text:
Brenner Children's pediatric emergency department has moved back to its original location. Learn more
In order to help protect patients, family members and health care workers from the spread of COVID-19, no visitors are allowed at any of Wake Forest Baptist Health's outpatient or inpatient facilities, except in certain situations.Learn moreMore COVID-19 Updates
Most nosebleeds look worse than they are. In other words, nosebleeds are messy, a little uncomfortable, and sometimes even scary, but they're usually no big deal.
A kid might get nosebleeds just once in a while or more often. The nosebleeds that are most common in kids usually happen near the front of the nose, on the wall separating the two sides of the nose (the septum), and usually start from just one nostril.
Sometimes nosebleeds start further back in the nose, but this is rare and mostly happens in older people or those who have high blood pressure or injuries to their nose or face.
Most nosebleeds happen when the little blood vessels that line the inside of the nose break and bleed. These blood vessels are very fragile and lie very close to the surface, which makes them easy targets for injury.
Common reasons are:
Less often, injuries to the outside of the nose, face, or head can cause nosebleeds. If this happens, you need to see a doctor right away. You can help prevent these types of nosebleeds by wearing protective gear, such as helmets for hockey, football, and baseball and any other sport or activity that requires them.
Some nosebleeds may be caused by a problem with the blood's clotting system, but this is rare.
You know that you should see a doctor if your nosebleed was caused by an injury, such as a punch. But what if it just starts bleeding on its own?
Follow these steps:
Here are some other cases when you need to see the doctor or visit the emergency department:
If you'd like to get fewer nosebleeds, what can you do? Well, don't pick your nose or stick anything up your nose. Also, avoid blowing your nose too forcefully, and if you have allergies, see a doctor about them. If you get your allergies under control, your nose probably won't be as stuffy and irritated.
When the inside of your nose feels dry and itchy, it can be tempting to pick it, so talk to your mom or dad about trying one or two of these tips to keep it moist:
Reviewed by: Anoop K. Palta, MD
Date reviewed: January 2015
© 2019 Brenner | Site Policies & Statements
The information on this Website is for general informational purposes only and SHOULD NOT be relied upon as a substitute for sound professional medical advice, evaluation or care from your physician or other qualified healthcare provider. If you have a medical problem or a health-related question, consult your physician or call Health On-Call at 336-716-2255 or 1-800-446-2255.

subset: commoncrawl


text:
Genworth Financial (GNW) announced Thursday that it is selling its Genworth Financial Wealth Management unit to a partnership of two private equity firms—Genstar Capital and Aquiline Capital—for $412.5 million.
According to the parent company, the deal is expected to close in the second half of 2013, and it will take a $40 million after-tax loss, with $35 million recorded in the first quarter. Genworth Financial said proceeds of the deal would be used to "address" its debt coming due in 2014 or before.
What will the deal mean for advisors who use Genworth Financial Wealth Management's platform? According to Gurinder Ahluwalia (left), president and CEO, there will be no short-term changes for those RIAs and independent BD reps who form the core of GFWM's advisor clients.
Longer term, he said, the acquisition will be positive for advisors, leading to "more enhancements and more investment in the business," which includes its TAMP investment platform and technology and practice management tools, including Altegris' liquid alternative investing products.
"Genworth decided we weren't core to their business," Ahluwalia said in a Thursday interview, while with its new owners, "we have a couple of firms who love our business." Not only will Ahluwalia and his management team stay in place, so will GFWM's "mission and organization," he said. "You want to be in a place where your vision is shared by your corporate parents," Ahluwalia said, and as for his management team, "We're pretty jazzed."
When asked whether the two private equity firms were interested in a shorter-term return on their investment, Ahluwalia said that while he couldn't speak for Genstar and Aquiline, he knew that a short turnaround of their investment was not the plan. "We're going to invest in the business for a longer-term outcome. For me that means new solutions—investing or technology," he said, mentioning that he and his top managers were engaged in the presale discussions: "We've engaged with them our vision of a multiyear plan; they're absolutely aligned with our growth objectives."
Those words were echoed in Genstar and Aquiline's announcement of the acquisition, stating that "Aquiline and Genstar will bring their operational expertise and industry experience to help GFWM and Altegris increase their scale and capabilities," specifically "to enhance product development and technology offerings at GFWM, and expand distribution channels and launch new alternative products at Altegris."
Jeff Greenberg, CEO of New York-based Aquiline, called GFWM and Altegris "market-leading businesses with strong brands, experienced management teams and high growth potential," while San Francisco-based Genstar principal Tony Salewski said in the same statement that GFWM and Altegris were "each well-positioned to meet the growing needs of independent financial advisors and increased demand from retail investors for access to alternative products."
Ahluwalia has guided GFWM from its beginnings as Genworth Financial Asset Management to an integration with AssetMark Investment Services and then acquisitions of Quantuvis Consulting and Altegris, making GWFM one of the fastest-growing investment outsource providers to advisors. While the name of the company will change—"that's something we'll be working on from now until closing" of the deal—he argues that what won't change is the firm's focus on risk management. "It's such an important principle for advisors," he said, "around their practice but also for their investment clients."
Read LTCI Benefits Exceed $6B in 2012 on AdvisorOne.


text:
Pivotal has released Version 1.0 of its Spring IO Java framework. Its project team claims to have reported popularity among the Cloud Foundry developer community and the commercial PaaS (Platform-as-a-Service) developer community.
Attempting to encapsulate the world of big data in an Agile kind of way, Spring IO is modular and brings together the core Spring APIs into a "versioned foundation" for Java developers.
Spring IO supports enterprise Java workloads across mobile, web apps, integration, web services, batch, relational, no SQL, reactive and big data applications, as well as APIs and micro services.
Version 1.0 creates an easier way for developers to consume Spring in projects where multiple Spring IO components are used. It does this by eliminating compatibility issues within Spring's project ecosystem and third-party libraries.
"To ensure high software quality and a great developer experience, we've run extensive tests to harmonize 36 Spring projects, and 436 third-party dependencies on both Java 7 and 8, to ensure software quality and portability," said Hugh Williams, senior vice president of research and development, Pivotal.
"Now application teams have the development flexibility of using a modular, portable application framework requiring only Java SE, at a greatly reduced expense in testing, and with the ability to upgrade at predictable six month intervals."
Spring IO runs on Java 7 or 8, on either standalone Java Virtual Machines (JVMs), on servlet engines such as Apache Tomcat, Jetty and Pivotal tc Server, and on full-blown Java EE 1.6 + application servers.
Spring IO 1.0 includes all major Spring Projects, with the exception of Spring XD, which is expected to be generally available later this year.


text: Friday, September 14, 2012 CMS Revamps Medicaid RAC Website The Centers for Medicare and Medicaid Services (CMS) recently revamped its Medicaid Recovery Audit Contractor (RAC) website to promote transparency and incorporate feedback from states and industry stakeholders. The enhanced RACs At A Glance website includes state-reported information on each state's RAC program, the name of each RAC vendor and medical director, contact information for the state program integrity director, and user-friendly charts and data. CMS's role in the Medicaid RAC program focuses on providing guidance to states as they implement their Medicaid RAC programs, monitoring the progress of those programs, and encouraging states to make their Medicaid RAC programs as transparent as possible.


text:
Welcome to THE PETULANT POETESS, a moderated online fiction archive dedicated to both Harry Potter Fanfiction and Original Stories and Poetry.
The Petulant Poetess archive was founded by NotSoSaintly in April of 2005 with the idea of creating a friendly atmosphere, dedicated to guiding and encouraging budding authors as well as accommodating the more seasoned writer. Stories going through the moderation process receive a final polishing through communication with the author with the express intent of presenting quality stories for the reader. A list of hard-working admins who contribute their free time out of love for the craft of writing and helping others may be found on the About Us page.
So grab a story off the shelf, pull up a chair, and get comfortable; the library is open, the tea (or coffee if you prefer) is hot, and everyone is welcome.
Please note that access to adult-rated stories requires a membership, which is restricted to people over the age of majority. View our Terms of Use and Compliance Statement for more information. Our Submission Rules are readily available to all writers who wish to post with us.


text:
TD Ameritrade Holdings (AMTD) announced Tuesday net income of $675 million, or $1.22 per diluted share, on record net revenues of $2.76 billion for its fiscal year ended Sept. 30, 2013. In its fiscal fourth quarter, TD Ameritrade had net income of $200 million, or $0.36 per diluted share, on revenues of $709 million. Both earnings numbers beat analysts' consensus estimates slightly.
In an interview with ThinkAdvisor, CEO Fred Tomczyk said "we're very happy" with the results, noting that it was the fifth straight year that the company had achieved double-digit net new client asset growth; this year posting 10% growth in net client assets of about $50 billion. He also expressed satisfaction that "expenses haven't grown in three years," and that at TD Ameritrade Institutional, "we continue to increase the size of our clients." He said that the "combination of $50 billion in net new assets and strong expense controls" proves that "our management team has done a good job."
Additionally, Tomczyk noted that the company increased its annual dividend 33% and instituted a special $0.50 dividend. "We've returned over 100% of our earnings to shareholders," he declared.
While TD does not break out separate results for its retail and advisor units, in his discussion with analysts about the earnings report this morning, Tomczyk pointed out that TDAI had added 389 breakaway brokers to its RIA custody business, which "enjoyed strong growth driven by new and existing RIAs." He further said that its pipeline of prospective new advisor clients was "robust."
Speaking of the overall market and economy and a recent downturn in consumer confidence, Tomczyk said that "gridlock in Washington is affecting consumers' psychology," but if "we just got rid of the uncertainty in Washington" the government could increase its revenue by "geting the economy going." However, he said that "this kind of market plays into the hands of RIAs."
Addressing regulatory issues facing RIAs, Tomczyk reiterated TD Ameritrade's concern that when it comes to any fiduciary standard imposed by the SEC, "we don't want it watered down."
Check out ThinkAdvisor's 2013 Q3 Earnings Calendar for the Finance Sector.


text:
It's been seven years since ring-tailed master thief Sly Cooper has headlined a video game - about three times the lifespan of a typical wild raccoon. The guy's been on Sony's bench since his creators, Sucker Punch Productions, moved on to the "InFamous" series, so you could forgive him if his skills are rusty.
Fortunately, a second studio called Sanzaru Games has rescued the rascally raccoon from a life of knocking over garbage cans. "Sly Cooper: Thieves in Time" (Sony, for the PlayStation 3, $39.99; Vita, $29.99) finds him chilling out in Paris, until he discovers that pages are disappearing from his prized family history, the "Thievius Raccoonus."
The Paris prologue, a strictly linear sequence that feels like too many other generic platform games that have been released during Sly's hiatus, gets "Thieves in Time" off to a sluggish start. But once Sly and his pals - Bentley, the techie turtle, and Murray, the two-fisted hippo - start traveling back through time, the action gets much livelier.
Each stop in the time machine introduces a series of challenges that borrow elements from, seemingly, the entire history of video games. There are shooting galleries, stealth sequences, mine-cart races, rhythm games - and, of course, the core of the funny-animal genre: running, jumping and climbing across 3D worlds.
That's a lot to cram into one game, and some missions work better than others. I found Murray's slugfests tedious - he moves like, well, a hippo - but enjoyed the two-dimensional shoot-'em-ups that Bentley uses to hack into enemy computers.
But "Thieves in Time" soars when it allows the nimble Sly to do what he does best: skittering up drainpipes, scampering across power lines, bouncing across rooftops. To get the most out of the game, you should take breaks from its main story missions to search for the treasures scattered throughout its well-designed, semi-open worlds.
The journey takes the gang to the Wild West, feudal Japan and beyond, all the way back to the Ice Age. Sly's ancestors, like gunslinger Tennessee Cooper, ninja Rioichi Cooper and the prehistoric "Bob" Cooper, are charming, though a few of the villains veer dangerously close to offensive ethnic stereotypes.
"Thieves in Time" doesn't break new ground, but it does serve as a lively affectionate tribute to a genre that once dominated the video-game world. I hope it isn't the last we've seen of Sly. Two and a half stars out of four.
Follow Lou Kesten on Twitter at https://twitter.com/lkesten


text:
Final debate: Murphy, McMahon wrangle over Social Security
Hartford — U.S. Senate candidates Chris Murphy and Linda McMahon thrust and parried Thursday over the familiar subjects of jobs plans and Social Security in their fourth and final debate, yet also touched on the women's vote, their opponent's best qualities and how a Norwegian submarine ended up in a campaign ad referencing Electric Boat.
The late-afternoon debate followed the morning release of a University of Connecticut/Hartford Courant poll that shows Democratic Murphy with a 44 percent to 38 percent lead on Republican McMahon among likely voters, with 17 percent still undecided.
But McMahon maintains an 8-point lead in eastern Connecticut's 2nd Congressional District.
Among women voters statewide, Murphy outpolls McMahon 50 percent to 32 percent. And McMahon leads among men, 45 percent to 37 percent.
The poll of 574 likely voters was conducted from Oct. 11 to Oct. 16 and reports a margin of error of plus or minus 4 percentage points.
The one-hour debate, hosted by the Connecticut Broadcasters Association, was broadcast live from a chandeliered ballroom in the Hartford Hilton Hotel. It featured a more subdued audience than attended Monday's debate at the Garde Arts Center in New London. That evening was notable for the rowdy and disobedient crowd that clapped, catcalled and sometimes drowned out the candidates.
Both candidates stuck to their usual overarching themes Thursday.
McMahon presented herself as a proven job creator with a six-point plan for reviving the economy and lowering unemployment. She portrayed Murphy as a "career politician" who is clueless about the private sector.
Murphy, the current 5th Congressional District representative, described himself as a fighter for the middle class who wants to raise taxes on society's wealthiest to finance education and infrastructure investments and pay down some of the national debt. He painted McMahon as a closet right-winger who would empower a Tea Party-led majority in the Senate.
The candidates gave very different answers to the question of how they define the middle class.
For the purpose of her jobs plan, the middle class is the "spread" beneath the top end of her proposed 15 percent income tax rate (a decrease from the current 25 percent), McMahon said. That rate would top out at $86,000 a year for a single person and $143,000 for a married couple.
"My plan is not about a tax cut for me. My plan is about a tax cut for the middle class," said McMahon, a Greenwich multimillionaire.
Murphy replied that for him, "being part of the middle class is a mentality."
"I think a family that's struggling to make their budget work, who would be in dire straights if they missed a couple paychecks, that's the middle class," said Murphy, who has come under fire in the race for having once skipped rent, mortgage and car payments.
McMahon was asked to specify how she would accomplish her goal of working in a bipartisan manner to keep the Social Security program solvent. The WWE entrepreneur vowed not to support any budget that reduces benefits for current beneficiaries, but she declined to give specifics on what exactly she has in mind for reforms. She said she doesn't mention such details while out campaigning "because they get demagogued."
Murphy offered a cynical retort, arguing that her secret intent is to end Social Security as a program: "She says she's going to get demagogued, that may be another way of saying she's going to lose votes."
Asked for reform specifics of his own, Murphy called for raising the cap that exempts income above $110,000 from Social Security taxes.
"Social Security has 20 years before it starts taking in less money than it sends out, so if you adjust the cap today, you can solve the Social Security issue 20 years from now," he said.
McMahon responded to a question on the veracity of campaign ads by pointing out a current Murphy ad which touts his support for submarine production at EB but uses stock video footage of a foreign-made diesel sub flying a Norwegian flag.
"Those kind of ads just need to be corrected," said McMahon, who is presently airing a rival ad mocking the flag gaffe. "To the people in Groton, I think it was very hurtful."
Murphy's campaign staff have admitted to accidentally using stock footage of a foreign sub.
"I think the fact that Linda McMahon's campaign is reduced to arguing over B-roll footage in our campaign ads shows you how little she wants to talk about the issues," Murphy responded.
There was also disagreement over whether McMahon is truly pro-choice.
"Linda McMahon is not pro-choice," Murphy asserted, noting comments on the Facebook page of a prominent social conservative, Peter Wolfgang, who is voting for McMahon "because her victory could mean the end of Roe v. Wade."
McMahon said Murphy was wrong.
"I will not support my party in repealing any of these laws because I am a pro-choice candidate," she said, adding, "I am an independent thinker, and I will not vote strictly along party lines."
The candidates were later asked to say something nice about the other. Murphy praised McMahon's ambition and her charitable donations. McMahon mentioned the congressman's two sons, ages 4 and 11 months, saying, "They are so cute."
Stories that may interest you
UPDATED: Local police leaders say Minneapolis incident erodes trust of community; demonstrators 'stand witness'
Police chiefs in Groton, New London and Norwich spoke out about the George Floyd incident as members of the community planned a small "Black Lives Matter" public witness gathering Friday afternoon in New London.
Preston residents offer mixed opinions on proposed school budget
A debate over the proposed $12.2 million school budget dominated a two-hour budget teleconference public hearing Thursday night.
Region's summer camps canceled or modified due to pandemic
With new state safety regulations and the ongoing COVID-19 crisis, private and town-run programs are either shutting down or adapting.
After 'some progress,' Lamont signs off on casino reopenings
Foxwoods Resort Casino and Mohegan Sun, set to open to the public Monday for the first time in 11 weeks, will cater to invited guests during "soft" openings over the weekend.


text:
Learn about the market conditions for Okeechobee County. Use the filters to find more specific details about what you want to learn. This data is direct from the multiple listing service (MLS), which is the most reliable real estate database of home sales.
Our expert agents will provide you one at no cost.
Colored buttons are On.
White buttons are Off.
There is no description for this area...
We promise not to sell or share your contact information, but we may need to ask you questions before we can finalize the value for your house.
Whether you're looking to buy or sell, allow our expert agents to help guide you through the process.
We promise not to sell or share your contact information with anyone else.


text:
Model #KTX-4848
|List Price:
|Our Price:
General Description
We're committed to exceeding your expectations:
- Found it for less? We'll match the price
- 25-Year or Limited Lifetime Warranty
Our customers come first — we guarantee it!
Take your cafeteria tables to a whole new level of style with these counter-height cafe tables. Perfect for both school cafeterias and office dining areas, these tables are as practical as they are attractive. The high-pressure laminate surface is spill and stain-resistant and a breeze to clean even with just a damp cloth.
The iron X-base adds stability as well as leg room, allowing patrons to sit in comfort and enjoy their lunch. Available in a beautiful choice of rich colors, these cafeteria tables will make any dining experience more enjoyable.
- Manufacturer:
KFI Seating gives new meaning to the standard concept of stacking chairs. Their full line of completely stackable chairs can be adapted for any application you wish.
- Width:
- 48 in.
- Length:
- 48 in.
- Height:
- 29 in.
- Weight:
- 105 lbs.
- Folding:
- No
- Frame Finish:
Powder Coated
Powder coat is a paint finish that is electro-statically applied to steel components leaving a highly-durable, scratch-resistant, rust-free, eco-friendly finish.
- Frame Specs:
16-gauge, 3" Dia
Gauge is a measurement of steel thickness - the lower the gauge, the thicker the steel.
- Meets ANSI-BIFMA:
- Yes
- Seating Capacity:
- 4
- Style:
- Cafe and Pedestal Tables
- Tabletop Core Material:
Particleboard is made from wood particles and resin. It is cost-effective and versatile.
- Tabletop Edge:
- Vinyl T-mold
- Tabletop Support:
- Steel, Cast Iron Base
- Tabletop Surface Material:
High-Pressure Laminate
High-pressure laminate is the finish commonly found on kitchen counters (commonly known as Formica). It is extremely durable and easy to clean.
- Tabletop
- 1.25"
- Warranty:
- Limited Lifetime
- Made in USA
- Classic Style: Classic cafe-type tables add pizzazz to school and office dining areas.
- Easy Maintenance: 1-1/4" High-pressure laminate tabletops are easy to clean, facilitating cleanup between meals.
- Extra-Comfortable: X-base provides ample leg room for better comfort.
- No-Peel Edging: T-mold edge banding is super-durable and won't peel.
- Rich Colors: Choice of rich colors allows these tables to be matched to any decor.
- Lifetime Coverage: Our Limited Lifetime Warranty guarantees many years of use and enjoyment.
High-Pressure Laminate is an extremely durable and easy-to-clean surface, commonly used on kitchen counters, office desks and tables.
Powder coat paint is a quality paint finish made by electro-statically applying powder paint to steel and then baking it in an oven. This results in a super-smooth and durable finish.
This product is made with pride in the United States of America!
We're committed to exceeding your expectations:
- Found it for less? We'll match the price
- 15-Year or Limited Lifetime Warranty
Our customers come first — we guarantee it!
Shipping & Assembly
- Ships Via:
- Common Carrier
- Leaves Factory In:
- Approximately 2-3 weeks
- Assembly:
- Minimal
- Average Assembly Time:
- 10 Minutes
Deluxe Square Cafe Table with X-Base
|List Price:
|Our Price:
Product Family
This product is a part of Cafeteria Tables with X-Bases
There are 24 products in the family


text:
Sunday News Round-Up, Level 90 Edition
- First up, a reminder that the Educate Congress campaign keeps rolling – we just hit 100 supporters of the effort to send a copy of the current Our Bodies, Ourselves book to all members of the U.S. Congress! We're about 20% of the way to our goal now, so still need your support!
- Hurricane preparedness tips from the CDC for my east coast friends.
- At Vanderbilt University, a campus map of places where breastfeeding is welcome. Now, because of state law, women are actually allowed to breastfeed anywhere women are allowed to be. So I don't really like the "breastfeeding welcomed here" language of the campaign *because regardless of personal feelings of welcome, it's allowed everywhere.* It probably is nice to know which places aren't likely to result in hassle, though, and some of these places have spaces set up where women can do so privately if desired. It's nice that any effort is being made to be more supportive, though, and I hope that managers of the many, many women who aren't in office jobs at a university are being supported in taking the break time necessary to make use of these spaces.
- See also this post on the Take Back the Night event happening at Vanderbilt this Tuesday night.
- Relatedly, in the New York Times this week: Student's Account Has Rape in Spotlight, on how campus leadership can fail victims of assault:
"Eventually I reached a dangerously low point, and, in my despondency, began going to the campus' sexual assault counselor," the woman wrote in The Amherst Student. "In short I was told: No you can't change dorms, there are too many students right now. Pressing charges would be useless, he's about to graduate, there's not much we can do. Are you SURE it was rape?"
- Yecch, Roseanne Barr – that was some unpleasant, cissexist business (explanation via Marti at The Transadvocate).
- Jacqueline at Laika's MedLibLog makes the important point that being published in a high-profile journal *is not* in itself evidence that the study findings are true or reliable, in Why Publishing in the NEJM is not the Best Guarantee that Something is True: a Response to Katan.
- For my public health geeks, there's a new MMWR app for the iPad.
- At Feministe, Donate for an Actual Cure – a response to October pinkwashing.
- In "Why I am Pro-Life" at the New York Times, Thomas L. Friedman writes (emphasis added):
In my world, you don't get to call yourself "pro-life" and be against common-sense gun control — like banning public access to the kind of semiautomatic assault rifle, designed for warfare, that was used recently in a Colorado theater. You don't get to call yourself "pro-life" and want to shut down the Environmental Protection Agency, which ensures clean air and clean water, prevents childhood asthma, preserves biodiversity and combats climate change that could disrupt every life on the planet. You don't get to call yourself "pro-life" and oppose programs like Head Start that provide basic education, health and nutrition for the most disadvantaged children. You can call yourself a "pro-conception-to-birth, indifferent-to-life conservative." I will never refer to someone who pickets Planned Parenthood but lobbies against common-sense gun laws as "pro-life."
- Ruth White at Provoking Policy talks about the ethics of studying people in poverty, in Good intentions, exploitation and studying 'the poor.':
I think it is time to leave poor people alone; to use our power to protect them from our insatiable curiousity about their lives through actively fighting with them for social policies that raise their standard of living and education and gives them more access to resources and power. Replicability may be a founding principle of science but after a point we move to redundancy. If we still feel the need to ask questions of the poor, perhaps we can let them guide the way. This means we give up our 'intellectual superiority' and become servants to the poor, asking the questions to which they want answers. This may mean less articles for me to review for lofty (and not so lofty) journals but it may mean that more of what we write gets read by more people, and more of what we read educates us in a meaningful way that makes social change possible.
- Via Melissa McEwan at Shakesville, Mourdock Ain't Sorry, You Losers! – because honestly, the idea that your deity is hands-on enough to give you a rape baby but not enough to bother preventing your rape makes your deity seem kind of egregious.
- There's no clip I can find to embed, but on this week's Real Time with Bill Maher, panelist Chrystia Freeland made the point nobody ever wants to make, but which I believe – rape exceptions for abortion are hypocritical from a purely pro-life standpoint. Freeland explained that if your objection to abortion is that life is sacred and once an egg joins a sperm it has an inherent, unrevokable right to exist, the circumstances of the conception *do not matter.* I would carry this thought through to say that if you then say that women who have been raped have a right to abortion because they didn't choose to have sex, or because of the violation of the rape, then that tells us that your anti-abortion position hinges on whether women have been punished enough, a "you made your bed, you have to lie in it" perspective that is more about imposing your own ideas about how much women should be made to suffer and what consequences you think they should be forced to experience for having sex, rather than a pure idea about the sanctity of life.
- Finally Leslie Cannold at TEDxCanberra on abortion and shame, found via Viva la Feminista. It's really smart and awesome.
Note: Whenever I mention Vanderbilt, that's my personal opinion, not anything official on behalf of the university. Most people are smart enough to understand that, but I like to make it explicit.


text:
A Look Back and a Look Forwards at KDE 3.3
Chris Dunphy wrote a nice four page KDE 3.2.1 Review in March which we obviously missed and which imo hasn't received the attention it deserves yet. On the other side we were notified by "illogic-al" that he has written a short "What's New, KDE 3.3 Preview" based on KDE 3.3 Alpha. The first KDE 3.3 Beta with more completed features is expected to be released in about one week.
Language feature
One feature in KDE 3.3 that is not mentioned in the article is a change in language evaluation.
This is especially useful for smaller languages like Low Saxon where the rest of the translation of a program can be filled up with standard German.
Another (quite stupid) example from bugs.kde.org:
If you then start kmail as a standalone program you get in in Ukrainian. When you launch it via kontact, KDE finds out that Kontact is not translated into Ukrainian and uses Russian for kontact and all its submodules.
This is now fixed.
Heiko Evermann
By Heiko Evermann at Fri, 2004/06/25 - 5:00am
Re: Language feature
There is quite a bunch of new features not mentioned in the article if you compare it with the feature plan. It honestly only scratches a little bit on the surface.
Re: Language feature
Low saxon? This sounds pretty cool. Is there a screenshot available.
Language order and fallback solution.
What I believe however is that language string contribution has to be made easier for ordinary users that are not skilled in Programming. This may help to fix the problem which in fact is lack of contributions.
By hein at Fri, 2004/06/25 - 5:00am
Re: Language feature
Wouldn't it be nice if you were able to contribute to translations in a web page, wiki style? Hummm must think more about this. Or imagine that you are running a program that is not fully translated, you see a string that is not correctly (or not at all) translatted, you click Help->Tranlate String, the cursor changes, you click were the untranslated string is, and you are redirected to this wiki-style tranlation page, or the po file is opened for editing and when you click save the diff is uploaded to a server for review.
By P.Alves at Sat, 2004/06/26 - 5:00am
Re: Language feature
> What I believe however is that language string contribution has to be made
Well there is KBabel. No need for any programming skills. How much easier is it supposed to get?
By Christian Loose at Mon, 2004/06/28 - 5:00am
I absolutely agree with the guy who wrote the kde 3.3 preview about the kwallet thing. It must be me, but I hadn't found the option to disable it yet (there might be something wrong with my configuration though).
By Jelmer at Fri, 2004/06/25 - 5:00am
Re: Kwallet
Indeed, he's absolutely right. Nothing is more frustating than the requirement to type your password _every_ time after logging in (because of Kopete). I know it's not very safe to built in a "remember my KWallet password" option, but usability-wise this option is absolutely needed.
By Niek at Fri, 2004/06/25 - 5:00am
Re: Kwallet
Infact, "remember my KWallet password" is not very unsafe either. I need to supply my password atleast once to log in KDE, so why do i need to re-authenticate myself again and again?
By Nilesh Bansal at Fri, 2004/06/25 - 5:00am
Re: Kwallet
I put up with this myself, in case someone walks up to my PC while I'm not there (you could say my fault for not locking it before leaving, I suppose).
In future the threat of malware on Linux may become more serious, in which case measures like this will be more important.
By Paul Eggleton at Mon, 2004/06/28 - 5:00am
Re: Kwallet
kwalletmanager, Settings/Configure Wallet..., [ ] Enable the KDE wallet subsystem
Re: Kwallet
Personally, I think the best approach would be a simple PAM module that would try using the user's password to unlock the wallet. This would be, IMHO, the easiest way to make this happen. Then, it is just a matter of adding the option to the 'kde' pam config file.
If I knew how to write something like this, I would have already.
By chris at Fri, 2004/06/25 - 5:00am
Re: Kwallet
PAM is not everywhere.
By Mathieu Jobin at Fri, 2004/06/25 - 5:00am
Re: Kwallet
But where it is, this is a good idea.
By Bausi at Sat, 2004/06/26 - 5:00am
Re: Kwallet
Infact it is on almost every serious distro that is build these days.
on other platforms that don't support it you could still go the other way around. (or write something that fits better into that platform. having access to your own password hashes is a bad thing because email scripts, internet scripts, bash scripts, whatever script can send them up the internet to the hacker of choice, so he can brute force them.
security most always be done by external tools.
By Mark Hannessen at Mon, 2004/06/28 - 5:00am
Will there be full support for real SVG-icons in KDE 3.3? Or is there a possibility to use SVGs in KDE 3.2.3? :-(
By Sebastian Greiner at Fri, 2004/06/25 - 5:00am
Re: Student sorry >>> SVG / Kitchensync
Sorry, I wrote my "title" in the form... :-o
By Sebastian Greiner at Fri, 2004/06/25 - 5:00am
Re: Student
Well... I'm working on a set as we speak (Reinhardt, found at kde-look.org), and apart from a few graphical glitches, it works just fine in 3.2.2 :)
By Dan Leinir Turt... at Fri, 2004/06/25 - 5:00am
Re: Student
Well, in fact the Reinhardt icons work a little *too* well...
Here are the bug reports:
I think the KCM bug and the icon selector one are probably related, and fixing one will probably fix both issues.
By Luciano at Fri, 2004/06/25 - 5:00am
Simone Gotti started to implement a kitchensync konnector for IrmcSync. I've never used it myself, since I lack the phone to use it with, so I don't know exactly what's working already and what not. But in theory it should work with a T630.
You can find it in the CVS of kdebluetooth (kdeextragear-3). Compilation is disabled by default at the moment, since it depends on KDE 3.3.
AFAIK Simone is a bit short of time at the moment. I'm sure he will appreciate any help offered to make SonyEricsson/Siemens mobile phone users happy by completing the konnector ;)
By Fred Schättgen at Sat, 2004/06/26 - 5:00am
Re: IrmcSync
Thanks for telling me about this IrmcSync-Feature. But I couldn't find a RPMed Version of kdebluetooth with this integrated.
By Sebastian Greiner at Mon, 2004/06/28 - 5:00am
Re: IrmcSync
By brenton at Mon, 2004/06/28 - 5:00am
Weren't most of the other appearance-related KCM's supposed to be hidden once the theme manager was moved out of kdenonbeta? I've been waiting patientially for someone to do that for some time :-)
By smt at Fri, 2004/06/25 - 5:00am
Re: Redundancy..
Yup, shame on me :( Still on my TODO
By Lukas Tinkl at Fri, 2004/06/25 - 5:00am
Re: Redundancy..
Please also fix the size of the buttons in the theme manager.
theme manager
"get new themes" and "install themes" sounds very similar.
This might create confusion.
By hein at Fri, 2004/06/25 - 5:00am
Re: theme manager
Don't think so. None necessary involves the other.
I never had a problem with the kdm pictures (I like being a stylised dragon thank you very much), but what bugs me is that in 3.2 the option to edit the session list in kcontrol seems to have gone missing. So I can no longer log into xfce from kdm. Anyone else have this problem?
By Michael Donaghy at Fri, 2004/06/25 - 5:00am
Re: kdm
The 3.2 Kdm is supposed to automatically find all of your installed window managers and destkops, and display them in the appropriate login menu. If XFCE is not displaying, it's either because you don't have it installed, it's installed under a name Kdm doesn't recognize, or Kdm doesn't know about XFCE.
By David at Tue, 2004/06/29 - 5:00am
what a bad reviewers
First one keep complaining about small issues which are really subjective.
like the default look. I'm sorry, but I like life and bright color. It's what make KDE and Apple different from all other boring interface like Gnome and Windows.
Working on a computer is not only for boring gray guy wearing a tie.
I like curves, forms, movement, like cars and womans ;)
BUT WHO CARES !!! Its what makes Linux so great... use whatever you prefer. It's available to you. Keeping complaining about default look all along the review does not makes it a good review. Really boring to read.
For the orange and yellow in kmail, If I understood correctly what he was talking about ... The orange is customizable in colors, and the yellow is to show SECURITY RISK !!! Which MUST jump in user's eyes.
well, whatever.
and the second one... way more positive.. but unreadable...
whatever, hopefully this review won't make peoples laugh out of KDE.
KDE is way better, however how it looks on your particular setup.
By Mathieu Jobin at Fri, 2004/06/25 - 5:00am
Re: what a bad reviewers
>I like life and bright color. It's what make KDE and Apple different from all
Windows is gray and doesn't have bright colours? Are you colour blind, or are you using a monochrome monitor?
Windows has colours which are much brighter than MacOS, and this is why MacOS does not look like a kids' desktop.
By oliv at Tue, 2004/06/29 - 5:00am
Re: what a bad reviewers
About the review. You're right. It was unprofessional and did contain inside jokes, but the point was really to do a professional review. It was just one user's (mine) perspective on what i thought about certain things in the upcoming release and a chance to show screenshots to those who haven't seen it before.
By illogic-al at Tue, 2004/06/29 - 5:00am
Noatun >> /dev/null
With apparently both Juk and Amarok now in KDE 3.3, can someone enlighten me as to what the use, purpose or reason is for allowing any further existence of Noatun?
Look at the "freaking" Noatun website for a good laugh: http://noatun.kde.org/news.php#NoWereNotStillAlive "The primary reason nothing is happening here at noatun.kde.org is that we noatun developers consider noatun so close to completion it's not worth discussing."
In the mean time, are we supposed to wait for coders send from "above" to code heavenly plugins which are not likely to become default in 10 years and not likely to ever ex-hist in the first place, given developers and users are 'embracing' Juk and Amarok?
Is there some hidden secret agenda behind Noatun which is going to blow all our minds away in one big global awe? Please enlighten me as to why Noatun is even allowed to be in KDE anymore.
Just curious.
By ac at Sat, 2004/06/26 - 5:00am
Re: Noatun >> /dev/null
amaroK is not in KDE 3.3
Re: Noatun >> /dev/null
Too bad, I would prefer it over Noatun ..as you might have noticed. I don't think I am the only one with 'bad feelings' over this whole Noatun thing.
Whats so great about Noatun?
By ac at Sat, 2004/06/26 - 5:00am
Re: Noatun >> /dev/null
I completely agree. And everytime something like this is mentioned, nobody speaks up saying "I actually like noatun". And for those of you who do like noatun - I hope this was enough to make you reply ;-). I just use mplayer, kmplayer, kaffeine or xmms.
By affenschlaffe at Sat, 2004/06/26 - 5:00am
Re: Noatun >> /dev/null
I also agree.
BURN Noatun, BURN!
By foljs at Tue, 2004/06/29 - 5:00am
Re: Noatun >> /dev/null
I actually like noatun. But then, I don't like mp3.. ;)
By teatime at Tue, 2004/06/29 - 5:00am
Re: Noatun >> /dev/null
Well, here I am, I actually like noatun. I use kaffeine for playing videos, but I think it is an overkill for music. I use "wake up" plugin as my alarm clock (haven't found a single decent alarm clock program yet). noatun is simple, lightweight and full featured. May be I will change my opinion once I try amarok, this thread is definitely reason enough to go and compile it. So far I didn't look for an alternative music player, since despite a few minor annoyances, I found noatun to be a very nice program.
By Jeld The Dark Elf at Sat, 2004/07/03 - 5:00am
Re: Noatun >> /dev/null
actually i would replace juk with amarok immediately. juk is so much worse...now when amarak reached stable 1.0 it should replace juk in kmultimedia
By yemu at Tue, 2004/06/29 - 5:00am
Re: Noatun >> /dev/null
kaffeine does everything i need.
including MP3, party animation, playlist, movies
By Mathieu Jobin at Sat, 2004/06/26 - 5:00am
Still with Arts? + kwin&konqueror crashes thoughts
Hello ! It looks like KDE 3.1 to 3.2 had much more changes than KDE 3.2 to 3.3 doesn't it?
Anyway, it's wonderful that Chris' just one more time telling us what's new in the next KDE version ;-).
Chris mentions: " Kwin has suffered the occasional inexplicable death. You never really fully appreciate the term "Window Manager" until it's crashed and you realize just how much it does."
I totally agree with you man ! I've even suffered kwin crashes in KDE 3.2.x stable versions, and ended up filling a feature request, where I suggest the best possible solution: If the WM crashes, KDE should restart it smartly: http://bugs.kde.org/show_bug.cgi?id=82277 .
I'm happy you still hadn't any konqueror crash, because in FC1 + KDE 3.2.2 it likes crashing a lot =). I have filled a bug report that suggest a solution with a similar approach to the last one; this time the fix would be to ask the user if he want to recover last session when it opens a new konqui's window and it has just crashed. You can read the report in http://bugs.kde.org/show_bug.cgi?id=83803 .
Finally, Chris mentions that he configured gstreamer output in amaroK. I'm a tad curious: wasn't KDE 3.3 supposed to replace arts with other Sound System ? I think It would be sad if we continue with arts for another KDE big version; every other Sound Library I've used so far has worked better than it here. I think that I'm most probably wrong and the challenge was for KDE 4 :P.
By edulix at Sat, 2004/06/26 - 5:00am
Re: Still with Arts? + kwin&konqueror crashes thoughts
> It looks like KDE 3.1 to 3.2 had much more changes than KDE 3.2 to 3.3 doesn't it?
Is this surprising when you look at the development time which is only the half of the KDE 3.2 cycle?
Re: Still with Arts? + kwin&konqueror crashes thoughts
> I'm a tad curious: wasn't KDE 3.3 supposed to replace arts with other Sound System?
No. We've never intended to replace aRts in the KDE 3.x series since it's required for binary compatibility with previous releases. We will most likely switch to another system for KDE 4.
By Scott Wheeler at Tue, 2004/06/29 - 5:00am
um. chris? [was Re: Still with Arts? ]
By illogic-al at Tue, 2004/06/29 - 5:00am
Kde rocks
every kde release has had "a must have" something since I started using kde 1.0
This time the there are many many interesting features including:
Anti Spam Wizard
keep up the good work kde!
By Mark Hannessen at Mon, 2004/06/28 - 5:00am
Re: Kde rocks
If you take a look at Kommander you might decide it is worth putting on that list. It is somewhat revolutionairy in it's approach to bringing application extention through DCOP and rapid small application development to users and scripters. It is in the kdewebdev module.
If there is something missing in KDE you want you might find yourself building it in a few hours some night. ;-)
By Eric Laffoon at Mon, 2004/06/28 - 5:00am
Re: Kde rocks
I agree kommander is looking very very cool,
By Mark Hannessen at Mon, 2004/06/28 - 5:00am
Noatun, Juk, Amarok, kedit, kwrite...
What I'm finding kinda disturbing in KDE lately is the repetition of applications, can we just leave one application for each tasks... I don't know about Noatun, Juk and Amarok, but about kwrite and kedit... when will kedit will be removed ? My simple market researching shows that application redundancy confuses people.
By Pupeno at Mon, 2004/06/28 - 5:00am
Re: Noatun, Juk, Amarok, kedit, kwrite...
My understanding was that KEdit will disappear as soon as the part that KWrite uses supports bi-directional text. So it's an i18n issue. If you are compiling from source you can use DO_NOT_COMPILE to remove certain applications anyway.
I agree in general that there should be some consolidation, particularly in the areas of image viewers and media players. There are also quite a few little applications that I suspect nobody uses or even finds because they are stuck in the "more applications" subfolders in the K menu.
By Paul Eggleton at Mon, 2004/06/28 - 5:00am
Re: Noatun, Juk, Amarok, kedit, kwrite...
> as soon as the part that KWrite uses supports bi-directional text.
And this support is said to be implemented much easier with Qt 4.
By Anonymous at Mon, 2004/06/28 - 5:00am


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text: Monday, April 08, 2013 Study: Physical Therapy Beneficial to Critically Ill Patients According to a new systematic review of the evidence base for exercise in critically ill patients, physical therapy in the ICU appears to confer significant benefit in improving quality of life, physical function, and peripheral and respiratory muscle strength; increasing ventilator-free days; and decreasing hospital and ICU stay. "It is apparent that survivors of critical illness experience poor physical, functional, and cognitive outcomes often lasting for years," said the authors of a paper published in Critical Care Medicine, noting that this condition, "post intensive care syndrome," and the related "intensive care unit acquired weakness" can result in major impacts on the health and productivity of survivors and caregivers, availability of hospital beds, and health care costs. "Early physical therapy in intensive care in increasingly recommended, and this review has found preliminary evidence that there are beneficial effects," the study said. The researchers analyzed 10 randomized control trials and 5 systematic reviews after identifying 3,126 abstracts (1980 through January 2012) from a keyword search using "critical care" and "physical therapy" and related synonyms. Overall there was a significant positive effect favoring physical therapy to improve quality of life (g = 0.40, 95% confidence interval 0.08, 0.71), physical function (g = 0.46, 95% confidence interval 0.13, 0.78), peripheral muscle strength (g = 0.27, 95% confidence interval 0.02, 0.52), and respiratory muscle strength (g = 0.51, 95% confidence interval 0.12, 0.89). Length of hospital stay (g = -0.34, 95% confidence interval -0.53, -0.15) and ICU stay (g = -0.34, 95% confidence interval -0.51, -0.18) significantly decreased, and ventilator-free days increased (g = 0.38, 95% confidence interval 0.16, 0.59) following physical therapy in the ICU, the study says.


text:
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Copyright 2020 Sussex County Association of REALTORS®, Inc.


text:
Tagged: MLB.com
Four Corners, Angels, Mets, Marlins, Dodgers, Oh My! …Or, Not a Slow News Week
So let me get this straight. Tyler Chatwood is batting 1.000 (In addition to pitching a great game!). Jered Weaver is a beast even with precious little run support – six punch outs and 20 first pitch strikes on 28 batters! Torii Hunter is the run support – both RBIs on Monday were Torii! The bats are waking up, including Vernon Wells' – he's batting .292 with seven RBIs and three homeruns on this road trip so far! And Maicer Izturis is the Rally Monkey. Well, it sounds like everything is working out alright to me.
The Angels redeemed themselves against the Mets in game three and then, in their next stop on the Four Corners Road Trip, went on to win game one against the Marlins. Things seem to be falling back into place again in the sense that each component of the Angels' game has been strong enough that some of the parts are able to take the slack for another part, when that part fails. No offense on Monday? Weaver's pitching, the bullpen and the defense carried the day. Scary bullpen on Sunday? No problem. Again, starting pitching, this time Chatwood's, and the offense, also including Chatwood not to mention Wells, Peter Bourjos, Jeff Mathis and several others – built up enough of a lead that it all worked out. Keep it up guys and we might have ourselves a pretty good streak going!
However, I was amused to look at headlines on MLB.com last night and discover that somehow, we may have beat the Marlins but somehow we also lost to the Braves last night:
Hmmmm…what exactly are they saying here? That Tim Hudson is so good, he single handedly beat the Blue Jays and a team the Braves weren't even playing? Or is this a Freudian commentary on the Angels chronic lack of run support? The headline was corrected this morning, and possibly even moments after I noticed it. But notice it I did, and it was too funny to to share with you all…and now I sincerely hope MLB never takes a comedic look at the typos and crimes against commas I have committed on this blog, LOL.
Bud Selig Tells Frank McCourt "No" and "Bad Dog" and Rubs His Nose in it…So He Learns
Actually, as you all probably know, it went a bit beyond that. The deal with Fox that Bud Selig rejected yesterday was the last possible call from the governor that Frank McCourt had any hope of hearing. And even though it makes things a little rougher still for the Dodgers right now, I could not be happier. Selig, as quoted in the MLB.com article really said it best: Critically, the transaction is structured to facilitate the further diversion of Dodgers assets for the personal needs of Mr. McCourt. Given the magnitude of the transaction, such a diversion of assets would have the effect of mortgaging the future of the franchise to the long-term detriment of the club and its fans.
As a baseball fan, and as a lady who rooted passionately for the Dodgers in childhood, the last few seasons under the Mommy Dearest like affections of the McCourts have made me ill. The Dodgers are one of the most storied franchises in baseball and their fans are great people. I may give my friends and family good-natured crap and about leaving the game before the 8th inning, but Dodger fans are a passionate, knowledgeable, blue-bleeding bunch and they do not deserve the past few years' treatment any more than the players do. The only hope the Dodgers have of full and lasting recovery from this particular abusive relationship, is if the McCourts are no longer in the picture.
So, citizens of Dodgertown, (hey, I get your emails and read your billboards from time to time) I tip my glass to you with the sincerest hopes that this is the beginning of much, much better things to come for you. Perhaps even eventual ownership by Steve Garvey and Orel Hershiser, which is the rumor I most hope is true. My glass is full of coffee, mind you, because it's the middle of the day and all that. But, really, it's the thought that counts! I even wish you a long and fruitful winning streak…starting in about two weeks. 😉
Post Tuesday Game Edit:
Okay. Granted the Marlins had just lost 11 in a row. Rationally there were going to win one eventually. But why do I feel like the Angels are the slump buster team of the American League, temporarily on loan to the National League? Overreacting? Just a tad. Which is why I typically don't post immediately following a game. We'll get 'em tomorrow. But still! Five to two? Shut out until the ninth inning? Really? Guys. When I talked about keeping it up and getting a streak going, this is pretty much the antithesis of what I was talking about…and by pretty much, I mean exactly.


text:
The new effort was spurred in large part by the growing influence of Latino voters who strongly backed President Obama and other Democrats in November.Interesting how that energizes both parties to act. A fascinating political game, which includes not only the reform itself but also — whether the reform occurs or not — the way various political actors look as they relate to the proposal for reform. It's sure to be a garish spectacle. In this political theater, who's most likely to take pratfalls on the public stage?
The senators are expected to call for normalizing the status of the nation's 11 million undocumented immigrants, including allowing those with otherwise clean criminal records to obtain legal work permits, officials said. The group is also likely to endorse stricter border controls and a better system for employers to verify the immigration status of workers.Here's a chance for Republicans to stop being "the stupid party" — as Bobby Jindal advised recently — and to become the truly smart party. Don't appeal to fears. Don't resort to ideology. Actually figure out the right answer on the basis of sharp economic thinking, and be prepared to explain it clearly. It seems to me, we have 11 million undocumented immigrants working in this country because they are serving our needs. My hypothesis is: We don't kick them out because we want them here, whether we admit it to ourselves or not. That's why we don't get tough. We still talk about getting tough and kicking them out — and walling out additional migration — because that appeals to emotion and tracks habitual thinking. But what's really happening? What have we really been doing all these years? How can we align the official policy with reality? That's how I'd like to see Republican politicians sharpen up, become the smart party, and show leadership.
It was not clear, however, whether the final agreement will offer guidance on perhaps the thorniest issue in the immigration debate: what mechanism illegal immigrants could use to pursue full citizenship.


text:
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text:
Western blot analysis of extracts from various cell lines using Sec23A Antibody.
|Product #
|100 µl
|$ 268
|H M R Mk
|MW (kDa)
Product Information
|Western Blotting
Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol. Store at –20°C. Do not aliquot the antibody.
For western blots, incubate membrane with diluted primary antibody in 5% w/v BSA, 1X TBS, 0.1% Tween® 20 at 4°C with gentle shaking, overnight.
NOTE: Please refer to primary antibody datasheet or product webpage for recommended antibody dilution.
From sample preparation to detection, the reagents you need for your Western Blot are now in one convenient kit: #12957 Western Blotting Application Solutions Kit
NOTE: Prepare solutions with reverse osmosis deionized (RODI) or equivalent grade water.
Load 20 µl onto SDS-PAGE gel (10 cm x 10 cm).
NOTE: Loading of prestained molecular weight markers (#13953, 5 µl/lane) to verify electrotransfer and biotinylated protein ladder (#7727, 10 µl/lane) to determine molecular weights are recommended.
NOTE: Volumes are for 10 cm x 10 cm (100 cm2) of membrane; for different sized membranes, adjust volumes accordingly.
* Avoid repeated exposure to skin.
posted June 2005
revised November 2013
Reprobing of an existing membrane is a convenient means to immunoblot for multiple proteins independently when only a limited amount of sample is available. It should be noted that for the best possible results a fresh blot is always recommended. Reprobing can be a valuable method but with each reprobing of a blot there is potential for increased background signal. Additionally, it is recommended that you verify the removal of the first antibody complex prior to reprobing so that signal attributed to binding of the new antibody is not leftover signal from the first immunoblotting experiment. This can be done by re-exposing the blot to ECL reagents and making sure there is no signal prior to adding the next primary antibody.
NOTE: Prepare solutions with reverse osmosis deionized (RODI) or equivalently purified water.
posted June 2005
revised October 2016
Protocol Id: 10
This protocol is intended for immunoprecipitation of native proteins for analysis by western immunoblot or kinase activity utilizing Protein A magnetic separation.
NOTE: Prepare solutions with reverse osmosis deionized (RODI) or equivalent grade water.
10X Cell Lysis Buffer: (#9803) To prepare 10 ml of 1X cell lysis buffer, add 1 ml cell lysis buffer to 9 ml dH2O, mix.
NOTE: Add 1 mM PMSF (#8553) immediately prior to use.
A cell lysate pre-clearing step is highly recommended to reduce non-specific protein binding to the Protein A Magnetic beads. Pre-clear enough lysate for test samples and isotype controls.
IMPORTANT: Pre-wash #73778 magnetic beads just prior to use:
Carefully remove the buffer once the solution is clear. Add 500 μl of 1X cell lysis buffer to the magnetic bead pellet, briefly vortex to wash the beads. Place tube back in magnetic separation rack. Remove buffer once solution is clear. Repeat washing step once more.
IMPORTANT: The optimal lysate concentration will depend on the expression level of the protein of interest. A starting concentration between 250 μg/ml-1.0 mg/ml is recommended.
IMPORTANT: Appropriate isotype controls are highly recommended in order to show specific binding in your primary antibody immunoprecipitation. Use Normal Rabbit IgG #2729 for rabbit polyclonal primary antibodies, Rabbit (DA1E) mAb IgG XP® Isotype Control #3900 for rabbit monoclonal primary antibodies, and Mouse (G3A1) mAb IgG1 Isotype Control #5415 for mouse monoclonal primary antibodies. Isotype controls should be concentration matched and run alongside the primary antibody samples
Proceed to one of the following specific set of steps.
NOTE: To minimize masking caused by denatured IgG heavy chains (~50 kDa), we recommend using Mouse Anti-Rabbit IgG (Light-Chain Specific) (D4W3E) mAb (#45262) or Mouse Anti-Rabbit IgG (Conformation Specific) (L27A9) mAb (#3678) (or HRP conjugate #5127). To minimize masking caused by denatured IgG light chains (~25 kDa), we recommend using Mouse Anti-Rabbit IgG (Conformation Specific) (L27A9) mAb (#3678) (or HRP conjugate #5127).
posted December 2008
revised April 2018
Protocol Id: 410
Sec23A Antibody recognizes endogenous levels of total Sec23A protein.Species Reactivity:
Human, Mouse, Rat, Monkey
Polyclonal antibodies are produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Phe717 of human Sec23A protein. Antibodies are purified by protein A and peptide affinity chromatography.
There are two isoforms of Sec23 protein: Sec23A and Sec23B. Both isoforms have been shown in the Sec23/24 complex, which is a component of COPII coat (1). COPII is composed of at least five proteins: the Sec23/24 complex, the Sec13/31 complex, and Sar1. COPII coat is located at the ER/Golgi interface and involved in transport of newly synthesized proteins from the ER to the Golgi apparatus (2). COPII formation is initiated through binding of the activated G protein, Sar1, to the Sec23/24 complex to form a prebudding complex, which directly binds target molecules (2-4). The prebudding complex further recruits Sec13/31 to form mature COPII coat (5,6). In addition to being a COPII component, Sec23 has also been shown to interact with p125 and Sec16 at the transitional ER; these interactions are important for regulation of the COPII transportation function (7,8).
Explore pathways + proteins related to this product.
UniProt ID: Q15436
Entrez-Gene Id: 10484
Cell Signaling Technology is a trademark of Cell Signaling Technology, Inc.


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Performs routine and highly complex laboratory analyses on clinical specimens in various sections of the laboratory under supervision.
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Take Back the Night Event This Tuesday Night – Vanderbilt University, Nashville, TN
The students will also selling bath and body products at the event from and supporting Thistle Farms, run by the women of Magdalene House who are working to change their lives from a history of sex work or drug abuse. Here's some background from a previous post, and on Monday night Becca Stevens of Magdalene House/Thistle Farms will host a discussion on campus.
The details of TBTN at Vanderbilt, from a student organizer of the event:
Take Back the Night will have its first march in three years Tuesday, October 30 at 7:15 p.m. This is our night to come together as one strong body of students, faculty, and community members. Together we will assert that violence is preventable. We will stop the silence and end the violence that barrages us, afflicts us, and hurts us. Together, we will stand strong; every voice will be heard and resonate. We will come together to help one another gain the resources to prevent violence and combat it.
Please join us on Magnolia Lawn on Peabody Campus and march together to Alumni Lawn. There we will have sugary refreshments, a speaker, a performance by Vanderbilt Spoken Word, and an open microphone for students to express their sentiments about violence on campus and in their everyday lives. Everyone is welcome to attend, and this is TBTN-Vanderbilt's Human Identities event. Thistle Farms products will also be sold by the women of the Magdalene Project. We hope that you will attend and help us in our initiative to raise awareness and Take Back the Night!
Vanderbilt folks may also want to check out the campus TBTN group on Facebook.


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Capital Press
Idaho Power Co. is partnering with irrigators to expand its high-tech cloud seeding program into the Wood River watershed.
The utility is also investigating opportunities in the Boise River Basin and the Wyoming mountains at the headwaters of the Upper Snake River Basin.
Lynn Harmon, administrator with the Big Wood Canal Co., said his board has reached a three-year agreement with Idaho Power, budgeting $50,000 per year toward cloud seeding beginning this winter. Under appropriate conditions, Idaho Power will seed storms bound for the Big Wood and Little Wood basins with its King Air C90 plane.
Torches mounted on the plane or dropped from it burn silver iodide, spreading particles through clouds to attract water vapor and fall as snow.
Harmon plans to eventually supplement aircraft cloud seeding in the Wood River watershed with Idaho Power remotely operated propane generators, which burn silver iodide from high atop mountain slopes. His board members were impressed by an Idaho Power presentation, and the canal company retains the right to cancel the contract at any time.
In the Payette River watershed, where Idaho Power will continue using its plain in conjunction with 17 ground-based generators, the utility's modeling estimates cloud seeding has boosted annual snowfall by an average of 14.4 percent between 2003 and 2013, said Shaun Parkinson, Idaho Power water resources leader.
"Even a 10 percent improvement, that's a lot of dollars when you look at the potential crops you could raise," Harmon said.
Idaho Power has also installed seven high-resolution weather gages in the Payette, which will be put to use this winter to provide better data for fine-tuning the computer weather model used for basing cloud seeding decisions.
Though December was a dry month, Parkinson said Idaho Power conducted more seeding in November than during all of last winter combined. Idaho Power, which has a $1 million annual cloud seeding budget, started its program in 2003.
Idaho Power also has 19 remotely operated generators on the ground throughout the Upper Snake Basin, working in conjunction with Marty and Connie Owen with the private cloud seeding company Let it Snow.
Clark County contracts with Let it Snow on behalf of a group of about 40 contributing counties, irrigation districts, cities and other partners. The project has an annual budget of $165,000 but spent only $89,000 last season due to a lack of good storms to seed. The Owens hire farmers and other rural residents with high-elevation property to manually run 25 generators. They consult with Idaho Power meteorologists about when to seed. They've run generators for 275 hours this season and are budgeted for 6,000 hours. Models show Upper Snake cloud seeding improves snowfall by 3 percent on average.
"If you get even a 1 percent improvement, you've paid for the project," Marty Owen said.
In the Wood River watershed, Parkinson believes seven to 10 remotely operated generators would suffice. Idaho Power is also working toward an agreement with Boise River irrigators, where about 10 more generators would be needed.
Parkinson said Idaho Power will also pay close attention to a Wyoming state-funded study on cloud seeding, hoping to eventually seed in the Wyoming mountains near Idaho.


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What: Bilberry is any of several species of low-growing shrubs in the genus Vaccinium (family Ericaceae), bearing edible berries. The species most often referred to is Vaccinium myrtillus L., but there are several other closely related species (Wiki).
Bilberry fruit contains dense levels of anthocyanin pigments which experimental studies have shown possible links to lowered risk for diseases of the heart, cardiovascular system, eyes, and certain cancers. Bilberry extract has been used historically as a tonic to prevent some infections and skin diseases. Today the fruit is used to treat gastrointestinal issues, menstrual cramps, eye problems, varicose veins, and other circulatory problems. This does not include Bilberry leaf extract, which is used to treat entirely different condition (NCCAM).
Origin: Bilberries are found in very acidic, nutrient-poor soils throughout the temperate and subarctic regions of the world. They are closely related to North American wild and cultivated blueberries and huckleberries in the genus Vaccinium. One characteristic of bilberries is that they produce single or paired berries on the bush instead of clusters, as the blueberry does. The fruit can be eaten or made into extracts for topical use.
Products Found In: Facial moisturizers, treatments, anti-aging skincare, facial cleansers, toners/astringents, acne treatments, exfoliants, skin fading/lighteners, eye creams. (EWG).
Alternative Names: Vaccinium Myrtillus Extract, Bilberry Extract, Extract Of Vaccinium Myrtillus, Extract Of Whortleberry, Whortleberry Extract, Vaccinium Myrtillus (EWG).
Toxicity: Bilberry (Vaccinium myrtillus) is generally classified as non-toxic or harmful. (EWG).


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Model #CSS-1216C
|List Price:
|Our Price:
General Description
We're committed to exceeding your expectations:
- Found it for less? We'll match the price
- 25-Year or Limited Lifetime Warranty
Our customers come first — we guarantee it!
Determining the correct configuration and stage size for an event can be quite complicated. Comprehensive stage sets from AmTab are sized to suit a variety of purposes. This 12'x16' stage provides a large surface that is appropriate for public occasions.
Transform ordinary rooms into auditoriums, concert spaces or lecture halls with AmTab's EZ-Performance stages. Choose from a variety of sizes and heights to find the model that suits your space and needs.
These portable stages are built with heavy–duty square steel tubing for years of reliable use. Multiple units will stay attached as the built–in coupling⁄lock system securely locks level–to–level or dual–height arrangements.
With hardboard and carpet top possibilities, these durable stages are appropriate for dance recitals, commencement exercises, training sessions and conferences. Need a different set–up for a new event? Portable stages can be configured and reconfigured to accommodate different purposes.
- Manufacturer:
Over the past 50 years, AMTAB Manufacturing has developed the classic folding table to a whole new level. Creative innovations such as fold and roll, stow-away, convertible table-bench units and more make AMTAB's products the ideal solution for any multi-tasking institution.
- Width:
- 192 in.
- Depth:
- 144 in.
- Height:
- 24 in.
- Weight:
- 1275 lbs.
- Deck Surface Material:
- Carpet
- Green
- MAS Certified LEED
- Warranty:
- Limited Lifetime
- Weight Capacity:
- 250 Lbs. Per Square Ft.
- Made in USA
- Certified Green
- High Visibility: 24"–tall stage can be seen from far away.
- Time Saver: Comprehensive package eliminates the time–consuming task of coordinating separate stage pieces to fit desired dimensions. Package includes: Stage sections, guard rails, skirting, and one set of stairs.
- Decreased Distractions: Carpeted platform minimizes noise from movement on stage.
- Great Size: 12'x16' stage accommodates band performances as well as ceremonies.
- Versatile: Portable stages can be rearranged as needed. Great for lectures, performances, graduations and more.
- Easily Mobility: Each stage section has heavy-duty casters on two of its legs for easy mobility. Using the special caddy, stage units can be rolled from the storage area to the event site in a single trip, and unloaded without any heavy lifting.
- Surface Options: Individual stage sections offered in carpet top as well as hardboard top. Comprehensive stage sets available with carpet top only.
- Built to Last: Constructed from heavy–duty square steel tubing.
- Secure Attachment: Built in coupling system locks level–to–level or dual–height arrangement.
- Size Selection: Available in a variety of lengths, widths and heights. Individual and comprehensive packages available.
- Lifetime Coverage: Our Limited Lifetime Warranty guarantees many years of use and enjoyment.
This product is made with pride in the United States of America!
MAS Certified Green (compliant with LEED for Schools)
We're committed to exceeding your expectations:
- Found it for less? We'll match the price
- 15-Year or Limited Lifetime Warranty
Our customers come first — we guarantee it!
Shipping & Assembly
- Ships Via:
- Common Carrier
- Leaves Factory In:
- Approximately 8-9 weeks
- Assembly:
- Ships assembled
Portable Stage Set Carpeted
|List Price:
|Our Price:
Product Family
This product is a part of EZ-Performance Portable Stages by Amtab
There are 46 products in the family


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Giovanni Hot Chocolate Sugar Scrub
Hot Chocolate Sugar Scrub sweetens your day as a warming gentle body exfoliator that polishes skin's surface, removing cellular debris. The richly scented formula contains the exclusive Giovanni Pure Organic Technology blend, an advanced essential oil complex to soothe, smooth and regenerate skin all over. Includes essential fatty acids necessary to smooth, repair and help heal skin. What an intoxicating experience. Feel relaxed. Vegan and cruelty free. All Giovanni products are sulfate-free. Available in 9 oz jar.
*Sucrose (Sugar), Carthamus Tinctorius (Safflower) Seed Oil, Polysorbate 20, Silica Dimethyl Silylate, Aleurites Moluccana (Kukui Nut) Oil, Butyrospermum Parkii (Shea Butter) Oil, Tocopheryl Acetate (Vitamin E), Juglans Regia (Walnut) Shell Powder, *Aloe Barbadensis (Aloe Vera) Leaf Juice, *Honey Extract, *Prunus Amygdalus Dulcis (Sweet Almond) Fruit Extract, *Macadamia Ternifolia (Macadamia) Seed Extract, *Theobroma Cacao (Cocoa) Seed Butter, Fragrance (Includes Essential Oils)
*Certified Organic
Recommended Use:
- Under a warm shower, dip into jar and then rub across body to exfoliate all over.
- Rinse and feel the warmth rush through you.
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I am floating, arms and legs suspended, in a lake of salt. A layer of thick black mud is caked on my skin, melting away in what feels like warm bath water. I am surrounded by buoyant tourists, most of whom are also wearing masks and sleeves of clay. We are relaxing in nature's spa, under the heat lamp of the Israeli sun.
The Dead Sea, rich in chloride salts of magnesium, sodium, potassium and bromine, is the lowest point on earth in any land mass – 423 metres below sea level. Since the quantity of water that evaporates from the lake (it's not really a sea) is greater than that which flows in, it has the highest concentration of salt in the world – almost nine times more salt than the ocean. Its high density prevents me from sinking, no matter how hard I try.
This vast stretch of water on the edge of the Judean Desert boasts several beaches and large tourism centres that offer pampering services to guests, at a cost. Although sparsely populated and serenely quiet in the modern day, the area is believed to have been home to the biblical cities of Sodom, Gomorrah, Adman, Zebouin and Zoar.
The sea is considered "dead" because its extreme salinity prevents fish and aquatic plants from living in it. That same salt, on the other hand, offers relief to visitors suffering from a variety of ailments such as psoriasis, eczema, sinusitis and osteoarthritis. Famous for its healing powers, the Dead Sea has been dubbed "the lowest health spa in the world." The composition of the water's salts and minerals, along with the skin-soothing mud that rests on its floor, make this lake especially therapeutic.
To maximize our experience, my friends and I slather each other with the viscous mud that has been conveniently set aside for our organized group of young professionals. We learn that the tar-like substance relieves tensions of mind and muscle, accelerates natural exfoliation and cleanses toxins from pores. The female participants are even more excited to hear that massaging the mud on areas with cellulite stimulates blood circulation and, in turn, flattens out the cottage-cheese bumps. We let the mud harden for about 30 minutes in order to reap its full benefits.
Hundreds of bikini- and Speedo-clad tourists populate the beach on this August afternoon, lounging on the sand and resting their limbs in the water. With no effort required to stay afloat, some even read a newspaper or magazine. Our group is now scattered, but my friends and I decide to wade into the lake and assume our reclining positions. While we are cautious enough to avoid salt-to-face contact, other Dead Sea virgins are not. We witness several victims rushing to shore to soothe their burning eyeballs and rinse out their mouths.
Before visiting the Dead Sea, our tour guide had warned the women on my trip not to shave – stubble is preferable to salt stinging freshly nicked legs, he explained. We took his advice, and after being in the water, are thankful we sacrificed beauty for pleasure. We were not warned, unfortunately, that wearing an old bathing suit is a smart idea; the water discolours most fabrics.
Much like when you're in a bathtub for too long, your body tells you it's time to get out of the lake. I notice it doesn't take long to dry off in the sun, but I soon realize my floating adventure has left its mark on my skin. While the water has evaporated, the salt has not, and I am suddenly my own sea salt factory. Luckily, outdoor showers are available beach-side, and I take full advantage of the opportunity. For those who prefer to cleanse in chlorine, swimming pools are also available.
My Dead Sea visit would not be complete without a stop at one of the gift shops. I'm on a mission to buy some of the lotion created by a company called AHAVA, which means love in Hebrew. Dead Sea Laboratories, the only cosmetics enterprise situated on the shores of the Dead Sea, derives its raw minerals directly from this natural source for AHAVA's line of beauty, skin care and treatment products.
All AHAVA products contain a mineral skin osmoter – a unique active complex made of a high concentration of Dead Sea minerals, shea butter, rose hip oil, fruit acids and natural amino acids. This combination of organic ingredients helps nourish and retain the skin's moisture, resulting in a fresher, healthier and more youthful appearance. I can't wait to apply the cream to my previously mud-masked body, which is already revitalized.
Next stop is Masada, the site of the ancient mountain fortress of Herod the Great. With an option to climb the tedious trails leading to the top or to sit back and absorb the phenomenal views from inside a cable car, our group chooses the latter. We are, after all, freshly pampered.


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A growing body of literature is exploring whether and when actively managed funds are worthwhile. The studies are based on the groundbreaking work of Antti Petajisto who found that active funds do beat passive indexes—if one separates the "closet index funds" that call themselves active managers.
In other words, Petajisto found that close to a third of mutual funds are active in name only but actually collect the higher fees of active funds while hugging their benchmarks such that they perform like low-cost index funds, only less well (because of the drag of their higher fees).
A further 20% of funds are officially index funds, leaving just half of retail funds as genuinely active funds. Of those, Petajisto found that the most active funds tended to generate significant alpha for investors.
Now, a new study by three finance professors seeks to locate active managers' incentive for closet indexing.
Aron Gottesman and Matthew Morey of Pace University and Menahem Rosenberg of Touro College build on Petajisto's findings but propose data which they argue revises the way we regard the manager's incentive.
The researchers write:
"What is the incentive for active funds to closet index during down markets? According to Petajisto it is that underperforming the benchmark is particularly painful in a down markets when everyone is suffering losses, as opposed to an up market where the investors are still making money. Consequently a fund that underperforms in a down market will have lower net flows than a closet indexer. These losses in flows can cause the managers' compensation to fall as it is often tied to size of the net assets of the fund, or worse, cause the manager to be fired. To avoid these consequences it is in the manager's interest to closet index during down markets."
But in examining 15 years of open, retail, actively managed, no-load funds from 1997 to 2011, Gottesman, Morey (left) and Rosenberg observed that shareholders did not penalize active managers in down markets. Rather, they found that shareholders direct their fund flows to high-performing funds in up markets and penalize poorly performing funds in up markets, but they tend to leave things be during down markets.
The authors write: "Thus, while we find results somewhat different from what Petajisto theorizes, it still makes sense for a manager to closet index during down markets as outperformance is not rewarded. Indeed, why work hard to beat the market in down markets when it does not matter much for subsequently [sic] flows?"
Gottesman, Morey and Rosenberg specifically offer two alternative explanations for the manager incentive to closet index.
The first is based on an insight from behavioral finance which finds that investors feel the pain of loss more acutely than the joy of gain. For that reason, they are reluctant to sell losers.
"This theory works for our results as investors do not respond in down markets to out- or underperformance with subsequent future flows," they write.
A second rationalist explanation is that return dispersion is so great in down markets that investors attribute fund performance to luck rather than skill and consequently neither reward nor punish managers through subsequent fund flows.
In a phone interview with ThinkAdvisor, one of the study's authors, Mathew Morey, said he preferred the behavioral explanation while leaving the matter unresolved until clarified by future research.
Asked why just 30% of funds rather than a larger proportion of the 80% of funds that are officially actively managed don't resort to closet indexing, Morey thought integrity might have something to do with it.
"Maybe they have better corporate governance," he said, adding that he would be interested in studying the relationship between active share (i.e., funds that vigorously seek alpha) and Morningstar's fund stewardship ratings, which assess shareholder-friendly fund management.
Indeed, integrity is a core issue in Morey's study, which points out that closet indexing involves deception (since the funds purport to be active); higher fees—generally 100 to 200 basis points higher than index funds; and crucially, a loss of benefit to shareholders since it is precisely during down markets that actively managed funds tend to beat their benchmarks.


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Heaven Can Wait (1978) Directed by Warren Beatty & Buck Henry - *Astrid:* Ok, yes, there is a Warren Beatty fixation in our house. And a Julie Christie obsession too. *Heaven Can Wait* is a double-fix for desperate add...
7 years ago
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