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Student welcome events
IDP Education's support does not finish once you arrive in your new country.
If you are studying in Australia, IDP Education hosts regular events to welcome students to their new country.
The events, which take place twice a year, are held in five states across Australia. The events range from cruises on the iconic Sydney Harbour through to in-office meet-and-greet morning teas.
The events also provide an opportunity for students to meet IDP Education's team of Australian-based counsellors, who are available to provide support to students throughout their Australian studies.
Take a look at some of the images from our recent events.
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Like most websites IDP Education Pty Ltd uses cookies, in order to deliver a personalised, responsive service and to improve the website. We remember and store information about how you use the website. This is done using simple text files called cookies which sit on your computer. These cookies are completely safe and secure and will never contain any sensitive information.


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Six Beautiful Jars for Canning, Gift-Giving, or Simply Admiring
If you're trying to make good use of the summer's bounty of produce, you're probably going to end up doing some canning or preserving. (Of course, the best place to start is our Canning Basics Guide.)
And if you plan to give any of your jams, jellies, pickles, and more as gifts, you're going to need some of these beautiful canning jars that are completely gift-worthy.
6 Beautiful Canning Jars
1. Spring Green Wide Mouth Ball Jars, $15 for six from Cooking.com: Ball jars are definitely the base line for canning jars. And as far as colors go, you're most likely to see blue ones, which is exactly why this spring green set caught our eye.
2. & 3. Frosted Glass Straight Sided Jars, $33 per case & Clear Glass Oval Hexagon Jars, $13-$33 per case both from SKS Bottle: If you want something a bit out of the ordinary, shop at a bulk or industrial supplier. Both of these styles are sold in cases of 12 or 24 jars. We also love that they are perfectly primed for custom labels.
4. Kilner Clip Top Jars, $25 for 4 from Williams-Sonoma: Clip top jars are great because they can be so much easier to open. Plus, we'll always happily use them to store rice, beans, or quinoa once the preserves or pickles are all used up.
5. Quattro Stagioni Canning Jars, $2.50-$4 each from The Container Store: Think of these as the Ball jar's glam cousin. They are similarly designed, but are Italian (quattro stagioni means the four seasons), have an embossed design of a beehive and fresh produce, and they come topped with gold lids.
6. 7.4 oz Weck Jar Set, $18 for four from Terrain: We couldn't talk about beautiful canning jars and not include some from Weck. The German glassware with the rubber gasket and separate clips is the gold standard for beautiful jars.
Now for the real question: Do you expect your friends to return those fancy jars or are they part of the gift?

subset: commoncrawl


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Raspberry Pi fans,
The WDLabs team has learned a great deal from engaging you and designing products for the DIY community. We continue to investigate emerging ideas, however, the time has come for our engineers to explore new areas. The WDLabs products for the Raspberry Pi ecosystem are now available only on a limited basis and will be discontinued. WDLabs engineering support will also be discontinued on the WDLabs community, although the WDLabs community forum will still be available for forum member interaction. Our understanding of and appreciation for the creative Raspberry Pi community is highly valued by Western Digital and may resurface in the future.
We thank each and every one of you for your support these past three years.


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The two names on the ballot Tuesday for Bartow City Commission should be familiar to most voters in the city.
BARTOW | The two names on the ballot Tuesday for Bartow City Commission should be familiar to most voters in the city.
City Commissioner Adrian Jackson hopes to win a third three-year term on the city's governing board. Hoping to unseat him is perennial challenger Gerald J. Cochran, in his 20th effort to win election to the City Commission.
This isn't the first time the two have faced off in a city election. Three years ago, Jackson defeated Cochran with 74 percent of the vote. Jackson took 790 votes to Cochran's 273.
When asked what he wanted to change in the city, Cochran said he thought it was time to start over.
"I'm tired of the whole mess up there," said Cochran, a 74-year-old retired phosphate worker.
He said city employees are slacking on the job, the city's utility billing system needs to be overhauled and commissioners need to slash their own monthly salaries from $530 to $50 as a cost-saving measure.
Cochran, a longtime critic of City Hall, said he's also opposed to limiting speakers to five minutes when they address the City Commission during public meetings.
Jackson, 64, a retired airline pilot and admiral in the Navy Reserve, said he wants to see the city complete some ongoing projects that he's supported during his term in office.
Jackson has been a strong advocate of the city's recent strategic planning program, which identifies the city's goals and challenges and outlines steps to achieve those goals.
He has said this will be his last term on the five-member board.
Jackson holds Seat 3 on the commission, representing the city's northern district. It's one of three district seats, which require those commissioners to reside in the districts they represent. The remaining two seats are at-large, meaning they can live anywhere in the city.
Commissioners in Bartow are elected to three-year terms and also serve as the Bartow Airport Authority, which oversees policy at the city-owned airport and adjacent industrial park. Board members receive $250 a month for their service on the Airport Authority.


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Florence, S.C. - In their opening game, Coker plated one run in the first inning and put the game out of reach with four runs in the fourth inning en route to a 6-0 win.
Coker finished the game with six runs on five hits and committed no errors. Slippery Rock scored no runs on three hits and committed four errors in the game.
Shelly Catlett (Orangeburg, SC) (7-4) earned the on the mound, while Anna Oswald (Lexington, SC) had two home runs for the Lady Cobras.
Coker continues their play at the Patriot Invitational on Saturday, play Indiana University of Pennsylvania at 11:00 a.m., followed y Francis Marion at 1:00 p.m. All games are being played at Freedom Florence in Florence, S.C.


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Tuesday brought brutal cold to Stark County and thawed Browns writer Steve Doerschuk's memory of scraping ice off a window to see a famous playoff game. How cold was it? One player's frozen mustache broke off.
I'll be sledding up to New Jersey for the Super Bowl in a few weeks. All one can do is laugh about what it will be like if the weather is like Tuesday's.
Those of us who attended the "Red Right 88" game in Cleveland still are laughing.
Many will say it stands as the coldest day of our lives.
The weather was just like Tuesday's. It was a January 33 years ago.
Quarterback Brian Sipe was the hottest thing going. The wind chill was minus-33.
Browns fans had suffered long enough. It had been an eternity, more than a decade, since the Super Bowl began, and by golly, the Browns were going.
The Browns' first playoff game in eight years was against Oakland. I went as a young writer accompanying Sports Editor Bob Stewart.
The paper had two writer credentials. Stew's was in the heated press box atop the south side of Municipal Stadium. Mine was in the unheated baseball press box.
Kicker Don Cockroft, now a Stark County resident, spent the afternoon in the great outdoors.
From Don's book "The 1980 Kardiac Kids" ...
n Cornerback Ron Bolton: "When they said we were going to play, I said, "Oh my God!"
n Wideout Ricky Feacher: "Your spit turned to ice before it hit the ground."
n Running back Mike Pruitt: "The coldest day of my life."
n Sipe: "I thought if the NFL was ever going to postpone a game, it would be this one."
Kickoff was on time. Time froze as the arctic epic played out. Before one play, Raiders linebacker Matt Millen broke off half his mustache simply by wiping his face.
I shivered next to Danny Coughlin in that deep freeze of a baseball press box. It was no great football perch any day, far behind the west end zone. On this day, the view was comical.
We were glad to be behind a window, as it kept out the brutal wind, but afraid to breathe. The human vapor froze over the glass the moment it escaped.
Danny and I took turns scraping ice with notebooks and fingernails. It was hard to keep up. After halftime, he disappeared. I've seen him out and about over the years, so I assume he lived.
Tight end Ozzie Newsome used TV timeouts to bolt to sideline heaters. After a while, Nanook of the North clothes and electro-socks weren't enough. I couldn't stand the cold.
The TV network had a small heated room downstairs, a long way from the press box entrance. Getting there without missing much action required sprinting, full bore, down the stadium ramps, stealing a minute of network heat, and sprinting back up to the frozen window.
The stadium was full. The atmosphere something Jimmy Haslam and Joe Banner perhaps see in their dreams.
Ron Bolton's pick-six (not a term then), a missed extra point and two Cockroft field goals led to a 12-7 Browns lead going into the fourth quarter. The sound of 77,655 people (as the crowd was announced, meaning hundreds stayed home) was as warm as the air was cold.
Mark van Eeghen's second touchdown run put Oakland on top, 14-12. Yet, that whole season had been about last-minute rallies. There was a sense that not even a Titanic ice mass could stop one here.
The Browns drove.
Back then, writers emptied onto the sidelines with five minutes left. That is where we watched — from a vantage point closer than the players not in the game, frozen out of our gourds — Sipe throw the interception that lives in infamy, with 41 seconds left.
We trudged from the field to the Browns' locker room. There, writers and wide receivers had this in common: We were numb; we shivered uncontrollably.
There was no Internet to feed back then. On an afternoon-newspaper deadline, Stew drove us back to the warmth of the office in Canton.
Eager to capture history, I tapped out a paragraph about "the best laid schemes of mice and men" having gone astray.
I attributed the passage to Shakespeare. Learned readers later pointed out the mistake. "Of mice and men," they noted, traces to Robert Burns.
A wiser lad might have quoted Robert Freezes.


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The Dow dropped by triple digits and the S&P 500 slid to its lowest level since late July on Wednesday.
In fact, the Dow has erased 1000 points in only the last month and the Nasdaq 100 officially hit correction territory down 10% from its recent peak.
Many investors believe its uncertainty surrounding the fiscal cliff that's dragging down the markets. Without a compromise, a series of mandated tax hikes and spending cuts will start to take effect early next year that could push the U.S. economy into a recession.
And in his first press conference since re-election, President Obama held to his position that he planned in increase tax rates for families who make over $250,000.
"That makes good headlines," said Fast Money trader Guy Adami. "I'm sure you'll hear that on the 6pm news."
But Adami added that pros don't see the market that way. Pros believe "there's a lot more to it," said the managing director of stockMONSTER.com.
"There's been a slowdown in earnings. Also, the problems in Europe are deteriorating. It seems that Germany and France are getting dragged into the morass."
Also, "China is slowing and there are geo-political risks," he said, such as the Gaza attack.
That's why the market is selling off so sharply.
Trader Tim Seymour agreed.
And to make matters worse techincals are terrible, said Seymour who is founder of EmergingMoney.com. Lately the market has been trading very technically.
Trader Brian Kelly, founder of Shelter Harbor Capital, added that the bond market confirms the fear. "People are pulling money out of the capital markets but they're not putting it into bonds, the bond market is flat." That kind of price action suggests people are simply scared.
Of course, Warren Buffett often says be greedy when others are fearful. And trader Karen Finerman, president of Metropolitan Capital, thinks investors should heed his advice.
"I'm looking for things to buy," she revealed.Realogy is on my list and so is JPMorgan."
OptionMonster Jon Najarian said that the fiscal cliff certainly isn't helping matters. "The cliff is compounding the problem," Najarian said. "They've got to do something."
Posted by CNBC's Lee Brodie
Got something to to say? Send us an e-mail at email@example.com and your comment might be posted on the Rapid Recap. If you'd prefer to make a comment but not have it published on our Web site send those e-mails to email@example.com.
Trader disclosure: On November 14, 2012, the following stocks and commodities mentioned or intended to be mentioned on CNBC's "Fast Money" were owned by the "Fast Money" traders; Scott Nations is long BAC; Scott Nations is long BAC CALLS; Scott Nations is long C; Scott Nations is long YHOO; Scott Nations is long SPY; Scott Nations is long S&P VOLATILITY; Tim Seymour is long AAPL; Tim Seymour is long BAC; Tim Seymour is long INTC; Guy Adami is long C; Guy Adami is long GS; Guy Adami is long INTC; Guy Adami is long AGU; Guy Adami is long MSFT; Guy Adami is long NUE; Guy Adami is long BTU; Brian Kelly is long EWT; Brian Kelly is long SMH; Brian Kelly is long OIL; Brian Kelly is long EPV; Brian Kelly is long BRENTOILFUTURES; Brian Kelly is short EUROSTOXX FUTURES; Brian Kelly is short YEN; Karen Finerman is long AAPL; Karen Finerman is long BAC; Karen Finerman is long JPM; Karen Finerman is long WMT; Karen Finerman is long TGT; Karen Finerman is long MSFT; Karen Finerman is long GOOG; Karen Finerman is long EBAY; Karen Finerman is long M; Karen Finerman is short JCP; Karen Finerman is short SPY; Karen Finerman is short IWM; Karen Finerman is short SPY
CNBC.com and wires


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by Aleister G
College Insurrection
Greg Lukianoff recently sat down for an interview to talk about the new campus speech codes and their implications. Jim Epstein of Reason has the story and video.
The Ongoing Battle for Free Speech on Campus: Greg Lukianoff at the Museum of Sex
"The U.S. Department of Education just redefined harassment to make every single man, woman, and child arguably guilty of harassment in one fell swoop," says Greg Lukianoff, who is the president of the Foundation for Individual Rights in Education (FIRE), which advocates for free speech rights on campus.
Lukianoff is referring to a recent letter sent by the U.S. Department of Education and U.S. Department of Justice to the University of Montana that redefined harassment as "any unwelcome sexual speech." The letter also stated that it's intended as a "blueprint for colleges and universities throughout the country."
Heads up – there is at least one four letter word early on in the video.
View this article at College Insurrection.


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You didn't think we'd actually forget to celebrate one of the biggest beauty icons of all, did you?? Not only should we remember this pretty lady today on her birthday, but we should celebrate her sweet words of wisdom. No one knows beauty inside and out better than Audrey Hepburn, and thank goodness Mr. Sam Levenson was wonderful enough to jot down her advice…
"For attractive lips, speak words of kindness.
For lovely eyes, seek out the good in people.
For a slim figure, share your food with the hungry.
For beautiful hair, let a child run his or her fingers through it once a day.
For poise, walk with the knowledge that you never walk alone.
People, even more than things, have to be restored, renewed, revived, reclaimed and redeemed; never throw out anyone.
Remember, if you ever need a helping hand, you'll find one at the end of each of your arms. As you grow older, you will discover that you have two hands, one for helping yourself, the other for helping others.
The beauty of a woman is not in the clothes she wears, the figure she carries, or the way she combs her hair. The beauty of a woman must be seen from in her eyes, because that is the doorway to her heart, the place where love resides.
The beauty of a woman is not in a facial mode, but the true beauty in a woman is reflected in her soul. It is the caring that she lovingly gives and the passion that she shows.
The beauty of a woman grows with the passing years."
Happy Birthday, Audrey.
XO Lauren, Kristin and Amy Nadine


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The 2015 Masonry Codes and Specifications Compilation is a ready-reference that contains masonry requirements from the International Building Code® and Building Code® and Building Code Requirements and Specification for Masonry Structures (TMS 402-13/ACI 530-13/ASCE 5-13 and TMS 602-13/ACI 530.1-13/ASCE 6-13) in a single publication.
This compilation serves as a single-source reference for designers, contractors and inspectors.
This book includes:


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Style # 204248
AVAILABILITY: Unavailable for immediate shipment.
Borrowing from the boys never looked so glam! With a touch of rhinestones here and a dose of rose gold metal there, this bebe watch is sure to make your everyday a whole lot chicer. Try it with stacked bracelets for a cool weekend look.
- Metal.
- 6.5" (16.5 cm) around wrist.
- One size.
- Imported.
- Available exclusively online.
Round Rhinestone Tank Watch - ONLINE EXCLUSIVE is rated out of 5 by 12.
Rated 1 out of 5 by bonita from not what i was expecting, i think is horrible not what i was expecting, i think is horrible I would not recomend this item.
Date published: 2013-07-09
Rated 1 out of 5 by Yvonne2728 from This product looks cheap I received my watch today and was sadly disappointed. It is of cheap quality and looks too yellow and bright. Looks ghetto maybe if I would have got it in silver it would look better.
Date published: 2013-07-09
Rated 2 out of 5 by bebelovevic from Not good for small wrists the case diameter is way too big!! it was the size of my 26 year' boyfriend! plus the fact that the metal looks cheap ...
Date published: 2013-06-24
Rated 5 out of 5 by Anonymous from bebe watch! This is my second watch from bebe, and I absoulutely love it! I get so many compliments on both of them! One silver and the other gold! Love them!
Date published: 2013-06-20
Rated 5 out of 5 by Anonymous from love it...so cool yet girly chic i loved the watch...its a little big however it grew on me very quickly. im happy i chose gold because gold accessories are coming back and mixing colors and tones is very in which makes it helpful not being so old school matchy matchy... :)
Date published: 2013-06-04
Rated 4 out of 5 by Bebedenim from Huge This watch was way bigger than I expected & it kinda looked cheap
Date published: 2013-05-19
Rated 1 out of 5 by beya from It looks very cheap It is super big. It looks very cheap. Bad quality. I will be returning it.
Date published: 2013-04-17
Rated 3 out of 5 by LMathew26 from This product has great features but way too large! Didnot enjoy the moment when I received my package and noticed how huge the face of this watch was... It looks weird! Was disappointed!
Date published: 2013-04-13


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Eric Church, Carrie Underwood + More Join 2012 CMA Awards Performers Lineup
Eric Church, Carrie Underwood, Kenny Chesney and the Band Perry are the latest performers to be announced for the 46th annual CMA Music Awards, which will air live on from Nashville's Bridgestone Arena on Thursday, November 1.
Billboard revealed the latest additions to the scheduled lineup, which will include already-announced performances by Jason Aldean, Dierks Bentley, Luke Bryan, Kelly Clarkson, Little Big Town, Miranda Lambert, Brad Paisley and Zac Brown Band.
Underwood will have a packed schedule that evening. In addition to performing, she will also co-host the awards show with Brad Paisley for the fifth-consecutive year. The 'Good Girl' singer even earned a nomination in the Female Vocalist of the Year category.
In addition to performing, Chesney is nominated in the Entertainer of the Year category, as well as in the Music Video of the Year category for 'Come Over' and in the Musical Event of the Year category for his duet with Tim McGraw on 'Feel Like a Rock Star.'
Meanwhile, Church is poised to take home a slew of trophies this year with five nods in his direction. He is nominated for Male Vocalist of the Year and Album of the Year ('Chief'), plus Single of the Year, Song of the Year and Music Video of the Year, all for his chart-topping song 'Springsteen.'
The Band Perry are looking at a nomination for Vocal Group of the Year. The 2012 CMA Awards will air Nov. 1 on ABC at 8PM ET.


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Renowned documentarians to discuss their work
Morris, Lanzmann share interest in cinema as an investigation
Oscar-winning director Errol Morris will interview acclaimed filmmaker Claude Lanzmann Friday in the Wasserman Cinematheque on his recently-published memoir, "The Patagonian Hare," as well as other works.
The pair will sit down in the Edie and Lew Wasserman Cinematheque tomorrow from 11:30 a.m. to 12:55 p.m. The event is free and open to students but seating is limited. Contact Dona DeLorenzo to reserve a seat. The event will also be live-streamed.
"Both of these documentary giants share an interest in cinema as historical reinterpretation and as an investigation," says Alice Kelikian, chair of the Program in Film, Television and Interactive Media, which is sponsoring the event.
Lanzmann, 87, is best known for his epic documentary on the Holocaust, "Shoah," a nine and a half hour oral history. He also directed "Israel, Why," "Sobibor" and, most recently, "The Karski Report."
A French intellectual who made a career of documenting others' lives, Lanzmann has opened up about his own past in the new memoir, which has received excellent reviews. By turns resistance fighter, journalist, friend to Jean-Paul Sartre and lover to Simone de Beauvoir, Lanzmann details a wide array of life events.
Categories: Arts, Humanities and Social Sciences


text: Whenever I try to upload a picture to the site well under the "Maximum size of: 1048576 bytes" even 68,245 bytes, my computer connection goes completely dead. The little icon in my toolbar informs me that my connection has been unplugged. Weird huh? What could that be, I am uploading a valid extension (gif)?


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|Washington, D.C.
|High School:
|St. Albans School
2011: Made three solos in multiple games for a career-high... Had 14 solos and 20 overall stops as a defensive end with regular duty and some starts... Earned Yale's Woody Knapp Memorial Trophy for "cheerful disposition, leadership and unselfish devotion."
2010: Played nine games at DE... Made 2 solos and three overall stops... Broke up one pass.
2009: Saw action in eight games on special teams and as reserve linebacker. Solo tackle against Cornell and assist against Dartmouth.
2008: Played on JV team and recovered two opponent fumbles.
At St. Albans School: Earned six varsity letters between two sports... Captained football team to first conference championship in 13 years... Washington Post All-Metro second team... First-team all-conference junior and senior years... First-team All-DC Sports Fan & Player of the Year finalist... Fox News Player of the Year finalist... All-Examiner Player of the Week after championship game win in 2007... Made over 300 career tackles... Ran sprints for track team... Cum Laude Society... VP of senior class...
Personal: Clifford James Foreman is the son of Bruce Foreman and Joanne Young... Intends to major in history and political science... Interested in business career... Enjoys playing the saxophone... Worked with inner-city youth for three summers... Trumbull College resident.


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Encyclopedia of Islamic Doctrine
The Quran's Miraculous Relevance
Islam comprises all of civilization. Within Islam's sources are to be found all that is of value – the ultimate treasure trove of intellectual knowledge, practical guidance and spiritual wisdom. Islam is the fount for all of civilization's achievements and the diadem of its crown.
Islam carries, like a treasure-laden ship, within its deep hold are every sort of store and provision. Its sails are the sciences of jurisprudence and spirituality, like two wings of a bird, both of which it needs to carry its precious cargo of humankind across the vast expanse of the ocean of this life. At the helm of this vessel is the Leader and Master of mankind, Sayyidina Muhammad ÿ, under whose watchful eye and incalculable care it cuts through the depths of Allah's unsounded and uncharted Kingdom.
Encyclopedia of Muhammad's Women Companions and the Traditions They Related
This work is divided into two books: Book I contains all of the Traditions (ahadith) related by 150 women Companions of Prophet Muhammad (sall-allahu `alayhi wa sallam) according to the six canonical books of Sahih al-Bukhari, Sahih Muslim, Sunan Abu Dawud, Sunan Ibn Majah, Sunan al-Nisai and Sunan al-Tirmidhi. The Traditions are organized according to the Divine Law (Shari`ah), but this work begins with moral character development. A brief glance shows that women Companions related Traditions in many areas and not just in areas relating specifically to women. Where there is more than one Tradition on the same topic, one is presented and references to the other versions are indicated below that specific Tradition. Book II contains the biographies of over 600 women Companions of the Prophet including her name, her mother's name, the name of her children, the name of her husband (s) and where information is available from the earliest sources of Ibn Ishaq and Ibn Sad, and her biography. Paperback. Kreditai ir paskolos dirbantiems uzsienyje 2018 https://www.superpaskolos.lt/paskolos-dirbantiems-uzsienyje/
The Importance of Technology in the Development of Islamic Countries
What was the means by which the Prophet developed the Sahaba, their community and the entire Ummah? He taught them:
اطلب العلم و لو في الصين
Seek knowledge even if it be in China.[1]
It was through a cultural ethos informed by the Qur'ānic order to seek God's Signs in His creation and to ponder on them, that the sciences were built in Islam on the foundations of rational inquiry and logical thought while simultaneously seeking the philosophical and theological underpinnings to their observations. In this way, the Muslim world quickly surpassed its counterparts in developing science and research methodology, practical experimentation, and methods of confirming theory with observation - methods that are still followed today in modern laboratories and technical institutions.
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News Releases
DTE Energy, Enbridge and Spectra Energy to Develop New Major Pipeline to Connect
HOUSTON – DTE Energy (NYSE: DTE), Enbridge Inc. (NYSE: ENB) and Spectra Energy Corp (NYSE: SE) (the "Partners") today announced the execution of a Memorandum of Understanding (MOU) to jointly develop the NEXUS Gas Transmission (NGT) system, a project that will move growing supplies of Ohio Utica shale gas to markets in the U.S. Midwest, including Ohio and Michigan, and Ontario, Canada.
The proposed NGT project will originate in northeastern Ohio, include approximately 250 miles of large diameter pipe, and be capable of transporting one billion cubic feet per day of natural gas. The line will follow existing utility corridors to an interconnect in Michigan and utilize the existing Vector Pipeline system to reach the Ontario market. Upon completion of the project, Spectra Energy will become a 20-percent owner in Vector Pipeline, a joint venture between DTE Energy and Enbridge.
The new pipeline will serve local distribution companies, power generators and industrial users in the Ohio, Michigan and Ontario markets. It will include interconnects with Michigan Consolidated Gas Company, Consumers Energy and, through the Vector Pipeline, the Enbridge Tecumseh Gas Storage facility and Union Gas' Dawn Hub, both in Ontario.
The Partners have received expressions of interest for a significant level of firm capacity to anchor the project. An open season for the project is planned for fourth quarter 2012, with a targeted in-service as early as November 2015, depending on final market demand and commitments.
About DTE Energy
DTE Energy (NYSE:DTE) is a Detroit-based diversified energy company involved in the development and management of energy-related businesses and services nationwide. Its operating units include Detroit Edison, an electric utility serving 2.1 million customers in Southeastern Michigan, MichCon, a natural gas utility serving 1.2 million customers in Michigan and other non-utility, energy businesses focused on gas storage and pipelines, unconventional gas production, power and industrial projects, and energy trading. Information about DTE Energy is available at www.dteenergy.com.
About Enbridge Inc.
Enbridge Inc. (NYSE: ENB) is a North American leader in delivering energy and one of the Global 100 Most Sustainable Corporations. As a transporter of energy, Enbridge operates, in Canada and the U.S., the world's longest crude oil and liquids transportation system. The Company also has a significant and growing investment in natural gas gathering, transmission and midstream businesses, and an increasing involvement in power transmission. As a distributor of energy, Enbridge owns and operates Canada's largest natural gas distribution company, and provides distribution services in Ontario, Quebec, New Brunswick and New York State. As a generator of energy, Enbridge has interests in close to 860 megawatts of renewable and alternative energy generating capacity and is expanding its interests in wind and solar energy, geothermal and hybrid fuel cells. Enbridge is ranked as one of Canada's Greenest Employers and one of the Top 100 Companies to Work for in Canada. For more information, visit www.enbridge.com.
About Spectra Energy
Spectra Energy Corp (NYSE: SE), a FORTUNE 500 company, is one of North America's premier natural gas infrastructure companies serving three key links in the natural gas value chain: gathering and processing, transmission and storage, and distribution. For more than a century, Spectra Energy and its predecessor companies have developed critically important pipelines and related infrastructure connecting natural gas supply sources to premium markets. Based in Houston, Texas, the company's operations in the United States and Canada include more than 19,000 miles of transmission pipeline, approximately 305 billion cubic feet of storage, as well as natural gas gathering and processing, natural gas liquids and local distribution operations. The company also has a 50 percent ownership in DCP Midstream, one of the largest natural gas gatherers and processors in the United States. Spectra Energy is a member of the Dow Jones Sustainability World and North America Indexes and the U.S. S&P 500 Carbon Disclosure Project's Carbon Disclosure Leadership Index. For more information, visit www.spectraenergy.com.
About Vector Pipeline, L.P.
Vector Pipeline L.P. is a partnership between Calgary-based Enbridge Inc. (NYSE/TSE: ENB), with a 60-percent interest, and Detroit-based DTE Energy Company (NYSE: DTE), with a 40- percent interest. Information about Vector Pipeline is available at www.vector-pipeline.com.
Contact Information:
DTE Energy
Media: Len Singer
Analysts: Mark Rolling
Enbridge Inc.
Media: Jennifer Varey / Larry Springer
403-508-6563 / 713-821-2253 or toll-free 888-992-0997
Analysts: Jody Balko
Spectra Energy
Media: Wendy Olson
713-627-4072 or 713-627-4747 (24-hour media line)
Analysts: John Arensdorf


text: Is there any kind of public health office near you? They might have a free breastfeeding clinic that might be able to give you some support, or maybe direct you to an LC that might be willing to do a payment plan? But I really think that if you give it time, especially avoiding pumping and bottles, that your supply will regulate and your LO will figure out how to deal with the milk without clamping down. When I had so much pain at the beginning, my husband too suggested that I 'just pump' and give her a bottle instead, but the pump is really no fun and so much more work!


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Invensis Learning's Ethical Hacking Foundation Training Course in Gold Coast is delivered by highly qualified trainers with extensive experience. The EXIN Ethical Hacking Foundation certification provides IT professionals with a complete understanding and technical knowledge of the principles behind Ethical Hacking. The different methods used to test and determine the security of the IT infrastructure within an organization are covered in the Ethical Hacking Foundation Course.
This Ethical Hacking Foundation Certification training course accredited by EXIN is ideal for security officers, network administrators, network architects, security auditors and any other professional who wishes to improve IT security and more. Participants attending this training will receive a hard copy of the course material.
We deliver Ethical Hacking Foundation Training in Gold Coast through classroom and live online virtual modes. Enroll now and gain this Ethical Hacking Foundation certification in Gold Coast today.
|Training Modes
- Instructor-led Classroom Training ( Request for Training )
- Instructor-led Online Training ( Request for Training )
- On-site Group Training ( Request for More Information )
- Focused 1-to-1 Training
|Areas of Study
- Evaluating the security and vulnerabilities of computer systems and networks
- The legal implications, types and phases of ethical hacking
- The different types of tools used and the functions involved
- Finding information in a computer, online or in a network of computers
|Ethical Hacking Foundation Training
|Request for the Ethical Hacking Foundation training in Gold Coast
|Ethical Hacking Foundation Course Duration
|Ethical Hacking Foundation Training Course Syllabus
|Ethical Hacking Foundation Certification Eligibility Criteria
There are no pre-requisite criteria to take up Ethical Hacking Foundation examination. However, an Ethical Hacking Foundation training and knowledge of Linux is highly recommended.
|Ethical Hacking Foundation Exam Format
|Who Should Attend Ethical Hacking Foundation Certification Training
Job roles that can benefit from Ethical Hacking Foundation training course in Gold Coast include, but are not limited to:
Training delivery modes for effective learning
Live Online
1 to 1
The candidate will learn about the legal implications of hacking, the different types of hackers, the difference between the white and black box test and the different phases in the hacking process.
The candidate will learn about the different kind of tools for Network Sniffing, the function of HTTP and how to extract information from HTTP headers.
The candidate will learn to find information of his own network adapter, explain Airodump-NG and know the different kind of functions of tools within Aircrack.
The candidate knows how to find information on a target online, to scan a target, how to combine tools, find vulnerabilities based on scanning results and how to perform manual fingerprinting.
The candidate knows the steps to test for SQLi vulnerabilities, how to extract data with SQLi, how to create an XSS PoC (Proof of Concept), the basics of session hijacking, to bypass basic XSS filters, how RFI is performed and the basic functionalities of php shells such as r57 and c99.
The daily agenda of the 2-day Ethical Hacking Foundation training is detailed below:
The candidate will learn...
The candidate will learn...
The candidate will learn...
The candidate will learn...
The candidate will learn...
The Candidate will learn...
The Candidate will learn...
The Candidate will learn...
The Candidate will learn...
The Candidate will learn...
The Candidate will learn...
The Candidate will learn...
As part of your Ethical Hacking Foundation training, you will receive:
At Invensis, we provide Ethical Hacking Foundation training in Gold Coast in three different learning modes in instructor-led classroom training, instructor-led online training, and on-site group training.
Yes, the examination fee is included in the course fee.
The Ethical Hacking Foundation credential does not have an expiry period, and the certification is valid for life.
Yes, Invensis Learning is an EXIN Accredited Training Organization (A.T.O) for providing Ethical Hacking Foundation Training and Certification course worldwide.
Individuals and Enterprises can make payment for the training through 2 different modes such as –
For more information on payment details, please contact us at firstname.lastname@example.com
Please call us, join our Live Chat for instant support, or Request a Call Back to have your query resolved.
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Ten Tips to Keep Your Pet Safe this Summer and All Year Long
As summer approaches, we again enjoy our outdoor community and plan driving and camping trips. For pet owners, these activities also mean extra special consideration for dogs, cats and other animals.
As summer approaches, we again enjoy our outdoor community and plan driving and camping trips. For pet owners, these activities also mean extra special consideration for dogs, cats and other animals.
With this in mind, the International Fund for Animal Welfare has compiled some tips on how you can be prepare to include your animals in the coming months whether in your immediate community or abroad. When spending time in the summer heat, make sure your pet stays happy and healthy by following these pet safety tips:
- Keep Things Cool: Some of us may believe that hotter is better, but our animal companions don't necessarily agree. Make sure that animals spending time outdoors always have access to a shaded area and plenty of fresh, clean water.
- Don't Get Bugged: Bugs are just as annoying to your pets as they are to you. Don't leave your pet in a buggy area, and consult with your vet about prevention for fleas and ticks.
- Chill Out: Be careful not to over-exercise your pets or let them stand on asphalt for an extended period of time. Hot asphalt can mean damaged, painful paws and, over-exertion can lead to a rapid increase in body temperature.
- Practice Car Safety: Never leave an animal in a parked car, even for a short period of time. Your vehicle can get extremely hot in a matter of minutes, quickly causing your pet distress or even death. If it feels hot to you, it feels even hotter for your pet. And if you see an animal left in a car, immediately notify management of the appropriate store, or contact animal control. If you become concerned that your pet has overheated, place them in a cool, well-ventilated area, provide plenty of fresh, cool water, and immediately contact your vet.
When jet-setting off on new adventures, it's common to encounter animals interacting differently in their communities than we do at home. If your travels leave you concerned about the welfare of local animals, these are things you can do to help:
- Don't pass judgment too quickly: It is important to remember that some communities live with dogs, cats, and other animals in ways that are different from what you're accustomed to. Try to be supportive of the community by first talking with animal owners. Encourage individuals to provide adequate food and shelter for their furry companions. Trying to understand the way a community interacts with its companion animals on a daily basis is a vital and unique aspect of being an animal-loving tourist abroad.
- Don't turn a blind eye: You should always report any instance of animal abuse and cruelty to the appropriate authorities Remember, animal mistreatment is bad for tourism and reflects poorly on the community, so it is important to make your concerns known, respectfully. Tell your tour operator, hotel management, or local shop owners that you're concerned about the animals you see. Let them know that good animal welfare is good for business.
- Know where your money is going: Often, animal exploitation and the tourism industry go hand-in-hand. Animals used for entertainment purposes, rides and travel, or photo opportunities often deal with cruel treatment and unimaginable living conditions. Always research tourist programs ahead of time to avoid supporting services that are not animal-friendly. Also, be sure to avoid purchasing souvenirs made from animal and wildlife products.
- Practice safety first: Roaming dogs and cats may or may not be vaccinated against diseases like rabies, or enjoy contact with new people. Use caution when interacting with any animal you don't know. Don't attempt to chase or pick-up an animal that runs away, is on private property, or looks threatening. If you believe the scenario may jeopardize the health and safety of you or the animal, it is best to keep your distance and wait for a trained professional, such as an animal control officer, to handle the situation.
- Be proactive, plan ahead: It is always better to be prepared. You can investigate and contact local animal shelters, humane societies, and veterinarians in the event that you ever encounter an animal in distress. A quality organization is one that provides basic care including vaccination and first aid to animals, and does not hoard or overcrowd animals in its holding space.
- Model Compassion: Inspire locals to improve their animals' care by setting a good example for how animals should be treated. Interact with animals in a kind, gentle, and responsible manner. By modeling compassionate behavior, you show that animals have value and are worthy of care and consideration.
Phew, that's 10! ;)
For more information about the International Fund for Animal Welfare effort to save animals around the world visit https://www.ifaw.org


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Maker's Mark Distillery Kitchen
At the beginning of the Maker's Mark distillery tour in Loretto, Kentucky, we spent a little time in the Heritage Center, built in the 1840s and home to a several-generations-back area distiller. Now, family photos (of the Maker's Mark Samuels family) adorn the home's walls, architectural drawings show the home's origins, and the bourbon flavored coffee lures you into a 1950s-inspired kitchen. Updated but true to the Maker's Mark early years...
...the kitchen was re-created here as the place where red wax dipping was tested and perfected by the Samuels family. While the whole Heritage Center home was rich in detail and history, the kitchen -- with its red and blue charm, vintage details, and family cookbooks on display -- stood out as a room alive in tastes and history. Enjoy this online photo tour, and definitely check out the entire distillery tour in person if you find yourself in Kentucky (it's free)!
More information for touring the Maker's Mark Distillery can be found here.
Images: Philippa Djemal


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Tag Archives: Pre-paid instrument
Open Application Programming Interfaces (API): Purpose and Possibilities
Application Programming Interface or API, a software programme, acts as a bridge between disparate applications. It performs the intended function when a set of instructions are provided through a user interface (UI). The front-end of UI is usually a website or mobile application. The following diagram illustrates the basic architecture of any API-based business model:… Continue reading


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This article provides information on signing a DNS zone in Windows Server 2012 or 2012 R2.
Before signing a DNS zone, you may wish to review the following articles:
Also be aware that some zones may not benefit greatly from being signed. A public DNS zone - a zone accessible from the internet - is far more likely to be the target of a DNS spoofing attack than an internal zone that is only accessible to machines on a local network. Unless a corporate security policy or other requirement mandates it, signing an internal zone may not provide enough of a benefit to outweigh the additional overhead associated with it.
The procedure for signing a DNS zone has been greatly improved in Windows Server 2012 over that in Windows Server 2008 R2, but it is still fairly complex. Follow these steps to sign a zone:
Note: Although the following steps illustrate the signing of a forward lookup zone, the same procedure can be used to sign reverse lookup zones.
Article ID: SLN290640
Last Date Modified: 10/07/2014 11:10 AM
Thank you for your feedback.


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Come Party With Me: Housewarming Party — Invite
Hunting for a new house, packing everything you own, and moving is seriously exhausting. However, once you are settled into your new space, consider hosting a housewarming party. Think of the housewarming like a reward for the move.
Invite friends and family members over for a tour and tapas. Introduce them to your place while tantalizing their tastebuds with delicious bites. Start by selecting a date and sending invitations. To learn how I made these simple, stylish invites,
To make a similar invite you will need the following supplies:
- colored paper
- colored cardstock
- scissors
- glue
- satin ribbon
- single hole punch
- a key
- pencil
- computer and printer
To assemble the invite:
- Create a new document in Microsoft Word. Insert a text box on the left hand side of the page. Fill the box with the details of your party. I used the font Bell MT in size 12 to write this message:
Although our address is new,
the door is always open for friends like you!
Please join us in celebrating our new home.
Stop by for a tour and tapas on
Saturday July 19, 2008
6:00 pm – 10 pm
Sean & Elena
45 Main Street
San Francisco, CA 94104
Please add our new address to your records.
On the other side of the page insert another small square shaped text box. Write home sweet home inside the box (I used Lucida Handwriting). Directly above the square, insert a triangle to form the outline of a house.
- Print out on plain white paper. Check for grammar and spelling mistakes. Once satisfied with the text, print out on the colored paper.
- Cut the invite down to size and mount on the cardstock. Set aside.
- Cut out the little house.
- With the pencil, trace the outline of the key onto a piece of paper. Cut out the shape, so you have a paper key.
- Punch a hole in the top of the key and the triangle of the house.
- Slide the ribbon through and tie a small knot.
- Glue to the top of the invite, slide into an envelope, and send.


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Scores of stunning sculptures are set to appear in the gardens of Chatsworth House.
More than 20 statues by different artists from around the world including Xu Bing, Marc Quinn, Christopher Le Brun and Aristide Maillol will be showcased at the stateley home as part of its Beyond Limits exhibition.
The event, which has been held at Chatsworth House since 2006, will launch on Monday and runs until Sunday, October 26.
The above slideshow, put together by Lewis Walker, features pictures by our photographer Jason Chadwick.


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Please excuse my newbie ignorance, would really appreciate someones help. I am trying to install Joomla for web design on my PC, and realised I would need a web server. I googled and found Apache as the defacto choice for most developers.
I have downloaded the version for Windows.
a) I reviewed a tutorial video, which shows that after downloading the version for windows, you will find an the Apache icon for installation. When I downloaded the files, all I can see is a folder with lots of sub-folders......so I am confused as to what I should run for installation.
b) Also....what other files should I run and install if I want to set-up a web page (SQL, Perl????)
Confused, please help.


text: A stylish and portable in-vehicle accessory, designed to rapidly charge your phone`s battery in approximately two to three hours. Simply plug it into your car`s vehicle power socket and connect it to your phone - enjoy unlimited talk and standby time, while your phone is charging! Fits most in-vehicle power port sockets. New design - illuminated Motorola logo indicates power is made from socket to phone. Approximate weight and dimensions: 4.3oz, 86mm x 35mm (round) Coil cord length when stretched: 2.4m Auto resetable fuse - no need to ever replace Compatibility: Motorola MPx200, MPx220, RAZR V3 phone.


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For price, size and availability of original paintings contact Leo for a full catalogue.
You can see Leo's newest originals and more at the Studio/Gallery.
Leo's Watercolours are available as prints in various sizes and as cards.
See contact for details.
If you like this painting and you'd like to see more similar ones let Leo know as he may have more for you to see.
Hungerford Bridge
< all watercolours
< previous | next >


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We have a very simple set of rules [1] to follow here on the forum. Recently, there have been people registering with the sole purpose of spamming the site with stupid links. Such users will be banned immediately, so don't even bother.
I hope that we won't have to start screening site registrations, because it is generally a pain in the behind to do so, but if this continues we may have to go that route.
Registered users, if you do see a spammer in action, please use the X link at the bottom of each topic posting or comment to report them. Doing so will make such messages disappear from public view, and then mods/admins can deal with them by throwing the offenders out.
The Big Onigiri.
- Wherever you go, there you are. -
[1] http://justbento.com/forum/forum-rules-and-guidelines


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Advanced Learning provides services to meet the instructional needs of students whose abilities, talents and potential for accomplishment are so advanced they require special provisions to meet their educational needs.
We provide services for students who are currently enrolled in Seattle Public Schools and who have been evaluated for and designated as needing advanced learning services. We also assist students who are transferring into the school district who need to be tested for eligibility.
Highly Capable Services, which serves students in grades K-12, provides one or more of the following: enhanced curricula, appropriately differentiated instruction, deeper learning opportunities and/ or accelerated pacing. Read more about Highly Capable Services.
Advanced Learning Programs (Spectrum), which serves students in grades 1-8, provides advanced curriculum in reading/ELA and math. Read more about Advanced Learning Programs and Services.
Gifted students are identified by an exceptional ability to learn and reason beyond their same-age classmates. Advanced learners include gifted students with disabilities (twice-exceptional students) and students with exceptional abilities or potential from all social-economic, ethnic and cultural populations. Read more about identifying students for advanced learning.
For more information about eligibility criteria: Read more about Advanced Learning Eligibility Criteria.
Anyone may recommend a child for the eligibility evaluation process, including teachers, other staff, parents, students and community members. Only the student's parent or guardian may make an official Referral. Read more about referring students.
Students who are referred for advanced learning to be considered for Highly Capable Services or Advanced Learning Programs participate in testing during the assessment cycle window to determine eligibility. Read more about testing and evaluation process.
Contact Advanced Learning
Have a question?
Additional department contacts
Related Links
Advanced Learning Task Force
Key Dates
See our calendar webpage for upcoming dates and general referral and testing windows.
Advanced Learning Updates


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The mellow tones of accordion, dynamically expressed in chords create very pleasant and transparent sound.
Similar Tracks
Thank you for your interest in my music, and for supporting it!
Dear customers! Please send links to your work where you use my music.
I can put them in my profile. Thank you! email@example.com


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Cakes and Road Trips IVAbout this photograph
In his DREAM WORLD series CAKES AND ROAD TRIPS, Anatol shows his inner conflict between the desperate urge for freedom and his longing for a home and some stability on the other hand. Anatol uses symbols like balloons standing for freedom and easiness, a caravan, the very symbol for his nomadic, restless life...he then breaks those symbols by tying the balloons so they cannot really break free and staging the caravan showing it obviously has not been moved for a while. Welcome to Anatol?s Worlds.Read more Read less
The photographs are carefully packaged in order to ensure their optimal protection during transport.
For arty holidays
Numbered Limited Editions With Certificate of Authenticity
From S$199.00
From S$189.00
From S$189.00
Of Romanian-French origin, Anatol grew up in a lot of different places and environments - due to his parent's worldwide engagements, the family was constantly on the move.From his early childhood on, travelling into his colorful dream worlds has always been a way to escape from the high expectations and requirements his family imposed on him. His dream worlds became a very important reality - something he could take with him wherever he was forced to move. Or to put it in his words: I became aware of the magnitude and significance of distancing myself from the world as far as possible around the age of 8.With his art, Anatol found an instrument to open the curtains and show his dream worlds to a greater audience. THE DREAM SERIES is his first series in photography. Welcome to Anatol's Worlds.


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After seven mostly successful seasons, Warwick football coach James Sciarra will not be back for the 2013 season.
After seven mostly successful seasons, Warwick football coach James Sciarra will not be back for the 2013 season.
According to team sources, Warwick schools Superintendent Ray Bryant informed Sciarra last Friday that he wouldn't be recommended by the school board to return this fall. Varsity coaching appointments are made on a year-to-year basis.
"I'm not the head football coach any longer," Sciarra said on Monday. He declined further comment.
Asked about Sciarra not returning as coach, Bryant said: "He's made a decision not to coach anymore."
Sciarra was an offensive lineman and linebacker at Warwick, graduating in 1997. As a coach, he went 40-25, helping the Wildcats to the Section 9 Class AA championship game in 2009 and 2011. Warwick finished 6-3 this past season, losing to Monroe-Woodbury 14-13 in the Section 9 Class AA semifinals.
Sciarra had only one losing season — 2008 — but according to team sources the coach was "disconnected" from several of his players.
"This is obviously the administration's choice and they are going to do what's best for the players," said junior linebacker A.J. Sakac. "Coach Sciarra was a hell of a coach, he was smart, but he was missing one part. He was nothing more than a coach. There was no relationship out of football. He didn't really talk to his players on a daily basis. I respect him for being the coach and wish him luck with his future in coaching."
Sciarra, a math teacher at Warwick High, informed the team of his departure at a short meeting on Monday morning at the school. He referred any questions his players had about the coaching change to athletic director Greg Sirico. Sirico, who coached the football team from 1996-05, couldn't be reached for comment on Monday.
"It's pretty sad to see coach Sciarra leave, but the administration knows what's best for the team," said junior defensive back Matt Cattani. "I'm not going to try to start anything. There is nothing we can say to argue. Some players were upset with coach Sciarra, but I personally didn't feel that way. Right now, I just want to see where the team goes from here."


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Cub Scout Map and Compass
From MeritBadgeDotOrg
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Belt Loop Requirements
Complete these three requirements:
- 1. Show how to orient a map. Find three landmarks on the map
- 2. Explain how a compass works.
- 3. Draw a map of your neighborhood. Label the streets and plot the route you take to get to a place that you often visit.
Academics Pin Requirements
Earn the Map and Compass belt loop, and complete five of the following requirements:
- 1. Define cartography.
- 2. Make a poster showing 10 map symbols and their meaning.
- 3. Read a book or story about a famous explorer or navigator. Tell your den or family what you learned.
- 4. Make a simple compass with a magnet and pin.
- 5. Explain the difference between latitude and longitude and show them on a map or globe.
- 6. Draw a compass rose for a map. Label north, south, east, and west.
- 7. Study a blank map of the United States of America. Label your state, and the states that share its boundary lines.
- 8. In the field, show how to take a compass bearing and how to follow it.
- 9. Show how to measure distances, using a scale on a map legend.
- 10. Measure your pace. Then layout a simple compass course for your den to try.
- 11. Using a road map, determine how many miles it is between two major cities or familiar destinations.
- 12. Explain what the different map colors can mean on a map.


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Cultural diversity
Produced under the programme "Tagore, Neruda and Cesaire, for a Reconciled Universal", this CD is part of the collection "Songs of Rabindranath Tagore". The collection is a selection of songs translated by professor Sugata Bose (Harvard University) published in celebration of the 150th Birth Anniversary of Rabindranath Tagore.
All songs performed by Shama Rahman, from Bangladesh
This CD contains eight songs of Tagore presented under "Puja", "Prakriti", "Swadesh", "Bichitra" and "Prem". (available here)
on this subject: Launch of five CDs entitled "Celebrating Tagore"
Type: Compilation
Extract: 4 min. Total length:
Credits: Shama Rahman, performer. Media Access, India, producer. UNESCO, co-producer.
Published in:
Rights/Droits: Media Access
LICENSING: for inquiries about licensing or requests for CD/DVD copies of this material, please contact the producer or the author directly. You may also wish to consult our FAQs 6 to 9


text:
LANSING—State Sens. Phil Pavlov, R-St. Clair Township, and Mike Green, R-Mayville, are inviting Bay and Thumb area residents in the 25th and 31st Senate districts to a public town hall on Monday, Sept. 22 in Sebewaing to discuss legislative and other efforts to protect Lake Huron from a proposed Canadian nuclear waste dump.
Sen. Phil Pavlov, R-St. Clair Township;
Sen. Mike Green, R-Mayville; and
Anyone interested in the topic.
A public town hall meeting to inform residents about a Canadian nuclear waste dump proposal and plans by Michigan lawmakers to stop it.
Canadian officials propose to bury 7 million cubic feet of radioactive waste less than a mile from the shore of Lake Huron, directly across the lake from residents of the Bay and Thumb regions.
Green and Pavlov are leading an effort in Lansing to halt construction of the dump. Their legislation has passed the Michigan Senate unanimously and awaits action in the House of Representatives. More than 60 communities throughout the region have recently passed resolutions in support of the measures.
Monday, Sept. 22
6:30 to 8 p.m.
Sebewaing Township Hall
14 East Sharpsteen St.
Sebewaing, MI 48759
For more information, contact Green's office at 1-517-373-1777.


text:
May 26, 2011
Table of Contents
Ah, there's nothing like the smell of a fresh antiretroviral in the morning. It's been more than three years since we've gotten a whiff of that lovely scent here on the HIV treatment ranch: The last HIV medication approved in the U.S. was the non-nucleoside reverse transcriptase inhibitor (NNRTI) Intelence (etravirine, TMC125), back in January 2008.
Now we have another NNRTI: The U.S. Food and Drug Administration (FDA) approved Edurant (rilpivirine, originally known as TMC278) on May 20, and it should hit U.S. pharmacies sometime next month, according to the drug's manufacturer, Tibotec.
Unlike Intelence, which was approved for use in people who had developed resistance to other HIV medications -- particularly those within the NNRTI class, such as Sustiva [efavirenz, Stocrin] and Viramune [nevirapine] -- Edurant was approved as a first-line treatment option. (This AIDSinfo fact sheet provides much more info on the basics of Edurant, including dosing and side effects.)
We wanted to delve more deeply into Edurant's approval, what makes the drug unique, what side effects and other concerns people should watch out for, and how the introduction of Edurant may change the answer to the question, "What should I start HIV treatment with?" So we spoke to one of the people most qualified to answer those questions: Cal Cohen, M.D., a prominent HIV clinician-researcher who was the lead investigator for the clinical trials that led to Edurant's approval.
Incidentally, as Dr. Cohen and a Tibotec representative both confirmed, the correct pronunciation of Edurant is EE-der-int, and the generic name, rilpivirine, is pronounced rill-PIHV-er-in.
[Disclosure: Dr. Cohen conducts research on behalf of and consults on the advisory board for Tibotec Therapeutics, as well as for Bristol-Myers Squibb Company, Gilead Sciences Inc., and Roche. However, Dr. Cohen notes he has not received compensation from Tibotec for his role as lead investigator of the ECHO and THRIVE studies that led to Edurant's FDA approval.]
What makes Edurant different from the other 30 HIV pills and combo drugs that have been approved by the FDA?
One reason this drug is distinct is that it went up head-to-head against efavirenz, which is amongst the drugs that have always performed the best in terms of establishing virologic suppression. Edurant, in combination with two nucleosides, allowed patients to get their viral load controlled at a rate that, looking at the entire population, was similar to patients on efavirenz -- and it did so with fewer side effects.
That, of course, is the combination we all want: a simple, once-daily combination that will get your viral load controlled with as few side effects as possible. That's the constant search; that's why we look for new drugs. And Edurant provided many of these attributes in these studies.
What are we talking about in terms of the efficacy numbers when they were comparing Edurant against Sustiva?
In the overall analysis, in terms of getting the viral load controlled, the percentage of volunteers who reached an undetectable viral load on Edurant was 83 percent, versus 80 percent for those taking Sustiva.
You mentioned that Edurant appears to be more tolerable than Sustiva. In what way? How do the side effects compare?
For me, one of the easiest ways to summarize the fact that there were fewer side effects is to look at how often people stopped participating in the study due to adverse events, due to side effects, at the end of one year. Because, I think, while people might have a side effect for a week or two and then it goes away, it's a bigger deal for somebody to say, "I've tried this, I've tried it a while more, and it's just not good enough. I can't do this. I have to leave your study." That's a bigger thing.
One of the more striking findings in the study is that only 2 percent of people on Edurant stopped study participation. But in contrast, 8 percent on efavirenz did so, if I have the numbers exact. To me, that's an important thing, because I think what we're all looking for is a combination that allows me to say to somebody, "If you take this, the odds that you're gonna tell me you don't want to stay on this medicine anymore due to side effects is amongst the lowest we have in our field." And that's a pretty reassuring start.
Is that one of the reasons why this was approved for first-line therapy, because of the low toxicity, as opposed to an attempt to develop it as a more treatment-experienced option?
The studies were only done in treatment-naive patients, or patients just starting therapy for their first time, so the label is limited to that because those are the only populations that were studied for this drug. I think there are many reasons for that, including: These days, most people -- though not everybody, most people -- who start on a combination can, with either the first or second combination, stay on that regimen for hopefully the rest of their lives, and certainly our studies are pretty reassuring [that this can be the case].
As a result, there really aren't a lot of people in search of rescue regimens. And as a result [of that], a lot of the emphasis in clinical trials these days is to find the best way to start, because if you do that, odds are good you'll be able to stay on that from now on.
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