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Broccoli casserole is typically a creamy, cheesy, warm dish that you can serve as a side or as a main component to a meal, and luckily it isn't too hard to make! Learn how to make a classic recipe, and then explore different variations to make the recipe your own—whether that's a low-carb dish or one that is chock full of chicken and rice.
Classic Broccoli and Cheese Casserole
- 2 10 ounces (280 g) packages of frozen, chopped broccoli
- 1 cup (240 mL) of mayonnaise
- 1 cup (125 grams) of shredded sharp cheddar cheese
- 1 can of condensed cream of mushroom soup
- 2 eggs
- 2 cups (85 grams) of crushed crackers
- 1 tablespoon (15 mL) of melted butter
Makes 8-10 servings
Did you make this recipe?
Method 1 of 2:
Making a Classic Broccoli and Cheese Casserole
1Steam the frozen broccoli to prepare it for the casserole. Depending on what kind of broccoli you picked up from the grocery store, you may be able to simply microwave the broccoli according the instructions. If you can't steam it in the bag, put the broccoli in a microwave-safe bowl, cover it, and microwave it for 30 seconds to 1 minute, or until it is fork-tender. Cook fresh broccoli by steaming it until tender if you prefer.[1] X Research source
- Be careful when removing the broccoli from the microwave—it'll be really hot, so use oven mitts to protect yourself.
2Drain off the excess liquid from the broccoli. Wear oven mitts to protect your hands if the dish is still hot. Use a colander to get rid of the liquid from the steaming process, or carefully tilt the bowl in the sink while using a large spoon to keep the broccoli from falling out.[2] X Research source
- To let the broccoli lose even more liquid, let it sit for 5-10 minutes after you steam it.
3Preheat the oven and grease a baking dish with cooking spray. Turn your oven on to 350 °F (177 °C), and use a 13 by 9 inches (33 by 23 cm) dish. Spray the bottom and sides of the dish evenly with cooking spray to prevent the casserole from sticking to it.[3] X Research source
- If you don't have a 13 by 9 inches (33 by 23 cm) dish, you'll need to adjust the cooking time appropriately. A deeper dish will need more time to heat through completely.
- If you don't have cooking spray, you could also rub butter over the bottom and sides to the same effect.
4Whisk the eggs together in a small, clean bowl. Carefully crack 2 eggs into a small dish, taking care to keep any egg shell out. Then whisk the eggs for 30 seconds or so until the yolks and the whites are fully combined.[4] X Research source
- The egg serves as a binding agent, though if you don't have any or don't eat eggs, you can eliminate them from the recipe. You may also want to leave out the mayonnaise if you dont eat eggs and you end result may not be ideal.
5Combine the broccoli, mayo, cheese, soup, and eggs in a mixing bowl. Take the drained broccoli, whisked eggs, can of soup, 1 cup (125 grams) of shredded sharp cheddar cheese, and 1 cup (240 mL) of mayonnaise and mix them all together with a suitable spoon until they're incorporated together. Avoid over-mixing, as this could cause the broccoli to break up into smaller pieces.[5] X Research source
- If you don't want to use mayonnaise, you can switch it out for 2 to 3 ounces (57 to 85 g) of cream cheese.
- If you didn't buy already-shredded cheese, you'll need to use a cheese grater to shred the 1 cup (125 grams).
6Pour the mix into the sprayed baking dish. Carefully pick up the large mixing bowl and transfer the ingredients into your baking dish. If you need to, use a spatula to scrape the bottom of the bowl and spread the casserole ingredients out evenly.[6] X Research source
- If you find it hard to maneuver the bowl, have someone else hold it up while you scoop the ingredients out into the pan.
7Crush your crackers and sprinkle them on top of the casserole. Put several handfuls of crackers into a large resealable bag. Use a can, a rolling pin, or your hands to crush up the crackers. Measure out 2 cups (85 grams), and sprinkle them over the casserole.[7] X Research source
- You can use any kind of cracker you like (though avoid sweet crackers). Try a cheese cracker for an extra-cheesy flavor, or use saltines for a salty, crunchy topping.
8Drizzle the melted butter overtop of the dish. Use 1 tablespoon (15 mL) of melted butter. Simply pour it in a zigzag pattern all over the casserole dish. You could also use a butter substitute, like margarine, if you prefer.[8] X Research source
- You can melt butter in the microwave, or simply put cold butter in a small pan and set it on top of the stove as it preheats. The heat should sufficiently warm up the butter.
9Bake the dish for 35 minutes or until it's warm all the way through. After 35 minutes, check the casserole to see if it's browned on top. If you like your casseroles a little more crispy, leave it in the oven for an extra 5 minutes.[9] X Research source
- Each oven is different, so you may need to modify the cook time by 5 or 10 minutes.
10Save leftovers in the fridge for up to one week. Put leftovers in an air-tight container and keep them in the fridge. Reheat leftovers by baking them at 350 °F (177 °C) for about 20 minutes or until they're warmed through, or microwave them for 2 to 3 minutes.[10] X Research source
- Label the leftovers container with some masking tape and the "date prepared" so you know how long they'll be good for.
- Remember to cover your dish if you microwave it, and be careful when you take it out since it'll be really hot to the touch.
Method 2 of 2:
Exploring Variations on the Classic Casserole
1Add rice to your casserole to bulk it up and spread out your ingredients. You can use almost any kind of rice in a broccoli casserole—you just need to make sure to check the recipe to ensure it'll be fully cooked through, depending on the kind you're using. Generally, you'll add about 1 cup (175 grams) of uncooked rice to a casserole recipe.[11] X Research source
- Minute-rice works really well in recipes that simply get mixed together and then baked for 30-40 minutes. Long grain wild rice will be better in a recipe that requires some cooking time on the stovetop so it has time to soften in a liquid of some type.
2Incorporate chicken for added protein and extra flavor. Use 1 to 2 cups (125 to 250 grams) of cooked shredded chicken. Mix it in with the rest of your ingredients before you put the casserole in the oven.[12] X Research source
- This is a great way to use up chicken leftovers. Simply use a fork to shred prepared cooked breasts and thighs.
- For an easy preparation, pick up a rotisserie chicken from the grocery store and use that in your recipe.
3Make your broccoli casserole low-carb and keto-friendly. Nix the crackers and rice, and instead make a simple concoction of broccoli, cheese, sour cream, and chicken. Line a baking tray with steamed broccoli and cover it with a mixture of 1⁄2 cup (120 mL) of sour cream, 1 cup (125 grams) of shredded chicken, and 1 cup (125 grams) of shredded cheese. Bake it in the oven for 15 to 20 minutes at 350 °F (177 °C).[13] X Research source
- This is a great high-protein dish that still tastes indulgent.
4Use fresh veggies to increase the flavor component. While broccoli is, of course, the main component of broccoli casserole, you can also add fresh mushrooms, onion, celery and carrots to make a more flavorful dish (and one that has more vitamins!). Steam or sauté a 1/2 cup (25 grams) of your veggie(s) of choice and cook your recipe as usual.[14] X Research source
- You could also add the veggies in uncooked—they might just not get as soft as they would if you cooked them first.
5Experiment with other kinds of cheese for a new casserole experience. Swap out the classic cheddar cheese for something new—mozzarella, swiss, white cheddar, blue cheese, provolone. Use your favorite kind to see how the recipe changes, or check out some different recipes online to find inspiration.[15] X Research source
- You could even try mixing cheddar cheese with something else, like swiss, to change the flavor profile of the casserole.
- Always use shredded or crumbled cheese for your casserole recipe, as it'll melt a lot better than cheese that hasn't been shredded.
Community Q&A
QuestionHow do I make broccoli and rice casserolewikiHow Staff EditorStaff AnswerGreat question! Rice and broccoli casseroles are delicious! You'll want to add about 1 cup of rice to your recipe, though check the instructions because depending on how the recipe is going to be prepared, you may need to cook the rice beforehand. White rice and long grain wild rice are the most common ones used for broccoli casseroles.
QuestionWhat if my broccoli is deep-frozen?Jacquelyn HelmuthCommunity AnswerYou can put it in your microwave on defrost so it takes less time to thaw, or run cool water on it to thaw.
QuestionDo I cover the baking dish?Worlds next polymathCommunity AnswerYou don't need to, but if your baking dish comes with a lid, then by all means, cover it.
- If you're using fresh broccoli, steam it before adding it to your casserole. This will give it a softer texture and a more vibrant color.Thanks!
Things You'll Need
Making a Classic Recipe
- Microwave
- Colander
- 13 by 9-inch 13 by 9 inches (33 by 23 cm) baking dish
- Cooking spray
- Whisk
- Small mixing bowl
- Large mixing bowl
- Spatula
- Resealable plastic bag
- Cheese grater (optional)
- Can opener
- Long spoon
- Air tight container for leftovers
- ↑ https://www.foodnetwork.com/recipes/paula-deen/broccoli-casserole-recipe-1944351
- ↑ https://www.foodnetwork.com/recipes/paula-deen/broccoli-casserole-recipe-1944351
- ↑ https://www.foodnetwork.com/recipes/paula-deen/broccoli-casserole-recipe-1944351
- ↑ https://www.foodnetwork.com/recipes/paula-deen/broccoli-casserole-recipe-1944351
- ↑ https://www.foodnetwork.com/recipes/paula-deen/broccoli-casserole-recipe-1944351
- ↑ https://www.foodnetwork.com/recipes/paula-deen/broccoli-casserole-recipe-1944351
- ↑ https://www.foodnetwork.com/recipes/paula-deen/broccoli-casserole-recipe-1944351
- ↑ https://www.foodnetwork.com/recipes/paula-deen/broccoli-casserole-recipe-1944351
- ↑ https://www.foodnetwork.com/recipes/paula-deen/broccoli-casserole-recipe-1944351
- ↑ https://www.stilltasty.com/fooditems/index/16635
- ↑ https://www.southernliving.com/recipes/broccoli-rice-and-cheese-casserole
- ↑ https://www.eatwell101.com/broccoli-chicken-casserole-recipe
- ↑ https://yummyinspirations.net/2018/02/keto-broccoli-casserole/
- ↑ https://www.southernliving.com/recipes/broccoli-rice-and-cheese-casserole
- ↑ https://www.eatwell101.com/broccoli-chicken-casserole-recipe
About This Article
To make a broccoli casserole, start by whisking eggs in a bowl. Then, add mayonnaise, shredded cheddar cheese, a can of soup, and some steamed broccoli to the bowl and mix everything together. When you're finished, pour the mixture into a greased baking dish and add some crushed-up crackers and melted butter to the top. Finally, bake the casserole for 35 minutes at 350 degrees Fahrenheit before serving. To learn how to make other kinds of broccoli casserole, like chicken or rice casserole, scroll down!

subset: commoncrawl


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J Sound Services Scores Hole in One at Topgolf®
Global sports entertainment leader Topgolf® recently opened the doors to its new location in Nashville, and in charge of the start-of-the-art sound, video and lighting system in its first 600-seat concert hall, J Sound Services (Nashville) was assigned the task of design and installation. The system includes a NEXO GEO S12 line array, Yamaha CL5 and two Rio3224-D input/output stage boxes. The NEXO speaker system was designed using NEXO NS-1 System Configuration and Modeling Software.
The three-level, 65,000-square-foot venue is the first Topgolf location to include a dedicated music venue. The two-story, 7,900-square-foot concert hall is attached to the Topgolf structure and features an open floor space and second-level VIP deck offering balcony views and premium seating. Both local artists and national acts are already playing at the venue with shows featuring Corey Smith, Los Lobos, George Clinton, to name a few.
The sound system configuration includes ten GEO S1210s and two 1230s (6 per side), six LS18s (three box array flown and three mounted under the stage), four NEXO ID24 speakers for front fills, six monitor mixes of 45-N12s, PS15 speakers over an LS600 for drum fill, four mixes of Shure PSM300s wireless ear monitors, two Focusrite AM2 hardwired ear mixes, and Yamaha SWP1 L2 switches for the Dante network (two 16 port and one 8 port). The system is powered and processed by five NXAmp 4X4 amplifiers with NXDT104 Dante cards. Amplifier tuning and alignment was accomplished using the NEXO NeMo system management software.
"The customer's priority was that the system had to be the best-sounding room in town and suited for live recording and broadcasts," states Jason Spence, President, J Sound Services. "By all accounts, we nailed it! And, we'll soon be testing the broadcast experience with CMT recording their upcoming Crossroads Series in the venue. In choosing the PA, besides sound quality, there was a budget that we needed to adhere to. There are only a couple of PAs on the planet that hit the criteria in my opinion, and NEXO was one of them. Prior to the decision, the Topgolf team did get to hear concerts and events using NEXO systems so that helped with our recommended decision."
Yamaha MRX7-D processors handle audio distribution and integration with the rest of the facility and the matrix processor for Studio Technologies Dante intercom devices. Four Shure ULXD combo systems with four handheld SM58s and four bodypacks, all with rechargeable batteries were also installed. The concert venue's green room is fitted with a pair of Yamaha VXC5F speakers and DCP1-V4S for level and source control from a Yamaha PA2030 mixer/amplifier.
J Sound Services scope of work also included acoustic design, entertainment lighting, video production, and an integrated control system. "A significant factor to the experience in the room is the acoustic design, Spence says, using Design Technik's site-built tuned acoustic system with acoustic design by Kevin Lee Hughes. Everyone that walks into the room always says, 'It feels amazing in here!' I find that an interesting response to the 'sound' of the room."
Lighting and video design was created by Chris Lisle and incorporated fixtures by Martin, Elation, and a GrandMA console. Chroma-Q Inspire and Inspire mini house light fixtures and control were integrated using a Crestron control system. Martin fixtures include 13 Mac Quantum washes, 13 Quantum profiles, 12 Rush Series MH1 profiles, and 20 Rush PAR1s used as truss warmers with 6 Elation Q265 crowd blinders all mounted on a custom-designed TomKat truss. 2 Altman 1000Q medium-throw spotlights, two Chauvet AM Haze 2s, Martin Ether2DMX8, and Doug Fleenor distro are utilized for DMX distribution.
A PixelFlex FLEXTour 2.8 mm video wall built on a trolley system allows the wall to move up and down stage. The wall is approximately 16' wide and 10' tall and supported by a custom TomKat triangle truss.
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Filed under: Uncategorized | Tags: bank of america, big banks, bill clinton, cartels, caught, clinton, clintons, cocaine, cocaine smuggling, compliance department, crime, crime family, criminal, despotism, Dictatorship, drug, Empire, funding, gangsters, government crimes, Hillary Clinton, justice system, mafia, Mena, mexican, money laundering, prison industrial complex, smugglers, U.S. banks, wachovia, wall street, war on drugs, wells fargo
Bank of America Caught Funding Mexican Drug Smugglers AND GET AWAY WITH IT!
Filed under: Uncategorized | Tags: aerosol, anthrax, Bio Weapons, biological warfare, cancer, chemical warfare, chemtrail, chemtrails, connecticut, dengue fever, Dictatorship, doctors, Empire, epidemic, Eugenics, fascism, federal crimes, flu virus, fort detrick, Genocide, government crimes, guatemala, health and environment, Human Experiments, human ginuea pigs, influenza pandemic, malaria, man made disease, man made diseases, maryland, military, military experiment, military experiments, military industrial complex, Mosquito virus, nazi, outbreak, pandemic, Pandemic Influenza, Pentagon, plague, prison industrial complex, secretary of defense, state sponsored terrorism, super weapons, syphilis, toxicity, tuskegee, victimization, war crimes, War On Terror, whitecoats
Biological Weapons Sprayed on U.S. Soldiers
U.S. infected its own citizens with virus
Infect and observe: An army doctor watches as malaria-carrying mosquitoes bite the stomach of inmate Richard Knickerbockers, serving 10 to 14 years, in Stateville in 1945
Daily Mail
February 28, 2011
Pictures have emerged providing the shocking proof that U.S. government doctors once experimented on disabled American citizens and prison inmates.
Such experiments included giving hepatitis to mental patients in Connecticut, squirting a pandemic flu virus up the noses of prisoners in Maryland, and injecting cancer cells into chronically ill people at a New York hospital.
Much of this horrific history is 40 to 80 years old, but it is the backdrop for a meeting in Washington this week by a presidential bioethics commission.
The meeting was triggered by the government's apology last year for federal doctors infecting prisoners and mental patients in Guatemala with syphilis 65 years ago.
U.S. officials also acknowledged there had been dozens of similar experiments in America – studies that often involved making healthy people sick.
A review by the Associated Press of medical journal reports and decades-old press clippings found more than 40 such studies.
At best, these were a search for lifesaving treatments – at worst, some amounted to curiosity-satisfying experiments that hurt people but provided no useful results.
It echoes the deadly and meritless experiments conducted on Jewish concentration camp detainees at the hands of Nazi doctors.
And it will undoubtedly be compared to the Tuskegee syphilis study, where U.S. health officials tracked 600 black men in Alabama who already had syphilis – but didn't give them adequate treatment even after penicillin became available.
Arthur Caplan, director of the University of Pennsylvania's Center for Bioethics, said: 'When you give somebody a disease – even by the standards of their time – you really cross the key ethical norm of the profession.'
Most of the recently revealed studies, from the 1940s to the 1960s, apparently were never covered by news media. Others were reported at the time but the focus was on the promise of enduring new cures, while glossing over how test subjects were treated.
Many prominent researchers felt it was legitimate to experiment on people who did not have full rights in society – people like prisoners, mental patients or the poor blacks.
Laura Stark, a Wesleyan University assistant professor of science in society – who is writing a book about past federal medical experiments – said: 'There was definitely a sense – that we don't have today – that sacrifice for the nation was important.'
Though people in the studies were usually described as volunteers, historians and ethicists have questioned how well these people understood what was to be done to them and why, or whether they were coerced.
Prisoners have long been victimised for the sake of science. In 1915, the U.S. government's Dr Joseph Goldberger – today remembered as a public health hero – recruited Mississippi inmates to go on special rations to prove his theory that the painful illness pellagra was caused by a dietary deficiency (The men were offered pardons for their participation).
CIA Released Dengue-Infected Mosquitoes on U.S. Population
CIA Sprayed LSD on French Village
Filed under: Uncategorized | Tags: 1984, agriculture, big brother, camera ban, corruption, Dictatorship, Empire, farm, farming, fascism, felony, florida, Jim Norman, justice system, nanny state, orwell, PETA, photograph, photographing, Police State, prison industrial complex, SB 1246, Senate, stupid laws, us constitution, Washington D.C.
Photographing cows or other farm scenery could land you in jail under Senate bill
Florida Tribune
February 23, 2011
Taking photographs from the roadside of a sunrise over hay bales near the Suwannee River, horses grazing near Ocala or sunset over citrus groves along the Indian River could land you in jail under a Senate bill filed Monday.
SB 1246 by Sen. Jim Norman, R-Tampa, would make it a first-degree felony to photograph a farm without first obtaining written permission from the owner. A farm is defined as any land "cultivated for the purpose of agricultural production, the raising and breeding of domestic animals or the storage of a commodity."
Media law experts say the ban would violate freedoms protected in the U. S. Constitution. But Wilton Simpson, a farmer who lives in Norman's district, said the bill is needed to protect the property rights of farmers and the "intellectual property" involving farm operations.
Simpson, president of Simpson Farms near Dade City, said the law would prevent people from posing as farmworkers so that they can secretly film agricultural operations.
He said he could not name an instance in which that happened. But animal rights groups such as People for the Ethical Treatment of Animals and Animal Freedom display undercover videos on their web sites to make their case that livestock farming and meat consumption are cruel.
Jeff Kerr, general counsel for PETA, said the state should be ashamed that such a bill would be introduced.
"Mr. Norman should be filing bills to throw the doors of animal producers wide open to show the public where their food comes from rather than criminalizing those who would show animal cruelty," he said.
Simpson agreed the bill would make it illegal to photograph a farm from a roadside without written permission. Norman could not be reached for comment.
Judy Dalglish, executive director for the Reporters Committee for Freedom of the Press, said shooting property from a roadside or from the air is legal. The bill "is just flat-out unconstitutional not to mention stupid," she said.
And she said there are laws already to prosecute trespassing onto property without permission. And if someone poses as a farm employee to shoot undercover video, they can be fired and possibly sued.
"Why pass a law you know will not stand constitutional muster?" Dalglish said.
Simpson said he doesn't think that "innocent" roadside photography would be prosecuted even if the bill is passed as introduced.
"Farmers are a common-sense people," he said. "A tourist who stops and takes a picture of cows — I would not imagine any farmer in the state of Florida that cares about that at all."
Filed under: Uncategorized | Tags: australia, Cannabis, criminalization, criminalize, datura, Dictatorship, DMT, drug war, drugs, Empire, government bureaucracy, health and environment, justice system, mescaline, nanny state, permaculture, Police State, prison industrial complex, psilocybin, salvia, war on drugs
Australia to ban 1000s of plants including national flower
Garden Freedom
February 22, 2011
Legislation being proposed in Australia would criminalize most permaculturists, farmers, gardeners, nurseries and bush regenerators by banning any plant that contains DMT – a naturally-occurring hallucinogen. Five plants are currently criminalized, but the new list will include hundreds (possibly thousands) of other species that are common garden plants and include a significant number of common native plants including the national flower, the wattle. [Image: Australia's National Flower, Acacia pycnantha]
Having any of these plants could get you charged with and convicted of a federal drugs violation. The list can be found here, comprising about four pages of the 41-page document.
The purpose of this new legislation is supposedly to stop major drug trafficking, yet many of the targeted plants have never been traded for drugs and have no value as drug plants, because they only contain traces of the compounds.
The proposed laws will make hundreds or possibly thousands of plants illegal. Many of these are common garden plants that honest, law abiding citizens have legally grown for as long as they remember. The laws will affect the commercial propagators, nurseries, farmers, collectors, botanic gardens, seed merchants, landcare groups and most gardeners.
- Farmers may need to change their pasture grasses and legumes.
- Gardeners, collectors, and botanic gardens will have to remove precious plants from their collections.
- Landcare and dunecare groups may no longer work with the species they are used to and that are native to their region.
- Nurseries may no longer propagate many of the plants they normally propagate.
- Botanists may no longer collect samples from many plants.
- Seedbanks will need to destroy many of their precious seeds.
DMT (dimethyltryptamine) is ubiquitous in nature and is likely to be present in thousands of species. If DMT is found in one species within a genus then it is likely to be found in other species of that genus. Some common plants include grasses, wattles, peas, nutmeg, screwpines, buckwheat, citrus trees, and violets. Also included are legumes, the Leopard tree, Honey Locust, wisteria and cattle forage plants like Desmodium, wetland plants such as the Common Rush (Phragmites), and common pasture grasses (Phalaris spp) — even the ice plants in your Granny's rock garden would be effected by the legislation.
The existing schedule of criminalized plants include:
1. Any plant of the genus Cannabis
2. Enhanced cultivation of any plant of the genus Cannabis
3. Any plant of the genus Erythroxylum from which cocaine can be extracted […] incl E.coca & E.nova-granatense
4. Papaver bracteatum
5. Papaver somniferum
6. All fungi that contain PSILOCIN
7. All fungi that contain PSILOCYBIN
The proposed new schedule will include:
8. Any plant containing MESCALINE including any plant of the genus Lophophora
9. Any plant containing DMT including any plant of the species Piptadenia Peregrine
10. Salvia divinorum (Diviners Sage)
11. Mitragyna speciosa (Kratom)
12. Catha edulis (Khat)
13. Any species of the genus Ephedra which contains ephedrine
14. Any species of the genus Brugmansia
15. Any species of the genus Datura.
Filed under: Uncategorized | Tags: Cannabis, cannabis laws, corruption, drug raid, florida, human rights, justice system, marijuana laws, medical marijuana, oregon, police brutality, police crimes, Police State, prison industrial complex, utah, war on drugs, Weber-Morgan County Narcotics Strike Force
Video Outrage: Utah Police Kill Marijuana Smoker in Own Home
January 18, 2011
Huffington Post reports it as "Police Kill Man In Drug Raid Gone Wrong". So what's the "gone wrong" part?
The police had a no-knock warrant (though they forgot to bring it) to search for drugs. Busting down a citizen's door quickly, loudly, and with overwhelming force is the standard. Sure, the guy they were looking for was a roommate who had already moved out (and they knew it), but it is so vitally important that we find and imprison people smoking weed at home that even a hastily-planned no-knock midnight raid without warrant paperwork is preferable to allowing one more joint to be smoked by a middle aged man in his own home. (Warning: Video is graphic in nature. Story continues after video.)
It is standard operating procedure to send the "Weber-Morgan County Narcotics Strike Force" in all-black full body armor, toting automatic weapons under the cover of night. If police are confronted by someone wielding arms, like, say, an average cannabis consumer with a former drug dealing roommate who grabs a golf club to defend himself when he's suddenly awakened in the dead of night by armored ninjas toting machine guns, they are legally allowed to discharge their firearm to defend themselves and neutralize the suspect.
When you break down a man's door in the middle of the night with guns drawn, somebody dying isn't an unexpected outcome. This is a drug raid gone right. We send stormtroopers into American homes 100-150 times per day on the premise that finding their drugs justifies risking their lives.
Most of the time nobody dies (except the dog) and the few that are killed that you read about are the ones that shock everybody because they didn't have large amounts of drugs or a firearm on them at the time. Yeah, mistakes were made, but you've got to expect some collateral damage in a War on Drugs, right?
Note how many times you read about a raid where "multiple firearms" are found and that is used to justify the excessive force of the raid. How many times do they tell you those multiple firearms are a collection of hunting weapons or sporting arms or handguns for self defense? How about when a "felony amount" of drugs are found, so they must be drug dealers! Have you ever looked at what constitutes a felony level of drugs in some states? It's 3/4 of an ounce in Florida. It's an ounce in Oregon (yes, hippie dippie, medical marijuana-lovin', first-to-decrim Oregon!)
Cannabis is not cocaine. It's not like we need to burst in quickly before the suspect flushes the evidence. If he's got any amount large enough for you to think he's a big time dealer invested in it enough to kill a cop, it's more than can be flushed, burned, or hidden. And if we've been dipping into the stash, unlike cocaine we're not going to go into some lunatic Tony Montana rage and spray cops with an Uzi. Damn, knock on the door and tell us you're Domino's and we're likely to just let you in!
I know legalization might take awhile. Can we at least stop executing people in their homes over pot?
Filed under: Uncategorized | Tags: california, cannabis laws, corruption, dea, justice system, marijuana laws, medical marijuana, Police State, prison industrial complex, san francisco, SF, SFPD, war on drugs
DEA agents mistakenly raid law prof's house
SF Weekly
February 16, 2011
When narcotics officers appeared at a Castro home shortly after 7 a.m. on Jan. 11, they had permission from a judge to search for "proceeds" from an illegal marijuana grow.
The SFPD and DEA found no piles of marijuana money at 243 Diamond St., one of six addresses raided simultaneously in San Francisco that morning. Instead, they found Clark Freshman, who rents the penthouse at the two-unit building. Freshman, a UC Hastings law professor and the main consultant to the television show Lie to Me, was put into handcuffs while in his bathrobe as agents searched, despite Freshman's insistence that they had the wrong place and were breaking the law. "I told them to call the judge and get their warrant updated," he says. "They just laughed at me — I guess that's why they're called pigs."
Soon they may be called defendants in a lawsuit. A furious Freshman has pledged to sue the DEA and the SFPD for unlawful search and seizure of his home.
In his search warrant, Officer Scott Biggs of the SFPD's narcotics unit says that prior to the raid, he spent two days and two nights casing the address looking for Mahmoud Larizadeh, the property's owner. Larizadeh also owns a 13th Street warehouse, a part of which he rents to Bruce Rossignol, a licensed medical cannabis patient who now faces three felony charges for growing pot there.
Biggs describes 243 Diamond as a "two-story, one-unit" building in the warrant. There's no mention of Freshman or Larizadeh's son-in-law or seven-months pregnant daughter who were detained in the downstairs unit that morning. But property records — and a quick visual scan of the property — reveal it to be a three-story, two-unit building. That mistake alone may be enough to invalidate the search warrant.
SFPD offered no comment other than reiterating they had a warrant from Judge Richard Kramer to search 243 Diamond. But Peter Keane, dean emeritus of Golden Gate University's School of Law, says there appears to be a problem. "There's been cases like this in the past where police have a warrant to search [a single residence], then they get there and it's a multi-unit building and they search the whole building. In those cases, people have sued and collected substantial settlements. I think whomever is representing the government better get out his checkbook."
"I've been on the fence for years about the legalization of drugs … and now I'm a victim of this crazy war on drugs," says Freshman, who pledged to sue until "I see [the agents'] houses sold at auction and their kids' college tuitions taken away from them. There will not be a better litigated case this century."
Filed under: Uncategorized | Tags: corruption, justice system, prison industrial complex
Judge caught in 'cash for kids' scandal
February 21, 2011
A former judge has been convicted of taking a $1million kickback from the builder of a juvenile jail in the notorious 'cash for kids' scandal.
Mark Ciavarella sent hundreds of children and teenagers to the private prison for minor crimes after being given the money by the company which ran it.
Some of the children jailed were as young as 10 and at least one killed themselves because the excessive sentences ruined their lives.
Ciavarella, 61, left the bench in disgrace two years ago after the allegations came to light and is now expected to be jailed for at least 13 years.
But instead of being caged immediately he was allowed to walk out of court – right into a barrage of abuse from the mother of an all-star wrestler who committed suicide after he sent him to jail.
Edward Kenzakoski, 17 was never the same after being jailed for a first-time minor drug offence, his mother Sandy Fonzo raged.


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Stay tuned for our 2108 workshop dates!
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There will be plenty of opportunity to practice some propagation methods and take home the results!


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Netmarble Corp. announced today that pre-registration for Magic: ManaStrike is now open. Magic: ManaStrike is the first game developed by Netmarble Monster for the Wizards of the Coast franchise Magic: The Gathering. Magic: ManaStrike will be globally available on the App Store and Google Play.
Anyone who pre-registers to download Magic: ManaStrike will receive a suite of in-game prizes once the game launches and they complete the tutorial. These include Gold (in-game currency), Gems (premium currency), one Player Icon, and five emoji themed after Magic: The Gathering's iconic Planeswalkers.
Magic: ManaStrike is a mobile combat game that brings spells inspired by Magic: The Gathering's cards and characters to life in a new genre. After losing a war with the Planeswalkers, Magic: The Gathering's most powerful villain Nicol Bolas creates a parallel universe to find the Planeswalkers' weaknesses. Players enter a contract with Nicol Bolas to provide combat data by controlling Planeswalkers and units in his universe.
The game offers simple, tactical, and strategic gameplay as players collect new cards and enhance their units to suit their individual playstyles and strategies. Gameplay spotlights many customized strategies between opponents in intense Player vs. Player (PvP) matches. As players progress, they can experience Magic: The Gathering's vast universe of original spells and characters presented with impressive Planeswalker animations in high-quality 3D.
Representatives from Netmarble and Wizards of the Coast sat down to showcase highlights of the Magic: ManaStrike development process, including key features, art, and how Magic: ManaStrike was conceived.
For more information, please visit Magic: ManaStrike's official website. Also, please follow Magic: ManaStrike on Facebook and Twitter.


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Committed to Results, Excellence & You.
Lifestyle and Wellness Care You Can Rely On.
– Chiropractor at Caulfield Family Chiropractic ®
Dr Stacy Budlender chiropractor at Caulfield Family Chiropractic ® grew up wanting to help people, she graduated from as a Chiropractor from RMIT in 2006. From there, she created Caulfield Family Chiropractic ® in 2009, which has remained and grown in its Caulfield location. Dr Stacy Budlender (Chiropractor) has renovated several times to ensure that the best atmosphere and technological capabilities are provided for the patients of the practice. Dr Stacy Budlender's passion for quality health services drove her to attend some of the nations best courses during her career.
Dr Stacy Budlender (Chiropractor)enjoys spending time with her 6 children and oversees all the clinical procedures at Caulfield Family Chiropractic ®
Besides being the clinic owner, Dr Stacy Budlender is an experienced chiropractor with over 10 years in the field. Dr Stacy was responsible for implementing our unique action plans that have resulted in our standout results and she guides our practitioners. Dr Stacy will not allow any patient of ours to be less than their best. She also has extensive post-graduate training in paediatric chiropractic and is passionate about children's wellbeing. Dr Stacy's goal in her career is to empower people to make good health choices in their day to day lives.
We help people suffering from back pain and neck pain, without relying drugs and medication.
We do this through Gonstead Chiropractic. It's a special technique designed to get you out of pain and get you loving life again. No more popping tablets to get you through your day. No more frustration with constant back and neck pain. Just follow our recommendations and feel your back and neck pain ease.The best part is, it's simple and this is what the chiropractors at Caulfield Family Chiropractic™ see all the time. How this works is that instead of not knowing what you should be doing, we show you how to ease that back & neck pain and show you how to stop them from coming back. We see the best results with patients who are willing to make time for themselves; open to changing their habits; and take full responsibility for their outcome.
Our Dedicated Team
DR. STACY BUDLENDER – Chiropractor at Caulfield Family Chiropractic ®
Dr Stacy Budlender chiropractor at Caulfield Family Chiropractic ® grew up wanting to help people, she graduated from as a Chiropractor from RMIT in 2006.
MICHAEL BUDLENDER – Caulfield Family Chiropractic ®
Michael Budlender graduated as a Remedial Massage Therapist in 2002 with a Dip, Health Sci. He has since completed courses in business and marketing. Michael started out his career treating athletes competing at olympic levels and with some AFL teams.
DR. JAKE BRIGHT – Chiropractor at Cauflield Family Chiropractic ®
Dr. Jake graduated as a Chiropractor with distinction, no small feat. Dr. Jake (Family Chiropractor) is the mastermind behind our famous information sheets and popular health workshops. He has transformed the way in which patients are educated on health and his reputation stands firm on his impressive results.
After completing a Myotherapy course at SSNT Lauren enjoys putting her skills into practice. Lauren has learnt cupping, dry needling and a variety of manual therapy techniques. Lauren has experience in exercise prescription. As a Myotherapist at Caulfield Family Chiropractic Lauren says she is passionate about health and fitness and the benefits they can provide.


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text: Tom-Joad Posted July 11, 2019 A long, long time ago, when I graduated from university, I wrote a thesis about American popular music and American identity. I worked on lyrics by Robert Johnson, Woody Guthrie, Johnny Cash, Bob Dylan and, of course, Bruce. My focus was the uses of imagery of the road, trains and just the idea of travelling . The funny thing about this is, when one thinks about it, places like roads, railways and we can even include airports and shopping malls, are pretty special places. They're places that usually have no identity, they have no history. They're purpose is not to be places where one is but through which one passes. They're lonely and impersonal. They have universal signs that will tell you where to go and from the moment you walk in until the moment you walk out, your journey is pretty much predetermined. The sense of loneliness and and disconnection felt by many who spend most of their lives living in these places instead of going through them is a reflection of this. Anyway, American popular music has been trying to turn this on its head for a long time. There is a clear sense that American identity is attached to this idea of movement, of ever expanding frontiers, of loneliness (often glorified and individual freedom) and Bruce has been a master at doing that. There's no shortage of example where Bruce uses this kind of imagery attached to ideas of identity, communion and belonging. Wester Stars seems to be a new take on this. Of course, the romantic notions are still there (see Hitchhiking) but on songs like Hello Sunshine, there's something different there. Bruce has been hinting at this since he started introducing the acoustic version of Born to Run saying it's not about "running and keep on running" but it was about going out there searching "for a connection". Now, maybe for the first time (?), Bruce speaks of the road as a siren whose call can be very alluring but no less dangerous. "You know I always like that empty road Nowhere to be and miles to go But miles to go is miles away" "Hello Sunshine" is full of "buts" that warm the listener of the dangers of these romantic notions. This might very well be an old man's take on it, someone who just needs a bit of sunshine and a place he can call home. But I think there's a lot more truth here than there is on "these two lanes will take us anywhere". Or maybe that's just me also growing old... TL:DR Bruce is a fucking genius! 12 3 Quote Share this post Link to post Share on other sites


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Do you have a passion for writing? We mean like a deep passion – the kind of passion that excites you to put fingers to keys and pump out content all day long.
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Content is the bread and butter of what we do here at The Squad. It is the foundation for all of the strategy, wow-factor, and results that we produce. And we believe that content should be carefully crafted for each and every one of our client.
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If being a content creator and curator sounds like a dream, apply by filling out the form. Not sure yet? Keep scrolling to learn more about being a Squad Copywriter and Storyteller.
A successful Squad Copywriter and Storyteller:
- Is familiar with using search engines (primarily Google) to locate products, services, and reference material.
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If you've got the chops, fill out the form to apply.


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© Images & Video Copyright Lowes Computers | Photojournalist |Paul R. Lowes | AKVNEWS.COM
Harrison Township, Pa. – Police and Paramedics from Harrison Township responded to an area near #10 Gate in Natrona about 9:00 am Wednesday morning after a male was struck by a coil on a jobsite.
Once located inside the plant, paramedics put a helicopter on stand-by after reports the man was hit in the head with the coil suffering a laceration. The male was transported to the Burtner Road lading zone adjacent to the Citizens Hose Fire and EMS emergency response complex.
StatMedivac arrived on the scene approximately 11 minutes after dispatch. Flight crews made their way to the EMS truck for patient evaluation and packaging. The male was sitting upright on the stretcher with a neck collar attached and he was wheeled to the awaiting helicopter. The extent of his injuries was unknown.
© Images & Video Copyright Lowes Computers | Photojournalist |Paul R. Lowes | AKVNEWS.COM


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Today's Fraud News from around the world:
Bellevue Developer Charged In Investment Fraud Case: A Bellevue developer suspected of bilking more than 250 Chinese investors out of millions of dollars on two real estate projects has pleaded guilty to.: Google Alert – Fraud
Unlicensed chiropractor sentenced for insurance fraud: GAINESVILLE, Texas — A man convicted of insurance fraud was ordered to pay back over $ 1 million in restitution. Investigators say they were tipped …: Google Alert – Fraud
Hants County man pleads guilty to fraud in m Ponzi scheme: A Hants County man who masterminded a Ponzi scheme that bilked investors of millions of dollars has pleaded guilty to a charge of fraud over $ 5,000.: Google Alert – Fraud
Ex-Barboursville doctor admits to committing fraud for pills: BARBOURSVILLE, W.Va. (AP) – A former Cabell County physician has admitted to writing a fraudulent prescription to illegally obtain more than 100 …: Google Alert – Fraud
University falls victim to €360000 fraud: A gardai investigation is being carried out into a €360,000 fraud at NUI Maynooth after the university reported the alleged crime in its end-of-year …: Google Alert – Fraud
New London woman charged with unemployment fraud: Fallyn V. Fonville-Smith, 31, of 70 Farmington Ave., Unit 3F, was arrested by inspectors from the Unemployment Compensation Fraud Unit of the office …: Google Alert – Fraud
'Kong, the Origin' Film at Center of Fraud Suit: The film at issue is a sci-fi adaptation of Chinese literary classic 'Journey to the West,' which tells the story of Sun Wukong, the Monkey King.: Google Alert – Fraud
Greenville police director pleads not guilty to health care fraud: Greenville Public Safety Director Mark Reiss was arraigned at the Montcalm County courthouse for allegedly leaving his ex-wife on his insurance after …: Google Alert – Fraud
'I too was a victim,' accused says in fraud, theft trial: KITCHENER — Former financial guru Daniel P. Reeve denied one accusation after another, on trial for fraud and theft after 41 investors lost $ 10 …: Google Alert – Fraud
Deutsche Bank Agrees to Resolves Tax Fraud Lawsuit: On Wednesday, Deutsche Bank agreed to pay $ 95 million to resolve a lawsuit from the U.S. government accusing the German bank of tax fraud.: Google Alert – Fraud


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OPINION: Nigeria has suspended plans to borrow $22.7 billion to fund its ambitious 2020 budget, endangered by falling oil prices and a collapsing market for oil and gas exports as coronavirus hammers the global economy.
The Opec nation desperately needs to refocus on developing a non-oil economy and prioritising capital outlay for job creation, albeit deferring "non-critical expenditure" until markets stabilise, Finance Minister Zainab Ahmed told a recent convention in Abuja.
Fifty cargoes of Nigerian crude are wandering the ocean looking for off-takers, while a dozen liquefied natural gas tankers are at sea "with no hope of finding buyers" as demand crumbles, said Nigerian National Petroleum Corporation managing director Mele Kyari.
With Persian Gulf oil producers offering discounts and Opec in disarray, Kyari is forced to admit that in this market only those with low operating and production costs will survive — a tough pill to swallow for a country that produced for a competitive $5 per barrel just two decades ago.
Saudi Arabia on average pumps crude for under $5 per barrel, while Kyari calculates Nigeria's cost at $17, and that figure is plainly rising.
The cause? Corruption, ineffective regulation, an infrastructural deficit, oilpatch insecurity and asphyxiating bureaucracy — that is the opinion of Minister for Petroleum Resources Timipre Sylva, who last October reckoned the cost of getting oil out of the Niger Delta at $35 per barrel.
The solution is clear — slash paperwork and speed up approvals, revise laws penalising the deep offshore and allow whatever mergers and acquisitions are proposed to entice foreign capital back.
Last weekend's tragedy in Lagos, where a gas explosion destroyed an entire neighbourhood, taking more than a score of lives, serves to emphasise the pitfalls of poor safety planning, yet the country must now move swiftly.
Getting out of this fix will take grit if Nigeria seeks to restore borrowing capacity, reassure bond markets and keep the currency from freefall. Now may be the time to rally investors, open the taps and pump.
(This is an Upstream opinion article.)


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Historic building catches fire overnight in Hawi
KAILUA-KONA — Fifteen people were evacuated from a Hawi hotel after a fire erupted from an adjoining historic building overnight, officials confirmed this morning.
At approximately 11:23 p.m. Wednesday, Hawaii Fire crews received a call about a structure at Kohala Village Inn & Hub. When they arrived on scene, firefighters found the interior of the structure fully involved with flames through the roof.
The historic building and restaurant with adjoining hotel as well as multiple business establishments were caught up in the blaze. Fifteen guests were evacuated from the hotel, officials say.
"Roof partially collapsed, all exterior walls and most interior walls still intact," fire officials say.
The flames were contained to the involved structure using three turrets and multiple handlines. To get to the seat of the fire, officials say, crews made entry in the center of the building.
Crews are still on scene and cause is currently under investigation. Officials estimate $1 million in damages.
No injuries were reported. Twenty-two firefighters responded to battle the blaze, which was contained at 3:27 a.m.
This is a developing story. More information will be provided as it becomes available.


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|In stock
The Papilio Ulysses is a large swallowtail butterfly of Australia, Indonesia, Papua New Guinea and the Solomon Islands. They typically have a wingspan of about 14 cm. The upperside of the wings are an iridescent electric blue; the underside is a more subdued black and brown.
When the butterfly is perched the intense blue of its wings is hidden by the plainer brown underside of its wings, helping it to blend in with its surroundings. When in flight, the butterfly can be seen hundreds of meters away as sudden bright blue flashes. Males are strongly attracted to the colour blue, including blue objects which are sometimes mistaken for females.
This beautiful Papilio Ulysses is particularly decorative and a real eye-catcher due to its beautiful colour.
The insects are prepared with great care in our atelier in Leuven (Belgium).


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FLAST CASE SUMMARY: Danvers 2018: Procedural Mistakes/Abuse Of Process
Danvers & Danvers [2018] FamCAFC 262 (21 December 2018)
- Final parenting orders made by consent in August 2016.
- The property settlement orders were made in June 2017, that included sale of the house both parties shared, with the division of property interests proceeds for 55%/45% in the husbands favour.
- The husband appealed the property settlement orders and it was dismissed in December 2017.
- The wife in May 2018 seeks orders for the removal of the husband from the property pursuant to the property orders made so she could sell the house. This submission included but is not limited to; the wife's full control of the sale with engaging real-estate agents and listings, the husband to be abstained from entering the property or approaching the real-estate agents, for the net proceeds of the house sale to be held in the wife's lawyers trust account until further order. The court granted this.
- The husband then files an application in a case in June 2018 seeking a stay of the orders awaiting the outcome of his appeal for the May 2018 orders.
- The judged dismissed the appeal for there was no appeal orders filed in relation to the May 2018 orders and the appeal period had expired.
- The husband then files again an amended application in a case in July 2018. The husband sought an extensive list that included but is not limited to; the wife be declared a vexatious litigant, the wife be referred to the AFP for perjury, removal of the children from the airport watch list, separating siblings- to have one child reside with him and alternate the other child's visitations, that he would have sole responsibility of the sale of the house.
- This appeal was dismissed again on July 2018.
- Then finally the husband sought parenting orders that already had been determined and filed an Application in a Case in relation to property orders he was seeking to re-litigate again December 2018.
- Was there apprehended bias against the husband?
- Was there procedural unfairness towards the husband?
- Did the trial Judge make a mistake with the fathers parenting matter that he tried to re-litigate?
- Did the judge make a mistake in relation to ordering costs to the husband to pay the wife when the wife's solicitor failed to file a notice of address for service in relation to the family matters?
The appeal dismissed – no order as to costs.
The judge disproved the apprehended bias claim, 'the issue of bias was not raised with his Honour at any stage during the hearing, and the husband cannot now raise it on appeal' (Vakauta v Kelly). Moreover, It was established the wife's lawyer not serving the Notice of Address of Service was a 'hollow complaint' given the situation. The father conceded in his argument that he couldn't afford legal representation anyway, which cancelled out his argument of needing to know if the wife had legal representation so he may get legal representation too, the husband was always afforded the opportunity to have legal representation regardless. As a result, the husband did not demonstrate why the wife should be reprimanded for her lawyer's actions that appeared for her.
Furthermore, It was established the judge did not afford the husband to make lengthy submissions, however it was evidently proven that the husband attempts to re-litigate the settled property orders was an abuse of process.
Moreover, there was no evidence for the claims the wife needs to be referred to the APF for her allegations of domestic violence and therefore also refused to proclaim her a vexatious litigant; the wife was the respondent not the applicant in the proceedings.
Moving forward, the husband attempted to vary the parenting orders through the amended Application in Case July 2018 in relation to the property issues, instead he should of filed an Initiating Application to commence a new parenting case and attempted mediation first, which is a pre-requisite. The judge dismissed the application due to abuse of process of parenting matters. It was concluded there was no appealable error in the judge not assisting the husband with the understanding of the process of how to initiate parenting orders.
The husband appears to be confused and believes the wife's lawyer are seeking costs themselves and is disputing this, however it is the wife who assumes costs and is seeking the costs from the husband.The wife had to occur an expense defending a pointless application in relation for the stay of orders may 2018, as no appeal was actually made by the husband, it could never of succeeded, there was no basis to complain of procedural unfairness.
There were various points made throughout this case where the husband fails to understand the process of timing the submissions and when to raise issues in court and in what application.


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Ultraviolet (UV) irradiation induces skin pigmentation, which relies on the intercellular crosstalk of melanin between melanocytes to keratinocytes. However, studying the separate effects of UVA and UVB irradiation reveals differences in cellular response. Herein, we show an immediate shedding of extracellular vesicles (EVs) from the plasma membrane when exposing human melanocytes to UVA, but not UVB. The EV-shedding is preceded by UVA-induced plasma membrane damage, which is rapidly repaired by Ca2+-dependent lysosomal exocytosis. Using co-cultures of melanocytes and keratinocytes, we show that EVs are preferably endocytosed by keratinocytes. Importantly, EV-formation is prevented by the inhibition of exocytosis and increased lysosomal pH but is not affected by actin and microtubule inhibitors. Melanosome transfer from melanocytes to keratinocytes is equally stimulated by UVA and UVB and depends on a functional cytoskeleton. In conclusion, we show a novel cell response after UVA irradiation, resulting in transfer of lysosome-derived EVs from melanocytes to keratinocytes.
Funding Agencies|Swedish Research Council; Swedish Cancer Society; Welander-Finsen Foundation; County Council of Ostergotland; Stiftelsen Olle Engkvist Byggmastare; Konung Gustav V och Drottning Victorias Frimurarestiftelse; Ostgotaregionens Cancerfond
The article contains 2467 authors of which five are affiliated with LiU and have the following author order:
Author no. 177: Andrea Boman
Author no. 968: Katarina Kågedal
Author no. 1106: Tino Kurz
Author no. 1449: Simin Mohseni
Author no. 1559: Karin Öllinger
Exocytosis of lysosomal contents from platelets has been speculated to participate in clearance of thrombi and vessel wall remodelling. The mechanisms that regulate lysosomal exocytosis in platelets are, however, still unclear. The aim of this study was to identify the pathways underlying platelet lysosomal secretion and elucidate how this process is controlled by platelet inhibitors. We found that high concentrations of thrombin induced partial lysosomal exocytosis as assessed by analysis of the activity of released N-acetyl--glucosaminidase (NAG) and by identifying the fraction of platelets exposing the lysosomal-associated membrane protein (LAMP)-1 on the cell surface by flow cytometry. Stimulation of thrombin receptors PAR1 or PAR4 with specific peptides was equally effective in inducing LAMP-1 surface expression. Notably, lysosomal exocytosis in response to thrombin was significantly reduced if the secondary activation by ADP was inhibited by the P2Y(12) antagonist cangrelor, while inhibition of thromboxane A(2) formation by treatment with acetylsalicylic acid was of minor importance in this regard. Moreover, the NO-releasing drug S-nitroso-N-acetyl penicillamine (SNAP) or the cyclic AMP-elevating eicosanoid prostaglandin I-2 (PGI(2)) significantly suppressed lysosomal exocytosis. We conclude that platelet inhibitors that mimic functional endothelium such as PGI(2) or NO efficiently counteract lysosomal exocytosis. Furthermore, we suggest that secondary release of ADP and concomitant signaling via PAR1/4- and P2Y(12) receptors is important for efficient platelet lysosomal exocytosis by thrombin.
Funding Agencies|County Council of Ostergotland; Swedish Research Council
Ultraviolet (UV) irradiation is a risk factor for development of malignant melanoma. UVA-induced lysosomal exocytosis and subsequent cell growth enhancement was studied in malignant melanoma cell lines and human skin melanocytes. UVA irradiation caused plasma membrane damage that was rapidly repaired by calcium-dependent lysosomal exocytosis. Lysosomal content was released into the culture medium directly after irradiation and such conditioned media stimulated the growth of non-irradiated cell cultures. By comparing melanocytes and melanoma cells, it was found that only the melanoma cells spontaneously secreted cathepsins into the surrounding medium. Melanoma cells from a primary tumour showed pronounced invasion ability, which was prevented by addition of inhibitors of cathepsins B, D and L. Proliferation was reduced by cathepsin L inhibition in all melanoma cell lines, but did not affect melanocyte growth. In conclusion, UVA-induced release of cathepsins outside cells may be an important factor that promotes melanoma growth and progression.
Funding Agencies|Swedish Research Council; Ostgotaregionens Cancer Foundation; Stiftelsen Olle Engkvist Byggmastare; Swedish Cancer Society; Welander-Finsen Foundation
BACKGROUND: Ultraviolet (UV) radiation constitutes an important risk factor for malignant melanoma, but the wavelength responsible for the initiation of this disease is not fully elucidated. Solar UV induces multiple signalling pathways that are critical for initiation of apoptotic cell death as a cellular defence against malignant transformation.
OBJECTIVES: To evaluate the involvement of the transcription factors nuclear factor (NF)-κB and activator protein (AP)-1 in the signalling pathways induced by UVA or UVB irradiation in human melanocytes.
METHODS: Primary cultures of normal human melanocytes were irradiated with UVA or UVB, and the concomitant DNA damage and redox alterations were monitored. The resulting activation of the NF-κB and AP-1 signalling pathways and subsequent apoptosis were studied.
RESULTS: UVB irradiation causes DNA damage detected as formation of cyclobutane pyrimidine dimers, while UVA induces increased levels of 8-hydroxydeoxyguanosine and lipid peroxidation. UVA and UVB initiate phosphorylation of c-Jun N-terminal protein kinase and extracellular signal-regulated kinase, and the apoptosis signalling pathways converge into a common mechanism. Downregulation of c-Jun suppresses AP-1-mediated signalling and prevents apoptosis upstream of lysosomal and mitochondrial membrane permeabilization, whereas inhibition of NF-κB by SN50 increases apoptosis.
CONCLUSIONS: We conclude that AP-1 induces proapoptotic signalling, whereas NF-κB is a key antiapoptotic/prosurvival factor in both UVA- and UVB-induced cellular damage in human melanocytes, which might in turn impact melanoma development and progression.
Funding text:
This study was supported by the Swedish Research Council, the Swedish Cancer Society, the County Council of Ostergotland, Konung Gustav V och Drottning Victorias Frimurarestiftelse and the Welander-Finsen Foundation.
The aim of the present study was to investigate the role of 12-lipoxygenase (12-LOX) on platelet-induced airway smooth muscle cell (ASMC) proliferation. Co-incubation of platelets and ASMC caused platelet activation as determined by morphological changes. Simultaneously, reactive oxygen species (ROS)-generation was detected and ASMC proliferation (measured by using the MTS assay) increased significantly. Furthermore, we found that the 12-LOX inhibitors cinnamyl-3,4-dihydroxy-α-cyanocinnamate (CDC) and Baicalein prevented platelet activation in a co-cultures of platelets and ASMC. The inhibitory effect of CDC and Baicalein on platelets was also registered in a pure platelet preparation. Specifically, the 12-LOX inhibitors reduced collagen-induced platelet aggregation both in the presence and absence of external added fibrinogen. Importantly, platelet-induced ASMC proliferation and ROS production generated during the platelet/ASMC interaction was significantly inhibited in the presence of 12-LOX inhibitors. In conclusion, our findings reveal that 12-LOX is crucial for the observed enhancement of ASMC proliferation in co-cultures of platelets and ASMC. The present result suggests that 12-LOX activity is important in the initial step of platelet/ASMC interaction and platelet activation. Such action of 12-LOX represents a potential important mechanism that may contribute to platelet-induced airway remodelling.
Photo-cytotoxicity of zinc oxide (ZnO) nanowires (NWs) either bare or conjugated with photosensitizers was studied in dark and after ultraviolet light exposure, in human melanoma and foreskin fibroblast cells. ZnO NWs were grown on the capillary tip and then coated with photosensitizer. This coated tip was used as pointer for intracellular insertion of ZnO NWs and photosensitizer. ZnO NWs pointer was inserted into a specific cell and then irradiated with ultraviolet (UVA), which led to loss of mitochondrial membrane potential, as estimated by loss of the Mitotracker Red staining. Dissolved ZnO NWs showed cytotoxicity as detected by MTT viability assay and morphological evaluation. UVA-irradiation enhanced the toxicity and caused the production of reactive oxygen species (ROS) resulting in cell necrosis. ZnO NWs were photo-toxic for both normal and cancer cells, questioning their bio-safety.
The previous status of this article was Manuscript and the working title was Photo toxicity of Zinc Oxide Nanowires in Human Melanoma and Fibroblast Cells.
Lysosomes are acidic organelles essential for degradation, signalling and cell homoeostasis. In addition, they play a key role in cell death. Permeabilization of the lysosomal membrane and release of hydrolytic enzymes to the cytosol accompanies apoptosis signalling in several systems. The regulatory mechanism of lysosomal stability is, however, poorly understood. Lipophilic or amphiphilic compounds with a basic moiety will become protonated and trapped within lysosomes, and such lysosomotropic behaviour is also found in many pharmacological drugs. The natural sphingolipid sphingosine exhibits lysosomotropic detergent ability and is an endogenous candidate for controlling lysosomal membrane permeabilization. The lysosomotropic properties of certain detergents might be of use in lysosome-targeting anticancer drugs and drug delivery system in the future. The present review summarizes the current knowledge on the targeting and permeabilizing properties of lysosomotropic detergents from a cellular and physicochemical perspective.
Funding Agencies|Swedish Research Council [3214]; Konung Gustaf V:s och Drottning Victorias Frimurarestiftelse
Solar radiation is an important risk factor for skin cancer, the incidence of which is increasing, especially in the fair-skinned populations of the world. While the ultraviolet (UV)B component has direct DNA damaging ability, UVA-induced effects are currently mainly attributed to the production of reactive oxygen species. In our recent study, we compared the effects of UVA and UVB radiation on human keratinocytes and found that UVA-induced plasma membrane damage was rapidly repaired by lysosomal exocytosis, which was detected based on the expression of lysosomal membrane associated protein-1 (LAMP-1) on the plasma membrane of non-permeabilized cells. Later, the keratinocytes died through caspase-8 mediated apoptosis. In contrast, the plasma membranes of keratinocytes exposed to UVB showed no LAMP-1 expression, and, although the cells died by apoptosis, no initial caspase-8 activity was detected. We have also demonstrated the occurrence of UVA-induced lysosomal exocytosis in reconstructed skin and shown the relocation of lysosomes from the center of cells to the vicinity of the plasma membrane. Thus, we suggest that lysosomal exocytosis also occurs in keratinocytes covered by the stratum corneum following exposure to UVA. Our findings provide new insight into the mechanism of UVA-induced skin damage.
Article Addendum to: H Appelqvist, P Waster, I Eriksson, I Rosdahl, K Ollinger. Lysosomal exocytosis and caspase-8-mediated apoptosis in UVA-irradiated keratinocytes. Journal of Cell Science 2013; 126: 5578- 5584. DOI: 10.1242/jcs.130633
Ultraviolet (UV) irradiation is a major environmental carcinogen involved in the development of skin cancer. To elucidate the initial signaling during UV-induced damage in human keratinocytes, we investigated lysosomal exocytosis and apoptosis induction. UVA, but not UVB, induced plasma membrane damage, which was repaired by Ca2+-dependent lysosomal exocytosis. The lysosomal exocytosis resulted in extracellular release of cathepsin D and acid sphingomyelinase (aSMase). Two hours after UVA irradiation, we detected activation of caspase-8, which was reduced by addition of anti-aSMAse. Furthermore, caspase-8 activation and apoptosis was reduced by prevention of endocytosis and by the use of cathepsin inhibitors. We conclude that lysosomal exocytosis is part of the keratinocyte response to UVA and is followed by cathepsin-dependent activation of caspase-8. The findings have implications for the understanding of UV-induced skin damage and emphasize that UVA and UVB initiate apoptosis through different signaling pathways in keratinocytes.
The previous status of this article was manuscript with the title Lysosomal exocytosis repairs the plasma membrane after UVA and is followed by caspase-8 induced apoptosis.


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The 2018 Jaguar E-PACE is the second crossover to come from Jaguar. It's an all-new model this year, and fans of the brand across Hardeeville, Bluffton, and Hilton Head Island are excited to hear all the latest.
In this car review, we want to give you an in-depth look at this luxury subcompact SUV, from its impressive cargo space to its lineup of powerful engines. Read on to learn whether this is the luxury crossover you've been dreaming of-and drop us a line at Jaguar Hilton Head if you want to learn more!
Related Post: 2019 Jaguar E-PACE Review
2018 E-PACE: Exterior Features
From the outside, the 2018 E-PACE looks like a Jaguar, with its sporty honeycomb mesh grille, bookended by sleek LED headlamps. This isn't your boxy 90s-era crossover: The sweeping roofline of the E-PACE melds with a stylish spoiler at the rear, which only adds to this vehicle's athletic and dynamic profile.
The E-PACE offers a wide range of modern wheel designs to customize the look of this sporty SUV. If you're ready to go bold, the 21-inch wheels really pop and add a dose of distinction to the E-PACE. On top of this ride, the available fixed panoramic glass roof lets in the light and makes this small crossover feel plenty spacious.


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This is my brief understanding of Information Visualization.
Information Visualization (IV) is the study of (interactive) visual representations of abstract data to reinforce human cognition. (from Wikipedia) According to the definition, I created the following figure, which differentiated the special application and the study area of IV. For example, the study of human perception is not the special application of IV, but is very critical to this area since it can provide guidance for a better visualization design that can be effectively perceived by human.
One way to answer this question is simply locate the area in a hierarchical classification system. According to the ACM Computing Classification System 2012, IV can be found here: Human-centered computing –> Visualization –> Visualization application domains –> Information visualization
Its original motivation was to transit the tabular presentation of data into graphics. That was the start of the graphics design. J.H. Lambert and William Playfair were considered the inventors. Bertin and Tufte made fundamental contributions to the area. (from WikiViz) PS: People hold different opinions on the start time of VI. It can even be traced back to thousands of years. But I think the key point of this question is to know the motivation, which is to establish a better representation of information to solve people's problems.
(from Wikipedia)
A few examples:
According to the book Data Visualization from Ward et al., there are open issues of
I created a picture to illustrate where these issues stay within the pipeline of IV.


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Floor Tiles Textures
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Foundation Mechanics (F3207)
15 credits, Level 3 (sub-degree)
Autumn teaching
Topics covered in this module include:
- Units and dimensions: mass, length, time and derived units.
- Kinematics in one dimension: displacement, speed, velocity and acceleration.
- Linear motion with uniform acceleration, the equations of motion and gravitational acceleration.
- Vectors and scalars: the components of a vector and the addition and subtraction of vectors.
- Motion in more than one dimension: projectiles.
- Forces and Newton's laws of motion: force and mass, Newton's 3 laws, gravitational force, normal forces, tension, frictional forces and coefficients of friction.
- Work and energy: work done by a constant force, the work-energy theorem, kinetic energy, potential energy, conservative and non-conservative forces and the conservation of mechanical energy.
- Linear momentum: linear momentum, impulse, conservation of linear momentum and elastic and inelastic collisions in one and two dimensions.
- Uniform circular motion: centripetal forces, centripetal acceleration and satellites.
- Rotational kinematics: angular displacement, angular velocity, angular acceleration, the equations of rotational kinematics with constant angular acceleration and rolling motion.
- Statics of rigid bodies: torque, action of forces, torques on rigid bodies, rigid bodies in equilibrium, centre of mass, centre of gravity and stability.
- Rotational dynamics of rigid bodies: Newton's second law for rotation about a fixed axis, the moment of inertia, work and kinetic energy associated with rotational motion, angular momentum of a rigid body and conservation of angular momentum.
50%: Lecture
25%: Practical (Workshop)
25%: Seminar (Class)
20%: Coursework (Problem Set)
80%: Examination (Unseen examination)
Contact hours and workload
This module is approximately 150 hours of work. This breaks down into about 44 hours of contact time and about 106 hours of independent study. The University may make minor variations to the contact hours for operational reasons, including timetabling requirements.
This module is running in the academic year 2020/21. We also plan to offer it in future academic years. It may become unavailable due to staff availability, student demand or updates to our curriculum. We'll make sure to let our applicants know of such changes to modules at the earliest opportunity.
This module is offered on the following courses:


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"Is there a place to go for hip hop training?"
"I'm having trouble building my hip hop program."
"Why can't I find a good hip hop teacher?"
"What do you teach in your hip hop classes?"
Do any of these pertain to you? Hip Hop and street dance can be a funny thing. There are many places around the country that get it right. However, so many places are still having trouble. I believe there are about 3 kinds of instructors out there teaching hip hop classes:
knowledgeable Artists
effective teachers
talented dancers
Whats actually quite rare is when you get all 3 in one package. There are many talented (and sometimes very famous ) dancers that possess zero skills in teaching. There is a disconnect. These teachers are those who "Do" and "Show" instead of instruct. Of course, what is most common are the very many wonderful teachers out there that must lean on training in other areas and their observation of hip hop choreography in pop culture to give their classes. Well structured class that lacks information on background,history, official terminology.
Why is it so difficult to find the total package?
It's hard to do hip hop justice in a dance studio. If you're abiding by hip hops rules you're almost definitely breaking a standard dance studio rule. The structure of a ballet class would be too restricting to an expressive hip hop dancer. The wild nature of much of this movement requires energy and atmosphere quite different from the normal way of things in a studio setting. How do we make sure our dancers appreciate freestyle in a setting that frequently demands that we pump out choreography? To balance your role as a dance studio instructor with the instruction of proper hip hop elements without doing less of either is no easy task.
Many studios around the country have trouble locking down a professional educator in this genre. So many times we need to throw our hands in the air and say something like, " Well, I guess I'll have to teach the class myself" or " He's not great with the kids but he really knows his stuff." So why do we compromise? Obviously, it's because sometimes we don't have much choice.
So what if you had a choice?
I can help you.
Dance Consultant
Hire A
As a consultant, I keep a regular line of communication open with teachers and dance studios across the country. I have one goal in mind:
rich, educational programs
The many things you'll receive
Choreography analysis
Submit your class videos at any time for feedback on student performance, critiques on dancer technique, and tips on where to go next in the coming weeks or months to see cohesive growth in your program.
Instant access
Introduction phone/skype check-in to discuss your classes, and the option for a mid-year check-in. We cover some hurdles you may be facing as well as new ideas for reinforcement of all the things you wish to accomplish with your dancers.
Availability via e-mail ( Response with-in 24 hours ) or text message ( Response by end of day ) for immediate help.
Music Playlists
Submit requests for new songs, theme ideas, or playlists that fit your needs. To give you an idea, most teachers commonly ask for new warm-up music, breakdancing playlists, popping playlists, & clean music.
Curriculum Assistance
Optional guidance via phone/skype meeting to help you create your full school year curriculum. Please note, crafting a complete curriculum for you is a separate charge.
Exclusive Monthly Articles
Each month, you will receive email articles exclusively for you and other paying clients that detail education and hip hop from a variety of angles. Subjects include tips on boys classes, format, choreography composition, and little known background information on hip hop dance.
Discounts & Free Things
As a consultation client, you will receive a 20% discount on any future purchases of digital material I offer. You may also be entitled to discounts on in person workshops, choreography breakdowns, and much more. Finally, my consultation clients will be welcome to partake in each livestream class I offer throughout the year at no extra cost. As a new live streamed class runs almost every month at a cost of $49.00, the subscription fee for consultation pays for itself immediately.
What does it cost?
$15.00 per month!
That's it! For an individual teacher, when you subscribe to my consultation, you will pay an automatic $15.00 per month for one contracted year. As we cover the entire school year, I'll be assisting in any and all of the things you need, as you need it. During the summer months, I am available to you for your summer class approach ( yes, it should be different ) , workshops you host, things to work on for next season, and more.
Do you want direct help for a group of teachers instead of yourself or an individual?
The above price is designed for one teacher. More than likely, you will not need anything more than what I offer, especially if you are spearheading your studio program and relaying information. However, if you are looking to use this program for multiple teachers running a hip hop program, options for check-ins via skype, call, email, and text message can be made available to all teachers in your program under one subscription. Direct access for a group of people in addition to the standard program perks brings the price up to $25.00 per month. This covers all of the same areas as the individual, with a little extra time given to discuss each of your teachers or consult with them as needed.
Things you should know:
Contracts are made for 1 year, with monthly payments made at the 1st of each month. Current clients use school months for quick advice, music help, technique and terminology, games and exercises. Summer months are generally spent preparing for the next school year and getting tips on summer class focus. Contracts can begin at any point in the year, and can be renewed at the discretion of the customer upon contract expiration.
Once registered, you are given a schedule of hours your consultant is available for response, as well as dates and times for a start-up phone consultation. Off hours (any time that your consultant is not guaranteed for immediate response) will be available for viewing as well. In most cases, your response will come within 24 hours and during the next scheduled office hours. Consultation hours are mostly available on weekdays. Most weekends are not a guarantee for immediate response UNLESS an appointment is made in advance.
Music - You can request music that comes from my playlist, or customize your own ( e.g. "Can I have fun, upbeat warmup music for an all boys pre-teen class?" or " Can you make me a playlist of popping music for teens?" ). Playlist requests can be shared a number of ways. Depending on the preferred method and the details of the request, Playlists may take a couple of days to create and share.
Articles - Via email, each client receives monthly information on hip hop education. Feel free to make requests for future subjects!
Assistance - You may request assistance in choreography analysis, crafting your curriculum, lesson plans and more. Requests can be made for choreography or a custom curriculum, however these come at a separate charge( a client discount will be applied)


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Pro-Light Corner Connector inside; Pro-Light Corner Connector outside Pro-Light Connector; Pro-Light Isolator straight; Brand: Artiteq 110 Sets Tender should reach in the office of the Director, Bihar Museum, Bailey Road, Patna 800 001 on or before 3 PM on 05.09.2017 by Registered/Speed Post only and same will be opened at 3.30 PM in presence of
Working of Solar Street Light. A Battery based Solar Street is a stand alone system, will store electricity from Solar Panels .Solar street lights are powered by photovoltaic panels generally mounted on the lighting structure or integrated in the pole itself. The photovoltaic panels charge a battery, which powers LED lamps during the night.
Sonalika Green Energy India Pvt. Ltd is one of the leading Indian manufacturers of Solar lighting systems. Company based at Patna, in the state of Bihar. Currently we are manufacturing LED Solar Street Light, Flood Light, High Mast Light,Panel light and Solar Water Pump, submersible pump of various sizes and modules. .
Based in Bihar (India), we are one of the leading Manufacturers and Suppliers of LED Light Bulbs. These Light Bulbs are perfectly designed because of which they are known for their durability and longevity. These bulbs consume less power making them high in demand as it saves electricity.
Business listings of Solar Street Lights manufacturers, suppliers and exporters in Patna, सोलर स्ट्रीट लाइट विक्रेता, पटना, Bihar along with their contact details & address. Find here Solar Street Lights suppliers, manufacturers, wholesalers, traders with Solar Street Lights prices for buying.
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BIHAR ELECTRICITY SUPPLY CODE, 2007 CHAPTER 1 GENERAL 1.1 Short Title, Extent and Commencement (1) This Code may be called the "Bihar Electricity Supply Code, 2007". (2) The Code shall come into force from the date of its publication in the official gazette. (3) It shall extend to the whole State of Bihar.
Luminous customer care number in Patna, Luminous Service Centre address, dealers address, contact person, visiting hours and other details are provided below. Luminous offers products like Home UPS, Batteries, UPS, Fans, Solar Power Products, Fans, Wires, Switches and Wires.
SOLAR ENERGY COMPANIES IN AGARTALA - List of Solar Companies in Bihar, Orissa, Assam, Tripura, Agartola, Nagaland - Get the best Deal with BHARAT SOLAR ENERGY - The Leading Solar Brand Company of India. Bharat Solar Energy for solar products & Solar Panels Installation & enjoy our Installation Services across India.
Patna / ˈ p æ t n ə, ˈ p ʌ t-/, also known as Pataliputra is the capital and largest city of the state of Bihar in India. Patna is the second-largest city in Eastern India after Kolkata. [page needed] It had an estimated city population of 1.68 million in 2011, making it the 19th largest city in India.


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Vancouver Anthology : The Institutional Politics of Art (A Project of the Or Gallery)
Douglas, Stan and Wallace, Keith and Diamond, Sara and Shaw, Nancy and Insell, Maria and Wood, William and Williams, Carol and Peck, Robin and Linsley, Robert and Watson, Scott and Crosby, Marcia. Vancouver Anthology : The Institutional Politics of Art (A Project of the Or Gallery). Vancouver, BC: Talonbooks, 1991.
Abstract (English)
Covering the period 1965 to 1990, this anthology of essays examines art in Vancouver, its social and political context, and the conditions of its production. Subjects include artist-run centres, criticism, feminist art, video, film, visual art and the Eurocentric view of Native art. Circa 160 bibl. ref.
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