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A few years ago Bob stopped teaching workshops focussing instead on sharing his knowledge of working with kilnformed glass powders and his signature techniques in a series of e-Books (downloadable PDFs). We have published four e-Books - an introductory book, an intermediate book, a workbook, and a book on firing schedules.
The intermediate book and workbook build on techniques taught in the introductory book - they are not stand-alone. Thus, a person must first purchase and learn the techniques in the introductory book before moving on to the other two books.
The e-Books are available for purchase on this website, through AAE Glass, and through Warm Glass UK.
INTRODUCTION TO KILNFORMED GLASS POWDERS: Basic Crackle Texture, Micro and Backed Wafers
INTERMEDIATE KILNFORMED GLASS POWDERS: Pebble, Oriented, and Colour-Filled-Veins Textures
KILNFORMED GLASS POWDERS WORKBOOK 1: Eight Projects Featuring the Basic Crackle Technique
FIRING SCHEDULES FOR KILNFORMED GLASS: Just Another Day at the Office
For more information, click here.


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I think the best musics from a RPG Maker are the battle musics from VXAce.
I think the best musics from a RPG Maker are the battle musics from VXAce.
@SolonWise True, I thought so too! Which is why I might buy it. They must have patched that glitch by now...
You know, when it goes on sale during the steam sale, it will be pretty cheap (probably less than 20$, perhaps even close to 10$ or less).
The problem is, I will only use the MV version from now on. It would be great if I could buy only the assets from the VX Ace, since I don't need the software anymore.
Buying even the software is pretty cheap. During the steam sale, you should just buy xp, vx, vx ace, mv. Together it's something ridiculous, like less than 40$.
Watch for humble bundle sales on RPGmaker stuff. I picked up VXace, plus a ton of DLC for less than $10.
Thank you all for your advice! And I'm likely getting VX Ace for my birthday in July, according to my mom (I live with her right now)
I'd buy the MV in the last sale. Maybe in the next one I will buy ACE, but I'm from Brazil, and maybe here, it wont not be as cheap as I wish.

subset: commoncrawl


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Jennifer Jason LeighVerified
Photos of Jennifer Jason Leigh
Jennifer was born under the official name Morrow, Jennifer Lee on February 5th, 1962. Known to her close friends as JJL, she has been a credited actor since the 1982 film Fast Times at Ridgemont High.
Jennifer Jason Leigh is a dependable leading actor. She has starred in three films including the 2003 mystery film In the Cut as the character Pauline, the 1996 crime movie Kansas City playing Blondie O'Hara and the 1994 biography release Mrs. Parker and the Vicious Circle cast as Dorothy Parker.
Jennifer has made such a successful career in supporting roles, that it actually surpasses most leading actor's careers. She has appeared in thirteen films including: the 2013 comedy film The Spectacular Now as the character Sara, the 2007 comedy movie Margot at the Wedding playing Pauline and the 2005 drama release The Jacket cast as Dr. Beth Lorenson.
Her most commercially successful project to date has been the 2002 crime film Road to Perdition, which brought in $104,000,000 at the box office.
Jennifer is a cultural icon, having been featured on the cover of at least twenty-seven magazines, captured in more than sixteen pictorials, interviewed in over twenty-seven publications and featured in thirty-eight magazine articles.


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'British women are UGLY and men ONLY care about looks': Founder of new dating site that pairs rich men with beautiful women sparks controversy
- Secret Diamond Club has just launched in UK
- Aims to pair millionaire men with beautiful women
- Men pay up to £100,000 for full membership
- Women are rated 1-100 based entirely on their physical appearance
- The higher a girl's rating, the less she pays for membership
- Founder says British men can't find dates because women here are 'ugly'
'If you don't want to settle for anything less than perfect then the Secret Diamond Club is for you', a sultry voiceover informs prospective customers in a video advertising a new controversial dating website.
The Secret Diamond Club, which started in Demark and has spread across Europe and America has just launched here in the UK to a rather mixed response.
While the club insists it is receiving growing levels of interest in Britain, opponents have branded the club – which pairs rich men with women rated purely on their looks- as an example of chauvinistic objectification.
Scroll down for video
The Secret Diamond Club has spread across Europe and America has just launched here in the UK to a rather mixed response
Women who join up have to meet the strict looks criteria of a panel of twenty 'experts' and submit 3 photographs- including a full body shot- from which they are given a rating out of 100
Started in 2010 in Denmark, the site was started by serial entrepreneur Gus Terkelsen, 33, whose aim was to introduce a new high-end dating concept. He believes the world's richest men often don't have the time to search for love, but nor do they want to lose control of the dating process and be match-made.
And Gus has a rather controversial reason for his decision to launch in the UK, claiming rich British men can't find love as the women here are unattractive. He told MailOnline: 'Coming from a Scandinavian country we know Britain as a country of ugly women.
'There are a lot of a wealthy men here but the women are not very attractive and it is difficult for the men to meet good looking women.
VIDEO Extraordinary dating club caters to some of the world's richest men
Founder, Gus, left says British women are 'unattractive' so men with money can't find suitable dates here
Men are not submitted to any questions when they attempt to join the site, only to provide an email address and informed about pricing
'We already have over 30 millionaires members from Denmark and across Europe and we're now signing up the UK's most eligible and wealthy men.
'These types of men may not have a lot of time on their hands, but they don't want a control freak matchmaker telling them who and where to date. They want to feel free to make the perfect choice themselves.'
Costing up to $100,000 (£60,000) a year for men to join, the site already boasts a raft of millionaire businessmen, from 'European tennis players to self-made millionaire internet entrepreneurs.'
Women can join the site for considerably less, however they do have to meet the strict looks criteria of a panel of twenty 'experts' and submit three photographs- including a full body shot.
Male members can sort women how they wish, as well as filtering women so they only ever see women above a certain rating
Women pay up to £30 a year for one year's membership to the site, depending on the rating they are given by the panel form 1-100 (100 being the best), which is calculated based on their photographs, but adjusted according to their age and the other women at the club they join.
Male members are able to buy memberships for multiple clubs, choosing from a single club ($10,000 or about £6,000 a year), a 'region' such as North America or Europe which gives access to all the clubs in that area ($50,000 or about £30,000 ) or global membership, which at a $100,000 (£60,000), gives a man free reign to look at and contact all the women signed up to any club in the world.
Men can pay for various levels of membership, giving them access to the women in one to all of the clubs across the world
Women however can only sign up for one club. For example women living in France would sign up for the Secret Diamond Club France, and their rating is calculated in comparison to others signed up to that club. So in a club full of stunning women, your rating is likely to be lower.
Women's rating also affects how much they pay for membership; the lower your rating, the more you pay.
Any non-physical factors such as interests or level of education are not taken into account, and men can filter the women they view based on rating, with many opting not be visible to, or view themselves, any women who scored less than 90.
Gus Terkelsen, 33, says that appearance is ultimately the most important thing to men
Gus says he was inspired to start the business because he saw a gap in the online dating market.
'I noticed on another dating website that the men weren't necessarily physically attractive and that those men who were standing in a suit were rated higher.
'I concluded that women weren't interested in looks and were instead interested in other factors- namely financial success.
'Although other sites for millionaire men exist, they only charged £10 a month for membership so what I found is most of the men on there were not in fact rich and were often dubious or weirdos. I figured if a man really has a lot of money, he will be willing to pay.'
Unsurprisingly, this view of the world, where men are purely driven in their romantic endeavours by ascetic factors, and women's affections motivated by money, has been challenged by many.
'The site just mirrors society. It is a truth that men like good looking women, it is very very important to them,' Gus says.
'Ugly girls don't like the site and poor guys don't like it. They don't want to admit that guys prefer beautiful women and women want rich successful men.
'The ugly girls create this moral concept around the idea; attempt to moralise the website. But if you speak to any evolutionary psychologist they will tell you this is the way we evolved as a species.
Gus admits a woman's personality does come into play in romantic pairings, but only once a certain level of beauty had been satisfied.
'It (appearance) is a very very important thing for men. Period.
'It is a lower boundary, and then on top of this you need personality and compatibility. But looks are the first sorting mechanism, especially in internet dating.'
When asked if a man would ever date an ugly girl based on her good personality, Gus's answer was resolute: 'No. No I don't think so.'
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Updated lipid management guidelines include a category of "extreme risk" patients in whom LDL cholesterol should be lowered below 55 mg/dL, according to a summary by the American Association of Clinical Endocrinologists and American College of Endocrinology.
Achieving such a low LDL cholesterol (LDL-C) level is possible with well-established medications such as a combination of simvastatin and ezetimibe and the newer, more clinically powerful agent PCSK9 inhibitors, said by the chair of the guideline committee and professor of clinical medicine, University of Miami, in an interview. The "extreme risk" category was derived largely from IMPROVE-IT and supporting meta-analyses.
The new category applies to patients with established atherosclerotic cardiovascular disease (ASCVD) who have any of the following risk factors.
• Progressive ASCVD including unstable angina after achieving an LDL-C level less than 70 mg/Dl.
• Type 2 diabetes mellitus, chronic kidney disease stage 3 or 4, or heterozygous familial hypercholesterolemia.
• A history of premature ASCVD (before age-55 years in men, 65 years in women).
Heterozygous hypercholesterolemia is more common than many physicians realize, affecting as it does 1 in 250 people.
"Supporting evidence for the 'extreme risk' category with an LDL-C of less than 55 mg/dL was recently announced with the top-line results from the FOURIER CVD outcome trial utilizing PCSK9-inhibitor therapy, which met both its primary and secondary endpoints.
PCSK9 inhibitors are extremely expensive. In my view, payers should not be denying patients who clearly meet the Food and Drug Administration-approved indications for PCSK9 inhibitors and those within the extreme risk criteria. Yet, I have been made aware that 80 percent of insurance claims for PCSK9 inhibitors in these extremely high-risk and vulnerable patients are being denied."
Inclusion in the updated AACE lipid management guidelines should strengthen PCSK9 inhibitors' place among lipid-lowering drugs that are acceptable to insurance companies by making it clear that PCSK9 is appropriate and indicated for select patients.
Aside from creation of the extreme risk category, the AACE lipid guidelines discuss the available tools for making a global risk assessment of having a cardiac, vascular, or stroke event in the next 10 years, without favoring any one risk score.
Among the systems discussed, with links are the Framingham, MESA (Multi-Ethnic Study of Atherosclerosis), Reynolds, and United Kingdom Prospective Diabetes Study risk scores.
The guidelines provide separate approaches to management of people at various ages.
- Latest
- Trending


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Sometimes life just doesn't seem to go to plan. With having to make sure the frosts come on time, Eira already has her hands full, then she goes and adds a neighbour she's in love with, a cocky vampire, and a pesky half-summer fae that just won't leave her alone...
As a descendant of Jack Frost, Eira's only job is to make sure the frost arrives on time. Well not her only job, but her most important one. And when they don't, it's a race against time to get them back. Because if the seasons don't change...well it's best not to go there.
Saving Eira is a RH set in the Paranormal Council Universe and the first book in the Fated Seasons series.
Product Details
|Laura Greenwood
|Publication date:
|Fated Seasons: Winter Series , #1
|Sold by:
|NOOK Book
|Sales rank:
|File size:
About the Author
Laura is a USA Today Bestselling Author of paranormal romance, reverse harem, and contemporary romance. When she's not writing, she can be found drinking ridiculous amounts of tea, trying to resist French Macaroons, and watching the Pitch Perfect trilogy for the hundredth time (at least!)
You can check out Laura's Website here:
Or join her Facebook Group:
For a full book list, please see here:
Customer Reviews
Average Review
Most Helpful Customer Reviews
Imagine being a descendant of Jack Frost and somehow you can't get the frost flowing. Now think about being needing sex to keep your energy levels up. Well this is what Eire has been experiencing. She is frustrated both magically and sexually. Who can she turn to for help? I found this a fun sexy book that deals with love and the magic of the four seasons. It is filled with an assortment of well crafted and interesting paranormal characters. The storyline follows the struggles of Eire as she tries to find love, enough to satisfy her, and who is blocking her magic. There are some very interesting twists and surprises. It is a light hearted paranormal adventure with enough heat and romance blended in. It is the first in a series and I for one am looking forward to reading more of the Fated Seasons series of books. I received a free copy of this book via Booksprout and am voluntarily leaving a review.
I enjoyed this book. The first in a series there was no cliffhanger. Eira is an interesting young woman but I wished we could have had a little more about the men. Maybe as the series progresses that will happen. This is a quick read you won't be sorry you read. I received a free copy of this book and I am voluntarily leaving my honest review.
Emotionally thrilling, action packed and engaging romantic adventure filled with danger, magic and mystery... really enjoyed every heart pounding twist and exciting turn. A great read from beginning to end that was devoured in a few hours.
Eira and Isolde were born 32 minutes apart, and it made all the difference to Eira who was tasked with responsibility for the very important job of the frosts coming on time, which affected other seasons. Actually, twins should not have been born at all because no one knew how the powers of their ancestor, Jack Frost, would show up in the two girls. As it turned out, Eira had all the powers except one -- precognition. Izzy had precognition and a sprinkling of snow magic. The problem is, this year the frost is late! She hadn't felt the tell-tale tingling that signaled it was time to bring on the frosts. Who is responsible for interfering with this process? Ultimately after a night on the town to satisfy needs periodically caused by her succubus blood, she pushed herself out onto the dance floor and Eira finds her three mates after they settle a little skirmish: Josh, a witch and her best friend whom she had been craving for the past several years; Rueben, a vampire; and later, Leth, a half-Fae of the Summer Court who was sitting in her living room when she came out of the shower, who had to hold back from Eira information concerning what is going on with her powers. So Leth made a date with her, Rueben got her phone number to call her up later, and Josh was finally ready to admit how he had felt about her for years and was now ready to act on! The question now is, can her men help her get her power back so that she can do what needs to be done about the frost? I enjoyed this story, especially having read another in the series and feeling more comfortable with it. I loved the strong character we see in Eira. Her guys were likewise interesting, with Josh being my favorite of the three. Mixing humor into the story makes it easy to read and enjoy. Grab your copy and see if Eira gets her powers back in time!
Finding The Problem Is Half The Solution In Itself, Which She's Realizing! Tis the SEASON... Her TIME to make things a bit NIPPY, But... When She REACHES for Her COLD, Her FROST isn't doing what IT. IS. TOLD! Seems IT has been Blocked... But NOT by I.C.E! Which woulda been NICE, Cuz to Fix Her Blockage it's gonna take... Her to TAKE some MATES! I rarely give Coveted 5 STAR ratings; they're saved for Books/Items that Outshine, Outclass, & Outperform their competition... They've gotta give me something MORE! Laura Greenwood does just THAT In Her WORK. Each book's World Building is Exquisite & Unique... Not to Mention the RoMANce & Drama; She's TRULY Won Distinction as a 5 STAR Author for Her Catalogue of Work, Especially for "Saving Eira;" Kudos Ms. Greenwood for ALL your Stellar work!!!!! I was granted, via B00|{$P®0UT, an ARC of Laura Greenwood's "Saving Eira (Fated Seasons: Winter Book 1)." I highly recommend this book to others based upon its own merits. All opinions expressed within this review are uniquely my own & freely given! Until next time... Happy Reading!
I thought this was a cute read. I enjoyed the interactions between Eira and her mates. Though I was thinking the end would be a bit different since I already read a book that must come later in the series. I'll have to read through everything in order and find out where everything goes wrong in the world. I received a free copy of this book via Booksprout and am voluntarily leaving a review.
Eira is a descendent of Jack Frost and her only job is to make sure the frost arrives on time but this year it's late. Everything changes for Eira when she realizes her power is blocked. Rueben, Leth and Josh are Eira's fated mates and are working together to find a way to get her power back. Great writing, interesting characters, a steamy reverse harem and a great start to the Fated Seasons series.
I am loving that Laura Greenwood is getting a lot of her books done on audio, makes me fall in love with these characters all over again ❤! I thought Marina was perfect for Eira and did a good job with the guy voices (sometimes it was hard to understand what she was saying, I think that was mostly when she was playing Rueben. I thought her inflections and sarcasm/snark was on point haha. Also the guys personalities really shown through with Marina's performance. For the story, I cannot wait for more in this series. I absolutely love the guys (especially Josh). I was definitely channeling Eira when she was ready to jump Rueben haha. I also liked the complications with Leth and hope to see him stand up for Eira now that everything is out in the open. I am intrigued to see what happens with these Eira and Aledwen and the other Queens/Princesses. I was surprised the frost thing was sorta resolved already but still want to find out more. Here's to hoping these characters start super talking to Laura so we can get more of these amazing stories (she has to go with which characters are the loudest since she has so many amazing stories and characters going on at one in her head haha). Amazing job Laura and Marina, great combo for Saving Eira
Saving Eira by Laura Greenwood is a wonderful new start to a brand new series. I am so in love with this new series, it is fast paced and funny and in some places it is a steamy read. I loved reading this story and I highly recommend this story and if you buy it you will not be disappointed. I received a free copy of this book via Booksprout and am voluntarily leaving a review.


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How To Purchase Google Stock
Have you ever been able where the only factor you'll be able to work out to give somebody as a present was cash? And the way all the pieces should be valued is through a mystical legitimizing course of that is central to the cult of money: Mammon's invisible hand" makes itself obvious inside the free market," which is Mammon's digital temple. Stursberg brought a enterprise method to the CBC, which in apply translated into turning it into a non-public community backed with public funds. These financial instruments collectively are collectively known as the money supply of an financial system. That is one thing that individuals will usually procrastinate once they're low on money. We lastly bought up some supplies on the boxing day sales akin to a brand new tree, xmas lights, window decorations, and tree ornaments. Our Twitter followers and frequent guests to cbcExposed assist us to continue to show CBC's abuse and waste of tax money as well as their ongoing left wing news bias.
Most homeless folks don't out survive a yr outdoors or they might develop into mentally ailing from the exposure. It's time to say no, to say 'you're hard earned tax money is … Read MoreRead More →


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To achieve the rising demands of varied industries, we have started a different channel devoted to the western region of the country. A big team of coordinators and service engineers are readily available to your purchase and service calls. We can visit your site to guide you how our products can help you in enhancing the excellence of products by conducting various tests.Our range of equipment is designed for different industry verticals like PET, Packaging, Automotive, Textiles, Polymers, Colour testing, etc. With the high industrial growth in the region, there is a sharp rise in the demand for testing instruments in West Delhi.
Establishing a testing lab has become major investment and fair asset if you want to make your project a success. To fulfil the demands of testing instruments in West Delhi we have established a full-fledged zonal team that looks after all the customers in the region. We make sure we swing into action very rapidly to make your manufacturing line work non-stop. The quality of the product is the major factor behind the success and failure of a brand. No matter how much promotion you've done, if your product does not meet the quality standard it would fail to make a mark in the market.


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8 Great Modern Retro Hairstyles Stock – It truly is the simply just layout that suits each and every facial area model.They may well be directly that maximum hairstyles may function out for them. Some of the highest desired Modern Retro Hairstyles for medium tresses are bangs, easy, curly, bob and directly cuts.
17 best ideas about 1940s Hairstyles on Pinterest for Modern Retro Hairstyles
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A Day in the Life of e Girl Vintage Hairstyles in a of Modern Retro Hairstyles
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Hi, I'm trying to find clocks that automatically reset themselves to the correct time periodically. Before you answer, let me clarify:
- I am refering to real, physical clocks, not the clocks inside PCs, DVD players etc.
- In many countries (especially Europe) the government broadcast a radio signal that allows clocks (that have the proper equipment built-in) to automatically reset themselves. This is of particular value when the time changes to/from Standard to Daylight Saving. See http://mindprod.com/bgloss/radiosynchedclock.html for some examples of these clocks.
However, (a) many other countries do not broadcast this signal, and (b) it's probably not necessary to do so nowadays, since a properly enabled clock could just synch via wireless home LAN to get to a time server.
I've found this one ( http://www.primexwireless.com/data/spec ... ns/AMP.pdf ) but it's over-the-top for my needs. Anyone know of something a bit simpler?
One other, slightly more extreme, idea would be to find a way to simulate the Radio signal. E.g. Build a transmitter that picks up the accurate time from a PC and then transmit that in a small range.
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Auto synchronising real clocks (e.g not PC clocks)
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Thanks, but that's just another example of the technology (albeit a good example) that I'm trying to reproduce. To elaborate, there are two technologies in play, and I guess I'm trying to blend them:durain wrote:how about a casio wave ceptor?
Method #1:
Special radio signal -> broadcast to -> Specially enabled clocks (or watches!)
Method #2:
Computer based Time servers (NIST etc.) -> broadcast thru networks to -> pretty much any client computer
Pros and Cons:
Method #1 is solid, reliable, a bit old fashioned, works only with special clocks and only works in Europe, USA and one or two other places.
Method #2 is solid, reliable, up to date, works only with computers, works worldwide.
What I want is to get Clocks synching with computer-based time servers, such as NIST. This means either (a) Get a clock than connects to a computer network and is enabled to make "what time is it" requests to the time server, or (b) Get an interface from a computer network that can re-broadacst the special radio signal that the Clocks can understand.
I suspect this topic is a little beyond the normal SingaporeExpats discussions, but hey, there's lots of smart, well-connected people reading this, so maybe someone will know something.
- Asian_Geekette
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You may want to look at the link below about radio referenced NTP server.
But I believe you want something which is a bit different than the one above. Like get the timing from the NTP server and create a radio signal?[/url]
But I believe you want something which is a bit different than the one above. Like get the timing from the NTP server and create a radio signal?[/url]
My business is not to remake myself, but make the absolute best out of what God made. -Robert Browning
- Asian_Geekette
- Reporter
- Posts: 558
- Joined: Wed, 10 Jan 2007 4:07 pm
- Location: Still based in Singapore but wanders around...
NTP / Radio referenced clocks
Asian_geekette thanks, that's certainly interesting. But, what I'm after is the other way round, e.g. generating the radio signal given a reliable time source (NTP).
I'll try emailing to some of the people in the sites you've pointed me to.
Thanks again.
I'll try emailing to some of the people in the sites you've pointed me to.
Thanks again.
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The Toronto Maple Leafs and general manager Kyle Dubas have a tough summer ahead of them and it just got tougher.
Aside from the whole Mitch Marner situation, the Leafs have big problems on their blueline.
Jake Gardiner is likely gone through free agency and Travis Dermott just had shoulder surgery so he won't be around for the first part of the season.
The team doesn't have much cap space to find a solution and now one of their top four defenseman has just requested a trade.
According to NHL Insider Bob McKenzie, defenseman Nikita Zaitsev has requested a trade out of Toronto.
Zaitsev has been playing big minutes under Mike Babcock and became Jake Muzzin's partner down the stretch.
What makes the situation even worse is the Leafs have no cap space to take on another contract and Zaitsev is owed $4.5million a season for the next five years, the Leafs probably won't get any significant return.
McKenzie also adds that the Leafs don't believe top defensive prospects Timothy Liljegren and Rasmus Sandin are ready for the NHL yet.
It was Nikita Zaitsev who, for personal reasons, asked TOR today to try to facilitate a trade. He has five years remaining on a contract with an AAV of $4.5M. TOR will try to oblige Zaitsev but are not in a salary cap position to retain much, if any, salary.
— Bob McKenzie (@TSNBobMcKenzie) May 30, 2019


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You'd be wise to assume that my house is swimming in desserts. I've always got a few laying around. So, every now and then, I go on a mission to give away all the desserts. And before I make a new dessert, I often find a victim to give it away to before the oven is even preheated. It keeps me accountable. It also keeps the calories in check.
I find my victim and commit to them via the almighty and ever-binding text message that I will deliver a dessert to their house by 5pm. But sometimes, I mess up. Sometimes I taste-test something and then discover that I don't want to give it away. It's so good. Too good. That's how I felt with my honey shortbread. I stole one cookie out of the batch for taste-testing, and it wasn't enough. I was blown away by their deep, toasty flavor that reminded me of graham crackers. But, I made a commitment. I (reluctantly) passed them off.
I haven't stopped thinking about them. I wanted another batch. I needed another batch. But I also wanted to give you a variation on the recipe so you can make and enjoy both. I halved the recipe to make 12 shortbread bites. And then I did what every human being is doing right now, and filled my grocery cart with strawberries because Spring is finally here!
So, what we're working with here is a shortbread cookie, a dollop of whipped cream, a few bites of strawberry and a gratuitous sprinkling of lemon zest on top.
Don't give these away. Not even one.
Strawberry Shortbread Bites
For the cookies:
For the topping:


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Cohabitation Before Marriage - The Pros Vs The Cons
Nowadays, cohabitation before marriage is often an option that many couples consider. Most couples choose it for convenience, while others do it as sort of a trial run before actually getting married.
There are varying views and sentiments about cohabitation before marriage. But the decision is still for you to make. People can only give an opinion, and not a fact from concrete experience if they themselves have not gone through cohabitation before marriage.
Whether or not living together before marriage is a good idea or not has been the subject of many debates as well. If you're facing this dilemma, the best way to find out is to dig into the pros and cons of cohabitation before marriage for you to arrive at a decision.
So, what are the pros and cons of cohabitation?
Cohabitation Before Marriage – The Pros
Lets examine some of the advantages of cohabitation before marriage:
You will know what you're getting into: This is the best thing about living together before marriage. It serves as a test for marital compatibility. The true nature of your partner will be revealed. "Being with the person" almost all of the time is still not the same as "living with the person". The realities of living together will be made known as it gives a preview of what type of marital life you can expect with your partner.
You'll get accustomed to your partner's habits: You or your partner may have habits that you're not comfortable with or may even find irritating once you live together. Cohabitation before marriage allows each of you to get used to these habits.
You'll develop a routine and personal space: When you do things everyday, it becomes a normal part of your routine. You'll know the where, when, and how's in your house that both of you agreed. The adjustment period during the first few months of marriage won't be as difficult as it otherwise would be.
You'll solve a lot of practical problems: Living together means shared costs. For example, you can save on rent and transportation costs.
Cohabitation Before Marriage – The Cons
After knowing the pros of cohabitation before marriage, it is equally important to consider the cons:
You lose the whole excitement of "being married": If you live together prior to marriage, the tendency is that you will not appreciate the feeling of being married anymore once you do. Everything is almost the same when you are married so there is nothing new to look forward to.
You might suffer criticisms of immorality: Some people consider it a sin to be living together before marriage. You may hear negative feedbacks, especially from religious people and the conservative.
You might just be playing house: Some couples just cohabit without a clear intent of eventually getting married. They do it for convenience and then break up when they get tired of the relationship.
It may put off the wedding indefinitely: This is the major disadvantage of cohabitation before marriage. "Why get married when everything's in place already? It's only the paper that's missing." Or "Why get married when it's not working at all? It's pointless to still get married." Sadly, several researches have shown that only about 1 out of 2 cohabiting couples ever get married.
In the end, it is still your personal choice whether to choose cohabitation before marriage or not. As long as you are happy and have carefully considered the risks involved with doing or not doing it, you will not regret your decision.
Need more information?
Yes, does premarital counseling actually work?
How can I increase my chances of getting a "yes" when I propose?
How can I make a relationship last after the initial spark has gone?


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I'll Stand By You
Paperback(Mass Market Paperback)
"Sharon Sala is a consummate storyteller. Her skills shine in her Blessings, Georgia series. If you can stop reading then you're a better woman than me." DEBBIE MACOMBER, #1 New York Times Bestselling Author
Welcome to Blessings, Georgia, the best small town in the South!
No one is alone as long as there is love to give
Dori Grant is no stranger to hardship. As a young single mother in the gossip-fueled town of Blessings, Georgia, she's weathered the storm of small-town disapproval most of her life. But when Dori loses everything within the span of an evening, she realizes she has no choice but to turn to her neighbors.
Everyone says the Pine boys are no good, but Johnny Pine has been proving the gossips wrong ever since his mother died and he took over raising his brothers. His heart goes out to the young mother and child abandoned by the good people of Blessings. Maybe he can be the one to change all that...
Blessings, Georgia Series:
You and Only You (Book 1)
I'll Stand by You (Book 2)
Saving Jake (Book 3)
A Piece of My Heart (Book 4)
The Color of Love (Book 5)
Come Back to Me (Book 6)
Forever My Hero (Book 7)
A Rainbow Above Us (Book 8)
Praise for I'll Stand By You:
"An amazing story by a true storyteller...Sala once again shows why she is a master of the romance genre." RT Book Reviews, 4 ½ stars
"Small-town romance with humor and heart and a heaping pinch of reality." The Romance Dish
"A heartfelt and emotional love story...incredibly uplifting and gratifying." Book Reviews and More by Kathy
Product Details
|Publication date:
|Blessings, Georgia Series , #2
|Sales rank:
|Product dimensions:
|4.10(w) x 6.90(h) x 1.10(d)
About the Author
Sharon Sala is a long-time member of RWA, as well as a member of OKRWA. She has 115 books and novellas in print, published in six different genres Romance, Young Adult, Western, Fiction, and Women's Fiction and Non-Fiction. First published in 1991, she's an eight-time RITA finalist, winner of the Janet Dailey Award, five-time Career Achievement winner from RT Magazine, five time winner of the National Reader's Choice Award, and five time winner of the Colorado Romance Writer's Award of Excellence, winner of the Heart of Excellence Award, as well as winner of the Booksellers Best Award. In 2011 she was named RWA's recipient of the Nora Roberts Lifetime Achievement Award. In 2017 Romance Writers of America presented her with the Centennial Award for recognition of her 100th published novel. Her books are New York Times, USA Today, and Publishers Weekly best-sellers. Writing changed her life, her world, and her fate. For book list, go to her website: www.sharonsala.net
Customer Reviews
Average Review
Most Helpful Customer Reviews
I simply LOVED this book. Sala shows us that family isn't always blood. And sometimes, we just have to do what's right - not what's easy. This is a story of two families coming together quite non-traditionally, but finding love and home and family regardless. Bullying is bad - no matter where you're from and doing what is right - is, well, right, no matter where you're from. I sure want to sit down and have a glass of tea with Dori and Johnny and the boys!!
This is one of the best feel good books I have ever read. The kind of book you can reread a dozen times and never get tired of it.
One of Sala ' s better efforts and part of the Blessings, GA series. Dori and Johnny are delightful.
Great stories in Blessings, Ga.
Love my werewolves, vampires and alphas, human or other- wise. But sometimes a good, well told simple romance can't be beat. Great story, warm wonderful characters and well written. Read! READ!!
Could not put this book down! Strong, caring, wonderful main characters. Sweet love story. Wish there was an epilogue to read about their new lifestyle and how the boys lived on the other side of the train tracks. Great story!!!
Tears giggles and full on belly laughs - Fantastic book !
A well-written 250 page book of a teenage mother in Blessings, Georgia, and a young man from 'the wrong side of the tracks' raising his little brothers in poverty, and how their lives intertwine in a smalltown atmosphere with heartbreak, humor, and love.
Good read. Looking forward to reading more from this author
One of the best book, I've read this year! I can't wait to read more of this series!
This was a great read....can't wait for the next one..
While technically a New Adult age ranged novel, the maturity level of the principal characters place this solidly in Contemporary Romance. Dori is 17 years old and when she got pregnant, tried out homeschooling, but then just got her GED so that she could start taking college courses. Her son, Luther Joe, is about 6 months old. Dori was raised by her grandparents after her parents died when she was about 8. Since her grandmother passed away, it has just been her and her grandfather, and now Luther Joe. Johnny Pine is 20 years old and raising his much younger brothers, Marshall age 10 and Brooks age 7. Their father is serving a life sentence in prison and their mother died a couple years prior of a drug overdose. Johnny fought to keep his brothers with him, even if it means literally living on the wrong side of the tracks. Since then, it has been a struggle, one day he dreams of a better life for him and his brothers. Dori and Johnny have had a passing knowledge of each other, but neither has had the time or inclination to even think about a relationship with everything else going on in their lives. That is, until everything changes in the blink of an eye one night and Dori's whole world comes crashing down. Johnny and his brothers are the only ones who offer her a hand and she accepts. I think I spent much of the first half of this book either in tears or near tears. It was just scene after scene of heart rending circumstances. But, one thing is sure, you get to know the real Johnny and Dori. The actual romance is very short, most of it happens in about 7 days. But they are very intense days, where Johnny and Dori get to know the true essence of the other person. And you just can't help but cheer them on, after all they have each been through. Though this book doesn't say that it is part of a series, but Ruby from The Curl Up and Dye by Sharon Sala takes part in helping both Johnny and Dori at different time as well as has several scenes told from her viewpoint. I enjoyed this book, though I did think the ending was a bit far fetched, it was in the realm of possibilities. I gave this book 4 stars.
I have been reading Sharon Sala for years and really enjoy her writing! I just loved the characters in this book and cannot wait for the next one.
Great story--one that makes you feel good inside. Looking forward to the next one in the series.
This was one of the best books that I have read in a long time. I can't wait for more in this series
Johnny and dori were so young. I like it when hero and heroine are young in stories. 23 - 27 is good age for heroine. In this story hiwever johnny 20 years old and more of a real man than some older men! I love u johnny. They both had pain in their lives and yet trust was there for each other from the start. Sharon sala's heros are so manly and yet so tender even though they have had oppositions in their lives. Yet it didnt take the caring nature away. Dori was sweet natured as well yet strong;not selfish or witchy. However it didnt tell why johnnys dad was in prison for life. Love this book!!!!!
Got the book based upon the brief description before reading the reviews, unfortunately. If you are thinking this is a marture novel, it is not. Seventeen year olds will not cut it in the quality of writing either. Do not buy this book unless you are a teenager. It is childish in its writing, babylike. A terrible read.
I'll Stand by You by Sharon Sala is a wonderful story that takes place in a small town in Georgia. This is a sweet romance, but it is really story driven about two young people having a hard time in their lives due to terrible circumstances. Dori Grant is our heroine, and I thought she was great. Dori, who is only 18, is a single mother who lives with her grandfather and baby boy. She works as a dishwasher in the local restaurant to help pay the bills. Though Dori lives on the nice side of the town, she is looked at with disapproval from her uppity neighbors. Johnny Pine is our hero, who takes care of his younger brothers, since their mother died. He has a steady job for a contractor, but ends are hard to meet, and he lives on the bad side of town. The story more or less begins when Johnny is called to rescue his youngest brother, Beep, who was beaten up by a small gang of children at school. The town of Blessings stands by Johnny, as he puts in a complaint to the school, and the parents of the children. Beep suffered serious injuries, but will recover. Almost at the same time, Dori suffers a major setback, as her house is on fire. When it is over, the house is destroyed and her grandfather is dead. Dori's uppity neighbors offer her sympathy, but leave her and her boy standing alone, with nowhere to go. It is Johnny who drives by the fire with his brothers, who will come to the rescue to help Dori. What follows is a story of a town split apart by prejudice and one person, in particular who thinks nothing of destroying lives. But there were some really nice people that helped both Dori and Johnny fight the stigma, and the town joins hands to help them. While that is going on, Dori, who is now staying in Johnny's house, takes care of the boys, cleans, and cooks. But Dori's life will change for the better, as the local lawyer who helps her pro-bono, will discover some surprises for her. As each day passes, Johnny and his two young brothers find themselves caring for Dori and her son. Just when you think that things will get better for them, they get thrown another bombshell. The nasty neighbor, afraid of backlash will create more havoc with false lies, causing more trouble for both Johnny and Dori. There is another villain, who will get his just due, some with humor With the lawyer's advice, Johnny and Dori will commit to each other to protect their family from social services in order to protect the children, and a sweet romance truly begins. This was a different type of story that I thoroughly enjoyed. The two main characters, Johnny and Dori were great. It was nice to see some really nice secondary characters that brought the town together to help those in need. Very nice writing by Sharon Sala, and a wonderful uplifting story.


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Inflammation has long been recognized as important in the pathogenesis of acne; however, until recently it was considered a secondary event. Studies over the past decade have demonstrated a central role for inflammation in the development of acne lesions and have opened new opportunities for therapeutic intervention.1 ,2 ,3 Understanding the role of inflammation in the development of acne vulgaris is important for dermatologists, as it may impact our treatment choices and identify additional targets for new treatment modalities. This review will provide a brief overview of some of the scientific literature regarding inflammation in acne. It will also review some recent auto-inflammatory acne syndromes that support the role of inflammation in acne pathogenesis, as well as discuss treatments currently available and in development with anti-inflammatory properties.
Acne vulgaris is associated with excess sebum production, colonization of the follicular infundibula with Propionibacterium acnes (P. acnes), hyperkeratinization, and production of inflammatory mediators. The microcomedone, which arises secondary to ductal keratinocyte proliferation with occlusion of the infundibulum and subsequent retention of sebum, has been postulated to be the primary lesion in acne. Some studies of normal skin in acne-prone patients and early acne lesions suggest that inflammation may precede microcomedone formation and may serve as a trigger for the hyperkeratinization that leads to follicular occlusion.
Jeremy, et al. performed immunohistochemistry on biopsies of clinically normal follicles from uninvolved skin in patients with and without acne and demonstrated cellular, vascular, and proliferative markers of inflammation prior to microcomedone formation.4 In these studies, skin biopsies demonstrated an increase in perifollicular and papillary dermal CD3+, CD4+ T cells, the proinflammatory cytokine IL-1, and the vascular markers VCAM and E-selectin. IL-1ß stimulates keratinocyte proliferation, which may lead to plugging of the follicular ostia and microcomedone formation. VCAM and E-selectin expression are important ligands for tethering and migration of inflammatory cells from the circulation to the dermis and are important in regulating lymphocyte trafficking in the skin.
Thiboutot and colleagues analyzed skin biopsies taken from inflammatory papules and normal skin of patients with inflammatory acne and demonstrated marked up-regulation of genes involved in inflammation and matrix repair in the inflammatory papules.5 By gene array expression profiling, the greatest increases were in: matrix metalloproteases (MMP) 1 and 3; the cytokine IL-8; and the anti-microbial peptides (AMP) human ß-defensin 4 (hBD) and granzyme B. Quantitative PCR and immunohistochemistry confirmed increased expression of mRNA and proteins respectively for the identified genes, confirming increased protein expression. While both of the AMPs hBD 4 and granzyme B demonstrate activity against P. acnes and suppress P. acnesstimulated cytokine release, hBD has pro-inflammatory properties. This up-regulated AMP has chemotactic effects, induces proinflammatory chemokines and cytokines, and stimulates keratinocyte migration and proliferation.6 Il-8 is a proinflammatory cytokine associated with polymorphonuclear leukocyte (PMN) recruitment that also stimulates keratinocyte proliferation. MMPs are involved in normal tissue repair and are highly upregulated in many inflammatory states, including acne. As MMPs selectively cleave collagen, the increase in MMPs in acne is believed to be a factor in acne scarring.
Kang, et al. identified activation of transcription factors nuclear factor -kB (NF- kB), and activator protein-1 (AP-1) and their down-stream target gene products, the proinflammatory cytokines (TNFa, IL-1ß, IL-8, and IL-10) and MMPs, in skin biopsies from patients with acne vulgaris.7 NF- kB is upregulated after T cell activation and translocated to the nucleus, which leads to proinflammatory cytokine transcription. The transcription factor AP1 induces transcription of mRNA for MMPs, particularly MMP1, 3, and 9 which have specificity for dermal collagens. These authors demonstrated collagen degradation in the dermis in skin biopsies from subjects with acne, consistent with the increase in MMPs.8
There is a complex interrelationship between P. acnes, sebaceous lipogenesis, and inflammation.9 P. acnes, a Gram positive anaerobe that resides in the follicular infundibulum, enhances sebaceous lipogenesis, ensuring a lipid rich environment in which the bacteria can flourish. Squalene, a major component of sebum, can be oxidized in the presence of UV light or the oxidative environment associated with inflammation. Peroxidated squalene has been demonstrated to induce production of inflammatory mediators in cultured keratinocytes.10 These inflammatory mediators induce keratinocyte proliferation, which may contribute to follicular occlusion and enhanced sebum retention. Other proinflammatory lipid by-products (ararchidonic acid [AA], prostaglandin E2 [PGE2]), and enzymes that produce inflammatory mediators (lipase, 5-lipoxygenase [5-LOX], cyclo-oxygenase-2 [COX-2]) are also increased in sebum and the sebaceous gland in patients with acne vulgaris. These lipid by-products and inflammatory mediators metabolized from AA help to perpetuate the inflammatory cascade in acne.
In addition to influencing sebum production, P. acnes has a direct role in inflammation, inducing production of several proinflammatory signals, via a Toll-like receptor (TLR2) regulated pathway. Toll-like receptors are a class of surface markers that selectively bind microbial pathogens and activate the transcription factor NF- kB. In acne, TLR-2 is expressed on keratinocytes and monocytes in the perifollicular macrophages of inflammatory acne.11 P. acnes binding of TLR-2 leads to increased production of IL-12 and IL-8. In summary, the tightly regulated cascade of inflammation, hyperkeratinization, P. acnes proliferation, and sebum production appear to be closely intertwined.
Several rare auto-inflammatory diseases include acne as a clinical manifestation and serve as a model for the role of inflammation in the pathogenesis of this disease. PAPA syndrome, a rare autosomal dominant disease, includes the triad of pyogenic sterile arthritis, pyoderma gangrenosum (PG), and acne and shares features with the aseptic abscesses syndrome. PAPA syndrome is due to a defect in PSTPIP1, which encodes proline-serine- threonine- phosphatase interactive protein 1 gene. PSTPIP1 binds to pyrin, the protein linked to familial Mediterranean fever. PSTPIP and pyrin regulate the NLRP3 inflammasome and caspase-1 mediated signaling pathway inflammation. Braun-Falco, et al. have identified a related syndrome with PG, acne, and suppurative hidradenitis (PASH) that shares some components of the follicular occlusion triad.12 A similar aseptic abscess condition, SAPHO Syndrome, has predominately bone manifestations with Synovitis, Acne, Pustulosis, Hyperostosis, and Osteitis as key clinical features.13 While the treatment of these aseptic abscess syndromes remains challenging, some patients with PAPA, PASH, and SAPHO have demonstrated a clinical response to anti-inflammatory agents, such as methotrexate, leflunomide, or drugs that target TNF or IL-1ß (anakinra), underscoring the critical role of inflammation in these conditions. Further characterization of the aberrant proteins, receptors, and signaling molecules involved in the pathogenesis of these inflammatory syndromes is likely to further our understanding of the role of inflammation in acne vulgaris.14
Several agents commonly prescribed to treat acne vulgaris have known effects on one or more components of the inflammatory pathways reviewed above. While the exact mechanism of action for some of our therapeutic armamentaria remains unknown, studies in vitro and in vivo have identified anti-inflammatory activity of retinoids, dapsone, antibiotics and other treatments prescribed by dermatologists to control the signs and symptoms of acne vulgaris. Several drugs in development have demonstrated antiinflammatory activity in vitro, and novel anti-inflammatory mechanisms are being explored for additional development opportunities.
Retinoids are traditionally viewed as keratolytics, promoting keratinocyte differentiation and turn-over to prevent follicular occlusion. Modlin and co-workers demonstrated that all-trans retinoic acid down-regulates TLR2 expression and function as well as the TLR2 co-receptor CD14.15 In vitro studies have also demonstrated retinoid inhibition of arachidonic acid induced ear swelling in mice and inhibition of peritoneal macrophage lipoxygenase activity.2
Antibiotics, used both topically and systemically in the treatment of acne, have both anti-microbial and anti-inflammatory properties. In addition to direct anti-microbial activity targeting P. acnes, clindamycin has multiple activities on macrophages and leukocytes including: inhibiting cytokine release from bacterially stimulated macrophages, modulating the stimulated production of reactive oxygen species by macrophages, and potentiating the activity of phagocytic leukocytes.16 ,17 Clindamycin has also been shown to decrease lipase production, thereby decreasing proinflammatory free fatty acids in the sebum. Clindamycin and tetracyclines inhibit the release of neutrophil chemotactic factor from neutrophils exposed to P. acnes and production of IL-1ß. Inhibition of neutrophil chemotactic factor decreases inflammatory cell migration into early acne lesions, while a decrease in IL-1 ß would decrease keratinocyte proliferation and hyperkeratinization.
Dapsone is administered systemically to treat a wide range of inflammatory dermatologic diseases and is particularly prescribed in conditions characterized by a PMN predominant infiltrate such dermatitis herpetiformis, bullous systemic lupus erythematosus, and Sweet's syndrome. Sweet's syndrome, which is also known as acute febrile neutrophilic dermatosis, shares some features with the auto-inflammatory family of disorders described above. Topical dapsone gel has been approved for the treatment of acne vulgaris. In vitro, a wide range of anti-inflammatory affects have been associated with dapsone including inhibition of: IL-8 release from cultured keratinocytes; leukocyte migration via inhibition of integrins; signal transduction after G-protein activation; calcium-dependent neutrophil function; release of prostaglandins, leukotrienes, and lysosomal acid hyrolases; and formation of 5 lipoxygenase metabolites.18 In a randomized study of tazarotene cream alone or in combination with dapsone gel, the addition of topical dapsone resulted in greater efficacy than monotherapy, suggesting that the addition of an anti-inflammatory agent to a retinoid-based regimen provided clinical benefit to patients with acne.19
Dermatologists have also used anti-inflammatory agents not approved for the treatment of acne vulgaris in select circumstances to help control acne when our usual treatment options have been unsuccessful. Examples of such treatments include the addition of dapsone, methylprednisolone, and non-steroidal anti-inflammatory agents (NSAIDs) to treatment regimens.20 In a four-arm, randomized study in 60 subjects with acne vulgaris, concomitant administration of oral ibuprofen and tetracycline was more effective than either agent alone.21
Another agent with reported anti-inflammatory activity is zinc, which has been used both topically and orally to treat acne vulgaris.22 A combination erythromycin-zinc topical solution is approved for treatment of acne vulgaris in Europe and other ex-US countries.
There are several novel agents in development for acne vulgaris that target inflammation as a major component of their mechanism of action. Agents in early development with a mechanism of action that targets the inflammatory pathway include: Topical epigallocatechin-3-gallate (EGCG), a major polyphenol in green tea; NVN1000, a nitric oxide-releasing compound; and gevokizumab, a systemically administered monoclonal antibody that targets IL-1ß.
Multiple lines of evidence support a pivotal role for inflammation in the pathogenesis of acne vulgaris. Many currently available acne treatments have demonstrated anti-inflammatory activity, although it is difficult to separate the anti-inflammatory effects from other actions of these agents. A greater understanding of the inflammatory pathways relevant in acne may identify targets for additional treatment options.
Dr. Rico is a dermatologist and Chief Medical Officer at Novan Therapeutics.
- Stein Gold LF, What's new in acne and inflammation, J Drugs Dermatol. 2013; 12(6):s67-s69.
- Weiss JS, Messages from molecules: deciphering the code, J Drugs Dermatol. 2013; 12(6):s70-s72.
- Bellew S, Thiboutot D, Del Rosso JQ, Pathogenesis of acne vulgaris: what's new, what's interesting and what may be clinically relevant, J Drugs Dermatol. 2011;10 (6):582-585.
- Jeremy AHT, Holland DB, Roberts SG, Thomson KF, Cunliffe WJ. Inflammatory events are involved in acne lesion Initiation, J Invest Dermatol. 2003;121:20-27.
- Trivedi NR, Gilliland KL, Zhao W, Liu W, Thiboutot D. Gene Array Expression Profiling in Acne Lesions Reveals Marked Upregulation of Genes Involved in Inflammation and Matrix Remodeling, J Invest Dermatol. 2006; 126:1071-1079.
- Harder J, Tsuruta D, Murakami M, Kurokawa I. What is the role of antimicrobial peptides (AMP) in acne vulgaris? Experimental Dermatology 2013; 22:386-391.
- Kang S, Cho S, Ho J, Hammerberg C, Fisher GJ, Voorhees JJ. Inflammation and Extracellular Matrix Degradation Mediated by Activated Transcription Factors Nuclear Factor-κB and Activator Protein-1 in Inflammatory Acne Lesions in Vivo. Am J Pathol. 2005;166:1691-1699.
- Kang S, Cho S, Ho J, Hammerberg C, Fisher GJ, Voorhees JJ. Inflammation and Extracellular Matrix Degradation Mediated by Activated Transcription Factors Nuclear Factor-κB and Activator Protein-1 in Inflammatory Acne Lesions in Vivo. Am J Pathol. 2005;166:1691-1699.
- Zouboulis C. Propionibacterium acnes and Sebaceous Lipogenesis: A Love-Hate Relationship? J Invest Dermatol. 2009; 129:2093-2096.
- Ottaviani M, Alestas T, Flori E, Mastorfrancesco A, Zouboulis CC, Picardo M. Peroxidated squalene induces the production of inflammatory mediators in HaCaT keratinocytes: a possible role in acne vulgaris? J Invest Dermatol. 2006; 126: 2430-2437.
- Kim J, Ochoa MT, Krutzik SR, Takeuchi O, Uematsu S, Legaspi AJ, Brighbill HD, Holand D, Cunliffe WJ, Akira S, Sieling PA, Godowski PJ, Modin RL. Activation of toll-like receptor 2 in acne triggers inflammatory cytokine responses. J Immunol. 2002; 169 (3): 1535-41.
- 12. Braun-Falco M, Kovnerystyy O., Lohse P, Ruzicka T, Pyoderma gangrenosum, acne, and suppurative hidradenitis (PASH)—a new auto inflammatory syndrome distinct from PAPA syndrome, J Am Acad Dermatol. 2012; 66: 409-15.
- Nguyen MT, Borchers A, Selmi C, Naguwa SM, Cheema G, Gershwin ME. The SAPHO syndrome. Semin Arthis Rheum 2012; 42 (3): 254-65.
- Chen W, Obermayer-Pietsch B, Hong JB, Melnik BC, Yamasaki O, Dessinioti C, Ju Q, Liakou Al, Al-Khuzaei S, Katsambas A, Ring J, Xouboulis CC, Acne-associated syndromes: models for better understanding of acne pathogenesis, J Eur Acad Dermatol Venereol. 2011; 25: 637-646.
- Liu PT, Krutzik SR, Kim J, Modlin RL. Cutting edge: all-trans retinoic acid down-regulates TLR2 expression and function. J Immunol 2005; 174 (5): 2467-70.
- Lyte P, Sur R, Nigam A, Southall MD. Heat killed Propionibacterium acnes is capable of inducing inflammatory responses in skin. Exp Derm 2009; 18: 1070-1072.
- Del Ross JQ, Schmidt NF. A review of the anti-inflammatory properties of clindamycin in the treatment of acne vulgaris. Cutis. 2010; 85: 15-24.
- Kircik L. Harnessing the anti-inflammatory effects of topical dapsone for management of acne. J Drugs Dermatol. 2010; 9(6): 667-671.
- Tanghetti E, Dhawan S, Green L, Ling M, Downie J, Germain MA, Kasteler JS, Kireik L, Oefelein MG, Clinical evidence for the role of a topical anti-inflammatory agent in comedonal acne: findings from a randomized study of dapsone gel 5% in combination with tazarotene cream 0.1% in patients with acne vulgaris. J Drugs Dermatol. 2011; 10 (7): 783-792.
- Kaminsky A. Less common methods to treat acne. Dermatology. 2003; 206(1): 68-73.
- Wong RC, Kang S, Heezen JL, Voorhees JJ, Ellis CN. Oral ibuprofen and tetracycline for the treatment of acne vulgaris. J Am Acad Dermatol. 1984; 11 (6); 1076-81.
- Brandt S. J Drugs Dermatol. 2013; 12(5): 542-545.


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Is James Chester on borrowed time at Aston Villa if Dean Smith signs yet another centre-back?
According to The Daily Mail, Aston Villa want to sign Brentford centre-back Ezri Konsa. This is a player who manager Dean Smith knows very well after previously signing him for Brentford.
Aston Villa could pay as much as £12 million for the big defender and it seems like Smith is sparing no expense on solidifying his back four.
If £12 million is spent on Konsa, Smith will have paid over £40 million on centre-backs this summer following moves for Kortney Hause and Tyrone Mings.
This is great news for Aston Villa fans because it suggests they're very serious about staying in the Premier League, but it's not so good for James Chester and you have to wonder that if the rumour about Konsa is true, is he finished in the West Midlands?
Chester, who cost £8 million in 2016 [Birmingham Mail], had his fair share of injury woes last season and Smith signing three centre-backs doesn't exactly indicate that the Villans boss is expecting to see him a lot this time around.
He's a very good defender on his day, but Chester is also 30 and it might just be the beginning of the end for him at Villa if Konsa is added to the squad.
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"To live with change, to optimize change, you need principles that don't change." -- Dr. Stephen R. CoveySuccess that endures -- sustainable and balanced success -- can seem difficult to achieve in today's turbulent, complex world of change. But those who achieve this kind of success live by seven universal, timeless, self-evident principles that apply in any situation, in any culture.
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The birth of a new channel – Pure Ibiza Radio
09 May2
The birth of a new channel of communication is always good news, especially when those at the helm wield as much in the way of experience and reputation. A team of professionals whose chief goal in life is to spread energy, emotion and feeling through the best sound on the island. Ibiza, the island that they love and live on, epicentre of electronica, mecca of music.
PURE IBIZA RADIO launches in April 2017- a brand new radio station, a project put together by one of the island's most important radio hosts, producer & DJ, David Moreno. 25 years in the game, broadcasting his Ibiza Dance radio programme on different island stations over the years. Few have dedicated so much time, effort, energy, illusion and passion to dance music as Moreno, preserving the spirit of Ibiza at all times.
And now, accompanied by a great team, David is about to embark on what may well be the most important project of his life. Ibiza 2017 is already shaping up to be a year of change and further evolution and this season promises to be one of the most interesting in recent years when it comes to the quality and variety of events and artists that make up the summer programme. With announcements already starting to trickle out of the clubs, PURE IBIZA RADIO has its ear to the ground to bring the listener a taste of what's happening and where, transmitting the news, views and latest trends on the scene in Ibiza through its 97.2 FM frequency.
Lots of new and interesting developments are happening already for the 2017 season, as we get our hands on the line-ups for the clubs across the island. PRIVILEGE-and all that's set to happen in there (much of which is still to be revealed)- is certainly worth a mention, with Juan Arenas in charge and dates already confirmed from Carl Cox who'll be bringing the likes of Cassy, Darren Emerson, Eats Everything, Joseph Capriati, Kerri Chandler, Nastia, Nicole Moudaber, The Martinez Brothers and tini amongst others, along with him. Heavyweights John Digweed & Sasha have taken up residency for Tuesdays at the world's biggest club and expectations are high for the return of these two to the island.
HÏ IBIZA, the converted beach club in Playa d'en Bossa, has already announced Martin Garrix as its resident for Monday nights, Eric Prydz on Tuesdays bringing guests including Kölsch, Pig & Dan , Catz N Dogz, Agoria, Tube & Berger, Mathew Dear, Dusky or Cristoph, among others; Armin Van Buuren premieres his residency on Wednesdays, Fridays are Glitterbox and Black Coffee takes on the Saturday slot. The Opening Party has been confirmed for May 28 th with a great line up including Black Coffee, Luciano, Apollonia, Andrea Oliva B2B Davide Squillace, Bas Ibellini, Djebali, Joris Voorn , Kölsch, Matthias Tanzmann, Nic Fanciulli, Bedouin and Anna Tur.
PACHA, under new ownership, hasn't much to report in the way of many changes to its summer programming except the new residency of Hot Since 82 with Labyrinth, replacing Insane on Friday nights. Flower Power, Solomun, Maceo Plex, David Guetta, Martin Solveig and Bob Sinclar all look set to keep doing their thing at the club and all have already announced their opening dates.
AMNESIA has confirmed it will throw open its doors for the summer on Saturday, May 27th with a line-up that includes Eric Morillo, Cuartero B2B Mar-T, Gorgon City, Hannah Wants, Jack Master and Patrick Topping among others. Elrow has claimed the Saturday nights, kicking off on June 3 rd . Mondays are all about Cocoon, with Adam Beyer confirmed for seven dates along the way. Together and Cream will take on Tuesdays and Thursdays respectively, both geared towards an altogether more British audience and Musicon with Marco Carola is set for Fridays. We await further news on what to expect on Tuesdays and Sundays.
DC10 has marked 22 nd May as the date it throws its doors open, with Seth Troxler, Jamie Jones, The Martinez Brothers, Kerri Chandler, Jackmaster, Davide Squillace, Matthias Tanzmann, Damian Lazarus, Marcel Dettmann, Tania Vulcano, Ellen Allien, The Black Madonna, Dan Ghenacia, Dyed Soundroom, Shonky, Dubfire, Adriatique,DJ Tennis, Cirillo, Dvsi, Petar Dundov, Clive Henry, Konstantin, William Djoko, Sossa, Acid Mondays and René all getting involved with that one. Meanwhile, Disclosure have announced their residency for Fridays at the club, under the name of 'Wild Life'. We imagine that Jamie Jones' Paradise will also continue taking charge of Wednesday nights although this has not been confirmed as yet.
USHUAÏA IBIZA will open on Saturday May 27th with an exceptional lineup that includes Pau Kalkbrenner presenting "Back to the Future", Andrea Oliva, Davide Squillace B2B Martin Buttrich, Eats Everything, Francisco Allendes, Raul Rodriguez, Steve Lawler and Uner. They have also already confirmed ANTS for Saturdays and Martin Garrix every Tuesday.
HEART will open with Sven Väth, Acid Pauli and Guy Laliberté on May 26th and the club has also just announced the residence of Bedouin, continuing with its policy of quality downtempo sounds.
SANKEYS has also announced the opening party of Unusual Suspects on May 11th with tini, Janina, Rick Maia, Eats Everything, Frank Storm and Federico Grazzini as well as The Redlight party every Monday from June 19th.
EDEN has confirmed its Opening for May 24th and its summer programme will include Magna Carta on Thursdays and Pukka Up's Tropical Wonderland on Saturdays. Added to that, after its sojourn last summer, Defected- an Ibiza staple over the last fifteen years- are back on the island and taking over Eden's Sunday nights.
And that's just for starters. More parties, more artists and more surprises still to be revealed but so far, it's shaping up to be a very special summer. Stay tuned to PURE IBIZA RADIO for all the latest news, info and soundtrack to the season. It's all here, it's all happening and we plan to be in the thick of it! Stay Tuned!