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Video Transcript
Well it's a new year how many of you have made a new year's resolution. Some people have. You know I think about that and I know maybe you've made one or maybe you've made one in the past so you know what it's like to make a new year's resolution. And I got to tell you I don't make new year's resolutions anymore because they just don't work for me. And they really rarely work in my experience that talking to somebody I never hear anybody saying like, I did this in 1995 and I've been this way ever since.
You know why is it so hard why is it so hard to go a new way why is that so hard now in the gospel. We hear the story of the Magi and they encounter Christ and we hear at the end of the gospel they. They have encountered Christ and they have gone another way they didn't go back to Herod. They didn't go back the same way they came they went a new way in their life that's what happens when we encounter God. God challenges us we see in Scripture either you change and go with God or you go back to the old way. We see that in Scripture. We see that in Peter, we see that in the Apostles, we see that in the disciples and then we also see the reverse for people go back to their old way. Some of the towns that Jesus visited he goes back and he says what's happened. You know why aren't you guys following me went back to their old way are those people that he saw that he said you know let me go bury my my father first let the dead bury the dead he couldn't do it he couldn't follow Jesus. But the Magi the Magi go a new way they don't go back to the toxicity of Herod they don't go back to him.
You know I was reading this book friend of mine showed me this book and it's got this title and the title caught my eye this title it just leapt out at me it's called "Willpower Doesn't Work". And it just jumped out at me and you know when you you know there's something about us that. We know the truth in our heart and when we finally see it. You know maybe we haven't known it before but when we see it just resonates and it's just like that is so true I haven't been able to put words to it but that is so true willpower doesn't work. It doesn't work it doesn't work for me every time I try to work my willpower it doesn't work now and that's what I hear so often people say. We're under the illusion the lie that if just if our willpower was strong enough if it was just strong enough we could do it. Our willpower was just strong enough why is it that we can't change those big problems in our life. Our relationship problems if that's the case. Why is it that that we're not able to change our eating problems our smoking our drinking are any of those issues. Why is it that we have the inability to change our habits to set up prayer in our life are to exercise or to eat healthy. Why is it that we're not able to do that well this is what Benjamin Hardy says. This is he's a guy I wrote the book and he's in the bulletin. It's a really good book to read and he says our willpower is like a muscle and like a muscle we've always heard that it's like a muscle and guess what like a muscle it wears out. And like the muscle we're convinced if we build it up if we build it up we'll be able to do it if we just build up our willpower. Well you know what there are things that no matter how hard we work our muscles we will never ever be able to lift and that it is with our willpower. Those 5000 pound gorillas on our back just never gonna be able to lift that it doesn't work. So mr. Benjamin Hardy, you're so smart, what do we do now our willpower won't work he says something that there is one thing we can change. Our willpower will not work but there's one thing that we can change that will make the difference. Change your environment, that's the key, put people in your life who are supportive and knowledgeable about the change you want to make. Whatever that is put people in your life who know how to do that. Subtract those people that are supporting you in your negative behavior, subtract those people. Why will that work? Why will that work and not other things?
The Magi changed their environment they encountered Christ, they trusted their heart they followed the star to God because they knew that what was going to change them, God will power. By definition is our will power our will and our will does not work because by definition it is not God's will. It's our will power that's why it doesn't work. The Magi encountered God in Christ. Christ reveals to us that He is in everyone and so it is when we look for support from others that we are able to change. And I'm not saying to eliminate all negative people from our life, not saying that, it's just that we need to realize that those negative people are our ministry, and not our support. That we will never receive support from them maybe in a blue moon but we know if we want to be let down go to those people. But if we want to change, go to those people who are supportive that we experience God. In that is the challenge, change our environment I just want to give you one example one of the things that we as Christians suffer from it suffer from being overwhelmed.
Overwhelmed with taking care of other people that's good, as far as helping to take care of other people. But so many people lose themselves in that process. Not just Christians but caregivers lose themselves and they struggle they become depressed naturally and they know that they're supposed to be have some kind of life but they just don't seem to have the power to carve out a life for themselves. They're not able to say no. You know no is a complete sentence and I shouldn't be teaching you this because I should be guilting you to do all my work, but that's not healthy, that's not healthy and you will not be able to find yourself if you do that. We often think that we are the sole responsibility of caring for another person, need to wake up, you are not Jesus Christ. There is only one Savior and it's not me, or you. That we need help, that we need support and what we need in our life is a support group that's going to support us. Those people that are going to empower us in our life to be that positive energy, that positive force of helping us make decisions. One example for people who suffer from this one group is called al-anon. Now you might be saying, yourself well isn't it before Alcoholics you know people who deal with alcoholic. Yes, but they are also people in the main problem they have is not being able to say no. And they talk about their problems and that's the thing for us to be able to go to places support groups. That we can get honest about what's really going on and what we're really struggling with and what we really want to change. To go to those places that have those similar problems and speak to the solution of that. That's why they work that's why reading those self-help books don't work. That's what he talks about Benjamin Hardy there's all these books self-help and all their strategies and techniques and why do they hardly ever work. You know because they're not changing the environment it's why it doesn't work. There's all these groups we're looking for support men's groups women's groups there's one thing that I changed in my life, one little thing that I did that has changed my life completely, has change so many things you know what it is I joined a priest support group. I don't know how people live without support groups I don't get it. People come to me, it's like why isn't this working, try harder see if that works it doesn't because it's not the way we're made. I want you to make a new year's resolution let that new year's resolution be change your environment do that. Reach out to people who are supportive in the changes that we want to make and that's the thing. That it's in doing that we find that all things are possible for God and that's why it seems impossible for us right now. It doesn't mean that we're not going to have to face hard decisions, that we're not going to have to make courageous decisions. Yes we still will have to face those courageous decisions, but we will find that we are not alone, we will find the support the missing piece in our life that allows us to have the courage to make those decisions, you.


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La Sportiva
Men's Dawn Wall Jeans
La Sportiva Men's Dawn Wall Jeans
The La Sportiva Men's Dawn Wall Jeans are proper climber's jeans. The organic cotton and spandex fabric is highly comfortable, breathable, and stretchy, perfect for all day climbing, and features like an integrated lace-belt, a chalk bag loop, and zippered back pocket all work with your climbing gear. Pre-shaped knees also enhance mobility for even better movement.
Tech specs
|99% organic cotton, 1% spandex
|419 g (M)
• Adjustable waist (cord)
• Integrated loop on back part for chalkbag
• 2 back pockets
• 2 front hand pockets
• Integrated toothbrush pocket
• Integrated fob watch pocket
• Zipper back pocket
• Pre-shaped knees
• Unique CF press snap button closure
• Bluesign® certified

subset: commoncrawl


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Jun 09, 2017
How Video Production has Changed
Interview with Jake Harris Jake's been around the block in the video production industry, and has noticed some of the big changes in the last few years. 5 years ago, equipment wasn't nearly as advanced as it is today, there was no "standard way of shooting", and it was harder to see the difference in
May 31, 2017
So You've Booked A Video With Visual Domain
So you are going to be in a video! Presenting on camera is often the thing our clients are most nervous about, especially those without any on camera experience. We are here to tell you… Don't Stress! It is our job to make sure you are as comfortable and confident on camera as you can
May 03, 2017
Seven Video Innovations To Watch Out for In 2017
The world of video marketing is never static. Each year, new technology disrupts the way video is used to promote brands and products. Here are seven innovations you'll be experiencing a lot more in the coming year: Interactive video With more and more content available online, grabbing and maintaining the attention of potential customers is
With online video continuing to gain momentum, it comes as no surprise that everyone wants a slice of the action. But first things first. Do you know what gear your videographer will need to shoot a great video? We've opened up our videographer's toolkit to let you know what gear we regularly use and why
Apr 07, 2017
Marketing Trends For 2017 | Social Media
With marketing trends constantly in flux it can be hard to stay at the top of the game. One trend that is not going away anytime soon is social media videos. Brands and companies have cottoned onto the fact that when video is done right, it can be the winning factor of their social media
Apr 07, 2017
Live Action or Animation?
It is a pivotal question you need to ask yourself when first thinking of your company video. As the Creative Director for the Sydney office I have seen quite a few of both. Whilst each have their strengths and weaknesses, it is something that is so personal to each project that you have to weigh
Mar 21, 2017
Where (Social) Video Comes First
In 2016, Mark Zuckerberg said "We see a world that is video-first with video at the heart of all of our apps and services" and Visual Domain's ear pricked up. This was for two reasons; 1. If Zuckerberg is saying "across all apps and services" this means that there is going to be a big


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Guam's Positive Parents Together (GPPT)
Phone: 1-671-777-7991, 1-671-688-4968(4YOU)
Email: email@example.com
Website: https://guamparents.org/
Types of Services Offered: Child Support & Advocacy
Category: Non-Profit
- Description
- Services Offered
- Contacts
- Hours of Operations
- Website & Social Media
- Images, Videos, and other Files
- Other Info
Guam's Positive Parents Together (GPPT) is a coalition of parents who have children with different disabilities. We are working together to create one voice and one vision for disabled individuals on Guam. Our mission is to educate and train parents so they can be the very best advocates for their children in all areas of life.
Services Offered:
- Provide family to family or youth to youth support on an individual family or youth level (e.g., peer-to- peer, family support partners, parent navigators)
- Provide education to families or youth on issues of interest
- Provide training and mentoring of family members or youth (e.g., to assume leadership roles, act as provider, etc.)
- Participate in child serving system/system of care policy-making and leadership groups
- Participate in child serving system/system of care management meetings
- Provide advocacy
Ann Marie D Cruz, President
(671) 777-7991
Ovita Perez, Project Director
(671) 688-4968
P.O. Box 4297, Hagatna, GUAM, GUAM
Children, Teens, Adults
child support & advocacy, non-profit, coalition, parents, families, child, children, disabilities, education & training


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The Wastewater Treatment Research Unit focuses particularly on anaerobic digestion to produce methane from organic wastes, both solid and liquid, including on-line monitoring and control and has 30 years experience in this field and excellent facilities. The Research Unit is recognised nationally and internationally for its work and is one of the leading research groups in Europe. Over 100 scientific papers have been published and the team holds a number of patents in the area of biological process monitoring. Much of the work of SERC is in association with industry.
Download a pdf leaflet (64kb) describing some of the work.
The AD Centre has been established to provide two broad roles:
By undertaking these roles, the AD Centre will assist in the rapid deployment of anaerobic digestion across Wales and help to ensure that plants operating within Wales are technically robust and efficiently operated providing maximum benefits to operators and the Welsh society.


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There aren't any trains anymore. Not really. Sure, sometimes you have to stop and wait for a diesel engine pulling a long line of box cars to go by at the railroad crossing, but it's not the same.
I used to dream about trains. Not when I was asleep, but sharp vivid day dreams where the age of steam came alive again. All of that was before my time of course. I can't tell you what it might have felt like to ride in a red caboose, to watch the line of passenger cars snaking out in front of you, with the engine at the front billowing its smokey sooty prayers up into the sky. But sometimes if I close my eyes I can go back to that time, if only in my imagination.
I've heard of men born ahead of their time, but sometimes I feel like I was born past mine. I walk past clocks and check to see if they are driven by gears and springs or if they tick at the behest of cold and impeccably accurate quartz. My gaze lingers on battered old Victrola's in the antique shop, and I imagine sitting down with my family and listening to the music, warm and scratchy like a checked flannel shirt. But all I can do is imagine.
Because I'm trapped here in the digital age, an age of wonders that the men who built the world of gears and steam and the unholy crackle of electricity could never have dared to hope for. I am not foolish enough to believe that the world was perfect then, but I am perhaps wise enough to understand that it is not perfect now.
And yet here I sit, collecting stolen memories of that time so close and yet so far away, dreaming of a boy dreaming of me, aching to see the silver-spired future.


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I was super excited when I got my Samsung S3 Android device. However, one thing I was not excited about was finding a case for it. It's important to protect your cellphone, and finding a case that was trendy, easy to use, clean and one that would protect my phone was no easy task. That's when I turned to The Snugg: Tablet and Smartphone Cases and Covers that rock!
The Snugg offers amazing cases for tablets and smartphone and at reasonable prices, especially compared to other shops that ask more than double the price The Snugg does. The Snugg also do not cheap out on materials used to create their covers and cases, which is a huge plus with me – being a geek girl who loves anything gadget friendly.The Snugg Tan Pouch Case for the S3
The Snugg sent me a Tan Pouch Case for the Samsung Galaxy S3, and let me tell you that it is so gorgeous. I've gotten tons of compliments on it since using it, and I love the look and feel of tan suade.Easy to use pull strap to release your phone
The Snugg Tan Pouch is easy to use. My S3 fits inside it nice and snugg (no pun intended) and there is a strap at the back you just tug on to pop the phone out when you need it. It also makes it so your phone won't fall out of its case, which is the trouble I find with many other cases on the market for cell phones.
Tip: I tried The Snugg case for the S3 on my HTC Sense and it fit perfectly so the cases are universal and can be used with other Android smartphones similar to the Galaxy phones that are not listed on the website.
Buy it!
You can purchase The Snugg Tan Pouch Case for the S3 at their website http://www.thesnugg.com/ca for $24.99 CDN which is a fantastic price. Orders over $50 get free shipping! You can also purchase at Amazon.com.
Disclosure: I received product(s) for the purpose of this review. All opinions are 100% my own and come from my own testing of the product. Please refer to my blog disclosure policy for more information. Thanks for reading.


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A favorite green from our garden right now - the emerging lady's mantle leaves. Just fuzzy enough to catch dewdrops and rain.
These are the blocks I have so far - a seasonal gradation.
I finished the binding on the first color journal quilt this weekend and it has been through the wash. I will try and photograph it a bit better at some point. I was thinking as I looked at the April blocks I just made that the green and purple color combinations are a favorite, on the first quilt and also the new blocks. Noting that here to remember.


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Luther (WS)
Author: Teleart Berlin
Publisher: MGM
Format: DVD Movie
Categories: Biography/Autobiography, History, Movies & Music
Item: 0792861914
On Hand: 2
List Price:
Your Price:
$11.98 (20% off)
Secure Online Ordering
Armed with no more than faith and his quick wit, one man confronts the great powers of his day. Martin Luther's bold actions bring about an era of personal and religious freedoms unprecedented in history.
Spiritual conviction and radical politics define LUTHER, an historical biography which traces the life and career of Martin Luther (played convincingly by Joseph Fiennes), an inspired monk whose writings initiated the Protestant movement in 16th-century Germany. The film follows Luther's induction as a monk, his professorship in Wittenberg, where he eventually authors the 95 Theses, and continues through his struggles to reconcile his desire for sanctification with his increasing abhorrence of the corruption and hypocrisy pervading the Church's hierarchy. He is ultimately charged with heresy and must confront the ruling cardinals and princes, urging them to make the Scriptures available to the common believer. Reacting against Roman-Catholic strategies of bartering salvation for coinage, as well as the institution's hierarchies of religious knowledge and power, Luther throws the proverbial wrench in the system with his seditious writings.
Rated PG 13, Region 1 DVD, two hours, wide screen, filmed in Germany and Italy, English and Spanish Subtitles
|120 min
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Product Overview
Chinese Lieder
1 My Sentiment to the Yangtze River
2 Homeland Nostalgia
3 How Can I Not Miss Her
4 The Moon Reflection
5 Emei Mountain Air
6 Tristesse at the Yangguan Pass (Tunes of Guqin)
7 In the Silvery Moonlight (Tatar folk song)
8 The Sorrowful Shepherdess
9 Mama in the Candlelight
10 Gaolitai (Xinjiang folk song)
11 A Lovely Rose (Kazak folk song)
12 Swallow (Kazak folk song)
13 Mayeela (Kazak folk song)
14 The Running Stream (Yunnan folk song)
15 Mongolian Madrigal
16 Grassland Serenade
17 Mama in the Candlelight
18 Mayeela (Kazak folk song)
19.00 Homeland Nostalgia
20 Gaolitai (Xinjiang folk song)
Jingma Fan
The songs on this album include some of the most beloved classical poems from the Tang and Song dynasties (618 A.D.-1279 A.D.) as well as the most popular folk songs, which, because of their beauty and popularity in China, are today considered to be of highly artistic quality.
"As an opera singer born in China, I have enjoyed a 15-year-long career singing abroad. During this long period, I have experienced the highs and lows of traveling, singing, and simply surviving. Much of time I was on my own and was sometimes very lonely. Often I was overcome with acute nostalgia for the beautiful Chinese melodies that I remember from my childhood. I thought many times how much I would love to present them to the West. As a full-time singer performing in Western operas in Europe and North America, I had little opportunity to work on sharing my native music with the world. But now that, between concerts, I am often back in China, I have had time to properly prepare this great music, to sift through songs and make good selections. For the benefit of non-Chinese speakers, I have personally translated the lyrics of these songs into the English that can be sung. Additionally, there are four more songs sung in English included as bonus tracks; I believe it is the first time these songs have ever been recorded." Jingma Fan


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Please make sure you've updated to the latest graphic card drivers (NVIDIA 398.36, AMD 18.6.1 at this writing). If you think you have updated, try to stop the Oculus Runtime service, uninstall and reinstall your GFX drivers, and then start the service once more.
Please delete your entire Preferences folder in My Documents/ Medium and restart Medium.
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Make sure your HMD is plugged into your GPU.
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If you read enough Hollywood columns and watch enough television, you are bound to get all sorts of advice about dating and relationships. If you look at the the track records of many Hollywood types, you may want to ignore much of what they have to say. However, at times they do have some wisdom to share.
In a recent New York Post article, titled You're stupid for having sex on the first date, Dr Ruth (Westheimer) went on about how sex on the first date is is a "no-no." This advice is not likely heeded by many of today's young people. There is much pressure out there for young boys and girls to have sex if they want to be cool, popular, and dating. This is rather sad, because they don't realize the shallow nature of such relationships and they don't understand how many fruitless people they will sleep with leading to nothing meaningful a.k.a. a relationship. They are also rather clueless about the health risks they get exposed to in sleeping around.
Older daters from past generations have an entirely different take on sex and dating. They were generally brought up to place sex on a pedestal reserved for someone special. This is not to say that the hippie generation didn't engage in lots of sex. They after all coined the term "free love." However, after many years of leading more normal lives, they have learned that wanton sex is not the answer. Of course what is the question? The question is do you want a meaningful relationship? If so, sex on the first date is not likely to achieve that goal.
The next star powered advice comes from James Brolin, in a Page Six article, where he offers his number one marriage tip: Keep your finances separate. He married Barbara Streisand twenty years ago and they are still going strong. There's much merit to his advice. One of the biggest strains on relationships has to do with money. If you are bound by money, there is always that concern or worry about what happens when, and if, you breakup? His advice makes a lot of sense for second marriages, or, as in his case, third marriages.
For most people starting out in a marriage, they almost always commingle their money. To not do this in a first marriage would be rather unconventional. Having separate accounts only works in a first marriage if both parties have a ton of money. If you are not loaded, and getting married for the first time, and your mate wants to keep money separate, you may have a problem. Not that it can't work, but traditionally, one person is the bread winner while the other is the home care person. In those situations, you need to both have a financial interest in the relationship. If both have equal paying jobs and they decided to segregate incomes and share in expenses, it would make divorce much easier, but as noted, this is not the norm and tends to breed hostility and trust issues become ever present.
Well that's it for rich and famous dating and relationship advice. As more comes down the pike you will be alerted accordingly. For more dating and relationship advice go to: http://www.whoyoudating.com and read the blog.


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Get quotes fast. Use our booking enquiry form to check availability and costs.
Tailor-made parties to suit the birthday child/event. Many themes available or request your own themed party.Run by professional performer (clown, dancer, storyteller) and dance and drama teacher Carrie McCarthy.Interactive parties including activities such as stories, games, puppets, songs, music, dance, mime, drama, face-painting, circus skills, magic, crafts, dressing-up.Themes incude; Dance parties; ballet, disco dance, Spanish Flamenco, Egyptian belly dance.Educational parties; Ancient Egyptian, Native American, Historical.Kids favourites; Pricesses and Knights, Pirates and Mermaids, Clowns/Circus, Animals, Wizards. Fairies, Aliens, Bugs n Butterflies, Teddy Bear's Picnic, Traditional parties.Seasonal; Halloween, Xmas, Easter etc.Live animal parties; Carrie can bring some very cute pets who enjoy being handled to see the children. Age 7 and up only and allergy checks advised in advance.Games and other activities included in this option.Outdoor events such as Galas and festivals catered for.Walkabouts in many and various guises available. Please request full details.Carrie has extensive experience of special needs and caters for clients with additional needs.She is a member of Equity Actors' Union.Environmentally friendly entertainment.Only serious enquiries please and Carrie works on a professional basis only (no freebies)
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ere: Originalhomepage Hotel Alpenrose Ischgl with onlineshop for reservations, hotel reviews, very old house directly by skipist/lift/center, email@example.com
Welcome in the Alpenrose: To live up to the name Alpenrose, several blossoms of equal value, with you together, build a nice slowly growing highmountain flower. Our goal/ideal is: to live simply/healthy, to respect all natural grown/history/old and to keep and conserve the proven. That is not always easy nowadays, also not always easy for our guests.
We are a traditional, family run hotel, in excellent location, with personal face-to-face service. Our house is very old. Therefore we have only 2 stars. But in exchange, our house is cosy and has atmosphere. A grade up for our hotel is the excellent location, in the center of Ischgl, right next to Pardatschgrat-cablecar and the ski pist (only 50 seconds to walk). Best food material and a high cleaningstandart is characteristic for us. In the mornings you get a lavish breakfast buffet that will leave you prepared for a great day, and in the evenings you get, if you wish, a hearty and tasty dinner. Sat-TV and pay-WLAN/pay-WIFI is everywhere. We have long texts. But the most important is standing at the beginning.
Our hotel is one of the few, over decades, naturally grown hotels. And so, everything is well functional. A big part of our furniture is from the 1970ies. Some bathrooms from the 60ies, not all, are small. For those, who do not like "very old equipment", it is better not to reservate, please. Those, who can respect things, which are old and experienced growth over decades, will feel good in our hotel.
Wellness and indoor pool with public mixed sauna, massage etc. you find in the Silvrettacenter, which is only 4 minutes walk away from Alpenrose.
Up here, by clicking "free rooms/prices/onlinereservation" you can also do an online-reservation, like with an onlineshop, and(!) at the same time, a certified, secure, 40%-100% of endsum online-payment of your holidaytimeproduct. You get then online, automatically and prompt, an online-reservation-confirmation. Our top-service for you.
Ischgl has a high price level. Our prices have to be seen, please, in relation to the high prices in Ischgl, to get a real imagination of what is fact.
Our comments to reviews, tests, evaluations, travel records, of everywhere in the internet, of some guests who stayed in our hotel, you see up here under the rigister: "request/reviews".
The austrian AGBH an our General Terms and Conditions (T&C, AGB) are valid. For details, please click below in the footer. They also contain a stable value clause for the hotel.


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Under Construction! Pre-sale are now available!! Amazing Morgan "E" Plan. Master and Guest Bedrooms are located on the main level. Gorgeous Level Lot. This home features 42" cabinets, dining area, open floor plan. Oversized master suite with his/her closet and tiled shower. Upstairs is perfect for your teens to have their own space. Two spacious bedrooms with a full bath. This home offfers laundry on the main, 2-car garage and a cozy community nestled in the Alexander High School District. Only a few homes to be built in this community. Large Lots. Pick your Lot, Pick your Plan, Make your Selections!
2 Car, Attached, Garage, Kitchen Level Entry, Side/Rear Entrance
Ceilings - Trey, Foyer - Entrance, Walk-in Closet
Dishwasher, Icemaker Line, Microwave - Built In, Range/Oven, Stainless Steel Appliance
Heat Pump, Zoned/Dual, Electric
Electric, Heat Pump, Zoned/Dual
130x263x150x243, Corner, Level Lot, 1/2 - 1 Acre
|Price Increased (from $359,900)
|$10,000 (2.78%)
|Active (from New)
The data relating to real estate for sale on this web site comes in part from the Broker Reciprocity Program of Georgia MLS. Real estate listings held by brokerage firms other than Keller Williams Intown are marked with the Broker Reciprocity logo and detailed information about them includes the name of the listing brokers.
The information being provided is for consumers' personal, non-commercial use and may not be used for any purpose other than to identify prospective properties consumers may be interested in purchasing. Information Deemed Reliable But Not Guaranteed.
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Copyright 2020 Georgia MLS. All rights reserved.
Listing information last updated on June 2nd, 2020 at 6:32am EDT.


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Alta Motors, an electric bike manufacturing company based out of San Francisco, has just expanded its product lineup by launching a new Enduro model called the Redshift EX. This is based on the company's other motocross-focused product, the Redshift MX.
Not much new is there to see in the Redshift EX. Alta Motors basically took the Redshift MX, made some changes in its chassis and added a licence plate to make it road-legal. There you go, a brand new motorcycle.
We will also get to see an 18" inch rear wheel, narrower rake angle and a larger offset on the new Redshift EX. To make things more interesting, Alta Motors also added a WP rear suspension setup with a custom reservoir, a small rear brake and wrapped around the wheels Bridgestone Battlecross X30 tyres.
Alta Motors claims that the Redshift EX weighs about 125kg, which is quite normal for an electric bike and has a 5.8 kWh battery pack. It produces a max power of 40hp and generates a peak torque of approx 162Nm. The entire pack would need around 2.5 hrs to fully charge on a 240V input connection. Alta claims that the EX would last around 4 hrs in off-road conditions with a full charge. Of course, this time will vary based on the riding terrain and techniques, but you do get the hang of it, right?
Since electric motors generally deliver power instantly, it'd be interesting to see how Alta Motors has managed to control it because you need to have the right amount of power and torque at the right time in off-road conditions, otherwise things can turn up pretty bad.
Alta Motors is moving up the vertical ladder of electric vehicles quite quickly and has increased its range of products to attract an audience from different genres and age. Good work, there. The next product that we'd see the company coming out with would be a street-tracker model.


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A title at the Globus Magazine cover, May 18, 2018, said "Is Martina Dalić down due to Russian hackers!?" That statement, although with question mark, implied that index.hr is actually an instrument of Russian hackers, in other words of Russian interests. And Globus is the magazine that disclosed Lex Agrokor writers and their suspect able business arrangements in the process of re-structuring Agrokor corporation. The implication was not argumented or proved and article that was the base for the title was full of speculations. Index journalist Ilko Ćimić, who disclosed secret electronic communication, was not contacted at any point.
We want to remind the readers that index.hr portal has been more systematic in investigating Lex Agrokor background, its potential writers and lucrative business arrangements since spring 2017 then other mainstream media. Publication of secret e-mail correspondence between ex-vice president Martina Dalić tops that investigation of index journalists.
It is legitimate to put questions about ways e-mails of ex vice-president became public, but it has to be based on relevant information, not just speculations with clear goal of distracting major topic – what is going on with Lex Agrokor. The most important media task is to reveal information of public interest and not to distract it by defaming media that has published information about Agrokor case or is about to do so.
Denis Romac, CJA vice-president for the CJA Executive Board


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Lewy bodies (LB) are protein inclusions containing disaggregated oligomers of many cellular proteins. The German neurologist named Friederich Lewy[1] was the first physician-scientist to describe the abnormal protein deposits in 1912 in people with paralysis agitans and, later on, Parkinson disease. Dystrophic neurites (LNs) are precursors of LB and they can contain deposits of ubiquitin (Ub) and alpha-synuclein (a-Syn), formally becoming LB and accumulating in synaptic terminals and axonal processes. A-Syn, encoded by SNCA, is a protein found in presynaptic terminals and thought to have an important neurotransmission communication between neurons and neurotransmitter vesicle trafficking.[2][3][4] Ubiquitin is a protein involved in changing proteins biochemically to target them to degradation and autophagy.[5] The Ub is usually at the core and neurofilaments at the outermost layer. Per recent animal model studies, a mutated form of a-Syn (A30P) leads to disaggregation, transcriptional deregulation and silencing of DNA; it also leads to the disruption of Golgi and endoplasmic reticulum, and finally it may also play a role in collagen gene transcription, a basement membrane protein that maintains the integrity of dopaminergic neurons. These cellular processes go awry in dementia with Lewy bodies (DLB) and Parkinson disease (PD).[6] These aberrant oligomers are also present in many other neurodegenerative disorders including, Alzheimer disease (AD), striatonigral degeneration, olivopontocerebellar atrophy, and pantothenate kinase-associated neurodegeneration (Hallervorden Spatz disease), but it is unknown if they share the same pathogenesis. This article focuses on DLB and PD dementia as they are the most common forms of dementia besides Alzheimer disease. The worldwide incidence of DLB is about 1% to 2% (approximately 3 to 4 per 100,000 person-years) on patients older than 65 years and about 5% of all dementia cases in those over the age of 75.[7][8] For PD dementia, approximately 10% of a PD population will develop dementia annually with an overall prevalence of 31.1% in patients between 65 to 90 years old. The data concerning age at disease or dementia onset are highly variable in the literature.
The disaggregation of alpha-synuclein, Ub, and LN are a pathognomonic neuropathological finding on autopsy in patients with PD, and DLB, found in many regions within the central nervous system including the cerebral cortex, limbic cortex, substantia nigra, hippocampus. Structurally, they are single, multiple or polymorphic. It characterizes them into two major groups: classical or cortical LB. The classifications are based on morphology, cellular components, and location within the brain. Although Lewy Bodies are implicated in many of these disorders, it is debatable whether they are a consequence of cellular damage and dysfunction within the neuro integrity or a cause of itself of the clinicopathological symptoms seen patients. This article briefly covers the different anatomical, clinical and biochemical pathologies involved with Lewy body formation. The goal is not to provide an exhaustive description of LBs, rather a snapshot that can be useful for the everyday clinician interested in the topic.
Based on a semi-quantitative assessment of LBs in a large autopsy series, the Braak staging was proposed in 2003[9][10] to characterize LB pathology lesion progression in the brain. It attempts to centralize and provide a systematic framework of the progression of the disorder using neuroanatomy LB lesion density and progressive dissemination starting from the brainstem and ending in the neocortex. Per this categorization, the lesions begin in the lower brainstem and involve the intermediate reticular zone, anterior olfactory nucleus, and nucleus basalis membrane (NBM), with midbrain regions being preserved (stage 1). It continues progressing into the caudal raphe nuclei, gigantocellular reticular nucleus, and coeruleus-subcoeruleus complex (stage 2). Professionals consider these stages asymptomatic or pre-symptomatic and may explain early non-motor (autonomic and olfactory) symptoms that characterize disorders such as PD and DLB, preceding much of the motor and sensory dysfunctions. During stage 3, the inclusions will stain in the locus coeruleus (LC), amygdala, nuclei of the basal forebrain, and posterolateral and posteromedial substantia nigra compacta (SNc), with relative preservation of the cortex. Finally, we can characterize Stage 4 by the further damage to the amygdala, temporal limbic, and neocortex; it correlates these with symptomatic stages of a disease like PD. Once the abnormal protein inclusions reach stages 5 and 6, it is spread through the cortex with devastating effects on complex sensory association cortex regions and prefrontal and temporal areas (e.g., hippocampus) involved in executive brain functions, and learning and memory. Different neurotransmitters subtypes compose the anatomical structures and a neuron-to-neuron network of communication (e.g. norepinephrine, acetylcholine, serotonin, among others) according to regional specific brain structures affected, adding complexity to the possible variable clinical syndromes that characterize neurodegenerative disorders such as PD and DLB.
Some scholars and scientists are skeptical that the Braak staging system can accurately correlate neuroanatomical LB density/dissemination with predictable clinical symptoms. The staging is based on retrospective clinical pathologic studies in younger-onset PD patients with about 6% to 40% of the cases not following the proposed caudo-rostral progression pattern of pathology.[11] For example, there was sparing of medullary nuclei in 7% to 8.3% of clinically manifested PD cases with alpha-synuclein inclusions in midbrain and cortex corresponding to Braak stages 4 and 5, whereas mild parkinsonian symptoms were already observed in stages 2 and 3. Additionally, mixed pathologies with variable Alzheimer-type and DLB pathology can further complicate the precision of the Braak stages. Unfortunately, there is no clear relationship between Braak LB stage and the clinical severity of PD, retrospective autopsy series in 30% to 55% of elderly subjects with widespread Lewy-related pathology (Braak stages 5 and 6) reported no definite neuropsychiatric symptoms, suggesting considerable cerebral compensatory mechanisms. Almost half of the LB-positive cases during the Braak based studies were not classifiable. The etiology of these deviations from the current staging schemes of alpha-synuclein pathology in PD and DLB, its relation to the onset of classical parkinsonian symptoms and lack of definite clinical deficits despite widespread alpha-synuclein pathology required a better classification system.[12]
Beach and colleagues (2009)[13] created a modified criterion that correlates nigrostriatal degeneration, cognitive impairment, and motor dysfunction with many Lewy Body associated disorders. This classification was more specific by combining anatomical inclusion findings with biochemical enzymatic activity of TH, an enzyme upstream of L-dopa production and a precursor of dopamine production in the brain. It contains the following anatomical pathology staging: I, olfactory bulb only; IIa, brainstem predominant; IIb, limbic predominant; III, brainstem and limbic; and IV, neocortical. This study established a multi-factorial correlation between the deterioration of striatal TH concentration, Mini-Mental State Examination score, and Unified Parkinson's Disease Rating Scale part III. The authors found significant correlations between these measures and LB-a-Syn pathology.
The above-mentioned complexity is exemplified in patients with incidental Lewy body disease (ILBD), or LBs found in autopsy with no documented clinical parkinsonism.[14][15] The distribution of LBs in ILBD is similar to the PD, but the lesions spare the limbic cortex with, on average, lower Braak scores, compared to diagnosed PD cases. In the latter, LBs are found in most brain regions with significantly higher Braak PD stage. Additionally, decreased TH immunoreactivity was shown in the striatum and epicardial nerve fibers of ILBD, but to a lesser extent than PD.[15][16] However, in about 5% to 20% of asymptomatic patients on autopsy have shown abundant Lewy pathology with a distribution pattern similar to that seen in PD, with substantia nigra relatively well preserved. This challenges the classical Braak brainstem to cortex distribution and suggests more of a multiregional disease progression from the onset. There are prevalent outlying cases that do not conform to any staging scheme, with varying distributions of LBs in patients likely greater than expected for PD but may also reflect the different cohorts examined, different technical issues or incidental Lewy body disease rather than overt PD. Ultimately, the Beach modified staging showed a promising correlation between anatomical pathology findings, biochemical markers, and clinical ancillary testing; however, it requires validation at a larger scale.
The biochemical pathways involved in the formation of LB, specifically alpha-synuclein, are associated with protein misaggregation and impaired protein cleavage. [17] Wild type alpha-synuclein is prone to form oligomeric and prefibrillar structures that alter lysosomal trafficking and mitochondrial function. Specifically, in the mitochondria, early soluble oligomeric forms of a-Syn interfere with complex I in the electron transport chain, generating reactive oxygen species. This can disrupt high energy production for functional neurotransmitter communication between dopaminergic neurons in the brain. Some scientists consider LBs to be markers of ongoing neuronal damage, other as a sequela of harmless end products of sequestration of toxic molecules that may or may not be directly involved in apoptosis or cell death. There is an inverse correlation between cell viability and the amount of a-Syn aggregates in the cells. Future studies will determine whether LBs inclusions are upstream or downstream of apoptosis or cell death.
Classical and cortical LBs share immunochemical and biochemical characteristics. The major biochemical components include a-Syn, ubiquitin (Ub), and phosphorylated Ub associated with multiple other substances, including structural fibrillary elements, a-Syn-binding proteins, proteins implicated in the Ub-proteasome system, synphilin-1, aggresome- and mitochondria-related proteins, and cytoskeletal, cytosolic, and cellular response proteins, among others.
LBs have a distinct central Parkin-positive and Ub-positive domain with a-Syn in the periphery. Aggregation of a-Syn, synphilin, and Parkin within LBs suggests that parkin plays a role in ubiquitination and modification of a-Syn. Tyrosine hydrolase (TH) and choline-acetyl transferase (ChAT) are co-localized in cortical LBs; brainstem LBs have TH and ChAT immunoreactivity in the core, surrounded by a peripheral rim of a-Syn, suggesting that they may disrupt cholinergic and catecholaminergic transmitter production.[18] LBs and pale bodies are immunoreactive for autophagic proteins p62 and NBR1 which may sequester the soluble oligomeric a-Syn into inclusions.[19][20] They further contain 14-3-3 proteins that are involved in signal transduction pathways and interact with a-Syn and torsin A, a protein that may serve as a chaperone for misfolded proteins that require degradation.[21] A-Syn aggregates in LBs are refractory to clearance and may contribute to increased death of aggregate-bearing cells. Proteomic analysis of cortical LBs has revealed 200+ metabolites and proteins related to multiple or unknown functions.[22] In substantia nigra proteomic study, they identified 204 proteins displayed significant expression level changes in PD patients versus controls, implicated in pathogenic processes including mitochondrial dysfunction, oxidative stress, or cytoskeleton impairment.[23]
In summary, the Ub-proteasome system and the autophagy pathway help our brain clear toxic forms of misaggregated proteins, including helping with a-Syn turnover. Dysfunctional proteolytic pathways may result in accumulation of toxic forms of a-Syn. Ubiquitinated proteins in LBs may be a manifestation of attempts by the cellular machinery to eliminate damaged cellular components and delay the onset of neuronal degeneration. Some evidence showing this is the high incidence of mitochondrial DNA deletion in LB-positive neurons in PD brain compared to LB-negative neurons and controls, suggesting increased mitochondrial damage in LB-positive neurons.[24][25] These deletions trigger neuroprotective mechanisms that at one point may become overwhelmed. However, how this process works in the mitochondria, specifically how soluble convert to insoluble aggregates in neurons is poorly understood and requires further research.
The classical LB are spherical hyaline eosinophilic cytoplasmic inclusions (8 to 30 micrometer-diameter) comprising concentric lamellar bands surrounded by a pale-stained halo of 10 nm of wide radiating fibrils. Cortical LBs are difficult to find under the microscope, chemically eosinophilic, rounded, angular, without a halo. Additionally, cortical LBs are disorganized, granulofibrillary structures composed of 10- to 27-nm wide filaments, without a central core. They concentrate in lower cortical layers, with recorded accumulation in the hippocampus, insular cortex, amygdala and sometimes cingulate gyrus. Similar lesions, rounded areas of granular, pale-staining eosinophilic material displacing neuromelanin (NM) in brainstem neurons are precursors of LBs. As described, the alpha-synuclein is the best marker to detect LBs. Antibodies that recognize N-terminal epitopes (synucleins 505, 506, and 514) selectively detect a-Syn.[26]
The etiology and pathogenesis of synucleinopathies are complex with proposed interactions between gene transcription and expression and environmental insults that lead to cellular dysfunction in vulnerable neurons in the central nervous system. Dysfunctional regulation, processing, cleavage and degradation of abnormal cytoskeletal and endovesical (Golgi and endovascular reticulum) proteins within the cells are thought to interfere with mitochondrial dynamics, membrane integrity, proteosome, and lysosomal pathways. Genetic susceptibility may determine susceptibility, for example, free radicals generated through disruption of complex I activity, increasing the nuclear or mitochondrial genomic deficit. Environmental interactions factors such as metabolism of exogenous drugs can generate endogenous neurotoxins that can also trigger the generation of reactive oxygen species that disrupt calcium homeostasis and trigger cell death. Neuronal pathways are susceptible to oxidative processes, and therefore, become a prime target to these insults. Specifically, reactive oxygen species can trigger excitotoxicity by increasing glutamate in the synapses, triggering neuroinflammatory microglial processes and most likely, a combination of all these complex processes. Interestingly, Lewy bodies are like other aggregated proteins such as neurofibrillary tangles (NFT) in AD and/or Pick bodies in terms of being present as markers of neurodegenerative processes. What exact analogous mechanism they have in common to disturb cellular activity is complex and is currently under investigation.[27][28][29][30]
This section focuses on describing the clinical symptoms and pathophysiological findings that distinguish DLB with PD dementia, as those are the most common diseases associated with Lewy body deposition. The section also notes promising biomarkers for early diagnosis of DLB or PD. DLB is the second most common type of progressive dementia after Alzheimer disease dementia. DLB predominantly shows greater cognitive, psychiatric, and autonomic deficits than PD, which includes severe and rapid fluctuations in verbal memory, frontal executive function deficits, attention, spontaneous visual hallucinations, delusions, orthostatic hypotension, prominent falls/gait disturbances, and more rapidly progressive cognitive decline compared to motor symptoms. Similarities with PD include the development of motor symptoms including rigidity, akinesia, mood disturbances, REM sleep behavior disorder, language, and visuospatial and constructive deficits, and cognitive impairment (develops later in PD patients). Resting tremors are more common with Parkinson disease than DLB. The typical rigidity, tremors, akinesia and postural instability precede the cognitive deficits in PD dementia.
PET and postmortem studies have revealed more pronounced cortical atrophy, elevated cortical and limbic Lewy body pathologies, higher Abeta and tau loads in cortex and striatum in DLB compared to PD dementia. Specifically, gray matter cortical atrophy more frequent and more severe in DLB. White matter hyperintensities in temporal lobe are more severe and more frequent in DLB. There is also a difference in functional connectivity and corticostriatal disruption with PD dementia being characterized by frontal cortical disruption and DLB with more parietal and occipital disruption. Additionally, amyloid and tau signal seems to be more prevalent in DLB on PET imaging and CSF profiles. Functional differences in advanced nuclear imaging are seen in DLB compared to PD dementia with decreased DAT binding in the caudate related to functional impairment. Cerebrospinal fluid (CSF) alpha-synuclein oligomers are increased in PD dementia in comparison to DLB. Overall, PET studies have failed to show any differences in cortical and striatal cholinergic and dopaminergic deficits.
Clinical management of both DLB and PD dementia includes cholinesterase inhibitors like rivastigmine. Atypical antipsychotic agents like quetiapine may improve psychosis in PDD/DLB, but the evidence for this is poor and adverse effects from such therapy are common and may be severe. Non-pharmacological interventions can also be effective but require further study. Currently, no disease-modifying therapies are available, although current efforts are on the way to find diagnostic markers that could identify these diseases sooner in hopes to start treatment sooner and prolong the disease progression. Many biomarkers including CSF oligomeric A-syn, DJ-1, lysosomal enzymes (e.g., glucocerebrosidase) show promise as a diagnostic biomarker of PD, but require standardization of available assay, homogenous protocols, and surpass other methodological challenges to reach a large scale validation that can be reliable for clinical use.[31][32][33][34][35]
Although Lewy body pathologies are intriguing and may provide a clue of the pathophysiology of DLB, PD dementia, and other related neurodegenerative disorders, it is discovered on autopsy and therefore not useful for routine clinical diagnosis. DLB and PD are important dementia syndromes that overlap in many clinical features, genetics, neuropathology, and management. They are considered subtypes of an alpha-synuclein-associated disease spectrum (Lewy body diseases), from the incidental Lewy body disease and non-demented Parkinson disease to PDD, DLB, and DLB with Alzheimer disease at the most severe end. The clinical symptoms in relation to the different cognitive, psychiatric and motor domains should be sufficient for the diagnosis. A rigorous history and physical exam, with ancillary testing including imaging and nuclear studies that like DAT, CSF profiles and tau and amyloid pathology can be useful for diagnostic purposes but does not change medical management of these disorders. The interesting phenomenon of various biochemical markers that accumulate in DLB and PD dementia including alpha-synuclein, ubiquitin, tau, and amyloid provides evidence of the multi-factorial and complex processes that become dysfunctional in a chronic and progressive neurodegenerative disease such as DLB and PD dementia. The pathophysiological threshold to develop clinical symptoms when these cellular and biochemical processes are disrupted is elusive. Although this anatomical neuropathological classification above mentioned is useful, it does not entirely predict the diagnosis, progression, and prognosis in all the synucleopathies. Further research is needed to develop relevant biomarkers and therapeutic targets that can delay the progression of diseases such as DLB and PD.
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|Dölle C,Flønes I,Nido GS,Miletic H,Osuagwu N,Kristoffersen S,Lilleng PK,Larsen JP,Tysnes OB,Haugarvoll K,Bindoff LA,Tzoulis C, Defective mitochondrial DNA homeostasis in the substantia nigra in Parkinson disease. Nature communications. 2016 Nov 22 [PubMed PMID: 27874000]
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LinkedIn is launching a tinder-like swipe feature which would allow users choose a mentor on the site. The feature which is currently available to a group of handpicked mentors in San Francisco and Australia lets you "hook up" with a mentor online for whatever reason you may need them for.
The Microsoft owned service will allow you mentor people who may be passing through the same system as you and an example would be a graduate of a school mentoring some students in the same institution.
By allowing users discover mentors in fields they are interested in, LinkedIn hopes to build on its career oriented service which allows you discover jobs and recruiters in your area easily.
LinkedIn has implemented a series of services since its acquisition by Microsoft acquired the largest professional network in the world last year for $26b. From a revamped website to helping you discover how much people doing similar things as you are earning, LinkedIn wants to be your go to place for nearly everything professional.
That said, it's quite amazing the number of services that have decided to adopt the original Tinder swipe signature feature and now it's LinkedIn that's using the style. On Tinder, the feature helps you easily discover potential dates by allowing you swipe and with each picture that appears on your screen, you can choose to like or dislike. This information is sent to the users one has shown interest in and if they choose to get back to you, fine.
By adopting such a model on LinkedIn, you can now play the hook up game only this time it's professional.


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The National Screening Room Is Open
The Library of Congress (LoC) has introduced the National Screening Room, a free collection of over a century's worth of video assets that capture "a broad range of American life." The videos include "digitized historical films, commercials, newsreels and other clips… Most of the movies are in the public domain and are available for download; others are only available to stream."
- Access the National Screening Room [^web]


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Free e-samples of prescription drugs offer little value to consumers
According to a new study, free prescription drug samples found on the internet offer little value to consumers. Though the urge to try free or discounted e-samples offered by pharmaceutical companies may be compelling, you'll pay a higher cost to continue the drug. In most cases a less expensive generic equivalent is not available, and the cost of continuing the high.
The findings suggest that free e-samples of prescription drugs do not serve the public. The findings are published in the Archives of Internal Medicine from a study led by Dr. William G. Weppner of the University of Washington (UW) Department of Medicine and the Veterans Affairs Medical Center in Boise, Idaho.
The findings also showed that e-samples and discounted prescription drugs are emphasized rather than information about side effects and drug effectiveness. Information about the prescription tends to be generalized, when provided directly to consumers over the internet. The US and New Zealand are the only countries that allow drug marketing directly to consumers.
Relative to health care reform, Dr. Weppner says, "Many of these discounts are aimed at co-pays, which could increase costs to consumers via health insurance premiums." More than half of the most popularly prescribed drugs offer discounts directly to consumers via the Internet, noted in the study.
Prescription drugs offered for free or at a discount to consumers on the Internet only amount to a five percent savings yearly for consumers, are expensive to continue, have no generic equivalent, and are often still under patent protection.
In order to get free e-samples of prescription drugs, consumers are required to submit e-mail address, medical information, and postal address.
The authors say, "Collection of such information may compromise patient privacy if made accessible to unauthorized users. An interesting feature of this marketing strategy is its potential role as a means in which Web users are coerced to provide consumer information that unwittingly drives the content of the Web sites they view. Such a new version of targeted direct-to-consumer advertising could automatically gather information from drug-offer forms, patient searches, previously visited Web sites or even text from e-mail. The strategy would then provide advertising links to Web pages offering discounted or free coupons for drugs."
The true value of free e-samples is minimal according to the authors, though the marketing strategy is common.
The FDA is evaluating implementation of new guidelines for direct consumer marketing of prescription medications. If new practices are mandated, consumers would be better informed about the benefits, effect, and side effects of prescription medications, and free e-samples and drug discounts that offer no significant benefit to consumers would become a thing of the past.
Arch Intern Med. 2009;169(21):2024-2030


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- This event has passed.
Strange Brew – 26th of August
26th August 2017 @ 8:00 pm - 11:30 pm
Rock and blues covers band with a touch of soul. Rocking blues with a touch of soul! Strange Brew live guarantee a good time with good music. 'Oldies but goodies' covers, ranging from 60s classics to Santana and The Eagles, mixed with soul and rock and roll.


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Most people in the US will experience some form of low back pain once during their lifetime. It is one of the most common reasons why people go to the doctor or miss work.
Physical therapy can help prevent and lessen most back pain episodes and we will teach you proper body mechanics to keep you functional and moving.
McKenzie Method is an exercise-based approach to assessment, diagnosis and treatment.
McKenzie allows patients to understand the principles of their disease/condition and allow the patient to manage their symptoms independently. Common conditions treated with this method are Neck Pain, Back Pain, Herniated Discs, Sciatica and Sacro-Iliac joint pain.


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From Zappa Wiki Jawaka
Revision as of 09:00, 12 July 2019 by PopFanDoug (Talk | contribs)
Several paintings have been attributed to Frank Zappa. They mostly date from his school days and teenage years.
One such piece was seen on History Detectives a television show about American History. In 2012, they examined a collage that a collector bought in a South Carolina thrift shop. The artwork was an image of a drum store. Struck by the piece and its "F.Z." signature, a collector, Edward Lewis, suspected that it might be the work of Frank Zappa.[1] History Detectives offered evidence that this was a Zappa piece, but could not definitively prove it. Nonetheless, they estimated the collage, for which Lewis paid $5, to be worth $25,000.[2]
- frank zappa - oddities.
- A rough compilation of some of FZ's paintings, drawings & collages that we know of, including some that we don't know for sure.


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Tara + Alicia
Read Their Love Story!
IT was love as first sight..we locked eyes back in 2006 ... And have been in love ever since ... we have had our ups and downs like any normal Couple.... But we have Always managed to put And keep us At one.... last year. October.23rd, 2014...I get down on one knee and proposed to the woman of my Dreams And she did me the honor of saying yes !!! And making me the most luckiest and blessed human being on this Earth to be Able to share this thing we Call life with the love of my life And MY Soon to be wife.
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Trucking industry blasts underspending on rest stops, fears it will take major accident to spark change
South Australia's trucking industry has slammed a lack of funding for vehicle rest stops, saying it could take up to 50 years before there are enough stops to meet the Government's own standards.
According to the SA Road Transport Association (SARTA), Federal Government requirements stipulate there must be an available rest station for truckies every 80 kilometres.
However, the association claims there are only 20 per cent of the number of rest stops needed to meet that requirement.
SARTA executive officer Steve Shearer said it would take decades to meet the requirement based on current funding levels.
"No government of any persuasion has ever spent enough money on rest areas for the trucking industry," he said.
"That's outrageous. If you said to the community that we will build you a new hospital but we are going to take 40 or 50 years to do it, that government would get kicked out at the next election.
"That is not enough [funding], and we think it is time that government at all levels take fatigue management in the trucking industry seriously."
Drivers need breaks to avoid fatigue
Last week, the Australian Trucking Association (ATA) revealed that the Federal Government expected to spend just over $46 million of its $60 million budget for funding truck rest areas and other productivity projects in the 2017-18 financial year.
ATA chief executive Ben Maguire said in a profession where drivers were required to take enough rest breaks, it was not good enough.
"The fatigue laws require truck drivers to take regular breaks, but there still aren't enough truck rest areas in the right places," he said.
"When rest areas are available, they are, all too often, filled up with caravans. Their condition can be shocking."
Decades of lobbying with little success
Mr Shearer said he had been lobbying governments for more than two decades for more rest stop funding, with little success.
Grimly, he forecast the only thing that may prompt a boost in finances was a significant road crash.
"Short of arming ourselves with pitchforks, and any other implements we get our hands on, and marching on parliament, you just don't get anywhere," he said.
"They do not see votes in it, so they do not do it.
Penalised for not having a rest
The industry has been putting a major focus on combatting driver fatigue, including developing smart technology to monitor a driver's heart rate.
According to the SARTA, drivers are required take a 15 or 30-minute break on a five or eight-hour shift respectively.
However, Mr Shearer said when faced with no rest areas, or when the rest areas were being utilised by caravans or road-building material, drivers could ultimately cop financial punishment.
"We are bound up in rules, red tape and fines, but governments are failing to provide the rest areas.
"It could be 100 or 200 kilometres up the road before we find another one."
Federal Infrastructure and Transport Minister Michael McCormack, and South Australian Transport, Infrastructure and Local Government Minister Stephan Knoll have been approached for comment.
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"I remained silent for 10 years concerning the behavior of the priesthood." -- Daisaku Ikeda
"I, Nichiren, am the only person who is aware of this. If I should begrudge my life and thus refrain from speaking out, not only would I be failing to repay the debt of gratitude I owe to my country, but I would also be acting as an enemy of Shakyamuni Buddha, the lord of teachings. On the other hand, I knew from the outset that, if I set aside my fears and declared things exactly as they are, I would be sentenced to death. And even if I should escape the death penalty, I would surely be condemned to exile. So great is the debt of gratitude I owe the Buddha, however, that I have not let others intimidate me, but have spoken out."


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Table_3_A Comparison of Co-methylation Relationships Between Rheumatoid Arthritis and Parkinson's Disease.XLSX
Rheumatoid arthritis (RA) is a complex autoimmune disease. Recent studies have identified the DNA methylation loci associated with RA and found that DNA methylation was a potential mediator of genetic risk. Parkinson's disease (PD) is a common neurodegenerative disease. Several studies have indicated that DNA methylation levels are linked to PD, and genes related to the immune system are significantly enriched in PD-related methylation modules. Although recent studies have provided profound insights into the DNA methylation of both RA and PD, no shared co-methylation relationships have been identified to date. Therefore, we sought to identify shared co-methylation relationships linked to RA and PD. Here, we calculated the Pearson's correlation coefficient (PCC) of 225,239,700 gene pairs and determined the differences and similarities between the two diseases. The global co-methylation change between in PD cases and controls was larger than that between RA cases and controls. We found 337 gene pairs with large changes that were shared between RA and PD. This co-methylation relationship study represents a new area of study for both RA and PD and provides new ideas for further study of the shared biological mechanisms of RA and PD.
- Radiology and Organ Imaging
- Decision Making
- Clinical Nursing: Tertiary (Rehabilitative)
- Image Processing
- Autonomic Nervous System
- Cellular Nervous System
- Biological Engineering
- Sensory Systems
- Central Nervous System
- Neuroscience
- Endocrinology
- Artificial Intelligence and Image Processing
- Signal Processing
- Rehabilitation Engineering
- Biomedical Engineering not elsewhere classified
- Stem Cells
- Neurogenetics
- Developmental Biology


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EMO 2017 saw Mitsubishi demonstrating innovative predictive maintenance possibilities for robots that can reduce operational costs, increase asset productivity and improve process efficiency. The cloud-based solution is based on the AI platform within IBM Watson, which enables the smart analysis of operational data to highlight maintenance requirements.
In addition, to increase the speed and efficiency of any necessary maintenance activities voice control and augmented reality have been implemented, providing opportunities for significant reductions in down-time.
Many companies today are still caught by surprise when machine failures occur. They tend to fix problems during unplanned down-time, or implement preventative maintenance based on set schedules or numbers of operational hours. However, with predictive maintenance, production problems can be highlighted long before they result in unplanned downtime or impact on yield. Maintenance operators can take corrective action before failure or before degraded machine performance results in faulty products being manufactured.
This latest solution from Mitsubishi Electric for predictive maintenance with robots utilises the AI platform within IBM Watson. The platform uses predictive maintenance models, digital simulation and extrapolation of trends to provide maintenance information based on actual usage and wear characteristics. This is particularly pertinent to robots, where users don't always appreciate that periodic maintenance is required.
Voice commands for Mitsubishi Electric robots
To increase the efficiency of maintenance operations, the demonstration at EMO 2017 highlighted the implementation of hands-free operation of the robot. Communications between the robot and the user via the cloud are two-way providing the basis for voice control of the robot. The demonstration also shows how additional support for maintenance activities can be provided, through a series of voice commands.
Augmented reality provides additional support for maintenance
Maintenance activities are optimised through the use of smart glasses, where the operator receives guidance on what tasks need to be performed. The glasses can show CAD drawings of the various robot parts, superimposed over the robot itself. The glasses can also show the maintenance manual and individual instructions.
As well as highlighting predictive maintenance, the demonstration on the Mitsubishi Electric stand at EMO 2017 showed how integrated safety can help manufacturers to optimise floor space, boost productivity and reduce down-time while maintaining a safe environment for operators.
Predictive maintenance and improved robot efficiency are parts of the key aspects for the digital transformation in manufacturing, and were some of the important themes of the Mitsubishi Electric stand at EMO 2017.
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This direct printing disperse dye ink is specially designed for textile printing. With the latest technology and premium raw material, the ink has perfect fluency, great color saturation and high fastness.
The direct printing disperse dye ink can be used to print on silk-like polyester, sports T-shirts, cycling jerserys, polyester bags, umbrella, shoes, decorative product and artwork etc.
The CMYK color model (process color, four color) is a subtractive color model, used in color printing, and is also used to describe the printing process itself. CMYK refers to the four inks used in some color printing:
Notice: Can not be mixed with other digital textile printing ink.
100ml, 500g, 1kg, 5kg, 20kg package optional.
Warranty: 01 years under temperature of 5∼25°C and out of direct sunlight.
Use up all the ink within 2 months after opening to esure optimum printing performance.
EPSON, FUJIFLIM DIMATIX, SEIKO SPT, KYOCERA, RICOH, KONICA MINOLTA etc.


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You can count on us to help you keep the septic system running smoothly at your home or business.
We install septic systems at new construction sits or existing properties and we can repair septic systems. Contact our office today to arrange an estimate.
Sewer line installation
Sewer line repairs
Delivery of landscaping materials
New septic systems installed
Water line replacement
Commercial and residential properties
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Arrange to use our flatbed van service, trucks, or storage trailers to deliver the supplies you need. We can provide you will fill and sand, black dirt, crushed rock, or other materials. Contact our office to have your questions answered about our delivery services.


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ask the guys who hang out at 1st and seaton why they disrespect our neighborhood
quick note: i'm just heading out the door to the february shaw neighborhood clean up. this morning when i woke up, i looked out the window, and one of the guys who always is hanging around on this corner was just finishing eating and drinking something.
he looked left, looked right, and when he was sure no one was watching him, tossed his garbage on the ground. then, he got up, walked over to the street drain, and tossed his bottle in it, ensuring it a safe journey to the anacostia river.
the kicker is that there are two garbage cans on the corner (which this guy usually leans on to watch traffic and women go by), and he couldn't take the effort to actually throw the garbage in one of those cans.
this is why we can't keep the neighborhood clean. people like these guys just don't give a damn.


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During an appearance Thursday with CNN's Jake Tapper, President-elect Donald Trump's incoming White House Press Secretary, Sean Spicer, vented a little on the liberal mainstream media's continued obsession with alleged hacking that "interfered" with the 2016 presidential election.
He made some pretty good points with regard to personal responsibility on the part of Democrats, as well as the media's seemingly one-way street when it comes to accountability:
To be clear, any attempt to hack or to do anything nefarious is wrong and illegal. But at some point—the question hasn't even been asked of the DNC—did you take basic measures to protect the data that was on there? Where's the responsibility of them to protect their systems?
No one wrote those emails, no one put a private server on there, and no one seems to have done the due diligence at the DNC to protect their own systems.
We need to have the intelligence community come forward publicly and on the record and make it clear exactly how this happened and who was responsible for it.
But right now, we continue to get unsourced media accounts for what the activity is. And I think that's not acceptable.
President Barack Obama has levied sanctions against the Russian government for its alleged role in the hacking of the DNC. And late Thursday, Trump issued a statement that he will meet with the intelligence community's representatives to discuss the matter:
It's time for our country to move on to bigger and better things. Nevertheless, in the interest of our country and its great people, I will meet with leaders of the intelligence community next week in order to be updated on the facts of this situation.
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text: I don't know what to do right now. I am really scared I am about to relapse. I went to do my blind weigh in today, my husband goes with me so he can know and email my nutritionist. However, I was anxious about weighing in. When we got home, I told him that it was bothering me and I thought knowing might help (I used to be able to know and be ok). I know logically it could be water, muscle and or fat but in my head I'm screaming pure fat because I ate some unhealthy things over the past few weeks. This sent me into a mental breakdown and I couldn't stop crying. Now I don't want to eat anything or speak of food. I ignored my hunger earlier and am putting dinner off as long as possible. I just don't know what to do, I know these thoughts are irrational and I need to fight back but I can't and just want to restrict so I can be in control. I don't want to relapse but at the same time restricting sounds so good right now... :(


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Staying Vigilant to Protect Your Health and Reputation
When an athlete competes in the UFC, they are not only accepting the opportunity to be in the spotlight, but also under the spotlight when it comes to clean sport. As such, athletes who are subject to the UFC Anti-Doping Policy have to be particularly vigilant about the substances they consume, medical treatment they receive, people they associate with, and competitive practices they accept. This vigilance means recognizing high risk behaviors and situations to minimize the risk of a positive test, adverse health event, or rule violation. While USADA is always available to help, athletes also need to be able to recognize clean sport red flags, so as to protect their health, their reputation, and their livelihoods.
#2: Thinking supplements are regulated to be safe
While athletes should consult health professionals about the use of supplements, it's equally important for athletes and their support personnel to understand that supplements always pose some level of risk.
In most countries, supplements are regulated post-market or not at all, which means that no regulatory body evaluates the contents safety or efficacy before they are sold to consumers. Unfortunately, supplements are sometimes sold without question or assessment until it becomes evident from consumer reports of negative health events that the product is harmful. Even then, supplements with harmful or illegal ingredients may remain on shelves for years.
It's also important to realize that supplement manufacturers may misidentify prohibited substances on labels, or they may fail to list prohibited substances altogether. Given these regulatory issues, it's a major red flag if supplements are touted to be reliably safe or free of side effects.
Also, be aware that the term natural doesn't always mean safe either. Using supplements is AT YOUR OWN RISK.


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When the Shoffner and Kalthoff family of companies merged, it was with the goal of being different — better than any mechanical or electrical contractor in the Southeast. From the essential to the most complex and technically challenging mechanical projects, SKMES is time and time again the contractor of choice.
Our reputation was built on the ability to "out perform" our competition. That reputation continues today.
SKMES offers our clients everything from pre construction to construction and commissioning to post construction services.
Our HVACR and Plumbing services include:
- Heating Ventilation Air Conditioning
- Plumbing / Mechanical Piping
- ASME Code Welding / Process Piping
- Certified Medical Gas Piping Installation
- Sheetmetal Ductwork Fabrication
- Round Spiral Ductwork Fabrication
- Stainless Steel Fabrication
- Piping Fabrication
- Kitchen and Ventilation Hoods
- Automated Temperature Controls
- HVACR Service / Plumbing Service
- Millwright
With 500+ employees, SKMES has the knowledge, experience and ability to provide HVACR and plumbing services for a variety of projects, including:
- Hospitals / Health Care Facilities
- Office Buildings / Corporate Headquarters
- Schools and University Projects
- Data and Call Centers
- Television Production Studios
- Convention Centers / Municipal Buildings
- Manufacturing and Distribution Facilities
- Penal Facilities
- Retail Centers / Stores / Malls
We have licenses in the following states:
HVAC and Plumbing: Tennessee, Kentucky, North Carolina and Virginia
HVACR: Alabama
HVAC and Boiler's: South Carolina
HVAC: Georgia
SKMES takes great pride in hearing our clients say, "We have a project. We need ShoffnerKalthoff to be part of our team." Many times these projects:
- are high profile…
- are best accomplished using one source for HVACR, plumbing and electrical service…
- have a tight schedule…
- require a large, highly skilled and trained workforce…
- require an excellent safety record…
- involve new technology…
- require intense attention to detail…
- or all of the above!
SKMES exceeds expectations every time.
Contact Us Today


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ColfaPig - Helping you Seize the Opportunity
7th June 2019
Canadian author Catherine DeVyre is quoted as saying "the opportunity of a lifetime must be grasped in the lifetime of that opportunity" and it appears that opportunity could be just around the corner for pig producers, so get ready.
With tightening global pork supply and price rises starting to be seen across Europe, it is up to us as producers to maximise the opportunity. One way that you can do that is via ColfaPig, which has been shown to deliver more piglets weaned and increased weaning and 10 week weights, allowing you to get more pigs through your unit quicker than before.
What is ColfaPig?
ColfaPig is a product for sows which consists of a specific mix of encapsulated short and medium chain fatty acids developed through 5 years of research that has been shown to:
- Increase fat and immunoglobulin production in sows colostrum,
- Increase piglet weaning weight
- Increase piglet viability, delivering an extra half piglet per sow.
The Science
Immunoglobulins are described in the Oxford Dictionary as proteins present in the serum and cells of the immune system, which function as antibodies. Given that initial protection for disease is passed through the colostrum in the first 24 hours via these immunoglobulins, the more we can provide the piglet, the better the chance they have of survival. ColfaPig was shown to increase 3 of these:
- IgG is the most clinically important immunoglobulin during the first week of life and represents between 80 and 85% of total immunoglobulins in serum and colostrum. It is the most important antibody in secondary response.
- IgA is the most important immunoglobulin in regard to mucosa activity and lactation. It prevents the attachment of antigens in gut walls and neutralizes the activity of some viruses, both inside and outside the epithelium cells, therefore is vital for helping prevent diarrhoea during the neonatal period
- IgM is the first antibody produced after an immune response and is essential for the primary response upon exposure to an antigen.
Through work carried out in conjunction with Queen's University Belfast we conducted proteomics research, which measures the expression of genes through proteins. The results showed a down regulation (decrease) in milk fat globule membrane (MFGM) proteins which are responsible for the change in the membrane around the fat in colostrum. By breaking down the membrane, the MFGM's reduce the amount of fat in colostrum. The downregulation in these means they are not as efficient at breaking membranes of fat globules so the fat stays in the colostrum, supporting the analysis that showed there was more fat in the colostrum (30% increase) of sows fed ColfaPig.
Why invest in ColfaPig in your diet?
ColfaPig costs approximately 35 pence per pig, but the results show a benefit of £4.50 - 5.00 per pig, representing a significant return on investment. That is before any potential price rises appear in the market.
Additionally, previous research has shown that piglets that had gained an extra 500g by weaning finished a week earlier, meaning that you can get more pigs through the system in the same accommodation space and improve your bottom line.
Ask yourself this: Can you maximise the opportunity without ColfaPig?


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Description: In This War Of Mine you do not play as an elite soldier, rather a group of civilians trying to survive in a besieged city; struggling with lack of food, medicine and constant danger from snipers and hostile scavengers. The game provides an experience of war seen from an entirely new angle.
- Inspired by real-life events
- Control your survivors and manage your shelter
- Craft weapons, alcohol, beds or stoves – anything that helps you survive
- Make decisions – an often unforgiving and emotionally difficult experience
- Randomized world and characters every time you start a new game
- Charcoal-stylized aesthetics to complement the game's theme
Minimum System Requirements:
OS: Windows XP SP3 (32 bit) / Vista
Processor: Intel(R) Core(TM)2 Duo 2.4, AMD Athlon(TM) X2 2.8 Ghz
Memory: 2 GB RAM
Graphics: Geforce 9600 GS, Radeon HD4000, Shader Model 3.0, 512 MB
DirectX: Version 9.0c
Sound Card: DirectX compatible
How to Install This War of Mine [Gamesena.com]
- Unrar.
- Burn or mount the image.
- Install the game.
- Play the game.
This War of Mine Free Download
This War of Mine Free Download


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Trilixton Muscle Builder Review – Testosterone Booster Truth Exposed – Italy, Sweden, Australia, Croatia, South Africa.
Trilixton Muscle Builder Trial – Hottest Muscle Enhancement Supplement – Shipping to Australia, France, South Africa, Italy, Croatia, Denmark, Norway, Slovakia, Ireland, Belgium, Sweden.
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What is Trilixton Muscle Builder – Italy, Sweden, Australia?
Trilixton Muscle Builder is a Male Muscle Enhancement Supplement. Having developed from Natural Ingredients, it aids you in building ripped body with leaner muscles. Trilixton Lean Muscle Formula is known to accelerate metabolism of proteins. Proteins are build blocks of lean and strong muscles.
To read more about Trilixton Muscle Builder and to make your Purchase, Please click on Banner Link below…
Trilixton Muscle Builder is described to be Shipping to Multiple Countries? Does it Deliver to my Nation?
Yes, Manufacturer is giving Free Trials of Trilixton Supplement to its Customers, 1 Bottle per Buyer. But, This Offer is not valid for Buyers from India, USA, Canada, UK.
Yes, Residents of Countries like South Africa, Australia, Italy, Sweden, Australia, France, Denmark, Norway, Belgium, Singapore, Switzerland, etc. can take advantage of this offer.
What are the Merits of Trilixton Muscle Builder – Italy, Sweden, Australia?
We have studied Trilixton Muscle Builder Reviews from Thousands of Buyers and Extracted following benefits of the Supplement…
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People and Many Internet Review Websites often Refer Free Trials as Scam. Is there any Truth behind it?
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UCO Bank Clerk Recruitment 2012. Kolkata-based public sector UCO Bank is inviting ON-LINE applications for Clerical Personnel Recruitment Project 2012 from Indian Citizen who have a passed the Common Written Examinations (CWE) conducted by Institute of Banking Personnel Selection (IBPS) and have a valid CWE Score Card issued by IBPS.
Important Information:
- Total Number of Vacancy : 1000 Posts.
- Starting date of Online Application : 16/05/2012
- Closing date of Online Application : 02/06/2012
- Eligibility Criteria (As On- 01.08.2011)
- 10+2 or Graduate
- Valid IBPS-Common Written Examination (CWE 2011) for Clerks Score Card.
Application Fees:
- For General & Others- Rs. 150
- For SC/ST- Rs. 50
Official Advertisement: http://
To apply online CLICK HERE