text: This wine faults something like that sulfurous off and is referred to the cause as "light taste". Mostly, it occurs in bottled wines and is caused by exposure to light (especially daylight but also artificial light), with wines in particular in bright bottles are at risk. Cause is UV light That's why wines in dark bottles are also better protected. At risk are wines with high protein content, The wine smells like cheese, the taste is stale and putrid. A fight takes place as in Böckser copper sulphate or silver chloride, Similar mistakes are protein haze. Lindton and Lactic acid sting,


text:
Cbus Property and ISPT are proud of to announce 1 William Street, Brisbane has been awarded the Property Council of Australia's Rider Levett Bucknall Queensland Development of the year. The landmark commercial tower has reshaped the Brisbane skyline, heralding a new era of development having achieved the most honourable property award in Queensland.
We are creating the first urban park in the central city since City Square was developed in 1980. The new park, located on Market Street, will create 1900 square metres of new public open space in the central city.

subset: commoncrawl


text:
How To Achieve Cross-Browser @font-face Support
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Director of Statistical Programming
- Employer
- AbbVie
- Location
- Lake County, IL, US
- Posted
- May 26, 2019
- Ref
- 1903014
- Discipline
- Clinical, Clinical Biostatistics, Information Technology, Software Development, Science/R&D, Biostatistics
- Hotbed
- BioMidwest, Ideal Employer
- Required Education
- Masters Degree/MBA
- Position Type
- Full time
Candidate will be responsible for leading and directing the statistical programming strategy for multiple clinical projects across all therapeutic areas through own effort and those of their staff. You will provide training and performance management for staff and assist management in resource
estimation and resource management.
- SAS Programming: Demonstrated extensive understanding of SAS programming concepts and techniques appropriate to the pharmaceutical industry. Able to critically review programming techniques and strategy. Recognizes limitations in programming strategy and
corrects flaws proactively.
- Standards: Monitors and interprets industry/regulatory trends and regulatory guidance. Sets both short and long term vision for programming standards. Ensures programming standards work seamless with related function's standards.
- Database Activities: Case report forms and database definitions: Provides strategic guidance on the development of CRFs and database designs. Provides strategic guidance on global standards related to CRF designs and database designs.
- Derivation Programming, Submission Data Sets and Programs: Demonstrated proficiency in interpreting statistical analysis plans and developing analysis data set specifications. Monitors and interprets industry/regulatory trends and regulatory guidance. Sets both short and long term vision for programming standards
- Client Interaction: Works collaboratively with multiple stakeholders to manage priorities and resources across therapeutic areas. Builds relationships with external partners and service organizations. Demonstrates an understanding of drug development principles. Anticipates potential problems within and across projects and develops appropriate contingency plans. Creates escalation plans to ensure resolution of all issues at the therapeutic and project levels.
- Communication: Effectively and persuasively presents statistical programming concepts, assessment of risks and impacts and logical arguments to other statistical programmers, statisticians, scientists and non-scientists. Effectively presents information through planning and execution of meetings and presentations.
- Training and Mentoring: Provides coaching and mentoring to first line managers when needed. Provides strong professional and technical leadership to maintain highly motivated staff. Arranges appropriate training opportunities for staff to facilitate their timely career development. Ensures consistency of training opportunities across the organization. Ensures that self and staff are compliant with training requirements.
- Resource Management: Manages statistical programming staff by appropriate assignment of responsibilities, defining scope and reviewing activities/progress so that projects are delivered on time with suitable quality. Allocates resources to projects such that the correct balance of expertise and experience is maintained for all projects. Responsible for assisting the Global Director of Statistical Programming in preparing global resource planning.
- Establishes high expectations and goals to ensure organizational success and leads staff to meet or exceed those goals. Creates an organization that executes efficiently and is committed to meeting goals. Encourages a culture of open, honest communication where all are encouraged to express their views.
Level will be based on education & years of experience.
- MS in Statistics, Computer Science or a related field with 12+ years of relevant experience OR BS in Statistics, Computer Science or a related field with 14+ years of relevant experience.
- High degree of technical competence and communication ability, both oral and written. Highly competent in SAS programming and Macrodevelopment. Pharmaceutical experience with clinical trials, including familiarity with expectations of regulatory agencies, especially FDA and EMEA. NDA/BLA or other regulatory filing experience, including ISS or ISE experience. Thorough understanding of ICH Guidelines and relevant regulatory requirements.
- A minimum of 5 years of management experience required.


text:
Customize your JAMA Network experience by selecting one or more topics from the list below.
To compare the growth profiles of infants and young children born small for gestational age (SGA, <10th percentile birth weight for gestation) or large for gestational age (LGA, ≥90th percentile) with those appropriate for gestational age, and to document the expected growth patterns through early childhood based on national health examination survey data.
Infants and children, 2 to 47 months of age, who were born in the United States and examined using the Third National Health and Nutrition Examination Survey (1988-1994).
Main Outcome Measures
Measurements of growth status based on normalized distributions (z scores or standard deviation units [SDUs] for weight, length, and head circumference.
Prevalence rates were as follows: SGA infants, 8.6%; appropriate for gestational age infants, 80.9%; and LGA infants, 10.5%. Infants who were SGA appeared to catch up in weight in the first 6 months, but thereafter maintained a deficit of about −0.75 SDUs compared with infants who were appropriate for gestational age. The weight status of LGA infants remained at about +0.50 SDUs through 47 months of age. Length and head circumference were also associated with birth weight status, averaging over −0.60 SDUs for SGA infants and +0.43 SDUs for LGA infants.
Birth weight status is related to growth rates in infancy and early childhood, which underscores the importance of considering child growth relative to birth status when using growth charts. Small for gestational age infants remain shorter and lighter and have smaller head circumferences, while LGA infants grow longer and heavier and have larger head circumferences.
INFANTS WHO are born growth restricted or small, based on low birth weight for gestational age status, generally show some compensatory growth (catch-up) in the first year, although most catch-up occurs in the first 6 months.1-6 The growth of large for gestational age (LGA) infants is thought to slow down in infancy.2,4 However, in both of these extreme cases, after an initial period of growth compensation, the growth deficit or surfeit is expected to persist. The tendency of birth weight to determine growth status throughout childhood has been demonstrated in several studies of large groups in the United States,7-10 but the extent to which early growth is associated with fetal growth adjusted for length of gestation has not been shown for an ethnically diverse sample of infants and young children born in the United States. There has been more interest in this relationship in recent years because of new techniques in prenatal diagnosis and neonatal care that allow the survival of infants at the extremes of the spectrum in birth weight. The early growth of infants born at the extremes of birth weight may be best evaluated by considering their birth status.11,12
The Third National Health and Nutrition Examination Survey (NHANES III, 1988-1994),13 a nationally representative, cross-sectional health examination survey, anthropometrically measured a sample of infants and children from the United States 2 months of age and older. This study produced the largest national data set available on infant and child size for subjects between the ages of 2 and 47 months. The objective of these analyses was to compare the growth profiles of infants and young children born small for gestational age (SGA, birth weight <10th percentile for gestational age) and LGA(≥90th percentile) with those of normal birth weight children (appropriate for gestational age, AGA) to document the expected growth patterns through early childhood based on NHANES III data.
The measurements on infants and children were obtained from NHANES III, conducted by the National Center for Health Statistics, Centers for Disease Control and Prevention (NCHS/CDC), Bethesda, Md, from 1988-1994.13 The NHANES III included approximately 40,000 people, aged 2 months and older, who were representative of the US civilian, noninstitutionalized population. The analyses reported herein focus on non-Hispanic white, non-Hispanic black, and Mexican American infants and young children ranging in age from 2.0 to 47.99 months. The anthropometric measurements available at ages 2 to 47 months are the largest nationally representative data set available on growth status, including weight, recumbent length, and head circumference. As part of the stratified, multistage probability design of NHANES III, infants and children aged 2 to 71 months were oversampled. Blacks and Mexican Americans were also oversampled to allow adequate sample sizes to support separate estimates; each comprised roughly 30% of the sample.
Birth certificates were sought for the US-born infants and young children born in the United States after informed consent was obtained from the parents or guardians. The birth certificate number was then linked to the demographic and medical information from the certificates stored electronically by birth year (national natality files) for the years 1985-1994 at NCHS/CDC.
There were 5566 infants and children at these ages who were examined and measured, either in the mobile examination centers or (for a few infants) in their homes. Of this number, 137 infants were foreign-born, and for these no birth certificates were sought or obtained. Birth certificates were obtained and positively matched for 5129 (94.5%) of the US-born infants and young children. Information common to the birth certificates and NHANES III (child's sex, race/ethnicity, and mother's age) was compared, and discrepancies were resolved whenever possible. Excluded from further analysis at this point were 4 cases with missing birth weights, 1 case of sex discrepancy between the certificate and NHANES III, and 118 children who were twins or triplets.
On the national natality files, the standard measure of length of gestation is that calculated in completed weeks from the mother's last menstrual period (LMP). On the birth certificates, length of gestation from the LMP was examined for completeness and validity, and cases with missing or invalid gestation from the LMP were excluded from further analysis (n = 280). Length of gestation from the LMP was missing for 113 cases (2.3%). Length of gestation was considered valid if it was between 20 and 44 weeks and birth weight was consistent with gestation. Exclusions due to invalid gestations were made for 89 cases (1.8%) where gestation was greater than 44 weeks and for 78 cases (1.5%) where, at a length of 35 weeks or less, birth weight was inconsistent with gestation from the LMP.14 No live births at less than 20 weeks were present. Clinical estimates of gestation based on ultrasonography or neonatal examination were not used to replace invalid or missing gestations from the LMP,14 since clinical estimates were not routinely reported on birth certificates before 1989. Very preterm delivery was defined as delivery before 33 weeks' gestation, preterm delivery as delivery between 33 and 36 weeks, and term as delivery from 37 to 44 weeks after the LMP.
Finally, the sample was restricted to non-Hispanic white, non-Hispanic black, and Mexican American infants and young children. Those of all other races/ethnicities (n = 295) were excluded because sample sizes were too small for analyses by age group, leaving a final analytic sample of 4431.
Infants and children were categorized by birth weight for gestational age status using reference percentiles derived for singleton infants from 1989 US Vital Statistics by Zhang and Bowes.14 Using these reference data, infants are categorized separately by race/ethnicity (white vs black) and within race by infant sex (male vs female) and maternal parity (infants of primiparas vs multiparas). Infants designated by NHANES III as non-Hispanic white and Mexican American were categorized as white, and non-Hispanic black as black, for comparison with the reference data.14 Mexican American infants were categorized using the percentiles for whites, consistent with the reference data, because their birth weight distributions, at least at the low end, were comparable with whites.15 Small for gestational age, indicating intrauterine growth retardation,16 was defined as a birth weight for gestational age below the 10th percentile; appropriate for gestational age (AGA), from the 10th to 89th percentile; and LGA, or macrosomia, at or above the 90th percentile.
Using these definitions, the infants categorized on the basis of their birth weight for gestational age status at the extremes do not entirely coincide with infants classified at the extremes based on birth weight alone. Infants born SGA, especially those at term, are not necessarily low birth weight (LBW) (<2500 g), and LGA infants are not necessarily macrosomic (≥4000 g) by size criteria.
For analysis, the infants and children were grouped by chronological age (CA): 2.0 to 5.99 months, 6.0 to 8.99 months, 9.0 to 11.99 months, 12.0 to 23.99 months (1 year), 24.0 to 35.99 months (2 years), and 36.0 to 47.99 months (3 years), based on age at examination.17 Infants younger than 12 months were divided into 3 groups to more clearly identify rapid growth changes characteristic of infancy. The infants and children were also grouped by gestation-corrected age (GCA).11,18,19 Gestation-corrected age was calculated as age in months, adjusted for length of gestation, using the following algorithm: for those born at 21 to 24 weeks' gestation, GCA = CA (in months) −4; at 25 to 28 weeks, GCA = CA (in months) −3; at 29 to 32 weeks, GCA = CA (in months) −2; at 33 to 36 weeks, GCA = CA (in months) −1. Using this algorithm, 9 infants were excluded from analyses using the GCA groups because their GCA was 1 month or younger and fell below the age limit for the youngest group, and 1.4% of the sample (64 of 4431) was reclassified into a contiguous younger age group. The GCA groups were used in separate analyses to determine if there was an effect of growth restriction or acceleration independent of degree of prematurity.
The anthropometric measurements considered were body weight (kilogram), recumbent length (centimeter), and head circumference (centimeter). Because the distribution of anthropometric measurements, particularly weight, can be skewed and because the timing of growth velocity varies in infancy and childhood, the anthropometric variables were transformed to allow for comparison across CA cohorts. Body weight was first transformed to an approximate normal distribution using a power transformation of −1/√x.20,21 To control for group differences and to scale the values for comparison across age groups, the anthropometric variables were then converted into z scores (SD units [SDUs]) within the sample chronological age, sex, and race/ethnicity groups.17
Because the distributions of the anthropometric variables were approximately normal, percentiles corresponding to the z scores can be determined using the area under the normal curve. A z score or SDU of 0 represents the median (50th percentile). A z score of −0.50 would fall at the 31st percentile for the sample and +0.50 at the 69th percentile; the 10th and 90th percentiles are −1.28 SDUs and +1.28 SDUs, respectively. However, the magnitude of the absolute effect in actual measurement units for a positive SDU is larger than that for comparable negative SDU for skewed distributions such as body weight.
Other variables used in analysis were obtained both from the birth certificates and NHANES III. Maternal parity and infant birth order were determined from the number of previous births reported on the birth certificate. To exclude twins or triplets, plurality of birth was recorded from the birth certificates.
Race and ethnicity were based on self-reports from NHANES III, using US Department of Commerce Bureau of the Census categories.13 Information on maternal smoking during pregnancy and whether the infant received special care at birth were obtained from the questionnaire administered to the infant's parent or other respondent in the home. Maternal smoking during pregnancy was considered because smoking during pregnancy has an effect on fetal growth and infant size at birth and has possible effects on postnatal growth.22,23
Sample weights were used to account for the oversampling and unit nonresponse. SUDAAN software,24 which uses a Taylor series expansion to adjust variance estimates to account for the sample design, was used to estimate SE of the descriptive and prevalent characteristics. Analyses across age groups were accomplished using SUDAAN regression procedures. To estimate the effect for each CA or GCA group, separate indicator variables were created for SGA and LGA for each age group and entered into a regression with AGA infants and children as the reference group and the anthropometry z scores as the dependent variables. Summary effects for birth weight status were estimated accounting for group effects in the models predicting the anthropometry z scores. Results from the models are regression coefficients (±SE) in SDUs, tested for statistical significance (α=.05) from 0.
The overall prevalence of SGA in this sample was approximately 9% (n = 423); 81% (n = 3570) were born AGA, and 10% (n = 438) were born LGA. There was a relatively consistent distribution of birth weight status both by CA group and race/ethnicity. However, Mexican American infants were somewhat underrepresented in the LGA category compared with non-Hispanic white and non-Hispanic black infants (Table 1). There were more female than male infants born either SGA or LGA.
Very preterm (15.1%) and preterm (12.0%) infants were disproportionately SGA. At the same time, 9.2% of preterm infants were actually LGA (Table 1). However, the overall prevalence of very preterm delivery was only 1.1% ± 0.2% (n = 49), and 5.8% ± 0.5% (n = 318) were preterm. Within the weighted sample of SGA infants, 1.9% ± 1.0% were born very preterm and 8.1% ± 2.4%, preterm. There were no LGA infants born very preterm, and only 5.1% ± 1.1% of the LGA infants were preterm.
As expected, LBW infants were disproportionately SGA (59.1%), and macrosomic infants were likely to be LGA (86.2%), but there was some discordance . Of the infants categorized as SGA, almost 64% (63.9% ± 2.8%) had birth weights at or above 2500 g; only 36.1% ± 2.8% of the SGA infants were actually LBW. No SGA infant was macrosomic. Among AGA infants, only 2.7% ± 0.3% were LBW, and 1.6% ± 0.3% were macrosomic. On the other hand, while no LGA infant was LBW, 22.6% ± 2.8% of infants classified as LGA had birth weights less than 4000 g, and 77.4% ± 2.8% of the LGA infants had birth weights at or above 4000 g.
Almost 15% of the infants of mothers who smoked during pregnancy were SGA, compared with 7% of the infants of nonsmoking mothers. On the other hand, less than 5% of the infants of mothers who smoked were LGA, compared with 12% of the infants of nonsmoking mothers (Table 1). Of those who required special care at birth, ie, admission to neonatal intensive or transitional care facilities, 18% were SGA, but the vast majority were AGA (73.3%).
Birth weight is significantly associated with body weight through age 47 months, although there seems to be catch-up and slowdown during the first 6 months (Figure 1 and
Table 2). By definition, the weights of SGA infants were below −1.28 SDUs at birth (<10th percentile); the coefficient for the group at 2 to 5 months was −0.87 SDUs (19th percentile) and the coefficient at 6 to 8 months was −0.72 SDUs (24th percentile). There was little change in the magnitude of the coefficients thereafter (Figure 1). Compared with NCHS reference data,25 this translates into an average deficit of 2 kg below the median at age 47 months for SGA infants.
Regression coefficients (±SE in SD units [z scores] for body weight for infants and children born small for gestational age (▪) and large for gestational age (♦) compared with infants and children born appropriate for gestational age (z score = 0). The value at chronological age 0 (birth) represents the assumed z score for weight at birth (−1.28 for small for gestational age, +1.28 for large for gestational age) based on the defining criteria of birth-weight-for-gestational-age (<10th percentile for small for gestational age, 90th percentile for large for gestational age). All points are statistically different from 0 at P<.001.
Showing comparable slowdown, the coefficients for weight of LGA infants fell from above 1.28 SDUs to remain at about 0.50 SDUs (69th percentile) for the groups later in infancy and early childhood. For LGA infants, this means that they average about 2 kg above the median at 47 months.25 For both the SGA and LGA infants, not only were the regression coefficients summarizing across all ages significant for weight (P<.001), but the coefficients for each age group were highly significant (P<.001) as well (Table 2).
Comparable trends were seen for recumbent length (Figure 2 and Table 2) and head circumference (Figure 3 and
Table 2), although some cohort effects were apparent due to sample variability. There was continued tracking, but it was impossible to determine the extent of change in the first few months of life because no baseline data on length and head circumference at birth were available on the birth certificates. Again, compared with median reference data,25 at 47 months, SGA infants should be approximately 3 cm below the median and LGA infants 2 cm above the median in length.
Regression coefficients (±SE in SD units [z scores]) for recumbent length for infants and children born small for gestational age (▪) and large for gestational age (♦) compared with infants and children born appropriate for gestational age (z score = 0). All points, with the exception of that for infants born small for gestational age at age 9 to 11 months, are statistically different from 0 at P<.05.
Regression coefficients (±SE in SD units [z scores]) for head circumference for infants and children born small for gestational age (▪) and large for gestational age (♦) compared with infants and children born appropriate for gestational age (z score = 0). All points, with the exception of that for infants born large for gestational age at age 9 to 11 months, are statistically different from 0 at P<.05.
Analyses using the GCA groups yielded almost identical results. The regression coefficients for weight and length for the CGA age groups in the first year are presented in Table 3. Only the GCA groups at 2 to 5 months of age for the SGA infants differed from the 2- to 5-month-old CA groups. For the GCA groups at 2 to 5 months of age, the coefficients for weight and recumbent length were close to −0.75 SDUs compared with −0.85 SDUs for the CA group. However, after the first several months, correction for degree of prematurity does not affect the relative growth of SGA and LGA infants in these analyses.
We have shown persistent associations of birth weight for gestational age status with growth status in infancy and early childhood through age 47 months. Despite catch-up, infants born SGA tend to remain shorter and lighter with smaller head circumferences. After an initial period of compensation, infants born SGA can be expected to remain around the 25th percentile in all dimensions through early childhood. Compared with growth charts currently in use,25 this means that at 47 months of age, children born SGA may show a deficit of at least 2 kg in weight relative to the median and a deficit of almost 3 cm in length and height. Likewise, despite a decrease in growth, LGA infants tend to remain longer and heavier with larger head circumferences. Large for gestational age infants may remain at least in the upper tertile through early childhood. For LGA infants, this means about 2 kg excess in weight and 2 cm in length/height at age 47 months.
Despite the facts that 64% of the SGA infants were not also LBW and only 10% were born preterm, SGA was consistently associated with later growth status. This is undoubtedly because the factors that restrict or retard fetal growth may vary in intensity and may differ from those that are associated with preterm delivery, although there is considerable overlap in origin and recognition that infants born preterm are more likely to be characterized by suboptimal growth.26
There are a number of risk factors and underlying causes of the growth restriction, including pre-eclampsia, infection, placental insufficiency, maternal smoking, inadequate maternal nutrition, small maternal size, and low maternal weight gain.27,28 However, in most cases, decreased rates of fetal growth as evidenced by an SGA outcome seem to be an adaptation to an inadequate nutrient supply during gestation. Growth-restricted infants are characterized by fetal hypoglycemia, which acts to maintain the maternal/fetal glucose concentration gradient and transport of glucose across the placenta to the fetus. The hypoglycemia also limits insulin secretion, initially potentiating fetal glucose production, but subsequently resulting in increased protein breakdown, decreased protein accretion, and, thus, slower growth.27
Studies of the body composition of SGA infants at birth have shown that lean body mass (muscle) and bone mineral content are reduced compared with their AGA counterparts.29,30 However, much like young children after an episode of starvation or illness that causes growth to falter,4 SGA infants should have the potential to catch up in growth outside the restrictive intrauterine environment depending on the extent of the retardation. For example, the growth restriction associated with maternal smoking during pregnancy seems to be largely overcome within the first year.22,23
The need to evaluate SGA infants with reference to their birth status is a separate issue from that surrounding the growth of infants born preterm. Not all infants born early are growth restricted. Reference data from the Infant Health and Development Program (IHDP) for growth during the first 36 months (GCA) has been developed to evaluate infants born both LBW and preterm.11,19 Unlike SGA infants born at term, preterm LBW infants show limited or no catch-up at least through the first 12 months, although those born AGA and preterm do relatively better.12,31,32 This is unlike most of the findings on SGA infants, especially those born at term, for whom catch-up can be expected.
Fitzhardinge and Steven1 were among the first to look at catch-up for term SGA infants, following a sample of 131 white, singleton infants with birth weights 30% below expected values (generally < 2500 g). The average weight and height of the SGA infants rose from below the third percentile at birth to between the 10th to 25th percentile at 6 months, and remained around the 25th percentile through age 8 years. Low et al33,34 compared the growth through age 5 years of 76 white SGA infants born at term with that of 88 AGA infants (birth weight >25th percentile). The SGA infants demonstrated accelerated growth during the first 3 months, but never completely caught up, remaining smaller at age 60 months by an average of 2.3 kg and 3.6 cm.34
There have also been small, nonrepresentative studies, summarized below, that compared SGA term infants with LGA infants born at term and described the postnatal growth of LGA infants. In our analyses, LGA infants showed consistent differences in growth status through early childhood, despite the fact that 23% of LGA infants weighed 4000 g or less at birth. There are a few rare syndromes associated with accelerated fetal growth,35 but it is believed that the condition of most of the LGA infants is due to abnormalities of maternal glucose metabolism or gestational diabetes mellitus. Large maternal size, obesity, and excessive maternal weight gain are also risk factors. With gestational diabetes, the fetus is exposed to high levels of both glucose and amino acids, and the resulting fetal hyperglycemia is associated with increased insulin secretion (hyperinsulinemia) and accelerated growth of lean body mass and fat.6,36
Davies37,38 followed 51 SGA and 38 LGA infants, defined as below or above the 5th and 95th percentiles,39 respectively, compared with 100 AGA controls. During the first 6 months, there were substantial shifts to the mean in weight, but great diversity in growth pattern. Of the LGA infants, the growth in weight of 26% showed tracking from birth, while 74% showed relative slowdown. On the other side, 32% of the SGA infants remained small (less than fifth percentile), while 68% showed substantial catch-up.
In the largest comparable clinical study, Ounsted et al3,40,41 conducted a 7-year longitudinal study, enrolling a sample of 238 SGA (18 with gestational ages <37 weeks), 246 AGA (8 preterm), and 241 LGA (1 preterm) white, singleton infants. Abnormal birth weight was ± 2 SDs of mean birth weight for gestational age. In the first 6 months, actual and relative growth was greatest in the SGA group and lowest in the LGA group. Follow-up established that at 4 years3 and 7 years,41 there were still highly significant differences in height and weight among the groups. In findings remarkably similar to those presented here, at age 4 years, the children born SGA were 3 cm shorter than the AGA children, and weighed 2 kg less, while the children born LGA were taller by 3 cm and heavier by 2 kg.3 The SGA group was still about 3 cm shorter at age 7 years than the AGA group, while the LGA group was 3 to 4 cm taller; the SGA group was 2 kg lighter, and the LGA group 2 to 3 kg heavier than the AGA group.41
A few large US studies have looked at the entire range of birth weights and demonstrated that growth status based on size at birth tends to track during infancy and early childhood; that is, relative rankings are maintained. Among the more than 10,000 white, singleton infants followed prospectively through age 7 years by the National Collaborative Perinatal Project (1956-1974),8 those infants light for term (<5th percentile for birth weight) weighed 4 kg less at age 7 years compared with those heavy for term (>95th percentile). Infants short for term (<5th percentile for birth length) were shorter by 6 cm at age 7 years than those long for term (>95th percentile).7 In a later study, a similar discrepancy was seen for weight at the extremes for black children in the National Collaborative Perinatal Project.8 The sample of 4689 white, term infants measured at ages 6 to 11 years in cycle 2 of the National Health Examination Survey (1963-1965) for whom birth certificates were obtained also showed a small but consistent positive association between birth weight and child size.10 For each additional kilogram of birth weight, attained weight from ages 6 to 11 years was about 2 to 4 kg higher.
Finally, Binken et al9 looked at the growth through age 5 years for children in Tennessee enrolled in the Special Supplemental Food Program for Women, Infants, and Children from 1975-1984, basing the analysis of growth outcomes on 500-g categories of birth weight without regard to gestation. Outcomes included age-adjusted length and weight (z scores), adjusted using CDC references. They found considerable tracking through age 5 years; and the children in the birth weight strata maintained their relative positions through time, after an initial period in the first 6 months of catch-up for infants weighing less than 2500 g and a slowdown for infants weighing 4000 g or more.
Thus, the findings reported here on an ethnically diverse sample of US-born infants and children confirm those from clinical or national cohort studies, both in the direction of the findings and the magnitude of the effects. However defined, SGA infants remain shorter and lighter in early childhood with smaller head circumferences, and LGA infants remain longer and heavier with larger head circumferences. These findings underscore the need to evaluate the growth of infants and young children relative to their birth weight status, whether they are born preterm or their absolute birth weights fall outside currently accepted limits.
Both birth weight and a reliable estimate of gestation are needed to determine birth weight status. A limitation of these analyses is the necessity of relying on estimates of gestation from the LMP to determine birth weight status when more clinically accurate estimates may be available. However, our use of gestation from the LMP is unlikely to have caused a bias in the findings. Although widely recognized as being prone to error,42-44 gestation estimated from the LMP is still used as the basis for the development of birth weight for gestational age reference percentiles,43 including those used in these analyses.14 Further, most infants in the analyses were born at term (93%), and the probability that a term infant will be correctly classified as such based on the LMP estimate (positive predictive value) is close to 95%.42 Cases born postterm, where the positive predictive value for the LMP estimate is very poor,42 (12%) were excluded from the analyses.
The NCHS/CDC growth charts for the US are currently being revised to include the infant and child growth data collected in the most recent National Health Examination Surveys, including NHANES III.45,46 When these charts become available for general clinical use, there will be opportunity to evaluate growth status based on an infant's weight at birth and, we would suggest, gestation. Although infants born preterm and small (LBW) may be best evaluated using charts specific to such children,11,19 moderately LBW (1500- to 2500-g) infants born at term can be evaluated using the NCHS/CDC charts, recognizing that since they are also likely to be SGA, they may show catch-up but track at the lower percentiles through early childhood. However, of equal import, SGA status is associated with later growth despite the fact that 64% of the infants classified as SGA in this sample were not LBW, and only 10% were born preterm. Infants born SGA, who account for about 9% of all live births, normally have a period of catch-up growth in early infancy (by 3-6 months), but remain deficient in size (hovering around the 25th percentile) through age 47 months. Large for gestational age infants account for about 11% of births, and almost 25% of the infants classified as LGA in this sample weighed less than 4000 g at birth. Nevertheless, these LGA infants slowed down in growth, but remained around the 70th percentile (upper tertile) for size through early childhood. Thus, it seems that for the 20% of US-born infants who are born at the extremes of birth weight, their growth may be best considered in light of their status at birth.
Accepted for publication June 19, 1998.
Corresponding author: Mary D. Overpeck, PhD, Division of Epidemiology, Statistics, and Prevention Research, NICHD/NIH, Building 6100, Room 7B03, Bethesda, MD 20892-7510.
Editor's Note: With the revision of US growth charts almost completed, this study is timely in that it points out the importance of the first point on the chart.—Catherine D. DeAngelis, MD
Hediger ML, Overpeck MD, Maurer KR, Kuczmarski RJ, McGlynn A, Davis WW. Growth of Infants and Young Children Born Small or Large for Gestational Age: Findings From the Third National Health and Nutrition Examination Survey. Arch Pediatr Adolesc Med. 1998;152(12):1225–1231. doi:10.1001/archpedi.152.12.1225
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There Is No Such Thing as a Michelin-Starred Chef
When it comes to famous and successful chefs, there's no higher accomplishment than being awarded a Michelin star. Originally beginning as a rating system by the tire company of the same name in 1904, it was devised to help motorists in France locate places to eat during their cross-country journeys. It has since become a global benchmark, and you'll often see some of the biggest names in food described as a "Michelin-starred chef" or having a certain number of Michelin stars — yet neither of these descriptions are technically true.
Allow me to explain.
Michelin stars — ranging from one to three — are only awarded to restaurants. That means the chef, the kitchen staff, and the restaurant as a whole all share the star(s). Although the head or executive chef usually gets the credit, they cannot take the stars with them after they leave. Alternately, the establishment doesn't lose a star when its head chef leaves either, but the stars also don't transfer if the restaurant opens up a new outlet in a different location.
How can one give a chef credit for their part in earning a Michelin star for a certain restaurant? Simple. Instead of stating, "Michelin-starred chef Daniel Boulud," you can say, "Daniel Boulud, chef of the Michelin-starred restaurant Daniel." Sure, it's a few more words, but it's the most accurate way to actually describe the accolade.
Besides, if you're talking about a food expert, you'll probably want to sound like you know a thing or two about the industry as well.


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Hello, I have applied to the Mechanical Engineering Masters program for Fall 16 at University of Wisconsin Madison. After applying I noticed that I had to secure an advisor, So I emailed 3 POIs (whom I've named in my SOP) that I am interested in their work, neither of them replied but my advisor requirement got checked off (though I don't know who my advisor is). Is that a good thing? does it mean a good chance of getting admitted? Also I did not see an option in the application form to upload my CV or resume, so naturally I did not submit it but my status shows that they have all the materials they need to make a decision. How can they judge a profile without a resume? How am I supposed to let them know about my projects, papers or work experience (kinda the backbone of my application)? Wisconsin Application process for Mechanical Engineering is pretty WEIRDDD!!
Wisconsin-MadisonDoes anybody have any insight into what the culture of the program at Wisconsin is like now that they have switched to smaller cohorts/guaranteed funding? I realize that in the past Wisconsin has been characterized as overly competitive since funding was not guaranteed. If they had not made the change, I would be wary of attending their program. However, since the change was recently instituted in the Fall of 2011, I'm not sure what to expect if I did enroll. Anybody have any insight or ideas about what to expect?


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Cwot View Profile View Posts. Originally posted by JDCS:.
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Raised in Lakewood, NJ, Shoshanna Keats Jaskoll now lives in Israel with her family. She raises awareness of issues that plague the Jewish and world community. Topics she takes on include child sex abuse, women in Judaism, Israel-Arab conflict, and general human stupidity. She is a founding member of Chochmat Nashim, a organization dedicated to positive change in the Jewish community. Professionally, as co founder of REACH3K, she brands and writes for some of Israel's best nonprofits & businesses.
Shoshanna also writes for The Jerusalem Post and blogs for the Times of Israel, The 5%Club and Reach3K.


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The Winter's Tale
Courtyard Theatre, Stratford
THIS epic of a story is gloriously brought to life in the first of the Royal Shakespeare Company's long ensemble performances.
As one of Shakespeare's final plays, the Bard really went to town on the drama.
While the first half is a dark, moving tale of the King of Sicilia's mistaken jealousy of wronged wife Hermione and its horrific results, it lifts into a romantic, joyous comedy with the next generation after the interval.
Director David Farr has slimmed it down, keeping it gripping throughout the two and a quarter hours.
The strong cast is led by the exceptional Greg Hicks as King Leonte.
A must-see. Continues on various dates until October 3.


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Nothing to Do? Bakersfield Has PLENTY Going On This Weekend!
I seriously doubt this is everything, but there is a TON of stuff happening in Bakersfield this weekend!
Friday, 4/20, Truxton Mile will be hitting B Ryders! Get more info HERE!
Saturday 4/21 is Record Store Day! This year, you can expect releases from AWOLNATION, David Bowie, a new single from Florence and the Machine, and stuff from The Cure! You can check out the special releases list for this year HERE!
Local places participating in Record Store Day include World Records and Going Underground! Going Underground will team up with Tiki-Ko for drink specials and World Records will have live music featuring Hate Drugs, Crimson Skye and more! Check out the article from The Bakersfield Californian for more about what local places are doing to celebrate HERE!
Also on Saturday, you've got:
The 7th Annual Relay For Life Benefit Tribute To The Ramones at Riley's Tavern! More info can be found HERE!
Jay Smith Group and Marlon Mackey at Sandrini's at 9! More info HERE!
Something super cool combining music and nerd culture is The Watchtower: Comic Book/Anime Con Hip Hop Concert on Saturday! This is something that is TOTALLY up Ruben from Nerd is the Word's alley! Check out the schedule and info on how to get tickets HERE!
Charity and Community
Friday night at the Icardo Center at CSUB, it's the 24th Annual Battle of the Badges! This yearly event benefits all of the amazing things that Bakersfield Police Activities League gets to do for kids at their after school program. Get more info on the event HERE! And learn more about all of the cool stuff BPAL does HERE!
You can help clean up Bakersfield with the annual Great American Cleanup event! Keep Bakersfield Beautiful and volunteers can help clean up areas of town in honor of Earth Month. Get more info HERE!
On Sunday, 4/22, you have the Kern County Mega Adoption Event at Kern County Fairgrounds. Rescue organizations and shelters from all over Kern County are getting together and helping pets find homes…and you find a new family member. The event will be 10 a.m. to 4 p.m. and you can get more info HERE!
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On Sunday, 4/22, Chabad of Bakersfield is presenting another Pop Up Jewish Deli! You best BELIEVE I am all about those kosher dogs, corn beef sandwiches, and pastrami. So, so, so good! Get more info HERE!
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Caligari at The Empty Space opens this weekend! "Adapted and reinvented from the 1920 silent film The Cabinet of Dr. Caligari, the stage production follows Francis, her quixotic betrothal to the beautiful Jane, the horrifying mystery of Dr. Caligari, and the subsequent murders that precede his path. In his fervor to learn and reveal the nature of the doctor and his somnambulist Cesare, Francis risks her life, her lover—and her mind." Get all the info you need HERE or online at esonline.org
Also continuing theatre-wise:
Picasso at the Lapin Agile at Stars West Comedy Theater! Info can be found HERE!
Godspell at Bakersfield Community Theater! Get your info HERE!
Anything else going on? Lemme know at firstname.lastname@example.com!


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Meanwhile Back At Mama's - Tim McGraw (feat. Faith Hill)
[Verse 1: Tim McGraw]
Runnin round in this new truck
Bank lets me borrow from month to month
I'm runnin out of credit, find a little Cash on the radio
Standin still they're blowin past, numbers on cars goin NASCAR fast
What I wouldn't give for a slow down, don't ya know?
Cause where I come from, only the horses run
When the day is done, we take it easy
[Chorus: Tim McGraw]
Meanwhile back at Mama's
The porch light's on, come on in if you wanna
Supper's on the stove and beer's in the fridge
Red sun sinkin' out low on the ridge
Games on the tube and Daddy smokes cigarettes
Whiskey keeps his whistle wet
Funny the things you thought you'd never miss
In a world gone crazy as this
[Verse 2: Tim McGraw]
Well I found a girl and we don't fit in here
Talk about how hard it is to breathe here
Even with the windows down can't catch a southern breeze here
One of these days gonna pack it up and leave here
[Chorus: Both]
[Bridge: Both]
Oh I miss yeah a little dirt on the road, I miss corn growin in a row
I miss being somebody everybody knows, there everybody knows everybody
I miss those small town routes, walkin around in muddy boots
The sound of rain on an old tin roof
It's time we head on back
[Chorus: Both]
Cause meanwhile back at Mama's
The for sale sign's goin up and I'm gonna
Dump this truck and the little I got
On a loan to own and a three-acre lot
Put supper on the stove and beer in the fridge
Goin' for broke and we're gonna be rich
Watch the sun settin on the ridge
Baby tell me what you think about this
[Outro: Both]
Me and you back at Mama's
Yeah me and you back at Mama's


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Passenger flights return to Carlisle airport after 25 years
Scheduled passenger flights are to return to Carlisle Lake District Airport for the first time in more than 25 years, it has been announced.
Scottish-based Loganair will operate routes to Dublin, Belfast and London Southend from 4 July.
Airport owner Stobart Group had planned to relaunch services in June 2018, but faced problems in recruiting air traffic control staff.
The company said it was "chuffed" to be bringing back commercial flights.
Passenger flights stopped in 1993, although the airport has still been a base for private aircraft and flying schools and is also used by the military.
In 2017 the airport was given £4.75m by Cumbria's Local Enterprise Partnership to upgrade its terminal and runway.
Significant benefits
Kate Willard, from Stobart Group, said: "I would like to thank the people of Carlisle, Cumbria and the Lake District and our partners for their patience.
"Despite the delays we are chuffed that we are bringing commercial flights back to the region for the first time in more than 25 years."
Jonathan Hinkles, managing director of Loganair, said: "These air services will significantly benefit the overall Carlisle and Borderlands region, attracting thousands of tourists and enhancing connectivity for those wishing to do business at both ends of the routes."
Cumbria Tourism managing director Gill Haigh added: "The flights will open up new markets and give potential visitors new alternative transport options to come and explore iconic landscapes and experiences throughout Cumbria."
Tourism contributed £2.9bn to the Cumbrian economy in 2017, with 47 million people visiting the region, according to Cumbria Tourism
Services will operate five days a week, with Loganair using Saab 340 aircraft for the journeys.


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ENGLISH-PART I: Yapress for Dummies
Yapress for dummies
In this post we are interviewing Carlos Sanchez Herrero, founder of Yapress.
We spoke about his project in order to understand it in his essence, the mission, philosophy and how it really works.
Carlos Sanchez-Herrero is a TV producer for TVE ( national state-owned public-service television broadcaster in Spain) in 1982. By this time he was part of the exciting challenge of launching Antena 3 (Antena 3 – Spanish tv channel) .
For more information click here (in spanish):
- What is Yapress?
It's a platform that provides to digital media agencies content made by people (journalist or communicators) from their mobiles in order to be the voice of the street with the possibility of doing it live.
- By Digital media agencies you mean communication agencies, marketing agencies, digital newspapers?
Mixed newspapers, radios and digital tv or even blogs.Actually I think we're in the middle of a deep transformation aimed towards a comprehensive concept of communication, where immediacy and multichannel broadcasts will make the difference in terms of format and credibility and specialized niches.
- Why those agencies would buy videos to Yapress and not to other communication agencies?
I think those are different services, but if a local media had to choose I would say because of price, immediacy, accuracy and independence, and I would add that the main reason is to invest in their future.
- What is the average length of Yapress videos?
We offer three types; one where we offer separate pieces (10-30 seconds) so the agency can tailor edit it, another one (2nd) edited and ready to use (between 1 and 3 min.) , if it's an order it can reach up to 10 minutes and the third one called customizations (5 to 20 sec) consisting of intros and personalized goodbyes .
- About the short videos I saw on the web videos from 1 minute or even 30 seconds, what is the newsworthy interest and why those videos would be purchased by such digital media agencies?
Of the three types mentioned above, this is the most versatile because it can be part of an article, a story or a scoop in itself.
- What is the niche market of Yapress and his specialization?
Our main market are local media, they can buy only what it works for them and this allow them to respond to more news and events.
- You mentioned that it's a platform but then, what differentiates Yapress from other online communications agencies?
Precisely the fact that is a cooperative concept.In this case YAPRESS acts as an agent representing the journalist/communicator and only charges 20% to fulfill the role of a manager who publicizes, advises, coordinates, sells the work and send this economic income directly to your bank account when simultaneously the agency downloads the video from the server.
- Do you consider Yapress also a communication agency, a video producer, news producer ?
We do not produce videos or news, we try to achieve maximum performance in the communication process of third party products. We are a platform that tries to coordinate the work and initiatives of a lot of people who want to tell stories. To sustain this we propose a reliable and transparent compensation.
- Why a newly journalism graduate would choose Yapress as their first work experience rather than other media or communication agency?
We try to integrate them from the beginning with equal opportunities and remuneration and they will learn and work with a great number of experienced professionals. They would also have the possibility to promote their products and be noticed by the best media heads and they will part of an important project that will undoubtedly transform the new journalism ecosystem.
- 3 great differences between Yapress and other large communications/news agencies as "agencia EFE" or Europa Press ?
1.- Percentage of 75 to 80% in sales and auctions
2.- To get paid as soon as the agency downloads the video.
3.- Cooperative approach.
- What does a freelance journalist wins by collaborating with Yapress.?
In addition to get paid, validation in the media if his/her work is worthy it, he/she will learn from other professionals and the opportunity to be promoted, and to coordinate and optimize his work.
- What is yapress business model?
The business model is based on charging small fees for services to media and partners.
- You talk about trying to bring together experience and youth.
On a trip to Germany, I was impressed by the team of three people of different ages in different roles within a large company; the older one was supervising, the middle-aged, one performed the main tasks and the apprentice observed and executed the lighter tasks. In our project it's essential to bring together the enthusiasm of the youth and the savoir faire of the experienced ones.
- Where can I see clearly on the web this differentiation (senior/junior)? Where can I identify that it's about a young or more experience journalist?
Within the platform, we designed a profile verification system for each yaper, with several fields which goes from, f.e, university degree to association or entity partnership .
- What is a Yaper? Is it the same as a collaborator? Which are the values and mission of a Yaper?
Confucius said: » Choose a job you love, and you will never have to work a day in your life."
This project is more than a platform to access media, is a change of paradigm based on a collaborative philosophy called YAP.
YAP is an acronym for the words You Are Press or Yo Ahora Participo ( I now participate).
The mission is to create an ecosystem of collaborative journalism where anyone with the help of Yapress app (mobile) , can work with the media together with a group of journalists, videos and/or interventions in different events and news coverage.
- We often hear that journalism is dead, that many journalists are influenced by political interests, what does Yapress thinks about it?
We believe that journalism is, more and more, directing itself where the money is «J2M vs M2J» (journalism to money versus money to journalism) mainly because journalists have to make ends meet. I like to make an analogy with the lawn, Grassroots Journalism. If a single strand of grass can be blown away by the wind or water this will not happen if heavily rooted .
- You say: «media editors can buy exclusive or shared services".
You mean that digital media agencies should install Yapress mobile app on their mobile? Or / and in their pc's? In addition to the mobile application, is there is a pc application?
It is the same app for both Android and IOS mobile and PC.
To access the 2nd part click here:


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Report Ad
Expired! This ad has expired. aNUgtq5f
$2303 Two bedroom Apartment for rent
- Price$0.00
Austin, Travis
Texas, USA
Sublet.com Listing ID 3332511 East Austin 22 for just 2303 Images are representative of the property, not necessarily the unit. Pricing and availability change daily. Call for the most updated information. 28557 Austin Apartment Specialists
- Posted on: 2017-06-26 07:05:29
- Classified ad views:
Map location: 78702, Austin, Travis, Texas, USA
Contact Seller


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01-03-2017 05:07 PM - edited 01-03-2017 06:33 PM
Someotherguy (Lenovo) stated this morning:
Here's the full story about LSC on Win10. When Win10 1507 launched in July 2015, we had LSC in the Win10 factory preloads. Starting with the preloads that are built on Win10 1607 in July 2016, LSC was removed and the hardware scanning features were moved to Lenovo Companion. My point is, LSC is not intended for Win10 1607 or later. If you are having problems running the Companion hardware scan, let me know and I will try to help debug that. And there are other options for diagnostics as I wrote in a previous post.
In this post: message 9
The way I read it LSC works Windows July 2015. After anniversary update, or later, august 1,2016, LSC is useless. Use Companion diagnostics.
I ASSUME Lenovo does not wish to Upgrade LSC to support Aug 1, 2016 windows, but chooses to Upgrade companion diagnostics to support win 10 august 2016 and later.
Lenovo needs to make a clear statement.
I have windows version 10.0.14393 Build 14393, ...>1607
1507 and 1511 are discussed here:
If you have my release, you are good except for LSC.
Surprised that there have been zero replies!
I share with you the issue that Lenovo needs to make clear statements (or find where they are) about when their preinstalled and branded software reaches the "End of Life" (EOL).
For example IBM lists all it's software on the lifecicle page and gives you the "EOL" date if it applies.
If an EOL date does not apply yet, they just leave the date blank until you get the surprise with an announcement.
For the moment the way that I have to recognize is a Lenovo software reached the EOL is:
1) They put an announcement like this saying you need to uninstall some software that will not run after a Windows 10 update.
2) You don't see that software being released for Windows 10 on the download page.
3) You don't see updates of the software in a long time.
I tried to document Lenovo branded software under the Thinkwiki here: http://www.thinkwiki.org/wiki/Categoryoftware
Remember that those pages are an personal effort that I try to keep updated (help is welcome) . It is not official Lenovo material and not formally supported by Lenovo.
|Martín Itúrbide
OS2World.com NewsMaster
Self-proclaimed Trackpoint Fan Club President
"Don't Panic"
Remember: Your Friend Wil Declares....
|Please click "Kudos" for Ego Boost !!
I think I understood some confusion I got with "Lenovo Solution Center" and Windows 10.
I used to have listed "Lenovo Solution Center" as supported under the Windows 10. But now that I search Lenovo's page about it, it says that LSC is only available for Windows 7 and 8.
Where was my confusion? Lenovo seems to removed the page where it used to said that LSC was available for Windows 10. Here it is the archived page:
So, I'm guessing that "Lenovo Solution Center" is finally getting withdrawn, or was it an accidental change?
I think it can be usefull to have a formal statement from Lenovo about this tool.
|Martín Itúrbide
OS2World.com NewsMaster
Self-proclaimed Trackpoint Fan Club President
"Don't Panic"
Remember: Your Friend Wil Declares....
|Please click "Kudos" for Ego Boost !!


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Girl Develop It (GDI) creates welcoming, supportive opportunities for women and non-binary adults to learn software development skills.Through classes, projects, and events, GDI students develop code, confidence, and community. We envision a world where all people are included and empowered in developing the future of technology. Learn more about Girl Develop It on our website: https://www.girldevelopit.com/Want to lead with GDI? Tell us why here:https://docs.google.com/forms/d/e/1FAIpQLSekQYRAKq26ONeQ77a0LYQbk8znbYFN_0c2ZUj4jcwL6dOwTA/viewformPlease review and commit to our Code of Conduct before joining this group: http://www.girldevelopit.com/codeofconduct
Comfort Zone Cafe
SPoT Coffee
Taichi Bubble Tea
Organic 3 Café


text:
If you have been suffering from back pain, neck pain, headaches, sore muscles, or poor health, don't wait another second to begin your road to recovery! If you've been involved in an auto accident, we're here to help you recover as quickly as possible. We can help you improve your energy and mood, increase the quality of your sleep and help you lose weight. At Innovation Health, our Chiropractic Doctors will assist you towards greater health and wellness – the foundation of you.
To begin living pain free today, call Innovation Health at 704-549-3005 or schedule an appointment online!


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It's never too early for kids to learn programming and building skills! Our Intro to Robotics Club will give kids the opportunity to make simple robots perform complicated tasks in a fun and challenging way. The club will focus on learning to program by using block-based coding languages to get their robots to complete a variety of missions. By the end of the session, our robot enthusiasts will be creating their own challenges.Register Now
Mondays – 4:00 to 5:30 p.m.
Fall Session
September 9, 16, 23, 30
October 7, 13, 21, 28
November 4, 11, 18
December 2, 9, 16
Cost is $400 for the season. Auto Discounts are in place until August 15th.
You can pay in full at registration or make payments.Register Now


text: Welcome to the website of Second Free Mission Baptist Church. We are honored that you have logged on and have given us the opportunity to share with you information about our church. Our desire is to spread the word of God in every way we can to all the people we can. Our prayer is that you will not only be informed about our church, but that you will be inspired and uplifted in your own personal walk with Christ.


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"We were pleasantly surprised with the professionalism of the specialists. The unit was delivered and installed as quoted. The unit is performing as advertised. The install team were neat, clean and did a clean install. They went over all aspects of the sales / install and answered all our questions. We can safely recommend Waychoff's to our friends and business associates. We look forward to many years of continued comfort and service from our Trane and from Waychoff's."
"This a very professional company that came the next day after being contacted late in the day prior. The two guys that came to the door that did the work were well dressed and very courteous. They cleaned my diver vent and it works perfectly. I have their literature and will be calling them when I m ready for duct cleaning. Nice equipment too! Thanks for the good work. Nice not to have scroungy guys showing up at the door. "


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A kayaker helped in Namibia helped save the life of a young dolphin this week.
The dolphin was a juvenile Benguela dolphin, also known as a Heaviside's dolphin. It was scooped up by Naude Dreyer on Paaltjies Beach and deposited back into its natural home. The moment was captured by a companion of Dreyer's. The video currently has over 4.6m views on Facebook.
"On our way back from tour this morning, we came across this juvenile male Benguela Dolphin, still alive on the beach," he told Storyful. "It's not clear how he ended up on there in the first place."
Dreyer said that he was worried that the dolphin might not take to the water but as soon as the dolphin realised there he was he took off like a bullet.
Via Mashable


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Cheap baby clothes prices does not have to mean poor Quality! You will see this noted in checkout.
Personally I would recommend another brand. The best one I've personally tried and it's worked well for me and my friends you can find here: www. buypuregarciniacambogiapillsonline.
com I know they currently have a special offer on and you can get a free bottle, just pay the 4. 99 shipping fee which is an absolute bargain, much better value than this product and a much better quality product.
DHgate helps you get high quality discount newborn baby girl clothes at bulk prices. pimpfilmzcq.cf provides newborn baby girl clothes items from China top selected Clothing Sets, Baby & Kids Clothing, Baby, Kids & Maternity suppliers at wholesale prices with worldwide delivery. Find great deals on eBay for cheap newborn baby clothes. Shop with confidence. Cheap baby clothes prices does not have to mean poor Quality! At Baby Mall Online, we are committed to offering our guests great quality baby clothing with cute artwork and designs at the lowest prices. Baby Mall Online was built on offering parents and caregivers the best baby products while understanding their need to shop on an affordable budget for their newborn baby.


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Five members from both the Garrison Petawawa Men's and Women's Soccer teams were chosen to go to the second annual All for One Cup presented by BMO on Sept. 4 in Toronto. (Above) The men who were chosen include, from left, Corporal Tristen Armitage, Private Spencer Hoerdt, Corporal Anto Dugalic, Private Gabe Jones, and Corporal Promise Okoronkwo. This Canadian Armed Forces Appreciation Soccer Day raised money to benefit work of MLSE Foundation and Holland Bloorview Kids Rehabilitation Hospital. (Submitted photo)
Members of Grn Petawawa soccer teams invited to 'All For One Cup'
By Patricia Leboeuf
Posted on Thursday October 3, 2019
Five members each from the Garrison Petawawa Men's and Women's Soccer teams were invited to Toronto to participate in the second annual All For One Cup presented by BMO.
This Canadian Armed Forces (CAF) Appreciation Day of Soccer event was an opportunity for the athletes to play their favourite sport and mingle with Toronto's top companies and business leaders at the BMO Training Ground. As well as short 15-minute soccer games, the Sept. 4 event featured celebrity appearances, auctions and games for the public, with all the proceeds benefiting the work of MLSE Foundation and Holland Bloorview Kids Rehabilitation Hospital.
1st Battalion, The Royal Canadian Regiment (1 RCR) Corporal (Cpl) Promise Okoronkwo was one of the players chosen to attend; he and his teammates were given this honour as they were the winners of the 2019 CAF Regional Men's Soccer Championships.
He has played soccer his entire life, and when he joined the CAF about five years ago, he just kept on playing but at a higher level.
"One of the great things that I love about playing with the military is that there is no rank structure," said Cpl Okoronkwo. "So often guys that you see in uniform might be officers or senior NCOs, but when you are on the same team together, you are just friends."
He added his Chain of Command has been very supportive of him playing soccer.
"1 RCR is very supportive of guys who play military sports," Cpl Okoronkwo said. "The Commander is a really big advocate of physical training and being in shape."
After winning Regionals, the Petawawa team went to the Nationals where they were unfortunately defeated by Winnipeg in the semi-finals. However it was nonetheless a great opportunity to see the skills of some phenomenal athletes, which Cpl Okoronkwo appreciated.
"It was my first time going to that level and it was a really good experience," he said.
He trains hard to keep up his fitness, working out regularly to ensure his cardio can take 90 minutes of running across the field, and practices with the team about four times a week in the summer and two times a week in the winter. All while balancing his job and his family life, making sure his three kids get to their own soccer practices.
To see his hard work rewarded by All for One Cup was gratifying. Other members of the men's team who went to Toronto included Corporal Tristen Armitage, Private Spencer Hoerdt, Corporal Anto Dugalic and Private Gabe Jones, who said that the All for One Cup was an incredible experience and one they will remember always.
"The guys that are represented in our Garrison sports have huge potential," said Rebecca Olstad, Military Sports Coordinator. "Their background and what they bring to the game, on and off the field is phenomenal."
She is proud to say that they are all burgeoning leaders that are dedicated to both their careers and to their sport. They train both on and off-season, which is not necessarily always the case for all athletes.
"The passion for their sport comes through and to see that displayed is amazing," she added. "When we think of the people that we chose to go to take part in the CAF Appreciation (Day), I think they were very well suited to represent the ability of our Canadian Forces members."


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Author Affiliations
- Paolo Durigutto1,
- Claudia Grossi2,
- Maria Orietta Borghi3,
- Paolo Macor1,
- Francesca Pregnolato2,
- Elena Raschi2,
- Michael P. Myers4,
- Philip G. de Groot5,
- Pier Luigi Meroni2 and
- Francesco Tedesco2,*
- 1 University of Trieste, Trieste, Italy;
- 2 Istituto Auxologico Italiano,IRCCS, Milan, Italy;
- 3 Istituto Auxologico Italiano,IRCCS, Milan, Italy; University of Milan;
- 4 International Centre for Genetic Engineering and Biotechnology, Trieste, Italy;
- 5 University of Utrecht, University Medical Center Utrecht, Utrecht, The Netherlands
- ↵* Corresponding author; email: tedesco{at}units.it
Clinical studies have reported different diagnostic/predictive values of antibodies to domain 1 or 4/5 of β2glycoproteinI in terms of risk of thrombosis and pregnancy complications in patients with antiphospholipid syndrome. To obtain direct evidence for the pathogenic role of anti-domain 1 or anti-domain 4/5 antibodies, we analysed the in vivo pro-coagulant effect of two groups of 5 serum IgG each reacting selectively with domain 1 or domain 5 in LPS-treated rats. Antibody-induced thrombus formation in mesenteric vessels was followed by intravital microscopy and vascular deposition of β2glycoproteinI, human IgG and C3 was analyzed by immunofluorescence. Five serum IgG with undetectable anti-β2glycoproteinI antibodies served as controls. All the anti-domain 1 positive IgG exhibited potent pro-coagulant activity while the anti-domain 5 positive and the negative control IgG failed to promote blood clot and vessels occlusion. A stronger granular deposit of IgG/C3 was found on the mesenteric endothelium of rats treated with anti-domain 1 antibodies, as opposed to a mild linear IgG staining and absence of C3 observed in rats receiving anti-domain 5 antibodies. Purified anti-domain 5 IgG, unlike anti-domain 1 IgG, did not recognize cardiolipin-bound β2glycoprotein I while able to interact with fluid-phase β2glycoproteinI. These findings may explain the failure of anti-domain 5 antibodies to exhibit in vivo thrombogenic effect and the interaction of these antibodies with circulating β2glycoproteinI suggest their potential competitive role with the pro-coagulant activity of anti-domain 1 antibodies. These data aim at better defining really at risk patients for more appropriate treatments to avoid recurrences and disability.
- Received May 22, 2018.
- Accepted November 14, 2018.
- Copyright © 2018, Ferrata Storti Foundation


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Price: $9.94
Quantity: 1 available
Book Condition: Near Fine
15 pages; An informative booklet for the general public about tuberculosis - prevention, symptoms, diagnosis and treatment. Issued the same year as the documentary short "On the Firing Line: The War Against Tuberculosis," also issued that year was a French postage stamp "La Defense contra la Tuberculose." It was not until 1946 with the development of the antibiotic streptomycin that effective treatment and cure became possible. ; Experience the pleasure of reading and appreciating this actual printed item. It has its own physical history that imbues it with a character lacking in ephemeral electronic renderings.
Title: About Tuberculosis
Categories: Medicine and Medical History,
Publisher: Boston, John Hancock Mutual Life: 1936
Binding: Paperback
Book Condition: Near Fine
Size: 16mo 6" - 7" tall
Item: 1.00 Item
Seller ID: 37118
Keywords: Tuberculosis Public Health Initiatives Pamphlet