text:
House Democrats Take Aim at Bonilla
Continuing the aggressive spending that won them 29 seats on Nov. 7, the Democratic Congressional Campaign Committee is up with television ads in Texas's 23rd District where Rep. Henry Bonilla (R) and former Rep. Ciro Rodriguez (D) will square off in a Dec. 12 runoff.
The DCCC ad, which was produced by GMMB, alleges that Bonilla has "neglected our veterans" by supporting billion of dollars in cuts to veterans' benefits and voting "against extending health care to our National Guard." The ad's narrator says Rodriguez "fights for our returning heroes" and represents the "change we need."
According to independent expenditure reports filed yesterday with the Federal Election Commission, the DCCC is spending $154,000 to run the commercials. The National Republican Congressional Committee is not currently on the air in the district.
Even with the DCCC's investment, a win in this district looks like a long shot. Redrawn this summer following a June ruling by the U.S. Supreme Court that a 2003 re-redistricting plan violated the Voting Rights Act, the massive south Texas 23rd District is now 61 percent Hispanic -- up from 51 percent under the previous lines. According to the Texas Legislative Council, Republican candidates running for statewide office in 2004 won an average of 53 percent of the vote in that areas that make up what is now the 23rd District, while Democrats took 47 percent.
Bonilla won just 49 percent of the vote on Nov. 7 -- missing the chance to avoid a runoff by a single point. Rodriguez, who represented a neighboring district from 1996 until 2004, received just 20 percent. All told, Bonilla won 60,147 votes to Rodriguez's 24,593 -- a daunting margin for the Democrat to make up in five weeks.
Bonilla also carries a massive financial edge over Rodriguez. In financial reports covering contributions and expenditures through Oct. 18, Bonilla showed nearly $2 million in the bank compared with just $23,000 for Rodriguez. The DCCC can make up some of that fundraising deficit, but not all of it.
The 23rd District is one of only a handful House races not yet decided. The others are Louisiana'S 2nd District, where state Rep. Karen Carter (D) is trying to unseat Rep. William Jefferson (D) in a Dec. 9 runoff; Ohio's 15th District, where the contest between Rep. Deborah Pryce (R) and Franklin County Commissioner Mary Jo Kilroy (D) has gone to a recount; and Florida's 13th District, where banker Christine Jennings (D) is contesting the results of her narrow loss to automobile dealer Vern Buchanan (R).
Campaign Web sites:
Chris Cillizza
November 30, 2006; 5:30 PM ET
Categories: House
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Posted by: Andrus | December 30, 2006 7:08 AM | Report abuse
I'll tell you what they should be taking aim at: Bush and Cheney and the underlying "rationale" behind the so-called "war on terror". Let's take a few moments and look at some of the details of the horrible event that precipitated the "war on terror" and around which America's foreign policy has been inextricably wrapped ever since.
One thing that struck me as odd in the days after 9/11 was Bush saying "We will not tolerate conspiracy theories [regarding 9/11]". Sure enough there have been some wacky conspiracy theories surrounding the events of that day. The most far-fetched and patently ridiculous one that I've ever heard goes like this: Nineteen hijackers who claimed to be devout Muslims but yet were so un-Muslim as to be getting drunk all the time, doing cocaine and frequenting strip clubs decided to hijack four airliners and fly them into buildings in the northeastern U.S., the area of the country that is the most thick with fighter bases. After leaving a Koran on a barstool at a strip bar after getting drunk on the night before, then writing a suicide note/inspirational letter that sounded like it was written by someone with next to no knowledge of Islam, they went to bed and got up the next morning hung over and carried out their devious plan. Nevermind the fact that of the four "pilots" among them there was not a one that could handle a Cessna or a Piper Cub let alone fly a jumbo jet, and the one assigned the most difficult task of all, Hani Hanjour, was so laughably incompetent that he was the worst fake "pilot" of the bunch, with someone who was there when he was attempting to fly a small airplane saying that Hanjour was so clumsy that he was unsure if he had driven a car before. Nevermind the fact that they received very rudimentary flight training at Pensacola Naval Air Station, making them more likely to have been C.I.A. assets than Islamic fundamentalist terrorists. So on to the airports after Mohammed Atta supposedly leaves two rental cars at two impossibly far-removed locations. So they hijack all four airliners and at this time passengers on United 93 start making a bunch of cell phone calls from 35,000 feet in the air to tell people what was going on. Nevermind the fact that cell phones wouldn't work very well above 4,000 feet, and wouldn't work at ALL above 8,000 feet. But the conspiracy theorists won't let that fact get in the way of a good fantasy. That is one of the little things you "aren't supposed to think about". Nevermind that one of the callers called his mom and said his first and last name ("Hi mom, this is Mark Bingham"), more like he was reading from a list than calling his own mom. Anyway, when these airliners each deviated from their flight plan and didn't respond to ground control, NORAD would any other time have followed standard operating procedure (and did NOT have to be told by F.A.A. that there were hijackings because they were watching the same events unfold on their own radar) which means fighter jets would be scrambled from the nearest base where they were available on standby within a few minutes, just like every other time when airliners stray off course. But of course on 9/11 this didn't happen, not even close. Somehow these "hijackers" must have used magical powers to cause NORAD to stand down, as ridiculous as this sounds because total inaction from the most high-tech and professional Air Force in the world would be necessary to carry out their tasks. So on the most important day in its history the Air Force was totally worthless. Then they had to make one of the airliners look like a smaller plane, because unknown to them the Naudet brothers had a videocamera to capture the only known footage of the North Tower crash, and this footage shows something that is not at all like a jumbo jet, but didn't have to bother with the South Tower jet disguising itself because that was the one we were "supposed to see". Anyway, as for the Pentagon they had to have Hani Hanjour fly his airliner like it was a fighter plane, making a high G-force corkscrew turn that no real airliner can do, in making its descent to strike the Pentagon. But these "hijackers" wanted to make sure Rumsfeld survived so they went out of their way to hit the farthest point in the building from where Rumsfeld and the top brass are located. And this worked out rather well for the military personnel in the Pentagon, since the side that was hit was the part that was under renovation at the time with few military personnel present compared to construction workers. Still more fortuitous for the Pentagon, the side that was hit had just before 9/11 been structurally reinforced to prevent a large fire there from spreading elsewhere in the building. Awful nice of them to pick that part to hit, huh? Then the airliner vaporized itself into nothing but tiny unidentifiable pieces most no bigger than a fist, unlike the crash of a real airliner when you will be able to see at least some identifiable parts, like crumpled wings, broken tail section etc. Why, Hani Hanjour the terrible pilot flew that airliner so good that even though he hit the Pentagon on the ground floor the engines didn't even drag the ground!! Imagine that!! Though the airliner vaporized itself on impact it only made a tiny 16 foot hole in the building. Amazing. Meanwhile, though the planes hitting the Twin Towers caused fires small enough for the firefighters to be heard on their radios saying "We just need 2 hoses and we can knock this fire down" attesting to the small size of it, somehow they must have used magical powers from beyond the grave to make this morph into a raging inferno capable of making the steel on all forty-seven main support columns (not to mention the over 100 smaller support columns) soften and buckle, then all fail at once. Hmmm. Then still more magic was used to make the building totally defy physics as well as common sense in having the uppermost floors pass through the remainder of the building as quickly, meaning as effortlessly, as falling through air, a feat that without magic could only be done with explosives. Then exactly 30 minutes later the North Tower collapses in precisely the same freefall physics-defying manner. Incredible. Not to mention the fact that both collapsed at a uniform rate too, not slowing down, which also defies physics because as the uppermost floors crash into and through each successive floor beneath them they would shed more and more energy each time, thus slowing itself down. Common sense tells you this is not possible without either the hijackers' magical powers or explosives. To emphasize their telekinetic prowess, later in the day they made a third building, WTC # 7, collapse also at freefall rate though no plane or any major debris hit it. Amazing guys these magical hijackers. But we know it had to be "Muslim hijackers" the conspiracy theorist will tell you because (now don't laugh) one of their passports was "found" a couple days later near Ground Zero, miraculously "surviving" the fire that we were told incinerated planes, passengers and black boxes, and also "survived" the collapse of the building it was in. When common sense tells you if that were true then they should start making buildings and airliners out of heavy paper and plastic so as to be "indestructable" like that magic passport. The hijackers even used their magical powers to bring at least seven of their number back to life, to appear at american embassies outraged at being blamed for 9/11!! BBC reported on that and it is still online. Nevertheless, they also used magical powers to make the american government look like it was covering something up in the aftermath of this, what with the hasty removal of the steel debris and having it driven to ports in trucks with GPS locators on them, to be shipped overseas to China and India to be melted down. When common sense again tells you that this is paradoxical in that if the steel was so unimportant that they didn't bother saving some for analysis but so important as to require GPS locators on the trucks with one driver losing his job because he stopped to get lunch. Hmmmm. Further making themselves look guilty, the Bush administration steadfastly refused for over a year to allow a commission to investigate 9/11 to even be formed, only agreeing to it on the conditions that they get to dictate its scope, meaning it was based on the false pretense of the "official story" being true with no other alternatives allowed to be considered, handpicked all its members making sure the ones picked had vested interests in the truth remaining buried, and with Bush and Cheney only "testifying" together, only for an hour, behind closed doors, with their attorneys present and with their "testimonies" not being recorded by tape or even written down in notes. Yes, this whole story smacks of the utmost idiocy and fantastic far-fetched lying, but it is amazingly enough what some people believe. Even now, five years later, the provably false fairy tale of the "nineteen hijackers" is heard repeated again and again, and is accepted without question by so many Americans. Which is itself a testament to the innate psychological cowardice of the American sheeple, i mean people, and their abject willingness to believe something, ANYTHING, no matter how ridiculous in order to avoid facing a scary uncomfortable truth. Use your heads for something besides a hatrack. Time to wake up America.
Posted by: Enlightenment | December 7, 2006 4:46 PM | Report abuse
Don't kid yourself, its not going to matter soon what party controls what, that age is over. In this dangerous time, courage, wisdom, and action is what counts. Have you noticed there is barely a word out of the Republican party? They know what is coming and in some ways, Bush and company are more then relieved that the responsibilty is now shared.
Posted by: nf | December 4, 2006 8:06 AM | Report abuse
Statewide Republicans may have outpolled their Democratic opponents 53-47 in this district; however, that is not a very large margin, particularly for a very dark red state like Texas. Furthermore, other than the Governor's race, Demacrats really did not make serious efforts in statewide races in Texas, while the DCCC is making a serious effort in this runoff. All things considered, the relatively close margin in statewide races in this district may give the Democrats some hope for an upset.
Posted by: Howard | December 1, 2006 11:50 AM | Report abuse
'Will writes: "Webb certainly has conveyed what he is: a boor. Never mind the patent disrespect for the presidency. Webb's more gross offense was calculated rudeness toward another human being - one who, disregarding many hard things Webb had said about him during the campaign, asked a civil and caring question, as one parent to another."
This is truly Washington, in case you wonder what Washington truly is. Washington is a place where politics is just something you do all day. You lie, you send kids to war, you give them inadequate equipment, they're wounded and permanently maimed, they die, whatever. Then night falls, and you actually think you get to pretend that none of it matters. "How's your boy?" That, according to George Will, is a civil and caring question, one parent to another? It seems to me that it's exactly the sort of guy talk that passes for conversation in Bushworld, just one-up from the frat-boy banter that is usually so seductive to Bush's guests. George Bush once said to someone I know, "How old is that seersucker suit anyway?" and my friend (who should know better) went for it lock stock and barrel.
So finally someone said to George Bush, Don't think that what you stand for is beside the point. Don't think that because you're President you're entitled to my good opinion. Don't think that asking about my boy means that I believe for even one second that you care. If you did, you'd be doing something about bringing the troops home.
George Will thinks this is bad manners.
I don't.
I think it's too bad it doesn't happen more often.'
Posted by: Anonymous | December 1, 2006 8:49 AM | Report abuse
A long shot perhaps but Dems have nothing to lose in trying and are bolder now trying to compete everywhere thanks to Howard Dean.
Posted by: Intrepid Liberal Journal | December 1, 2006 6:28 AM | Report abuse
I'll accept whatever RMill observes and predicts.
Posted by: Nor'Easter | November 30, 2006 10:48 PM | Report abuse
It was my understanding that Democrats ran a slew of candidates in this district in an effort to keep Bonilla below 50%. The 20% for Rodriguez should be less indicative of his chances than the 49% or so of votes that were cast for a Democrat or the 51% cast for someone besides Bonilla. The fact that Democrats now control the house could also change the dynamic of the race, though it's entirely likely that that will depress turnout from both parties. Should be an interesting race either way.
Posted by: peter | November 30, 2006 9:57 PM | Report abuse
"Even with the DCCC's investment, a win in this district looks like a long shot."
As did the Dem takeover of both the House and the Senate at the beginning of the summer.
Posted by: Judge C. Crater | November 30, 2006 6:33 PM | Report abuse
The comments to this entry are closed.


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Sarka Pancochova says she's 'all good' a day after scary snowboarding crash
A day after her scary crash on the snowboard course, the Czech Republic's Sarka Pancochova reassured fans that she's "all good." Pancochova, 23, took an ugly tumble Sunday during the women's slopestyle finals. She missed her landing and broke her helmet on impact.
There was likely a "gasp" from TV viewers who saw the crash during NBC's Sunday night TV coverage. Fear not, Pancochova woke up the next morning and posted her broken helmet on Instagram along with a message that told us she was OK — and she had a sense of humor about her fall.
I guess I hit my head yesterday. Haha. Haven't gone down like this in a long time. But I'm all good that's everyone for they kind words.
(We assume she means "thanks" there toward the end).
Pancochova could have been a lot more heartbroken, considering she was in the lead after her first run. She finished the event in fifth place. Team USA's Jamie Anderson eventually won the gold. Even before Pancochova's crash, the safety of the slopestyle course had been a big talking point at the Sochi Games.
Related Olympics coverage on Yahoo Sports:
- - - - - - -
Mike Oz is a writer for Yahoo Sports. Have a tip? Email him at firstname.lastname@example.com or follow him on Twitter! Follow @MikeOz


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What We Do
and Who Helps Us Do it!
HER STORY THEATER creates original plays based on Chicago lives that relfect national concerns. We are a theater for social change.
Our Mission: Through theater and the written word, shine bright lights in dark places on women and children in need of social justice and community support.
We believe that if our audiences see what's in their backyards they will identify with the issue, make it personnal and take action.
HST partners with various organizaitons. We fundraise and advocate for their cause through the theater.
We focus on homelessness, domestic sex trafficking, violence, antisemitism, racism.
We provide main stage production on various social issue; our local and national Side Show series for professionals, educators and youth in raising awareness on domestic sex trafficking of minors; Educational Outreach; and our Chicago Writers Exchange for of any genre or gender focused on sociall issues.
Scripts are available to other theaters and organizations outside the greater Chicago area for awareness raising.
We are a grassroots professional theater company with a number of volunteers and professional artists who give of their time and talent. We are a 501 (c) 3 not-for-profit corporation.
Oppenheimer Family Foundation
Illinois Arts Council
Chicago Teachers Union
Congresswoman Jan Schakowsky
Northern Tier Judge Joseph McGraw
Delta Sigma Theta Sorority Alumnae
Sunlight Project 4th Presbyterian Church
National Council of Jewish Women North Shore
Chicago Communities in Schools
After School Matters
Chicago Cultural Center DCASE
Deborah's Place
Congresswoman Jan Schakowsky
Federal Judge Virginia Kendall
Cook County States Attorney Kim Foxx
Former Cook County States Attorney Anita Alvarez
Brenda Meyers Powell Co- Founder Dreamcatcher
Stephanie Wilson Daniels Co-Founder Dreamcatcher
CTU President Karen Lewis
Anne's House Director Frank Massolini
Paul Olson Retired Vice Squad Detective
Al Krok Retired Undercover Detective
Laura Ng, E.D. Traffick Free
Ann Breen Greco Administrative Judge
Dr. Jody Raphael Reseacher, DePaul Univ.
Chicago Tribune Columnist Eric Zorn
The Reader Colunist Ben Joravsky
Victory Garden A.D. Chay Yew
Joel Daly Retired Newcaster
Dennis Zacek Founder Victory Gardens Theater
Sylivia Ewing Columnist
Cheryl Lynn Bruce Award Winning Actress
Gary Houston, Managing Editor, Chicago Quarterly Review
James Sherman Noted Playwright
Robin Robinson CPD Community Outreach, Newscaster
Bill Curtis Newcaster, Celebrity
Donna LaPietra Executive Director Curtis Production
Vicky Curtiss Associate Pastor 4th Presbyterian Church
Alex Kotlowitz Noted Author
Phillip Van Lear Actor
Madrid St. Angelo Actor
Dee Alexander Jazz Singer
Lynn Jordan Jazz Singer
Jennifer Decker A.D. Mildred's Umbrella
HER STORY THEATER is a not-for-profit corporation 501(c) 3.


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A place to find out more and share what you know about this awesome rare poultry breed! **NOTE: Those who wish to register as a new member on the forum are asked to email firstname.lastname@example.com and an Administrator will gladly help you join the forum!
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Just out of quarantine, here is my new rooster and three pullets from gubi. So far he is liking the ladies but is quite the gentleman, considering he came from a bachelor pad and was isolated for 4 weeks. The 3 pullets have just started to lay and have introduced them to the older girls who's pen they will be sharing. The older girls were being a bit mean so I put my Bielefelder rooster in there to keep the peace and he is doing an amazing job
Last edited by Flat Rock Farm (2014-09-30 19:33:17)
They must like your place I'm still waiting for eggs here. The rooster came to my place as a chick from Micah and Kiah.
Ah I thought he was from your birds. He seems to have a good temperament so far. Yes all three of the pullets are laying there was three pullet eggs in the nest box yesterday.
Last edited by Flat Rock Farm (2014-10-01 00:26:27)
He's an Elevator son out of the pullets Kathy got from me. Double checked the pullet pen tonight nope no hidden nests.
Very nice new additions to your marraduna flack Flat Rock Farm. Bet you can hardly wait to let them make babies
Gubi I wonder if FRF has supplemental lights to extend the day and that is why she is getting eggs and you aren't?
Yes PG can't wait until Spring !!! Even though he has a bit too much grey in his chest I think overall he is pretty good.
No I do not supplement light to anyone this time of year. I will once we get into the depths of winter.
Even though there are a few colour wobbles, boy do you have yourself some gorgeous "barns"!!!! Can't wait to see what they produce in the spring!
Thanks Lisa, I hope so. This year was a disappointment so hoping for better next spring


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My R.E.M. top 10
It was a fantastic show, but I'm saving my verbiage for a review in the Chronicle. Since the band crisscrossed their entire career in the setlist, I'm inspired to name my ten favorite Stipe/Mills/Buck/Berry compositions.
10."At My Most Beautiful" (1998)
Peter Buck's Beach Boys influence at its most naked.
9."It's The End of the World as We Know It (And I Feel Fine)" (1987)
A total classic.
8."Let Me In" (1994)
The stirring and depressing tribute to Kurt Cobain, nearly played on one fuzzed-out guitar.
7."Flowers of Guatemala" (1986)
Their best early ballad.
6."Man on the Moon" (1992)
My favorite of their "biggest band in the world" era hits. Now connected with the Andy Kaufman bio-pic, it's many times more poignant.
5."Stand" (1989)
Endlessly rewarding dunce-pop.
4."Country Feedback" (1991)
Ominous – more ominous than it should be, at this point in the band's life.
3."The Sidewinder Sleeps Tonite" (1992)
Basically improves on the formula of "Losing My Religion" (a great song, by the way) and adds the saddest keyboards this side of Bauhaus.
2."Harborcoat" (1984)
My favorite of their early jangle-rock tunes.
1."Imitation of Life" (2001)
It's an unpopular choice, but that's because everyone's wrong and I'm right. This is a perfect pop song, larded with hooks (the riff, the strings, "That's cinnamon, that's Hollywood," "Cry-ei-ei-ei-ei-ei") and deceptively simple lyrics. And I've always dug the production on Reveal.


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text:
The John's Lane Distillery, founded in the year 1791 by James Power, an inn keeper from Dublin, was quite possibly the most beautiful, efficient and perfect distillery visited by Alfred Barnard in 1886 –maybe explaining why he devoted a full 6 pages in his book to it, more than for any other distillery in Ireland. This great power house of Irish distiling started life on a very small scale - it was a tiny distillery producing 6,000 gallons, situated behind James Powers' public house, from where mail coaches heading west out of Dublin would begin their journey. It did not stay small for long, and expanded rapidly after the 1823 Excise Act, which changed the limitations and taxations previously imposed on distillers. James Power's son, John, acquired a 500-gallon still and by 1833 they were producing 300,000 gallons a year. They did extensive rebuilding and expanded hugely in 1871 and when Alfred Barnard made his famous visit, output was at an impressive 900,000 gallons per year, slightly less than what the Jameson Distillery was producing.
The building was an ultra modern efficient complex, covering six-and-a-quarter acres of ground and offices, all the way from Thomas Street to the Quays by the river Liffey. There were open staircases throughout the five grain floors. These floors were beautifully clean and well ventilated and contained most of the time over 3,000 tonnes of grain. The kilns were 57 feet by 30 feet, with open groined roofs, lined with wood and stained oak, making them look like small English parish churches. The Mill room produced 1,500 barrels every twenty-four hours. The Still House was a noble looking building, containing five pot stills in 1886 and six by the turn of the century, the largest being the two Wash Stills, each holding 25,000 gallons. Powers produced triple distilled pot still whiskey, made from a mixture of malted and unmalted barley, with a small proportion of wheat or oats added, as was the custom in Ireland at the time. This new spirit would be put into casks and into any of the 17 warehouses which could hold up to 12,000 casks at any one time. The Distillery also had splendid outlying bonded warehouses under Westland Row Railway Station and under the South City Markets, which brought the total warehousing capacity to 40,000 casks. Barnard was particularly impressed by the warehouses underneath the new City Markets, with brick arches, supported on rolled iron beams and perfectly ventilated by large windows, the temperature being carefully monitored in both summer and winter.
The Powers were noted breeders of shire horses and in the premises in Thomas Street there were large stables and even a "horse hospital" for any horses who fell ill. There were also engineering shops, sawmills, carpenters, coppersmiths and fitters and the distillery employed 275 men. Barnard noted interestingly that the water used in the Distillery was principally from the river Vartry and that some of the old fashioned customers sent two empty casks with their order – one to be filled with Powers' whiskey, the other to be filled with water from the Vartry, in order to reduce their whiskey with same water as had been used in the making of the spirit.
The Distillery had its own fire department, manned day and night by a team of 8 men and the alarms were connected through the exchange to the city Fire Brigade. In case of fire, the water supply was destined to come from the Vartry, the Grand Canal and the Royal Canal and the distillery had its own stationary horizontal double-acting fire engine, capable of throwing 800 gallons of water per minute through eight lines of hose to a height of 150 feet.
In 1866, John Power & Son began bottling their own whiskey, which was unheard of before in Ireland, as it was usually sold in the cask. The gold label was entrusted on the bottle and it was from this that the whiskey got its name "Powers Gold Label". As the distillery and the brand grew, so did the stature of the family - John Power first was made High Sheriff of Dublin, then knighted in 1841 - after which the firm traded as Sir John Powers & Son - and it was he who laid the foundation stone to the O'Connell Monument in Dublin in 1854. The last member of the family to serve on the Board was Sir Thomas Talbot Power who died in 1936. The Powers distillery was a founding member of the Irish Distillers Group and ownership of the company remained in the family until 1966. John's Lane Distillery installed a column still in 1961, which they used primarily for the production of gin and vodka, but which was also used to experiment with producing grain whiskey for blending. They were instrumental in persuading the Irish Distillers Group to move from focusing on pot still whiskeys to blended whiskeys. The distillery finally closed its doors in 1974 when the Irish Distillers Group decided to move all its production, including that of Powers Whiskey, to the Midleton Distillery, where Powers whiskey is still distilled today. Interestingly, the stillhouse in the new distillery in Midleton with its interconnecting pot stills and column stills was modelled mainly on that of John's Lane.
So what has become of the distillery itself? Most of it, unfortunately has been demolished, some of it even before the closure and the move to Midleton. In 1980 Ireland's National College of Art and Design bought most of the site and the Counting House, a magnificent building on Thomas Street which was used as offices, Distiller's residence, still stands today. The Great Still House with its five pot stills that gleamed "like burnished gold" has unfortunately vanished, but three pot stills were spared and can still be seen today, outdoors, green with time and neglect. Part of the original Kiln building is still distinguishable from its circular shape and houses the College's library upstairs. Two of the original five Engine Houses have survived, the most notable being Engine House No.5 with its beam engine of 250 horse power manufactured by Turnbull, Grant and Jack of Glasgow in 1886. The double faced clock, admired by Barnard, set in the wall of the Engine House can still be seen today. Only the smaller of the original two chimney stacks has survived (95ft), the taller stack which stood at 120ft having been demolished for safety and insurance reasons, shortly after the College acquired the site.
Fortunately, the vestiges of the John's Lane Powers Distillery today are now protected structures, so they are likely to remain as a testament to this once great distillery. The College of Art and Design is not open to visitors as such, however, they are most amiable, and will accommodate anyone who wants to come in to see what is left of the distillery. If you are a big Powers whiskey fan, you may want to take this short pilgrimage to the spiritual home of your favourite whiskey, especially if you are visiting The Old Jameson Distillery, as the two are only about a 30 minute walk from each other. Call into reception at the college from the Thomas Street entrance, and explain that you would like to see the pot stills and old distillery. The Engine Room is not open for viewing, but you can wander at your ease in the grounds of the College where you can admire the stills, chimney stack and remaining architecture.
John's Lane Distillery – Thomas Street, Dublin 8
Tel. +353 01 6364291 (National College of Art and Design reception)
If you have any information, photos or know of any old bottles from the Powers Distillery in John's Lane, we'd love to hear from you, so please don't hesitate to contact us.
Further reading:
The Whisky Distilleries of the United Kingdom by Alfred Barnard


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Directions and Parking:
Free underground parking is available in the TEN20 building for all Bar Code customers.
Enter the TEN20 parking garage from the North-side of the building using NE 11th Street; please use
any of the numbered parking stalls. To access Grand Cru Wine Shop and Bar Code by
elevator, please use the "Retail Access" Elevator located on P1 near the main garage entrance. To gain
street level access please utilize the stairs located on each parking level.
Bar Code
1020 108th Ave NE, Suite 100
Bellevue, WA 98004
(425) 455-4278
From I-405 Northbound
1. Take exit 13A & 13B for NE 8th St.
2. Follow signs for NE 8th St W and merge onto NE 8th St.
3. Turn right at 108th Ave NE.
4. Bar Code will be on your right in the middle of the block.
From I-405 Southbound
1. Take exit 13B for NE 8th St.
2. Keep right at the fork, follow signs for NE 8th St W and merge onto NE 8th St.


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For those who like to stay active while immersing in cultural abyss, there are walking tours Italy to satisfy you needs.
Jan 11, 19 01:05 AM
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When it comes to facts about Italy - the list goes on and on. Italy gave birth such brilliant minds as Galileo Galilei, Leonardo Da Vinci and Michelangelo just to name a few. Their culture which dates…
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Still Feeling
"We are less lonely when we connect. Art is connection." - Nikki Giovanni
Still Feeling is a celebration of the human spirit. This film features four artists who are elevating their experiences of child sexual trauma through artistic expression; demonstrating the beauty of human resilience. Still Feeling, invites victims to connect with their family and friends, and journey with us. At the end of this feature length documentary, our goal is for victims to feel validated, and for their loved ones to be able to say, "Now I understand."
Our crew is traveling to Israel, Los Angeles, Chicago, and Canada to spend time with the artists, and document their artistic processes as they create and perform original pieces that communicate their experiences. After the performances, we will host two roundtable dinner discussions, one with the artists, and the other with a group of professionals in this area of trauma. This Kickstarter campaign is asking for $25,000 to finance the first segment of our film, to spend one week in Israel with Yuval Goldenberg.
Yuval's Story
Yuval is an up-and-coming singer/songwriter born and raised in Israel. Growing up on a Kibbutz in the north, Yuval was a great student, wonderful daughter, and loyal friend. But a dark secret was lurking in the shadows of her childhood. Without knowing how to get help, and carrying all of the shame on her young shoulders, Yuval turned the pain on herself and suffered terribly into her adolescence.
At her breaking point, Yuval started to write. She found the strength to transform her pain into powerful lyrics. At a time when Yuval's life was consumed by the pain, and her daily interactions were overpowered by the trauma, Yuval says, "My only lifeline was my music."
Today, Yuval chooses to come face-to-face with her pain rather than live in the shadow of the trauma. For Yuval, the essence of her story is about elevating her experiences. Every day is a struggle, and Yuval wants people to see what that struggle looks and feels like; and wants people to know that if hardship is met with determination, it can be the fire that ignites rather than burns.
Yuval has remained closely connected with the friends she has made along the way, and she is heavily involved with women's groups that support abuse victims. On March 8th, International Women's Day, our crew will film Yuval in a live performance at the Habima theatre with a group of women who have been working for the past year on a show that was written, produced, and features female victims and survivors. While in Israel, we will spend time with Yuval's family and friends as she communicates what she has learned on her journey, in the ancient land of Israel.
Check out Yuval's new release of "There is Life"
There is life
Lyrical translation:
Hey Listen to me
There is an eternity
Hit play to preview one of Yuval's songs.
Video Credits:
Lyrics and composition by Yuval Goldenberg
Lights, mix, sound by Shai Even and Roi Lidsky
Photography and video edit by Yony Yakoby
Director's Note
As a survivor of child sexual abuse who understands the need to be received in order to heal, I wanted to find a more effective way to connect family and friends to the experiences of other victims and survivors. I realized that art is a transcendent experience, engaging all types of people. And through the work of four courageous artists, we will bridge the gap between victims of child sexual abuse and their communities.
Where does your donation go?
To Israel! We will start our journey in the majestic, ancient land of Israel. Our team will work with Yuval to capture the essence of her story. Her performance will combine:
- Vlog footage
- Formal interviews
- Scene creation process
- The performance
Check out our budget below to keep up with every dollar that is donated:
By experiencing the artistic process from beginning to end, the audience becomes intimately aware of the physical, psychological and emotional effects of this trauma.
Massachusetts Citizens for Children, our proud collaborator
MassKids was founded in 1959 to "improve the lives of the state's most vulnerable children through advocacy by concerned citizens." And since its inception, MassKids has been one of the leading child sexual abuse organizations in all of North America, actively working to end this epidemic.
Still Feeling, the film, has collaborated with MassKids because of their innovative, hands-on, progressive approach to ending abuse. As our fiscal sponsor, MassKids allows our project to accept donations that are 100% tax deductible.
To learn more about child sexual abuse and how to prevent it, visit www.enoughabuse.org
Risks and challenges
The purpose of this campaign is to crowdfund the production costs for Yuval's segment of our film, and to make it in time for her performance on March 8th. That gives us exactly one month to fundraise and start production simultaneously. This is an enormous feat - and that's precisely the reason we are campaigning through Kickstarter.
Normal film grant cycles take months before any money is attained. But Yuval's story is happening now. On March 8th, Yuval stands on the largest theatre in Israel and performs with other women who were abused in order to share her experience with a large audience. This is our story within a story, and it's a once-in-lifetime shot!
We believe that our audience wants to make this happen, and that the crowdfunding community will come through in this crunch time to invest in Yuval and to support Still Feeling, the film!
We are a resilient team of artists and filmmakers who will do whatever is needed to raise the funds necessary to create this documentary, and we appreciate all of your support.Learn about accountability on Kickstarter
Questions about this project? Check out the FAQ
Funding period
- (30 days)


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Implementation of New System
It actually begins right now with you and your AMS sales representative. Identifying your needs, concerns and goals is the starting point on the road to successful implementation. Once we have determined if we can meet your requirements, we go to work on your plan. This plan, and all other information gathered during the sales and selection process is shared with our trainers and technical support staff who take it from there. The end result – another successful implementation!
Updates | Technical Support Updates
Our clients remain on active support with us year after year because they have come to rely on our timely software updates and dedicated people who will answer their questions, help with problems, or discuss their needs. This is an excellent indicator of just how good our service is, and your assurance that your medical software investment doesn't become obsolete. Updates are available 24/7 on our Tech Support Website. We send an e-mail newsletter to our clients with information on updates and other pertinent information.
Friendly and Knowledgeable Technical Support: 100% USA Based!
American Medical Software provides customer service/technical support to our clients nationwide who speak directly to our skilled technical staff at our headquarters. Updates and annual enhancements are part of standard support services. Priority Support/Updates and Telephone / web training is included for the first 3 months.


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Bank Card Delinquencies Drop To Lowest Levels Since 2002
Despite high unemployment rates and record foreclosure and mortgage defaults, Americans are working hard to pay down debt, as evidenced by a recent report.
According to the Mortgage Bankers Association, the Consumer Credit Delinquency Bulletin - which tracks eight closed-end installment loan categories - declined from 3.19 percent in the previous quarter to 2.98 percent currently, marking a drop of 21 basis points.
Bank card delinquencies also declined one-half basis point to 3.88 percent. The current rate is the first time since 2002 that the delinquency figures have fallen below 4 percent. Upon noting that the home equity delinquency rate fell from 4.32 percent last quarter to its current 4.12 percent - the lowest level in two years - the ABA expressed that the housing market may be slowly stabilizing.
"It's clear that consumer balance sheets are improving. People are borrowing less, saving more and building wealth. These are all positive signs," ABA chief economist James Chessen said.
Although Americans appear to be improving their finances, many facing bankruptcy or foreclosure are still seeking some form of debt relief. Credit counseling has been encouraged by many experts as a way to build a budget and explore repayment options.
New government regulations in place for consumers in need of debt relief for credit cards and other unsecured debts.


text:
If you are looking for a spa manicure salon in Coronado, CA, come to Coronado Fashion Nails. We are the best salon in the area, and can provide you with a variety of services. We are a full service nail salon, giving you the full experience you deserve for your nails.
On top of nail care, we also offer a manicure and pedicure to get all your nails looking great. If gel nails are a must for your look, we are more than happy to serve them to you along with a quality foot massage. This will allow you to get the highest quality look for your nails.
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Contact Coronado Fashion Nails today for more information on all of our beauty and nail services!


text:
SYDNEY: The Japanese yen, gold and sovereign bonds all rose on Monday as North Korea's latest nuclear test, and reports Pyongyang was making preparations for another missile launch, provoked the usual knee-jerk shift to safer harbours.
The dollar was marked down to 109.57 yen, having been as low as 109.22 and off a whole yen from late on Friday.
Japan is the world's largest creditor nation and traders tend to assume Japanese investors would repatriate funds at times of crisis, thus pushing up the yen. Many wonder, however, if Japanese assets would really remain in favour if an actual war broke out in Asia.
Japan's Nikkei did not take the news well, losing 0.9 percent. MSCI's broadest index of Asia-Pacific shares outside Japan slipped 0.75 percent with South Korea's main index down 1 percent.
"Like a bad horror movie, the North Korea saga intersperses moments of calm, with occasional action to jolt you out of your chair," said ING's head of Asian research Rob Carnell.
"But we have been here now many, many times," he added. "Unless this is the precursor to U.S. military action, which we doubt, then in a little over a day or two, tensions will calm again, making this a good buying opportunity for investors with a strong enough nerve."
European bourses looked set to open lower with Eurostoxx 50 and FTSE futures off 0.4 percent and the DAX contract down 0.6 percent.
North Korea on Sunday conducted its sixth and most powerful nuclear test, which it said was of an advanced hydrogen bomb for a long-range missile, prompting the threat of a "massive" military response from the United States if it or its allies were threatened.
Speaking outside the White House after meeting with President Donald Trump and his national security team, U.S. Defense Secretary Jim Mattis said Trump asked to be briefed on all available military options.
On Monday, news agency Yonhap reported North Korea was seen to be making preparations for another ballistic missile launch, possibly of ICBM-class.
Futures on 10-year U.S. Treasuries climbed 7 ticks, while yields on Japanese 10-year government debt rallied to their lowest since last November.
E-Mini futures for the S&P 500 dipped 0.4 percent, though U.S. markets will be closed on Monday for the Labor Day holiday.
The dollar slipped to 0.9591 Swiss francs from 0.9646, and was off 0.25 percent against a basket of currencies at 92.583. Gold hit a 10-month high and was last up 0.9 percent at $1,337.14.
The euro was 0.3 percent firmer at $1.1898, though investors were wary ahead of a European Central Bank meeting on Thursday.
There have been reports some at the ECB are unhappy with the euro's strength and are in no rush to signal the start of a tapering in its massive balance sheet.
Wall Street had ended last week on a mildly positive note after a tepid U.S. jobs report kept expectations muted for another interest rate hike this year.
The Dow ended Friday with a gain of 0.18 percent, while the S&P 500 added 0.20 percent and the Nasdaq 0.1 percent. [.N]
U.S. job growth slowed more than expected in August after two straight months of hefty increases. Nonfarm payrolls increased by 156,000 last month, while economists had forecast an increase of 180,000.
On a brighter note, the Institute for Supply Management reported its factory activity index soared to 58.8 in August, the highest reading since April 2011.
That was just the latest sign that global factory growth was gaining traction and added to bullishness on industrial metals. Copper climbed 1 percent on Monday to hit its highest in three years.
In the oil market, prices were subdued as shutdowns of U.S. production following Hurricane Harvey were balanced by an expected downturn in crude demand as the storm knocked out refineries along the Gulf of Mexico.
Brent crude shed 54 cents to $52.21, while U.S. crude eased 4 cents to $47.25 a barrel.
Your guide to the latest election news, analysis, commentary, live updates and schedule for Lok Sabha Elections 2019 on firstpost.com/elections. Follow us on Twitter and Instagram or like our Facebook page for updates from all 543 constituencies for the upcoming general elections.
Updated Date: Sep 04, 2017 14:01:11 IST


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So it was great to see the two Nick's trying out a starter battle.
Nick A had 3 x Martian Assault Walker and Nick S had a load of US Tanks with stands of HMGs, Infantry units, Roughriders on motorbikes and a Command Unit. Each Infantry unit had a forlorn hope section that could assault the Martians.
The US troops also had a rule where they can spend command tokens to bring back destoyed units as reinforcements. However, all this didnt make much difference as the Alien Death Machines heat rayed everything in front of them and march on with their invasion relentlessly.
|Martian Advance
|Civilians run for their lives
|Infantry cautiously move into position
|Armoured attack
|Armour flank the Martians
|Heat Ray disintergrates poor soldiers
|Enter the Roughriders
|Battle is fierce
|Command call for reinforcements
|The Martians victorious continue the invasion


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- Software
- Open Access
Integrating computationally assembled mouse transcript sequences with the Mouse Genome Informatics (MGI) database
© Zhu et al; licensee BioMed Central Ltd. 2003
- Received: 9 October 2002
- Accepted: 19 December 2002
- Published: 3 February 2003
Databases of experimentally generated and computationally derived transcript sequences are valuable resources for genome analysis and annotation. The utility of such databases is enhanced when the sequences they contain are integrated with such biological information as genomic location, gene function, gene expression and phenotypic variation. We present the analysis and results of a semi-automated process of connecting transcript assemblies with highly curated biological information for mouse genes that is available through the Mouse Genome Informatics (MGI) database.
- Additional Data File
- Mouse Genome Informatics
- Component Sequence
- Tentative Consensus Sequence
- Electronic Transcript
The volume and diversity of expressed sequence tag (EST) data in the public databases makes them an important resource for gene identification, genome annotation and comparative genomics. The value of EST data is enhanced when the sequences are clustered (on the basis of sequence overlap) to reduce redundancy. In some cases these sequence clusters can be used to generate a consensus sequence that represents a virtual transcript. Examples of electronic transcript data resources include UniGene [1], TIGR Gene Indices [2,3], DoTS [4] and STACK [5]. Each of these resources differs in the methods used to reduce the redundancy in EST sequence data and in how the data are represented. For example, UniGene uses pairwise sequence comparisons to group and partition EST and other transcript sequences from GenBank into gene-orientated clusters with no consensus sequence. The other three resources (TIGR Gene Indices, DoTS, and STACK) cluster sequences from ESTs and known transcripts and then assemble the members of each cluster to produce a consensus representation of the transcripts. The algorithms and/or parameters used to guide the clustering and assembly process for the virtual transcript resources are similar, but not identical. These resources also differ with respect to the number of species for which EST assemblies are available. For example, the STACK database includes only human sequence data, DoTS has both human and mouse assemblies, and TIGR Gene Indices maintains separate electronic transcript databases for over 50 species. In contrast to computational approaches to transcript analysis and representation, the Mammalian Gene Collection (MGC) [6] and the RIKEN Mouse Encyclopedia projects [7] are systematically generating full-length cDNA clones with the aim of having at least one full-length clone reagent and sequence for every human (MGC) and mouse (MGC, RIKEN) gene.
Selected database content statistics for the MGI information resource
Genetic markers
Genetic markers mapped
Genes mapped
Curated mouse/human orthologs
Genes with molecular probes and segments data
Number of genetic markers with molecular polymorphisms
Number of genes with molecular polymorphisms
MGI markers with GenBank sequence associations
Genes with SwissProt-TrEMBL protein sequences
The utility of both experimentally and computationally derived transcript resources are greatly enhanced when the transcripts are associated with well curated biological knowledge about the genes with which the transcripts are associated [11]. However, manual curation of computationally derived transcript data is not feasible because the underlying data for these resources are constantly changing. Therefore, we have developed a semi-automated curation process to create and update associations between constantly changing electronic transcript databases and the genes represented in the MGI database. Associations are based on GenBank sequence accession identifiers shared between MGI genes and transcript clusters/assemblies. Although associations between the genes in MGI and the electronic transcripts could also be made on the basis of sequence similarity, the use of shared accession ids is faster and avoids inconsistencies in sequence-to-gene associations that arise from highly similar sequence among members of multigene families.
Transitive associations between MGI genes and assembled transcripts
We first generated a set of GenBank sequence accession identifiers that have trusted associations (that is they have been manually curated) with mouse genes represented in MGI. A daily report of the associations of MGI markers and GenBank sequences, MRK_Sequence.rpt, is available from the MGI public FTP site [17]. We removed sequences associated with more than one gene object in MGI (for example, large cloned inserts containing multiple genes) to avoid confounding multiple genes to sequence associations. After this filtering step, the relationships of MGI genes to GenBank sequences were maintained in a dictionary data structure, MGI-GB, with MGI accession numbers as keys and GenBank accession identifiers as values.
A second dictionary, GB-MGI (GB as keys and MGI as values), was generated by reversing the keys and values of MGI-GB. A report with all DT identifiers and their constituent GenBank sequences accession identifiers, musDoTS_rel5_accessionsPerAssembly.dat.gz file (Release 5.0, 19 August 2002), was downloaded from CBIL's website [18].
A report containing TIGR Mouse Gene Index TC identifiers and their constituent GenBank sequence identifiers was generated from TIGR Mouse Gene Index Release 9.0 (October 1, 2002) (Geo Pertea, personal communication). This report was used to create two dictionaries, TC-GB (TC as keys and GB as values) and GB-TC (GB as keys and TC as values) to map TCs to GenBank sequence accession ids. There were many more GenBank sequences (mostly ESTs) in the TIGR Mouse Gene Index than in the MGI database because the TIGR Mouse Gene Index was built on all available GenBank sequences, and MGI curated only a subset of them (mostly mRNA and RefSeq sequences). Only GenBank sequence accession identifiers that appear in the MGI database were retained in TC-GB and GB-TC because those sequences will bridge the transitive associations between MGI genes and TCs. Sequences associated with more than one TC were removed.
Statistics of associations between MGI genes and transcript assemblies
TIGR TCs
DoTS DTs
Sequences used to build TCs and DTs
Sequences included in the assemblies (excluding singletons)
Assemblies (excluding singletons)
GenBank sequences shared by MGI markers and assemblies
MGI genes linked to assemblies through GenBank sequences
Assemblies linked to MGI genes through GenBank sequences
Two other dictionaries, TC-GB and GB-MGI, were used to link TCs to MGI genes in the same way. A dictionary, TC-MGI-via-GB (TC as keys and MGI as values), was used to maintain links from TCs to MGI genes and the supporting GenBank sequences. Figure 2b shows examples of links from TCs to MGI genes with the supporting GenBank sequences. 19.8% (20,942 out of 105,520) of TCs (excluding singletons) were linked to one or more MGI genes.
The same approaches were also used to associate MGI genetic markers to DoTS DTs. A report with all DT identifiers and their constituent GenBank sequence accession identifiers was downloaded from CBIL's website (Release 5.0, 19 August, 2002). The musDoTS_1-7-02_containedIds.dat.gz file can be downloaded from this site [18]. The report lists both DoTS assemblies (excluding singletons) and singletons. We included only assemblies in our analysis. Statistics of associations of MGI markers and DTs are shown in Table 2. The analysis linked 83.5% (24,340 out of 29,144) of MGI markers with sequence information to 20.1% (25,799 out of 128,341) of DTs. It is not surprising that only about 20% of DTs or TCs can be associated with genes in MGI because the majority of the assemblies are composed solely of EST sequences and the MGI curation processes focus primarily on collecting and curating associations with genomic and mRNA sequence data. There are a total of 26,440 DTs (including singletons) with mRNA sequences and 20,908 of them have MGI associations. The remaining 5,532 DTs with mRNA sequences might represent alternative transcripts of MGI genes, known genes not yet represented by MGI, or novel genes. We will evaluate the component sequences of these DTs and incorporate them into MGI database over time through manual curation.
Classification of the relationships between MGI genes and transcript assemblies
Classification of associations between MGI genes and both DT and TC gene indices
One-to-one MGI gene to assembly
One-to-many MGI gene to assembly*
Many-to-one MGI gene to assembly†
Many-to-many MGI gene to assembly‡
The majority of the associations were one-to-one relationships: 16,996 MGI-to-DT and 13,451 MGI-to-TC. Among these, a large number of MGI genes (9,509 in MGI-to-DT and 5,742 in MGI-to-TC associations) have only single GenBank sequence. The remaining MGI genes in one-to-one category have two or more GenBank sequences associated with them. The one-to-one associations between MGI genes and TCs/DTs suggests that these genes have only one form of transcript or that the data needed to detect transcript variants is not yet available in public databases.
One-to-many associations between genes and transcripts are related to transcript diversity
The TIGR Mouse Gene Index and DoTS databases are transcript orientated. That is, the sequence clustering and assembly process seeks to generate distinct assemblies for every form of transcript. The MGI database is gene-centric and associates transcripts from the same locus to a single gene object in the database. Therefore, in many cases, there are multiple TCs/DTs associated with a single gene in the MGI database. The average numbers of DTs/TCs per MGI gene among the one-to-many associations were 2.29 and 2.24, respectively.
Multiple TCs or DTs could also represent products of transcription from alternative promoters and/or polyadenylation sites of a single gene. For example, Dtna (dystrobrevin alpha) in the MGI database (MGI:106039) was associated with five TCs (TC546133, TC569762, TC577975, TC590157, TC633947) and with five DTs (DT.50316348, DT.60101497, DT.87050693, DT.91340878 and DT.91393353). The Dtna gene has three promoters that are active in tissue-specific manner [22]. Figure 3b clearly shows multiple transcripts from three promoters of Dtna gene on mouse chromosome 18. Experimental results suggested that Ncam1 contains more than one poly(A) addition site and produces transcripts with different 3' untranslated regions [19]. Figure 3a demonstrates that multiple virtual transcripts with different 3' ends align the Ncam1 gene on mouse chromosome 9.
Another explanation for one-to-many MGI gene to DTs/TCs associations is multiple site-specific recombination or DNA rearrangement that occurs normally in certain cell types. For example, the Igh-VS107 (immunoglobulin heavy chain (S107 family)) locus in MGI (MGI: 96490) was associated with four TCs (TC632874, TC632875, TC632877 and TC643641) and with three DTs (DT.94166135, DT.94209475 and DT.94398318). All above TCs/DTs and sequences associated with Igh-VS107 were mapped to the same locus on chromosome 12 using the UCSC genome browser (data not shown). The sequence differences of Igh-VS107 transcripts are readily explained by normal DNA rearrangements (V(D)J recombination) [23]. Another example is that H2-Eb1 (histocompatibility 2, class II antigen E beta) in the MGI database (MGI:95901) was associated with four TCs (TC575977, TC608775, TC638140 and TC640785) and with two DTs (DT.493389 and DT.55100612). The H2-Eb1 gene contains a recombination hotspot, which has a predominant role in generating different recombinants through meiotic crossing-over within the I region of the mouse major histocompatibility complex (MHC) [24]. All above TCs/DTs except TC575977 and DT.55100612 were mapped to annotated H2-Eb1 gene on chromosome 17 using the UCSC genome browser (data not shown). TC575977 and DT.55100612 were associated to H2-Eb1 through one GenBank sequence AK012147, which was mapped to chromosome 5. Further analysis indicated that AK012147 was incorrectly associated with H2-Eb1.
Non-biological explanations may also explain some of the one-to-many associations among genes and transcripts in our analysis. For example, low-quality sequence data or problematic sequences that are not filtered out before clustering and assembly can cause errors in the sequence assemblies. Another possible explanation is that nucleotide and protein sequences are occasionally associated with the wrong gene in MGI. This will always be a challenge to the database community when both completeness (including as much data as possible in the database) and accuracy (associating every sequence to the right gene) are goals. Fortunately, non-biological reasons for one-to-many associations between transcripts and genes only account for a small percentage of the whole dataset based on our experience of ongoing internal quality control and manual check of portions of the data in this analysis.
The many-to-one associations between genes and transcripts are evidence for over-clustering or gene redundancy in MGI
In the analysis reported here, 14.8% (4,302 out of 29,144) of MGI genes with sequence information were involved in many-to-one gene to TC transcript associations and 12.4% (3,621 out 29,144) in many-to-one gene to DT transcript associations. The average numbers of MGI genes per DT/TC were 2.16 and 2.23, respectively. First, some of the many-to-one associations are due to sequence clusters that contain mistakenly grouped similar sequences from closely related genes (paralogs). For example, sequences from 14 members of the defensin-related cryptdin gene family were clustered into one TC (TC6H932) and to one DT (DT. 94272645). These genes share similar structure and sequence. Their mRNAs are distinguished by a 45-nucleotide 5' untranslated sequence (UTS) encoded completely by the first exon [25]. Second, genes adjacent to each other in the same chromosomal location were occasionally clustered together and assembled into one sequence because their transcripts overlap each other. For example, the 3' end of Stk11 (serine/threonine kinase 11; MGI:1341870) is in very close proximity to the 3' end of a functionally unrelated gene dos (downstream of Stk11; MGI: 1354170) and it seems that overlapping transcripts of the two genes are produced [26]. Both Stk11 and Dos were linked to one DT (DT.493186) because sequences associated with both genes were clustered and assembled together. Third, there are rare cases of polycistronic transcripts in mammalian genomes. For example, Snrpn (small nuclear ribonucleoprotein N; MGI: 98347) and Snurf (SNRPN upstream reading frame; MGI: 1891236) are expressed as bicistronic Snurf-Snrpn transcript [27] and both of them were associated with one single TC (TC619385) and one single DT (DT.535946) in our analysis. Finally, many-to-one associations can be caused by uncorrected gene redundancy (one gene represented by multiple entries) in the MGI database. The majority of the redundant records are the result of genes in MGI that are represented solely by EST sequences. As these redundancies are identified in MGI they are corrected.
Many-to-many associations between genes and transcripts could be the result of any combination of many-to-one and one-to-many associations
In the analysis reported here, we had 531 MGI-DT and 454 MGI-TC many-to-many associations. There were 4.1% (1,202 out of 29,144) of MGI genes with sequence information and 1,355 DTs involved in many-to-many MGI gene to DT transcript associations and 3.6% (1,044 out 29,144) of MGI genes with sequence information and 1,127 TCs in many-to-many MGI gene to TC transcript associations. The average numbers of MGI genes per DT/TC were 2.26 and 2.30, respectively, and the average numbers of DTs/TCs per MGI gene were 2.55 and 2.48, respectively. The majority of the many-to-many associations had only two MGI genes and two DTs/TCs. The group with the largest number of MGI genes in MGI-DT associations included eight paired-Ig-like receptor A genes (Pira1, Pira2, Pira3, Pira4, Pira5, Pira7, Pira10, Pira11) and two DTs (DT.87053023 and DT. 94272531). DNA blot analysis indicated the presence of multiple paired-Ig-like receptor A genes in the genome, and cDNA sequencing analysis suggested 0.2-4.7% frequency of overall nucleotide variations [28]. The group with the largest number of MGI genes in MGI-TC associations included six eosinophil-associated ribonuclease (Ear1, Ear2, Ear3, Ear8, Ear9 and Ear10) and RNA guanylyltransferase and 5'-phosphatase (Rngtt) and four TCs (TC561767, TC569331, TC557280 and TC557281). The mouse Ear family has at least 13 members, 11 functional genes and 2 pseudogenes [29]. The genes within this family share a common genomic structure that is conserved with primate Ear genes. The mouse Ear gene family forms four unique clades (Ear1/2/3/8/9/10 genes form subfamily A). The members of each clade share a high degree of sequence identity. Transcripts from Ear1/2/3/8/9/10 were over-clustered into one TC (TC561767). TC569331 was associated with Ear2 because of shared EST sequence AA510162 and associated with Rngtt because of shared GenBank sequence AK002922. Sequence analysis indicated that AA510162 encodes Rngtt instead of Ear2. Further analysis suggested that a typographical error in the publication [30] caused the reported EST sequence associated with Ear2 to be AA510162 instead of AA510161. This many-to-many association can be resolved into one many-to-one association (six Ear genes to TC561767) caused by over-clustering and one one-to-many association (one MGI gene Rngtt to three TCs) caused by transcript diversity. The group with the largest number of DTs in MGI-DT associations included 18 DTs and three immunoglobin heavy-chain genes (Igh-4, Igh-VJ558 and Igh-V). The group with the largest number of TCs in MGI-TC associations included 25 TCs and three immunoglobin heavy-chain genes (Igh-4, Igh-VJ558 and Igh-1). The complexity of the many-to-many associations demonstrates the challenges of creating links between genes and electronic transcripts and highlights the caveats that users of these resources must keep in mind.
Comparison of DoTS and TIGR Mouse Gene Index
For the one-to-one MGI-DT and MGI-TC associations, the number of shared sequences between DT and TC pairs linked to the same MGI gene varies
Comparison of the constituent sequences of TCs and DTs
DT and TC pairs analyzed*
DT and TC that have the same constituent sequences†
DT is a subset of TC†
TC is a subset of DT†
DT and TC assemblies that share one sequence
DT and TC assemblies that share 2-4 sequences
DT and TC assemblies that share 5-9 sequences
DT and TC assemblies that share 10-99 sequences
DT and TC assemblies that share 100 or more sequences
DT and TC assemblies that share zero sequence
For the one-to-many MGI-DT and MGI-TC associations, DoTS and TIGR Mouse Gene Index did not consistently cluster the GenBank sequences
There are 2,522 MGI genes associated with multiple DTs, and 1,975 MGI genes with multiple TCs. And 1,475 MGI genes had both MGI-to-TC and MGI-to-DT one-to-many associations. We considered all TCs or DTs associated with the same MGI genes as different forms of transcripts and grouped them together. We compared the identity and grouping of the component sequences between the TC group and its corresponding DT group. We included only the sequences curated in the MGI database in the comparison because they are mostly high-quality mRNA sequences and should be reliably clustered. There were only 245 pairs of the TC group and DT group associated with the same set of MGI curated GenBank sequences, which were also clustered in the same way. The remaining pairs differ either in their set of associated GenBank sequences or in the way of sequence clustering.
The differences between the two electronic transcript databases are likely to be due to the different criteria used by the two groups for clustering and assembly of EST and mRNA sequences. One possibility is different degrees of trimming poor-quality sequences from the ends of ESTs (C.J.S., personal communication). Less trimming in DoTS build might result in more assemblies than TIGR TCs. In testing, fewer larger assemblies were generated when trimming was not limited. Limited trimming was chosen in attempt to preserve better representation of differentially processed transcripts in DoTS build. The comparison of the two databases using curated data from MGI as a reference provides some measures to evaluate and improve computational methods.
Utility of the analysis
The association of MGI genes with electronic transcript assemblies supplies biological context to the computationally assembled transcripts and allows researchers to access these data from biological as well as sequence perspectives. The curation process described here permits us to rapidly build high-confidence associations between MGI genes and electronic transcript sequences. The results reveal the complications that can arise from the clustering process as well as errors in the MGI database. The assessment of the results will provide measures to evaluate and improve the EST-assembly protocols and to check the quality of gene representation in the MGI database.
Access to the links between the MGI database and the TIGR and CBIL electronic transcript databases
Only associations between MGI genes and TCs/DTs that are supported by non-conflicting evidence (one-to-one and one-to-many associations) are accessible from the web browsers for these resources. The links from MGI genes to TCs and DTs are available from the MGI gene detail pages. The links from TCs to MGI genes are available from TIGR's TC report page and through another TIGR database resource, RESOURCERER [31]. The links from DTs to MGI genes are available from Allgenes's DT report page [32]. Users can query for related DTs by MGI gene accession identifiers or symbols. The data files for MGI-DT/TC associations are available from MGI public FTP site [17]. These data will be updated after each build of TIGR's Mouse Gene Index and CBIL's DoTS database or after every major change in MGI databases.
Additional data files
The original datasets from TIGR (from TIGR Mouse Gene Index Release 9.0 (1 October 2002)), DoTS (from DoTS mouse assembly Release 5.0 (19 August 2002)) and MGI (11 October 2002) are available as additional data files. Links from MGI to the DOTS (one-to-one, one-to-many, many-to-one and many-to-many) and TIGR (one-to-one, one-to-many, many-to-one and many-to-many) electronic transcript associations from the analysis done on 11 October 2002 are also available as additional data files. The most recent data files for MGI-DT/TC associations can be obtained from MGI public FTP site [17].
This work was supported by the Department of Energy (FG02-99ER62850) and NIH/NHGRI (HG0030-P1). The comments of Martin Ringwald, Molly Bogue, and Dong (Donnie) Qi helped to improve the clarity of the manuscript. The authors thank Jim Kadin and David Miers (MGI Software Group) and Geo Pertea (TIGR) for their technical assistance.
Authors' Affiliations
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This article is published under license to BioMed Central Ltd. This is an Open Access article: verbatim copying and redistribution of this article are permitted in all media for any purpose, provided this notice is preserved along with the article's original URL.


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I've never been too keen on taking pictures. I'll be the first to admit I am not photogenic. And, while I have grown to be ok with that (my talents lie elsewhere ), I certainly enjoy seeing look posts on other blogs. Seeing what other people are wearing on a day to day basis is inspiring.
Since I have not yet mustered up the courage to do a regular look post, I have decided to do something slightly different. I wore this outfit to a Sunday lunch recently. I was immediately obsessed with this printed dress the moment I saw it. While it is perfect for summer; I can also wear it in the cooler autumn weather with stockings and a coat.
The shoes and necklace are some of my favourite statement pieces. I love the lace up and suede detail on the shoes and the necklace made me think of those Pichulik necklaces I have been dying to get. The snake skin detail on the side of the bag gives an otherwise very plain bag that wow factor. I cant wait to experiment with all these pieces and find new ways to wear them.
|How stunning is this bag!?
|A selfie of me in my favourite dress.
If you have posted a look on your blog recently please leave me the link in the comment section. I would love to read it. Other than that, have an amazing day!


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Altorfer Inc., a Caterpillar dealer serving 88 counties in Eastern Iowa, Northern Missouri and Central Illinois, opened a new facility recently in Springfield, Ill. The new facility will offer construction equipment, rental and on-highway truck repair services. The branch includes a Cat Rental Store.
Altorfer held an open house May 25 with almost 300 people in attendance, offering door prizes, equipment demos and facility tours.
"We are striving to provide our customers with a best-in-class customer experience," said Mark Hanson, vice president of Altorfer's construction division. "We are pleased to give our construction, rental services and power systems teams the opportunity to work in a modern, well-located, and professional facility. We are in position to serve our customers like never before."
Altorfer is based in Cedar Rapids, Iowa.


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Happy New Year from The Black Achievers Awards Team!
As we are still heading into the beginning of the year 2017 we are already starting the planning of this year's Black Achievers Awards. Last year was a successful comeback after Councillor Merlita Bryan had to miss out on a year due to her role as the Lord Mayor in 2014. We are planning to out-do last year's event so if you are a local business and would like to be involved in sponsoring the Black Achievers Awards this year, then please email us at email@example.com would like to continue to build on the relationship in the community by including the Nottingham Community as much as we can, so support us in spreading the word about this years event by following our social media platforms. Announcements of when the nominations will be open and the date of the event will be made soon. #baawardsnotts


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Cool career alert!
Bachelor of Aviation students at Griffith University could become future pilots with Qantas thanks to a new partnership.
The Qantas Future Pilot Program provides students with access to experienced pilots during their degree, with selected students invited to complete an intensive 12-week Airline Transition Course.
Graduates can then transition to employment with QantasLink and complete their training under the supervision of QantasLink's experienced training team and become qualified as First Officers flying the airline's Dash 8 200/300 or Q400 fleet.
The program is open to a potential pool of 300 students in the next few years.
QantasLink Chief Executive Officer John Gissing said the program would build the next generation of exceptional pilots from within Australia's top aviation schools and provided students with unparalleled benefits and job certainty not available with any other training program.
"Aviation students will have an enormous head start to their career as a pilot. They will not only benefit from a direct pathway to Australia's largest regional airline, but will also have access to experienced Qantas Group pilots throughout their studies," Mr Gissing said.
New pilots are usually only considered for employment with a commercial airline after spending time flying in the general aviation market, which is often gained by flying single-pilot charter aircraft usually in regional areas or by seeking employment outside of Australia.
"This fantastic initiative will equip high-performing and motivated students with the skills needed to transition into an airline and provide them with a platform from which to launch their career as a pilot within the Qantas Group.
"We are ensuring our students get the best possible start to their career and job opportunities secured early."
Head of Griffith Aviation Associate Professor Gui Lohmann believes that Griffith Aviation offers a suite of initiatives that put Griffith students ahead in the industry.
"In 2018, Griffith Aviation is launching new initiatives to make sure our cutting-edge degrees are at the forefront of aviation education," he said. "They include a new flight procedure lab, specific courses on Rotary Wings and UAVs, as well as the first ever Helicopter Pilot Training Graduate Diploma in Flight Management."
To be eligible for the Qantas program, students need to be enrolled in the Bachelor of Aviation program, hold a GPA of 4.0 or above for the duration of their studies, and have Australian work rights.
Why choose the Bachelor of Aviation at Griffith University?
Griffith University has one of Australia's largest and most highly recognised aviation teaching programs. Over the past 20 years teaching in this field, Griffith has built an international reputation for graduates who are industry ready. Griffith aviation staff have strong industry ties and are world leaders in aviation research.
The Bachelor of Aviation is a two-year, accelerated degree allowing students to progress more quickly into a flying career.
Students will be introduced to the sciences underpinning the theory and practice of aviation, and will also study courses in areas such as, navigation, planning, and the human factors in aviation. Through the Bachelor of Aviation, you will develop with the skills needed for lifelong learning in the evolving aviation environment.
The Bachelor of Aviation together with self-funded flight training will allow graduates to be ready to work in the aviation industry as a commercial pilot.
Program: Bachelor of Aviation
Location: Brisbane, Queensland
Semester intake: February each year
Duration: 2 years
Apply to the Griffith University aviation program!


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Today we're welcoming author Bri Clark to the blog on her tour with Bewitching Book Tours for her paranormal romance, "The Familial Witch". You can follow the rest of her tour here.
Now... here's Bri!
Sometimes you simply need to check out. Authors, artists, musicians, and even you need to recluse yourself from the world at times. There are multiple reasons for self-induced seclusion. A person may need a break from stress, emotional turmoil or certain people in their lives. Artists may hide themselves away in a studio creating their latest piece of soulful inspiration. The next club stomping hit may be mixing away now as we speak by a musician within the confines of their studio.
Then there is the author, the writer, the blogger and the poet, whatever you call them, they are all creators. Recently, I launched my own company called Belle Consulting where I do literary strategy. It immediately took off and I couldn't be more thrilled…or stressed.
Did you know that Public Relations is the 3rd most stressful job in the US—only coming in behind airline pilots and air traffic controllers? Reason being is you can work your butt off and still not have results. And you're paid to produce success.
So can you imagine trying to write a novel under all that constant worry?
With that said, my lovely, amazing, couldn't be more husband has sent me away for 3 days and 2 nights to finish The Eternal Witch. I was 3/4s of the way through it and I'm now going to finish.
As we speak, I'm at a lovely cabin on a lake in the mountains away from my business, family and life. And I am bound and determined to finish this novel and get started in the next if I'm lucky.
Lucien Lemione the clan leader of the feared and revered Eternals is faced with the ultimate betrayal. His second in command for two centuries has not only created the most grievous of offenses but also commissioned the creation of liquid silver. When poisoned by this toxin, an immortal suffers a fate much worse than death, frozen in an internal prison. After being wounded when found spying, he hides deep within the eerie woods that encircle the Triad Mountains. Desperate and in pain, he prays to an offended mother goddess for help. Her answer: a woman, but not just any woman. A witch.
After losing her entire coven at the hands of the Eternals, Aisleen is the last of her kind. She retreats from the world to Trinity Forest where she is giving the opportunity of a lifetime, or perhaps a test of principles. It's there she discovers the man she heals is the Eternal that wiped out her people. Although she is bound as a healer, she could be creative in her revenge. Aisleen knows who and what Lucien his…but does not speak of it. There can be no future with Lucien for she can only be with a mortal man. Even if she wanted to be with him, can she forgive the man that caused the genocide of her people?
Lucien must act quickly for the survival of his clan is at stake. However, Aisleen's ethereal beauty and emerald eyes keep pushing those thoughts far from his mind. Determined to find out what secret she hides, he prolongs his time with her. When his people need him most what will he choose…duty, desire, or will he make his own fate?
You can choose love but you can't choose destiny.
Amazon Buy Link
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Publisher Buy Link
Bri Clark is a real example of redemption and renewal. Growing penniless in the South, Bri learned street smarts while caring for her brother in a broken home. She watched her mother work several jobs to care for their small family. Once her brother could fend for himself, Bri moved on to a series of bad choices including leaving school and living on her own.
Rebelliousness was a strong understatement to describe those formative years. As a teenager, her wakeup call came from a fight with brass knuckles and a judge that gave her a choice of shaping up or spending time in jail. She took that opportunity and found a way to moved up from the streets. She ended up co-owning an extremely successful construction business. She lived the high life until the real estate crash when she lost everything.
She moved west and found herself living with her husband and 4 kids in a 900 square foot apartment. She now fills her time, writing, blogging, leading a group of frugal shoppers and sharing her southern culture. Her unique background gives her writing a raw sensibility. She understands what it takes to overcome life's obstacles. She often tells friends, "I can do poor. I'm good at poor. It's prosperity that I'm not used to."
Bri and her husband Chris live in Boise. Bri is known as the Belle of Boise for her true southern accent, bold demeanor and hospitable nature.
Bri boasts several positions in the publishing industry. An author, professional reviewer, blogger, and literary strategist she enjoys all aspects of her career from the creation of story to the branding and marketing needed to make her books successful.
Twitter, Facebook, G+, Goodreads, Blog


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11 Now faith is the substance of things hoped for, the evidence of things not seen.
2 For by it the elders obtained a good report.
3 Through faith we understand that the worlds were framed by the Word of God, so that things which are seen were not made of things which do appear.
4 By faith Abel offered unto God a more excellent sacrifice than Cain, by which he obtained witness that he was righteous, God testifying of his gifts; and by it he, being dead, yet speaketh.
5 By faith Enoch was translated, that he should not see death, "and was not found because God had translated him." For before his translation he had this testimony: that he pleased God.
6 But without faith it is impossible to please Him. For he that cometh to God must believe that He is, and that He is a rewarder of those who diligently seek Him.
7 By faith Noah, being warned by God of things not yet seen, moved with fear, prepared an ark for the saving of his house, by which he condemned the world and became heir of the righteousness which is by faith.
8 By faith Abraham, when he was called to go out into a place which he should later receive for an inheritance, obeyed; and he went out, not knowing whither he went.
9 By faith he sojourned in the land of promise as in a strange country, dwelling in tabernacles with Isaac and Jacob, the heirs with him of the same promise.
10 For he looked for a city which hath foundations, whose builder and maker is God.
11 Through faith also Sarah herself received strength to conceive seed, and was delivered of a child when she was past the age, because she judged Him faithful who had promised.
12 Therefore there sprang even from one, and him as good as dead, as many as the stars of the sky in multitude, and innumerable as the sand which is by the seashore.


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Inside Design all people can to find improvement from
Are you resentful of beautifully adorned residences? You do not have had to be jealous of their type. You can too flip your house right into a beautifully decorated house. You just have to have the right direction. Hold reading to learn the right way to make your residence into a magazine.
One thing that you just need to remember when designing a room of their condominium is to create a mood. Consider of a mood and stick to it when you're identifying which items for the room. For example, if you wish to obtain a peaceful mood, use colors that are delicate and warm.
Using things that may serve a couple of purpose can support you maximize a small spaces.
De-cluttering is the best solution to get all set for a residence renovation task.
Many humans have opinions in relation to inside design, however that you could most effective hearken to them a lot. You won't have the home you'll like living in the event you believe yourself and your interior design competencies.
When designing a child's room, use the baby's point of view when furnishing it. It might be easily forgotten that kids don't see it as they do. You will have to ensure all of these objects are placed in a spot that's effortless to your baby to entry. Appear at it as your child would and do away with view to avert doing anything hazardous.
They are additionally a part of the decor as the whole lot else. That you could feel of cool ways to design them in a bit planning. You are trying putting them within the right angles and patterns. Which you could swiftly alternate the room's mood and create a room through changing how your photographs are hung.
If in case you have flooring which are product of tile, stone or tile, the usage of elegant area rugs will make your room look cozier and warmer to your ft. Rotate rugs as the seasons change to include a fresh and coordinated aspect to your room.
Incorporating today's elements as you design will also be pleasant. They are able to modernize a room seem modern-day and fashionable. It is satisfactory to use cutting-edge accents to small items. A leopard print table runner is readily changed with a floral desk runner. A couch with zebra print isn't as with ease replaced.
Then you definitely do not have the have got to envy other superbly decorated residences. Taking copyright notice advantage of the assistance provided to you right here, which you could make your home the envy of the neighborhood. There is no purpose to preserve enabling yourself to be scared away with the aid of interior design and you will have to now be ready to sort out any assignment your house offers.