text:
KENSINGTON — Help start a new 4-H club for youth ages 5 to 8. Being sought are families interested in participating and adult volunteers to help run a club in the Kensington area.
KENSINGTON — Help start a new 4-H club for youth ages 5 to 8. Being sought are families interested in participating and adult volunteers to help run a club in the Kensington area.
The club meeting schedule would be arranged to best fit family schedules and would focus on hands-on fun activities that help youth connect with nature, learn about agriculture, and more. Older siblings and friends are welcome, but activities would be geared for the younger group.
If interested in participating or volunteering, contact Dawn Thurlow at firstname.lastname@example.com or the Rockingham County 4-H Youth Development office at 679-5616 or firstname.lastname@example.com.
4-H is the youth educational program of the UNH Cooperative Extension. The mission of 4-H is to help youth acquire knowledge, develop life skills and form attitudes to enable them to become self directing, productive and contributing members of society. 4-H emphasizes the importance of involving youth in the learning process.
For more information on 4-H and the UNH Cooperative Extension programs in Rockingham County, call 679-5616 or visit bit.ly/rockingham.
BRENTWOOD — Want to get rid of your used books? Brentwood Christian Academy is raising money through donations of new and used books, CDs, DVDs, records and audio books. The group recently placed a drop-off donation container to collect these items from community members who'd like to repurpose their used goods while also helping the academy raise money. The group will be paid on an ongoing basis for all items collected in their donation container.
The gray book donation container, distinguished by its purple and yellow "Got Books?" signs, is located outside of the school at 263 Route 125, Brentwood.
For more information contact Got Books at www.GotBooks.com or call 978-284-2500.
EAST KINGSTON — The East Kingston Public Library offers Boston Museum of Science passes, plus passes to both the Currier Museum of Art in Manchester, and the Peabody Essex Museum in Salem, Mass. The Currier passes will get you in for free, and the Peabody Essex passes are good for a reduced fee of $5 per person. Contact the library to reserve your passes today! It's time to get out of the house and enjoy some of New England's wonderful culture — how better to do that than visiting a fantastic museum?
EPPING — More than 150,000 troops are serving overseas and are away from their families. Donate your old cell phone and provide soldiers a much needed connection to their loved ones. There is a drop-off box at Epping Town Hall. If you have any questions, call Joyce at 679-5441 ext. 101 or visit www.cellphonesforsoldiers.com.
BRENTWOOD — The Brentwood Community Center is available for rentals to both residents and non-residents. If you're interested in booking a date, contact Margaret Dullea, Recreation Director at (603) 642-6400 ext. 20 or e-mail Dullea at email@example.com. The Recreation Department's office hours are Monday, Tuesday and Thursday from 9 a.m. to 2 p.m.
You may find about renting the community center at the Recreation homepage at www.brentwoodnh.gov. Necessary forms are there to be downloaded for your convenience.


text:
A Designer's Advice to Internet Entrepreneurs
1. Ask Yourself: "How Will this Idea Make Money?"
This point does not directly relate to design, but it does affect how your designers will carry out their jobs.
Any entrepreneurial endeavor should begin with this question: "How will this earn money?"
Whatever the answer is, that should be kept as your focus.
You may have the coolest, most original idea for a cloud-based e-commerce social-media dating site, but if you don't have a detailed, sensible business model to turn that epiphany into dollars and cents, then you will fail before even having begun.
I have seen plenty of really neat ideas fall flat — not because they lacked a one-word name like Crowdscratch or Zomgr, but because making money was an afterthought, not the first thought.
"We'll just run ads, I guess."
No, advertising is not a valid answer. In order for you to be profitable through advertisements, thousands upon thousands, if not millions, of unique visitors will need to come to your website each month.
Unless you are planning a content-based site, do not deceive yourself into thinking that a few bucks from banner ads will make your business profitable. It will be a thin piece of thread on which to hang your hope of success on.
2. Start Simple
"Rome was not built in a day," as the idiom goes. Too many startups never amount to anything because they do not know how to get off the ground.
Simply put, they want to do too much, too soon, and end up going nowhere at all.
For example, one entrepreneur I know of wanted to launch an e-commerce site that enables plumbers, mechanics, electricians and the like to find small parts that are essential to their trade.
Not a bad idea at all — that is, until halfway through the project, when he decided to turn it into a social media site, with a points system, leader boards, badges, the works, all in time for the launch.
Now, nothing is particularly wrong with a social shopping site for plumbers, but timing is critical.
Don't bite off more than you can chew.
Come up with a scope for the work, divide it into phases, and stick to the plan.
Your worst enemy is your own brilliance sometimes.
Usually, the simpler the site's functionality at the time of launch, the better. You will be able to keep costs down, market yourself with less difficulty and keep track of how the site is doing so that you can plan ahead.
You may realize that the plumbers of the world can do without their own social network.
3. Don't Worry About Things that Don't Matter
I've already talked about a website's name, but I want to reiterate the relative unimportance of it. I have seen many startup founders devote an insane amount of thought, energy and resources to whether their company is named, say, Catchfark or Catchfork. I have witnessed a company spend three months and great sums of money just on the little dog in its logo.
The same goes for other details that don't matter in the greater scheme of things; things that distract you from your mission and goals.
Whether the logo is a squirrel or a chipmunk, whether the stock photo on the home page is of a 28-year-old woman instead of a 24-year-old woman, or whether the blue in the header is two shades lighter than the target audience is expecting will not have as big of an impact as working on your core products and services. When you've got your core products and services down, then it's time to investigate minute ways and tweaks to supplement them, not the other way around.
It's not that these things don't matter, because they do. But they are not worth your time, energy, and sanity.
You have bigger fish to fry. You have a company to run.
Instead of stressing over tiddlywinks, hire experienced professionals and let them stress. Designers love to stress over minutia. That's what we are trained and paid to do. In fact, a true designer will care more about the way your company looks than even you do!
Plus, understand that your brand image will evolve over time. You don't know how people in the real world will respond to your product until they actually start using it. Everything up until that point will be almost purely subjective to you and a handful of people, all of whom have different opinions. Do not spend 12 hours of valuable time debating visual externals that might be irrelevant in 12 days.
4. Design is Not a Substitute for Marketing
Majoring in design is no excuse to minor in marketing. Design turns traffic into customers, but without marketing, you won't get any traffic. And without traffic, you won't get any customers. Period.
One client blamed our team of designers for his site's lack of users, alleging that the brand we had created was not compelling enough and the interface not usable enough.
Meanwhile, he had refused to pay for any marketing at all.
A sharp-looking website backed up by a solid business plan means nothing if no one knows it exists. People will not flock to your site simply because it is there.
"If you build it, they will come" might work for Kevin Costner, but for the rest of us, nothing but good marketing will bring people to anything.
I have seen a year's worth of planning, design and development go to waste because the startup's owner thought he could do his own marketing by sharing links on friends' Facebook walls and tweeting with #hashtags.
Needless to say, his beautiful site sits there to this day, never having made a penny.
5. Hire Specialists, and Then Leave Them Alone
The greatest mistake I have seen startup entrepreneurs make is trying to do it all by themselves.
You have a unique set of strengths, skills and talents.
You may have good communication skills and an amiable personality that make you great at selling things.
Or maybe you have great PR connections, making you perfect to lead the marketing effort.
But do not try to be a one-person rock band. You cannot play guitar, bass, drums, and the keyboards all at the same time.
Hire professionals who can share the workload and "thoughtload."
Then, leave them alone.
I know, this company is your beloved brain-child, but micromanaging never helped anyone, least of all the micromanager.
You will lose your temper, your sleep and probably your mind in seeking to ensure that everything from that blasted name to the shade of blue is exactly as you envisioned it. I mention visual elements because they pose the greatest temptation to split hairs on and add your own personal touch to.
But, as any designer will tell you, the fastest way to slow productivity and decrease quality is to throw the wrench of "constructive criticism" right in the middle of someone's workflow.
The designer knows what they are doing. (I'm sure Mona Lisa looked pretty awful while ol' Leonardo was still painting her.)
If you've hired correctly, then your designer will have participated in many projects and will have a sense of professional duty, coupled with a personal drive to see you succeed. They will present you with something that looks awesome.
And, don't worry, you'll have the benefit of final approval on everything and be able to give feedback once they have a solid concept to show you. This way, you will no doubt like the work a lot more, get a lot more sleep, and have a lot more time for other cool stuff.
[Source of thumbnail image: "cohdra_100_3798.JPG"]

subset: commoncrawl


text:
I alluded to a change in my interests and focus in my last post. Some of you knew it was photography, others were concerned something was wrong. I just want to assure you I'm well and happy.
in the past couple of years, I've become fascinated (obsessed?) with photography and the arts community and I'm happy to share news I received this morning that my photo (left) won First Prize in the "Americana"-themed contest at the Delray Center for the Arts.
It came with this message:
"Congratulations to Joan Nova, Winner of the July Photo Contest "Americana". Joan's image is beautifully composed with a soft, evocative color palate and skillful use of window light."
[This photo was taken a couple of years ago in the Yesteryear Village exhibit at the Florida State Fair.]


text:
"Are you okay???"
I had never heard Indy sound so concerned for someone, and as I turned around to see who was hurt, my mind ran through the possibilities. There were four of us left from the larger party that had been out at White Rocks that day, now finishing up at a less traveled block of cliffs just over from the main area. One of my group had just been belaying me from the ground, while two others watched from a blocky ramp that projected from the side of the beautiful quartzite face.
Had my belayer rolled an ankle on the uneven ground? No, he looked okay.
Had someone on the ramp fallen off or been bitten by a rattler catching the late afternoon sun? Why was there blood dripping from my glasses?
"You got hit by a rock."
With my body still riding the adrenaline from the climb I had just finished, I didn't notice that a softball sized rock had glanced off my head as I looked down to check my footing or start untying my knot. Still not convinced it had happened, I put my hand to my scalp and could feel the blood filling my hair.
"Keep your hand there and try to slow the bleeding until we can take a look."
Grateful for the direction, I pressed down on my scalp (why didn't this hurt?) while John Kelbel untied me from the rope and helped me to a seat. As Indy lowered the first aid kit to us, I noted again how disturbing okay I felt. Not just free of pain, but coherent and not feeling even remotely dizzy or faint.
"Head wounds bleed a lot," they told me. It was a fact that I found oddly reassuring, but with a mile hike out and an hour drive home ahead of me, I would take any reassurance I could get. I also knew that calmness was the key, and calmness would come from relinquishing my control of the situation and leaving myself in their hands. If something like this had to happen, those were good hands to be in.
They patched me up, belayed me back up the hill in case dizziness took me, and by the time we got back to the cars they were comfortable enough with my functioning to let me drive home if Indy followed behind me. An hour later, he turned me over to Emily and we went down the road to the urgent care to get me checked out. No concussion, no skull fractures, still calm enough that my pulse rate set off the alarms on the machine, and only two stitches needed.
I was lucky.
I've said this a few times in the past week, but this was really an ideal kind of accident to have. With a rock of that size, the smallest change of position could have drastically altered the outcome, and yet here I am a week later typing this on my deck with only the itchiness of a healing cut to remind me that it happened. Scary enough to get my attention, but with the right people there to guide me through it, and minor enough that I can get back out and apply the lessons I learned while they're still fresh in my mind.
On the off chance those lessons will help anyone else, here are the three biggest:
1) Head wounds bleed a lot. It looks scary, but it's normal, so stay calm and do something about it.
2) Put pressure on the wound to stop the bleeding. Probably the first thing we learn in any first aid class, but in the moment I still had to be reminded to do it, and I'm glad there were people there to give me that reminder.
3) Wear a helmet! If you take nothing else out of this, wear a helmet. If I had been wearing one at the time, I wouldn't have any stitches in my head right now. So why wasn't I wearing one, especially when I had one with me? Because I had just come down from a toprope climb, and very few of us ever wear helmets on toprope. I can't even use the "helmets look stupid in photos" copout, since I was already wearing socks under my upturned climbing shoes when one of my partners was there for the sole purpose of taking guidebook photos. No, my lack of helmet had nothing to do with a misplaced sense of fashion, and everything to do with the complacency that arises when we think we've minimized the most likely dangers. Yes, helmets protect us when we fall, and falls resulting in head injury are unlikely on a toprope. But helmets also protect us from falling objects, and I should have remembered that an undeveloped rock face is likely to have loose pieces at the top that may be dislodged. Even on well-traveled cliffs, most climbing in Maryland is accessed from the top, meaning there are likely to be people above who may knock or throw all manner of objects over the edge. Please, if you're reading this, take my experience as a communal lesson and avoid learning it firsthand.
Stay safe out there!
Monday, June 20, 2016
Wake up call
3 comments:
- chirogirl said...
I'm so thankful you are ok, Robin. I really enjoy your blog. You have the gift. :)
- June 20, 2016 at 3:23 PM
- Alexander Yellen said...
Nice post. I have bookmarked you to check your new stuff.
First aid Maryland
Cpr class florida
- July 12, 2016 at 5:57 AM
- Clinton Bashir said...
First and foremost, I am happy that you are okay. This experience could have been far worse. Thank you for sharing you story. You have an excellent point about wearing proper safety gear. It's easy to not take this precaution seriously until you have an experience that reminds you to do so. I'll surely keep this in mind!
Clinton Bashir @ U.S. HealthWorks Spokane Valley
- July 21, 2016 at 5:36 AM


text:
The Accidental Trail Blazer
A collaboration between Yarra Trail and Fat Mum Slim.
WEARING: {me} Slim leg ponte pants & Long-sleeve blush print shirt / {Danielle} Faux fur vest, Multi stripe tee,
A few months ago, late last year to be more precise, an email popped into my inbox. It was one that equally confused me and excited me. It asked, 'Will you be one of our trail-blazers?'
First of all I thought it might be spam. Me? A trail blazer? Not really, right? And I think I wrote those exact words in reply. They then wrote back and listed all the people that they were putting in their trail-blazing team. There were brain surgeons, business owners, scientists, super successful people, and then me. ME.
And they told me why. It was all about creating a life that I loved, and paving the space in blogging. When I thought about it, I felt proud. Yarra Trail had picked a whole bunch of empowering and inspiring women to be part of their campaign, and I was beyond honoured to be part of it. {That's me and Danielle of Two Birds Brewing above}. I flew down to Melbourne, met with some of the women, and did a photo shoot as well {one of the scariest things I've done, which happened to turn in to one of the most fun things I've done ironically!} .People often ask about my blogging journey, and how I created this business, so I feel like it's a story I tell often but I don't think it's one I've shared here… so I thought I would today, along with some of the photos from the shoot.
WEARING: Meteor print dress
I come from a very normal family. My mum spent most of her years being mum to myself and my three siblings, and my dad has always been a salesman. We always had enough, but never too much. Most of all, we were just happy. My parents had very little rules, and very little expectations. They weren't strict and didn't push us when it came to school work, but somehow my siblings and I always had a drive to do our best.
I was always an A-grade nerd who tried her best, yet also happened to hang out in the cool gang. I learned to read and write early, and each year at school I was award the most proficient in class. I was always striving for the best, and I don't even know where that came from, it was just something inside me.
In my later years of high school, we were asked to decide on a career. I honestly had no idea what I wanted to do or be. I felt overwhelmed with the huge task of deciding my future. I flipped through a careers book, selected Advertising Account Executive, knowing very little about what it meant, but that it pleased my teacher that I'd made a decision and I left it at that.
I scored the marks to make it into University, so I enrolled because it seemed like the right thing to do. I was just going through the motions… until I fell sick with a mystery illness. I couldn't walk more than 10 steps. I had to sleep downstairs in the lounge room of my family's home because I couldn't make it up the stairs. I needed help for someone to bathe me. I was a mystery to doctors, and a misery to myself. It was horrible not knowing what was wrong with me, and frightening not knowing how on earth I'd get better, or even when.
I missed the chance to go to University so had to defer. I lay in that bed for weeks, losing 15kg because I couldn't eat {the only real perk of the whole ordeal}. It was when I started to feel better, that I started to wonder what I'd do with my life; and I decided that I wanted to be a nanny {temporarily until I could go to University the following year}.
I moved from the South Coast of New South Wales to Sydney and became a Nanny. I loved it. I more than loved it. I love the everyday joy in taking care of children, and the freedom that my job allowed. I got to spend my days playing and having fun, and actually get paid for it. I was excited about going to work each day, and in love with the fact that each day was different and fun. My job felt meaningful, and fulfilling.
It was from working as a nanny that I knew that I only wanted to do work that made me happy. Life was too short to do anything less.
WEARING: Zip trim roll neck top
It was only recently that my mum shared that others were concerned with my 'career' choice. Many had said to my parents, "What a waste for Chantelle! She's too smart to be a nanny."
Perhaps it was true, but I was also too smart to be cooped up in an office going to a job I hated each day. I knew it wasn't for me.
Fast forward 12 years and I gave birth to my first daughter, Lacey. I was getting very little sleep, taking her to work with me as a nanny, and craving something more. It seemed crazy because I was exhausted and time poor, but I wanted something for myself… so I started a blog. It was a private space to inspire me to lose my baby weight, and to share stories of parenting and sleep deprivation. I had no grand plans, or strategy. Honestly, I thought it'd be something that I'd probably write in once or twice, and then forget about.
WEARING: Slim leg ponte pants & Long-sleeve stripe shirt
Instead I found a brand new passion. I loved writing, I loved sharing, and most of all I loved connecting with people all over the world. I was one of the first of my friends to have kids, so I had very few people to share the new mum journey with… but with a blog, I had people all over the world going through exactly the same thing. I was far from alone.
It was in those early days that a new me was created; the blogger. Over the years I wrote feverishly. Sometimes I wrote twice a day, others every other day. I loved it. It wasn't a career, but a hobby. No one was making money blogging. It was just me pouring my heart out to the internet.
And then an email came in. An editor of a huge parenting website loved my work and wanted me to contribute to their site. Enter the hustle. I worked full-time as a nanny to four kids, while dragging Lacey along to work with me. I was still being woken around 6 times a night by my baby girl, and on top of that I was working 20 hours a week at Kidspot, and maintaining my blog. It was the hustle of all hustles, but I've never been afraid of hard work.
For months I kept it up, until I realised that the children I was nannying would grow and no longer need me, and that writing and blogging could potentially have legs and create a new career for me. So, I begged my editor to take me on full-time. I was so ballsy. I told her how much I needed to earn, I told her what I could do to build the business and I told her that they should hire me. Somehow it worked, they created a new role for me and it all began. Leaving nannying was heartbreaking, I cried a lot, but I knew I was making the right decision for my future.
I spent a few years doing the Kidspot hustle, and maintaining my blog, until 5 years ago I decided to work full-time on my blog. It was by far the scariest decision I've ever made. My husband I have always contributed equally to the bills, and I needed to keep that up. Hubby had his doubts that I could make it work, but I was ready to do the work I needed to do. So I took the leap. You know what they say, "Leap and the net will appear."
And the net did.
WEARING: Slim leg ponte pants {so comfortable!} & Long-sleeve blush print shirt
I've learned a lot over these past 9 years of blogging. It's been hard, and enjoyable at the same time. I've gone from not knowing how to run a business, to understanding how to read and negotiate contracts, and do all the accounting that a small business needs.
It was in those early days of nannying that I learned that life was too short to do work that you didn't love, and it's a lesson I've kept with me for life. We spend almost a third of our life at work, and I refuse to do something that doesn't bring me joy. So 'Seek Joy' has been my working motto.
Blogging has allowed me to juggle raising my babies, and to do work that I love and feel really passionate about, and if we're to believe the very kind people at Yarra Trail, to also be a Trail Blazer in the blogging space.
WEARING: Slim leg ponte pants & Long-sleeve blush print shirt
Shooting this campaign with Yarra Trail has been both an honour and a blast. What an honour, seriously! The team were beautiful to work with, and the clothing was so easy to wear and beautiful too. Getting in front of a camera makes me so nervous, but there I was. I'm kinda proud of myself.
You can see more inspiring, real women in the Yarra Trail campaign as they release more of the shoot over the coming months. You can also shop some of the current range by popping over here.
Do you love what you do? What's your best advice for younger self?


text:
About Us
IMCO Carbide Tool was founded in 1977 in the heart of the U.S. Midwest manufacturing belt.
Today we are recognized as leaders in advanced cutting tool technologies with distributors in North America, South America, Europe and the Pacific Rim. IMCO is headquartered along the I-75 industrial super-corridor, just minutes from the Ohio Turnpike (80/90 East-West) and I-75 (North-South).
IMCO tools are sourced and made in the U.S., with all the product and service integrity that implies.
Productivity is never an accident. It is always the result of a commitment to excellence, intelligent planning, and focused effort.- Paul J. Meyer


text:
HSBC Bank Bermuda Limited is committed to preserving the confidentiality of all personal data you provide to us. We have therefore adopted privacy principles as a critical component of our relationship with you. The following privacy principles apply:
Our website and Internet Banking services, along with most other major websites, may use cookies as a means of collecting non sensitive information on general website usage. Cookies are pieces of information that a website transfers to the cookie file on your computer's hard disk. Cookies enable users to navigate around the website and (where appropriate) enable us to tailor the content to fit the needs of visitors who have accessed the website.
These cookies are not designed to identify you personally and the information they gather is used only to guide improvements in navigation, enhance content and (where appropriate) enable us to tailor the content to fit the needs of visitors who have accessed our website. If you would like to browse our website you may do so without accepting cookies.
We use two types of cookies on our website, which are:
Cookies cannot look into your computer and obtain information about you or your family or read any material kept on your hard drive and, unless you have logged onto Internet Banking, cookies cannot be used to identify who you are. Cookies cannot be used by anyone else who has access to the computer to find out anything about you, other than the fact that someone using the computer has visited a certain website.
Cookies do not in any way compromise the security of Internet Banking. The web browsers of most computers are initially set up to accept cookies. If you prefer, you can set your web browser to disable cookies or to inform you when a website is attempting to add a cookie. You can also delete cookies that have previously been added to your computer's cookie file. You can set your browser to disable persistent cookies and/or session cookies but if you disable session cookies, although you will be able to view our public unsecured website, you will not be able to log onto Internet Banking. If the computer that you are using is set to disable persistent cookies, you will be able to access Internet Banking; however, your navigation of the website may be less enjoyable.
Also, in order to develop our website in line with customer needs, we use Adobe Analytics to track visitor numbers to our website. Adobe Analytics provides us with statistics to show which pages on our website are visited most frequently and how long visitors spend on our website.
Adobe Analytics uses cookies to track the number of unique users of our website informing us whether our website has a small number of regular visitors or a large number of infrequent visitors. None of the information can be traced to an individual. We do not know who you are as a unique user, merely that there are a certain number of people using our website. The cookie only relates to what goes on in our website and the information cannot be used for marketing on an individual basis.
The HSBC Bermuda website may contain electronic images, known as web beacons or spotlight tags. These enable HSBC to count users who have visited certain pages on our website. Web beacons and spotlight tags are simply tools used to obtain generic information about the web pages visited. They are not used to obtain information about specific users.


text:
Let's talk about S corporations.
There are two types of corporations: C corporations and S corporations. Think Amazon or Apple and we are talking about "C" corporations: they file their own returns and pay their own taxes. Think of family-owned Schmidt Studebaker Carriage & Livery and we are talking about "S" corporations: only so many shareholders, do not normally pay tax, the numbers flow-through to the owners who pay the tax on their personal returns.
S corporations are almost the default tax structure for entrepreneurial and family-owned businesses, although in recent years LLCs have been giving them a run for their money. They are popular because the owner pays tax only once (normally), as contrasted to a C corporation with its two levels of tax.
But there are rules to observe.
For example, you have to keep track of your basis in your stock - that is, the amount of after-tax money you have invested in the stock. Your basis goes up as you put the business income on your personal return, but it also goes down as you take distributions (the S equivalent of dividends) from the company. You are allowed to take distributions tax-free as long as your basis does not go negative. Why? Because you paid tax on the business income, meaning you can take it out without a second tax.
Accountants keep permanent schedules to track this stuff. Or rather, they should. I have been involved in more than one reconstruction project over the years. You have to present these schedules upon IRS audit.
I did not previously have a worse-case story to tell. Now I do. The best part is that the story takes place in Cincinnati.
Gregory Power is a commercial real estate broker with offices first on Montgomery Road and then on Hosbrook Road. He started his company (Power Realty Advisors, Inc.) in 1993. Somewhen in there he used Quicken for his accounting, and he would forward selected reports to his accountant for preparation of the returns.
COMMENT: Quicken is basically a check-register program. It tracks deposits and withdrawals, but it is not a general ledger - that is, the norm for a set of business books. It will not track your inventory or depreciable assets or uncollected invoices, for example.
There was chop in the preparation. For example, the numbers were separated between those Mr. Power reported as a proprietor (Schedule C) and those reported on the S return. Why? Who knows, but it created an accounting problem that would come back to haunt.
He lost money over several years, including the following selected years:
1995 (191,044)
1996 ( 70,325)
2002 ( 99,813)
Nice thing about the S corporation as that he got to put these losses on his personal return. To the extent his return went negative, he had a net operating loss (NOL) which he could carry-over to another year. Mind you, he got to put those losses on his personal return to the extent he did not run out of basis - yet another reason to maintain permanent schedules.
He took distributions. In fact, he took distributions rather than taking a salary, which is a tax no-no. The IRS did not come after him on this issue because it had another angle of attack.
He had the corporation pay some of his personal and living expenses, which is another no-no. Accountants will reclassify these to distributions and tell you to stop.
Some of his S corporation returns did not show distributions. This is not possible, of course, as he was taking distributions rather than salary. That tells me that the accountant did not have numbers. It also tells me the accountant could not maintain the schedules - at least not accurately - that we talked about.
Sure enough, his big payday years came. There was tax to pay ... except for those NOLs that he was carrying-forward from his bad years. He told the IRS that he had over $500,000 of NOLs, which he could now put to good use.
Problem: He did not have those schedules.
Solution: He or his accountant went back and reconstructed those schedules.
Problem: The IRS said they were bogus.
Solution: You go to Tax Court.
COMMENT: It would have been cheaper to keep schedules all along.
Mr. Power ran into a very severe issue with the Court: it does not have to accept your tax returns as proof of the numbers. The Court can request the underlying books and records: the journals, ledger and what-not that constitutes the accounting for a business.
The Court did so request.
He trotted out those Quicken reports and handwritten summaries.
The Court noted that Mr. Power was somehow splitting numbers between his proprietorship and the corporation, although it did not understand how he was doing so. This made it difficult for the Court to review a carryforward schedule when the Court could not first figure-out where the numbers for a given year were coming from.
Strike one.
The Court wanted to know what to do with those tax returns that did not show distributions, which it knew was wrong as he was taking distributions rather than a salary.
Strike two.
And there was the matter of personal expenses being paid through the company. It appears that in some years the corporation deducted these expenses, and in other years it did not. The Court wasn't even sure what the amounts were. It did not help when Mr. Power commingled business and personal funds when buying his house in Indian Hill.
Strike three.
His business accounting was so bad that the Court bounced the NOL carryforward. The whole thing.
He owed tax. He owed penalties.
And no one knows if he really had an NOL that he could use to sop-up his profitable years because he had neglected his accounting to an extreme degree. He could not prove his own numbers.
But Mr. Power has attained tax fame.


text:
I colored with my ProMarkers, then die cut it with one of my Sue Wilson dies. I made the background by cutting black CS with a die from Memory Box. It's a stitched die but that's hard to see in the photo. The delicate circles are a separate die, also by Memory Box, and those were cut from a scrap bit of CS which was on the desk.
I used a bit of scrap, blue ribbon from my stash and added the burlap butterfly. The critter himself defined the sentiment which is cut by hand. Who can resist a cute little guy like that bringing flowers to his lady?
Art Impressions
Aud Sentiments
Crafting with an Attitude
Crafty Addicts
Crafty Calendar
Crafty Ribbons
Creative Moments
Lemon Shortbread
Tuesday Throwdown
Word Art Wednesday
Work It Wednesday
Short post this morning but it's very late (or very early depending on how you look at the middle of the night!) and I have appointments in the morning so I need some sleep. Happy Stamping. NanaConnie
Please continue to leave comments. The "Word Verification" really isn't on. BLOGGER INSISTS ON SHOWING THE "CAPTCHA" ICON BUT IF YOU IGNORE IT AND JUST PUBLISH YOUR COMMENT, IT WILL POST JUST FINE. I WISH I COULD GET RID OF IT BUT THERE'S NO OPTION FOR THAT WHEN THE COMMENTS ARE WRITTEN IN A SEPARATE BOX. SORRY.


text:
Pacific Pipeline Supply was established in 1987 on the foundation of exceptional service at the local level to Water Agencies and Contractors that service the underground pipeline industry. Although this industry is dominated by multi-branch, mega-corporations, or "big-box stores," Pacific Pipeline Supply has continued to grow and prosper, servicing their customers with high quality personal service.
Combine the well over 100 years of employee experience and add exceptional and innovative products for Water, Reclaimed Water, Sewer, Storm Drain, and Fire Protection Systems and the result is a supplier that will make "The Difference."
"Old Fashioned Service…at Hot Rod Speed" is not just our slogan, but our combined effort to offer our customers the good service of years gone by with today's speed and technology.
We Know Waterworks
Pacific Pipeline Supply began by focusing on Waterworks needs throughout San Diego County focusing on Water, Sewer, and Fire Protection. As the Waterworks industry has expanded, so has Pacific Pipeline's product base and our service area. We now offer complete lines in Recycled Water and Stormwater needs as both industries have gone from fledgling markets to driving forces in Southern California.
As market and environmental changes occur, like here in Southern California, your suppliers must also adapt. The recycled water industry is growing at rapid pace as California gets more creative with water resources. We now offer everything from Purple PVC pipe, to Purple Valves, Hydrants, Coated Copper, etc. For more info see our Recycled Water Page in our Products section.
Our Storm Drainage line has seen a similar boon as developers and land owners are forced to manage Stormwater runoff. Our Premier Storm Drainage product line is Prinsco HDPE Dual Wall Pipe and Fittings. This material has helped move, store, and manage Stormwater economically and efficiently, espeically with the use of HDPE Detention Systems. Detention systems are exponentially growing in demand to manage Storm Runoff and prevent flooding along with safety and health risks. See our Storm Drain Page in our Products section for more info.
About Pacific Pipeline Supply
Pacific Pipeline Supply is the only independent, local family-owned and operated waterworks company in San Diego County. Although this industry is dominated by multi-branch, mega-corporations located in other states, Pacific Pipeline Supply has continued to grow and prosper, servicing their customers with high quality personal service.Our company maintains three separate facilities in San Marcos, California, which house the largest and most complete inventory of piping products. Our employees offer a combine the well over 100 of waterworks experience.


text: In the late 1960s, the American artist Robert Smithson coined the term "land art". Works are not simply placed outdoors, but created as part of nature and the landscape. One of the proponents of this movement, James Turrell, even turned an entire volcano in Arizona into an art installation. which brings us to the southern island of Kyushu with its 30 active and inactive volcanoes.


text:
Today we're putting Shyla Colt's boxed set, Ride: Dueling Devils, in the spotlight with an excerpt. She's also got a very nice giveaway, so don't miss it!
Experience the Ride from the beginning.
The red, white, and blue rally used to be a high point for Ardy Larkin. The festival brought in enough money for the town to scrape by, and added a bit of excitement to the air. This year everything's different. Her father made a deal he couldn't back, and now her life is forfeit. Demanded as payment for their debt she finds herself attached to the biggest, baddest, member of the Dueling Devils M.C., their president, Demon.
In need of someone to watch his children while he was away, Ardy Larkin seemed like the perfect solution to all Demon's problems, until he caught a case of feelings for an innocent girl who didn't belong in his world. When a dangerous situation forces his feeling to the forefront, he shows her what it means to be claimed by a member of the Dueling Devils.
Book 2: Payback
She paid the price for her family's debt working for the Dueling Devils M.C. Love was never meant to be part of the deal. But somehow, the dark and dangerous club president, Demon stole her heart. Now she's thrust into hell fire. The Sidewinders' personal attack on Demon's family has the M.C. out for blood. As the rough side of Demon's lifestyle rears its ugly head, she's tested to her breaking point.
Consumed with keeping his family safe, Demon is determined to put the Sidewinders in the ground. Focused on revenge, he watches the miles between him and Ardy grow. The. M.C. comes first, but he won't let Ardy walk away now that he's claimed her. Backed into a corner he does the only thing he knows how to, fight his way out.
Book 3: Wrecked
You can't have love without trust, so Lefty never looked twice at a woman. Betrayed at a young age, the only people he trusts are his brothers in the Dueling Devils motorcycle club. The boys took him in and showed him the meaning of family and loyalty. Then he broke his own rule and slept with the same woman more than once. She became a habit, and he got ensnared by the island beauty who ruled her strip club with an iron fist. The problem is, Gia's not interested in anything serious.
The minute Gia Hughes began to trust Lefty, she knew she was in too deep. The smart thing would've been to walk away, but the chemistry between them was too powerful. Then he started asking for more, and she was forced to run from the only thing she ever really wanted—a place to belong. The skeletons buried in her closet need to stay buried to keep her safe, but all too soon that decision is taken out of her hands.
"Close down the shop and head home early, okay?" Shocked, she stared at him, rooted to the spot. They never closed early. "Ardy." The terse tone of her father's voice broke through her stupor.
"I'm on it, Da." She placed her towel in the dirty bucket they laundered daily, and stepped from behind the bar. The sensation of eyes on her back amplified with every step she took. Flipping the sign from open to closed, she turned the dead bolt.
"Thank you. Now, straight home," her father said.
"Oh no, I think she should stay." The husky voice made her belly bottom out like the tallest roaster coast at an amusement park. "Your failure to come through is going to affect her directly. I think she deserves to know about it up front."
She rotated slowly and faced the man effectively taking a wrecking ball to her life—Demon, the Dueling Devils' president. The sheer size of him intimidated her. At least six-foot-three with broad shoulders and a solid build, the man was massive. Bronze skin peeked out from beneath the mural of colorful tattoos that covered the thick muscles of his arm. Mesmerized by his magnetism, she moved her gaze up to his face. A square jaw, long, straight nose, and oval-shaped face gave him rugged beauty. His brown eyes held novels full of experience. He couldn't be much more than late thirties, but those eyes were wizened. Her mouth dried out, and her muscles tensed. What could he possibly want with me? Illustration of degradation, unwanted sexual advances, and submission danced behind her lids.
She'd seen the house mouses who didn't want to be where they ended up. Dead eyes, fake smiles, and strain were the things each one seemed to have in common. Demon focused in on her, and their gazes clashed. Like a snake trapped by the flute notes played by a charmer, she found herself unable to look away.
"What the hell does Ardy have to do with any of this?" Her father's chest heaved. He stood ramrod straight, clenching his hands, but his voice remained tempered. They had a lot riding on this. A show of the Larkins' infamous Irish temper wouldn't help a damn thing.
"We need to take this to the office." Demon nodded toward the double doors that lead to the small office in the back. "Refreshments for my boys?"
"Of course ." Her father nodded. "Ardy, stay here and serve them."
"No, she comes with us," Demon said.
The no-negotiable tone made her stomach clench. Blood rushed in her ears. Questions swirled in her head, swarming like a hive of agitated bees trying to protect their queen from danger. Overwhelmed, each thought felt fleeting, moving out of her grasp before she could get a handle on it. Panic dumbed her. Like a deer caught in headlights, she lost the ability to rationalize. The walk to the office was the longest of her life. Ushered into a chair by her father, she sat beside him on the opposite side of the desk from Demon.
"Do you want to tell me what you meant out there?" her father said.
"She's the payment I'll be collecting for your debt," Demon said.
Buy it now: Amazon
Here's the info on the giveaway!
Prize: a tour-wide giveaway for a $20 Amazon gift card
How to enter: Use the Rafflecopter link below
About the Author
Shyla Colt grew up in Cincinnati, Ohio, but has lived a variety of different places thanks to her wanderlust, interesting careers, and marriage to a United States Marine. She's always loved books and wrote her very first novel at the age of fifteen. She keeps a copy of her first submission letter on her desk for inspiration.
After a lifetime of traveling, she settled down and knew her time had come to write. Diving into her new career like she does everything else, with enthusiasm, research and a lot of prayers, she had her first book published in June of 2011. As a full-time writer, stay at home mother, and wife, there's never a dull moment in her household.
She weaves her tales in spare moments and the evenings with a cup of coffee or tea at her side and the characters in her head for company. A self-professed rebel with a pen. Her goal is to diversify romance as she continues to genre hop, and offer up strong female characters.
Connect with Shyla online: Website | Facebook | Twitter | Tumblr


text:
Hi! It's Kate from Kate's Kodaly Classroom. I have been a little bit absent from the blogging world recently, but am so glad to be back on the Kodaly Corner!
If you haven't read Karla's latest post for surviving the end of the year, make sure to check it out! There are so many great ideas and reminders for surviving the wonderful and incredibly chaotic time of year!
The end of the school year is one of my favorite times of year for so many reasons... kids and teachers are excited for summer vacation, celebrations are happening left and right, field days, performances, graduations... it really is a wonderful time. It is also around this time of the year that I make a conscious effort to reflect. I believe that reflection is one of the most important things we can do to grow and develop as teachers. I know that our schedules in May and June are JAM PACKED, but I truly believe an hour with a latte and a notebook can make a huge difference in your professional development and growth. So, for my post today, I am going to share with you some helpful hints for (drum roll, please!)...
Step One: Celebrate
Just about every teacher I know works incredibly hard all school year (and summer- let's be real) long. So, before you develop a list of "I could have" or "I wish I would have," take a few minutes to celebrate the "I did." Chances are you did A LOT of amazing things this school year- whether it was surviving your first year teaching, connecting with that one student that you struggled with, or finally cataloguing you choral library- so take a few minutes to celebrate your victories.
Ask yourself...
- What did I teach that my students loved?!
- What did I teach that I loved teaching?!
- Did I inspire or connect with a student or students in a new or meaningful way?
- Did I have have any great collaborations with colleagues? Parents? Community members?
- What went really well?
Step Two: Evaluate
If there is anything I have learned in my eight years of teaching, it is that we are learners first and teachers second. I continue to find new tricks and new ideas to use in my classroom on almost a daily basis! With the constant change, it's important to evaluate what is a "keeper" and what you might consider changing in the future.
As I reflect on the school year, I try to break it up into a few different areas. Here are some of the areas I try to give some thought to...
Concepts and Instruction
- What concepts did I teach really well?
- Are there any holes in my instruction or sequencing?
- What concepts do I need to spend more time/effort on?
- Do I need to develop any manipulatives or teaching materials?
- Were there any activities that my students respond well to? Any that they didn't?
- Which performances went well? Which didn't?
- Did I have enough time to prepare for performances?
- Were there any themes/programs I want to keep? Any I want to change?
- How did my performance schedule work? Were any times of the year TOO busy? Can I make any adjustments?
Personal Goals
- What did I improve on as a teacher this year?
- What professional development/professional learning was really meaningful?
- What kinds of professional development and growth do I want to pursue in the future?
- How did I handle my life/work balance? Did I use time wisely? Could any of my effort be better spent elsewhere?
Being honest in assessing your school year is a great way to prioritize your goals looking forward. Which leads me to the last step in my process...
Step Three: Look Forward
I could probably write a 100 page list of things I would like to improve on as a teacher. It's easy to get overwhelmed or even disheartened by the never-ending "to-do" list. So, I really try to set achievable and reasonable goals for myself. I find that this helps to keep me motivated and inspired throughout the year, and it also feels really great to be able to check something off the list.
Here are some ideas of ways you can keep it simple, but still set meaningful goals...
- Find one concept or unit you want to improve on. Build up your song library for that concept, make a set of post-office or other manipulatives that you can use to teach it, develop an assessment or find a great worksheet you can use during your teaching.
- Create one professional growth goal. Whether it be improving your knowledge/use of technology, attending more workshops, or finally creating a library of all your children's books, come up with one goal you think you can achieve in the coming school year.
- Fix one problem. Teaching is definitely trial and error. No matter how much we plan, there are bound to be things that don't go well. See if you can identify one problem from this school year that you can correct next year.
At the beginning of each school year, I write a list of "hopes and dreams." Sometimes, it is as simple as "leave before 5:00 more" or "give at least one student a day personalized feedback" and sometimes they are bigger things like "finish all my rhythmic flashcard sets" or "learn and include more folk dances in my instruction." I love the feeling at the end of year when I can say "I did it" and ask myself "what's next?!"
During the insanity that is the end of the year, try to find a few minutes to go grab a latte or a lemonade and reflect. I promise it is time well spent.


text:
Hinweis: der Artikel stammt im Original von integralzen.org und wird in Kürze ins Deutsche übersetzt!
At Integral Zen, we use the zazen, kinhin, and koans from traditional Rinzai Zen. We also use the Five Training Elements and the transformative practice of Mondo Zen to re-orient, mature and enlighten our ego and our emotional bodies. In addition to these, we add the conceptual framework of Integral Theory and more rigorous forms of individual and collective psychological shadow work.
With Integral language and a deep meditative practice, we are able to discuss complex topics with greater understanding, clarity, and compassion. By using Ken Wilber's Integral Theory, including his AQAL map – all levels, lines, types, states, and quadrants – the territory of our lives comes alive.
This map allows greater compassion for ourselves and others, since it empowers us to stop imposing our unconscious assumptions about the world onto nearly every place we touch it. And yet, the map is not the territory, and Integral Zen is ruthless in its distinction between intellectual understanding, experiential understanding, and spiritual insight.
Meditative practitioners with deep spiritual insight often suffer from a too-partial view of the cosmos. Integralists with sophisticated maps of the world often suffer from a lack of experiential insight about the true nature of their minds.
The complexity of an evolutionary, 21st Century spirituality cannot be understood without a common language. An Integral View, combined with a stable spiritual insight, greatly enhances the level of clarity, predictability, and understanding within our community. We are able to more profoundly connect with ourselves and each other.
We understand our own Zen practice through an empowering yet humbling lens that allows us to understand better what we have realized, and what we have yet to discover.
Integral Zen and Personal and Collective Psychological Shadow
The process of awakening is the very process of making what is unconscious, conscious. But we cannot enlighten the parts of our mind that we cannot see, no matter how deep our spiritual insight or how vast our intellectual knowledge.
You can be deeply awake or a great scholar, and still be a reactive and petty jerk in your own life! In our experience, a person's ability to fully awaken is directly tied to his or her ability and willingness to face psychological shadow material. If you're human you have it, without exception.
Integral Zen recognizes that each one of us has aspects of his or herself that are undeveloped, no matter the depth of spiritual insight. Within the unique paths that have led us to where we are, there are steps that are often missed. Therefore we examine what steps were missed in our own development. We then choose to consciously make room for and encourage each other to develop in these specific areas.
Integral Zen includes many forms of psychological shadow work to illuminate our disowned and false selves. When we disown part of ourselves we automatically create a lie, a story about who we are that is not true. This is what Jung called the persona, Voice Dialogue calls the primary self, and Wilber calls the false self. When this shadow, the disowned self, is reintegrated into the personality, there is no need to continue to lie to ourselves. The false self is seen through, discarded and replaced with a more authentic sense of self that includes the disowned parts.


text:
Tamoxifen is the generic version of Nolvadex and is basically a medication that performs as an antagonist of estrogen receptors within the breast tissue. It is the medication that is widely used for the prevention of breast cancer as well as the hormonal treatment for early breast cancer. The main reason why these patients buy tamoxifen and use it in treating breast cancer only is because this type of cancer needs estrogen in order to grow and these estrogens bind with estrogen receptors and activates them. What tamoxifen does is that it gets metabolized into compounds and binds itself with estrogen receptors as well but does not activate them. Additionally, tamoxifen helps in preventing estrogen from binding onto the same receptors, thus blocking the growth of the cancer.
ICI Pharmaceuticals (now named AstraZeneca) discovered tamoxifen. Although the drug is mostly known for being used in treating breast cancer, both for pre- and post-menopausal women, there are actually other types of treatments, people buy tamoxifen for:
Infertility – some women are prescribed to buy tamoxifen in order to treat their infertility. Tamoxifen 20-40mg per day for five days is given during the 3rd to 7th day of a woman's cycle. Aside from this, tamoxifen is given for treat a rare condition called retroperitoneal fibrosis.
Bipolar Disorder – some patients are prescribed to buy tamoxifen in order to treat the mania of those with bipolar disorder through the blocking of the protein kinase C, which is basically an enzyme that is responsible for regulating neural activity within the brain.
Gynecomastia – one of the more common uses on why men buy tamoxifen is through the prevention of gynecomastia. Of course, not all men who develops gynecomastia are recommended to take tamoxifen as only men who are into body building, particularly those who are taking anabolic steroids are inclined into taking tamoxifen. The reason as to why they buy tamoxifen and use it is because when they are currently into the cycle of their steroid use, their body has lowered levels of estrogen. However, once they are put off their steroid cycle, the body will begin try to compensate with the low levels of estrogen by producing more. Such high levels of additional estrogen within the body means that all the work they have done building muscle mass will be lost. Basically, what tamoxifen does is that it inhibits water retention, thus preventing excess water weight within the chest muscles.
Cancer and Angiogenesis – women buy tamoxifen for its anti-breast cancer properties and early breast cancer treatment capacity. Tamoxifen is actually one of only three drugs that is considered as anti-angiogenetic which prevents the development or growth of new blood vessels – a condition that plays a very important role towards the development of cancer. It was a research named Dr. Judah Folkman who actually discovered angiogenesis and how it plays an important role on the development of cancer. This discovery actually helped researchers isolate and make inhibitor drugs that can prevent angiogenesis. What makes tamoxifen useful in the treatment of cancer of the breast is that it prevents the estrogen from binding to receptors because the compound in itself does that.


text:
Packed with heart-healthy fat and spices, you will find yourself craving this crunchy cucumber snack over your usual junk food. For more digestion-friendly foods, check out nutritionist J.J. Smith's 10-Day Tummy Tox recipes.
- 1 cucumber, sliced
- 1 tbsp olive oil
- Juice of 1 lemon wedge
- cayenne pepper
1. Cut cucumber into slices. Toss with the rest of ingredients in a bowl and serve.
RatingThis recipe has not been rated
Tried this recipe? Log in to DoctorOz.com to rate it and find more recipes just for you.
RatingThis recipe has not been rated
Tried this recipe? Share your rating below!


text:
- Research article
- Open Access
- Open Peer Review
Interleukin-22 is elevated in lavage from patients with lung cancer and other pulmonary diseases
- Amanda Tufman1, 5Email author,
- Rudolf Maria Huber1, 5,
- Stefanie Völk2, 5,
- Frederic Aigner1,
- Martin Edelmann1, 5,
- Fernando Gamarra1, 5,
- Rosemarie Kiefl1, 5,
- Kathrin Kahnert1, 5,
- Fei Tian1, 5,
- Anne-Laure Boulesteix3,
- Stefan Endres†2, 5 and
- Sebastian Kobold†2, 4, 5Email author
© Tufman et al. 2016
- Received: 6 November 2014
- Accepted: 28 June 2016
- Published: 7 July 2016
Interleukin-22 (IL-22) is involved in lung diseases such as pneumonia, asthma and lung cancer. Lavage mirrors the local environment, and may provide insights into the presence and role of IL-22 in patients.
Bronchoscopic lavage (BL) samples (n = 195, including bronchoalveolar lavage and bronchial washings) were analysed for IL-22 using an enzyme-linked immunosorbent assay. Clinical characteristics and parameters from lavage and serum were correlated with lavage IL-22 concentrations.
IL-22 was higher in lavage from patients with lung disease than in controls (38.0 vs 15.3 pg/ml, p < 0.001). Patients with pneumonia and lung cancer had the highest concentrations (48.9 and 33.0 pg/ml, p = 0.009 and p < 0.001, respectively). IL-22 concentration did not correlate with systemic inflammation. IL-22 concentrations did not relate to any of the analysed cell types in BL indicating a potential mixed contribution of different cell populations to IL-22 production.
Lavage IL-22 concentrations are high in patients with lung cancer but do not correlate with systemic inflammation, thus suggesting that lavage IL-22 may be related to the underlying malignancy. Our results suggest that lavage may represent a distinct compartment where the role of IL-22 in thoracic malignancies can be studied.
- Bronchoalveolar lavage
- Interleukin-22
- Biomarker
- Lung cancer
- Pneumonia
Interleukin-22 (IL-22) is a cytokine from the interleukin-10 family which acts exclusively on IL22-receptor-1 (IL-22-R1) positive epithelial and endothelial cells [1]. In the lung IL-22 has been shown to be expressed by T cells, natural killer-cells, macrophages, epithelial and potentially also by tumour cells [2]. Its effects can be both immunoregulatory and proinflammatory depending on the stage of disease [3, 4]. IL-22 seems to be protective in the acute phases of lung inflammation or injury such as pneumonia, fungal infection, traumatic lung injury, acute lung injury associated with pancreatitis or the initial phase of allergic airway inflammation [4–8]. In acute inflammation, IL-22 recruits inflammatory cells to clear the infection, probably through the local upregulation of chemokines in the lung, and to rescue lung epithelial cells from cell death [5, 9]. However, if the pathological condition is not cleared and the inflammation becomes chronic, IL-22 seems to sustain inflammation and contribute to the disease phenotype [3, 10]. Recently, we and others have found evidence for IL-22 as a mediator in the interaction between lung cancer cells and the immune environment [11]. In vitro IL-22 promotes tumour growth and chemotherapy resistance of lung cancer cells. Analysis of a large cohort of patients suffering from lung cancer has revealed that IL-22 is frequently expressed in lung cancer tissue, but the clinical significance of these findings has yet to be addressed [12]. In addition, we previously measured IL-22 serum levels in lung cancer patients and matched healthy controls but did not find any difference in spite of strong tissue expression [12]. These observations prompted us to hypothesise that the systemic circulation may not adequately reflect processes in the lung, and that a closer analysis of the pulmonary compartment may help to better understand the role of IL-22 in lung cancer.
In the present study, we analysed lavage specimens from 195 consecutive patients (37 with lung cancer) undergoing clinically indicated bronchoscopy and correlated IL-22 expression with local and systemic cell counts and with serum markers of inflammation.
Study protocol
Patients underwent routine diagnostic or therapeutic flexible bronchoscopy in the Respiratory Medicine and Thoracic Oncology Section of the Internal Medicine Department V, Ludwig Maximilians University of Munich, Germany. Bronchoscopy was carried out under conscious sedation following written informed consent. Bronchoalveolar lavage and bronchial washings, described here together as bronchoscopic lavage (BL), were carried out as indicated, in most cases for diagnostic cytological, pathological or microbiological evaluation. The decision to perform bronchoalveolar lavage vs. washings was at the discretion of the responsible physician. Excess lavage material was used for IL-22 analysis. Patient samples and data were anonymised. Technicians performing the analyses were blinded to all clinical information including patient diagnosis. The study and its protocol were approved by the local ethics board (Ethikkommission der Universität München, decision number EK 376-11).
Patients and samples
Lavage interleukin-22 concentration in clinically characterized cohorts
Number of patients (% of study cohort)
IL-22 [pg/ml] (median)
Number of samples above DL
83 (44 %)
111 (57 %)
Age (years)
Pulmonary Infection
49 (25 %)
Lung Cancer
37 (19 %)
Thoracic manisfestation of non-lung cancer
14 (7 %)
Other lung diseases
79 (41 %)
Reference cohort
22 (11 %)
Lavage samples and routine analysis
Bronchoalveolar lavage and bronchial washings were collected and analysed according to standard operating procedures at our centre, which are reviewed regularly and are in line with published protocols [13] and indications [14, 15]. In brief, following local anesthesia patients were sedated and intubated nasally with a flexible bronchoscope. For bronchoalveolar lavage the bronchoscope was advanced into wedge position preferentially in the right middle lobe. Normal saline was instilled in 20 ml aliquots to a total volume of 120 to 160 ml and was retrieved using suction. For bronchial washings the bronchoscope was introduced into the area of clinical interest (in most cases the segment thought to be affected by infection or tumour) and normal saline (generally 40 to 80 ml) was instilled and retrieved using suction. A standard morphological and immunologic analysis of BAL cellular components was performed and included total cell count, differential count of macrophages, lymphocytes and neutrophils as well as flow cytometry analysis of the lymphocyte subsets, including BAL CD4/CD8 T-cell ratio. Differential cell count (leukocytes, lymphocytes, neutrophils, macrophages and CD4/CD8 ratio) subgroups were based on accepted cut-off values used for the interpretation of BAL fluid. Bacterial cultures and cytological analyses were performed as clinically indicated at institutes affiliated with the Ludwig-Maximilians Universität in Munich. Analysis of blood samples was performed as part of the routine diagnostic work up at the discretion of the treating physician and in line with national recommendations [16].
Enzyme-linked immunosorbent assay (ELISA)
ELISA for IL-22 detection was obtained from R&D, Abington, UK. In brief, 50 μl of diluted samples (in triplicates) were loaded and incubated for 2 h at room temperature (RT). Detection antibody was applied for 2 h at RT and streptavidin-bound horseradish peroxidase (HRP) was added for 20 min at RT. Absorption was measured at 450 nm using a Mithras reader (Berthold Technologies, Bad Wildbad, Germany). The detection limit of the ELISA was 15 pg/ml.
Statistics and data analysis
For the IL-22 levels, mean values of three independent experiments each performed in triplicates were calculated and used for subsequent analysis. The differences in IL-22 levels between two independent groups were assessed using the two-part Wilcoxon test [17], in which the values below the detection threshold 15 were set to 0. Similarly, correlations between IL-22 levels and other continuous variables (CRP, leucocytes, lymphocytes, neutrophiles, macrophages, eosinophiles, CD4/CD8) were assessed using Spearman's rank-based correlation test with values of Interleukin-22 below 15 set to 0. P-values < 0.05 were considered as significant. Statistical analyses were performed using R 3.0.2.
Samples from patients with lung cancer suffering from chronic obstructive pulmonary disease (COPD) or lung infection were excluded from the comparative analysis with the control cohort and correlation with clinical parameters to avoid bias in the IL-22 concentrations due to causes other than lung cancer (n = 16, 45 %).
IL-22 is elevated in bronchoscopic lavage from patients with lung cancer
IL-22 does not correlate with systemic inflammation
Correlation of IL-22 concentrations in lavage with systemic inflammation parameters in samples from patients with pneumonia or lung cancer. Leucocyte subpopulations were not measured in all patients. Correlation was analyzed using Spearman's rank-based correlation test after setting all IL-22 values <15 to 0
Correlation of IL-22 in lavage with markers of systemic inflammation
Subgroup size (n)
p-value for correlation
Patients with Lung Cancer
Correlation of IL-22 in BL with CRP
Correlation of IL-22 in BL with Leucocytes
Correlation of IL-22 in BL with Lymphocytes
Correlation of IL-22 in BL with Neutrophils
Patients with Pneumonia
Correlation of IL-22 in BL with CRP
Correlation of IL-22 in BL with Leucocytes
Correlation of IL-22 in BL with Lymphocytes
Correlation of IL-22 in BL with Neutrophils
IL-22 is not associated with a particular cell type in lavage from patients with lung cancer or pneumonia
Correlation of IL-22 concentrations in lavage with distinct cell populations in the lavage samples of patients with pneumonia or lung cancer. Not all lavage cell populations were measured in all patients. Correlation was analyzed using Spearman's rank-based correlation test after setting all IL-22 values <15 to 0
Correlation of IL-22 in lavage with cell populations in lavage
Subgroup size (n)
p-value for correlation
Patients with Lung Cancer
Correlation of IL-22 in BL with BL Lymphocytes
Correlation of IL-22 in BL with BL Macrophages
Correlation of IL-22 in BL with BL Neutrophils
Correlation of IL-22 in BL with BL Eosinophils
Correlation of IL-22 in BL with BL CD4/CD8 ratio
Patients with Pneumonia
Correlation of IL-22 in BL with BL Lymphocytes
Correlation of IL-22 in BL with BL Macrophages
Correlation of IL-22 in BL with BL Neutrophils
Correlation of IL-22 in BL with Eosinophils
Correlation of IL-22 in BL with BL CD4/CD8 ratio
The present study demonstrates that IL-22 concentration in pulmonary lavage samples can be quantified using ELISA and that the levels of IL-22 in lavage vary between different disease entities. Patients with bacterial pneumonia, lung cancer or pulmonary manifestations of other tumours appear to have higher levels of IL-22 in lavage samples compared with non-lung disease controls. In patients with lung cancer, IL-22 levels in lavage did not correlate with systemic signs of inflammation. We found that within the lung, IL-22 may originate from different cell populations.
The finding that patients with NSCLC show higher levels of IL-22 in pulmonary lavage specimens is in line with the results of a previous study reporting that lung cancer cells may produce IL-22 [11]: Zhang and colleagues found high expression of IL-22 in primary tumour tissue, serum, and malignant pleural effusion of NSCLC patients, as well as expression of the IL-22 receptor (IL-22-R1) on lung cancer cell lines. We recently studied the expression of IL-22 in tissue microarray samples of a large cohort of lung cancer patients and found IL-22 expression mostly in patients with large cell NSCLC and those with small cell lung cancer 22 [12]. The lung cancer patient cohort in the present study is, however, too small to confirm these histological subgroup results. In the present study, we did not detect IL-22 in BAL samples from some of the lung cancer patients studied. While technical reasons may be put forward to explain these results, levels of IL-22 may vary significantly between tumor patients. Low levels of IL-22 may be of prognostic relevance, as IL-22 is thought to promote a more aggressive lung cancer phenotype [12].
To the best of our knowledge, the present study is the first to investigate IL-22 concentrations in pulmonary lavage from cancer patients and show that IL-22 is elevated in lavage samples from lung cancer patients. It thus strengthens the hypothesis that IL-22 has a role in lung cancer. The elevated IL-22 levels found in patients with pulmonary manifestations of extrathoracic tumours support the hypothesis that IL-22 may be a mediator in cancer development and progression [18].
In addition to the data we have presented, IL-22 has been investigated in other non-malignant lung diseases. A recent study in pulmonary lavage samples from patients with bronchial asthma revealed that IL-22 concentrations are elevated, further supporting that IL-22 is a disease-associated cytokine detectable in lavage and associated with lung inflammation, as seen in our study [19]. Studies on the host response towards bacterial or fungal pneumonia have revealed that IL-22 contributes both to the acute phase, where it supports clearance, and to the chronic phase, where is prolongs inflammation. In chronic infections such as tuberculosis, IL-22 seems to play a disease promoting role [20]. Our study detected higher levels of IL-22 in lavage samples from patients with pneumonia compared to controls, supporting the suggestion that IL-22 plays a role in the pulmonary response to infection. This is in line with previously published data which identified IL-22 producing cells in BAL from patients with pneumonia [21]. Recently, IL-22 has been detected in lavage samples from patients with community-acquired pneumonia and correlated with serum levels of IL-22, corroborating our finding that IL-22 is associated with pulmonary inflammation [21].
In the lung, IL-22 is thought to be mainly produced by lymphoid cells, among others by CD4-positive lymphocytes [5, 22, 23]. In previous studies analysing lavage samples in patients with tuberculosis, T helper cells were identified as the major source of IL-22 production in BAL [22]. However, in our current study, we did not find any association between IL-22 production, and lymphocytes found in lavage from patients with pneumonia and the number of patients with lung cancer was too low to draw firm conclusions from the analysis with CD4 to CD8 T cell ratio. While T cells as source of IL-22 in lung cancer have not been proposed prior to our study, our data are supported by evidence from other tumor types such as colon, gastric or hepatic carcinomas where CD4 T cells are thought to be the main sources of IL-22 [24–26]. In contrast, in lung cancer, the source of IL-22 remains uncertain. One study has proposed that IL-22 is expressed by the tumor cells themselves [11]; however, an earlier study from our group was not able to confirm these results, supporting the notion that IL-22 is expressed in the environment but not in the tumor cells themselves [12]. This idea is promoted by a recent study analysing IL-22 producing cells in malignant pleural effusions which identified CD4 T cells as major source [27]. Our study may point towards a role for different cell populations rather than an individual one as source of IL-22 in the lung, as we found no clear correlation between IL-22 and the analysed cell populations. However, the current study was not powered to prove a lack of association between cell populations and IL-22 in the lung.
A noteworthy finding of the present study is the dissociation between local IL-22 concentrations and systemic parameters of inflammation such as CRP and leukocyte counts in patients with lung cancer. This suggests that IL-22 in the lavage of lung cancer patients reflects local processes in the lung rather than systemic inflammation. The concept of the airway as a distinct biological compartment with cytokine levels differing from those in the systemic circulation is supported by other studies: Hollander et al. [28] found that the concentrations of IL-8 and of other markers of inflammation were significantly higher in BAL samples compared to serum samples in patients with bronchial asthma and COPD.
Lavage is a clinically useful tool in the diagnostic evaluation of many patients with pulmonary disease and malignancy; however, clinicians must consider the limitations of this technique when interpreting results. The sensitivity of lavage cytology for lung cancer is reported to be 48 %, lower than that of brushings or endobronchial biopsy [29]. Biomarkers in lavage have the potential to improve the sensitivity of this minimally invasive method in lung cancer diagnosis. Techniques to increase the concentration of IL-22 in lavage samples, such as the use of small volume lavage or lavage catheters placed near the tumor, may further increase the diagnostic sensitivity.
IL-22 can be measured in lavage samples, and correlates with the presence of lung disease. Lavage IL-22 concentrations are highest in patients with pneumonia and lung cancer. IL-22 in lavage does not significantly correlate with systemic inflammation. IL-22 concentrations were not significantly associated with a particular cell population found in the lavage, indicating that IL-22 production may arise from different sources. Our results suggest that IL-22 in pulmonary lavage may serve as a marker for lung cancer, and, perhaps, for pulmonary metastases of other tumours. Markers expressed in the pulmonary compartment can be sampled using bronchoscopic lavage, and may mirror local disease states.
The authors acknowledge and thank the funding sources listed above.
This work was supported in parts by the international doctoral program "i-Target: Immunotargeting of cancer" funded by the Elite Network of Bavaria (to SK and SE), the Marie-Slodowska-Curie Innovative Training Network "IMMUTRAIN: Training Network for the Immunotherapy of Cancer" funded by the H2020 program of the European Union (to SK and SE), the Melanoma Research Alliance (to SK and SE), the Wilhelm Sander Stiftung (grant number 2014.018.1 to SE and SK), the Graduiertenkolleg 1202 "Oligonucleotides in cell biology and therapy" funded by the Deutsche Forschungsgemeinschaft (to SK and SE), the Else-Kröner-Fresenius Stiftung (to SK), the Ernst-Jung-Stiftung (to SK) and the German Cancer Aid (to SK). Parts of this work have been performed for the doctoral theses of AT, SV and FA at the Ludwig-Maximilians Universität München.
Availability of data and material
A summary of the datasets supporting the conclusions of this article is included within the article. Individual patient data sets will not be published; however, cohort data sets may be requested from the corresponding authors.
Authors' contributions
AT wrote the manuscript, conceived the study, contributed to study design, carried out biomaterial analyses, collected and characterized samples, analysed the results, and contributed to the final manuscript; RMH wrote the manuscript, conceived the study, contributed to study design, carried out biomaterial analyses, collected and characterized samples, analysed the results, and contributed to the final manuscript; SV carried out biomaterial analyses, analyzed the results, contributed to the final manuscript; FA collected and characterized samples, analysed the results, and contributed to the final manuscript; ME collected and characterized samples, analyzed the results, contributed to the final manuscript; FG collected and characterized samples, analyzed the results, contributed to the final manuscript; RK carried out biomaterial analyses, analyzed the results, contributed to the final manuscript; KS carried out biomaterial analyses, collected and characterized samples, contributed to the final manuscript; FT carried out biomaterial analyses, analyzed the results, contributed to the final manuscript; ALB analyzed the data, designed the figures and contributed to the final manuscript. SE wrote the manuscript, conceived the study, contributed to study design, and contributed to the final manuscript; SK wrote the manuscript, conceived the study, contributed to study design, carried out biomaterial analyses, collected and characterized samples, analysed the results, and contributed to the final manuscript. All authors read and approved the final manuscript.
Competing interests
The authors declare that they have no competing interests.
Consent for publication
Not applicable. Individual patient data and images are not presented in this manuscript.
Ethics approval and consent to participate
The study and its protocol were approved by the local ethics board of the University of Munich (Ethikkommission der Universität München, decision number EK 376-11). All patients gave written informed consent prior to bronchoscopy. No animal experiments were performed during the study.
Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
Authors' Affiliations
- Vivier E, Spits H, Cupedo T. Interleukin-22-producing innate immune cells: new players in mucosal immunity and tissue repair? Nat Rev Immunol. 2009;9(4):229–34.View ArticlePubMedGoogle Scholar
- Whittington HA, Armstrong L, Uppington KM, Millar AB. Interleukin-22: a potential immunomodulatory molecule in the lung. Am J Respir Cell Mol Biol. 2004;31(2):220–6.View ArticlePubMedGoogle Scholar
- Lilly LM, Gessner MA, Dunaway CW, et al. The beta-glucan receptor dectin-1 promotes lung immunopathology during fungal allergy via IL-22. J Immunol. 2012;189(7):3653–60.View ArticlePubMedPubMed CentralGoogle Scholar
- Gessner MA, Werner JL, Lilly LM, et al. Dectin-1-dependent interleukin-22 contributes to early innate lung defense against Aspergillus fumigatus. Infect Immun. 2012;80(1):410–7.View ArticlePubMedPubMed CentralGoogle Scholar
- Simonian PL, Wehrmann F, Roark CL, et al. Gammadelta T cells protect against lung fibrosis via IL-22. J Exp Med. 2010;207(10):2239–53.View ArticlePubMedPubMed CentralGoogle Scholar
- Huai JP, Sun XC, Chen MJ, et al. Melatonin attenuates acute pancreatitis-associated lung injury in rats by modulating interleukin 22. World J Gastroenterol. 2012;18(36):5122–8.View ArticlePubMedPubMed CentralGoogle Scholar
- Hoegl S, Bachmann M, Scheiermann P, et al. Protective properties of inhaled IL-22 in a model of ventilator-induced lung injury. Am J Respir Cell Mol Biol. 2011;44(3):369–76.View ArticlePubMedGoogle Scholar
- Aujla SJ, Chan YR, Zheng M, et al. IL-22 mediates mucosal host defense against Gram-negative bacterial pneumonia. Nat Med. 2008;14(3):275–81.View ArticlePubMedPubMed CentralGoogle Scholar
- Besnard AG, Sabat R, Dumoutier L, et al. Dual role of IL-22 in allergic airway inflammation and its cross-talk with IL-17A. Am J Respir Crit Care Med. 2011;183(9):1153–63.View ArticlePubMedGoogle Scholar
- Paats MS, Bergen IM, Hanselaar WE, et al. Local and systemic cytokine profiles in non-severe and severe community-acquired pneumonia. Eur Respir J. 2013;41(6):1378–85.View ArticlePubMedGoogle Scholar
- Zhang W, Chen Y, Wei H, et al. Antiapoptotic activity of autocrine interleukin-22 and therapeutic effects of interleukin-22-small interfering RNA on human lung cancer xenografts. Clin Cancer Res. 2008;14(20):6432–9.View ArticlePubMedGoogle Scholar
- Kobold S, Volk S, Clauditz T, et al. Interleukin-22 is frequently expressed in small- and large-cell lung cancer and promotes growth in chemotherapy-resistant cancer cells. J Thorac Oncol. 2013;8(8):1032–42.View ArticlePubMedGoogle Scholar
- Baughman RP. Technical aspects of bronchoalveolar lavage: recommendations for a standard procedure. Semin Respir Crit Care Med. 2007;28(5):475–85.View ArticlePubMedGoogle Scholar
- Meyer KC, Raghu G. Bronchoalveolar lavage for the evaluation of interstitial lung disease: is it clinically useful? Eur Respir J. 2011;38(4):761–9.View ArticlePubMedGoogle Scholar
- Meyer KC. Bronchoalveolar lavage as a diagnostic tool. Semin Respir Crit Care Med. 2007;28(5):546–60.View ArticlePubMedGoogle Scholar
- Hoffken G, Lorenz J, Kern W, et al. Epidemiology, diagnosis, antimicrobial therapy and management of community-acquired pneumonia and lower respiratory tract infections in adults. Guidelines of the Paul-Ehrlich-Society for Chemotherapy, the German Respiratory Society, the German Society for Infectiology and the Competence Network CAPNETZ Germany. Pneumologie. 2009;63(10):e1–68.View ArticlePubMedGoogle Scholar
- Lachenbruch PA. Comparisons of two-part models with competitors. Stat Med. 2001;20(8):1215–34.View ArticlePubMedGoogle Scholar
- Huber S, Gagliani N, Zenewicz LA, et al. IL-22BP is regulated by the inflammasome and modulates tumorigenesis in the intestine. Nature. 2012;491(7423):259–63.View ArticlePubMedPubMed CentralGoogle Scholar
- Pennino D, Bhavsar PK, Effner R, et al. IL-22 suppresses IFN-gamma-mediated lung inflammation in asthmatic patients. J Allergy Clin Immunol. 2013;131(2):562–70.View ArticlePubMedGoogle Scholar
- Yao S, Huang D, Chen CY, et al. Differentiation, distribution and gammadelta T cell-driven regulation of IL-22-producing T cells in tuberculosis. PLoS Pathog. 2010;6:2.View ArticleGoogle Scholar
- Paats MS, Bergen IM, Hanselaar WE, et al. T helper 17 cells are involved in the local and systemic inflammatory response in community-acquired pneumonia. Thorax. 2013;68(5):468–74.View ArticlePubMedGoogle Scholar
- Scriba TJ, Kalsdorf B, Abrahams DA, et al. Distinct, specific IL-17- and IL-22-producing CD4+ T cell subsets contribute to the human anti-mycobacterial immune response. J Immunol. 2008;180(3):1962–70.View ArticlePubMedPubMed CentralGoogle Scholar
- Ten Berge B, Paats MS, Bergen IM, et al. Increased IL-17A expression in granulomas and in circulating memory T cells in sarcoidosis. Rheumatology. 2012;51(1):37–46.View ArticlePubMedGoogle Scholar
- Liu T et al. Increased circulating Th22 and Th17 cells are associated with tumor progression and patient survival in human gastric cancer. J Clin Immunol. 2012;32(6):1332–9.View ArticlePubMedGoogle Scholar
- Kuang DM et al. B7-H1-expressing antigen-presenting cells mediate polarization of protumorigenic Th22 subsets. J Clin Invest. 2014;124(10):4657–67.View ArticlePubMedPubMed CentralGoogle Scholar
- Kryczek I et al. IL-22(+)CD4(+) T cells promote colorectal cancer stemness via STAT3 transcription factor activation and induction of the methyltransferase DOT1L. Immunity. 2014;40(5):772–84.View ArticlePubMedPubMed CentralGoogle Scholar
- Ye ZJ et al. Interleukin 22-producing CD4+ T cells in malignant pleural effusion. Cancer Lett. 2012;326(1):23–32.View ArticlePubMedGoogle Scholar
- Hollander C, Sitkauskiene B, Sakalauskas R, Westin U, Janciauskiene SM. Serum and bronchial lavage fluid concentrations of IL-8, SLPI, sCD14 and sICAM-1 in patients with COPD and asthma. Respir Med. 2007;101(9):947–53.View ArticleGoogle Scholar
- Schreiber G, McCrory DC. Performance characteristics of different modalities for diagnosis of suspected lung cancer: summary of published evidence. Chest. 2003;123(1 Suppl):115S–28.View ArticlePubMedGoogle Scholar


text:
"True Valor" Garners Award for Uncommon Heroes Series
- Multnomah Publishers
- 2003 26 Jun
Multnomah Publishers fiction author Dee Henderson has won the 2003 Virginia Romance Writer's of America's Holt Medallion award for Long Inspirational.
"True Valor" is the second book in Henderson's Uncommon Heroes series, and spent five consecutive months on the CBA Fiction Bestseller list in 2002.
Dee Henderson is the bestselling author of the O'Malley series of romantic suspense novels, and the Uncommon Heroes series of military romance novels. Three of her books have been nominated for awards in 2003.
"True Honor" (book three in the Uncommon Heroes series) is a finalist for the 2003 ECPA Gold Medallion Fiction Award, and both "True Honor" and "The Healer" are finalists for the 2003 Christy Award for Romance. Three of her titles were nominated for the Holt Medallion, with "True Valor" as the chosen winner.
"True Valor" is a suspenseful romantic thriller. In "True Valor," Major Bruce "Striker" Stanton, Air Force Pararescue Jumper, spends his life rescuing pilots downed behind enemy lines. Lieutenant Grace "Gracie" Yates spends hers flying an F/A-18 Hornet for the Navy. Separated by overseas deployment orders, they exchanged love letters. But when Gracie is shot down behind enemy lines, Bruce has one mission: get Gracie out alive.
Courtesy of Multnomah Publishers


text:
Thursday, March 3, 2011
Savina Purple Hologram
24 comments:
So pretty :) http://rachlovesleopardprint.blogspot.com/ReplyDelete
- SuzanneMMarch 3, 2011 at 7:47 AM
So pretty and subtle! Loving the new tips and tricks up top too ;) xReplyDelete
Ohhh I think I love this :PReplyDelete
Thanks you guys!! It really is soooo pretty up close!!ReplyDelete
Suzanne, oh good!! I really hope it is able to help some :)
Very feminine. :)ReplyDelete
Wow, this looks very unique. Not completely sure if I like it, but I definitely like it that you show stuff other people don´t show.ReplyDelete
i love this colour, it looks beautiful in your nails!ReplyDelete
wow.. the color is totally awesome.ReplyDelete
So pretty and sweet:)ReplyDelete
- Cammy YloMarch 3, 2011 at 4:53 PM
It reminds me of a ballerina's tutu! : DReplyDelete
very cute polish! Quick Question!-ReplyDelete
do you ever leave on your nail poilsh degins for like a week or so
cuz everyday you change it
you never leave the degins dont you get tired of
changing it everyday
---- just wondering
this reminds me of a raspberry yogurt.. I love it! Can I put in a request for another scotch tape mani? :)ReplyDelete
I love that you can see the glitter, and it's not buried. I have a few Savina colors and am quite pleased with them!ReplyDelete
This polish looks gorgeous, I love it.ReplyDelete
o wow, soooooooooo pretty! makes me think of a creamy cupcake or something! lolReplyDelete
Thanks you guys!!!ReplyDelete
Heidi, haha, umm....I actually change about 2-3 times a day, eeekkk. The only time I will leave a mani on, is if I'm going out somewhere, but the next morning it's off, hahaha.
Monkey, you sure can and I will try to get one up tomorrow or the next day :)
Gotham, this is actaully my first and I ordered a couple more. I really like their formula. I can't wait to get them!
I love this color!ReplyDelete
Thanks girlie!ReplyDelete
This is really pretty! And very girly! Its so cute!ReplyDelete
- AnonymousApril 2, 2011 at 1:05 AM
Super pretty!!!...I've purchased this brand from Nordstrom Rack before...i wonder if they have this color!! :)ReplyDelete
Oh I have no idea, I didn't even know Nordstrom sold this brand! I might have to check this out!ReplyDelete
Thanks for theReplyDelete
Click here
Click here
Click here
Click here
Click here
Click here
سعودي انحراف
شات عسلي
سعودي كول
شات صوتي
وكذلكً يتم استخدام الكثير من المعدات الحديثة والمميزة وذلك ما يجعلها من أفضَل المؤسسات الرائدة في ميدان نقل وفك وتركيب الأثاث ونقله من موضع إلى موضع أخر على نحو لين وسريع وأكثر دقة.ReplyDelete
شركة نقل عفش
شركة نقل عفش من الرياض الى الاردن
شركة نقل اثاث من الرياض الى الاردن
شركة نقل عفش بمكة


text:
- 31 -
BIOS Setup
BIOS (Basic Input and Output System) records hardware parameters of the system in the CMOS on the
motherboard. Its major functions include conducting the Power-On Self-Test (POST) during system startup,
saving system parameters and loading operating system, etc. BIOS includes a BIOS Setup program that
allows the user to modify basic system configuration settings or to activate certain system features. When
the power is turned off, the battery on the motherboard supplies the necessary power to the CMOS to keep
the configuration values in the CMOS.
To access the BIOS Setup program, press the <Delete> key during the POST when the power is turned on.
To see more advanced BIOS Setup menu options, you can press <Ctrl> + <F1> in the main menu of the
BIOS Setup program.
To upgrade the BIOS, use either the GIGABYTE Q-Flash or @BIOS utility.
• Q-Flash allows the user to quickly and easily upgrade or back up BIOS without entering the operating
• @BIOS is a Windows-based utility that searches and downloads the latest version of BIOS from the
Internet and updates the BIOS.
For instructions on using the Q-Flash and @BIOS utilities, refer to Chapter 4, "BIOS Update Utilities."
Chapter 2 BIOS Setup
• Because BIOS flashing is potentially risky, if you do not encounter problems using the current
version of BIOS, it is recommended that you not flash the BIOS. To flash the BIOS, do it with
caution. Inadequate BIOS flashing may result in system malfunction.
• BIOS will emit a beep code during the POST. Refer to Chapter 5, "Troubleshooting," for the beep
codes description.
• It is recommended that you not alter the default settings (unless you need to) to prevent system
instability or other unexpected results. Inadequately altering the settings may result in system's
failure to boot. If this occurs, try to clear the CMOS values and reset the board to default values.
(Refer to the "Load Optimized Defaults" section in this chapter or introductions of the clearing
CMOS jumper/battery in Chapter 1 for how to clear the CMOS values.)
Document Outline
- Box Contents
- Optional Items
- GA-H55M-D2H/GA-H55M-S2H Motherboard Layout
- GA-H55M-D2H/GA-H55M-S2H Motherboard Block Diagram
- Chapter 1 Hardware Installation
- 1-1 Installation Precautions
- 1-2 Product Specifications
- 1-3 Installing the CPU and CPU Cooler
- 1-4 Installing the Memory
- 1-5 Installing an Expansion Card
- 1-6 Back Panel Connectors
- 1-7 Internal Connectors
- Chapter 2 BIOS Setup
- 2-1 Startup Screen
- 2-2 The Main Menu
- 2-3 MB Intelligent Tweaker(M.I.T.)
- 2-4 Standard CMOS Features
- 2-5 Advanced BIOS Features
- 2-6 Integrated Peripherals
- 2-7 Power Management Setup
- 2-8 PC Health Status
- 2-9 Load Fail-Safe Defaults
- 2-10 Load Optimized Defaults
- 2-11 Set Supervisor/User Password
- 2-12 Save & Exit Setup
- 2-13 Exit Without Saving
- Chapter 3 Drivers Installation
- Chapter 4 Unique Features
- Chapter 5 Appendix


text:
All work and no play makes Jack a dull boy
New Work All Play
The project centred around a lasercut projection mapped head which was live streamed to a website where you could interact with it via Twitter. We asked people to adjust our adapted 'All workand no play makes Jack a dull boy' meme with their own take on work and play. The head then pushed these words through a thesaurus API and created a unique job title for you along with some fancy graphics.
Why the work and play meme? The project was created to promote theManchester International Festival and one of the sponsors Bruntwood. Bruntwood are a big player in the office space market in Manchester and MIF are known for creating lots of unique new work. So creatively we started with 'work' and 'play' – hijacking the meme made a lot of sense.


text: Terms of Use Privacy Policy Hide Sports Commentary 30 Things Not Even Football Fans Like About Football Season 30 Things Not Even Football Fans Like About Football Season 30 Things Not Even Football Fans Like About Football Season Over-Crowded Bars Thursday Night Games Losing Your Bets Losing To The Auto-Draft Guy Text-Fighting During A Game Overly Angry Fans Overly Nerdy Fans Admitting You Like Frank Caliendo Commentators Saying "The National Football League" Hypocritical Comments From Commentators Joe Buck And Troy Aikman All The Money You'll Spend Gaining Weight Defending Liking Sports Defending Liking Fantasy Sports The New NFL Penalties Realizing The NFL Doesn't Really Care About Player Safety NFL Purses Johnny Manziel Stories Buying Team Merch You Don't Need Realizing Your Friend Is A Jerk London Games Fox NFL Robot Overdose On Beer Commercials The Player Who Never Gets Great Your New Nickname Will Not Be Popular Skip Bayless And Stephen A. Smith That Boring Monday Night Football Game The Agony Of Defeat Post-Season Depression Defending Liking Sports Neal Stastny September 3, 2014 Share Tweet Flip 0 Shares Many people love sports, but many people don't. Get ready to listen to an argument for the thousandth time about how you're cheering for jock millionaires who don't care about you. It's a stupid argument, but it happens every year. Just find out anything that person likes (politics, movies, etc.), point out the millionaires that create it and ask that person if they care about them personally. Prev Next Recommended Reading Fine Living News Get Scientific About Your NFL Fantasy Draft With This App Power & Money News Trending News: This Awful Campaign Ad Is Actually Really Insulting To Men Health & Sports News Trending News: Donald Trump Says Colin Kaepernick Is Why The NFL's Ratings Suck Entertainment News Trending News: Is Quidditch Tougher Than Football? Richard Sherman Has The Answer Health & Sports News Trending News: Here's How Much You Should Spend On Your Next NFL Tailgate


text:
Matthew 6:25-34
Birds were created to fly. No one had to tell them. When the time is right, the mamma bird picks the baby up and drops it and they fly. I'm sure there is no discussion in the nest, no "wait Mom, take him first"; "Wait I'm afraid" or "I want to just hang out here a little longer". The Creator created them to fly; they're birds.
Humans were created to have a relationship with God. There's a deep unfulfilled longing in us that at first, we don't know what it is but as we grow we become more and more aware that there is something missing in our lives. We attempt to fill that void with all kinds of things – money, food, people, etc. When we do figure out what's missing – a relationship with God – we should then begin to know the One so intimately acquainted with us. He gave us the Bible for that reason.
He tells us He will provide for us, show us how to live lives pleasing to Him. Through His word, He attempts to direct us into the abundant life that's possible if we stay close to Him. We make that so complicated. We decipher and try to figure everything out on our own. We fret about anything that gets in our way when the truth is, if we would just simplify and believe, things wouldn't get so confusing and messed up.
Birds don't count their feathers and check their wings before taking off, they just spread them and go. Just fly, little birdie. The Lord Jesus simply says:
"Look. I created you for this. Just fly. Do what you were meant to do: fly. Don't consider anything, just do it."
The same is true for us. He created us. He knows every single hair on our heads. He knows our struggles and our circumstances. More importantly, He is with us through our circumstances and struggles. He simply says:
"Don't worry". I know it's scary and I know life is hard. I know it doesn't make sense but consider the birds. They don't give a thought to what they're going to eat, drink or wear; you shouldn't either. Didn't I say I would provide your needs? Why do you fret then? Why do you doubt? Just believe me and keep going. Don't stop. Don't waste your time being fearful and trying to figure things out. I got this. I got you. Now fly!"
Whatever has you hostage, break free with trust in your heart that the Lord will see you through. You were meant for this, because this thing that troubles you will show someone else who God is. Just fly!