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Immunology in the XXI Century — Progress and Achievements
- Authors: Khaitov R.M.1
- Institute of Immunology, Federal Medical-Biological Agency of Russia
- Issue: Vol 4, No 3 (2012)
- Pages: 6-10
- Section: Forum
- URL: https://actanaturae.ru/2075-8251/article/view/10611
- DOI: https://doi.org/10.32607/20758251-2012-4-3-6-10
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Full Text
The awarding ceremony for the laureates of the Russian Federation National Award 2011 in the field of science and engineering was held in Moscow this summer. Two interviews with the laureates are published in the popular science section of this issue of Acta Naturae. Rakhim Musaevich Khaitov, who has been awarded for outstanding achievements in the fundamental and practical development of Russian immunology, talks about the current state of biomedicine.
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- Rakhim Musaevich, you have been working in immunology for 40 years now. How did it begin? - It all began in the Samarkand State Medical Institute. Back then, student scientific societies were very popular. I was a member of the radiobiology society. There was a boom in this field of science at that time; many researchers were interested in the effect radiation has on "living systems." I became interested in the effect of radiation on the immune system. The first books devoted to this subject were just starting to be published. One such book, Immunology of Acute Radiation Injury by R.V. Petrov, left a deep impression on me. When in the radiobiology student society, I started to simulate various immune reactions. I irradiated animals and made attempts at checking whether any antibodies against toxemia products emerged due to irradiation, similar to what occurs in other diseases. I understood back then that there was no way a vaccine against radiation sickness could be designed and that transplantation of bone marrow stem cells was the most adequate approach (the first studies devoted to stem cells were already being carried out). The major challenge was to devise the right method for selecting a donor and a re cipient based on immune response genes. I became so interested in the subject that I abandoned all other areas of interest and entirely focused on immunology. Unfortunately, there was no immunology in Samarkand in those days. It did not exist as an independent field of science in the USSR. It was a part of virology, microbiology, and infectious disease specialties; just a few hours within various courses and departments were devoted to this subject area. Then I decided to find an institute where I could carry out serious immunological research; so I set off for Moscow, the scientific center of the USSR. I visited a number of institutes; however, the themes of immunological research were either rather weak or did not sound interesting to me. Finally, I came to the Institute of Biophysics, Ministry of Health of the USSR. They housed the Laboratory of Immunology headed by the already mentioned Professor R.V. Petrov. At the time, he had just brought complex methods of chromosome analysis from England. Those methods were unknown in Russia at the time. The professor suggested that I implement those methods for 3 months. He hinted that if I succeed, I would be hired to work at the laboratory. It took me two weeks to develop them, so I was hired. In just a few months, I had the data published not only in leading journals of the Soviet Union, but in foreign journals, as well. - You have done great research. What can you say about the condition of the immune system in modern humans and that in humans in the beginning of the XX century? Are there any changes? - I believe that the immune systems in modern humans and humans who lived in the XIX-XX centuries are fundamentally the same. It is our knowledge and concepts relating to the immune system that have changed. For example, the term "immunity" already existed in the XIX century (the term was proposed by Louis Pasteur and originates from the Latin word "immunitas"); it denoted nonsusceptibility to infectious diseases. Later, in the end of the XIX century, people started to realize that it was not just some kind of abstract nonsusceptibility and that it was associated with particular things (specific proteins and antibodies recognizing bacteria and viruses) and with the cells killing these bacteria and viruses. The immune system remains the same; it is its response to the environment that changes. The system responds to new infections and new 6 | ACTA NATURAE | VOL. 4 № 3 (14) 2012 FORUM Rakhim Musaevich Khaitov, Director of the Institute of Immunology, Federal Medical-Biological Agency of Russia; Chairman of the Russian Association of Allergology and Clinical Immunology; member of the Council of the European Academy of Allergology and Clinical Immunology; leading expert with the Ministry of Health and Social Development of the Russian Federation for allergology and immunology problems, Academician of the RAS and RAMS, Doctor of Medical Sciences, Professor. Twice-Laureate of the National Award of the Russian Federation and the Russian Federation Government Award. antigens. There are only two systems in the human organism which possess memory and are capable of learning: the nervous and immune systems. Therefore, if an infection did not exist in the XVIII century - for example, the HIV or T-cell leukemia virus - it is natural that the immune system had no cells/ proteins that could recognize such foreign elements. These viruses exist today, so the immune system can recognize them. - An immunological map of Russia has been created on your initiative. Where and how is it used? - The immune status shows the state of the immune system in the complex. The immune system is very sophisticatedly organized; it includes central and peripheral organs and a large number of circulating cells, namely, T-lym-phocyte, B-lymphocyte, monocyte, and macrophage families. It is very important that all cells of the immune system interact with each other and are regulated by T cells (I call them "conductors of the immune system"). There are genes that conduct this immune "orchestra," and it is crucial that all the parameters of the immune system are normal in each person. So we raised the question as to whether the immune system parameters of individuals living in various regions of Russia are identical. For example, a person arrives from the polar region or comes down from the mountains. He can come to our institute and say: "I'm sick. Could you please check my immune system?" And what if the immune system parameters for the region he came from and the new location VOL. 4 № 3 (14) 2012 | ACTA NATURAE | 7 FORUM are different? In order to assess the immune status, we established about 120 clinical immunology laboratories in different regions of Russia. The parameters turned out to differ; but this is normal rather than a pathology. In some regions, the amount of T-lymphocytes is higher; in other regions, it is lower. Still other regions are characterized by the highest amount of B-lymphocytes. Of course, the differences are small, but they still exist. Thus, it is important to know the parameters of a specific region so that a person knows his/her normal immune status. - It is a known fact that it is easier to prevent a disease than to cure it. What measures are being taken to prevent immune system disorders? - There is a national immunization schedule, which includes N vaccines. Immunized children develop nonsusceptibility to these diseases (since the immune system possesses memory). This is one of the measures for fighting an infection. However, there can be genetic pathologies in the immune system; i.e., a child born has congenital disorders of the immune system. The immune system can also be suppressed by such factors as radiation, burns, injuries, a high level of stress, starvation, and exposure to harmful environmental factors. A permanently suppressed immune system results in the development of various disorders: autoimmune diseases, cancer, etc. The immune system is connected to all the other systems in the organism; that is why immune system disorders frequently cause pathologies in a number of other systems in the organism. Therefore, the immune status needs to be checked. - How can we check it? - Once you feel there is something wrong with your immune system, you need to take certain measures. What are the first signs? First of all, they include frequent respiratory tract diseases and other symptoms. In this case, you need to consult an immunologist to determine your immune status. If the immune status is suppressed, immunomodulatory agents are prescribed to reactivate it. We were able to pinpoint the regions where large population groups suffer from immunodeficiency. Preventive immunotherapy was carried out in these groups. It turned out that restoration of the immune system parameters abruptly reduces morbidity. - Rakhim Musaevich, can the use of immunomodulatory agents be harmful to the organism? - If your immune system status is fine, there is no need for immunomodulatory agents. One of my articles is even called I Have Never Taken Immunomodulators. Why? I check my immune status once a year. If it is fine, why should I use drugs? - You mean, there is no need to be overcautious? - There is no need if your immune status is normal, since it is fraught with autoimmune diseases, can cause allergic reactions, etc. Another situation is if a doctor (I mean not a self-taught doctor, but an immunologist) has diagnosed immune insufficiency. In this case, you need to take immunomodulatory drugs. - As for allergic diseases, why are so many people susceptible to them nowadays? And a lot of people acquire these diseases in their adulthood... - You are right. The frequency of allergic diseases has significantly increased recently. In the early XX century, only a negligible percentage of the population suffered from allergies, whereas today this figure is 25-30% in developed countries. There are regions in Russia where 15% (and even 30%) of the population suffer from allergies. These are extremely high numbers. If you remember, there were a large number of allergic diseases this spring. Spring came early and was warm, so the "green clouds" that emerged made people think about an environmental disaster. In fact, it was abundant blossoming of trees - birch, alder, and hazel trees. The pollen of these trees is responsible for the so-called "seasonal allergy." A lot of people with various symptoms of allergic diseases came for consultations to our institute. Some of them had never had any allergies prior to that. It was the "first wave"; the second wave has already started: other plants and grass are blossoming. There will also be a third wave in autumn. - And the number of people susceptible to allergies is increasing... - The point is that the surrounding world is changing. The number of infectious diseases used to be larger and the number of allergic ones smaller. The immune system used to be in a permanent fight against infections, but now we protect children against infections from early childhood. The position of the infections became vacant, so the immune system switched to allergens, which in fact are not infections at all. So apparently harmless proteins cause annoying allergic reactions, which sometimes can be very dangerous. In addition, a great number of triggers of allergy reactions have emerged, including pollutants, exhaust gases, and environmental factors. A number of them are not allergens, but they trigger the development of allergies. New drugs are constantly coming to market. Most of them are also allergens; therefore, drug allergy is one of the main problems nowadays. Food allergies are rather common: people used to eat traditional food, whereas now a lot of the new foodstuff is produced. In fact, there is no substance today 8 | ACTA NATURAE | VOL. 4 № 3 (14) 2012 FORUM that could be called completely allergy-free. - But some people develop an allergic reaction, whereas others do not... - Nobody knows why this is a selective process. Scientists know how an allergy develops, what causes it, and what the allergens are. They know the mechanisms of allergy development and how it can be blocked; however, it remains unclear why a person develops an allergy to ovalbumin, while another does not. I think that it is the genes that are responsible for this phenomenon. For example, one person carries genes encoding resistance to ovalbumin, whereas another carries a gene making him susceptible to this allergen and facilitating the development of an allergic reaction. It is possible that once these genes are identified, the allergy problem will be solved. - Your research group has designed antiallergy drugs. To what extent are you satisfied with the results? Do the drugs have any side effects? - Yes, antiallergy drugs, aller-gotropins, have been designed in our institute. These drugs exhibit much higher efficacy compared to the conventional allergens used to cure allergies. No specific side effects have been observed during clinical trials. We have forwarded these medications to the production stage and are awaiting registration and production. - When is that going to happen? - That depends on the enterprise that is responsible for processing the documents and obtaining the license for production and application. - What is the mechanism of action of these drugs? - First of all, our drugs inhibit the formation of "allergy antibodies." Second, they cause the secretion of protective antibodies, which block the allergic reactions. In other words, we used special molecules to affect different points within the mechanism of allergy development to finally design drugs that are practically significant. - How do they differ from existing antiallergic agents? - The already existing drugs -the first-, second-, and third-generation antihistamine agents -provide conditional treatment of allergies. They inhibit the allergic reaction; so it will return if you stop taking them. Allergen-specific immunotherapy is another type of treatment. What does it consist in? The causal allergen (i.e., the allergen causing a disease) is identified in the patient. The patient then receives the purified form of this allergen for a very prolonged period with the dose increasing gradually. The course lasts 2-3 months and needs to be repeated during several years. Complete recovery is possible in this case; however, this method is very complex, time-consuming, and fraught with complications. The drugs designed reduce therapy duration to two weeks and 15 injections; they also provide a more than twofold decrease in the need for pharmacotherapy. - To what extent will this therapy be affordable? - It is not up to us to decide. I do not think these medications will be more expensive than the allergens used for treatment today. -An anti-AIDS vaccine is being developed in your institute. What stage are the researchers at? - It actually is a rather complex problem. It is very difficult to design this vaccine, since the virus mutates quickly. So each patient may host a new variant of the virus. Therefore, many researchers believe that mining for a vaccine is a dead-end approach. However, not all scientists support this point of view. The fact is that even the AIDS virus has conserved regions that do not mutate; therefore, cer tain proteins or protein fragments in these regions remain intact. So there is a chance that these proteins can be used to design the vaccine. Scientists all over the world are working to solve this problem; however, almost no success has been achieved. Only one American-French group has had some results: two of their vaccines have provided a 35% reduction in morbidity. As for me, I believe that another approach should be used in designing the vaccine. The conserved antigens should be combined with immunostimulating agents; this will ensure robust immunity. Since a large number of people have already been infected, there should not only be preventive AIDS vaccines, but therapeutic ones, as well. HIV affects the immune system. Vaccines are inefficient in this case. Therefore, we hope that combination with immunomodulatory agents will ensure a therapeutic effect in infected people and probably even in people with AIDS. Our research group has designed a vaccine of this type; it is known as "Vi-chrepol." - What does it consist of? - We used genetic engineering techniques to design a chimeric protein. This protein contains fragments of various proteins found in the virus (both surface and inner ones, which do not undergo mutation). The protein alone causes no immunological reactions; i.e., it cannot be used as a vaccine. Therefore, it was bound to an immunos-timulating agent. This form of the protein had very strong immunos-timulating properties. A vast range of preclinical studies and phase I trials in volunteers have been carried out. We are now preparing for phase II trials, which will be more extensive. - A question emerges: are there any difficulties with clinical trials and recruiting volunteers? VOL. 4 № 3 (14) 2012 | ACTA NATURAE | 9 FORUM - The phase I trials need to be carried out only in healthy individuals to make sure that the vaccine is safe and indeed causes two forms of immune response: both antibodies and killers that destroy virus-infected cells are formed. Phase II trials will also be carried out in volunteers. Recruiting volunteers is a very difficult task. Healthy people often do not want to be vaccinated; nevertheless, there are people who are enthusiastic about vaccination (in particular, among the cohorts of sexual minorities). - What phase of clinical trials is carried out in infected individuals? - If phase II trials are successful, we will be allowed to proceed to the next phase and include infected people in trials. - If a vaccine is designed, which population groups will be the first to receive it? - How was smallpox defeated? Each person was vaccinated with an effective vaccine. There is an influenza vaccine; its effectiveness is lower than that of the smallpox vaccine but still rather high (7080%). Influenza epidemics still occur from time to time. Virus mutation is not the only reason. The fact is that only part of the population has been vaccinated; this includes the so-called "risk group," people who have higher chances to be infected: namely, schoolchildren, children attending kindergartens, doctors, teachers, and public transport employees. If every single person received the vaccine, influenza would presumably be defeated as well. Therefore, with allowance for the enormous scale of the epidemic, if an AIDS vaccine is eventually designed, it will certainly be optimal to vaccinate everyone. A lot of venereal diseases (syphilis and gonorrhea) are widespread today. They are all 100% curable; however, outbreaks of these diseases happen frequently. The reason is that there is no vaccine against these diseases. Only a vaccine is capable of globally defeating the disease. It is a significant fact that the number of human lives saved thanks to vaccination is much larger than the number saved by medicine as a whole. Vaccination has saved hundreds of millions of people. - Rakhim Musaevich, how would you estimate the time required to design the vaccine? - It is difficult to give a prognosis, since there will also be phases III and IV. The latent period of the AIDS virus may be several years (from 2 to 10-20 years). It is a very sophisticated infection, so it is almost impossible to give any prognoses. What we need to do is to keep working. - Is the research sufficiently supported by the Government? - The Government of the Russian Federation has adopted a very good resolution pertaining to the struggle against infectious diseases, including AIDS. Our program has received financial support, which allowed us to design the vaccine. Unfortunately, the resolution has already expired. - Is the level of Russian research in some areas superior to that of foreign research? - I would say that Russia is behind Western countries - the U.S., Western European countries, etc. - in terms of the general level of biomedicine. There have been some breakthroughs in Russia, as well. For example, we have done a lot in studying the immune status. Foreign researchers have not dealt with it. We have developed a large number of immunomodulatory agents (dozens agents), whereas only several agents have been designed by foreign researchers. A breakthrough has also been achieved in the area of AIDS vac cines: we were the first to develop vaccines with immunostimulators. There are no analogues of these vaccines in the world. In the international series AIDS Vaccine Blueprint, which annually reports on promising vaccines, our vaccine is mentioned among the top ten. In general, there has been a lot of interesting research done, not only in immunology, but in other fields of biomedicine, genetics, molecular genetics, and biochemistry, as well. - Has the level of AIDS morbidity increased over the past decade in Russia and in the world? - Unfortunately, it is increasing significantly in Russia. In some countries (such as the U.S., Canada, Western European countries, and Uganda), the increase in the rate of AIDS morbidity was stopped thanks to preventive measures. - As a research supervisor, can you make special mention of some of your students? - Quite a few scientists have defended their Candidate or Doctoral thesis papers under my guidance. Now many of them are professors; some of them are even members of Academies of Sciences. Many of my students have received Government and national awards. I do not want to mention any particular names. I respect all of them; they are all good people. If I single out a person or two, the others may be jealous. It is impolite. - What is your view about further developments in immunology? - We have a lot of ideas at our institute; in particular, ideas in the fields of molecular immunology and nanoimmunology. We have good financial support and excellent equipment. The only thing that is needed is an inflow of young researchers. · Interview by Maria Morozova
About the authors
R. M. KhaitovInstitute of Immunology, Federal Medical-Biological Agency of Russia
Author for correspondence.
Email: email@example.com
Russian Federation


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Today our Mortgage Broker in Manchester took part in Macmillan Coffee Morning, an event that the charity encourages others to engage in as a means to raise money for cancer support. We've taken part in many of these over the years as we try to help out the charity where we can. We call this the Broker Bake Off!
This year was one of the best yet, with some amazing food brought forward by our amazing employees.
These included;
All of these went down a treat with our staff and our building neighbours, who donated a solid amount for Macmillan Cancer Support.
We are very thankful for everyone that baked, donated, tasted and had fun during our coffee morning. We're all super full, but we can't wait for next year's Broker Bake Off here at Manchestermoneyman!

subset: commoncrawl


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Monday, July 30, 2018
Meet the nameless new girls
9 comments:
How 'bout Thelma and Louise for the twins?ReplyDelete
- Kipper7/30/18, 8:11 AM
More entertainment for Alex and Smooch! How about naming them after the girls in Little Women? Only names I can recall now are Amy, Beth and Jo.ReplyDelete
There were some awesome name suggestions on that linked post about naming the previous flock.ReplyDelete
I hadn't realized that you were down to just two and now one chicken. I'm glad Ten has some new companions.
Ha - my cats (and jrt) give the girls a WIDE berth - though Val has managed to maintain his #1 spot.ReplyDelete
- Laurie W.7/30/18, 11:40 AM
Just a big chicken...made my day! Cheers for Ten, getting some new roommates. The Americauna has beautiful feathers.ReplyDelete
Sorry to hear Peach died. I thought she was very pretty. I had never heard of an Americauna chicken until very recently when I started reading a series of books by Dawn Lee McKenna. The central character in the book owns one and it's name is Stoopid. Very funny chicken. Looking forward to seeing the colorful eggs!ReplyDelete
I'm happy Ten will have company and hope they all get along well. The two Barred Rocks look different to me - the one in the lower photo is more heavily feathered on her head. She has feathers completely around her ear, at least on her left side, and more feathers around her comb too. Kinda subtle differences, I suppose, if they're in a tussle over a lizard.ReplyDelete
We have a Barred Rock that my daughter named Barbie!ReplyDelete
I put colored zip ties on the leg of my chickens to tell them apart. While they grow you just have to make sure it doesn't get too tight.
- An American in Tokyo7/30/18, 5:53 PM
JCC knows when he is outnumbered! ha ha!ReplyDelete
I love how he replied to you when you said hi! Sooooooooooo cute!


text: Custom Designed KY Lake Waterfront With All The Bells And Whistles To Make Lake Living A Comfortable Experience. Upper Level Deck With A Large Lower Level Patio. 4 Bedrooms With 3 Full Baths And 2 Have Baths, Large 3 Car Garage, 4 Fireplaces Including One In Master, Hearth Room, Great Room and Family Room. Upper and Lower Level Kitchens, Pecan and Hickory Flooring, 2 Slip Covered Private Aluminum Dock, Cart Path To Water. Year Round Deep Water. Come See LAKESIDE MANOR! TODAY!NEW PICTURES COMING SOON!


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Purpose: To investigate the effects of real and simulated age-related changes in crystalline lens yellowing on Farnsworth-Munsell (FM) 100 hue performance. Methods: FM 100 hue total and partial error scores (PES) were measured in a group of younger (n = 10, mean age = 22.2 +/- 2.65 years) and a group of older (n = 10, mean age = 54.5 +/- 2.64 years) normal observers along with psychophysical estimates of crystalline lens optical density and pupil size. Three younger observers underwent repeated FM 100 hue testing under a variety of simulated age-related lens yellowing conditions, using filters with well-defined transmittance properties which attempted to mimic the real age-related lens yellowing changes of the older group. Results: FM 100 hue total and PES were significantly higher in the older age group compared with the younger group (p < 0.01). Lens density measures were significantly higher in the older age group compared with the young group (p < 0.01), but showed less scatter than individual FM 100 hue error scores. Simulated lens yellowing in the three younger observers, equivalent to the level of that of the older observers, did not affect any of their FM 100 hue total or PES. Conclusions: Simulation of age-related lens yellowing in younger observers has little effect on FM 100 hue error score. A variety of other factors such as pupil size, background illuminaton level, iris colour and macular pigment density may contribute to the age-related increase in FM 100 hue scores.
|Original language
|Pages (from-to)
|Ophthalmic and Physiological Optics
|Issue number
|Publication status
|Published (in print/issue) - Sept 2008


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Explosive new leaks explain why the UK government quietly rewrote its own code of conduct
Explosive new leaks may explain why the UK's Conservative-led government quietly rewrote its own Ministerial Code.
The government removed wording from the code that explicitly said ministers had a duty to comply with international law.
Within days of it trying to defend that decision in the High Court, the Intercept published an exposé. It revealed that Saudi Arabia had launched an airstrike against a family with nine children, which experts say shows "clear violations" of international law.
The UK government has staff working in Saudi Arabia's headquarters, where its targeting rooms are located. They are 'liaising' with the authoritarian kingdom on its bombing campaign in Yemen. At the time of writing, the Saudi-led coalition had just launched an airstrike near a public hospital, reportedly killing around 26 people.
Above international law?
The Gulf Center for Human Rights (GCHR) brought a case against Theresa May and Cabinet Office minister David Lidington over the code change in the High Court on 25 July. The rewrite, which occurred in 2015, removed certain references to a minister's duties. It originally read:
[there is an] overarching duty on ministers to comply with the law including international law and treaty obligations and to uphold the administration of justice and to protect the integrity of public life.
But the government shortened it to say there is only an:
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overarching duty on ministers to comply with the law and to protect the integrity of public life.
At the time, a Cabinet Office spokesperson said the changes brought it in line with the civil service code. They also claimed the "law" referenced in the revised version includes international law.
The High Court reached a verdict on 1 August. It ruled that ministers' "overarching" duty still includes compliance with international law and treaty obligations despite the government removing wording to that effect.
Strike first. Proof later.
The UK, along with the US, is complicit in the Yemen war. As well as having staff deployed for "liaison" in Saudi Arabia's headquarters, it's also providing "advice, information and assistance" to the country. Meanwhile, the UK government is arming Saudi Arabia to the back teeth. It's approved at least £4.6bn of arms sales to the country since it began bombing Yemen in 2015.
Reports of civilian casualities in the assault are common. But the Intercept's exposé gives a rare insight into why that's the case. Based on a US intelligence report seen by the outlet, it appears the Saudi military targeted a family, with nine children, on 14 May. Its drones had been surveilling the two tents the Maswadahs were living in close to a cliff in Saada prior to the attack.
According to the US report, the drones identified tents and "hot spots" – an indication people are present. But military officers watching the footage saw "no personnel or vehicles visible, nor any other intelligence information about the location".
The officer in charge, however, ordered the strike anyway – even though he didn't see the supposed target with his own eyes. The duty officers described the scene to him on the phone because he wasn't there. Exactly who carried out the strike is unknown, as the Saudi-led coalition includes multiple countries.
Thankfully, the strike was a failure. The bomb missed the family "by about 30 meters", according to the US report. Abdullah Maswadah and his family have since moved into caves, hoping that will be safer. He says:
The kids burst into tears when they hear the sound [of planes].
"Definitely a violation"
Clearly, seeing a couple of tents and indications of people present is not enough 'evidence' to justify an airstrike. As international law expert Ioannis Kalpouzos told the Intercept:
Beyond viewing the tents and the hot spots, if no intelligence was ordered to determine if these were military targets, then this is definitely a violation of the principle of precaution. This is the obligation to take all necessary measures to distinguish between civilians and combatants and to minimise incidental loss of civilian life
If the UK was a civilised country, this incident alone would lead to the suspension of arms sales to Saudi Arabia. It would also lead to the suspension of any member of government who has tied the country closer to Saudi Arabia and its murderous war.
But no. Instead, the UK government has been busy changing codes in a way that makes it less clear what culpability it has in atrocities abroad.
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The Canary doesn't have the budget of the corporate media. In fact, our income is over 1,000 times less than the Guardian's. What we do have is a radical agenda that disrupts power and amplifies marginalised communities. But we can only do this with our readers' support.
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You worked hard to get your credit score exactly where you want it to be. Now, you want to do everything you can to keep that number where it is. But what about inquiries? When financial institutions or others check out your credit score, won't it go down? The answer is both yes and no, as we examine the difference between hard and soft credit inquiries.
Hard Credit Inquiries
Hard credit inquiries are almost always performed by lenders and credit card companies, many utilizing services like CreditCheck Total. Any company that you have asked for a loan or a line of credit from is likely to make this inquiry, unless otherwise stated ("no credit check" is a common draw).
When a hard credit check is performed, it will affect your score, bringing it down by a few points. Hard inquiries can also stay on your credit report for a few years. All told, it truly won't have a massive impact on a good score, but if you're still wary of hard checks, here are a few tips to soften the blow.
First, you can be strict about credit cards you apply for. Don't fish around for lines of credit you're not sure you're qualified for. If you absolutely must submit multiple applications, do so within a short period of time. The reporting bureau will be able to detect that you're price shopping, and combine all of these inquiries.
It might also be worth it to look further into how many days you have to do this. The span of time during which you can get inquiries combined often depends on how large of a loan or credit line you're looking for.
Soft Credit Inquiries
Then we have the soft credit check, and chances are, you don't know who has performed them. However, you do know one person who's performed a soft check – it's you. When you peek at your own score on certain websites, this is a soft inquiry.
So, are you self-sabotaging? No, because soft inquiries do not bring your score down. In fact, anyone who has done a background check on you, including your employers, has made a soft credit inquiry.
Who else does soft checks? Insurance companies from whom you've requested a quote. Credit card companies that you already carry with, and those who want your business. Existing cardholders may have their credit soft checked to see if they qualify for special deals and programs, while new-to-you companies will tell you you've been "pre-qualified".
Pretty much anyone with a little data on you can perform that soft inquiry. Therefore, it's easy to see why they don't count against your score. If they did, anyone could just intentionally keep chipping away at another person's score.
How do you know if your next credit check will be hard or soft? Before getting a new insurance policy, job, or credit card, ask a representative directly what kind of inquiry is involved. In the meantime, check your credit report to see if any hard checks have been made that aren't associated with a loan or card you didn't apply for; there's a chance you could have it removed.


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Rolling Stone Readers Poll
(Rolling Stone (Australia))
Silverchair have polled extremely well in a readers survey recently
circulated in the Australian version of Rolling Stone magazine.
The results were released in the April edition of Rolling Stone (Australia) that hit the streets today (March 14th) but for all you silverchair fans worldwide we have the results below.
|Runners Up
|Artist Of The Year:
|Daniel Johns
|Nine Inch Nails, Korn
|Best Male Performer:
|Daniel Johns
|Jonathan Davis, Alex Lloyd
|Best Band:
|silverchair, Powderfinger
|Best Album:
|The Fragile (NIN)
|Neon Ballroom, Issues (Korn)
|Best Single:
|Falling Away From Me, Ana's Song
|Best Tour:
|Big Day Out
|Neon Ballroom, Americana/The Offspring
|Best Rock Artist:
|Powderfinger, Korn, Foo Fighters
|Best Dressed:
|Daniel Johns
|Comeback Of The Year:
|Red Hot Chilli Peppers
|Nine Inch Nails, silverchair
|Best Music Web Site:
|triplej.abc.net.au, Korn.com
Following is an example of what the interview holds.
Your song lyrics seem to contain such personal reflection and depth. Do you experience any difficulty in sharing them with other people, particularly if it's new material?
"Yes, I do initially because my lyrics expose parts of my life which I don't really talk about, but after a while I feel a sense of relief which is a gratifying part of writing."
What has been the most dramatic change either emotionally or towards your personality since silverchair became so successful?
"At first I was confused with the idea of fame, but I've learned to appreciate how lucky I am to be able to express myself for a living."
If you could change anything about this world's current situation, what would be your first decision? "For Neighbours to be played on weekends as well as weekdays."
[for our international fans Neighbours is an Australian soap opera that airs here week nights on commercial TV]
At the time of writing this post the Rolling Stone web site had info only on the March edition but I am assured the April edition will be up soon.
There is a link on the Australian Rolling Stone web site for subscriptions which may be useful for international people to obtain the magazine.


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Well, it's not really BLONDIE by the New Yorker's Roz Chast. It's actually an edition of RICHARD'S POOR ALMANAC drawn by good ol' Richard Thompson and reprinted for all of us in cyberland in his Comics Improved, Maybe blog entry.
His CUL DE SAC blog is a regular, funny read.
Sunday, February 10, 2008
BLONDIE by Roz Chast
Posted by Mike Lynch at 11:30 PM
Labels: comic strips
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About Us
Mission Statement
The mission of the biology department is to provide students with a solid foundation in both theoretical and laboratory aspects of biology and to prepare students for graduate studies or for specific career opportunities in education, research, medicine, allied health, and other professional scientific areas demanded by our global environment.
The biology department at UCO is one of the largest departments on campus.Students seeking careers as field or laboratory biologists, secondary science educators, or those who want to prepare for health care professions, will find opportunities available at UCO for their intellectual growth and career success.
A core curriculum designed to expose students to knowledge of life's diversity, cell biology, genetics, evolution, and ecology, ensures that students are prepared to face future challenges in biology and medicine.
Undergraduate and graduate research is facilitated by talented faculty members who hold terminal degrees in their areas of expertise. Faculty conduct laboratory and field research projects, many of which involve students. Students are encouraged to present their research to the scientific community.
The UCO biology department supports a biological field station, the Selman Living Laboratory (SLL), located in northwestern Oklahoma. The SLL provides educational and research opportunities for students and faculty in an array of natural environments, including bat caves.
Learning Objectives
Students graduating from the UCO biology program should be able to:
- Retain foundational knowledge from the core discipline areas and apply it to an understanding of the diversity and unity of life;
- Review and interpret scientific literature; develop well-reasoned, scientifically sound hypotheses; design experiments to test hypotheses; statistically analyze and interpret data, and communicate results in written and oral formats;
- Communicate biological information clearly, concisely, logically, and accurately to the general public, both orally and in writing; and,
- Function as knowledgeable citizens with an understanding of the role of scientists in society and offer ethical, well-reasoned arguments/solutions to societal concerns related to biology.
Evolution Statement
Science is the disciplined, logical search for knowledge about all aspects of the universe. It is based on the observation of natural phenomena and seeks to explain these natural phenomena through hypothesis testing and experimentation. A scientific hypothesis is a proposed explanation of a natural event. This hypothesis must be, above all else, testable and falsifiable. If an explanation does not meet these two requirements, it is not a scientific hypothesis. A scientific theory, in comparison to a hypothesis, is broader in scope and composed of a set of hypotheses that have been thoroughly tested. The term theory in the general public is synonymous with a guess. This is not so for a scientific theory. A scientific theory is supported by a large body of evidence and is continually tested and refined through the generation of new hypotheses. This is true for the theory of evolution.
Evolution is defined simply as the change in allele frequencies (genetic makeup) in a population through time. These changes can be small in scale, resulting for example in a population of bacteria becoming resistant to antibiotics, or large in scale, giving rise to a new species through a speciation event. The theory of evolution explains the mechanisms that lead to these changes. These mechanisms include non-random natural selection, random mutation events, random genetic drift, and gene flow. Each of these mechanisms has been and continues to be subjected to hypothesis testing. The theory is modified as new information is acquired through these tests; however, the overall theory of evolution continues to be upheld. Support for this theory comes from a variety of disciplines (e.g., paleontology, morphology, genetics, molecular biology, ecology, developmental biology, and biogeography). The theory of evolution is the unifying theory in biology and the fact of evolution is not controversial in the scientific community.


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TiVo for Fan TV
September 27, 2016
TiVo has announced that Fan TV, the next generation TV experience, will include new personalisation and discovery features across TV, tablet and mobile devices. Additionally, Fan TV will now be available on Apple TV and Roku, making it easier than ever for operators to expand their market reach.
The updated version of Fan TV will integrate personalised, contextual recommendations into the experience, as well as introduce a smart grid guide to enable users to rapidly find content within a familiar grid-based format. Fan TV will learn from user activity to guide discovery and provide intelligent and accurate recommendations to users seamlessly across live, VoD and OTT networks. The new smart grid guide delivers visual cues to alert users when programs on their WatchList show up in the broadcast schedule.
"TiVo strives to provide innovative discovery products and services for customers, enabling improved experiences for subscribers," said Michael Hawkey, senior vice president and general manager of the user experience business group at TiVo. "The updates to Fan TV will help subscribers find relevant content rapidly, while offering operators much needed flexibility across different networks and devices to mitigate trends toward unbundling and cord shaving."
Fan TV allows operators to deploy a next generation video service that leverages existing video delivery networks, including QAM, satellite or over the air, for linear video delivery.


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Now Use Android Devices with Extron AV Control Systems
- Public relations contact:
- Joe da Silva, Vice President of Marketing
- Extron
- E-mail: email@example.com
Anaheim, California (December 20, 2016) - Extron Electronics is pleased to announce the immediate availability of Extron Control for Android. Extron Control is an easy-to-use AV control system app that gives users complete access to Extron control systems directly from an iPad and now from Android devices. Simply tap the Extron Control icon and connect to your chosen room to experience seamless, highly-responsive control. Extron Control automatically loads the user interfaces present on many Extron control products without a lengthy setup and customization process. The familiar interfaces emulate the TouchLink Pro touchpanel, eBUS button panel, or MediaLink Plus controller in the room, and all button presses are kept in sync between the app and the Extron AV control device. Extron Control for Android is available for immediate download from Google Play.
"The Extron Control App became an instant success and remains a favorite app for people who want the convenience of AV room control from their iPad," says Casey Hall, Vice President of Sales and Marketing for Extron. "Now Extron Control for Android opens the doors to countless users who can enjoy the same BYOD freedom from an Android device."
Other powerful features include the ability to quickly add and switch between rooms, and auto-reconnect, which recalls the previous session even after the app is closed. Extron Control for Android supports all TouchLink Pro touchpanels, eBUS button panels, and MediaLink Plus controllers. Technicians will appreciate this new app, as it supplements the control of any room and provides easy access for troubleshooting.
For more information on the Extron Control App, please visit: www.extron.com/androidapp_pr


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At this point I was already setting the stage. I had One: Kicked up enough shit and not only uncovered a few enemies, I had stirred enough shit among the people I use to call family that word was bound to be getting around. Two: I made sure the word getting around was that I was letting out secrets, had an inside ear, and was making a show of paydays and the funds that I was building making it clear that I was not going to be down for long. Three: By kicking up a fuss and raising the paranoia level of my enemy I was making life hard on those who thought I was insignificant by pointing that paranoia at everyone around her. There would be no feed back, it was a blind plan to this day I honestly don't know if any of it was even required. My ex wife had already sent her new errand boy to constantly harass my sister via emails aimed at trying to coerce a location out of her. The only one who knew my actual location though had been my brother. The next phase of the plan had already started and that was trying to see who was actually on my side, since I had found enough enemies and to set up everyone else for the biggest fuck you, yet. They wanted to spew righteousness and this, that and the other, but in truth they were just Junior High School clique and I was going to show them that. This was to One: Piss them off enough to further get the rumor mill flowing and Two: Show them that a persons position is not always an accurate indicator of their true strength.
July 17th
It's a pickle no doubt about it, the truth is I'm stable and making income, so there really is no way of knowing what's smokescreen and what isn't, no way to tell if I'm cooking hot dogs on a campfire laughing my ass off even as I write the most hateful sounding shit. But whichever the case, it does make you think, that has ever been the blessing to my curse. There will come a day I either get bored or get funded enough to leave this place and no longer have a reason to piss on it, until that day I will continue to give merit to what earns it AND serve anyone, meaning anyone and to anyone at ALLLLLLL!!!!! 😀 LOL < This was put up with a link to the video for Sweeney Todds "Have a little Priest" Yes I have a fucked up sense of humor, I also wanted to keep everyone confused as to what to expect from me and when, whether I was strong or weak. Hard for an enemy to fight back especially when those enemies are cowards when they are not really sure what it is they are getting into.
Well that turned out better than I thought. hmmmm It's balanced enough. < Another quiz, this one pertaining to how good/evil you are. I got 43% good 57% evil neutral force.
DM: 70% evil: Troublemaker. I disagree, though. I don't make trouble; I am trouble. Note the subtle difference.
Shayne: Give me a couple more months, I'll get there. < A lot of truth is spoken in jest. 😀 I did get there, when the strength I found to overcome would clash once more with petty vindictiveness.
😀 And remember kids if you THINK half the shit I say is just to get attention. 😀 Well that would just be kinda pointless wouldn't it? I mean obviously you read it in order to have that thought in the first fucking place, which leads me to believe that you were always going to for whatever reason you may conjure up to feel better about it. 😀
Love, guttersnipe. < This post was like a gift that just kept on giving. I would use it many times to come in the future just to remind those who looked for trouble that they were going to find it, but then why anyone would LOOK for trouble and then blame the person who delivered is far beyond me. The reaction this got was priceless as no one could rightfully retort without making an ass of themselves. In chess that is called a forked attack which is simply placing a piece in just the right spot between two targets so that the opponent has no option but to choose which sacrifice to make. What this caused was an escalation in what I called the switch board effect. I would post and then suddenly my chat list would light up with the little green dots of people coming and going. It would eventually get to where I didn't even see the flashing green dots, I just heard in my mind the inevitable phrase being cycled around. "Can you believe what that little motherfucker just wrote?"
RN: Am I missing something?
Shayne: I actually have read the Art of War. Sometimes what I say is a matter of beating the ground to draw out the snakes. Sometimes it's to appear strong when weak or weak when strong ( That ones a bit tricky, follow it to the letter and you're predictable, appear as both…well then no enemy would know what to think you are, but insane 😀 and who wants to fuck with that? Especially when I have already displayed that I think ahead, consider my post from May 6, now I had hoped that it would be a deterrent but instead I had to use it to expose a terrible truth.) Sometimes I just want to show people something about themselves and as I am LEARNING, there is no better TEACHER of that than adversity. Sometimes It pays to remind people that it is like a finger pointing away to the moon, DO NOT concentrate on the finger or you will miss all that heavenly glory. 😉
July 19th
One of the most important lessons I have taken from my whole ordeal is a greater understanding of the truth that in this world where only the STRONG SURVIVE, those who beg for mercy are those too WEAK to deserve it…….Just keep in mind, for me the personal is just a bonus, it's really only business.
RN: Learn well and learn quickly. Looks like weather due to change for the worst by Sept-Oct. this winter will surpass last winter I'm afraid. You need to know- but I hated to break the news to you. Gotta find you a place asap
RN: Can you make out the maps and dates? < He had sent a couple weather prediction maps for the coming months. Some had expected the winter to be really bad.
Shayne: Providing I'm not back in my cage by then anyway, that is already in the works I've been all over the damn place putting many things in motion both in forward movement and back up in case my case goes foul. I get the maps, least ways enough to see like me, it's as cold as the cold wind blows. 😀
RN: Expect 20-30 days below -10
Shayne: Shit, if I'm lucky enough to get the Not Guilty nod, I should be in a place by mid Sept, sooner possibly, my stack is growing and I have a couple other options other than the job that can help it do so even faster.
RN: Gambles are just that. Stay on the real road. Pays off faster in long run.
So earlier I said fuck it like, I'm gonna sign up on one o' these online dating sites. I don't have a suitable picture on this phone, but for my tag line I put "Yeah, you Hitler enough for me." 30 Minutes later I already had 56 profile views, 15 flirts, 12 messages. It's a strange fuckin world we live in. Ha ha
DN: I signed up for one once and it said I had no matches
Shayne: If my "success " so far is any indication I would say you won and I lost. 😀 I just bullshitted it, I meet crazy just fuckin fine on my own, hence the whole thing I keep going back to about the eco hut in the desert and changing my name to Ben. Believe me I still have a scar from a ring I've not worn in almost a full year, then there is every other crazy bitch I've encountered from the one who disappeared on me for a year only to come back with someone else's kid, when I was still living at home JUST graduated. One during my marriage that was a psycho and wouldn't leave me the fuck alone when I worked for CAMC and a myriad of others…..man relationships are WAY fuckin over rated. < I have not seen many examples to dissuade me from this point of view and have in fact…. well, only half joked about the next time I get involved with someone, writing to girls in mental institutions so that I could at least control the TYPE of crazy that got attracted to me the next go round. Yeah considering how the next 10 months would pan out I would say that was an EPIC FAIL on my part, I should've started writing to those institutions sooner. 😀
DN: I'll just make one and make my name Adolf Stalin. Really fuck with people that way
Shayne: LOL Hell yeah. You know I think the biggest fuckin regret most people who know me have, is leaving my ass out here to entertain myself. That went south sooo damn fast, and it's all because I'm an asshole.
Shayne: Oh and just to clarify, the CAMC bit was NOT an affair it was just a psychopath who would not leave my ass alone. Why did I not report it, that's the rub, I did, but you try being the ONLY guy in an office full of women and see how serious that shit gets taken. < I have very distinct views when it comes to shit like this, but then you be on the receiving end of a line like. " You remind me so much of my ex husband."……. Yeah that's a seriously weird ass fucking thing to say with glazed eyes and a goofy ass grin on your face. Never had much luck with women at least not here anyway. Who knows if writing to the mental institutions doesn't pan out I might shoot for one of those mail order bride services. Either way it really can't get much worse than a bitch trying to get me either locked up or killed.
And the time of the hanger ons is almost up. Go watch Jerry Springer for your fix. It only gets WORSE and more VENOMOUS from here.< Another chance for them run for the hills………. No one took it.
July 20th
What? You think I'm throwing a White Trash Party here or something? 😀 Here's your sign.
Just in case there were some who missed the last post, or maybe if there was some sort of language barrier. You know, it's always best if you are going to be an asshole to people to always offer them an out, even if they don't take it they can never say you weren't being fair enough to give them the choice. My big prank was set and I was about to start building for it. If any had come to me in the interest of straightening things, they would have got a pass, if any had left they would not have been there to see what was coming in the first place. Those who stayed… Well I think the message here was rather non ambiguous. FIX IT OR FUCK OFF.
In a good mood this evening, so I'm gonna take a minute just to deliver a temporary ( Well partial reprieve anyway)
Tonight I focus on my REAL enemy, the State. If you take a look below you will see three pictures, the first is a page from my discovery a.k.a the prosecutions case against me. It is part of the police report from my arrest. In the paragraph you may notice that it claims that the post contained photographs. This made no damn sense to me because I added no photos to that post. I found from the psyche evaluation that they were referring to my profile picture which is the second photo below. This photo was used to profile my ass as a potential "terroristic threat"
Now looking at photos 2 and 3 what do you notice they have in common? A little cross promotion maybe, between a convention and a theater that I was a part of for nearly five years. IRONIC is a word that comes to mind that the very picture that got me labeled the bad guy in the eyes of the law was DIRECTLY linked to the volunteer work I was doing. Ain't that about a motherfucker? 😀 Try to be the fucking good guy just to get boned by it. Regardless I have that going for me as there is at least one or two members or more likely former members of the "family " that would be willing to vouch for my involvement.
This is but a small piece to the reason I may seem…..a little more crass this past little over a year, then I might have seemed in the times prior to. I wasn't shitting when I said I paid a price for the work I did, 8 days worth, with another one to three years plus 6 months for that copy computer charge the grand jury tacked to it as a possibility. Still in Purgatory, still all in my fucking face, dampening any Goddamn ray of hope from any victory I gain in my current predicament.
I would bet, you would crack too, just a little. It's not that hateful darkness doesn't seem so bad, it's just the result looks the same from down here. Be thankful you aren't me, if you're not facing what I am from where I am, as nigh singlehandedly as I am. For tonight I am thankful for us all, that it didn't happen to a person worse or more breakable than me.
Goodnight. < Okay they would not leave, now lets see which ones of those who stayed can be swayed by truth. This ladies and gentlemen and many other examples both seen and experienced personally is why I have such distaste for the bleeding heart Care Bears of the world. Some of us know better, some of us realize that change has to be fought for. Now there are two ways you can fight for that change. You can be the type of person who would go through with what I was accused of and change will happen, suddenly, from bad to worse.The shit storm mainstream media has made of the examples of people who have fought for change in this fashion and the inevitable over reaction caused by the fear it invokes has proven that fact time and again. I choose a different way. The pen is mightier than the sword approach or rather the pen as the sword approach. and many may not agree with my method any more than they agree with the former, all I can say to that is show me a world where "Being the change you want to see in the world" does not lead to what happened to me and I will concede my point. Interesting side note I would go on to actually stay true to my word and help volunteer for the event a little over a week after being released from jail on bond.
July 21st
You ever wanna be the person that causes that "aww man" moment? LOL I'm just a mean cocksucker I know. LOL I'll fix it shortly, promise. < I was, I am, and I lied after careful consideration of how things had panned out. You see the Burly Q had just hit 1000 likes and they were just so excited when they announced, thing is, I was still one of them, at least until I brought them back to 999. 😀 I really was going to fix it, it was just such a petty little move, but then I had to ask myself the real question, What kind of message did it send giving support to those incapable of returning it in any real fashion?
Actually after thought, I'm done with silent voices. < This would generate a rift with another who it had absolutely nothing to do with. Another example of ebb and flow. a once long time friend and "Brother" ( See it isn't always the bitches I duke it out with, sometimes it's the faithful lap dog puppies as well.) Fuck it, he wanted to be that quick to accept exile without even coming to me to see if it had anything to do with him. He can get served with the fucking rest of them. Par for the course.
Now, now, I just rectified a little inequity. If there is just give and no take, then I am the same idiot who got themselves in this mess in the first place and…..well just blow my fucking brains out if I ever get that stupid again.< The girls got a little miffed over the 999 thing. 😀
July 22nd
Peace is a lie
There is only passion
Through passion, I gain strength.
Through strength, I gain power.
Through power, I gain victory
Through victory, my chains are broken
Peace is a lie
There is only passion
Through passion, I gain strength
Through strength, I gain power
Through power, I gain victory
Through victory, my chains are broken
Peace is a lie
There is only passion
Through passion, I gain strength
Through strength, I gain power
Through power, I gain victory
Through victory, my chains are broken
Whether struggling with our first steps in infancy, recovering from an injury, standing for a purpose, overcoming a bad habit protecting what is ours EVERYTHING we are in life is defined by CONFLICT great and small, within and without. When we forget this, we STAGNATE in a life and world where CHANGE occurs with or without our consent. Ever being FALSE FATES PUPPETS and only half of who we are, until the day none of our escapes can keep REGRET from making us wonder why we never felt COMPLETE and then we face, with or without our consent, another CONFLICT, with DESPAIR. < PM, tiny dancer, was struck rather hard by this one. This was NOT a direct assault either, in truth it really was a sort of self reflection given my situation and all the years I had spent being my wife's little bitch, but hey….if the shoe fits. If the mantra, written in very "All work and no play" The Shining format, looks familiar to some of you geeks like me out there that's because it is the code of the Sith. See where I'm going with this? The reactions when I finally brought my little prank to fruition was quite hilarious. I will get to that in the next piece. The final piece of July… You know because if I'm going to tell the part of the story called Henceforth You Will Be Known As DARTH VENOMOUS, it really should come in three parts…..Shouldn't it? 😀


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The consumer protection council has disclosed that it has ordered redress up to the tune of N2.5 Billion for consumers in 2016.
This includes refunds and compensation in the resolution of complaints on unsatisfactory services and products.
Director general of the council made this known at the presentation of their annual report to the media and public in Lagos.
The DG added disclosed in the report that the organisation deployed the social intervention strategy in the satellite television services, food and beverage with particular reference to the beer industry, banking, hospitality, aviation and electricity sectors.


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The positive reviews for Enochian Magic In Theory are already rolling in:
"Students of the Western Esoteric Tradition are often presented with an "either/or" approach to Enochian Magic—they are told that they must choose between either the Dee Purist tradition or the Golden Dawn tradition because "one is right and the other is wrong." In Enochian Magic in Theory author Dean F. Wilson takes a refreshingly ecumenical approach, presenting the Enochian system from various viewpoints and removing the unfortunate partisanship that has too often entered into the discussion. Written from the perspective of someone who has considerable experience with Enochian, Wilson's text is reader-friendly and filled with valuable illustrations that will help students better understand this complex subject. We wholeheartedly recommend Enochian Magic in Theory to anyone, beginner or Adept, who seeks a well-rounded, well-researched book on Enochian theurgy."
— Charles "Chic" Cicero and Sandra "Tabatha" CiceroChief Adepts of the Hermetic Order of the Golden Dawnauthors of The Golden Dawn Enochian Skrying Tarot


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Point Grey is one of Vancouver's older neighbourhoods, with many long-time residents. The area is known for two of the city's popular beaches, Jericho Beach and Spanish Banks. Both beaches are great for watching the sunset over English Bay and the mountains. Point Grey Village serves as the area's shopping district, where many independently owned businesses contribute to a village-like atmosphere. Some of the city's most expensive homes are located in Point Grey. The boundary runs along English Bay to the north, W. 16th Ave. to the south and between the University of British Columbia and Kitsilano.
If you're looking to buy or sell in Point Grey, give me a call today!
Listed by Luxmore Realty.
Listed by Royal Pacific Realty Corp..
Listed by Rennie & Associates Realty Ltd..
Listed by One Percent Realty Ltd..
Listed by Pospischil Realty Group.
Listed by Amex Broadway West Realty.
Brought to you by your friendly REALTORS® through the MLS® System, courtesy of BrixWork for Realtors for your convenience.
Disclaimer: This representation is based in whole or in part on data generated by the Chilliwack & District Real Estate Board, Fraser Valley Real Estate Board or Real Estate Board of Greater Vancouver which assumes no responsibility for its accuracy.


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Yesterday I emailed our subscribers asking what they wanted answers to and any issues they were having. One of the primary themes we saw was people hadn't started yet, and worse they didn't know how to get started.
All I can say is don't overthink it.
I'll get onto how much you need to get started in a second but first we need to talk about over-analysis-paraylysis. I can't remember who came up with that phrase but its one of my favourites in the business & investing world. This is simply where an individual takes no action because they are paralysed by the amount of information out there. This is very common and I am personally guilty of this too. A phrase instead to live by is below.
So now that we have that covered, let's get back to the primary question at hand. How much do I need to start trading? That's an extremely broad question that depends on 3 things:
- How much knowledge of trading do you have?
- What is your long term aim? Full time trader? Part time? Just for fun?
- How much time can you dedicate to it?
If you cannot dedicate at least 10 hours a week to it then you won't make money. Between 10-30 hours = Part time trader, which I believe can make about 20-50% per year on their money and 40+ hours = full time = 50%+ yearly ROI.
But that still doesn't answer our question.
So this is a general rule: You want to start with the MAXIMUM amount you can afford to lose. I also don't recommend anything under $10,000. The reason? Well let's do the maths. Assuming you make 50% a year and DON'T withdraw any along the way. This $10k becomes $400k in 10 years and 15 years? Well that's $3 million, this is assuming you don't withdraw and you earn 50% per year. This is of course not easy and you will have to have the knowledge and systems in place BEFORE getting started. But back to our original point it is a lot better to take some action than to take none at all. Even if that's demo accounts, which I hate, that is still better than nothing.
There are other types of action
Making trades is not the only type of "action". Instead you can begin researching new potentially profitable theories, brush up on support and resistance training, earn money to increase your starting capital or back-testing systems or strategies you think may have been profitable in the past. Although past results DO NOT equal future results, there is a lot of proof that strategies tend to perform the same if set-up correctly.
Hope this clears this up. Remember to subscribe and comment below and if you haven't done so yet check out our starter trader 10,000 word guide and our free ebook.
Tom is the owner of Elite Forex Trading. A website that provides beginner tips, trainings, reviews and strategies to help newbies get started making money in the forex markets.


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The Olympics Parade of Nation-y Peoples
The father of Nodar Kumaritashvili, the young Georgian luger who died the day before the start of the Olympics, was himself a Soviet Union luger. His father was likely, during those broadcasts, called "Russian."
Now there is no more Soviet Union and the officials insinuate "those athletes from those small countries haven't trained enough" and say his death was due to "human error." But "these athletes from these countries" with large coaching staffs are also saying that the course is just too fast. I refer you to Howard Bryant's on-line column: "With athletes' fears out in open, Olympic powers-that-be must listen."
So while this idea of "independence" and nationhood is celebrated, along with the idea of the end of oppressive regimes, such free little nations are implicitly warned: "Be careful what you wish for" and "Welcome to the free world where the playing field is very uneven." I also refer you to Bryant's "Haves and have-nots share the same stage."
I understand the prideful feeling of "the little nation that could." My Estonian father used to point out all the Estonian last names competing for the USSR. They are names that sound and look Finnish, but are usually shorter because they are nouns, standing for everyday things like "hill" or "flower," names grabbed up in a mandatory "sur-naming" movement: a moment of "freedom" for the Estonian serfs that was of course tied to the ability to conduct a census and implement taxation. Welcome to your nationhood. Now pay up.
My all-time favorite gymnast, Olga Korbut, is not Russian, I have just learned. But when I was young I somehow understood that Ludmilla Tourischeva, USSR gymnast, could look Asian and be called "Russian"; she was born in Chechnya, I have since found out. When the iron curtain was in place, stories of Bela Karolyi forcing the Romanian gymnasts to push cars up hills as part of their training seemed believable. So when Karolyi came to the States we were all a little surprised by the bear hugs he gave his gymnasts. He got "nation-y" right before our eyes.
Tanith Belbin was Canadian but became Canadian-American when she started competing with her American partner Ben Agosto, who is Jewish and Puerto Rican, born in Chicago. The Canadian ice-dancers, Tessa Virtue and Scott Moir, who won the gold, train in Michigan. The Turkish figure skater Tugba Karademir trains in Canada and performs to Turkish music. The camera showed us her parents in the audience. "At first they had to work menial jobs; now her mother works for Lockhead Martin." American figure skater Mirai Nagasu's parents are Japanese. The Japanese woman who skates with a Russian partner moved to Russia and gave up her Japanese citizenship because she wanted to train with the best. They got silver. The US figure skater Johnny Weir trains with a Russian coach and loves everything Russian, including Yevgeny Plushenko's mullet hairdo, and so he signifies on Plushenko—he has an even better version of the haircut and speaks Russian. His costumes have pink tassels and lace up, signifying on the corset, and he plays to the crowd in a flirty way that makes him appear very femme. More than one person I have talked to believes that his scores suffer because he has taken the sport of men's figure skating to its conclusion—"are they all gay?" Question for further research: are Gay Games competitors divided up by nation as well?
South Korea's Kim Yu-Na trains in Canada and skates to music from James Bond. Occasionally she does saucy moves and holds her hands together as if she's pointing a gun, signifying on those famous Bond film introductions of curvy women in silhouette. Which reminds me that I once read an article on gender and sport that said that the camera frames the female figure skaters much more closely than the male skaters. During the short program, female figure skaters must show their flexibility, hold their leg up while grabbing their skate blade, and reveal quite a lot. Dick Button, the femme, enthusiastic, and New Jersey-born gold medalist skater of '48 and '52, who is often a fire-side chat guest of Bob Costas, has said he is not a fan of this move.
There's the Canadian ski-cross competitor Chris del Bosco who grew up in Colorado but his father is Canadian. Joannie Rochette, Canadian figure skater whose mother died in the days leading up to the competition, is Quebecois. But the Canadian anthem appears to mostly be sung in English. If you are Swiss your name can be Carlo or Heinz or Jacque.
And there is a Jamaican ski-cross skier Errol Kerr who was born in New York. He failed to advance to the finals of his sport which lead Jonny Moseley—freestyle skiing legend and inventor "the dinner roll" trick—to comment, sadly: "there will be no cool running this time." But competing in Vancouver 2010 is "the snow leopard," a nickname given to Kwame Nkrumah-Acheampong, alpine skier from Ghana who, according to The Washington Post "started racing just six years ago after taking up a job as a receptionist at a dry ski slope in Milton Keynes, England." Other temperature inversions exist. There is Estonian cross-country skier Kristina Smigun who won a silver medal, lives in Florida, and says she hardly ever trains. By the way, Smigun is not a very "Estonian" name—she is the daughter of Anatoli Smigun, one of many ethnic Russians who are also Estonian.
If you have been watching the Olympics and following all these "nation-y" identity constructions, you might now conclude that the playing of the "Star Spangled Banner" is a rather absurd National Hockey League tradition. The Russian ice hockey team features the Washington Capitals star Alex Ovechkin who is in an NHL scoring competition with Pittsburg Penguin's star Sidney Crosby who is Canadian. Players you never guessed are Canadian are Canadian. Players you guessed were Canadian are from the US. But "North America" is a term now being used to designate the "togetherness" of the US and Canada in order to celebrate the victory of the Canadian ice-dancing pair, as in "they are the first North Americans to win a gold medal in this sport."
There was controversy when the Russian ice-dancing pair wanted to wear Australian aboriginal costumes and dance to "tribal" music. Upon arriving in Vancouver, it was reported that they had a meeting with some First Nations officials, gifts were exchanged, and after the first compulsory dance, the pair sat in the kiss and cry area with "native" blankets slung over their shoulders to signify an understanding of some sort. This same ice-dancing pair used controversial bondage ropes as part of their costumes for their last dance. He grabbed her ropes often in order to lift her, suspend her, and swing her around. Because they also appeared to have the Mona Lisa airbrushed on to their costumes, I thought the dance signified on The Da Vinci Code, but I might be wrong. The US ice-dancing pair Davis and White signified on Indian-ness in one of their dances: "that coy sideways glance" and certain yogic hand positions were the unifying moves, we were told, of the entire dance. We were also told that unlike the Russians, "these costumes are authentic" and "this dance has been downloaded all over the world, but do you know where it's most popular? In India!" The nation-y parade continued when the Israeli pair Roman and Alexandra Zaretsky, who train in New Jersey, danced to the Jewish folk song Hava Nagila, a song written in 1918, and signifying their Jewish-ness, even though, or perhaps because one can be Israeli and not Jewish. And then there was the French pair who came out as cowboys and I admit that her cowboy boot skates were amazing. As they danced to country music—a music not at all the domain of just cowboys—I began to catalogue all I had seen in just two hours and it appeared as if there was no "self" or "other" or "authentic" left.
At the closing ceremonies, the athletes walk in to the stadium all mixed up, when just two weeks prior, they marched in under "their" flag, proving that the Olympic spirit is schizophrenic: We are different! We are the same! It is enough to make one feel "nation-y" all over—an Olympic feeling far more innocent than the blood that is shed over the imaginary known as "nation."


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Cricket Australia have made the bold decision to BAN WAGs from the player's hotel rooms for the current Cricket World Cup and Ashes series. If you like Australia for the Cricket World Cup with their WAGless influence this summer, then you may as well take up an offer from bet365.
The Aussies are second-favourites for the trophy but I personally like Pakistan at a bigger price, despite their recent loss to the West Indies.
Away from the betting however, the Australian federation have made the bold decision to ban all the players' wives and girlfriends from their hotel rooms during the majority of the tournament, in an attempt to concentrate the minds of their key members.
The team manager Gavin Dovey has claimed that the idea is to find some 'balance', but admits that it would be 'ridiculous' to ban family time for the entirety of the competition.
Team manager Gavin Dovey said: "We want to get the balance right with the best outcome for everyone. There are a lot of challenges but what we've tried to work out when we think it's important for the group to be on their own, knuckle down and focus on the task.
"Then you look at when it's important to be around your families.
"We can't go a whole World Cup and Ashes and not have families as a big part of it. That would be ridiculous over such a long period of time."
Former star Ian Healy revealed that similar stances have been used in the past, highlighting the need for focus.
Australian cricket legend Ian Healy added: "They weren't allowed on tour until after the series had been won.
"Your mind needs to be completely focused on it. Cricket is a sport that requires complete concentration."
The All Blacks banned WAGs from their hotel rooms during the Rugby World Cup in 2007. The All Blacks manager at the time, Darren Shand claimed: "Every player is different in how they prepare.
"It's pretty common knowledge that most sporting teams at home do the best, so we try to create an environment like that when we are away. It's up to individuals to make the best decisions; we have to trust them."
Will Cricket Australia pay the price for separating the players from their families? Do we all need a little bit more WAGs around?


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Hi there!
Kayt here, founder of The Naked Beauty Box and Blog. I wanted to be honest with you about why I started The Naked Beauty Brand. In order to get there, I need to give you a little history on my skincare journey.
As a teenager I was one of the lucky few who have great skin and never worried about acne….How many people can say they were that lucky! Went off to college to study Engineering and gained the freshman 15, or in my case it was the freshman 45. I never thought much of my weight gain. I wasn't playing basketball anymore and eating like crap and getting the occasional zit…. I thought this was due to eating junk food and not working out. I am 6'0 and at the beginning of college I weighed 175 and by the end of college I was maintaining 220 as my new normal.
Fast forward a few years and I am 22 working as an engineer, living in the middle of nowhere America….nearest city to me is 3.5 hours away. I started putting on more weight, but this time my weight gain wasn't gradual. I put on 55lbs in less than a year and I started to get cystic acne, and my periods were to the point of my husband (at the time we were dating) rushing me to the hospital because I was losing too much blood…..That was probably one of the craziest and scariest moments of my life. I spent the next year seeing ten specialists and doctors who "couldn't find anything wrong with me". It went as far as having a doctor tell me that it was all in my head. Before you think…it was a man….nope, a female doctor told me I was making my symptoms up and nothing was wrong. After excepting that maybe what was happening was all in my head, I began to except it as my new normal. I still wanted to get my acne under control and decided I would go see a dermatologist for my cystic acne. I was self conscience about having acne because I do not wear make up to work. While my husband was finishing his degree in Butte, MT I decided to visit a dermatologist there and within 30 minutes of me sitting in her office talking about my concerns she began asking me questions dating back to before I ever started getting periods. Once my appointment was over, she gave the name of a Nurse Practitioner who specializes in PCOS (Poly Cystic Ovary Syndrome) and she was almost certain that was my issue. The Dermatologist still proscribed me a topical ointment, but then called the NP's office and sent me straight to her that day. I spent the next month working with the NP and going through my medical history and the blood work she ordered. I finally had an answer after over a year of being told nothing was wrong with me. At 24 I was offically diagnosed with PCOS.
Flash forward 4 years…..At 28 I still have PCOS and acne flare ups but I know how to manage it through diet and a really GREAT skin care routine!
I was a long time subscriber of IPSY, for almost 10 years. But as I matured, mind and skin, I preferred quality skin care products and less makeup products….Don't get me wrong, IPSY is a great company and they have started offering some skin care products. But it wasn't what I would have liked to see every month. I started researching options and wasn't finding any skin care services that allowed me to try great products for a decent price.
Still living 3.5 hours from the nearest city and not a fan of buying skin care products online and wasting my money on something that doesn't work….I can't tell you how much money I have thrown down the toilet in the past four years on skin care. I started brainstorming and researching that I wasn't the only one who was having the same issues. So I decided that I wanted to bring other people like me quality skin care products from top and up-and-coming brands with out wasting their money…..I already did that for us hahaha
The objective of The Naked Beauty Box is to bring a range of products to you to try that you would have never known about or would never thought about spending the money on. I mean the majority of us are not going to spend $22 on one sheet mask, but would honestly really love to try something that expensive without paying full price for it….Am I right?? Expensive brands/products are not the only thing you will find in The Naked Beauty Box. You will also see products that are affordable and are still of great quality. With my brand, I want to create and experience that everyone of all walks of life will enjoy.


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Joanne Wilson is an art collector. She spent 5 hours at the Armory Show last week looking at art and, eventually, even buying a few things. We usually hear a lot from dealers at art fairs but rarely do we get a sense of what a buyer sees, thinks and does. Fortunately, Wilson is a sometimes blogger too (her husband is New York's most visible venture capitalist.) Here she shows what caught her eye [we liked that Sultan too] and gives some of her thoughts too.
Still Recovering from the Armory Show (Gotham Gal)


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I think I killed Roy Scheider.
As I was watching Lake Placid 2, I commented how it made the original (which I wasn't a big fan of either, though Brendan Gleeson was pretty awesome, as usual) look like Jaws in comparison. Then a few hours later I went to my PC and saw that Scheider had died a few hours earlier. Sorry.Of course, the movie is supposed to be as funny as it is scary – but it doesn't work in that matter either. Cloris Leachman replaces Betty White (she plays the original character's sister) and her wicked old lady routine is supposed to amuse, but it doesn't at all, and neither does anyone else. The only actual laugh I got out of the entire film is when some EPA guy picks up his dead friend's leg and waves it around in a "Do you believe me NOW!" type moment. 1 laugh, 0 scares, 88 minutes. You do the math (if I provided enough information to solve the problem).
Suffice to say, Lake Placid 2 is a really fucking terrible movie, even by Sci-Fi standards. It's not even goofy fun like the original or the average 'original' Sci-Fi film. Headless Horseman may not have been a classic, but I was at least entertained and the production value was high. This can't even manage that, as (painfully obvious/bad) CG is not only used for every single shot of the damn croc, but even a goddamn seaplane (and they actually manage to make the plane look faker than the crocodile!). At least the CG editor knew how bad the plane looked, since after it docks it promptly disappears from every shot it should be in until they actually use it again. Nice work. And while they actually do a decent job of pretending that Bulgaria is Maine, the over abundance of Bulgarian cast members with thick Bulgarian accents sort of ruins the façade.
But abysmally bad production value on every level isn't what sinks this film. What really brings it down (besides blatantly copying the character types from the original – Bill Pullman and Brendan Gleeson are combined into John Schneider, Sam McMurray plays an Oliver Platt clone, and some broad I've never heard of is the poor substitute for Bridget Fonda) is how nonchalant everyone is when they see this gigantic crocodile bearing down on them. Granted, there was nothing there (there's a hilarious moment where a guy swings a stick, and we even hear it connect, but the stick doesn't hit anywhere near the CG croc), and the damn thing's size changes from shot to shot, but for Christ's sake, ACT! At one point they simply sit there and watch the croc swim up and then demolish the boat they are sitting on; I don't think they even bother to scream. Everyone is so matter of fact during the attack scenes that you can almost forget that they are in danger at all. If they aren't scared (or fuck, even ENGAGED), why the hell should I be?
Sadly, the only frightening things in the film are Schneider's hair:
And this dude's bizarre chest hair patterns:
Another annoyance is the film's ending. After Schneider delivers a record three (THREE!) one-liners to the crocodile and finally kills it, the movie drags for another 3-4 minutes as we learn that Schneider and the EPA chick are going to go out for dinner, and that his son is going to hook up with the girl who lives next door. Guess what, whoever wrote this crap – no one gives a rat's ass about a single non-crocodile character in this film. Once the last croc is dead, the movie is over. If you're going to keep it going, at least add in a little set up for the 3rd film, however unwanted it may be.
The disc also has 3 featurettes of equal value to the film itself (so, none whatsoever). One is a fast forwarded version of the film that only plays the parts with tits and gore, but since these moments are so botched those aren't worth watching either; you'll want to fast forward this version as well. The other two are just more or less clip reels. Thanks for wasting even more of my time, FOX (or Sony, whoever had the final say in this joint release). The only worthwhile thing on the entire disc is a spot for some Sam Jackson/Josh Hartnett movie that has 1.2 seconds of my beloved Rachel Nichols contained within; though that's hardly enough to warrant even renting this goddamn abomination.
What say you?


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Passport Maintenance: Keeping Up With Your Passport
By Sarah V. Hines, on October 5, 2018
Planning an international trip can be stressful. There's often flight information, hotels, transportation and safety to concern yourself with. Many countries also require visas before you board your flight, adding another round of paperwork before the trip begins. With so many pieces to put into place, many people forget the single most important documents for international travel: their valid passport.
Working for a company that expedites passports, I can't begin to tell you how many people have run into issues and errors with this particular document. New travelers are often surprised that they need a passport for travel into Canada or Mexico. Even seasoned travelers are caught by surprise at recent changes to required validity of their passports for some countries.
Whether you think you're good to go or you're unsure, below are common issues that are catching travelers by surprise, and what you can do to prepare.
Passports Are Needed for Any International Travel
While there are some cruise lines that will allow you to travel with an I.D. and birth certificate, all other international travel (and other cruise lines) will require a valid passport.
The process for the new passport can be tedious. You must fill out your application and provide your proof of citizenship (birth certificate or naturalization certificate) and have the documents sealed by a local acceptance agent at a courthouse or a post office before you send your documents in. The routine process can take 6-8 weeks on average, though many people have reported the process sometimes lasting for as long as 12 weeks. The Department of State has a 3-4 week expediting service, and companies such as A.P.V.I. can get the documents through in 2 weeks or less. Both routes will accrue extra costs to process the application, so if you're planning international travel and do not hold a valid passport, it's best to start the process as early as possible.
Lost Passports Must Be Replaced
People often ask if they can just show a copy of their passport for travel if they've lost the physical book. The answer is a very emphatic, 'no.' Passports must be physically present during the time of boarding, as the passport must be scanned and any visas needed must be verified. There is no way to look up a lost passport in any system.
Any person that has lost a passport must follow the new passport process and include a Statement Regarding a Lost or Stolen Passport (DS-64). As with a new passport, the process can be lengthy, so it's best to plan ahead. It's not uncommon that people discover their passport has been lost or stolen before their trip. In that case, companies like A.P.V.I. are a life-saver for getting the passport through The Department of State and back to you before your trip, as well as assisting if there are any visas that will need replaced.
Passports Must Be Valid
You cannot travel on an expired passport at any time. While this problem pops up with many people, the good news is that, so long as the passport is a 10-year passport that has expired within the last five years, the applicant is eligible for renewal. A renewal process is very easy, as you will only need your old passport and your application with your photo and government fees, and you will not need to have the documents sealed ahead of time (though the processing time remains the same as all passport processes).
There is a catch to this; parents traveling with a minor should know that any passport issued before the age of 16 is a child passport and cannot be renewed. If the child is still under 16 when the passport expires, the parents listed on the birth certificate will be required to follow the same process as the first time they applied and will need to turn in both the expired passport and the birth certificate during the process. If the child is 16 years old or older, they will be filing for their first 10-year passport and will sign the application in front of the acceptance agent themselves. They will also be required to turn in their expired passport, which can count as their proof of citizenship if they are unable to locate a birth certificate.
Some Countries Have Validity Laws
Even when your passport is valid, it may not be valid for travel into certain countries. Mexico requires that your passport be valid for six months after your departure from the country in order to even enter. In Europe, many countries have either a three- or six-month validity rule. When traveling, it's best to check the requirements for the country that you're visiting. If you find that your passport does not have enough validity remaining, you will need to have the passport renewed. There is no problem with renewing your passport up to 2 years before it expires.
Some Countries Require Blank Pages
If you travel frequently to a country that stamps your entry visa in your passport upon arrival, you will need to make sure that you have blank pages to enter and exit the next time. It's advised to have two blank visa pages side by side (not including the endorsement pages in the back of the book), and it's a good idea to renew the passport after your trip if you are down to your last two. While countries such as Canada do not stamp your passport and won't bar you entrance, countries such as Italy or Spain may not allow you to enter if you don't have the pages to stamp.
Requirements for visas also vary from country to country, and the types of visas needed (tourist, business, etc) will require different paperwork submitted. While this part of traveling seems tedious, it is unquestionably the most crucial. Passport processes can take a long time to get through The Department of State, so if you're trying to leave within two weeks, it's best to go through an expediting company such as A.P.V.I. to have the documents back before your trip. Once your passport is set, you will be much closer to finalizing your trip and looking forward to the travel.
Mohd Minhajuddin
Recently had a chance to get my Visa work done through APVI, amazing service and very professional, will highly recommend for any Visa needs.Great job!!


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Far Southeast Side
The righteous is concerned for the rights of the poor. - Proverbs 24:7
This neighborhood was first a settlement to farmers and fishermen, who gave it the name "Ainsworth." Prospectors saw promise for this area, believing it would become a connecting point for outside shipping routes due to its location on the Calumet River. Therefore, people bought up the land around 1883, including many Irish Catholics.
The convenience of the railroad also helped this area's early growth. After the Great Fire of 1871, industry began making its home in South Chicago, migrating further south. The steel, grain, railroad and lumber industries grew in this area as companies such as South Works of North Chicago Rolling Mill Company, which opened in 1880.
At this time, almost half the population of South Chicago was African American and another forty percent Latino. In 1992 the South Works steel mill was shutdown, many people lost jobs, and local business was in great decline. Since then urban planners and some industry have moved in, but progress continues to be slow.
information courtesy of Moody Publishers
"Chicago Neighborhood Prayer Guide" by Dr. John Fuder with Elizabeth Koenig
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