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Crowds gathered to have a blast at, and show support for, the Eaton Foreshore Festival on Sunday, March 11.
Patrons flocked to the showgrounds, close to Pratt Road, to experience the festival's share of rides and carnival attractions fit for the whole family.
The event also delivered a slew of market stalls and food vendors from 8.30am to 2pm.
Eaton Foreshore Festival was first held in 1991 to help raise funds for Eaton Primary School.
The event is now run by a dedicated group of parents, teachers and community members each year.
Bunbury Busselton Towing, Shire of Dardanup, Dynamite Dan's Cleaning Services, Kuza Coffee, Onsite Rental Group, Gravity, and The Print Shop helped in pulling the event together.
Read more:


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Several years ago, Sara Taggart started noticing she was losing a lot of hair whenever she took a shower. As she combed it, more hairs would end up in the sink. Then one day she noticed a patch of bare skin on the back of her head--a bald spot.
Taggart, who manages a private estate in Baltimore County, was distraught. Her mother had lost a lot of her hair in her 60s and 70s, gradually becoming bald. But Taggart was only 53.
"I was afraid this was going to happen to me, too," she says. "My family started noticing I was losing my hair. Then my friends said, 'Oh my goodness, you're losing a lot of hair.' It was making me so uncomfortable and depressed, I started shopping for a wig. Then I said 'No! I've got to go for help.' "
After thoroughly examining her to rule out any medical reason for hair loss, dermatologist Robert Weiss prescribed spironolactone. A diuretic commonly used for high blood pressure, spironolactone also blocks androgens, male hormones that can accelerate hair loss. Taggart's hair has grown back healthy and thick.

subset: commoncrawl


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Note: Women generally tend to lose hair in a diffused pattern whether it is beginning, mid/progressive, or advanced.
Measure from side to side (W) and front to back (L). It is important that the area outside your measurement has a sufficient amount of hair for topper clips to attach to – include that area with your final measurement.


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This is definitely the most colorful and unique fence I've ever come across. It must have been a labor of love!
I love it!!!!!!!
Dear Madelaine………..Now, if someone would attach a bird house to each fence post where the hole is , this would be a real attraction for all
the birds in the neighborhood………a bird resort of sorts….great picture as usual…………you do have a talented eye, Madelaine…


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A SHALLOW grave may have been dug for a hiker feared murdered, a whistleblower ex-cop revealed.
Kenny McKechnie said an off-duty officer stumbled on a pit in a forest near where Nicholas Randall, 30, was found dead in a tent a year later.
And he said the 6ft long, 3ft deep trench fuelled colleagues' suspicions of foul play, despite the cause of his death being "unascertained".
Kenny, 47, said: "The cop found the grave when he went into the woods as he needed the toilet.
"He didn't report it for days as I think he was a bit embarrassed.
"When Nicholas was found a lot of cops thought it was connected.
"The road between the spots was quiet so it would be easy to move a body. Did a killer intend to bury Nicholas but changed his mind?
Another force source said: "It was expertly dug and looked like it was just waiting for a body. The Forestry Commission had no knowledge of it."
Town planner Nicholas, of Blackhall, Edinburgh, vanished in 2005. His car was found 47 miles away.
The pit was found in 2007, and his remains were discovered in 2008 in Auch Forest, near Bridge of Orchy.
We told how Kenny believes top brass ignored evidence he was camping with a pal, including two sets of clothes and a used condom.
But cop chiefs insist they carried out a "thorough investigation".
Watchdog probe demand
TORIES demanded a probe by watchdogs into how cops handled Nicholas's death.
Justice spokesman Liam Kerr said: "There seems to be enough here to cast doubt on the police's initial findings.
The least his family deserve is for the case to be checked out."
The Police Investigations and Review Commissioner said it has not been instructed to investigate.
We pay for your stories and videos! Do you have a story or video for The Scottish Sun Online? Email us at firstname.lastname@example.com or call 0141 420 5266


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How do I sign up for a Health First Colorado health plan?
By Webmaster / June 17, 2016 /
First, you should review the different Health First Colorado plans and decide which one is the best one for you. See the Choose a Health Plan page or call Health First Colorado Enrollment at 303-839-2120 (in Denver) or 1-888-367-6557 (outside of Denver). Hours: Monday-Friday, 8:00 a.m. to 5:00 p.m. (closed state holidays). Note: The Health First Colorado Enrollment number is not for information on benefits or to find out if you qualify.


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Wants to Meet Up
- Last login 20 days ago
Join Couchsurfing to see Anna's full profile. It's free!
About Me
Save the world :)
I work in the theatre, so if I am at the first meeting accidentally become talking about Meyerhold or Brecht - do not pay, please, attention, everything is okay ;)
It's easier to live without love. But without it there's no sense to live.
I love theatres, dogs, local sweets (even strange for most people, just like licorice. I love it!) snow, concerts and postcards (absolutely adore as send as receive them).
- theater
- folklore
- music festivals
- cooking
- white wine
- wine tasting
- music
- classical music
- folk music
- entrepreneurship
- history
- languages
- language exchange
- travel
Music, Movies, and Books
I'm really big music fan and range of my favourite music begins from R.Wagner or F.Liszt and can ends by Depeche Mode, Gusgus and so on. Except them my favourite are Queen, Mgzavrebi (amazing georgian guys), Sting and I adore musicals. Like Les Miserable, Notre Dame de Paris and more and more.
I like fairy-tales of Andersen and novels of Hugo. Also, I adore poetry. In every language. :)
One Amazing Thing I've Done
I was kissed on the cheek by Brian May :)
Teach, Learn, Share
I can teach you how to cook russian classical blinchiki. Best of them from all over the world.
Also I can share with you with that rare information about Belarusian modern music (even give to listen ;)
What I Can Share with Hosts
Everything I have :)
Countries I've Visited
Austria, Czech Republic, Egypt, France, Georgia, Germany, Israel, Italy, Lithuania, Monaco, Montenegro, Palestine, Poland, Russian Federation, Slovakia, Turkey, Ukraine
Countries I've Lived In
Belarus, Czech Republic, Germany


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Lighthouse of Brookfield
16720 W Greenfield Ave Brookfield WI 53005 (888) 848-5698
About Lighthouse of Brookfield
Lighthouse of Brookfield is an Alzheimer's and dementia care provider in Brookfield, WI 53005. Memory care is most often provided in a separate unit of an assisted living facility or a nursing home, but some communities may specialize solely in caring for residents with memory issues. Levels of care can vary significantly between facilities. One provider may only offer limited assistance to residents, while another may provide comprehensive care for individuals who are in the later stages of dementia. Memory care provides residents with a safe environment that limits wandering and experienced staff who can meet their unique care needs.
Reviews for Lighthouse of Brookfield
Lighthouse of Brookfield


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I'm not a big fan of textbooks. Which is kind of odd, because I love both reading and learning. But textbooks themselves… they're usually dull, boring, uninspiring, and hard to learn from.
I have had the occasional good textbook. You know, the one you wanted to keep either as a resource or because you actually enjoyed reading it? For resource ones, I've had decent ones on Perl and C that I've actually used since I originally bought them for a course. And I had a textbook, that I can't find right now and so can't share the name of, for a "computers and society" class that was actually a really interesting and engaging read.
One of my grad classes required a couple of the "a very short introduction" books, which are easy reads and informative. They were used as a way to help students get some of the necessary background information, as we were coming into the class with various backgrounds. At some point, I'd actually like to take the time and read more books from this series.
In one of the first grad courses I took, we were given the opportunity to review a chapter from an upcoming textbook. The goal (for extra credit) was to give feedback on what we liked/disliked as well as any errors we found. It was definitely an interesting experience to be on the 'other side' of textbooks for a change. It's much different reading a textbook with a critical eye on how it was written and is it correct then when you normally read one and just expect everything to be good (even if they often aren't).
Today, through an article at The Chronicle, I was introduced to Thanks, Textbooks on tumblr. All the posts are pictures of bizarre problems and images that have managed to get published in textbooks over the years. Such as how to do the donkey calf raise and learning probability based on the likelihood a guy will cheat on his wife. I'd call it a time waster, but there really aren't a lot of posts yet, so it doesn't actually take much time to make it through them all. But I did burst out laughing from a bunch of them.
As I am no longer taking classes, and rarely get the chance to TA (:(), I don't get to interact with textbooks much anymore, besides ones I pick out myself or already have on my shelves. I am interesting the e-textbook movement, especially with the idea of building books like the iBooks which allow for interactive media to be embedded within. But, I'm not sure if making textbooks "flashier" will actually solve the larger problem of how do you get students to actually read an entire chapter.
For most of my classes, I preferred attending the lectures over reading the textbooks (although I usually did both). However, there was the odd class where the textbook ended up being way better than the class, but that was usually more a comment on the instructor's teaching style then the textbook actually being all that great.
I do wonder how much better teachers and learners many of us would be, if we were required to spend some time writing part of a textbook (whether or not it was every published). But more for the experience of having to figure out a good way to explain information to someone else, in a setting where they can't ask you questions to clarify what you meant, and having to really think about how you can practice the skill you are trying to teach and test if it is known. It'd probably also make many of us much more sympathetic to some of the teachers of our pasts.


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the camera is now displaying an (E) where the number of shots taken is usually displayed." "Remove the batteries, put lens aperture ring on f22 (or f16)..." Has absolutely nothing to Make sure the camera is set to program (P) or aperture-priority (A) exposure mode. (Slow sync is also set automatically in Night mode.)2. Once complete the Dark Frame and the original are summed together so that the noise is cancelled. I believe you are right - he is probably just not waiting long enough for NR to complete and he is probably shooting at very high ISO values. click site
Reply 27) ralfwolf March 23, 2015 at 5:19 pmIt is worth mentioning since many people are confused about this but on Nikon DSLRs the r followed by a two digit number If you want to find out how to do it in details, check out my "How to fix blinking ERR error on new Nikon DSLR cameras" article.If you have tried cleaning It flashes on the screen until it has completed the process, and whilst it is doing so the camera locks up. Reply Reply with quote Complain mtlr • Regular Member • Posts: 294 Re: fEE Error on nikon d7000, aperture ring is already locked In reply to jamiesmithnc • Mar http://photo.net/nikon-camera-forum/00WyW4
harpo95993's gear list:harpo95993's gear list Sony RX100 Konica Minolta Maxxum 7D Nikon D7000 Nikon D7100 Nikon AF-S DX Nikkor 16-85mm f/3.5-5.6G ED VR +18 more Reply Reply with quote Thanks! If you do not know how to format a memory card inside your camera, see your camera manual for instructions.
However, if you hold the shutter release button, it will take pictures after about a 3-second delay. Answer ID 2605|Published 05/08/2003 03:58 AM|Updated 10/10/2016 03:32 PM The FEE error indicates that the cameracannot control the full range of the lens aperture. Email *Required Your Feedback *Required Answers others found helpful My camera shows "Err" on the top LCD, what does that mean? Nikon D7100 Error Codes I will post an update when it gets back.
If everything else fails, can the NIKON toll-free helpline for free tech help. Fee Error Nikon I will post an update when it gets back.Please do, Jamie, I just got my new D7000 with the same fEE error problem on all 3 AFD lenses I own (35/2, If either of the two items above are broken or damagedplease contact yourreturn your equipment for service. Read More Here Menu Search titles only Posted by Member: Separate names with a comma.
Om Press Upphovsrätt Innehållsskapare Annonsera Utvecklare +YouTube Villkor Sekretess Policy och säkerhet Skicka feedback Pröva något nytt! Nikon D7000 Error Codes Rankning kan göras när videoklippet har hyrts. How do I get the file on my mobile device? E implies either improper fiilm loading (or it thinks that) or non-DX film is in place (or it thinks that too).
Stäng Ja, behåll den Ångra Stäng Det här videoklippet är inte tillgängligt. http://www.apug.org/forum/index.php?threads/problem-with-the-nikon-n60.17039/ skintribe 2 105 visningar 2:20 Nikon 50 mm f1.8 lens broken notch FEE ERROR - Längd: 3:04. Nikon Error Codes that shows up where the remaining frames when the shutter release is half pressed is *NOT* an error code. Nikon D90 Error Codes Reply 23) Jody Lawrence April 14, 2014 at 3:34 pmThankyou very much for this advice, have been very worried for the last few hours after repeated error message after every couple
Påminn mig senare Granska En sekretesspåminnelse från YouTube – en del av Google Hoppa över navigeringen SELadda uppLogga inSök Läser in ... http://thepromo.net/error-codes/nikon-error-messages.php Guess ya don't have a manual? genece's gear list:genece's gear list Panasonic Lumix DMC-FZ30 Nikon D50 Nikon D7000 Nikon D7100 Reply Reply with quote Complain sillyconguru • Veteran Member • Posts: 3,057 Re: fEE Error Check that the lens' aperture ring hasn't suffered any damage.The lens looks fine as well. Nikon D80 Error Codes
Läser in ... Pull the film leader across to the red index mark in take-up area.5. Turn the exposure mode dial on the top of the camera to the sports mode icon.To cancel, select any other exposure mode—Auto, P, S, A, M, or any of the other navigate to this website And, in the middle there is a flashing plus sign with mini "ruler".
Forums Unified View Minox All Forums Mirrorless Digital Cameras Accessories Modern Film Cameras Alternative Cameras & Lenses Nature B&W - Film & Processing New User Introductions B&W - Printing & Finishing Nikon D750 Error Message I have used the AF G lens in manual mode with good results also. Placing a Flower Photo on a BackgroundPortrait Photography: Fixes and Tips in Lightroom (Video Tutorial)Nikon 50mm f/1.8G AF-S FX Review Latest Equipment Articles Nikon Announces 70-200mm/f2.8 E FL AF-S VR and
Visningskö Kö __count__/__total__ Ta reda på varförStäng Nikkor 50mm 1.8 D FEE error soheilshah1 PrenumereraPrenumerantSäg upp8989 Läser in ... Prime Studios 245 698 visningar 3:07 Err sur Nikon D80 - Längd: 1:09. The fastest sync speed is 1/125 second.N60/F60 Aperture and Flash Range(in feet, at ISO 100)Aperture — Flash Rangef/1.4 — 6.6–35 feetf/2 — 4.6–25f/2.8 — 3.3–17f/4 — 2.3–13f/5.6 — 2.0–8.9f/8 — 2.0–6.2f/11 F-- Error Nikon Is it something wrong with the camera?
Thanks Reply Reply with quote Complain jamiesmithnc OP • New Member • Posts: 5 Re: fEE Error on nikon d7000, aperture ring is already locked In reply to jamiesmithnc Unfortunately, that didn't help either. Reply 4.2) Richard Peters Photography November 27, 2010 at 8:21 amJo, what is the shutter speed and ISO you are using when getting this message? http://thepromo.net/error-codes/nikon-error-messages-d90.php Reproduction in whole or part in any form or medium without specific written permission is prohibited.
charlene louw 20 742 visningar 3:27 5 Reasons Why You Need a 50mm lens - Längd: 10:10. Logga in 52 6 Gillar du inte videoklippet? Hold down the +/- button (on the top of the camera).2. what happens from dry-firing a camera?
Created by PGraham3 Oct 21, 2016 at 4:03 AM canon fd lens Created by CMoore Oct 20, 2016 at 8:26 PM FS: Pentax K1000 w/ 50mm... This only matters if the Aperture ring is set to anything other than the smallest aperture correct? the lcd just says "err" on it. I formatted memory card, tried a new memory card but still the same error was displaying.


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2 Canadian invaders busted with 159 pounds of Ecstacy
June 14, 2011 Leave a comment
Spokane (Wash.) Spokesman-Review
Two Canadian men were arrested near the United States border with 159 pounds of Ecstasy, authorities said today. — Christopher S. Stocken, 31, and Joshua J. Bird, 23, appeared in U.S. District Court in Spokane this afternoon to hear their charges. — The suspects were booked into the Spokane County Jail Saturday about 3 p.m. after being arrested in the Colville area, the U.S. Border Patrol confirmed. — They face charges of possession with intent to distribute Ecstasy and importation of Ecstasy. A hearing to determine if they can be released from jail on bail is scheduled for Thursday… Read More


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Latest News
Nothing shows how pagan we are like the sacrifices we make. I know that for many "sacrifice" sounds uber-religious...
Mother's Day
I trust you had a wonderful Mother's Day. My apologies for not posting our Mother's Day message. Here is...
Easter Message
Message preached Easter Sunday Morning 2014.
Parable in a Picture
The ever energetic and gifted David Garibaldi paints a parable. Even when you cannot see Him He is there…....
"When all is forgiven, there is nothing to hide, …and where there is nothing to hide, …there is nothing...
Life in the Spirit – Romans 8:1-17
This message was preached as part of a series on Romans by Pastor Paul Woodburn
Sin the Law and I – Romans 7
This sermon was preached as part of a series on Romans by Pastor Paul Woodburn
Welcome to the Woodpile!
It looks like we are moments away from launching our latest website! Join us in praying that this will...
Peace with God
Pastor Paul Woodburn Series on Romans


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Days after the Cleveland Browns shocked the NFL world by trading away former third overall pick, Trent Richardson, in the 2012 draft to the Indianapolis Colts. Reports are surfacing that the Browns are looking to rid of WR Josh Gordon. Gordon was drafted in the second round of the supplemental draft by the Browns because he is that talented. Standing at 6'3″ and 225 pounds, Gordon has the height and speed to be a very good WR in the NFL. His development is slowed do to the current quarterback situation in Cleveland and his lack of competitive college experience. Apparently the Browns want to rid of Gordon for two reasons. Reason one being that they think they can get a 2nd round pick in return for him and reason two being that coaches and management do not like his attitude. He finished last season with 50 catches, 805 receiving yards and 5 touchdowns.
Adam Schefter and Adam Caplan reported this earlier today-
With that being said let's look at the pro's and con's of acquiring Josh Gordon.
Financially the Eagles are in a pretty stable position right now. Gordon doesn't have a huge tag because he is still in his rookie deal worth 4 years 5.3 million dollars, signed on July 16 2012. So he would have two more years after this season under team control.
His on field impact would be enormous compared to what the Eagles are currently getting out of Riley Cooper. Gordon is the same size but is stronger and faster than Cooper and he can create separation against the corner which Cooper hasn't shown the ability to do.
Thursdays game against the Chiefs showed Eagles fans how much of an impact not having Maclin will have on this offense. As I just stated above, Cooper isn't anything more than just a red-zone target right now until he proves otherwise. Since Maclin has an ACL tear and is out for the season the Eagles do not know if he will be able to fully recover and if they will resign him. This was Maclin's contract year so if they do bring him back at what price will it be?
It is said that the asking price for Gordon will be a 2nd round pick. For the Eagles this is a tougher deal to make because they can't afford to lose picks with how many holes they need to fill on defense. The Eagles need these picks to sure up every secondary position, nose tackle, and quite possibly (probably) the quarterback spot.
Does the risk out weigh the reward here? Some would say yes and other will say no but one thing is for sure, this Kid has potential to be very good and the Eagles could use him this year.


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3.04pm Tuesday 24th November 2009
Villagers in St Nicholas had a rude awakening yesterday (Monday) morning as the village was engulfed with with floodwater running off the surrounding fields.
Village swamped by early morning floods
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When a control's Visible property is set to False, no clever CSS tricks are performed: The control simply doesn't generate any HTML. This documentation is archived and is not being maintained. For details, see Developing a Composite Control. So, for instance, to add a new ListBox to a page, you should just need this code: Dim lst As New ListBox Me.Controls.Add(lst) The problem is that, with this code, the have a peek here
Code: Adding Controls at Run Time (Visual C#) Visual Studio .NET 2003 This example adds a text box and button to a Web Forms page at run time. Change how my Fields render4. The container for the controls is a PlaceHolder Web server control named Placeholder1. ASP.NET AJAX Collapsable Panel Extender9. https://msdn.microsoft.com/en-us/library/kyt0fzt1.aspx
Retrieve Values From Server Side AJAX Controls34. Model Binding Part 3 - Updating5. If you insert controls dynamically and then reinsert them during a round trip, but with different values. ASP.NET AJAX PasswordStrength Extender16.
The handler creates as many label controls as the user has selected from the drop-down list. Table Free Templated Controls3. Recommended Version This documentation is archived and is not being maintained. Learning resources Microsoft Virtual Academy Channel 9 MSDN Magazine Community Forums Blogs Codeplex Support Self support Programs BizSpark (for startups) Microsoft Imagine (for students) United States (English) Newsletter Privacy & cookies
Security User input in a Web Forms page can include potentially malicious client script. At runtime, when you want these controls to be added to the page, just set their Visible property back to True. Create XML Documents from SQL Data7. Create a New Custom ExtenderASP.NET AJAX1.
Developer Network Developer Network Developer Sign in MSDN subscriptions Get tools Downloads Visual Studio Subscription access SDKs Trial software Free downloads Office resources SharePoint Server 2013 resources SQL Server 2014 Express Not the answer you're looking for? Is it possible to change a C++ object's class after instantiation? For details about page stages, see ASP.NET Page Life Cycle Overview.
Two Simple Techniques for Triggering Updates to Update Panels35. http://stackoverflow.com/questions/581286/adding-controls-in-runtime-problem-asp-net ASP Forms Login Relocation5. More Structured Query Language7. Creating a Site with IIS7 Manager6.
Configure the ASP.NET AJAX Calendar Control21. navigate here The html attribute OnClick is a client side, when a user clicks on the button it fires a piece of JavaScript The server event OnClick happens when a user clicks a Is this page helpful?YesNoIs this page helpful? ASP.NET AJAX ModalPopup Extender Control6.
ASP.NET AJAX ListSearch Extender26. Between different user accounts, which folders are "shared" and which are personal? Tailspin Spyworks - Display Shopping Cart10. http://digitalproduk.com/add-control/add-control-at-runtime-asp-net.html If it is check for postbacks.
DataPager ControlVisual Studio Designer1. whenever they are opening webforms means that control should avail for the user. You'll need to retrieve the Content control you want to add your ListBox to from the Page's Controls collection by position -- and you'll have to drill down through several levels
There're quite a few good articles about working with dynamically created controls. Also to fully understand what the problem is, it's neccessary to familiarize yourself with the page lifecycle. Snippets IntelliSenseAjax Control Toolkit1. Build a Custom ASP.NET AJAX Server Control23.
LINQ to SQL: Data Model3. What is a Database2. Hidden Field Divs5. this contact form Code Optimized Profile2.
You'll be auto redirected in 1 second. asked 3 years ago viewed 19949 times active 1 year ago Blog Stack Overflow Podcast #97 - Where did you get that hat?! Reply ramiramilu All-Star 78971 Points 16382 Posts Re: User can create controls at runtime. Dynamic MetadataASP.NET 4.51.
In order to programmatically add a control to a page, there must be a container for the new control. Insert filename in external-command Clue 18 - Should this be on Stack Overflow? Set Up Your Development Environment for ASP.NET 3.541. Code Search View Hierarchy3.
Discover Application Changes Prior to Deployment23. May 25, 2013 09:39 AM|aspnet2sams|LINK Shanmugapriya Nadimuthu For that the client requirement is, in the same webform itself there should be one add button is there May my understanding of the NumericUpDown Extender Control28. The risk in compilation of snippets from aspnet2sams is at post made by person.
Write Code More Quickly with Unit Tests15. snippets are to show the path for getting the job done particular to thread. Redmond August 14-18, 2017 Redmond, WA .NET InsightSign up for our newsletter. Get Started with LINQ2.
Because you do not know how many items will be returned, you want to dynamically generate one table row for each returned item. myLabel.Text = "Label" + i.ToString(); myLabel.ID = "Label" + i.ToString(); PlaceHolder1.Controls.Add(myLabel); // Add a spacer in the form of an HTML
element. For instance, if you're adding or removing controls based on the user's security role, the LoginView is a simpler solution.


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When your plate begins to overflow it is time to say enough and take a blogging break. At least that is the wisdom I am hearing from my Father's whispers--must heed and step away for a time.
That does not mean that I won't be checking in on my favorite blog sites :)
Hope to see you all soon :)
50 Frugal Summer Fun Ideas
2 days ago


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Monday, October 1, 2012
For Gimondi & Bianchi Fans: Bianchi Oltre XR "Gimondi 70"
The Oltre XR "Gimondi 70", with Campagnolo's Super Record EPS electronic gruppo , has four customized components with the "Gimondi 70" :
- Campagnolo Bora high-profile carbon wheelset (with Veloflex tubolars)
- Selle San Marco Concor carbon FX saddle
- La Spirale white grip
- Elite Corsa bottle
The graphics on the "Gimondi 70" feature personalized graphics: the mix of "celeste" Bianchi and light blue color, the latter referring to the Bianchi jersey worn by Gimondi and the sapphire, the amulet stone distinguishing the people born in September; the names of Gimondi's main wins, multicolor inserts along the tubes to remind all of the prestigious Felice's wins: Tour, Giro, Vuelta, World and Italian Championships; a Bianchi logo like the one on Gimondi's bike 40 years ago.
Stories for the Italian Cycling Journal about rides, granfondos, touring, having a good time cycling in Italy, Italian cycling history, racing, etc. are always welcome.
Follow on Twitter: ITALIANCYCJOURN
Contact me at email@example.com. There are more than 2,600 stories in this blog. The search feature to the right works best for finding subjects in the blog. There is also a translate button at the bottom so you can translate each page.
Subscribe to: Post Comments (Atom)


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Create amazing presentations for free in just a few minutes and turn your ideas into stunning live stories!
Emaze is a startup elearning tool build entirely on html5 is the new way to create presentations that turn your ideas into stunning live stories! . For example, users can't choose any color they wish for text, or any transition between slides. This is because these are limited by Emaze to best fit the chosen template. Templates, by the way, are a key feature the founders tout as aimed at delivering a high-quality visual impact. There are currently six templates, including 2D and 3D ones.
In conclusion Emaze is a startup eLearning tool between microsoft power point and prezi .


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Ashland residents are illegally downloading more movies, TV shows and music — even though they face huge fines and a crackdown by media companies intent on protecting their material.
Working on behalf of movie studio clients, the U.S. Copyright Group, or USCG, sued tens of thousands of people last year for downloading films such as "The Hurt Locker." It has cases pending this year.
Violators face fines of up to $150,000 for each illegal download, although the USCG usually tries to get each offender to pay a few thousand dollars to settle the lawsuit out of court.
The city government-owned Ashland Fiber Network, Charter Communications, Qwest and other telecommunications providers receive a notice when one of their customers has allegedly violated a copyright. AFN's policy is to pass news of the notice on to customers, and to ask people to check a box acknowledging they have allegedly violated AFN's service terms. They also acknowledge that future violations may result in termination of Internet service, said AFN Network Administrator Chad Sobotka.
Customers can send comments to AFN. Some have blamed roommates for illegal downloads, while others said they had wireless Internet at home and hadn't secured it against neighbors with a password. A few have been angry at AFN for sending notices, Sobotka said.
Copyright infringement in Ashland is widespread — and growing.
AFN sent out 54 copyright infringement notices in 2006. Numbers have been skyrocketing since then, with 657 notices sent out in 2010.
While media companies are becoming more aggressive about protecting their products, programs such as BitTorrent have made mass theft and swapping of copyrighted material easy.
Sobotka said parents might not be familiar with the file-sharing programs, but many high schoolers and college students are adept at using them.
Sobotka said a father called him because his high school-age son had received a copyright infringement notice.
"He and his wife were freaking out," Sobotka said. "I had to explain about file-sharing."
Programs such as BitTorrent allow Internet users to band together into swarms of people, who are all downloading and uploading content, such as movies. The swarms can have thousands of users and be international in scope, said Ashland Information Technology Director Rob Lloyd.
"For illegal downloads, the swarms are also its weakness," Lloyd said about BitTorrent and similar programs that are known as peer-to-peer, or P2P, networking services.
Copyright holders monitor the swarms and then send out copyright violation notices to Internet service providers, Lloyd said.
Movie studios are even participating in the swarms by sending out dummy movie files. Then they capture the Internet Protocol addresses of people who are attracted to the bait, Sobotka said.
An Internet Protocol address is the individual number assigned to each computer using the Internet — a bit like a human's Social Security number.
"Most people think their activities are anonymous on the Internet," Sobotka said. "Young people need to know that they can very easily be monitored."
At Southern Oregon University, Coordinator of Student Conduct Casey Clithero said there has been an increase in the number of students running into copyright trouble — possibly because of growing enforcement by copyright holders.
For the previous three school years, he met with four or five students annually about copyright violations.
"This year alone, I've seen nine through the fall term and the first part of winter term," Clithero said.
Warner Bros. has been most active in going after SOU students this year, he said.
The Higher Education Opportunity Act shields SOU from having to reveal their names, but students who engage in illegal downloading do have to have an interview with Clithero.
He emphasizes to them that they could be saddled with hefty legal fines. The students are blocked from being able to log on to SOU's Internet network until they purge the illegal material from their personal computers, Clithero said.
"A lot of them know that they're not supposed to do it, but it's second nature. They can point and click and have something," he said. "They wonder why it's an issue. I've had students say, 'I don't know why it's a big deal. Everyone's doing it.' I tell them, 'If you have friends who are doing it, I suggest you share your experience with them.' "
Clithero added, "I've never had the same person come through twice."
Copyright holders are usually satisfied if a student removes illegal downloads, but a student could become the subject of a lawsuit if the company wants to pursue the issue, warned SOU Network Communications Service Manager David Whipp.
Boston student Joel Tenenbaum has become the poster child for what can go wrong when someone illegally downloads material.
In 2003, Tenenbaum received a copyright infringement notice for downloading songs, with a demand that he pay $3,500 to settle the case. He offered $500, which was rejected, and he landed in court, according to the website he launched to chronicle his travails.
In 2009, a jury returned a verdict against Tenenbaum and awarded $675,000 in damages to several record companies. A judge later reduced that to $67,500.
Tenenbaum has appealed, saying that amount is still excessive, while record companies are arguing the penalty is too light.
Whipp said people who use BitTorrent and other programs to download material unwittingly open their computers to everyone — and become providers of the copyrighted material.
"It's a default setting. It starts sharing from your computer to the rest of the world," he said. "That's where students are surprised."
For students or any other residents who wonder whether they are illegally downloading copyrighted material, Whipp offered a simple rule-of-thumb.
"If you're getting something you would normally expect to have to rent or pay for, that's a red flag. When it comes to movies and music, it's most likely copyrighted and therefore you're putting yourself at risk," he said.
Staff writer Vickie Aldous can be reached at email@example.com or 541-479-8199.
Illegal downloading skyrockets in Ashland
Ashland residents are illegally downloading more movies, TV shows and music — even though they face huge fines and a crackdown by media companies intent on protecting their material.


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Find $\displaystyle y_1(x), y_2(x)$ so that $\displaystyle J$ is minimized.
$\displaystyle J(y_1,y_2)=\int_0^\frac{\pi}{4}(4y_1^2+y_2^2+y_1'y _2')dx$
$\displaystyle y_1(0)=1, y_2(0)=0$
$\displaystyle y_1(\frac{\pi}{4})=0, y_2(\frac{\pi}{4})=1 $
My work so far
I set up the Euler-Lagrange equation for each of the functions, giving me a set of second order differential equations:
$\displaystyle y_1''=2y_2$
$\displaystyle y_2''=8y_1$
I tried putting the equations in matrix form and using Wolfram to calculate the eigenvalues and eigenvectors. But solving a 4x4 system with complex eigenvalues seems to be beyond the scope of my calculus of variations course. I suspect there is a simpler way to do it, something that can be done by hand.
According to my textbook, a first integral of a Lagrangian of several functions, not explicitly dependent on $\displaystyle x$, is given by:
$\displaystyle L-\sum_{i=0}^{n}y_i'L_{y_{i}^{'}} = C$
Using that property I obtained another equation:
$\displaystyle 4y_1^2+y_2^2-y_{1}^{'}y_{2}^{'}=C$
I'm not sure what to do with this though. So basically I'm stuck.
Any help is appreciated!


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Gameweek 16 preview
December 11, 2014
13 Dec 15:00 Burnley v Southampton
13 Dec 15:00 Chelsea v Hull
13 Dec 15:00 Crystal Palace v Stoke
13 Dec 15:00 Leicester v Man City
13 Dec 15:00 Sunderland v West Ham
13 Dec 15:00 West Brom v Aston Villa
13 Dec 17:30 Arsenal v Newcastle
14 Dec 13:30 Man Utd v Liverpool
14 Dec 16:00 Swansea v Spurs
15 Dec 20:00 Everton v QPR
Only one place to start (and finish as it turns out) – and that's who are the majority of us going to replace Sergio Aguero with? He's due back from injury on the 10th January. That's five gameweeks away – way too long to leave him resting on your bench.
Best place to start looking is in amongst his City team mates. City's favourable run of fixtures in to the New Year starts with an away trip to Leicester – so goals pretty much guaranteed. Although the best options may lie in City's midfield with David Silva back in contention, Samir Nasri in amongst the goals in their Champions League victory in midweek and Yaya Toure finally in a run of form. One of Edin Dzeko or Stevan Jovetic will start this weekend, but there's little guarantee either will cement the attacking berth – and both have just returned from injury. Dzeko managed to complete most of the Roma tie before being replaced by Jovetic. Neither scored.
The choices away from the City team would all allow for a more expensive investment in the midfield. Only Diego Costa, Wayne Rooney and Robin Van Persie look like worthwhile investments in a similar price range to Aguero. Much more in form are those lower mid price options that have dominated the striker standings since day one. West Ham have an abundance of options. Only Chelsea and City have outscored the Hammers, and for the first time in their 642 year history they have what is commonly referred to as a selection headache. Andy Carroll should get a start based on his high scoring performance of last week. Enner Valencia could miss out having been replaced by Diafra Sakho, who went on to score the last goal of their three against Swansea.
With seven in nine, Wilfried Bony would also free up a hefty four million for spends elsewhere. Swansea remain in the top half and have a manageable run of fixtures through Christmas. Also in the £8-9 million club is Graziano Pelle, who ended his barren run with a goal last week against Manchester United. Southampton's run of fixtures from hell takes a welcome break this week with a trip to Burnley, so their may be a respite for those owning Saints players. They may get in among the points again. Having kept four consecutive clean sheets, it's now four without a shut-out. Clyne, Bertrand and Forster may get the points they need to keep them top of their respective positional standings.
There are always options in the Chelsea team. Their defeat last week will probably be no more than a blip. They look the best option for a captain choice taking on Hull at Home. This inevitably means Eden Hazard will be in among the points, probably scoring one and assisting another by Costa.


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Yükleyen: Şehir Rehberi
Yüklenme Tarihi: 05 Ocak 2015 - 22:10
Strolling through the Old Quarter of Hanoi, Vietnam, in the evening is a pure delight, especially after a light rain has wet the streets to provide a glistening reflection of the lights from the many restaurants, shops and bars open late. We visit the weekend Night Market, and consider how the economy of Vietnam is doing relatively well.
Etiketler: hanoi, vietnam, travel, guide, gezi rehberi


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It's not all the time that you discover you need a replacement Distributor Cap to fix your automobile. Your GMC dealership isn't the only place to locate the best parts to repair your T15. You bought your T15 because its reliability and longevity struck a chord inside you; so why would you settle for second rate when it comes to superior quality auto parts? While it's not hard to locate replacement parts for GMC vehicles, these days the necessity for nothing but the absolute best are required to maintain your car or truck.
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Five Facts
Gerald Tebben
Gerald Tebben, a Coin World columnist for more than 30 years, also contributes to Coin World's Coin Values and edits the Central States Numismatic Society's journal, The Centinel. He collects coins that tell stories.
Coin World's bloggers are not edited by Coin World's editorial staff and blog posts reflect the views of the individual author.Visit one of our other blogs:
Stanley Kowalski's coin
With a mintage of slightly more than 400 pieces, the 1879 Flowing Hair Stella is the most common $4 gold piece.
Stellas, or $4 gold pieces, were produced nearly three fourths of a century before Stanley and Stella took up residence in the French Quarter, and none were produced in New Orleans.
In the 1870s, John A. Kasson had a history, a title to be reckoned with, and a plan. He had served six terms as a congressman representing southwest Iowa before deciding not to run again in 1876. Among other duties while serving in congress, he was chairman of the House Committee of Coinage, Weights, and Measures. After leaving Congress, President Rutherford B. Hayes appointed him Envoy Extraordinary and Minister Plenipotentiary to Austria-Hungary.
What the world needs now, Kasson told his boss, Secretary of State William Maxwell Evarts, is an international gold coin, one that would flow easily from nation to nation. Convertibility was big in Europe, with the Austrian 8 florin, Dutch 8 florin, French 20 franc, Italian 20 lire and Spanish 20 peseta coins all being equal in value.
The House coinage committee signed on, designating the new international coin a Stella.
While the foreign coins were worth $3.88 U.S., the United States never tried to match the European coins exactly. Instead, it opted for a $4 coin, which proved not close enough for a cigar.
The Stella showed Liberty on the obverse surrounded by 13 stars separating each letter of the legend 6G .3S .7C 7GRAMS, giving its metallic content as 6 grams of gold, 0.3 grams of silver and 0.7 grams of copper. A large star dominated the reverse center.
Charles E. Barber and George T. Morgan both took a crack at Liberty on the obverse. Barber's showed Liberty with flowing hair. Morgan's had coiled hair. Both types were struck in 1879 and 1880, but most bore Barber's flowing hair design and the date 1879.
In 1879, the Mint made up 15 sets of three pattern coins – a silver dollar, a patented gold alloy dollar and a gold Flowing Hair Stella – for coinage committee review. Congressmen were invited purchase the coins at $6.50 a set. The sets proved so popular that the Mint struck about 400 more. Unsold sets were offered to connected collectors in subsequent years for $15 a set.
A Guide Book of United States Coins (the Red Book) estimates mintages of 425 for the 1879 Flowing Hair coin, 10 for the 1879 Coiled Hair version, 15 for the 1880 Flowing Hair delicacy and 10 for the 1880 Coiled Hair coin.
As patterns go, the 1879 Flowing Hair Stella is fairly common. Few people collect patterns, and mintages are frequently in the single digits. But because no other $4 coins were struck, and because the Stella has been listed in the Red Book since the beginning, it is collected (at least conceptually) as part of the regular-issue gold series. At auction the most common Stella usually trades north of $100,000.


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Yesterday afternoon, a colleague took me out for a late lunch. She wanted to do something to show appreciation for how much I had helped her during the great syllabus project of late September. She had been in a place with limited Internet access while she helped aging family members. I did most of the syllabus work for her.
I told her that a simple thank you was enough, but she continued to ask me to let her buy me lunch. And so, I did. Sometimes it's good to let people return a favor.
As we walked to lunch, she asked me what I was working on in terms of my writing. I told her that I was transforming blog posts into a book of essays that explores how one woman tries to live an authentic life even as the values of one place, like work, conflict with another, like church. I joked, "It's going to be like Eat, Pray, Love, but with a more solid theological grounding."
My colleague has solid theological grounding herself, although we come from different Christian traditions. We talked about the need for books that explore the idea of authenticity. We talked about the need for grounding. She even prayed over me/with me about the project.
I must confess it was not a typical lunch with colleagues. But I found it nourishing nonetheless.
She prays in public much more differently than I do, when I remember to pray at all. She talks to God like God is sitting there eating garlic rolls with us. She asked God to be my PR agent, to find me the best deal for my book, the one that would let my important words be spread far and wide.
And she prayed for the other books that she knows that I will write.
Our late lunch made me think of all the ways that the world sends us validation. I worry that I've taken too long with this project. I think about the inner wisdom that I got 2 years ago, the experience where I heard clearly, "Get that memoir written," not "Go to seminary" (for more on that experience, see this blog post).
I've been feeling a bit of despair because here it is 2 years later, and though I still feel the urgency, I'm not done yet. I've worried that I've blown it somehow, lost a chance. It was good to be reminded that there is still hope.
I have other friends who also function as believing mirrors, as cheerleaders, as people who prod me to go in the direction I should go. But what was interesting about yesterday is that this colleague did the same thing, but in a different way. She said, "Have you asked Jesus for what you need?"
Actually, no I haven't--and for much the same reason that I offered when she asked me if I would self-publish. I am not good at self-promotion. I am not good at asking for what I need. I know that God has more important priorities than my writing life.
I also realize the fallacy of these thoughts. Is my God really so limited? Surely God can find time for our issues, in addition to the bigger issues of Ebola and war and trafficking and all those other injustices that we heap on each other.
By now, some of you might be saying, "Don't you have a theology blog for these reflections?" It's interesting to me how I feel strange about discussing the idea of prayer and creativity and God over here at this blog.
At one point, my colleague talked about the prayers that we offer before we start on our work. I confess that I did not confess that I don't often pray before I start on my writing tasks and other creative work.
What might happen if I did?
I thought my colleague was returning a favor with a simple lunch together; I didn't realize that I'd get so many blessings in return.
Best Essay Collections of 2017 by Women Authors
5 months ago


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Rumor: Jay Bruce headed to AAA
I just was emailed that Jay Bruce is headed to AAA. I don't know when or how soon and haven't verified this yet, but it's something I was told and thought I'd pass it on.
UPDATE: My source said he assumed it was effective today, but I haven't been able to confirm it with anyone else yet.
UPDATE II: As Doug said in the comments, it's official.
Following the game, Bruce was promoted to Triple-A Louisville to help plug short-term concerns with the Bats. Earlier this week, shortstop Paul Janish was called up to Louisville.
Lookouts manager Jayhawk Owens expects Bruce and Janish, two of Cincinnati's top 10 prospects, back within a week.
UPDATE III: (7/13) From the Enquirer:
The Reds sent top prospect Jay Bruce to Triple-A Louisville.
It's likely to be a temporary move. Dewayne Wise is on the DL with a hamstring injury.
What happens if Bruce is hitting .400 when Wise is healthy?
"We'll have a decision to make," player development director Terry Reynolds said.
I've been a Reds fan since the late '60's, with my luck of being able to attend plenty of games at Riverfront during the BRM era. I was sitting in the Green Seats in the OF when Pete came home in '84 and was in the Red seats when Glenn Braggs reached over the fence in '90 to beat the Pirates. I have had many favorites from Jim Maloney to Johnny Bench, Barry Larkin, Adam Dunn, and Jay Bruce.
Join the conversation! 21 Comments
I want him to get some ABs in the MLB sometime before the season is over
This move indicates that he will get a September callup, with a chance for meaningful at bats if any of our outfielders are traded. He would really have to suck for it not to happen.
This move – if made – may also indicate that a trade of a major-league outfielder is near at hand, opening a vacancy that will need to be filled sooner rather than later.
Or that the Reds believe that Norris Hopper is the short term answer in the OF…yikes!
Wow. Im not sure how I feel about this really. The kid has unreal talent, I have no doubt about that. I am just curious as to whether they beleive he is actually ready for AAA vs they need him soon.
Yes, it was a small sample size, but he really didn't seem to have any trouble with AA pitching. As risk averse as Krivsky has been about player promotions and jumping levels, I seriously doubt they'd jeopardize his future because of a perceived need.
Something I've been wondering a while, but haven't posted my thoughts. At some point, does a minor leaguer "get it" put all their skills & talent together such that they could hit (or pitch) in the majors if given a chance.
We've seen the #1 overall picks like Griffey and A-Rod ging seemingly straight from high school to the majors. But Josh Hamilton this year going from A-ball, to 5 years out of baseball, to major league starter is what really got me thinking about this. Is the talent there for others to skip levels like that if given the opportunity?
The year Dunn broke through…he skipped high-A, started in AA and played over a third of a year in Cincinnati.
When we see the rapid promotion, we see it more often with the 1st round college draftees like Ryan Zimmerman or Tim Lincecum. But I think that there are some high school kids who are just as talented, that can and should make a rapid progression through an organization. I think we may be witnessing that with Bruce.
Oh, I don't think Jay isn't ready for AAA. I think he will handle himself just fine there, I was just under the idea from things I had read all year that Jay Bruce was on the 'Homer Bailey' plan of half a season in Sarasota and half a season in Chattanooga.
I don't think a promotion to AAA will hurt Jays future at all, just that maybe they are making the move sooner than they had planned becuase of how chips are falling in Cincinnati.
Yeah, I think this probably has more to do with getting him ready for the big leagues after a trade of a staring outfielder.
This is pretty interesting. I know we were discussing "adjustments" the other day, and wondering how Jay would react to the league reacting to him. I guess that gets short-circuited.
There's no reason he can't do that at the AAA level, but it's definitely a break from precedent in the Krivsky era.
GregD, I've been interested in that point you made. A couple weeks ago, Will Carroll alluded to an article (and now I can't find it) that apparently said that – at least with pitchers – once a guy can contribute to the big league team, he should be promoted and asked to do so. I'm guessing it has something to do with injury rates and the fact that many pitchers actually peak at 22-24, not 27-28.
Well I guess we will find out in about 6 hours when AA and AAA start their games.
It is official.
From the Chattanooga Times Free Press today.
Following the game, Bruce was promoted to Triple-A Louisville to help plug short-term concerns with the Bats. Earlier this week, shortstop Paul Janish was called up to Louisville.
Lookouts manager Jayhawk Owens expects Bruce and Janish, two of Cincinnati's top 10 prospects, back within a week.
If they were going to move someone for a week, I wouldn't think it would be Bruce…do you?
Im with you Bill…. I said on my site that I think if he hits, which I expect him to do, that I would bet he stays there.
off subject…but for those Reds fans that don't live in the greater cincinnati area (like myself) Directv is showing a free preview of the extra innings package starting today…i'm assuming that goes for all other cable companies as well (time warner, comcast, etc.) it goes through the 18th
Oh man, thanks for the heads up Twill.
Greg, I think the holdup for a lot of young guys is that they just aren't physically ready to play major league ball. The NFL requires guys to be at least (uh, what is it, 2 years?) removed from high school because they aren't big enough. Guys just coming out of high school are still growing.
no reason they shouldn't keep him there, but when dewayne wise comes back, he'll be gone. once again, wise is taking up a roster spot someone better should have. 🙄
I'm not sure about the "physically ready" thing, Justin. Have you seen Jay Bruce? He's as big as anybody.
Or more to the point, think about David Eckstein – he still doen't look "ready," from a physical standpoint.
Decent debut so far.
1-3 with a HR. one of his outs was a line drive to the right fielder.
Oh, and he just gunned a runner out at home plate to end the 6th inning.
I went to the Bats game last night and Jay looked good. His HR was a shot and his gun was awesome. He also had a nice shot to the rightfielder, a groundout, and a strikeout. All in all it was a very nice debut. Janish looked alright. He had 1 walk, 1 bloop hit, but had an error. Homer looked terrible though. He couldn't locate his fastball and that was basically all he threw the entire game.
Chris — I'm not saying Jay Bruce (or anyone specifically) isn't ready. But high school grads in general, a lot of them aren't going to be.
Comments are closed.


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05 October 2012 8:03 AM
I'm Awesome? Ohh, its just a big lie. I'm not awesome actually, but I'm try to comfort myself. People keep hurting me even I try to make them happy. People come and then go. That's my life. You know how actually its feel? Suck bruh, suck. If you approach me just to make me hurt, then you should die. You don't even deserve for me. I try to find my happiness, but until now I can't find it. Maybe I will find it in Jannah, Insya-Allah. Keep smiling, this is the only way you can kill your enemies. They can't even see you smiling for a second, because they just too envy with your kindness, beautiful and etc. Now I feel really awesome.


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Saad Khan is an Independent documentary filmmaker. His first film Chuppan Chupai | Hide and Seek (2013) follows lives of four transgender and gay Pakistanis. His second documentary Zunn: showgirls of Pakistan (2016) deals with dancing girls, seedy theaters and low-brow entertainment in villages and towns of Pakistan.
Dr. Rahul K. Gairola (PhD in English Literature and Theory & Criticism at the University of Washington, Seattle) specializes in postcolonial, diaspora, and transnational studies; critical theory; South Asian studies; comparative American studies; digital cultural studies; and women's, gender, and sexuality studies.
In the Q&A, Dr. Rahul Gairola and Saad Khan talk about sexuality and gender in post-colonial South Asia in light of Chuppan Chupai's subjects. A discourse on Article 377 i.e. The Anti Homosexuality law in India and Pakistan originally introduced in 1860 under the colonial rule of the British Raj. Mr. Khan also discusses the problems faced in making both his documentaries and the process of guerilla filmmaking in Pakistan.
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I wonder how many times I have thought to myself I hate living like this. This same old routine going to school, going to work, going to the same church that I grew up in, living in the same place i've lived in for 23 years, not being able to really take control and do anything except do the necessities and then go home. I'm basically a hermit b/c I don't have a driver's license no one wants to drive all the way up the mountain save a select few and it's really discouraging at times. I wonder why and wish I was back in harrisonburg but when I was in harrisonburg I wished I was in roanoke b/c some of my friends were in roanoke I guess you can't have your friends and your independence too. Part of me wants to move away to a new city where they have fabulous public transportation so i can have my independence and meet cool people and then get a great job and love life again. To help me get out of my rut I'm going to get a haircut something different I'm tired of getting a haircut and no one noticing. But the God says there is a season for every event under heaven so I guess that includes this too. I have till this summer before I get my associates in culinary arts and certificate in baking. Trusting on God's everlasting love i'll make it through everyday and maybe he'll even give me the desires of my heart that he's planted there 🙂 but only time will tell.
Stuck in a rut
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This is just unacceptable why leave your house like this? Girl create a shopping list you need some lip moisturizer for those lips, some make up for those eye and a cute little face lift. I'm not sure if aunty "I don't own a mirror" can fix this ratchet mess but I believe there is hope I mean look at lady gaga.
Innocent or Guilty?: Innocent, only guilty of not going to bed on time… EVER.
Sentence: This Ratchetness is sentence to daily lip moisture routines and to walk around with a plastic bag on her face in shame for 24 hours.


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We had gone for a weekend and must say we really enjoyed our stay. The food was very good and we as a family enjoyed spending time away from home. The villas were very comfortable and the view was nice. we would definitely go back.More
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Blood - nerve barrier characteristics of research
【Abstract】 The blood-ocular barrier with blood - aqueous
barrier, the blood - retinal barrier, these special structure on the prevention of eye injury in the process of inflammation
and immunity play an important role in the occurrence. To date, the blood - nerve barrier (blood-optic nerve barrier)
the concept of domestic and foreign textbooks, almost no description, this article on the blood - nerve barrier
characteristics of the study were reviewed.
Key words blood - nerve barrier of blood - the blood-ocular
barrier - brain barrier
Research development of blood-optic nerve barrier
* KEYWORDS: blood-optic nerve barrier, blood-ocular
barrier, blood-brain barrier
0 Introduction
The eye is an organ immune privilege, there are several factors to maintain the special nature of the eye structure and function play a role, the most important is the blood-
ocular barrier [1]. It can be useful for selective blood
filtration material, in order to maintain a stable environment within the eye. When the barriers are harmful factors can affect its function during invasion, resulting in metabolic disorders, resulting in the occurrence of eye disease. Currently accepted blood-ocular barrier with blood - aqueous
barrier, the blood - retinal barrier, these special structures on the prevention of eye injury in the process of inflammation and immunity play an important role in the occurrence. But so
far, right blood - nerve barrier (blood-optic nerve barrier)
was highly controversial. Domestic and foreign textbooks, yet the concept. This article on the blood - nerve barrier
characteristics of the study were reviewed.
One blood - nerve barrier properties
1963, Rodriquez-peralta [2] with 2-amino acridine dye
injection method to observe the blood - nerve barrier
characteristics of the situation. It was found that intravenous injection of 2-Amino-acridine appears in the optic
nerve dura mater, but in the subarachnoid space and
cerebrospinal fluid does not appear; in dural blood vessels, while in the soft meninges and blood vessels within the optic nerve does not appear; in choroid, sclera , Kuhnt tissue appears in the optic nerve did not appear. That the blood
between the blood and optic nerve - optic nerve barrier
properties. Barrier structure may be based on the optic nerve and pia mater capillary endothelial cells and their tight junctions.
Two characteristics of the optic nerve
Incoming visual information hub of the optic nerve is the only way is to treat the road from the optic nerve to the optic chiasm section. By retinal ganglion cells sent axons fiber drops, the histology of optic nerve and brain parenchyma in the white matter or spinal cord similar to the white
matter. After the sieve surface, there is no Schwann optic nerve membrane, but there is myelin sheath. The optic nerve in the embryonic development of brain sticking out between the time of the formation of part of the course, as the device.
There are 3 layers of optic nerve sheath, respectively, with the three-phase continuous layer of meninges. Inner layer of pia mater, the middle of the arachnoid, outer layer of dura mater. Optic nerve mainly consists of 4 above. (1) of the ball
within a paragraph. (2) orbit segment. (3) The tube segment. (4), intracranial segment. The paragraphs blood supply is extremely complex. Sieve plate anterior optic nerve fibers without myelin sheath, and retinal nerve fibers within the same transparent, and therefore smaller; the sieve plate and sieve plate area after the myelin sheath surrounding the optic nerve fibers there and therefore I increase the thicker in diameter. Therefore, the optic nerve is not an ordinary
peripheral nerve, but central nervous ahead of a prominent
nerve bundle.
3 on the blood - nerve barrier properties of the
Since the Rodriquez-peralta in 1963 pairs of blood - to
explore the characteristics of the optic nerve barrier since the domestic and foreign scholars of the in-depth study. In
1970 Machemer [3] with alkaline rhodamine B labeled protein, intravenous injection, observed in the optic nerve and surrounding connective tissue are stained intervals, while the optic nerve did not stain. That there exists between the blood
and optic nerve barrier properties. 1972, Peyman and Apple [4] with the electron microscope the distribution of horseradish peroxidase tracer was observed that there is no tracer into the optic nerve from the optic nerve capillary gap cavity.
They believe in the existence of blood-brain barrier
characteristics of the optic nerve. But their experiments did not mention whether the observed optic nerve head situation. Domestic scholars Yang Cun et al [5] that the blood vessels of the optic nerve with all the features of the central nervous system, blood vessels and performance of all of the peripheral capillary wall cells and surrounding cells, there is no gap between the endothelial cells and closely connected to the optic nerve microvascular bed is anatomically similar to the retina and central nervous system, blood vessels, and has self-regulation of physiological characteristics and blood-
brain barrier performance. Made with the blood vessels within the optic nerve - optic nerve barrier performance. The barrier
and the blood-brain barrier are very similar. The
choriocapillaris around the optic nerve head does not have this barrier function, allowing free passage of blood substances big pore wall. 1975, Grayson and laties [6] After intravenous administration of fluorescein sodium, fluorescent material was observed around the optic nerve to the optic nerve from the spread. That the optic nerve and the lack of a close connection between the choroid from a structural point of view is not a complete barrier to keep only the physical barrier function. 2001, Hofman et al [7] the use of advanced blood-brain barrier, non-blood-brain barrier-specific marker
of vascular permeability markers, combined with electron microscopy, pairs of optic nerve microvascular research. Found
that the former area of optic nerve head capillaries lack of
blood-brain barrier properties, a weak blood-brain barrier-
specific marker expression or no expression, endothelial cells were connected fenestrae-like cracks that contain many
pinocytotic vesicles on the part of the plasma proteins with a transparent sex. The sieve plate area, sieve with a blood-
brain barrier characteristics of the zone of capillary. Strong positive blood-brain barrier-specific marker expression,
endothelial cell fenestrae-like and were not linked with fewer pinocytotic vesicles. Domestic scholars Amy [8] that the optic nerve head blood supply from the two systems, from the central retinal artery is a non-permeability of blood vessels
associated with the choriocapillaris part of a certain
material can be dispersed. Therefore, the blood - nerve
barrier may belong to the blood - brain barrier part of the
4 blood - nerve barrier properties of research prospects
Based on the current findings, the general view that does exist between the blood and the blood in the optic nerve -
optic nerve barrier properties. Textbooks at home and abroad have not yet see the blood - the concept of the optic nerve
barrier. Barrier structure may be based on the optic nerve and
pia mater capillary endothelial cells and their tight junctions. Selective adoption of useful substances in the blood to maintain a relatively stable environment within the optic nerve. As for some of the small molecular weight tracer
extravasation, in order to sieve the former area of blood -
nerve barrier endothelial cell tight junctions between the bite was small with a small fracture sample, pinocytotic vesicles are more than just blood-brain barrier permeability
increased due. However, for larger molecules with a barrier.
"Immune privilege (Immune privilege)" The concept was first originated from the 19th century 70's, at that time, Doorremal found in the rabbit anterior chamber in certain human tumor cells can survive. The 20th century, 40 years,
Medawar was found planted in the anterior chamber of the graft can survive a long time. Later, people are increasingly recognized as the eye is an organ immune privilege claim. Eye immune privilege is involved and the maintenance of a variety
of factors, the most important thing is the blood-ocular
barrier, its meaning is to maintain the integrity of the organization to prevent the occurrence of autoimmune
inflammatory processes. Blood - the barrier characteristics of
the optic nerve blood-ocular barrier, as an important part of the same limiting effect of blood-borne immune cells and
molecules into the character. Compared with other parts of the blood vessels in normal physiological conditions, the dominant optic nerve complex vascular network has significant
restrictions on blood-borne cells and molecules into the eye of the characteristics of the organization. Thus, to some extent the immune response blocked outgoing access. Blood -
the optic nerve barrier characteristics of severely
restricting the blood-borne cells and molecules into the eye, while the blood flow in the immune effectors, including the sensitized T cells and antibodies were also largely outside of this barrier to the optic nerve.
Therefore, the blood - nerve barrier feature is the eyes,
one of the most important defense mechanism, its special defense capability and its associated mechanisms for the prevention and reduction of optic nerve inflammation, reducing trauma, inflammation, hypoxia and other damage of great
significance. In addition, the blood - nerve barrier
properties are still ophthalmic drug research that has practical value, although the eye there are many Chinese and Western medicine has been used clinically for many years, but these drugs in the effective concentration of the optic nerve is not easy detection, if the right blood - nerve barrier
Features an open and transparent mechanism for in-depth study
will provide clinical ophthalmology drug development and improve the treatment of optic nerve injury provide important
theoretical basis and experimental data. Therefore, the blood - nerve barrier properties to explore important. Reposted elsewhere in the paper for free download http://
The current response of blood - nerve barrier properties
of a deeper, more detailed, more comprehensive study. Such as observations What other unknown structures involved in the blood - nerve barrier function of the composition, which features induced adjustment factors. Optic neuropathy in order to deepen understanding of the mechanisms for the prevention and treatment of optic nerve lesions provide theoretical support.
5 affect the blood - nerve barrier factors
The researchers found that despite the eye of the environment is relatively very stable, but the blood-ocular
barrier by many factors, they can make the material through the blood-ocular barrier in the apparent rate of change. Similarly, the blood - nerve barrier properties as a blood-
ocular barrier is often an integral part of the subject to a
number of factors.
5.1 Blood - inflammation of the optic nerve barrier
properties and the present study shows that, resulting in blood - nerve barrier characteristics of the main factors is the inflammatory destruction of optic nerve injury [9]. The
study found that when malaria infection, optic neuropathy occurred in mice at the same time, along with the optic nerve axon and myelin sheath structure, such as nerve damage, glial cell morphology and distribution of abnormal mononuclear cells in the vascular endothelial proliferation. Description of these inflammatory changes and blood - nerve barrier
characteristics are intrinsic relevance. Moreover, the study also found that the blood - the optic nerve barrier
characteristics of neurological damage in mice before clinical
symptoms have occurred, indicating the optic nerve of vascular endothelial injury and brain injury has not synchronized, suggesting that the blood - the optic nerve than in the blood-
brain barrier properties barrier more easily destroyed as a
result of the inflammatory response [10].
5.2 Blood - nerve barrier properties and mechanical
trauma, or trauma can also cause blood pressure - the
destruction of the optic nerve barrier properties. The study found optic nerve trauma, and even the optic chiasm tumor
suppression, can result in blood - nerve barrier function
damage. Possible reason is that the injury has directly undermined the structure of the optic nerve, vascular endothelial damage, leading to blood - nerve barrier of the
direct damage, while chronic tumor growth, a longer period of oppression, invasion and secretion of inflammatory injury factor to the optic nerve occurs edema, further exacerbating the optic nerve and vascular endothelial damage, secondary cause of blood - the destruction of the optic nerve barrier [11], thus becoming the destructive effects of indirect optic nerve injury.
5.3 Blood - nerve barrier properties and MMP recent
studies [12] The metalloproteinases (matrixmetalloproteases, MMP) and blood - the relationship between the optic nerve barrier properties have been studied and found that when the blood - nerve barrier function destroyed, MMP-9 expression was
significantly lower that the MMP-9 and the maintenance of
blood - is closely related to the integrity of the optic nerve barrier. To prevent the use of MMP agent study further confirmed this point and found that application of MMP to prevent fluid MMP-1, -2, and -9 increased levels of TIMP-1 and
TIMP-2 levels decreased, thereby to improve the optic nerve
injury, blood - the optic nerve barrier properties to be protected [13].
5.4 Blood - nerve barrier properties and clinical drug hypertonic dehydration agents are commonly used IOP-lowering
drugs, a series of studies have shown that: A number of
intraocular pressure lowering drugs, as well as aldose reductase, sorbitol dehydrogenase, histamine, adenosine, substances such as anti-cholinesterase drugs have similar
effect. Can make the eye increased the concentration of other drugs, further research found that they can cause blood-ocular
barrier open. Similarly, hypoxia, inflammation of the state, can lead to blood - nerve barrier properties destroyed,
permeability increase. The study found that the inflammatory state, the optic nerve vascular endothelial permeability
increase, barriers will increase the pass rate of drugs [14].
1 Ferguson TA, Griffith TS.A vision of cell death: insights into immune privilege. Immunol Rev, 1997; 156:167-184
2 Rodriguez-Peralta, LA. The blood-optic nerve barrier. Anat
Rec, 1963; 145:277-287
3 Machemer R. Angiographic-histologic correlation of eye
vessel permeability with protein bound fluorescent dye. Am J Ophthalmol, 1970; 69:27-38
4 Peyman GA, Apple D. Peroxidase diffusion processes in the optic nerve. Arch Ophthalmol, 1972; 88:650-654
5 Yang Cun, Cao Mu-Rong, PENG Guang-Hua. Optic neuropathy.
1st edition. Zhengzhou: Henan Science and Technology Publishing House, 1996:5
6 Grayson MC, Laties AM. Ocular localization of sodium fluorescent: Effects of administration in rabbit and monkey. Arch Ophthalmol, 1971; 85:600-609
7 Hofman P, Hoyng P, vanderWerf F, Vrensen GF, Schlingemann RO. Lack of Blood-Brain Barrier properties in microvessels of the prelaminar optic nerve head. Invest Ophthalmol Vis Sci, 2001; 42 (5) :895-901
8 Amy. Ophthalmology book. 1st edition. Beijing: People's
Health Press, 1996:261
9 Pena JD, Agapova O, Gabelt BT, Levin LA, Lucarelli MJ, Kaufman PL, Hernandez MR. Increased Elastin Expression in Astrocytes of the Lamina Cribrosa in Response to Elevated Intraocular Pressure. Invest Ophthalmol Vis Sci, 2001;
10 Ma N, Madigan MC, Chan-Ling T, Hunt NH. Compromised blood-
nerve barrier, astrogliosis, and myelin disruption in optic nerves during fatal murine cerebral malaria. Glia, 1997; 19 (2) :135-151
11 Levin LA, Gragoudas ES, Lessell S. Endothelial cell loss in irradiated optic nerves. Ophthalmology, 2000; 107 (2) :370-
12 Ahmed Z, Dent RG, Leadbeater WE, Smith C, Berry M, Logan A. Matrix metalloproteases: degradation of the inhibitory environment of the transected optic nerve and the scar by regenerating axons. Mol Cell Neurosci, 2005; 28 (1): 64-78
13 Hughes PM, Wells GM, Perry VH, Brown MC, Miller KM. Comparison of matrix metalloproteinase expression during Wallerian degeneration in the central and peripheral nervous systems. Neuroscience, 2002; 113 (2) :273-287
14 Kiernan JA. Axonal and vascular changes following injury
to the rat's optic nerve. J Anat, 1985; 141:139-154 reposted
elsewhere in the paper for free download http://


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