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Yoga and Health are closely related. Yoga is a popular aid in improving both physical and mental health. This is basically the most common goal of people who practice Yoga – for health reasons. They want to ease their back pain, find a method to ease stress, or learn ways to deal with their health problems.Yoga practice helps to bring about total relaxation of the body and the mind, which enables healing to occur at a deeper level of the human personality.The healing science of yoga is a centuries-old tradition of practices for personal fulfillment and self realization, while living a healthful and stressfree life. Modern medical research suggests that correct and regular practice of Yoga can help prevent or treat many types of ailments while promoting general well being.Yoga provides a holistic approach that benefits every system in the body without the danger of adverse side-effects.Yoga has proved itself as the factor to regain health and remain juvenile. Even in the Western World there is a wave of persons practicing Yoga in their daily life. There are success stories where individuals have sorted out their issues and manage stress through yoga. Yoga in fact is an ancient technique to optimize the mind and body and maintaining the health equilibrium. Today in the USA alone there are several Yoga centers where numerous peoples from all classes and standards are practicing Yoga.Endocrine System: Yoga helps improve the functioning of the endocrine system that regulates metabolism and growth. Regular Yoga practice can be of immense in dealing with various health problems including diabetes and obesity.Health benefits of YogaFrom the physiological point of view, prolonged yoga practices can cure pulse rate decreases, respiratory and blood pressure dysfunctions, it can contribute to stabilizing the nervous system equilibrium, to normalizing gastrointestinal functions and endocrine function, to increasing the joint range of motions, endurance level, energy level, immunity to diseases and cardiovascular efficiency, to improving eye-hand coordination, reaction time, dexterity skills, depth perception, sleep, etc.Respiratory System: Yoga helps manage respiratory ailments as well as the various physical and emotional factors that aggravate or trigger the problem.Digestive System: Yoga helps you deal more effectively with various digestive disorders including heartburn and irritable bowel syndrome.Regular performance of meditationThe body is linked to the mind. Many of the diseases of this era are psychosomatic. Stress and anxiety take their toll on our physical health. Meditation is a mental exercise which, among other thingsScience Articles, allows a person to detach him or herself from the worries of life
Monthly Archives: September 2017
A Healthy Combo For Healthy Life
Yoga for most of the people happens to be a great source of keeping themselves fit with its incredible body postures called asana. However these asanas are only a small part of the yoga. This ancient practice of yoga boasts of its origin from ancient Vedic testaments. We tend to limit the scope of yoga by considering it a mere collection of exercises. But Vedic testaments say that it was originally meant to serve much greater purpose of unifying human souls with eternal power or God. And yoga meditation happens to be the only way of elevating your spirit so that you could unify yourself with Almighty. Your soul's unification with Almighty brings eternal peace and tranquility to you.
If you are not performing meditation instructions of yoga along with your daily asana practice, you are likely to not get much of the yoga benefits. Different yoga practices don't offer you separate solutions instead yoga works well when all its integral parts are practiced simultaneously in an orderly manner. This is the way yoga offers holistic health improvement. That's why meditation must be incorporated in your yoga routineFind Article, it works as a stress buster and brings in mental rejuvenation.
Yoga offers various ways of meditation that could be performed with other yoga practice. More higher forms of yoga such as kudnalini Yoga and Raja Yoga are said to offer complex medication practices but once you get accustomed to these practices you would achieve a higher state of mind and soul. Hot yoga offers you to perform meditation in a hot or high temperature ambiance that helps you disassociate yourself from the outside world. This practice helps enhance your mental productivity.
In today's fast moving world every one tries to improve his/her performance to keep up the pace with changes and in turn gets grappled with stress. Some of us simply perish due to our ignorance towards stress management techniques. In such a situation yoga meditation proves of immense help in stress management.
Ways are all the trend
Contains meditation, visualization, breathing and stretching, the pursuit of spiritual balance yoga, SARS began to heat up, but more and more fire. The indoor sports are the first choice of winter sports.
A good Yoga instructor is necessary to let you understand true meaning of yoga. Yoga originated 5,000 years ago, ancient India, the capital of the yoga studio are invariably invited Indian teachers to teach students the perfect yoga realm. Ritan Park Yogi Yoga instructor from India Mr. Mohan. His students, said Mohan Unlike domestic coach less emphasis on flexibility, he stressed that the experience of the power flow in the body, and teach when some long-tone singing, not only heighten the atmosphere of concentration, but also the effective interest rate adjustment. The capital of the famous cicada boat yoga studio to join hands with India Gandhi yoga and naturopathy, the introduction of certification training, promotion of authentic yoga practice and teaching methods.
Because many of yoga, Yoga means cohabitation, so it is not just superstition, a foreign coach. Recommended regular yoga training, perceived to increase his ability to judge the authenticity of yoga.
Since the winter after the first snow, skiing openly become the most popular recreational sports. Ski new information this year, is more handsome snow flying heroes will enjoy through arranged holiday leisure, Ski and Spa such combinations became an ultimate enjoy, in accordance with the online jargon, is ultra-FB (corruption) fitness tour.
Snow Ski and Spa FB group abroad is common, is to attract holiday leisure dotting pens. The past two years, the domestic conditions of the resort also learn the essence of foreign resort, the new outdoor hot spring pool, the introduction of the snow sauna, spa bath, and other projects, so that skiers after a two-hour snow sports in hot springs experience the pleasure of relaxation.
It is impossible to define "FB", it can be said that spas are the most comfortable choice after skiing. Just imagine, the total consumption in the ice after manual, then to forty or fifty degrees for a dip in the hot spring water, every pore in the flash open, the hot and cold mixed in sharp contrast, that difference of body pleasure, non-experienced unimaginable. Write here, I immediately wanted to escape from the cold, computer, join the FB swam in the ranks.
Spas should pay attention to physical condition, especially after strenuous exercise, reduced physical endurance, so spas water temperature should not be too high, should not be too long, otherwise prone to dizziness, nausea and other symptoms. At the same time pay attention to timely pay.
Red Manhood Protection From Cold Weather
Now that cold weather is blowing through, winter is definitely here. While even warm weather aficionados can find some things about the cold they like (hot chocolate, roaring fires, an excuse to stay inside and binge watch), it's equally true that even cold weather fans can find drawbacks. And for men, that includes getting a red manhood from freezing temperatures and bitter icy winds. Finding ways to keep the member sufficiently warm during these winter months is part of good male organ care.
Red manhood
Now, there's usually nothing wrong with a red manhood. Men who are fair-skinned tend to get a red manhood when it becomes firm, as the blood rushing into the engorged member causes a change in coloration. But sometimes a red manhood can signal a problem, such as being far too cold.
Anyone who has ever jumped into a pool of cold water has witnessed a cold red manhood � and one that is usually shriveled. But when the male organ is exposed to extreme cold temperatures for a prolonged time, it may actually get a little swollen and can experience extreme pain.
In some severe cases, a red manhood may be an indication of frostbite (or frostnip, an early stage condition of frostbite). Frostbite is accompanied by a numbness (lack of feeling or deadened feeling), swelling, blistering and fever, although not all men may experience all of these symptoms. If a man suspects he has a frostbitten member or other body part, he should seek medical attention. Severe frostbite can destroy tissue and in extreme cases may lead to amputation.
Keeping warm
To help fight that winter cold, there are several ways to keep the manhood warm during the winter.
�Don't go commando. First and foremost, men who habitually walk around without underwear should suspend that habit when venturing out into winter weather. The cold weather can be too dangerous to male organ health, no matter how nice the feeling of freedom may be.
�Stand in front of a fire. Spending a few minutes in front of a fireplace can help warm up a member so it withstands the cold better during its first minutes outside.
�Give the member a rub. Similarly, taking a couple of minutes to rub and massage the manhood before tackling the cold can be beneficial. This will get the blood circulating and help deflect the initial cold.
�Tuck it in. If he is only going to be outside for a few minutes, a guy can try tucking his manhood between his legs for extra warmth. However, since it will pop out relatively quickly, this is a very short term solution.
�Layer up. Doubling up on underwear is strongly advised. Just as a guy may wear a shirt, sweater and coat to combat the cold, so should he consider wearing more than one pair of underwear. The bottom layer should be tight briefs, an athletic supporter or compression shorts, each of which will fit the male organ more snugly.
�Go thermal. It can also help to wear thermal underwear, which may add an extra layer of warmth to the region.
�Investigate wind briefs. Many runners wear wind briefs, specially designed underwear with an extra layer of protection in the midsection.
�Wear a member warmer. A man can invest in an actual knitted member warmer � or simply wear a (clean) sock over the organ when temperatures get frosty.
Taking steps to prevent a red manhood due to cold weather pays off. So does taking steps to ensure overall male organ health, such as regularly applying a top drawer male organ health crme (health professionals recommend Man1 Man Oil, which is clinically proven mild and safe for skin). For best results, a guy should select a crme that is going to �cover all the bases� by including the major vitamins necessary for member health promotion � A, B5, C, D and E. In addition, the crme should include L-arginine, an amino acid which helps manhood blood vessels expand so they can accommodate a greater flow of blood.
Increase Yoga by Finding out
Moreover, this uncomplicated information can greatly enhance your feeling of objective as you bring the washing of your yoga exercises mat into your common yoga exercises. Normally, the best way to go is to adhere to the manufacturer's information on washing the bulk yoga mats, but you can regularly just apply the mat gently with a washing remedy, and when it is incredibly dirty you can drain it in heated, water and soap for a bit of time. One of the themes of yoga is the idea of convenience. In convenience, one can often discover a feeling of relaxed and even lighting. There are a lot of ways to live yoga-like way of life when not at the yoga exercises studio room for physical yoga exercises. This can be through things like changing to a healthy, veggie design of eating, or it can be through learning how to fresh a yoga exercises mat. Changing your healthy program can have a large effect on your life in all areas. When we eat right, we regularly feel right. This feeling of health and fitness results in our energy as well as mindset. The idea of convenience present in yoga exercises can be greatly made apparent in a veggie diet.
here is a saying that cleanliness is next to god lines In yoga exercises, learning how to fresh a bulk yoga mats is going to really be a main aspect of your path in yoga exercises. It has to do with developing wedding and getting rid of from content things to the physical. In other terms, a dirty yoga exercises mat can represent the toxins and other radicals in the whole body, which yoga exercises helps to overcome. In this way, knowing how to clean a wholesale yoga mat can become a wedding that you carry out after every yoga exercises session. You can think of it as aspect of the wedding that you have experienced bodily, and which now you are bringing into your content environment. Yoga gives a wonderful way to center and ground you through cadenced respiration and extending. It is a structure of habit and routine that increases both the mind and the whole body. To go even further, into the holy area, it also improves the soul. It is said that the whole body contains factors of power referred to as chakras, and these factors of power come into settings when one is practicing yoga exercises. What is encouraging and attractive about yoga exercises is that it is padded in practice. In other terms, it is not just about respiration and extendingPsychology Articles, but also about a lifestyle.
Planning your dream yoga vacation
If you are trying to get away from the myriad of problems and pressures that ravage your living then you surely looking for a vacation that involves re-creation and re-juvenation. And what better way than to treat yourself with a yoga vacation!
Yoga vacation is a great opportunity to unwind and detach yourself from your frantic day-to-day routine. Unlike regular vacations one can look forward to multiple activities that a yoga retreat offers. However, your dream yoga vacations are the ones that are carefully planned for in order to gain the maximum out of it.
The first and the foremost is to have an overview of your trip. Carefully go through the facilities that a yoga retreat offers. As some retreats do not offer accommodation and have strict schedules, whereas others offer the guests free time to spend as they choose.
The second step is to decide the type of retreat that suits convenience. Strict yoga practitioners might want intense yoga sessions during their stay. For the ones who want to relax would prefer various activities that help them enjoy a normal vacation with no strict itineraries.
Third is to consider the location and the budget. Plan your stay according to yourbudget, as all retreats do not offer all the facilities. And the ones that do offer vary in their quality. Opt for locations that are exotic and away from cities.
Next step is to inquire about their techniques. There are number of yoga styles and techniques that are not offered by many retreats. Be sure in picking a destination that practices the correct form of yoga so that you do not squander your vacation. This definitely helps you to limit your choices when it comes to selecting the location.
And the last factor to be kept in mind is the size. Some people find the best retreats are the ones where relation between the student and the instructor is on one-to-one basis. Whereas other retreats are larger in size attracting many guests. Depending on your comfort zone, you can select your destination.
Yoga vacations are the best enhancers to regain your energy levels, calm your mind, body and soul. They are an excellent alternative to a traditional vacation. At the end of your vacation you are not only charged up and ready for challenges but are also blessed with a broader vision towards life in all arenas. Yoga helps you dwell in positive soul that keeps you elevated from the worldly attachments. It does not compel you to become spiritual but it helps you to hear your inner voice sonorously.
Start Learning Yoga Moves from Today
The first option is to join a yoga class in your locality where a yoga trainer will guide you step by step in learning yoga moves easily. The second option is to join online yoga classes where you can start learning yoga moves with the help of internet.
As most of people are short of time due to their hectic schedule and busy work life, these online yoga classes are very beneficial when it comes to achieve complete holistic health in a natural way without getting worried about time wastage. If you are following a book to learn yoga moves then it can be a good idea but books only explain still pictures which are unable to elaborate the entire set of yoga moves. In television, they don't teach the entire exercise and you need to fix a schedule for the programs and if you miss that you will rarely gets an opportunity to do it again.
However, in the case of online classes, you can fix a schedule depending upon your time availability and you will learn performing yoga moves step by step on your screen. And if in between any query arises, you can also ask the yoga instructor for help. It also helps you in selecting yoga moves that are ideal for your body.
Rest of the thing depends upon your concentration and energy level. If you are willing to get rid of several health issues in a traditional and natural way, then it is best to go for online yoga moves.
Divine Wellness
, the most comprehensive resource for yoga exercises and posturesFree Articles, offers yoga moves online via HD video conferencing. It helps you to learn Hatha Yoga in an elegant way.
Bulk Yoga Mats For Healthier Workouts
Yoga is a work out that almost everyone should take up some time or another. Bulk yoga work out will develop your durability and versatility if you select to do it regularly. Another amazing element is the inner serenity it will carry to your thoughts. To get the very best bulk yoga exercises you need an appropriate bulk yoga mat. One of the best ones available on the industry is the Gaiam bulk yoga mat. The Gaiam bulk yoga mat is created by the organization of the same name. It is centered out of Denver. Their tag line is "Lifestyle Company." It is important that comes to thoughts when discussing of a these items is the point that each and every one is created up of reprocessed content. They know that a sticky yoga mat won't last permanently, so they create top quality pads out of reprocessed components. This is a large plus on the globe of sticky yoga mat.
They come in a wide range of forms, shades and thicknesses. To buy the one that is right for you, it is best to think about your system shape, along with how extreme your sticky yoga mat exercises are going to be. A mat that is at least 4-millimeters dense is usually the conventional for most sticky yoga mat lovers. However if you are a very slim individual – or someone who is more on the delicate part, then it is perfect to look into wider ones. Of course Gaiam creates several styles and thicknesses, so you will have more than enough to select from. The organization provides several different choices to buyers. If you are a web consumer no issue, basically check out their web page up and take a look around. More often than not you will also come across some excellent discount rates on the pads. Gaiam sticky yoga mat pads have a experience and structure as opposed to any other sticky yoga mat available. The grip available on these items is second to none as well, offering outstanding grip even the slipperiest of surfaces.
There are plenty of item choices available to individuals who get involved in the art of sticky yoga mat. These pads are second to none, and we wish that this content allows you to at least take a look at the different pads that the organization has to provide. Aside from having strong origins in Hindu myth, competition epidermis sticky yoga mat exercises pads had all of the qualities yogis needed in a mat. They were large enough for realistic utilization yet lightweight when packed away. When the yogi desired to use his competition epidermis for the exercise of Hatha yoga exercisesBusiness Management Articles, it normally unrolled smooth without styling up on the finishes. The fur offered insulating material and just enough cushioning for protection without being soft and the leather like epidermis side of the competition epidermis mat offered a perfect non-slip surface. The yogi could get into and sustain even the most difficult yoga exercises positions (asanas) without worry of his mat falling out from under him.
The World Goes Gaga Over Yoga
Furthermore yoga has also proven its worth in shooting out stress and anxiety that are widely prevalent. In fact, if you keep practicing Yoga on a regular basis, you are very likely to remain stress free for the whole life. There could not be a better natural stress reducer than yoga.
A good number of workaholic folks have been found falling prey to stress and anxiety and usage of medications seem to worsen the situation. That's why people are rather keen to follow natural ways to control stress. It's just because of that millions of Americans have taken refuge in Yoga to fight their stress and anxiety. Not only in America but in Europe and other continents as well, Yoga is increasingly becoming popular as stress reducer.
Yoga curbs stress by bringing tranquility and peace of mind. Your mind experiences complete rejuvenation with yoga exercises. There are certain yoga asanas (postures) that are specifically meant to provide relaxation to mind and greatly contribute to stress reduction. For example, corpse posture of Shavasana. Other relaxation providing yoga poses equally contribute to mental peace.
An aggravated stress could be effectively cured yoga dhyana or meditation. Meditation offers a long term solution to people who are prone to stressful situations. In today's life you can't avoid stress, so stress management becomes a prerequisite. That's when Yoga proves it's efficacy as stress management tool with its wider range of exercise practices.
What is particularly beneficial in curbing stress is hot Yoga exercises. You are made to exercise in soared temperature. Once you are through with a session of hot yoga, you feel completely rejuvenated.
You may go for practices like Ashtanga and kundalini, they are quite helpful in freeing you from tensions. Anxiety could be successfully eliminated with regular practice of Vinyasa.
Various breathing exercises are of special significance in preventing stress. They are easy to practice and could be made a part of your daily schedule.
A consultation with an experienced Yogi would give you a detailed insight into yoga poses and exercises that are of help in keeping you mentally fit in order to cope up with stressful situations.
So take up yoga practices to keep yourself stress freeArticle Search, it's not only you but the entire world who is looking at yoga as a sure remedy of stress.


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Up to 25 scholarships awards of $1,000 for summer programs and $2,000 for spring and fall programs are available for undergraduate students studying in Mexico. In support of the UC-Mexico Presidential Initiative, UCEAP is proud to announce that $50,000 in scholarships will be set aside in 2019-20 for students studying abroad with UCEAP in Mexico. To apply for a Mexico Initiative Scholarship, complete the UCEAP Promise Award application. Your application will be considered amongst the applications of other students going to Mexico for the Mexico Initiative Scholarship. If you do not receive a Mexico Initiative Scholarship, your application will be considered for a UCEAP Promise Award. You cannot receive both a Mexico scholarship and a UCEAP Promise Award for the same term.
Which UCEAP Spanish Language Requirements Apply to Me?
The Spring (Advanced) option does not include an Intensive Language Program (ILP). Students participating in this program must be mature and have strong Spanish skills to prepare themselves to go directly into courses with local Mexican students and taught in Spanish by UNAM professors.
Visit your Campus Study Abroad website for program-specific deadlines:

subset: commoncrawl


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Countering deliberate misinformation hasn't been a big issue for me in 12 years of professional business writing.
Spin? Sure. Advantageous positioning? Of course.
But no outright lying.
Moving into the Sustainability world has introduced me to a new level of complicated. I see fear-mongering, cherry picking, rewriting history, and what looks to me like plain old lying.
Considering what's at stake, I'm not surprised. The Climate Change conversation combines fantastically detailed subject matter, ferociously entrenched viewpoints, and the howling wind of information overload. There's a lot of money to be made and power to be retained. Winners and losers.
So what's a communicator to do? Learn to state a strong case, call bull when I see it, and debunk with civility.
Via SkepticalScience.com:
The Debunking Handbook is a guide to debunking myths, by John Cook and Stephan Lewandowsky.
The Debunking Handbook, a guide to debunking misinformation, is now freely available to download. Although there is a great deal of psychological research on misinformation, there's no summary of the literature that offers practical guidelines on the most effective ways of reducing the influence of myths. The Debunking Handbook boils the research down into a short, simple summary, intended as a guide for communicators in all areas (not just climate) who encounter misinformation.


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WA 008 Swarovski Earrings (New!)
Unique colors and designs created with orange-red / black swarovski ( 4mm / 6mm ) and black japanese beads.
Wires and hooks are imported products and of better quality.
Average length of earring approx. 4cm - 6.5 cm.
Choose any 1 pair for RM6.00 OR 2 pairs for RM10.00


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DAC Collection Artist Information
Charles Courtry (aka Charles-Jean-Louis Courtry)
French printmaker and illustrator
Artist ID number in the Union List of Artist Names®: ULAN 500045190.
The ULAN link above leads to a cataloging authority record at the Getty Research Institute.
Objects related to Charles Courtry (aka Charles-Jean-Louis Courtry):
|Charles Courtry
|Portrait of Edouard Manet, ca. 1862
|Etching on leaf in bound volume
|Charles Courtry after Jozef Israëls
|A Painter Etcher (Portrait of Jozef Israels), 19th century
http://dac-collection.wesleyan.edu/art35560 is a persistent link to this page with no user-session information.


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Resources for fixing up sewing machines
It amazes me to look at the engineering in the old machines. They were so intricate and yet they have held up over such a long time. My old Singer 403 was all metal even the gears. I also have an old Necchi Nora - it has a broken plastic stitch length adjuster so it is now a parts machine - The Bernina and the Elna have nylon gears. I guess the sewing machine companies were fooling around with plastics and nylon back then - The machine works are a wonder though. Each of them is different in how they work. It totally fascinates me. Then I look at an old Japanese straight stitch. No nonsense there. It is so amazing how these are put together!!! You sure don't see much when you look in the new plastic and stamped metal machines - is it any wonder they don't hold up and you can't get anybody to repair them??? Yeah I have a bunch of old machines. Yeah the DILs think I'm a hoarder... well, they are correct. (AND I hoard fabric too - OH, the shame of it all...) I guess I can't bear to see those old machines discarded by the same people that talk about everything being 'green'... Wanna go green? Get a vintage sewing machine and learn to use it - re-make some clothes instead of discarding them. Ok you might have to piece them together or make t shirt quilts or make some quilts out of old clothes or buy fabric at a yard sale - BUT go green!


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After Towers Watson published its annual predictive modeling survey results a couple weeks ago, I assumed it was well covered.
My assumption was wrong. I realized that the "coverage" was mostly cutting and pasting the firm's news release. Being familiar with the past studies, my goal here is to give this important survey the deeper coverage it deserves. The study, called, "2012 Predictive Modeling Benchmarking Survey: Advances in Implementation," can be found here.
Previous studies revealed the benefits of predictive modeling and its use by insurance line. The new study places personal lines and commercial lines into their own buckets. My focus is on commercial lines.
Being a certifiable comp nerd, I had to know how it is progressing in workers' compensation. To find out, I contacted Brian Stoll, one of the study's authors, who is a source I have relied on for my predictive modeling articles. He was kind enough to supply the informationshownin the chart above.
Ninety percent of the property/casualty insurers surveyed said
bottom-line performance improvements were the motivation
for applying predictive modeling.
The graph above shows that insurer use andor interest in using predictive modeling for workers' compensation continues. Keep in mind that the study's mix and amount of responders changes for each study. This year's results include smaller insurers who are likely not yet in a position to apply predictive modeling.
Ninety percent of the property/casualty insurers surveyed said that bottom-line performance improvements were the motivation for applying predictive modeling.
This confirms the assertions I make in myblog, Predictive Modeling Is Here to Stay, which was published one day before Towers Watson's results were released.
Most carriers report bottom line profitability from predictive modeling. Commercial lines carriers have seen positive effects in: rate accuracy (83 percent), loss ratio improvement (72 percent) and profitability (61 percent.)
Bottom line positive impacts for commercial lines carriers are: renewal retention (39 percent), market share improvement (33 percent), and expansion of underwriting appetite (22 percent). The report says that given trends, standard commercial lines will likely achieve benefit levels even more over the next few years. I agree. Commercial lines insurance has been following the lead of personal lines all along, so as efforts mature, so will results.
Another important point: midsize and larger employers report more favorable bottom line results, particularly in loss ratio improvement and profitability. "This is likely a result of first-move advantage," the study says.
Other significant tidbits are:
- Commercial lines carriers focus more on loss ratios than the frequency/severity models used by personal lines.
- Predictive modeling continues to have barriers including access and cleanliness of data, IT limitations and "people/cultural issues."
- It appears that carriers of all the p/c lines surveyed have not yet taken advantage of reducing manual renewal costs or focused their manual underwriting activities on higher-premium or more complex accounts.
The study was based on 63 insurance executives from the U.S. and Canada. Responding companies represent a significant share of the U.S. P&C insurance market for both commercial lines insurers (21 percent) and personal lines carriers (17 percent).
(Note: This is part V of my blog series on What Employers Should Know About Workers' Compensation Predictive Modeling.)
Be the first to know! Just click on the "follow" button on the bottom right hand of this page.
Related Blogs:
Predictive modeling will more accurately reflect an employer's specific experience. Click Here
- Predictive Modeling Is Here to Stay Click Here
- Predictive modeling and premium auditing Click Here
- "Predictive Modeling Is Here to Stay" Discussion on the LinkedIn Group: Workers Compensation Roundtable Click Here
- Predictive modeling and Your Insurance Agent and Broker. Click Here
- Predictive Modeling 's Impact on Agents and Brokers—and Their Clients Click Here
- Workers' Compensation Predictive Modeling Click Here
- Workers' Comp Predictive Modeling and Self-Insured Employers Click Here
Related Articles:
- Workers' Comp Predictive Modeling Comes of Age Click Here
- Predictive Modeling 's Impact on Agents and Brokers—and Their Clients Click Here


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Palo Alto Center
The PAMF Palo Alto Center provides a full range of primary care services and more than 50 specialty and sub-specialty medical services, including state-of-the-art diagnostic and imaging technologies, allergy and immunology, dermatology, gastroenterology, neurology, OB/Gyn and sports medicine.
Palo Alto Center
795 El Camino Real
Palo Alto, CA 94301
Main phone: 650-321-4121
Google Map
Floor map of the Palo Alto Center buildings and department (pdf, download Acrobat Reader if you don't have it) -- if you are unable to view this document, volunteers are available to assist you at the clinic.
On busy days, it can be a challenge to find a parking spot in the underground parking structure. Please take advantage of the additional parking above ground, right behind the clinic on Urban Lane. It is still a short, easy walk to the main clinic and other buildings on our Palo Alto campus.
Phone directory for specialty departments
Center hours:
Monday through Friday, 9 a.m. to 5:30 p.m.
Saturday, 9 a.m. to noon
Doctors' office hours vary, so please ask the receptionist about a doctor's schedule. For your urgent needs, telephone operators are available 24 hours a day.
Urgent Care 650-853-2958
7 a.m. to 8 p.m., 7 days a week (No appointments)
Pediatric Urgent Care -- 650-853-6558
Monday through Friday, 7 a.m. to 9 p.m.
Saturday, Sunday & most holidays, 8 a.m. to 8 p.m.
There is "walk in" without an appointment, but please be aware that patients with appointments will generally be seen first, depending on urgency.
Pharmacy 650-687-0154
Monday, 9 a.m. to 7:00 p.m.
Tuesday through Friday, 9 a.m. to 6:30 p.m.
Saturday, 9 a.m. to 1 p.m.
Community Health Resource Center
Monday through Friday, 9 a.m. to 4:30 p.m.
Drop-in basis or by appointment.
Monday, 6:30 a.m. to 7:30 p.m. - extended hours
Tuesday through Friday, 6:30 a.m. to 6 p.m.
Saturday, 7:45 a.m. to 12:30 p.m.
Monday through Friday, 9 a.m. to 5 p.m.
Monday, 7:30 a.m. to 7 p.m.
Tuesday through Friday, 7:30 a.m. to 6 p.m.
Saturday, 8 a.m. to noon
Breast Imaging Center - 49 Wells Building
- Dedicated mammographers and fellowship-trained breast radiologists who work closely with a multi-disciplinary team of cancer specialists
- Five mammography rooms for both screening and diagnostic mammography
- Two ultrasound rooms and one stereotactic biopsy room
Driving Directions
Directions to the Palo Alto Medical Foundation from Highway 101: Take the Embarcadero Avenue West exit towards Stanford University. Turn right onto El Camino Real. The Palo Alto Medical Foundation is located on the right, past the Town and Country shopping center.
Directions to the Palo Alto Medical Foundation from Highway 280: Take the Page Mill Road exit. Go east on Page Mill. Turn left on El Camino Real. After the Embarcadero Road intersection, the Palo Alto Medical Foundation is located on the right, past the Town and Country shopping center.
Scheduling an Appointment
650-321-4121 or call the department directly
Monday through Friday, 8 a.m. to 5:30 p.m.
Saturday, 8 a.m. to 11:30 a.m.
Routine Appointments
An appointment is required to see a physician at PAMF. You can schedule an appointment either in person or by telephone. Once you have selected a primary care physician, you can call his or her department directly. The main Center number is 650-321-4121.
If you must cancel an appointment, please call at least 24 hours in advance when at all possible. You can call PAMF at any time and leave a cancellation message with the operator at 650321-4121.
Urgent Appointments
Urgent appointments are visits for acute problems which may need to be evaluated or treated within 24 hours. Call your physician's office first to determine your need to be seen that day. The nurse will schedule an appointment or direct you to either the physician on-call in your physician's department that day or to the Urgent Care Center or Pediatric Urgent Care. The departments of Family Medicine, Internal Medicine, Pediatrics and Psychiatry provide on-call physicians daily to meet the need for urgent appointments.
Specialist Appointments
A specialist is a physician who practices medicine in a specialty area, such as cardiology, orthopedics, dermatology and urology.
Most patients with health insurance plans that do not require care to be managed by a primary care physician (PCP), such as traditional Medicare or indemnity insurance (also called Fee-For-Service) plans, do not have to obtain a referral from a PCP to see a specialist. You may want to review your plan coverage guidelines to determine whether or not your health insurance plan requires specialty care referrals.
HMO Patients: All specialty care is coordinated by your PCP. Unless your PCP has directly referred you to a PAMF specialist, any services provided by a specialist, even within PAMF, may not be covered by your managed care plan. Once your PCP has referred you to a specialist, you may call that specialist's department to schedule an appointment. If the referred specialist is at PAMF, you may call the specialist's department directly 24 hours after the referral has been made to schedule an appointment.
PPO Patients: Under most PPO plans you have the option to coordinate your specialty care through your PCP or you may self-refer yourself for specialty care services. When you self-refer for specialty care services or when you obtain specialty care services from physicians who do not participate in your plan's provider network you may be responsible for higher out-of-pocket costs (i.e., co-payments or co-insurance).
Point of Service (POS) Patients: Most POS plans give you different options for accessing health care services. One option is to use the plan like an HMO, where you receive your health care services from your PCP and obtain referrals for specialty care services. When using your POS plan like an HMO you will be responsible for the HMO benefit-level co-payments. Your other option is to use your health plan just like a PPO where you can access care from either a participating provider or a non-participating provider, without coordinating care through your PCP or health plan. When accessing specialty care services under the PPO option of your POS plan, you are generally financially responsible for a deductible and/or a percentage of your bill.
Referrals Outside the Palo Alto Medical Foundation
PAMF can provide you with primary and specialty care in most instances. On occasion, we may refer you to a specialist outside PAMF.
Most patients with health insurance plans that do not require care to be managed by a PCP, such as traditional Medicare or indemnity insurance plans, do not have to obtain prior authorization to see a specialist outside of PAMF. You may want to review your plan coverage guidelines to determine whether or not your health insurance plan requires specialty care referrals and/or authorizations.
HMO Patients: If you are referred for services outside of PAMF, your PCP is still responsible for coordinating your care and you must resume care with your PCP once the outside specialist has completed an authorized service or treatment.
PAMF has developed relationships with various specialty physicians in the community. If your PCP determines you require care that PAMF cannot provide, your PCP will request a referral to a specialist outside PAMF. Requests for referrals to outside specialists will be reviewed by the Managed Care/UM department. Except in urgent situations, please wait to schedule your appointment with the specialist until you receive a confirmation letter. Following these procedures carefully will prevent possible denial of payment that could result in you being financially responsible for payment. The specialist will also be mailed a notification of the denial or authorization. If you have questions, please contact the Managed Care/UM department at 1-855-263-4067.
PPO Patients: Generally you are not required to coordinate care through your PCP if you self-refer to an outside specialist. However, your health plan may require that you obtain prior authorization for certain specialty care services.
POS Patients: If you access HMO benefits under your POS plan, your PCP will be responsible for coordinating your care and you must resume care with your PCP once the outside specialist has completed an authorized service or treatment. When using the PPO benefit option of your POS plan, you generally are not required to coordinate care through your PCP when self-referring to an outside specialist. However, your health plan may require that you obtain prior authorization for certain specialty care services.
Rescheduling Appointments
If you are unable to keep your scheduled appointment, please notify your physician's office. This will allow the physician to see someone else who may need an appointment.
Coming in for Your Appointment
Registration is located in the main lobby at 795 El Camino Real.
New Patient
New patients should arrive 20 minutes prior to their first scheduled appointments to allow time for the registration staff to obtain personal and insurance information.
Patients without insurance or residing outside of the United States will be asked to make a deposit at the time of initial registration. Referrals from outside physicians to Foundation specialists should be presented at registration.
Current Patient
Please bring your health-insurance-plan card with you for every visit. It is important to inform the registration staff of changes in name, address, insurance and phone information
In life-threatening situations, such as a heart attack or traumatic injury, dial 9-1-1 for fast paramedic assistance, or go directly to a hospital emergency room. If possible, notify the hospital staff about your insurance coverage and the name of your PCP. Please notify your PCP within 24 hours.
Emergency Situations When Traveling
Call the Center first for instructions before seeking care elsewhere, unless the catastrophic nature of the illness or injury first requires emergency treatment. Please try to ensure that your PCP or the Center is notified of the emergency as soon as possible so the physician can coordinate your care.
The Center's telephone operators are available 24 hours a day at 650-321-4121 and can help you reach a physician.
Usually, notification must be made within 24 hours. If you are unable to do this because of medical incapacity, then a family member or other responsible party should contact your PCP within 24 hours. Since requirements vary from plan to plan, please read your membership information packet to become familiar with the health plan's requirements.
Urgent Situations Locally
The Palo Alto Urgent Care Center, located at 795 El Camino Real in Palo Alto, is available for urgent situations. The Center is open daily from 7 a.m. to 9 p.m., including holidays. During the Palo Alto Center's general hours of 9 a.m. to 6 p.m. Monday-Friday, it is best to contact your primary care physician before going to the Urgent Care Center or in Pediatric Urgent Care to determine whether it is the best place for you to receive care. (Physician's office hours vary, so please ask the receptionist about a physicians schedule)
Urgent Care co-payments are higher than normal office visit co-payments. After 6 p.m. and on weekends, you will be charged a higher "emergency" co-payment. During normal Centers hours, if you obtain care from the Urgent Care Center without first being referred to or receiving authorization from your primary care physician or advice nurse, you will be expected to pay a higher emergency co-payment.


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Many parents keep tabs on the frequency and consistency of an infant's bowel movements. Any change in an established routine brings anxiety and possible visits to the doctor. When constipation is diagnosed and intervention is required, the pediatrician might suggest using a glycerin suppository.
Constipation is a problem that is common in infants and children, accounting for about 3 percent of pediatric outpatient visits. Although it is a worrisome situation for parents, there is rarely any underlying medical reason. In the first week of life, infants average about four bowel movements per day, tapering to 1.7 stools per day at age 2 and 1.2 a day by age 4.
Causes of Infant Constipation
Changes in diet that an infant experiences sometimes result in constipation. Starting formula after being breast fed or moving to more solid foods can lead to constipation. If you suspect your child is constipated, consult her doctor before taking action. Do not administer a laxative to any child under age 6 without the advice of a doctor.
Laxatives, products used to promote bowel movements, are available for either oral or rectal use. The rectal products are suppositories and enemas. Laxatives are grouped according to their methods of action. Some are stimulants, causing an increase in the contraction in the intestines. Others soften the stool, and still others increase the volume of stool.
Glycerin Suppositories
Glycerin suppositories are hyposmotic laxatives, meaning they serve as stool softeners by absorbing water from the surrounding tissues. They provide quick results, sometimes within 15 minutes. There are forms specially designed for infants and children. Because they are rectal products, the infant is not required to ingest anything, making this type easier to administer. Parents often choose these products because of the ease of use and quick results.
Do not overuse suppositories or other laxatives; otherwise, your child could develop a "laxative habit" and begin to depend on a laxative for a bowel movement.
Watch your infant carefully to ensure there is no adverse reaction to the glycerin suppository.
A dietary change could help prevent future bouts with constipation. Try adding water or fruit juice to an older infant's diet, or feed your child high-fiber cereals, such as barley, if solid food already is part of his diet.


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Next Episode of Posh Pawn is
From helicopters to Lamborghinis, mini-submarines and Hermes handbags, Posh Pawn uncovers the hidden world of high-end pawnbroking.
An ex-Chelsea footballer player turns up with some expensive Rolex watches, and James is put to the test when he's asked to evaluate a hovercraft used in a James Bond film
A divorcee from Newcastle wants to pawn her £185k necklace to pay for her children's private school fees. A Swarovski crystal-covered drum kit used on a Kylie Minogue tour gets Patrick excited.
Prestige Pawnbrokers boss James mixes business with pleasure as he meets an entrepreneur friend in Spain who's looking to get a £100k loan on his luxury 18-metre yacht
This episode features paintings by East End gangsters the Krays, and some fake watches cause a bust-up with staff
The staff are amused when a life-sized suit of armour and matching horse arrive at the new Hatton Garden shop. James gets stuck without a paddle on a canal barge.
James heads to Lanzarote for his biggest deal yet, the sale of a £1.5m yellow submarine. A rare Sex Pistols guitar puts Lawrence in a difficult position and a doting dad-to-be pawns his black Ferrari.
Can Kristin accurately evaluate a piece of jade that could be worth over £300,000? And Weybridge manager Jamo sells a 1930s classic car under the watchful eye of boss and car expert James.
A bumper-car collector looking for a loan visits the shop offering an impromptu test drive in the city. Patrick is star-struck when he deals with a bass guitarist who used to play with Eric Clapton.
Isy Suttie(Narrator)
James Constantinou(James Constantinou)
Looks like something went completely wrong!
But don't worry - it can happen to the best of us,
- and it just happened to you.
Please try again later or contact us.


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DNS Tect
Blue Sky Satellite Services, (712)-899-2343, Des Moines, Ia
Install and repair's for Dish Network.
Install and repair's for Dish Network.
Working to keep the store clean and catering to the customers needs and wishes to the best of my ability.
Dishwashing plates, prepping food for afternoon customers, refilling buffet for front of house.
Going door to door generating roof repairs leads for the company.
Outbound calls selling Charter packages for tv, Phone to existing customers.
Daycare provider for elementary age children before and after school.


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This was the fourth installment of Curves Rock Weekend and I can see clear evidence of the growth and evolution of this plus- friendly event which features everything from karaoke to an expo of some of the most sought after designers in the plus- community.
This year I had a chance to attend the Fashion Meets Curves brunch which provided media, stylists and bloggers the opportunity to hear first hand from some of the designers showcased during the runway show.
Ashley Stewart served as a sponsor for the weekend and Big Women: Big Love star Sabrina Servance was awesome as she encouraged attendees to embrace their beauty and curves as well as giving transparent insight into her own journey as a quirky, curvy girl with a unique sense of style.
Looks from Ashley Stewart
Style expert Denise Cadell also addressed attendees- Some of her best advice for being snatched? Select your shapers/ Spanx in one size smaller for ultimate silouette under your clothes.
I had several fan girl moments during the weekend as I had a chance to buy pieces from one of my favorite designers Courtney Noelle ( formerly Rum and Coke). Her items were deeply discounted and I fell so deeply in love with one of the dresses that I opted to wear it that evening.
Me rocking Courtney Noelle
The runway show is always the highlight of the show and featured designs from the likes of Tru Diva Designs, Ashley Stewart and Eyani Couture.
Check out some of the other looks from the Runway show:
Make sure you follow Curves Rock Weekend to keep updated on next years event.
Photo credit: Brian Hall, Luxe Glam Collective


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Visit Merlin at HP Palmtop Tour.
Visit MIRALab at the University of Geneva.
Contents © 1998 ACM SIGGRAPH All Rights Reserved Send your comments to SIGGRAPH 98 Online.
Just Act Natural
by John Dudley Miller
If you're one of the many people who aren't yet sure what synthetic actors are, let me give you a hint. You probably have seen them. In the movie "Titanic," some of the extras huddled on the deck of the slowly sinking ship were synthetic actors, computer-generated characters realistic enough to pass for humans. Fooled you, eh? And to think you cried such big tears over them.
You've seen another kind of synthetic actor if you've ever looked at the website for Hewlett-Packard's Palmtop computer. A cartoon-like version of Merlin the magician is just human enough to answer your questions while he explains the new machine's features. He can make 60 different gestures, and he responds appropriately even to messages off the subject, like "What time is it?" or "Say hello.".
The first widely-viewed synthetic actor was a virtual version of Marilyn Monroe, created a decade ago by Nadia Magnenat-Thalmann and Daniel Thalmann, the ground-breaking husband-and-wife professor team in Switzerland. Clips of the digital version of America's greatest heartthrob have played on TV stations around the world. Their 1987 book, Synthetic Actors, gave this emerging field its name.
These days Marilyn would be categorized as a special kind of synthetic actor, an avatar. Popular with web gamers, avatars are characters that represent the real people controlling them in a virtual environment. The term comes from the Hindu name for the several different human forms the god Vishnu took on when he appeared on Earth.
According to the SIGGRAPH 98 program, synthetic actors are the end result of "creating, acquiring, programming, and controlling realistic, real-time human behavior," like Marilyn sashaying or the "Titanic" extras pondering blue-lipped death in cold cyberwater. But the ones being discussed and demonstrated in Orlando actually stretch that core definition in two important ways.
Visually, this year's models run the 3D gamut from cartoon characters to realistic depictions of humans to artificial life objects, imaginary creations whose only limits are that they must follow basic life processes like evolution, breeding, and natural selection.
In terms of behavior, this year's synthetic actors range from brainless, totally controlled renderings like those found in traditional cartoons, to characters equipped with such powerful intelligent agent programs that they act autonomously, adapting to a variety of situations.


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T-Shirt Techniques has been creating the most unique screen printed designs since 1985. And not just Tee's, your custom corporate Logo, Sport activity apparel, community event design or anything you can imagine can now be accomplished with custom screen printing at T-Shirt Techniques. All the artwork, set-up, and screen printing is performed right there in their shop so turn-a-round is quick and reliable.
Need help in designing the right look? T-Shirt Techniques has two full-time graphic artists on staff To help you. To contact T-Shirt Techniques for a free estimate, please visit the contact us page.
Normal production time is 10 business days, however rush orders may be available. Additional costs may apply for rush orders.
There is a $25 setup charge for less than 24 peices.
Pricing can differ greatly on many factors. These include but are not limited to: total quantity, style of garment/material, color of garment/material, complexity of design, and number of colors in the design. Because of these varying factors, each order is unique and must be priced as such.


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Smart Advice for When You're Not Healthy
By Barbara Ballinger, REALTOR® Magazine
Think you won't need disability insurance before you retire? Unfortunately, the odds that you will are much better than winning the lottery. Nearly one-third of all Americans suffer a serious disability between ages 35 and 65, according to the American Council of Life Insurers in Washington, D.C.
Yet, only a small number of the self-employed buy it. Some say they're too busy to make the decision; some consider the premiums too pricey; and some believe they already have it in their worker's compensation. (They don't. Worker's comp helps you when you're at work and not if you slip on an icy patch outside your residence.)
Many financial gurus think you can't afford notto have it. But if you're responsible for your income, you won't have commission dollars flowing in if you're unable to work for an extended period.
Several books offer healthy advice about disability insurance, as well as health, life, and long-term care insurance. You should weigh the advantages vs. the costs of these insurance options, particularly as life expectancy gets longer. One rule of thumb: You don't need to buy different insurance policies from a single carrier, but having one person coordinate your benefits so you don't have overlapping coverage is smart. Following are five books to get you started:
- Working for Yourself: Law and Taxes for Independent Contractors, Freelancers and Consultants by Stephen Fishman (Nolo Press, 2002). Disability coverage can be tough for the self-employed to secure. Fishman, an attorney, provides a good tip to make the purchase easier: Show an insurer you operate a successful business. Some ways to do that are a list of employees, long-term contracts with clients, a detailed financial forecast statement with expenses and earnings, and good credit references. Another good tip is to carefully find out about an insurer's financial health (so you get funds if you need them) by checking its solvency through Best's Insurance Reports, Moody's Bank and Financial Manual, Standard & Poor's, or Duff & Phelps. The back of this book includes useful forms and documents. Buy this book from Amazon.com.
- Hassle-Free Health Coverage: How to Buy the Right Medical Insurance Cheaply and Effectively by The Silver Lake Editors (Silver Lake Publishing, 1999). This is a practical volume in a slim format that can be tucked into your briefcase or taken with you when interviewing insurance agents or brokers. It's full of information for anyone confused about buying the right insurance, in part because of the many changes in health-care delivery, the complicated jargon, and the great number of acronyms. Although its focus isn't the self-employed who buy insurance on their own, the book touches on this subject and provides enough background information to help a real estate practitioner make more informed decisions. Among its strongest suits is the chapter on key terms, acronyms, and definitions, such as UCR (usual, customary, and reasonable fees paid for specific medical treatments) or EP (the elimination period or time, usually expressed in days or months, during which benefits aren't paid). It also points out key features to consider when buying insurance. Example: the percentage of income provided by a policy after the EP usually is only 60 percent to 70 percent. Buy this book from Amazon.com.
- Insurance for Dummies by Jack Hungelmann (For Dummies, 2001). Being disabled is difficult enough without having the added financial drain and heartache of changing your lifestyle because you didn't have coverage to protect your monthly expenses, writes author Hungelmann, a certified financial planner and claims adjuster for more than 25 years. Hungelmann is a big advocate of avoiding risks, and writes, "Don't risk more than you can afford to lose." He strongly advocates disability coverage both for employees and the self-employed. Among the key points to consider when purchasing a policy are coverage for both incomes if you're part of a two-career family and need both paychecks to get by; enough monthly insurance to pay your essential bills but not so much that you cover expenses that you won't need when you're not working; as long an elimination period as you can afford to pare the monthly premium; and a policy from a financially stable company since a number of carriers have shuttered in recent years. Buy this book from Amazon.com.
- The Complete Idiot's Guide to Buying Insurance and Annuities by Brian H. Breuel (Alpha Books, 1996). Bruel, an attorney with 30-plus years experience in the insurance industry, understands this topic well and devotes a chapter to individual disability policies and another to business disability insurance. Breuel is good at addressing features you want and sometimes may have a tough time securing, as well as some features you may not want. Example: Many insurers have experienced heavy claims in recent years due to a policy feature that's very appealing to the insured but expensive for the insurers to offer. It's the ability of the insured to renew yearly at the same guaranteed premium if they have a noncancelable policy. As a result, Breuel writes that this feature has become more difficult—and more expensive—to find and buy. He also suggests opting for own-occupation coverage until age 65, if you can afford it since it defines your disability as an inability to perform the major duties of your occupation, not just any job. If you can't afford that feature, consider a policy that gives you as many years as you can pay for, he writes. Breuel also covers business disability insurance, which is useful for brokers who need insurance to pay their business bills to keep them afloat if they become seriously ill or have a major accident. To buy it, you'll have to itemize your business overhead expenses (BOE), such as rent, employee wages, taxes, utilities, insurance premiums, supplies, subscriptions, and professional fees. The book also has an excellent glossary. Buy this book from Amazon.com.
- Personal Finance for Dummies by Eric Tyson (John Wiley & Sons, 2003). Formerly a financial planner and now a full-time author, Tyson is, like many real estate practitioners, an entrepreneur dependent on himself for his income. In a chapter titled, "Protecting What You've Got," he describes the importance of disability insurance. He writes, "Being without disability insurance is a risky proposition, especially if, like most working people, you need your employment income to live on." His biggest selling point is that people under age 45 suffer more than a third of all disabilities, and most of these disabilities could not have been predicted. He also adds an acronym to our expanding vocabulary: COLAs, or cost-of-living adjustments, which, when included in a policy, automatically increase your benefit payment by a set percentage or according to changes in the inflation rate. One good caveat: If you purchase disability insurance through a local agent, be careful. Some may try to load your policy with so many extra bells and whistles that it'll pump up your premium, and up their commission, too, he writes. Tyson also offers two reasons you may not need this insurance: if your spouse earns a large enough income so you can do without yours or if you've accumulated enough savings for your future years without working. Buy this book from Amazon.com.
At the end of the day, the biggest incentive to buy disability insurance may be many experts' belief that not doing so is equivalent to a "living death" because you'll be unable to cover many essential expenses if you are unable to work for an extended period of time.


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The partnership with Servier
In 2016, we announced an exclusive research, option and license agreement with Baxalta Incorporated and Baxalta GmbH, which subsequently became subsidiaries of Shire PLC, whose oncology business was acquired by Servier in 2018. Under the agreement Symphogen has granted Servier an option to obtain, upon the achievement of certain development milestones, an exclusive, worldwide license under our technology to develop, make, and commercialize antibody therapies directed at certain agreed oncology targets and pharmaceutical products containing those antibodies.
Under the agreement, total payment to date amount to DKK 1.2 billion (upfront payment in 2016). The aggregated potential payments under the Servier agreement is estimated at DKK 9 billion plus royalties on worldwide sales.
By June 2018, three clinical trials had been initiated under the Servier agreement:
- A Phase 1 trial with Sym021, a mAb discovered by us that binds PD1 and blocks binding of the inhibitory ligands PD-L1 and PD-L2, thus releasing PD1-mediated inhibition of the immune response.
- A Phase 1 trial with Sym022, a mAb discovered by us that binds LAG3 and blocks the interaction with MHCII, thus allowing for increased T cell proliferation and cytokine production.
- A Phase 1 trial with Sym023, a mAb discovered by us that binds TIM3 and induces activation of immune cells.
The primary purpose of these trials is to determine if Sym021, Sym022 and Sym023 are safe and tolerable for patients with locally advanced/ unresectable or metastatic solid tumor malignancies or lymphomas that are refractory to available therapy or for which no standard therapy is available.
Collaboration and license agreement with Genentech
As a validation of our ability to apply the mAb technology to disease areas outside of cancer, we entered in 2008 into a collaboration and license agreement with Genentech Inc., a member of the Roche Group, for the identification of antibody therapeutics against undisclosed infectious disease targets. Under the terms of the agreement, Genentech made an upfront payment to us as well as an equity investment in Symphogen. We are eligible for milestone payments of around DKK 700 million (USD >100 million) upon the successful achievement of certain research and development milestones, as well as single-digit royalties on worldwide sales.
Under the terms of the collaboration, Genentech is now sponsoring the development of Sym009 for the treatment of certain methicillin-resistant or methicillin-sensitive strains of staphylococcus aureus (MRSA). Sym009 is currently in a Phase 1b clinical trial. The trial evaluates DSTA4637S, an investigational medicine containing Sym009 conjugated to an antibiotic agent, for the potential treatment of Staphylococcus aureus (S.aureus) infections. Sym009 was originally discovered by isolating antibodies from individuals exposed to S.aureus using Symphogen's patented Symplex technology.


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Saka had been popular as a model with Etisalat, especially with the series of adverts he did for them. So, it was surprising for the people to see the actor-cum-lecturer pitching his tent with another network.
His comic delivery of the adverts campaigns for Etisala had endeared him into the hearts of the people with his unique way of delivering his messages on television screen and radio. Saka, who happens to be one of the best comic actors in Nollywood, has won many awards in recent years.
A leading mobile service network, MTN engaged Saka through its agency, DDB to promote the new Mobile Number Portability (MNP) system recently launched by the NCC.
MTN employed the services of Saka to achieve its campaign of attracting customers, a move that has been described as a coup for Etisalat, which had been using Saka as its brand ambassador for about two years.
When contacted Saka on the development, Saka declined to speak on the 'controversial' deal with MTN.
"I just want to get your view about your recent deal with MTN, we learnt that you left Etisalat because MTN offered you a fairer deal, please confirm or deny sir," Our source asked Saka. "My brother (laughs), please, I don't want to talk on the issue for now," Saka responded.
When asked if he is happy about the new development, Saka said, "my brother, you just want to make me talk (laughs again), no comment."
Meanwhile, our source reliably gathered that MTN parted with about N20 million to woo Saka to its side. A source in the know said this was far from what Saka was getting from Etisalat as brand ambassador for the network for two years.
"Saka wasn't really a brand ambassador for Etisalat, he was only paid for any advert he did for them. Most of the time, he got a one-off pay for an advert campaign. He wasn't contracted as a brand ambassador for the network, unlike the deal he reportedly signed for MTN, which is worth N20 million," the source divulged to our source last week.


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Dust Collection Systems
Team Mixing Technologies manufactures a complete line of Pulse Jet and Shaker style dust collectors and baghouses to suit any requirement. Dust Collectors can be supplied to suit nearly any size requirement, as well as custom designed to suit difficult installations. TMT can also manufacture support structures, access ladders, ducting, inlet hoods, and all controls required for a turnkey dust collection installation.
- Standard Sizes 700 to 10,000 CFM (at 2:1 air to cloth ratio).
- Collectors can be manufactured to suit any requirement.
- Collectors can be integrated into hoppers, and other vessels.
- Filter media options, and temperatures up to 500° F.
- Custom inlet and outlet locations and orientations.
- High airflow capacity at low operating cost.
- Filtration efficiency of up to 99.9%
- Low inlet to outlet pressure drop.
- Supplied with NEMA 4 timer and Solenoid panel if required.
- Easy access for cartridge replacement, no tools required.


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Dennis Viollet... A United Man.
A film by Rachel Viollet
July 18, 2016 By Dennis Viollet Leave a Comment
Jacksonville Premiere
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We believe that all companies have
a fundamental duty to contribute to society
Organizing "Eco Cleaners" cleanup activities
"Everyone involved in fashion should do their bit to prevent polluting the earth." We call on our employees and affiliated companies to take part in volunteer cleanup activities that we organize twice a year. We carry out cleanup activities on a regular basis, in locations throughout Okayama prefecture and in the vicinity of our Tokyo HQ. Over 2,700 people take part in cleanup activities, wearing original vests.
Organizing "Cool Okayama Fes" to promote
everything Okayama has to offer
We organize "Cool Okayama Fes" as a project aimed at revitalizing the local community in Okayama. For example, previous events have included "Premium Food" and "Premium Marche," which involved some of Okayama's leading restaurants setting up stalls and selling local food products in the village of Shinjo. Connecting local people with leading restaurants helped to breathe new life into the local economy.
Fair supply chain initiatives aimed at creating clothes
that make everyone happy, whether making or wearing them
There are a great many companies and individuals involved in the process of making products and getting them to the customer. As well as the environmental and economic impact, there are also serious social issues to consider, including child labor, harsh working conditions, and environmental contamination from industrial waste generated from factories. To produce genuinely good quality products, we believe that we must confront social issues such as these and create better working environments. That is precisely what we are working to achieve.
Providing support for young athletes, to instill a challenging
spirit and enable them to take on the world
We have started to provide support for young athletes who are keen to compete on the global stage, in an effort to breathe new life into domestic sport ahead of the Tokyo Olympics and Paralympics in 2020. To date, we have signed sponsorship deals with international figure skater Takahito Mura and with tennis players from Okayama prefecture (Issei Okamura and Kyoka Okamura). Both of these tennis players also work with our global brand KOE as employees, and serve as sports wear advisors. Disabled swimmer Remi Watanabe meanwhile is working towards securing a place at the Paralympics while working in our Personnel Division.
Environmental initiatives based on tree-planting activities,
bringing greenery to arid regions of China
We have been carrying out tree-planting activities as part of the "one tree project" in the Horqin Desert in the Inner Mongolia Autonomous Region of China since 2009. As a consumer country that reaps the benefits, we believe that we bear some of the responsibility for desertification, caused by excessive farming and grazing. That is why we continue to engage in tree-planting activities, so that we can restore lush areas of forestland. We have already reached our target of planting 80,000 trees at "Earth Forest," and intend to focus on management in the future, to create a fully-fledged forest. Our Chinese subsidiary, launched in 2014, will also be continuing with activities aimed at restoring greenery.
Ongoing projects to help with disaster recovery
We raised money across 37 stores in the Chugoku region and 43 in the Tohoku region in support of the recovery process following the landslides that hit Hiroshima prefecture on August 20, 2014. Combined with donations from our customers, we raised a total of ¥3 million, which we then donated to help set up facilities for activities carried out by local students and a website to provide relief information. We had previously organized the Clover Project in support of those affected by the Great East Japan Earthquake. As a company that is active within society, we will continue to provide support for those stricken by disaster in the future too.
Regional revitalization initiatives in conjunction
with the Ishikawa Foundation
The Ishikawa Foundation organizes projects aimed at enhancing and promoting culture and the arts, and at helping to create and develop a rich local culture, primarily in Okayama prefecture. We provide support for a range of initiatives, including the "Okayama Award" scheme, which was created to give a boost to the economy and culture of Okayama prefecture, and to help entrepreneurs looking to revitalize the region. We also support arts festivals, with the aim of increasing interaction between different generations and nationalities, and nurturing greater sensitivity amongst future generations of children by bringing them into contact with art at an international level.


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Here, you'll find London Paddington Station. This large transport hub is the place where Paddington Bear first arrived in the capital after a long journey from deepest, darkest Peru. You can even pay him a visit – there's a statue dedicated to the loveable bear in the centre of the station. The train station also operates the Heathrow Express towards London Heathrow Airport, with services running several times an hour.
The key sights of Hyde Park, Kensington Palace and Marble Arch are all within walking distance; while sports fans will not want to miss nearby Lord's Cricket Ground – affectionately referred to as the home of cricket. Hotels in Paddington London also ensure easy access to the rest of the capital, with Regent's Park and Oxford Circus just a few stops away on the Bakerloo line from Paddington Underground Station.
Our favourite hotels
7.8/10 Average score from 153 reviews on
Access Paddington
These apartments are available with two, three and four bedrooms, making them ideal for group accommodation in Paddington, London. Each one has a fitted kitchen and a modern living area, including a flat-screen TV with Freeview channels.
8.3/10 Average score from 1286 reviews on
Bringing a Latvian taste to the capital, this Paddington hotel offers a selection of Latvian beers and traditional food on Fridays, with cheerful decor and free Wi-Fi.FromReserve
7.8/10 Average score from 618 reviews on
Columbus Hotel
Situated on an attractive tree-lined avenue, guests at this Paddington hotel can enjoy a continental breakfast. Each bed also has a high-quality mattress for added comfort.FromReserve
8/10 Average score from 4245 reviews on
Norfolk Towers Paddington
Each modern room offers comfortable bedding for a great night's sleep, with smart granite bathrooms. The central location also means Paddington Station is only a two-minute walk away from this Paddington hotel in London.FromReserve
8.5/10 Average score from 1473 reviews on
Park Grand London Lancaster Gate
With easy access to Heathrow Airport via nearby Paddington Station, this 4-star hotel offers convenience and the chance to indulge in afternoon tea at the on-site restaurant.FromReserve
8.2/10 Average score from 1555 reviews on
Arbor Hyde Park
This restored 19th-century townhouse has retained many of its period features, with traditional sash windows and views of neighbouring Hyde Park. Each room comes with an espresso coffee maker, bathrobes and slippers.FromReserve
7.4/10 Average score from 7363 reviews on
Hilton London Metropole
Hilton London Metropole is less than 10 minutes' walk from Paddington Station and 70 metres from Edgware Road Tube Station. This London hotel in Paddington features a restaurant, bar and a health club with an indoor pool.FromReserve
8.4/10 Average score from 1008 reviews on
Novotel London Paddington
One of the most convenient hotels in London Paddington, the Novotel is less than 200 metres from Paddington Station, and a five-minute walk from Regent's Canal and the Little Venice district. The hotel features an indoor pool, gym and on-site restaurant.FromReserve
8.1/10 Average score from 2422 reviews on
Hilton London Paddington
The hotel in London Paddington offers easy access to Paddington Station and its 15-minute rail connection to Heathrow Airport. The Hilton is home to a restaurant, gym and boasts rooms finished with Art Deco-style design.FromReserve


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Hooray for the Norwegian sketch-site Skissedilla, which recently celebrated 100 weeks (&sketches). Well, not really 100 sketches, but rather 99, as they decided to scrap older sketches for their 100th week :p
Congratulations, Skissedilla! I figured I had to join this one, and found this wonderful sketch by Carrin:
I'm not quite sure which number it is, but the filename says 12.. :p
Once again I grabbed old stuff I had lying (hoarding is bad, folks! ;p) around – mostly Sassafras (the patterned papers – plus one strip of Pink Paislee that was lying on the table), Love, Elsie (look! the epoxy-sticker! love these, having a hard time actually using them though – need to get better at this!) and rub-ons from Hambly Screenprints.
Plus – this calendar-tag from Elle's Studio – I've not used it because in my mind I thought it said 2011 on it, and I was like, gotta save it then! But for this project I thought – oh heck – let's use it and just cover up the 11 part of 2011 w/the photo – when I noticed it did say 2010 after all. Cough. Plus! See the starburst-punch? Lovesit. It punches through cardboard and – wait for it – transparencies as well! Like cutting through butter – gotta love it :) I think I have an idea what to do w/the punch next :) Just need some time to scrap – it's been sacred lately w/so much going on around here :(
I also found another sketch I think will be perfect for a card, I'll see if I can find some time to scrap tomorrow…
listening: Nightwish (LOVE "Bye Bye Beautiful")
eating: nothing yet…have chocolate-rolls & Oreo-muffins on the way, though!
drinking: 3 cups of coffee so far….
wearing: same as yesterday, will change for tonight though
feeling: antsy..
weather: Grey, rainy & somewhat windy..
wanting: to scrap…but….work calls..this time, on my thesis :p
needing: hairproducts for straight, no-frizzy hair
thinking: that I'll pay the local hairdressers a visit hunting for hairproducts soon..support your local businesses & all :p
enjoying: the music
wondering: how tonight will be – taking approx 8 boys (and a little girl) to go bowling..
Anna Said,
WOW your blog is looking good. I have been reading it for a while now through Google reader and hadn't seen the changes you have done over here. You are one of my fav visits. Keep it up you are great !
Thank you :)
ParentesFantomet Said,
Gubban så kul!
Jeg digger og PostSecret, likte spesielt godt den med vedkommende som stammer, gir håp for verden. *klem*
PostSecret er en av ukens faste höjdare :)
pattyo Said,
Love how the scallops make the layout pop. Thanks for the tip on scalloping a brad. Streaks put in the hair here are called highlights.
Gotcha! Thanks :) And thanks for the tip on poems.com :)
pattyo Said,
Oh, forgot--post a photo of your new 'do.
Mari Said,
hello, show us the new haircut!!! You can't tell about it two times in a row, without showing!:)
Riiiight…um..alright, you asked for it…iPhone-images incoming from the whole process :p
Haircut done, coloring+highlights next..
Amalie also got her hair cut..
Love her hair when short (easier for us and her, see her amazing bedhair-photo here :p) + I think she looks like Amelie (from the French movie)/a cute pixie w/short hair :)
Me again…w/ponytails like them Asian girls on gomtv.net haha..*cough*
Have a nice weekend :)


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The Development
The Grünenthal Group founded in 1946 is an independent, family-owned international research based pharmaceutical company headquartered in Aachen, Germany. In 1947 Grünenthal was the first West German company to produce and distribute penicillin. Years later, 1977, Tramal®, the world's most prescribed pain medication with central effect and only one active ingredient, appeared on the market. Since 1979 the Grünenthal Group has grown to have affiliates in 26 countries worldwide. Grünenthal products are sold in more than 155 countries and approx. 4,500 employees are working for the Grünenthal Group worldwide.
In 2000, Grunenthal opened its US affiliate, Grunenthal USA in New Jersey. In that same year, Zaldiar®and Transtec® were launched globally. In 2001, Grünenthal developed and introduced the first patch for pain in Europe. Since 2004, Grünenthal has made considerable investments in R&D and late clinical trials. Tapentadol was approved in the US in 2008 and marketed in 2009 with the launch of Nucynta® with Johnson & Johnson.
Building on its unique position in pain, Grünenthal's objective is to become the most patient-centric company and leader in therapy innovation. Grünenthal is always searching for innovative ways to treat pain better, more sustainably and with fewer side effects. Our research and development strategy concentrates on select fields of therapy and state-of-the-art technologies. We constantly are searching for new ways to treat pain better, more effectively, and with fewer side-effects than before.
In 2011, Grünenthal re-marketed its' proprietary TRF (Tamper Resistant Formulation) technology under the brand INTAC®. INTAC® is a novel tablet form which restricts manipulation due to its high mechanical stability and poor solubility and thus impedes drug abuse.
|Palexia® available in UK, Spain, Italy, Denmark, Sweden, Switzerland and Ireland; FDA approval of Tapentadol ER (August) for chronic pain.
|Marketing authorization of Tapentadol IR and PR in 26 EU countries
|EU submission of Tapentadol for acute and chronic pain, launch of Nucynta® in the US by Johnson & Johnson
|Approval of Tapentadol in the US
|Since 2004
|Broad investments in R&D and late clinical trials
|Since 2000
|Global launches (Zaldiar®, Transtec®)
|Since 1990
|Increasing internationalization of Grünenthal through local founding of subsidiaries and acquisitions
|Expansion of the Latin America business through founding of subsidiaries in Columbia and Chile
|Tramal® launched – worldwide partnering
|First international activities
|Registration of Penicillin
|Hermann Wirtz founded Chemie Grünenthal GmbH


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THE Muslim Jewish Forum of Greater Manchester won the award in the category Spirit of Britain at the Islamic Bank of Britain British Muslim Awards last night.
At a packed awards dinner ceremony, attended by more than 300 people, Cllr Afzal Khan CBE, the co-founder of the forum and Heather Fletcher, the company secretary accepted the award on behalf of the forum.
They dedicated the award to the forum's late co-founder Henry Guterman MBE. Henry was a refugee from Nazi Germany who came to the UK aged 12 and spent all of his life fighting racism and was also an interfaith activist.
Heather Fletcher said: "I am so delighted that we have won this award and received national recognition. I hope this win raises our profile and that more and more people join us and spread our positive message that Muslim people and Jewish people can work together and learn from each other."
Cllr Khan said: "When we started our forum 10 years ago, never in my wildest dreams did I think we would get national recognition. I would like to thank all of the people who have been engaged in taking our forum forward.
"There is a need for all of us to try and unite in our global village. It is important that we reach out to one another."


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Mortgages are getting old, a sign that some families are still struggling to get a new loan, while others have already refinanced and are enjoying their cheap monthly payments, according to a report released Monday.
The average mortgage age hit a record-high of 54-plus months in August, up from an average of about 50 months in the year-earlier period, according to Black Knight Financial Services, a mortgage technology and information services firm based in Jacksonville, Fla. That age statistic shows how long a borrower has a loan before paying it off, typically through a home sale or refinancing, or before the loan was closed due to a foreclosure.
"The more newer loans you have, the lower the loan age," said Kostya Gradushy, Black Knight's research and analytics manager.
Part of the increase in loan age can be traced back to the plunge in refinancing seen since mortgage rates started rising. Borrowers who nabbed ultra-low mortgage rates have no interest in refinancing now that loans are pricier.
The more troubling portion of rising loan age is the chunk that's due to borrowers with credit and financial problems who can't get a new loan, whether it's to buy a home or refinance. About one-in-10 mortgaged U.S. properties were underwater in the second quarter -- owners owed more on a mortgage than a property was worth -- so they are both struggling with current payments and will have trouble getting a new loan.
"The equity on their homes is not at the point that selling their house would be reasonable," Gradushy said.
As seen in the chart, the average loan duration for those with lower credit scores is relatively high -- the lower the score, the higher the average mortgage age.
Average mortgage age could decline as home purchasing, rather than refinancing, drives the mortgage market and credit conditions loosen from the strict standards erected in the wake the meltdown, said Ken Fears, an economist with the National Association of Realtors. Officials and lenders may start to pare back some mortgage fees, he said.
"If we see a net decline in the cost [of loans] to consumers, we could see a lot more volume," Fears said.
There's a silver lining to aging home loans: There's a smaller prepayment risk for investors in mortgage-backed securities. That is, if fewer borrowers pay back their loans early, that should protect MBS investors from the financial hit of losing expected interest payments.
"The longer the [average loan age] is that means the longer they will be receiving payments and interest on these loans," Black Knight's Gradushy said.
--Ruth Mantell
Follow Ruth on Twitter @RuthMantell
Follow the Capitol Report blog on Twitter @CapitolReport
Check out these Capitol Report links:
Americans' opinions of Boehner and Reid worsen
One thing missing from good jobs report: Higher wages


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Friday, May 15, 2009
Gift in a Can
I wrote an Instructable for a Gift in a Can, featuring a pull-top can that was the former home of fire roasted tomatoes. It's a really simple concept but I thought I'd do a photo-filled tutorial for it. Just for fun, I canned my youngest daughter's chenille Easter chicks and then we released them into the wilds of her bedroom.
Posted by Craftastic at 11:37 AM
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What ONE thing can you do for the fair?
Help as little or as much as you like.
Here's where we need volunteers so far, watch for more tasks to be added as the date grows near.
Set-up Help
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Wipe tables in the community center. No need to stand around and wait for dirty tables, just swing in every so often and give open tables a wipe. on August 18, 2018
End Time: 4:00 pm
If you have an account, it is strongly recommended that you login before you sign up so that you can view and edit all your signups.
Bingo Help
Event Help
Clean Up Help
Hang Button Clues
We're also looking for help writing clues. If you have a good grasp of the city and history of Meadowlands, send us an email: firstname.lastname@example.com


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Contact Us
Mailing Address
Behavioral Health Associates
6216 Airpark Drive
Chattanooga, TN 37421
Telephone & Fax Numbers
Phone: (423) 899-0024
Fax: (423) 899-5688
Attention New Patients!
You may now contact us by email to schedule your initial appointment. Note, this email is ONLY for new patients and is not to be used in an emergency. If you have an emergency, please call 911 or go to your closest emergency room. Exisiting patients need to contact the front desk at 423-899-0024. For new patients only, please complete the following form and email it to firstname.lastname@example.com or fax to Attn: Ashley, fax: 423-899-5688. Thank you!
New Communication Method via Microsoft HealthVault
In the US, the Direct Project allows healthcare organizations, doctors, and patients to send authenticated, encrypted health information directly to recipients over the Internet. The health message service in HealthVault uses "Direct," a protocol designed specifically to communicate with health care providers. For that reason, health messages can only be sent and received with providers that use a system that's set up to do that.
When you give an organization the Direct address for your HealthVault record, they can send health information to your HealthVault record directly. Health messages received are automatically added to the HealthVault record, and an email is sent to each custodian's contact email address to notify them that a message has been received in HealthVault. Attachments are automatically added to the record, unless a custodian changes the record's settings to require that attachments be manually added.
To register, please visit the Microsoft HealthVault and log in with your Microsoft account. You may find more information about this program in their Help section.


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Doraemon Toy Machine is an excellent toys physics-puzzle game that allows you to remember your childhood of hunting for toys. In every level you must get one target toy, you have 3 attempts to grab the toy. Enjoy the toy machine game with your favorite Doraemon character!
Use mouse or space bar to play game.
How To Play Flash Games
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