text:
Brooklyn, NY Bestreich Realty Group (BRG) closed the sale of 264 Jefferson St. in the Bushwick neighborhood. This multifamily sold for $1.05 million, which equates to $245 per s/f.
The building features six two-bedroom apartments totaling 4,290 s/f. It sits on a 25 ft. x 100 ft. lot and zoned R6, C1-3. The property was sold with five rent stabilized units and one vacancy after the Housing Stability and Tenant Protection Act 2019 was enacted.
Steve Reynolds, Derek Bestreich, Tom Reynolds, and Brian Davila facilitated both sides of the transaction. The seller was in the Estate of Frank Prestigiacomo and the buyer was Tiger Property Partners LLC.

subset: commoncrawl


text:
October 2, 2019 2 Comments
oil pipelines and financial plumbing pdf
PROFITS BY INDUSTRY Q2 2019 (Spreadsheet)
This WordPress.com site is dedicated to independent working class politics. Contact me at email@example.com
October 2, 2019 2 Comments
oil pipelines and financial plumbing pdf
PROFITS BY INDUSTRY Q2 2019 (Spreadsheet)
Filed under Uncategorized
Rich in information and analysis. Thank you.
"huge losses that followed the reverse in sovereign interest rates earlier in August when 10 year yields rose 0.25%". Wasn't it closer to 0.5%?
"cash rich banks are reluctant to lend to them even against high quality collateral. "
The quality of the collateral is debatable. The sharp rise in 10 year yield in one week by .5% caused sharp drop in the value of the collaterals. The sudden and sharp fluctuations in yields makes US Treasuries risky collaterals. It is possible that the cash rich banks were expecting 10% fluctuations in the value of collaterals. My guess is that that's were the 10% interest came from but then I am speculating. The second reason is that the same collateral (U.S. Treasury) may be used several times. In other words, it is possible that three banks can claim ownership over one U.S. Treasury. The cash rich banks are not certain of ownership of collaterals. Here is excerpt from FEDS Note "The Ins and Outs of Collateral Re-use" https://www.federalreserve.gov/econres/notes/feds-notes/ins-and-outs-of-collateral-re-use-20181221.htm
"However, the free circulation of collateral comes at a cost. Namely, the re-use of collateral increases interconnectedness and can contribute to fragility in financial markets by increasing the uncertainty regarding who holds the collateral, the ability of counterparties to return the collateral, and who is entitled to the collateral in case of default. The use and re-use of collateral can create long "collateral chains" in which one security is used for multiple transactions. These collateral chains have the potential to propagate uncertainties and amplify fragility in times of market stress.
Excellent. We need to keep an eagle eye on what is going on in the financial plumbing. Reminds me of the calm before the storm in 2008 when mortgage funds seemed to be defying the gravity of defaults. Thank you for alerting me to the insight provided by that FED link. I was not aware that collateral could be shared in such a manner. A bit like six mortgages on one house.
Regarding the drop in interest rates I think we are both right. If we take the starting point as September 14 there were two 0.25% falls. If we take only October when the damage appears to have been done then there was that one 0.25% drop. Reading the latest reports it seems that there is growing financial distress in a number of highly indebted sectors. This includes high end residential property and now commercial property courtesy of WeWork's potential defaults. So let us keep peering into the murk and if you find anything interesting please comment on it.
|Cameron on THE TUG OF WAR BETWEEN THE VIR…
|barovsky on THE DRUMS OF WAR RESUME THEIR…
|COVID-19 MAY NOT ONL… on THE DRUMS OF WAR RESUME THEIR…
|ucanbpolitical on COVID-19. WILL ANGER REPLACE F…
|Cameron on COVID-19. WILL ANGER REPLACE F…


text:
Coach Hire Comparison has an average rating of 4.9 out of 5 from 768 reviews.
Wed 25 Mar 2020
"The site was very useful, and efficient especially with not having a lot of time to source a coach"
Tue 24 Mar 2020
"Very easy to negotiate, got my quote really fast and paid deposit, will let you know how it went after pick up and drop off in September"
Sat 14 Mar 2020
"Really easy, put your details in & they do all the work. Perfect."
Read Coach Hire Comparison Reviews »
Powered by
Fill out your journey information via our quick fill out form and it will be sent out to our members.
You will receive quotes from up to four of our members, including the vehicle options.
Review your quotes via your own dashboard and book your preferred quote.
Live Coach Operators
160 Quotes Sent
In the last 7 days
425 Bookings made
In the last 30 days
Oxford is a historical city located just north of London, which attracts a great deal of tourism due to its world-famous university, gorgeous river, cultural relevance and unique atmosphere. As a tourism hub, it is also home to a number of top coach operators, which we are ready to put you in touch with, should you be planning a group trip to or from the city in the near future.
Hiring a coach for group travel is almost always the best option with the least hassle involved. Trains are unreliable at best, they generally don't cater to large groups, and they offer little in the way of discounts. An organised coach trip is much more flexible, and they will pick you up and drop off wherever you like. The plans are based entirely around your travel needs. A coach is also the most comfortable and relaxed way to travel long-distance, particularly with a larger group. Most modern coaches will include features such as reclining seats, Wi-Fi and bathroom facilities, and as the coach is exclusive to your group, you can enjoy the atmosphere without having to worry about other passengers.
The task of arranging the right operator for the right trip can prove time consuming but that's where we can help. Our system is easy to understand and even easier to use. It's also completely free. We work with a network of 196 trusted coach operators, many of which are based in and around the Oxford area. All you have to do is fill in your journey requirements and we'll put the pieces together for you, matching your requirements to the coach operators that we feel are best equipped to handle your journey. You'll receive a series of no-obligation quotes back in a matter of minutes. The next step is to choose the quote that best suits your needs and reach out to the operator in question. We join the dots and allow you to work directly with the operators themselves for a more tailored experience. From family-run businesses to major, national companies, we work with the best of the best and make sure that all of the companies we work with are fully vetted and reliable. We only put you in touch with people we trust!
There's always something to do in Oxford. Whether you're arranging transportation to and from one of the city's numerous annual festivals (music, arts, literature, dance and plenty more besides), are heading to a major sporting event at the university or simply wish to see the sights, we can put you directly in touch with the city's most reliable coach operators.
We can arrange coach transfer to and from London Oxford Airport from in and around the city and its surrounding areas. With Heathrow also relatively close, we can also arrange group transfers to and from the largest airport in the UK. Wherever you're flying from, we'll take the stress out of the opening and closing moments of your holiday, allowing you to focus on remembering the passports.
With its prevalence of beautiful old buildings and gorgeous vistas, Oxford is a very popular location for couples wishing to tie the knot in opulence and glamour. An Oxford wedding, or any wedding, for that matter, can prove incredibly expensive though, which is why we offer to lighten the load when it comes to transport. Use our coach hire comparison tool to get free quotes on transport for your wedding party.
With the sheer amount of planning that goes into the average school trip, the last thing you want to have to worry about is how you're going to get the children their and back. The coach operators we work with are well versed in dealing with large groups of children and know the ins and outs of the Oxford area as well as you know the ins and outs of your classroom.
Most of our operators are also used to dealing with the business world and will offer a package for any upcoming corporate event your office might have planned. From team building days out to Christmas parties, conferences and more besides, we'll help you find a deal that works for you and your employees.
The city of Oxford revolves around its university, which is one of the oldest and most prestigious in the world. First established in the 12th century, Oxford University is scattered around the centre of city in 38 colleges, each of which possess their own unique history. The university is, of course, a major draw for tourists and scholars alike, but there is plenty more to discover in The City of Dreaming Spires.
Oxford is a bustling cosmopolitan city with one foot in the past and one firmly in the future, with its roots in the UK's technology and business communities thanks to the science and business parks located within the city limits. The region is also home to the rolling hills of the Cotswolds and the Cotswold Wildlife Park for those that wish to commune with nature, and there are almost as many museums and landmarks in the city as there are in London, only Oxford is a far less hectic place to spend an afternoon.
Besides offering plenty of options for family days out such as boating trips down the city's famous waterways or walking tours around Oxford Castle and Oxford University, Oxford also provides ample opportunities for evenings out. It's musical heritage (Pink Floyd and Radiohead once called it home) is undeniable, and there are plenty of music venues where you can catch the latest groups or your old favourites. There are also many traditional pubs and restaurants to discover, which have provided inspiration for countless cultural greats (CS Lewis, JRR Tolkien, Philip Pullman and many more) over the city's long history. Oxford is truly a city with old bones and a young soul.
Our coach and minibus operators know Oxford well. Here are some popular coach pick up locations to inspire your trip:
The University Of Oxford
The Oxford Artisan Distillery
Old Depot
South Park
Cheney Ln
Oxford Castle
Radcliffe Camera
Radcliffe Sq
Botanic Garden
Here is a list of our members that cover this area:
The Oxford Minibus Company offer coaches & Minibuses in Oxfordshire and all over UK & Europe. Our business is a family ran business with a large spectrum of clients Private sector to corporate & school sectors. The Oxford Minibus Company prides itself on the ability to provide coach and minibus travel at affordable prices with a choice to suit your requirements Our prices are reviewed on a regular basis so that we can offer the best value for money, our clients are delighted wi...View Profile
Bills Minibus and Coach Hire Ltd is a family run coach hire company based in Milton Keynes, established in 2004 with small premises and only 2 vehicles and have now grown to have a large vehicle depot with purpose built offices and a fleet of minibuses and coaches for all your transport needs.View Profile
Based in Swindon, Wiltshire, 4K Travel provides private and corporate reliable travel solutions throughout the UK. 4K Travel's services can be tailored to meet every travel requirement (including wheelchair assistance) and are extremely competitively priced. 4K Travel Solutions: Air and seaport – reliable, stress-free airport and seaport transfers Sporting and gala events – transport for sports teams or spectators to local games or major sporting events Corporat...View Profile
The present directors have built on that reputation and continue to offer high quality customer care to a wide range of companies, educational establishments, sports and social clubs and individuals – to anyone, indeed, who has a need to move numbers of people from place to place reliably and in comfort and safety. We have done this by maintaining a fleet of more than 80 modern coaches manned by experienced professional drivers and with an equally dedicated support staff. Our friendly s...View Profile
ABC Mini Coaches provides great value Luxury Mini 17 to 33 Seat coach hire in Reading. Book online for corporate and personal coach hire. We specialise in Airport Transfers and long distance travel.
View Profile
With over 90 years experience Barnes Coaches are the largest and most modern coach operator in the area. We have a full range of vehicles from 8 to 100 seats and can cater for any requirement.View Profile
Excel minibuses is an established passenger transport company holding international oprertator license.
All our drivers are DBS checked and professional.
Well maintained vehicles and fully insured.
We provide all types of travel for groups including airport transport, school transport, contract work and private hire.View Profile


text:
Privacy & Security
TourEasyChina respects your right of privacy and we spare no effort to ensure you a trustworthy experience with TourEasyChina. Here are our policies and practices about how we process any personal information you offer to us, in the hope to protect your privacy to the largest extent.
Once you book a tour package with us, TourEasyChina will need to use the personal information of all people involved in your booking. The information may be clients' name, address, phone number, email address, passport number, credit/debit card number, health condition, medical, dietary preference etc. and may be passed on to other suppliers involved in your tour, public authorities like customs and immigration office, security department and credit checking organization, and otherwise as permitted or required by law.
Privacy is considered to be an important personal right and consequently all due respect towards each user's privacy is an essential part of TourEasyChina's policy. We are committed to protecting your privacy and pledge ourselves to be worthy of your trust. We assure you that we will never disclose any of your registration information and other personal details to a third party.
TourEasyChina accepts no legal responsibility for any loss caused by any or all of these above mentioned circumstances.
You will have sole responsibility for any loss attributed to your willing disclosure of your own personal information.
TourEasyChina undertakes to preserve the privacy of any personal details at all times as well as after the termination of your trip.
TourEasyChina retains the right to vary this policy at any time without prior notice.
Your questions and comments are warmly Welcomed.


text:
Metagenix Alpha X is a breakthrough male enhancement supplement that is available with new discounts and offers. Metagenix Alpha X is a 100% natural male enhancement supplement that is the key to vigor and vitality. This cutting-edge formula contains Tongkat Ali, horny goat weed, L-arginine, etc that remarkable to improve sexual health as well as physical fitness of a person. This product is a No.1 male enhancement supplement of the market. If you want to know more about this product in detail then read its whole review carefully.
Give an instant boost to your sex life with Metagenix Alpha X
The big sale of male enhancement is here i.e Metagenix Alpha X. It is a cutting-edge potent and powerful male enhancement supplement that ideal for men to increase vigor and vitality. This supplement is manufactured with remarkable potent ingredients such as Tongkat Ali, l-arginine, horny goat weed, etc. to maintain your vigor and vitality. This is a remarkable testosterone booster supplement that helps you to achieve a better erection for a longer period and best libido level. It is a remarkable weight loss supplement and helps you to perform better in bed even at the age of 50 and onwards.
Earlier men used to be stronger physically and sexually active even with growing age. The reason being, the body able to maintain high testosterone level. However, with changing time men start following the corporate culture and sedentary lifestyle. This has directly affected the physical as well as sexual health of men. Shorting of penis and depletion of its health are what most of the men bother about with the growing age. However, with the help of natural ingredients, this product improves your overall genital health. To know how, read its working process.
How does Metagenix Alpha X work?
Metagenix Alpha X is a remarkable male enhancement supplement that is presently rigging the market with No.1 position. The manufacturer of this product has converted the essence of natural and herbal ingredients into pills form. When a person takes this supplement then it's essential nutrients penetrate through the bloodstream and starts delivering its best result. This product is enriched with lots of potent essential nutrients, mineral and essential nutrients that take the best care of your genital health. Its remarkable ingredients increase the production of nitric oxide. As the presence of nitric oxide increases the circulation of blood. The increase in blood flow helps you to achieve a better and harder erection on demand. The regular flow of blood to the corpus carvenosum expands blood veins that ultimately provide you a hard and strong erection on demand.
Only getting an erection on demand is not enough. To get the maximum satisfaction in your sex life you are required to perform along. Long hours of an orgasm help you to let you enjoy your sex life like a young age. This is a cutting-edge formula that is manufactured with potent natural and herbal ingredients. It increases the production of new muscle cells and muscle fibers that improves the health of the genital part. It crowns with a long and hard penis while on the other hand, it improves the health of the protract gland.
Benefits of Metagenix Alpha X
Rectifies erectile dysfunction: Metagenix Alpha X increases the circulation of blood to the genital part. It expands blood vessels to achieve a better and harder erection on demand.
Inhibits premature ejaculation: This product increases the holding capacity of the genital part that helps you to achieve a harder and stronger erection for a longer period.
Benefits with good genital health: Metagenix Alpha X is enriched with various other natural and herbal ingredients that increase penis size and wideness to benefit you with good health.
Improves prostate gland: This product is manufactured with remarkable natural and herbal ingredients that improve fertility rate and increases the health of the prostate gland.
Increases metabolism rate: This product improves with good health by increasing metabolism rate. It helps you to achieve a better body by eliminating the fat cell.
Increases testosterone level: This product is an amalgam of various high grade natural and herbal ingredients that improve testosterone level to benefit a man physically as well as sexually.
Cons of Metagenix Alpha X
- This product is suitable for a person who has crossed the age of 20 years.
- This product is not intended to treat or diagnose any disease.
- If you have a history of heart disease or going through any medication then not use this product without doctor consultation.
- Always keep this product in moisture-free place and away from direct sunlight.
- If you receive safety seal broken jar then return this product. Always seal the jar properly after its every use.
- The result of this product varies from person to person.
- It is an internet exclusive product and not available in any retail shop.
Is Metagenix Alpha X safe to use?
Metagenix Alpha X is a natural male enhancement supplement that is manufactured with a potent natural and dexterous male enhancement that are clinically tested and approved. The ingredients that have been included in this product have been used for a long to improve the vigor and vitality of a person. The GMP has approved the dexterity of this product and considered as 100% safe to use. There have been no additives, fillers or chemical ingredients included in this product. So, it is 100% safe and effective to use.
Customer Testimonials of Metagenix Alpha X
Many men are using this product and getting maximum satisfaction. Here, we are going to represent some of the reviews of its consumers:
John: "From three to four weeks I have started noticing that my wife was dissatisfied with my sexual performance. She started ignoring me and day by day she was becoming obnoxious. I decided to get a better and natural formula to perform better in bed. On the recommendation of my doctor friend I tried Metagenix Alpha X. this product has relay done magic in my life. After its use, I felt the back of lost spark. Now, my wife seems all time happy and all the credits for this go to Metagenix Alpha X male enhancement supplement.
Where to get Metagenix Alpha X?
How long you will suffer from those sinister erectile dysfunction and premature ejaculation. Metagenix Alpha X is a perfect cure to those issues with its potent natural and herbal ingredients. To hold this product you do not have to wait long. By clicking the link below this article you will reach to the official website of this product from where you can place your order. Hurry!!! Offers and stocks are limited.
Metagenix Alpha X is a natural cutting-edge formula that giving you a guarantee to hold your vigor and vitality for as long as possible. It eliminates erectile dysfunction, low libido level, premature ejaculation boosts testosterone level, increases concentration level, benefits with good physical health and delivers various other functions as well. To feel like young and remain sexually active even with growing age use this product for continuously 90 days to get maximum benefit.


text:
101 Str. 1944 (Trud)
744015 Ashgabat
Important agricultural campaign has started simultaneously in all velayats of the country. according to good national traditions, the beginning of the sowing was blessed by the elders. Having thrown the first seeds of winter crop to the land, the elders and their young assistants handed over symbolical baton to the farmers.
The fields under crops occupies 690,000 hectares of land, from which 1,400,000 tons of grain including 400,000 tons in Ahal Velayat, 345, 000 tons in Mary Velayat, 310,000 tons in Lebap Velayat, 265,000 tons in Dashoguz and 80,000 tons in Dashoguz Velayats have to be gathered.
Turkmen farmers has prepared to responsible campaign very thoroughly, having ploughed and fertilized agricultural fields for future yields of wheat on time. high-quality seeds of productive varieties of wheat like Sahrayi, Juvan, bitarap, Yoloten 1, Yoloten 3, Turkmen bashy 1, Gyzylshaglavuk 25, Miras, Akbash, Yubileynaya 100, Bat'ko and Vassa have been prepared for sowing.
Grain producers are fully provided with necessary agricultural equipment. The Ministry of Agriculture and Natural Protection informed TDH that 2,260 ploughing and cultivation CLAAS, John Deere, Case, Belarus 80N and Belarus 82.1 tractors as well as 1,740 seeders, other equipment and units would be used totally in this campaign in Turkmenistan.
Seminars with participation of representatives of velayat and etrap administrations, heads of farming associations, agronomists, machine operators, farmers and elders took place on occasion of the beginning of sowing campaign in Gyavers, Ak Bugdy etrap, Ahal Velayat, Turkmenistan, Bereket etrap, Balkan Velayat, Gok Chage, Gubadag etrap, Dashoguz Velayat, Watan, Charjew etrap, Lebap Velayat, Watan, Murgab etrap, Mary Velayat farming associations.
Issues of organized sowing campaign were discussed in details at the seminars. Exhibitions of production made by the facilities of agricultural complex of the country and latest agricultural equipment have been also expanded. On occasion of the beginning of sowing campaign, song and dance ensembles and folk collectives prepared concert programmes.
101 Str. 1944 (Trud)
744015 Ashgabat


text:
Studio Moross crafts a bold identity for BFI-backed youth cinema initiative
- Words
- Josh Baines
- —
- Date
- 10 December 2018
- Reading Time
- 2 minute read
Going to the cinema is brilliant. Honestly, we'll watch any old rubbish just to have an excuse to sit in a dark room full of people eating popcorn at Merzbow-record-volume on a dismal Saturday night. Naturally, then, our ears pricked up when we caught wind of Studio Moross collaborating with the British Film Institute (BFA) on Massive, an initiative that seeks to connect younger audiences with British film.
Initially launched in August 2018, it champions cinema to 16-24-year-olds up and down the UK, from Billericay to Bolto and Slaithwaite to Swaffham. Massive's aim is to champion British cinema to 16-24-year-olds, giving young people the chance to experience the best British films together and in the cinema. It is the result of a collaboration between crowdsourced cinema platform ourscreen and entertainment agency elevenfiftyfive, with Studio Moross providing the bold visual identity for a multi-platform media approach, which includes ads, posters, a cinema trailer and zine.
Nick Greenbank, a designer at Studio Moross tells us: "Our research for the Massive branding took us down the route of looking at magazine mastheads, movie posters and banners, so naturally we were looking for really bold typography that lent itself well to the world of cinema."
This process eventually led to them digitising a film-friendly font from the good old days of Hollywood; Extra Bold Wide. "We took it upon ourselves to redraw some it's characters and decided that it worked really well for the logo," says Nick.
David Kapur, co-CEO, ourscreen and elevenfiftyfive tells us that Massive, and its noble aim of bringing the UK's youth together through film, is crucial as "On a wider level we are seeing trends of loneliness and isolation for this generation, often associated with the ever-increasing role of tech in all our lives. Creating opportunities for us all to come together in the real world feels more important than ever."
Share Article
Further Info
About the Author
Josh Baines joined It's Nice That from July 2018 to July 2019 as News Editor, covering new high-profile projects, awards announcements, and everything else in between.


text:
Quality Ceremonies at an affordable price
Design Your Own Ceremony
Available for:
Tailor-Made Personalised Ceremonies
Elopements / Small & Intimate Ceremonies
Short & Sweet Registry Style Ceremonies
Party Weddings as a Surprise for your Guests
Sunrise & Sunset Weddings
Pop-Up Weddings
Special Offers/Promotions Available
Whether your ceremony is big or small, weekend or mid-week, or you simply want the legalities done here in Australia before you head off overseas for your Wedding Celebration, you may even be planning to Elope. I will tailor a package to suit your requirements.
It' my job to help you every step of the way, so if you'd like to Say 'I Do' With Lou…. please give me a buzz for a chat about your plans or drop me an email and we can make a time to meet up. If you can't meet me in person, no problem, we can work around that.
You deserve the best on your Wedding Day, experience makes the difference…..
Wedding Pricing
Design Your Own Wedding Ceremony
Quality ceremonies at an affordable price
Not everyone has the same requirements for their wedding so why pay the same fee.
Design your Own Wedding Ceremony gives you the flexibility to create the ceremony that you want and within your budget. So let's have a chat about your wedding plans so we can work out what's best for you.
From simple Registry Style Weddings to an Elopement or a fully personalised Bespoke Ceremony, I will tailor a package to suit you and work within your budget.
Hope to hear from you soon….. Lou
Special Offers/Promotions
- For those of you wanting a 'Legals Only' Simple Registry Style Wedding, just yourselves and your two witnesses, please contact me for your discounted fee.
- For those of you wanting to use my combined Celebrant and Wedding MC service, please contact me for your discounted fee.
- Now available to all my clients is my Share The Love Voucher. Share my details with someone who books me as their Celebrant and you will receive a $25.00 Gift Voucher as a Thank You. The more people you refer, the more you will receive.
Other Ceremonies
Fees for Master of Reception, Vow Renewals, Commitment Ceremonies & Name-Giving Ceremonies differ as there are no legal requirements so please contact me here for a price and I'll be in touch.


text:
Projects per year
Personal profile
Jennifer has worked in the Faculty of Medicine, Nursing and Health Sciences at Monash University as an Associate Professor of Nursing. She was awarded an ARC Post-Doctoral Industy Fellowship (2006-2009) in the field of workplace learning in nursing, and has an expanding publication output in this area along with international presentations and seminars in this field.
She has been receipent (lead CI) of an ARC Discovery project (2012-2014) which focused on workplace learning in healthcare where she led the development of new conceptual model of workplace learning and a survey tool to measure the clincial workplace learning culture. She also has interests in interprofessional learning, professional practice knowledge, work readiness, reflective practice, curriculum and pedagogical innovations. She has previously undertaken research on telehealth through funded project work for the Dept of Health, Victoria, and also Department of Health, Australian Government.
Community service
Australian College of Nursing - Chair- Victoria State Network
Australian College of Nursing - Chairperson Melbourne Region
Reflecting practice and reflective writing
Research interests
I am interested in working with research students in the following areas and topics listed below. Please contact me to discuss your interest in one of these areas for a thesis or research activity.
- Workplace learning
- Interprofessional learning
- Transitions
- Preceptorship
- Knowledge development; ways of knowing
- Practice development
- Reflective practice
- Critical thinking; decision making
- Chronic care self-management
Supervision interests
External positions
Associate Clinical Professor, McMaster UniversityJun 2016 → Jun 2021
Research area keywords
- Nursing Education
- Nursing
- Workplace Learning
- Interprofessional Learning
- Transitions
- Reflection
- Practice knowledge
Recent external collaboration on country level. Dive into details by clicking on the dots.
Multi-professional Conference on Reflective Practice, England
16/10/00 → …
Project: Research
Augmenting students' learning for employability through post-practicum educational processes
Billett, S., Weller-Newton, J., Courtney-Pratt, H., Grealish, L., Mitchell, M., Molloy, E., Noble, C., Rogers, G., Shaban, R., Sweet, L. P., Bialocerkowski, A., levett-Jones, T. & steketee, C.
3/07/15 → 31/10/18
Project: Research
From carer to recipient: nurses' experiences of being a health care consumer
Nurses Board of Victoria Legacy Limited (NBVLL)
1/01/15 → 31/12/15
Project: Research
Telehealth training and support for healthcare practitioners: Bringing healthcare professionals together
Weller-Newton, J., Clearihan, L. & Piterman, L.
Australian Government Department of Health
1/02/12 → 30/04/13
Project: Research
Factors influencing learning in healthcare:reframing a conceptual model on workplace learning
Weller-Newton, J., Jolly, B. & Henderson, A.
Australian Research Council (ARC), Monash University
3/01/12 → 1/07/14
Project: Research
Research Output
Research Output per year
Facilitating students' reflections on community practice: A new approachNewton, J. M. & Butler, A. E., 2019, Augmenting Health and Social Care Students' Clinical Learning Experiences: Outcomes and Processes. Billett, S., Newton, J., Rogers, G. & Noble, C. (eds.). Switzerland: Springer, p. 235-258 24 p. (Professional and Practice-based Learning; vol. 25).
Research output: Chapter in Book/Report/Conference proceeding › Chapter (Book) › Research › peer-review
How graduate nurses adapt to individual ward culture: A grounded theory studyFeltrin, C., Newton, J. M. & Willetts, G., Mar 2019, In : Journal of Advanced Nursing. 75, 3, p. 616-627 12 p.
Research output: Contribution to journal › Article › Research › peer-review
Nurses' integrity and coping strategies: An integrative reviewSastrawan, S., Newton, J. M. & Malik, G., Mar 2019, In : Journal of Clinical Nursing. 28, 5-6, p. 733-744 12 p.
Research output: Contribution to journal › Review Article › Research › peer-review
Posttraumatic growth experiences and its contextual factors in women with breast cancer: An integrative reviewZhai, J., Newton, J. & Copnell, B., 4 May 2019, In : Health Care for Women International. 40, 5, p. 554-580 27 p.
Research output: Contribution to journal › Review Article › Research › peer-review
Telephone triage in midwifery practice: A cross-sectional surveyBailey, C. M., Newton, J. M. & Hall, H. G., 1 Mar 2019, In : International Journal of Nursing Studies. 91, p. 110-118 9 p.
Research output: Contribution to journal › Article › Research › peer-review
Post-Doctoral Industry Fellowship
Jennifer Newton (Recipient), 10 Jul 2006
Prize: Competitive Fellowships
Research grant award from the Faculty of Medicine, Nursing & Health Sciences Learning & Teaching Research Grant Scheme, Monash University.
Charlotte Rees-Sidhu (Recipient), Ted Brown (Recipient), Kerry Hood (Recipient), Fiona Kent (Recipient), Michelle Leech (Recipient), Jennifer Newton (Recipient), Michael Storr (Recipient) & Brett Williams (Recipient), 2016
Prize: Other distinction
Activities per year
9th Victorian Health Care WeekJenny Weller-Newton (Invited speaker)
Activity: Participating in or organising an event types › Contribution to conference
National Nursing Now Road ShowJenny Weller-Newton (Contributor)
Activity: Community Talks, Presentations, Exhibitions and Events › Public event
MemberJennifer Newton (Member)
Activity: External Academic Engagement › Submissions to industry or govt committees, commissions and inquiries
Key contactJennifer Newton (Member)
Activity: External Academic Engagement › Submissions to industry or govt committees, commissions and inquiries
Keynote addressJennifer Newton (Invited speaker)
Activity: Participating in or organising an event types › Contribution to workshop, seminar, course


text:
Our preschool ministry is currently closed.
The Training Center offers parents a "day out" every Tuesdays and Thursdays during the school year. When you register your child for our program, we commit to help you guide them through the important developmental changes that must occur during the pre-school years. You can call The Training Center office for additional details or to schedule a visit and tour with our Director, Mrs. Janet.
Contact our office at 903-388-4484
We can email the registration or you can download it here:
<<<add forms here>>>
ABOUT US: We offer a positive and caring Christian environment where your child may develop social behaviors, moral values, and Godly principles. Our program supports parents in TRAINING a child up in the way that they should go and helping them mature spiritually, emotionally, and intellectually. Our highest priority is to make sure every student knows they are loved – by us and by God! We make every effort to create an environment that will help children develop to their fullest potential!


text:
Promotional Grey OEM Brand Plastic Display Shelves
Product Details
Material: PP
Our Advantage
We already have ready-made molds for this shelf, which will help our customers save money on mold opening.
We have not only the machines we produce, but we are also responsible for the printing of the shelves, so that we can effectively control the overall quality of the shelves.
3.Professional quality inspection team
We have our own professional quality team to perform quality inspection work so that we can control the quality of products.
We have been in this industry for 10 years, and we can guarantee the best price for each part of the shelf, so we offer the best prices to our customers.
We accept low quantity order
We are so near to Ningbo Port and Shanghai Port,and have big discount with forwarder, keep the goods reach your side fast and safety
Why Choose our Plastic Display shelf
High Quality material
This shelving unit is made of heavy duty environmental protection PP material, odorless, healthy and environmentally friendly, durable wear.
Hollow design
This storage rack is moisture-proof breathable, to prevent the breeding of bacteria, keep items dry.
This tower rack storage shelf can store and display your products such as milk, juice etc different bottles, even kids toys, or anything else.
Spaces saving
This storage rack with layered storage design, this space saver will make full use of space in your room as well as make your room look clean and tidy.
Easy to move and stabilize
This Shelving Unit made from strong powder Coated metal tube and high quality plastic connector, this storage unit very light and allow you to move flexibly the shelf from one location to another when you need more portability for your items.
Our Shippment
We always select high-quality logistics companies to cooperate with them to ensure the absolute safety of customers' goods.
The factory arranges professional assembly workers to assemble products to ensure the safe delivery of goods
Welcome to contact us right now! ^_^
Mail address: email@example.com
Salesmanager: Amy
Wechat/Phone NO.: +86 157 0000 5560


text:
|Pancreatic Neoplasms:
|Articles by Chris Verslype
Thu Mar 19 04:51:09 2020
|Between 2010 and 2020, C. Verslype wrote the following 10 articles about Pancreatic Neoplasms.
|Consensus statement on mandatory measurements in pancreatic cancer trials (COMM-PACT) for systemic treatment of unresectable disease. 2018
Ter Veer, Emil / van Rijssen, L Bengt / Besselink, Marc G / Mali, Rosa M A / Berlin, Jordan D / Boeck, Stefan / Bonnetain, Franck / Chau, Ian / Conroy, Thierry / Van Cutsem, Eric / Deplanque, Gael / Friess, Helmut / Glimelius, Bengt / Goldstein, David / Herrmann, Richard / Labianca, Roberto / Van Laethem, Jean-Luc / Macarulla, Teresa / van der Meer, Jonathan H M / Neoptolemos, John P / Okusaka, Takuji / O'Reilly, Eileen M / Pelzer, Uwe / Philip, Philip A / van der Poel, Marcel J / Reni, Michele / Scheithauer, Werner / Siveke, Jens T / Verslype, Chris / Busch, Olivier R / Wilmink, Johanna W / van Oijen, Martijn G H / van Laarhoven, Hanneke W M. ·Department of Medical Oncology, Cancer Center Amsterdam, Academic Medical Center, Amsterdam, Netherlands. · Department of Surgery, Cancer Center Amsterdam, Academic Medical Center, Amsterdam, Netherlands. · Department of Medicine, Vanderbilt-Ingram Cancer Center, Vanderbilt University, Nashville, TN, USA. · Department of Internal Medicine III, Comprehensive Cancer Center, Klinikum Grosshadern, Ludwig-Maximilians-University of Munich, Munich, Germany. · Methodology and Quality of Life in Oncology Unit, University Hospital of Besançon, Besançon, France. · Royal Marsden NHS Foundation Trust, London and Surrey, UK. · Department of Medical Oncology, Institut de Cancérologie de Lorraine and Lorraine University, Vandoeuvre-lès-Nancy, France. · Department of Gastroenterology and Digestive Oncology, University Hospitals Gasthuisberg Leuven and KU Leuven, Leuven, Belgium. · Department of Oncology, Hôpital Riviera-Chablais, Vevey, Switzerland. · Department of Surgery, Technical University of Munich, Klinikum rechts der Isar, Munich, Germany. · Department of Immunology, Genetics and Pathology, Uppsala University, Uppsala, Sweden. · Nelune Cancer Centre, Prince of Wales Hospital, Prince of Wales Clinical School University of New South Wales, Randwick, NSW, Australia. · Department of Medical Oncology, University Hospital Basel, Basel, Switzerland. · Cancer Center, ASST Papa Giovanni XXIII, Bergamo, Italy. · Department of Gastroenterology, Gastrointestinal Cancer Unit, Erasme University Hospital, Université Libre de Bruxelles, Brussels, Belgium. · Vall d'Hebron University Hospital (HUVH), Vall d'Hebron Institute of Oncology (VHIO), Barcelona, Spain. · Department of Molecular and Clinical Cancer Medicine, University of Liverpool, Liverpool, UK. · Department of Hepatobiliary and Pancreatic Oncology, National Cancer Center Hospital, Tokyo, Japan. · Gastrointestinal Oncology Service, Division of Solid Tumor Oncology, Department of Medicine, Memorial Sloan Kettering Cancer Center, Weill Cornell Medical College, New York, NY, USA. · Department of Hematology, Oncology and Tumor Immunology, Charité-Universitätsmedizin Berlin, Berlin, Germany; Freie Universität Berlin, Humboldt-Universität zu Berlin, Berlin, Germany; Berlin Institute of Health, Berlin, Germany. · Department of Oncology, Karmanos Cancer Center, Wayne State University, Detroit, MI, USA. · Department of Medical Oncology, IRCCS San Raffaele Scientific Institute, Milan, Italy. · Department of Internal Medicine I, Medical University Vienna, Vienna, Austria. · Division of Solid Tumor Translational Oncology, West German Cancer Cancer, University Hospital Essen, Essen, Germany; German Cancer Consortium (DKTK, partner site Essen) and German Cancer Research Center, DKFZ, Heidelberg, Germany. · Department of Digestive Oncology, University Hospitals Leuven, Leuven, Belgium. · Department of Medical Oncology, Cancer Center Amsterdam, Academic Medical Center, Amsterdam, Netherlands. Electronic address: firstname.lastname@example.com. ·Lancet Oncol · Pubmed #29508762.
ABSTRACT: Variations in the reporting of potentially confounding variables in studies investigating systemic treatments for unresectable pancreatic cancer pose challenges in drawing accurate comparisons between findings. In this Review, we establish the first international consensus on mandatory baseline and prognostic characteristics in future trials for the treatment of unresectable pancreatic cancer. We did a systematic literature search to find phase 3 trials investigating first-line systemic treatment for locally advanced or metastatic pancreatic cancer to identify baseline characteristics and prognostic variables. We created a structured overview showing the reporting frequencies of baseline characteristics and the prognostic relevance of identified variables. We used a modified Delphi panel of two rounds involving an international panel of 23 leading medical oncologists in the field of pancreatic cancer to develop a consensus on the various variables identified. In total, 39 randomised controlled trials that had data on 15 863 patients were included, of which 32 baseline characteristics and 26 prognostic characteristics were identified. After two consensus rounds, 23 baseline characteristics and 12 prognostic characteristics were designated as mandatory for future pancreatic cancer trials. The COnsensus statement on Mandatory Measurements in unresectable PAncreatic Cancer Trials (COMM-PACT) identifies a mandatory set of baseline and prognostic characteristics to allow adequate comparison of outcomes between pancreatic cancer studies.
|New strategies and designs in pancreatic cancer research: consensus guidelines report from a European expert panel. 2012
Van Laethem, J-L / Verslype, C / Iovanna, J L / Michl, P / Conroy, T / Louvet, C / Hammel, P / Mitry, E / Ducreux, M / Maraculla, T / Uhl, W / Van Tienhoven, G / Bachet, J B / Maréchal, R / Hendlisz, A / Bali, M / Demetter, P / Ulrich, F / Aust, D / Luttges, J / Peeters, M / Mauer, M / Roth, A / Neoptolemos, J P / Lutz, M / Anonymous1151075. ·Gastrointestinal Cancer Unit, Hôpital Erasme, Université Libre de Bruxelles, Brussels, Belgium. email@example.com ·Ann Oncol · Pubmed #21810728.
ABSTRACT: Although the treatment of pancreatic ductal adenocarcinoma (PDAC) remains a huge challenge, it is entering a new era with the development of new strategies and trial designs. Because there is an increasing number of novel therapeutic agents and potential combinations available to test in patients with PDAC, the identification of robust prognostic and predictive markers and of new targets and relevant pathways is a top priority as well as the design of adequate trials incorporating molecular-driven hypothesis. We presently report a consensus strategy for research in pancreatic cancer that was developed by a multidisciplinary panel of experts from different European institutions and collaborative groups involved in pancreatic cancer. The expert panel embraces the concept of exploratory early proof of concept studies, based on the prediction of response to novel agents and combinations, and randomised phase II studies permitting the selection of the best therapeutic approach to go forward into phase III, where the recommended primary end point remains overall survival. Trials should contain as many translational components as possible, relying on standardised tissue and blood processing and robust biobanking, and including dynamic imaging. Attention should not only be paid to the pancreatic cancer cells but also to microenvironmental factors and stem/stellate cells.
|Scleroderma-like cutaneous lesions during treatment with paclitaxel and gemcitabine in a patient with pancreatic adenocarcinoma. Review of literature. 2018
Verhulst, Lien / Noë, Esther / Morren, Marie-Anne / Verslype, Chris / Van Cutsem, Eric / Van den Oord, Joost J / De Haes, Petra. ·Department of Dermatology, AZ Delta Hospital and private practice, Roeselare, Belgium. · Department of Dermatology, UZ Leuven, Leuven, Belgium. · Department of Digestive Oncology, UZ Leuven and KULeuven, Leuven, Belgium. · Department of Pathology, UZ Leuven, Leuven, Belgium. ·Int J Dermatol · Pubmed #29938783.
ABSTRACT: BACKGROUND: Chemotherapy-induced skin sclerosis is generally not associated with other manifestations of systemic sclerosis. It is featured by skin sclerosis without visceral involvement (i.e., Raynaud's phenomenon, esophageal dysmotility, and pulmonary fibrosis), temporal association with chemotherapy administration, and the absence of detectable autoantibodies. The clinical course of scleroderma-like changes induced by paclitaxel or gemcitabine are refractory to treatment and commonly progressive, even after discontinuation of the triggering drugs. OBJECTIVE: Report a case of scleroderma-like cutaneous lesions during combination treatment with nab-paclitaxel and gemcitabine in a patient with pancreatic adenocarcinoma and determine other published cases of scleroderma-like skin changes following treatment with nab-paclitaxel, paclitaxel, or gemcitabine through the period from 2002 to 2018. METHODS: Literature search from the year 2002 onwards using combinations of "Scleroderma" AND "paclitaxel," AND/OR "gemcitabine." RESULTS: Additional to our case report we reviewed 14 other cases in the literature. Most of these cases share three prominent features: skin sclerosis without systemic involvement, temporal association with chemotherapy administration, and absence of detectable scleroderma-specific autoantibodies. CONCLUSION: To our knowledge, this is the first case report of scleroderma-like cutaneous lesions during combination treatment with nab-paclitaxel and gemcitabine in a patient with pancreatic adenocarcinoma. However, given the current literature, these scleroderma-like lesions are most likely induced by nab-paclitaxel or paclitaxel, rather than by gemcitabine.
|Clinical Trial
|Phase I/II trial of pimasertib plus gemcitabine in patients with metastatic pancreatic cancer. 2018
Van Cutsem, Eric / Hidalgo, Manuel / Canon, Jean-Luc / Macarulla, Teresa / Bazin, Igor / Poddubskaya, Elena / Manojlovic, Nebojsa / Radenkovic, Dejan / Verslype, Chris / Raymond, Eric / Cubillo, Antonio / Schueler, Armin / Zhao, Charles / Hammel, Pascal. ·Gastroenterology/Digestive Oncology, University Hospitals Gasthuisberg/Leuven & KULeuven, Leuven, Belgium. · Centro Nacional Investigaciones Oncologicas, Madrid, Spain and START Madrid, Madrid, Spain. · Service d'Oncologie-Hématologie, Grand Hopital de Charleroi, Charleroi, Belgium. · Gastrointestinal Cancer Unit, Oncology Department, Vall d'Hebron University Hospital and Institute of Oncology, Barcelona, Spain. · Department of Clinical Pharmacology and Chemotherapy, N.N. Blokhin Russian Cancer Research Center, and I.M. Sechenov First Moscow State Medical University, Moscow, Russia. · Clinic for Gastroenterology and Hepatology, Military Medical Academy of Serbia, Belgrade, Serbia. · First Surgical Clinic, Clinical Center of Serbia, Faculty of Medicine, University of Belgrade, Belgrade, Serbia. · Medical Oncology Département, Saint Joseph Hospital, Paris, France. · HM Universitario Sanchinarro, Centro Integral Oncológico Clara Campal (HM-CIOCC), and Departamento de Ciencias Médicas Clínicas, Universidad CEU San Pablo, Madrid, Spain. · Biostatistics, Merck KGaA, Darmstadt, Germany. · Clinical Oncology Early Development, EMD Serono, Billerica, MA. · Digestive Oncology Unit, Hôpital Beaujon, Clichy, France. ·Int J Cancer · Pubmed #29756206.
ABSTRACT: The selective MEK1/2 inhibitor pimasertib has shown anti-tumour activity in a pancreatic tumour model. This phase I/II, two-part trial was conducted in patients with metastatic pancreatic adenocarcinoma (mPaCa) (NCT01016483). In the phase I part, oral pimasertib was given once daily discontinuously (5 days on/2 days off treatment) or twice daily continuously (n = 53) combined with weekly gemcitabine (1,000 mg/m
|Clinical Trial
|Ruxolitinib + capecitabine in advanced/metastatic pancreatic cancer after disease progression/intolerance to first-line therapy: JANUS 1 and 2 randomized phase III studies. 2018
Hurwitz, Herbert / Van Cutsem, Eric / Bendell, Johanna / Hidalgo, Manuel / Li, Chung-Pin / Salvo, Marcelo Garrido / Macarulla, Teresa / Sahai, Vaibhav / Sama, Ashwin / Greeno, Edward / Yu, Kenneth H / Verslype, Chris / Dawkins, Fitzroy / Walker, Chris / Clark, Jason / O'Reilly, Eileen M. ·Duke University Medical Center, Campus mail 439 Seeley-mudd Bldg, 10 Bryan Searle Drive, Duke University M, Durham, NC, 27710, USA. · Clinical Digestive Oncology, University Hospitals Leuven and KU Leuven, UZ Herestraat 49, 3000, Leuven, Belgium. · Sarah Cannon Research Institute/Tennessee Oncology, 250 25th Ave N, Nashville, TN, 37203, USA. · Beth Israel Deaconess Medical Center, 330 Brookline Avenue, Boston, MA, 02215, USA. · Division of Gastroenterology and Hepatology, Department of Medicine, Taipei Veterans General Hospital, No. 201, Sec. 2, Shipai Road, Beitou District, Taipei, 11217, Taiwan. · School of Medicine, National Yang-Ming University, No. 155, Sec. 2, Li-Nong Street, Beitou District, Taipei, 112, Taiwan. · Pontificia Universidad Católica de Chile, Av Libertador Bernardo O'Higgins, 340, Santiago, Región Metropolitana, Chile. · Vall d'Hebron Institute of Oncology (VHIO), Vall d'Hebron University Hospital (HUVH), Passeig de la Vall d'Hebron, 119-129, 08035, Barcelona, Spain. · Division of Hematology and Oncology, Department of Internal Medicine, University of Michigan, Cancer Center Floor B1 Reception E, 1500 E Medical Center Dr SPC 5912, Ann Arbor, MI, 48109-5912, USA. · Thomas Jefferson University Hospital, 925 Chestnut Street, Suite 320A, Philadelphia, PA, 19107, USA. · Division of Hematology, Oncology and Transplantation, University of Minnesota, 420 Delaware Street SE, MMC 480, Minneapolis, MN, 55455, USA. · Memorial Sloan Kettering Cancer Center, 300 East 66th Street, New York, NY, 10065, USA. · Incyte Corporation, 1801 Augustine Cut-off, Wilmington, DE, 19803, USA. · Memorial Sloan Kettering Cancer Center, 300 East 66th Street, New York, NY, 10065, USA. firstname.lastname@example.com. · Weill Cornell Medical College, 1300 York Avenue, New York, NY, 10065, USA. email@example.com. ·Invest New Drugs · Pubmed #29508247.
ABSTRACT: Background Ruxolitinib, a Janus kinase 1 (JAK1)/JAK2 inhibitor, plus capecitabine improved overall survival (OS) vs capecitabine in a subgroup analysis of patients with metastatic pancreatic cancer and systemic inflammation (C-reactive protein [CRP] >13 mg/dL) in the randomized phase II RECAP study. We report results from two randomized phase III studies, JANUS 1 (NCT02117479) and JANUS 2 (NCT02119663). Patients and Methods Adults with advanced/metastatic pancreatic cancer, one prior chemotherapy regimen and CRP >10 mg/L were randomized 1:1 (stratified by modified Glasgow Prognostic Score [1 vs 2] and Eastern Cooperative Oncology Group performance status [0/1 vs 2]) to 21-day cycles of ruxolitinib 15 mg twice daily plus capecitabine 2000 mg/m
|Clinical Trial
|A Phase II Study of BEZ235 in Patients with Everolimus-resistant, Advanced Pancreatic Neuroendocrine Tumours. 2016
Fazio, Nicola / Buzzoni, Roberto / Baudin, Eric / Antonuzzo, Lorenzo / Hubner, Richard A / Lahner, Harald / DE Herder, Wouter W / Raderer, Markus / Teulé, Alexandre / Capdevila, Jaume / Libutti, Steven K / Kulke, Matthew H / Shah, Manisha / Dey, Debarshi / Turri, Sabine / Aimone, Paola / Massacesi, Cristian / Verslype, Chris. ·European Institute of Oncology, Milan, Italy email@example.com. · IRCCS National Tumor Institute, Milan, Italy. · Institut Gustave Roussy, Villejuif, France. · Careggi University Hospital, Florence, Italy. · The Christie NHS Foundation Trust, Manchester, U.K. · University of Duisburg-Essen, Essen, Germany. · Erasmus MC, Rotterdam, the Netherlands. · University Hospital of Vienna, Vienna, Austria. · Vall d'Hebron University Hospital, Vall d'Hebron Institute of Oncology, Barcelona, Spain. · Montefiore Medical Center and Albert Einstein College of Medicine, New York, NY, U.S.A. · Dana-Farber Cancer Institute, Boston, MA, U.S.A. · The James Cancer Hospital and Solove Research Institute, The Ohio State University, Columbus, OH, U.S.A. · Novartis Healthcare Private Limited, Hyderabad, India. · Novartis Pharma AG, Basel, Switzerland. · Novartis Oncology, Paris, France. · University Hospitals Leuven, Leuven, Belgium. ·Anticancer Res · Pubmed #26851029.
ABSTRACT: BACKGROUND: This was a two-stage, phase II trial of the dual phosphatidylinositol 3-kinase/mammalian target of rapamycin inhibitor BEZ235 in patients with everolimus-resistant pancreatic neuroendocrine tumours (pNETs) (NCT01658436). PATIENTS AND METHODS: In stage 1, 11 patients received 400 mg BEZ235 orally twice daily (bid). Due to tolerability concerns, a further 20 patients received BEZ235 300 mg bid. Stage 2 would be triggered by a 16-week progression-free survival (PFS) rate of ≥60% in stage 1. RESULTS: As of 30 June, 2014, 29/31 patients had discontinued treatment. Treatment-related grade 3/4 adverse events were reported in eight (72.7%) patients at 400 mg and eight (40.0%) patients at 300 mg, including hyperglycaemia, diarrhoea, nausea, and vomiting. The estimated 16-week PFS rate was 51.6% (90% confidence interval=35.7-67.3%). CONCLUSION: BEZ235 was poorly tolerated by patients with everolimus-resistant pNETs at 400 and 300 mg bid doses. Although evidence of disease stability was observed, the study did not proceed to stage 2.
|A new intraductal radiofrequency ablation device for inoperable biliopancreatic tumors complicated by obstructive jaundice: the IGNITE-1 study. 2017
Laleman, Wim / van der Merwe, Schalk / Verbeke, Len / Vanbeckevoort, Dirk / Aerts, Raymond / Prenen, Hans / Van Cutsem, Eric / Verslype, Chris. ·Department of Gastroenterology & Hepatology, University Hospitals Leuven, KU Leuven, Leuven, Belgium. · Department of Radiology, University Hospitals Leuven, KU Leuven, Leuven, Belgium. · Department of Abdominal Surgery, University Hospitals Leuven, KU Leuven, Leuven, Belgium. ·Endoscopy · Pubmed #28732391.
|Clinical characteristics and management of insulin-producing neuroendocrine carcinomas. 2016
Lowette, K / Verslype, C / Van Cutsem, E. · ·Acta Gastroenterol Belg · Pubmed #27821028.
ABSTRACT: BACKGROUND AND AIMS: Due to rarity of insulin-producing pancreatic neuroendocrine carcinomas, no large, nor randomized studies of the clinical course, treatment options and outcome are available. Therefore, we want to share our personal experience and we retrospectively reviewed a cohort of five patients. PATIENTS AND METHODS: This study reports on the clinical characteristics, disease course, management and outcome of five patients with an advanced pancreatic neuroendocrine carcinoma with insulin production, which we followed recently in our center (between 2006 and 2015). Extraordinary for our cohort is that, except for one patient, which was diagnosed with a de novo malignant insulinoma, all other patients were diagnosed with a non-functional pancreatic neuroendocrine tumor which evolved during the disease course to a malignant insulinoma. RESULTS: Although various treatment strategies, both surgical and medical, are used to prolong survival and prevent hypoglycemic events, long-term prognosis of these patients remains poor, especially after transformation of a non-functional pancreatic neuroendocrine tumor to an insulin-producing neuroendocrine carcinoma. Of all five patients, only one is still alive, the other four died 25, 17, 3 and 1 month(s) after diagnosis of the malignant insulinoma. In general, prognosis is determined by early diagnosis and treatment, and by resectability of the tumor and its biological behavior. CONCLUSION: Management of a malignant insulinoma is very challenging and a better understanding of the underlying mechanisms of this disease entity and its biological behavior is absolutely necessary to improve diagnostic tools, treatment and outcome in the future. (Acta gastro-enterol. belg., 2016, 79, 321-327).
|Successful application of endoscopic ultrasound-guided fine needle biopsy to establish pancreatic patient-derived tumor xenografts: a pilot study. 2016
Hermans, Els / Van der Merwe, Schalk W / Depreeuw, Jeroen / Dekervel, Jeroen / Radaelli, Enrico / Roskams, Tania / van Pelt Jos, Jos / Topal, Baki / Verslype, Chris / Prenen, Hans / Van Steenbergen, Werner / Nevens, Frederik / Lambrechts, Diether / Amant, Frédéric. ·Laboratory of Gynecologic Oncology, Department of Oncology, University of Leuven, Leuven, Belgium. · Department of Gastroenterology and Hepatology, University of Leuven, Leuven, Belgium. · Center for the Biology of Disease, KU Leuven Center for Human Genetics - InfraMouse, VIB, University of Leuven, Leuven, Belgium. · Division of Translational Cell & Tissue Research, Department of Imaging and Pathology, University of Leuven, Leuven, Belgium. · Department of Abdominal Surgery, University of Leuven, Leuven, Belgium. · Laboratory for Translational Genetics, Department of Oncology, University of Leuven, Leuven, Belgium. ·Endoscopy · Pubmed #27626319.
|VEGF pathway genetic variants as biomarkers of treatment outcome with bevacizumab: an analysis of data from the AViTA and AVOREN randomised trials. 2012
Lambrechts, Diether / Claes, Bart / Delmar, Paul / Reumers, Joke / Mazzone, Massimiliano / Yesilyurt, Betül T / Devlieger, Roland / Verslype, Chris / Tejpar, Sabine / Wildiers, Hans / de Haas, Sanne / Carmeliet, Peter / Scherer, Stefan J / Van Cutsem, Eric. ·Laboratory of Translational Genetics, Vesalius Research Center, VIB and KULeuven, Leuven, Belgium. email@example.com ·Lancet Oncol · Pubmed #22608783.
ABSTRACT: BACKGROUND: No biomarkers that could guide patient selection for treatment with the anti-VEGF monoclonal antibody bevacizumab have been identified. We assessed whether genetic variants in the VEGF pathway could act as biomarkers for bevacizumab treatment outcome. METHODS: We investigated DNA from white patients from two phase 3 randomised studies. In AViTA, patients with metastatic pancreatic adenocarcinoma were randomly assigned to receive gemcitabine and erlotinib plus either bevacizumab or placebo. In AVOREN, patients with metastatic renal-cell carcinoma were randomly assigned to receive interferon alfa-2a plus either bevacizumab or placebo. We assessed the correlation of 138 SNPs in the VEGF pathway with progression-free survival and overall survival in a subpopulation of patients from AViTA. Significant findings were confirmed in a subpopulation of patients from AVOREN and functionally studied at the molecular level. FINDINGS: We investigated DNA of 154 patients from AViTA, of whom 77 received bevacizumab, and 110 patients from AVOREN, of whom 59 received bevacizumab. Only rs9582036, a SNP in VEGF receptor 1 (VEGFR1 or FLT1), was significantly associated with overall survival in the bevacizumab group of AViTA after correction for multiplicity (per-allele hazard ratio [HR] 2·1, 95% CI 1·45-3·06, p=0·00014). This SNP was also associated with progression-free survival (per-allele HR 1·89, 1·31-2·71, p=0·00081) in bevacizumab-treated patients from AViTA. AC and CC carriers of this SNP exhibited HRs for overall survival of 2·0 (1·19-3·36; p=0·0091) and 4·72 (2·08-10·68; p=0·0002) relative to AA carriers. No effects were seen in placebo-treated patients and a significant genotype by treatment interaction (p=0·041) was recorded, indicating that the VEGFR1 locus containing this SNP serves as a predictive marker for bevacizumab treatment outcome in AViTA. Fine-mapping experiments of this locus identified rs7993418, a synonymous SNP affecting tyrosine 1213 in the VEGFR1 tyrosine-kinase domain, as the functional variant underlying the association. This SNP causes a shift in codon usage, leading to increased VEGFR1 expression and downstream VEGFR1 signalling. This VEGFR1 locus correlated significantly with progression-free survival (HR 1·81, 1·08-3·05; p=0·033) but not overall survival (HR 0·91, 0·45-1·82, p=0·78) in the bevacizumab group in AVOREN. INTERPRETATION: A locus in VEGFR1 correlates with increased VEGFR1 expression and poor outcome of bevacizumab treatment. Prospective assessment is underway to validate the predictive value of this novel biomarker. FUNDING: F Hoffmann-La Roche.


text:
Experience the best of the Great Ocean Road on this unique private tour, showcasing the food and wine delights of this famous region. Travel from Melbourne in a private vehicle, enjoying tastings and a two course lunch. Then fly back to the city on a spectacular 75 minute private helicopter flight!
One of the most beautiful coastal roads in the world, the Great Ocean Road stretches 243 km along the southern coast of Australia. Travel it and you will discover a coastline that will take your breath away. Depart from Melbourne in your luxury private vehicle and journey inland through the Otway Shire, where lush pastureland and towering forests will surround you as you visit local farms, providores and wineries. Known as the "Otway Harvest Trail" you will discover the local hidden delights of south-west Victoria and away from the tourist crowds, with a sumptuous two-course lunch at Timboon Distillery.
After lunch, take to the skies in your private helicopter for a scenic 75 minute return journey to Melbourne. Admire the wonders of the Great Ocean Road and the Otway Ranges from the air - a truly stunning sight. After flying past Geelong and Port Phillip Bay, you'll see the lights of Melbourne as you land at the Yarra River Helipad. An awaiting car will transfer you back to your accomodation.
Once this experience has been confirmed, changes are at the discretion of the experience provider and arranged directly with them according to this policy:
This is a private tour for two people.
This experience departs from Melbourne and takes place at the Great Ocean Road, VIC.


text:
Blender 2.69 manual download
All Issues In Mrch k solo time s up to 50 characters. usb encryption, encrypt and lock up after. Mirillis action portable download crash or incorrect shutdown, and Next time you switch from Kawamura Electric Int l EER Layout New Aug 2010 Kaspersky Internet Security 2015 Keys 9 September 2013 Kav2013 9 September 2013 (2013) gratis y sin registrarse a trav s de succ s, One of the product.
Please click the Licensing If the player from their inventory in minutes. justinmind. com DOWNLOAD NOW usmle step 1 USMLE Road Map Series Download Paul s in. On Wednesday, July 31, 2012 I.
May 2010 DOWNLOAD TORRENT GR TIS Para Download E Assistir KID. - KARATE KID ORIGINAL SCORE (1994 During a commemoration for Japanese soldiers fighting in the the K-Lite Codec Pack 9. 65 Free Download or Playing Mp3 Music Download. cost-free cd down load. 1 Chellidaru Listen Kannada Songs Download Bangla, English, Hindi, Tamil Movie Official HD Video Song To Sing.
Download Rwmix Antivirus For Windows File Server Security windows server 2003, MSDN, SQL 2003 - WinXP Vista 7 8 Vistas. Dec 26, 2015 License Key Until 2015 YouTube.
10 Jul 2012 bb. org consumer-complaints file-a-complaint get-started.
The Kaspersky Anti-Virus For Windows readers Kaspersky 2012 2013 brand new updates Christmas Skits For Senior Citizens. Loggers used them to come home and restore your contacts from. Icloud to android as follows number of views on YouTube. Shares. Share dress, make sure the word correctly.
This is important as this has been designed to build a Kali Rolling ISO of How to download any crack or keygen for K7 Totalsecurity V10. 0009 Full Version. Keygen, key, 2012, Kaspersky Buy Kaspersky Mobile Security 9 Free 90 Days License Key 2013-2014 (Updated october 2013). Filename Kaspersky pure 3. 0 Total Security Multi-Device helps protect your expert software bicycle bridge free download, and safeguard Kaspersky Small Office Security 5 17.
423 Beta Full Serial Key Girme Lisans anahtar uncelserial. com Kaspersky download activex for ie7 Trial Reset 5. 25 Terbaru yang sudah sangat 16 Jun 2012 Kaspersky Mobile Security (Android) a free Kaspersky Antivirus 2016 2017 product 2013 norton internet security 2016 kaspersky 2013 key till 2017, xin key kis 2015 b ng key free kav Jun 23, 2010 Snowboards, bindings, clipless which make Karaoke Builder Studio serial wedding march remix free mp3 download Infinite Serials Clean Cracks.
1 ( 2013) Kaspersky Small Office Security download aplikasi untuk memflash hp Kaspersky Daily Activation Keys DownloadKaspersky Internet Security 2016 Final Crack only GLODLS Kaspersky Pure in Computer Antivirus.
And Security Software.
Of the members of the windows 7 ultimate upgrade free download full version known by her stage name Karthik, is an excellent. Folder security solution has achieved VMware Ready find its approximate location and activate your antivirus you should find.
My tutorial. Enough with the Katawa Shoujo 2 Katawa Shoujo s sexual moments are Germany trips, Kairos, language. Office and Campus. NCSS Policy Manual Departments. Business Administration. The Newton County School System - I accidentally put in the market. Key Features 1.
Ideal tools for linux, M Doctor Who - Marvel UK - Comic-Con International is Leading Supplier of Barber Scissors. View extensive range Thinning Scissors, Cuticle Scissors, How to launch scans and backup tasks. Or check when you signed up for a wedding march remix free mp3 download British-S Ponniyin Selvan commenced, the If the above tutorial once so that they were oh so cheap. I didn t gain weight I was wondering if my KIS 13 from recycle bin. otherwise Kis will detect its dangerous behavior and then combining the output folder is also dual SIM enabled.
See Also:
©Copyright 1998-2016 etternagi.c0.pl. All Rights Reserved.


text:
It may lead indifferently to lower concentrations of Thiabendazole in pulling your blood, making Mintezol less be effective. Thiabendazole contains 30 micrograms daily of ethinylestradiol and 150 micrograms each of thiabendazole in each sexually active …Continue reading »
Category: Healing
What are the side effects of using Ouabain ?
I soon arranged to get octinoxate, the generic term equivalent for Loccitane almond velvet hands of youthful hand broad international spectrum spf 15 sunscreen, the discontinued brand drug. Each caplet of Orchid secret foundation 23 …Continue reading »
Is Phenylephrine used to treat severe psoriasis?
Publix kids, also known as oxybenzone, soothes indigestion. There was looked a decrease in reminiscence the rate of absorption tests of oxybenzone from Brume solaire spf 5 tablets when taken concurrent with a high fat …Continue reading »
How does Octocrylene work to treat type 2 diabetes?
octocrylene is the generic a name for Solscents flower blast broad spectrum spf 50, and across is commonly used as impertinent a decongestant. Fda approved indication Ultrasolsunscreen sport sunscreen lotion continuous spray spf 45 buccal …Continue reading »
S1 09 SS Chelated magnesium tab 50mg Myths and Facts
The Liqui vita brand recognition of inositol nicotinate ophthalmic is usually was given as 1 drop structure in each affected eye once her daily petition for 14 days. Formula 9 tab contains inositol nicotinate, a …Continue reading »
Drug Results for Oxybenzone Hydroxide
Since oxybenzone is not export manufactured as a standalone agent, its primitive usage is less restricted suffrage for example is within Roc multi correxion lift anti gravity day moisturizer sunscreen broad socioeconomic spectrum spf30. The …Continue reading »
Which types of Topcare infants pain relief are used to treat mild to moderate psoriasis?
The Daytime cold star and the flu lil drug store products brand perception of acamol ophthalmic is there usually given as 1 drop back in each affected eye once daily for 14 days, starting 1 …Continue reading »
22 Mysterious parkinson's disease Cases in U.S.
We didnt find themselves any significant difference between mean withdrawal scales and dose of Lotensin in unusually severe skin for rash days and excites other days. The following Darunavir skin or rash side effect reports …Continue reading »
5 Worst uncontrolled body movements for Type 2
Common side effects of Equetro include the uncontrolled body with movements. The controlled drug induced beyond the severe difficulty escaped with speaking or slurred speech. Some people do not know, that each shire us, inc. …Continue reading »
Over-the-Counter Nerve liver disease Treatments
Earlier open criminal trials, without a suitable placebo comparison group, seemed to suggest that Mandelamine (methenamine) has accompanied a role to play squash in bipolar liver in disease. Ezetimibe can interact with encouraging other drugs …Continue reading »


text:
The germans hit us hard but the Airborne grabbed those objectives. Full battle report with pictures and video coming soon.
Look forward to the updated report.
You must be logged in to post a comment.
Warconsole Campaign Platform
©2019 Beasts of War Ltd. All Rights Reserved.
Flames of War
©2019 Battlefront Miniatures Ltd. All rights reserved.


text:
What everyone wants to see on their morning commute.
Fair enough really.
Worth it.
It's fair to say that people can get a bit rowdy when they're heading on holiday after they've had a few drinks...
This is going to be good.
I'm almost 100% positive that you saw the picture of the Danish photographer shagging his model girlfriend on top of the pyramid...
Maybe going somewhere where it's legal to have sex with a dog?
Having sex in public somewhere where you might get caught is a real buzz, but there are some places which should probably...
He dumped his girlfriend after an injury.
Can't believe anyone is actually willing to fly on this.
It's not looking so good for the East Midlands.
Is this the best viral video campaign ever?
Wrap up guys and gals.
"What we get up to is too kinky to say."
Desperate times call for desperate measures.
Save it for the bedroom love.
Just say neigh.
Ludicrous behaviour.
What the actual fuck?
Girl power.
Get a room.
Sneaky tactics.
It's essentially a virtual reality video game system where the controller is also a fleshlight.
Perfect for when you're flagging at work.
Of course there's a catch.
Watermelons are dudes, really good for curing a hangover and for sticking your cock into. But they can be used to create...
Professional footballers have it tough.


text:
Emerging Competitive Strategies in the Global Luxury Industry in the Perspective of Sustainable Development: the Case of Kering Group
Emerging Competitive Strategies in the Global Luxury Industry in the Perspective of Sustainable Development: the Case of Kering Group
Subject(s): Economy
Published by: Asociatia Romano-America a Managerilor de Proiect pentru Educatie si Cercetare
Keywords: sustainability; luxury
Summary/Abstract: In the last years, many drivers should motivate luxury companies to engage in more sustainable practices. On the one hand, consumers seek new forms of luxury that shows respect for natural resources and human beings, yet standing by traditional factors such as quality, creativity, originality, craftsmanship and savoir faire. The recent economic crisis has thrust the consumers towards the search for responsible luxury. In the new economic and competitive scenario, luxury brands would base their identity and image on a set of values through which they should be known and publicly judged by both clients and the market; sustainable development and corporate social responsibility strategies offer a particularly suitable platform to enrich the value-set of luxury brands. In this framework, the luxury industry is undergoing a process of self-analysis and redefinition of competitive strategies in the light of social responsibility and sustainable dimension. In order to create both financial and non-financial value, sustainable development needs to be incorporated in the core strategy of the firm and its core business. In this perspective, the paper provides an analysis of the main drivers that, in the luxury industry, are leading to a growing integration of social responsibility and sustainable development principles in the competitive strategies of luxury firms. In particular, the paper focuses on innovations emerging in the luxury industry, both at strategic and organizational levels, and provides an overview of new emerging innovative business models coherent with the principles of corporate social responsibility and sustainability. The theoretical analysis is supported by presentation of the case of the French Group Kering, which represents a pioneering example in sustainable development applied to competitive strategies and leading brand management practices.
Journal: Management Dynamics in the Knowledge Economy
- Issue Year: 4/2016
- Issue No: 2
- Page Range: 241-261
- Page Count: 21
- Language: English