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Contact Us
In 1986 The Theater Project purchased an important historical landmark as a facility to entertain and educate the members of this community well into the next millennium. Built in 1827, this building is located in the heart of downtown Brunswick, and continues to serve as an integral part of the community. The purchase of this beautifully preserved building has enabled The Theater Project to grow into a small but thriving year-round theater facility.
We are located at 14 School Street, right behind the Tontine Mall in downtown Brunswick.
Tickets can be purchased online from our Buy Tickets Page, over the phone using a credit card, or at the box office using cash, check, or credit card (Visa, Mastercard, Amex, or Discover).
**Please do not use the automated contact form to request tickets. Call (207) 729-8584 to make any reservations**
14 School Street
Brunswick, Maine
Tel (207) 729-8584
Fax (207) 729-0866
Email email@example.com


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Holiday Events 2017
Santa arrives in downtown on a fire truck traveling down Wenatchee Avenue on Saturday, December 2nd. At approximately 4:30pm, Santa will light the Community Christmas Tree in the Wenatchee Convention Center Plaza. Free photos with Santa inside the Convention Center until 6pm. Free photos, pizza, and crafts with Santa is Saturday, December 9th from 11am-2pm at the Wenatchee Convention Center. The final day of free photos with Santa is Sunday, December 10th from 11am-2pm.

subset: commoncrawl


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States of Matter Magazine Project
Lesson 8 of 15
Objective: SWBAT create a booklet that demonstrates their knowledge of the 3 states of matter.
Big Idea: Through this hands-on exploration of magazines, students will reinforce their knowledge of matter and its properties.
This lesson is a mini-project that can be sent home over a weekend or can be done in the classroom. I would give between 45-60 minutes to complete the task. The assignment uses the magazine booklet template and random magazines I have brought into school from home. If you don't have your own stash of magazines with pictures, have the students bring 1-2 each for added resources. They will each need minimum of 15 pictures for their project.
The Task
To introduce the project, I have the template on the SMARTBoard with the procedure. The students read along with me as I explain the project.
Students will use their knowledge of the states of matter to complete this project. They can also use their States of Matter foldable, made in a prior lesson, as a valuable resource for the project.
Students will go through the magazines and find 5 picture examples of each state of matter. They will glue the examples into the template pages and will provide a 1 sentence, short explanation for why that picture works as an example. They also need to sketch the molecules and describe their motion, as well as list facts about each state of matter.
This project addresses MS-PS1-1 as students are creating paper sketch models of each phase of matter.
If review of the states of matter are necessary in order to complete this project, students can play the following game, "vobackulary":


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After experiencing the loss of a baby due to miscarriage, many couples want to try to become pregnant again right away. It is important that you and your partner are physically and emotionally ready. If your body isn't ready for another pregnancy, you run the risk in repeating the miscarriage. Medically, two to three months is typically enough for your body to recover. It takes this much time for the uterus to recover and for the endometrial lining to become strong and healthy again.
Emotionally, you may need more time than this to come to terms with what has happened. A miscarriage can strain a marriage. It can cause feelings of grief, guilt, depression and fatigue. You may feel isolated and withdrawn. Make sure you work through these issues with your partner as well as a mental health professional if these feelings do not subside within a couple of months.
Once you have decided to conceive again, there are things you can do to prepare for another pregnancy. You should:
– Avoid unnecessary medication
– Take folic acid supplements
– Eat a healthy diet
– Exercise regularly
– Reduce or eliminate your caffeine intake
– Reduce or eliminate your alcohol intake
– Rest as much as possible
– Share your feelings with your partner and others
– Use stress-management techniques


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Forum News:
PRC 3.5 - Released!!!
PRC Links
PRC Manual
PRC Chat
PRC Contributors
Bioware PRC Group
PRC Downloads
PRC JavaCC 1.8
PRC Script Compiler
PRC GUI Add-on
Staff List
Player Resource Consortium
FAQ list
HOW TO: Make a 1st level PC with a PRC Class or Race
HOW TO: Casting Spells
HOW TO: Memorize Spells & Powers
HOW TO: Setting up the PRC on a Server
HOW TO: Setting up the ConvoCC on a server
HOW TO: Get the PRC
Why can't my Character level-up?
HOW TO: Make a 1st level PC with a PRC Class or Race
This is one of the most common questions regarding the PRC & the OC (original campaign).
There are two ways to accomplish this & one of them is very complex & requires you to be running a server along with NWNX2, so we will focus on the easy method.
1.) Download & install the PRC according to the instructions in the readme doc.
2.) Download & install the
3.) Run the JavaCC.
4.) Create your new character. Save it in your localvault folder so you can access while inside of NWN.
If you do not do this, you will not be able to use PRC classes or races as a 1st level character. This is due to a limitation of the game engine & currently there is no way around it.
HOW TO: Casting Spells
When using a a PRC class you will notice that any spells, powers or maneuvers that the class may have aren't located in the Spells radial. Due to a hardcoded engine limitation in NWN these items have been placed into the Class radial instead.
HOW TO: Memorize Spells & Powers
Due to hardcoding, you can't use the Bioware spellbook to memorize spells & powers for PRC classes. You have to use the PRC Spellbook found on your class radial.
HOW TO: Setting up the PRC on a Server
NOTE: The ConvoCC is still a work-in-progress. Please report any bugs and issues you might have, after first checking that you have followed this guide, that the issues have not already been fixed, and that it is a reproducable bug. Make sure you include as much information as possible in reports, including at least what OS and database you are running, where you got the ConvoCC from, what haks you are using, how you precached the 2das, what character you are building, and exactly what steps you take to expose the bug. A screenshot of the bug as well as both the serverlog and NWNX-ODBC log files is also very helpful. Without reliable feedback and reports, I cannot improve the ConvoCC. Thank you for your cooperation.
This is a step-by-step guide on how to install the PRC Server Pack.
The PRC Server Pack is needed if you want to do any of the following:
-Use the Conversation Character Creator. This allows the creation of characters with new races, new classes or other custom content at level 1.
-Use the Letoscript enhancements for things such as permanent stat adjustments, etc.
-Use a database other than Bioware's to cache 2da information in.
The system is composed of several components. Firstly, there is
This is an application that hooks into memory locations of the NWServer in order to pass information
into and out of the game. It relies on plugins to provide functionality.
Two plugins are included in the PRC Server Pack:
One is a database plugin,
, which is used to access an
The other is the
Build 24
There is also a precacher tool built into prc.jar and a stand-alone SQLite command line tool. These are used to insert the 2DA files into the database where they can be accessed quicker.
Many servers may already have NWNX2 setup, possibly already using NWNX-ODBC2 to provide database functionality. Some servers use MySQL instead of SQLite as a database. In these cases, the precacher can be set to provide MySQL compatible syntax.
The first step is to download the
PRC Server Pack
If you're using Windows, you should get the .exe installer.
To install the PRC Server Pack, simply run the executable. It should automatically detect your NWN directory. After it has installed itself, it will offer to precache the 2DAs for you straight away.
If you are using another OS there is a .rar version as well, which should be extracted to your NWN directory. Then you will need to manually start the precaching by running the "precache sqlite.bat" file (NOTE: I dont know anything about non-windows OS, so I dont know if a batch file applies or not. If you have more information, please contact the PRC team so this manual can be updated).
If you are looking to add the ConvoCC to an existing server, then you should use the method above (after making a full backup of course). If your existing server uses MySQL, then you will have to use the rar distribution and run "precache mysql.bat" instead. This will produce a file named "out.sql" which you should then run through your database tools. A command like "mysql -u USER -p DATABASENAME < out.sql > out.log" (replace USER and DATABASENAME with the values you use) should work.
Once the precacher has finished, you should have a ready populated database with all the 2DA information in it. This is needed so that SQL queries can be used to retrieve lists of feats etc, rather than lengthy loops over all the rows in the 2DAs.
If you need to precache the 2da files again in the future, for example a new PRC version is released, run the "precache sqlite.bat" file (or "precache mysql.bat" if using MySQL and then process the out.sql file as before) in your NWN directory. This will remove the tables that the precacher previously added, so it should preserve any other existing data. However, it is probably a good idea to make a backup before you update, just to be safe!
Now that you have a populated database, you can go about setting up the ConvoCC
HOW TO: Setting up the ConvoCC on a server
Setting up the ConvoCC is mainly done thru the switch system.
The minimum switches that should be set are:
PRC_CONVOCC_ENABLE - This enables the ConvoCC via the OnClientEnter event.
PRC_CONVOCC_USE_XP_FOR_NEW_CHAR - This uses zero XP on a character to mark them as new.
PRC_USE_DATABASE - Turn on database usage.
PRC_DB_SQLLITE or PRC_DB_MYSQL - Set it to the correct SQL syntax.
PRC_USE_LETOSCRIPT - Turn on Letoscript.
PRC_LETOSCRIPT_NWN_DIR - A string pointing to your NWN installation directory.
If you want further information on switches, see the prc_inc_switch script.
: Letoscript fails to find the NWN directory.
Check the PRC_LETOSCRIPT_NWN_DIR switch. Try different slash options, / // \ \\ as well as having a trailing slash or not.
Check that you are using NWNX-Letoscipt build 24
: Not all options are displayed on occasion
This appears to be lag-related. Try selecting an option and then responding "no" to the confirmation. This should re-generate the list with all the options present, though it may take a few attempts. Hitting ESC may work too.
: No options are present and the conversation cannot be aborted.
This is usually the result of a bug, you can use Alt-F4 to quit NWN without using Ctr-Alt-Delete.
Please report this including what OS and database you are running, where you got the ConvoCC from, what haks you are using, how you precached the 2das, what character you are building, and exactly what steps you take to expose the bug.
HOW TO: Get the PRC
Click on the "PRC Downloads" button at the top of this forum.
Why can't my Character level-up?
This happens when you take a feat that your PC doesn't qualify for. If the feat was taken at 1st level you will have to scrap that PC & start over.
Simple Machines
(Charcoal - MrGrumpy)


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Welcome to our website.
To view product availability in a specific country, select from the country list below. For Investor Relations, please visit our global site.
The Sarix™ IL10 Series mini box and micro dome cameras deliver on customer needs and preferences, these high-definition IP network cameras offer a cost-effective solution for video security needs in small- and medium-sized businesses.
Sarix IL10 cameras are high-definition, cost-effective IP network cameras designed for most any indoor fixed video security application. The cameras produce high-quality, color HD video, and the integrated pre-focused fixed focal length lens makes sharp scene alignment and installation quick and easy. The box camera models offer unique mounting flexibility, and the micro dome models ship with quick snap-in ceiling mounts.
Convenient network connectivity, Power over Ethernet (PoE) models, and a simple Web user interface make for easy plug-and-play finalization of settings and positioning adjustment. And by delivering industry-leading Sarix image quality backed by
Pelco™ by Schneider Electric™, Sarix IL10 Series are value-driven cameras that you can choose with confidence.
The series is compatible with Pelco API v1.0 and the Open Network Video Interface Forum (ONVIF™) Profile S standard for connection with third-party video management systems. And Sarix IL10 also easily connects to Pelco IP and hybrid systems such as Endura™ version 2.0 (or later), Digital Sentry™ version 7.3 (or later), and DX4700™/DX4800™ hybrid video recorders.
Web Interface
Sarix IL10 uses a standard Web browser for easy remote setup and administration. Controls are optimized for easy one-step camera configuration for features including color, exposure, flicker control, and streaming. A one-click shutter allows you to capture sharp JPEG snapshots of the live view for documenting, positioning, or easy event recording.
Video StreamsSarix IL10 cameras can support two simultaneous video streams. The two streams can be compressed in H.264 format that can be individually optimized between highest quality and bandwidth/storage efficiency. The camera supports text overlay with options for time, date, and camera name.
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Sarix IL10 PoE models work with PoE-enabled network switches or power injectors, eliminating the need for separate power supplies and cabling. The 24 Vac models are also offered for installations where 24 Vac power already exists.
Recommended Accessories


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Byat Wednesday, November 30, 2011
Earlier today, we posted that you can send messages via Google Voice using Siri, Control and Launch different apps on your Mac Siri and Even can Control your car using Siri Proxy. Well, we have another amazing video for you.
Using SiriProxy I am able to control any of the devices in my house. These are a couple things I can do in my room so far. More to come!In this video, the hacker shows that how he can control his Entire room using Siri. When he says, Siri, Can you please close my curtains? And siri Closes the curtains for him. The developers has also tried to Tun On the Fan and even to turn off the lights.
From these kind of news, it is clearly shown that Siri is revloutionzing the world by opening many ideas and things. This is all by the help of plamoni who Cracked open Siri's security protocols which lead the developers to put their data so that they can come true their ideas using Siri.
If you found this post useful, dont forget to click the +1 button =>


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John E. Braden 1864-1944, Mary A. (Snider) 1867-1962. Cemetery section O.
Contributed on 4/7/07 by maxjb
Email This Contributor
Record #: 21566
On this site you can upload gravestone photos, locate ancestors and perform genealogy research. If you have a relative buried in Ohio, we encourage you to upload a digital image using our Submit a Photo page. Contributing to this genealogy archive helps family historians and genealogy researchers locate their relatives and complete their family tree.
Submitted: 4/7/07 • Approved: 4/7/07 • Last Updated: 8/13/15 • R21566-G21564-S3


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The Setsumon Information
- Location & Getting There
Overlooking the main street of Hirafu, in the heart of Hirafu Village, the Setsumona is a 2.5-hour drive from New Chitose Airport in Sapporo.
- Accommodation
The Setsumon features a mixture of architecturally appointed studios, one-, two- and three-bedroom apartments, plus 2 spectacular penthouses. The apartments boast full glass floor-to-ceiling windows that open to stunning views of the ski mountains. The Penthouses feature a heated rooftop jacuzzi with sensational views, a fireplace, fully-equipped kitchen, a separate powder room, large sofas in the living room, personal ski dry lockers, outdoor garden and barbeque facilities.
- Facilities
- Library
- Ski rental
- Ski school
- Dining: Kitchen
- Activities
The property offers easy walking access to Hirafu's restaurants, bars and onsens. Winter sport activities are the main pull at Niseko, where even first-timers can try their hand at skiing or snowboarding. After a day on the slopes, relaxing in a onsen is a pleasurable experience. In the summer, Niseko is a great holiday destination for hiking and alphine walks.
- Children
Children are welcome but there are no specific facilities available.


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Pattern Designer Interview - Sidney Brand of Sid's In Stitches
Wednesday, 11 December 2013
This week we have another fabulous Pattern Designer Interview for you! As I have had such a busy week, I am not even going to bore you at all with my chit chat .....(OK....sooo NO need to get out of your chair and jump with joy! LOL) it is straight over to you Sid! :)
When did you start designing patterns?
I've been designing my own patterns most of my life! I began by charting my own needlepoint patterns when I was 12. I've been SELLING my patterns since 1982, but that was when I did counted cross-stitch designs. I live in a historic area and still sell my Historic Savannah Houses cross-stitch charts. I have been designing and selling quilt and purse patterns since 1990. My purse patterns were first available as printed patterns, sold wholesale all over the United States. In 2007 I published my first PDF pattern, which was emailed to the customer. Now they can download them instantly on Etsy, which is very popular!
What led you to this path?
The local quilt store, which sold my cross-stitch designs, wanted the Historic Savannah Houses for quilts, so I came up with Historic Savannah Quilt Squares in paper foundation piecing.
After that, I caught the bug and came up with several quilt designs, in paper foundation piecing and easy construction techniques. At the time, I had young children, and didn't have the concentrated time to sit down and sew complicated designs. One of my first patterns was My Daughter's Dresses, a scrap quilt in paper foundation piecing (made from scraps from all the clothes I had made my oldest daughter). I have always enjoyed making purses (along with clothes), so purse designs were a natural evolution. They are quicker than quilts! There is only so much space for a quilt and you can always find space for another purse!!
What training do you have or are you self taught?
I have been sewing since I was seven, taught by my grandmother. Over the years I have taken many classes in sewing, adjusting patterns for clothing, and quilts. Eventually, I began to teach classes in quilts, accessories, and purses at the local quilt store. I also have a degree in Print Communication, so that helps in writing the patterns. I have a background in arts and crafts, and have taught a Color Wheel class many times to quilt guilds, at a city art program, and at quilt stores.
Describe your process of designing a pattern?
Usually, the idea is the hardest part. I love to get input from my sewing friends on my Facebook page and from previous customers. I draw the purse, sketching with measurements, and then sew from my original idea. Occasionally I make changes or adjustments when making the prototype, but they are very rarely major changes. I try to develop easy construction techniques as I go along, and tend to reuse the easy techniques I have developed through my other patterns.
What do you find the hardest part about designing a pattern and bringing it to the public?
Making a second, and sometimes third, prototype. Also, making the pattern prototype, which I photograph as I sew to make the step-by-step directions. The pressure to remember to take a photo at each step is awful! I want to make the pattern as easy to follow as I can.
How would you describe your design style? Anything unique about your patterns?
My stuff is always easy to sew and FUN! I work very hard to develop construction techniques which may seem unusual, but are always a "simpler" way to sew. Many times, when my patterns are tested (sometimes by students in a class), an experienced sewer will say "That won't work!". I just say "Trust me, you'll be glad you did!" I also like my purses to be crisp, practical, and functional. I have versions of almost all my patterns in my personal purse collection – different types for different purposes!
When you are not working on your own designs, do you like to sew other things? What and for whom?
I have always sewn clothing. I like to make little crafty items for gifts (stuffed animals and gift items). I loved making little outfits (and hats) for my daughters when they were young. Most recently I have sewn for my daughters – a prom dress and an elaborate costume (Lady Macbeth) for a play.
Which do you prefer, the design process or the actual sewing and why?
I love to design, to make it work! But I really love to make purses, because I'm in love with fabrics – bright colors, novelty prints – and the combination of colors.
When do you work on your designs?
Any time of the day or night! That's the benefit of working from home.
Do you have a dedicated work area?
I have a beautiful, roomy studio that is full of my cutting table, sewing table, ironing table, computer desks and (MOSTLY) all of my fabric stash! It's also full of my collections from popular culture (Beatles, Barbies, Jack Skellington, Hot Wheels, etc).
Do you have a favourite fabric type you prefer to work with?
I like 100% quilter's weight, quality cotton.
What advice do you have for a beginner or someone interested in learning to sew bags?
Take a deep breath and follow the directions, step by step. If you're not sure where to start, ask the designer which bag they would suggest for a beginner (my Reversible Bookbag Tote is the easiest pattern I have).
There are a lot of free patterns out there (some are very good), but sometimes it's best to start with a pattern that's been tested and is for sale. If you have a question, email the designer – I love to get questions as it allows me to clarify the pattern if need be!
What is your favourite part of your business?
I like "meeting" so many sewists from all over the world, seeing the fabric combinations they come up with, and hearing their ideas for more bags! I feel like I have so many friends who sew now (actually over 5,000 on my Facebook page)! My Facebook page is a wonderful place to connect with them, but I've also enjoyed many email "pen-pals" who I consider friends.
How do you connect your blog with your business?
My blog works as an addendum to my patterns – giving further hints, techniques, and new ideas (like using strips for a purse or upcycling) that can be used with my patterns or other patterns.
I also like to provide free tutorial (patterns) for items other than purses like placemats or gift items.
Thanks for a fun and interestig interview Sid! You can find out more about Sid via the following links:
Sid's Blog: www.SidQuilts.blogspot.com - Free Tutorials and MORE!
Sid's Store: www.SidQuilts.etsy.com - Unique and Useful Purses and Totes PDF Patterns!
Sid's Website: www.SidsInStitches.com - Great Patterns that are Easy and Fun!
Sid's Facebook Page: http://www.facebook.com/InStitchesPatterns -Join and share your photos!
PLUS Use the code MeetSid at checkout in Sid's Etsy store and get $4.00 off an $8.00 pattern. (Expires January 15, 2014.) How awesome is that!
Next weeks Sewist Interview is with someone whom I came accross when they were making the most AWESOME polymer Clay creatons.....Lately she has moved on to make even awesomer BAGS.....so until next week, happy Christmas sewing!


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Bone Marrow Research
Volume 2011, Article ID 846096, 9 pages
An In Vitro Study of Differentiation of Hematopoietic Cells to Endothelial Cells
1Department of Physiology, Xiangya Medical College, Central South University, Changsha 410078, China
2College of Life Science, Hunan Normal University, Changsha 410081, China
3Everett Medical Center, GHC, Everett, WA 98201, USA
4Benaroya Research Institute and Departments of Biological Structure and Ophthalmology, University of Washington, Seattle, WA 98195, USA
Received 18 July 2011; Revised 26 September 2011; Accepted 26 September 2011
Academic Editor: Joseph H. Antin
Copyright © 2011 Qi Ru Wang et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Bone-marrow-derived endothelial progenitor cells (BM-EPCs) contribute to postnatal neovascularization and therefore are of great interest for cell therapies to treat ischemic diseases. However, their origin and characteristics are still in controversy. In this paper, we identified the origin/lineage of the BM-EPCs that were isolated from bone marrow mononuclear cells and differentiated with the induction of bone-marrow endothelial-cellconditioned medium (ECCM). BM-EPCs were characterized in terms of phenotype, lineage potential, and their functional properties. Endothelial cell colonies derived from BM-EPC were cultured with ECCM for 3 months. Cultured EPC colony cells expressed endothelial cell markers and formed the capillary-like network in vitro. EPC colony cells expressed differential proliferative capacity; some of the colonies exhibited a high proliferative potential (HPP) capacity up to 20 population doublings. More importantly, these HPP-EPCs expressed hematopoietic marker CD45, exhibited endocytic activities, and preserved some of the myeloid cell activity. In addition, the HPP-EPCs secrete various growth factors including VEGF and GM-CSF into the culture medium. The results demonstrate that these EPCs were primarily derived from hematopoietic origin of early precursor cells and maintained high proliferative potential capacity, a feature with a significant potential in the application of cell therapy in ischemic diseases.
1. Introduction
Bone marrow mononuclear cells (BMMNCs) contain endothelial progenitor cells (EPCs) valuable in cell therapy to enhance postischemic neovascularization. It has been shown that BMMNCs, which can be easily prepared from bone marrow extraction, have dramatic effects in the formation of neovascularization in ischemic diseases or tumor model [1–4]. In spite of extensive studies on EPC [3, 5–7], it is still quite challenging to induce all the potential EPCs from BMMNC or bone marrow into functional EPC due to the following reasons: (1) hierarchy of hematopoietic progenitors in bone marrow; (2) EPCs exist as a distinct cell type residing in the bone marrow stroma; (3) imperfect induction conditions in vitro. Extensive literature clearly documented the presence of EPCs in the bone marrow; it is important to elucidate the origin of the BM-EPC and continuously to improve strategies for isolating and characterizing the valuable EPC from BMMNC, thereby ultimately utilizing these EPCs for therapeutic purposes in ischemic and tumor diseases.
We have established and characterized a BMEC line in our lab [8]. BMEC-CM derived from the BMEC line culture enhanced the proliferation and differentiation of hematopoietic progenitors [9–11] and stimulated the proliferation of EPC [12, 13]. In this paper, we present the in vitro model for characterization of bone-marrow-derived EPC with the induction of BMEC-CM. Under this unique condition, a population of bone-marrow-derived EPC has been enriched and characterized. Our data demonstrate that these EPCs were primarily derived from hematopoietic origin of early precursor cells and maintained high proliferative potential (HPP) capacity, a feature with a significant potential in the application of cell therapy in ischemic diseases.
2. Methods
2.1. Culture of Endothelial Cell Colony
Murine bone marrow mononuclear cells (BMMNCs) were prepared. Bone marrow EC-cols were established using the previously described method with modification [12]. Briefly, one million BMMNCs were suspended in DMEM containing 20% FBS and 20% bone-marrow-endothelial-cell-conditioned medium (BMEC-CM, see below) and were seeded onto a fibronectin-coated well of a 24-well tissue plate. After 5 days in culture, cells were trypsinized and replated at low density of cells/well (6-well plate) or 10 cells/well (96-well plate). Each well of 96-well plate or 6-well plate contained 200 μl or 2 mL DMEM with 20% FBS and 20% EC-CM, respectively. Cells were cultured at 37°C, 5% CO2 in a humidified incubator. Media were changed every week. Each well was examined for the growth of endothelial cells every 3 days. In most wells of 96-well plate, one colony was observed in each well. The wells that contained only one colony were selected for the study. In the well of 6-well plate, one big colony (>10,000 cells) was selected and the other endothelial cells and smaller EC-cols were removed with a policeman under microscope after 4 weeks in culture. As a result, only one EC-col was cultured in each well. The cell number of each colony was counted under microscope or counted with a hemacytometer.
2.2. Preparation of Bone-Marrow-Endothelial-Cell-Conditioned Medium
The murine bone-marrow-derived endothelial cell line was established in our laboratory [8]. One hundred thousand immortalized endothelial cells or fresh cultured EPC-derived cells were cultured in DMEM for 48 hours without serum. The conditioned medium from endothelial cell line was named BMEC-CM; the conditioned medium from EPC-derived cells was named EPC-CM. The conditioned media were collected and kept at −20°C before further use.
2.3. Immunofluorescence
Cells from colonies were immunostained with anti-murine CD31 IgG (Sigma), anti-von Willebrand factor (vWF) IgG (Dako), and anti-CD45 IgG (Biolegend), respectively, followed by secondary antibodies conjugated to FITC or Texas-red, using a standard procedure described previously. To assess lectin binding, biotinylated Ulex europaeus agglutinin-I (UEA-I) and streptavidin-Alexa Fluor 488 were applied. In addition, cells were incubated with 10 ug/mL DiI-Ac-LDL for the uptake of acetylated LDL assay as described previously [12].
2.4. Proliferative Potentials
Cell numbers of each colony cultured in the wells of 96-well plate were counted under microscope starting from day 7 of culture and followed up for 30 days. The number of cells per colony cultured in a well of 6-well plate was counted under microscope or with a hemacytometer every two weeks and followed up for 14 weeks. The data were analyzed for the description of the growth curve.
2.5. Vascular Network Formation
Fifty percent BMEC-CM plus 20% F-CM (fibroblast-cell-conditioned medium) was added into a well of 6-well plate in which a large colony has been cultured. Medium was replaced each week. Vascular network formation was monitored every day under an inverted microscopy.
2.6. Secreted Growth Factors
To analyze growth factors secreted into the culture media, cells derived from EC-cols, which have been cultured for more than one and half month in tissue culture incubator, were exposed to serum-free and growth-factor-free DMEM For 48 hours. Conditioned media were collected and analyzed for vascular endothelial growth factor and granulocyte-macrophage colony-stimulating factor (GM-CSF) by ELISA (R and D system). For evaluation of the biological activity of the secreted growth factors in the CM, the serum-free supernatant of EC colony cells (EPC-CM) was tested in the liquid culture system with variable concentrations of 0%, 5%, 10%, 20%, and 40%, respectively; the growth of endothelial cell colony was subsequently evaluated.
2.7. Endocytosis
Endocytosis assays were performed with EC-col-derived cells, macrophages, and HUVECs. The preparation of Candida albicans reagent was by the addition of Candida albicans to DMEM containing 20% FBS. Adherent cells derived from the EC colony (45d) in the 96-well plate were incubated with this solution for 2 hours in tissue culture incubator. Subsequently, cells were stained with Wright-Giemsa's staining. Numbers of Candida albicans internalized by each cell were counted under microscope. Macrophages and HUVECs were included as positive and negative controls, respectively, for endocytosis.
2.8. Statistical Analysis
Results were expressed as means ± SD. Levels of significance were determined using Student's -test. values less than 0.05 were considered statistically significant.
3. Results
3.1. Morphology and Phenotype of EC Colony
BMMNCs were incubated in 20% BMEC-CM for 5 days, this CM-mediated induction significantly promotes the differentiation of the BMMNC towards EPC as shown in Figure 1. After the initial 5-day incubation, BMMNCs were replated in a low-density culture dish in the presence of BMEC-CM. EPC-derived colonies (EC-cols) were formed with variable sizes of colonies containing dozens to thousands of cells per colony.
An EPC colony, negative for CD45 and positive for EC markers, was identified in experiments of the primary EPC colony culture (Figure 2(A)). Interestingly, the CD45-EC+ colony was rarely found in the EPC colony culture with this in vitro condition. CD45-EPC colony can be derived from either angioblasts or mesenchymal stem cells (MSCs) in the bone marrow [14, 15]. We might speculate that this particular CD45-EC+ colony (Figure 2(A)) was derived from angioblast rather than MSC, because MSCs were completely inhibited by cytokines/growth factors presented in the BMEC-CM used for EPC colony culture; this has been demonstrated previously in our lab [12]. In contrast, most of the EPC colonies generated with this in vitro condition, regardless of cultures in the plate of 96 wells or 6 wells, were CD45+ EC+ (Figure 2(B)). Given the fact that EPCs derived from hematopoietic lineage express CD45+, it is thus logical to propose that the CD45+ bone marrow-derived EPCs are originated from hematopoietic lineage.
EPCs possess differential proliferative capacity depending on the hierarchy of hematopoietic progenitor that they are derived from. Quantitatively, we have observed thatEPCs were derived from bone marrow mononuclear cells. For example, if the EPC is derived from a myeloid progenitor or monocyte, this EPC has limited proliferative capacity, resulting in a small colony [16]. On the contrary, if the EPC is derived from hematopoietic stem cell or an undifferentiated early precursor in this lineage, this EPC has potent proliferative capacity, resulting in a large colony. The percentage of high proliferative potential EPC colonies is 1-2% among all the EPC colonies. This discrepancy of EPC proliferative capacity has also been attributed to the hierarchy of hematopoietic progenitors in bone marrow [17]. Next, we designed experiments to evaluate the EPC proliferation capacity.
3.2. EPC Proliferation
Proliferative capacity of a single endothelial progenitor cell was evaluated by the colony size. After 5-day culture of BMMNC with BMEC-CM, cells were tripsinized and replated for evaluation of their proliferative capacity. To examine colony size of 30-day culture, cells were plated at 10 cells/well of 96-well plates. At this low cell-plating density, one colony per well was achieved in most of the wells of 96-well plates. To examine the high proliferative potential colony, cells/well of 6-well plate were plated. After 4 weeks in culture, one large endothelial cell colony was selected and allowed to grow in one well (see Section 2). Eighty-two single cell colonies were formed from wells of 96-well plate, and 8 high proliferative potential colonies were observed from 6-well plates. Among the 82 colonies, 72% of single EPC gave rise to colonies containing cells ranging from 101 to 1000 cells, 9% ranging from 50–100 cells, and 19% ranging from 1001 to 5000 cells or more in a period of 3 weeks of culture (Figure 3(a)). The cell number/per colony was cells in the eight high proliferative potential colonies in a period of 14 weeks of culture (Figure 3(b)). Samples of these colony-derived cells were reexamined for cell markers by immunofluorescence, they are positive for EC markers and positive for CD45. These EPCs were expanded for 20 population doublings.
3.3. Angiogenic Capacity of the Colony Cells
EPC colony cells derived from BMMNC showed capacity of forming capillary-like network structure in vitro. We have found that 25–37% of EPC colonies have the capacity to form capillary-like structure with appropriate culture condition. EPC colony cells (45d) formed capillary-like structure when exposed to 50% BMEC-CM plus 20% F-CM for 2 days (Figure 4(a)).capillary-like structures per 20 × microscopic field were formed. In contrast, the capillary-like structure did not form (0 to 1 capillary-like structure per field) when exposed to VEGF matrigel condition for the same time points.
3.4. Growth Factors Produced by EPC In Vitro
BMMNC-derived EPCs were cultured in serum-free and BMEC-CM-free medium. The cultured medium was harvested after 48-hour incubation. We evaluated the level of cytokines secreted by EPC using ELISA assay. Over a 48-hour culture, EPCs secreted VEGF of pg/106 cells/mL and GM-CSF of pg/106 cells/mL (Figure 5(a)). The effect of various concentrations of the supernatant (EPC-CM) on EC-col formation was further analyzed. The EC-cols were formed in the presence of EPC-CM. There was a dose-dependent effect of EPC-CM on the growth of EC-cols (Figure 5(b)). In comparison to HUVEC-CM, EPC-CM showed a stronger stimulation for the formation of EC-cols (Figure 5(b)).
3.5. Endocytic Capability
A critical feature of monocytes is the endocytic activity. EPCs derived from CFU-GM or myeloid lineage maintain strong endocytic activity. We examined the endocytic capability of EPC-col-derived cells. EPC-col-derived cells were incubated with Candida albicans, and the number of the Candida albicans internalized by each cell was counted. Macrophages and HUVEC were used as controls. The result showed that cells derived from EPC-cols internalized significantly more Candida albicans than HUVEC (), but less than macrophages (). Monocytes/macrophages are derived from myeloid lineage and CD45+, exhibiting a strong phagocytic activity (Figure 6(a)). Conversely, HUVECs are derived from angioblasts [14] and CD45− [18], exhibiting a weak phagocytic activity (Figure 6(c)). In fact, these EPCs maintained some of the phagocytic feature, one of the critical characteristics of hematopoietic lineage cells. More importantly, this phagocytic activity demonstrated by these EPCs argues against the possibility of their angioblast origin.
4. Discussion
In this study, with the induction of BMEC-CM, BMMNC gave rise to cell colonies that expressed EC markers, incorporated Ac-LDL, reacted with endothelial specific Ulex europaeus lectin; showed endothelial morphology, exhibited a high proliferative capacity, and formed capillary-like structures, all of these indicating they are EPC.
A variety of stem cells/progenitor cells in bone marrow can be induced and differentiated into EPC in vivo and in vitro. The rare hemangioblasts and their progeny angioblasts [14, 19–22], the hematopoietic stem cells [23] and their progeny of myeloid lineage [24–26], and the multipotent adult progenitor cells and/or MSC [15] are the primary sources to give rise to EPC. In this study, the growth of MSC from BMMNC was completely inhibited as described in our previous report [12]. Therefore, the EPC generated in this report (hereafter termed HS-EPC) could be originated either from hemangioblasts, angioblasts, and their progeny, or from hematopoietic stem cells and their progeny (Figure 7). It is highly unlikely that HS-EPCs are originated from angioblasts for the following reasons: (1) the EPCs derived from angioblasts have higher proliferative capacity relative to HS-EPC. For example, the cord-blood-derived HPP-EPC could be expanded for at least 100 population doublings and yield 1010 to 1012 cells per EPC after 90-day incubation [27]. HUVECs and HAECs derived from angioblasts can be passaged for at least 40 population doublings in vitro [18]. In contrast, HS-EPC can be expanded for 20 population doublings and yield cells per EPC after 14-week incubation (Figure 3(b)). (2) EPC derived from angioblasts responded well to VEGF; VEGF is a potent stimulator for the formation of capillary-like structure for EPC derived from angioblasts [27]. On the contrary, HS-EPC responded poorly to VEGF in the formation of capillary-like structure (Figure 4). Moreover, EC-CMs or F-CMs rather than VEGF were more potent stimulators for the formation of capillary-like structures on HS-EPC cells (Figure 4). (3) Cells derived from angioblasts showed a weak phagocytic capability (Figure 6, HUVEC), but HS-EPC exhibited a significantly higher phagocytic ability than HUVEC (angioblast progeny. (4) EPCs derived from angioblasts or MSC were negative for CD45, whereas HS-EPCs were positive for CD45 (Figure 2(b)). It is most likely that HS-EPCs are originated from hematopoietic stem cells and their early progeny (Figure 7). It has been reported that the hematopoietic stem cells and their progeny of myeloid lineage have been induced to differentiate into endothelial cells [2, 16, 23, 24, 28]. Pleiotrophin might induce transdifferentiation of monocytes into functional endothelial cells [29]; likewise, TNFα also significantly facilitates the endothelial differentiation of myeloid cells in vitro and in vivo [30]. Madlambayan et al. [31] demonstrate that myeloid progenitor cells directly participate in new blood vessel formation in response to SDF-1α. They report that secondary transplantation of single hematopoietic stem cells showed that HSCs are a long-term source for neovasculogenesis. Our experiments provide evidence that hematopoietic cells can differentiate into endothelium in a liquid culture with EC-CM. We believe that EC-CM contains various factors including VEGF, SDF-1, and TNF-α and unknown factors that play a synergism effect in the induction of hematopoietic cells to endothelial cells.
A common feature of EPC derived from myeloid linage and monocytes is their limited proliferative capacity [16, 32]. Interestingly, HS-EPC, positive for CD45, exhibited much higher capacity for proliferation in comparison to EPC derived from myeloid linage cells; for example, one HS-EPC yields about EC (Figure 3(b)), only hematopoietic-stem-cell-/early-progenitor-originated and differentiated endothelia lineage cells can possess such high proliferative capacity. This high proliferative capacity is indeed the characteristic of stem/precursor cell of hematopoietic lineage. We believe that the various cytokines and unidentified molecules secreted by the BMEC line (used for the preparation of BMEC-CM) [9] and their synergistic effects played a significant role in promoting the adherence of hematopoietic stem cells in the initial BMMNC culture; moreover, these factors not only facilitate the survivor, proliferation, and differentiation of stem cell/progenitor, but also induce stem cells to differentiate towards EPC lineage and stimulate their proliferation [12, 13]. The secreted factors/molecules preserved the characteristics of hematopoietic stem cells during the differentiation towards EPC, such as high capacity of proliferation. Thus, one hematopoietic stem cell or progenitor cell can result in million of endothelial cells under the induction of BMEC-EM. This phenotype is extremely important given their potential in repair in ischemic diseases. For example, a recent study showed that after intracoronary transplantation of bone marrow cells enriched in CD34/CD45+ and CD133/CD45+, patients with ischemic heart disease showed a significantly reduced size of infract area and an increased global ejection fraction as well as infract wall movement velocity [33]. Our study provides increasingly important insight for the treatment of ischemic disease by using HS-EPC. This method for isolating EPC is quite unique because it induced the early hematopoietic stem cells rather than late differentiated progenitors; thus, the high proliferative potential capacity is a trademark of this in vitro isolation technique, a critical feature in translational research in ischemic diseases. To further categorize the specific cell markers expressed on the HS-EPC is important for the sorting of this unique population of EPC.
In this paper, we present an in vitro model of cell differentiation from hematopoietic stem/progenitor cells in BMMNC to endothelial linage. Given the advantage of easy access of bone marrow tissue and negative immune rejection by using self-bone-marrow cells, HS-EPC would be an important source for cell therapy in ischemic diseases. It is thus important to further elucidate the mechanisms of hematopoietic stem cell differentiation to endothelial linage.
This work was supported by National Natural Science Foundation of China Grant 39970092 (to Q. R. Wang) and by National Institute of Health Grant EY014150 (to Q. Yan).
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Each of CHN's regional offices is equipped to assist clients with nutritional needs. The Food Banks in Denver, Fort Collins, Greeley and Colorado Springs offer food items to help supplement clients' weekly nutritional needs. CHN's Grand Junction office is able to provide nutritional assistance in grocery vouchers for eligible clients.
See a Case Manager to find out if you are eligible for nutritional assistance.
The USDA Website and Consumer Guide to Food Safety provide very thorough information on what to do in emergency situations. Follow the links below
to learn more.


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PROGRAMS & EVENTS / Parties and Picnics
AW Halloween Parties and Parade
All classrooms have Halloween parties. The students parade around Avoca West on Halloween.
Winter Party
Held on the Friday before Winter Break begins, this fun party is run by the room parents at the end of the day to celebrate all of the students' hard work to that point of the school year as well as the upcoming holidays.
Year-End Picnic
The year-end picnic is held on the last day of school for all grades to celebrate the year. Pizza is provided by the PTC and room parents coordinate additional food, beverages and treats.


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Office 365 turns one, but success is tough to tally
A year after the launch of Microsoft's ambitious Office 365, it's almost impossible for outsiders to get a grip on how the software-by-subscription program has done, analysts admitted today.
Microsoft kicked off Office 365 — a revamped program for businesses and a new attempt to convince consumers to subscribe indefinitely rather than buy the software every few years — on Jan. 29, 2013.
Since then, Microsoft has disclosed very few details about Office 365's revenue or subscriber performance, other than to occasionally tout the number of consumers who have signed up for the $100-per-year Home Premium.
"In its [SEC and earnings] disclosures, Microsoft talks about revenue at times, but the fact is a huge chunk [of Office 365] is really about revenue from desktop licenses that are just licensed by subscription," said Melissa Webster, an analyst with IDC. "In other words, they're moving revenue off one line and on another. That's not growth."
The last time Microsoft mentioned Office 365 revenue was in mid-2013, when it said the rent-not-buy program was at an annual "run rate" of $1.5 billion, meaning that at its then-current pace, it would generate that amount over the next 12 months.
The company has also pegged Home Premium subscriptions at various times in the last year, most recently last week when it said it had 3.5 million on that edition's rolls, an increase of 1.5 million from the last update in October that's worth $350 million in annual revenue.
Webster's point was that any numbers from Microsoft for enterprise Office 365 subscription revenue was misleading, since much of it was not new, but simply a change of licensing from the traditional "perpetual," where companies bought licenses with rights to use the software as long as they wanted, to subscription.
"At least half is not new revenue, and not a new revenue stream," Webster said, no matter how the media interprets Microsoft's rare disclosures with its headlines. "At least half is just desktop software licensed a different way." She estimated that 60% of the Office 365 revenue was derived directly from the desktop licenses included with most plans.
In a research note last year, Webster called the run rate increases that Microsoft boasted of as an "indifferent" boost to actual revenue, arguing that the real net-new income was approximately one-fourth of Redmond's number once migrations from earlier programs and the switch in licensing were taken into account.
However, she did acknowledge that Microsoft has been drawing some new customers to Office 365, many of them small- or medium-sized businesses, for the hosted services like Exchange and SharePoint that are offered alongside the desktop software they used already.
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Large Education
Large Crystal Icons v.2012.1
Large Crystal Icons include images of crystals and gems that can be used for advertisement design, for decorating websites and blogs and will be especially suitable for adding some spice to presentations and printed materials.
Large Vector Icons v.2010.1
Large Vector Icons represent a variety of objects and concepts. They can be used in software interfaces or web design. High-resolution icons (512x512 pixels) are perfect for splash-screens and can be used in presentations and printed publications.
Large SEO Icons v.2013.1
The set of Large SEO Icons includes images for designing applications and websites related to search engine optimization, social media marketing and site promotion. They represent a variety of search and analysis operations, objects and concepts.
Desktop Education Icons v.2012.1
To make the interface of your educational site as engaging and intuitive as possible, all you need is a collection of Desktop Education Icons. They are readily available online and depict all the commonly used subjects, actions and tasks.
Large Buffet Icons v.2011.1
Large Buffet Icons is a collection of stock icons that includes a variety of images related to cooking and restaurant business. Each image is provided in 5 resolutions and 3 file formats (PNG, ICO and BMP). You can use these icons for web design.
Large Shop Icons v.2011.1
The collection of Large Shop Icons includes images in sizes from 16x16 pixels to 512x512 pixels, in file formats of ICO, BMP and PNG. All the icons are created by professional designers and present the highest possible quality.
Large Boss Icons installer v.188.8.131.52
Collection of Large Boss Icons includes images of all kinds of bosses, commanders and managers: from army and police officers to corporate executives and royal family with Various resolutions (from 16x16 to 512x512 px) and image formats are included.
Free Large Boss Icons v.2013.1
The set of Free Large Boss Icons includes images of all kinds of bosses, commanders and managers: from army and police officers to corporate executives and royal family. Various resolutions (from 16x16 to 512x512) and image formats are included.
Education Web Elements
Education themed graphic images and web elements, including HTML web templates with a education theme, stock photos of all types of education, schools and related educational items. Great collection for education related businesses, schools, tutors and
Large Logistics Icons v.2011.1
Large Logistics Icons allow Web designers and application developers produce professional-looking products for logistics and storage specialists, commercial and business applications.
Large Money Icons v.2011.1
Large Money Icons is a set of money-related icons for developers of business and finance applications, websites and blogs. Icons have a bright color palette, smooth and well-rounded edges. They are delivered in a variety of formats and sizes.


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Men's Friday: This Men's bible Sudy will by studying the Old and New Testament. All men are invited to attend. No preparation work needed! We meet in the Hearts Room every Friday at 6:45 – 7:30 AM. Contact: Gary Smith, 942-1718 or Bill McDonagh, 942-1534.
TMIY – That Man is You! is a dynamic 26-week interactive men's program focused on developing men by deepening their relationship with Jesus and providing tools to explore their faith. TMIY combines the best, current social science research with teachings from Scripture and the Catholic Faith developing a vision of authentic men capable of transforming themselves, their families and their communities. Friday mornings 6:00 – 7:30 am. Contact TJ Ackert, 247-0736. Regular attendance is worthwhile but not required.
Check out this YouTube clip: http://youtu.be/BQcxuk6AcvY
More information can be found at the thatmanisyou.org.
Please view this short video clip on the TMIY program and its impact on men around the country:


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emersion DESIGN, in partnership with Community Design Alliance, was commissioned to create a design and renderings for fundraising for the conversion of a utility plant into a row house. The large volume lends itself to open storage on the first floor and a raised workout, crew social area on the second. The elevated gathering space opens up to the exterior with a view of the river and city skyline. This renovation will be the first phase of a regional sports complex on the site of the old Champion Mill site in Hamilton, Ohio and will serve as a backdrop to the baseball stadium's outfield. The project is currently in fundraising mode.
Renovation of Utility Plant for Sports Use
Phase One of a Master Plan
Great Miami Rowing Center
Project contact
Chad Edwards
project manager
513 841 3907
project manager
513 841 3907
awerawer awerwer


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"Hi Stacy, I met this one horse a week ago that a friend of mine has had ever since birth. Six years ago when Vick was two and a half she had a guy training/acquainting Vick with the saddle he (the trainer) got sidetracked!!! He left Vick in the roundpen alone (with all the gear) REALLY. Anyway Vick took it upon himself to dispose of his foreign attachments. Thus getting all tangled up. Ever since his hind left leg in swollen. Horses are my life in a sense. I would like to have your opinion. If there is still a chance for it to heal? And if so what to do????"-Katie S.
I would recommend finding a vet that specializes in lameness. Often vets that deal with performance horses or racehorses (TB or Standardbred) are excellent leg vets. Get a professional opinion. Much like visiting your doctor vs another doctor, opinions can vary so multiple opinions are also valuable.
Sometimes even long standing injuries can be treated because the horses don't naturally fully rest like they need. For example, sometimes stall rest can allow something to heal that has not healed in the pasture simply because the horse keeps re-injuring every time he feels better. I am not diagnosing here. I am recommending finding a vet who can take a look and I am saying, yes, there is hope.


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All the schools are now linked to their LST reports as well.
For all non-acceptances, assume they will be sent by email unless otherwise noted. For international applicants, assume email for all news.
No status checker. It's Yale.
Acceptances: Call
Area Code: 203
Not-acceptances: Asha says it will be by mail (thanks, Koala!) at the beginning of the cycle, but by email towards the end. (it appears now to be only by email)
Complete (up to a month)
JS1 (can take anywhere from a week to several months, especially if you are held) (in mailings, also by email)
Decision Rendered
May have date changes.
Acceptances: Call (email if international)
Area Code: 617
Submitted for Review
Shouldn't take more than a few days
No date changes
Acceptances: Phone
Area Code: 650
Last year, if your status changed to "decision letter sent" and you hadn't received a phone call or email, you had been waitlisted/dinged.
Complete (two weeks)
Interview Request (WAIT, WHAT??? start reading from here)
No date changes.
Acceptances: Mail. Columbia appears to be emailing some acceptances now. (thanks, residentemma!)
Holds: Email
Letter contains Butler or Hammy info; other merit aid comes later
Complete (up to two weeks)
Under Review (up to six weeks)
Under Review II (most people)
(Invited to Interview)
(Interview Scheduled)
Under Review (basically, switches back after you have your interview)
Date Changes
Acceptances: email, status checker changes simultaneously (thanks and congrats, kershka!)
Waitlists: email, status checker changes simultaneously (thanks, alinor!)
midwest17 wrote:Since I've seen a lot of questions about this lately, here is my best understanding of the status checker journey for people who are admitted:
Application Received
Application Complete (you get an email for this)
Application Under Review (UR 1) <- indicates first committee review of your file
(OPTIONAL) Application Under Review (UR 1.5) <- I did not receive this step, but I believe some people did
Invited for Interview
Application Under Review (UR 2) <- generally immediately after your interview, indicates that the interview is done
Application Under Review (UR 3) <- indicates second committee review of your file
Application Under Review (UR 4) <- most (all?) people get this in the days leading up to decisions being released. Both waves of decisions this year have been on Tuesday; UR4s have started on Friday and continued on Sunday/Monday/Tuesday. As far as I know, getting UR 4 happens whether you're getting admitted, WL'd, or dinged in the wave.
Under Review (a few days)
UR 1 (date change)
UR 2 (date change)
Decision Letter Sent (DLS)
NYU goes from complete to UR quickly. You may not have the same number of UR dates. It appears there is a slight pattern to the UR changes (those who submitted on the 20th then have the 23rd, 29th, and 1st, before DLS on the 10th, etc) but not significant.
Acceptances: Call, but you can try to check the Admitted Students Website to see once you go DLS. This may take till around four or five EST to be up and running. The phone call can take a few days.
Area Code: 212 or 201 (thanks, Bom!) or 646 (thanks, Theopliske8711!)
Admitted Students Website
Under Review (UR 1)
Under Review Date Change (UR 2)
Acceptances: Call
Area Code: 215 (thanks, kershka!)
Non-acceptances: email
There appears to be a fast turnover from UR 2 to RD acceptance.
UVA has a status checker but no status updates. It notes when you are complete (I think you get an email as well). It changes after you are accepted as well.
Acceptances: Phone call OR email
Non-Acceptances: email (thanks, Philly ). After you get this, your status checker changes to "Please check your email inbox for an update on your application status. If you did not receive the update, please contact the Admissions Office at..." (thanks, livefromannarbor :'( )
Area Code: 434
Complete (a few days)
Under Review (a few weeks)
Berkeley has UR date changes but they do not appear to mean anything.
If you are pushed to faculty review...
Faculty Review 1
Faculty Review 2
Acceptances: Status Checker and simultaneous email OR phone call. People who get calls will also get an email later.
Area Code: 510
Not-acceptances: email
The Magical Michigan Status Checker
Complete (about a week)
It will take several weeks to receive Michigan's status checker. Once you do, it will be updated every day because Michigan is awesome.
Acceptances: Status checker, mail
Scholarships: Admitted Students' Website
Complete (like, a day)
Under Review (if PT, quickly, if RD, not so quickly ) (RD seems to take about a week)
Decision Letter Sent; Watch for Email
Acceptances: Email, letter arrives later
Not acceptances: Email (some have received it at really weird hours)
Scholarships: Email about a week or two later to fill out the application. Scholarships should be arriving before April 1st.
A lot of RD people who submitted from September to November seem to be hearing now (thanks, NoDayButToday!)
Decision Letter Available within 24 Hours
You stay incomplete at Northwestern until you complete any requested interviews and the interviewer has submitted the assessment. If a lot of time has gone between the two, you might want to call because the status checker isn't always updated (thanks, alex.cm!).
Once you get "decision letter available," (through status checker or email) you can refresh the status checker page as much to your heart's content until the letter shows up. (thanks, objection_your_honor!)
Remember to update NU with your interview date!
Acceptances: Status checker, email
Complete (a long time)
[Interview request]
[Interview has been scheduled]
Congrats! update
You stay incomplete at Cornell for a very long time. Don't get worried!
Acceptances: Email
Complete (a week or so)
Complete 2
Interview Request
Complete 3
(Additional Completes)
Three completes, with the interview request coming after the second, appears to be the general trend, but not always.
You can also check the ASW website, like with NYU here. Click on "no password?" and then request one by putting in your email. If they don't have a password for you, then they don't. If they do have one--congrats!
Acceptances: Mail (envelope is small!)
Admitted Students Website
Status checker
Admission granted
Acceptances: Status checker and call from Dean
Area Code: 512 (thanks, cannibal ox!)
(Interview Request)
Decision Mailed
It shouldn't take too long to go complete
Acceptances: Mail (it's a large package—you can contact FedEx and see if one weighing more than 5 lbs from Vandy is on your way once your status changes. It should arrive two days later.)
Not Acceptances: In previous years, the acceptances have been sent by FedEx and the non-acceptances by USPS (I think), which makes sense when you think it isn't a package.
UCLA doesn't have a status checker. They email you when they receive your application and when you go complete, and call if you are accepted.
Acceptances: Call
Area Code: 310
Committee 1st Read
Committee 2nd Read
Final Review
Decision Made
Explanation for the status checker
Acceptance: email (thank you, 2014entering2014!)
Minnesota (thanks, cannibal ox!)
Received (?)
In Review
Admitted - Congratulations!
Acceptance: Phone Call
Area Code: 612
Scholarship: Snail Mail (~1 week later)
WUSTL (thanks, Fiero85!)
Application Documents Received (within a few days) very quickly, remained on this status longest.
Complete (after a few weeks)
Email appears to be the more accurate form of communication, and is used for acceptances, interview requests, and scholarships. Casual phone interviews have been prevalent this cycle and are the usual step between complete and acceptance shortly after (1-2 weeks tops).
Acceptance: Email
Boston College
Under Review (can take awhile)
Acceptance: email (thank you, kimkardashian!)
University of Washington:
Under Review
Acceptance: Email
Submit--Confirmation Email (takes about a week)
UR 2 (date change)
Acceptance: Call (205)
Scholarship: Call (205)
thanks, zippernicus!
Date Changes (status stays complete)
Decision: email (thank you, kimkardashian!)
Wisconsin (thanks, Serett!)
Under Review
Decision Made
Decision: email
Georgia (thanks, musharraf!)
Decisions: email (letter arrives later for acceptances)
No date changes.
University of Connecticut
Message at top will say "under review" when app goes under
Penn State (thanks, Neteshy!)
Decision: email (may call a bit later)
Syracuse (thanks, Neteshy!)
Decisions: by mail, in a padded envelope because it comes with a t-shirt ( ). Letter contains scholarship offer.
CUNY (thanks, Neteshy!)
Decisions: email to check status checker, physical letter sent later
Creighton (thanks, Neteshy!)
Decisions: by mail
Under Review
Please add the other schools you have applied to in the comments and I'll add it to the OP!


text:
Mason Katz is being more patient, and the hits, home runs and RBIs are coming a lot faster.
Katz led the LSU baseball team with 13 home runs last season, and he has matched that total halfway through this year. He leads the nation with 49 RBIs — one fewer than he had last season — and he's hitting .419 — 99 points higher than last season — as the No. 2 Tigers prepare to host No. 9 Kentucky in a Southeastern Conference series beginning Friday night in Alex Box Stadium.
Coach Paul Mainieri said Katz is having the kind of season that could be worthy of player of the year awards like the Dick Howser Trophy and the Golden Spikes Award.
"Those are video game stats," Mainieri said. "He's just having an unbelievable year. I think it's in another stratosphere."
Katz said a key to his success has been patience — not just taking more pitches but waiting longer before deciding whether a pitch is worth swinging at and understanding he can swing later and drive the ball to right or right-center field instead of swinging early and trying to pull the ball.
He has 15 strikeouts in 128 plate appearances, putting him on pace to fall well short of the 52 strikeouts he had last season.
"I think I've matured a lot," he said. "I'm not chasing bad pitches, and I think that's a huge thing for me. I'm sticking to my approach really well."
Katz, who primarily batted third last season, has moved to fifth. Freshman Alex Bregman stepped in at No. 3 and is batting an SEC-best .440. Raph Rhymes, who hit a school-record .431 last season, is batting .327 and has reached base in every game but one in the No. 4 spot, giving Katz plenty of opportunities to drive in runs.
"He's laid off some pitches this year that in past years he might have swung at — high fastballs and breaking balls in the dirt — because he would go up there trying to jack a ball out of the park," Mainieri said. "Now he's willing to take a base hit to the opposite field.
"When you're hitting with runners on base all the time and you know that a single can put runs on the board for your team, you're more willing to do that. When you're hitting with no one on base and you're thinking the only way you can score is to hit one out of the ballpark, it makes it a little more difficult."
Junior third baseman Christian Ibarra has provided protection for Katz by hitting .330 with 20 RBI in the No. 6 hole, making opposing pitchers reluctant to pitch around Katz.
"You can't really pick and choose who to pitch to because anybody in the lineup can hurt you," Katz said. "And they don't really have any place to put me because other guys are always on base."
Katz leads the SEC in slugging percentage (.888) and on-base percentage (.519), and he's one of four Tigers — joining Bregman, Rhymes and Ibarra — in the top 10 in runs.
"When I get on base," Rhymes said, "I get ready to run because I know most of the time I'm scoring."
Katz's home runs have taken a lot of RBI opportunities away from Ibarra, who's content to bat with the bases empty under those circumstances.
"When Mason hits a home run in front of me," Ibarra said, "I go up there thinking I'm just going to try and get a hit and keep this inning going."
Mainieri said he has marveled at how many of Katz's run-producing hits have come in clutch situations. Katz generally hasn't padded his statistics against deep-in-the-bullpen relievers but instead has gotten big hits that have helped push the Tigers to a 27-2 record. They're within a victory Friday of matching the 1986 team's school-record start.
"It seems every home run he has hit and every RBI he has had has come at a time when it has mattered most," Mainieri said. "If a homer didn't tie the game or give us the lead, it got us back in the game or extended a precariously small lead. He's just had a phenomenal year. I don't know if he can keep it up. I think he's a great player and a great hitter. If he does less than he did in the first half, he's still going to have a great year."
Katz is on pace to hit 25-plus homers. Former Tiger Matt Clark hit an NCAA-best 28 in 2008, the only time in the past 12 years an LSU player has hit more than 23.
Rhymes said Katz's home run pace, which has come mostly in cold weather, "really is scary."
"I wouldn't be surprised if he hit 30," he said. "Once the weather warms up and that ball starts flying out, he's going to really be dangerous."
Katz, a senior from Harahan and Jesuit High School, figures to draw more attention from professional scouts than he did last year, when he wasn't drafted. But he said he's not concerned with the impression he's making on scouts.
"Honestly I don't care at all about that. I care about LSU," he said. "That's why I came back. It was a no-doubter. When people asked me about the draft last year, I said I don't even really want to go. I want to stay here. That's exactly how I feel. If I could stay here next year, I would — no doubt.
"I don't know if I've opened (scouts') eyes and, if I have, I don't really care. I hope I've opened eyes for this trip we're on — on the road to Omaha."


text:
Magnx is online physics puzzler all about magnetic power.
Object of Magnx is to connect magnetic objects to get smiley to the target zone. You can do this by clicking on an object, to switch the magnet on or off.
Do this in the correct order to solve all twenty levels. Happy Puzzling!
Tags: Puzzle Game


text:
Buy 10 stickers, get 50% off. The more you stick, the more you save.
In honor of Buttercup, a true hero.
forever young adult che guevera cat young adult dystopia books movies literature
Loading more work by 4everYA...
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text:
Those with an interest in helping others and a love of children may consider a pediatrics residency program. Pediatricians are doctors who specialize in working with children and are responsible for their physical, mental, and emotional development and care.
Before embarking on a pediatrics residency program, students need to have completed an undergraduate degree and medical degree. Once they start their residency program, they'll get to put their knowledge into practice, helping young patients and working with more experienced physicians.
After completing a residency program, you'll have the option to complete a fellowship for several more years. This is a requirement for those who wish to practice a very specialized field of medicine, like pediatric cardiology or pediatric oncology. If you don't wish to specialize further, you can obtain your license to practice medicine and work for an established health care provider or open your own practice.


text:
Nicaraguan American Ramon Uriel Gutierrez Mejia always looks forward to the holiday season, but not for gifts and celebration.
Instead, his anticipation is for a traditional Nicaraguan dish: stuffed hen.
" Gallina rellena means tradition," said Mejia, whose parents arrived in the United States in 1986. "It means keeping my grandmother's memory alive. It brings the family together. We get to enjoy good food together as a family."
Several Hispanic cultures have signature traditional dishes for Noche Buena, or Christmas Eve. For example, many Cuban Americans enjoy roasted pig, cooked using a caja china, a type of roasting box.
Many Nicaraguans, however, feast on gallina rellena.
In Sweetwater, where Mejia and his mother, Martha Mejia, operate Madroño Restaurant, the staff has over 100 orders from Nicaraguan Americans who will pick up the dish on Dec. 24. Martha learned of the recipe from her late mother, Maria Mejia Zeledon.
"I am teaching it to my kids and hoping my grandchildren will learn to carry it on in the next generation," she said.
In areas with concentrations of Nicaraguans, such as Hialeah, Sweetwater and Little Havana, some stores advertise the holiday favorite. The dish, which typically sells for about $65, usually includes a stuffed hen served with rice, garlic toast and salad.
What sets the dish apart is the relleno, which translates to stuffing. There are two kinds of stuffing in Nicaragua: one originating from the northern part of the country and the other from the southern area, Ramon said.
Recipes can vary, depending on the household. Stuffing from the north is like a sandwich paste. Southern stuffing, which is more common in South Florida, is made with pork, carrots, capers, raisins, ketchup, mustard, onions, olives and potatos, Ramon said. Once mixed, it is stuffed inside the hen and placed in the oven. The relleno gives the hen its flavor.
"The hen is similar to a chicken in size, but the meat is similar to turkey," said Ramon. "The meat is darker, dryer and rough."
It takes about eight hours to bake the hen.
Xiomara Faenz arrived to the United States in 1979, and gallina rellena is present every Christmas Eve at her household.
"It makes me think of our roots," she said of the meal. "We are always thinking of our land and remembering it."
Also, nacatamal, which is typically pork, rice, capers, potatoes, onions and tomatoes wrapped in a plantain-leaf pillow, is served on Christmas and New Year's Eve.
For dessert, there is pio quinto, which is cake drenched in rum, topped with custard and dusted with cinnamon.
"This is a way to maintain the tradition," Ramon said. "Everyone knows Christmas Eve is gallina day."


text:
Twin brothers, Ahkeem Boyd and Ahkeel Boyd combined for 60 points to lead Stories of Success (SOS) Basketball Academy to an emphatic 130-92 demolition of Trailblazers in the Men's Premier Division...
You are here
TSTT unveils model smart home
At an upscale gated community in Chaguanas yesterday morning, TSTT unveiled its pilot project for gigabit connections to the home. Each of the houses in the Legacy Housing Development will be wired using fiber optic cable that will carry an Internet connection clocking in at 1,000 megabits of data. It's a speed that acting CEO George Hill struggled to make real for the audience in attendance. First, he explained that the speed was "equivalent to downloading 100 million characters of text in one second".
Then, he noted that it would be possible to effortlessly stream "five high-definition videos at the same time on a 1Gb connection while still having room to email and surf the web". Finally, he suggested that the connection was "equivalent to using 100 DVD players at the same time". It's a big pipeline to the Internet and changes the discussion about connectivity from how fast to what do I do next? It's a question that the residents of Legacy Housing will be exploring during a trial of the service that's expected to run for at least six months.
During that time the residents will report on their use of the service and experiences with it, a process that will guide TSTT on creating packages that will be offered to the public. The telecommunications company demonstrated the service, which incorporates much of its QuadPlay initiative, to Minister of Public Utilities Nizam Baksh during a tour of a model home at the housing community which has been wired to demonstrate an ideal deployment of hardware connections to the massive pipeline.
TSTT has now prepared its infrastructure to deliver gigabit Internet connectivity to 10,000 homes in Trinidad, 70 per cent of which are located in the north of the country. The company plans to increase the number of homes eligible for the service to 40,000 by the end of 2014. TSTT had no pricing for the service, noting that it would create its packages for the public after studying the results of the Legacy Housing project.
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text:
Ray Ban Caravan Solid RB3136 White Sunglasses
$135.00 $24.99
Ray Ban Caravan Solid RB3136 White Sunglasses
· FOR: Women & Men
Originally launched in 1957, Ray-Ban Caravan sunglasses are a streamlined, geometric model and an alternative to the classic Aviator Sunglasses . The Ray-Ban signature logo is displayed on the nose pads and lenses. The Caravan features Square Sunglasses lenses and frames, as opposed to the teardrop lens shape sunglasses seen in the Aviator.
Selected reviews
Had exactly what I wanted at a great price. Email answered promptly. Delivery was extremely speedy. Overall a very satisfactory online purchase.
Always stock the sunnies your after at the best prices ever!
above say's it all really, other than the fact i have now brought the exact same pair 3 time's after dropping one pair off a very high balcony in Spa��
Perfectly executed transaction
Good quality and timely delivery. What else is there?


text:
Watch how to make this recipe.
Brine: In a large pot over medium-high heat, add the water, sage, thyme, lemon, salt, and peppercorns. Bring to a boil, then lower the heat and simmer until the salt is dissolved, and the water is fragrant. Turn off the heat and let the brine cool. Put the turkey in a roasting bag, a large plastic bag, or a bowl large enough to fit it with space for the brine. Pour in the brining liquid and seal or cover. If there is not enough room for all of the liquid in the brine, be sure to at least include the herbs, lemon and peppercorns. Refrigerate the turkey for up to 3 days. When ready to cook, remove the turkey from the refrigerator and discard all of brining liquid and solids. Pat the turkey dry with paper towels.
In a small bowl, mix the marjoram, sage, all the peppers, and salt to make the rub. Rub on all sides of the turkey, and drizzle with oil. Stuff the thyme, sage, and rosemary into the cavity, along with 4 of the garlic cloves, and 1 of the red onion quarters. Allow it to sit on the countertop for about 2 hours to come to room temperature.
Preheat the oven to 400 degrees F.
Put the remaining 2 garlic cloves, red onion quarters, and broth in the bottom of a roasting pan. Put the turkey on a rack in the roasting pan. Tuck the wing tips under and tie the legs together with butcher's twine.
Put the turkey in the oven and lower the heat to 350 degrees F. Roast, basting every 30 minutes, until an instant-read thermometer inserted between the thigh and the body registers 160 degrees F, about 2 to 3 hours. Add more broth to the bottom of the pan so the drippings do not burn. Allow the turkey to rest under loosely tented aluminum foil for about 10 minutes. Remove the turkey from the pan to a cutting board. Arrange the carved turkey on a serving platter and serve with Quick Pan Gravy.
Put the roasting pan on the stove top. Remove any large solids, like onions or stalks of rosemary, leaving only the pan drippings, softened garlic cloves, juices and fat. Turn the burner to medium-high heat and add the wine. Using a wooden spoon scrape up all bits from the bottom of the roasting pan. In a small bowl, mix together the flour and butter. Add it to the pan, breaking it up with a wooden spoon, while stirring. Cook for about 1 minute, and then whisk in the turkey broth and stir until thickened, about 5 minutes. Season with salt and pepper, to taste, and pour it into a serving bowl.
Check Out Our
Get a sneak-peek of the new Food Network recipe page and give us your feedback.See it Now!


text:
Is this political bluff or gotcha?
Apparently we're about to find out now that President Obama has chosen widely respected Merrick Garland as his nominee to replace the late Antonin Scalia on the Supreme Court.
(Read: Who is Merrick Garland?)
When Scalia died, Senate Republicans vowed not to consider any replacement nominated by Obama. The next president should get to fill that post, they argue.
Before a luncheon in Washington, D.C. last Friday, the conservative website Newsmax asked Sen. Orrin Hatch, R-Utah, for his thoughts on the Supreme Court situation.
Do you think Obama will nominate a black or Hispanic judge to make it more difficult for the Republicans to say no to a replacement during an election year, Newsmax asked him?
"He could be headed in that direction," said Hatch. "This (nomination process) is all about the election.
"The President told me several times he's going to name a moderate (to fill the court vacancy), but I don't believe him.
"(Obama) could easily name Merrick Garland, who is a fine man. He probably won't do that because this appointment is about the election. So I'm pretty sure he'll name someone the (liberal Democratic base) wants."
Game on.
In his Wednesday morning announcement, Obama quoted past praise for Garland from both Chief Justice John Roberts and Hatch, a long-time supporter of the appeals court judge.
In 2010 when Garland was considered for the Supreme Court post that eventually went to Sonia Sotomayor, Hatch called Garland a "consensus nominee" who would unquestionably be confirmed if nominated.
"The Garland nomination ... appears to be an attempt to box in Senate Republicans who've refused to confirm anyone Obama nominates," the progressive news blog ThinkProgress wrote on Wednesday.
"There are strong reasons to doubt whether this strategy will work, however. Sen. Hatch, who undoubtedly regrets his decision to praise Garland shortly before this nomination, has outright refused to meet with anyone Obama nominates to replace Scalia."
Hatch's previous support for Garland as a Supreme Court justice was also referenced in a four-page document circulated Tuesday afternoon among a small group of Obama allies, according to The Washington Post.
"Garland has had a distinguished legal career, and prior to the GOP's historically unprecedented obstruction, was a favorite of Senate Republicans alongside progressives," the briefing document said.
"When earlier Supreme Court vacancies occurred in the seats now filled by Justices Elena Kagan and Sonia Sotomayor, Utah Sen. Orrin Hatch said he would be 'very well supported by all sides' as a SCOTUS nominee."
Reaction to Garland's nomination is largely mixed, ranging from political observers calling him a "sensible" choice to Republican lawmakers saying "we'll take a meeting with him."
And comic book fans were happy to hear that he is one of them.
(See reaction from Missouri and Kansas lawmakers here.)
The American people deserve a say in the future of the #SupremeCourt. We have a chance to decide in Nov. Let the people's voices be heard.— David B. McKinley (@RepMcKinley) March 16, 2016
The history is also clear. The Senate has taken action on every Supreme Court nominee in the last 100 years. #DoYourJob— Senator Bob Casey (@SenBobCasey) March 16, 2016
Damn right. We the people have the right to a fully staffed Supreme Court... despite our political differences. https://t.co/HJd7hJipvP— Ian E. Savage (@iesavage) March 16, 2016
News Marvel - OBAMA's SUPREME COURT NOMINEE Is a Comic Book Fan... Or Was?: Merri... https://t.co/ThUudve8qH Deals:https://t.co/bi3ak01kZe— Marvel heroes (@Univers_Marvel) March 16, 2016
Some people think Obama wasted a chance to add more women, and racial diversity, to the court.
DemocracyForAmerica: Deeply disappointing PresObama failed to use oppty to add the voice of progressive woman of color to the Supreme Court— Shannon Bream (@ShannonBream) March 16, 2016
If you want the Supreme Court to be fair, you need a fair representation of society which would round up to 5 women, 4 men. Period.— Emu (@Emucratic) March 16, 2016
Prayers of an Indian village go unanswered with Supreme Court nomination https://t.co/bMJMAGSwZY— William Mungall (@WilliamMungall) March 16, 2016
"President Barack Obama's nomination of Merrick Garland to the Supreme Court is extremely disappointing," writes Mark Joseph Stern for Slate.
"Garland ... is about as mainstream as they come: a white, Harvard-educated Chicago boy who bounced between white-shoe firms and the Justice Department before President Bill Clinton placed him on the D.C. Circuit in 1997. Garland is the type of Washington elite who could've been placed on the court at almost any time over the past century."
National Organization for Women President Terry O'Neill praised Garland for " a rigorous intellect, impeccable credentials, and a record of excellence."
But she also said his record on women's rights was "more or less a blank slate. Equally unfortunate is that we have to continue to wait for the first African American woman to be named. For this nomination, the so-called political experts ruled that the best choice for the highest court in the nation was a cipher — a real nowhere man."
Politico reported that a handful of Senate Republicans said they would meet with Garland.
New Hampshire Sen. Kelly Ayotte, facing a tough reelection campaign, said she would use the meeting to explain face-to-face why she opposes naming anyone to replace Scalia before a new president is elected.
"He's a current appeals court judge and out of courtesy and respect we will certainly meet with him if he would like to meet with me," Ayotte told Politico.
"I would want to explain my position to the nominee ... I would want to give him that courtesy."


text:
The wiki for our iGEM team. iGEM is a synthetic biology competition, and as part of the competition each team must create a 'wiki' website to showcase and promote their project. Out of a pool of 54 teams, our team finished third overall in addition to winning the Best Wiki award.
The website for a three-day golf tournament our school hosted. The scoring integrates with a Google Spreadsheet and a SQLite backend, which automatically ranks the players and creates the leaderboard.
A single-page responsive website promoting the Formosa Film Festival. FFF holds monthly film challenges in addition to the festival in April, and the website showcases prior winners and gives submission information.
The events page for a debate competition our school hosted in March. Like other events sites, the website shows the schedule, results, and photos/video from the competition. Hosted on Google App Engine.
The events page for a soccer tournament.
The events page for a softball tournament.
The onboard control board for our underwater robot. ARM Teensy controller talks to motor drivers, sensors, cameras, and the onshore joystick. Communicates with RS485, I2C, and TTL serial. More details here.
An 8-channel motor driver that was designed for the ROV but can be used independently as a module. Communicates with I2C. Each channel has 5A capability and fault-reporting. More details here.
The onshore control board for the 2013 ROV. Interfaces with a PS2 joystick, 30A current sensor, an LCD, and a temp probe.
A remote battery-powered weather station that logs climate data. It is powered by a lithium battery that is recharged with a small solar cell. More details here.
This board was designed to drive a 32x24 LED matrix display. The controller multiplexes each row of the display through MBI5026 constant-current drivers. More details here.
A simple breakout board for the Lassen iQ GPS module.
This board was designed for a high-altitude balloon project, but was never put into use.
Shot in slow motion with a Sony FS7 and 85mm / 35mm prime lens. Edit, speed ramping, and basic grading done in Premiere. More details here.
Shot in slow motion with a Sony FS7 and 85mm / 35mm prime lens. Edit, speed ramping, and basic grading done in Premiere. More details here.