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Norm SharpPartner / Sales Manager
0418 935 980 Email Agent
View my residential listings View my residential sold listings View my rural listings View my rural sold listings View my commercial listings View my commercial sold listings
Cute 2 bedroom home in the popular Sylvester Street and priced to sell! Why rent, when you could be paying a low mortgage on this cute home. This home has great street appeal and could easily be turned into something special with some TLC. Cozy 2 Bedroom home 1 Bathroom with shower Separate lounge Combined kitchen/dining 1012Sqm corner block 12x6m powered shed Council rates $2,626.50 approx Contact Norm Sharp for more information on 0418 935 980
Price: $79,000
This 4 Bedrooms, 2 bathroom home is the one to see! Neat and tidy throughout with two good sized living areas. Features new vinyl used throughout living areas. The home has a good sized yard waiting to be utilized and enjoyed plus a pool for those hot summer days. Situated approx. 10 minute drive to Hannan's Boulevard and Hannan's Primary School and North Kalgoorlie Primary School. Brick and tile family home 4 Bedrooms 2 bathrooms Front formal living area Open plan family area New vinyl throughout Master bedroom with new carpet Walk in robe to master bedroom Below ground pool Paved patio area Approx 818sqm block Single carport at front Council rates $2547.75/yr Water rates $220.00/yr For your private inspection, contact Norm Sharp on 0418 935 980
Price: $349,000
This delightful 3 bedroom home is the ideal property for someone starting out or the retiree looking to down size but still have the bonus of a big yard and pool. Open plan living area with kitchen looking out onto a great paved patio area which features a pizza oven. Great days/nights of entertaining will be experienced here especially with the below ground pool to cool down in. Brick/veneer and tile 3 Bedrooms 1 Bathroom Open plan living Gabled patio area Powered garage with 2 roller doors Approx 1012sqm block Rear lane access Council rates $1976.34/yr Water rates $220.00/yr For your inspection, please contact Norm Sharp on 0418 935 980
Price: Offers From $290,000
Dont be fooled by the size. This property shouts comfort! Ideal for someone looking to just unpack and enjoy. Very modern kitchen and bathrooms. Big block with loads of potential for a HUGE shed to be built or pool, even better there is room for both. 3 Bedrooms 2 Bathrooms Modern kitchen/ dining area Family area with floor boards Laundry with bench and cupboards Study Patio area Rear lane access 1088sqm block Zoned R20 Close to Cinema, Harvey Norman and secondary schools Council Rates: $1682.88/yr Water Rates: $220.00/yr Contact Norm Sharp on 0418 935 980 for more information
Price: $260,000
If you are looking for a low maintenance, modern 3 bedroom, 2 bathroom home in Central Kalgoorlie with a 9m x 6m shed, look no further! This home is Truly Amazing; it has 3 good sized bedrooms throughout, separate lounge, modern kitchen with stainless steel appliances, dining and family room, new bathroom, laundry, 9m x rear patio, connected to natural gas. 3 Bedrooms 2 New bathrooms Modern kitchen Tiled family/dining & kitchen Separate front lounge Retic lawns 9m x 6m rear workshop with power Split system air-conditioning Natural gas Rear games room Zoned R60/ commercial 506sqm block Council rates $2014.90/yr Water rates $220.00/yr For your private inspection contact Norm Sharp on 0418 935 980
Price: $379,000
This brick and tile home is perfect for the first home owner or someone looking to down size! Brick and tile featuring 3 bedrooms, 1 bathroom and open plan living area. Convenience of a double carport, nice paved patio area and a shed. 3 Bedrooms 1 Bathroom Master bedroom has built in wardrobe Brand new carpets through out Open plan living area Well equipped kitchen Gas cooking Gas heating Evaporative air conditioning Paved patio area Shed with roller door Double carport 706sqm block Great location, close to North Kalgoorlie Primary School and Hannans Boulevard Council rates $1803.61/yr Water rates $220.00/yr Contact Norm Sharp on 0418 935 980 for your inspection today!
Price: OFFERS FROM $230,000
Priced to sell, this neat and tidy home would make the perfect starter or investment property! Weather board and iron home 3 Bedrooms with built in robes 1 Bathroom Spacious lounge area Electric hot water Gas heating Leased until the 13th of July 2018 at $250.00 per week Nice patio area Garden shed Under cover parking 890sqm block Council rates $1655.30/yr Water rates $220.00/yr Contact Norm Sharp on 0418 935 980 for your inspection today
Price: $130,000
What a great family home!!! Featuring 4 bedrooms, 2 bathrooms, 2 living areas, good sized yard and powered shed. Located close to Hannans Primary School and Hannans Boulevard. The large sunken lounge area features vaulted ceilings creating the sense of more space and making this area even more pleasant is the natural light that streams through the front windows. The kitchen is very functional with loads of cupboards , dishwasher and is open to the family area. The master bedroom is inviting and warm, features a good size walk in robe and ensuite. Bedrooms 2, 3 & 4 all have built in robes for convenience. Sit back and relax in the patio area and watch the kids run around and enjoy the yard. The powered shed will please the handy man of the house Brick and tile family home 4 bedrooms 2 bathrooms Master with walk in robe Built in robes to bed 2, 3 & 4 Large sunken lounge with vaulted ceilings Formal dining area off lounge Open plan kitchen/ family area 4 Good storage/linen cupboards Gas hot water system Dishwasher Ducted reverse cycle air conditioning Good size patio area Single carport Another open car space at front 7x5m approx. powered shed 832sqm block Council rates $ 2384.65/yr Water rates $220.00/yr For an inspection contact Norm Sharp on 0418 935 980
Price: $385,000
AUCTION- SATURDAY 14TH APRIL AT 11.00AM-ON SITE UNIQUE HOME ON APPROX 5,024SQM BLOCK WITH STABLES! From the glamorous front foyer to the gabled patio area this home is a sure WINNER. This home shouts comfort and lifestyle with the size inside and out. The family home boasts four good sized bedrooms, large ensuite and main bathroom, front formal living, open plan living area and huge games room which overlooks paved gabled patio area and the back yard. The approx. 5,023sqm block is neatly designed and ready to be utilized with four horse stables and working yards completing the area. 4 Bedrooms, 2 Bathrooms Master bedroom has walk in robe Double vanity in the large ensuite Front formal lounge area Open plan living area Kitchen with stainless steel appliances and walk in pantry Huge tiled games room overlooking back yard Lots of storage throughout Great sized laundry Gabled patio area Double lockup garage Garden Shed Horse stables Working yards Approx 5,024sqm block Council rates approx. $2886.46/yr Water rates approx. $220.00/yr For your private inspection, contact Norm Sharp on 0418 935 980
This unit would be the perfect investment property! leased until 6th of July 2018 and receiving $1,347.02 PCM Great time to build your portfolio. This fantastic large unit is deceiving! The unit is situated in a secure complex and is one to see. With the unique interior design and the size, you will be amazed! -Brick and Iron Villa -3 Bedrooms -1 Bathroom -Modern and stylish bathroom -Freshly painted throughout -Brand new carpets throughout -Electric hot water system -Evaporative air-conditioning -Garden shed -Single carport -228sqm Lot Leased until 6/7/18 at $1,347.02 PCM Strata fees $407.52 per qtr Reserve fee $48.28 per qtr Council rates $1527.15pa Water rates $220.00pa To inspect please contact Norm Sharp on 0418 935 980
Price: $210,000
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Feelings, emotions, perceptions… sometimes they are so overwhelming. I know what I want, I just don't know how to get there. I know that God has a plan for me and if I ask Him for what I want, he will give it to me, but the question becomes is it what He wants for my life? I know that God gives us the desires of our heart, but are the desires of my heart in line with what He wants for me, or am I allowing my feelings, emotions and perceptions to take the lead? I am such a complicated person that sometimes I don't even understand myself.
In response to an assignment that I have to do for class, my best friend stated that I "micromanage" my feelings. She is so right, so if I micromanage my feelings, how do I stop doing so? I control my feelings so much that I don't naturally feel. I turn them on and off based on my surroundings and how I want to appear to feel at the moment and sometimes I don't know if my feelings are real or made up.
Somehow, I need to find a way to release some of that control so that I can feel in the way that others feel. I would like to feel a genuine feeling at the right moment instead of a waive of feelings because I can't control them any longer in that moment. I realized this weekend that I live on a roller coaster. I am super high in my happiness and everything is awesome even when it is not, but eventually that high becomes an emotional crash and I find myself distant and in deep need of silence and alone time. I am not depressed and I am not sad. I am not really anything except emotionless and it stinks. I don't enjoy it. I feel myself slipping into an emotional coma and I can't do anything at all about it. I just have to ride it out. With all of the emotional control that I portray on the outside, I think that it would overwhelm someone to really know the emotional disaster that is going on inside. I really do feel so much when all is quiet and when I am left to myself. Maybe that is why I need the "me" time. When I get "me" time, I have the opportunity to bask in the quiet of my house. There isn't a TV or vocal kids. There is not another person who needs me or who I need to think about. It is just me and my thoughts. My thoughts provide me the freedom to work through the emotions that I will not allow another soul to experience. Those moments are precious to me and help me to reestablish a sense of calm.
I want to learn to allow God to lead my path instead of me feeling like I need to control so much. I want to learn to stop and ask for His guidance instead of trying to navigate life myself. There is an awesome calm in knowing that I have Jesus behind me! He is in my corner cheering me on and offering me the road map to life. I just need to push through and tune out all of the noise and let Him lead. He can see the future. He knows what my future can look like. Jesus truly wants nothing but the best for his children, and I am His child…a princess in His eyes. I so badly want to surrender my life completely to Him. I try, but I just take it back time and time again like I actually know what is best for me. It is a little disappointing that after all of this time and after Jesus has shown his love for me on so many different occasions and pulled me out of some dark moments that I am still holding onto parts of my life. At some point I need to give it up.
Learning these things about myself is fascinating. It gives me the opportunity to improve and to grow. It gives me insight into what I need to do differently and what I can work on to be the best for someone else. I have no doubt that I am ready, but I know I could be an even better person for someone. I deserve a whole person and whomever my someone is deserves a whole person as well and I am not about to sit here idle. I am going to fight to be the best me that I can possibly be. I am going to be the woman that Jesus intended me to be. However long it takes.

subset: commoncrawl


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Slip on a headset and let one of three handsome dating simulator stars slip a ring on your finger.
romance games
Seiji attempts to apply the romantic logic of dating simulators to the real world.
Debut work by teen creators smashes crowdfunding goal in less than two hours, aims to be better than made-by-adults titles.
Clever idea makes you the hero of a dating simulator.
Palette Parade's parade of handsome anime versions of art world icons continues to grow.
Japanese lingerie maker aims provide players with sweet, possibly spicy dreams.
Boyish da Vinci and van Gogh have special relationships with friends Michelangelo and Gauguin.
Virtual idol Hatsune Miku takes time out from her busy schedule to sit down for some sweets in augmented reality event.
There's a fine line between "cute displeased" and "hurt-the-player's-feelings" displeased.
Will new technology let them really experience the scent of virtual girls?
Developers warn players of potential emotional trauma while fans praise dating simulator's realism.
Finally, a dating sim for people who are attracted only to inanimate objects!
The expansion of the modern mobile game market has been a boon for romance games. The genre usually doesn't require particularly powerful hardware specs, and the larger profit margins that come with purely digital distribution mean that even niche titles in what's already a niche segment of video gaming can make money for their developers, all of which lets creators keep on creating and players keep on playing the virtual field of dating partners.
But there are two sides to every coin, and if the success of mobile romance games is the shiny penny's unblemished face, what about its bitter, jaded backside? That's now taken care of too, with a new game that gives players the power to make lovey dovey lovers explode, plus meet with a host of other unexpected tragedies.


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Regal Oaks CLC 2B House, Pool Kitchen Parking ROR2
Set in an area of natural lakes and forest designed with space and comfort in mind. the perfect choice after a full-on day in the theme parks or out and about discovering the central Florida region. O…
Getting out and about during your Florida vacation is as simple as it gets! the resort is just 1.4 miles from Interstate 4, the main connecting highway that cuts diagonally through the Orlando area, a…
Place(URL HIDDEN) Miles (approx)
Old Tow(URL HIDDEN) 0.4
I am a professional person, very responsible and serious about my work. I manage multiple properties since nine years ago and as result of my and my team's work we have many returning customers.
Before, during and after your stay, you will have 3 contacts available to you to answer any request or requirements that you may have.


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With a hand-painted pattern inspired by woven textiles, this apothecary jar is beautifully crafted of lustrous white lacquer.


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Esta edición ISBN ya no está disponible.Ver todas las copias de esta edición ISBN.
Book by Garrett Reginald H Grisham Charles M
"Sinopsis" puede pertenecer a otra edición de este libro.
"I see that in the new edition the chapter on enzyme mechanisms has been moved to precede enzyme regulation. This will be a welcome change." "The strength of Garrett and Grisham is that it serves a real introductory role and is very accessible. The graphics are usually very clear and useful." "In terms of the pedagogical features, I like the use of the Essential Question(s) and Outline Questions at the beginning of each chapter as they focus the students and provides a study guide of learning objectives." "Adding new (end-of-chapter) questions is a great idea. Having more questions that integrate material from previous chapters is fantastic. In general, I have liked many of the questions in Garrett and Grisham and assigns me for my students to complete and turn into me for credit." "The authors have done an excellent job of explaining the structural features of the molecules from simplest to most complex, and then have referred to these structural features in explaining functional details." "I like the illustrations in this book very much and the standard format in which they are constructed (certain symbols mean the same thing in every figure.) Because they are substantially more sophisticated than the illustrations in the new edition of Stryer, they are one more reason I have chose to change the Garrett and Grisham for my general biochemistry course in the fall."Reseña del editor:
While illustrating the principles that govern the structure, function, and interactions of biological molecules, this textbook describes the molecular components of cells, the catalytic power of enzymes, the metabolic pathways that orchestrate the synthetic and degradative chemistry of life, and the
"Sobre este título" puede pertenecer a otra edición de este libro.
Descripción Brooks Cole, 2004. Hardcover. Condición: New. Never used!. Nº de ref. del artículo: P110534490336
Descripción Brooks Cole. Hardcover. Condición: New. 0534490336 New Condition. Nº de ref. del artículo: NEW7.3018376
Descripción Brooks Cole, 2004. Hardcover. Condición: New. 3. Nº de ref. del artículo: DADAX0534490336
Descripción Brooks Cole, 2004. Condición: New. book. Nº de ref. del artículo: M0534490336


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Before starting this blog I had no idea on what went on in this corner of the internet world. Now I'm hosting events, doing sponsored post and headed to blog conferences. Who would have thunk it! Just like doing anything you love, you have to keep learning. To learn more in this blogosphere world you may need to attend a conference or two. Every conference is different so before you go you have to sit down and think of why you are going. It could be to attend workshops, meet online friend in person, network with brands, attend parties, meet like minded people or to just get a few days away from the kids! All of these are very good reasons to go. Since BlogHer was in my hometown of Chicago that was more than enough reason for me to go. I'm also a very social person and I love the opportunity to meet new people.
Check out all of Trina's tips on how to make it on "The List" on her blog, Baby Shopaholic!


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It's MLK Day and as I write this post about my first coaching session with Shaun King, Founder of 100 Life Goals University, I am reminded of a quote by Dr. Martin Luther King.
If you can't fly, then run. If you can't run, then walk. If you can't walk then crawl, but whatever you do you have to keep moving forward.
That is very much in the spirit of Shaun King and the community that makes up 100 Life Goals University.
As the call began, I was anxious due to my desire to impress Shaun and seem like a worthwhile client. Even when you are paying for coaching, when such a worthwhile person gives you their time, you want to make the most of it.
Shaun was so approachable that I quickly relaxed and starting sharing what I considered to be my quick-win goals for 2014. These are the list of things that do not require significant resources of time, energy or money but simply decisive action and follow-through. They include:
Obtaining my project management certification: This is a moderate cost but will require commitment to study over three months.
Deciding on grad school: Shaun wisely suggested that once my future plans become clearer, so will the concentration I should choose for my graduate degree. The good thing to note is that 40 is not too late. I have already reached out to my alma mater confirmed that the cost would be approximately $65K, not including the 20% discount provided to all alumns.
Starting a business: Last year, I started hosting networking diners to bring people together, share ideas, find employment and generate opportunities. I know there are organizations out there which provide similar services. I need to decide if my initiative will become a business or remain a hobby — one that I very much enjoy.
Formalizing my blog: This mostly involves deciding on a domain name. "Sherry Clayton Works" was a temporary solution since my name domain was already taken. I will also create a plan for my blog this year.
Beginning to observe others in my desired career: Over the next several months, I will be working to define several goals (even some dreams). One career related goal is to become a full-time writer. Shaun recommended that I follow Jeff Goins. He shared his story with us during the 100 Life Goals Kick-off on New Year's Day. I just downloaded a couple of his eBooks: The Writer's Manifesto and Wrecked for the Ordinary: A Manifesto for Misfits.
What are your goals for 2014?
For our mutual enjoyment, here's a pep talk from Kid President.
Categories: Personal Development, Professional Development


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Question about Samsung Washing Machines
Posted by cliff mathia on
If you can hear it running even with door open its probably in a fault mode as this the only circumstance in which it will run with the door open, what you are hearing is the drain pump and its doing that because there is a leak in the base of the machine setting off its flood switch, if you pull the dishwasher out and lean it back you will see water run out the bottom, then you need to find where its leaking from
Posted on Feb 10, 2017
SOURCE: I have freestanding Series 8 dishwasher. Lately during the filling cycle water hammer is occurring. How can this be resolved
Hi there,
Save hours of searching online or wasting money on unnecessary repairs by talking to a 6YA Expert who can help you resolve this issue over the phone in a minute or two.
Best thing about this new service is that you are never placed on hold and get to talk to real repairmen in the US.
Here's a link to this great service
Good luck!
Posted on Jan 02, 2017
SOURCE: Kenmore HE3T washer leaking water
The rubber seal is called the "bellow". Replacements can be ordered on line at searspartsdirect.com, appliancepartspros.com, or repairclinic.com. All three sites offer great service, so shop around for the best prices.
For instructions on how to replace the bellow yourself, follow this link:
This is not a difficult repair, but it can be a bit intimidating to a beginner. If you have questions along the way, or require additional assistance, please let me know before you rate the solution. I hope this helps you.
Posted on Jan 31, 2009
SOURCE: Door won't open on Samsung washer
This has happened to me twice. Both times I found the drain pump seized up with
1st time) The right rim from a pair of reading glasses
2nd time) A plastic toothpick
Both times the object was in the discharge port of the pump. You can see this by lifting the check valve with the pump removed. Removing the pump is simple. Unplug the washer. You have to remove the drain line from where its attached to the rear of the machine (one screw) to remove the rear access panel which slides into upper and lower slots. You will see the pump with an inlet and discharge line attached. The lines have simple squeeze clamps. When you remove the lines, you will drain the wash basin so have towels and a squeegie handy. Remove both lines and wait until the basin drains. When it stops draining remove the pumps electrical connector by squeezing the release catch on it while pulling it. The connector can only go on one way. Remove the 3 hold-down bolts on the pump baseplate. Remove the pump and lift open the discharge check valve and you'll find something there I guarantee it. Remove with needle nose pliers and re-assemble in reverse order.
This is actually a good design because the computer protects the pump by sensing a higher than normal current draw when foreign debris gets jammed in it. It will trigger the ND (No Drain) code and sometimes lock the door. Always check this first before you call the expensive repair man. If its not a jammed pump it will most likely be the control panel/processor. Good luck and always clean out pockets before loading the washer to prevent this,
Posted on Feb 14, 2009
SOURCE: LG front load washer -- water leaks
First, clean off the bottom of the door glass where it contacts the gray tub gasket when the door closes. Any hair or other build up can result in leakage. Second, if that does not completely solve your leak, you can move the location of the spring which holds the tub gasket from the very bottom (6 O'clock position) to the hinge area (9 O'clock position). Third: Sometimes, the reason you get a leak is due to the installation. If the washer was pushed into place by applying pressure in the center front of the washer, the outer front panel can be slightly deformed (inwerd) resulting in leakage from the door. If that is the case, sometimes you can remove the outer clamp and outer part of the gray seal and pull out on the front panel to correct the situation if it is not too severe, rather than replacing the entire front panel.
Posted on Jun 25, 2009
SOURCE: Samsung washer is leaking water
I've also had this problem with my machine , it was my brother who found out that the soap drawer has an irregular side over which the water jumps if it pours in with strenght from the tap. that's why the leak seems to be at the front, and only at the beginning of the cycle. We supposed it has to do with using the same drawer for different types of washers. we solved it arranging the low side with american tape and some square flat plastic. Good luck.
Posted on Nov 12, 2009
SOURCE: hotpoint aquarius wf320 1200 spin
its blocked...try the waste pipe
Posted on Nov 14, 2009
Tips for a great answer:
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Jun 16, 2018 | Samsung Washing Machines
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Hope y'all are going to have an awesome labor day weekend! We are heading to Canada for the weekend, so I will be airing reruns of past 'Real Solutions' episodes on social media on Monday.
I was blessed to be on this radio show today! It turned out to be a nice interview!
Check it out here
Remember God has awesome plans for your life. Get excited!


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The Alfred Emergency & Trauma Centre in collaboration with Monash University from Melbourne, Australia, are pleased to announce our annual program of continuing medical education events at the beautiful Monash University campus in Prato, just 40 minutes from Florence, Italy.This year we are offering a Masterclass series to provide development opportunities for senior critical care clinicians in management skills, research productivity and trauma decision-making.
courses are all designed for a diverse international audience with
formats that encourage participant-led, highly interactive learning.
To review the programs for our Masterclass series please refer to the tabs along the top of this web site.
Monash UniversityVia Pugliesi, 26, 59100Prato POItaly
Cvent Online Event Registration Software | Copyright © 2000-2018 Cvent, Inc. All rights reserved.


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Nacra F18 Infusion 2008
BNR Watersport has over 10 years experience in selling used catamarans and everything that is involved in catamaran sailing.
Would you like to have more information, purchase this item, or to receive a quote including delivery, please fill in the form below. We will contact you on a short term.
- Nacra F18 infusion 2008
- Race package
- 4 x adjustable trapezes
- Harken carbo hardware
- Mainsheet 1:10
- Kick up rudders
- Easy lift daggerboards
- Carbon adjustable joystick
- White pinnaker
- White pentax sails 2011
- Rudders refurbished
- Footstraps
- Formule 18 class legal
Variant price modifier:
Salesprice with discount:
€ 8250,00


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03 July, 2014 PIC
The Palestinian Health Ministry on Wednesday said most of Gaza ambulances have gone out of service as fuel reserves have almost hit zero.
Dr. Atef Ramlawi, head of the emergency unit in the ministry, warned, in a press release, that the current situation bodes ill for Gaza ambulances as they might run out of 70% of their overall fuel supplies.
He added: "We've been appealing to officials in the Finance and Health Ministries to step in. But to no avail so far."
No single fuel liter has been bumped into the suspended Gaza ambulances since early July. The ambulances have only been operating in emergency cases.
The Palestinian official warned of the possible inability of meeting the emergency services needed in case of further Israeli raids on the Gaza Strip.
He called on all concerned parties and officials in the unity government to step in with no further delay so as to alleviate Gaza's fuel crisis and cope with such an acute shortage in fuel quantities needed to recuperate Gaza's ambulances.
Observers detected reluctance on the part of health Minister Fathi Awad, located in Ramallah, to deal with the crisis. He has rarely been in touch with the ministry representatives in Gaza.


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KELT Theater Games, etc. will be starting back up on May 12 from 7:00 to 8:30 PM at the QSI International School (163 Mamekuly – just down from Petrovsky's). It is free of charge, and open to all who speak English. If you came and saw "Midsummer Night's Dream" and want to be a part of a future KELT production, we typically draw our cast and crew from our KELT Wednesday night folks – so come be a part of us!
Some things up and coming…
May 12 – Regular Wednesday night meeting starts back up
May 22 or May 29 – KELT picnic – email email@example.com for more information.
June 6 – KELT Film Screening – check back for more information
We will also be doing some fun and interesting things over the summer. Here are some of the possibilities…
• new master's class for acting
• master's directing class
• the first KELT film possibly to be shot
• writing course
If any of these look interesting, email Nathan at email@example.com and let him know!


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Zushibento, Morley
Super Crispy Katsu Chicken (Take-away)
Cuisine: Japanese
I had a craving for Katsu Chicken and some grocery shopping to do on a Saturday, so I decided to kill two birds with one stone and order a Katsu Chicken (take-away) whilst on my way into the grocery store. I had picked up a tray of sushi from here before, and I vaguely remember enjoying a bento box a couple years ago, but I am extremely glad I decided to try the Katsu Chicken this time as it was a great discovery. It was the best Katsu Chicken I have had in a long time, and especially in the area.
Service: The service was friendly and the ladies behind the counter were making fresh sushi.
Food: Katsu Chicken. $10.90
The chicken was super crispy and satisfying. The sauce was delicious, the rice was tender and the creamy majo was plentiful. Along with this, my order came with 2 pieces of California sushi, a small fresh cabbage salad, dressing and soy.
Summary: Reasonably priced. Good food. Fast service. Convenient location. Recommended for Japanese – Especially in the area.


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For those who don't know, it's kind.Drewb and I decided to see what this lcpdfr mod was all about!How To Join the lcpd/Become a Cop In GTA IV (xbox 360, PS3, PC).If you play the game on PC, lcpdfr gives you more options, but you can sunset times seattle march 2014 still have fun on consoles.I lost the audio track that went with it (forgot to save it doh!) so I did a audio lay over, which.GTA IV: lcpdfr.0d 42) - Crazy Suicide Bomber!This video will show you how to "become" a cop in GTA.Mods I'M usingpolice Orders/1B4vMfELS.0lcpdfr.1Door Ajar ChimeStopSticksV1 (by me)Traffic callout modyENB V3Universal Police ComputerImproved cops.1Realistic Vehicle Bullet DamageASP_baton_gtaiv2Running on a AMD FX8350, R9 290 sic Provided.In this video, I am patrolling Liberty City using the lcpdfr mod for.Won't happen again I swear!User contributed content on m is the responsibility of the individual user, pursuant to.S.C.
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Response--BioA: Quast, Joseph (1888 - 1938)
Contact: Crystal
I had found the following information. If you don't understand something, don't be afraid to ask.
Jefferson County Birth Index:
Joseph Quast born 3 Aug. 1857 -- Jefferson County, Reel 0085; Record 002331 Joseph M. Quast born 24 Aug. 1901 -- Jefferson County, Reel 0089; Record 001566 Hugo [index with no first name] Quast born 20 Aug. 1893 -- Jefferson County, Reel 0088; Record 000518
Jefferson County Death Index:
Joseph M. Quest died 8 Feb. 1902 -- Jefferson County, Vol 2; Reel 038 Mary Quest died 16 Sept. 1901 -- Jefferson County, Vol 2; Reel 038
Jefferson County Marriage Index:
Quast, Joseph married 3 July 1888 -- Jefferson County, Vol 4; Page 0024
Wisconsin WWI Registration Cards 01917 - 1918
Hugo John Quast born 20 Aug. 1893; Registration place Clark County, Wis.
1900 Wisconsin, Jefferson County, Aztalan
Quast, Joseph (head) born Aug. 1857 age?, married 12 years, birth place Wis., father & mother birth place Germany, occupation farmer
Caroline (wife) born Mar 1867, age 33, married 12 years, 5 kids, 5 living, birth place Wis., father & mother birth place Germany
Agnes (daug.) born Sept. 1889, age 10, birth place Wis.
Esther (daug.) born July 1891, age 8, birth place Wis.
Hugo (son) born Aug. 1893, age 6, birth place Wis.
Edna (daug.) born April. 1896, age 4, birth place Wis.
Mary (daug.) born Jan. 1899 age ??, birth place Wis.
Fisher, Ewald (nephew) born Feb. 1884, age 16, birth place Wis, father birth place New York, mother birth place Wis.
ED 133, Images 5 & 6, Sheets 3-A & 3-B, Lines 50-57, Date 7 June 1900
Joseph Quast obituary is listed under the obituaries on the ALHN site; death year is 1942. Note the marriage death is wrong in this obituary. The date listed is the anniversary date.
Agnes Quast marriage announcement is also listed in the marriage section on the ALHN site; marriage year 1911.
In the 1930 Census Wisconsin, Milwaukee Co., Milwaukee
Esther Kinnear is living with Robert Kinnear spouse. A son is listed as Futter, Frank F. born 1912.
Social Security Death Index
Edna Dekennen Born 13 Apr 1896 Died Jun 1969 Last Residence: Neillsville, Clark County, Wis. Buried in the St. Mary's Catholic Cemetery: Pine Valley, Clark County, Wis.; Pre ALHN Site
Caroline & Joseph Quast are buried in the St. Mary's Cemetery, Eaton Townshop, Clark County, Wis. You will find Caroline's death date here as well.
Jefferson County Clerk of Courts 320 South Main Street Jefferson, Wis. 5354-1718 Phone: 920-674-7150
I hope this helps in your search. I have no connection to this family line.
Best Wishes, Crystal Wendt
© Every submission is protected by the Digital Millennium Copyright Act of 1998.
Show your appreciation of this freely provided information by not copying it to any other site without our permission.
Become a Clark County History Buff
A site created and
maintained by the Clark County History Buffs
Webmasters: Leon Konieczny, Tanya Paschke,
Janet & Stan Schwarze, James W. Sternitzky,


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The Dr. Phil Show? New Low in Life for Terrell Owens?
Man, T.O… having a rough go at things. Broke, and going on Dr. Phil to have all your baby mamas rip you to shreds. Good luck with that. These clips are from the Dr. Phil show that will air today, … Continue reading
Leave a comment Posted in Football, TV Tagged terrell owens, terrell owens dr. phil


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Headlines 10.30.14 | 07:26AM EDT
Korean agency JYP Entertainment will be holding auditions in China to look for new recruits for their training program in Seoul.
Features 10.31.14 | 07:12AM EDT
Here is our playlist of some of the strangest and creepiest videos in K-Pop, just in time for your Halloween celebrations.
Features 09.08.14 | 09:30AM EDT
JYP artists recently wrapped up their joint concert in Japan.
Events 09.06.14 | 08:01PM EDT
Sunmi Attends Nike Vogue Collaboration Runway Show - Sep 03, 2014 [PHOTOS]
Buzz 09.04.14 | 10:14PM EDT
Boy group 2AM's member Seulong revealed a picture taken with younger members of JYP Entertainment, 2AM's Jinwoon, 15&'s Baek Yerin, and Sunmi.
Buzz 08.30.14 | 03:40AM EDT
Singer Sunmi revealed a closeup self-camera photo.
Events 08.27.14 | 08:01AM EDT
Park Ji Yoon, Sunmi and So Yoo Jin Attend ROSA.K Collaboration - Aug 26, 2014 [PHOTOS]
Buzz 08.18.14 | 07:29AM EDT
K-Pop eye candy for all you fans - directly from the stars themselves
Buzz 08.14.14 | 10:05AM EDT
HA:TFELT Ye Eun shared a photo with three other Wonder Girls members.
Buzz 08.13.14 | 10:05AM EDT
Singer Sunmi took a picture with HA:TFELT, showing an unchanged friendship between the two since Wonder Girls.
Buzz 08.13.14 | 09:43AM EDT
Singer Sunmi and miss A Suzy took a picture with Bernard Park in the middle.
Buzz 08.12.14 | 10:00AM EDT
Singer Sunmi revealed self-camera photos from the backstage of '2014 JYP NATION - ONE MIC'.
Buzz 08.11.14 | 02:15AM EDT
Singer Sunmi revealed a picture taken with Wonder Girls' member Yeeun (HA:TFELT).
Buzz 08.08.14 | 09:39AM EDT
2AM's member Jo Kwon, Sunmi, and GOT7's member Jackson revealed a picture taken together.
Buzz 08.07.14 | 10:13AM EDT
HA:TFELT (Ye Eun) showed her continued friendship with Sunmi.
Headlines 08.06.14 | 10:07AM EDT
The JYP Entertainment stars will be on phone cases.
Buzz 08.02.14 | 07:38PM EDT
Singer Baek Ah Yeon shared a crouching photo of herself.
Buzz 07.30.14 | 11:16AM EDT
2AM Jo Kwon shared selfies of the JYP family.
Buzz 07.24.14 | 01:25PM EDT
Sunmi shared a photo of herself making a gazing face.
Fashion & Style 07.23.14 | 06:07AM EDT
Sunmi looks great with blonde hair as she is featured on the August issue of 'Dazed and Confused'.
Buzz 07.17.14 | 02:56AM EDT
Singer Sunmi showed off her long skinny legs.


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POSTED: Thursday, April 16, 2009
Isle Guard back from Philippines
Thirty soldiers from the Hawaii Army National Guard's 29th Infantry Brigade Combat Team returned yesterday from the Philippines, where they spent six months providing security for humanitarian projects.
Hawaii's citizen soldiers were assigned to the Joint Special Operations Task Force-Philippines, which has been operating since January 2002.
While in the southern Philippines, the Hawaii Guardsmen provided security for engineering, medical support and community outreach projects such as improving schools, hospitals, wells and roads.
Man jailed for urinating on woman
A 28-year-old man accused of urinating on a woman aboard a commercial flight to Honolulu was sentenced yesterday to 21 days in prison, according to a U.S. Attorney's Office news release.
Jerome Kenneth Kingzio, of Saipan, was sentenced by U.S. Magistrate Judge Leslie Kobayashi after he pleaded guilty to assaulting a fellow passenger aboard a March 21 flight from Los Angeles.
According to court documents, Dorothy Reynolds, 66, was halfway into an in-flight movie on Continental Airlines Flight 3 when Kingzio, who had been drinking and disturbing other passengers, got up from one row back and urinated on her arm, side and leg.
U.S. Attorney Ed Kubo said the incident ruined Reynolds' entire vacation and continues to cause her emotional distress.
USS Arizona center to close early
The USS Arizona Visitor Center will close one hour earlier at 4 p.m. April 23 due to a temporary water shutoff because of construction being done in the area.
The last tour of the day will begin at 2:15 p.m., concluding at 3:30 p.m. Normal operations will resume on April 24.
LAHAINA » The Lahaina Public Library monthly book group will discuss ";Born in Paradise"; by Armine Von Tempsky at 6:30 p.m. Tuesday. Von Tempsky, born and raised on Maui in the 1940s and the eldest daughter of a cattle ranch manager, shares her adventures of growing up on the Valley Isle.
LIHUE » Dr. Dileep Bal, Kauai district health officer for the state Department of Health, received the American Cancer Society's 2009 Luther L. Terry Award for outstanding community service at the recent World Conference on Tobacco or Health in Mumbai, India. The program recognizes people worldwide for tobacco and control activities.
Big Island
KONA » Hawaii County and the Department of Hawaiian Home Lands will dedicate a long-awaited connector road in Kona next Thursday. Keanalehu Drive will connect the Kealakehe and Laiopua subdivisions and provide easier access to area schools.


text:
By Rob Parsons
A dozen hunters face federal poaching charges in connection with the deaths of more than 100 waterfowl earlier this year in Sutter County.
The U.S. Attorney's Office filed charges on Friday against the hunters linked to the Jan. 16 alleged poaching in Sutter, according to the complaint filed in U.S. District Court.
Lauren Horwood, a spokeswoman for the U.S. Attorney's Office in Sacramento, said on Wednesday no court dates have been set.
Federal prosecutors filed six misdemeanor counts including unlawfully possessing untagged migratory game birds, unlawful storage of migratory game birds, exceeding the possession limit of waterfowl, white geese, ducks and migratory game birds and unlawful transportation of migratory game birds.
Each count carries a maximum penalty of six months in jail and a $15,000 fine, according to the complaint.
Nevada David Smith, Jeffrey Allen Catlett and Cody Eugene Shogren were each charged with multiple counts.
Smith and Catlett are charged with possessing 134 waterfowl, 41 pintail ducks and 24 white geese. Shogren is charged with possessing 30 white geese. Jeffrey Leroy Dombo is charged with possessing 28 ducks, the complaint says. More....


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Yesterday was the first full day of proper teaching, with the book in the morning and the TBL as the day progressed. The task followed on from the book (Language Leader Upper Int unit 2.5) and involved drawing up a survey questionnaire, and going out amongst the University staff and students and conducting it. They picked it up and ran with! Best bit of teaching/learning I've seen in years. This morning there will be feedback from them in the form of short presentations.
It looks like it's going to work.
Also, they were encouraged to video the surveying, and did. The VLE should look pretty lively if this continues. I've promoted half a dozen students to moderate the Wiki - give them a sense of ownership and give me less work.
The thing I haven't done is to collate all of the test results. Which is a result of the biggest problem I have: being course leader and teaching full time is a considerable time-burden. If I was doing this again, I would draw up a timetable whereby a course leader was doing about 50% of the teaching hours, and the rest of the time would be enough for admin/management.


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N9038W accident descriptionGo to the Nebraska map...
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|Tail number
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|Weatherly 201C
|Clarks, NE
|Additional details:
NTSB descriptionOn May 30, 1995, at 1054 central daylight time, a Weatherly 201C, N9038W, operated by the Platte Valley Aerial Spraying, Incorporated, of Clarks, Nebraska, and piloted by a commercially certificated pilot, was destroyed during a collision with the ground during maneuvering to begin another aerial application swath run. Visual meteorological conditions prevailed at the time of the accident. The pilot was fatally injured. The 14 CFR Part 137 flight was not operating on a flight plan. The flight departed Clarks, Nebraska, exact time unknown.
One witness occasionally saw the airplane during its swath run turn around and related climb. During one of the times he was not looking at the airplane he said he heard the engine suddenly stop followed by a loud "pop."
The Federal Aviation Administration (FAA) Principal Maintenance Inspector (PMI) representing the NTSB on-scene reported no evidence of pre-impact airframe or flight control system failure. He said the engine had been involved in a post-impact fire that was limited to the front of the airplane.
The PMI stated N9038W's carburetor had no fuel in its float bowl. He said the carburetor had been in the post-impact fire. Fuel samples from the airplane were not obtained due to fuel tank rupturing when the airplane collided with the ground.
According to the PMI's report, N9038W's fuel tank selector was on the left fuel tank. The mixture control was "Full Rich" and the throttle was positioned at mid-range. The propeller control was found in the low RPM setting. N9038W's magnetos would not rotate due to collision damage. Steel particles were found in the engine oil screen. A collector drive floater gear (drive gear) tooth was found in the engine sump.
The engine's supercharger impeller drive was found free wheeling when external rotational force was applied to it. Examination revealed 4 1/2 teeth were missing from the drive gear. Three gear teeth from this gear were found in the engine's crankcase housing. A borescope inspection of the engine's cylinder's revealed evidence of "...operation under a rich mixture..." according to the PMI's report.
A representative from P&W stated the gear teeth damage was not from sudden stoppage due to the locations the teeth were found. He said that power interruption could be caused by the teeth breaking away from the drive gear.
Discussion with an FAA Certification Office propulsion engineer revealed that a rich mixture indication found in the engine's combustion chamber would show that the supercharger was not operating adequately. Examination of the super charger's collector drive floater gear unit and separated teeth showed "...typical... overstress separations," according to the NTSB Metallurgical Laboratory.
N9038W's engine logbook showed its major overhaul was completed on February 6, 1990. The last entry in the logbook, February 2, 1995, showed it had 752.92 hours of running time since it had been overhauled. No other engine operating time since overhaul records were found. According to the overhaul records, the engine's collector drive floater gear passed its magnetic inspection on January 29, 1990.
Fuel samples taken from the fuel tank used to fuel N9038W were examined by Petrl Laboratories in Indianapolis, Indiana. The fuel sample examined meets all ASTM specifications for 100LL aviation fuel (ASTM D-910, Detailed Requirements for Aviation Gasoline). Excerpt's from that report are appended to this report.
An autopsy was conducted by Pathology Medical Services, P.C. of Lincoln, Nebraska. The toxicology report from the FAA Civil Aeromedical Institute was negative for drugs, alcohol, cyanide, and carbon monoxide.


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This was our first trip to Joe's on the way back to Charlotte from Wilmington. We read the reviews and were not disappointed. The food, service and friendly atmosphere was well worth the visit.
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South Caringbah
- 4 Beds
- 3 Baths
- 2 Cars
This absolutely stunning 4 bedroom family home in blue ribbon Caringbah South is certainly a home not to miss.
With the charm and character of exquisite led light windows and polished timber floors this amazing home will continually ignite your every inner passion.
The home itself features 4 bedrooms, built in robes, formal lounge, dining, family room, quality Oregan Timber kitchen with granite bench and stainless gas appliances, ensuite, air-conditioning, outdoor rumpus, a breathtaking level yard with plunge pool which is perfect for entertaining or any casual family living.
Finally the home offers a tandem garage and set on a sensational 749m2 block.
A great home in a sensational location.
- Double Garage
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Matthew Cabana
Listed by Bean Group / Amherst
With an eye towards quality and livability, seven years ago this turn-key horse property was taken down to the studs, and has been rebuilt from the inside out. The open-concept great room has a sitting area with a fireplace, an amazing kitchen with tons of granite counterspace, high-end stainless steel appliances, and a dining area with a beautiful bay window overlooking the fantastic outdoor living space. The living room has great built-ins, and there are hardwood floors throughout. The first-floor bedroom currently serves as an office, and there is a half bath too. Upstairs you can have your choice of master suites -- each of them have luxurious baths, walk-in closets and hardwood floors. The mudroom has a resilient slate floor, offers access from the front, garage, and backyard, and has laundry hook ups. Above the two-car garage is a finished room, perfect for an office, family room or guest room. The outside living space is equally spectacular, with a pergola, stamped concrete patio and a screened porch, overlooking a Koi pond, garden space, and a two stall barn for your horses, plus a shed for grain, hay and tack, and a fenced pasture. All of the systems have been updated, the majority of the windows have been replaced, the entire property is fenced, and it is set well back from the road from for privacy. The mini splits and new Buderus furnace keep it cool in the summer and warm in the winter. This turn-key home is beautiful, and ready for you and your livestock!
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Business Analyst
Ajilon is part of the Adecco Group, a Fortune Global 500 company and one of the largest resourcing and recruitment companies in the world. Our client a leading financial organisation based in Edinburgh city centre is seeking an experienced Business Analyst to join their Change and IT team.
In this role you will provide a comprehensive range of analytical services to deliver business solutions which will meet the project objective outlines in the business case. You will ensure that business needs are clarified and challenged, and business requirements are captured to meet both business and IT requirements.
The Business Analyst will:
- Perform a range of analytical services and tasks to ensure that budget for project remains within given constraints
- Create a signed off set of business requirements through critically evaluating and reconciling information
- Gather information through interviews, workshops, document analysis, surveys, site visits, business process descriptions, scenarios, business analysis, task and workflow analysis to identify underlying true needs
- Conduct business impact assessments to determine how changes from the current to future processes and structures will affect business units and roles
- Work with a range of business units, stakeholders and 3rd parties to analyse functional and non-functional requirements, delivering a clear understanding of approach to the business solution to all parties
- Ideally candidates will have experience in a similar role working on varying sizes of projects in a finance or insurance driven environment. The following experience would be desirable:
- Proven ability to establish strong working relationships with internal staff and stakeholders up to and including senior management.
- Experience of working within a business change project/environment
- Relevant experience of advising and influencing managers, up to and including senior managers
- Proven ability to work to deadlines and under pressure
- Knowledge in applying proven methodologies, standards and tools involved in analysis and/or testing
- Experience of the development life cycle and project
Reference: 34563330
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Want more from Genius Kitchen?
Watch on your Apple TV, Roku, or Fire TV and your iOS, Fire, or Android device.Learn More
"Smoked gouda is such a flavorful cheese. You don't need a lot of extra sauces and spices to make this chicken really great. Wonderful for company as well."
Gouda and Spinach Stuffed Chicken Breasts
0 recipe photos
READY IN:1hr
Ingredients Nutrition
- 1⁄2 cup shredded smoked gouda cheese
- 1⁄4 teaspoon ground nutmeg
- 1 (10 ounce) package frozen chopped spinach, thawed and pressed
- 4 bone-in chicken breast halves, with skin
- 1⁄2 teaspoon salt
- 1⁄4 teaspoon pepper
- 2 teaspoons margarine, melted
- Preheat oven to 375 and grease a baking dish, or spray with non-stick cooking spray.
- Combine the cheese, nutmeg, spinach, and then season with extra salt and pepper if desired.
- Remove bones from chicken breasts.
- Do not remove skin.
- Loosen skin from chicken breasts.
- Spread one-fourth of the stuffing evenly between meat and skin of each chicken breast.
- Smooth skin over breasts, tucking under loose areas.
- Place chicken, skin sides up, in pan.
- Sprinkle with salt and pepper.
- Drizzle with margarine or butter.
- Bake uncovered 45 to 55 minutes or until juice of chicken is no longer pink when centers of thickest pieces are cut.
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It may be true that LG G7 won't make an appearance next month at Mobile World Congress (MWC) 2018, but that doesn't mean that flagship was delayed, according to LG. Still, considering the fact the South Korean company usually unveils its flagship for the first half of the year at MWC, we could say that the G7 was postponed.
LG's CEO confirmed early this year at CES (Consumers Electronics Show) 2018 that the G7 development will start from scratch, which is the main reason the smartphone won't be announced next month.
However, LG recently told Android Central that the G7 is right on …


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Frankie's Favorite Moves
This section is dedicated to some of Frankie's Favorite Moves, which should be a staple in any dancer's repertoire. The good thing about Frankie's Favorite's is that many of the moves are simple and goofy, which adds a fun layer to your dancing.
Swing Out with Shuffles
- Start a swing out normally
- On 4, the lead should plant his weight and direct his attention to the right
- The lead should initiate movement to the right. This is easiest done by using the right arm (the one connected to the follow's back) and gently leading the follow to the right with a tug. The lead can aid this visually by looking to the right, pointing, and really moving in that direction
- The lead should shuffle to the right on each half count, almost like a gallop: and 5, and 6, and 7, and 8
- After 8, the lead should initiate a rock step, which will allow him to build momentum to do the next series of moves (whether it's the same swing out with shuffles or another move)
Tip: This move looks best when you cover a lot of distance. Move it!
Pecks are one of the simplest, goofiest, and most fun moves you can do in swing dancing. The basic idea is as follows:
- Stop
- Peck
Leads: when you stop, make sure to really plant your weight so that the follow knows you're not going anywhere


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Int J Pharm Pharm Sci, Vol 8, Issue 12, 310-313Short Communication
aCentre of Excellence for Pharmaceutical Sciences, North-West University, Private Bag X6001, Potchefstroom, 2520, South Africa, bDepartment of Pharmaceutical Chemistry, School of Pharmacy, Faculty of Health Sciences, North-West University, Private Bag X6001, Potchefstroom, 2520, South Africa
Email: email@example.com
Received: 05 Sep 2016 Revised and Accepted: 24 0ct 2016
Objective: This study was aimed at developing an HPLC method that would be suitable and sufficiently robust to analyze clarithromycin or spiramycin from bulk materials, amorphous solid dispersions as well as when included into solid dosage forms.
Methods: A C8 column (250 x 4.6 mm, 5 µm) was used as stationary phase, the mobile phase consisted of 0.1 M dipotassium hydrogen orthophosphate buffer (pH 6.0) and acetonitrile in a 50:50 (% v/v) ratio. The flow rate was set to 0.5 ml/min. UV detection of 210 nm was used for clarithromycin and 232 nm for spiramycin. Ambient column and sample tray temperatures were used.
Results: The method proved to be suitable for the detection of both macrolide antibiotics in bulk samples, as part of amorphous solid dispersions as well as in dosage forms. The isocratic elution was rapid. The method was validated in terms of system suitability, limits of detection (LOD), limit of quantification (LOQ), accuracy, precision, linearity, and specificity. This method showed linearity across the concentration range of 4.0–5000.0 µg/ml for both antibiotics.
Conclusion: The developed method showed to be a simple and sufficiently sensitive method for the detection and quantification of either clarithromycin or spiramycin from samples that might contain even very small quantities of the antibiotics.
Keywords: Clarithromycin, Spiramycin, RP-HPLC
© 2016 The Authors. Published by Innovare Academic Sciences Pvt Ltd. This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4. 0/)
DOI: http://dx.doi.org/10.22159/ijpps.2016v8i12.15058
Recent studies have shown that opportunistic infections of patients suffering from HIV are the cause of 90% of patient morbidity and mortality [1, 2]. The most prevalent and life-threatening opportunistic infections among people living with HIV in different populations include Mycobacterium tuberculosis, Pneumocystis jirovecii pneumonia, Mycobacterium avium complex (MAC) and Cryptosporidiosis [1, 3]. Azithromycin and clarithromycin are currently the two macrolide antibiotics of choice prescribed for the prophylaxis and treatment of MAC opportunistic infections in HIV patients [4]. Cryptosporidiosis is a life-threatening infection that is very difficult to treat since it causes cholera-like diarrhoea with the profuse daily fluid loss of about 17 liters [5]. Spiramycin is one of the macrolide antibiotics recommended for treating cryptosporidiosis among immunosuppressed individuals [6, 7]. Considering the global dilemma of antimicrobial resistance, there is currently a renewed focus on antibiotics that were not usually the drug of choice for the treatment of certain infections. Spiramycin is one such drug. During our research on clarithromycin and spiramycin, we identified the need for a suitable and single HPLC method that could be used for the identification and analysis of both drugs. Especially, considering that the British Pharmacopoeia (BP) only reports on an HPLC method that is suitable for the analysis of spiramycin from veterinary formulations [8]. No another pharmacopeia contains an analytical method for spiramycin. Furthermore, the methods included in both the BP and the United States Pharmacopoeia [9] for clarithromycin uses high buffer concentrations, and those methods lead to long HPLC run times.
Clarithromycin is classified as a semi-synthetic antibiotic which forms part of the macrolide group. This antibiotic is derived from erythromycin but differs in the fact that the O-methyl group has been substituted for a hydroxyl group at position six of the lactone ring (fig. 1a) [10]. Spiramycin consists of a 16-membered lactone (platenolide), two amino sugars (D-mycaminose and D-forosamine) and one neutral sugar (L-mycarose) (fig.1b). Spiramycin has three major (I, II, III), three minor components (IV, V, VI) and two other additional spiramycins 18-deoxy-18-dihydrospiramycin (DSPM) and 17-methylenespiramycin. Though spiramycin I is shown to be the main component, the quantity of each component varies according to the manufacturer [11-13].
Fig. 1: Molecular structure of (a) clarithromycin and (b) spiramycin [8]
The objective of this study was to develop an easy, cost-effective but sufficiently robust RP-HPLC method for the detection of clarithromycin or spiramycin. The rationale for this was that the current methods that are available in the literature for both drugs use high concentration buffers as part of the mobile phases and in the instance of clarithromycin, gradient elution is being applied. Therefore, this is a simple method with the ability to accurately detect and quantify both drugs, thereby making it very useful for laboratories that need to analyze both macrolide antibiotics.
Clarithromycin working standard (97.7% purity) and spiramycin (purity of 94.9%, only spiramycin I) were purchased from Sigma-Aldrich (Johannesburg, South Africa) and DB Fine Chemicals (Johannesburg, South Africa). HPLC grade acetonitrile, potassium dihydrogen orthophosphate and hydrochloric acid (32%) were purchased from ACE Chemicals (Johannesburg, South Africa). The pharmaceutical dosage form used during specificity testing was Clacee® 250 mg tablets (Aspen Pharmacare, South Africa). In the case of spiramycin, no commercial product was available for purchase and therefore a mixture of typical pharmaceutical excipients was made. This mixture constituted of microcrystalline cellulose, polyvinylpyrrolidone (PVP) K 30, magnesium stearate, talc and croscarmellose sodium. All the excipients used were a kind donation from the Department of Pharmaceutics of the School of Pharmacy, North-West University, and Potchefstroom, South Africa.
A Shimadzu (Kyoto, Japan) UFLC (LC-20AD) chromatographic system, equipped with an SIL-20AC autosampler fitted with a sample cooler, a UV/VIS PDA detector (SPD-M20) and an LC-20AD solvent delivery module was used during the method development and validation. A Phenomenex® Luna C8 5 µm, 250 x 4.6 mm column was used as stationary phase. The mobile phase consisted of 0.1 M phosphate buffer (pH adjusted to 6.0 with 0.1 M HCl) and acetonitrile in a ratio of 50/50 %v/v. Isocratic elution was used with a flow rate of 0.5 ml/min. An injection volume of 10 µl was used for the analysis and validation of clarithromycin while an injection volume of 2 µl was found to be suitable for spiramycin. For the detection of clarithromycin, a wavelength of 210 nm was used while spiramycin was detected at 232 nm [9]. For both antibiotics, stock solutions were prepared by separately and accurately weighing 50 mg of drug and diluting it to 10 ml with mobile phase. This resulted in a stock solution of 5000.0 µg/ml, for each drug. Aliquots of these stock solutions were then diluted with mobile phase to obtain standard solutions with concentrations ranging from 4.0–5000.0 µg/ml. Each standard solution was filtered using a 0.45 µm PVDF filter into HPLC vials.
During the preparation of product sample for the testing of the specificity of clarithromycin, 10 tablets were weighed and grinded using a mortar and pestle. In the case of spiramycin, a sample was prepared as discussed previously described. For each drug sufficient sample powder was weighed, equivalent to result in a final drug concentration of 1000 µg/ml. Each sample was diluted with mobile phase. The flasks were shaken for 10 min using an ultrasonic shaker. Thereafter each sample was filtered through a 0.45 µm PVDF filter into HPLC vials.
The method was validated as specified by the ICH guideline on the validation of analytical procedures (ICH) [14]. Linearity, range, precision, accuracy, recovery, specificity, limit of detection (LOD) and limit of quantification (LOQ) were the validation parameters. For each drug, eight standard solutions with concentrations over the stated working range were analyzed in duplicate. This was done during two different times by two different analysts. From the obtained data, regression plots of peak area versus drug concentration provided linear regression data as stipulated in table 1.
Table 1: Validation parameters determined during method validation for the detection and quantification of clarithromycin and spiramycin
|Validation parameter*
|Linearity range (µg/ml)
|Correlation coefficient (r2)
|Regression equation
|y = 505.55x–9083.33
|y = 14801x-276251
|Recovery (%) (±% RSD)
|LOD (µg/ml) (±% RSD)
|4.0 (±6.6 %)
|1.5 (±12.9%)
|LOQ (µg/ml) (±% RSD)
|16.0 (±0.36 %)
|8.0 (±0.13%)
*The validation parameters were determined from the analysis of eight standard solutions (n = 8) over a concentration range of 4.0–5000.0 µg/ml. %RSD: Percentage relative standard deviation. LOD: Limit of detection, LOQ: Limit of quantification.
The recovery obtained with this method proved to be acceptable for both drugs, due to the fact that the recovery was between the limits of 98.0–102.0%. The determined LOD and LOQ limits for this method also proved to be acceptable with very small concentration levels of both drugs being detectable and quantifiable. The accuracy of the proposed method was tested at clarithromycin concentration levels of 250.0 µg/ml and 1000.0 µg/ml. The recovery for clarithromycin was determined to be between 98.32–101.64%, with a mean recovery of 99.95% and a percentage relative standard deviation (%RSD) of 1.25%. For spiramycin concentration levels of 250.0 µg/ml and 1030.0 µg/ml was used for accuracy testing. The results showed recovery between 98.21–101.10%, with a mean recovery of 99.65% (±1.02%). From these results, it can be concluded that the method delivers accurate results. The precision of the method was investigated through determination of repeatability and intermediate precision. The repeatability for both drugs was determined at concentration levels, 200.0, 500.0 and 1025.0 µg/ml, the samples were analyzed in triplicate (table 2).
Table 2: Summary of repeatability data obtained for clarithromycin and spiramycin
|Theoretical concentration (µg/ml)
|Mean clarithromycin concentration (µg/ml)±%RSD*
|Mean spiramycin concentration (µg/ml)±%RSD*
|210.44 (±0.05)
|213.43 (±0.56)
|511.16 (±0.62)
|513.88 (±0.18)
|1030.45 (±0.84)
|1020.73 (±0.28)
*Each reported value is the mean±%RSD of n observations. For repeatability, n is 3. %RSD denotes the percentage standard deviation
The intermediate precision was measured during three different sampling times. Samples were prepared by different analysts as well and analyzed in duplicate. The resulting data is presented in table 3. The % RSD for these determinations were not more than 5.0 % and were therefore deemed as sufficient proof of the precision of this method.
Table 3: Summary of intermediate precision data obtained for both drugs. Samples were analysed on different days, by different analysts
|Theoretical concentration (µg/ml)
|Mean clarithromycin concentration (µg/ml)±%RSD
|Mean spiramycin concentration (µg/ml)±%RSD
|(1) 999.29 (±0.11%)
|(1) 1017.43 (±1.45%)
|(2) 995.53 (±1.91%)
|(2) 1018.05 (±0.59%)
|(3) 1018.89 (±0.58%)
|(3) 1019.82 (±0.12%)
*Each value is representative of the mean±%RSD of n observations. For the determination of intermediate precision, n is 3. %RSD denotes the percentage standard deviation.
The specificity of the method was tested by analyzing the prepared sample solutions which contained typical formulation excipients. Fig.2 depicts the chromatograms obtained for clarithromycin standard and sample solutions while, fig. 3 depicts the chromatograms obtained for spiramycin standard solution and the sample solution prepared in combination with the mentioned excipients. No peak interference of any of the excipients was observed and therefore the method was deemed suitable for the analysis of formulated dosage forms containing either of the macrolides. The presented results show that the developed method is accurate, precise and specific. A simple HPLC method was developed and validated for the detection and quantification of either clarithromycin or spiramycin. The method proved to be accurate and reproducible and to be suitable for the analysis of either clarithromycin or spiramycin either as bulk drug or when in combination with typical pharmaceutical excipients.
Fig. 2: Chromatograms obtained for clarithromycin during specificity testing with chromatogram (a) showing the peak obtained for clarithromycin from a standard solution and (b) showing the peak obtained for clarithromycin detected from a commercial sample
Fig. 3: Chromatograms obtained for spiramycin during specificity testing with chromatogram (a) showing the peak obtained for spiramycin from a standard solution and (b) showing the peak obtained for spiramycin detected from a commercial sample
This work was carried out with the financial support of the National Research Foundation of South Africa (NRF) (Grant no. TTK13020718661) and the Centre of Excellence for Pharmaceutical Sciences, (Pharmacen) of the North-West University, Potchefstroom Campus, South Africa.
Declared none
- Iroezindu MO. Disparities in the magnitude of human immunodeficiency virus-related opportunistic infections between high and low/middle-income countries: Is highly active antiretroviral therapy changing the trend? Ann Med Health Sci Res 2016;6:4.
- Rubaihayo J, Tumwesigye NM, Konde-Lule J. Trends in the prevalence of selected opportunistic infections associated with HIV/AIDS in Uganda. BMC Infect Dis 2015;15:1.
- Sepkowitz KA. Opportunistic infections in patients with and patients without acquired immunodeficiency syndrome. Clin Infect Dis 2002;34:1098-107.
- Davis S. Macrolides and ketolides: more than just antimicrobials. Southeast Asia Psychol J 2011;78:24-7.
- Sprinz E, Mallman R, Barcellos S, Silbert S, Schestatsky G, Bem David D. AIDS-related cryptosporidial diarrhoea: an open study with roxithromycin. J Antimicrob Chemother 1998;41 Suppl B:85-91.
- Huang MZ, Li J, Guan L, Li DQ, Nie XM, Gui R, Chen X. Therapeutic effects of acetyl spiramycin and garlicin on cryptosporidiosis among drug users. Int J Parasitol: Drugs Drug Resist 2015;5:185-90.
- Wang D, Zhang YY. Intestinal pathological changes of Kunming mice infected by Cryptosporidium and the therapeutic efficacy of spiramycin on infected mice. Zhongguoji sheng chongxueyuji sheng chongbingzazhi. Chin J Parasitol Parasitic Diseases 2014;32:225-8.
- British Pharmacopoeia. The Department of Health. Vol. VI. London: The Stationery office; 2016.
- United States Pharmacopoeia-39. National Formulary-34; Pharmacopeial forum; 2016. p. 8027.
- Li W, Jia H, Zhao K. Determination of clarithromycin in rat plasma by HPLC-UV method with pre-column derivatization. Talanta 2007;71:385–90.
- Maher HM, Youssef RM, Khalil RH, El-Bahr SM. Simultaneous multi-residue determination of metronidazole and spiramycin in fish muscle using high-performance liquid chromatography with UV detection. J Chromatogr B 2008;876:175–81.
- Oka H, Harada KI, Suzuki M, Ito Y. Separation of spiramycin components using high-speed counter-current chromatography. J Chromatogr A 2000;903:93–8.
- Wang MJ, Pendela M, Hu CQ, Jin SH, Hoogmartens J, Van Schepdael A, et al. Impurity profiling of acetyl spiramycin by liquid chromatography-ion trap mass spectrometry. J Chromatogr A 2010;1217:6531–44.
- http://www.ich.org/fileadmin/Public_Web_Site/ICH_Products/Guidelines/Quality/Q2_R1/Step4/Q2_R1__Guideline.pdf. [Last accessed on 25 Aug 2016].
How to cite this article
- Runako Masline Katsidzira, Anita Wessels, Marique Aucamp. A novel RP-HPLC method for the detection and quantification of clarithromycin or spiramycin in bulk drug samples and dosage forms. Int J Pharm Pharm Sci 2016;8(12):310-313.
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Given the hype surrounding Fortnite right now, it's pretty incredible that developers have been able to get a fully featured version of the game for mobile devices, and Epic Games has insisted that there will be more to come in the future.
You'll be able to sign up starting Monday, March 12th for the Invite Event on iOS.
It's also reported that Fortnite Battle Royale on mobile will eventually support cross-play and cross-progression between the PlayStation 4, PC, Mac, iOS, and the Android versions of the game. One of the bigger changes is the way Battle Royale teams can now organize themselves into groups of 20.
"If you don't receive an invite right away, don't worry". That being said, Epic promises to invite lots of players over the coming months. But that is only if a person from a squad invites a friend from another platform.
As it is a robust game, Fortnite requires the following devices at minimum: iPhone 6S/SE, iPad Mini 4, iPad Pro, iPad Air 2 or a 2017 iPad. The Android version will be out at a later date. So, iOS users will be able to take on Android when the support arrives. Given the oversaturation of zombie-themed games of late, you'd think the "Minecraft slash Left 4 Dead" four-player co-op would become just another title on Epic's belt.
Although Fortnite Battle Royale is free to download, if you're playing on Xbox One you will have to pay for Xbox Live Gold to play online. Your progress will also sync across the platforms. While it does suck that Android is always treated as the redheaded stepchild of mobile, at least we know a release is planned.
What is the Fortnite App?
Fortnite Battle Royale is the direct competitor for PUBG but not anymore as the massively multiplayer online game is about to go all mobile expanding its horizon. Your parents old phone won't be enough to play this one.
You need to be logged in to post a comment. But to clear up any confusion, think as Fortnite as two games.
It's safe to say that Fortnite is a cultural phenomenon at this point. Also, Fortnite runs perfectly on console, allowing access to a much wider audience than PUBG.
Samsung Galaxy Note9 reportedly not coming with in-display fingerprint scanner
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Gold slips on N.Korea news, market awaits USA jobs data
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Xiaomi to launch 'slim, sleek and compact powerhouse' smartphone on March 14
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Warriors lose Curry but still beat Spurs
Curry walked to the locker room immediately to get his ankle re-taped and perform unspecified functionality tests. Warriors coach Steve Kerr said Curry would not play at Portland on Friday or at Minnesota on Sunday.
You can get some 'Mario Kart' in Google Maps starting today
With Mario Day is right around the corner (March 10- MAR10 ) it looks like Google is putting on a little celebration. My favorite game for it was Mario Bros. - it was before the brothers became super on Nintendo Entertainment System.
U.S. top diplomat in Kenya for three-day visit
Trump's latest budget proposal in February slashed spending for Africa by 37%, down $3.1 billion from current levels. He also said the country had a "problem" with its judiciary that needed to be fixed.
Turkey termed as 'triangle of evil' by Saudi prince
During the meeting, they reviewed the Saudi-British relations in various fields and the opportunities to develop them. Foreign policy issues, including Yemen and Iran, are expected to feature in the talks.
Chip & Joanna Gaines Announce the Gender of Baby Number 5
Oh, and one more fun thing we got to see this weekend is a more obvious baby bump on Joanna , free from flowy dresses. When Joanna posted a video of her sonogram her hubby at the time was certain he knew the sex of their fifth child.
Kawhi Leonard Wants to Finish Career with the Spurs
They understand the situation that I'm in. "We don't want to take any steps back and just aggravate things", Leonard continued. I feel better, and I'm feeling more comfortable", Leonard told reporters on Wednesday (Thursday AEDT), via ESPN .
Technical issue causes huge delays at Sydney Airport
It affected systems including the airport's CCTV, meaning passengers could not be screened for about two hours. All the systems were operating as normal by late morning, the airport said in its Twitter page.
Alabama Basketball: Sexton's Buzzer Beater Lifts Tide in SEC Tourney
Vegas has been spot on when setting the O/U total of Aggies games, with an even split between overs and unders. The Alabama Crimson Tide (17-14) are riding in a five-game losing streak before entering the postseason.
Delegates endorse lifting term limits for China's presidency
But the U.S. defense budget continues to be several times larger than China's, military experts argued. "It's an evolution. China will also actively expand imports this year as it aims to further open up its market, said Li.
Android P final release coming Q3 2018
Devices are now also able to subscribe to different update channels thanks to the new APIs that have been added to UpdateManager. I personally think that anything involving "Pie" is not sweet enough, not to mention that pies do not come in many colors.
Mavericks owner Mark Cuban denies 2011 sexual assault claim
According to the report, the woman waited more than a week before contacting the police. Cuban denied the allegations in an email to the paper, saying, " It didn't happen ".
IL sees 66 percent jump in emergency room visits for opioid overdoses
The Chicago Tribune reports the Centers for Disease Control and Prevention on Tuesday released state emergency room data . And common painkillers don't have side effects, such as leading people into opioid addiction, the study concluded.


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I am Noa Berger, VizEat's Community Manager (http://bit.ly/Wf1vx3). We connect locals and travellers who'd like to discover a new culture with hosts who welcome them at their home around a meal.
Using VizEat is very easy and straightforward: hosts post their meal (this could also be an aperitif, brunch, wine & cheese, etc.) select a date & price, choose their guests and then share an authentic moment around a home cooked meal!
I love your blog and so would be delighted to discuss a potential partnership. There are numerous mutually beneficial opportunities that we can present to you.
Would you be available for a 10 minute chat so that I can give you more details about the partnership and what we are proposing?
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Kind regards,
Noa Berger
Community Manager