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Megadeth is an American heavy metal band from Los Angeles, California which was formed in 1983 by guitarist/vocalist Dave Mustaine, bassist Dave Ellefson and guitarist Greg Handevidt, following Mustaine's expulsion from Metallica. The band has since released 13 studio albums. A pioneer of the American thrash metal movement, Megadeth rose to international fame in the 1980s and was ranked as one of the "Big Four of Thrash" along with Metallica, Slayer and Anthrax, who were responsible for creating, developing and popularizing the thrash metal sub-genre.
Over the band's 28 active years, over 20 different people have officially performed as part of the group, with Mustaine being the only constant member. Megadeth is known for its distinctive, technical instrumental style that often features dense, intricate passages and trade-off guitar solos. Megadeth is also known for recurring lyrical themes including politics, war, addiction, personal relationships, and religion. Megadeth has sold over 30 million albums worldwide with five consecutive albums being certified platinum or multi-platinum in the US. As of 2012, Megadeth has received ten Grammy nominations.
Website: http://www.megadeth.com
Location: Los Angeles, California
Members: 7
Latest Activity: Sep 11, 2011
Early days (1983–1984)
Dave Mustaine Dave Ellefson
Dave Mustaine (left) and Dave Ellefson (right) founded Megadeth in 1983.
Dave Mustaine was originally a member of Metallica upon their formation in 1981, but was fired from the band due to drinking, drug use, violent behavior and personality conflicts with James Hetfield, Lars Ulrich, and original Metallica bassist Ron McGovney. Two months after being fired, Mustaine and bassist Dave Ellefson formed Megadeth in Los Angeles. Mustaine later said, "After getting fired from Metallica, all I remember is that I wanted blood. Theirs. I wanted to be faster and heavier than them."
According to Mustaine, the name Megadeth represents the annihilation of power, while in itself is a corruption of the term megadeath. In order to upstage his former band, Dave Mustaine wrote more aggressive compositions,increasing tempos and altered aspects of songs such as "Mechanix", which Metallica's new line-up adapted into the slower-paced "The Four Horsemen". After unsuccessfully searching for a vocalist for nearly six months, Mustaine was convinced by bassist David Ellefson to handle lead vocal duties himself, while also serving as the band's primary lyricist, songwriter, co-lead and rhythm guitarists.
In 1984, Megadeth recorded a three song demo tape, referred to as the 1984 Demo, featuring Mustaine, Ellefson and drummer Lee Rausch. The demo contained early versions of "Last Rites/Loved to Death", "Skull Beneath the Skin", and "Mechanix". The band did a few live performances in 1984, before replacing Lee Rausch with fusion drummer Gar Samuelson.[9] Megadeth signed with the New York based independent label Combat Records. In December of that year, they added Chris Poland as a second guitarist.
Lyrical themes
As Megadeth's primary lyricist, Mustaine is known for his often controversial, political, and more recently, personal lyrics.War and nuclear war are common topics, including the military-industrial complex in songs such as "Architecture of Aggression", "Hangar 18", "Return to Hangar", and "Take No Prisoners", as well as the aftermath of war in songs such as "Dawn Patrol" and "Ashes In Your Mouth". The name Megadeth is a deliberate misspelling of the word megadeath, a term coined in 1953 by RAND military strategist Herman Kahn to describe one million deaths, popularized in his 1960 book On Thermonuclear War. Politics are also a common theme in Megadeth songs,as seen in Mustaine's scathing assessment of Tipper Gore, the PMRC, and music censorship in the song "Hook In Mouth". Mustaine takes an environmentalist stance in "Countdown to Extinction" and "Dawn Patrol",[123] and shows a general cynicism regarding politics in songs like "Symphony of Destruction", "Peace Sells",[13] "The World Needs A Hero" and "Blackmail the Universe". The UN is criticized for its ineffectiveness in "United Abominations" and "Peace Sells".
Controversial and misunderstood lyrics have also caused problems for the band. For instance, the music video for "In My Darkest Hour" was banned from MTV in 1988 when the music channel deemed the song to be pro-suicide.The music video for "À Tout le Monde" was later banned by MTV, also interpreted as being pro-suicide. According to Mustaine, the song was written from the perspective of a dying man, saying his last words to his loved ones.[40]
Addiction is also a common theme in songs such as "Use the Man", "Burnt Ice", and "Addicted to Chaos". "Use the Man" is about a former substance abuse counselor who died of a drug overdoses. Some lyrics have taken on overtly Christian themes, such as "Never Walk Alone... A Call to Arms", and "Shadow of Deth", with spoken lyrics taken directly from Psalm 23 of the King James Bible. "My Kingdom", "Looking Down The Cross" and "Of Mice And Men" also feature Christian themes.
Mustaine dabbled in black magic in his teenage years, which became the theme for the song "The Conjuring" off Peace Sells... but Who's Buying?. Mustaine stated that it was emotionally difficult to play because of his conversion to Christianity.
"I put two hexes on people, and they both worked and the result was just what I was asking for. Now, it took forever to get that Satanic depression off of me because it's just like playing with a Ouija board. You open the doorway to the dark side, and spirits come through. It took almost 20 years to get rid of that Satanic depression. I did it when I was 15, and I don't think I got free of it until I was in my mid-30s. You ask yourself, 'How is it possible that this is happening to me?' Well, because you flirted with the devil and you put a hex on somebody and you put another hex on somebody, and, well, you owe him. And that's why I have a problem playing 'The Conjuring' today."
—Dave Mustaine
Dave Mustaine is notorious for making inflammatory statements in the press, usually regarding feuds and problems with former Metallica bandmates or other bands, including Slayer, Suicidal Tendencies and Pantera. The oldest of these, and most well-known among fans, is Mustaine's long standing feud with Metallica members James Hetfield and in particular Lars Ulrich. This feud stemmed from his ejection from the band, the method with which it was conducted, and disagreements on songwriting credits. After more than two decades, this feud has been resolved and Mustaine and the members of Metallica are once again good friends.
In April 1988, at a concert in Antrim, Northern Ireland, Mustaine unknowingly dedicated the final song to the IRA.before the final song, "Anarchy in the UK", Mustaine said, "This one's for the cause!". Loyalists' took offense at this statement and a fight amongst the audience ensued. The band had to travel in a bulletproof bus for the remainder of the tour of Northern Ireland and the Republic of Ireland. Mustaine later alleged that he had been misled by T-shirt bootleggers about the meaning of the expression "the cause". This incident served as inspiration for the song "Holy Wars... The Punishment Due".
In July 2004, former bassist Dave Ellefson sued Mustaine for $18.5 million in Manhattan Federal Court. Ellefson alleged that Mustaine short changed him on profits and backed out of a deal to turn Megadeth over to him when they disbanded in 2002. Ellefson also accused Mustaine of locking him out of merchandise and publishing royalties. The suit was dismissed in 2005,and Mustaine filed a countersuit that was settled out of court.
In recent years,[when?] Dave Mustaine has become a born-again Christian. Following this, minor controversy was sparked by Mustaine's announcement that Megadeth will not play certain songs live anymore due to his new identification as a Christian.In May 2005, Mustaine also allegedly threatened to cancel shows in Greece and Israel with extreme metal bands Rotting Christ and Dissection due to the bands' anti-Christian beliefs. This caused the two bands to cancel their appearances.
Background information
Origin - Los Angeles, California, United States
Genres - Heavy metal, thrash metal, speed metal,hard rock
Years active -1983–2002, 2004–present
Labels - Roadrunner, Capitol, Combat
Associated acts -Metallica, F5, Panic, MD.45, Hail, Eidolon, Jag Panzer, Nevermore, Slayer, Anthrax, Soulfly
Current members
Dave Mustaine – lead vocals, rhythm & lead guitar (1983–2002, 2004–present)
Dave Ellefson – bass, backing vocals (1983–2002, 2010–present)
Chris Broderick – lead & rhythm guitar, backing vocals (2008–present)
Shawn Drover – drums (2004–present)
Killing Is My Business... and Business Is Good! (1985)
Peace Sells... but Who's Buying? (1986)
So Far, So Good... So What! (1988)
Rust in Peace (1990)
Countdown to Extinction (1992)
Youthanasia (1994)
Cryptic Writings (1997)
Risk (1999)
The World Needs a Hero (2001)
The System Has Failed (2004)
United Abominations (2007)
Endgame (2009)
Thirteen (2011)
This group does not have any discussions yet.
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My OEL 5.3 server with Oracle hasn't been behaving quite right lately, so all in all, the best choice at this time was to reinstall. At the same time, I wanted to redesign the disk / partition layout.
So here's a quick recap of this installation.
First, the OS.
- Downloaded OEL 5.4 64-bit CD's 1,2,3,4 and 6 from edelivery.oracle.com
- Booted from first disk, deleted all existing volume groups and selected two (out of six) disks to be available for the OS install.
- Disabled SELinux for the time being.
- Created the oracle OS user during OS installation.
(This server has no DVD player, and previous installations taught me that CD 5 wasn't necessary for me.)
(Which means Linux will put them together in one Volume Group.)
(To prevent some problems when configuring Oracle later, specifically "cannot restore segment prot after reloc" error.)
That went well enough, so now for some preparations.
- In one session: Transfer Oracle software to the new server:
rsync --progress linux.x64_11gR2_database_?of2.zip oracle@newserver:/src/
- In a parallell session: Set up Oracle public YUM server, courtesy of
- Install required packages:
yum install oracle-validated
- Create OS groups for oracle:
usermod -g oinstall -G dba oracle
- Make sure there is a line in the hosts file for the host itself, so the Oracle installer can map the hostname to an IP.
(Including mkdir /src and making oracle the owner of it.)
Create LVM volumes for the remaining disks; here are the commands used:
pvcreate /dev/sdc1 /dev/sdd1
pvcreate /dev/sde1 /dev/sdf1
vgcreate OracleVol01 /dev/sde1 /dev/sdd1
vgcreate OracleVol02 /dev/sdc1 /dev/sdf1
lvcreate -L 100G -n u01 OracleVol01
lvcreate -L 100G -n u02 OracleVol01
mke2fs -j /dev/OracleVol01/u01
mke2fs -j /dev/OracleVol01/u02
e2label /dev/OracleVol01/u01 u01
e2label /dev/OracleVol01/u02 u02
vi /etc/fstab
mkdir /u01
mkdir /u02
mount /u01
mount /u02
df -h
And then, install Oracle software, which is another story :)
sh /src/database/runInstaller

subset: commoncrawl


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Silkies.com coupon code May 2019 | promotional codes for Silkies.com
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I imagined my "comeback post" to feature a glorious FO that would excuse my long absence, but it's just not there yet. My recent purchase of a Nintendo wii has really taken a bite out of my knitting, blogging, and blog reading. Enough excuses.
But this little swing jacket from the latest Vogue is almost there! I've been withholding after my recent knitting mishaps, not wanting to disappoint or jinx this project. At this point, I'm feeling confident enough to share it. It's definitely not one for the frog pond. I just need to do some minor blocking and weave in about 200 ends. I think I really love it.
And moving on to the next thing:
I have had my eye on this sweater from Vogue's fall anniversary issue, and after seeing an awesome finished version by Nueroknits on ravelry, I decided to shop and swatch for it. I'm pretty excited about this swatch in terms of color and texture. This is sublime yarn's cashmere merino silk paired with their kid mohair blend.
New York seems to be warming up though, and at the slow pace I've been working, It'll be in the 70s if I finish this one. Luckily, all my wii remotes are out of battery power for the moment.
Thanks for all the great comments, because they totally make my day and encourage me to get my knit and blog on!
I'm off to Las Vegas tomorrow for a shoe tradeshow (yes, a shoe tradeshow. It happens twice a year). Wish me luck and happy thoughts of awesome shoes for fall 2008!
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Denny's Establishes New Five-Year $250MM Bank Credit Facility
Denny's Corporation announced that it has entered into a new five-year $250 million senior secured bank credit facility, comprised of a $190 million term loan and a $60 million revolving line of credit. The new facility refinances Denny's senior secured debt from September 2010 and amended in March 2011, which had a term loan originally in the amount of $250 million and a $60 million revolver.
Wells Fargo Securities, Regions Capital Markets, a division of Regions Bank, and GE Capital Markets are the joint lead arrangers and joint bookrunners with Wells Fargo Bank serving as administrative agent and L/C issuer and Cadence Bank and RBS Citizens serving as co-documentation agents.
The refinanced facility has a reduced interest rate of LIBOR plus 300 basis points for the term loan and revolver. This compares to the prior facility that had an interest rate of LIBOR plus 375 basis points, with a LIBOR floor of 1.50% for the term loan and no LIBOR floor for the revolver. The refinancing is expected to result in annualized interest expense savings of approximately $5 million (including approximately $4 million of annualized cash interest expense savings), based on current interest rates.
The term loan will be amortized 10% per year paid quarterly with the balance due at maturity. In addition, the Company will have the opportunity to further reduce interest rates and increase its flexibility for the use of cash by achieving lower leverage ratios. The company estimates that the closing of its new bank facility will result in a one-time charge to other non-operating expense of approximately $8 million in the second quarter of 2012, as a result of charges for the unamortized portion of deferred financing costs and original issue discount related to the prior facility, and portion of the fees related to the new facility.
John Miller, president and chief executive officer, stated, "Our new credit facility is a testament to the tremendous progress Denny's has made over the past several years with its franchise focused business model, resulting in a stronger balance sheet with growing profitability and free cash flow. In addition to reducing interest costs, this refinancing allows the company to further strengthen its balance sheet with more flexibility to create additional value for stockholders."
Denny's currently operates 1,685 franchised, licensed and company-owned restaurants across the United States, Canada, Costa Rica, Mexico, Honduras, Guam, Curacao, Puerto Rico and New Zealand.


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My Account Welcome visitor you can login or create an account.
+39 0000 000022 Call Us Monday - Saturday: 8:30 am - 6:00 pm
Delightfull Coltrane Pendant Lamp
Coltrane Pendant in Matte Black with Gold inside inspires a deep connection with the innovation and expression of Jazz music. Coltrane is a strong character piece which is simple yet effective. It draws your attention and adds a fine decorative element to a living, dining or foyer space. Adjustable in height, the two cables allow it to be hung at a number of different angles. Hang multiple pendants together to create a breathtaking feature.
Dimension: L1000mm x H600mm
Weight: 5kg
Body: Aluminum
Color: Black with Gold interior.
Tags: delightfull coltrane pendant lamp, delightfull lamp, coltrane lamp, hotel lamp, designer lamp.
Topson Lighting is a professional online distribution of high quality designer lighting,Modern & Contemporary Lighting,Scandinavian Lighting,Luxury Lighting.Browse and Free Shipping.


text: I'm a half-Turkish North Carolinian living in Brooklyn who loves making pictures and friends out of strangers. I started my career working for newspapers and then the NBA before co-founding Inspired Storytellers to use those skills to affect positive change through storytelling. My work has been exhibited at the MoMA and New York Public Library and has appeared in GQ, PDN Emerging Photographer, Sports Illustrated, Mashable, SLAM Magazine, Hoop Magazine, USA Today, NewYorkTimes.com, The Durham Herald-Sun, Indy Week and Time.com. I was also part of a team honored at Pictures of The Year International in 2015 for Tracing The Scars Of Katrina.


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to the distributor of:
HCS motors
to our shop 'rc-easy', dear visitor!
Our shop serves not only as a simple purchase forum but also as an information and service point.
You will be able to download technical data sheets and service manuals as well as software for upgrades etc.
Should you require further information about our service company, please enter your company name in our shop newsletter section. Please be assured that you will be sent important information about new products only.
Cancellation of our newsletter is possible at any time!
Dear retailers,
please note the following information:
You will gain access to our retail net price list as soon as your company's application as retailer has been registered successfully and accepted by us.
Please remit your personal company data at our disposal also by mail or telefax no. ++49 8095 8951.
Retailer accounts can be released during office hours, from Monday to Friday.
This information is addressed to such customers who already dispose of a customer account with us.
All retailers who do not dispose of a customer account with us, will first have to apply for one.
You will be surprised our shop 'rc-easy' is very modern and pays much attention to the matter of security. - Your e-mail address serves as log-in.
Your log-in name is unique - every transaction will be followed by a confirmation sent to your e-mail address in return. This is a very safe procedure and assures you will know about the state of your log-in at any time.
Let us invite you to have a look at our shop - we promise there is much to discover!
All visitors who want to be registered, please click here.
Please go ahead and enjoy shopping!
- New - New - New - New - New - New- New
Jeti Model released 2,4Ghz duplex technology
for more info please click on the duplex symbol.
System Duplex 2.4 GHz We present the new innovative DUPLEX system from JETI Model for radio controlled models of all types working on the 2,4GHz band. Problems with interference and frequency control will be history, and operation on the 2,4GHz band will change your approach to radio control forever. In designing the DUPLEX system, our aim has always been to improve on what is offered by other radio control systems currently on the market.
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Neuigkeit, schauen Sie sich die Detailansicht an!


text: LAHORE (AFP) - Pakistan Cricket Board (PCB) has rejected reforms which could see the country lose the right to have one of its nationals at the head of cricket's governing body, an official said Tuesday. A plan to scrap the rotation policy for appointing presidents and vice-presidents of the International Cricket Council (ICC) is likely to be tabled at its board meeting in Hong Kong later this month. "Under the current rotational system, Pakistan and Bangladesh have to put up the next candidates for president and vice-president and we don't agree with the proposal of change and we have shown our reservations to the ICC," Pakistan Cricket Board (PCB) chief operating officer Subhan Ahmed told reporters. Subhan Ahmed said Pakistan and Bangladesh had the right to nominate their candidates. "We are in touch with the ICC over the matter and will decide the future course of action soon," said Ahmed. The post of ICC president was first created in 1997 when India's Jagmohan Dalmiya took the top job. He was followed by Australian representative Malcolm Gray, followed by Ehsan Mani of Pakistan and Percy Sonn from South Africa. India's Sharad Pawar is the current president and will be succeeded by Australia-New Zealand nominee Alan Isaac next year. Pakistan and Bangladesh will nominate their candidates after Isaac completes his term in 2014. It was unclear what new system for picking ICC presidents would replace rotational appointment. Pakistan has also opposed another suggested amendment in the ICC's constitution allowing the council to suspend members in cases of government interference in the running of national cricket boards. The role of PCB chairman is widely criticised for being a political appointment by the ruling administration.


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GO Run 50
The GO Run 50 is a powered by a 2.75HP motor designed to take on competitive athletes and casual joggers alike. It can go up to 12mph and inclines up to 12%.
Product Description
The GO Run 50 is a powered by a 2.75HP motor designed to take on competitive athletes and casual joggers alike. It can go up to 12mph and inclines up to 12%. Also included are 17 training programs including a heart rate control program ensuring that you don't get bored of using the same programmes.
The Tunturi GO Run 50 is a high specification home running machine. It has a 150cm long running surface that is suitable for taller users with a longer stride length, it accommodates users up to 135Kg. The GO Run 50 has been designed to suit all users of various fitness levels but will help you to push fitness limits.
|2.75 HP (DC) (5.0 peak power)
|Speed Km/ h
|0.8 - 20.0 (± 0.1)
|0 / 12% (± 1.0)
|Running surface (LxW)
|149 x 50 cm
|Running deck type
|Power supply
|Shock absorbing system
|198 cm - 77.95 inch
|Length Folded
|78 cm - 30.71 inch
|85 cm - 33.46 inch
|Width folded
|85 cm - 33.46 inch
|132cm - 51.97 inch
|Height folded
|172 cm - 67.72 inch
|Packaging ( LxBxH Gew. )
|200x87x38 cm / 110 kg
|Maximum user weight
|135 kg / 300 lbs
Exercise Tips
Walking and running are the most natural forms of exercise, and with a treadmill you can do both in the comfort of your home. They're ideal if you have a family, since people of all ages can use them. Your fitness goals can include general fitness, weight loss, or building up stamina.
General fitness
A few half-hour sessions on a treadmill will improve your aerobic fitness - the basic conditioning that lets you walk or run without getting out of breath. Better aerobic fitness means more energy and enthusiasm for everyday life.
Weight loss
Treadmills offer an effective way to burn calories without stressing your body. You can set the 'pace' of the treadmill to a slow walk or fast run - and simulate hills to make it harder. A long, gentle jog or fast walk is an excellent method for losing weight, especially if you do it regularly.
A treadmill will make your heart stronger, meaning you'll be able to walk or run for longer distances without stopping. The ability to keep going is useful for both life and work!


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Well, I'm back to blogging.... I hope! The truth is I've been really busy with work and blogging has felt like another commitment that I just haven't had the heart for. I had a really busy wedding season this year and met a lot of amazing people, as well as made a lot of wonderful photos that I'm really excited to share over HERE.
The good news is that I have more time this week and for the next few months to get caught up on all those little things I've neglected like marketing my business, spending time relaxing on a beach instead of working, vacations, patting my kitty cats, cooking, etc. So, I'll make sure to get back to sharing it all with you here on Sage Island.
{Photo source}


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$3 Million Gift Will Bolster Student Health & Wellness at Bucknell
Read more
See winners of this year's photo contest, part of International Education Week, an annual celebration that takes place on campus and around the world.
Studying abroad can be a life-changing experience for undergraduates, as they expand their perspectives in an increasingly interconnected world. This year's winners of Bucknell's International Photo Contest, which took place during International Education Week, Nov. 14–18, submitted photos that they say reflect the impact their international experiences had on them.
The U.S. Department of State and the Department of Education started International Education Week in 2000 as a way to celebrate the benefits of international education and exchange. Now it is observed at schools and campuses in more than 100 countries. Bucknell celebrates the November tradition annually.
"Our aim is for the entire campus community to gain a deeper appreciation of our interconnected, global world," said Anita Casper, global education adviser. "We recognize the many international events that happen on campus during the entire month of November, which include student organization dinners, arts and cultural programming and events with an academic focus. This year the Office of Global & Off-campus Education coordinated 'Viewpoints on Immigration from Abroad,' a panel discussion that presented a personal side to this complicated issue as students, staff and faculty shared their stories."
The photo contest has become an important aspect of the week, said Jennifer Figueroa, director of International Student Services, whose office coordinates the contest. "The annual International Education Week Photo Contest allows us to publicly appreciate and celebrate the artistic expression, learning and cultural appreciation that can happen through travel," said Figueroa. "Our students submit photos taken outside of their home country, and they remind us to explore other cultures, learn from each other and embrace the unknown."
This year's winners were chosen from 93 entries in five categories: cityscape, animals and wildlife, nature, people, and culture and traditions. See their photos — and the stories behind them — below. Photos will be on display in Bertrand Library through January.
Winner – Cityscape
Nono Fan '20, undeclared management
Studies abroad in: United States
Photo taken in: Abu Dhabi, United Arab Emirates
"As an international student from China, I am now studying abroad. I love traveling and have been to many different countries. I think this experience lets me accept different cultures and people easily. I am always curious about different countries and cultures and want to learn more about them in my future study."
Winner – Animals and Wildlife
Payton Kirkpatrick '17, biology
Studied abroad: Spring 2016, University of Otago, Dunedin, New Zealand
Photo taken in: Wanaka, New Zealand
"My study abroad experience was very important to my education at Bucknell. By studying abroad I got to experience what a different educational setting was like, and better engage with the aspects of Bucknell's educational system when I returned to school the following fall."
Winner – Nature
Khoi Le '18, computer science
Studied abroad: Summer 2016, Kyoto, Japan
Photo taken in: Kyoto, Japan
Winner – People
Morgan Robison '17, markets, innovation & design and studio art
Studied abroad: Spring 2016, Semester at Sea
Photo taken in: Mui Ne, Vietnam
"Studying abroad is an essential component to who I have become today. As someone who loves to learn, studying abroad made the world my campus, and although there is no way to make that not sound cliche, it is the truth. I felt the widest and most intense range of emotions and found commonalities with those who have lived very different lives than my own. It exposed me to what is really important, and it impacted how I want to spend my time after college. It gave me the push out of the nest I needed to know there is still a great unknown to navigate, and it opened my heart to do so fearlessly."
Winner – Culture and Traditions
Alexa Presto '17, interdepartmental
Studied abroad: Fall 2015, Semester at Sea
Photo taken in: Sahara Desert, Morocco
"Studying abroad on Semester at Sea allowed me to acquire a perspective on the economies, challenges and conflicts affecting developed and emerging nations. I had the opportunity to learn how many of these economies look at sustainability and harness energy with their natural resources. When I returned to Bucknell, my experience brought an international perspective to my continued studies in real estate and sustainable urban development, as well as to my conversations with my professors and fellow students."
The following links are virtual breadcrumbs marking the 27 most recent pages you have visited in Bucknell.edu. If you want to remember a specific page forever click the pin in the top right corner and we will be sure not to replace it. Close this message.


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The Motley Fool Discussion Boards
|Previous Page
Financial Planning / Tax Strategies
|Subject: Re: Real estate in an IRA
|Date: 8/14/2001 12:05 AM
|Author: jailleres
|Number: 53314 of 129307
Don't forget the tax rate differences - IRA (traditional, not Roth) distributions are taxed as income. That means that on top of paying your marginal tax rate (28%?) they increase your exposure to Social Security income taxation when you retire.
OTOH, capital gains tax rates are 20% if you're in the 28% bracket and drop to 8% if you get joint income below $43850 (2002). Of course, we don't know what they'll be in 30 years either, but you have to make some projections.
I agree with the other posters - get a mortgage to buy the property. Invest the IRA in a GNMA fund.
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Coloured Glass & Sterling Silver Charm Bracelet
DescriptionShowcase your style with this coloured glass ans sterling silver charm bracelet. Featuring a pink and black murano glass charm, flanked by a sterling silver spacer and a further coloured glass charm on either side, this will set off your look. Comes on a 19cm (7.5") black leather charm bracelet with sterling silver classic barrel clasp. Available online and in Charm Boutiques only.
Product Details
- Metal content Sterling Silver
- Metal colour Silver
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- Length 19cm/7.5"
Delivery & Returns
FREE delivery for all orders over $100. Orders under $100 will be charged a flat fee of $9.90.
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For more information, visit our FAQ page.
Care & Cleaning
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Several states have recently implemented laws that could impact you and the way you drive. Perhaps the law with the widest reach is the prohibition of texting while driving. For instance, in 47 states, texting while driving is against the law for everyone, regardless of age.
Among those 47 states, however, there are six states that enforce only partial bans on texting while driving. Many residents and officials in these states are pressing for legislation that would prohibit all drivers from doing so. South Dakota banned texting while driving only for people who have only a restricted minor license. Arizona made the practice illegal only for school bus drivers. Oklahoma followed a similar route, but included novice drivers as well.
Alabama, likewise, banned cell phone use only for novice drivers. South Carolina has not passed legislation outlawing it either, but individuals and even mobile phone companies have addressed the hazard. AT&T (http://www.att.com/) launched a campaign entitled "It Can Wait," referring to text messages received while driving. Mobile phone users now have the option of having an auto-reply message sent when they receive a text while driving, or having their text messages read out loud to them.
The movement against texting and driving attracts even more attention and support when mobile service providers, themselves, encourage you to abstain from using their product. It is more important to them that you drive safe (Distraction.gov). Montana has yet to implement a statewide ban, but seven of their largest cities are currently enforcing laws against it. With the immense popularity of laws against texting while driving, one might expect that, within a few years, every state will be prohibiting it. We shall see.


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Chapter 6
A profound stillness reigned in the Casa Gould. The master of the house, walking along the corridor, opened the door of his room, and saw his wife sitting in a big armchair -- his own smoking armchair -- thoughtful, contemplating her little shoes. And she did not raise her eyes when he walked in.
`Tired?' asked Charles Gould.
`A little,' said Mrs Gould. Still without looking up, she added with feeling, `There is an awful sense of unreality about all this.'
Charles Gould, before the long table strewn with papers, on which lay a hunting crop and a pair of spurs, stood looking at his wife: `The heat and dust must have been awful this afternoon by the waterside,' he murmured, sympathetically. `The glare on the water must have been simply terrible.'
`One could close one's eyes to the glare,' said Mrs Gould. `But, my dear Charley, it is impossible for me to close my eyes to our position; to this awful . . .'
She raised her eyes and looked at her husband's face, from which all sign of sympathy or any other feeling had disappeared. `Why don't you tell me something?' she almost wailed.
`I thought you had understood me perfectly from the first,' Charles Gould said, slowly. `I thought we had said all there was to say a long time ago. There is nothing to say now. There were things to be done. We have done them; we have gone on doing them. There is no going back now. I don't suppose that, even from the first, there was really any possible way back. And what's more, we can't even afford to stand still.'
`Ah, if one only knew how far you mean to go,' said his wife, inwardly trembling, but in an almost playful tone.
`Any distance, any length, of course,' was the answer, in a matter-of-fact tone, which caused Mrs Gould to make another effort to repress a shudder.
She stood up, smiling graciously, and her little figure seemed to be diminished still more by the heavy mass of her hair and the long train of her gown.
`But always to success,' she said, persuasively.
Charles Gould, enveloping her in the steely blue glance of his attentive eyes, answered without hesitation:
`Oh, there is no alternative.'
He put an immense assurance into his tone. As to the words, this was all that his conscience would allow him to say.
Mrs Gould's smile remained a shade too long upon her lips. She murmured:
`I will leave you; I've a slight headache. The heat, the dust, were indeed--I suppose you are going back to the mine before the morning?'
`At midnight,' said Charles Gould. `We are bringing down the silver tomorrow. Then I shall take three whole days off in town with you.'
`Ah, you are going to meet the escort. I shall be on the balcony at five o'clock to see you pass. Till then, good-bye.'
|Copyright: All texts on Bibliomania are © Bibliomania.com Ltd, and may not be reproduced in any form without our written permission. See our FAQ for more details.


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Congrats to @WhiteHouse reporter @AprilDRyan on her new Book in stores now! pic.twitter.com/ffzc3IYQqU #nabj #mediadiversity
— NABJ Headquarters (@NABJ) February 9, 2015
Book Journey
So excited about the @BUHTC conversation…
So excited about the @BUHTC conversation with @AprilDRyan hosted by @comugrad alumna @KarenHolmesWard from #wcvb pic.twitter.com/njupXGv4Nd
— Taylor Walker (@TaylorReports) February 3, 2015
The Conversation Begins
And the conversation begins with these two incredible women in the media! @KarenHolmesWard @AprilDRyan @BUHTC pic.twitter.com/9srvBUvxky
— Noelia Valero (@Noelia_Valero) February 3, 2015
Morgan State Display
Wow! The book store display at my Alma Mater, Morgan State University!! Whew! pic.twitter.com/H3btlUEJqk
— AprilDRyan (@AprilDRyan) January 30, 2015
From the Book Tour 1/27/15
January 28, 2015
Good times. Congrats @AprilDRyan @awkwardblkgrl pic.twitter.com/yDEHVt429Y
— Jonelle Henry (@JonelleHenry) January 27, 2015


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We are innofy – intellectual property for innovators, by innovators. Our clients and partners trust us to protect their innovations. We respect this trust by always acting with integrity, and by constantly striving to be the very best at what we do. Excellence is not a destination, it is a journey of continuous improvement – are you ready to join us on the road?
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How we work
Most patent and trade mark attorneys won't tell you this, but our relationship with clients is a classic example of information asymmetry. This asymmetry means that it is very difficult for clients to evaluate the quality of an attorney before, during, and even after work has been completed. The asymmetry is amplified by the fact that patents and trade marks are often not tested for years after they were originally lodged. This is a business risk that innovators need to understand, and mitigate. At innofy our role is to educate as much as it is to execute instructions from clients. We genuinely want you to succeed, and by empowering you to make informed IP decisions, and to evaluate the quality of our advice and deliverables – we all end up in a better spot.
Our refreshingly honest approach is backed by innovative systems, modern business processes, and evidence based management practices. However, that is not the end of the story – we believe in continuous improvement – relentlessly evaluating and tweaking our practice in order to evolve in lockstep with our clients changing needs. Our values are not an organisational afterthought, relegated to a dusty corner of our website. Rather, our values and ethos drive our business, because we understand that to be successful we need to innovate. In short, we are a disruptive modern IP consultancy – designed from the ground up to engage with innovators in a language they understand, and to deliver a value proposition that the market sorely needs.
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Dr Katherine Rock
Engineer | Attorney | Innovator
Dr Andrew Clarke
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Leah has experience at top-tier firms in Australia and New Zealand, specialising in complex patent and trade mark portfolio management.View Profile
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- Due to Andrew's exceptional skills in facilitating the ongoing protection of the Intellectual Property vested in my company, Clockwork Coffee, I was able to seek significant investment leading to the expansion and diversification of my business.Scott Parker, OwnerClockwork Coffee
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call: 1300 805 855 (Australia); +61 402 436 601 (International)
mail: P.O. Box 800, Fortitude Valley Q 4006


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St. Gobnait's Nursing Home
St. Gobnait's Nursing Home
Co. Limerick
Contact: Teresa Kelleher
Tel No: 00353 (0) 63 82065
HIQA Reports http://www.hiqa.ie/social-care/find-a-centre/nursing-homes/st-gobnaits-nursing-home
St. Gobnaits is a country nursing home with a warm friendly atmosphere the minute you step inside the front door.
It is located in Ballyagran Co. Limerick, approx five miles from Charleville town.
It was established in 1985 when Dermot and Teresa Kelleher saw the need for a nursing home in the area.
Teresa was working as a P.H.N. at the time.
Dermot and Teresa purchased a private dwelling house adjacent to their own home and developed and extended it over the years.
St. Gobnait is patron saint of Ballyvourney, Co. Cork, Dermot's home place, so this is where the name originated.
It is now home to twenty residents and celebrated it's silver jubilee with a big party in December 2010.
Teresa is the matron and proprietor and her daughter, Maura, also a nurse, joined the management team in December 2010
View Larger Map Residential Care Inspections
A copy of each Hiqa report can be obtained online at:
St. Gobnait's Nursing Home | www.irishnursinghomes.eu
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For further information on Irish Nursing Homes in Ireland feel free to check out the Health Information and Quality Authority (HIQA) website.The address is http://www.hiqa.ie
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- Mental Health Ireland
- United Against Prostate Cancer


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Published in Al Ahram Weekly on 24/9/2017
President Abdel-Fattah Al-Sisi's call for a revived peace process between the Israelis and Palestinians signals that Egypt will spare no effort in furthering peace in the region, writes Hany Ghoraba
For over four decades, Egypt has been blazing the trail for a peace process between the Arabs and Israelis that could finally put an end to a struggle that has been going on since the early 20th century.
Since the time of former president Anwar Al-Sadat the Egyptian leadership has believed that the ongoing struggle would never attain any further results apart from deepening animosities and furthering destruction and wasting more human lives. Egypt has believed that a peaceful resolution could only be attained based on UN Security Council resolutions 242 and 337. These would be the basis of an internationally agreed two-state solution that secured recognition of a Palestinian state and Israel living side-by-side.
However, the efforts of Egyptian diplomacy have been stifled by regional and international complexities over the past four decades. In spite of Egypt's role in mediating peace talks, international peace conventions and one-on-one negotiations between the Palestinians and Israelis, such efforts have been blocked by the vicious cycle of violence between the Palestinians and Israelis as well as the insistence of both sides on their own versions of mostly unattainable and unrealistic peace terms.
During his recent speech at the UN, President Abdel-Fattah Al-Sisi addressed the citizens of Israel, stressing Egypt's role as a guarantor of any future peace deal between the Israelis and Palestinians and urging them to press their leaders to move forward in the negotiations. It is not the first time that the president has called upon the Israelis to commit to reviving a frozen peace process. However, this was the first time that Al-Sisi had made this call from an international podium, signifying that Egypt will spare no effort in furthering the long-coveted peace between the Palestinians and Israelis.
Egyptian diplomacy has been scrambling for months to reconcile the warring Palestinian factions of Hamas and Fatah in an attempt to mend a relationship that was severed after the Hamas coup in Gaza in 2007 that ousted the Palestinian Authority government from the Strip and put it under Hamas control. For years, Hamas has acted as a rogue organisation and has committed acts of terrorism and violence. However, the confrontation with Egypt and its ongoing support for terrorists in Sinai and support for the Muslim Brotherhood have proven to be very costly for Hamas.
Egyptian diplomacy has looked beyond the fact that Hamas is an offshoot of the banned Muslim Brotherhood group, and it has also overlooked the crimes that Hamas has committed against Egyptians over the past decade, especially in arming terrorists and smuggling weapons into Sinai. The Hamas stance now appears to be the group's last hope of remaining in power after losing the financial support it was receiving from Qatar, along with the political support it had garnered from countries such as Syria over the years.
On the other hand, the Israelis, especially under the current government of Israeli Prime Minister Benjamin Netanyahu, have been stifling the peace negotiations with unrealistic demands, citing security fears and the supposed inability of the Palestinians to reunite under one banner to conduct meaningful negotiations. Egypt may be able to remove these excuses by bringing Hamas and Fatah together at the negotiating table, with Hamas accepting Fatah's terms for reconciliation for the first time in 10 years.
After eight decades of conflict, the Palestinian and Israeli sides may have reached the conclusion that most of the world has already reached — that no military solution will resolve the Palestinian-Israeli conflict. Neither side will be able to reach a decisive victory in an area that is among the most densely populated on the planet. Moreover, neither side will receive any form of applause for its military actions, with the exception of the traditional White House support for Israeli incursions into the Occupied Territories that are usually followed by the statement that "Israel has the right to defend itself."
But that sort of support from the United States has not garnered Israel many benefits, and the European Union, its traditional supporter, shifted its stance over a decade ago, with countries such as Sweden, France and Belgium taking firmer diplomatic actions against Israel. It is therefore in Israel's interest, just as it is in that of the Palestinians, to sit at the negotiating table to reach a final settlement to a century-old struggle initiated after the UK's Balfour Declaration in 1917.
Both sides must believe that a less than satisfying settlement is far better than prolonging a painful struggle for another generation. The face of the Middle East will not be the same once this hotbed of trouble ceases to exist and peace reigns once and for all. A settlement would also strip the jihadists of their excuse to wage war under the pretence of liberating Palestine. For over eight decades they have been using the struggle as an excuse for waging terrorist attacks against innocent people. Removing this excuse would stop them from using it to recruit young men and women to their cause.
According to the 16th-century Dutch philosopher Erasmus, "the most disadvantageous peace is better than the most just war." Today, his words too often still fall on deaf ears in the Middle East. Unfortunately, not everyone in the region realises the benefits of having peace in the region, and there are regimes, terrorist groups, political parties, journalists and politicians who have made their careers out of the Arab-Israeli conflict and are not likely to welcome tangible steps towards a final resolution to the age-old conflict.
However, perhaps more than at any other time in recent history, there is a conviction that today there is a golden opportunity to establish peace in the Middle East after the region has been torn apart by the conflicts in the aftermath of the Arab Spring. It is in this context that Al-Sisi's call for peace made during his UN General Assembly speech this month should be seen as a new chance for peace in a troubled region.
Original Post in Al Ahram Weekly


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A limited edition festive fragrance has been added to our luxury Naturally European Room Diffuser range. Simply place the reeds into the fragrance and let the evocative aroma of Cranberry and Orange delicately infuse the room.
Instructions for use:
1. Unscrew the black collar, remove the plastic stopper and then reattach the black screw top collar.
2. Place the reeds provided into the bottle and leave for a few minutes to allow the perfume to be absorbed.
3. Remove the reeds from the bottle and place the dry ends back into the oil to absorb more of the fragrance.
If you wish to increase the intensity of the aroma, repeat step 3 until you reach the desired effect. The rate of evaporation is dependent on air conditions and the frequency with which the reeds are turned.
Explore our Naturally European Room Diffusers for more scintillating fragrances Freesia & Pear, Neroli & Tangerine, Milk Cotton, Ginger & Lime, Rose Petal, Verbena and Lavender.
100 ml / 3.38 fl oz
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Election day 2014 is a big day for Williams College. In Massachusetts, Martha Coakley '71 is running for governor. In Virginia, a pair of Ephs are battling each other for a spot in the US House of Representatives. And in San Francisco, twenty-nine-year-old Stevon Cook is making his first bid for elected office as a candidate for the city's School Board.
In many ways Cook's story is the most remarkable. Born and raised in public housing in San Francisco's Bay View region, Cook struggled to find his way in a world set against him. He was educated in failing public schools, saw drugs and alcohol break apart families of friends and loved ones, and watched as many of his childhood peers lost hope for a better future.
Arriving at Williams in the fall of 2004, Cook took pride in the fact that he had defied the odds. Thousands of miles from his home, Cook saw Williams as the launching point for a life of impact. He harbored visions of himself as the first black governor of California.
But Williams was difficult. Cook had always prided himself as being a top student, but he quickly found himself struggling to stay in the middle of the pack. It wasn't until junior year that he joined his first extracurricular group – a public service organization called the Griffin Society. "The people who would be most surprised that I'm running for public office would be the people I went to college with because I was not, not, not that type of person at Williams."


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Walking back to the Metro-North train from the Harlem Book Fair last month, I couldn't help but glance with longing over at the corner of Lenox Avenue and 131st Street where Liberation Bookstore had held court for nearly 40 years.
Liberation Bookstore was founded in 1967 and run by Una Mulzac, a woman whose knowledge of Black heritage, and memorable personal style, were both seasoned cultural treasures in themselves.
When you walked into Liberation, you were as much impressed with how small the shop was as you were with how much material was packed into it. Books and pamphlets and posters filled up much of the wall and floor space—the shop was a veritable repository marking the pr
ogression of Black American politics, economics, health issues, social movements and cultural arts.
Una Mulzac is 85 years young, now, frail but still feisty, as relayed to me in an email from her niece Leticia Mulzac.
And now, the thousands of items that remained after Liberation Bookstore closed is being offered for sale, explained in an email that Leticia Mulzac sent (reprinted below)
Leticia Mulzac says that the inventory will only be available for a short time given consideration of the cost of maintaining the thousands of items in its catalog. In an email to me last week, she said "a decision must be made soon."
Please read the email below and send around to any institution or person whom you think could keep this archive together and available to the public. Thanks.
And my warmest thanks to you, Ms. Una Mulzac, for keeping the banner raised so admirably for so long.
Email from Leticia Mulzac (reprinted with permission):
From: Leticia Mulzac <firstname.lastname@example.com
Date: Sun, Jul 18, 2010
Subject: Liberation Bookstore (see attached PDF for Inventory)
I am writing to you in regards to my Aunt Una Mulzac, owner of the historic Liberation Bookstore in Harlem for over 35 years.)
For most of her life she dedicated herself to improving the condition of the African American people through education and as an activist championing civil rights causes. Her work has been recognized and praised by many in the community and has been interviewed on many occasions. It was her father's legacy, Hugh Mulzac, himself an important historical figure that inspired her to work endlessly to advance the cause that became her life's work.
At 85 years old she was no longer able to look after herself or her business. I am now working with her legal guardian to find a buyer for her stock of books - a catalog of nearly 10,000 political & historical titles - some that have been out of print for many years. The collection is perfect for a cultural or educational institution. This collection is on offer as a whole and open to any party with a vested interest in maintaining their educational value. While many libraries are working with limited budgets, perhaps a philanthropic alumni association would be able to purchase the collection on behalf of their alma mater.
Anything interest or helpful suggestions would be most appreciated. Please respond as soon as possible since time is of the essence. I would be happy to forward the inventory list to you.
Leticia Mulzac
[Minor edits were made to this post on Monday, February 28, 2011.]


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Is Medical Science Winning the War on Cancer?
The American Cancer Society (ACS), the Centers for Disease Control and Prevention (CDC), the National Cancer Institute (NCI), and the North American Association of Central Cancer Registries (NAACCR) collaborate to provide annual updates on cancer occurrence and trends in the United States. On May 22nd, they released their latest Annual Report to the Nation on the Status of Cancer, part I: National cancer statistics.1
Not surprisingly, they patted themselves on the back. As NCI Director Ned Sharpless, M.D said, "This year's report is an encouraging indicator of progress we're making in cancer research. As overall death rates continue to decline for all major racial and ethnic groups in the United States, it's clear that interventions are having an impact. The report also highlights areas where more work is needed. With steadfast commitment to patients and their families, we will be able to lower the mortality rates faster and improve the lives of those affected by cancer."
So, as always, the question of the day remains: is such self-congratulations warranted? And the answer is: yes, some progress has been made, but not as much as is claimed. But on a happier note, medical gains against cancer are likely to be faster and more pronounced moving forward.
Summary of the Annual Report
Note: the report explored data for both cancer incidence and mortality. The incidence data for the report was obtained from the CDC‐ and NCI‐funded population‐based cancer registry. Data on deaths from cancer was obtained from the National Center for Health Statistics National Vital Statistics System. According to the report:
- Overall cancer mortality rates decreased by 1.8% per year among men and by 1.4% per year among women from 1999 to 2015.
- Among men, death rates (2011‐2015) decreased for 11 of the 18 most common types.
- Among women, death rates declined for 14 of the 20 most common cancers.
- Among children, overall cancer death rates decreased by 1.5% per year from 2011 to 2015.
- Death rates decreased for cancer sites, including lung and bronchus (men and women), colorectal (men and women), female breast, and prostate.
- Death rates increased for cancers of the liver (men and women); pancreas (men and women); brain and other nervous system (men and women); oral cavity and pharynx (men only); soft tissue, including heart (men only); nonmelanoma skin (men only); and uterus.
- Incidence and death rates were higher among men than among women for all racial and ethnic groups.
- For all cancer sites combined, black men and white women had the highest incidence rates compared with other racial groups, and black men and black women had the highest death rates compared with other racial groups.
- Non‐Hispanic men and women had higher incidence and mortality rates than those of Hispanic ethnicity.
- Five‐year survival for cases diagnosed from 2007 through 2013 ranged from 100% (stage I) to 26.5% (stage IV) for female breast cancer, from 88.1% (stage I) to 12.6% (stage IV) for colorectal cancer, from 55.1% (stage I) to 4.2% (stage IV) for lung and bronchus cancer, and from 99.5% (stage I) to 16% (stage IV) for melanoma of the skin.
In summary, for all types of cancer combined, cancer incidence rates decreased among men but were stable among women, with both incidence and death rates higher in men than in women in every racial and ethnic group. Also, there continue to be significant declines in cancer death rates among both men and women. That said, progress in reducing cancer mortality has not occurred for all types of cancer. Increases in death rates for several cancers continue to cause concern. Researchers suggest that the increase in liver cancer death rates is related to the high prevalence of hepatitis C virus infection among Baby Boomers, as well as to the high prevalence of obesity in the United States. Obesity is also thought to have contributed to the increase in death rates from cancers of the uterus and pancreas. The recent increase in oral cavity and pharynx cancer death rates among white men is thought to be associated with human papillomavirus infection.
According to the Director of the National Cancer Institute, Ned Sharpless, M.D., "This year's report is an encouraging indicator of progress we're making in cancer research. As overall death rates continue to decline for all major racial and ethnic groups in the United States, it's clear that interventions are having an impact."
Finally, the report also describes five-year survival during 2007-2013 by cancer stage at diagnosis for four of the most common cancers--female breast cancer, colorectal cancer, lung and bronchus cancer, and melanoma of the skin. While five-year survival is high for early-stage disease for breast cancer, colorectal cancer, and melanoma, survival remains low for all stages of lung cancer, ranging from 55 percent for Stage I to 4 percent for Stage IV.
"This report underscores that if cancer is caught early, when it has the best chance of being treated, patients can live longer," said CDC Director Robert R. Redfield, M.D. "Early detection and timely, quality treatment are keys to saving lives."
Prostate Cancer
In a companion study, researchers explored prostate cancer trends in more detail.2 They found that overall prostate cancer incidence rates declined an average of 6.5 percent each year between 2007 and 2014. However, the incidence of "distant disease"--that is, of cancer that has spread from the original tumor to other parts of the body--increased from a low rate of 7.8 new cases per 100,000 in 2010 to 9.2 new cases per 100,000 in 2014. Furthermore, after two decades of decline between 1993 and 2013, prostate cancer mortality leveled off between 2013 and 2015.
This study also reports a decline in prostate-specific antigen (PSA) screening based on a series of national surveys. The reported decline in screening occurred between the 2010 and 2013 surveys for men between 50 and 74 years of age, and after the 2008 survey for men age 75 and older.
According to Serban Negoita, lead author of the study, "The increase in late-stage disease and the flattening of the mortality trend occurred contemporaneously with the observed decrease in PSA screening in the population. Although suggestive, this observation does not demonstrate that one caused the other, as there are many factors that contribute to incidence and mortality, such as improvements in staging and treating cancer. Additional research is needed to get a more comprehensive understanding of the recent trends and the possible relationship with PSA screening, as well as the relationship with other factors that may be associated with these trends."
Yes, but
The report is enthusiastic about two things: the incidence of cancer is down and mortality is down--particularly the five year survival rate. Again, to quote Robert Redfield, "This report underscores that if cancer is caught early, when it has the best chance of being treated, patients can live longer." So, let's take a look at those two claims.
The Incidence of Cancer is Down
So, what's my problem with this claim? Quite simply: incidence may be down, but what does medical care have to do with it? It's not like doctors are giving people a cancer vaccine that prevents cancer. No, medical care has little to do with it. On the other hand, doctors are no longer doing things that promote a higher incidence of cancer. I'm talking about:
- The reduction in cigarette smoking. This is the major reason that both lung cancer incidence and mortality rates have declined. And let's not forget that not only does smoking increase the risk for lung cancer, it's also a risk factor for cancers of the: Mouth, Larynx (voice box), Pharynx (throat), Esophagus (swallowing tube), Kidney, Cervix, Liver, Bladder, Pancreas, Stomach, Colon/rectum, and Myeloid leukemia3--oh, and prostate cancer.4 A recent meta-analysis showed that smokers are 24% more likely than nonsmokers to die from prostate cancer. So, we're talking about reducing a whole lot of cancer incidence and mortality simply from the reduction in smoking in the US. But can doctors claim credit for the reduction--especially when they played a major role in promoting cigarette smoking in the first place?5
- In case you're too young to remember, the Journal of the American Medical Association ran ads for cigarettes from 1933-1953 and published position papers promoting the virtues of cigarette smoking. Yes, they really did that.6
- Then there's breast cancer, the second leading cancer for women after lung cancer. It has become clear that long-term use (several years or more) of hormone replacement therapy after menopause increases the risk of both breast cancer7 and ovarian cancer,8 as well as the risk of heart disease, blood clots, and strokes. (Note: five years after stopping HRT, the breast cancer risk appears to drop back to normal.) Additionally, studies have found that women now using birth control pills have a greater risk of breast cancer than women who have never used them.9 (After 10 years of non-use, the risk goes away.) Some experts believe U.S. breast cancer rates dropped sharply in 2003 because many women suddenly stopped menopausal hormone10 use after disturbing results from the Women's Health Initiative study were released. So once again, we have to ask the question: do doctors get to claim credit for a reduction in breast cancer rates simply by reducing the number of prescriptions they were writing for the HRT--those same prescriptions that were causing much of the cancer in the first place?
- And we see the same thing with prostate cancer. Looking at the incidence rates, we see rates rise dramatically in the late '80s when PSA testing came into wide use. But since the early '90s, incidence has been steadily declining. What could have been responsible? Well, when we look at the trend in tobacco use chart that we saw earlier, we can see that the decline in incidence perfectly aligns with the years men started to quit smoking in large numbers. So once again, it's hard to credit the medical community for the decline in the incidence of prostate cancer.
The bottom line is that if the medical community wants to take credit for the downward trend in cancer incidence, considering they had nothing to do with it, then we should expect them to take the blame for the surge in suicide rates to the highest levels in 30 years11--even though they have no direct connection with that situation. Fair is fair.
People Are Living Longer with Cancer
And then the medical community claims that people are living longer--largely thanks to early detection and improved treatments.
Well, if you want to be snarky about it:
- Even if the treatment makes no difference and you die at exactly the same time as you would have without the treatment
- But you detected the cancer 1-2 years earlier
- Then statistically, it will look like you lived 1-2 years longer--even though you didn't
And yes, there's some truth to our little syllogism. But to be fair, there have been some major advances in cancer treatment that have indeed extended life beyond the extra innings that result from earlier detection.
Thanks to changes in medical thinking (no more radical mastectomies) plus the advent of laparoscopic and micro surgery, cancer surgery is much less brutal and disfiguring than it was in years past. And yes, if the cancer has not metastasized and you remove all the offending tumor, then yes, the cancer is gone. But if you don't remove the trigger (e.g. radon gas in your house, carcinogens in your diet, menopausal HRT, etc.), then you haven't really resolved the issue so the cancer is likely to return anyway.
As with surgery, the advent of computerized targeting has allowed radiation therapy to be much more precise--that is, to do a much better job at destroying all the cancer (assuming it hasn't metastasized), while at the same time minimizing damage to nearby healthy tissue. But radiation is still radiation, and it still has long-term impact on the body. And as with surgery, since it doesn't address the underlying trigger, there's the likelihood of the cancer returning anyway.
On the positive side, doctors have learned to be much more targeted with chemo--to identify which drugs work best with which cancers and to precisely optimize dosage to minimize harm to healthy cells. But you still have a problem. As I've explained in other newsletters, even treatments that are 99.9% effective in getting rid of the cancer cells in your body are still likely to fail. They simply leave too many viable cancer cells behind--potentially millions of surviving cancer cells, actually. To consider yourself cured, or at least in long-term remission, you actually have to destroy 99.9999999999% of all the cancer cells in your body. And that means that no matter how precise you are when it comes to dosing, you have to use a level of chemotherapy that is likely to be harmful to healthy tissue--or even fatal when it comes to the more serious cancers--if you're looking for a successful outcome. That said, there are advances in chemotherapy that are being tested now that allow for those higher doses while at the same time protecting the body from any harm…or even any side effects, for that matter.
Virotherapy can, for some cancers and some patients, be an effective cancer treatment. It involves injecting the patient with a special virus capable of finding and destroying malignant tumor cells. Viruses, as we know, can travel in the bloodstream and reach every area of the body, thus reaching every malignant cell wherever it might be hiding. Theoretically, virotherapy destroys tumor cells selectively without affecting the healthy cells of the body. It also stimulates the body's natural defense mechanisms by activating the immune system, which is often suppressed by other treatment methods. And finally, it can be used against tumors that don't respond well to radiation or chemotherapy, such as melanomas.
The greatest challenge in virotherapy, however, is making sure that viruses reach all tumor tissue at sufficient levels to pass from blood vessels into the tumor, replicate in tumor cells to create infectious centers, which then expand outwards and merge to destroy the tumor or perform effective tumor debulking. This requires constantly increasing the dose of the virus used for injection until it's sufficient to cross what is known as "the threshold dose."
But virotherapy is an emerging field, and the medical community needs to work through some major obstacles before it can become a mainstream treatment:
- A virus is a virus, which means your body will treat it as an invader, not just by attacking it with immune cells, but also by sequestering the virus in the liver and spleen. That's not useful if your cancer is located someplace else.
- As we just mentioned, your immune system will try to neutralize the virus using serum immune factors.
- The virus needs to be "modified" to "selectively" bind to tumor tissue.
- Along with the introduction of the virus, you need to selectively increase the permeability of tumor blood vessels to allow the virus to enter the tumor in massive numbers while avoiding systemic inflammation in the rest of the body.
It's early days.
Cancer Immunotherapy (Immuno-Oncology)
This is virtually the same deal as virotherapy, but instead of using a virus, it uses your own immune system to attack the cancer. Theoretically, this should be a more "natural" approach since your immune system is already designed to seek out and destroy cancerous cells. And unlike with virotherapy, you don't have to worry about immune cells attacking themselves or being sequestered in the liver and spleen. On the other hand, it may require some extra training for those immune cells to identify the cancer cells that have learned how to hide from your immune system.
The promise of Immuno-Oncology (IO) is based on the knowledge that the immune system is constantly searching for, assessing, and eliminating foreign particles from the body.12, 13 Yet, sometimes rogue cells slip past this immune surveillance and become cancers.14 By providing the immune system with tools to both unmask tumors and strengthen your body's ability to attack harmful cells, IO therapies enable the immune system to recognize and respond.15, 16
The primary problem with Immunotherapy is that it doesn't work for patients with weak immune systems, which, when you're dealing with cancer patients, leaves out 70-80% of all patients. The next step for immuno-oncology therapies, then, is to make them effective in those patients by figuring out how to activate T-CD8 cells (killer T cells) that kill tumor cells in those patients whose immune systems are normally too weak to respond.
Gene Editing
Okay, we talked about this in our last newsletter, and several people wrote in to tell us they didn't like it. But the truth is that although approaches including diet and supplements can protect your DNA from damage and can even alter the ability of damaged genes from expressing themselves and manifesting illness, there is little evidence that any tools in the alternative arsenal can "repair" damaged or faulty DNA. Gene editing theoretically can do that.
Look, the technology isn't there yet, and there are ethical issues associated with gene manipulation, but the potential is undeniable. Theoretically, one day in the future your doctor will be able to get rid of any cancer you have simply by "editing" the cancer cells in your body out of existence. You don't need to surgically remove them, burn them, poison them, send a virus after them, or even call up your immune system. It's more like one day you have cancer cells, and the next day, those same cells are now normal. Cancer gone.
Again, the technology isn't there yet, but it's advancing rapidly, and whether we like the idea or not, within most of our lifetimes, this approach will at least start to become a reality.
So, what is the answer to the question of whether or not the medical community's self-congratulations in terms of cancer is warranted?
- When it comes to reducing the incidence of cancer, the medical community has very little to do with it
- But when it comes to extending life for those with cancer, yes, the medical community has made strides and deserves credit for it--just not quite as much as they claim
On a happier note, medical gains against cancer are likely to be faster and more pronounced moving forward. Look, for years, medical treatments for cancer were almost as harmful as the gains they provided. Pursuing alternative choices was definitely a favorable option. But we may be approaching a tipping point where alternative protocols will still be your best bet for avoiding cancer--but medical treatments may be your best option for getting rid of it if you have it.
With that in mind, there are things you should be doing now to optimize your baseline of health so that you either significantly reduce your chances of getting cancer in the first place (preventing cancer is much easier than getting rid of it), or possibly reversing the cancer on your own by charging up your body to do what it was designed to do. Or, at the very least, put yourself in a much better position to have a positive response to any medical treatment you receive (such as having a strong enough immune system to benefit from cancer immunotherapy)--or in some cases, as things currently stand, just survive the treatment. Think of it as natural health insurance.
- 1. Kathleen A. Cronin, Andrew J. Lake, Susan Scott, et al. "Annual Report to the Nation on the Status of Cancer, part I: National cancer statistics." Cancer. 22 May 2018. https://onlinelibrary.wiley.com/doi/full/10.1002/cncr.31551
- 2. Negoita S, Feuer EJ, Mariotto A1, Cronin KA, et al. "Annual Report to the Nation on the Status of Cancer, part II: Recent changes in prostate cancer trends and disease characteristics." Cancer. 2018 May 22. https://onlinelibrary.wiley.com/doi/full/10.1002/cncr.31549
- 3. "Health Risks of Smoking Tobacco." ACS. (Accessed 12 Jun 2018.) https://www.cancer.org/cancer/cancer-causes/tobacco-and-cancer/health-risks-of-smoking-tobacco.html
- 4. Freedland SJ. Smoking and Death From Prostate Cancer. JAMA Oncol. Published online May 24, 2018. https://jamanetwork.com/journals/jamaoncology/article-abstract/2682184
- 5. Devra Davis. The Secret History of the War on Cancer. NY, New York: Basic Books, 2007.
- 6. "THE ADVERTISING OF CIGARETTES." JAMA. 1948;138(9):652-653. https://jamanetwork.com/journals/jama/article-abstract/302011
- 7. Chlebowski, Rowan T., Kuller, Lewis H., Prentice, Ross L., et al. "Breast Cancer after Use of Estrogen plus Progestin in Postmenopausal Women." N Engl J Med Volume 360, Number 6, pages 573-587, February 5, 2009. https://www.nejm.org/doi/full/10.1056/NEJMoa0807684
- 8. Karpasea-Jones, Joanna. "Hormone Replacement Therapy May Cause 5 Percent of Ovarian Cancer." Empowher. 10 October 2012. (Accessed 14 June 2018.) http://www.empowher.com/cancer/content/hormone-replacement-therapy-may-cause-5-percent-ovarian-cancer
- 9. "Oral Contraceptives and Cancer Risk." NCI. Reviewed 22 Feb 2018. (Accessed 14 Jun 2018.) https://www.cancer.gov/about-cancer/causes-prevention/risk/hormones/oral-contraceptives-fact-sheet
- 10. "Number of prescriptions for hormone replacement therapy (HRT) drugs among adult U.S. women from 2001 to 2008 (in millions)" statista. (Accessed 14 Jun 2018.) https://www.statista.com/statistics/305412/prescriptions-for-hormone-replacement-therapy-drugs-us-women/
- 11. Sally C. Curtin, Margaret Warner, and Holly Hedegaard. "Increase in Suicide in the United States, 1999--2014." CDC. NCHS Data Brief No. 241, April 2016. https://www.cdc.gov/nchs/products/databriefs/db241.htm
- 12. Melero I et al. "Clinical development of immunostimulatory monoclonal antibodies and opportunities for combination." Clin Cancer Res 2013; 19: 997-100. http://clincancerres.aacrjournals.org/content/clincanres/19/5/997.full.pdf
- 13. Finn O. "Immuno-oncology: understanding the function and dysfunction of the immune system in cancer." Annals of Oncology 23 (Supplement 8): viii6-viii9, 2012. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4085883/
- 14. Finn
- 15. Melero
- 16. Eggermont A and Finn O. "Advances in immuno-oncology." Annals of Oncology, Volume 23, Issue suppl_8, 1 September 2012: viii5. https://academic.oup.com/annonc/article/23/suppl_8/viii5/185159


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That was what initially turned me off while watching the previews.
I think he did a fantastic job.
A pleasant surprise.
RedLeader wrote:All i wanna know is.. was that actor able to pull off Han?
Crocaneers wrote:RedLeader wrote:All i wanna know is.. was that actor able to pull off Han?
It took a little bit, I'll admit that. You can't look at the physical. All I'll say without given everything away. You all of a sudden start thinking it's really Han Solo (at least IMO)
Buc2 wrote:Miller4Prez64 wrote:
No, he didn't. My reason being is, his whole shtick in the original trilogy was he was the selfish ***hole who learned to do the right thing. So this origin movie is just focused on a young selfish ***hole long before he grows into the character people loved? No thanks, there are a lot more Star Wars characters I would've loved to see expanded on long before Han Solo.
I think the focus will be on how he came to be who he was when we first found him in Episode IV. Where/how did he get his piloting skills? How did he meet and become friends with Chewbacca and Lando. What formed him into the man that was willing to give up profit for the right cause when the time came? Sci-fi. Better yet, space sci-fi. Yes, thanks. On top of all that, Han just died a couple episodes ago. People loved his character. As such, of course the showrunners are going to want to do a Han Solo feature. If it were my franchise, I damn sure would. While they have to please the fans, they also want to make money. Han Solo will make them money.
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sei la mia vitA*indirizzo msn° firstname.lastname@example.com due migliori vacche°°e poi scusa chi l'ha detto che il rosa sta male con il rosso? °rimani incantato dall'aspetto furioso°my heart's purple and it belongs to you.°°sei la mia vita°° ti mao angelo dagli occhi blu.Just a perfect day,Drink Sangria in the park,And then later, when it gets dark, We go home.Just a perfect day,Feed animals in the zooThen later, a movie, too,And then home.Oh it's such a perfect day, I'm glad I spent it with you.Oh such a perfect day,You just keep me hanging on,You just keep me hanging on.Just a perfect day,Problems all left alone,Weekenders on our own.It's such fun.Just a perfect day,You made me forget myself.I thought I was someone else,Someone good.Oh it's such a perfect day, I'm glad I spent it with you.Oh such a perfect day,You just keep me hanging on,You just keep me hanging on.You're going to reap just what you sow.Letme holla' at the d.j. Come on d.j. put that record on the replay Don't you see how them bitches move they bootay Everytime you play this record, smell like coochie Follow dem',Screamin' like a groupay Misdemeanor move my nookie like a hoochay For them hatas fuck whatever you say Because you know I'm too cool for you anyway I'm just a bad bitch M-I-S,Miss I'm gonna' keep talkin' shit till you get this I'm gonna' bust up in the club wit' no guest list Them otha' artist, I keep em' all restless I don't french kiss unless it's 50 cent Vivica,we can share him like the president Tabloids,I don't care,it's irrelevant,I'm heaven sent Now watch how I do this shit I'm really,really hot Everytime my records drop Radio says I won't stop Cus' I'm killin' em' You don't know whatcha' talkin' bout You would think I was Sug when I come out My album hit hard when I roll out Yall records make a bitch wanna' throw em out And that's no doubt See I rock bells Fly as hell and cool as ? Baby can't ya' tell I lick my lips like I'm L.L. And I'm doin' it,and doin' it,and doin' it well Straight to the hotel I'm cellabut so,boy,you gets no tell Kiss,kiss and still you gets nowhere Just two blue balls down in yo' underwear I play unfair I'm a hot gal Hot cars and stars and strip bars And ain't hot if I'm not there I'm a true playa' You can find me up in any record store Hurry up and get chere Look,let me move to the left Go head,let me fell myself Touch my chest my sweat Show that d.j. how I shake my breast Jiggle,jiggle,jangle Watch how my gludius dangle I do a 1-2 step,STOP No,I ain't done yet Everybody in the club,go to work Tight jeans,crop shirts,short skirts I'm gonna' rock to the beat till' it hurt I'm gonna' drop it on the streest Yeah ya' heard Hatas' I flip the bird Got guns,so what,I ain't scurred I came to boogie and swerve I ain't lyin' folk that's my word
bao io ti maovagadondando alla ricerca della luna ho incontrato la mia stella
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Glencoe White Kitchens
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Glencoe White Painted Kitchens
Glencoe, Illinois is in Cook County with almost 9,000 residents. DDK Kitchen Design Group's showroom in Wilmette is the closest of the two showrooms at less than six miles south of Glencoe. When Glencoe customers come to the DDK showroom, they are able to check-out the white kitchen design and white kitchen cabinets to determine which styles will suit their home best. What's more, DDK is proud to be a company that supports eco-friendly kitchen products and materials in order to help reduce our carbon footprint on the planet. Moreover, our Glencoe white kitchen designers will coordinate the delivery of its Glencoe clients' white kitchen cabinets with the labor schedule. That way we can ensure that their white kitchen cabinets will be onsite prior to the arrival of the DDK installer. It comes as no surprise that our Glencoe clients realize that not only can they anticipate that DDK will meet their expectations, but they will most likely surpass them!
Glencoe White Kitchen Cabinets
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The South Korean government has approved a request to launch student exchanges between the top universities of the two Koreas.
A representative of a students' group at Seoul National University said on Tuesday that the Unification Ministry endorsed the group's plan to meet with North Koreans, adding it will send a fax to Kim Il-sung University in Pyongyang as early as next week to make an official proposal for a student exchange program between the two colleges.
The SNU students' group submitted the request and the outline of the exchange program to the ministry on May 24th.
It will be the first time since its founding 72 years ago that SNU will begin a student exchange program with a North Korean university.
It's expected the SNU students' group will propose the visits to Kim Il-sung University by SNU students and joint field trips to historical sites in Pyongyang, among other projects.


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Sunday, October 17, 2010
The Brothers Bloom - 2008
I'm currently doing a Potluck Movie Pick with the gang over at Anomalous Material. Red set up a great idea where we all nominate movies from the Netflix instant catalog and then everyone is assigned a movie they have not seen.
Chris at Casta La Vista picked my movie for me, The Brothers Bloom. I remember seeing the trailer for this movie awhile back. It has three actors I love: Mark Ruffalo, Adrian Brody and Rachel Weisz. How could it not be great? However, it did seem to have a stylized kind of look to it and I thought it could go either way. I figured I would wait to see if it had good buzz. Well, it basically came and went.
In trying to find the negative aspects of this film, I will say that maybe people found it too slow paced and the settings a bit confusing. Certain settings and the characters' clothing, made it appear that this film was set in the past. However, they had backpacks, cell phones and karaoke. It's chance you take when you do something so stylized. A narrator and comic-book like graphics can be a real turn off to an audience. I, though, loved the look and feel of this movie and none of these aspects bothered me. Unfortunately, I guess there wasn't wide enough appeal at the box office.
Stephen (Ruffalo) and Bloom (Brody) play the Bloom Brothers. Orphaned at a young age, the two brothers bounce from foster home to foster home. Ruffalo, as the older brother, hates this life and resents the other children and the carefree lives they flaunt so innocently. Brody, on the other hand, wants nothing more than to fit in and live a normal life. The constant for Stephen (Ruffalo) is his love for his younger brother. He wants nothing more than to give him what he wants. At a young age, he begins to concoct "cons" and finds he's quite good at cheating people out of their money. Bloom (Brody) comes alive in cons because it allows him to pretend he has a completely different life. This lifestyle works for Bloom (Brody) for awhile, but it's still not the true, honest, quiet life he craves. He desperately wants out of the con-man life, but Stephen, who loves it all, keeps pulling him back in. In typical con-movie fashion, he convinces Bloom to do one last job, to heist the very rich and very lonely Penelope ( Rachel Weisz).
Weisz is simply adorable! She lights up the screen and is creatively crazy with intelligence. Audiences rarely get female characters in these types of films that aren't insipid and unbelievably idiotic. Penelope may be the Bloom Brothers "mark," but she's no dummy. In addition, Rinko Kikuchi as Boom Boom, is very cool, powerful and in control of her fate at all times.
The driving force of the story, though, is the relationship between the brothers. Mark Ruffalo once again turns in a fabulously believable performance. As I've said before, he makes it look so effortless that I think people take his talent for granted. Brody plays off of him effectively and you can feel his angst in loving his brother, yet desiring a normal, criminal-free lifestyle. It's hard not to be touched by their deep affection for each other. Stephen strives for nothing more than to make his baby brother happy.
By the end of the film, I felt more attached to the characters than I realized. I had a fun time hanging out with The Brothers Bloom and I hope more people will check this film out. Thanks Chris!
4 comments:
- Chris said...
Really glad you enjoyed this - it has been one of my highlights this year. I found the film to be wonderfully romantic and whimsical and loved the fact that it felt like a thirties/forties escapade in the present day.
Completely agree that Weisz is nothing short of adorable in this movie - I've always rated her and I this movie just went to further what I already knew.
Let's hope you enjoy the next movie you get as much (see AM for my thoughts on your movie!)
- October 17, 2010 at 11:28 PM
- Dan said...
I really enjoyed this one. And Rachel Weisz is fantastic - her career best performance for me.
- October 18, 2010 at 6:10 AM
- ruth said...
Unfortunately I can't participate on the dvd potluck for now, too many in my queue I haven't even got around to seeing. I've heard good things about this movie, I might check it out one day. Y'know, I don't think I have seen too many Mark Ruffalo movies... if you have to recommend an essential viewing, what would it be?
- October 20, 2010 at 9:46 AM
- Colleen said...
Hi Ruth! I think two films highlight his early work well.
You Can Count On Me &
My Life Without Me
I do think he'll get a Oscar nom for his performance in this summer's The Kids Are All Right.
Don't worry, my Netflix queue always hovers around 500!
- October 20, 2010 at 9:52 PM


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Listen to Hudson Mohawke's 'Satin Panthers' EP Now
Next Tuesday, Warp will release the first record to come from Glaswegian DJ/producer Hudson Mohawke since his debut LP, 2009's Butter, but before the Satin Panthers EP drops, you can hear the whole thing now. Below, you'll find a YouTube player streaming the five tracks that make up HudMo's 16-plus-minute release. You can pre-order your copy of Satin Panthers EP here.