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text: Orbital neuroblastoma metastasis A case report and literature reviewYang, Wan-Ju MD; Zhou, Yuan-Yuan MD; Zhao, Fang MS; Mei, Zhong-Ming MS; Li, Shuang MD∗; Xiang, Yi MD∗Section Editor(s): NA., Medicine: September 2019 - Volume 98 - Issue 36 - p e17038 doi: 10.1097/MD.0000000000017038 Research Article: Clinical Case Report Open Abstract Author InformationAuthors Article OutlineOutline Article MetricsMetrics Rationale: Neuroblastoma is one of the most common tumors found in children, and mostly arises in the adrenal gland and paravertebral regions. Orbital neuroblastoma metastasis is relatively rare, and is associated with poor prognosis. Since the symptoms and signs of orbital neuroblastoma are not specific, its diagnosis remains challenging. Patient concerns: A 3-year-old girl presented with periorbital ecchymoses (raccoon eyes) and proptosis for 40 days. Diagnoses: Abdominal magnetic resonance imaging (MRI) and sonography analysis revealed a large mass in the left adrenal gland (primary tumor). The computed tomography and MRI further revealed multiple soft tissue masses in the skull and both orbits with erosion of the adjacent bones (the metastasis). The histological analysis of the tumor removed from the right orbit confirmed the diagnosis of neuroblastoma. Interventions: The mass on the right face was surgically removed. Outcomes: The patient exhibited no deteriorative signs at the 6-month follow-up. Lessons: Clinical manifestations, such as periorbital ecchymoses and proptosis, in combination with radiological analysis and histological findings, are important for the diagnosis of orbital neuroblastoma metastasis. Department of Ophthalmology, The Central Hospital of Wuhan, Tongji Medical College of Huazhong University of Science and Technology, Wuhan, Hubei, China. ∗Correspondence: Shuang Li, Department of Ophthalmology, The Central Hospital of Wuhan, Tongji Medical College of Huazhong University of Science and Technology; No. 26 Shengli street, Wuhan 430014, Hubei, China (e-mail: firstname.lastname@example.com); Yi Xiang, Department of Ophthalmology, The Central Hospital of Wuhan, Tongji Medical College of Huazhong University of Science and Technology; No. 26 Shengli street, Wuhan 430014, Hubei, China (e-mail: email@example.com). Abbreviations: CT = computed tomography, FFA = fundus fluorescein angiography, H&E staining = Hematoxylin-eosin staining, MRI = magnetic resonance imaging, NSE = neuron-specific enolase, OCT = macular optical coherence tomography, SYN = synaptophysin, TH = tyrosine hydroxylase. How to cite this article: Yang WJ, Zhou YY, Zhao F, Mei ZM, Li S, Xiang Y. Orbital neuroblastoma metastasis. Medicine 2019;98:36(e17038). W-JY and Y-YZ authors have contributed equally to this work. A written informed consent was obtained from the patient's legal guardian for the publication of this case. This work was supported by the National Natural Science Foundation of China (No. 81300761) and the Research Projects of Wuhan Health and Family Planning Commission (WX18A08, and WX17Z02). The authors have no conflicts of interest to disclose. This is an open access article distributed under the Creative Commons Attribution License 4.0 (CCBY), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. http://creativecommons.org/licenses/by/4.0 Abstract 1 Introduction 2 Case presentation 3 Discussion and conclusion Author contributions References Back to Top | Article Outline 1 Introduction Neuroblastomas are the most frequently identified extracranial tumors that affect children under the age of 4 years old, with an incidence of approximately 1 to 3 in 100,000 cases.[1,2] These account for approximately 6% to 10% of all pediatric tumors and 15% of tumor-related deaths in children.[3] Neuroblastomas are neuroendocrine tumors that can originate anywhere in the sympathetic nervous system, although these are most commonly found in one of the adrenal glands. The clinical symptoms and signs of neuroblastomas are commonly atypical, depending on the location of the primary tumor and metastases. Although metastasis to the orbits has been well-documented for neuroblastomas presenting with various symptoms, such as periorbital ecchymoses (raccoon eyes) and proptosis,[4] neuroblastoma cases with initial symptoms of orbital involvement are rare, accounting for approximately 8% of all neuroblastomas.[5] In the present study, we report a specific case of a 3-year-old girl with neuroblastoma, who presented with initial signs of periorbital ecchymoses (raccoon eyes) and proptosis. In addition, the clinical, radiological, and histopathological studies of orbital neuroblastoma metastasis reported in the literature were summarized. Back to Top | Article Outline 2 Case presentation The present study was approved by the Ethics Committee of the Central Hospital of Wuhan, Tongji Medical College of Huazhong University of Science and Technology. All procedures performed in studies that involved human participants were in accordance with the ethical standards of the institutional and national research committee, and the 1964 Helsinki declaration and its later amendments, or comparable ethical standards. A written informed consent was obtained from the patient's legal guardian. A 3-year-old girl was admitted to our hospital presenting with periorbital ecchymoses and proptosis for 40 days. On examination, multiple hard masses were palpated on both the face and head. Bilateral subconjunctival hemorrhages, periorbital ecchymoses (raccoon eyes), and proptosis were identified (Fig. 1A). Fundus fluorescein angiography (FFA) and macular optical coherence tomography (OCT) revealed no abnormality on the fundus. The systemic evaluations, which included routine blood and urine tests, hepatic and renal function examinations, and the serum glucose test, revealed unremarkable findings, with the exception of anemia. The electrocardiogram and chest roentgenogram results were also unremarkable. However, an abdominal mass was palpated by a pediatrician. Figure 1 The computed tomography (CT) scan highlighted multiple soft tissue masses in the skull and both orbits, with evident erosion into the adjacent bones (Fig. 1B). The magnetic resonance imaging (MRI) also revealed multiple masses in the head-face area, and a large mass in the left suprarenal gland (Fig. 1C and D). The abdominal sonography examination revealed a heterogeneous hypoechoic mass in the left adrenal gland (Fig. 1E). The mass on the right face was surgically removed. The tumor was cardinal red, with an irregular surface (Fig. 1F). The hematoxylin-eosin (H&E) staining revealed small uniform round cells with a scanty cytoplasm and darkly stained nuclei. Furthermore, nodules and Homer-Wright pseudorosettes were occasionally found, with no ganglionic differentiation (Fig. 1G). The tumor was immunopositive for synaptophysin and neuron-specific enolase, but immunonegative for S-100 and leukocyte common antigens. According to the clinical, radiological, and histopathological findings, the patient was diagnosed with stage IV neuroblastoma. The patient was transferred to the Department of Pediatric Oncology for the treatment of the tumor. However, the patient refused the recommended chemotherapy, which included cisplatin, doxorubicin, etoposide, and ifosfamide. Hence, the patient was discharged without any therapeutic regimen. The patient presented no deteriorative signs at the 6-month follow-up. Back to Top | Article Outline 3 Discussion and conclusion Orbital tumors in children can rapidly develop and lead to vision loss, and are associated with significant risk of mortality and morbidity.[6] Neuroblastoma is an undifferentiated malignant tumor that commonly occurs in children, which can rapidly metastasize and widely spread, resulting in a variety of clinical manifestations, such as proptosis, periorbital ecchymosis, abdominal pain, anemia, pancytopenia, bone pain, and paralysis.[7] In the present study, we present a case of a 3-year-old girl with stage IV neuroblastoma, who presented with periorbital ecchymoses and proptosis as initial symptoms. The diagnosis of neuroblastoma was confirmed by radiological analysis of the orbital tumors and an abdominal mass in the adrenal gland, as well as the characteristic histological findings of neuroblastoma. Since clinical manifestations and imaging features are not specific or defined for neuroblastoma, it remains difficult to differentiate neuroblastoma with orbital involvement from other metastatic orbital tumors, such as malignant lymphoma, rhabdomyosarcoma, granulocytic sarcoma, and Wilms tumors. Relevant literature was reviewed, and 10 cases of neuroblastoma with orbital involvement were found by searching PUBMED for published articles between 2000 and 2017 (Table 1). The clinical manifestations, radiological findings, and histological features of these cases, as well as the present case, were summarized (Table 1), which are integral to the clinical diagnosis and differential diagnosis of neuroblastoma with orbital involvement. Table 1 Periorbital ecchymoses and proptosis have been reported to be classic signs of pediatric neuroblastoma.[4,8] Consistent with these symptoms, it was found that the most common clinical manifestation of neuroblastoma with orbital involvement reported in the literature was periorbital ecchymoses (8/11, 72.7%), followed by proptosis (6/11, 54.5%; Table 1). The emergence of periorbital ecchymoses is probably due to tumor obstruction of the blood vessels in and around the orbits. Less common ophthalmic manifestations include periorbital swelling/edema (5/11, 45.4%), subconjunctival hemorrhage (2/11, 18.2%), vision loss (2/11, 18.2%), and decreased ocular mobility (1/11, 9.1%). Other uncommon clinical associations include pancytopenia, anemia, abdominal pain, fever, vomiting, and hepatosplenomegaly, which may be associated with the metastasis of the tumor to the bone or other organs. Since orbital neuroblastoma metastasis presents with non-specific clinical manifestations, it is often misdiagnosed as child abuse, orbital fracture, or other tumors such as rhabdomyosarcoma. CT and MRI can provide valuable diagnostic information for neuroblastoma identification, especially for pin pointing the primary site of the tumor. A giant hypoechoic mass with hyperechoic areas is the most common abdominal sonographic finding,[16] which was observed in the present case. With the exception of case 11, abdominal CT and/or MRI scans were performed in all of the cases reviewed, and abdominal masses in the adrenal gland were often discovered. The radiographic findings in the orbits usually included thickened bones, periosteal reactions (speculated bones), and lytic defects. In the MRI scans, neuroblastomas usually present with heterogeneous low signal intensity on T1-weighted images and high signal intensity on T2-weighted images.[6] The histopathological analyses of biopsied orbital masses were often performed to confirm the diagnosis of orbital neuroblastoma metastasis. The histological staining of the biopsied tissues revealed small round cells with a scanty cytoplasm and darkly stained nuclei.[9,12] Moreover, neural markers, such as neuron-specific enolase, TH, and synaptophysin, were often immunopositive in the tumor tissues, while S100 and leukocyte common antigens were immunonegative (Table 1).[12] The present patient refused any therapeutic regimen. At present, the primary treatment for neuroblastoma is chemotherapy. Multiple protocols with various agents, including carboplatin, vincristine, etoposide,[8] cisplatin, doxorubicin, cyclophosphamide, and ifosfamide,[12] are presently available. Other combined therapeutic strategies include 13-cis-retinoic acid,[9] local radiation, resection of the periorbital tumor, and autologous hematopoietic stem cell transplantation. However, in case of more aggressive tumors, drug resistance should be resolved in the future. Targeting techniques by infusion of meta-iodobenzylguanidine conjugated to 131I and 125I are also promising for future developments.[17] The prognosis for children with neuroblastoma is dependent on many factors, such as age at diagnosis, disease stage, and histological grade. Orbital neuroblastoma metastases are commonly associated with poor prognosis.[4] Among the 11 cases with orbital neuroblastoma metastases, systemic chemotherapy was initiated in 6 cases. Although the symptoms improved by follow up after 4 months to 2 years in 4 patients, 2 children died after chemotherapy. Furthermore, although the survival chances for children diagnosed with neuroblastoma have markedly improved over the last 30 years with the advance of multiple treatment modalities, such as chemotherapy, surgery, stem cell transplantation, and immunotherapy,[2] the survival rate for patients with neuroblastoma with orbital metastasis remains low. Back to Top | Article Outline Author contributions Conceptualization: Wan-Ju Yang, Yuan-Yuan Zhou, Shuang Li, Yi Xiang. Data curation: Wan-Ju Yang, Yuan-Yuan Zhou, Fang Zhao, Zhong-Ming Mei, Shuang Li, Yi Xiang. Investigation: Wan-Ju Yang, Yuan-Yuan Zhou, Fang Zhao, Zhong-Ming Mei, Shuang Li, Yi Xiang. Project administration: Wan-Ju Yang, Yuan-Yuan Zhou, Shuang Li, Yi Xiang. Resources: Wan-Ju Yang, Yuan-Yuan Zhou, Fang Zhao, Zhong-Ming Mei, Shuang Li, Yi Xiang. Supervision: Wan-Ju Yang, Yuan-Yuan Zhou, Shuang Li, Yi Xiang. Validation: Wan-Ju Yang, Yuan-Yuan Zhou, Fang Zhao, Zhong-Ming Mei, Shuang Li, Yi Xiang. Visualization: Wan-Ju Yang, Yuan-Yuan Zhou, Fang Zhao, Zhong-Ming Mei, Shuang Li, Yi Xiang. Writing – original draft: Wan-Ju Yang, Yuan-Yuan Zhou, Fang Zhao. Writing – review & editing: Wan-Ju Yang, Yuan-Yuan Zhou, Fang Zhao, Zhong-Ming Mei, Shuang Li, Yi Xiang.Back to Top | Article Outline References [1]. Bernstein ML, Leclerc JM, Bunin G, et al. A population-based study of neuroblastoma incidence, survival, and mortality in North America. J Clin Oncol 1992;10:323–9. Cited Here... [2]. Gutierrez JC, Fischer AC, Sola JE, et al. Markedly improving survival of neuroblastoma: a 30-year analysis of 1,646 patients. Pediatr Surg Int 2007;23:637–46. Cited Here... [3]. Kim S, Chung DH. Pediatric solid malignancies: neuroblastoma and Wilms' tumor. Surg Clin North Am 2006;86:469–87. xi. Cited Here... [4]. Smith SJ, Diehl NN, Smith BD, et al. Incidence, ocular manifestations, and survival in children with neuroblastoma: a population-based study. Am J Ophthalmol 2010;149:677.e2–82.e2. Cited Here... [5]. Bay A, Faik Oner A. Raccoon eyes. Indian Pediatr 2005;42:949. Cited Here... [6]. Rao AA, Naheedy JH, Chen JY, et al. A clinical update and radiologic review of pediatric orbital and ocular tumors. J Oncol 2013;2013:975908. Cited Here... [7]. Kalaskar RR, Kalaskar AR. Neuroblastoma in early childhood: a rare case report and review of literature. Contemp Clin Dent 2016;7:401–4. Cited Here... [8]. Cliff JF, Newman L, Malone M, et al. Facial features of widespread neuroblastoma: a case report. Int J Paediatr Dent 2001;11:215–20. Cited Here... [9]. Varma D, George N, Livingston J, et al. Acute visual loss as an early manifestation of metastatic neuroblastoma. Eye (Lond) 2003;17:250–2. Cited Here... [10]. Gumus K. A child with raccoon eyes masquerading as trauma. Int Ophthalmol 2007;27:379–81. [11]. Moran DE, Donoghue V. Periorbital ecchymosis ('raccoon eyes') as the presenting feature of neuroblastoma. Pediatr Radiol 2010;40:1710. [12]. Salmi D, Patel C, Imashuku S, et al. Neuroblastoma of unknown primary site with periorbital bone metastasis in a child. Pediatr Blood Cancer 2010;55:361–3. Cited Here... [13]. Muniz AE. Metastatic neuroblastoma: the mimicker of basilar skull fracture in children. J Emerg Med 2012;42:e19–21. [14]. Ghosh SK, Dutta A, Basu M. Raccoon eyes in a case of metastatic neuroblastoma. Indian J Dermatol Venereol Leprol 2012;78:740–1. [15]. Kurian J, Chen NN, Shinder R. Orbital metastatic neuroblastoma. Ophthalmology 2016;123:1674. [16]. White SJ, Stuck KJ, Blane CE, et al. Sonography of neuroblastoma. AJR Am J Roentgenol 1983;141:465–8. Cited Here... [17]. Haase GM, Perez C, Atkinson JB. Current aspects of biology, risk assessment, and treatment of neuroblastoma. Semin Surg Oncol 1999;16:91–104. Cited Here... Keywords:adrenal tumor; case report; neuroblastoma; orbital metastasis Copyright © 2019 the Author(s). Published by Wolters Kluwer Health, Inc.

subset: commoncrawl


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Last week, the Garden Guru mentioned that it's time to bring in your houseplants that have been living outdoors for the Summer!
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1. Dainik Navjyoti
Case registered against man for threatening a woman with killing her children and raping her
2. Dainik Navjyoti
Women's organizations in Jaipur organizing a fortnight to highlight the problem of violence against women
3. Hindustan Times
In foetus sex determination racket, tip-off to officials of PC-PNDT district cells gets leaked. District Chief Medical and Health Officers are secretaries of these cells.
4. Dainik Bhaskar(Udaipur)
Bail denied to five persons accused of storming into a house and beating and injuring women
5. Dainik Bhaskar(Udaipur)
Man convicted for assaulting a Dalit woman after tying her with a tree sentenced to two years' imprisonment
6. Rajasthan Patrika(Kota)
Man convicted for abducting and raping an adolescent girl seven years ago gets seven years in jail
7. Rajasthan Patrika(Udaipur)
Women to get free-of-cost treatment under a project financed by European Commission


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Good Bad Ideas That's So GCSE
Blackouts. Chair duets. Overacting. Brecht. Watch these students navigate the GCSE Theatre curriculum to perform a stunning show of their combined pubescent talents, in this hilarious new comedy, showcasing the fond memory of amateur and GCSE Theatre.
This show was part of our 2018 Edinburgh Fringe Programme


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Spongeball Billy: Stories comes with 3 short narrated stories about SpongeBall Billy, 9 coloring pages and 3 game/activities, all for free!
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Professor Annette Kuhn FBA
About this Fellow
Annette Kuhn is Professor and Research Fellow in Film Studies at Queen Mary University of London, a Fellow of the British Academy, and a Member of the European Academy. Her previous academic posts were at the Institute for Cultural Research at Lancaster University and in the Department of Theatre, Film and Television Studies at the University of Glasgow. She holds degrees in Sociology at the Universities of Sheffield and London and has held Fellowships and Visiting Professorships at the Australian National University's Humanities Research Centre, at Mount Holyoke College (as Fulbright Senior Research Scholar), and at Stockholm University. She was an editor of the journal Screen, directed the ESRC-funded project 'Cinema Culture in 1930s Britain', and convened the Transitional Phenomena and Cultural Experience study group. She writes on film history, and on cultural memory in relation to photography and cinema. Publications on cultural memory include An Everyday Magic: Cinema and Cultural Memory (2002); Family Secrets: Acts of Memory and Imagination (2002); Locating Memory: Photographic Acts (2006, co-edited with Kirsten Emiko McAllister); and a special issue of Memory Studies on cinemagoing experience and memory (2017, co-edited with Daniel Biltereyst and Philippe Meers). She is co-author with Guy Westwell of the Oxford Dictionary of Film Studies (2012) and is currently working on a second edition. She is on Twitter at @AnnetteKuhn7.
Website: https://www.qmul.ac.uk/sllf/film-studies/people/academic/profiles/kuhn.html
Current post
- Professor and Research Fellow in Film Studies, Queen Mary University of London, 2014 -
Past Appointments
- Senior Professorial Fellow, School of Languages, Linguistics and Film, Queen Mary, University of London, 2006 - 2013
- Professor of Film Studies, Institute for Cultural Research, Lancaster University, 2000 - 2006
- Reader in Cultural Research , Institute for Cultural Research, Lancaster University , 1998 - 2000
- Reader in Film and Television Studies, Dept of Theatre, Film and Television Studies, University of Glasgow , 1991 - 1998
- Lecturer in Film and Television Studies, Dept of Theatre, Film and Television Studies, University of Glasgow , 1989 - 1991
British Academy Appointments
- CMP Standing Committee, 2019 -
- Art Committee, 2015 -
- Modern Languages, Literatures and other Media from 1830 Standing Committee Member, 2006 - 2009
- Modern Languages, Literatures and other Media from 1830 International Fellowships Officer , 2011 - 2015
Top picks
Family Secrets: Acts of Memory and ImaginationAnnette Kuhn, 1995 Verso Books
Revised edition published in 2002
Little Madnesses: Winnicott, Transitional Phenomena and Cultural ExperienceAnnette Kuhn, 2013 I.B. Tauris
Other Culture, Media and Performance Fellows
Professor Dame Marina Warner
History; historical studies of language and literature; English language and literature
Professor Lisa Tickner
History of British art in the late 19th and 20th centuries, including the imagery of the suffrage campaign, early 20th-century British modernism, art education, and the London art world in the 1960s.
Professor Felix Driver
Historical geography of British empire & exploration, eighteenth to twentieth centuries; histories of collecting, visual culture & geographical knowledge
Professor Laura Marcus
Nineteenth & twentieth century literature & visual culture; early film & literature, Virginia Woolf & Bloomsbury culture, modernism, life-writing


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Rebecca L. Palmer
Name: Rebecca L. Palmer
Directory: Legal Directory
Rebecca Palmer has extensively practiced in the area of Family and Marital Law. She has a broad background in providing alternative dispute resolution, general litigation, and collaborative law issues for domestic disputes. Rebecca's matters range from pre-marital agreements, divorce, and adoptions. Rebecca is a Supreme court Family Mediator.
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Listing Title: Rebecca L. Palmer


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Important Note
Be sure to check the Product Availability List (PAL) in your Back Office under "News from the Nest" every day for the latest updates on all the other items in the collection.
Be sure to go to your My O2 Connection app and search for "Wizard of Oz" to share Warner Bros-approved social media images and share the good news with your Customers!


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The small amount of plasmin generated by the activity of the one-chain form of urokinase plasminogen activator in turn cleaves urokinase plasminogen activator, converting it to its substantially more active two-chain form (Cubellis et al. 1986; Lijnen et al. 1991).
Lijnen, HR,
Zamarron, C,
Blaber, M,
Winkler, ME,
Collen, D
Cubellis, MV,
Nolli, ML,
Cassani, G,
Blasi, F
© 2019


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I'm still trying to use up all the odds and ends in my kitchen, I went for a light, breakfast-y, cranberry-cornmeal cake. I started by following a Giada recipe, but halfway through realized that it used dried cranberries, so I made a few quick substitutions and crossed my fingers. And it worked! The cake was moist, flavorful, and well balanced. I might reduce the sugar by 1/4 cup when I make it again, but other than that, a winner.
Cranberry Cornmeal Cake
Serves 8-10. Original recipe.
- 1 1/2 sticks butter, room temperature
- 1 3/4 c. sugar, divided
- 1 tsp. vanilla
- 2 whole eggs
- 2 egg yolks
- 2 c. fresh or frozen cranberries
- 1 c. AP flour
- 1/2 c. fine cornmeal
- 1 tsp. baking powder
- 1/4 tsp. salt
- Preheat oven to 350°F. Grease and flour a 9 inch round cake pan.
- In a large bowl, cream together butter and 1 1/4 cups of the sugar until pale and fluffy. Add vanilla and stir to incorporate. Add eggs and egg yolks one at a time and stir to incorporate.
- In a medium bowl, whisk together flour, cornmeal, salt, and baking powder. Fold into wet ingredients in two batches.
- In a food processor, briefly pulse cranberries and remaining 1/2 c. sugar, until cranberries are in small pieces but not pureed. Gently stir cranberries into batter, then spoon into pan and smooth with a spatula. Bake for 50 to 55 minutes until a toothpick inserted into the center of the cake comes out clean, and the top of the cake is golden brown.


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Organizing Committee
Cathleen McCabe, MD is one of the foremost eye surgeons practicing today and is a vital asset to The Eye Associates' team, seeing patients in Sarasota, Bradenton and Ellenton, Florida. After Dr. McCabe received her medical degree from the Medical College of Wisconsin, she went on to her residency training at the prestigious Bascom Palmer Eye Institute of the University of Miami's School of Medicine. Dr. McCabe specializes in bladeless laser cataract surgery, clear lens replacement, LASIK and anterior segment diseases. Cathleen McCabe has received many prestigious and esteemed awards for her work in Ophthalmology, including being named a Castle Connolly Top Doctor for Ophthalmology and to the Premier Surgeon 250 List of the leading innovators in premium IOL cataract surgery, and was selected as a LaserVision Top 100 Surgeon for her vast experience and excellent outcomes in LASIK and refractive surgery. Dr. McCabe's other achievements and awards include being named an Outstanding Female Leader in Ophthalmology by Millenial EYE magazine, the recipient of the American Academy of Ophthalmology (AAO) Achievement Award, and she was one of only four surgeons invited to perform LIVE cataract surgery at Texas Eye and Surgery Center in Hurst, Texas, which was telecast in real time to 1000 MDs attending the Alcon event from all over the world. Dr. McCabe's ongoing commitment to continuing her education earned her the Physician's Recognition Award (PRA), presented by the American Medical Association, and she has also been honored with the Lifelong Education for the Ophthalmologist (LEO) Continuing Education Recognition Award by the American Academy of Ophthalmology. Dr. McCabe was granted membership into the American College of Eye Surgeons (ACES) because of her commitment to excellence in eye surgery. She has also successfully fulfilled the requirements for Maintenance of Certification (MOC) to be recertified as a Diplomate of the American Board of Ophthalmology. Cathleen McCabe is a Board member of the Outpatient Ophthalmic Surgery Society, the Vice Chairman and a member of the Practicing Ophthalmologists Curriculum Panel (POCP)- Cataract and Anterior Segment Panel and a Board Member of the Outpatient Ophthalmic Surgery Society. Dr. McCabe also serves on the Editorial Board for Ophthalmic ASC, EyeNet, and Cataract and Refractive Surgery Today publications. Additionally she continues to share her expertise by publishing articles and book chapters, lecturing at ophthalmological and optometric seminars all over the country, and participating in residency training programs.
Research Interest
Cataract, Refractive, and Advanced Lens Technology
Nikolakopoulos Athanasios Born and resident of Thessaloniki, Greece. He is Graduated from the Aristotelio University (Greece)–Medical Department. He did his postgraduate studies (fellowship) at the Hospital of Addenbrook Cambridge England on the retina diseases with Mr J.D.Scott, on glaucoma with Mr J.D.Cairns and on inflammations with Mr P.Watson. Attended Moorefield Eye Hospital on Lasers in Ophthalmology and on the retina surgery of Giant tears. Attended the Rotterdam Clinic Center with Rellyo Zivojnoviz, as a representative of the Cambridge Hospital. He is also senior registrar at Adenbrooks Hospital, organized and directed the Retina department of St.Dimitrios Hospital of Thessaloniki and he became Director of Retina clinic of St.Dimitrios Hospital. Nikolakopoulos Athanasios was the former president of the Greek Ophthalmological Federation and The Greek Vitreoretinal Society.
Research Interest
Glaucoma and vitreoretinal surgery
Felipe Soria studied Medicine in the Adventist University in Argentina and did his specialty in Ophthalmology in the Vision Institute of Montemorelos University in Mexico. He made the subspecialties of Cornea, Refractive and Cataract surgery in Vissum Corporation with Dr. Jorge Alio for a period of two years.
He has written more than 30 scientific articles and book chapters, being Editor of the book Femtosecond Laser Assisted Keratoplasty.
He has participated with 40 communications in different international congress across the world.
He owns the patent: Use of Mesothelial cells in Tissue Bioengineering and Artificial Tissues.
Interview for EyeWorld TV: http://ewreplay.org/node/555?v=3784727216001
Research Interest
Cornea, Refractive and Cataract surgery
Cristian Falcon is the Director of Optima Laser Clinic, Valencia, Spain and member of reputed ophthalmology societies. He is an Ophthalmology surgeon specialist in Refractive surgery: LASIK, SBK, Intraocular lenses and phacoemulsificaion. He is having an extensive experience in LASIK, SBK and LASIK(SBK) for Presbyopia & performed 12,000 procedure over this years of practice. He has published his research papers in various reputed journals and he is been invited in many scientific conferences around the world as a speaker.
Research Interest
LASIK, SBK and LASIK(SBK) for Presbyopia
Jacob Lorenzo-Morales completed his PhD in the University of La Laguna in 2001 and held postdoctoral positions at the University of Edinburgh until December 2011 when he was granted a Ramón y Cajal Tenure Track Fellowship by the Spanish Government. His work has been focused in Free-Living Amoebae infections mainly Acanthamoeba keratitis. He has published more than 60 papers in reputed journals in the parasitology and tropical medicine fields. He has been the Scientific Secretary in the last two editions of the International free-living amoebae meetings (FLAM 2009 and 2011), invited speaker at the symposium of free-living amoebae of the International Congress of Parasitology 2014. In November 2013 he was awarded the Individual Award for Young Canary Islands Citizens by the Canary Islands Government in recognition to his research career.
Research Interest
Contact lens, Ocular diseases
Baswati Prasanth, Specialist Ophthalmology has 10 years of vast experiences from various hospitals in India and other countries, completed her MS Ophthalmology from Armed Forces Medical College, Pune and Fellowship in Glaucoma and Anterior segment from Dr Shroffs Eye Hospital, New Delhi. She is the winner of A D Patwardhan Gold medal from university of Pune. She is the Director of Ophthalmology, Ahalia hospital, Abudhabi. She has published more than 15 papers in reputed journals and has been part of several clinical trials.
Research Interest
Phacoemulsification, small incision cataract surgery, glaucoma surgery
Miguel Rechichi has completed his training in ophthalmology at 28 and his PhD at 32 from Magna Graecia University and Diploma of Specialist Superior in Ophthalmology from University of Lugano (Switzerland). He's actually a researcher for Magna Graecia University and Director of corneal and refractive Surgery service of S.Lucia Eye Clinic, Cosenza, Italy. He was a pioneer of crosslinking clinical application and actually is involved in developing new accelerated cxl protocols for which he's invited as opinion leader to several meetings. He has published several papers in reputed journals and has been serving as an editorial board member of reputed Journals.
Research Interest
Optical Coherence Tomography, Cornea
George Beiko is a medical graduate of Oxford University and completed his ophthalmology specialty training at Queens University in Canada. He is an Assistant Clinical Professor at McMaster University and a Lecturer at the University of Toronto. Dr. Beiko has published numerous peer-reviewed articles and also authored twelve book chapters. He has given over 500 scientific presentations at meetings throughout the world. He has been awarded 3 best papers of session at the ASCRS annual meeting, one best poster award at AAO, one Best Paper of Session (Cataract) at APAO-AAO Joint Meeting and the Best Original Paper in Cataract Surgery at AAO in 2010. He is on the review panel or editorial board of 25 ophthalmology journals. His honours include being elected to membership in the International Intraocular Implant Club, being named one of the "Premier Surgeons" of North America and being made an Officer of the Most Venerable Order of the Hospital of St. John of Jerusalem, by Her Majesty The Queen of England. He has been honoured on 3 occasions with the Gold Medal by the Indian Society of Cataract and Refractive Surgery, a Senior Achievement award by the American Academy of Ophthalmology, an Achievement Award by the Asia Pacific Academy of Ophthalmology, the Presidential Award of the International Society of Refractive Surgery and the Boberg-Ans Award of the Danish Ophthalmological Society.
Research Interest
Supriyo Chatterjee is an educator and a practitioner in Optometry since 1990. He completed his Bachelor's degree in Human Physiology from Calcutta University and thereafter completed his 4 year PG Diplomas in Optometry and Contact Lens Practice from Indian Optical Institute& Refraction Hospital (Estd.1932), the pioneer Institute of Optometry in India, Calcutta. He went to USA for advanced studies and clinical internship in California under Optometric Extension Program Foundation and State University of New York – College of Optometry, in the areas of Binocular Vision, Pediatric Optometry and Behavioral Optometry. He was an Associate of College of Optometrists in Vision Development of USA and Clinical Associate of Optometric Extension Program Foundation, California. He has presented many papers in home on Behavioral Optometry, Sports Vision, Myopia, Near point Vision Stress, Non Strabismic Binocular Dysfunction and Vision Therapy. He was awarded Bausch & Lomb Certificate of Excellence in Contact Lens Practice as well as Silklens India Award for Outstanding Contribution to Optometry Education in Eastern India. He also represented India, particularly his Alma Mater in 4th World Council of Optometry Educators' Meet in Atlanta, Georgia in 2002, as the Director of Academic Affairs of the AII India Institute of Optometrical Sciences (AIIOS). He was selected by ORBIS International, Ethiopia to serve as an Assistant Professor of Optometry, Department of Ophthalmology, College of Medicine & Health Sciences, University of Gondar, Ethiopia in 2008. His areas of interest are: General & Pediatric Optometry, Infant Vision Development, Non-Strabismic Binocular Dysfunctions, Myopia, Computer Vision Syndrome, Sports Vision, Ocular Pathology & Therapeutics, Vision Therapy and Neuro-Optometry.
Research Interest
General & Pediatric Optometry, Infant Vision Development, Non-Strabismic Binocular Dysfunctions, Myopia
Chris (tiane) Lange-Küttner obtained her Ph.D. at the Max Planck Institute of Human Development, Berlin, and worked thereafter as a post-doc in Cognitive Science at the Free University of Berlin. Since 1994, she holds an academic faculty position in the UK, initially at the University of Aberdeen, and up to now at the London Metropolitan University. From 2009-2011 she was Professor of Developmental Psychology at the University of Konstanz, Germany. She is also affiliated faculty at the University of Bremen, Germany.
Research Interest
Perspective Mapping, Psychology


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Bonakdaran, Shokoufe and Akbari Rad, Mina and Hasanzadeh Deloie, Mahdi and Akhoondpoor manteghi, Mahdi and Firoozi, Abdollah (2017) Pediatrican and pediatric residents� knowledge about anaphylaxis in teaching hospitals of Tehran University of Medical Sciences. medical journal of mashhad university of medical sciences, 60 (2). pp. 441-449.
MJMS_Volume 60_Issue 1_Pages 359-368.pdf
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Background: Methadone is used for controling the chronic pain and treatment of opioid addiction. Prolonged QTc is a known cardiac complication of this drug. It seems that many factors affect the QT interval in methadone users. Several reports have suggested the role of sex hormones in QT prolongation. The objective of this study was to evaluate the effects of methadone in QTc prolongation in methadone users in comparison with healthy control groups and its relation with hormonal changes . Subjects&Methods:  We selected 40 addicted patients who had used methadone as their opioid withdrawal for at least 6 months against 40 random healthy volunteers. For all subjects, assessment of hormonal parameters and ECG were done and two groups were compared. Results: No significant changes were shown in hormonal parameters except to FSH. QTc interval was significantly higher in methadone users than healthy control group(455.75±63.2 vs 426.25±22.2). PR interval was significantly shorter in methadone users ( 139.00±36.22 vs 158.25±24.48 ). QTc had significant inverse relation with testosterone level (r=-0.58, P=0.007) . Conclusion: Prolonged QTc is an important complication of methadone that seems to be related to low testosterone level.Â
|Item Type:
|WA Public Health
|Journals > Medical J Mashhad University of Medical Sciences
|Depositing User:
|mjmums mjmums
|Date Deposited:
|27 Sep 2018 07:31
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|27 Sep 2018 07:31
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Business Owners Are Finding Better Ways To Fund Their Business With Working Capital Cash Flow!
The present business financing condition is as yet not good to the entrepreneur in getting endorsed for private company advances for working capital with no business resources and very little benefit. Business working capital subsidizing is a troublesome accomplishment in this present monetary state of our nation. As we as a whole know, business transient subsidizing enables entrepreneurs to acquire business subsidizing for their business to make due through any monetary crunch that surfaces for elective financing. This article will talk about the best tips for getting quick, simple business subsidizing for working capital for basic day by day income required by the entrepreneur. clickfunnels pricing
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A promising business with critical measure of bank stores and dependability will get quick bank articulation financing within 72 hours. The ability of picking a reimbursement plan which is for a present moment is an additional preferred standpoint of these loan subsidizing.
Business money financing has made it less difficult to get quick assets absent much issue regardless of whether the entrepreneur has been turned somewhere around their nearby bank. Anyway it is imperative to do legitimate research about the private bank before applying for these sorts of transient assets. The web is the chief alternative to recognize a dependable and mindful banks for business loans, checking with the BBB for any records that may show any protests documented against the moneylender. There are numerous online business loan banks so it can without much of a stretch be actually difficult to separate dependable ones to an online trick. Likewise offering the proprietor an excess of working capital at one time for that specific private company may really hurt the reimbursement of the subsidizing causing an income issue for the entrepreneur. The entrepreneur must discover a loan specialist who will look out for the main concern of the entrepreneur.


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We want to share some of the amazing creators, products and companies we came across at the Mindful Living Show, as it can be so helpful to have products and organisations in your life that can help with sleep, relaxation, meditation, yoga, anxiety and stress. There were many great exhibitors and groups, but here are a few of our favourites.Read More
At HERE, our goal is to create happy, healthy households worldwide through mindful practice. From stress to mental health issues, families are in critical need of wellbeing support and resources are lacking. One way in which we aim to introduce mindfulness to families is through our Om:Pop… We would love to have your support to bring more Om:Pops to London!Read More
We love Yoga Pretzels as a mindful activity for children. Research shows that yoga benefits children greatly when it comes to easing stress, anxiety and pressure. It's also a great activity they can do with friends and parents! Don't take it from us, hear about it from them!Read More


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Top Part time LLM Degrees in Civil Law Studies in the Victoria Australia 2019/2020
The Master of Laws degree commonly known as the LL.M., is an advanced graduate law degree. Candidates often already hold a first degree in law and are interested in furthering their studies of the law. Obtaining an LL.M. possesses a number of distinct advantages.
Part time LLM Degree in Civil Law Studies in the Victoria in Australia
1 Results inCivil Law Studies, Victoria Filter
Master of Public and International Law
Melbourne Law School
Campus Full time Part time 1 - 4 years Request Info Australia Melbourne + 1 more
The Melbourne Law Masters is a graduate law program of the highest quality, available to law and non-law graduates. The specialization in public and international law brings together constitutional, administrative and public international law in recognition of the increasing interdependence of international and domestic law.


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Grand Palace Condos
The sellers of this condo was hoping for a quick sell, and they enlisted our staging services to speed up the process. From staging consultation to staging to getting sold, all WITHIN a week's time. We try our best to work with our client's timing. Contact us now!


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2 Piece Prom Dresses 2019
- two piece Sleeveless Floor-length Dress With Lace top
- Long-Sleeves Satin Ball-Gown Princess Floor-Length Bateau-Neck Dress
- Jewel-Neck Sleeveless Lace Two Piece Prom Dress With Appliques And Sweep Train
- Sheath jewel-neck sleeveless Jersey two piece Dress With Lace And Sweep train
- Beadeded Two-Pieces Inspire High-Neckline Glamorous Formal Dress
- Mermaid Bateau Sleeveless Satin Two Piece Prom Dress With Lace top
- Sleeveless Mermaid Two Piece Prom Dress With Beading And Lace
- Off-the-shoulder Pencil Knee-length Dress With Lace And Peplum
- Bateau Sleeveless Jersey Prom Dress With Beading And Illusion
- Beaded Bateau-Neck Sleeveless Formal Jersey Dress
- formal V-neck Half Sleeve Pencil Satin Knee-length Dress With jacket
- Short Cocktail Tulle Keyhole Mini A-Line Beaded Sleeveless High-Neck Dress
- A-Line Jeweled-Bodice Tulle Crop-Top Sleeveless Bateau-Neck Formal Dress
- Short Cocktail Tulle Mini A-Line V-Neck Crystal Sleeveless Dress
- V-Back Sequined Cap-Sleeve 2-Piece Lace Column Formal Dress
- 2 Homecoming Mini Glimmering-Bodice Piece Sleeveless Tulle Jewel-Neck Short Dress
- Cap-Sleeve Tulle Skirt Jeweled Top 2-Piece Mini Homecoming Dress
- A-Line Long Sleeveless Beaded Tulle Prom Dress With Pleats
- 2-Piece Illusion Satin Appliqued A-Line Full-Length Short Jewel-Neck Mini-Sleeve Dress
- Scoop-neck Long Sleeve Illusion A-line Satin Two Piece Prom Dress
- 2-Piece Bling Bust Sleeveless Chiffon Mini Short Homecoming Dress
- Low-V Back Bodice And Lace Skirt Prom Dress In Two Pieces
- Prom Rhinestoned Tulle A-Line Two-Pieces Gorgeous Dress
- Two-Piece Off-The-Shoulder A-Line Lace Sassy Gown
- A-Line Ruffled Sleeveless Floor-Length Tulle Gown
- Rhinestoned Two-Piece Tulle Halter Lovely Cocktail Short Dress
- Short Rhinestoned Sleeveless Halter Sassy Gown
- 2-Piece Tulle Sleeveless Jeweled Multi-Color A-Line Mini Short High-Neck Dress
- Sleeveless Rhinestone High-Neckline A-Line Lace Tulle Gown
- 2-Piece Ruffled Beaded A-Line Short Jewel-Neck Mini Sleeveless Dress
- A-Line Satin Tulle Beaded Short Mini Short Jewel-Neck Mini-Sleeve Dress
- A-Line Jeweled Appliqued Short Mini Sleeveless High-Neck Dress
- A-Line Illusion Beaded Ruffled Short Mini Sleeveless Jewel-Neck Tulle Dress
- 2-Piece Jeweled Split Front Column Scoop-Neck Jersey Sleeveless Illusion Dress
- A-Line Jeweled Mini High-Neck Satin Sleeveless Dress
- 2-Piece Illusion Tulle Ruffled Appliqued A-Line Short Scoop-Neck Mini Sleeveless Dress
- Crop Top Lace Skirt A-Line Prom Dress With Bateau Neck And Beadwork
- Gorgeous Beadings Sleeveless Prom Dress 2018 Long Chiffon Party Gowns
- Prom Jewels Ruffle Two-Pieces Halter Glamorous Dress
- A-Line Keyhole Jeweled Appliqued Short Mini Cap-Sleeve Scoop-Neck Tulle Dress
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- High-Neckline Rhinestoned Short A-Line Tulle Dress
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2 Piece Prom Dresses 2019
CUSTOMER REVIEWS (13)2 Piece Prom Dresses 2019
By Emily Tiffany
Oct 17,2019
This seller is AMAZING!!! Works hard to help answer all questions and helps customize what you need!!! So quick and great quality!!! I could not have my dream dress without her!!! She is so patient and so kind!!!
By Laura Bruce
Oct 06,2019
Shipping was incredibly fast and the shop was very prompt and nice when replying to messages. The dress itself is absolutely beautiful. Overall I felt like the shop owner was friendly and responsive. Just what I needed. Beautiful with my dress!
By Melissa Draper
Sep 30,2019
I am extremely happy with the lace dress, shipping was very fast (live in AZ). The color is beautiful, I was a little surprised about the weight and the dress fabric was so comfy. I'm happy. Think I'll be buying another style soon.
By Kaylashay
Sep 15,2019
So simple yet elegant. Beautiful two piece dress and nicely packaged ! Just what I was looking for and SO affordable. Very fast shipping! Thank you!!
By cutsiegirl
Sep 07,2019
The quality is great and perfect! I love the color of the black, definitely looks like the picture of the girl wearing it! I did not order swatches before hand because I did not have to match anything important so I was very happy! Overall, very high quality products and would love to have other colors! I am 5'2' and got the 42inches length and it is too long so I will need to have it hemmed, just for anyone who is the same height as me so you know.
By Cindy Roz
Aug 25,2019
Amazing! I can't say enough about the services, attention to detail and patience with my VERY last minute order. Thank you SO much!
By krystalbishop92
Jul 24,2019
Thank you so much! Super fast shipping and gorgeous dress! I absolutely love the lace top on this dress! Love my dress and can't wait to wear it. Many Thanks - received and happy!
By Samantha Lednick
Jul 16,2019
This dress is beautiful! I can't wait to wear it to every event this summer. The dress took the full three weeks (busy season) plus shipping time to arrive but it is worth it. The floral lace fabric is nice, it is Wonderful craftsmanship, as always!
By roiovtch
May 10,2019
This dress got to me very quickly. The lace was beautiful but the material was a bit thick, but, it was a very pretty dress! cant wait to wear it!
By mrcircles1
Apr 21,2019
Love this dress, It's exactly the color I expected and very beautiful and comfortable. Will be wearing it soon for a special event.
By Imani Jabali-Vaughn
Mar 19,2019
I absolutely LOVE the color, fit of this dress!! I will be sure to send a picture once I wear it :)
By Marcy Matthews
Jan 17,2019
Beautiful dress! I love the quality and am so happy I purchased! Arrived within a few days of ordering!
By Kristen Dickey
Dec 23,2018
So grateful for how much the shop was able to work with me to order this dress for my sister! She loves it! Quick shipping, as always great communication .. Thank you for all of your help.
- View more


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If you're suffering from digestive woes (gas, bloating, reflux, constipation), try rotating this morning porridge into your breakfast routine.
The gut needs fiber and mucilage to function optimally and this breakfast cereal contains both; fiber from the oats and fenugreek seeds and mucilage from the slippery elm and flax seeds.
Grains, like oats, needs to be processed properly and that means soaking them.
I soaked the oats in an acid-medium (goat kefir) to neutralize the anti-nutrients, and make the oats way more beneficial to health.
If you find that the kefir makes the oats taste too sour, you can sweeten this porridge with honey or maple syrup. If you don't use eat dairy, you can use any other acid medium (vinegar, lemon juice).
And, if you simply do not like oats, you can swap them out and use any other cooked grain instead (brown rice, cracked wheat, quinoa, or buckwheat). If you use another type of grain other than oats, make sure it is pre-cooked. Rolled oats are pre-cooked (steamed).
Enjoy this gut-healing porridge and send your belly some fiber, mucilage and love!
- 1 cup rolled oats (or 1 cup cooked rice)
- 2 cups water
- 1 tsp. fenugreek seeds
- ¼ tsp. ground cinnamon
- ½ cup fresh berries (or ¼ cup dried)
- 1 tsp. slippery elm powder
- ¼ tsp. sea salt
- 2 tsp. ground flax seeds
- 3 tbsp. yogurt, or kefir
- Put oats, 1 cup water, fenugreek and 1 tbsp. yogurt or kefir into a pot.
- Sit covered overnight.
- In the morning, add remaining 1 cup water, cinnamon, berries, slippery elm, water and sea salt.
- Bring to a boil.
- Lower to simmer and cook 5-7 minutes.
- Top with ground flax seeds and remaining kefir.
- Garnish with some fresh berries.
Andrea Beaman is an internationally renowned Holistic Health Coach, Natural Foods Chef, Speaker and Herbalist. Named one of the top 100 Most Influential Health and Fitness Experts, she is also a recipient of the Natural Gourmet Institute's Award for Excellence in Health-Supportive Education and a Health Leadership award from The Institute for Integrative Nutrition. Since 1999, Andrea has been teaching people how to harness the body's own preventative and healing powers using food, herbal remedies and alternative medicine.


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Board index » MFC
All times are UTC
 Hi.
I want start learning internet programming I'm beginner programmer at work i write in Visual C++ interface and some database (raely sux) i want study internet programming and
i need some point to books ,sites, faq ...
i want start with irc server i have a litle time for this:)))
thanks
1. programming language advice needed
2. Need advice on C program
3. need programming advice
4. Need Help/Advice With This C Program...
5. New to programming...advice needed!
6. Programming advice needed
7. Program freezes with Sleep() - now i need some advice about a multi-threaded app
8. Advice needed: Alternative make programs
9. Needing advice on Wav programming
10. New to DB programming, need to access database through the Internet
11. Advice on C++ Active X Control in Internet Explorer
12. Writing a program that can communicate with other programs on the Internet


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Public Safety Canada - Home
Sep 6, 2019 ...Careers @ Public Safety Canada Are you interested in helping to keep Canadians safe from a range of threats such as natural disasters, crime and terrorism? If so, Public Safety Canada may be the place for you! News Statement from Minister Goodale regarding Hurricane Dorian September 7, 2019 University of Regina project to address over-representation


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Regional Investigations Unit detectives have charged a man in relation to an armed robbery in Rivervale yesterday, Sunday 5 May 2019.
It will be alleged about 9.15am, the man armed with a knife entered a service station located on Great Eastern Highway. He threatened staff and demanded cash. When staff refused, he left the knife on the counter and left the store.
The man was located by police a short time later on Great Eastern Highway near Kooyong Road in Rivervale and taken into custody.
The 35-year-old man of no fixed address has been charged with Attempted Armed Robbery and he is due to appear before the Perth Magistrates Court today, 6 May 2019.


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Mary Zarei is a native of nearby Merogomish, NS who is now living in Sussex, NB where she and her husband are homeschooling their three children. An avid yoga instructor and long time fan of Pictou Island, Mary is guiding Yoga Retreat Yourself for the third year in a row!
Yoga Retreat Yourself
Four days with Mary Zarei
Two Sessions in 2019
July 28 - August 01 (sold out)
August 04 - August 08
Only 12 spots available for each session!
Four days of yoga, meditation, and energy work can't help but quiet and heal your mind, body, and spirit. Explore the strength and flexibility of your body and find the deep connection to an inner peace that lies within you. What better place to discover the gifts of movement, mindfulness, and relaxation but here on Pictou Island!
4 nights in a wooden tent (Sun - Thur)
8 Full yoga lessons
1 Full day bike rental
Transportation from the ferry
Single Occupancy … $385
Double Occupancy … $235
* HST must be added to these prices.


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#246 Under the Shade Bus with Maddie
Scott Benner
Maddie is a college student living with type 1 diabetes…
A simply delightful episode!
You can always listen to the Juicebox Podcast here but the cool kids use: Apple Podcasts/iOS - Pandora - Spotify - Amazon Alexa - Google Play/Android - iHeart Radio - Radio Public or their favorite podcast app.
Please support the sponsors
The Juicebox Podcast is a free show, but if you'd like to support the podcast directly, you can make a gift here. Recent donations were used to pay for podcast hosting fees. Thank you to all who have sent 5, 10 and 20 dollars!


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Published by Malaysiakini, images from Malaysiakini.
An alliance of Muslim nations may not have been raised by Prime Minister Dr Mahathir Mohammad in any specific form, yet it carries the potential to reshape the world order.
But it is clear that this inchoate idea had been in his mind for some time.
And it emerged in his conversation with Turkish President Recep Tayyip Erdogan, when Mahathir spoke of the importance of Malaysia, Pakistan and Turkey working hand in hand to reduce their dependence on the usual suspects in the world.
To the list, one must add Iran, Indonesia and Qatar. Three of the most strategic Muslim countries in the world.
Iran may be under sanctions from the United States, but it is now developing an alternative system of commercial payment with Russia and China to overcome American domination on the Swift banking system.
Pakistan is the "iron brother" of China, with a significant understanding of its internal politics. While Malaysia also understands this, it helps to have the help of Pakistan to overcome any imbroglio over the South China Sea.
Qatar is rich with liquefied natural gas. With China still very much dependent on coal, which increases its pollution problem, Qatar and Malaysia's rich reserves of LNG can reduce the superpower's energy consumption profile, thereby reducing the threat of climate change as well.
Indonesia is no less a major power and producer in LNG. It also plays a powerful role in the Indo-Pacific and the Straits of Malacca alongside Malaysia.
Turkey, in turn, controls the Bosporus which makes the US and Russia, and even China, France, the United Kingdom ever respectful of the country.
If there is an alliance of Muslim nations, what the world will see is nothing less than an Islamic version of the G6. Other Muslim countries have to be brought into this coalition as well to further strengthen it.
When Malaysia is in such an alliance, it can also depend on the membership of Indonesia in the G20 and the Organisation of the Petroleum Exporting Countries (Opec).
As long as Malaysia and Turkey, a sectoral partner of Asean, can imagine the above scenario in a comprehensive and strategic manner, there is no reason why the Islamic world has to be constantly at the whims and fancies of other external powers.
An alliance of Muslim nations could control all the major maritime chokepoints in the Straits of Malacca, Gulf of Oman, Strait of Hormuz, and the Bosporus.
Since maritime trade is three times cheaper than rail freight, the impact of the Muslim world would be significant on global commerce.
Together we stand, as Mahathir said at PKR's Port Dickson retreat last week, divided we fall.
What is valid in Pakatan Harapan is equally true in the world of Islam.
Dr. Rais Hussin is President & CEO of EMIR Research, a think tank focused on data-driven policy research, centered around principles of Engagement, Moderation, Innovation and Rigour.


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The estranged husband of missing Connecticut Mom Jennifer Dulos — Fotis Dulos — knows what the public thinks of him, and has a message for them: Wait until the facts come out.
"I know what I've done, I know what I haven't done," Dulos said in an exclusive interview with NBC 4 New York. "I have to stand and fight and hope the truth is going to come out."
It was Dulos' first interview since the disappearance of his estranged wife, Jennifer Dulos, more than a month ago. She went missing after dropping their five children off at school.
Fotis Dulos and his girlfriend Michelle Troconis — who he said he still loves and thinks she still loves him, though her attorneys have filed a no-contact order — have pleaded not guilty to evidence tampering and hindering prosecution charges in connection with the May 24 disappearance of the New Canaan mom. Police says Fotis Dulos and Troconis discarded items containing Jennifer Dulos' blood in Hartford.
NBC 4 New York on Twitter: http://4.nbcny.com/kAuuwUN
NBC 4 New York on Facebook: http://4.nbcny.com/mbeh714
NBC 4 New York on Instagram: http://4.nbcny.com/g5YlkcI
NBC 4 New York on Youtube: http://4.nbcny.com/iTUpy5e


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GAMES Evgen Makarenko took his fifth yellow card of the season against Racing Genk. He misses the home game of next weekend against Sporting Charleroi.
Makarenko took his yellow card slightly past the half hour when he touched Pozuelo's heels.
Source: © Internal source
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An Australian, Family-Owned, Local Manufacturing Jeweller.
Here at Lippitts our focus and passion is turning your dreams into reality with our beautifully and professionally made Custom Jewellery!Learn More
We do professional quality repairs, from broken chains to ring resizing and stone setting. All done on-site by our very own Master Jeweller. Bring your loved Jewellery in for a free check up today!Learn More
Our independent certified Gemologist has been an expert in her field since 1988. We offer a safe and easy way to have your precious pieces inspected and certified for insurance and peace of mind. Every valuation comes with a photo and detailed description of all materials used to create your piece.Learn More
We can remodel your old pieces to turn them into something incredible!Learn More
We can help you with your insurance claims, just come in and talk to one of our friendly staff.Learn More
We offer a Pearl rethreading service to give your pearls a brand new life. We can rethread graduating pearls double strands and all types of Pearl strands. Contact us today for a free quote.Learn More
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The Ford Crestline is an automobile which was produced by the Ford in the United States for models years 1952 to 1954.[1]
The Crestline was introduced as the top trim level of the 1952 Ford range, above the intermediate-level Customline and base level Mainline.[1] It was offered in Victoria, Sunliner and Ranch Wagon versions with 2-door hardtop, 2-door convertible and 4-door station wagon body styles respectively.[2] Crestlines were offered only with a 239 CID "L-head" V8 engine.[1]
The Crestline was updated with minor styling and trim changes for 1953.[1] It retained its position as the top trim level in the Ford range while body styles and engine availability also remained unchanged.[1]
For 1954 the Crestline was again updated with minor styling and trim changes.[1] Fordor Sedan and Skyliner versions were added, the latter being a 2-door hardtop with a tinted transparent panel in the front section of the roof.[3] New 223 CID straight-six and 239 CID overhead valve V8 engines were offered.[1]
The Crestline was replaced by the Ford Fairlane in the 1955 Ford range.[1]
1952 Ford Crestline Sunliner
1953 Ford Crestline Victoria
1954 Ford Crestline Fordor Sedan
1954 Ford Crestline Skyliner
Ford Motor Company, Station wagon, Ford Galaxie, Car classification, Ford Country Sedan
Ford Motor Company, Australia, V8 engine, Ford Fairlane (Americas), Brazil
Ford Motor Company, Ford Country Squire, Ford Fairlane (Americas), Ford Mainline, Ford Custom
Ford Motor Company, Ford Vedette, Henry Ford, Ford Taunus, Ford SAF
Ford Motor Company, Ford Fairlane (Americas), Ford Country Squire, Ford Country Sedan, Ford Custom


text: To read your mail, I had to 1. kill kmail (leading to two kbugthingy dialogs that requires 3 clicks each to get rid of, and to korganizer ALSO crashing, leading to two more dialogs) 2. restart akonadi 3. wait 4. start kmail again 5. wait while it did its lengthy mail checking. In my experience, Kmail is often in a defunct state, where new mail is not fetched, and as such not a reliable mail client. Apart from that, my experience is about in line with yours. Long waits, unreliability, lots of BSOD time. So YES, it is quite frustrating. Alternatives would be wellcome, as kmail is a hazzard. Kindly, Anders torsdag den 4. april 2019 13.46.42 CEST skrev Martin Steigerwald: > Hi. > > I did not write in a long time about own issues with KDEPIM/Akonadi and > instead tried to help others along here and there, but now I feel quite > frustrated… > > also due to own resistance to actually report a bug, I deal with a > regular crash of KMail¹ – regular as in several times a day. > > However, that is not the main issue. > > The main issue are two performance related issues (despite MariaDB > tuning and all that): > > 1) During mail retrieval KMail sometimes just stops displaying new mails > coming in. It GUI is responsive, but when I click on another folder or > so… I just get the waiting message. These stalls, that do not happen all > of the time, take up to a minute or even longer. > > 2) Filtering of new mail into folders takes very long. Very long means > up to 5 minutes or move of sustained activity of both Akonadi and > MariaDB for filtering 1000-2000 new mails. That is with me even making > sure to remove old mails from Akonadi's maildir entirely. Most folders > do not have more than 30000-40000 mails, some considerable less. A few > have 80000-100000 mails and I have the idea to remove mails out of them > as well. > > 3) Then I had one of the LRCONFLICTs displayed in KMail's status line > without even able to expand it to see what is is about. I solved it by > clearing Akonadi cache of incoming folder. > > At the same time due to introduction of Office 365 at work² I partly use > Evolution with EWS and I found the following: > > 1) Evolution did not crash *once* so far. > > 2) Evolution just works. For me so far, that is. > > 3) Evolution does not get stuck. > > 3) So far I do not see much of a performance issue. There are some short > stalls at time, but nothing even almost as unbearable as with KMail and > Akonadi. > > Granted the amount of mails in my work-around is considerably lower. And > while KMail does not crash several times a day with my work setup, it > still crashed once in a while. Also Akonadi gets stuck with IMAP or EWS > connection or whatever else. > > > Now, I know how much I defended KDEPIM / Akonadi, but… I also see the > amount of effort you, Daniel, and others put into fixing things up and > even changing Akonadi in some fundamental ways in order to make it work… > I truly appreciate that work… > > but I am also tired. > > Simply put: I am fed up with it. > > Yes, I see the recent improvements in Akonadiconsole to help others > report meaningful bugs and all that… > > but I do not like to be a database admin or a server administrator just > to read my mail and respond to them or write a bug report. > > KMail is still *just* a mail program. > > Akonadi does not have issues since yesterday. I'd say it had issues till > the beginning. I might have been lucky at times where it mostly worked > for me, but also I moved through a ton of issues and pain with KDEPIM > and Akonadi. > > I am sorry to write but I have found myself seriously considering to > switch away from KDEPIM, as much as I like KMail. > > The only other idea I had is to just switch from MariaDB to PostgreSQL. > It would mean a PostgreSQL upgrade once in a while, but it if works > better, I'd probably do that. Especially after I somewhere skimmed that > you, Daniel, wrote about a kind of locking issue with MariaDB/MySQL. And > also since you, Daniel, as the only one I am currently aware of tackling > deep into Akonadi, AFAIK use PostgreSQL as well. > > I am reluctant as akonadictl fsck reported a lot of issues the last time > I used it, including about items without RID. I may like to export those > into files before attempting a switch as Akonadi still cannot reply > those. And still I also do not get how a maildir resource could ever > fail to write out the mail into the maildir as long as the filesystem is > healthy. I am also reluctant due to having to reconfigure about 100 or > more filter rules. > > Or I might give it another change till the rewrite of the search > infrastructure as one of the last steps to improve Akonadi's > architecture. > > Or at least wait till 18.12 or 19.04 packages are available and test > again. > > > But as much as it saddens me I am quite close to just being done with > it… and take the huge step to migrate away from KDEPIM / Akonadi. > > How long has Akonadi been in development? Way more than 5 year, even a > decade probably? It ought to be stable. > > Yet, just by monitoring KDEPIM bugs mailing list I know it is far from > being stable. > > Yes, I know I have argued in favor for attempting to fix up Akonadi… and > maybe its really close now with only one of the major steps in the major > architectural overhaul missing – new search infrastructure. > > And yes, I'd like to be convinced to hold out a little bit longer, but > on the other hand I did so again, and again, and again… > > and it still does not work as stable and robust as I'd like it to. I > still put up with issues that a software that is being developed for > more than 5 years – correct me if my memory is wrong – simply should not > have anymore. > > So maybe, just maybe it is important to start admitting that Akonadi is > still not in the state it is supposed to be… and consider all options… > > > I end it now, its already long enough. I am preparing for a recreational > time out. I will most likely be offline or mostly offline from Friday to > Monday. > > I bet it might spur quite a discussion or so… all I ask of you is to > stay friendly in tone. I truly see that KDEPIM developers are working > hard, just AFAIK there are only a few who dare to dig into Akonadi. Dan > and well David recently. > > I hope that this "rant" while honest is still friendly in tone. I still > remember walking around angrily in this room, venting "such a piece of > crap software" at quite some times. In hind sight I do not mean it that > harshly. I see the good ideas behind Akonadi as well, but the 18.08 > implementation of it, feels like a major burden to me. 17.12 has been > better, as it did not have the stalls during receiving mails and KMail > did not crash several times a day. But it still used a lot of resources > and mail filtering was still slow. However it was a lot more bearable > than 18.08 appears to me. > > > [1] Bug 404052 - Crash during/after filtering inbox, probably related to > Qt WebEngine integration > https://bugs.kde.org/404052 > > [2] I do not agree with that move, but that is how it is currently… > > Thanks,


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What does the emblem mean?
Location, location, location.
Our store owner herself, Molly Carter, is a Placerville native. At 17 @mollyerindesigns left to see the "bigger, better" world outside this little town and found that after 10 years of exploring big cities there was still a lot to love about her hometown.
"Now I enjoy and really appreciate it. I think it's cool because there's so many young entrepreneurs staring new businesses and restaurants and Ben and I are proud to be a part of that."
(Molly's husband Ben owns the restaurant directly across the street @originalheydaycafe . And trust us, we're not just biased- it's way good! 😋 )
So when Molly was working with @studioplumb to create the company graphics and logo, they knew they had to incorporate her roots. 🤗
The logo is actually a map of downtown Placerville, Main Street where our shop is located. 📍
We love being in between Sacramento and Tahoe and welcome the residence and travelers alike to pop in to find something special for their home. 💕
Here is a little glimpse of our grand opening story on Good Day Sacramento!!
Follow us on Instagram…


text: UMHLOBO Wenene FM deejay Mthobeli 'KCI' August says he is not having sleepless nights over his latest suspension. KCI tells Move! that his suspension was the latest attempt "by some forces to destabilise me".Read more of this story in the 27 May 2015 Move! issue out in stores now.Subscribe now and get a 30% discount on SA's most-loved women's magazine, delivered digitally to your PC, tablet or any other mobile device for only R31 a month or R374.85 per annum!To subscribe, visit http://bit.ly/1MwNzRQ.


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Ship unloader protects environment
An Israeli port is taking measures to reduce its environmental impact with a new enclosed high capacity ship unloader that prevents dust and spillage.
Ashdod Port Company Ltd has signed a contract with Bruks Siwertell for the delivery of a toally enclosed Siwertell ST 490-M screw-type ship unloader which will be rail-mounted and used to discharge sulfur and pet coke at continuous rated capacities of 600t/h and 500t/h respectively from vessels up to 60 000 dwt at Ashdod Port.
"Ashdod Port Company chose Siwertell technology to secure its substantial and growing dry bulk cargo volumes for a number of reasons," explained Bertil Andersson, Siwertell sales manager. "Most significantly, our Siwertell unloaders are the only proven solution for safe, enclosed and continuous sulfur unloading. They also meet the port's strict environmental requirements, handling materials without dust or spillage."
Ashdod's bulk terminal operates 24 hours a day and the new ship unloader is destined to serve this facility. The Siwertell ship unloader has been ordered as part of the port's major expansion plans.
Safety first
Although a valuable and widely used commodity, sulfur is highly toxic, volatile and corrosive. For these reasons, it is now environmentally unacceptable for it to be spilled during unloading. However, its containment increases the likelihood of 'hot spots' creating the potential to explode and cause fires.
"We know how to deal with these dangers," noted Mr Andersson. "Our sulfur-handling ship unloaders have been supplied to the market for over 30 years.
"All these units are fitted with the Siwertell Sulfur Safety System (4S), which detects and extinguishes fires early, shutting down the system to stop their spread, and safely containing them before they can become a full-blown blaze.
"To contain explosions, steel casings are reinforced and explosion-venting valves are fitted along the conveyors to relieve pressure."
Delivery is scheduled for April 2021.
Amsterdam, 10 September 2019 – Today, Smart Freight Centre and the World Business Council for Sustai... Read more
SANY Boosting Business in Europe for Container Handling Equipment
SANY Europe have had a very busy 1st half of 2019. Several orders have been secured and machines hav... Read more
Port of Muuga strengthened with new ferry connection to Finlan
The Estonian terminal operator HHLA TK Estonia, a fully owned subsidiary of Hamburger Hafen und Logi... Read more
See JCB'S new electric-powered Teletruk at IMHX 2019
On its stand at IMHX 2019 JCB will showcase models from the multi-award winning Teletruk range of te... Read more
Best quarter ever for Port of Antwerp
The total freight volume handled by Port of Antwerp was up 0.7% during the first six months compared... Read more
Yara takes Siwertell ship unloader to the world's furthest reaches
Bruks Siwertell has completed the on-time installation and successful performance tests of a new 600... Read more


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Parallel Verses
New Living Translation
"Moses my servant is dead. Therefore, the time has come for you to lead these people, the Israelites, across the Jordan River into the land I am giving them.
King James Bible
Moses my servant is dead; now therefore arise, go over this Jordan, thou, and all this people, unto the land which I do give to them, even to the children of Israel.
Darby Bible Translation
Moses my servant is dead; and now, rise up, go over this Jordan, thou and all this people, into the land which I give unto them, to the children of Israel.
World English Bible
"Moses my servant is dead; now therefore arise, go over this Jordan, you, and all this people, to the land which I give to them, even to the children of Israel.
Young's Literal Translation
'Moses my servant is dead, and now, rise, pass over this Jordan, thou, and all this people, unto the land which I am giving to them, to the sons of Israel.
Joshua 1:2 Parallel
CommentaryWesley's Notes on the Bible
1:2 Now therefore arise - Let not the withering of the most useful hands be the weakening of ours. When God has work to do, he will either find or make instruments fit to carry it on. Moses the servant is dead; but God the master is not: he lives forever. This Jordan - Which is now near thee, which is the only obstacle in thy way to Canaan. Which I give - That is, am now about to give thee actual possession of it, as I formerly gave a right to it by promise.
Joshua 1:2 Parallel Commentaries
LibraryBrave Encouragements
'In the seventh month, in the one and twentieth day of the month, came the word of the Lord by the prophet Haggai, saying, 2. Speak now to Zerubbabel the son of Shealtiel, governor of Judah, and to Joshua the son of Josedech, the high priest, and to the residue of the people, saying, 3. Who is left among you that saw this house in her first glory? and how do ye see it now? is it not in your eyes in comparison of it as nothing? 4. Yet now be strong, O Zerubbabel, saith the Lord; and be strong, O Joshua, …
Alexander Maclaren—Expositions of Holy Scripture
Getting Ready to Enter Canaan
The Routing of Giant Doubt
Light through Darkness
Cross References
Numbers 12:7
But not with my servant Moses. Of all my house, he is the one I trust.
Deuteronomy 34:5
So Moses, the servant of the LORD, died there in the land of Moab, just as the LORD had said.
Joshua 1:1
After the death of Moses the LORD's servant, the LORD spoke to Joshua son of Nun, Moses' assistant. He said,
Joshua 1:11
"Go through the camp and tell the people to get their provisions ready. In three days you will cross the Jordan River and take possession of the land the LORD your God is giving you."
Job 1:8
Then the LORD asked Satan, "Have you noticed my servant Job? He is the finest man in all the earth. He is blameless--a man of complete integrity. He fears God and stays away from evil."
Jump to PreviousArise Children Cross Dead Israel Israelites Jordan Moses Ready River Servant
Jump to NextArise Children Cross Dead Israel Israelites Jordan Moses Ready River Servant
LinksJoshua 1:2 NIV
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Joshua 1:2 Bible Apps
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Joshua 1:2 German Bible
Joshua 1:2 Commentaries
Bible Hub


text: Is there a way to find out which gpu the game is running on at runtime? My game causes high GPU load (for an integrated GPU). If the user clicks the game, the default gpu is integrated one, I cannot change this easily but this makes the game run slower. At least, I want to warn the user when he/she uses the lower GPU.


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it isn't the same for them as it would be for us by Yorktone
Street Photo on UPSP
Urban Picnic Street Photography | Street Photographer Community
#upsp #streetphotography #streetphoto #streetphotographer
blackandwhite • orwell • street • yorktone
Yorktone has published 4 street photos in UPSP.
Urban Picnic Street Photography
A place to find inspiration, upload your best photographic work and develop ideas based on the street theme. Urban Picnic strives to showcase the best street photography and feature the best contemporary street photographers.


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Skin Confident
Skin Confident offers an accessible, friendly and expert skin camouflage service in a central London location. Skin Confident can help you reduce the appearance of difficult skin conditions to help you feel your most confident.
Do you, or someone you know, have a similar story to tell? Get in touch today to earn £££ and raise awareness.


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We drive order volume & never take any commissions or percentage off your orders!
Finally. Commission-Free Orders. Time for a toast!
Access our hungry businesses & corporate client network.
Gain immediate access to feed our business clientele, many of whom exclusively place their daily staff lunching or catering orders through our platform.
Dishes has grown our corporate food sales by over 257% in a short time. - Tom McSheen
Fast order notification so you'll never miss another customer.
Get orders sent to you in real-time by e-mail or mobile notification, and allow staff to easily manage them directly in your Merchant Portal. You're in total control!
Dishes is so easy to use. We're notified of orders and can easily accept and schedule them in our dashboard. - Deborah Cox
Fast and easy restaurant payouts.
They're your orders, so you expect to paid...quickly. We get it! That's why we pride ourselves in having the fastest restaurant/caterer payouts in the industry.
I was hesitant at first, but now I'm proud to be on Dishes as they are honest, fair, and fast. - Jon Barring
The Days of Paying Commissions or Percentages Are Over.
Powerful dashboard to customize menus & manage orders.
Dishes offer restaurants and caterers a powerful, yet easy to use dashboard to fully customize your menus, manage customers & fulfill orders.
Powering food orders for companies in multiple markets ...
Our growing nationwide network of businesses are driving food orders at historic levels.
...and connecting them our restaurant and catering
partners to feed their staff.
Karen Ann Mortensen
The Olive Bistro
We needed a way to preserve our margins.
"As a small restaurant establishment we needed a way to propel our sales and found Dishes to be just what we needed to boost our brand in our local market. It turned out to be the fastest way to our success."
Take your online food orders & catering to the next level.
Expand your business lunching and corporate catering sales immediately with our captive network.
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This agreement set forth ("Terms") are applicable to the service relationship between Dishes Inc., (collectively, "Dishes") and the Restaurant, Caterer, or Food Retailer ("Merchant") which is present on the Dishes' online web marketplace portal and any accompanying mobile applications ("Platform"). These Terms and the Services set forth will be referred to as the "Agreement." The Agreement is entered into as of the date of activation of the Merchant onto our website and any mobile applications ("Effective Date").
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A Trip To This Little Known Ancient Ruin In Virginia Is Truly One In A Million
The term "ancient" may be relative, yet what remains at the old Midlothian Mines can only be described as ruins. Tucked away in the woods just outside of Richmond, you'll find a fascinating park that will take you deep into Virginia's mining history. It all began in the 1730s, when Virginia began the first commercial coal operations in the United States at this very location. Coal from this source was used to make ammunition for the Revolutionary War and efforts of the Civil War. Walking among this ruins, you won't help but feel the immensity of this extensive, and at times troubling, history.
Midlothian Mines Park is located at 13301 N. Woolridge Rd., Midlothian, VA 23114. Curious to see more relics around Virginia? Be sure to check out These 6 Trails That Lead You To Extraordinary Ancient Ruins In Virginia.