text:
7+ technical memorandum format
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"Euan has piped at various dinner dance receptions that I have organised for large prestigious financial companies. He was diligent in:
• ensuring that he understood the nature of the event
• suggesting suitable music
• being proactive in ensuring that all guests had the ability to hear and see him
• ensuring that he was early to the event in order to finalise arrangements
There is no questioning Euan's ability as a Piper. His piping pedigree speaks for itself.
I would highly recommend Euan for any type of event."
Maree Notman
"A tremendous musical talent and true professional in every sense of the word.
Euan has the experience and personal qualities to make any event very special."
Jim Stack
"I have been involved in functions with Euan on many occasions and his approach to everything is always meticulous and professional."
Scott Hannah
"The consummate professional."
Colin MacLellan
"Thank you for making our Wedding day so special"
Jennifer Underwood March 2017
Many thanks for the wonderful music at our wedding. What fantastic day and having you there as our piper was the icing on the cake.
Suzannah and Michael-May 2017
Hey Euan! Thank you so much. It was bloody brilliant. The feedback has been incredible. I'm just waiting on the photos being sent to me and I'll get one over to you.
Thanks again! Until next time 😁
Nicola (Shields-Valentus) June 2017
It was lovely to meet Euan last week. We have received very good feedback, the client was delighted with his dress and music choices.
Morag at The Royal Botanics Gardens July 2017
Many thanks for hosting the dinner at the Waldorf Astoria Euan. Another magical evening.
Capt. John MacLellan Trust. August 2017
Thank you so much for playing at my birthday party. It brought a tear to my eye. Mary
October 2017
It is with our ever grateful thanks for your fantastic piping and respect at our dear dad's funeral yesterday, so many people commented how wonderful you were. I'm so sorry I never got the chance to thank you in person.
With Thanks and Kindest Regards,
Suzanne Lampard. November 2017
Thank you again for piping at our wedding. It was excellent and on such a cold winters day, well received by everybody, myself and most importantly the bride.
Euan McCorquodale
Thank you so much for today. My dad would have been so pleased. I am sorry I did not get a chance to thank you in person at the cemetery but I am sure you understand. You added to a great send off for him.
Julie Duff
Thank you for being our wedding piper and for being part of our day. We've really enjoyed the journey with you and are very grateful to have you on board. Look for your new bagpipe umbrella in the post :) with love John and Caitlin.
Thanks for playing at the charity gig Euan. Our first time and it will be even bigger and better next year. Hope to see you then. Best wishes Seamus
It was not the best day but thank you so much for giving your time for a great cause, the 2018 Kilt Walk. The It's Good to Give Charity Team 2018
Thanks so much for being part of the Innes and Gunn day. The Flower of Scotland in the house was overwhelming. Pity about the result :( Kerrie and Kevin Crabbe Feb 2019.
We wanted to give people a 'Taste of Scotland' and that's exactly what you delivered. The service was impeccable and extremely professional. The piper and haggis address was fabulous.Colin BITUG (British Isles Tandem User Group) May 2019
Thank you for being a part of our special day. We are not from Scotland but fell in love with it and Dundas Castle. Gary Bendell and Lyn Brymer. May 2019
Hi, My wife and I would like to thank you for making our wedding day even more special than we could have hoped for, even though you absolutely upstaged Liz and l. Everyone at the reception (staff also) thought you were great. If l ever do it again l will give you a call. Best regards, Liz and Allan Clarke. June 2019


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A Study Of Avelumab In Combination With Axitinib In Advanced Renal Cell Cancer (JAVELIN Renal 100)
|The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
|ClinicalTrials.gov Identifier: NCT02493751
Recruitment Status : Active, not recruiting
First Posted : July 9, 2015
Results First Posted : June 21, 2019
Last Update Posted : June 21, 2019
- Study Details
- Tabular View
- Study Results
- Disclaimer
- How to Read a Study Record
|Condition or disease
|Renal Cell Cancer
|Drug: Avelumab (MSB0010718C) Drug: Axitinib (AG-013736)
|Phase 1
|Study Type :
|Interventional (Clinical Trial)
|Actual Enrollment :
|55 participants
|None (Open Label)
|Primary Purpose:
|Official Title:
|Actual Study Start Date :
|October 15, 2015
|Actual Primary Completion Date :
|April 3, 2018
|Estimated Study Completion Date :
|January 22, 2020
Experimental: Dose finding phase and dose expansion phase.
To test the maximum tolerated dose of avelumab (MSB0010718C) in combination with axitinib (AG-013736)
Drug: Avelumab (MSB0010718C)
Avelumab with two dose levels: 10 mg/kg IV and 5 mg/kg IV every two weeks to find the maximum tolerated dose in combination with axitinib and continue treatment in a dose expansion.
Drug: Axitinib (AG-013736)
Axitinib with two dose levels: 5 mg and 3 mg oral BID to find the maximum tolerated dose in combination with avelumab and continue treatment in a dose expansion.
- Number of Participants With Dose Limiting Toxicities (DLTs) [ Time Frame: DLT observation period (from the beginning of Cycle 1 up to the end of Cycle 2 [28 days]) ]DLT: greater than or equal to (>=) Grade 3 hematologic/non-hematologic toxicity, Grade 3-4 liver-related laboratory test elevation (alanine aminotransferase, aspartate aminotransferase) with Grade 2 elevation of total bilirubin, non-hematologic Grade 3 laboratory abnormality (required medical intervention to treat participant/led to hospitalization), inability to complete >=75% of first 2 cycles doses of axitinib (from Cycle 1 Day 1 after completion of lead-in period) or 2 infusions of avelumab within DLT observation period due to investigational product related toxicity.
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies.
|Ages Eligible for Study:
|18 Years and older (Adult, Older Adult)
|Sexes Eligible for Study:
|Accepts Healthy Volunteers:
Inclusion Criteria:
- Histologically or cytologically confirmed advanced RCC with clear cell component
- Primary tumor resected
- Availability of a recent formalin-fixed, paraffin-embedded (FFPE) tumor tissue block from a de novo tumor biopsy during screening (biopsied tumor lesion should not be a RECIST target lesion). Alternatively, a recently obtained archival FFPE tumor tissue block (not cut slides) from a primary or metastatic tumor resection or biopsy can be provided if the following criteria are met: 1) the biopsy or resection was performed within 1 year of enrollment AND 2) the patient has not received any intervening systemic anti-cancer treatment from the time the tissue was obtained and enrollment onto the current study. If an FFPE tissue block cannot be provided as per documented regulations,, 15 unstained slides (10 minimum) will be acceptable.
- Availability of an archival FFPE tumor tissue block from primary diagnosis specimen (if available and not provided per above). If an FFPE tissue block cannot be provided, 15 unstained slides (10 minimum) will be acceptable
- At least one measureable lesion as defined by RECIST version 1.1 that has not been previously irradiated.
- Age ≥18 years (≥ 20 years in Japan).
- Eastern Cooperative Oncology Group (ECOG) performance status 0 or 1
- Adequate bone marrow function, renal and liver functions
Exclusion Criteria:
- Prior systemic therapy directed at advanced RCC.
- Prior adjuvant or neoadjuvant therapy for RCC if disease progression or relapse has occurred during or within 12 months after the last dose of treatment
- Prior immunotherapy with IL-2, IFN-α, or anti PD 1, anti PD L1, anti PD L2, anti CD137, or anti cytotoxic T lymphocyte associated antigen 4 (CTLA 4) antibody (including ipilimumab), or any other antibody or drug specifically targeting T cell co stimulation or immune checkpoint pathways
- Prior therapy with axitinib as well as any prior therapies with other VEGF pathway inhibitors.
- Known severe hypersensitivity reactions to monoclonal antibodies (Grade ≥3), any history of anaphylaxis.
- Any of the following in the previous 6 months: myocardial infarction, severe/unstable angina, coronary/peripheral artery bypass graft, symptomatic congestive heart failure, cerebrovascular accident, transient ischemic attack, deep vein thrombosis or symptomatic pulmonary embolism.
- Vaccination within 4 weeks of the first dose of avelumab and while on trial is prohibited except for administration of inactivated vaccines (for example, inactivated influenza vaccines).
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT02493751
|United States, Arizona
|Oncology Research Associates, PLLC d/b/a Pinnacle Oncology Hematology
|Scottsdale, Arizona, United States, 85258
|United States, District of Columbia
|Georgetown University Medical Center Department of Pharmacy, Research
|Washington, District of Columbia, United States, 20007
|Georgetown University Medical Center
|Washington, District of Columbia, United States, 20007
|United States, Massachusetts
|Brigham & Women's Hospital
|Boston, Massachusetts, United States, 02115
|Beth Israel Deaconess Medical Center
|Boston, Massachusetts, United States, 02215
|Dana-Farber Cancer Institute
|Boston, Massachusetts, United States, 02215
|United States, New York
|Laura & Isaac Perlmutter Cancer Center At NYU Langone
|New York, New York, United States, 10016
|NYU Langone Medical Center
|New York, New York, United States, 10016
|United States, Ohio
|Cleveland Clinic Taussig Cancer Center
|Cleveland, Ohio, United States, 44106
|Cleveland Clinic
|Cleveland, Ohio, United States, 44195
|United States, Tennessee
|Henry Joyce Cancer Clinic
|Nashville, Tennessee, United States, 37232-5310
|United States, Utah
|University of Utah, Huntsman Cancer Hospital
|Salt Lake City, Utah, United States, 84112
|University of Utah, Huntsman Cancer Institute
|Salt Lake City, Utah, United States, 84112
|Niigata University Medical & Dental Hospital
|Chuo-ku, Niigata, Niigata, Japan, 951-8520
|Kindai University Hospital
|Osakasayama, Osaka, Japan, 589-8511
|Keio University Hospital
|Shinjuku-ku, Tokyo, Japan, 160-8582
|United Kingdom
|Mount Vernon Cancer Center, East and North Herts. NHS Trust
|London, Middlesex, United Kingdom, HA6 2RN
|St Helier Hospital
|Carshalton, Surrey, United Kingdom, SM5 1AA
|St. Bartholomew's Hospital
|London, United Kingdom, EC1A 7BE
|The Royal Marsden NHS Foundation Trust
|London, United Kingdom, SW3 6JJ
|The Christie NHS Foundation Trust
|Manchester, United Kingdom, M20 4BX
|The Royal Marsden NHS Foundation Trust
|Sutton, United Kingdom, SM2 5PT
|Study Director:
|Pfizer CT.gov Call Center
Documents provided by Pfizer:
Additional Information:
Publications automatically indexed to this study by ClinicalTrials.gov Identifier (NCT Number):
|Responsible Party:
|ClinicalTrials.gov Identifier:
|NCT02493751 History of Changes
|Other Study ID Numbers:
2015-001137-25 ( EudraCT Number )
Javelin Renal 100 ( Other Identifier: Alias Study Number )
|First Posted:
|July 9, 2015 Key Record Dates
|Results First Posted:
|June 21, 2019
|Last Update Posted:
|June 21, 2019
|Last Verified:
|March 2019
|Individual Participant Data (IPD) Sharing Statement:
|Plan to Share IPD:
|Plan Description:
|Pfizer will provide access to individual de-identified participant data and related study documents (e.g. protocol, Statistical Analysis Plan (SAP), Clinical Study Report (CSR)) upon request from qualified researchers, and subject to certain criteria, conditions, and exceptions. Further details on Pfizer's data sharing criteria and process for requesting access can be found at: https://www.pfizer.com/science/clinical_trials/trial_data_and_results/data_requests.
Cancer, renal cell cancer, kidney disease, kidney neoplasms, axitinib
Carcinoma, Renal Cell
Neoplasms, Glandular and Epithelial
Neoplasms by Histologic Type
Kidney Neoplasms
Urologic Neoplasms
Urogenital Neoplasms
Neoplasms by Site
Kidney Diseases
Urologic Diseases
Antibodies, Monoclonal
Immunologic Factors
Physiological Effects of Drugs
Antineoplastic Agents
Protein Kinase Inhibitors
Enzyme Inhibitors
Molecular Mechanisms of Pharmacological Action


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Climb aboard dozens of boats hosted by Lake Wallenpaupack's leading marinas and powersport centers including Lighthouse Harbor Marina, New Wave in Recreation, Captain Joe's Sales & Service, Inc., 1st Klas Marina, The Boat Shop, Rusty Palmer, Inc., Seeley's Marina and others. See the latest in watercraft, pleasure, pontoon, ski and wakeboard boats. Event topped off with various exhibitors and food stands including I-84 Country Store's World Famous BBQ, free face painting by Face the Art Face Painting.
Back to All Events
Earlier Event: August 25Kayak Demos and Standup Paddleboards
Later Event: August 25Train to Wally Lake Fest ~ Stourbridge Train Rides


text:
Personal Training, Specialty Training and Nutrition Services available for adult & youth. For Appointments call 303-483-7089 at Goodson and Sheridan, 303-730-4610 at Buck and 303-708-3514 at Lone Tree. See listing of Personal Trainers at recreation centers:
Goodson Personal Trainers
Buck Personal Trainers
Lone Tree Personal Trainers
Individual 60-minute session which includes orientation and set-up on a variety of cardiovascular and weight machines.
Contact: firstname.lastname@example.com
South Suburban Parks and Recreation6631 S University BlvdCentennial, CO 80121
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One of the questions I get asked the most is about my hair. To tell you the truth, I don't have some extensive haircare routine but I do try and keep it under control with a few products from Percy & Reed. You may have noticed that I travel quite a lot, whether it's a UK Staycation or abroad on a longer holiday, I like having my hair tamed. I've recently using the Percy & Reed Wanderlust Travel Set*, it's perfect as it has everything I need for a trip away. This set came away on my Birthday trip to Chester & Liverpool a couple of weeks ago.
The Wanderlust Travel Set comes with a Wonder Care Shampoo and Conditioner, Wonder Balm, Session Hold Hair Spray and a Hydrating Body Wash. I love that it comes with a Body Wash as they set literally has everything you need whilst on your travels not limited to haircare! One of the main things that I love about Percy & Reed products is the very distinctive scent that leaves you smelling like you are fresh from the salon. The Body Wash actually has the same scent which I absolutely love. It's limited edition to the Wanderlust Travel Set but I believe you can currently get it from their website here.
The Wonder Care Shampoo and Conditioner are both in my haircare routine whilst I'm at home and travelling. With the Conditioner, I tend to use quite a generous amount and leave it in my hair for five minutes before rinsing. You can really tell a difference if you massage it on the ends too. It leaves my hair so soft and silky when dry.
The set also contains their Wonder Balm and a Session Hold Hair Spray which is great if you're styling your hair. I'd say the one thing missing from the set is a heat defence spray for when you're using a hair dryer, curling tongs or straighteners. I always use heat defence spray just so it's protected from the heat. On average, I use heat on my hair only once a week. It tends to use curling tongs with the hair spray which is great at keeping it styled and held together.
I don't take it away on every trip but if I have room in my luggage I'll bring along the Percy & Reed Texture Spray. I have the full sized version of this and it's great for giving your hair a little something about it when you've got waves running through.
The Percy & Reed Wanderlust set is a great addition to my travels to keep my locks under control. The set is actually worth £32.50 but retails at £24 and would last you a couple of trips. As I've been away a lot recently, I've managed to get through the Shampoo and Conditioner quite quickly so I've just been topping the miniatures up with my full size ones. Perfect size for travelling with!
*This post contains PR Samples
it sounds divine and i really love the drawings on the packaging!
xx from italy
Cate ღ 35mm in Style
Amazing photography here!
Anika | anikamay.co.uk
I have used a bit of Percy & Reed before and found it really good – I love they do sets, I might have to put them on my christmas list so I can try some other products from them!
Ooo these sets look fab. Not heard of this brand before, but I may give them a go x
I love the look of the percy and reed products and the size of them looks great for travelling, I just wish they did products that would work in my curly hair.
Such pretty bottles, I wouldn't want to use it LOL
I havent heard of this brand before but I love the look of them, the packaging is lovely! Travel sized products are always great!
I haven't heard of this brand as well but looks like it's a good buy.
I absolutely love Percy & Reed products. They always leave my hair looking and feeling fab 🙂
Louise x
The packaging is really nice and the product photography is good! 🙂 x
These products look great and the packaging is fab. I love trying new hair care products so I'll check these out.
I love the look of these, I've never used them before but the packaging looks wonderful.
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MILWAUKEE -- Alverno College swept visiting Edgewood College in the Inferno's final home series of the season Friday evening by scores of 3-1 and 7-5.
Kristin Holub was also honored between games as the Alverno squad celebrated her four-year career on Senior Day at Alverno Field.
The Inferno (12-24, 5-15 Northern Athletics Collegiate Conference) opened up the scoring in game one in the bottom of the third inning as Kaitlynn Johnson drew a bases-loaded walk to plate Karissa Minster who lead off with an infield single.
Samantha Chapnick followed with a hit through the right side to score Bailey Jedrzejewski and give the hosts a 2-0 lead.
Mackenzie Mathies led off the fourth with a single down the third-base line and Jedrzejewski reached to put runners at the corners. Jedrzejewski was tagged out attempting to steal second but Mathies took home on the play for the three-run lead.
Grace Delleman had a pinch-hit double in the top of the six to score the Eagles (4-32, 1-19 NACC) only run of the contest.
Mathies recorded her 14th steal of the season in the fourth to break the single-season school record.
Ashlie Rossi (6-13) scattered nine hits and struck out four in the complete-game victory while Shannon Whitmus (4-25) allowed just five hits in the loss.
Edgewood struck first in game two as Jordan Anderson placed a single up the middle to score a pair of runners after the Eagles loaded the bases on three consecutive infield hits to begin the game.
An Inferno error and passed ball allowed another Edgewood run in the top of the third but Alverno got one back in the bottom half of the inning as Chloe Fleming scored on a wild pitch and took advantage of an Eagle error in the fourth to make it 3-2.
Delleman homered to make it 4-2 in the fifth before the Inferno offense scored five runs on four hits and an error in the bottom of the inning for a 7-4 advantage.
Carina Jimenez singled up the middle to score Olivia Schneider, who walked, and Dani Hood, who had the Inferno's first hit of the game. Chapnick scored two more with an RBI-single to right field and Holub squeezed home Mathies in the senior's final home at-bat.
Schneider (6-11) went the distance in the circle for the win with seven strikeouts while Whitmus had six Ks in her second complete-game loss of the evening.
Jimenez accounted for two of the Inferno's six hits in the contest to lead the offense.
Alverno looks to wrap up the season tomorrow at Rockford University. The doubleheader is at 12 p.m. in Rockford, Illinois.


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The head of the Ministry of Emergencies attended the scene of the incident.
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There are total 8 letters in Wooingly, Starting with W and ending with Y.
Wooingly is a scrabble word? Yes (15 Points) Wooingly has worth 15 Scrabble points.
Definition of the word Wooingly, Meaning of Wooingly word :
adv. - In a wooing manner, enticingly, with persuasiveness.
An Anagram is collection of word or phrase made out by rearranging the letters of the word. All Anagram words must be valid and actual words.
Browse more words to see how anagram are made out of given word.
In Wooingly W is 23rd, O is 15th, I is 9th, N is 14th, G is 7th, L is 12th, Y is 25th letters in Alphabet Series.
Copyright © Word Creation 2017. All Rights Reserved


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Jeffrey E. Stambaugh (John Martinez (G. T. Lumpkin (Niyati Kataria (
Additional contact information Jeffrey E. Stambaugh: Midwestern State University
John Martinez: Midwestern State University
G. T. Lumpkin: University of Oklahoma
Niyati Kataria: Midwestern State University
International Entrepreneurship and Management Journal, 2017, vol. 13, issue 3, No 2, 717-737
Abstract The Entrepreneurial Orientation (EO) research stream is quite popular in investigating how companies act entrepreneurially and how EO relates to issues such as financial performance, innovation, and founder satisfaction. Part of EO's popularity may be that it is measured using simple, widely-accepted items. Yet the idea of how to best measure EO has become a recent topic of debate. Part of that debate is that the items measure dispositions as much as behaviors and are self-reported, which means they are somewhat subjective. This paper investigates the relationship between subjectively-measured EO and actual entrepreneurial behavior as measured through objective data. To do so, the paper examines the relationship between EO dimensions and realized risk-taking behavior. Using a sample of 156 community banks headquartered in the southwestern United States, the paper uses banks' risk-weighted asset ratio, which captures the riskiness of the bank's portfolio, as a measure of sustained entrepreneurial behavior. The analysis finds that subjectively-measured EO risk-taking is strongly related to objectively-measured realized bank risk-taking. There was not a significant direct relationship with the other EO dimensions, though there was some evidence of a moderated relationship. The paper lends some credibility to current EO measures and suggests how additional research is needed to improve upon EO's measurement.
Keywords: Entrepreneurial orientation; Risk-taking; Measurement; Banking (search for similar items in EconPapers)
Date: 2017
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Honor Level should matter!
I hear often that people quit the game because of the toxic community and thats bad, because the people who leave are often friendly and the ones who stay become toxic themselves. I think this could be fixed if they worked a bit on the Honor Level and made it mroe than just a cosmetic. I would love to see something like a ''Karma System'' which works like that: 1. Every player who created an Account starts out with 0 Karma. 2. Honors makes your Karma go up and Reports lower it. 3. Give the option to honor more than one player and even the enemies. (Thats just fair if there were more than 1 player you enjoyed playing with) 4. Different kinds of honors and reports have different value. 5. Players can choose more than 1 kinds of honor for a single player. (That way you will not only be rewarded for f.e. being friendly or doing well, but for both if the player thinks you deserve it) 6. If a player has low Karma his reports count less. (Toxic people love to report for no reason) 7. Your Karma only changes when youve been honored or reported in a Ranked Game. (Because Normals are a place where people test stuff and play for fun and they shouldnt get punished for performing badly because of it) 8. If you queue for a game you get matched with players close to your Karma (Only for Ranked). Please comment if you think there should be something else added or removed from what I said. (Sorry for my bad english <3)
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Understanding Phobias in Dogs: How to Get Your Dog to Stay Calm During a Fireworks Show
The Fourth of July is full of fun, activities and of course, fireworks. If you have problems with your dog during fireworks shows, there are several things you can do to help him or her.
"Why does my dog freak out during the Fourth of July?"
Dogs have no concept of fireworks. They don't understand what they're seeing, they don't understand that they are safe and they certainly don't hear that kind of loud boom often. Add all of this to a dog's sensitive hearing and you can see how a dog might feel afraid. To them, a firework going off is like one of us hearing gunfire from an automatic weapon going off near our homes (assuming that we don't live on a gun range, of course). They feel threatened and afraid for their lives.
What can I do to help my dog see that fireworks are harmless?
- Try to figure out what it is that scares your dog about fireworks. The noise, the lights, the reactions of his owner, etc. can all be culprit.
- If possible, start desensitizing earlier than the actual fireworks event. Play realistic sounds (there are lots of free fireworks sounds on youtube). Start softly and give your dog lots of treats. Only increase the volume if your dog seems capable of dealing with it.
- Don't react, jump or freak out when you hear the fireworks. Just act like it's no big deal. Your dog will be looking to you for guidance.
- Don't ignore your pet when he needs comfort. Sit on the floor with him and encourage him to come over to you. Reward him for walking around and being brave.
- Give your dog a treat every time a firework booms. Do this consistently and over time you'll see results.
If you have a young puppy that has never experienced fireworks...
- Don't leave the puppy alone in the house or in a crate. Keep the puppy with you while the fireworks start and begin preventative measures. How you handle your puppy's first experience with fireworks will effect how she views them the rest of her life.
- Play with your puppy, give your puppy lots of praise and distract her with a new bone or toy. Give your puppy a special treat every time a firework booms. She will quickly associate the fireworks with the treats.
- Do not force your puppy to go outside or to go closer to the fireworks if she's upset. Only do so in baby steps and if there is any sign of fear, go back inside immediately. If you push your puppy you could actually create a phobia.
- Do not get upset yourself. Stay calm. Don't shout and try not to get stressed out. You may be spending more time with your puppy than with your family, but handling it right can mean a problem free 4th of July for 10+ years to come.
- Do not allow other people to crowd your puppy, pet her roughly or allow her to have a bad experience while there are fireworks going off. Be weary and protective. Keep her away from commotion, noise and stress. Pair the noise of the fireworks with good things instead.
If you have an adult dog that is already weary of fireworks...
- If your dog has an extreme phobia, consider consulting with a qualified animal behaviorist.
- There is no *magical* solution you can buy to make your pet okay. If any thing is being advertised as such, don't buy it.
- Start slow. Play long, realistic video clips in the background on very low volume for several days before the show. While this is happening, give your dog treats. Turn up the volume if he can handle it, continuing to give your dog a treat every time he hears a firework.
On the Fourth of July
- Prevention:
- Take your dog out to potty before the fireworks begin and don't force him to go out side while they're in full swing. Never yell at your dog while he's afraid- it will only make the phobia worse. When he sees you freaking out he will think you are angry about the fireworks.
- Tire your dog out earlier in the day so that he has less energy to draw from when he's afraid.
- Keep your dog inside. Fearful dogs can slip out of their collars or pull away from their owners and be gone for days.
- Don't leave your dog alone if he is afraid. He will find much more comfort with you there. Being there and acting as though the fireworks are no big deal can go a long way toward making your dog less anxious.
During the Show:
- Distract your dog with a kong filled with high value treats, a new bone, or a new toy while fireworks are starting. Try to delay him noticing they have begun.
- Give your dog his favorite treats while the fireworks go off for as long as he allows it.
If he gets to a point where he no longer accepts the treats, this means he is severely anxious. Don't be frustrated with your dog. It does not mean that the treats aren't working. It means that he has reached his threshold and the fireworks have gotten too loud, bright, etc for him to handle before he is ready.
At this point you will need to play damage control to stop the overwhelming stimulus of the fireworks from making his phobia worse.
Damage Control
- Watch your dog when he begins to get severely anxious and stops taking treats. When does he seem most afraid? Does he shiver during the loud booms? Is he looking out the window to see the lights?
- Take away the stimuli that bother him by closing the window shades, turning on a fan to drown out the noise, turning on the television, etc. Do this in increasing increments. Set the fan to low at first and see if that helps, then go to a higher setting if it doesn't and so on.
- When your dog starts to calm down, offer him a treat. If he takes it, this means he is okay again. If he still will not take a treat, continue reducing the noise of the fireworks outside, wait a little while and try again.
How can I tell that my dog is afraid?
Here is a video of a dog with a mild-moderate phobia of fireworks. Notice the signs of fear: barking, pacing, whining, nervous tail wagging, panting, a large-eyed stare, trembling.
Dog Mild Phobia
What not to do: Do not antagonize your dog!
This next video is an example of someone that has antagonized their dog with fireworks, creating both an unsafe situation for the dog and a severe phobia.
It is difficult to believe that anyone would intentionally encourage their dog to be afraid when so many people want their dogs to enjoy fireworks with them and act normally. I am showing you this video to help you understand both what not to do, and to show that fear can be learned (and thankfully unlearned)
Notice the way that Brock responds negatively to just the word "fireworks." He cannot speak English and the only way he could have learned this association is through his owner. There's no way for him to know what that word means unless his owner thought his phobia was funny and actively encouraged it by giving it a name/association.


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GALWAY, Ireland - Thousands of people took to the streets in Ireland on Saturday in a politically charged memorial for an Indian woman allegedly refused the termination of her pregnancy because it was against the law.
Savita Halappanavar, a 31-year-old dentist originally from India, died in University Hospital Galway days after she miscarried. Her family say she asked for an abortion several times because she was in pain.
On Saturday more than 10,000 people attended a march in the Irish capital Dublin, police said, where a minute's silence was observed before pro-choice activists made speeches calling for legislative change.
In Galway on Ireland's west coast, where the Halappanavars lived and where her husband Praveen worked as an engineer, hundreds of people carrying candles took to the city's Eyre Square on a bitterly cold evening.
"I came here out of anger, sadness and disappointment. My own mother died in similar circumstances 50 years ago," Margaret Geraghty said, guarding the flame on her candle from the cold wind.
"This whole week has been a memory of that. I just can't believe this can still happen in today's world. I'm just glad Praveen had the bravery to tell the world about this."
The crowd stood in silence, many with heads bowed. As people left, they placed their candles on the ground underneath a poster of Savita emblazoned with the words: "Never again".
Irish authorities have launched an investigation into her death, and on Saturday Ireland's police said they were "assisting the coroner" in relation to the incident.
Abortion is illegal in predominantly Roman Catholic Ireland, except when it is necessary to save the life of the mother.
But that right exists only because of a 1992 Supreme Court ruling. Successive Irish governments have failed to introduce legislation to reflect this, leading to calls for action.
Savita Halappanavar was 17 weeks pregnant when she was admitted to hospital in early October with back pains. She died of septicaemia, or blood poisoning, on October 28.
Her husband has said doctors refused to give her an abortion despite her pleas because there was a foetal heartbeat and because Ireland was a "Catholic country".
In India, opposition protesters held a demonstration outside the Irish embassy on Friday over her death, and accused Irish authorities of committing "medical murder".
Foreign ministry spokesman Syed Akbaruddin said India's ambassador to Ireland would meet Irish authorities to seek assurances of a "transparent" probe.


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Whale Watching
Scroll to Continue
Whale Watching in Hawaii
Adult males range from 40 to 52 feet and can weigh up to 45 tons. Despite their size, humpback whales are graceful acrobats. Keep your eye on the ocean and you might see one breach, propelling up to 40 percent of its body out of the water and landing on its side with a spectacular splash.
Whales have great cultural significance for Native Hawaiians. They play a large role in Hawaiian legend—including one creation story—and appear in ancient petroglyphs on several islands. The return of the kohola (humpback whale) is considered more of a homecoming than a visit. Humpback whales are born in Hawaiian waters, making them kamaaina (native born). Some Native Hawaiians also believe the whales are aumakua (family guardians), so these gentle giants are treated with great respect.
Cultural Significance of Whales in Hawaii
Although humpback whales can be seen from all of the Hawaiian Islands, the shallow Auau Channel between Maui, Molokai and Lanai is one of the best whale-watching destinations in the world.
What's the Best Way to See Whales?
You may also spot kohola from the southern shores of Oahu, especially at Makapuu Lighthouse and along the seaside overlooks near Leahi (Diamond Head).
Kauai offers a range of whale-viewing opportunities, including Poipu Beach on the South Shore, Kilauea Lighthouse on the North Shore and Kapaa Overlook on the island's Coconut Coast.
On the island of Hawaii, whales are often seen along the shores of the Kohala Coast, as well as Hilo Bay on the east side of the island. The Puukohola Heiau National Historic Site is another great viewing spot, with its sweeping, elevated views near Kawaihae Harbor. In fact, Puukohola literally means "hill of the whale" in Hawaiian.
Boat tours may be your best option for viewing whales up close. Hawaii has dozens of tour operators, including a few that lead kayak excursions—a thrilling way to experience these majestic mammals.
In respect for the kohola and the safety of sightseers, all watercraft must stay a minimum of 100 yards from the whales, but you'll be surprised how close you feel when a 45-ton behemoth lunges out of the sea. If a boat tour is not for you, the whales' impressive acrobatic displays are often visible from miles away. If you're on land, keep a pair of binoculars handy because you never know when you'll see a humpback's spout (which can be 10–20 feet tall).
Whale Watching in Hawaii
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Now, it's not uncommon for attorneys to hire a local part-time bookkeeper to help reconcile bank statements once a month, but Kahuna Accounting has clients all over the United States yet its main office in Illinois. How do they do it? Cloud accounting software called Xero.
"As soon as we found Xero our accounting team fell in love with it," said Deming. Xero is cloud accounting software that works especially well for attorneys, since it integrates fairly seamlessly with third-party software like the popular case management software platform, Clio. Deming said, "Working well with Clio has led a lot of lawyers to Xero. We like it because it makes things faster. The business owners have said they can't believe how fast it is. We haven't looked back since we started using it."
Related: Clio Case Management Software Review
Most of the clients Kahuna works with are Clio users, because Clio works so seamlessly with Xero. The integration allows all client bills and invoices to automatically enter into the Xero system, saving you from having to export and import everything periodically.
But, Kahuna also works with Freshbooks and Rocket Matter as well. For Rocket Matter users, you can export your invoices into CSV files and import them into Xero.
How Kahuna Accounting Works With Small Law Firms
If you're looking to outsource your firm's accounting with Kahuna, they have a quick onboarding process to migrate all of your current accounting data to Xero.
With Xero, you'll first log in wherever you are (anywhere in the world since it's a cloud-based app) and work with Kahuna to give their team a login.
Then, Kahuna does your bank reconciliations. Xero has live bank feeds so every bank transaction is automatically recorded in Xero. The only thing left to do is reconcile the bank activity with the appropriate transaction. That needs to be matched with an invoice in Xero. Kahuna finds the payment and the invoice, marks it as paid, and reconciles it. If you have an expense, the expense shows up at the bank. The only work for the law firm is that they have to get their bill into Xero, either by scanning and dragging into Xero file sharing system or Xero's mobile app so you can upload it. Once everything is reconciled, the firm's reports and financials are up-to-date and current. Every month Kahuna provides clients with reports – cash statement, income statement, P&L, so the client can look forward.
Deming said, "Attorneys and entrepreneurs usually end up looking back a lot. We can give them real-time information so they can be more proactive."
My immediate concern was – well, how involved does the attorney need to be? How much of this is really outsourcing.
"Basically the attorney's role is to get the receipt into Xero, and we do the rest," said Deming. I have yet to try out Xero, but am very curious to see how easy this process is. Xero does make an app, allowing you to upload receipts and manage your cash flow.
Before recently, I didn't know this service was available. I figured all attorneys would need local CPAs.
"When we talk to people, the common reaction is, 'I didn't even know this was an option.' The fact that they can outsource bookkeeping work to a professional, and pay a fixed flat monthly cost is surprising. They wouldn't have realized that was even possible."
Let's cut to the chase – how much does this cost?
Kahuna prices its packages based on firm size. A solo can expect to pay around $200 per month, with a larger firm spending around $750 per month and up.
What's the biggest challenge for Kahuna?
"One challenge is that some attorneys are resistant to change," said Deming. "Sometimes an attorney will agree that Kahuna would save time and money, but they feel unable to move out of their current situation. The point we really emphasize is that it's really not hard to change. To transition into Xero takes 1-2 weeks, with most of the work being done by our accounting team, while the attorney continues their normal workflow. Whether it is Quickbooks, or some combination of spreadsheets and an accounting system, we can create your financials from bank statements and your invoices."
Kahuna Accounting and Xero will be at the Clio Cloud Convention, September 22-23 in Chicago, IL.


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The West Virginia plan is a 3 bedroom, 2 1/2 bath split level with 1804 finished sq. ft. and a 448 sq. ft. unfinished basement. A warm and spacious living room/kitchen welcomes your home on the main level. A few steps away is a large great room on the lower level. The master suite features a large master shower and a generous walk in closet. 3 car tandem garage completes this lovely home
Back Range/Snow Capped, Foothills View
Eat-in Kitchen, Separate Dining Room, Open Floor Plan, Pantry, Walk-in Closet, Washer/Dryer Hookups
Electric Range/Oven, Self-Cleaning Oven, Dishwasher, Disposal, Smoke Alarm(s)
Wood/Frame, Stone, Composition Siding
Partial Basement, Unfinished Basement


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3 Tips for a Successful Life After Graduation
Graduation is coming (or here)… that's right, like the Night King and the changing of a season there's no escaping it. When the winter comes what will you do? We're not saying the real world is a metaphor for unadulterated evil, but we are saying this change is inevitable, a little bit scary, and what comes next is something new AND exciting.
That said, here are few tips from our team that have helped us thrive IRL…
1. Stay Connected
"I hang out with a lot of the people I did when I was in high school, when I was in college, and I have a strong unit of people around me, whether it be friends or family, and if my head gets too big, they will definitely check me immediately."
-John Cena
As you move on from college life into starting a career, you aren't going out all on your own. Your relationships with your friends and family evolve into professional ones, and even better in many cases you continue to grow together.
Best practice is to be prepared. Connect with your classmates via LinkedIn and celebrate their success, offer help when they face challenges, and make introductions for them to others when it makes sense. You never know where your professional lives will take you, and it's these people that can be just the right teammate at the most challenging and exciting times—both are better with each other.
Building that team or network as you go is all about meaningful connection. Always take minute to reflect on memorable qualities and simple characteristics—write these all down. Keep the connection alive in a way that makes the most sense for them, a text every once in a while, LinkedIn connection, Email, etc.
2. Don't Stop Learning
"The willingness to keep learning is, I think, the most important thing about trying to be good at anything. You never want to stop learning."
-Emile Hirsch
Look, the learning has just begun, and for the most part the only thing you're an expert in is learning—you've been in school for most of your life at this point. Embrace that quality and don't close the door on your education with a new degree—you know nothing.... It might feel like you've been training for your career for forever, you're actually just a beginner (in fact, in the world of work we're all beginners). The best part, from now on you own it all and every opportunity to learn is ultimately defined by you. It's pretty simple: ask questions, read articles, and most importantly, WATCH and LISTEN to how those around you perform their jobs.
3. Don't Worry If It's Awkward at First
"Embarrassment and awkward situations are not foreign things to me."
-Paul Rudd
Starting a new job is hard—this won't change. Just like your first day on campus, you'll need to adjust and find people to eat lunch with, but if you stay open to the new opportunities, you're going to be great. Recognize that it's normal to feel out of place in a new environment, but everyone's been in your shoes and no one expects you to be perfect from day one.
Well, how'd we do? Do you feel ready to take over the working world? Let us know in the comments below, and feel free to share these tips with anyone else who might need them.


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2018 VIPCA Awards
Virgin Islands Professional Charter Association Yacht Show Winners
Here are the recent winners from the 2018 St Thomas Charter Yacht Show!
The H2O Yachts team had a blast visiting with all these yachts!
Best Yacht Over 52′
Best Crew Over 52′
Best Themed Yacht- Catamaran Le Reve
Experience the art of living aboard Le Reve, an owner's edition of the Essence line that is the epitome of luxury. We were extremely impressed with Le Reve at this year's USVI yacht show, so we were not surprised they took home 3 prestigious prizes!
Best Yacht Under 52′
Best Captain Morgan Cocktail- Catamaran Island Hoppin
ISLAND HOPPIN' is a brand new 2018 Lagoon 520 and is available for charter in the Virgin Islands. Congratulations to Island Hoppin for winning Best Yacht Under 52′ and Best Captain Morgan's Cocktail!
Best Yacht Runner Up Over 52′- Catamaran Shangri La
Award Winning Yacht: 2018 USVI Charter Yacht Show – Best Yacht Runner Up Over 52′
Award Winning Chef: 2018 USVI Charter Yacht Show – 1st Place Appetizer & 2nd Place Entree in Culinary Competition
Beautiful new Lagoon 52 SHANGRI LA offers luxurious accommodations and world-class service
Best Yacht Runner Up Under 52′
Best Crew Under 52′- Catamaran Starfish
The H2O Yachts vacation team was lucky enough to join Captain Sam and Chef Jen for a brief lunch during the 2018 USVI Yacht Show. What a dining pleasure!
Sam and Jen on Starfish were quite the superstars at this years USVI Charter Yacht Show. They won awards for Best Yacht Runner Up Under 52′ and Best Crew under 52′! I visited them both for lunch and during the yacht hop. They were great hosts! For the yacht hop Jen made smoked salmon deviled eggs. My Yum! (Yes, I'm from the south). She also made a special sweet cocktail that was just right!
Best Tender- Catamaran Blue Gryphon
Our H2O Yachts team was delighted to be invited aboard Blue Gryphon for a gourmet alfresco lunch with her outstanding crew while attending this year's St Thomas Boat Show!
Culinary Competition
Ist Appetizer- Daniela Drescher- Shangri La
2nd Appetizer- Mecheala Kremer- Flotation Therapy
1st Entree- Johann Roebert- Lady Sharon Gale
2nd Entree- Daniela Drescher- Shangri La
1st Dessert- Katie Saunders- Yes Dear
2nd Dessert- Juliana Leone- Tabula Rasa
Honorable Mention- Kristi Marquart- Genesis
CYAB Save The Blue- Water Competition
1st- Blue Pepper
2nd- Anastasia
3rd- Genesis


text: Antecedent Posted August 13 I thought I was getting headaches when there were solar flares because they seemed to coincide, but it turns out I was just spending too much time using my smartphone! Which way do you put the toilet paper? (assuming you have a thingy to hang it on.. we don't!) Quote Share this post Link to post Share on other sites


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Marking Talk
News and events on the happenings at Excelsior Marking as well as in our industry
Flexo Platemaking – Take Printing to a New Level
ULTRA-E HD platemaking will take your flexo print to ULTRA HIGH levels. Combining industry leading 4800dpi imaging, innovative flexo dot screening and skilled flexo prepress professionals, ULTRA-E HD will improve your print color and clarity instantly. Using proven...read more
Office Signs… Color, Contrast and Legibility
Office Signs provide several important functions. Three of the most important are: Provide Information. What? Provide direction. Where? Tell the story. Who? So how do you decide what your office signs should look like? Three considerations are Color,Contrast...read more
Thank You for Your Service!
How do you recognize your staff? One study* indicates companies with effective employee recognition programs have a 31% lower voluntary turnover than those without. The same research found that organizations that recognize employees have better employee...read more
Trends in Technology – Hand Held Printers
The ability to identify a product with a specific mark or brand has become increasingly important. Marking allows quick asset identification, as well as, provides brand awareness. Businesses needing to mark products and/or assets, generally ask for faster, more...read more
Excelsior Marking Awarded Excellence in Business Award
We are proud to announce this news....read more
Do You have a Smoke Free Workplace?
Many organizations have decided to make their workplace and campus "Smoke Free". Although employers know this is best, it can be challenging.Most people are aware of the dangers of smoking - they don't need a lecture. Restricting people from a habit, like smoking,...read more
ADA/Braille Sign Guidelines
ADA/Braille Sign Guidelines Explained As a part of The American Disabilities Act (ADA) specific building Signage requirements are defined. Signs must conform with color and contrast; Braille and Tactile; and Installation rules. Here are a few of the main points to...read more
Changes in Labeling Requirements
Food manufacturers have until July 26, 2018 to comply with the new FDA nutrition facts labeling requirements.read more
You don't always see the words "manufacturing" and "charitable" in the same sentence. Some think of manufacturing companies' as impersonal, work horses. You may think of a large, cold, warehouse type building cranking out metal parts. However, the workers, in...read more
Building your Brand with Signage
The last couple of conversations I've had with customers I was asked the same question "Is there an easy way to update and coordinate our Office Signage to reflect my company Brand?" The reason for the question is evident as I look down the hallways. There are...read more


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Here you'll find the latest discount codes, coupons, savings, & promotions from Apple.
Everyone knows how hard it is to come across an Apple sale or discount. Allow us to take the guess work in all of your searching.
Below, there is a list of all of the current promotions offered by Apple, so we highly encourage you to check them out if you want to save money on your next Apple purchase.
They are always sending out new promotions, so always check back to see what's new.
Note: Check out the following cards to earn one of the best flat cash back opportunities across all purchases: Wells Fargo Cash Wise card, the Chase Freedom Unlimited card, or the American Express Cash Magnet card! For a wider variety, see more credit card bonus offers here.
See our best bank bonuses updated daily to earn up to $1,000 in free money. Find popular checking offers such as Chase, Discover, Huntington, and TD Bank. See our best rates for Savings and CD too.
|Chase Total Business Checking®
|$200 Cash
|Chase Total Checking® + Chase SavingsSM
|$350 Cash
|Chase Premier Plus CheckingSM
|$300 Cash
|Discover Bank Online Savings
|$200 Cash
|Simple High-Yield Checking
|$500 Cash
|Chase College CheckingSM
|$100 Cash
|TD Bank Checking
|$300 Cash
|Discover Cashback Debit Account
|$360 Cash
|Huntington Bank Business Checking 100
|$200 Cash
|Huntington Bank Unlimited Business Checking
|$400 Cash
Table of Contents
About Apple
Apple Inc. is an American multinational technology company headquartered in Cupertino, California, that designs, develops, and sells consumer electronics, computer software, and online services. Built with a sleek and elegant design, Apple products are for the average person with beyond average needs.
Current Apple Promotions
Free 4-Months of Apple Music
Wondering if Apple Music is worth it? Well now you don't have to. There is currently a promotion for new users only where you can get 4 months of Apple Music for free when you enroll through Groupon. Hurry to take advantage of this promotion while supplies last!
- Offer expiration: Limited Time Offer
- What you'll get: Free 4-Month Apple Music Subscription (Family or Individual Plan)
- Who is eligible: New Users Only
- Where it's available: Groupon
- How to earn it: Head to Groupon to enroll for an Free 4-Month Apple Music Subscription
(Click the link above to enroll for an Apple Music subscription)
Free Beats Headphones – Students
Attention all students! If you head over to Apple right now you can score special back to school prices on any Macbook and iPads! Plus receive a free pair of Beats headphones with your purchase!
- Offer expiration: For a limited time
- What you'll get: Free pair of Beats Headphones, see full list below.
- Who is eligible: Students with valid school ID's
- Where it's available: Online, in-store
- How to earn it:
- Purchase eligible Mac or iPad products
- Valid Beat products: Beats Studio3 Wireless Over-Ear Headphones, Beats Solo3 Wireless On-Ear Headphones, or BeatsX Earphones
(Click the link above to purchase valid products)
Up to 50% Off
Right now, eBay is offering big savings on Apple products! Stock up for back to school shopping with some new tech, while supplies last.
- Offer expiration: For a limited time
- What you'll get: Up to 50% Off on iPhones, HomePods, and more
- Who is eligible: Anyone through eBay
- Where it's available: Online eBay
(Click the link above to purchase )
Free Apple Camp for Kids Ages 8–12 (Expired)
With dates going through August 3, 2019, Apple is offering Free Apple Camp for Kids Ages 8–12. Through creativity, your child will be able to create their own dream park, song, direct their own movie, and learn a little bit of coding! Keep in mind that this is event is subject to availability, so sign up before the dates are all filled.
(Click the link above to learn more about Apple Camp)
Bottom Line
Even if you're not a fan of Apple products, you've got to appreciate the beauty behind the product. A large number of people from students to professionals utilize their products in their everyday life to boost their productivity.
If you're an Apple fanatic, keep this post saved because whenever there is a new deal or promotion, we will update this post to make sure you save money on your next purchase. Interested in posts like this? Be sure to check out our list of the Best Gift Cards and be sure to use a Rewards Credit Card, all on HMB!
|Chase Total Business Checking®
|$200 Cash
|Chase Premier Plus CheckingSM
|$300 Cash
|Chase Total Checking® + Chase SavingsSM
|$350 Cash
|Simple High-Yield Checking
|$500 Cash
|Discover Bank Online Savings
|$200 Cash
|Chase College CheckingSM
|$100 Cash
|You InvestSM by J.P. Morgan
|$625 Cash
|TD Bank Beyond Checking
|$300 Cash
|TD Bank Convenience CheckingSM
|$150 Cash
|Discover Cashback Debit Account
|$360 Cash
|Huntington Bank Unlimited Plus Business Checking
|$750 Cash
|Huntington Bank Unlimited Business Checking
|$400 Cash
|Huntington Bank Business Checking 100
|$200 Cash
|UFB Direct High Yield Savings
|CIT Bank Savings Builder
|Betterment Everyday Savings
|$2,500 Cash
|Ally Invest
|$3,500 Cash
|TD Ameritrade
|$600 Cash


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Boy, I am so glad the weekend is here! It gives me a chance to unwind, go to the park, spend time with my fur babies, and best of all – read a book or two! This week, my book haul was a bit smaller than usual, but it's still a good one 🙂 All the books in this week's mailbox were FREE! Here are this week's pretties:
Special thanks to Bloomsbury Children's Books and Thomas Nelson Fiction for the eGalleys! Also, thank you to Barnes & Noble for such great Free Friday selections 🙂 Have I mentioned how much I love my NOOK?!
I am very excited to read all of these, and even more excited to participate in a Blog Tour for Angel Eyes in a couple of months. I've also seen some positive comments floating around about The Académie, and am positive it will be a fun read.
So, that's it for the week! What was in your mailbox this week?
Leave some "comment love" below, and link to your IMM post, so I can stop by and check out your goodies 🙂
Happy reading, dear reader!


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Setting up your own family office will be the first step in succession planning, but how to do it? There are a lot of different tools in the market; not to mention the complication of many service providers who claim to know what to do. It can be very confusing to make a decision.
But this shouldn't be an excuse for not taking any actions. Give us a call and we are happy to further discuss with you on your wishes and provide a tailor-made solution.


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Each club hosts one Trap Shooting event a year. Shoot year starts in June. Each shoot consists of 50 sixteen yard targets and 50 handicap targets. Only the top five scores from each club are counted. Each club receives one additional point for each club member shooting. An annual rotating trophy goes to the club with the most shoot wins for the year. A trophy for each high shooter in men's, women's, and junior categories is awarded at each shoot.
Who: Members from participating clubs and guests.
When: To Be Determined
Cost: Approx $30.00
For Additional Information Contact:
Shootmaster Ken Jossenberger firstname.lastname@example.com.
Current club members and current host month:
Lemon Grove Rod and Gun, June
Escondido Fish & Game, August
Lakeside Sportsmen's Club, October
Imperial Valley Rifle & Pistol Club, February
Maywood Trap Club, March
Copyright © 2019 lemon Grove Rod and Gun Club - All Rights Reserved.
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X‐ray crystallographic studies reveal that the incorporation of spacer groups in carbonic anhydrase inhibitors causes alternate binding modes
Human carbonic anhydrases (CAs) are well studied targets for the development of inhibitors for pharmaceutical applications. The crystal structure of human CA II has been determined in complex with two CA inhibitors (CAIs) containing conventional sulfonamide and thiadiazole moieties separated by a —CF2— or —CHNH2— spacer group. The structures presented here reveal that these spacer groups allow novel binding modes for the thiadiazole moiety compared with conventional CAIs.
No References
No Citations
No Supplementary Data
No Article Media
No Metrics
Keywords: carbonic anhydrase inhibitors; fluorine hydrogen bond; sulfonamide
Document Type: Research Article
Publication date: July 1, 2006


text: Earlier this year Russian President Vladimir Putin proposed a reset of relations between the United States and Russia across all major branches of government, BuzzFeed News reported on Tuesday. According to documents detailing the proposal, a Russian diplomat asked the U.S. State Department for an immediate restoration of the diplomatic, military, and intelligence channels that had been severed after Russia intervened in Ukraine and Syria. The documents reportedly show a proposal for several meetings between the two countries to discuss areas of mutual interest. "It just ignores everything that caused the relationship to deteriorate and pretends that the election interference and the Ukraine crisis never happened," said Angela Stent, a former national intelligence officer on Russia during the George W. Bush administration. "When the Russians submitted this proposal, they were under the impression that Trump would do what he said he would do: Make a deal with Putin and normalize relations."


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October 2, 2018 – HCAP Partners announced today that Fortive Corporation (NYSE: FTV) has acquired Accruent, Inc., a leading provider of physical resource management software, for approximately $2.0 billion in cash.
HCAP Partners Announces Exit of Portfolio Company Lucernex
Lucernex is Vindicated. Texas Court Dismisses All Claims Due To Lack Of Evidence.
September 19, 2016: HCAP Partners' portfolio company, Lucernex, announced that a Travis County Judge has dismissed with prejudice every claim Accruent made against Lucernex. The judge's ruling reaffirms that Lucernex conducts business with integrity and did not engage in any unfair business practices.
HCAP Partners Announces Investment in Lucernex
July 18, 2016: HCAP Partners announces an investment in Lucernex, Inc. The investment will further fuel the growth that Lucernex has experienced as more of the world's leading retailers, restaurants, healthcare providers and financial services firms adopt its cloud-based Integrated Workplace Management System (IWMS) and Store Lifecycle Management (SLM) solutions.


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The Greatest Small Enterprise Opportunities
House painting is a ability that most individuals can pick up fairly simply. You may as well do focused advertising and marketing of your companies and merchandise. Success for this firm builds on systematic improvement of a world class production process, bringing high quality products to the market and working close in a mutually helpful approach with major chaebols.
You would possibly even hire an outside advertising and marketing marketing consultant to guage and possibly argue with the mum or dad firm's selection. If you are uninterested in earning money for others and dream of working a corporation of your personal, it's essential to consider and consider the enterprise alternatives available in franchising.
It's preferable that the scholars have some practical entrepreneurial or advertising and marketing experience, but this is not obligatory. They're in two categories; for starter marketer and for skilled marketers. Furthermore, Nordic residents report a high degree of willingness to alternate information for new companies, making the area an opportune marketplace for launching new data-pushed providers.
In this report we clarify the differences between a franchise and a enterprise alternative and enable you determine what your choices are if you resolve entrepreneurship is for you. four. The initial price paid to the seller with a view to start the enterprise opportunity should vary between $four hundred and $1,000.
Affiliate Advertising: Earn commissions once you send customers to different companies web sites. I have bought their merchandise many times since 1998. There are several websites online that provide the ability to look through a database of traders that might doubtlessly supply cash to start a enterprise.


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Sales Have Ended
Event Information
Date and Time
Refund Policy
Refunds up to 7 days before event
Sales Have Ended
Learn how to set up and implement your LinkedIn marketing, using relevant case studies and hands on practice.
LinkedIn is still the prominent business to business global network which 39.6% of Singaporeans use on a daily basis (eMarketer 2018) and is the only social media channel permitted in China. It's important to understand how to use this network to reach out to customers, influencers, affiliates and partners in order to grow your business.
Our course will give you an overview of how your organisation can use LinkedIn as part of your marketing mix to attract new customers and showcase your brand. The course will include tips on how to set up and implement your LinkedIn marketing, using relevant case studies and hands on practice during the session.
As this is a hands-on course, participants will need to bring their laptops.
Course Fees:
- S$80 per participant (exclu GST)
- Exclusive $10 discount to NTUC Members or Econsultancy Paid Subscribers (kindly email email@example.com with your Full Name and NRIC/FIN to get your exclusive promo code)
NTUC members can claim up to 50% of course fees through UTAP. More information can be found here.
Econsultancy courses in APAC are delivered in partnership with ClickAcademy Asia.
Click here for ClickAcademy Asia's Refund Policy.
Trainer Info
Elizabeth Taylor (Senior Trainer, Econsultancy)
Liz worked in the entertainment industry for 12 years on film launches such as Harry Potter, Fast & Furious and Mamma Mia. During this time she gained a wealth of experience in marketing, including advertising, promotional planning, trade marketing and marketing communications. The latter was predominantly focused on digital media and how to use new and emerging platforms to engage with consumers.
Liz took a maternity break, during which time she completed her Masters in Social Media Marketing, and then decided on a career change to professional academia. Liz is now focused on teaching and supporting students for Marketing qualifications and supporting local businesses with marketing consultancy services. Liz has worked for the University of Hertfordshire, delivering their undergraduate courses, and the level 4 and 6 CIM qualifications. She has now worked as a tutor for 8 years, and has experience in supporting students across a range of postgraduate and university qualifications.
If you have any questions about the course or payment, please email email@example.com (call: 6909 9150)
Date and Time
Refund Policy
Refunds up to 7 days before event