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Product Description Have you ever considered that when you need a jammer you can find a store that allow you to choose the jamming frequency bands and then do the frequency bands you have selected for you? This is not a dream now and just here this 250W High Power Waterproof OEM Signal Jammer with Omni-directional Antennas that you are viewing here just owns the functions. This 250W waterproof OEM signal jammer is really powerful and can allow you to choose four or five jamming frequency bands among the following frequency bands CDMA, GSM, DCS, PCS, 3G, WiFi, GPSL1, 4G LTE, 4G Wimax, and CDMA 450, in this case people can just tell the four or five jamming frequency bands they want. Thus you can also turn on or turn off the frequency bands according to the real needs as well without affect the jamming functions of other frequency bands at the same time for this OEM signal jammer with Omni-directional Antennas. Thus good cooling fan system and waterproof design has also been used on this 250W waterproof OEM signal jammer as well so that it can easily work outside and also and owning the VSWR circuit protection to ensure system will not burn out should there be antenna short circuiting or disconnection is a merit of this 250W waterproof OEM signal jammer. With such kind of excellent design, for places such as the meeting rooms, prison, museums, training centers, factories and more this high power OEM signal blocker can be widely used. To know more details just come here and seize the chance here. Specifications Affected Frequency Ranges: -CDMA 800: 850 to 894MHz-GSM 900: 925 to 960MHz-DCS1800: 1,805 to 1,880MHz-PCS1900: 1,920 to 1,990MHz (PCS)-3G: 2110 to 2,170MHz -Wi-Fi: 2,400 to 2,500MHz-GPSL1:1570-1580MHz-4GLTE: 700-800MHz-4GWIMAX: 2620-2690MHz-CDMA450: 450-470MHz You can select four or five of above frequency bands you need in a jammer Total output power: 200-250W Jamming range:Up to 300m, the jamming radius still depends on the strength signal in given area External Omni-directional antennas or directional panel antennas ,all the TX frequency covered down link only Power supply: 50 to 60Hz, 100 to 240V AC With AC adapter (AC100-240V-DC27V), Dimension:520(l) x 230(W) x 190mm(H) Full set weight: about 27kg(Used of external Omni-directional antennas) Accessories 250W High Power Jammer Omni-directional antennas Important Notes for Jamming Distance: The jamming distances we mentioned on website are for customer's reference only. The actual jamming distance will be varied depending on the signal strength and the use location and if full charges, etc. Important Notes for Portable Jammers with No Cooling Fan: Do not use the jammer when it is charging, or it will burn the jammer as it has no built-in fan. If because of this factor due to the broken of the jammer, the customer will lose the authority of free repairation .
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Cellular (cell) phones first became widely available in the united states in the 1990s,.


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Macpac Ella Long Sleeve Merino Tee — Women's
Choose size for In store or Click & Collect availability at:
Macpac Adventure Hub Nunawading Change store
Macpac Adventure Hub Nunawading Change store
Why we made this
An ultralight merino long sleeve baselayer providing natural thermoregulation — the Ella range is perfect for travelling and casual wear.
Product Description
A soft merino baselayer, the Ella long sleeve tee is made from 100% merino wool for everyday comfort. Providing natural softness, temperature regulation and odour resistance, merino wool is one of nature's finest fibres. Working to keep you cool in the heat and warm when it's cold, merino wool is highly breathable — absorbing large quantities of moisture vapour before allowing it to evaporate into the air — so you stay comfortable for longer. Grown on the backs of merino sheep, merino wool is a naturally renewable and biodegradable fibre, perfect for casual wear or taking travelling.
Design features
Made from 100% merino wool
Naturally temperature regulating
Merino fibre is odour resistant
Breathable — encouraging the evaporation of moisture
Merino fibre is naturally renewable and biodegradable
Machine washable
Regular fit
Product Specifications
Main Fabric 100% Merino Wool Main Fabric Weight (g/m2) 180 Weight (g) 170 (Size 10)

subset: commoncrawl


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- This event has passed.
Event | FREE
@ The Center: Streaming and Smart TV Lecture
Date & Time
January 17 | 3:30pm–4:30pm EST
Location127 West 25th St
New York,
Every day, more and more people are "cutting the cord" and canceling their cable subscriptions. Instead, they're using free or low-cost streaming services like YouTube, Netflix, and Hulu to watch their favorite shows and movies online. This presentation will give an introduction to streaming: what it is, how to use it, and the variety of content available. You'll also learn how to watch live TV without cable and how smart TVs and streaming devices can let you watch videos from the Internet on your television.
Space is limited! RSVP required. Email firstname.lastname@example.com or call 646-590-0615.


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We are hearing from more and more moms on how they feel about their BENDYs. Most moms don't want to toss out their sense of style when they head out for a day with their wee ones. Dirty sneakers don't make the cut with this crowd. BENDY is part sneaker, part flat and Mom's tell us this blend is a win-win when they have their family in tow.
Olivia Young from Simply Liv and Co shot these precious, family time images over to us from a recent outing. This mom, blogger and influencer is all about Slow Fashion, Tiny Living and Motherhood. Head over to her blog to learn more.
Shop BENDY here


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Poultry Farming Equipment Layer Chicken Cage category
1.Raising egg laying chicken, named layer cage, after pullet growing up to 12 weeks to 16 weeks, it is near adult and starting laying egg, transfer to egg laying chicken cage
2.Rearing baby egg laying chicken, named chick cage or baby chicken cage, from 1 day old to 12 weeks, the feeding trough and drinking line will adjust the height as baby chicken age.
3.Rearing broiler from 1 day old to 45 day after broilers ready for market, named broiler cage, broilers will live in one cage of whole life.
Check my product list to learn different kinds and size of chicken cage
packaging Details
WZH factory chicken cage layer poultry for chicken farm
The cage and frame are nopackage,some fittings are in plastic bags or cartons
1. LCL: first packed with plastic film then on the pallets
2. FCL: Nude packing( 1*20 feet container loading 140 sets,and 1*40HQ container loading 300 sets
3.other special package according to customers' requirements
Delivery Time:
Shipped in 30 days after payment
our company as a Poultry Equipment Manufacturers in China ,if you need that pls contact us.
Copyright © Hebei Weizhengheng Animal Husbandry Machinery Equipment Co.,Ltd All Rights Reserved


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Sunday Morning: Worship Service at 10:00am, Education Hour at 9:00
"Who is Wise?" By Rev. Canaan Harris Posted by The Central Christian Church of Denver on Sunday, January 5, 2020
"Who is Wise?" By Rev. Canaan Harris
Matthew 2: 1-12
In the time of King Herod, after Jesus was born in Bethlehem of Judea, wise men from the East came to Jerusalem, asking, "Where is the child who has been born king of the Jews? For we observed his star at its rising, and have come to pay him homage." When King Herod heard this, he was frightened, and all Jerusalem with him; and calling together all the chief priests and scribes of the people, he inquired of them where the Messiah was to be born. They told him, "In Bethlehem of Judea; for so it has been written by the prophet: 'And you, Bethlehem, in the land of Judah, are by no means least among the rulers of Judah;for from you shall come a ruler who is to shepherd my people Israel.'" Then Herod secretly called for the wise men and learned from them the exact time when the star had appeared. Then he sent them to Bethlehem, saying, "Go and search diligently for the child; and when you have found him, bring me word so that I may also go and pay him homage." When they had heard the king, they set out; and there, ahead of them, went the star that they had seen at its rising, until it stopped over the place where the child was. When they saw that the star had stopped, they were overwhelmed with joy. On entering the house, they saw the child with Mary his mother; and they knelt down and paid him homage. Then, opening their treasure chests, they offered him gifts of gold, frankincense, and myrrh. And having been warned in a dream not to return to Herod, they left for their own country by another road.


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- 2 Show your Support
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Date of Birth July 18, 1924
148 Views
Date of Passing July 29, 2016
Alexander F. Petzinger
from Stockton, California, United States
Alexander Ferdinand Petzinger II, MD passed away on July 29, 2016. He was born on July 18, 1924 in San Francisco. After serving in the Navy during World War II, he graduated from Stanford University in 1949, and Johns Hopkins Medical School in 1956. He worked as an ophthalmologist in Marysville CA, retiring in 1990. He is survived by his brother Richard Petzinger of Stockton, CA and sister Geraldine Helfrich of Redwood City. Alex is also survived by his wife Zoila, his children Erik Petzinger, Giselle Jakowec, Karen Kerwin, Michelle Stivers, and eleven grandchildren. Alex is remembered for being an excellent doctor and a generous person. His family misses him.Send Condolences to www.appealdemocrat.com
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Choose a flower to plant on Alexander's wall
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- Rose
- Gladiola
- Chrysanthemum


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The big picture
New Zealand's fertile, green spaces offer significant opportunities in wood processing and forestry. Sector performance is strong, with products exported around the world, and a growing wood harvest and log supply offers attractive "volume to value" investment opportunities to develop new world-class wood processing operations. Building on this success is a key priority for New Zealand's government, with major long-term initiatives in place to encourage industry growth and support the country's transition to a zero-carbon economy.


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Building and Electrical Materials
We read about fire deaths too many times during any given calendar year. Witnessing this unnecessary pain and suffering in person or through the news media is truly heartbreaking. Most often these fires originate in mobile or permanent homes. read more
2 Holland Way Exeter, NH 03848 United States Tel: 800-301-2701View company website
For more than 165 years, Anvil International has provided quality products combined with the latest ...
3145 Tiger Run Court Suite 105 Carlsbad, CA 92010 United States Tel: 800-854-1015View company website
ARGCO, specializing in marketing to the Fire Protection Industry as well as many other industrial ...
12500 Jefferson Ave Newport News, VA 23602 United States Tel: 909-517-3085View company website
Ferguson Fire and Fabrication (FFF) supplies the highest quality fire-protection products across the United States, ...
229 Southbridge Street Worcester, MA 01608-2045 United States of America Tel: 508-363-4411View company website
Master distributor of valves & fittings. NAPAC, Inc. was founded in 1995, and has proudly ...
2601 Spenwick Dr. Houston, TX 77055 Tel: 713-263-8001View company website
Worldwide Leader in Firestop Technology - Our family of UL approved Metacaulk® Firestopping Products is ...
1675 West Bakerview Road Bellingham, NH 98226 603-418-2800
3170 NASA Street Brea, CA 92621 United States of America 714-999-0323
295 E. Swedesford Road #280 Irwin United States of America 610-783-1498
6307 Toledo Street P.O. Box 2002 Spring, TX 77252 United States of America 713-863-4300
4775 East Cheyenne Ave., Suite 100 Las Vegas, NV 89115 United States of America 702-644-4492


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When you require us, our qualified insurance agents are available 24/7/365 so we're here. You can access your auto insurance policy at any moment by downloading the GEICO Mobile app.
Vehicle Insurance offers protection from losses resulting from owning and also running a lorry. GEICO has actually been helping Americans fulfill their auto insurance needs since 1936. Read GEICO testimonials and also experiences that vehicle insurance consumers have had with client service, asserts handling, insurance rates, and on the internet deals.
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I'm acknowledging Jeannette and also her amazing customer support, mindfulness, competency, and also confidence. With something as difficult as navigating insurance after a scary vehicle mishap, it was so alleviating to chat it via with her. She is entitled to all the appreciation.
I have actually been with another insurance provider for near to 20 years. I never ever doubted increases until my boy started driving. WOW what a shock Cameron provided me at the Daytona workplace. I will not be conserving close to a $100 each month. I have 3 automobiles so you can see what a multi automobile price cut can do for you. Next we are mosting likely to check out boat and also house insurance. I can not comment on claim services yet.


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Use your computer to play Samurai Showdown. Or try one of the games below!
Samurai Showdown
Samurai Showdown is a unique and engaging fighting game involving legendary Samurais. An evil group of Samurais has emerged who want to overthrow the kingdom and cause havoc throughout the land. It is your duty as a true Samurai to uphold the Bushido Code and bring them to justice!
- WASD or arrow keys to move
- Left or right click to attack
- E to interact
- F to roll
- P to open menu


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Recent Posts
I'm busy working on my blog posts. Watch this space!
Featured Posts
I was so excited to be asked to make a Harry Potter themed shoe for a client who was attending a Harry Potter themed wedding in November this year.
The most amazing part of this project was that she had given me full creative control, even down to the colour of the shoe. Her only stipulation was that the shoes needed to have a pointed toe and a golden snitch on the back.
The shoes I decided to use were a metallic silver with a slightly higher back, a great colour and shape for Harry Potter themed shoes. I started by covering the shoes in writing and symbols down both sides of the shoes. The outer shoe featured the words 'I solemnly swear that I am up to no good' and the inner side detailed the Deathly Harrow sign and Harry Potter spectacles. I then hand painted tiny white stars with swarovski crystals all over the shoes including the heel.
For the front of the shoe I made a tiny spell book, a miniature wand and small 'Daily Prophet' newspaper. As my client had requested, I made her a golden snitch out of clay and feathers for the back of shoe. On the underside of shoe I stamped a red Hogwarts seal of approval!
These shoes were a treat to make and she absolutely loved them and so did I! I was slightly upset when they went away as they are definately one of my favourite creations!


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Tagged: jdm
rocket bunny wheels
I am pretty excited about these. I love mesh style wheels, and I love having the options of running smaller diameter wheels on my E36 or E90 even (I want 18's next for performance reasons and better performance tire options). They are made by Enkei for RocketBunny 6666 and will be offered in custom sizing and pcd from 16 to 18 inches and 100 – 130 pcd.
babyface & scarface
kenny chow
This is my friend Kenny Chow's Corolla wagon. I've known this guy for several years now. The wagon has always been cool, but it has gotten cooler and cooler over the last couple of years. It sat in his driveway for quite some time due to electrical problems. It's one of those cars that pushes me to continue being original with my projects.
Toyotafest the Old School
Legend of Tsukuba


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If you're looking for paving slabs or patio slabs, you needn't look any further than Huws Gray - because we have a huge range of great products at low prices. We offer a combination of choice, value and quality you won't find anywhere else - and that's what keeps so many people coming back to us time and time again. Because we bring so many great deals on patio and paving slabs together in the one place, we can help save you time and effort as well as money. Take a look at our selection of garden paving to find out just what's on offer at Huws Gray.


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Events for March 17, 2020
Events Search and Views Navigation
All Day
Eco March Break Camp
Have you ever wanted to learn more about the natural world around you? Do you want to learn ways to reduce your carbon footprint? Do you love spending time outdoors? This camp may be for you! Join us this March Break as we learn about how to better care for the earth in fun and...Find out more »
March break craft workshop
March Break Activity CRAFT WORKSHOP at the Creating Centre in Vankleek Hill March 16 – 17, 1 – 4 pm TRADITIONAL SALT DOUGH FOLK ART $20. All ages welcome. Full day camp available. Stephy Pete 613-854-5226Find out more »


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Upcoming Events
There are no upcoming events at this time.
Category Archives: Congress 2017
Welcome to the Violence and Society Research Cluster
Many argue that we live in a violent society. Indeed, people from all walks of life are subject to many forms of violence. We are bombarded daily with information and images that continually remind us about the potential threat of … Continue reading
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text: REVIEW ARTICLESBiomedical ontologies and their development, management, and applications in and beyond ChinaPan, Hongjiea; Zhu, Yanb; Yang, Shenga; Wang, Zhiganga; Zhou, Weic; He, Yongqund; Yang, Xiaolina,*Author Information aInstitute of Basic Medical Sciences, Chinese Academy of Medical Sciences (CAMS) & School of Basic Medicine, Peking Union Medical College (PUMC) bInstitute of Information on Traditional Chinese Medicine, China Academy of Chinese Medical Sciences cNational Scientific Data Sharing Platform for Population and Health, Beijing, China dUniversity of Michigan Medical School, Ann Arbor, MI, USA. Corresponding author: Xiaolin Yang, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences (CAMS) & School of Basic Medicine, Peking Union Medical College (PUMC), Beijing, China. E-mail: email@example.com. Received September 9, 2019 Accepted October 25, 2019 Online date: November 22, 2019 This is an open access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (CCBY-NC-ND), where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially without permission from the journal. http://creativecommons.org/licenses/by-nc-nd/4.0 Journal of Bio-X Research: December 2019 - Volume 2 - Issue 4 - p 178-184 doi: 10.1097/JBR.0000000000000051 Open Metrics Abstract Since the boom of biomedical big data studies, various big data processing technologies have been developed rapidly. As an important form of knowledge representation, ontology has become an important means for the utilization and integration of biomedical big data. The emergence of new technologies for ontology development has resulted in the generation of many biomedical ontologies by many ontology development communities. The Open Biological and Biomedical Ontology Foundry, an academic organization for bio-ontology developers, has provided a set of principles to guide community-based open ontology construction. The Open Biological and Biomedical Ontology Foundry have also built many widely used ontologies, such as Gene Ontology, Human Phenotype Ontology, and Chemical Entities of Biological Interest. Other various ontology repositories have also been created and used to support ontology reuse. Many efficient tools for ontology applications, such as data annotation and terms mapping, have also been developed. High quality ontologies are also being used to develop new methods and tools for biomedical data analysis. The applications of Gene Ontology and Human Phenotype Ontology for data analysis and integration in recent years are reviewed here. To promote the development and applications of biomedical ontologies in China, a research community, OntoChina, was founded recently. OntoChina aims to support the development of reference ontologies, especially bilingual and Chinese translated ontologies. OntoChina also encourages ontology developers to follow the Open Biological and Biomedical Ontology Foundry principles. A quick glimpse of the ontology framework Ontology, historically, was used to describe a branch of philosophy in ancient Greece, which was concerned with the study of nature and relations of being.[1] In modern computer science, the word has been borrowed to refer to a common, controlled knowledge representation designed to help knowledge sharing and computer reasoning in a specific domain.[2] Specifically, an ontology is a set of terms to represent entities, and a set of relations to specify the semantic relationships between those terms in a specific domain; and those terms and relationships should be computer- and human-interpretable. Currently, World Wide Web Consortium (W3C) Web Ontology Language (OWL) is the most predominant used language for ontology. Ontologies can be divided into three types from the perspective of application. The first type is upper ontology, also called top-lever ontology, which provides a common framework for defining and structuring the terms and relations in a specific domain.[2] Commonly used upper level ontologies include Descriptive Ontology for Linguistic and Cognitive Engineering) (DOLCE),[3] Suggested Upper Merged Ontology (SUMO),[4–6] CYC upper ontology (CYC),[7] General Formal Ontology (GFO)[8] and Basic Formal Ontology (BFO).[1,9] Another type is reference ontology (domain ontologies), which represents the terms and their relationships in a specific domain. For example, Disease Ontology (DOID)[10] and Human Phenotype Ontology (HPO)[11] are widely used domain ontologies. The third type is application ontology, which is developed for a specific scenario or application and provide a minimal terminological structure to fit the limited needs.[12] In the recent decades, ontology has been widely used in the biomedical area to help solve the issue of data heterogeneity, leading to advanced data analysis, knowledge organization and reasoning. Database search strategy The author used the following criteria or procedures to retrieve related literatures: (i) a general search of ontology development within 2000 and 2019 was performed, mainly using the Google Scholar and NCBI database and Google server, and focused on ontology development and application; (ii) to narrow down the coverage to find ontology used in biomedical field, a further search using key words "ontology" and "biomedical", "clinical" was utilized and have a preliminary understanding of biomedical ontology; (iii) and the result were screened with additional terms "resource" and "repository" to find some centralized ontology portals to have a comprehensive vision of biomedical ontology groups and the supported communities; (iv) similarly, the former processes were also applied in domestic academic literature search via Baidu server and some related academic databases in China to find related domestic built ontology resources. Ontology, biomedical big data, and precision medicine Since the National Aeronautics and Space Administration, U.S. scientists Michael Cox and David Ellsworth first proposed the forthcoming challenge of big data in 1997,[13] the idea of big data has rapidly penetrated into all corners of the world, and it has had an influence in all fields of natural science, social science and engineering.[14] In the biomedical domain, with the rapid development of new technologies such as the completion of the Human Genome Project and high-throughput sequencing, a large amount of biological data has been generated, including genomics and proteomics, and clinical medicine data. Precision medicine,[15] also known as personalized medicine, is a new medical concept and medical model with the aim of achieving individualized medicine, which relies on the integration of data from diverse sources,[16] including multi-omics, electronic health records and even wearable devices. However, the huge heterogeneity in these biological data has greatly impeded data harmonization and integration of precision medicine. Therefore, an effective and efficient precision medical decision system requires advanced data analysis, knowledge organization, representation and reasoning. Ontology plays a pivotal role in precision medical data organization and application. First, ontology provides a terminology framework to reduce data heterogeneity and allows data to be interoperable between biomedical information systems. Through the process of data annotation by biomedical ontologies, data and the description of metadata are coded by a unique ID and its corresponding label. For example, the terms in HPO can be used to standardize a patient's symptoms and signs. DOID can be used to represent the diagnosis results. As for metadata standardization, Ontology for Biomedical Investigations (OBI)[17] provides a formal representation of the content of metadata types. As a result, it not only clearly specifies the concepts of metadata, but also describes the relationships between them. In this way, semantic heterogeneity from biomedical information systems can be reduced to ensure interoperability, and automatic data integration, analysis pipeline and some extensible data analysis method-based reasoning can be realized more easily. Ontology can help to form precise and useful classification required for individualized medicine. Classifications describe entities from domains of interest, such as diseases, phenotypes, medications, and exposures, by naming the entities in each domain and providing computational specifications of diverse degrees of sophistication.[18] In ontology, the most important relationship is the 'is_a' relation, which is used to construct the basic hierarchy. Beyond that, ontology also specifies other logic relationships between entities, such as 'has phenotype' (RO_0002200) relationship, which is mainly used to describe a disease inhering in an organism, then the organism has a phenotype. Figure 1 shows how a disease is represented by DOID. A term for disease can have multiple parents and disease related factors, such as etiology, genetic mutation, phenotype, and location of the disease are expressed in a descriptive logical way. Thus, a multiaxial classification is established that defines a patient with a more accurate and deeper classification, which also provides a computable framework for further data analysis.Figure 1: The representation of tyrosinemia type II in Disease Ontology (DO). This figure shows the ontological presentation of a disease node/term and its related nodes/terms in DO disease. Different colors represent different semantic relations between the center node (red block) and the pointing nodes (blocks in various colors except the red block).Ontology also provides formal knowledge representation required for medical decision support, whereby clinicians, staff, patients, or other individuals can use this knowledge and person-specific information, intelligently filtered or presented at appropriate times, to enhance health and health care.[19] In such a system, a central task is how to develop a reasoning system and specify the knowledge on which the reasoning system can operate. In an ontology-driven clinical decision support system, the key concepts and relationships from clinical practice guidelines, a source of evidence-based knowledge, are formalized in ontologies to ensure knowledge sharing, integration, and reuse. In Assessment and Treatment of Hypertension: Evidence-Based Automation - Clinical Decision Support,[20] an automated clinical practice guideline-based clinical decision support system, a general guideline ontology was generated to define how to represent a guideline, which can then instantiate the ontology to build a knowledge base for a specific disease or disease condition. Then a problem-solving program combines the knowledge base with individual patient data from electronic health records to determine whether the patient is eligible for treatment in accordance with the guideline.[21] Ontology resource open sharing In the past 2 decades, the range and diversity of ontologies have increased dramatically. The demand for ontology reuse, data integration and annotation, as well as ontology alignment has led to the development of specialized ontology repositories. The most well-known biomedical ontology resource repositories are National Center for Biomedical Ontology (NCBO) BioPortal,[22,23] Ontobee,[24] Ontology Lookup Service (OLS)[25,26] and AberOWL.[27–29] These ontology repositories provide many tools for ontology. Table 1 lists these repositories and their ontology application tools. For example, Ontology Lookup Service OxO and NCBO BioPortal Annotator are data annotation tools that annotate natural language using ontology terms and thus semantic standardization can be realized. Linked data services have been a recent research hotspot, although difficulties in ontology online representation exist. One of the important principles of linked data is to provide valid data for Uniform Resource Identifier (URI) when indexed,[30] especially to show the meaning of a single term through the URI of the ontology term. NCBO BioPortal proposed a way of dereferencing ontology terms by using the Persistent Uniform Resources Location (PURL) server to redirect the ontology term to a permanent html page. However, the user still cannot directly use the URI of the term to dereference a real web page and obtain a corresponding Resource Description Framework (RDF) file. To accomplish the conversion to linked data, He's Group[31] created a terminology dereference model in Ontobee that is different from other methods. In this model, all ontology triples are stored in the Virtuoso triple store, SPARQL queries are submitted to the triple store via PHP, and the returned SPARQL query results are stored in the JSON format and as an OWL file for the term. Ontobee converts JSON to an HTML page via PHP and embeds the resulting HTML page link in the OWL file via Extensible Stylesheet Language Transformations (XSLT) technology. When the browser accesses the corresponding ontology term URI, the html page and the OWL file are simultaneously acquired, and the display of the HTML page and the OWL file content in the source code of the page are realized. Therefore, Ontobee realizes the deference of the ontology term URI, and is a real ontology linked data server. It is the default linked data server for the Open Biological and Biomedical Ontology (OBO) Foundry.[32,33]Table 1: Ontology resources repository.To provide diverse ontology services, several ontology libraries have been constructed by using the technology framework mentioned above. Among them, the French AgroPortal ontology resource repository, based on NCBO BioPortal architecture, is dedicated to the construction of multilingual ontology resources in the fields of agronomy and related domains, and adds new external ontology term mapping information and new metadata services. The ontology resources in AgroPortal cover the contexts in six languages including English and French.[34–39] MedPortal, created in China, is also based on the NCBO BioPortal framework and is used in the biomedical field.[40] It now stores 55 ontology resources, covering both Chinese and English language environments, aimed at meeting the needs of domestic Chinese users for international high-quality ontology terms and Chinese translation ontology terms. In addition, ontology resources and tools mirrors, such as Ontobee and Ontofox[41] are also used in China to satisfy the needs of domestic ontology development and application. Community-based ontology development With the proliferation of ontology, heterogeneity and redundancy have become big problems in ontology development. A traditional approach to solving these problems is to build retrospective mapping based on synonymy relations.[32] However, this method introduces new errors and confusion to the ontologies. Therefore, the OBO Foundry, as an internationally recognized ontology developer community, advocates a new strategy to build community-based biomedical ontologies based on a specific set of principles.[32] The OBO Foundry established community-based ontology development principles for life science, mainly encompass open use, non-overlapping and strictly-scoped content, collaborative development, common syntax and relations, and more details can be viewed online (http://www.obofoundry.org). Under the guidance of these principles, OBO ontologies have been formed more logically, and are interoperable, accurate, easily reused and with less redundancy. As of September 2019, 10 mature ontologies have passed the OBO Foundry principles and are recommended as preferred targets for community convergence. The other 149 ontologies are candidates and require further updating and verification. According to the results from an analysis of ontology reuse in NCBO BioPortal in 2017, content from OBO ontologies are most widely reused by other ontologies for the purposes of creating new ontology content.[23] To disseminate the OBO principles and promote the quality of biomedical ontologies in China, the China Biomedical Ontology Joint Working Group (OntoChina, http://www.ontochina.org) was established in October 2017 with support from NCMI (China National Population Health Data Sharing Platform).[16] Based on the OBO principles, one primary task for OntoChina is to build English-Chinese bilingual ontologies or Chinese translation ontologies based on the original English reference ontology. OntoChina is also committed to building a comprehensive informatics framework to support ontology development and ontology-based applications. OntoChina has become an interactive and collaborative community devoted to ontology research in and beyond China. A miniature of biomedical ontology application Currently, ontology has become an important solution to the biomedical big data issue. Here we will provide an overview of some successful applications of biomedical ontology. Ontologies make science data more Findable, Accessible, Interoperable and Reusable (FAIR) In 2016, the Future of Research Communications and e-Scholarship community (FORCE 11) introduced a fundamental principle for scientific data management and stewardship, termed FAIR, which highlights criteria that the open science data should reach.[42] One principle of FAIR is how to represent metadata in a manner that machines and humans can process. Ontology provides logical definitions and relationships for metadata to enhance interoperability between different metadata systems.[16] OBI provides terms with precise definitions to describe metadata types of how investigations in the biological and medical domains are conducted.[17] Dugan et al[43] established a standardized metadata system for human pathogen genome sequences based on OBI to maintain a consistent representation of data from different projects or institutes. Gonçalves et al[44] set up the Center for Expanded Data Annotation and Retrieval (CEDAR) workbench to create a biomedical metadata construction process that provides a template designer, metadata editor tools, and a metadata repository to provide technology support for building and storing users' metadata templates. The workbench encapsulates the NCBO BioPortal API, providing ontology standard vocabulary support for metadata creation.[44] Several software programs were developed to support the process of semantics standardization. The Investigation-Study-Assay (ISA) software suite helps users to utilize all types of data standards (Minimum reporting guidelines, terminologies and formats) in life science to provide rich and interoperable descriptions of the experimental metadata.[45] OntoMaton, a tool in ISA and a plugin on Google Sheet, facilitates ontology searches and then annotates experimental data by ontology terms through NCBO BioPortal API.[46] Furthermore, to facilitate online metadata curation in an online database, a browser extension, CEDAR OnDemand powered by the NCBO BioPortal, enables users to seamlessly enter ontology-based metadata through existing web forms of the native database systems.[47] Of note, data scientists, domain experts, and software developers should work together to create an environment where data standards are easily found and can be used by experimental data collectors, which is the first step to data FAIR. Gene Ontology (GO) and GO annotation GO is likely the most successful ontology. Since it was established 20 years ago, it has boosted bioinformatics database construction and data analysis. GO describes the functions of gene products across all species in a consistent and computer-accessible manner using a controlled vocabulary and logical relationship that facilitates the integration of public biological data.[48,49] In GO, the gene product function covers three distinct aspects: molecular function (the activity of a gene product at the molecular level), cellular component (the location of a gene product's activity relative to biological structures), and biological process (a larger biological program in which a gene's molecular function is utilized).[48,49] GO annotation, an international collaborative project, was initiated to provide high-quality electronic and manual annotations to individual gene products from specific species using the standardized vocabulary in GO[50]. Thus, the relationships between specific gene products and GO terms are constructed. Consequently, a GO knowledge base was formed, in which an annotation is represented in a "triple" format: UniProtKB:P04637 "involved in" GO:0045944. Here, UniProtKB:P04637 denotes the cellular tumor antigen p53 for Homo sapiens and denotes the process of positive regulation of transcription by RNA polymerase II. Furthermore, the curator can assign an evidence code from the evidence and conclusion ontology[51,52] to a GO annotation so that the user can assess the correctness of the annotation. The GO knowledge base has had a significant impact on bioinformatics data analysis. The most widely used GO-based method is GO enrichment analysis, which is used to identify enriched functions of a list of given genes.[53] The generation of multilayers of biological complexity in computational function annotations also raised the question of prediction performance in reflecting biological reality. Indeed, some evaluation mechanisms have been used to improve the prediction effect.[52] In 2017, the GO consortium provided a new annotation model, GO-Causal Activity Modeling,[54] which represents a detailed semantic model of how one or several gene products contribute to the execution of a biological process. Although the GO-Causal Activity Modeling data is currently limited, it will promote new data analysis methods based on the GO knowledge base. HPO and rare disease diagnosis The HPO is committed to the collection and integration of standard terminology and disease annotation information for human disease phenotype abnormalities to enable large-scale disease phenotype computer analysis.[11] The contents come from databases and medical literature such as Orphanet,[55] DECIPHER,[56] and Online Mendelian Inheritance in Man (OMIM),[57] covering more than 10,000 clinically abnormal phenotypic terms and over 50,000 genetic disease annotations. In clinical data, abnormal phenotypic terminology in HPO can be used to diagnose human diseases. However, the relationships between genes and phenotypes have been built up and recorded in many databases. Therefore, phenotypes can be used as a bridge to infer the relationships between genes and diseases. Phenotypic Interpretation of eXomes (PhenIX), a computer disease diagnosis tool based on HPO data developed by Zemojtel et al,[58] can sort the variant sites obtained by sequencing and select the mutations most likely to cause diseases, as well as assist clinicians in disease diagnosis. Because of the weakness of simple term-matching in identifying diseases in non-ontological presentations of features in syndromes by different physicians, the Ontological Similarity Search has been used to find a "good match" in syndromes or disease by ranking the similarity scores of terms related to the presentation.[59] The Ontological Similarity Search with P values can further improve the Ontological Similarity Search analysis, resulting in the identification of the "best match" in disease. The application Phenomizer has implemented the Ontological Similarity Search-PV online to assist physicians in the diagnostics of human genetics.[59,60] Additionally, to promote the utilization of HPO in non-English speaking countries, many countries have translated the source HPO into a domestic version, such as the Chinese version of the CHPO database (http://www.chinahpo.org/#), aimed to promote rare disease research in China. Challenges and ontology development in China The development of biomedical big data has promoted the open sharing of biomedical ontology and the development of the OBO Foundry, and therefore the number of open and shared ontologies has increased rapidly in recent years. The open sharing of biomedical ontology resources in turn promotes the reuse of ontology resources and the development of new ontology resources in biomedical big data integration. For ontology curators or developers, the reuse of ontology terms reduces the complexity of the review process for new terminology. But this also brings some new problems to curators and users. First, it is difficult to determine the degree of reuse of existing terms[23]; that is, either to choose to reuse the entire ontology or part of the ontology module.[61–63] Second, it is unclear how to keep the reuse term with the version control of the source ontology, especially for terms in partial module reuse. Version control is relatively cumbersome. Last, developers may be confused on the choice of the top-level framework of the ontology. Should they choose the top-level framework design pattern recommended by OBO or choose the ontology framework that is most suitable for the field? Such a decision is required to be discussed before ontology construction. In addition, as shown in Table 2, we analyzed the statistics of the distribution of ontologies in 4 repositories, ie, NCBO BioPortal, Ontobee and OLS, and AberOWL. Overall, there are 141 ontologies stored in the four repositories. In many cases, the same ontology between ontology resource repositories has no version control or the source is unknown. The ontology developer or user needs to manually discriminate the version to obtain the final desired ontology. These issues need to be discussed and resolved by the OBO Foundry and/or other ontology communities.Table 2: Ontologies stored in more than one repository.Additionally, the development of biomedical big data has promoted the demand for multilingual ontologies. Biomedical big data, especially clinically related data, often are recorded in native languages. However, existing bio-ontologies are mostly written in English. It is often necessary to translate the corresponding ontology standard or database to form a local language copy to be able to apply the ontology. For example, in France, Japan and other countries, the translation of the International Statistical Classification of Diseases and Related Health Problems 10th Revision (ICD10) ontology terms has been completed successfully. The OBO Foundry also suggested that a multi-language ontology should be constructed. In the past 2 years, OntoChina has translated several OBO ontologies into Chinese and built OWL files for multi-language ontologies, such as the Cell Line Ontology (CLO),[64] and OBI and BFO. As an advocate for the Chinese translation of high-quality English ontologies and OBO Foundry, OntoChina will continue to promote the construction of Chinese translations of high-quality middle-level ontologies and their corresponding ontology applications in the near future. Acknowledgments None. Author contributions HP and XY designed and drafted the manuscript. YH, XY and YZ supervised and wrote the manuscript. All authors revised the manuscript and approved the final version of the manuscript. Financial support This work was supported by Chinese Academy of Medical Science (CAMS) Innovation Fund for Medical Sciences (CIFMS) (No. 2018-I2M-AI-009 to XY), Independent Subject Project Funded by Basic Scientific Research Fund of Chinese Academy of Chinese Medical Science (No. zz110318 to YZ) and the University of Michigan Global Reach Award (to YH). Conflicts of interest The authors declare that they have no conflicts of interest.References [1]. Arp R, Smith B, Spear AD. Building Ontologies with Basic Formal Ontology. Cambridge, USA: MIT Press; 2015. Cited Here [2]. Robinson PN, Bauer S. Introduction to Bio-Ontologies. Boca Raton, USA: CRC Press; 2011. Cited Here [3]. Gangemi A, Guarino N, Masolo C, et al. Sweetening ontologies with DOLCE. Knowledge Engineering and Knowledge Management: Ontologies and the Semantic Web. Berlin, Heidelberg. 2002. Cited Here [4]. Pease A. The suggested upper merged ontology: a large ontology for the semantic web and its applications. 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Cited Here [51]. Chibucos MC, Siegele DA, Hu JC, et al The Evidence and Conclusion Ontology (ECO): supporting GO annotations. Methods Mol Biol 2017;1446:245–259. Cited Here | PubMed [52]. Dessimoz C, Škunca N. The Gene Ontology Handbook. New York, USA. 2017. Cited Here [53]. Mi H, Muruganujan A, Huang X, et al Protocol Update for large-scale genome and gene function analysis with the PANTHER classification system. Nat Protoc 2019;14:703–721. Cited Here [54]. Balhoff JP, Good B, Carbon S, et al. Arachne: an OWL RL Reasoner Applied to Gene Ontology Causal Activity Models (and Beyond). International Semantic Web Conference. Monterey, CA, USA. 2018. Cited Here [55]. Rath A, Olry A, Dhombres F, et al Representation of rare diseases in health information systems: The orphanet approach to serve a wide range of end users. Hum Mutat 2012;33:803–808. Cited Here | View Full Text | PubMed | CrossRef [56]. Firth HV, Richards SM, Bevan AP, et al DECIPHER: Database of chromosomal imbalance and phenotype in humans using ensembl resources. Am J Hum Genet 2009;84:524–533. Cited Here | PubMed | CrossRef [57]. Amberger JS, Hamosh A. Searching Online Mendelian Inheritance in Man (OMIM): a knowledgebase of human genes and genetic phenotypes. Curr Protoc Bioinformatics 2017;58:1.2.1–1.2.12. Cited Here [58]. Zemojtel T, Köhler S, Mackenroth L, et al Effective diagnosis of genetic disease by computational phenotype analysis of the disease-associated genome. Sci Transl Med 2014;6:252ra123. Cited Here | PubMed | CrossRef [59]. Köhler S, Vasilevsky NA, Engelstad M, et al The human phenotype ontology in 2017. Nucleic Acids Res 2017;45:D865–D876. Cited Here | PubMed | CrossRef [60]. Köhler S, Schulz MH, Krawitz P, et al Clinical diagnostics in human genetics with semantic similarity searches in ontologies. Am J Hum Genet 2009;85:457–464. Cited Here | PubMed | CrossRef [61]. Stuckenschmidt H, Parent C, Spaccapietra S. Modular ontologies: concepts, theories and techniques for knowledge modularization. Berlin: Springer; 2009. Cited Here [62]. Doran P, AM, Tamma V, Iannone L. Ontology Module Extraction for Ontology Reuse: An Ontology Engineering Perspective. New York: ACM; 2007. Cited Here [63]. Grau BC, Horrocks I, Kazakov Y, et al. Just the right amount: extracting modules from ontologies. Proceedings of the 16th international conference on World Wide Web. Banff, Alberta, Canada. 2007. Cited Here [64]. Ong E, Xie J, Ni Z, et al Ontological representation, integration, and analysis of LINCS cell line cells and their cellular responses. BMC Bioinformatics 2017;18:556. Cited Here | PubMed | CrossRef Keywords:biomedical big data; community-based; ontology; ontology-based application; open sharing Copyright © 2019 The Chinese Medical Association. Published by Wolters Kluwer Health, Inc.View full article text


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IIIEE Library
The International Institute for Industrial Environmental Economics (IIIEE) Library
Welcome to our new website, which is under construction to better serve you!
If you have any questions, please contact the library at library [at] iiiee [dot] lu [dot] se.
/Library Staff
Page Manager: Library [at] iiiee [dot] lu [dot] se
30 January 2020


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Top 22 Funny Memes about Mom Life
Moms life is the toughest life on Earth. You have to work 24 hours without even getting paid for it. You have to fully dedicate yourself to your family and your all time belongs to them which means no more personal time for you at all. Here are some of the memes for moms life dedicated to all the moms who are dedicating themselves to their families. So lets enjoy some memes.


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Meet The Team- Nantwich
Meet The Team- Nantwich Clinic
Located in a traditional black and white building on the prestigious Welsh Row in Nantwich town centre of Cheshire. There are Six treatment rooms positioned over multiple floors, a large reception/retail area plus two waiting areas this clinic is the cosmetic equivalent of the tardis! In addition to the extensive range of aesthetic treatments, the clinic also offers indulgent massage, traditional beauty services and colonic hydrotherapy. Meet the team that who keep your skin and clinic in tip-top shape!
Stacey- Assistant Manager
I have been working for skin health spa since 2012, I started as a trainee Aesthetician and I have worked my way up to become assistant manager. I can't believe I've been here 6 years time flys when you're having fun!! :-)
Favourite Treatment
Favourite treatment? It's hard to pick a favourite treatment as I love them all. For me, laser hair removal has been amazing. I use to get ingrowing hairs from waxing and shaving was a pain, now I don't have to worry about either! It's also really rewarding to see my clients getting the same results and loving the laser as much as me!
Favourite Product
I'd say my favourite product is our 12% glycolic cleanser. I use this before bed it leaves my skin squeaky clean, giving it a deep cleanse without causing dryness. Glycolic has lots of great benefits for your skin it helps reduce pores, dissolves dead skin cells leaving you with fresher brighter skin! What's not to love!
Rebecca- Senior Aesthetician
I have been working in the beauty industry since passing college in 2010. Moving over to the aesthetic industry with skin health spa in 2014 has been nothing but a pleasurable and rewarding move stepping away from the ordinary beauty treatments and into the aesthetic industry. I love being an Aesthetician and providing results for my clients.
Favourite Treatment
My favourite treatment we offer at the moment is collagen pin as it treats all skin concerns from scaring to stretch marks or for general skin rejuvenation and I've had some fabulous results with it.
Favourite Product
My favourite product is the 12% glycolic evening cleanser. This is great for clients of all ages and concerns to be using at home between visits. Glycolic is a great anti-ageing acid & great for blackheads too!
Becky- Senior Aesthetician
I have been working for Skin health spa for 5 years now and in the industry for 8. I am passionate about my job because we always have the most up and coming treatments and this enables me to keep my knowledge up to date. The atmosphere in the clinic is always happy and positive and I'm lucky to be part of such a great team.
Favourite Treatment
My favourite treatment is the Crystal Clear COMCIT facial because results are visible after one treatment and it's also relaxing.. bonus!!
Favourite Product
My favourite product is the Flint plus Flint SPF30 Primer as this is not only protecting my skin but is also a primer to help my makeup go on smooth and pores look minimised.
Kirsten- Aesthetician
I have worked in the beauty industry since 2012 working in department stores and spas before pursuing my passion for Aesthetics. I really enjoy the results that clients can see on their skin from the treatments we offer and the confidence it gives them.
Favourite Treatment
My favourite treatment is a Micropeel, this includes our popular microdermabrasion treatment for the removal of dead skin and a brighter complexion followed by a skin peel that can be adapted to the client's skin type.
Favourite Product
My favourite product is the Flint plus Flint serum. I have quite dry skin and so this really helps to hydrate without feeling too heavy. I can see a big difference in the brightness of my skin after using this product.
Vanessa- Front Of House
Working at skin health spa for the past 2 years has been a fascinating experience. I am continuously interested in the next best thing with regards to skin and beauty, so being front of house really gives me an insight into all the state of the art treatments we offer.
Favourite Treatment
My favourite treatment is the Mesoestetic salicylic peel. It allows you to gain back control from having oily congested skin and leaves a smooth clear fresh base for a natural look, other benefits include reduced pores and clears up acne-prone skin, a major hit with the young adults who have stressed out skin and breakouts.
Favourite Product
My go-to product is the SPF primer from our flint plus flint range. We can't have a client leave without it after laser & yes they do return if they're running low. It works wonders for make-up application and very ideal for your holidays, 2 in 1 … Bonus!
Want to know more? Then please feel free to pop in and book a FREE skin consultation and skin analysis with any of the members of team
Call: 01270 613890
Email: [email protected]
Social: @skinhealthspa


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Kathy A. "Sweetie" Van Kirk, 64, of Martins Ferry, OH passed away January 20th, 2020 at her home surrounded by her family.
She was born October 24, 1955, in Martins Ferry, a daughter of the late Kenneth and Vera Mae (Graham) Reeb.
Kathy was a retired staff member of 23 years at Yourkovich and Associates and was a Christian by Faith. She was an avid bowler and was a member of the USBC.
In addition to her parents, she was preceded in death by a brother, Eugene "Sonny" Reeb, and grandmother, Mary Graham.
Kathy is survived by her husband, Robert "Bubba" Van Kirk; sons, Kenny (Laura) Morrison of Bridgeport, John (Manda) Morrison of St. Clairsville; sisters, Cheryl Horne, Cindy (Rich) Bickerstaff, Becky (Randy) Baker all of Martins Ferry; grandchildren, Corey, Codey "Bear," Devin "Buck," Cheyenne, Lexi and Sarah Morrison; nine nieces and nephews, and many great-nieces and nephews.
Friends will be received Thursday, January 23, 2020 from 2-4pm and 6-8pm at Wilson Funeral Home, 920 National Rd., Bridgeport, OH where funeral services will be held Friday, January 24th at 11a.m. with Pastor John Cook officiating. Interment to follow at Holly Memorial Gardens.
In lieu of flowers, memorial contributions can be made to St. Jude Children's Research Hospital in her name at stjude.org or 262 Danny Thomas Place, Memphis, TN, 38105.
To offer online condolences visit wilsonfuneralhomes.com.
To send flowers to the family or plant a tree in memory of Kathy Ann (Reeb) Van Kirk, please visit our floral store.
St. Jude Children's Research Hospital
501 St. Jude Place, Memphis TN 38105
Tel: 1-800-805-5856
Web: http://www.stjude.org/


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