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Email information is followed by @css.edu unless otherwise noted.
Sheryl Scheer Sandahl, DNP, RN, FNP-BC, MPH, MSN
Baccalaureate degree in nursing from St. Olaf College. Certified Pediatric Nurse Practitioner from St. Catherine's University with a Master of Public Health degree (Maternal Child focus) from the University of Minnesota - Twin Cities. Master of Science in Nursing and a Doctor of Nursing Practice from Case Western Reserve University Frances Payne Bolton School of Nursing. Post-Masters Family Nurse Practitioner Certificate from The College of St. Scholastica. Joined the CSS community full-time in 2002. Teaching experience in online, classroom, skills lab and simulation, and clinical environments in undergraduate and graduate nursing. Interests include curriculum development and assessment, simulation, and collaborative testing in nursing education. National League for Nursing Simulation Institute Leadership participant for 2018. Experienced Commission on Collegiate Nursing Education site evaluator. Grant reviewer for U.S. Department of Health and Human Services Health Resources and Services Administration. Member of Sigma (National Honor Society for Nursing), National League for Nursing and the American Academy of Nurse Practitioners.
Carrie Alajoki has focused much of her nursing career focusing on high quality care in the rural setting. Her MSN specialized in nursing education and her teaching interests include the adult learning and creative teaching strategies such as the online learning environment. Carrie Alajoki's nursing experience includes medical/surgical, emergency nursing, obstetrics - including labor and delivery, newborn care, and postpartum care - and occupational health and wellness nursing.
Recent Achievements:
Carrie Alajoki prepared a poster presentation for the Scholarship of Teaching and Learning conference in Savanah Georgia that focused on "Adding a Faculty-Led Online Interactive Meeting in an Hybrid Nursing Course.
Palm Beach State College- Associates of Science in Nursing (ASN)- 1994
Liberty University- Bachelors of Science in Nursing (BSN)- 2013
Liberty University- Masters of Science in Nursing (MSN)- 2016
Biography: Assistant Professor Bisila has over 20 years of nursing experience dedicating her career primarily to geriatric and Hospice nursing. For the past four years she has taught at two different institutions, preparing healthcare workers for medical practice. She has taught nursing assistants, practical nursing and post baccalaureate nursing.
Recent Achievements: Laurie Bisila is a member of Sigma Theta Tau, National Nurses Association, Nurses Christian Fellowship and Hospice and Palliative Nurse Association. Additionally, she is certified as a Healing Touch Practitioner and as a Public Health Nurse.
Cynthia Brown's clinical focus is in public health, nutrition, and substance use disorders. Her professional interests include community/public health, working with underserved & vulnerable populations, service-learning, chemical dependency/addiction, and the harm reduction model. She is also involved in various service-learning initiatives in local and global settings.
Bushey, Teresita "Tessie" MA, RN
Position: Asst. Professor, Nursing
Department/School: School of Nursing
Phone: (218) 723-6771
Email: email@example.com
My area of specialty lies in the practice of nursing in rural areas. I have worked in arctic Alaska, critical access hospitals, and home health/hospice in remote areas. As healthcare delivery changes, and the role of nursing shifts away from acute care and into chronic disease management and health promotion, rural nurses will be invaluable links to provide quality care.
My teaching experiences begin in rural Alaska with some of the first distance delivery methods in place. It was quite interesting to teach American Heart Association CPR to Inupiat Eskimo first responders who truly understood how far away you might be from an acute care hospital setting. Currently I teach Professional Nursing courses for the undergraduate nursing program helping students see the complex relationships between healthcare policy, cost of care delivery, and the unique role of each staff nurse as a leader. All nurses are leaders. My most recent passion has been to develop Interprofessional healthcare teaching teams to allow students to leave their silo style education and develop collaborative care plans.
As a leader within the Traditional Track in the Undergraduate Nursing Program I seek to inspire our faculty team to find the best way to educate the nurses of the future, teaching students to blend skills in technology with compassionate, holistic, quality care. We seek to create nurses who are strong patient advocates, nurses who use the Benedictine values as part of their anchor for moral decision making, and finally nurses who are able to seek answers rooted in Evidence Based Practice. As healthcare becomes increasingly complex, the nurses of the future are called to imagine new delivery care models. Imagination and problem solving can be stimulated by accessing a liberal arts foundation.
My outside interests include experimentation in a broad range of textile arts, extensive travel abroad, and the production and cooking of local foods.
University of South Alabama, Master of Science in Nursing, 2011
Auburn University Montgomery, Bachelor of Science in Nursing, 2006
Park University, Bachelor of Science in Social Psychology, 2004
Professional Licensure:
Jody Cadotte began teaching full-time in the RN to BS Nursing Program in the fall of 2016, after teaching as an adjunct faculty member for the program. Jody holds a Bachelor of Science degree in Social Psychology from Park University and a Bachelor of Science degree in Nursing from Auburn University. In 2011, she earned her Master of Science degree in Nursing from the University of South Alabama with a Women's Health Nurse Practitioner specialty. Her professional nursing experience includes neonatal intensive care nursing, maternal child health nursing, plastic surgery and women's health. Jody is passionate about nursing and nursing education, especially online education. Having obtained 2 degrees online herself, she has a solid understanding of the unique needs of the distance learner, and understands the importance of creating an inclusive learning environment for all students. Jody has a love of teaching, and a strong commitment to nursing. She understands the importance of providing all nurses with a strong educational foundation. Jody is honored for the opportunity to educate and mentor future generations of nurses, and to be part of the amazing community at The College of St. Scholastica.
I manage the clinicals for nursing students in the undergraduate and post-baccauluareate programs. I place students in clinical sites and troubleshoot issues; I interface with the clinical facilities; and I hire and provide basic orientation of adjunct faculty. I also oversee the program-wide testing that is done. As a trained philosopher I teach occasionally in the philosophy department.
Emily Davis, MS, APRN, CNM is an Assistant Professor in the traditional undergraduate nursing department. She joined the faculty team in 2018. She holds an M.S. in nurse-midwifery from Bethel University, B.S. in nursing from The College of St. Scholastica, and a B.A.S. in psychology from the University of Minnesota, Duluth.
Her interests in nursing are focused in maternal-child health with experience delivering care in both the hospital and birth center settings, as well as within the community as a public health nurse. Working as a prenatal educator is what initially sparked her interest to pursue nursing education and she is excited to be at the college focusing primarily in maternal-child health related content areas.
The College of Saint Scholastica- Doctor of Nursing Practice in Advanced Practice Nursing, 2015
The College of Saint Scholastica- Gerontology Nurse Practitioner Certificate, 2011
The College of Saint Scholastica- Master of Arts in Nursing (Adult Nurse Practitioner Track), 2007
Philippine Christian University-Mary Johnston College of Nursing- Bachelor of Science in Nursing, 1982
Dr. Diaz is an Associate Professor in the School of Nursing, College of St. Scholastica Duluth campus. She teaches full time in the Traditional Undergraduate Nursing Program, teaching core courses, clinical, and skills lab and simulation. Dr. Diaz came to St. Scholastica in 2004 as an adjunct clinical faculty and joined as a full-time faculty in 2007. Her clinical background includes critical care nursing and geriatric nursing. She integrated geriatric content into the Traditional Undergraduate Nursing Program at The College of St. Scholastica for her doctoral project. She developed an international capstone (Philippines Capstone) experience for senior level nursing students.
Dr. Diaz is a recipient of the Max H. Lavine Award for Teaching Excellence 2017 from The College of St. Scholastica. Her teaching philosophy is to create and provide a welcoming and positive learning environment that enhances knowledge, skills, and attitude; allows and encourages students to engage in civil and respectful discourse; and offers a sense of belonging regardless of cultural background and intellectual abilities.
Senior Level Core Courses
Gerontology Clinical Specialty
International Capstone Experience
Recent Scholarly Activity:
Diaz, G. B., Byrne, P., Imperial, E. (2017). Prelicensure international immersion illuminates shared professional values and discovery of nursing voice in cultural humility. Poster Presentation at the 28th International Nursing Research Congress, Sigma Theta Tau International Honor Society of Nursing, Dublin, Ireland.
Upon graduating from St. Scholastica with a baccalaureate degree I found myself launched into a variety of wonderful practice experiences. My early nursing career was focused primarily in the care of the obstetrical and newborn client, as well as with the acutely ill hospitalized adult client, particularly those with cancer. But the pull back to St. Scholastica and to education in particular became very strong in time, and I decided to pursue a graduate degree as a Clinical Nurse Specialist in Adult Nursing. This preparation afforded me the incredible opportunity to begin a career that focused on the education of nursing students. As a faculty-member in the Traditional Undergraduate Program, School of Nursing, I am privileged to work with students in a variety of venues; classroom, skills lab, simulation lab and the clinical environment.
My philosophy of teaching is to serve as an "experience facilitator" for the students I work with. Learning experiences occur in the most unexpected and unpredictable ways if one is receptive and curious. I have quickly come to realize that health care changes much too fast to prepare students for all that they are likely to encounter. If, however, I can teach students to be an effective lifelong learner, I have succeeded in teaching.
Professional Affiliations:
Dr. Nancy L. Falk is a nursing leader, educator, and scholar with a collaborative style and interdisciplinary perspective informed by clinical, informatics, policy, and business/leadership understanding and experience.
She has been a substantive contributor in non-profit organizations, government agencies, academic institutions, private entrepreneurial ventures, publicly traded corporations, and her family's manufacturing and retail business. Her primary area of expertise is in aging worker/workforce issues.
Dr. Falk was a trailblazer (1980s-1990s) in biomedical informatics leading clinicians and researchers to embrace electronic research tools and emerging technology solutions to enhance clinical practice and research. She was instrumental in initiating and developing the Nurse Faculty Education Act of 2005, as the John Heinz U.S. Senate Fellow in Aging Policy.
As a founding faculty member of the School of Nursing at the George Washington University (2009-2016), she served as co-director on a Robert Wood Johnson (RWJ) Funded Nursing Alliance for Quality Care grant and as co-PI on an Agency for Healthcare Research and Quality (AHRQ) grant focused on Nurses' Contributions to Fostering Successful Patient Engagement.
Teaching: A passionate educator and lifelong learner, Dr. Falk focuses on empowering current and future nursing leaders - helping them to be effective, influential, and impactful in clinical, educational, policy, research, and other roles. She promotes learning by doing and engages students in real projects to help them gain skills and confidence so they meet and exceed professional goals. Recent Teaching Honor: Sigma Theta Tau, Epsilon Zeta Chapter, Excellence in Nursing Education Award (2015).
Service: Elected member of the National Academy of Social Insurance. Serve on Social Research, Policy and Practice Executive Committee of GSA as Mentoring Committee representative. Service Highlight: Fellow in Gerontological Society of America (GSA) (2016).
Falk, N.L., Rudner, N., Chapa, D. & Greene, J. Nurse practitioners and intent to retire. Journal of the American Association of Nurse Practitioners, October 2016.
Falk, N.L. Infographic development by Accelerated Bachelor of Science in Nursing (BSN) students: An innovative technology-based approach to public health education. Nursing Education Perspectives. September/October 2016, p. 299-301.
Education: University of New Mexico - MSN 2000 Suomi College - AD nursing 1995 Bradley University - BA International Studies and Political Science 1988 Biography: Mary moved to Duluth in the fall of 2017 with her husband and teenage daughter after living in Utah, NM, and Arizona since 1995. She has over 20 years of experience providing direct patient care in multiple different rural settings. Currently at St Scholastica she has taken on an administration role in the School of Nursing as a grant manager for the graduate nursing department, which is a new and exciting challenge.
My areas of interest are family nursing, underserved populations, climate change and trans-cultural nursing. These passions reveal themselves in the stories I share with students – from the cancer ridden illegal refugee seeking asylum in the US, to the woman with no pre-natal care who arrived in my clinic ready to give birth, to the homeless teen mom with a multiply handicapped baby. Engaging the affective domain through story telling helps breach the gap between academics and humanity - the very real needs of our patients within the larger context of family, community, political/economic realities and the globe. I have taken students to Belize twice to engage them in direct service learning projects in a transcultural setting and will be traveling there again in January 2018. I hope to expand these offerings to Alaska in Spring 2018.
When not teaching, I unwind by writing, spending time with friends, and being replenished by the presence of wind and sky over our Great Lake.
Assistant Professor, Graduate Nursing
Clinical Practice: Infectious Disease Associates, St. Luke's Hospital and Clinics, Duluth, MN
International Travel Clnic, St. Luke's Hospital, Duluth, MN
Areas of interest include: Preventive care/Immunizations, Hepatitis C, and HIV, and complex case management that includes outpatient antimicrobial therapy aa well as prior authorization of expensive treatments. I am also interested and support independent practice for APRN's, healthcare reform, and the promotion of nurses as scholars.
Julie Kantarik started teaching in the RN to BS Online Nursing Program in the Fall of 2014, bringing seven years of teaching experience to The College of St. Scholastica. She earned an AD in Nursing from Minneapolis Community College, a BA in Nursing from The College of St. Scholastica, and a MS with a major in Nursing from The College of St. Scholastica. Her professional experience as a nurse focused on cardiovascular and gerontological nursing with an interest in chronic disease management. She is passionate about fostering learning for students that decide to continue their education in nursing. She is excited to support The College of St. Scholastica in providing students "Direction for Life."
Dr. Kemnitz has baccalaureate degrees in Biology and Nursing from Carroll College and the University of WIsconsin Oshkosh respectively. He received his PhD in physiology from Marquette University, Milwaukee, WI in 1994 with a specialization in neurophysiology and completed a Masters of Nursing Education in 2015 at Western Governors University. Dr. Kemnitz has extensive collegiate teaching experience in biology and nursing and has been the recipient of several awards and honors including the Max Levine Award for Excellence in Scholarship, the Daisy Award for Teaching Excellence in Nursing, and is a Minnesota Hartford Geriatric Nursing Scholar and FLAG fellow. Nationally, Dr. Kemnitz is a recognized subject matter expert in anatomy & physiology and nursing and is a consultant for the American Council on Education. Dr. Kemnitz has published and presented many articles in basic science and educational practices. He continues to pursue his interests in geriatrics and nursing education. Most recently Dr. Kemnitz was selected as a Sigma Theta Tau International Rising Star for his masters thesis work on nursing student clinical evaluation.
St. Catherine University-Doctor of Nursing Practice, 2016
University of MN-Master of Science in Nursing, CNS track
The College of St. Catherine, St. Paul,- Bachelor of Science in Nursing
Dr. Knuths is currently serving as the interim Department Chair of Undergraduate Nursing Programs. Her clinical background includes critical care nursing, healthcare administration and healthcare research. Her research focus is evaluating student's clinical reasoning development in the simulation setting. Dr. Knuths incorporates active learning in her concept-based courses to engage students in their journey to professional nurse. Her teaching philosophy includes the conviction that students need to be supported with respect and compassion while challenged to reach higher and go farther. Dr. Knuths' Professional Nursing courses integrate scientific knowledge, leadership principles and ethical values to educate the next generation of professional nurses.
Medical-Surgical Clinical Education
Nursing Simulation Laboratory
Professional Nursing courses
The College of St. Scholastica - Bachelors of Arts in Nursing, 2003
The College of St. Scholastica - Doctor of Nursing Practice in Family Nurse Practitioner, 2016
St. Cloud Technical College – Practical Nursing Diploma, 2003
Ridgewater College – Registered Nursing ADN, 2005
Walden University – Walden University BSN, 2010
Walden University – Walden University MSN, 2012
Mary's MSN specialized in Nursing Education. Her teaching interests include simulation and teaching in an online learning environment. Mary's nursing experience is in medical/surgical areas. She worked in Orthopedics and Neuroscience units most of my nursing career. Mary continue to work at a Nursing home and a critical access hospital. Mary lives in a small rural area where she and her husband raise their two boys. Mary is active member of her community and school system.
· Health Transitions 1, 3, 4
· Nursing Labs for all course
Capstone Clinical.
When I started college, I was a business major. During my sophomore year, I switched to nursing and it was the best decision that I have ever made! As a graduate of the CSS nursing program, I can appreciate the history and reputation of the College. Nursing has proven to be a fulfilling career that has taken me in many professional directions. As a staff nurse on a post-coronary care unit for 10 years, I had the opportunity to care for patients, be a mentor/ preceptor and charge nurse. I went back to school and received my Master's degree and worked as an acute care nurse practitioner in cardiology and primary care. Now, I have the opportunity to share my knowledge and experience with students to help educate a workforce of future professional nurses.
My philosophy of teaching is that, as nurses, we get to care for individuals, with our hands and our hearts, at the most vulnerable times in their lives. It is a responsibility and privilege that should not be taken lightly. In order for students to feel confident and competent in caring for patients, we need to prepare them for real-life clinical situations. My primary responsibility is to coordinate and teach in the skills and simulation labs for the School of Nursing. Students participate in classes that allow them to practice not only the hands-on skills that they will use in the hospital setting but also to practice professional behaviors and therapeutic communication. We are able to combine technology, through use of high fidelity, interactive manikins, with the fundamentals of holistic, baccalaureate nursing practice as well as the Benedictine values to engage students in realistic, simulated patient-care experiences. Students progress through increasingly complex skills from sophomore year when they learn basic health assessment until the senior year when they learn to respond to life-threatening situations. Helping students to integrate nursing theory, critical thinking and technical skills has been my most rewarding career yet.
Dr. McRae graduated from The College of St. Scholastica in 2015 from the MSN program and became an Adult/Gerontological Nurse Practitioner with expertise in addiction medicine, older adults, and creative care delivery. Dr. McRae graduated from the CSS Post-Graduate DNP program in 2018 and enjoys teaching in the graduate nursing program. Dr. McRae teaches DNP core courses, APRN foundations, and DNP Clinical Project courses. He has also served as a clinical instructor for the post-baccalaureate undergraduate nursing program. Dr. McRae maintains a full-time hospital based clinical practice in addition to teaching at CSS.
Courses Taught
As an advisor for the Non Traditional Nursing Program, I am responsible for supporting online students from time of acceptance to the College through the time of graduation. I am the student's professional point of contact with the College and to assist students with all academic matters. I provide an orientation to all new students to ensure they have the information they need to be successful in the online program.
MSN- College of St. Scholastica 2010
BSN- College of St. Scholastica 2007
B.A. - Biochemistry/Biology- College of St. Scholastica 2004
EMT Certificate Mesabi Range Community and Technical College - 2012
Biography: Research interests include multimorbidity management, palliative care, population management, care of the older adult with dementia.
Courses: Advanced Pharmacology, Lifespan Health Assessment
The College of St. Scholastica - Doctor of Nursing Practice, 2017
The College of St. Scholastica - Family Psychiatric-Mental Health Nurse Practitioner Certificate, 2014
Walden University - Nursing Informatics Certificate, 2011
University of Phoenix - Master's of Science in Nursing & Master's of Business Administration, 2008
Psychiatric-Mental Health and Clinical Project Courses in the Graduate Nursing Department.
Amos Restad is an instructor in the traditional undergraduate nursing department. His primary content area is medical-surgical nursing theory, lab, and clinical. Prior to joining the faculty team in 2015, he worked as a registered nurse at Essentia Health in the adult critical care units. He maintains a position there on a casual status. He received his B.S. in nursing and his B.A. in biology from The College of St. Scholastica in 2010. In 2013 he attained his critical care certification through the American Association of Critical Care Nurses. He is currently enrolled in the doctorate of nursing practice program at The College of St. Scholastica and is pursuing his family nurse practitioner credentials.
Amos has worked with the faculty team to develop a concept-based nursing curriculum. He is a member of the International Nursing Association for Clinical and Simulation Learning (INACSL), and he has developed new simulations based on INACSL guidelines. Additional service activities include developing a guide for faculty recruiting incoming students and educating faculty and staff within the school of nursing on use of new technology that may enhance learning opportunities. In his spare time he enjoys spending time at the gym, gardening, kayaking, and motorcycling with his family.
Professional Nursing & Health Care II
Health Continuum II: Individual Physiologic Responses Theory
Health Continuum II: Individual Physiologic Responses Lab and Simulation
Interprofessional Care Coordination of Veterans
Medical-Surgical Clinical
Professional Nursing & Health Care V: Transition to Practice Theory
Professional Nursing & Health Care V: Transition to Practice Simulation
Doctorate of Nursing Practice
The College of St. Scholastica
Duluth, MN
Master of Science in Nursing
University of Minnesota
Minneapolis, MN
Bachelor of Science in Nursing
Bethel University
St. Paul, MN
Teaching Responsibilities:
Recipients of Care across the Lifespan II and III - theory and clinicals; Health Continuum II and III - clinicals; Health Continuum V - lab and Alaska Capstone.
Academic and Research Interests:
Pediatrics, Community Health Nursing including School Based Nursing, Food Allergy Awareness, and Evidenced Based Practice.
Hibbing Community College AA/ADN
The College of St Scholastica BSN, MSN, DNP student
Biography: Andrea Simek MSN, RN, FNP-C is an Assistant Professor in the Traditional Undergraduate Nursing Program. Interests include women's health, obstetric nursing, community nursing, including rural and underserved population health.
Recent Achievements:
Andrea Simek is currently enrolled as a DNP student at The College of St Scholastica. Andrea's research in the DNP program has combined her interest in rural health and faith based nursing. Andrea is currently studying the potential effects of a rural faith based health promotion program on cardiovascular risk. Anticipated graduation of DNP program spring semester 2017.
NSG 2222: Lifespan I Theory Professor: Growth and Development, Genetics, Functional Ability
NSG 3111: Professional Nursing II: Technology and Informatics, Interprofessional Communication, Evidence Based Practice
NSG 3334: HEC II Lab Instructor: Junior skills series
NSG 3337: HEC III Psychosocial Responses: Reproductive Health Theory and Lab
NSG 3222: Lifespan II Community Health Clinical Coordinator and Instructor
NSG 4222: Lifespan III Global and Community Health Theory Professor, Clinical Coordinator, and Clinical Instructor
NSG 4113: Complex Simulation: OB Nursing and Neonatal Nursing
NSG 4337: Alaska Capstone Travel Experience Coordinator and Clinical Faculty
Concordia College, Moorhead, MN - Bachelor of Arts in Nursing
Saint Xavier, Chicago, IL - Masters of Science in Nursing; program focus: Clinical Nurse Leader
Concordia University, Mequon, WI - Doctor of Nursing Practice; program focus: Executive Leadership
Assistant Professor Tollefson has enjoyed working in various areas of nursing. She began her career as a staff nurse in the Emergency Department in both rural and urban settings. Dr. Tollefson has been a travel nurse in California and rural ND. She has also worked in psychiatric/mental health, medical/surgical, long-term care, and ambulatory surgical settings. She has been in nursing education since 2010 and has recognized a love for developing the nursing workforce.
Areas of Focus:
Psychiatric/Mental Health
Veteran-Centered Care
Community/Public Health
Emergency Nursing
Education: Lake Superior College - Associate of Arts, 2009
Wisconsin Indianhead Technical College - Associate of Science in Nursing, 2011
Community College of the Air Force - Associate of Applied Science in Allied Health, 2012
Minnesota State University Moorhead - Bachelor of Science in Nursing, 2014
Simmons College - Master of Science in Family Nurse Practice, 2017
Greg is an advanced practice registered nurse and Veteran with experience in multiple roles including pre-hospital, flight and military medicine, emergency and critical care nursing, as well as nursing education and leadership. His current role at CSS is as the Veteran Faculty Lead and Clinical Liaison for the Veteran to BS in Nursing Program. He serves as the advisor and clinical instructor for cohorts of Veteran and service-connected nursing students throughout their entire academic progression in the Undergraduate Nursing Program. His goal is to help train Veterans to be excellent nurses who are able to continue to serve their community after their uniformed service to their country is complete through the acknowledgement and inclusion of their very unique experiences and skills into their nursing education.
Recent achievements:
He is an inductee and active member of Sigma Theta Tau International Honor Society of Nursing, and holds certification in Family Nurse Practice from the American Association of Nurse Practitioners (AANP), of which he is also a member.
NSG 3334: Health Continuum II (Clinical)
NSG 3222: Nursing Care Across the Lifespan II (Clinical)
NSG 3337: Health Continuum III (Clinical)
NSG 3370: Pathopharmacology for Nursing Practice (Lecture, Faculty Lead)
NSG 4222: Nursing Care Across the Lifespan III (Clinical)
NSG 8150: Pathophysiology for Advanced Clinical Practice


text: Hosted by China Computer Federation, organized by the College of Computer of NUDT, and sponsored by the National Natural Science Foundation of China, the first meeting of future computer was successfully held at NUDT, from 17th to 18th June. This was an international academic meeting on the frontier and future development of computer science, mainly with the world's Chinese scientists and foreign scholars focusing on the frontier and future development of computer science. Eight wonderful invited lectures were arranged, involving the future system research, the new generation of high performance computing, the continuous computing, the cloud services, and so on. Six thematic seminars on the high performance computing, the network computing, the intelligent computing, the dependable computing, the computer science education and cross-fields science research, the embedded system technology development and application, were organized, which offered a good academic communication flat to the computer scientists and young scholars.

subset: commoncrawl


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Create your own shabby chic furniture for a cool, funky look. Shabby chic furniture is extremely popular, but can be very expensive. It is easy and fun to paint and distress your own pieces. Poke around yard sales, vintage stores, or your own attic to see if you can find old pieces of furniture that would lend themselves well to this look. Just make sure the furniture is solid wood. Pieces that have a veneered surface will not give the same effect.
Step 1--Prepare the Surface
Make sure the surface you are going to work with is clean. Remove any drawers or other hardware and wash it with warm, soapy water. Allow it to dry thoroughly. If there are any rough places you don't like or wobbly legs, now is the time to fix them. Sand the surface until it's ready to accept the finish treatments.
Step 2--Rub on Wax
If you like the look of cracking or peeling paint, there's a way you can achieve it. Before you put on your paint, rub a wax candle here and there on your piece of furniture, wherever you want cracking or peeling. The paint will roll and peel where the wax has been applied.
Step 3--Paint
Most of the time, shabby chic furniture is covered in either a flat paint or satin paint, as high-gloss isn't the look most want to achieve. Put a good coat of this paint on your piece and allow it to dry.
If you want a two-tone look, paint one color on the first coat and let it dry. After that, apply more wax and then paint a different color for the second coat. The top coat will come off in places to give a worn look and show the under-color.
Step 4--Distress the Surface
After the paint is dry, whether you used the one- or two-coat method, it's time to get the aged or distressed look you desire.
This can be a lot of fun to do. Think about your piece and consider where the wear on it would be if it had been used for generations. On a chair, most wear would be on the edge of the arms and edge of the seat, on a chest of drawers, the front edge and around the knobs or handles. Lightly rub away the paint in these areas with your sandpaper or steel wool until you achieve the desired look.
You can also make gouges in the surface with the screwdriver, a nail, or a chain. When you're done gouging, rub tinted wax into these areas to darken them.
TIP: DoItYourself's painting consultant Pam Estabrooke of ProTect Painters suggests, "A stain marker is also an option for filling in these areas or adding dark accents into cracks and crevices. It gives you an accent color with the control of a marker."
Step 5--Peel the Paint
You can get even more peeling if you use the heat gun on a low setting over the entire piece of furniture. This technique works whether you've used the one- or two-color painting technique. Finish off your project with a coat or two of matt or satin polycrylic to seal the paint and the "wear."


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NORFOLK – Two teenagers have been arrested after a high speed chase resulted in a crash east of Norfolk.
Stanton County Sheriff Mike Unger says deputies attempted to stop a yellow pickup driving erratically near Highway 35 and E. Benjamin Avenue at around 2:30 a.m. this morning when the pickup sped up and fled east on a county road at a high rate of speed. Unger says the pickup fled for approximately four miles before it eventually lost control and entered the north ditch of the road, rolling multiple times.
The two teens in the pickup then fled the scene on foot. The driver was located and taken into custody about 30 minutes later while attempting to hide behind a group of trees.
The driver, identified as 19-year old Seth Thompson of Creston, was arrested on numerous charges including driving while intoxicated, minor in possession/consumption of alcohol, and operating a motor vehicle to avoid arrest.
The passenger, 19-year old Jesse Schmit of Randolph, was also arrested after being located at a residence at around 5 a.m. He was arrested on charges of minor in possession/consumption of alcohol, obstructing a police officer, and possession of a false driver's license.
Neither driver was injured. The pickup is considered a total loss. The Madison County Sheriff's Office and LifeNet helicopter assisted Stanton County deputies at the scene.


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In an emergency, every second counts!
Reflective house numbers ensure that your property is clearly seen, both day and night. They help everyone in finding your property, taxi drivers, couriers, doctors, postmen, and more importantly, the emergency services. From his experience as an Emergency First Responder, Craig knows only too well how difficult it can be finding houses in the dark, and understands the importance in saving time to potentially save lives.
We now have reflective house signs available for purchase, these signs may be a lifesaving tool that will assist emergency services find you should the need arise. Of course, most emergency service vehicles will have satellite navigation systems, which will bring them very close to your property, but unfortunately, not always to your door. Most emergency service drivers will tell you that finding a property at night is at times extremely difficult. On occasions where time is critical, and more importantly, in a 'life' or 'death' situation, having a reflective house sign on the gate, or on your wall or fence or front door may save valuable seconds in finding you.
These signs are also ideal for identifying site numbers in caravan parks and unit numbers in high density developments such as retirement homes.
It may be worth considering taking a walk to the front of your property to evaluate your house number, or maybe that of an elderly relative or friend. If you were driving down the street, especially at night, how visible is the house number, and could it be located quickly in an emergency? Would having a reflective house sign speed up the time in finding the property in an emergency? We believe these signs are great time saving tools! Remember 'saving time often assists in saving lives'.
For every reflective house sign we sell, we are donating £2 to our local Ambulance Serivce hoping to raise money towards a new and faster fully equipped ambulance, the cost of which is approximately £80,000!
Proceeds will be donated to the East of England Ambulance Service


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Most Strategic Counterplans
Gduchoa posted a topic in CounterplansWith last year's most strategic counterplan being the 50 States CP, this year's is still a mystery to me. I've been across the Canada eh CP but I'm not sure if that one is a good bet and I've used a couple of Advantage CP's as well, though I'm curious about which CP would be the most strategic for this year's topic.


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First National Conference on Recent Trends in Electrical, Electronics, Computing and Information Technology at Jain (Deemed-to-be University), School of Engineering and Technology
Date24 September 2016
9.00 am
JGI Global Campus
45th km, NH - 209, Jakkasandra Post
Bangalore - Kanakapura Main Road
Ramanagara District - 562 112
Jain (Deemed-to-be University), School of Engineering and Technology
About the Event
The objective of the National conference is NCRTEECIT-16 is to provide a forum for scientist, researchers, and engineering for sharing their innovative ideas and thoughts to advance knowledge and to address long-term solutions for methodology in the field of Electrical, Electronics, Computing and Information Technology. The Electrical and Electronics, Electronics and Communications, Computer Science and Information Science Engineering Departments of Jain (Deemed-to-be University) are collaboratively organizing the event at the JGI Global Campus, Jain (Deemed-to-be University).
National Conference
Brochure »


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About This Product
I let my imagination go to a time and place when animalic perfumes reigned supreme. Of course, I included the four traditional animal notes: musk, civet, ambergris, and castoreum with added elements of aged oakmoss, and botanical "animalics"; ambrette co2, labdanum, and hyracium tincture (aka African Stone). The heart is filled with indolic juhi jasmine, orange flower absolute, and gardenia balanced by a slightly sharp and spicy white pepper and aldehyde top note. The result is a lush, provocative, and thoroughly sexy perfume for both men and women.
*EdP / VdP sample vials are 1/2 filled; PERFUME / Extrait & Voile Parfum mini roller vials are full.


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The 1798 Rebellion in Ireland was one of the most defining events in the nation's history, and Swinford, Co Mayo was within an important location of political and military activity. The Brabazons of Swinford played a significant and colourful role. William Brabazon was one of the Swinford United Irishmen – the Society which organised the uprising – and was part of an armed group that turned back some 200 British Dragoons who were trying to reach Castlebar, the county town of Mayo. William along with his compatriots then journeyed to Castlebar themselves and took part in the famous battle between the British and French-Irish forces. The French had landed at Kilalla on the north Mayo coast and proclaimed an Irish Republic. The British lost the Battle but won the war - they regrouped, counter-attacked and finally defeated the French-led army. After the Battle of Castlebar, the French commander General Humbert marched through Swinford and rested at Corley's Hotel in the town's centre, the meeting place and HQ of the local United Irishmen. The soldiers were encamped on the Brabazon demesne and Sir Anthony Brabazon provided two steers and large wrought-iron gates to roast them on for what was in effect a mega BBQ.
After the defeat, the Irish rebels were tried in the courts but many got off. In the Swinford jurisdiction Sir Anthony's youngest brother Edward, who was a local lawyer, successfully defended many of the rebels. The authority in Dublin wrote (in vain) to Sir Anthony, the J.P., instructing him to make Edward desist – they were obviously unaware of Brabazon intransigence (and family loyalties)!
The pics are from a recent 1798 commemoration ceremony in Swinford in which a plaque was placed on the exterior of Corley's Hotel.
Pictures courtesy MichaelMaye.com


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201 6 Theatre Ontario Festival
May 18 - 22, 2016,
QUONTA, Gateway Theatre Guild, École Publique Odyssée
480 Norman Avenue, North Bay, ON
Wednesday, May 18
7:30pm Curved by Kristin Shepherd Gateway Theatre Guild
(North Bay) QUONTA
(Northeastern Ontario)
Thursday, May 19
7:30pm Boeing Boeing by Marc Camoletti (translated by Beverly Cross & Francis Evans) Northumberland Players
(Cobourg) EODL
(Eastern Ontario)
Friday, May 20
7:30pm 33 Variations by Moises Kaufman Theatre Sarnia WODL
(Southwestern Ontario)
Saturday, May 21
7:30pm The Drowning Girls by Beth Graham, Daniela Vlaskalic and Charlie Tomlinson The Curtain Club
(Richmond Hill) ACT-CO
(Greater Toronto Area and Central Ontario)
Theatre Ontario Fesival 2016 adjudicator:
Mimi Mekler.
Mimi Mekler's work as director, actor, dramaturge, writer and adjudicator has taken her from California to Czechoslovakia and Italy to Israel. She is a professor in the Acting Discipline at Sheridan College's Music Theatre Department. She also teaches for the joint Theatre and Drama Studies programme at Sheridan and University of Toronto at Mississauga, and for the Digital Character programme for Sheridan's acclaimed Computer Animation.
2016 Theatre Ontario Awards
The Elsie For Outstanding Festival Production
Boeing Boeing, Northumberland Players
Honourable Mention
The Drowning Girls, The Curtain Club
Outstanding Director
Joan Burrows, The Drowning Girls
Honourable Mentions
James Finan, Boeing Boeing
Henri Canino, 33 Variations
Outstanding Performance by a Female
Audrey Hummelen as Dr. Katherine Brandt, 33 Variations
Honourable Mentions
Patsy McVicars as Wavy, Curved
Tanya Webb as Del, Curved
Outstanding Performance by a Male
Jamie Hunt as Robert, Boeing Boeing
Outstanding Performance by a Male in a Supporting Role
David Hoare as Bernard, Boeing Boeing
Honourable Mention
Darryl Heater as Mike Clark, 33 Variations
Outstanding Performance by a Female in a Supporting Role
Andrea Hughes Coleman as Dr. Gertie Ladenburger, 33 Variations
Honourable Mention
Johanna McPherson as Chloe, Curved
Outstanding Visual Presentation
Boeing Boeing (James Finan, Set Designer; Ken & Jody Forsyth, Set Décor; Joe & Diana Flynn, Properties; Jamie Finan, Costume Designer; Mary Smith & Melissa Thornton, Make-up & Hair)
Honourable Mentions
Curved (Arndt Vonholtzendorff, Set Designer)
The Drowning Girls (Wayne Milliner, Set Designer; Mark Hayward, Lighting Designer)
Outstanding Technical Achievement
The Drowning Girls (John Willcock, Master Plumber)
Honourable Mention
33 Variations (Alexandra Weselaken, Projection Design)
Outstanding Coordinated Production
(This award is chosen by the Festival Stage Manager)
Northumberland Players
Special Adjudicator Award
For outstanding ensemble:
Tamara Van Bakel as Bessie, Nicole Wahl as Alice & Shelly Meichenbaum as Margaret, The Drowning Girls
Special Adjudicator Award
"The Cherry on Top Award" for that special something in a curtain call:
Alina Adjemian, choreographer, Boeing Boeing
Special Adjudicator Award
"The Taboo Award" - For openness in dealing with difficult subjects:
The cast (Johanna McPherson as Chloe, Tanya Webb as Del, Joanne Bernier as Estelle, June Keevil as Granny Wave, Stephanie Haines as Nurse & Patsy McVicars as Wavy), Curved
Special Adjudicator Award
"The Theme and Variation Award":
Dan Sonier, the pianist, 33 Variations
Special Adjudicator Award
"The 3 Cs Award" - For Creativity, Commitment and Comedy:
Kristy Bird as Gloria, Helen Pitt Matthew as Berthe, Jody Ledgerwood as Gabriella
& Anne-Marie Bouthillette as Gretchen, Boeing Boeing


text:
- Software
- Open Access
The InDeVal insertion/deletion evaluation tool: a program for finding target regions in DNA sequences and for aiding in sequence comparison
- Sierra D Stoneberg Holt1Email author and
- Jason A Holt2
© Stoneberg Holt and Holt; licensee BioMed Central Ltd. 2004
- Received: 07 May 2004
- Accepted: 29 October 2004
- Published: 29 October 2004
The program InDeVal was originally developed to help researchers find known regions of insertion/deletion activity (with the exception of isolated single-base indels) in newly determined Poaceae trn L-F sequences and compare them with 533 previously determined sequences. It is supplied with input files designed for this purpose. More broadly, the program is applicable for finding specific target regions (referred to as "variable regions") in DNA sequence. A variable region is any specific sequence fragment of interest, such as an indel region, a codon or codons, or sequence coding for a particular RNA secondary structure.
InDeVal input is DNA sequence and a template file (sequence flanking each variable region). Additional files contain the variable regions and user-defined messages about the sequence found within them (e.g., taxa sharing each of the different indel patterns).
Variable regions are found by determining the position of flanking sequence (referred to as "conserved regions") using the LPAM (Length-Preserving Alignment Method) algorithm. This algorithm was designed for InDeVal and is described here for the first time.
InDeVal output is an interactive display of the analyzed sequence, broken into user-defined units. Once the user is satisfied with the organization of the display, the information can be exported to an annotated text file.
InDeVal can find multiple variable regions simultaneously (28 indel regions in the Poaceae trn L-F files) and display user-selected messages specific to the sequence variants found. InDeVal output is designed to facilitate comparison between the analyzed sequence and previously evaluated sequence. The program's sensitivity to different levels of nucleotide and/or length variation in conserved regions can be adjusted. InDeVal is currently available for Windows in Additional file 1 or from http://www.sci.muni.cz/botany/elzdroje/indeval/.
- Region File
- Sequence File
- Probable Alignment
- Conserve Region Sequence
Gaps caused by insertion and deletion events (indels) are often important features of DNA sequence data, which is widely used in phylogenetic studies [1–13]. Although some authors consider indels to be potentially misleading [1, 14], others consider indels to be important characters [8, 9, 13, 15, 16] and have argued that treating them as missing data can weaken phylogenetic analyses [3, 7, 10, 17]. Even though it is generally accepted that indels that cannot be unambiguously positioned make confident homology assessment impossible and, therefore, regions that contain them should be excluded from phylogenetic analyses [3, 4, 6, 8], it has been proposed that even these regions are valuable if properly coded [15].
Phylogenetic estimation depends on accurate character homology assessment (sequence alignment) [4, 8, 18], which is made more difficult by the presence of indels [2–4, 6, 8, 15]. Indel occurrence is context-dependent, and it has been repeatedly reported that indels tend to be found clustered into specific length-variable regions [1, 3, 5, 6, 8, 19–21]. Accurate assessment of these regions (proper alignment and recognition of relative indel rate, reversals, parallel events, and multiple, overlapping events) is aided by comparison among many sequences from various taxonomic levels [4, 8, 19].
Sequence comparisons are complicated by the ambiguities gaps introduce into alignments. Finding a target region recognized from one alignment within another can be time consuming and difficult to perform accurately. Because of the limits of computer screen size and human analytical ability, alignments of hundreds of sequences are difficult to evaluate, even when they can be prepared.
Poaceae is one of the largest families of flowering plants and is economically important [22]. Lower-level phylogenies within the family often make use of the largely non-coding plastid sequence between the trn L (UAA) 5' exon and trn F (GAA), hereafter called trn L-F [17, 23–28]. As of Apr 2, 2004, the NCBI Entrez Nucleotides database [29] contained 505 Poaceae trn L-F sequences. Comparing indel regions across these sequences can reveal patterns in indel behavior and aid researchers in creating accurate alignments. A discussion of the indel regions in these sequences is being prepared separately for publication.
The program InDeVal was originally developed to help researchers find known indel regions (with the exception of isolated single-base indels) in newly determined Poaceae trn L-F sequences and simultaneously compare them with 533 previously determined sequences (those mentioned above, plus 28 determined by SDSH). It is supplied with input files designed for this purpose. More broadly, the program is applicable for finding specific target regions (referred to as "variable regions") in DNA sequence. A variable region is any specific sequence fragment of interest, such as an indel region, a codon or codons, or sequence coding for a particular RNA secondary structure. The LPAM algorithm, which was specifically designed for InDeVal, is used to find sequence (referred to as "conserved regions") flanking the variable region in the analyzed sequence. InDeVal can find multiple variable regions simultaneously (28 indel regions in the Poaceae trn L-F files). The program's sensitivity to different levels of nucleotide and/or length variation in conserved regions can be adjusted.
Input files
This table summarizes the inputs and outputs for InDeVal. It provides the names of the different InDeVal file types and displays, the number involved in analyzing a single portion of DNA, whether or not they are required for InDeVal function, their basic format, whether or not they are provided with the InDeVal package, when they are produced, and a brief description.
Conserved region file
Representative sequence with variable regions replaced by variable region file names
Variable region file
Yes (28)
List of sequences for which a variable region is to be searched and a message to be displayed for each
DNA sequence file
Set of sequences to be analyzed
Sequence Analysis Window
One per analyzed sequence
Displays analyzed sequence broken into user-defined units and allows InDeVal/user interaction
Variable Region Analysis Window
One per variable region
Upon user-request
Displays one variable region so that the sequence found in the analyzed sequence can be contrasted with those found in all other studied sequences
Output file
One per analyzed sequence
Upon user-request
Similar to NCBI default display
Text file of the analyzed sequence, annotated with conserved and variable region positions and variable region sequence-specific messages
A conserved region file contains at least one template, created by taking a representative sequence, removing the variable regions, and replacing them with variable region file names (Additional file 2). Multiple (15) templates were used in the Poaceae trn L-F sequences to accommodate single, large deletions that spanned otherwise conserved regions. Treating them the same as the other indels would have resulted in a few large, difficult-to-interpret variable regions. InDeVal performance is improved by designing templates with conserved regions at least 20 bases long on either side of each variable region. However, the program still functions using templates with only one conserved region, conserved regions only 4 bases long, and variable regions flanked by other variable regions (such as clearly distinguishable, adjacent indel regions varying at different rates, which are found in Poaceae trn L-F). Although InDeVal parameters can be adjusted to reflect different degrees of nucleotide and length variation in conserved regions, it is a good idea to use a representative sequence for template design, especially if some conserved regions are short. Additional templates can be designed to accommodate distantly related taxa. (In the Poaceae trn L-F files, separate templates were designed for Pooideae, Ehrhartoideae, and the PACCAD clade).
A variable region file contains the sequence variations the researcher expects in the region and some output information about each variation (Additional file 2). In the Poaceae trn L-F files, the output information is the list of taxa with each variation. For coding sequence, the output information could be the amino acids for which the variations code. If the user is interested only in knowing if a particular variation is present, the output could be simply "Yes". Variants not found in the variable region file are also reported by InDeVal. The program works if the variable region file is completely blank (variable regions are all bases found between template conserved regions), but it obviously cannot provide output messages in this case. Symbols can be used in variable region sequence to draw attention to specific features of interest. They are ignored during alignment, but are displayed in the Variable Region Sequence List Box (Additional file 2). The Poaceae trn L-F variable region files include spacing that emphasizes repeat motifs, hyphens to indicate that an entire variable region has been deleted, and stars to indicate possible inversion sites. InDeVal can help the user create these input files, comparing new sequences to those already included and indicating what adjustments should be made.
Sequence files are in a less stringent FASTA-format (Additional file 2) and can be in either orientation. They can include spaces, numbers, capital or small letters, IUPAC ambiguity symbols, and carriage returns without disrupting InDeVal function.
A conserved region file (TemplatePtrnLF.txt) and 28 variable region data files, designed from 533 Poaceae trn L-F sequences, are provided with InDeVal. These files are based on the first author's critical examination (to be published elsewhere) of various alignments of these sequences using the web-based programs BLAST 2 SEQUENCES [30] and/or CLUSTAL W multiple alignments [31].
Aligning a sequence with a given template
Sometimes conserved regions are not found or are found at multiple locations within their subsequence. The program records this information and proceeds to the next longest sequence. A conserved region that cannot be aligned is recorded as "not found." A conserved region with multiple possible alignments is recorded as "found", but none of its possible alignments is used to limit the searches for the remaining regions.
This template alignment algorithm preserves the ordering found in the template, giving priority to the alignment suggested by the longer conserved regions, which are assumed to be more reliable. Using the alignment of longer regions to reduce the search space for smaller regions minimizes the probability of finding ambiguous or incorrect alignments.
Length-Preserving Alignment Method (LPAM)
InDeVal uses the LPAM algorithm, designed specifically for InDeVal and described here for the first time, to align the conserved regions within their subsequences. LPAM divides a conserved region into overlapping "words", strings of sequence of a user-defined length. That is, given a 4-base word length, the sequence "caatgt" would be represented as "caat", "aatg", "atgt". (Conserved regions shorter than the word length are found only if they match exactly.) LPAM searches the analyzed sequence for each of these words and notes multiple finds, single finds, and missing words. Each word is allowed one "vote" for a possible alignment, i.e., for the base in the analyzed sequence that begins the conserved region. If the word occurs once, it casts its vote for that alignment. If it occurs multiple times, its vote is divided equally among the possibilities. Words that are not found cast no vote. The alignment that receives the most votes is assumed to be the most probable.
LPAM permits a (user-definable) degree of length variation. A word's possible alignments are evaluated according to whether or not they agree with the most probable alignment for the region as a whole. Suppose, for example, that the most probable ungapped conserved region alignment would begin at base 53. If the tolerance is set to 3, LPAM will allow the first word to begin at any base from 50 to 56, preferring the possibility closest to 53. If the first word in the conserved region sequence has no acceptable alignment, LPAM searches for the first word that does have an acceptable alignment. All bases preceding this first found word are aligned with no gaps. In the above example, if the first and second words are not found and the third word aligns beginning at base 57, the first two bases of the conserved region will be aligned with bases 55 and 56.
Each subsequent base is aligned similarly. If the word it begins has no acceptable alignment, the base is aligned according to the previous acceptable word. If the word it begins has multiple acceptable alignments, the one closest to the previous alignment is chosen. Note that the range of acceptable alignments remains constant; it is a function of the initial voting and does not depend on any of the choices made in aligning individual bases.
The aligned bases from the analyzed sequence are compared with the template conserved region sequence, and a percentage similarity is established. If this is greater than the user-defined cut-off value, the conserved region is listed as found.
InDeVal then checks the most probable alignment that clearly differs from the first. (In the example above, this excludes any alignment beginning at bases 50–56.) If this alignment also yields a percentage similarity greater than the cut-off value, neither is selected, but the region is still considered to be "found" for purposes of measuring similarity to the template (see below).
The LPAM algorithm is able to align conserved regions despite both point mutations and indels. However, deletions in the first or last word of a conserved region are indistinguishable from point mutations (and are interpreted as such). LPAM proved effective in the Poaceae trn L-F sequences, where conserved regions are by definition length-conserved. In 533 sequences, there were only three instances where an indistinguishable mismatch was caused by an indel instead of a point mutation and resulted in misalignment. It is important to design templates so that the ends of conserved regions are not in sequence prone to indel activity.
The alignment suggested by LPAM is not necessarily locally maximal, i.e., there are cases where a slight adjustment of the alignment would produce a higher percentage of matched bases. Furthermore, a number of factors can prevent LPAM from finding a correct alignment. Repetitive sequence, resulting in multiple matches, can be very problematic. InDeVal may not be appropriate for analyzing repetitive sequence, and if it is used for this purpose, templates must be designed with great care. If every word contains a point mutation, the conserved region cannot be found. Indels can cause problems if they are dispersed so that several words are disrupted. In general, LPAM will correctly align regions if the mutations are clustered and the first and last base can be assigned correctly (which will be the case if they have no indels between them and the undisrupted word that will position them). Though hypothetical situations where LPAM would create incorrect alignments are easy to envision, in practice, the algorithm proved able to reliably determine where the conserved regions of a sequence begin and end. This is sufficient for the purposes of InDeVal. It is important to note that even when LPAM does not find a conserved region alignment, a possible alignment is displayed, and the user can rearrange it (to a limited extent) and interpret it.
Choosing the best template
If two templates have roughly equal found conserved region scores (to within a user-selected tolerance), the one with the higher "score percentage" (calculated by dividing the score by the total number of conserved region bases in the template) is ranked higher. This ensures that sequences that actually do have deletions will be matched with deletion templates, even though the templates (theoretically) have an equal number of bases in found conserved regions (Figure 2).
All the templates are ranked in this way and listed in the Template List Box in order. The highest ranked template is automatically selected, and its variable regions are analyzed. The user has the option of comparing the sequence to a template other than the one selected by InDeVal.
Finding the correct variable region sequence
Each variable region is defined as the sequence between two specific conserved regions. If both flanking conserved regions are found, the bases between them are recorded, and the appropriate variable region file is searched for a matching string of bases.
Sequence between two found conserved regions is classified as a confused region if the template indicates that it should contain one or more conserved regions that were not found. Because the variable regions in a confused region are not clearly delimited, InDeVal searches the entire region for each variable region sequence in each applicable variable region file, and all potential matches are recorded. The user is able to select from among these possibilities, rearrange the display to reflect them, and study different sequence interpretations. In this manner, InDeVal is able to deal satisfactorily with most short conserved regions that cannot be found because of point mutations. In the Poaceae trn L-F file, one- and two-base conserved regions were incorporated into adjacent variable region files because they were impossible to find.
A short conserved region will be misaligned if a point mutation prevents it from being found in the proper place and a perfect match is found nearby. If this occurs, it is possible to set the program to disregard conserved regions of this size. (This situation has only been observed for 4- and 5-base conserved regions). The region can then be satisfactorily parsed using the confused region algorithm.
Results and discussion
InDeVal has two output windows (Table 1, Additional file 2). The Sequence Analysis Window displays the analyzed sequence broken into conserved and variable regions and lists template information. From this window, the user can load template and sequence files, export the analysis to a text file, set LPAM parameters and warning message options, convert the sequence to its complement prior to analysis, and choose a template other than the one selected by InDeVal. For conserved regions, the template sequence is listed so that it can be compared directly with the analyzed sequence. For variable regions, if the analyzed sequence matches one of the variants in the variable region file, the message for that variant is displayed.
The Variable Region Analysis Window displays the variable region file name, variants proposed by InDeVal, and the sequence and length of the line currently selected in the Sequence Analysis Window (which can be any line from any sequence). The user can request displays of some or all of the sequences in the variable region file.
A text file can be created once the user is satisfied with the display in the Sequence Analysis Window. This file gives information about the sequence and template, lists the positions of the various conserved and variable regions, and shows the entire analyzed sequence. The user can choose whether or not variable region file information is displayed.
InDeVal for the Windows platform is available in Additional file 1. The source code for InDeVal in Microsoft Visual Basic 6.0 is available in Additional file 3. InDeVal analyzes only DNA sequences, but a version for protein sequences could be created using the source code. It would have to be altered to recognize amino acid sequence (all non-nucleotide letters are presently ignored), and an algorithm to recognize frame-shifts would be helpful.
InDeVal is a program designed to search DNA sequence for target regions and to display information about them. It can find multiple target regions simultaneously and is relatively robust when challenged by conserved region variation and differences among analyzed sequences in length, spanned region, and format. InDeVal differs from other alignment software in that it breaks the analyzed sequence into user-defined units and emphasizes regions that are of most interest to the user. This makes it possible to quickly compare specific features among many hundreds of sequences. An advantage of InDeVal is that, while it can be used to quickly skim and classify hundreds of sequences, it displays all surrounding sequence. Therefore, if at any time questions arise about the initial classification, the researcher can recreate the InDeVal alignment, instantly find the area in question, and study it for alternative explanations.
Availability and requirements
Project name: InDeVal
Project home page: http://www.sci.muni.cz/botany/elzdroje/indeval/
Operating system(s): Windows Platform
Programming language: Microsoft Visual Basic 6.0
Other requirements: None
License: None
Any restrictions to use by non-academics: No restrictions
The authors wish to thank P Bureš for helpful discussions and advice and three anonymous reviewers for constructive suggestions. This research was undertaken during the graduate studies of SDSH, supported by a US National Science Foundation Graduate Research Fellowship, a US Student Fulbright Grant, and an Honor Society of Phi Kappa Phi Fellowship, and was supported in part by the Ministry of Education of the Czech Republic FRVŠ Project 556-G4 (Phylogenetic analysis of Poa L. on the basis of non-coding cp DNA sequences) and Research Project MSM 143100010 (Spatial and Temporal Biodiversity Dynamics in Ecosystems of Central Europe).
Authors' Affiliations
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- Catalán P, Torrecilla P, López Rodríguez JÁ, Olmstead RG: Phylogeny of the festucoid grasses of subtribe Loliinae and allies (Poeae, Pooideae) inferred from ITS and trn L-F sequences. Mol Phylogenet Evol 2004, 31: 517–541. 10.1016/j.ympev.2003.08.025View ArticlePubMedGoogle Scholar
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This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


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I have a very good friend whose wife is living with manic depression. He explained to me that there are many times when she threatens to leave and talks about committing suicide. She even discusses how she will kill herself. My friend feels that, in these instances, he must do everything he can to keep his wife from leaving. If he doesn't, he is terrified that it will be the last time he sees her alive. My question, therefore, is how much responsibility is one supposed to take for the decisions made by another with a mental illness? I understand that being bipolar is a very serious condition, but I feel that my friend's wife has trapped her husband in a codependent position with her threats. Maybe I'm wrong, and he is doing the right thing. I just can't imagine living day to day with the burden of being accountable for another adult's every action. Please give me some advice as to how I can be of help to my friend. Thank you!
- Dr. Dombeck responds to questions about psychotherapy and mental health problems, from the perspective of his training in clinical psychology.
- Dr. Dombeck intends his responses to provide general educational information to the readership of this website; answers should not be understood to be specific advice intended for any particular individual(s).
- Questions submitted to this column are not guaranteed to receive responses.
- No correspondence takes place.
- No ongoing relationship of any sort (including but not limited to any form of professional relationship) is implied or offered by Dr. Dombeck to people submitting questions.
- Dr. Dombeck, Mental Help Net and CenterSite, LLC make no warranties, express or implied, about the information presented in this column. Dr. Dombeck and Mental Help Net disclaim any and all merchantability or warranty of fitness for a particular purpose or liability in connection with the use or misuse of this service.
- Always consult with your psychotherapist, physician, or psychiatrist first before changing any aspect of your treatment regimen. Do not stop your medication or change the dose of your medication without first consulting with your physician.
Your concern for your friend is wonderful to hear. The question you ask doesn't have a 'right' answer, however, only a culturally normal one and one arrived at by an individual in that situation. In lieu of an answer I'll share some facts and some impressions. First – Your friend is not crazy to be afraid of his wife's capacity for suicide. Bipolar Disorder (and Depression in general) are lethal disorders with a small but substantial minority of persons suffering with these disorders eventually committing suicide. It isn't clear, however, that his staying with her will provide her with adequate protection from suicidal impulses when she is in a crisis – they both might be best off bringing her to an emergency room when she is suicidal – to provide 24 hour supervision and stabilization of her condition. True full-on Bipolar disorder cannot be effectively treated (to the best of my knowledge) without pharmacological intervention. There is another angle to this – and that is your friends' psychological investment in being present for his wife. Such a role might be an important part of how your friend views himself and his contribution to the marriage. Your attempts to tamper with this role (even it if it is destructive for him to carry out) might only earn you his animosity. If you must say something to your friend here then gently tell him – once – of your concern that he is harming himself. You can also indicate your availability for support should he need it. If he indicates that you need to back off – then do so. Ultimately – your friend has to decide this one on his own.


text: Rudi Ahlers wrote: > Here's my verbose output: [..] > + Found item [ifName='lo'] index: 1 [from value] > + Found item [ifName='peth0'] index: 2 [from value] > + Found item [ifName='sit0'] index: 3 [from value] It certainly looks like cacti is finding a bunch of stuff, what does the status column say to the left of the green circle? For my test system it says - Success [24 Items, 4 Rows] When you go to the 'Create graphs for this host', do you see just the Header with nothing below it? (Data Query [SNMP - Interface Statistics]) What version of cacti? Though it shouldn't matter this is a pretty basic thing. nate


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Wildlife Gardening
1. Grow a mixture of native and non-native plants to provide nectar and pollen for bees and other insects. Choose plants that flower at different times of year to ensure that pollen and nectar are available over a long period. Select trees and shrubs with berries for birds and other animals.
2. Create a water feature in your garden. A pond, ideally without fish, will enable amphibians and dragonflies to breed. If a pond is not practical, a simple bird bath or pebble fountain will provide a place for animals to drink.
3. Delay cutting back perennials until the spring. The seed heads that remain provide valuable food for birds and other animals through the winter, while the stems and foliage provide valuable shelter for hibernating insects.
4. Recycle your organic kitchen and garden waste to create compost for the garden. The compost heap will not only provide you with an excellent soil conditioner but will also be home to invertebrates and other animals, and is a rich feeding ground for birds and beetles.
5. Create additional habitats for wildlife by growing climbing plants against bare walls and fences. These provide valuable cover and food for birds, insects and mammals, as well as adding extra interest to the garden.
6. Dead wood is a valuable habitat, supporting a wide range of invertebrates. Dead wood can be used to create a simple wood pile or interesting sculptural feature.
7. Help wildlife by providing additional features such as bird and bat boxes, solitary bee nests and bird feeders. Birds can be provided with food, either bought seed or food scraps, throughout the year.
8. Consider leaving part of your lawn uncut. Long grass is an excellent habitat for grasshoppers, beetles and young amphibians, and provides roosts for insects such as damselflies. Grasses are also important food sources for the caterpillars of some butterflies.
9. Where possible, use mulches to control weeds, select disease resistant varieties of plants and use cultural or biological control methods to combat pests. Encourage a natural balance to develop by having as wide a range of plants and animals as possible.
10. Think carefully about the origin of anything you buy for your garden. Ensure that plants come from cultivated stock and that the use of any material, such as potting compost, does not put a habitat under threat, whether in the UK or abroad.


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A real estate professional, Janet Ibru serves as Executive Manager at CASI Global Investments Corporation in Dubai. Through her firm, Janet Ibru presents investment opportunities to and manages the investments of international clients.
Some global property experts have predicted that Dubai will enjoy one of the world's leading real estate markets in 2013. Specifically, it has been projected that there will be an increase in the luxury villa market of between five and 10 percent in Dubai neighborhoods such as Palm Jumeirah and Emirates Hills. Researchers report that the market rise derives from an influx of foreign business professionals from the United Kingdom and Asia.
Significant real estate market gains have also been forecasted for elsewhere in the world, particularly in Moscow and Miami. It has been reported that prime residential property values in more than a dozen international cities will increase approximately 2.5 percent in 2013.


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Today is not just like any other day at the bog. There's the usual massive amount of laundry waiting in the hall, and the pony is giving me the fishy eye waiting to be fed, and there are piles of stuff waiting to be organized, but it's a special day. It's the birth of my blog.
All the usual questions are evident: What will it look like? Will it be funny? Will it be smart? Will people like it? Will it be easy and fun or a pain in the butt every day?
I've watched and lurked on others' blogs; I've laughed and cried at what they have written. Many times I've wished for a place to vent my frustrations, tell something funny, ask for advice outside of my small-town circle of friends. But was there time in my life for another thing? I finally had to admit that there had to be time for THIS thing; this thing for me.
So TA-DA! Today I took the plunge, started the blog, pictures and all, and....
Gee, nothing funny happened today. And it's after 4. There was a brief humorous conversation I had with Jones about where I would have to take his temperature if he wouldn't open his mouth or take off his shirt so I could get to his armpit...
But after all I'm just meeting some of you and don't want to be tacky first time out.
Maybe for today, just getting out here and saying "hi there" is enough. My family is hanging out behind me saying "We want to see the blog! Can we see the blog now?!"
So we'll see what tomorrow brings. For now, Happy Blog-day to me.
3 hours ago


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Jane Whelen-Banks
The Lovable Liam Series
This set of six books follows the everyday adventures of Liam as he tries to make sense of the world around him. Covering topics such as how to greet friends appropriately, how to apologise and how to lose with grace, children can learn with Liam about basic social skills and how to cope with a variety of situations.
Lovable Liam
Affirmations for a Perfectly Imperfect Child
Liam is lovable even when he whines and won't eat his dinner. When people are cross with Liam, they still love him. Being cross will only last a minute. Love will last forever! Lovable Liam reminds parents to let their child know they are wonderful and precious, deeply valued by friends and family, even when people are cross with them.
Liam Knows What To Do When Kids Act Snitty
Coping When Friends are Tactless
In Liam Knows What to do When Kids Act Snitty, lovable Liam finds out why his amazing feats of greatness are sometimes met with snide or snitty responses. He learns that when kids are snitty, it does not mean they don't like you, or that your tricks are boring, but that they haven't yet learnt how to be gracious and polite.
Liam Says "Hi"
Learning to Greet a Friend
In Liam Says "Hi" Liam manages to overcome his shyness and complete the steps necessary when greeting a friend at the front door. Vibrant, colourful and lively, this book's positive messages and advice are ideal for young children wanting to understand social situations or how friendships work.
Liam Goes Poo in the Toilet
A Story about Trouble with Toilet Training
Liam Goes Poo in the Toilet illustrates the relationship between eating and excreting. It provides visual instructions on how to "relax and push". After much fanfare, Liam finally masters going 'poo' in the toilet, and both he and Mum bask in the glory of a job well done.
Liam Says "Sorry"
Repairing an Encounter Gone Sour
In Liam Says "Sorry" Liam impulsively whacks his brother on the nose and ruins an otherwise joyful round of wrestling. Wanting desperately to resume the game and win favour with his brother, Liam accepts responsibility for his blunder and apologises. His brother forgives him, and apologises too and the wrestling at last can be resumed.
Liam Wins the Game, Sometimes
A Story about Losing with Grace
In Liam Wins the Game, Sometimes, lovable Liam learns that it is ok to feel disappointed if you don't win, but that it's not ok to moan or cry or throw things: sometimes you win and sometimes you don't. He learns how to become a good sport, and that makes him a real champ!
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8. Stainless steel appliances
Percentage of home buyers willing to pay more: 41%
Amount willing to pay extra: $1,850
Like most features, stainless steel appliances are most important to people between the ages of 35 to 54, with 23% considering them to be a "very important" investment, compared with just 16% of those under the age of 35 and a mere 11% of those over the age of 55. From a cost perspective, stainless steel appliances are not necessarily the best investment. Stainless steel wears out far easier than most other common materials. Also, the children in the house can also get their fingerprints on the appliances, requiring more cleaning. However, people are primarily driven to buy stainless steel appliances because they look more attractive.


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This is who we are. We realize that our people are what make the difference.
Join our growing team of customer-oriented people who have a high standard of excellence and help us fulfill our mission to provide value for our customers!
Automate record updating and improve system-to-system communication for some of the most popular electronic health record systems in use.
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Manage scripts and script scheduling across multiple machines from any location.
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Benchmark your Revenue Cycle processes against other leaders in healthcare to see where you can benefit from Robotic Process Automation (RPA).
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text:
https://www.w3.org/Bugs/Public/show_bug.cgi?id=16373 Summary: replacing a child creates extra mutationrecord Product: WebAppsWG Version: unspecified Platform: PC OS/Version: Linux Status: NEW Severity: normal Priority: P2 Component: DOM AssignedTo: email@example.com ReportedBy: email@example.com QAContact: email@example.com CC: email@example.com, firstname.lastname@example.com Replacing a child should create just one record, which has the old child in the removedNodes, and new node in the addedNodes. Currently the spec creates separate records. -- Configure bugmail: https://www.w3.org/Bugs/Public/userprefs.cgi?tab=email ------- You are receiving this mail because: ------- You are on the CC list for the bug.Received on Wednesday, 14 March 2012 16:39:49 UTC
This archive was generated by hypermail 2.3.1 : Tuesday, 20 October 2015 10:46:19 UTC


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Mere SurgeryDark Lane, MereWarminsterWiltshire, BA12 6DTTel: 01747 860001
Patient Feedback
"Very Caring, efficient and happy practice. All the partners pleasant."
"Having the physio available in the surgery is wonderful"
"Generally I thing the Mere surgery is well run and is an asset for the village"
"A Doctor is available to talk to everyday (Mon-Fri), our prescriptions service is second to none. Very well organised practice – everyone very helpful"
"I strongly feel that the care my family and I receive from the Mere Practice is excellent and that everyone in the practice has that "can do" attitude that makes it work so well"
"The ancillary staff (nurses and reception staff) whose demure remains welcoming, cool, calm and collected even when at their busiest"
"I feel totally at ease with the care, advice and help provided by the practice"
Here's a checklist of the vaccines that are routinely offered to everyone in the UK for free on the NHS, and the age at which you should ideally have them.
2 months:
3 months:
4 months:
Between 12 and 13 months:
3 years and 4 months, or soon after:
Around 12-13 years:
Around 13-18 years:
65 and over:
Click here for the recommended HPA vaccination schedule
Influenza – flu – is a highly infectious and potentially serious illness caused by influenza viruses. Each year the make-up of the seasonal flu vaccine is designed to protect against the influenza viruses that the World Health Organization decide are most likely to be circulating in the coming winter.
Regular immunisation (vaccination) is given free of charge to the following at-risk people, to protect them from seasonal flu:
These links all come from trusted resources but if you are unsure about these or any other medical matters please contact your doctor or pharmacist for advice
Copyright 2006 - 2019 My Surgery Website | Privacy & Usage | Edit | Staff Home | Site Map | Accessibility | Site T&C's | Service T&C's


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Thank you for your donation to "Facets of Joy"!
May the action of donating magnify abundance within your life in the areas that you wish and may you feel my immense joy and gratitude as I graciously receive this gift!
I would like to gift you with this PDF download of "A Celebration of Your Presence" – photo affirmations that celebrate *essence*. May you enjoy it!
Much peace and abundant love,


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photo of the Depot Building by John Morris
Years ago, we were excited when the Depot Building in the Warehouse District started filling up with tenants. Unfortuantely, all of those tenants were nightclubs that only brought foot traffic to that area at night. The Warehouse District was almost solely a nighttime district. This has changed drastically in the past two years with more day time additions popping up in West of Dawson Street. From the Contemporary Art Museum, to the new VAE space, to Tasty Beverage Company, Spy Raleigh and a handful of new restaurants, the Warehouse District is slowlying becoming the place to be in Downtown Raleigh, day or night.
The latest addition to The Depot Building that currently houses Jibarra, Tasty Beverage Company, Tuscan Blue and The Union will be Videri Chocolate Factory. According to WRAL, the owners (who used to work for Escazu) are bringing in a full production line for milk and dark chocolate and eventually the ability to bring your own beer and wine. Yes, please! Videri will open in the space formerly occupied by Ess Lounge on Davie Street. This is the first time that the Depot Building has been full of tenants since that disaster trio of bars that crashed and burned back in 2007. It's nice to see it full again, with a variety of tenants.
This isn't the first chocolate factory to open in the Downtown Raleigh area. We have been huge fans of Escazu since they popped up on Glenwood South back in 2008 and then moved over beside Market Restaurant in the Mordeci area. I'd say downtown is a big enough place for two chocolate factories.
Restaurants, Other posts by Jedidiah.
Downtown RaleighWarehouse DistrictDepot BuildingChocolateVideri Chocolate Factory
As a frequent Jibarra customer and a big lover of chocolate, I am very excited about this.
when is Raleigh going to get a booze distillery? Otis' Secret Stash must happen.
" ...eventually the ability to bring your own beer and wine."
Yes, please.
That's linked to WRAL, not the N&O.
Errr….Thanks Cindy.
I love Escazu…I'll give this new one a try, but I can't imagine a better chocolate shop.
Isn't there yet another chocolate place downtown? Maybe not a factory but a shop? Like Glenwood South, towards the Hillsborough end?
RaleighRob -
Escazu used to have a retail shop on Glenwood South. But they consolidated it into their workshop, which is at North Blount, near Mordecai/Peace College. It's right next to Market Restaurant as well.
Like brian_M said, I can't imagine any new place being better than Escazu!
There was a chocolate shop called Peche de Chocolat on Glenwood near Hillsborough. I'm not sure if it is still there, but it was pretty good.
I'm still confused as to why the state (NCRR) still owns this building. Why don't they sell it?
Isn't Videri the third word of our State Motto? And doesn't it mean "seem"? Seems like an odd name for a chocolate shop.


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Jack Mitchell in his studio, 2005
Photograph by Craig B. Highberger
Jack Mitchell
by Craig B. Highberger
I first became aware of Jack Mitchell's extraordinary photographs when I was in high school in Pittsburgh, Pennsylvania. I purchased a copy of After Dark magazine with one of Jack's lush images on the cover. There were more inside. I began to anticipate each issue and look for his photographs. I saved all of those issues, too. Little did I know that more than 30 years later I would make a feature-length documentary about Jack's life and work.
Jack Mitchell was born in Florida in 1925. His father taught him basic photography and he became an avid reader of photography magazines. He was first published in a national photography magazine when he was 15 years old. The photograph was a carefully composed portrait in profile of his art teacher using Rembrandt lighting. Jack got his first press card in 1942 at the age of 16, from the Daytona Beach and New Smyrna Beach Observer for which he photographed movie star Veronica Lake who was on a War Bond tour and Victor Mature who was appearing in the U.S. Coast Guard show "Tars and Spars".
After high school Jack was drafted into the U.S. Army, serving in the Infantry. He later became a U.S. Army Public Relations Photographer. He was stationed in Florence and Venice, Italy. In 1950, several years after returning to the U.S., he moved to New York City. At the suggestion of modern dance pioneer Ted Shawn, he at first concentrated on photographing dance and dancers. William Como, editor of Dance Magazine (and later editor and publisher of After Dark magazine) began assigning Jack to shoot photographs. The July, 2003 issue of Dance Magazine featured his 168th cover photograph for that publication.
In 1957 Jack met Bob Pavlik. Within a few weeks they moved together into a large apartment at East 74th Street and York Avenue with adequate space for a studio, a darkroom, and living. Bob became Jack's business and life partner.
In the 1960's The New York Times Arts and Leisure section editor Seymour Peck became aware of Jack Mitchell's work and began assigning him to photograph major creative and performing artists of all disciplines. Mitchell's photographs have also appeared on the covers of and in The New York Times Magazine, Rolling Stone, People Magazine, Newsweek, Time, Life, After Dark, Vogue, Elle, Harpers Bazaar, Vanity Fair, Madam Figaro, Stern, and virtually every domestic and international publication featuring photographs of arts personalities.
After a forty-five year career in New York City Jack Mitchell and his partner Bob Pavlik now reside, in semi-retirement, in New Smyrna Beach, Florida. Jack works nearly every day producing black and white exhibition prints from his vast negative files and working on the concept and content for a book of his fifty-five years of Dance photography.
I was privileged to have had access to Jack Mitchell's enormous archives and was truly astonished and thrilled by what I saw. In my documentary you will see hundreds of Jack Mitchell photographs, many of which have never before been published or exhibited. As many of the interviewees in the film echo, Jack's body of work is an amazing chronicle of the arts covering a four-decade period. As longtime friend and subject Edward Albee says, "He's a rather extraordinary historian. I guess you could call him a photographer, but he transcends that."
- Craig B. Highberger


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Justice Dept. Apple Lawsuit Drawing Near
A filing could come as early as Wednesday morning as the Justice Department prepares to sue Apple over alleged e-book price-fixing. The DOJ is investigating whether the tech giant cut unfair deals with five publishers—Simon & Schuster Inc., HarperCollins, Hachette Book Group, Pearson, and Macmillan—to inflate the cost of e-books. Under the agreement, the publishers would set the price of the books, and Apple would get a 30 percent cut. The DOJ has been negotiating with publishers, and several are expected to settle this week. Publishers are expected to begin selling their content to other retailers like Amazon and Barnes & Noble at a lower cost.