating a repositioning of the second allele to pericentromeric heterochromatin, preventing accessibility to the RAG complex and recombination of the second allele. Also involved in signal transduction and cell cycle control. May function as a tumor suppressor. Necessary for activation of ABL1 and SAPK. Phosphorylates p53/TP53, FANCD2, NFKBIA, BRCA1, CTIP, nibrin (NBN), TERF1, RAD9 and DCLRE1C. May play a role in vesicle and/or protein transport. Could play a role in T-cell development, gonad and neurological function. Plays a role in replication-dependent histone mRNA degradation. Binds DNA ends.
Tissue specificityFound in pancreas, kidney, skeletal muscle, liver, lung, placenta, brain, heart, spleen, thymus, testis, ovary, small intestine, colon and leukocytes.
Involvement in diseaseDefects in ATM are the cause of ataxia telangiectasia (AT) [MIM:208900]; also known as Louis-Bar syndrome, which includes four complementation groups: A, C, D and E. This rare recessive disorder is characterized by progressive cerebellar ataxia, dilation of the blood vessels in the conjunctiva and eyeballs, immunodeficiency, growth retardation and sexual immaturity. AT patients have a strong predisposition to cancer; about 30% of patients develop tumors, particularly lymphomas and leukemias. Cells from affected individuals are highly sensitive to damage by ionizing radiation and resistant to inhibition of DNA synthesis following irradiation.
Note=Defects in ATM contribute to T-cell acute lymphoblastic leukemia (TALL) and T-prolymphocytic leukemia (TPLL). TPLL is characterized by a high white blood cell count, with a predominance of prolymphocytes, marked splenomegaly, lymphadenopathy, skin lesions and serous effusion. The clinical course is highly aggressive, with poor response to chemotherapy and short survival time. TPLL occurs both in adults as a sporadic disease and in younger AT patients.
Note=Defects in ATM contribute to B-cell non-Hodgkin lymphomas (BNHL), including mantle cell lymphoma (MCL).
Note=Defects in ATM contribute to B-cell chronic lymphocytic leukemia (BCLL). BCLL is the commonest form of leukemia in the elderly. It is characterized by the accumulation of mature CD5+ B lymphocytes, lymphadenopathy, immunodeficiency and bone marrow failure.
Sequence similaritiesBelongs to the PI3/PI4-kinase family. ATM subfamily.
Contains 1 FAT domain.
Contains 1 FATC domain.
Contains 1 PI3K/PI4K domain.
DomainThe FATC domain is required for interaction with KAT5.
modificationsPhosphorylated by NUAK1/ARK5. Autophosphorylation on Ser-367, Ser-1893, Ser-1981 correlates with DNA damage-mediated activation of the kinase.
Acetylation, on DNA damage, is required for activation of the kinase activity, dimer-monomer transition, and subsequent autophosphorylation on Ser-1981. Acetylated in vitro by KAT5/TIP60.
Cellular localizationNucleus. Cytoplasmic vesicle. Primarily nuclear. Found also in endocytic vesicles in association with beta-adaptin.
- Information by UniProt
Database links
- Entrez Gene: 472 Human
- Omim: 607585 Human
- SwissProt: Q13315 Human
- Unigene: 367437 Human
Alternative names
see all
- A-T mutated antibody
- A-T mutated homolog antibody
- AT mutated antibody
Immunofluorescent analysis of ATM phosphorylated on pSer1981 (green) in HeLa cells left untreated (left panels) or treated with 10uM Camptothecin for 4 hours (right panels). Formalin fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 10 minutes at room temperature and blocked with 1% Blocker BSA for 15 minutes at room temperature. Cells were probed with a phospho-ATM (pSer1981) monoclonal antibody (ab19304), at a dilution of 1:1000 for at least 1 hour at room temperature, washed with PBS, and incubated with DyLight 488 goat anti-mouse IgG secondary antibody at a dilution of 1:400 for 30 minutes at room temperature. F-Actin (red) was stained with DyLight 554 Phalloidin (top panels). A merged image with nuclei staining (blue) using Hoechst 33342 dye is shown on bottom panels. Images were taken at 20X magnification.
Immunofluorescent analysis of Phospho-ATM pSer1981 in 293 untreated cells (left panel) or stimulated cells with 100 mJ UV (right panel) . Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes at room temperature and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with a Phospho-ATM pSer1981 Monclonal Antibody (10H11)(ab19304) at a dilution of 1:50 and incubated overnight in a humidified chamber. Cells were washed with PBST and incubated with a DyLight-conjugated secondary antibody for 45 minutes at room temperature in the dark. F-actin (red) was stained with a fluorescent phalloidin and nuclei (blue) were stained with DAPI. Images were taken at a 60X magnification.
By Western blot this antibody detects a ~370 kDa protein representing the phospho-ATM kinase in crude lysates from gamma irradiated HeLa cells. In immunofluorescence procedures, ab19304recognizes the phospho-ATM kinase in irradiated human and mouse fibroblasts.
Datasheets and documents
ab19304 has not yet been referenced specifically in any publications.