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App Like Grindr For Straight People Android
Apps Like Grindr For Straight People
The first app on the list that is gaining a lot of attention around the world is Pure. Pure is one of the best apps like Grindr for straight people if you are looking to get right to the point without having to carry much of a conversation with each other.
Top 5 Apps Like Grindr for Straight Guys 2018 List
If you like Grindr and how it is setup, but are looking for an alternative for straight people; Blendr is one of the best options out there. This is an app where you will be able to find like-minded people near you and you will instantly be able to chat with them if they are someone you might be looking for.
Apps Like Grindr Best Apps 2016 5 Apps Like
Badoo is one of the more unique apps like Grindr that you can download for free. This app allows you to connect with people who you have bumped into in real life once before. Whether you are gay or straight, Badoo can provide you with a bunch of guys and girls that could potentially be a great match for you. Badoo lets you see where you have bumped into that person before, what time, and how
Grindr Alternatives and Similar Apps AlternativeTo.net
Popular Alternatives to Grindr for Android, iPhone, iPad, Web, Android Tablet and more. Explore 17 apps like Grindr, all suggested and ranked by the AlternativeTo user community. Explore 17 apps like Grindr, all suggested and ranked by the AlternativeTo user community.
Apps Like Grindr For Straight People Best Grinder
10/09/2016· Here are three apps like Grindr for straight people. These apps can be used to hook up with others, date, or get down, all depending on what you are looking for.
Grindr Wikipedia
Grindr (/ ˈ ɡ r aɪ n d ər /) is a geosocial networking and online dating application geared towards gay, bi, trans, and queer people. It runs on iOS and Android and is available for download from the Apple App Store and Google Play, Grindr comes in both free and subscription-based versions (the latter called Grindr
Grindr Gay chat Apps on Google Play
Grindr is the world's #1 FREE mobile social networking app for gay, bi, trans, and queer people to connect. Chat and meet up with interesting people for free, or upgrade to Grindr XTRA for more features, more fun, and more chances to connect.
Apps Like Tinder: 15 Best Alternative Dating Apps for 2019
Grindr is a dating service which is exactly like Tinder but for gay, bi, trans, and queer people. Since launching in 2009, Grindr has quickly grown into the world's largest social networking app for gay, bi, trans, and queer people.
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30 Apps Like Grindr for Android. 1. Badoo. Badoo is the app for the favorite social networking for dating and meeting new people. Thanks to Badoo you can meet people from across the world that match your likes and requires, and also have the possibility meet up with them for coffee or whatever it
Why isn't there a Grindr for straight people? Life and
My initial hypothesis is that Tinder is the Grindr for straight people. Of the different apps that tried to corner the market circa 2010, Tinder certainly seems to have been the most successful
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The New Grindr for Straight People Will Never Work. After years of hearing their gay friends rave about the mobile, GPS-enabled hook-up app Grindr, straights finally have their own version, released today
Best LGBT Dating Apps for Android and iOS Digital Trends
If you're tired of dating apps that don't include the trans and queer communities, Grindr is a perfect solution. As the largest social networking app for gay, bi, trans, and queer people, you
Five alternative gay apps to use when Grindr stops a
In conclusion, while the outage of Grindr only lasted several hours.. if this becomes a recurring pattern, they have a very good chance of losing people to other apps. They should really look at
Grindr app goes straight The Guardian
Grindr founder Joel Simkhai has received requests from women for a female-friendly, straighter version of the mobile date-finding app. Photograph: Suki Dhanda Grindr is going straight. The mobile
10 Grindr Alternatives & Similar Software Top Best
Grindr is a social network that connects gay and bisexual men who want to meet other men placed near them discreetly and anonymously, without giving personal information or fill out a profile with confidential information to register. This application is based primarily on the exact location of each user, which will facilitate contact between people who are close to their position
grindr App Informers Your Source For iOS, Android
We have some bad news about Dragon Star Varnir, which was supposed to hit Steam in the next couple months. It was just announced...
10 Grindr Alternatives & Similar Software Top Best
Grindr is a social network that connects gay and bisexual men who want to meet other men placed near them discreetly and anonymously, without giving personal information or fill out a profile with confidential information to register. This application is based primarily on the exact location of each user, which will facilitate contact between people who are close to their position
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Grindr for straight people. The project is already underway. Nicknamed Amicus,from the *LATIN meaning friend, the app will offer the same geo-based match-making service to everyone else when it
Gay dating apps: A comprehensive guide to Jack'd, Grindr
Whereas Tinder was once thought of as Grindr for straight people, the ability to set your preferences to find other gays has made Tinder an increasingly popular choice.
Gay dating apps better than grindr Woman How to Find
The grindr on my smartphone, and none of dating app for a straight people. Jack'd: grindr is mostly a gay apps for grindr is the app, the app grindr grant gay dating apps? Kyoto researchers' method is faster, the gay dating apps how long is too long to be dating someone smartphones, trans. I had more discerning on grindr join the gay dating a. Founded in the insecurity that he uses gay
Blendr: The 'boring' Grindr-like hookup app for straight
When Joel Simkhai's female friends spoke jealously of Grindr, a popular GPS-based casual-sex hookup service for gay men, and said they wanted a similar smartphone app for straight people, Simkhai
The best queer dating apps, since meeting people in real
It's unclear whether Chappy will produce longer and more satisfying relationships for me than traditional apps like Grindr. If nothing else, the app at least gives people the illusion that such a
About us Grindr
Since launching in 2009, Grindr has grown into the largest social networking app for gay, bi, trans, and queer people. We have millions of daily users who use our location-based technology in almost every country in every corner of the planet.
Best hookup apps (and sites) for 2019: Here's to keeping
Relationship apps aren't the place to find a hookup — these cut straight to the chase.
13 Best Dating Apps: OK Cupid to Grindr to Sonar
Love Connection 13 Best Dating Apps: OK Cupid to Grindr to Sonar. Where to find love online? Nina Strochlic looks at sites to help you boost your love life in the new year.
Blendr Chat, Flirt & Meet Apps on Google Play
Find nearby dates with Blendr, the free, socially flirtatious chat-to-meet app. Blendr uses your Android's location services to connect you with the fun singles closest to you who share your interests and want to chat it up! With more than 180 million users around the world, Blendr is the best way to break the ice with more people around you.
Download Grindr app on PC with BlueStacks
Grindr app is a game which exemplifies the thought BlueStacks put into developing keyboard controls that feel intuitive and responsive. The default controls that BlueStacks ship with the game have been custom made by gamers like you after days of testing and optimization.
Blendr iPhone App, the Straight Version of Grindr gq
Full disclosure: As it happens, I'm straight. No one's fault. That's just me. But the Grindr team, in September, was launching a new app, Blendr—which was not just for gay guys but for Everybody.
How to Use Grindr on Your Desktop Computer Lifewire
Grindr, the popular social network for gay, bisexual, transgender, and queer people, uses location data from its member's devices to facilitate real-life connections. It's a mobile-first app — meaning that it's optimized for use on mobile devices such as iPhones,iPads,and Android phones and tablets.
Dating app like grindr Haus Hubertus Straberg
An app has changed and dating apps make an app for straight people who like tinder and. Originally launched, how to the sims is a simple block of. Still harboring less than 192 countries, and grindr bots.
Is there a grindr for straight people? : grindr reddit
All posts related to the gay dating app Grindr are welcome. We encourage posts for: Questions, Discussion, Screenshots (Funny and otherwise). Please remember to tag NSFW when necessary.
Gay Dating Apps Other than Grindr Jason Frazer
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Grindr To Launch Straight Version Of App HuffPost
Like the current Grindr app, the new service will locate potential dates in a user's area, based on GPS data from the user's smartphone. Users will also be able to view other members' profiles, photos and stats. But, Simkhai said, a female-oriented service will be more robust.
We need to talk about how Grindr is affecting gay men's
Apps like Grindr, with 3 million daily active users, and others like Scruff and Jack'd, are designed to help gay men solicit sex, often anonymously, online. I am all for sexual liberation, but I
Top 5 Best Gay & Lesbian Dating Apps for iPhone &
Top 5 Best Gay & Lesbian Dating Apps for iPhone & Android Share Catering to straight, gay, and bisexual people, OkCupid is a free dating app that's beloved by online dating fans. Ideal for
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Cowan House
North Somerset
Cowan House
North Somerset
Considering the current climate and the difficulties that everyone is experiencing with the presence of Covid-19, I offer therapy sessions remotely, through phone, as well as online, through Skype, at a reduced cost. Feel free to contact me regarding this.
Over the years we all go through overwhelming life experiences. Usually we seek therapy because we feel challenged by these experiences. Even with the most supportive family and friends we can feel isolated and find it hard to share what is going on for us.
At these times, we might want to see a qualified professional, who is able to listen to us non-judgmentally, provide a safe, confidential place, where we can explore things that are important to us, help us find new avenues of being, and if needed, learn new tools and techniques to enhance our well-being.
I am an HCPC registered and British Psychological Society (BPS) Chartered Counselling Psychologist, Supervisor (Register of the Applied Psychology Practice Supervisors) and fully qualified Mindfulness Teacher.
In individual psychological therapy I work with adults and young people aged 16+. In some circumstances I can see young people who are under 16 years of age. Feel free to contact me regarding this.
I am an integrative practitioner, shaping my practice to clients' needs, bringing together understandings derived from various therapeutic approaches, such as relational psychotherapy, acceptance and commitment therapy, mindfulness-based approaches, cognitive- behavioural therapy and humanistic therapy. I aim to meet clients with respect, authenticity and supportive engagement.
To book an initial discussion over the phone regarding your needs and how I may be able to help, please email or call. I aim to respond to your inquiry within 24 hours.
I have worked with a wide range of people in a variety of circumstances seeking help with low self-esteem, anxiety and panic, stress, depression, abuse, trauma, bereavement, neglect and work-related issues, to name a few. Whatever you are experiencing, we will explore it together, at your own pace, you deciding what and how much to share.
My qualifications
2019 UK College of Mindfulness Meditation, Mindfulness Now Certification Certificate in Mindfulness Teaching
2012- 2018 Professional Doctorate in Counselling Psychology; University of the West of England
2011-2012 Certificate in Counselling Skills; University of the West of England
2010-2011 Cognitive Behavioural Therapy Diploma Level 5; NCFE Cognitive Behavioural Therapy Award; Stonebridge Associated Colleges
2008 – 2009 BPS accredited Master of Education in Psychology of Education; University of Bristol
2005 – 2008 Psychology, B.Sc. (Hon), Babes Bolyai University, Romania
My fees are £75 for a 50 minute face-to-face consultation
Considering the current climate and the difficulties that everyone is experiencing with the presence of Covid-19, I offer therapy sessions remotely, through phone, as well as online, through Skype, at a reduced cost of £65 instead of £75. Feel free to contact me regarding this.
|Online counselling:
|Telephone counselling:
|Face to face counselling:
|Home visits:
|Sign language:
|Other languages:
Daytime and evening appointments available throughout the week.
|Young people
|Online supervision:
|Telephone supervision:


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Spring Reading: Your March Smart Style
This month, we're featuring products that serve your home (and home office) during this unprecedented work-from-home routine.
The Secret to Team Building: Connect with Your Senses
A team pulling together can move mountains. But how do you achieve unity? Here are creative activities that offer team-building experiences using sight, sound, smell, taste and touch.


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Tuesday, April 23, 2019
Antenna TV's Hazel Mother's Day Marathon; Netflix Celebrates Laugh-In's 50th Anniversary
This Mother's Day, Antenna TV, Tribune Broadcasting's multicast entertainment network, is giving moms a day off… and bringing on a maid for a day, Hazel! Relax, kick your feet up and watch someone else do the cooking, cleaning and caring. With 34 episodes, Antenna TV's "Hazel Maid for a Day Mother's Day Marathon" runs from 5am to 10pm ET on Sunday, May 12, 2019.
Hazel regularly airs on Antenna TV weekdays at 11am ET, weekends at 8am ET and Saturdays at 4am ET. Antenna TV, Tribune Broadcasting's multicast network, launched on January 1, 2011 airs in 136 TV markets across the U.S. reaching 89% of TV households, including WPIX-TV (11.2) New York, KTLA-TV (5.2) Los Angeles, and WGN-TV (9.2) Chicago. On January 1, 2016, Antenna TV became the new home of Johnny Carson. For local station information, please visit: http://antennatv.tv/channel-finder/
Netflix's Still Laugh-In: The Stars Celebrate, a 50th anniversary tribute to Rowan & Martin's Laugh-In will launch globally on the streaming service on Tuesday, May 14, 2019. The special, which was taped at Hollywood's Dolby Theater, is filled with an elite lineup of talent paying homage to the iconic show and its director/producer George Schlatter with modern takes on timeless moments, including Lily Tomlin's revival of her seminal Edith Ann and Ernestine characters.
The celebrated lineup of stars include: Lily Tomlin, Ruth Buzzi, Billy Crystal, Snoop Dogg, Tiffany Haddish, Chelsea Handler, Neil Patrick Harris, Taye Diggs, Michael Douglas, Jay Leno, Rita Moreno, Rita Wilson, JoAnne Worley, Maria Bamford, Margaret Cho, Ron Funches, Nikki Glaser, Lisa Ann Walter, Mary McCormack, Bobby Moynihan, Cheri Oteri, Rob Riggle, Jeff Ross, J.B. Smoove, Tony Hale, Jon Lovitz, Natasha Leggero, Kenya Barris, Michael Rapaport, Jameela Jamil and more.
Sitcoms Airing Tonight
Thursday, April 9
Young Sheldon - "A Slump, a Cross and Roadside Gravel" (CBS, 8:00PM ET/PT) (Repeat)
Sheldon and Georgie mine for platinum in roadside gravel. Also, Mary is concerned when Missy misuses religion to help with a batting slump.
Man with a Plan - "Adam's Big Little Lie" (CBS, 8:30PM ET/PT)
Adam promises not to lie to Andi again but finds himself in a tough spot when he has to cover for Joe.
Mom - "Hot Butter and Toxic Narcissism" (CBS, 9:00PM ET/PT) (Repeat)
Christy regrets fleeing the scene after hitting a parked car. Also, Bonnie's therapist, Trevor (Rainn Wilson), offers tools to help her better communicate with Adam.
Broke - "Jobs" (CBS, 9:30PM ET/PT)
When Jackie encourages Javier and Elizabeth to get jobs so they can contribute financially to the household, Javier gets work as a ride share driver, with Luis' help, and Elizabeth is employed as a personal shopper. Also, Jackie worries Sammy will get hurt by becoming so close with his uncle Javier.
Last Man Standing - "Garage Band" (Fox, 8:00PM ET/PT)
A car restoration article throws Mike, Chuck, and Ed into the spotlight, while leaving Joe feeling unappreciated; Ryan overreacts after taking Kyle's psych test.
Last Man Standing - "A Bedtime Story" (Fox, 8:30PM ET/PT) (Repeat)
Mike tries to avoid hurting Vanessa's feelings due to her snoring; Mandy goes overboard preparing for the arrival of Kristin and Ryan's new baby.
Superstore - "" (NBC, 8:00PM ET/PT) (Repeat)
Brooklyn Nine-Nine - "Valloweaster" (NBC, 8:30PM ET/PT)
The squad competes in an effort to determine who is the greatest human/genius.
Will & Grace - "We Love Lucy" (NBC, 9:00PM ET/PT)
Will claims living with Grace is like Ricky living with Lucy. When Karen and Jack hear this, they each claim that they are the Lucy of the group. Grace, Karen, and Jack each imagine themselves as Lucy (during "Vitameatavegamin," "Chocolate Factory," and "Grape-Stomping"), with Will as the Ricky to all of them. Lucie Arnaz and Leslie Jordan guest star.
Indebted - "Everybody's Talking About King and Queens" (NBC, 9:30PM ET/PT)
Debbie decides to become a certified life coach to help her and Stew get out of debt and immediately make waves in Dave and Rebecca's lives. Stew rejects Joanna's help while trying to come up with a great new as-seen-on-TV product.
Better Things - "High Man. Bye Man" (FX, 10:00PM ET/PT)
Sam goes to the weed store and visits her brother; Frankie and Sam eat ice cream.
Sitcom Stars on Talk Shows (Week of April 6)
Thursday, April 9
- Don Cheadle (Black Monday/House of Lies/The Golden Palace) - Catch Don on Jimmy Kimmel Live! at 12:05am on ABC.
- Regina Hall (Black Monday/Grandfathered) - Regina appears on Jimmy Kimmel Live! at 12:05am on ABC. She will also be on Access Daily, so check your local listings.
- Jane Fonda (Grace and Frankie) - Jane is a guest on Late Night with Seth Meyers at 12:36am on NBC.
- Abby Elliott (Indebted/Odd Mom Out) and Adam Pally (Indebted/Making History/The Mindy Project/Happy Endings) - Abby and Adam are guests on A Little Late with Lilly Singh at 1:35am on NBC.
- Tig Notaro (One Mississippi) - Tig will be on Conan at 11pm on TBS.
- Casey Wilson (Marry Me/The Hotwives/Happy Endings) - Casey appears on Watch What Happens: Live at 11pm on Bravo.
- Danielle Schneider (The Hotwives) - Danielle is a guest on Watch What Happens: Live at 11pm on Bravo.
- Victor Rasuk (How to Make It in America) - Victor previews the new series The Baker and the Beauty on LIVE! with Kelly and Ryan, so check your listings.
- David Spade (Rules of Engagement/8 Simple Rules/Just Shoot Me!) - David appears on The Ellen DeGeneres Show, so check your local listings.
- Rob Lowe (The Grinder/Parks and Recreation) - Rob is a guest on The Kelly Clarkson Show, so check your local listings.
- Kim Fields (The Facts of Life/Living Single) - Kim appears on a repeat of Tamron Hall, so check your local listings.
- Christine Baranski (Happy Family/Welcome to New York/Cybill) - Christine will be on CBS This Morning sometime between 7-9am.
- Tim Robbins (The Brink) - Tim is a guest on a repeat of Access Daily, so check your local listings.
- Busy Philipps (Vice Principals/Cougar Town) - Busy appears on a repeat of Access Daily, so check your local listings.
- Daniella Monet (Baby Daddy/Victorious/Listen Up!) - Daniella cooks lentil soup on a repeat of Home & Family on Hallmark Channel at 10am ET/PT.
New on DVD/Blu-ray (January/February/March/April)
01/02 - My Three Sons - The Fifth Season - Volume One
01/02 - My Three Sons - The Fifth Season - Volume Two
01/14 - Veep - The Final (Seventh) Season (Blu-ray)
01/14 - Veep - The Complete Series (DVD)
01/21 - Hangin' with Mr. Cooper - The Complete Third Season (WBShop.com)
01/21 - The Mindy Project - The Complete Series (Blu-ray)
01/28 - Ballers - The Complete Fifth and Final Season
01/28 - Ballers - The Complete Series
01/28 - The Mindy Project - The Complete Series (DVD)
02/04 - Martin - The Complete Series (WBShop.com)
02/11 - Step by Step - The Complete Sixth Season (WBShop.com)
02/18 - Unbreakable Kimmy Schmidt - The Complete Series (Blu-ray)
02/25 - Better Things - The Complete Third Season
03/17 - Crashing - The Complete Third Season (Blu-ray)
04/07 - Cheers - The Complete Series (2020 Release)
04/14 - Police Squad! - The Complete Series (Blu-ray)
04/14 - The Righteous Gemstones - The Complete First Season
04/21 - Step by Step - The Complete Seventh and Final Season (WBShop.com)
More TV DVD Releases / DVD Reviews Archive / SitcomsOnline Digest
Recent SitcomsOnline.com News Blog Posts


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This book reports mostly on institutional arrangements under policy and legal issues, composting and vermicomposting of solid waste under processing aspects, electrical and electronic waste under industrial waste category, application of GIS and LCA in waste management, and there are also several research papers relating to GHG emission from dumpsites.
The chapter discusses common both infectious and non infectious skin diseases in the tropical environment in a medicine text book: Medicine: Non-communicable Diseases in Adults; which widely explores common medical diseases in the tropical setting. The chapter begins with the outline, glossary of terms and introduction to the structure and function of the skin. Skin infections are discussed under bacterial, viral, fungal and parasitic infestations at the end of the section.The section on Allergic or immunological disorders discusses eczema in its diversity, urticaria and adverse cutaneous drug reactions.The last section discusses acne vulgaris and the papulosquamous disorders.
Objective: To describe the characteristics and pattern of maxillofacial and concomitant injuries sustained in Road Traffic Accidents (RTAs).
Study Area: Kenyatta National Hospital (KNH).
Study Design: A descriptive cross sectional study including all patients involved in RTAs
brought to casualty and dental departments of KNH as well as accident victims admitted to the
KNH mortuary over a four- month period from September 2004 to December 2004.
Results: A total of 482 people involved in RTAs were included in the study. Four hundred and
thirteen (85.7%) had non-fatal injuries whereas 69 (14.3%) had sustained fatal injuries.
Nonfatal injuries. The 21-30-year-old age group was the most affected. The male to female ratio
was 4:1. Day time injuries were recorded among 60.3% of the participants. The incidence of
RTAs was highest on Fridays. There were 245 (59.5%) pedestrians and 139 (33.7%) passengers
involved. Most accidents were caused by passenger service vehicles (matatu) which were
responsible for 256 (62%) casualties whereas private saloon cars were involved in 150 (36.3%)
cases. Non- use of safety belts was reported in 90 (56.6%) cases whereas over-speeding was
reported by 120 (29.1 %) casualties. Alcohol use by drivers was reported in 26 (6.3%) cases
whereas vehicle defects accounted for 62 (15%) cases.Three hundred and seventy (89.6%)
casualties had soft tissue injuries (STls) involving the craniofacial region with facial cuts being the
majority (69.2%). Two hundred and seventy three (66.1 %) incidents of other STls than those of
the head region were noted, the lower limbs accounting for 45.4% of these. Only 5.1% of the
casualties had fractures involving the maxillofacial skeleton. Skeletal injuries other than those
involving the maxillofacial region were found in 142 (34.1%) incidents. The lower limbs were
more affected with 61 (43%) incidents followed by the upper limbs (24.6%). Pedestrians were
most involved in sustaining skeletal injuries than other categories of road users.
Fatal RTAs: Sixty nine (14.3%) of the 482 participants were fatally injured. The 21-30- year-old
age group was the most affected (20%). The male to female ratio was 3.3:1. Matatus and minibuses
were the leading cause of fatal accidents together having been responsible for 28 (40.6%) of
the accidents. Pedestrians (71.4%) were by far more involved than other categories of road users.
Most participants had multiple injuries with chest injuries having been the most common (50
cases). Fourty six (66.7%) victims had injuries to the head region with subdural haemorrhage
having been the commonest injury found at autopsy (47.8%). Injuries to the chest were found in
fifty (72.2%) victims whereas abdominal and limb injuries were recorded in 42 (60.9%) and 34
(49.3%) victims respectively. Head injury alone was the leading cause of death (37.7%) followed
by head and chest injuries combined (13.0%)
Conclusion: The majority of people involved in RTAs were in their third decade of life with
males having been the predominant group affected. Pedestrians were the leading casualties
amongst road users. Most of the accidents were caused by passenger service vehicles. The lower
limbs sustained most soft tissue and skeletal injuries compared to other anatomic sites other than
the craniofacial area. The leading cause of death was head injury.
Background: Increasing access to HIV-related health care is very important in access resource limited countries. In Kenya HIV prevalence increased in 2008 to 7.8 from 6.7 in 2003. Women are mostly affected with infection rates 2-3 times more than men. Challenges women face attempting to access HIV care is urgent.Purpose: Study sought to identify health needs of HIV infected women in Kenya grapple with.Method: Forty Urban (Nairobi) and rural (Eastern Province) infected women participated in the study. A cross sectional qualitative narrative study eilicited life stories of health needs. Unstructured in-depth interviews,tape recorded, transcribed and translated to English. Data analysis used N-vivo qualitative analysis soft ware. Multistage narrative analysis was used to explore emergent themes.Findings: Women of mean age 37 years and 3 years since diagnosis described prolonged illnesses sufferred by spouses, themselves and children burdened by inadequate HIV care.Conclusion: Early diagnosis and treatment Interventions are necessary for wellbeing and long life.
{ Abuse of substances of dependence have risen dramatically and spawned major health problems in Kenya. We conducted a study on the effects of post-basic psychiatric training on nurses
In order to increase generation capacity from reliable sources, Kenya has proposed to install a low-end nuclear power plant to supplement the envisaged short fall. At the moment, most of the power is generated from hydro and geothermal sources. Although an expansion of …
This paper builds a case for a reconsideration of Kenya's legislation that relates to cultural and societal heritage resources management by briefly revisiting the circumstances that informed the enactment of the related laws. We present the view that existing legislation has tended to serve corporate, multinational and foreign interests at the expense of local and national interests, and that although these Acts may have somewhat served the country in the past, the legislations have turned the cultural heritage management in Kenya into a lame duck framework of abstractions of policy matters, that are irrelevant and unresponsive to changing local and international circumstances. We highlight contradictions between and within varied Acts, and offer suggestions for remedy that are geared toward the development of a cultural management policy with local ownership and universal compatibility.
Polymer nano-composite was prepared by grafting partially neutralized acrylic acid onto swollen cellulose isolated from water hyacinth in the presence of nano-hydroxyapatite (nano-HA) using N,N-methylene-bis-acrylamide (MBA) as the cross-linker and ammonium persulphate (APS) as the free radical initiator. Water absorption tests showed an increase in swelling ratio of the copolymer with increased nano-HA content to value of 120 g/g at 2.5% w/v above which it declined. FTIR spectrum of nano-composite revealed grafting of the monomer (acrylic acid/ammonium acrylate) onto cellulose and nano-HA. Transmission electron microscopy (TEM) images of nano-HA synthesized in the presence of Triton X-100 (non-ionic surfactant) displayed rod-shaped agglomerates and nano-particle dispersion within the copolymer matrix. Energy dispersive X-ray (EDX) spectra revealed the constituents of nano-composite to be …
Geogenic controls on groundwater quality are often dominant but remain inadequately characterized for many aquifer systems. The volcano-sedimentary aquifer of Kisumu (Kenya) is used widely to provide safe water to the informal settlements and acts as a strategic, supplementary supply to the city during interruptions in service from the main piped water supply network drawing from Lake Victoria. Little is known, however, of the geogenic controls on groundwater quality in the Kisumu aquifer. We characterize the origin and composition of solutes in groundwaters sampled from the Kisumu aquifer using a range of techniques. Classical graphical methods (i.e. Durov, Piper, Schoeller, Stiff and Ternary plots) were used as interpretative tools of the main hydrogeochemical processes whereas principal component analysis (PCA) and hierarchical cluster analysis (HCA) methods were used to assess hydrochemical variations and water types. An agglomeration schedule with five cluster solutions and between-groups linkage method of clustering using the squared Euclidian distance was employed. Variables were standardized to z-scores so that each variable contributed equally to the clusters. The study identifies three main groundwater geochemical signatures in the Kisumu study area: cation exchange (Ca-Na, Ca-Mg) between aqueous and solid phases, the chemistry of recharge water, and groundwater mixing. The concentration of major ions in groundwater varies with geology and also seasonally. The dominant water facies is Na-Ca-HCO3 type; other hydrochemical facies include Ca-Mg-HCO3 and Na-HCO3. Hydrochemical plots suggest that dissolution of carbonates and halite are the other major chemical processes, in addition to cation exchange, that control the groundwater chemistry in the Kisumu aquifer. Hierarchical cluster analysis of the main cations and anions discriminated satisfactorily the various water types in the study area.
We use the 2016 FinAccess Household survey data of 2015 from 8665 households and desktop reviews to examine how perceptions, behaviour, financial literacy and socio-economic characteristics of un(der) banked consumers can shape their dynamics towards credit usage. The challenges and opportunities for the market players are examined using desktop reviews and their role towards an increase in financial inclusion and credit usage through FinTech. The disruptive innovations have provided new possibilities, challenges and opportunities to boost financial and credit usage in the market. Consumer perceptions on cost, trust, source of financial advice, financial literacy and socio-economic characteristics influences credit usage. The business models being developed by the FinTech providers are taunted to change the landscape of lending to the un(der) banked
There is a gradual paradox shift from the utilization of surface water to groundwater in both urban and rural Kenya. This is because surface water is both diminishing in quantity due to climate variability and deteriorating in quality due to high levels of anthropogenic contamination. In the quest to attain the Sustainable Development Goal number 6 that aim at ensuring access to safe water by all by 2030, the Government of Kenya is encouraging the development of groundwater resources whose potential is enormous though it has not been quantified. The Inter-governmental Authority on Development (IGAD) supported this research on the shared Mt. Elgon trans-boundary aquifer between Kenya and Uganda aimed at understanding its dynamics. Mt. Elgon is a Tertiary age mountain that straddles the Kenya-Uganda border and has a trans-boundary aquifer. This study investigated the groundwater chemistry and its implication on water management and human health. Physico-chemical parameters of water that included electrical conductivity, pH, and temperature were measured in the field and the major cations and anions were measured at the Central Laboratories of the State Department for Water. Geological mapping and identification of sanitary risks were undertaken during the field work. The study revealed that the concentration of cations and anions in the groundwater varied spatially and temporally. Abundance of these ions were in the order Ca²⁺ > Na⁺ > Mg²⁺ > K⁺ for most samples and HCO₃⁻ > Cl⁻ > SO₄²⁻ >NO₃⁻. Interpretation of hydro-chemical data suggests that calcium carbonate dissolution, halite dissolution, Ca/Na ion exchange and Mg/Na ion exchange are the major processes that control the ground-water chemistry. Chemical results indicate further that the groundwater is suitable for domestic use but is threatened by both anthropogenic and geological factors. Extensive use of fertilizer and the destruction of the catchment area coupled with low permeability and rock-water interactions in the metamorphic rock terrains are the main threats to groundwater quality in the region. A few water points had water with some ionic composition exceeding WHO and the local KEBS maximum limits for drinking water. Such water pose a risk to human health.
Tropical montane forests are amongst the most threatened ecosystems by climate change. However, little is known about climatic changes already observed in these montane areas in Africa, or the adaptation strategies used by pastoralist communities. This article, focused on three mountains in northern Kenya, aims to fill these knowledge gaps. Focus-group discussions with village elders were organized in 10 villages on each mountain (n = 30). Villages covered different pastoralist ethnic groups. Historical data on rainfall, temperature and fog were gathered from Marsabit Meteorological station. All participants reported changes in the amount and distribution of rainfall, fog, temperature and wind for the past 20–30 years; regardless of the mountain or ethnicity. They particularly highlighted the reduction in fog. Meteorological evidence on rainfall, temperature and fog agreed with local perceptions; particularly important was a 60% reduction in hours of fog per year since 1981. Starting farming and shifting to camel herding were the adaptive strategies most commonly mentioned. Some adaptive strategies were only mentioned in one mountain or by one ethnic group (e.g. starting the cultivation of khat). We highlight the potential use of local communities' perceptions to complement climatic records in data-deficient areas, such as many tropical mountains, and emphasize the need for more research focused on the adaptation strategies used by pastoralists.
Based on a five-town case-study cohort in Kenya, a conceptual framework has been developed to enable the formulation of holistic and effective strategies that encompass the national aspirations and regional to global sustainability agendas, and which can be used to monitor progress in achieving set objectives. The approach is flexible, scalable and transferrable, so that it can be applied in different contexts and using different indicators, based upon the same construct. Insufficient technical knowledge of urban aquifers and their interplay with the wider social-ecological system constrains the development of holistic, effective and robust management systems to ensure their sustainability for intended uses. The objective was to consider governance and management solutions that could promote water security for urban towns in Kenya through the sustainable use of groundwater in the context of its complex hydrogeology, water access disparities, competing uses and future risks. The in force national and county water policies, strategies, and plans for the case study areas were critically reviewed. The status of aquifer knowledge, water access disparities, competing uses, and risks was evaluated from critical literature reviews and data compilation, fieldwork, and analysis of indicator datasets from the Kenya 2009 census. Key aquifers need urgent characterisation to reverse the current situation whereby development proceeds with insufficient aquifer knowledge. Private sector and public participation in management should be enhanced through decentralised management approaches. Water infrastructure and technologies should be fit-for-purpose in application and scale, and the pro-poor focus should be underpinned by appropriately focused management regimes.
This article investigates a stochastic filtering problem whereby the bor-rower's hidden credit quality is estimated using ego-network signals. The hidden credit quality process is modeled as a mean reverting Ornstein-Ulehnbeck process. The lender observes the borrower's behavior modeled as a continuous time diffusion process. The drift of the diffusion process is driven by the hidden credit quality. At discrete fixed times, the lender gets ego-network signals from the borrower and the borrower's direct friends. The observation filtration thus contains continuous time borrower data augmented with discrete time ego-network signals. Combining the continuous time observation data and ego-network information, we derive filter equations for the hidden process and the properties of the conditional variance. Further, we study the asymptotic properties of the conditional variance when the frequency of arrival of ego-network signals is increased.
Cancer constitutes a major hurdle worldwide and its treatment mainly relies on chemotherapy.
The present study was designed to evaluate the cytotoxicity of eleven naturally occurring compounds including six phenolics amongst them were 4 chalcones and 2 flavanones as well as 5 terpenoids (3 clerodane and 2 trachylobane diterpenoids) against 6 human carcinoma cell lines and normal CRL2120 fibroblasts.
Materials and methods
The neutral red uptake (NR) assay was used to evaluate the cytotoxicity of the compounds, whilst caspase-Glo assay was used to detect caspase activation. Cell cycle and mitochondrial membrane potential (MMP) were all analyzed via flow cytometry meanwhile levels of reactive oxygen species (ROS) was measured by spectrophotometry.
Chalcones: 2′,4′-dihydroxy-6′-methoxychalcone (1); 4′,6′-dihydroxy-2′,5′-dimethoxychalcone (2); 2′,4 …
In our continuous search for cytotoxic compounds from the genus Zanthoxylum, chromatographic separation of the MeOH/CH2Cl2 (1:1) extract of Z. chalybeum yielded one new alkamide; 4-(isoprenyloxy)-3-methoxy-3,4-deoxymethylenedioxyfagaramide (1) and a known one; fagaramide (2). Similarly, from the MeOH/CH2Cl2 (1:1) extract of the stem bark of Z. parachanthum four known compounds; canthin-6-one (3), dihydrochelerythrine (4), lupeol (5) and sesamin (6) were isolated. Characterization of the structures of these compounds was achieved using spectroscopic techniques (NMR and MS). Using resazurin reduction assay 1, 3 and 6 displayed moderate cytotoxicity with IC50 values below 50 μM against the drug sensitive CCRF-CEM and multidrug-resistant CEM/ADR5000 leukemia cell lines. It is interesting to note that 3 was more active than the standard drug, doxorubicin against CEM/ADR5000 leukemia.
In our continuous search for cytotoxic compounds from the genus Zanthoxylum, chromatographic separation of the MeOH/CH2Cl2 (1:1) extract of Z. chalybeum yielded one new alkamide; 4-(isoprenyloxy)-3-methoxy-3,4-deoxymethylenedioxyfagaramide (1) and a known one; fagaramide (2). Similarly, from the MeOH/CH2Cl2 (1:1) extract of the stem bark of Z. parachanthum four known compounds; canthin-6-one (3), dihydrochelerythrine (4), lupeol (5) and sesamin (6) were isolated. Characterization of the structures of these compounds was achieved using spectroscopic techniques (NMR and MS). Using resazurin reduction assay 1, 3 and 6 displayed moderate cytotoxicity with IC50 values below 50 μM against the drug sensitive CCRF-CEM and multidrug-resistant CEM/ADR5000 leukemia cell lines. It is interesting to note that 3 was more active than the standard drug, doxorubicin against CEM/ADR5000 leukemia …
While incidences of cancer are continuously increasing, drug resistance of malignant cells is observed towards almost all pharmaceuticals. Several isoflavonoids and flavonoids are known for their cytotoxicity towards various cancer cells.
The first phytochemical investigation of the flowers of Millettia dura resulted in the isolation of seven isoflavones, a flavonol and a chalcone. Eleven isoflavones and a flavonol isolated from various plant parts from this plant were tested for cytotoxicity against a panel of cell lines, and six of these showed good activity with IC50 values of 6-14 μM. Durmillone was the most active with IC50 values of 6.6 μM against A549 adenocarcinomic human alveolar basal epithelial cancer cell line with low cytotoxicity against the non-cancerous cell lines BEAS-2B (IC50 = 58.4 μM), LO2 hepatocytes (IC50 78.7 μM) and CCD19Lu fibroblasts (IC50 >100 μM).
Keywords: Millettia dura, Leguminosae, isoflavone, cytotoxicity.
Cancer constitutes a major hurdle worldwide and its treatment mainly relies on chemotherapy.
The present study was designed to evaluate the cytotoxicity of eleven naturally occurring compounds including six phenolics amongst them were 4 chalcones and 2 flavanones as well as 5 terpenoids (3 clerodane and 2 trachylobane diterpenoids) against 6 human carcinoma cell lines and normal CRL2120 fibroblasts.
Materials and methods
The neutral red uptake (NR) assay was used to evaluate the cytotoxicity of the compounds, whilst caspase-Glo assay was used to detect caspase activation. Cell cycle and mitochondrial membrane potential (MMP) were all analyzed via flow cytometry meanwhile levels of reactive oxygen species (ROS) was measured by spectrophotometry.
Chalcones: 2′,4′-dihydroxy-6′-methoxychalcone (1); 4′,6′-dihydroxy-2′,5′-dimethoxychalcone (2); 2′,4 …
Scholar articles
Cytotoxicity of naturally occurring phenolics and terpenoids from Kenyan flora towards human carcinoma cells
V Kuete, LK Omosa, JO Midiwo, O Karaosmanoğlu… - Journal of Ayurveda and integrative medicine, 2019
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Male circumcision provides men with approximately 60% protection from acquiring HIV infection via heterosexual sex, and has become a key component of HIV prevention efforts in sub-Saharan Africa. Possible mechanisms for this protection include removal of the inflammatory anaerobic sub-preputial environment and the high concentration of Langerhans cells on the inside of the foreskin, both believed to promote local vulnerability to HIV infection. In people who do acquire HIV, viral load is partially determined by infecting partner viral load, potentially mediated by size of infecting inoculum. By removing a portal for virion entry, prior male circumcision could decrease infecting inoculum and thus viral load in men who become HIV-infected, conferring the known associated benefits of slower progression to disease and decreased infectiousness.
The prevalence of non-communicable diseases (NCDs) is rising in low- and middle-income countries, including Kenya, disproportionately to the rest of the world. Our objective was to quantify patient payments to obtain NCD screening, diagnosis, and treatment services in the public and private sector in Kenya and evaluate patients' ability to pay for the services.
Diarrhoea is a major cause of child mortality. Although oral rehydration solution (ORS) is an efficacious intervention for correcting dehydration, inadequate monitoring may limit its effectiveness in routine settings. We evaluated the effect of using a caregiver-administered chart to monitor oral fluid therapy on hydration status among children with some dehydration.
Potato (Solanum tuberosum L.) synthesizes a variety of bioactive metabolites including phenolic compounds and glycoalkaloids that protects against insects and diseases, and may influence its nutritional quality. Phenolics provide valuable health promoting antioxidants, whereas glycoalkaloid concentrations exceeding the upper safety limit of 20 mg/100 g fresh weight (Fwt) are potential neurotoxins. Therefore, efficient selection for tuber nutritional quality is dependent upon safe and reliable analytical methods. The aim of this study was to determine the changes in the concentration of glycoalkaloids and phenolic compounds during different growth stages in tubers of five selected potato varieties grown in Kenya. α-chaconine and α-solanine were separated and identified by HPLC. Total glycoalkaloids (TGA) and phenolics were determined by UV spectrophotometry. Recovery efficiencies for validation of analytical methods ranged from 85.9-93.5%. Significant differences in TGA and phenolic contents were detected among potato varieties. Tuber TGA content ranged from 6.80 to 10.56 mg/100g Fwt in vars. Dutch Robijn and Tigoni, respectively, and were within the upper safety limit. The corresponding values for chlorogenic acid contents in the examined varieties ranged from 46.39 to 58.04 mg/100 g Fwt. Total phenolic concentration in the examined tuber extracts varied ranged from 129.24 to 192.52 mg CGA/g Fwt. Glycoalkaloid and phenolic production were significantly reduced from time of initiation to maturity at 55 and 125 days, respectively, after planting (DAP). These results demonstrate that tuber phytochemicals were strongly influenced by variety and level of maturity. For nutritional safety and quality purposes, harvesting of mature potato tubers after 125 DAP is recommended
Somalia has faced severe challenges linked to climate variability, which has been exacerbated by conflict and limited governance that persisted for decades. Today climate extremes such as floods, drought, and coastal marine severe systems among others are always associated with the destruction of property and livelihoods; losses of lives lost, migrations, and resource based conflicts among many other miseries. Intergovernmental Panel on Climate Change (IPCC) has shown that climate change is real and requires sound knowledge of local future climate change scenarios. The study attempted to provide projected rainfall and temperature change scenarios over Lower Jubba, Somalia. This was done using the downscaled Coordinated Regional Downscaling Experiment (CORDEX) RCMs data. The simulated temperature and rainfall data derived from the CORDEX RCMs ensemble were compared with the observed data. The study focused on the IPCC projected periods of
2030, 2050 and 2070 benchmarks. Analysis of the projected rainfall indicated a decreasing trend in rainfall leading up to 2030 followed by an increase in rainfall with the 2050 and 2070 scenarios. In the case of temperature, the projections from all the models showed increase in minimum and maximum temperatures in all seasons and sub periods, like being observed by temperature projection over other parts of the world. The 2030, 2050 and 2070 projected rainfall and temperature change scenarios show that Somalia future development and livelihoods will in future face increased threats of climate extremes unless effective climate smart adaptation systems form integral components of national development strategies.
The co-evolution and co-movement of financial time series are of utmost importance in contemporary finance, especially when considering the joint behaviour of asset price realizations. The ability to model interdependencies and volatility spill-over effects introduces interesting dimensions in finance. This paper explores co-integrating relationships between crude oil and distillate fuel prices. Existence of multivariate co-integrating relations and bidirectional Granger-Causality is established among the series. It is also established that even after fitting a full VECM, the residuals are not necessarily multivariate normal suggesting the noise could as well be multivariate GARCH.
Chalcogenide system of antimony (Sb)-selenium (Se)-zinc (Zn) system is a promising semiconductor for phase change memory devices due to its thermal stability and low power consumption. The study investigated the effect of film thickness and zinc content on the optical properties of thermally evaporated Sb10Se90-xZnx (x = 0, 5, 10 & 15 at. %) thin films. It was found that transmittance (T~ 85-40%) and optical band gap energy (Eopt ~ 1.60 eV – 1.22 eV) decreased but absorption coefficient (α~0.840–2.031 104 cm–1) increased with increase in zinc content. Furthermore, as the film thickness increased from 53 ± 5 nm to 286 ± 10 nm, transmittance decreased but band gap energy increased due to zinc defects and localized states in the Sb10Se90-xZnx system.
The need for clean and safe consumable water is of paramount importance to any society since water is a crucial substance for the sustenance of life. Kibera slum is one of the leading slums in the world with a high population, leading to poor levels of sanitation and inadequate clean water supply. Consequently, the residents have to seek for alternative water supply. Motoine River flows through the slum, and thus acts as an alternative source of water. This study determined the concentration levels of heavy metals (Pb, Fe, Cu, Cr and Cd) and nutrients (nitrates, nitrites and phosphates) in Motoine River, Kibera in September 2014 and compared the variations downstream. The metals were determined using Atomic Absorption Spectroscopy (AAS) while the nutrients were determined using UV/Visible spectroscopy. Concentration levels of Cu, Cd and Cr were found to be lower than the Environmental Protection Agency (EPA) values for maximum contaminant level (MCL) while those of Fe, Pb and the nutrients were higher than EPA's MCL values. Cd had the lowest concentration and was below the detection limit of the instrument used. Nitrates were found to be of the highest concentration at 16.4959 ± 2.4432 parts per million (ppm). The high concentration of nutrients in the water could be due to domestic waste and effluent disposal into the river and agricultural runoffs while that of metal ions could be due to waste from informal jua kali industries and erosion of natural deposits. The efforts by the government to rehabilitate and clean rivers within Nairobi should be extended to include Motoine River.
A phytochemical investigation of the roots of Aspilia pluriseta led to the isolation of ent-kaurane-type diterpenoids and additional phytochemicals (1–23). The structures of the isolated compounds were elucidated based on Nuclear Magnetic Resonance (NMR) spectroscopic and mass spectrometric analyses. The absolute configurations of seven of the ent-kaurane-type diterpenoids (3–6, 6b, 7 and 8) were determined by single crystal X-ray diffraction studies. Eleven of the compounds were also isolated from the roots and the aerial parts of Aspilia mossambicensis. The literature NMR assignments for compounds 1 and 5 were revised. In a cytotoxicity assay, 12α-methoxy-ent-kaur-9 (11), 16-dien-19-oic acid (1)(IC 50= 27.3±1.9 µM) and 9β-hydroxy-15α-angeloyloxy-ent-kaur-16-en-19-oic acid (3)(IC 50= 24.7±2.8 µM) were the most cytotoxic against the hepatocellular carcinoma (Hep-G2) cell line, while 15α-angeloyloxy-16β, 17-epoxy-ent-kauran-19-oic acid (5)(IC 50= 30.7±1.7 µM) was the most cytotoxic against adenocarcinomic human alveolar basal epithelial (A549) cells.
Chromatographic separation of the extract of the roots of Dorstenia kameruniana (family Moraceae) led to the isolation of three new benzylbenzofuran derivatives, 2-(p-hydroxybenzyl)benzofuran-6-ol (1), 2-(p-hydroxybenzyl)-7-methoxybenzofuran-6-ol (2) and 2-(p-hydroxy)-3-(3-methylbut-2-en-1-yl)benzyl)benzofuran-6-ol(3) (named dorsmerunin A, B and C, respectively), along with the known furanocoumarin, bergapten (4). The twigs of Dorstenia kameruniana also produced compounds 1–4 as well as the known chalcone licoagrochalcone A (5). The structures were elucidated by NMR spectroscopy and mass spectrometry. The isolated compounds displayed cytotoxicity against the sensitive CCRF-CEM and multidrug-resistant CEM/ADR5000 leukemia cells, where compounds 4 and 5 had the highest activities (IC50 values of 7.17 μM and 5.16 μM, respectively) against CCRF-CEM leukemia cells. Compound 5
We report on application of conductive silver paste smeared glass slides as Raman spectroscopy sample substrates for label-free detection of HIV-1 p24 antigen in blood plasma. We also show that the same substrates can be applied in Raman spectroscopic screening of blood plasma for presence of HIV. The characteristic Raman spectrum of HIV-1 p24 antigen displayed prominent bands that were assigned to ribonucleic acids (RNA) and proteins that constitute the antigen. This spectrum can be used as reference during Raman spectroscopic screening for HIV in plasma within the first few days after exposure (<7 days). The Raman spectra obtained from HIV+ plasma displayed unique peaks centered at wavenumbers 928, 990, 1270, 1397, and 1446 cm(-1) attributed to the Raman active vibrations in the virion carbohydrates, lipids, and proteins. Other bands similar to those reported in literature were also seen and assignments made. The attachment of the HIV virions to silver nanoparticles via gp120 glycoprotein knobs was thought to be responsible for the enhanced Raman signals of proteins associated with the virus. The principal component analysis (PCA) applied on the combined spectral data showed that HIV- and HIV+ spectra had differing spectral patterns. This indicated the great power of Raman spectroscopy in HIV detection when plasma samples are deposited onto silver paste smeared glass substrates. The Raman peaks responsible for the segregation of the spectral data in PCA were mainly those assigned to the viral proteins (645, 725, 813, 1270, and 1658 cm(-1)). Excellent results were obtained from Artificial Neural Network (ANN) applied on the HIV+ Raman spectral data around the prominent peak centered at 1270 cm(-1) with R (coefficient of correlation) and R (2) (coefficient of determination) values of 0.9958 and 0.9895, respectively. The method has the potential of being used as quick blood screening for HIV before blood transfusion with the Raman peaks assigned to the virion proteins acting as reference. Graphical Abstract The HIV type 1 virus particle gets attached to the silver nanoparticle contained in the conductive silver paste smear onto a glass slide. This results in strong Raman signals associated with the components of the virion. The signals are collected, dispersed in a spectrometer and displayed on a computer screen. Method can be used as a label-free and rapid HIV screening in blood plasma.
HIV-1 superinfection, in which an infected individual acquires a second HIV-1 infection from a different partner, is one of the only settings in which HIV acquisition occurs in the context of a pre-existing immune response to natural HIV infection. There is evidence that initial infection provides some protection from superinfection, particularly after 6months of initial infection, when development of broad immunity occurs. Comparison of the immune response of superinfected individuals at the time of superinfection acquisition to that of individuals who remain singly infected despite continued exposure can shed light on immune correlates of HIV acquisition to inform prophylactic vaccine design. We evaluated a panel of humoral immune responses in the largest published group of superinfected individuals (n=21), compared to a set of 3:1 matched singly infected controls from the same cohort. The immune functions studied included plasma neutralization, plasma and cervical antibody-dependent cellular cytotoxicity, and plasma IgG and IgA binding to a panel of 18 envelope antigens, including correlates of HIV acquisition in the RV144 vaccine trial, IgG binding to V1V2 and IgA binding to gp140. Association between each immune function and HIV superinfection was evaluated using conditional logistic regression. No significant associations were detected between any of the immune functions and superinfection acquisition. This study constitutes the most comprehensive and detailed characterization of multiple immune correlates of superinfection to date. The results suggest that immune responses not commonly measured in current HIV studies may be important in protection from HIV infection, and these or a more robust humoral response than that seen in naturally infected women may be needed for a protective vaccine.
Gladiolus is a genus that consists of underground corms and strikingly showy flowers. The corms are mostly rounded and symmetrical enveloped with fibrous tunics. Presently the main and sure way to identify these plants is by their use of showy flowers; however, this becomes a challenge in during the dry seasons when the plants don't flower. This study investigated the use of corms as additional feature for identification of Gladiolus species found in Kenya; Gladiolus watsonoides, G. goetzenii, G. ukambanensis and G. newii. Physical and histological features of the corms were evaluated according to Rolls, 2011, to investigate any differences across the different species. Although the analysis of the cells of corms did not reveal any obvious differences, their outward morphologies including the colour, shape and texture of the tunics were different across the species investigated. Therefore, corms form an additional feature of taxonomic value for identification and collection of these plants in the absence of flowers.
Key words: Gladiolus, Corms, Identification
Background: Effective control of malaria requires knowledge of vector species, their feeding and resting behaviour as well as breeding habitats. The objective of this study was to determine malaria vector species abundance and identify their larval habitats in Huye district, southern Rwanda.
Methods: Adult mosquitoes were collected indoors using light trap and pyrethrum spray catch techniques, and outdoors using light traps. Female Anopheles mosquitoes were identified to species level by morphological characteristics. Enzyme-linked Immunosorbent Assay (ELISA) was used to screen for Plasmodium falciparum circumsporozoite protein and host blood meal sources. Anopheles larvae were sampled using dippers and raised into adult mosquitoes which were identified morphologically.
Results: Anopheles gambiae sensu lato comprised of 70% of the 567 Anopheles collected. Other Anopheles species identified were An. funestus 4%, An. squamosus 16.5%, An. maculipalpis 6.5%, An. ziemanni 1.7%, An. pharoensis 1.2 % and An. coustani 0.1%. The majority, 63.5% of the collected mosquitoes were from indoors collections. The overall human blood index was 0.509. The P. falciparum circumsporozoite protein was found in 11 mosquitos including 8 Anopheles gambiae s.l. and 3 secondary vectors out of the 567 tested. The overall sporozoite rate was 1.9%. A total of 661 Anopheline larvae from 22 larval habitats were collected. They comprised of An. gambiae s.l. (89%) and An. ziemanni (11%). The absolute breeding index was 86.4%. The most common larval habitats were in full sunlight with still water like rice paddies and pools of stagnant water.
Conclusion: These findings show that Anopheles gambiae s.l. is the dominant malaria vector in the area with other vectors playing a secondary role in malaria transmission. Malaria interventions need to be strengthened to reduce even further the malaria transmission in the area.
Objectives: Iron deficiency anaemia causes adverse pregnancy outcome. There are few studies on effects of anaemia on the
structure of trophoblastic cells which are important in placental function. These data are important for understanding the
function and disorders of the placenta. The aim of this study was to investigate the ultrastructural cellular changes associated
with iron deficiency anaemia in rat placenta.
Methods: Forty-nine female Sprague-Dawley rats were randomly separated into experimental and control groups. The
experimental group was rendered anaemic by removing 1.5 ml of blood per bleed on five alternate days, and the placentas
were collected on gestational days 17, 19 and 21. For light microscopy, five cubic millimeter segments were fixed in 10%
buffered formaldehyde solution; dehydrated in ethanol and embedded in paraffin wax. Five micron thick sections were cut,
deparaffinized and stained with Hematoxylin and Eosin. For transmission electron microscopy, 1 mm3 sections were fixed in
2.5% phosphate buffered glutaraldehyde, post fixed in 2% osmium tetroxide, dehydrated in ethanol, cleared in propylene
and embedded in epon resin. Ultrathin sections stained with uranyl acetate and lead citrate were examined with JEOL electron
Results: Cytotrophoblast, syncytiotrophoblast and giant trophoblastic cells of placentas of anaemic rats showed cytoplasmic
and nuclear vacuolation with loss of cell margins. In addition, there was atrophy of microvilli on the cell surface, as well
nuclear chromatolysis, nucleolar degeneration and appearance of dark bodies.
Conclusion: Chronic anaemia causes trophoblastic cell degeneration. This may undermine the functional integrity of the
cells and constitute part of the mechanism for poor fetal outcome.
Tsavorite is exclusively hosted in the Neoproterozoic Metamorphic Mozambique Belt (NMMB). The gemstone mines, widespread between Kalalani (Tanzania) and Mgama Ridge (Kenya), define a continuous corridor over a hundred kilometers in length. The tsavorite is hosted by a metasedimentary sequence defined as the Kurase tsavorite-bearing metasediments (Kurase-TB metasediments) that also hosts rubies. These metasediments underwent amphibolite-facies metamorphism and are surrounded by granulitic gneisses that are also of sedimentary origin (the Kurase high-temperature gneisses). All these rocks lie below the Kasigau Group, a unit dominated by granulite-facies metamagmatic rocks.
To constrain the timing of events that led to this peculiar occurrence of tsavorite, we have performed geochronological analyses of thin sections and of separated grains of zircon, monazite, and rutile using LA-ICP-MS and ID-TIMS, as well as 40Ar/39Ar of muscovite and phlogopite from various lithologies. The results show that the different terranes were metamorphosed synchronously between 620–580 Ma but under different P-T strain conditions. The Kurase-HT gneisses and the rocks from the Kasigau Group are highly strained and underwent granulite-facies metamorphism with abundant partial melting and emplacement of felsic melts between 620 and 600 Ma. Textural observations also underlined a late regional water flux controlling the occurrence of V-free muscovite and monazite mineralizations at 585 Ma. The latter event can be related to the activity of the Galana shear zone, in the east. The Kurase-TB metasediments escaped strain and partial melting. They record amphibolite-facies conditions with static heating, since initial sedimentary structures were locally preserved. The age of the tsavorite mineralization was inferred at 600 Ma from metamorphic zircon rims and monazite from the closest host-rocks, sampled in the mines. Hence, tsavorite crystallization occurred statically at the end of the metamorphic event, probably when the temperature and the amount of volatiles were at maximum levels.
Conversely, the ruby formed by local metasomatism of felsic dikes and isolated ultramafic bodies. The rubies are older and zircons and monazites from a ruby-bearing felsic dike (plumasite) were dated at 615 Ma. Finally, data from rutile and micas indicate a global cooling below 430 °C of the whole region between 510 and 500 Ma.
Conversely, the ruby formed by local metasomatism of felsic dikes and isolated ultramafic bodies. The rubies are older and zircons and monazites from a ruby-bearing felsic dike (plumasite) were dated at 615 Ma. Finally, data from rutile and micas indicate a global cooling below 430°C of the whole region between 510 and 500 Ma.
All persons living with Diabetes Mellitus (DM) have a lifetime risk of developing Diabetic Retinopathy (DR), a
potentially blinding microvascular complication of DM. The risk increases with the duration of diabetes. The
onset and progression of DR can be delayed through optimization of control of blood glucose, blood pressure and lipids. The risk of blindness from DR can be reduced through cost-effective interventions such as screening for DR and treatment of sight-threatening DR with laser photocoagulation and anti-VEGF medications.
Several factors make it important to provide guidance to clinicians who provide services for diabetes and
diabetic retinopathy in Kenya. First, the magnitude of both DM and DR is expected to increase over the next
decade. Secondly, as the retina is easily accessible for examination, the early signs of retinopathy may provide clinicians with the best evidence of microvascular damage from diabetes. This information can be used to guide subsequent management of both DM and DR. Thirdly, there are notable gaps in service delivery for the detection,treatment and follow-up of patients with DR, and the services are inequitable. Strengthening of service delivery will require close collaboration between diabetes services and eye care services.
Following a systematic and collaborative process of guideline development, the first published national
guidelines for the management of diabetic retinopathy have been developed. The purpose of this paper is to
highlight the recommendations in the guidelines, and to facilitate their adoption and implementation.
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What are good virtual worlds for kids?
Club Penguin is a very safe virtual game.
Fantage is an educational and fun virtual game.
Tots is for more of a younger age but can be played by older kids.
is a safe and fun virtual world. (This virtual world involves killing evil cogs what are robots).
Barbie Girlz is a girls virtual world.
If doesn't, try typing kids virtual worlds in to Google.
I recomened xivio its very safe.You can get banned for swearing and other bad behavior.I think the age groups are 8-13 so lots of age groups avaible 6 and 7 year olds are welcome but there is somethings they might not understand.
Related Questions
Asked in Internet, Social Network Websites, Club Penguin
Are virtual worlds bad for kids?
Virtual worlds are NOT bad for kids! The people that interact with your child are probably bad. Some are good, some are bad, but virtual worlds are not bad! Virtual worlds are created by people that want your children, teenagers, and adults to have fun when they are bored, or at any time! Their are many virtual worlds, so don't worry about not finding the one that fits you! Good luck! :) - Sally


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Starting at: Canning Town
Arrive at: Mill Hill Broadway
Journey time between Canning Town and Mill Hill Broadway averages at 63 minutes
Stations passed through from Canning Town
- North Greenwich
- Canary Wharf
- Canada Water
- Bermondsey
- London Bridge
- Southwark
- Waterloo
- Westminster
- Green Park
- Bond Street
- Baker Street
- St. John's Wood
- Swiss Cottage
- Finchley Road
- West Hampstead
- Kilburn
- Willesden Green
- Dollis Hill
- Neasden
- Wembley Park
- Kingsbury
- Queensbury
Local disruptions
CANNING TOWN STATION: The busiest time at this station is 05:45-07:30 and 16:00-17:30. Only travel if your journey is absolutely essential.
CANNING TOWN STATION: Please enter the station via Silvertown Way and exit the station via the bus station.
Canning Town: No Step Free Access - Step free access is not available to the Jubilee line and the DLR (high level platforms) due to a faulty lift. Call our Travel Information Centre on 0343 222 1234 if you need help planning your journey.
Ticket price information
Fares between two stations may vary depending on the direction of travel, time of day and day of the week.
We charge higher fares at the busiest times of the day (usually between 06:30 and 09:30, and between 16:00 and 19:00, Monday to Friday).
When you pay as you go, you must touch your contactless or Oyster card on a yellow reader at the start and end of your journey.
Some journeys are charged via Zone 1 regardless of the route taken.
If your journey avoids Zone 1 and you see a pink card reader when changing trains, touch your contactless or Oyster card on it to pay the right fare.
Return journey: Mill Hill Broadway to Canning Town
Note, the results are provided by TfL Open Data, but you should check before travelling in case of disruptions.
Latest journey planner searches
- Canning Town to Hounslow East
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- Canning Town to Langdon Park DLR
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Florida Negotiators Closing In On Gambling Deal
27th Apr 2017 | Written by: Tony Batt
After almost a decade of futility, the Florida legislature is closer than ever to a landmark agreement to comprehensively reform laws regulating the state's unusually complex gambling industry.
Negotiators from the Florida House of Representatives, which passed a bill earlier this year to freeze gambling operations, agreed on Wednesday to make major concessions to their counterparts in the Senate who want to expand gambling.
Among other things, House negotiators agreed to:
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Two weeks have gone by since the Goods and Services Tax (GST) came into force. Yet, confusion and doubts still persist. Small and medium enterprises (SMEs), exporters and traders alike are still struck by a sense of uncertainty, and are hesitant to make their first purchases or raise the first sales invoice.
The Indian arm of Danish major Danfoss, which used to receive 25% of its monthly orders in the first week of every month, had secured orders only for 5% of the monthly average in the first week of July. Lynk Logistics, a Ramco Cements group company, which saw a huge surge in its bookings in the last week of June, is witnessing a dip in its order book.
Members of the Madras Electrical Trades Association have forewarned about a 10% increase in the sale prices, though there has been a marginal decrease in tax rate. An upset Sivakasi Firework Association went on strike to protest against exorbitant GST tax rates. It was, however, a different matter that they withdrew the strike subsequently. Chennai-based Sivanandha Pipe Fittings, which does exports and deemed exports, has been facing short-term liquidity crisis as close to 20% of its working capital is locked in inventory.
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Regretfully, all Masses have been suspended until further notice. Please refer to the letter issued by the Catholic Bishops of Victoria (dd 18th March 2020) under our News section.
The Parish Office will continue to operate, however in line with the social distancing recommendation, we would prefer that you call or email your inquiries where possible.
Sunday's Reading, Mass Intentions & liturgy activity sheets for children & teenagers are posted on the News section.
You can join in the celebration of Mass online using one of the following links:
Facebook: www.facebook.com/stthomasap (Live at 9.00am on Sunday)


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I'm heading out on vacation for two weeks in Jolly Old England. During that time I won't be blogging. If big entertainment news breaks, I'll just have to wait to write something smart about it when I get home.
In the meantime, check out the blogs of some of my very talented colleagues:
Jeff Bercovici is the smartest person writing about the media today.
Kiri Blakeley covers all things pop culture.
Mark Hughes has the latest on movies.
Eric Savitz is your go-to guy for tech news.
I'll be back at work September 6th.


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Medical community unites against urgent global health threats27 February, 2020
Coda 2020 will enthuse healthcare professionals in Australia to take action across four domains: earth, ethics, cure and education.
ConvaTec welcomes new GM10 December, 2019
ConvaTec has appointed Karen O'Connor as the new General Manager for Australia and New Zealand.
The feminine CEO12 June, 2019 by Laini Bennett
Is it possible to be a feminine CEO and still kick goals? Aged care service provider Benetas CEO Sandra Hills certainly believes so.
A Day in the Life of a CEO06 June, 2019
Barton Private Hospital CEO Jessy McGowan loves her job. Originally a nurse, she keeps the hospital running smoothly and morale high. She shares her day.
Political savvy in times of crisis20 May, 2019
If a crisis struck your organisation, what would you do? Competent leaders can be undone in a crisis, affecting both their business and personal reputation.
Imposter syndrome and tips for managing it20 May, 2019 by Dr Jocelyn Lowinger*
A growing problem in health care is that many highly competent health professionals, even in senior roles, struggle unnecessarily with feeling incompetent.
Not your standard CEO01 May, 2019 by Laini Bennett
Running the Purple House dialysis centres in remote Central Australia is not easy, but Sarah Brown is not your standard CEO. She shares her leadership journey.
Life is too short to not love what you do16 April, 2019 by Laini Bennett
It was the people who believed in HISA CEO Dr Louise Schaper who gave her the confidence to believe in herself.
Taking the leap29 November, 2018 by Laini Bennett
Dr Lesley Braun's willingness to 'get out and try' has led to unexpected career opportunities. She shares her story and lessons learned.
Paying it forward08 November, 2018 by Laini Bennett
Johnson & Johnson Medical Devices ANZ's Managing Director, Susan Martin, on why female managers need to stop placing constraints on themselves.
Dare to be yourself06 September, 2018 by Laini Bennett
As a young mother and sole breadwinner, ACN CEO Kylie Ward was motivated by both need and ambition to pursue a career in nursing management.
The power of one05 June, 2018 by Laini Bennett
With 80% of HESTA's 850K members women, gender diversity and equality are at the top of CEO Debby Blakey's agenda.
The road less travelled09 April, 2018 by Laini Bennett
Recently recognised with an Order of Australia for her leadership roles in psychiatry and medical administration, and now CEO of the National Mental Health Commission, Dr Peggy Brown shares the lessons she's learned during her 30-year career.
A woman of stature05 March, 2018 by Laini Bennett
GS1 Australia CEO Maria Palazzolo talks about her career, her advice for women seeking leadership roles and her proudest moments.
Women need to stop sabotaging themselves!12 December, 2017 by Avril Henry*
Women who want to climb the leadership ladder should follow these golden rules...