text:
|Mutation Type
|85,621,275 bp (GRCm38)
|Base Change
|C ⇒ T (forward strand)
|Gene Name
|ALMS1, centrosome and basal body associated
|Chromosomal Location
|85,587,531-85,702,753 bp (+)
|MGI Phenotype
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a protein containing a large tandem-repeat domain as well as additional low complexity regions. The encoded protein functions in microtubule organization, particularly in the formation and maintanance of cilia. Mutations in this gene cause Alstrom syndrome. There is a pseudogene for this gene located adjacent in the same region of chromosome 2. Alternative splice variants have been described but their full length nature has not been determined. [provided by RefSeq, Apr 2014]
PHENOTYPE: Homozygous null mice display obesity starting after puberty, hypogonadism, hyperinsulinemia, male-specific hyperglycemia, retinal dysfunction, and late-onset hearing loss. [provided by MGI curators]
|Accession Number
|Amino Acid Change
|Glutamine changed to Stop codon
|Institutional Source
|Beutler Lab
|Gene Model
|predicted gene model for protein(s): [ENSMUSP00000071904] [ENSMUSP00000148796]
|no structure available at present
|SMART Domains
Protein: ENSMUSP00000071904
Gene: ENSMUSG00000063810
AA Change: Q1028*
|Predicted Effect
|probably null
|Predicted Effect
|probably null
|Meta Mutation Damage Score
|Is this an essential gene?
|Non Essential (E-score: 0.000)
|Phenotypic Category
|Autosomal Recessive
|Candidate Explorer Status
|loading ...
|Single pedigree
Linkage Analysis Data
|Alleles Listed at MGI
All mutations/alleles(13) : Chemically induced (ENU)(2) Gene trapped(9) Spontaneous(1) Targeted(1)
|Lab Alleles
|Mode of Inheritance
|Autosomal Recessive
|Local Stock
|Live Mice, Sperm, gDNA
|MMRRC Submission
|Last Updated
|2022-04-12 3:40 PM by External Program
|Record Created
|2015-01-08 1:41 PM by Jeff SoRelle
|Record Posted
|Phenotypic Description
The ares phenotype was identified among N-nitroso-N-ethylurea (ENU)-mutagenized G3 mice of the pedigree R1804, some of which showed increased body weights compared to their littermates (Figure 1).
|Nature of Mutation
Whole exome HiSeq sequencing of the G1 grandsire identified 78 mutations. The increased body weight phenotype was linked to a mutation in Alms1: a C to T transition at base pair 85,621,275 (v38) on chromosome 6, or base pair 33,779 in the GenBank genomic region NC_000072 encoding Alms1. Linkage was found with a recessive model of inheritance (P = 1.971 x 10-5), wherein 5 variant homozygotes departed phenotypically from 11 homozygous reference mice and 6 heterozygous mice (Figure 2). The mutation corresponds to residue 3,197 in the mRNA sequence NM_145223 within exon 8 of 23 total exons.
The mutated nucleotide is indicated in red, and converts glutamine 1028 of the ALMS1 protein to a stop codon.
|Illustration of Mutations in
Gene & Protein
|Protein Prediction
Alms1 encodes Alström Syndrome 1 (ALMS1), which has a glutamine-rich segment (amino acids 2-80), a proline-rich segment (amino acids 90-113), a putative leucine zipper (amino acids), a large tandem repeat domain (TRD) comprised of 34 imperfect repeats of a 45-50-amino acid sequence (amino acids 440−1362), a histidine-rich region (amino acids 2582-2618), two putative nuclear localization signals, a serine-rich region, and an ALMS motif (amino acids 3124-3251) [Figure 3; (1-4)]. The functional significance of the domains of ALMS1 is unknown. Leucine zippers often function in protein-DNA or protein-protein interactions (3). The ALMS motif is also found in two other proteins, KIAA1731 and C10orf90, both of which are centriole proteins that are proposed to function in the formation and/or stability of cilia (1;2;4;5). The ares mutation results in coding of a premature stop codon after amino acid 1,028 within the TRD.
Alms1 is ubiquitously expressed (2;6). ALMS1 expression shows tissue-specific variability, with highest expression in the testis (2;3). ALMS1 localizes to centrosomes and basal bodies of cell cilia including those in human fetal pancreas, skeletal muscle, liver, kidney, hippocampus, adipocytes, within the hair cells of the developing and functionally mature cochlea, and supporting cells in the organ of Corti (4;5;7-9). During mitosis, ALMS1 localizes to the centrosomal spindle poles and during late mitosis ALMS1 localizes to the contractile ring and the cleavage furrow (10). Alms1 mRNA is upregulated in response to serum starvation (i.e., growth arrest) (11) and downregulated during adipogenesis (12). Alms1 transcription is also regulated by regulatory factor X proteins, which regulate genes of the ciliogenic pathway (13).
Cilia regulate many physiological processes including sensory (photoreception/vision, mechanosensation/hearing, and chemosensation/olfaction), embryonic development, and male fertility (14-16). Motile cilia facilitate the movement of fluids along cell surfaces as well as sperm motility, while nonmotile (primary) cilia function in the reception and transduction of extracellular signals. Primary cilia have several functions including the intraflagellar transport of signaling proteins and receptors needed for mechanosensation of lumenal flow in kidney tubules, olfaction, photoreception, and signaling through the sonic hedgehog (Shh), Wnt, and platelet-derived growth factor receptor pathways (17). Most cells have a single nonmotile primary cilium that protrudes from the apical face of the cell and is connected to the microtubule complex through the basal body. Bidirectional intraflagellar (i.e., anterograde versus retrograde) transport between the basal body and the distal tip of the cilium mediates the transport of proteins along the primary cilium. Anterograde transport is mediated by kinesin II, while retrograde transport is mediated by dynein [reviewed in (18)].
ALMS1 has putative roles in cell cycle regulation, cell migration, apoptosis, extracellular matrix production, ciliary assembly and/or function, adipogenesis, cytoplasmic microtubular organization, endosomal transport, and regulation of the transport of proteins between the cytoplasm and the ciliary axoneme (4-8;10;12;19;20). However, the precise role of ALMS1 in these processes is unknown. ALMS1 is not required for the initial development of cilia, but is required to maintain the structural and functional integrity of the cilia and/or for postnatal biogenesis of the cilium [Figure 4; (9)]. The C-terminus of ALMS1 interacts with the cytoskeletal actin-binding proteins α-actinin 1 and α-actinin 4 and other components of the endosomal recycling pathway including Huntington-associated protein isoform A (HAP1A), Rab interacting lysosomal protein-like 1 (RILPL1), myosin Vb (MYO5B; see the record new_gray for information about MYO5A), ring finger protein 31 (RNF31), RAD50 interactor 1 (RINT1), and CBP interacting protein 3 (CIP3 or EXOSC8) (10). Two of the ALMS1-interacting proteins, MYO5B and α-actinin isoform 4, are subunits of the cytoskeleton-associated recycling or transport (CART) complex, which functions in the constitutive recycling of receptors (e.g., the transferrin receptor and the β2-adrenergic receptor) from the early endosomes to the plasma membrane (21). Collin et al. propose that ALMS1 may be a component of the CART complex to mediate movement of endosomes along actin filaments to the plasma membrane (10). ALMS1 is also proposed to function in normal axonal development and migration through the regulation of neuronal intraflagellar transport. ALMS1 has a putative function in maintaining intraflagellar transport in hypothalamic-coupled neurons to regulate hypothalamic satiety and hunger (22). ALMS1 is required for the proper anchoring of C-NAP1, a regulator of centrosome organization during mitosis, at the distal end of the centriole (1). Loss of ALMS1 expression results in reduced expression levels of C-NAP1 and subsequent increased centrosome splitting, a necessary process for anaphase chromosomal division, as well as subsequent defects in cilium stability or formation (1). Short interfering RNA (siRNA)-mediated knockdown of Alms1 in mouse inner medullary collectin duct (mIMCD3) cells resulted in mislocalization of acetylated tubulin in the cells (8). However, the transcriptional program that accompanies cilia biogenesis of kidney epithelial cells was not changed upon loss of Alms1 expression (8). In addition, siRNA-mediated Alms1 knockdown in cultured neonatal mouse cardiomyocytes led to increased cell cycle progression (i.e., an increased percentage of cardiomyocytes in G2/M phases) and proliferation (19).
Homozygous or compound heterozygous mutations in ALMS1 that typically result in coding of a premature stop codon and coding of a truncated protein are linked to Alström syndrome (OMIM: #203800; (2;23)]. Alström syndrome has variable symptoms including childhood obesity due to an excess accumulation of subcutaneous adipose tissue, hyperinsulinemia, acanthosis nigricans (a marker of severe insulin resistance), type 2 diabetes mellitus, hypertriglyceridemia that can lead to acute pancreatitis, hypothyroidsism, growth hormone deficiency, sensorineural hearing loss, and progressive rod-cone dystrophy leading to blindness [(24); reviewed in (25;26)]. Approximately 70% of patients with Alström syndrome also have dilated cardiomyopathy during infancy or adolescence [(19); reviewed in (25)]. In addition, many patients have hepatic and urologic dysfunction as well as renal failure and systemic fibrosis with age [reviewed in (25)]. Patients exhibit hypogonadotropic hypogonadism leading to infertility and female patients have symptoms of polycystic ovary syndrome and hyperandrogenism (25;27). The symptoms of Alström syndrome lead to high morbidity and reduced life expectancy (25).
Several Alms1 mutant mouse models (fat aussie (foz), Alms1L2131X, and Alms1-/-) have been characterized. The foz phenotype was linked to a spontaneous 11-base pair (bp 3918-3928) deletion within exon 8 of Alms1 resulting in a frame-shift and coding of a premature stop codon (28). The ENU-induced Alms1 mutation, Alms1L2131X, resulted in premature truncation of the protein at amino acid 2,130 (8). The Alms1-/- model is a gene-trapped Alms1 allele (6;29). All of the mouse models exhibited rapid weight gain due to an increase in body fat and increased eating at weaning so that by 8 weeks of age they were significantly heavier than wild-type mice (6;8;9;29;30). All of the mutant Alms1 alleles also resulted in hyperinsulinemia, increased cholesterol levels (total and HDL), moderate late-onset (after ~16 weeks) diabetes only in the male mice, steatosis of the liver, hyperplastic pancreatic islets, and hypogonadism leading to infertility in the male mice (6;8;28-30). The Alms1-/- retina exhibited age-related degeneration and defective transport of rhodopsin (see the record for Bemr3), the major protein in rod photoreceptor outer segment discs; membrane-bound vesicles accumulated in the distal portion of the inner segments near the connecting cilium (8). Alms1 mutations also led to age-related cochlear degeneration and hearing loss. The Alms1-/- mice exhibited misshapen stereociliary outer hair bundles and mislocalized kinocilia; the inner hair cells bundles in the Alms1-/- mice were largely normal (5). Young female foz/foz mice were fertile, but litter sizes were smaller than those of wild-type or heterozygous mice (28). After the female mice became obese, they became infertile and the ovaries were devoid of corpora lutea, indicating an anovulatory state (28). The foz/foz mice also exhibited a reduction in neurons that displayed cilia marked with adenylyl cyclase 3, a signaling protein that regulates obesity, as well as a reduction in cilia that contained the appetite-regulating proteins, Mchr1 and Sstr3 (9). When fed a high-fat diet the foz/foz mice undergo transition of steatosis to severe fibrosing steatohepatitis that includes the majority of hepatocytes exhibiting severe ballooning degeneration, lobular inflammation, and pericellular and pericentral fibrosis (30). The transition after high-fat diet was associated with higher hepatic triglyceride levels compared to chow-fed foz/foz mice (30). Total GLUT4 content, insulin-stimulated GLUT4 translocation, and glucose uptake was reduced in the Alms1-/- mice indicating that ALMS1 mediates glucose homeostasis through the GLUT4 trafficking pathway (29). The Alms1-/- mice could respond to insulin by stimulating AKT phosphorylation indicating that the impaired GLUT4 translocation is downstream of AKT activation or is independent of AKT signaling.
|Putative Mechanism
Centrosome and basal body dysfunction as a result of mutations in Alms1 are predicted to lead to the pathogenesis of obesity, insulin resistance, and type 2 diabetes. Although the exact function of ALMS1 is unknown, it has been shown to be essential in weight regulation. Other ALMS1-related phenotypes have not been tested or observed in ares, but the weight gain phenotype indicates that the mutation results in loss-of-function.
PCR Primer
ares_pcr_F: AGCAGCCTATGTCAGATAGTCAG
ares_pcr_R: AGAGCCAGAGCCTACTGATTTC
Sequencing Primer
ares_seq_F: GCCTATGTCAGATAGTCAGCGAAC
ares_seq_R: CCAGAGCCTACTGATTTCAAAAATAC
PCR program
The following sequence of 401 nucleotides is amplified (chromosome 6, + strand):
1 agcagcctat gtcagatagt cagcgaacta aaggtcacaa agaatcagat gttcctggac
Primer binding sites are underlined and the sequencing primers are highlighted; the mutated nucleotide is shown in red.
1. Knorz, V. J., Spalluto, C., Lessard, M., Purvis, T. L., Adigun, F. F., Collin, G. B., Hanley, N. A., Wilson, D. I., and Hearn, T. (2010) Centriolar Association of ALMS1 and Likely Centrosomal Functions of the ALMS Motif-Containing Proteins C10orf90 and KIAA1731. Mol Biol Cell. 21, 3617-3629.
2. Collin, G. B., Marshall, J. D., Ikeda, A., So, W. V., Russell-Eggitt, I., Maffei, P., Beck, S., Boerkoel, C. F., Sicolo, N., Martin, M., Nishina, P. M., and Naggert, J. K. (2002) Mutations in ALMS1 Cause Obesity, Type 2 Diabetes and Neurosensory Degeneration in Alstrom Syndrome. Nat Genet. 31, 74-78.
3. Hearn, T., Renforth, G. L., Spalluto, C., Hanley, N. A., Piper, K., Brickwood, S., White, C., Connolly, V., Taylor, J. F., Russell-Eggitt, I., Bonneau, D., Walker, M., and Wilson, D. I. (2002) Mutation of ALMS1, a Large Gene with a Tandem Repeat Encoding 47 Amino Acids, Causes Alstrom Syndrome. Nat Genet. 31, 79-83.
4. Hearn, T., Spalluto, C., Phillips, V. J., Renforth, G. L., Copin, N., Hanley, N. A., and Wilson, D. I. (2005) Subcellular Localization of ALMS1 Supports Involvement of Centrosome and Basal Body Dysfunction in the Pathogenesis of Obesity, Insulin Resistance, and Type 2 Diabetes. Diabetes. 54, 1581-1587.
5. Jagger, D., Collin, G., Kelly, J., Towers, E., Nevill, G., Longo-Guess, C., Benson, J., Halsey, K., Dolan, D., Marshall, J., Naggert, J., and Forge, A. (2011) Alstrom Syndrome Protein ALMS1 Localizes to Basal Bodies of Cochlear Hair Cells and Regulates Cilium-Dependent Planar Cell Polarity. Hum Mol Genet. 20, 466-481.
6. Collin, G. B., Cyr, E., Bronson, R., Marshall, J. D., Gifford, E. J., Hicks, W., Murray, S. A., Zheng, Q. Y., Smith, R. S., Nishina, P. M., and Naggert, J. K. (2005) Alms1-Disrupted Mice Recapitulate Human Alstrom Syndrome. Hum Mol Genet. 14, 2323-2333.
7. Andersen, J. S., Wilkinson, C. J., Mayor, T., Mortensen, P., Nigg, E. A., and Mann, M. (2003) Proteomic Characterization of the Human Centrosome by Protein Correlation Profiling. Nature. 426, 570-574.
8. Li, G., Vega, R., Nelms, K., Gekakis, N., Goodnow, C., McNamara, P., Wu, H., Hong, N. A., and Glynne, R. (2007) A Role for Alstrom Syndrome Protein, alms1, in Kidney Ciliogenesis and Cellular Quiescence. PLoS Genet. 3, e8.
9. Heydet, D., Chen, L. X., Larter, C. Z., Inglis, C., Silverman, M. A., Farrell, G. C., and Leroux, M. R. (2013) A Truncating Mutation of Alms1 Reduces the Number of Hypothalamic Neuronal Cilia in Obese Mice. Dev Neurobiol. 73, 1-13.
10. Collin, G. B., Marshall, J. D., King, B. L., Milan, G., Maffei, P., Jagger, D. J., and Naggert, J. K. (2012) The Alstrom Syndrome Protein, ALMS1, Interacts with Alpha-Actinin and Components of the Endosome Recycling Pathway. PLoS One. 7, e37925.
11. Yabuta, N., Onda, H., Watanabe, M., Yoshioka, N., Nagamori, I., Funatsu, T., Toji, S., Tamai, K., and Nojima, H. (2006) Isolation and Characterization of the TIGA Genes, Whose Transcripts are Induced by Growth Arrest. Nucleic Acids Res. 34, 4878-4892.
12. Romano, S., Milan, G., Veronese, C., Collin, G. B., Marshall, J. D., Centobene, C., Favaretto, F., Dal Pra, C., Scarda, A., Leandri, S., Naggert, J. K., Maffei, P., and Vettor, R. (2008) Regulation of Alstrom Syndrome Gene Expression during Adipogenesis and its Relationship with Fat Cell Insulin Sensitivity. Int J Mol Med. 21, 731-736.
13. Purvis, T. L., Hearn, T., Spalluto, C., Knorz, V. J., Hanley, K. P., Sanchez-Elsner, T., Hanley, N. A., and Wilson, D. I. (2010) Transcriptional Regulation of the Alstrom Syndrome Gene ALMS1 by Members of the RFX Family and Sp1. Gene. 460, 20-29.
14. Berbari, N. F., O'Connor, A. K., Haycraft, C. J., and Yoder, B. K. (2009) The Primary Cilium as a Complex Signaling Center. Curr Biol. 19, R526-35.
15. Gerdes, J. M., Davis, E. E., and Katsanis, N. (2009) The Vertebrate Primary Cilium in Development, Homeostasis, and Disease. Cell. 137, 32-45.
16. Goetz, S. C., and Anderson, K. V. (2010) The Primary Cilium: A Signalling Centre during Vertebrate Development. Nat Rev Genet. 11, 331-344.
17. Singla, V., and Reiter, J. F. (2006) The Primary Cilium as the Cell's Antenna: Signaling at a Sensory Organelle. Science. 313, 629-633.
18. Rosenbaum, J. L., and Witman, G. B. (2002) Intraflagellar Transport. Nat Rev Mol Cell Biol. 3, 813-825.
19. Shenje, L. T., Andersen, P., Halushka, M. K., Lui, C., Fernandez, L., Collin, G. B., Amat-Alarcon, N., Meschino, W., Cutz, E., Chang, K., Yonescu, R., Batista, D. A., Chen, Y., Chelko, S., Crosson, J. E., Scheel, J., Vricella, L., Craig, B. D., Marosy, B. A., Mohr, D. W., Hetrick, K. N., Romm, J. M., Scott, A. F., Valle, D., Naggert, J. K., Kwon, C., Doheny, K. F., and Judge, D. P. (2014) Mutations in Alstrom Protein Impair Terminal Differentiation of Cardiomyocytes. Nat Commun. 5, 3416.
20. Zulato, E., Favaretto, F., Veronese, C., Campanaro, S., Marshall, J. D., Romano, S., Cabrelle, A., Collin, G. B., Zavan, B., Belloni, A. S., Rampazzo, E., Naggert, J. K., Abatangelo, G., Sicolo, N., Maffei, P., Milan, G., and Vettor, R. (2011) ALMS1-Deficient Fibroblasts Over-Express Extra-Cellular Matrix Components, Display Cell Cycle Delay and are Resistant to Apoptosis. PLoS One. 6, e19081.
21. Yan, Q., Sun, W., Kujala, P., Lotfi, Y., Vida, T. A., and Bean, A. J. (2005) CART: An Hrs/actinin-4/BERP/myosin V Protein Complex Required for Efficient Receptor Recycling. Mol Biol Cell. 16, 2470-2482.
22. Mok, C. A., Heon, E., and Zhen, M. (2010) Ciliary Dysfunction and Obesity. Clin Genet. 77, 18-27.
23. Joy, T., Cao, H., Black, G., Malik, R., Charlton-Menys, V., Hegele, R. A., and Durrington, P. N. (2007) Alstrom Syndrome (OMIM 203800): A Case Report and Literature Review. Orphanet J Rare Dis. 2, 49.
24. Marshall, J. D., Bronson, R. T., Collin, G. B., Nordstrom, A. D., Maffei, P., Paisey, R. B., Carey, C., Macdermott, S., Russell-Eggitt, I., Shea, S. E., Davis, J., Beck, S., Shatirishvili, G., Mihai, C. M., Hoeltzenbein, M., Pozzan, G. B., Hopkinson, I., Sicolo, N., Naggert, J. K., and Nishina, P. M. (2005) New Alstrom Syndrome Phenotypes Based on the Evaluation of 182 Cases. Arch Intern Med. 165, 675-683.
25. Marshall, J. D., Beck, S., Maffei, P., and Naggert, J. K. (2007) Alstrom Syndrome. Eur J Hum Genet. 15, 1193-1202.
26. Girard, D., and Petrovsky, N. (2011) Alstrom Syndrome: Insights into the Pathogenesis of Metabolic Disorders. Nat Rev Endocrinol. 7, 77-88.
27. Dunaif, A. (1997) Insulin Resistance and the Polycystic Ovary Syndrome: Mechanism and Implications for Pathogenesis. Endocr Rev. 18, 774-800.
28. Arsov, T., Silva, D. G., O'Bryan, M. K., Sainsbury, A., Lee, N. J., Kennedy, C., Manji, S. S., Nelms, K., Liu, C., Vinuesa, C. G., de Kretser, D. M., Goodnow, C. C., and Petrovsky, N. (2006) Fat Aussie--a New Alstrom Syndrome Mouse Showing a Critical Role for ALMS1 in Obesity, Diabetes, and Spermatogenesis. Mol Endocrinol. 20, 1610-1622.
29. Favaretto, F., Milan, G., Collin, G. B., Marshall, J. D., Stasi, F., Maffei, P., Vettor, R., and Naggert, J. K. (2014) GLUT4 Defects in Adipose Tissue are Early Signs of Metabolic Alterations in Alms1GT/GT, a Mouse Model for Obesity and Insulin Resistance. PLoS One. 9, e109540.
|Science Writers
|Anne Murray
|Peter Jurek
|Zhe Chen, Jeff SoRelle, Noelle Hutchins


text: Home Lifestyle Auto Review: The Aston Martin Virage The Aston Martin Virage is designed to get you quickly from point A to B in comfort and style. That it does with aplomb. by Guido Duken June 9, 2011 The Andalusian town of Ronda, about 100 kilometres northwest from Malaga, is as historic as it is beautiful. The Guadalevin River runs through the city, dividing it in two and carving out the steep 100-metre deep El Tajo canyon upon which the city perches. Looking out from this lofty perch all you see is rolling hills and roads that snake, carve and hug the countryside like mad pieces of spaghetti. In other words, if you want to seriously drive a car and test its limits, this is the place to do it. The Islamic poet Salih ben Sharif al-Rundi was born in Ronda, and if he had laid his eyes on the Aston Martin Virage it might have inspired some epic verse. The Virage is a moving work of art with its clean lines, muscular stance and aggressive front. The attention to detail is immaculate both inside and outside and the Aston Martin team was beaming like proud parents as they showed off their latest addition to the family. Under the bonnet the Virage has a V12 6.0-litre engine that delivers 490bhp and 570nm of torque that propels the Aston from 0-100km/h in 4.6 seconds. The top speed is a sizzling 299km/h. Keeping control of all that speed and power are huge carbon ceramic brakes, a very sweet six-speed Touchtronic 2 automatic transmission and a new Adaptive Damping System. Those winding Spanish B roads didn't know what hit them. The Virage is perfectly well behaved, tackling corners confidently and cruising with ease. But when you push the accelerator the V12 barks with excitement and the unleashed torque slightly lifts the nose and pushes you back in your seat. Stuck behind a caravan of cars with only 30 metres of straight road ahead? No problemo! The Virage accelerates so quickly it might as well be a kilometre. That, in a nutshell, is the beauty of the Virage. It is an extremely comfortable GT (gran turismo) with the body and brawn of a finely honed athlete. You can drive it any which way you want and it always delivers exactly what you want, when you want it. That's what makes driving it so much fun. The only downside is that all that pedigree will set you back around $240,000. Tags Motoring 0 Comments Share Tweet Share Share You might also like Mercedes-Benz teams up with designer Virgil Abloh to create one-off G-Class SUV Range Rover introduces 50th anniversary limited edition SUV Fiat Chrysler Automobiles and Groupe PSA merged company to be called Stellantis Mercedes-Benz And Nvidia to collaborate on automated driving technology

subset: commoncrawl


text:
Our History:
B&W Charters was founded in Kalamazoo, Michigan, in 1983 by Paul Best and Gene Wright. The original goal was to provide exclusive top quality and personalized motorcoach charter service to the Kalamazoo area. Today the company continues to be headquartered in Kalamazoo, Michigan with expanded service to include all of southwestern Michigan and beyond.
Our Employees:
B&W Charters is managed and staffed by professional, well-trained, conscientious employees. Each associate shares company values and is committed to service excellence. All drivers are scheduled for refresher training and safety seminars with our safety director throughout the year. Wherein safe operating practices are enhanced and updated. In addition to this, all drivers are subject to scheduled ride and road checks of their performance. These ride checks are then reviewed afterwards with the operator, visiting any errors and reinforcing professional, safe driving habits. All drivers are also subject to federally-mandated drug and alcohol testing on a non-suspicion based random basis.
Our Motto:
"For Motorcoach Charters and Tours . . . B&W, the Best Service for the Wright Charter"Consistent with the names of the company founders


text:
Prometheus Financial Advisory's team of professionals specializes in providing business and economic advisory services in connection with legal and regulatory procedures, including preparation of economic and business opinions, as well as giving evidence as expert witnesses. The firm's CEO, Yuval Zilberstein, heads this activity and regularly gives evidence in court as an expert witness.
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The firm has accumulated tens of years of experience of preparing expert opinions that are backed by credible arguments provided as part of legal proceedings involving leading public companies, as well as private companies and entities. This experience has been converted into the proven ability to defend the opinion when giving evidence as an expert witness (against the opinion presented by the other party to the proceedings).
When necessary, the expert opinion is offered in collaboration with the client's attorneys, and entails the formation of well-defined, convincing, clear and creative economic arguments. This process incorporates in-depth business, financial and accounting knowledge that is made comprehensible to readers who are not financial and/or accounting experts.


text:
- Apache Storm Tutorial
- Apache Storm - Home
- Apache Storm - Introduction
- Apache Storm - Core Concepts
- Apache Storm - Cluster Architecture
- Apache Storm - Workflow
- Storm - Distributed Msging System
- Apache Storm - Installation
- Apache Storm - Working Example
- Apache Storm - Trident
- Apache Storm in Twitter
- Apache Storm in Yahoo! Finance
- Apache Storm - Applications
- Apache Storm Useful Resources
- Apache Storm - Quick Guide
- Apache Storm - Useful Resources
- Apache Storm - Discussion
Apache Storm - Applications
Apache Storm framework supports many of the today's best industrial applications. We will provide a very brief overview of some of the most notable applications of Storm in this chapter.
Klout is an application that uses social media analytics to rank its users based on online social influence through Klout Score, which is a numerical value between 1 and 100. Klout uses Apache Storm's inbuilt Trident abstraction to create complex topologies that stream data.
The Weather Channel
The Weather Channel uses Storm topologies to ingest weather data. It has tied up with Twitter to enable weather-informed advertising on Twitter and mobile applications. OpenSignal is a company that specializes in wireless coverage mapping. StormTag and WeatherSignal are weather-based projects created by OpenSignal. StormTag is a Bluetooth weather station that attaches to a keychain. The weather data collected by the device is sent to the WeatherSignal app and OpenSignal servers.
Telecom Industry
Telecommunication providers process millions of phone calls per second. They perform forensics on dropped calls and poor sound quality. Call detail records flow in at a rate of millions per second and Apache Storm processes those in real-time and identifies any troubling patterns. Storm analysis can be used to continuously improve call quality.
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text:
Of Bones and Blessings, Cursings and Curings and Walking in Between
ear Miracles: On this day when the veils are especially thin I am thinking of the old saying that in order to know how to heal you must also know how to hex or in order to cure you must be able to curse. Or how about this one from a 14th century Scottish man referring to a local cunning woman:
"She was either a witch or a woman of God."
Any way you slice it, the line between benevolent and baneful magics is ever present and thin — but on days like today it is especially so.
I remember reading in Brian Froud and Alan Lee's Book Faeries about the Scottish tradition of the Seelie and Unseelie Court — the belief that the Unseelie court of faerie ruled the dark part of the year from Samhain until Midwinter.
The Unseelie court was believed to be composed of the more mischief-making or in some cases downright harmful and deadly faerie creatures. In honor (and fear) of their reign, farmers would leave untouched any crop that had not been harvested by the evening of October 31st-it was considered forfeit — an offering for the faeries and not fit for human consumption.
This is just one of a plethora of traditions found around the world that recognizes the change in power and energy as the life/death/life cycle circles around and around spiraling into the heavens and down into the dark earth. It is those apparently opposing forces that are also at play with the curing and cursing dynamic.
Curing and Killing in Plant Medicine and Magic
As a student of Ancient Greek, among other things, the issue of cursing and curing comes out of language — as is well known in entheogenic circles, the Greek word for poison is the same word for medicine (pharmakon) — where, etymologists may be able to see, we get current words like "pharmacy."
Many of our natural poisons have incredibly potent healing properties. Consider the digitalis derived from Purple Foxglove (Digitalis Purpurea) that can stop a heart or assist in curing congestive heart failure, the highly toxic Black Henbane (Hyosyamus Niger) that traditionally has worked with to induce visionary trance and the sensation of flying but also as a topical analgesic to relieve pain and swollen joints.
Monkshood (Aconitum) is deadly in the right dose but has been used medicinally for thousands of years, and Belladonna (Atropa Belladonna) is the source for the drug Atropine.
Perhaps most famously, snake antivenins are usually composed from the original venom itself.
Knowledge of the Poison Path (as Dale Pendell terms it) is sought out for many reasons — people want to understand these plants and poisons that have held such allure through time and history, people want to experience hallucinations or get high for recreational reasons, devotees wish to engage in ritual usages –some of which are millenia old, but as Aldous Huxley famously wrote when high on Mescaline, derived from yet another potent plant — Peyote (Lophophora Williamsii), the doors of perception are opened.
The Poison Path is a rich place to begin any consideration of the relationship between curing and cursing because our first and truest teacher — Nature — often combines these elements in the same being. A little too much of that and you are sick or dying, but just the right amount and you can be saved, pain-free, wholesome.
What I have learned in my own practice is that these poisons/medicines have the ability not only to cure or kill, they can pierce through our current perceptions and reveal new possibilities that were hidden behind a veil of illusion.
The idea of being pierced is as old as cupid and even older, I feel it finds one of its most beautiful expressions in the Sacred Heart of Jesus Christ In Catholic and folk-Catholic-magic traditions the sacred and pierced heart is a requisite for curing or cursing — I believe that in magic period a pierced heart is a requisite because the pierced and sacred heart represents a heart that has been cut, punctured, wounded in some way and yet is still vital, still beating, still blessing, sacral, and sacred.
This sacred heart — often depicted as wrapped in the crown of thorns worn by Christ during the Passion, is pierced by the suffering of humanity as well as the sufferings, large and small, that we all experience in our daily lives. As the heart is punctured so too our sense of safety and security, as the heart is punctured so too our sense of isolation that is questioned, as the heart is punctured so too our moments of selfishness illuminated and called out for what they really are. The pierced heart is experienced by the one who sees beyond the veil — through life experience, through innate wisdom, through plant magic, and most essentially through ineffable mystery.
It is a theme we see in baneful magic again and again — the piercing and puncturing of a heart to wound, curse, or in some cases sting into regret and recognition, and yet having a pierced heart is absolutely emphasized in healing and love work as well.
For me, the iconography of the pierced heart has always spoken not only to the relationship between cursing and curing — but also to the relationship between life and death. And what better time or season to celebrate the way that those two forces dance with each other?
Living in the Southwest where the harvest cycles definitely do not follow that of the Celtic year, I know our own land wights and spirits are on a slightly different calendar, but we have our own versions of the life/death energies — and one of the most popular dualities right now if that of Nuestra Senora de Guadalupe: Our Lady of Guadalupe & her skull sister Santisima (or in some areas Santa) Muerte-Most Holy Death or Our Lady Most Holy Death.
Our Lady of Guadalupe and Santisima Muerte
These two are actually sister figures — both based on ancient Nahuatl Goddesses. Our Lady of Guadalupe is the Catholicized incarnation of Tonantzin while Santisima Muerte is a Catholic-folk and increasingly so-called "narco" saint based on the Lady of Death, Mictecacihuatl. In Nahuatl-Aztec culture Tonantzin was an earth and fertility Goddess, bringing life giving rains to the hills, valley, and canyons, and bestowing life giving properties on the land and the people. To include our sacred plant theme, some believe that Tonantzin is specifically affiliated with the Agave plant and its various ritual and ecstatic uses. Like the Summerian Inanna and her skull sister Ereshkigal — Tonantzin had a relationship with her own shadow sister, Mictecacihuatl, the Lady of Death. In Meso-American culture death was highly esteemed because the ancestors were seen to be guiding forces of both wisdom and prophecy. Therefore the Lord and Lady of Death had to be propitiated whenever someone passed beyond the veil so that they would accept their soul and as it were, make a home for them. Mictecacihuatl possesses the guise of Santisima Muerte — who has interestingly become increasingly allied with those involved in the illegal drug and arms trades in Mexico and the US-Mexican border — but she is also known throughout the Southwest simply as La Huesera –– the bone woman — and is venerated as such, the Mother of death who sings life into the bones so that the cycle may spiral out yet again.
I am always interested in ideas that are apparent opposites but underneath share a solid unity with one another. In the case of hexing and healing or cursing and curing I believe that this foundation is strongly present and the folk magician should at the very least understand the relationship — perhaps as the winds blow from the otherworld into our own they will carry a bit of wisdom with them to aid us in our efforts.
May you all have a beautiful Halloween, Blessed Samhain, and delightful Dia de los Muertos!
A version of this article was printed in Amulet Magazine's Fall 2013 issue.


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Elevate Chicago Dance 2018
@ Chicago Cultural Center
78 E Washington St, Chicago, IL 60602
Opening Sunday, October 21st, from 10AM - 5PM
Chicago Dancemakers Forum celebrates its 15th Anniversary year with Elevate Chicago Dance 2018, a full-day of free performances, installations, workshops and discussions by 45 Chicago dancemakers on Sunday, October 21 at the Chicago Cultural Center, in partnership with the City of Chicago's Department of Cultural Affairs and Special Events (DCASE).
The broadly defined theme of the day explores intersections between Dance, Space, Race, and Place. The Elevate Chicago Dance 2018 artists, through a diverse range of dance and interdisciplinary works, make connections with current ideas about the dynamics between race, social spaces, and personal and body histories. For artists as well as for public audiences, the cultural, political and architectural history of the Chicago Cultural Center building is a powerful setting for these relevant considerations. Dance performances will activate all the floors and multiple public areas of the landmark Chicago Cultural Center, including the Claudia Cassidy Theater, GAR Hall, the Dance Studio, and Preston Bradley Hall.
The Elevate Chicago Dance 2018 participating artists and companies include:
Ayodele Drum & Dance
Elysia C. Banks/ Banks Performance Project
BraveSoul Movement
Paige Caldarella
Peter Carpenter
Asimina Chremos
Margi Cole
Deeply Rooted Dance Theater
Emma Draves
Joanna Furnans
Brittany Harlin
Hedwig Dances
HoneyPot Chicago
A House Unbuilt/Victoria Bradford
J'Sun Howard
Ayako Kato/Art Union Humanscape
Erin Kilmurray
Ginger Krebs
Fujima Yoshinojo/Rika Lin
Lucky Plush Productions
Molly Shanahan/Mad Shak
Mandala Arts
Carole McCurdy
Mordine & Company
Margaret Morris
Erica Mott Productions
Nadia Oussenko
Onye Ozuzu/Ozuzu Dances
Po'Chop/Jenn Freeman
Nico Rubio/333
Same Planet Performance Project
Darling Shear
Catherine Sullivan
Synapse Arts
The Humans
The Seldoms
Monica Thomas
Visceral Dance Chicago
Rob Welcher
Anna Martine Whitehead
Nejla Yatkin/NY2Dance
Megan Young
Sara Zalek
Produced in connection with Elevate Chicago Dance 2018 will be a Crystal Anniversary Brunch with Honorary Chair, Chicago Mayor Rahm Emanuel, and Honorary Co-Chairs: Michelle Boone, Dr. Kwang-Wu Kim, and Roell Schmidt.


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Friday, May 11, 2012
"The measure of who we are is what we do with what we have." V. Lombardi
It takes a lot of training and mental fortitude to leave one's family behind unsure what their foreseeable future might hold while you rush to do your job and save the free world from godless commies...
Sorry. I guess that brainwashing sticks with a person long after their time in service is done.
Yes, I have an emergency bag packed and plan in place in the event of disaster or revolution. As a loving husband and father of three, I wouldn't feel comfortable not being prepared. I've gone as far as preparing a Survival Package that contains crucial information that my family will need to know in the event..well...you know...I don't make it. Shelter, water and food plus a driving desire to survive can bring a person through circumstances that might be unimaginable to them today.
So, what would be my five 'extra' things I would grab before leaving? Actually, I've already thought this one through:
1. My personal Bible. I wrote about this Stone of Remembrance last November. We've been through tough times together already, and I know the reassuring message contained in its pages would resonate strongly in the most dire times.
2. A family picture album. I have one in mind already. Hope is a very powerful thing especially in a survival situation. A picture is worth a thousand words is cliche for a reason.
3. My grandfather's pocketknife. Granted, it wouldn't be much of a tool and far more effective tools are already in the emergency bag, but these single inheritance from my ancestry has not only a ton of stories packed inside...but also a lifetime of wisdom and life lessons.
4. Several classic novels from the bookcase. Without the blitz of media-laced electronic entertainment, boredom will take hold quick. A nice change of pace from daily biblical stories would be an interjection of modern culture. What better way to keep that culture alive than nightly reading aloud from Steinbeck, Faulkner or Hemingway to pass the time.
5. My journal. While my story is by no means special, it is uniquely mine. For the several years I've documented my thoughts, prayers, hopes and dreams, those pages are a glance into who I truly am. I would not only want my girls to have those pages, but to pass them on to their children to show them that loving God with all your heart is not just a memorable passage from the Good Book, but a true way of life. A forever changing way of life. I'm pretty sure that comes across loud and clear to this point of the journal.
I don't consider myself a survivalist by any stretch of the imagination. I'm also not an alarmist, but I do realize we live in an unstable world where politics or nature itself can explode at any given moment. Here's one last cliche to chew on:
Better safe than sorry
One thing I know with absolute certainty, regardless of my circumstances, God is with me always.
Posted by Tony C
Labels: Stones of Remembrance, Tony C
1 comment:
Your blog sparked in me a thought that I know I don't fully comprehend' That is, what it is like for a person in the Military to suddenly leave their families. Also the ramifications of that absence on their loved ones.
I love watching the surprise reunions of the moms and dads and spouses as they return home. In reality there is so much emotion going on from the assignment announcement and the hoped for return.
Always enjoy your post.
Thank you for your service to our country.
- Saturday, May 12, 2012
Subscribe to: Post Comments (Atom)


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Off-Page Optimization
What is Off-Page Optimization?
Off-page optimization traditionally focused on improving keyword ranking and rank acquisition. More current off-page SEO optimization techniques help maximize search and brand exposure and manage the business' online reputation via incoming links and other factors that impact search results webpage indexing. Linking domains and social media is very effective but mostly out of the inbound marketer's control. Off-page optimization manages online reviews and reputations, helps drive local searches, improves local citations (names, addresses, phone numbers, etc.), link acquisition, and local business coverage.


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I wonder why the Pope didn't force Kasper, and a few others, into retirement?
Cardinal Kasper is calling for a more horizontal government in the Church...
German cardinal Walter Kasper has been perhaps the most outspoken, telling the Italian daily La Repubblica before a media blackout was imposed that it was time for a "more horizontal government" to shake up the Church hierarchy.I must admit, I don't like some of the Cardinals. You know who else I don't like?
"The Curia must be revolutionised," Kasper said in the interview, adding: "As well as the word reform, there must be a second: transparency."
Cardinals like Kasper have called for the talks to last longer to give more time for discussions that could effectively set out an agenda for the new pope but Italian media reports say that many Italian cardinals are getting restless. - Cardinals eye Vatican reform


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Hackensack Dog Bites: The Basics
Created by FindLaw's team of legal writers and editors | Last reviewed August 17, 2017
This article has been written and reviewed for legal accuracy, clarity, and style by FindLaw's team of legal writers and attorneys and in accordance with our editorial standards.
The last updated date refers to the last time this article was reviewed by FindLaw or one of our contributing authors. We make every effort to keep our articles updated. For information regarding a specific legal issue affecting you, please contact an attorney in your area.
A dog bite can cause serious, painful injuries that leave lasting scars. We all love Spot, but sometimes Spot can bite. Dog bites are a common and serious problem in America. Young children and the elderly are particularly at risk. If you or a loved one has suffered a dog bite in Hackensack, you probably have numerous questions.
Hackensack dog owners are responsible for keeping their animals under control. In most cases, if a dog attacks another person, no matter if you're walking down Main Street or in someone's home, the owner is legally responsible for that attack.
Let FindLaw throw you a bone, so to speak. Here the basic lowdown on dog bites in Hackensack.
New Jersey Dog Bite Laws
New Jersey's dog bite laws places strict liability on dog owners for injuries caused by their animals -- even if the dog doesn't have a history of violent behavior. New Jersey is among the majority of U.S. states that makes a dog owner legally liable for all of the damages inflicted upon a dog bite victim, even if the dog has never previously exhibited the propensity to bite.
Can I Also Sue the Landlord for a New Jersey Dog Bite?
Maybe. If you were bitten at someone's house, you might be able to hold the landlord liable also. To hold a landlord liable a jury must determine that the dog had a vicious or dangerous trait or propensity and that the defendant, landlord, or property owner, knew, or in the process of reasonable care, should have known of the particular vicious or dangerous trait or propensity in the dog which caused the plaintiff's injuries. Here are some ways you can prove vicious, dangerous trait, or propensity in a dog:
- Animal control records;
- Police report records;
- Veterinarian records;
- Neighbors' statements;
- Admissions of the dog owner;
- Prior victim statements;
- Other visitors to the property;
- Hire a private investigator.
One-Bite Rule: Not in New Jersey
In many states dog owners will only be held accountable for a dog-bite if it the pooch has previously bitten someone. This is known as the "one bite" rule. New Jersey is not one of those states. So, as Tony Soprano or Mickey Blue eyes would say, "fuggedabout."
Report the Attack
Report the bite to the city of Hackensack right away. Tell the animal control official everything you know about the dog, including the owner's name and the address if you know it. If the dog is a stray, tell the animal control official what the dog looks like, where you saw it, whether you've seen the animal before, and in which direction the dog went.
Gather Evidence
If you are considering a lawsuit, you may want to consider talking to an experienced attorney. Some things to gather before speaking to an attorney are all the records regarding your attack, including animal control records, medical records, police reports, and any other records/reports regarding what happened. Also, take pictures of any injuries. It is easier to show a picture of an injury than to describe it verbally.
Recovering Damages for Your Injuries
Dog bite victims can recover damages for their injuries, but they'll have to file a lawsuit and prove:
- The defendant owned the dog;
- That dog bite another person;
- When the bite occurred, the victim was in a public place (such as a sidewalk or park) or legally on private property (such as the owner's home).
Note that the dog's owner may not be liable for a dog bite that occurs for trespassers with criminal intent. Also, victims whose own actions contributed to the attack may be found liable or partially liable.
If you have suffered a dog bite in Hackensack, you may be able to receive compensation for your injuries, emotional distress, lost wages and hospital and medical costs. An experienced local attorney may be able to provide you more information and answer questions specific to your circumstances.
Was this helpful?
You Don't Have To Solve This on Your Own – Get a Lawyer's Help
Meeting with a lawyer can help you understand your options and how to best protect your rights. Visit our attorney directory to find a lawyer near you who can help.
Next Steps: Search for a Local Attorney
Contact a qualified attorney.


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Cardi B has urged fans to show their support for female rappers who don't just rap about sex.
The 26-year-old took to social media to voice her support of female MCs who aren't just rapping about sex, after producer Jermaine Dupri slammed hip-hop for being filled with "strippers rapping".
Speaking in an interview with People Now, when asked how he feels about Cardi, Nicki Minaj and rising star Meghan Thee Stallion, Dupri was unimpressed, commenting: "For me, it's like strippers rapping and as far as rap goes I'm not getting who's the best."
In a video posted on Instagram on Thursday, however, Cardi addressed Dupri's comments, and called on fans to show the same support for the likes of Rapsody, Tierra Whack, Kamaiyah, and Chika that they do for her.
"There's a lot of female rappers who be rapping they ass off and don't be talking about their p**sy and don't be talking about getting down on dirty and y'all don't be supporting them," she said in response. "So don't blame that s**t on us, when y'all not the ones supporting them."
She added that the rappers who do talk about sex are the ones who get the best response from the audience.
"It seems that's what people want to hear," she continued. "When I did Be Careful people we're talking mad s**t in the beginning. If that's what people ain't trying to hear, then alright, I'm gonna go rap about my p**sy again."


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I sometimes want to go back
To the dim days behind,
To when I would wait beside the door
For you to come out and greet me with
Smoky kisses and warm arms,
Back to days when you would
Surprise me with mix tapes of
Music that I had never heard before
But would remember long after
You were gone and they were gone.
I still hear the music.
I still run across the songs on the radio.
I still remember your warm breath and
Your wet mouth and your deep eyes.
I miss the hope of futures intertwined,
The eagerness of walking across a
Frosted yard from my door to yours.
I miss all the brightness and beauty
Of the future I thought I had before me.
I want go back, but not for you--
I want to go back for me.
It's not you I miss, so much--
There are elements of you I miss
And elements of me with you I miss--
But when I grow quiet, and think of
Life in the receding "then,"
My heart reaches into that image to grasp
The dreams of the boy,
Not the hands of the girl.
But despite this smoky memory
And my unhealthy affection for
A thousand murky somewhens,
I am quick to remind myself
That the future is really still ahead of me,
And that only the players have changed.
So I, like my Irish bloodfolk,
Must press on to carve out
A new life in a new land,
Holding dearly to the memory
Of the Old World, while embracing
The endless possibility of the New.
Monday, August 09, 2004
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Subscribe to: Post Comments (Atom)


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Donald Trump has Republican majorities in both chambers of Congress — it's the first time since Barack Obama's first two years in office that the same party has controlled the U.S. Senate, the House and the White House. Trump's ability to enact his policies, therefore, will largely come down to how often GOP senators and representatives buck the president's agenda and, conversely, how often Democrats work with him. To help keep up with this, we'll be tracking how often members agree with Trump and how that compares with expectations.
We'll be using two primary measures for each member of Congress: the "Trump score" and "Trump plus-minus."
The Trump score is a simple percentage showing how often a senator or representative supports Trump's positions. To calculate it, we add the member's "yes" votes on bills that Trump supported and his or her "no" votes on bills that Trump opposed and then divide that by the total number of bills the member has voted on for which we know Trump's position.
We've set a few ground rules for how we're planning to count things:
- To determine Trump's position on bills and joint resolutions,1 we'll look for a clear statement of support or opposition made by him or by someone on his behalf. We'll generally stick to bills themselves, but we may include amendments when Trump makes a statement about them.2
- If there's a Senate vote requiring Vice President Mike Pence to break a tie and we don't know Trump's position on it, we'll assume that Trump supports it if Pence votes "yes" and opposes it if Pence votes "no."
- Votes in favor of Trump's Cabinet-level and Supreme Court nominations count as votes in support of him.
- We'll count any veto-override votes as bills that Trump opposes.
We're also calculating a metric that we're calling plus-minus. Plus-minus measures how frequently a member agrees with Trump compared with how frequently we would expect the member to, based on Trump's 2016 vote margin in the member's state or district. (The "predicted score" is calculated based on probit regression.) Put simply, we would expect a member in a district where Trump did well to be more in sync with him than a member in a district where Trump did poorly. As members vote on more bills, their predicted agreement score will change.
Previous administrations have taken clear positions on bills by issuing "statements of administration policy" through the Office of Management and Budget. We hope Trump continues this practice, but we don't know yet whether he will.3 In cases in which a statement of administration policy is available, we'll consider that the administration's stance. Barring such a statement, we'll ask the White House for the president's position on bills as they are scheduled for votes and look for media reports about Trump's stance. We'll always provide links to the source for Trump's position.
Without an explicit statement about a specific version of a bill, determining an administration's position can be difficult. Bills can change as they move through the legislative process, so a statement of support on a bill when it's introduced might not apply by the time it gets through both chambers of Congress. Also, just because a president supports an idea doesn't mean he supports a particular piece of legislation that purports to address that idea. A bill might not go far enough in addressing the issue, or it might go too far. It might address an issue in a way the president doesn't agree with. It might include provisions that an administration opposes alongside ones it supports. So there will unavoidably be some judgment calls to make; we intend to take a conservative approach, focusing on cases in which the Trump administration has provided fairly explicit guidance about its position.
As we publish this, the House and Senate have cast a combined 10 votes on measures for which we know Trump's position. That's not yet enough to make any sweeping statements about how members of Congress are reacting to Trump's presidency. The dashboard will update as more votes are recorded, and we'll post occasional stories about what patterns we're seeing, which members of Congress are voting with and against Trump the most, and other interesting findings.


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The perfect appreciation offers a special and qualitatively high-quality alternative to conventional photo prints for a beautiful snapshot of a photo on canvas. Photos from vacation, friends or family are particularly accentuated through a personalized photo canvas. Can be an order for a photo canvas at different providers in order. This can be done at a local photographers as well as over the Internet. To choose the way through a provider in the Internet one chooses his personal digital favorite photo and upload this on the appropriate Internet site of the provider.
Now you can decide later format, the quality of the screen, or a specific frame that. Teva Pharmaceutical Industries is full of insight into the issues. Is done, the selected photo on high quality canvas prints and personalized photo on canvas is finished. On request, the photo canvas is stretched in addition on an appropriate frame. For the covering of canvas on a sturdy wooden frame, be aware that about two or three Inch of the edge of the image are handled. It is therefore advantage that on the edge of the selected photos no important images or details are. Screens, the size used in quality and there are many differences of price classes. A general advantage of the photo canvas is the rugged surface, as well as the high water and light fastness.
There is also the possibility apart from a single image to print multiple images on a canvas and create a beautiful collage itself. Here you may order individually the images according to their own taste. One further possibility is, revealed three screens print to leave at the end of the desired Gesamtbilde reassembled. Almost limitless so in Vielseitgkeit motif, colour and format in a photo screen it.


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These two recipes for Smoothies with Grapes or Cherries include common fruit like apples for a nutrient packed drink to make in your own kitchen.
*FTC Disclosure: As an Amazon Associate I earn from qualifying purchases with no extra cost to you
*FTC Disclosure: As an Amazon Associate
I earn from qualifying purchases with no extra cost to you
No need to pay for costly smoothies at select shops and cafes, make your own smoothie for a fraction of the cost, and YOU control what goes into it!
All you need to make a smoothie at home is a blender or a food processor.
Recipe #1 - Apple and Grape Smoothie
2 apples
8 large size strawberries
1 cup green or red grapes
1 cup apple juice
Peel, core and chop the apple.
Add the prepared apple and all other ingredients to a blender or a food processor, and blend for about 30 - 40 seconds, until smooth.
Pour into chilled glasses, and serve immediately.
Serves 2.
Smoothie Tip
If you make smoothie drinks a lot, consider purchasing a mini-blender.
Some, for example the ones shown below (available from *Amazon.com), also include the cups that you can drink the smoothie from.
No need to pour the smoothie into another glass...and, much less clean-up.
Using a regular size blender requires more clean up, especially when making only one or two drinks.
Great gift idea too! I plan to buy one of these from my daughter who LOVES to make healthy smoothies!
Recipe #2 - Cherry Fruit Packed Smoothie
20 - 24 cherries
1 apple
1 banana
1 kiwi
1/2 cup blueberries
1/4 - 1/2 cup apple juice
Stone the cherries, and add them to a blender or a food processor.
Peel, core and chop the apple and add the pieces to the blender.
Slice the banana and add the pieces to the blender.
Peel, and chop the kiwi and add it to the blender as well.
Wash the blueberries, and add them to the blender.
Blend all ingredients, adding a splash of apple juice to achieve desired consistency.
Pour into chilled glasses, and serve immediately.
Serves 2.
See Also:
Apple Blueberry and Grape Smoothie
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Applesauce Maker
Pick from 12 Apple Pie Recipes
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I'm engaged in a handful web-development projects running on a LAMP stack. My present tool-set for inspecting and bugfixing is:
- the softwares built-in log-viewer and the like, and
- running "sudo tail -f /var/log/apache2/error.log" from the command-line, and
- "sudo tail -f /var/log/apache2/access.log"
That's pretty much what I've done on the server-side. I'm new to inspecting the server-side, so I'm quite happy with this minimal setup. Setting up scripts to automate things a bit is definitely a next action for me.
My question is: What tools (CLI/GUI) or command-line commands do you use to keep track, inspect and manage your log-files on your LAMP stack?


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Understanding The Widespread Regulation
The United States must adopt an immigration system that serves the national curiosity. Our on-campus clinics ( Immigration Law , Elder and Health Law , and Chapter ), referred to collectively as "Neighborhood Legal Services (CLS)" have been serving our community since 1974. The reality is that the impact on English courts is likely to be small. Small pockets of America could be nicknamed "Little Italy" or "Chinatown." Immigrants typically lived in poor areas of the town.
Apply crucial considering and drawback fixing abilities to resolve revenue tax points. Free File would have allowed the graduate pupil to keep away from all the charges and file her taxes totally free, however TurboTax upsold her with a promised tax break and by eradicating the shape she needed to say deductions on paid mortgage interest. Holmes's common-legislation paradigm reveals his indebtedness to Emerson, who availed himself of pragmatic superfluities of language to make sure the continuity and freshness of previous ideas in new contexts.
The detention comes amid a crackdown on undocumented immigrants. Money saved from having a lower tax fee helped pay for a surge in stock buybacks and dividend funds to shareholders. The body of law which includes both the unwritten law of England and the statutes handed before the settlement of the United States. Orphaned at a younger age and raised in humble beginnings, Jin beneficial properties favor with the Empress and makes her method into the royal court.
Parliament will sometimes also pass laws to bypass politically unwelcome consequences of judicial choices. The dividends paid to an Indonesian company's shareholder by its Indonesian subsidiary with a minimal of 25{e11480211e71893ef692afa9e04756f4b96917fe80d5414048d3af03471dcf4f} share possession are thought-about as Non-Taxable Earnings. Some courts, such as the Crown Court in England and Wales might have each trial and appellate jurisdictions.
Immediately, more than a hundred years on, as Singapore's flagship college, we proceed to be in service of nation and society. With the final ideas of common legislation adjudication as a background, the creator then examines and explains the particular modes of common legislation reasoning, comparable to reasoning from precedent, reasoning by analogy, drawing distinctions, and overruling.


text:
Zoya SecretZoya Secret is a Lebanese Brand, high quality and trendy for the modern Lebanese Lady.
Zoya'Secret for BEAUTY, Zoya'Secret for GLAMOUR.
Our collection of Trendy fashion keeps sophistication at ease, uniting luxury with contemporary ELEGANCE.
Founded in 2009 and driven by the quest for perfection, Zoya'Secret carries created for those who stop nowhere short of perfection. Zoya'Secret has grown rapidly from a young company to a market leading clothing manufacturer and exporter, serving the major local and international retailers.
It is our vision to be a reliable supplier and exporter by meeting the quality, cost, and delivery expectation.
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Zoya Secret - ZalkaZoya Secret is a Lebanese Brand, high quality and trendy for the modern Lebanese Lady.http://lebanesemall.com/listing/zoya-secret.htmlPosted by LibanMall.com on Wednesday, February 10, 2016


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Handmade Cycle Fenders Class @ Techshop
I'd first heard about Techshop through a mention on the Framebuilders list (thanks Alex!). It's been a life-long dream of mine to have access to a machine shop, so I was shocked to learn that Techshop has been active just a short drive away at their Menlo Park, California location since mid-2006, and I was only now discovering it! On their website I read about the large, well-equipped facility and about Techshop's origins. I envisioned a tidy, energetic place, bustling with creative activity. However, when I arrived for my class, I entered a mostly quiet, somewhat-shabby environment that was fairly devoid of people. As I pulled into the parking lot, I saw a guy ride up on a titanium fixed gear bike -- I instinctively knew he'd be in my class and that I'd be in good company. As I entered the building I was greeted by the receptionist, who (after guessing my name) informed me that there were only two students registered for the class, and had me complete and sign a waiver. I inquired about the usual class size, and learned that the maximum number of students per class was five -- I'd expected that it'd be three or four times that!
We met our instructor, who gave us a quick tour of the building's mostly-empty rooms. We first passed through the general project area -- a space containing about twelve large work tables with general-access parts/scrap storage shelving along one wall. Techshop members are encouraged to clean out the junk/scrap/excess from their home workshops and contribute to this community parts pool. If I remember correctly, there was only one individual working on a project when we passed through this area. At the opposite end of the large room is a lounge/kitchen area with a few scattered tables and chairs, and a bank of computers along one wall. I didn't ask, but presumably these PCs are for people to use when they visit Techshop -- I noticed several computer-graphics books next to one computer. Behind the lounge area is the main machine shop, featuring several milling machines, lathes, and other large machine tools. Most of these machines were silent: there were two guys working on a couple of the mills, but I couldn't see what they were making. Down a hallway, past some administrative offices, we saw the tool storage room where small hand tools, safety gear, and other equipment is housed. We stopped in at the paint room and saw their small vent-hood system as well as the powdercoating system. I asked how much it might cost to powdercoat something there, specifically wondering about paying for the powder I might use, and was told that small, one-off jobs in stocked colors were included in the normal Techshop membership fee -- but if I wanted to do a production run or needed special colors, I'd be responsible for covering that. Next door to the paint room is the laser-cutter room, where one person was engraving a photograph into a mirror to make a psuedo-three-diimensional portrait. The final room we visited was the metalworking and welding room, which is where our class took place. There were a few more people in this room finishing up a welding class, and they left shortly after our class started. One side of this area held MIG, TIG, and OA welding equipment plus a large computer-controlled plasma cutter; the other side of the room housed a sheet metal brake, cutting tools and a rotary stamping press, a work table, tools for bending, shrinking, and stretching sheet metal, and a small English wheel and an air-powered planishing hammer mounted on a shared pedestal. After my class was over, as I wandered around searching for the restrooms, I passed many more dark and empty rooms: a sewing room housing industrial sewing machines, a few rooms marked "Private" or "Project in progress", and a retail area with some books, small parts, and tools on display.
Our instructor started our class with a quick overview of the tools we'd use to make cycle fenders: delrin hammers and leather bags, the English wheel, the sheet-metal shrinker, and the planishing hammer. He used the power shear to cut some sheet aluminum into samples for us to work on, roughly 2x8 inches in size. To curve the leading and trailing edges of the fender, we used a scribe to trace around the bottom of a soup can and then cut the arc using metal shears. We gently filed the cut edges of the piece to debur them. Next we used the delrin forming hammer and the leather sand bag to rough in the compound curve. The spherical end of the hammer stretches the metal when struck against the bag, and the soft surfaces insure that no work-hardening of the metal takes place, which can lead to cracking during later forming stages. Once the compound curve is formed, the ridges and imperfections in the part are smoothed using the English wheel -- this tool has flat upper and curved lower wheels which you pass the piece between. The gap between the two wheels is adjusted by a large screw, which you tighten as you work the material back and forth through the tool. It's important to keep the part pressed against the curved lower wheel so the material adopts its shape. After the part was smoothed, we moved on to the shrinker tool to curve the sides of the fender inward even further. The shrinker has two sets of plier-like jaws which grasp the material and then squeeze together sideways incrementally, forming little ripples in the material. (The stretching tool, which we didn't use, does exactly the opposite -- the jaws clamp the material and then move apart). The final forming step was the air-powered planishing hammer, which works like a miniature jackhammer driving a flat hammer against a domed anvil, and imparts the characteristic dimpled appearance onto the material. The planishing hammer mainly smoothes the surface, although it also stretches, thins, and forms the material as well. The lower anvil can be swapped for other shapes to acheive different results and/or depending on the size of the part being formed. The air pressure driving the hammer can be adjusted, ours was set at 20-25psi depending on the thickness of the aluminum sheet. Finally I used a beading tool to roll the long edges of the fender inward, to simulate the shape of Berthoud fenders.
Although Techshop wasn't exactly what I'd expected, I had an enjoyable experience. I imagined a bustling hive of activity (what self-respecting DIY'er wouldn't want to play in a machine shop all weekend?!) but, perhaps because it was a Sunday afternoon, the facility was fairly empty and quiet, save for the occasional machining noise. The instruction I received was quite loose and informal -- I would've preferred something a bit more structured and comprehensive -- but given that it only cost $30 for nearly three hours of facetime it's a good bargain. I learned a lot about hand-fabricating bicycle fenders (and now have renewed appreciation for Honjos and Berthouds!) and I might attempt to make an actual set of fenders at some point (if I can find material to work with), although frankly given that you can buy a set of quality metal fenders for $40-50 these days, it's certainly not a good investment, time-wise. I definitely want to return to Techshop in the near future for more classes to learn the basics of TIG welding, using the Bridgeport mill and the lathes, and other exciting DIY topics!
Postscript for those in the SF-Bay area: I asked the instructor about local sources for aluminum sheet and other metals -- he recommended Metal Supermarket @ 2999 Spring Street in Redwood City, CA (650) 299-9856. From their website, it appears they have other locations throughout the USA and Canada as well. I'd never heard of them so I wanted to pass this along...
Update: Here's another source for many of the tools used in this class: http://www.eastwoodco.com. They have a video demonstrating the shrinker/stretcher tools (requires Quicktime).


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Louisiana's coastline is in a vast ongoing change. The Vision for the State, politically; must change as well.
Wednesday, December 16, 2009
Louisiana Attorney General takes Homer, La.-Bernard Monroe CaseClaiborne DA Recuses Office
The eighth annual Martin Luther King Day Noon Ecumenical Observance will be noon Monday in the Ruston Civic Center.
This service follows the annual Martin Luther King Unity March and parade that will start at 11 a.m. at Louisiana Tech's Thomas Assembly Center, where marchers will meet at 10:45 a.m. The event is coordinated by the office of multicultural affairs at Louisiana Tech and produced by a committee of students, faculty, staff and local residents. The keynote speaker will be the Rev. Carmelita Pope Freeman, regional community relations director for the U.S. Justice Department and an ordained elder in the CME 4th Episcopal District.
Grand Jury to hear Racially Charged Case| Homer investigation moves forward| "What other choice do we have"|
December 10, 2009
Monroe case sent to Attorney General
Stewart recuses office from shooting investigation Dees & Claiborne NAACP Reps
MICHELLE BATES, Editor
Claiborne Parish District Attorney Jonathan Stewart has recused his office from any further involvement in the February shooting death of 73-year-old Bernard Monroe Sr.
In a press conference held Wednesday, December 2, Stewart addressed the case, saying he was sending it to the Louisiana Attorney General's Office, citing conflicts of interest for his office.
"After the order of recusal is signed, my office will have no further involvement with this case," Stewart said, "other than to turn over the entire file and investigative materials to the attorney general, which will occur at some point in time next week."
He cited two reasons for bowing out. One, he said, is that both former Homer police officers involved in the case – Timon Cox and Joseph Henry – are witnesses in pending criminal cases, which have not been resolved. Second, he said it would put his office and the officers in a "difficult position."
Monroe was shot and killed by Cox on Friday, February 20, in the front yard of his home. According to police, the officers were pursuing Monroe's son, Sean. The foot pursuit ended in Monroe's front yard where Cox allegedly chased the younger Monroe out of the house.
Initial reports say Monroe was shot when he allegedly engaged the two officers with a loaded handgun. Witnesses, family members and friends say Monroe did not have a gun in his possession at the time of the shooting.
Stewart refused to answer any questions regarding what is in the final report turned in by the state police.
"I do not want to prejudice how the attorney general presents it, and I also do not want to prejudice anybody that might be on the grand jury," Stewart said.
Stewart said the attorney general's office will convene a grand jury from Claiborne Parish in January 2010 in order to make a decision on whether to pursue criminal charges or not.
"I have spoken with the attorney general several times over the last month, and he has agreed to give the case his personal attention," the district attorney said.
In the wake of the shooting, the Monroe family hired Southern Poverty Law Center heavyweight Morris Dees to represent them.
The Southern Poverty Law Center is a nonprofit organization, and was founded as a small civil rights law firm in 1971, according to their website, www.splcenter.com.
Along with Georgia Norton, Monroe's sister-in-law, Dees made it clear that the Monroe family wants to see justice.
"This family has suffered greatly to have their loved one shot to death in their presence, inside their house, by a police officer who had absolutely no legal rights to be in this home," Dees said. "We have been very patient – the lawyers, the family has been more than patient. At this point, we put our faith in the grand jury and this community, and we'll have to wait and see what happens. As the late Dr. Martin Luther King says, 'The moral arc of justice is long, but it bends towards fairness in the end,' and we hope that's what we'll see in this case."
Asked if a civil suit would be filed, he said they would wait and see.
"We're going to make that decision with the family and we'll be discussing what they ought to do," he said. "You can be assured that the facts of this case are going to come out, whether in a criminal case or in a civil case."
Homer Town Attorney Jim Colvin said, "We'll represent and defend the town as best we can, and we look forward to the conclusion to this investigation. As a citizen of this town and as town attorney, I look forward to the conclusion of this investigation. If there is a civil case, we'll do our best to represent the town's interest based on the facts revealed in the investigation to come."
Norton spoke on behalf of the family, saying that Monroe's widow is doing as well as can be expected.
"We're okay," she said, "and we're hoping for the same thing that our attorney is – that this be fair and justice is fairly done."
Terry Willis, communications director for the National Association for the Advancement of Colored People (NAACP), repeated her sentiments, saying he hopes the case is handled in a "very expeditious manner."
"We need this resolved so that our community can begin to heal and that justice will be served no matter what the outcome," Willis said.
When asked if he thought the case would go to trial, he said, "Hopefully not."
And if the officers are cleared of wrong doing?
"We'll just have to cross that bridge when we get to it, no matter the outcome," he responded. "This is a 'catch 22' for this community, for this department and our local government. We will have to settle and deal with the circumstances whatever they may be."
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Although in recent years much attention has been focused on developing and cataloging content, we now see a growing trend in developing and cataloging conceptual models and pathways within and across the subjects and disciplines of the Institute. Through engagement in this endeavor, OEIT intends to support this growing trend by providing systems and tools to our community.
Educational Need
The end goal of current MC3 efforts is the ability for a teacher or learner to search, browse and/or otherwise navigate educational resources based on the topics or educational objectives for a particular subject, discipline or field of study. From a teacher's perspective, MC3 is designed to facilitate the re-use of cross-disciplinary content in the preparation of course materials. For students, it is designed to allow for efficient navigation of the vast and growing collection of educational materials at MIT and elsewhere to help augment and deepen understanding.
Project Description
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While the architecture and tools of MC3 will be relevant and useful to the broadest range of educational environments, including both K-12 and Higher Education, it should be noted that MC3 does not strive to normalize or align the world of educational objectives into standards. There are currently projects underway to align educational standards, primarily in primary and secondary education. For instance, the CCSSO Common Core Standards project is doing this across a number of state school systems. The tools and architecture of MC3 is designed to work with these standardized models.
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Next Steps and the Design of MC3:
This project is designed to anticipate future needs beyond its immediate scope and beyond MIT, and therefore a number of architectural assumptions have been developed:
The initial MC3 service has been developed and is being tested with and applied to a number of current educational projects at MIT, including but not limited to:


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Rhytidectomy aka Facelift Video Presentation
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by Tyler
Hi, my name is Tyler. I was hoping that you could help answer some general questions for me about dating/marrying Ukrainian women so I can determine if Ukraine would be the best option for me compared to dating someone from another country. Feel free to answer whatever questions you can, however extensively you feel comfortable.
About Me:
I am 25 years old and am considering pursuing foreign dating in a couple of years (I have to pay off student loans first). I make around $40,000 per year, but my expendable income is around $15,000 per year. Is there a minimum income that you think is required in order to date someone from the Ukraine? I am not sure how much money an average Ukrainian woman would expect me to spend on her with my income. Currently, I live in a 1 bedroom apartment in a town of about 1,800 people (I have always been a person for small towns, although I am fine traveling to larger cities on occasion, or for work.) Do most Ukrainian women expect to live in cities or towns, or doesn't it matter much?
I consider myself kind, considerate, and more on the intellectual side. Generally, I am one for conversation about a variety of topics. I would consider myself somewhat romantic.
The following is what I am looking for in a partner. Please notify me if these requirements are realistic or not, and if not, which ones.
I am looking for someone who is kind, considerate, caring, loving, affectionate, honest, loyal, and has a sense of humor. I also want someone who knows how to disagree and resolve issues respectfully. Personally, I would take a woman who is a "6" or "7" on a physical attractiveness scale and is personable, emotionally stable, and loving than someone who is a "10" and is manipulative, condescending, etc
I am also looking for someone who is good with kids (I am expecting to start a family in the future). I have heard from a relative who has a friend whose son married someone from Russia that the Russian wife is very cold, stern, and unaffectionate towards her child. I have no idea if this is an individual behavior that the wife has or if it reflects a general trend in how Russian or Ukrainian women parent children. If you could tell me about what the general parenting style is in the Ukraine/Russia, I would appreciate it. I also am looking for someone who does not have any kids, but I remember you recommending on your website to try not to date someone very young without any kids because women who have kids are more likely to be "settled down". Is it very difficult to find someone without kids who is settled down and knows what she wants in a relationship?
I also would like to find someone who is not into partying and does not have a long history of partying and "being around the block" (I know this probably sounds derogatory, but I am having a difficult time expressing it in more "politically correct" terms). One of the problems that I have read about from some people who have dated women from Colombia, for instance, is that there is a cultural behavior of lying about personal history and actions, like number of romantic partners, educational background, careers, etc. (I am not trying to say that ALL people there behave like this). Is this kind of problem common in dating people from the Ukraine (lying about number of partners, actions, careers, etc.)? If this is so, are there ways to "filter" through those who are likely to have had a more "wild" or "undesirable" history than those who have been more on the conservative side? I don't want to sound like a probing jerk and ask a ton of questions to my possible future partner, but it would be nice to be able to have a general idea of her history, if possible. I would be glad to be open about my personal history to someone who I dated.
I would like someone who has a career or some career goals, as most American families cannot live off of one person's income in the U.S., unless the earner is a doctor, lawyer, etc. I would not have a problem with her working as a nurse, secretary, legal assistant, technician, etc., as long as her work can be separated from her home life, which I think more American women are having a difficult time doing with an attitude of "having it all" and managing the home like they manage some of their co-workers (to be fair, there are men that also do this). I know working outside the home may be adverse to what many Ukrainian women do, but I also would like to be realistic about maintaining a livable income between my spouse and I (and our future children). If a woman has a career, is her degree and/or career usually valid in the U.S. like it is in the Ukraine?
Have you heard of any agencies trying to convince/bribe women who are dating someone from the U.S. to continue dating other U.S. clients? I have heard that some agencies try to obligate a woman who is already dating a U.S. client to continue communicating and dating other people so the translators and agencies can continue to get paid money from more clients. Have you heard of this for any of the Ukrainian agencies you recommend on your site?
Relating to visiting the Ukraine, are there any precautions about "not drinking the water" or any other health practices to use? I know some countries have unsafe water, food, living conditions, etc., and I wasn't sure how safe the Ukraine is to visit at certain times or how safe their food/water is. Are the Ukrainian families welcoming to foreigners who date one of their family members?
Thank you for considering and answering my questions.
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text: Darren Binder, vice president and deputy general counsel of Bon Secours Health System, Inc., based in Marriottsville, MD, is co-founder of City Dogs Rescue, a volunteer-run nonprofit in Washington, DC. Why? "Rescue is stressful work, but it's enormously rewarding, and these dogs often have no one else to help them." Stats: Rescued more than 800 dogs from high-kill, overcrowded shelters since 2011. Pets: Grew up with Gidget, a black lab; now has a rescue dog, Cody, and two rescue cats. Website: citydogsrescuedc.org.


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OAKLAND — Garrett County officials on Thursday lifted the order that closed vacation rental properties, but with a number of restrictions and warnings.
Following Gov. Larry Hogan's Wednesday announcement of the first phase of his reopening plan, the county commissioners voted to amend their state of emergency declaration to allow the use of rental units effective immediately.
County Health Officer Bob Stephens also rescinded his March order on the rental units.
"Garrett County has been very blessed to have low numbers of infections, and we are in fact the lowest … in the state," Stephens told the commissioners. "We are all still at some risk. There will be new transmissions from time to time. Our goal in all of this is to limit the spread of COVID-19."
Commission Chairman Paul Edwards said the reopening of rental units comes with orders for both property owners/managers and the guests.
"The county, in consultation with the Garrett County health officer, have agreed that the order the health officer of March 27, 2020, closing all TVRU (transient vacation rental units) and vacation rental properties … is hereby rescinded, and that is subject to the provisions of the executive order and guidance of the office of legal counsel," Edwards announced.
To read the full article click here.


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Oppo is preparing to enter the Saudi market in November, announced the company, adding that it had started the implementation of its expansion plan early this year, and that it entered the European market in June.
The company is now operating in 33 countries, and plans to increase the scope of its operation, as well as obtain more market share.
Oppo also declared it is looking for an area near Tahrir Square in downtown Cairo to establish a new service centre, in addition to the current 10 Oppo service centres already operating in the country.
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