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Step 1: Apply Online
Step 2: Access your MJC Email
Step 3: College Orientation
Step 4: Assessment Testing
Step 5: Education Plan
Step 6: Official Transcripts
Step 7: Apply for Financial Aid
Step 8: Register for Classes
Step 9: Pay Fees
Contact the friendly Admissions Office staff if you have questions about adding or dropping classes, or filing for pass/no pass.
The Assessment Testing Office administers tests to help you select appropriate courses or satisfy pre-requisites.
International students should start by visiting our Information for International Students.
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Research and Planning has many data visualizations and drill-down reports that may fulfill your data needs. From topics of course success rates, to freshmen demographics, they can all be found in the Data Dashboards.
If you have a data need beyond our published reports, or dashboards, please send us a Data Request, and we'll endeavor to supply you as soon as possible.
Student Scorecard
The data available in this scorecard tell how well colleges are doing in remedial instruction, job training programs, retention of students and graduation and completion rates.
Please note: This scorecard uses data definitions that are likely different than internal or other reports. The data found here should not be used in comparison to data from other sources. The standardization of definitions found here does allow for comparisons between all community colleges.
Our featured visualization showcases one of our Data Dashboard Visualization; interactive reports that allow for filtering to specific groups, courses, or demographics.
Persistence Rates for First Time Freshmen
Through this visualization, you can select a specific starting year of incoming freshmen, or focus on ethnicity, or gender. Then by using the Education Plan, or Major filters, you can track their persistence (returning year after year) to completion.


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Police said a woman will not face charges for throwing a dog at an officer during a domestic violence investigation. Police Capt. Davidsaver said officers were called to southeast Lincoln for a report of domestic violence late Monday. He said the woman was suspected of throwing a cell phone that hit her boyfriend in the face.
Police said the woman was holding a small dog when officers arrived, and at some point, she threw the dog, named Flash, at an officer. Police said neither the dog nor the officer were injured.
The woman was arrested on suspicion of domestic assault.
Information from: KOLN-TV, http://www.kolnkgin.com

subset: commoncrawl


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Tuesday, 20 July 2010
History and interpretation
Crowe clearly explains FS history as following the series of interpretations: you try to trace their sequence and find out what was going on. See his "Theology and the Future: Responsible Innovation," Frederick E. Crowe, Appropriating the Lonergan Idea, ed. Michael Vertin (Washington, DC: Catholic University of America Press, 1989) 269.
Posted by Ivo Coelho at 03:24
Labels: Crowe, history, interpretation, Lonergan
Subscribe to: Post Comments (Atom)


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PERTH AMBOY — Raritan Bay Medical Center Foundation will hold its premier fundraising event for Raritan Bay Medical Center, the 28th Annual Harbor Lights Ball, Saturday, Sept. 29, at the Renaissance Woodbridge Hotel.
This year's theme is "Cirque du Santé" and will include music by Tim McLoone & the Shirleys, cirque performers, dancing and a grand auction. Proceeds from the ball benefit the medical center's "Broadening Our Vision, Securing Our Future" a construction and renovation project. This project will improve the availability of a diverse range of outpatient services, support emergency medical services, renovate patient rooms at Raritan Bay Medical Center's Old Bridge and Perth Amboy campuses and construct a new ambulatory surgical center at the Old Bridge campus.
If you would like more information about the Ball or to receive a formal invitation, contact the Foundation at 732-324-5374 or visit www.rbmcfoundation.org.
Each year's gala honors individuals for their dedication and philanthropic commitment to the medical center and surrounding communities. The 2012 awards and honorees are: Humanitarian Award – Gregory M. Ficarra, Woodbridge Township Council President and former director of health, physical education, nursing & athletics at Perth Amboy public school system; Executive of the Year Award – Deborah L. Tripod, president of Englert, Inc. of Perth Amboy; Excellence in Healthcare Award – member of RBMC's medical staff, Mark L. Niemiera, MD; Norman Tanzman Award – John "Jack" and Carol Hila. Jack was former Deputy Attorney General, Outside Counsel to the Department of Transportation, a Woodbridge Township Councilman and a trustee of the George Street Playhouse. Carol is president of Woodbridge Metropolitan Chamber of Commerce; and Future Leader Award – Vanessa E. Mendez, director of strategic initiatives, Tropical Cheese of Perth Amboy.
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I decided to get a start on my Christmas cards and was trying to think a little out of the box. This is a gate fold card with a window. Here is how it can be designed in Cricut Craft Room.
Sunday, 15 July 2012
First Christmas Card - Gatefold card
I decided to get a start on my Christmas cards and was trying to think a little out of the box. This is a gate fold card with a window. Here is how it can be designed in Cricut Craft Room.
52 comments:
Beautiful card.ReplyDelete
Thanks so much.Delete
This is beautiful. Love the embossing on pearlascent paper!ReplyDeleteReplies
Hi Pam - thanks.Delete
Karon! Another job WELL done! This is beautiful! I feel bad that I don't always make it over here with every post - but please know that all of your projects are lovely and I would be oh so lucky to be on the receiving end of them. Keep up the great work!!ReplyDeleteReplies
Thanks so much Ian - I do appreciate the time you take to visit and leave such lovely comments.Delete
Lovely card Karon. Art Philosophy is one of my favorite cartridges! Thanks for playing along with us at Go Fish!ReplyDeleteReplies
Thanks for commenting:-)Delete
Love how your card turned out. Beautiful job on the embossing too. Thank you for joining us over at GoFish! Challenge.ReplyDelete
Thanks Kate - appreciate it.Delete
This is beautiful Karon I love how you've designed the gatefol with a cicular aperture, Congratulations on your new DT position!ReplyDelete
Julie xReplies
Thanks Julie - you can use any symmetrical shape:-)Delete
Gorgeous card!!! The fold is fabulous and the entire design rocks!!ReplyDeleteReplies
WOW, thanks Pryn. What a lovely comment. TFLDelete
your card is so pretty. I just love the color and the embossing. Your card is so elegant and the stocking is just the cutest.ReplyDelete
Thank you for joining my DL.ART Thankful Thursday Christmas in July challenge.
Thanks Diana - I appreciate you stopping by and taking the time to comment.Delete
Great card, I love the fun fold to this one, and the colours.ReplyDeleteReplies
Thanks TracyDelete
Another great card and tutorial. Thank you for sharing!!ReplyDelete
Thanks Susie - appreciate the comment.Delete
Pretty gatefold card! I saw your card at MIM!ReplyDelete
Thanks for stopping by.Delete
You are so clever, Karon! This is such a cool card-- I think you have inspired me to try this shape-- love the peek-a-boo center!ReplyDeleteReplies
Thanks so much for leaving such a lovely comment.Delete
Great card Karon...Love it!!!ReplyDelete
What a great first design team post too :)
Welcome to the DT
Huge hugs
Thank you so much Adele - I really appreciate the support and lovely comment.Delete
oh Karon, this is gorgeous!! the embossing is beautiful on this design!!ReplyDelete
WOW Maria - thanks for the lovely comment.Delete
Adorable card- I love the embossing and the cut out! Thanks for playing at Go Fish Challenges! :)AmyReplyDeleteReplies
Thanks so much.Delete
How neat! I love the gate fold and the rich colors. Great job and thanks for playing at the Go Fish Challenge!ReplyDeleteReplies
Thanks for popping in.Delete
No not mad, well organised! It's lovely Karon, gatefold is a nice change as well. I'm midst washing (waist high ha ha) so having a coffee break. Can't see a crafting slot today boo hoo but getting sorted has to take first place.ReplyDeleteReplies
Thanks P, is that you back from hols? Hope you had a relaxing time, albeit a bit wet:-( HugsDelete
Hello. I popped by from MIM to see this beautiful card..LozReplyDeleteReplies
Thanks for stopping by today.Delete
Hi there! Saw you on MIM. WOWZERS! Just wanted to let you know I have blog candy if you're interested. :)ReplyDelete
My Blog CandyReplies
Thanks for stopping by Jenny.Delete
Fantastic texture! I saw your link at MIM. I'm #82 this week, I'd love it if you stopped by.ReplyDelete
Kasey ~ in OzReplies
Hi Kasey - thanks so much for visiting. and I popped in:-)Delete
Beautiful card. Thank you so much for joining the Creative Inspirations Paint challenge.ReplyDeleteReplies
Thanks so much for popping in.Delete
hi Karon... saw your card in MIm... wow... love it... very elegant and pretty cool pattern... love the way you filled in the detailing work...:)ReplyDeleteReplies
Thanks so much for commenting:-)Delete
I saw your beautiful creation on Make It Monday and had to come visit and take a closer look. Gorgeous! TFS! My entries are: #89, #90, #91, #151, #154, #155, #173, #254 and #255.ReplyDelete
I would love to have you visit my blog!
Thanks for popping in today, I went and visited too your cards are lovely.Delete
This is such a gorgeous card for Christmas. Love the beautiful embossed background. Your tutorial is great! Thank you so much for joining us at Make It Monday this week... :)ReplyDeleteReplies
Thank you so much for taking the time to come and visit.Delete
Beautiful card. Wonderful idea to add the window to a gatefold card. Thanks for sharing your art in the Creative Inspirations Paints blog challenge.ReplyDeleteReplies
Thanks - I appreciate the lovely comment.Delete
I saw your card at MIM and loved it, what a gorgeous card. Good luck in the challenge. JOxReplyDeleteReplies
Thanks so much for visiting today.Delete
I would like to thank you for stopping by my blog today. All your comments are really appreciated. Happy crafting everyone and have a great day.


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Articles with keyword "Digital Humanities Implementation Grants"
2016 NEH Office of Digital Humanities Project Directors Meeting-- Open to the Public
Join us for the 2016 NEH Office of Digital Humanities Project Directors' Meeting on September 16th, featuring lightning round presentations from our grantees and a keynote address from the digital initiatives team of the DC Public Library!
Announcing 8 Digital Humanities Implementation Grant Awards (August 2016)
The Office of Digital Humanities is happy to announce 8 awards from our Digital Humanities Implementation Grant program.
Update: ODH Support for Crowdsourcing in 2015
In 2015, the Office of Digital Humanities supported important work to engage wide audiences in crowdsourcing the humanities.
Updated Guidelines for Digital Humanities Implementation Grants
A few changes to the 2016 Digital Humanities Implementation Grants program guidelines.
Project Director Q&A: Immigrant Stories
Funded by a Digital Humanities Implementation Grant, researchers at the University of Minnesota are scaling up an initiative to create, collect, and share stories from recent immigrants and refugees to the United States.
ODH Project Director Q&A: Mary Flanagan
An interview with Mary Flanagan, director of Tiltfactor Lab at Dartmouth and leader of the ODH-funded Metadata Games project, an open-source platform for crowdsourcing cultural heritage.
A Change in our Implementation Grant Guidelines
This year, we have made one substantive addition to the guidelines: a special call that asks applicants to re-envision past work in innovative and ambitious ways.
Announcing Seven Digital Humanities Implementation Grants (July 2014)
The Office of Digital Humanities is happy to announce seven awards from our Digital Humanities Implementation Grants program from our February 2014 deadline.
ODH in the News
Several projects funded by NEH's Office of Digital Humanities have been featured in the news recently. Some highlights include articles on acoustic modeling of John Donne's sermons, mapping "infectious texts" from historic newspapers, the history of disease in a cross-cultural and geographically diverse set of mummies, and a profile of digital approaches to the 18th century "Republic of Letters."
Announcing 6 Digital Humanities Implementation Grant Awards (July 2013)
The Office of Digital Humanities is happy to announce 6 awards from the second round of our Digital Humanities Implementation Grants program from our January 2013 deadline.


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Simulating Gas Turbine Engines – Part 2: Rotating Systems
Location: Online
Date: Tuesday, April 1, 2014
10am (London) • 11am (Berlin/Paris) • 3:30pm (Bangalore)
10am (Los Angeles) • 1pm (New York)
In order to continually increase the performance and efficiency of their gas turbine (GT) engines, companies are seeking to operate their GT rotating systems at ever higher pressures and temperatures. This webcast will explore using numerical simulation to enable more predictive engineering of gas turbine engine rotating systems (i.e., turbines or compressors), especially to:
Increase GT performance and efficiency
Maximize GT reliability and up-time
Find better designs faster
The webinar will feature Rene Braun of B&B AGEMA as a guest presenter. Rene will discuss how B&B AGEMA uses simulation in the design of gas turbine engines to produce more efficient and reliable machines.
About B&B-AGEMA:
B&B-AGEMA in Aachen, Germany, was established as a competence center for power plant and turbomachinery technology. As experts in the design, development and testing of gas turbine engines, engineers there are working at the leading edge in their application of numerical simulation.
Their goal is to work on innovative design strategies that will be included in GT engines ~5 years from now. In this presentation, they will share some of their turbomachinery R&D work, including examples of how they have validated CHT in STAR-CCM+ and used it to improve the cooling techniques of several gas turbines.
More information and registration: www2.cd-adapco.com/l/14592/2014-02-11/654j5
Event Type: Webinar
Location: Online
Date: April 1, 2014


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5 Weeks to Hire
January 10, 2018 by Danya Proud
How to Speed Your Hiring Process in 3 easy steps!!Read More
January 10, 2018 by Danya Proud
How to Speed Your Hiring Process in 3 easy steps!!Read More
January 4, 2018 by Dan Lee
Everything we want is on the other side of fear. How to make 2018 the year you face Career Fears… one step at a time.Read More
August 1, 2017 by prtalent
Salaries are trending up for PR and MarCom positions across the country. This is PR Talent's assessment of where they stand today.Read More
July 19, 2017 by prtalent
Salaries are trending up for PR and MarCom positions across the country. This is PR Talent's assessment of where they stand today.Read More
May 6, 2017 by prtalent
So if there is no financial incentive, when does this get real for agencies and companies? Only when consumers pressure brands, and brands in turn pressure their marketing teams and agencies.Read More
December 24, 2016 by prtalent
Here are Six Hiring Trends in Communications for 2017…Read More
September 1, 2016 by prtalent
Why don't we put the energy and effort into mapping out a personal game plan for our careers and treat ourselves just like one of our clients?Read More
July 1, 2016 by prtalent
Salaries are trending up for PR and MarCom positions across the country. This is PR Talent's assessment of where they stand today.Read More
March 12, 2016 by prtalent
Salaries are trending up for PR and MarCom positions across the country. This is PR Talent's assessment of where they stand today.Read More
March 20, 2015 by prtalent
Salaries are trending up for PR and MarCom positions across the country. This is PR Talent's assessment of where they stand today.Read More
August 19, 2014 by prtalent
Technology is disruptive. And nothing before has disrupted like the Internet. Every day living is different. The way we shop, vacation, date, and most profoundly how we communicate with each other has changed. And of course the impact on communications piece has fundamentally changed public relations. It's what we do. PR practitioners serve as advocates for their clients by leveraging communications […]Read More
June 3, 2014 by angelsmith
OK… that was a little mean. There is no secret… no step-by-step formula. But there is a mix of art and science in the process.Read More
March 24, 2013 by prtalent
This is not a list of Wine Spectator 90 plus point wines… more like a list of whines from a spectator of candidate and client missteps over the last 90 plus years of my recruiting and PR career. Here we go… 1) Why do some candidates not list their clients in their resume? I can't think of a reson why you […]Read More
October 30, 2012 by angelsmith
Aside from offering a really handy way to scoop up two or three donuts at one time, a "donut hole" has been recently used to reference the insurance coverage gap found in Medicare.Read More
August 9, 2012 by angelsmith
Niche is in… especially when it comes to matchmaking. We've seen the evolution of dating sites go from eHarmony and Match.com to sites that match by religion — Jdate and ChristianMingle — to sites that now match by occupation. Farmers Only anyone?Read More
March 27, 2012 by angelsmith
Your resume can be arranged in one of two basic formats: chronological or functional… also sometimes referred to as a summary resume. The functional (or summary) resume distills your total work experience into major areas of expertise. For public relations this can be broken up into specific communications skills and industry expertise. The chronological resume […]Read More
September 2, 2015 by prtalent
PR Talent adds Danya Proud, former McDonald's Director of Communications, to lead Chicago and Midwest operations.Read More
January 9, 2014 by prtalent
Salaries are trending up for PR and MarCom positions across the country. This is PR Talent's assessment of where the stand today.Read More
November 26, 2013 by angelsmith
On almost every candidate call I'm asked "how's business" or "what's the hiring picture look like?" Often with a concerned tone like… it must be hell to be a recruiter for PR jobs in this economy?!? I reply by saying that hiring has been steady and trending up since early 2010. And that's the truth. Why?There are three sectors of […]Read More
February 3, 2013 by prtalent
Getting into the spirit of things for the upcoming State of the Union address (I've already hung the red, white and blue bunting which I normally reserve for when the Yankees are in the World Series) here are a few ramblings on the State of the PR Industry for 2013… The hottest coupling in Hollywood. The beautiful marriage of digital […]Read More
January 17, 2013 by prtalent
HUNTINGTON BEACH, Calif. — PR Talent, the nation's largest PR specialist recruiting firm, has added Angie Graf, as VP of Bay Area and Northwest Recruiting and Sheri Scott, as VP of Chicago and Midwest Recruiting. "We believe that having recruiters on the ground in key markets is the best way to understand that region's unique […]Read More
July 20, 2012 by angelsmith
PR Talent's boards also offer candidates career coaching, resume writing services, and the ability to set up personal job alerts. In addition, the job boards are members of the Marketing, Technology, and Healthcare Job Board Networks, enabling PR Talent clients to quickly post a single job to more than 500 other job boards — including other public relations job boards — at a highly discounted rate.Read More
February 27, 2012 by nikitasdavis70
My views on this topic are based on my years of recruiting experience in the PR industry and many conversations with people who have made the move from agency to client side. The decision to make a move from agency to client side depends on where you are in your career and what you are […]Read More
January 21, 2012 by angelsmith
At PR Talent, we've never done a salary survey before…. and I'm not about to start now! Market research has never been my strength and the thought of hiring some independent researcher to pull together an exhaustive survey that delivers only quasi-useful information is not my idea of fun. On the other hand, after 14 […]Read More
November 18, 2011 by angelsmith
HUNTINGTON BEACH, Calif. — PR Talent has announced the opening of a London office to handle executive search for full-time and freelance public relations positions. London is the first international office for the world's largest PR specialist recruiting firm. Diane Alexis, PR Talent's VP of International and Eastern Region U.S. Recruiting, will lead the office. […]Read More
October 8, 2011 by angelsmith
Not since Michael Jackson have we seen such an outpouring of heartfelt sympathy and appreciation for a public figure. It seems the overwhelming sentiment is that Steve Jobs and his creative mind really changed the way Americans interact on a daily basis. But did he really? He didn't invent anything that really changed the way we […]Read More
February 24, 2011 by angelsmith
When it comes to their careers, most people don't have a clue. They don't have a plan, a roadmap, a flashlight or even a Thomas Guide. They simply keep plowing forward, head down and hand out for the next paycheck. My guess is that a majority of people in PR put more thought into the […]Read More
September 8, 2010 by angelsmith
In my July post I talked about the growing demand for public relations talent along with the growing time to hire talent. As we head toward mid-September both trends are continuing and as the supply of PR talent diminishes we may see the time to hire window reverting back to the 6-8 weeks timeframe of a couple […]Read More
July 2, 2010 by angelsmith
Yes…. and No. Some people are hiring but they're taking their time. In PR, the average interview to hire timeframe is now 12-16 weeks v. 6-8 weeks from 2 years ago. But that's good news…. people are hiring in PR and it's mostly due to the increased demand for public relations professionals with social media experience. Clearly PR […]Read More
January 5, 2010 by angelsmith
OK. So it's a new year. Same as the old year? I don't think so. This year there's a palpable sense that people want to do business. They want to quit wringing their hands and take some risks. Make some decisions and actually get stuff done. I think everyone's tired of the woe is me, […]Read More
July 1, 2009 by angelsmith
As more and more talented folks find themselves thrust into the role of an accidental entrepreneur… suddenly starring in their own start-up… here are some tips I've learned over a few recessions. I also invite even better insights from other accidental entrepreneurs. 1. Prioritize Skills. Brand You is an overused term but it is a good descriptor in this context. As a new […]Read More
June 3, 2009 by angelsmith
Times are tough for candidates. Layoffs abound, jobs are in short supply, and competition for the few available openings is intense. Candidates are looking for allies and are reaching out to recruiters like never before. But recruiters are not easy to reach. Why? They've got lots of candidates but few jobs. The pendulum has swung and recruiters need to focus most […]Read More
May 28, 2009 by angelsmith
Agency budgets are being cut but the workload is not diminishing for most public relations departments as much of the burden is being shifted to an ever-leaner — and literally meaner — in-house staff. Over the past few years PR has done a good job at grabbing a significant share of the social media pie, […]Read More
May 20, 2009 by angelsmith
Nearly everything written about resume design concentrates on what you should put in. But let's look at what should be left out, or at least minimized. Salary history or salary requirements. I've never heard one good reason to mention your past, current, or expected salary. If you see a classified ad that says, "Only resumes […]Read More
May 15, 2009 by angelsmith
First of all there are no rules any more. But we do have some strong suggestions… especially if you're sending your resume to PR Talent. Brand You. Remember that your resume is summarizing your professional abilities as concisely and persuasively as possible. It's 'Brand You' on paper. Make sure that everything you put in your […]Read More
May 6, 2009 by angelsmith
In 1998, McKinsey published The War for Talent, a landmark study that predicted a white-collar talent shortage as large numbers of Baby Boomers marched off into retirement between the years 2000 and 2015. What McKinsey didn't forecast was today's economic crisis that diminishes these jobs, while simultaneously adding to the ranks tens of thousands of […]Read More


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I'm gonna put my hands up straight away and admit that I really wasn't all that into Tame Impala at first. To me, they were just another white, dull and boring indie band that made music for that exact demographic (probably why no one I know has heard of them, then). For quite some time I categorized them with the likes of DIIV, The War On Drugs and Kurt Vile (I could go on and on) and never really felt compelled by the immense hype surrounding these acts by the likes of Pitchfork. Though I still profess that they are a dull indie band who I would most likely dislike on a personal level, I did really like Lonerism (dammit!). This was largely down to the strong psychedelic production drowning out Kevin Parker's dreary vocals and making their whole aesthetic a lot more interesting as a result (see "Elephant", their breakout track). I was pleasantly surprised when the band dropped "Let It Happen", one of my favorite tracks of 2015, a few months ago and thus made me interested to see how the new record would sound. With Currents, they have come through with a more synth-heavy sound which largely serves them well.
The record begins strongly with Let It Happen, an epic labyrinth of psychedelia which is as compliant with old school disco as it is surf rock, making it one of the band's more experimental moments. This sets the tone for Currents rather well (especially as minimal guitar use is a theme throughout the record) and as a result many of the album highlights are synth-heavy and different to the rest of the band's discography. The production is certainly where this album's strengths lie, this is most prominent on tracks like 'Eventually', where an orchestra of synths, sneers and crashing symbols create a cascading dream-like soundscape. Elsewhere the band return to their earlier sound with mostly successful results, a key example being 'The Less I Know The Better', where the groove is structured around an instant guitar hook and Cam Avery's impeccable bass. The band revisit their Lonerism sound once again on the track 'The Moment', which features one of the more distinctive and hook-laden melodies on Currents, despite not actually having a defined chorus as such.
Despite the many highs this record has, there are a fair few duds which hinder my overall enjoyment. It is evident from my earlier praise that I adore the production, this has always been my favourite thing about the band itself. My issue with not only this record but Tame Impala as a whole is Kevin Parker's weak and often grating falsetto. Unfortunately this is a vocal style which dominates the indie rock 'scene', hence why it is often so damn dull. When the production is strong, I can overlook weak vocals, but where the production is lackluster and the vocals are more prevalent, they can cross the line into insufferable. 'Disciples' is the biggest culprit of this, the fast pace of the track perhaps making Parker's voice sound extra whiny. But thankfully this track is only 2 minutes long so the suffering is not prolonged, the same cannot be said for 'Cause I'm a Man' which is easily one of the most indulgent, irritating and unappealing songs of their career thus far.
But believe it or not, I actually do quite like this record; It may not be as good as Lonerism, but it still hits far more than it misses. Let It Happen and The Less I Know The Better, both of which are career highlights, in particular ensure that the bad recover from misjudgments such as 'Cause I'm A Man and the awkward interludes. Overall I commend Kevin Parker and Co. for experimenting with the sound that broke them into the mainstream without alienating their older fans, which is somewhat of a rarity in the industry today.
Best tracks: Let It Happen, The Moment, Eventually, The Less I Know The Better


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Current & Upcoming Exhibitions
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Apr. 28, 2018 — Jun. 24, 2018
Celebrating Libbey Glass, 1818-2018
May. 4, 2018 — Nov. 25, 2018
Coming SoonRebecca Louise Law: Community
Beginning June 16
Coming SoonFrans Hals Portraits: A Family Reunion
Beginning October 13


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Nick Offerman swung by Conan last night in his best Ron-Swanson-at-the-Woodworking-Awards attire last night and they discussed all things masculine: mustaches, man musk, handmade kazoos, and the little-something-for-the-philanthropic-ladies burlesque show that I must admit frightened the hell out of me (seriously, nipples in the wrong places are like a top five fear).
Of all the manly talk I must admit Nick clarifying his "People's Sexiest Man Alive" designation in the beginning of the first clip below was my favorite part as I plan to borrow "to be fair to my friend Channing" when I'm explaining to the ladies at Dunkin Donuts that I was named "Sexiest Man Alive: Internet Edition" in the magazine's lesser known online portion of the feature. "It's kind of like those Oscars they give out the night before The Oscars."
Also, WANT an Offerman Woodshop kazoo like yesterday.
We were all thinking exactly what Andy said despite being unclear of the exact implementation.


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Get organised and create a personalised calendar with your special dates and memorable photos. Choose from different styles including desk and various wall calendars. You can even start your calendar in any month of your choosing
print page name : Calendars
print page url : /photo-gift/Calendars
dcr path:
isFooterOff : true
isFooterOff1 : false
isItAmazonCobrand : false


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Two researchers from 3CSEP, Veronika Czakó and Sergio Tirado-Herrero were interviewed as part of Duna TV's "Strangers in the greenhouse" Idegenek az üvegházban) series on climate change. Veronika Czakó talked about the possibilities of climate action at the level of local governments, while Sergio Tirado-Herrero explored issues related to buildings' energy efficiency in the Hungarian context.
For the interviews and the relevant episode of the TV series (in Hungarian), please follow the link:
Two recent European policy discussions on energy use featured input from Diana Urge-Vorsatz, Professor in CEU's Department of Environmental Sciences and Policy -- more specifically, with her research on the so-called "lock-in effect". This research is indicating that policy-makers and developers are potentially missing out on substantial long-term efficiency improvements, by focusing solely on low-hanging fruit in their approach to the environmental retro-fitting of buildings.
Presentations in Hungarian language are available on a dedicated subpage, please click here.
The Center for Climate Change and Sustainable Energy Policy had the pleasure to host a public lecture by internationally renowned Canadian climate change expert Danny Harvey from the University of Toronto on April 23, 2009.
The highly acclaimed talk highlighted some of the latest scientific evidence and observations indicating that global warming poses a grave threat to human well-being and ecosystems throughout the world.
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Build Guide by Lenor
Not Updated For Current Season
This guide has not yet been updated for the current season. Please keep this in mind while reading. You can see the most recently updated guides on the browse guides page.
Thank You!
Your votes and comments encourage our guide authors to continue
creating helpful guides for the League of Legends community.
Rammus Build
Ability Sequence
Not Updated For Current Season
The masteries shown here are not yet updated for the current season, the guide author needs to set up the new masteries. As such, they will be different than the masteries you see in-game.
I will try to keep the guide as short as possible,so here it goes:
You are useless if you get disabled and can't taunt the enemy DPS-er
Flash is very good for initiating team figths.Activate powerball and flash right in the middle of the enemy team.
We maximize Puncturing Taunt first because it's one of the best disables in the game.
Also we chose Defensive Ball Curl over Powerball because it's more useful in team fights.
One rank of Powerball is enough for chasing/escaping.
Start off withand aIt will keep you going for some time.
Play defensively,taunt when someone gets too close to your turret,get last hits and so on.
Gettingas soon as possible will help your team if you decide to go for an early push.
Next item should beI choose ninja tabi over the others because of the dodge it provides.
Now analize the enemy team,if they have more magic damage than phisical then getIf they have more phisical damage champions then get
But if they have a nasty DPS-er that gives your team trouble then you should grabbut only if you have trouble,because frozen heart gives you more useful stats
Next item should be the one you didn't get,if you got banshees veil then get frozen heart/thornmail,if you got frozen heart/thornmail...
Next get
If the game lasts until now then getas a finishing touch
Looking forward to answering any questions...
Good Luck!


text:
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Show Details
The ergonomic Stock Room Leveler from Retail Handling Solutions simplifies the job of unloading boxes from pallets, improving productivity, worker safety, and employee morale in supermarkets, pharmacies, convenience stores, and other retail outlets. It keeps loads at a comfortable height, saving time and reducing the risk of injury from the bending, lifting, reaching, and stretching common to unloading pallets.
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©2018 Retail Handling Solutions - 11 Gray Road, Falmouth, ME 04105
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The most promising federal work in using technology to reduce fraud and improper payments is being done by the Recovery Accountability and Transparency Board, he said, which is deploying open-source technology, data mining and source triangulation to "set the government on new path."
Werfel spoke at the leadership summit held at the Newseum by business intelligence software firm SAS, which brought together federal financial managers and vendors to explore how private sector analytics tools can enhance government decision-making.
He recounted several "transformational moments" in his long career at OMB that opened his eyes to the notion that financial management systems -- under the rubric of transparency and accountability -- have now become central to the policy process and to public trust in government.
At a 2005 financial forum led by then-Comptroller General David M. Walker, "there was palpable frustration," Werfel said, "that no one was reading our financial reports," or vesting themselves in the government's financial controls and risk mitigation. "There was an identity crisis in the chief financial officer community," he said.
Soon after that meeting, the Transportation Department lost its clean audit opinion, for minor reasons, Werfel said, which was a "traumatic experience for a multimillion-dollar organization." What was notable, however, was that the event received no press coverage and no inquiries from Congress. "But that same week, the Defense Department spent $60,000 on a tent for a retirement party," he recalled, and the mainstream media and Congress took up the cry. "That was my first data point, when I started to think seriously about whether a CFO's report can be impactful on citizens trust in government's management."
His next transformational event occurred when, during the final days of the George W. Bush administration, he watched as Treasury Secretary Henry Paulson drafted a bill of just three pages, asking Congress for $700 billion for what became the Troubled Asset Relief Program. "The response from Capitol Hill was, How dare they ask for all that with no transparency, accountability, audits, and bells and whistles?" Werfel said. "It was eye-opening that by now people were interested in what government is doing with finances and controls."
Werfel's third transformation came soon after when the fledgling Obama administration asked him to help write the legislation asking for another $700 billion that became the stimulus package known as the American Recovery and Reinvestment Act. "We knew that this time we wouldn't make the same mistake [Paulson did]," Werfel continued. "The Recovery Act was a validation of our data points, that how far controls in the intersection of political demand for public information and transparency and accountability controls took center stage."
Noting Vice President Biden's announcement on Monday that the Recovery Board's leader and methods for cutting government waste are being applied governmentwide, Werfel said agencies are getting better at creating infrastructure to track spending. "It's a real labor and a push, which shows how far we still need to go" in responding to the "growing call for more transparency and accountability" in federal spending, he said.
The Recovery Board's fraud detection center, Werfel said, shows that the government can be smarter about, for example, avoiding making payments to contractors who are suspended or debarred. He pointed to triangulating tools of data mining that raise such potential red flags as multiple corporations at the same headquarters or contractors with felony records. "Sometimes it's the naming convention that's off," he explained, noting that data mining can uncover that fact that "John Smith" and "John L. Smith" are the same person. Agencies can welcome this because it identifies such issues upfront without spending a dime, he said.
Some agencies, Werfel added, are skeptical that OMB and the Recovery Board have many tools to add to their own kits. But he proved his point when he supervised a pilot project at the Health and Human Services Department, which houses the government's "big fish" that specialize in medical claims fraud. "HHS is good at finding fraud in medical claims" by looking at geographic patterns, he said, "but they're not so good at identify theft, as when doctors steal licenses from doctors in other states and set up false billing practices."
The Recovery Board's data tools "sprung out an entire fraud ring right under HHS' nose," Werfel said. "I'm not saying the Recovery Board is always better, just that many agencies are not effectively deploying the technology. My mission is to gain momentum and make this stuff go viral as we roll in more agencies."
Werfel spoke of the need to cut the estimated annual $125 billion in improper payments, noting that sending checks to people who are incarcerated or otherwise ineligible "is shameful and embarrassing, and it's a headline-grabber." But it's difficult to mitigate, he said. When people die, the government doesn't get the information in real time -- it can take as long as 20 or 24 months to get the information "in the system," he said.
"But some [in government] have said they'd rather allow 100,000 payments to dead people than deny one legitimate claim. So we have to decide what policies we're willing to live with," Werfel said. "It's OK to do a data pull" and use a combination of technology and expertise to collaborate to perform the analytics, which can do the job efficiently" he said. But financial managers can't cut too deeply into the values issues. "We need to find a strategic balance between the tools and the policy decisions on what we're willing to live with, and know this upfront before we invest in them."


text: Hey there! My name is Denise Walsh and I am a Black Diamond with It Works! I've been in business for 10 years now and I absolutely love being a wrapreneur!! My husband, Brandon, and I were the second people to enter the "Millionaire's Club" & and we are officially the top recruiters in the history of It Works Global – and we're not slowing down any time soon! Over the years, It Works has created millions of s


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Media tagged with "Service"
Mission Critical Fire Safety
Article | Mission Critical (2014)
The data collection and cloud computing industry has seen tremendous growth in recent years, and that growth has been a boon to the construction industry, which is being called upon to design and build these structures to accommodate complex mechanical needs. Chief among these needs is a reliable and effective fire protection system that will ensure mission-critical technology like servers are always operational.
Southland Industries Establishes National Service Division
Union City, CA (2014)
Southland Industries, one of the nation's largest mechanical, electrical, and plumbing (MEP) building systems experts providing engineering, construction, service and energy service solutions, recently made the decision to unite its service and building automation controls departments into a single division, called Southland Service. Led by Executive Vice President Joe Cvetas, Southland Service will work to amplify the company's service and building automation offerings.
Springtime Cooling Tower Maintenance
Article | Buildings Magazine (2013)
Springtime cooling tower maintenance. Getting ready for the cooling season? Make sure you're covering all of your bases
Southland Industries Awarded Walter Reed Service and Maintenance Contract
Dulles, VA (2012)
Southland Industries was recently awarded the service and maintenance contract for the Building 9 Surgical Suite at the new Walter Reed National Military Medical Center (WRNMMC) in Bethesda, Maryland.


text:
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I will do this at the most minimum cost. Trust me by giving me the project I have expertise in .NET enterprise apps development. Relevant Skills and Experience .Net C# ASP.NET WCF WPF WIF WWF Proposed Milestones $30 More


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Logan Steel knows how expensive everything can be these days, which is why we always offer an alternative for our customers so everyone can get the job done at a reasonable price. We always offer the Bargain Barn which is $1.00/lb. and is open to all of our customers and we also have our Deal of the Week, which rotates specials that can be redeemed during the course of that week.
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The New Genetics
Chapter 2: RNA and DNA Revealed: New Roles, New Rules
For many years, when scientists thought about heredity, DNA was the first thing to come to mind. It's true that DNA is the basic ingredient of our genes and, as such, it often steals the limelight from RNA, the other form of genetic material inside our cells.
But, while they are both types of genetic material, RNA and DNA are rather different.
The chemical units of RNA are like those of DNA, except that RNA has the nucleotide uracil (U) instead of thymine (T). Unlike double-stranded DNA, RNA usually comes as only a single strand. And the nucleotides in RNA contain ribose sugar molecules in place of deoxyribose.
RNA is quite flexible—unlike DNA, which is a rigid, spiral-staircase molecule that is very stable. RNA can twist itself into a variety of complicated, three-dimensional shapes. RNA is also unstable in that cells constantly break it down and must continually make it fresh, while DNA is not broken down often. RNA's instability lets cells change their patterns of protein synthesis very quickly in response to what's going on around them.
Many textbooks still portray RNA as a passive molecule, simply a "middle step" in the cell's gene-reading activities. But that view is no longer accurate. Each year, researchers unlock new secrets about RNA. These discoveries reveal that it is truly a remarkable molecule and a multi-talented actor in heredity.
Today, many scientists believe that RNA evolved on the Earth long before DNA did. Researchers hypothesize—obviously, no one was around to write this down—that RNA was a major participant in the chemical reactions that ultimately spawned the first signs of life on the planet.
RNA World
At least two basic requirements exist for making a cell: the ability to hook molecules together and break them apart, and the ability to replicate, or copy itself, from existing information.
RNA probably helped to form the first cell. The first organic molecules, meaning molecules containing carbon, most likely arose out of random collisions of gases in the Earth's primitive atmosphere, energy from the Sun, and heat from naturally occurring radioactivity. Some scientists think that in this primitive world, RNA was a critical molecule because of its ability to lead a double life: to store information and to conduct chemical reactions. In other words, in this world, RNA served the functions of both DNA and proteins.
What does any of this have to do with human health? Plenty, it turns out.
Today's researchers are harnessing some of RNA's flexibility and power. For example, through a strategy he calls directed evolution, molecular engineer Ronald R. Breaker of Yale University is developing ways to create entirely new forms of RNA and DNA that both work as enzymes.
Breaker and others have also uncovered a hidden world of RNAs that play a major role in controlling gene activity, a job once thought to be performed exclusively by proteins. These RNAs, which the scientists named riboswitches, are found in a wide variety of bacteria and other organisms.
This discovery has led Breaker to speculate that new kinds of antibiotic medicines could be developed to target bacterial riboswitches.
Molecular Editor
Scientists are learning of another way to customize proteins: by RNA editing. Although DNA sequences spell out instructions for producing RNA and proteins, these instructions aren't always followed precisely. Editing a gene's mRNA, even by a single chemical letter, can radically change the resulting protein's function. Nature likely evolved the RNA editing function as a way to get more proteins out of the same number of genes. For example, researchers have found that the mRNAs for certain proteins important for the proper functioning of the nervous system are particularly prone to editing. It may be that RNA editing gives certain brain cells the capacity to react quickly to a changing environment.
Which molecules serve as the editor and how does this happen? Brenda Bass of the University of Utah School of Medicine in Salt Lake City studies one particular class of editors called adenosine deaminases. These enzymes "retype" RNA letters at various places within an mRNA transcript.
They do their job by searching for characteristic RNA shapes. Telltale twists and bends in folded RNA molecules signal these enzymes to change the RNA sequence, which in turn changes the protein that gets made.
Bass' experiments show that RNA editing occurs in a variety of organisms, including people. Another interesting aspect of editing is that certain disease-causing microorganisms, such as some forms of parasites, use RNA editing to gain a survival edge when living in a human host. Understanding the details of this process is an important area of medical research.
Small But Powerful
Recently, molecules called microRNAs have been found in organisms as diverse as plants, worms and people. The molecules are truly "micro," consisting of only a few dozen nucleotides, compared to typical human mRNAs that are a few thousand nucleotides long.
What's particularly interesting about microRNAs is that many of them arise from DNA that used to be considered merely filler material (see Getting the Message).
How do these small but important RNA molecules do their work? They start out much bigger but get trimmed by cellular enzymes, including one aptly named Dicer. Like tiny pieces of Velcro®, microRNAs stick to certain mRNA molecules and stop them from passing on their protein-making instructions.
First discovered in a roundworm model system (see Living Laboratories), some microRNAs help determine the organisms body plan. In their absence, very bad things can happen. For example, worms engineered to lack a microRNA called let-7 develop so abnormally that they often rupture and practically break in half as the worm grows.
Perhaps it is not surprising that since microRNAs help specify the timing of an organism's developmental plan, the appearance of the microRNAs themselves is carefully timed inside a developing organism. Biologists, including Amy Pasquinelli of the University of California, San Diego, are currently figuring out how microRNAs are made and cut to size, as well as how they are produced at the proper time during development.
MicroRNA molecules also have been linked to cancer. For example, Gregory Hannon of the Cold Spring Harbor Laboratory on Long Island, New York, found that certain microRNAs are associated with the severity of the blood cancer B-cell lymphoma in mice.
Since the discovery of microRNAs in the first years of the 21st century, scientists have identified hundreds of them that likely exist as part of a large family with similar nucleotide sequences. New roles for these molecules are still being found.
RNA Interference (RNAi)
Healthy Interference
RNA controls genes in a way that was only discovered recently: a process called RNA interference, or RNAi. Although scientists identified RNAi less than 10 years ago, they now know that organisms have been using this trick for millions of years.
Researchers believe that RNAi arose as a way to reduce the production of a gene's encoded protein for purposes of fine-tuning growth or self-defense. When viruses infect cells, for example, they command their host to produce specialized RNAs that allow the virus to survive and make copies of itself. Researchers believe that RNAi eliminates unwanted viral RNA, and some speculate that it may even play a role in human immunity.
Oddly enough, scientists discovered RNAi from a failed experiment! Researchers investigating genes involved in plant growth noticed something strange: When they tried to turn petunia flowers purple by adding an extra "purple" gene, the flowers bloomed white instead.
This result fascinated researchers, who could not understand how adding genetic material could somehow get rid of an inherited trait. The mystery remained unsolved until, a few years later, two geneticists studying development saw a similar thing happening in lab animals.
The researchers, Andrew Z. Fire, then of the Carnegie Institution of Washington in Baltimore and now at Stanford University, and Craig Mello of the University of Massachusetts Medical School in Worcester, were trying to block the expression of genes that affect cell growth and tissue formation in roundworms, using a molecular tool called antisense RNA.
To their surprise, Mello and Fire found that their antisense RNA tool wasn't doing much at all. Rather, they determined, a double-stranded contaminant produced during the synthesis of the single-stranded antisense RNA interfered with gene expression. Mello and Fire named the process RNAi, and in 2006 were awarded the Nobel Prize in physiology or medicine for their discovery.
Further experiments revealed that the double-stranded RNA gets chopped up inside the cell into much smaller pieces that stick to mRNA and block its action, much like the microRNA pieces of Velcro discussed above (see drawing).
Today, scientists are taking a cue from nature and using RNAi to explore biology. They have learned, for example, that the process is not limited to worms and plants, but operates in humans too.
Medical researchers are currently testing new types of RNAi-based drugs for treating conditions such as macular degeneration, the leading cause of blindness, and various infections, including those caused by HIV and the herpes virus.
Dynamic DNA
A good part of who we are is "written in our genes," inherited from Mom and Dad. Many traits, like red or brown hair, body shape and even some personality quirks, are passed on from parent to offspring.
But genes are not the whole story. Where we live, how much we exercise, what we eat: These and many other environmental factors can all affect how our genes get expressed.
You know that changes in DNA and RNA can produce changes in proteins. But additional control happens at the level of DNA, even though these changes do not alter DNA directly. Inherited factors that do not change the DNA sequence of nucleotides are called epigenetic changes, and they too help make each of us unique.
Epigenetic means, literally, "upon" or "over" genetics. It describes a type of chemical reaction that can alter the physical properties of DNA without changing its sequence. These changes make genes either more or less likely to be expressed (see drawing).
Currently, scientists are following an intriguing course of discovery to identify epigenetic factors that, along with diet and other environmental influences, affect who we are and what type of illnesses we might get.
Secret Code
DNA is spooled up compactly inside cells in an arrangement called chromatin. This packaging is critical for DNA to do its work. Chromatin consists of long strings of DNA spooled around a compact assembly of proteins called histones.
One of the key functions of chromatin is to control access to genes, since not all genes are turned on at the same time. Improper expression of growth-promoting genes, for example, can lead to cancer, birth defects or other health concerns.
Many years after the structure of DNA was determined, researchers used a powerful device known as an electron microscope to take pictures of chromatin fibers. Upon viewing chromatin up close, the researchers described it as "beads on a string," an image still used today. The beads were the histone balls, and the string was DNA wrapped around the histones and connecting one bead to the next.
Decades of study eventually revealed that histones have special chemical tags that act like switches to control access to the DNA. Flipping these switches, called epigenetic markings, unwinds the spooled DNA so the genes can be transcribed.
The observation that a cell's gene-reading machinery tracks epigenetic markings led C. David Allis, who was then at the University of Virginia Health Sciences Center in Charlottesville and now works at the Rockefeller University in New York City, to coin a new phrase, the "histone code." He and others believe that the histone code plays a major role in determining which proteins get made in a cell.
Flaws in the histone code have been associated with several types of cancer, and researchers are actively pursuing the development of medicines to correct such errors.
Genetics and You: The Genetics of Anticipation
Occasionally, unusual factors influence whether or not a child will be born with a genetic disease.
An example is the molecular error that causes Fragile X syndrome, a rare condition associated with mental retardation. The mutation leading to a fragile X chromosome is not a typical DNA typing mistake, in which nucleotides are switched around or dropped, or one of them is switched for another nucleotide. Instead, it is a kind of stutter by the DNA polymerase enzyme that copies DNA. This stutter creates a string of repeats of a DNA sequence that is composed of just three nucleotides, CGG.
Some people have only one repeat of the CGG nucleotide triplet. Thus, they have two copies of the repeat in a gene, and the extra sequence reads CGGCGG. Others have more than a thousand copies of the repeat. These people are the most severely affected.
The number of triplet repeats seems to increase as the chromosome is passed down through several generations. Thus, the grandsons of a man with a fragile X chromosome, who is not himself affected, have a 40 percent risk of retardation if they inherit the repeat-containing chromosome. The risk for great-grandsons is even higher: 50 percent.
Intrigued by the evidence that triplet repeats can cause genetic disease, scientists have searched for other examples of disorders associated with the DNA expansions. To date, more than a dozen such disorders have been found, and all of them affect the nervous system.
Analysis of the rare families in which such diseases are common has revealed that expansion of the triplet repeats is linked to something called genetic anticipation, when a disease's symptoms appear earlier and more severely in each successive generation.
Battle of the Sexes
A process called imprinting, which occurs naturally in our cells, provides another example of how epigenetics affects gene activity.
With most genes, the two copies work exactly the same way. For some mammalian genes, however, only the mother's or the father's copy is switched on regardless of the child's gender. This is because the genes are chemically marked, or imprinted, during the process that generates eggs and sperm.
As a result, the embryo that emerges from the joining of egg and sperm can tell whether a gene copy came from Mom or Dad, so it knows which copy of the gene to shut off.
One example of an imprinted gene is insulin-like growth factor 2 (Igf2), a gene that helps a mammalian fetus grow. In this case, only the father's copy of Igf2 is expressed, and the mother's copy remains silent (is not expressed) throughout the life of the offspring.
Scientists have discovered that this selective silencing of Igf2 and many other imprinted genes occurs in all placental mammals (all except the platypus, echidna and marsupials) examined so far, but not in birds.
Why would nature tolerate a process that puts an organism at risk because only one of two copies of a gene is working? The likely reason, many researchers believe, is that mothers and fathers have competing interests, and the battlefield is DNA!
The scenario goes like this: It is in a father's interest for his embryos to get bigger faster, because that will improve his offspring's chances of survival after birth. The better an individual's chance of surviving infancy, the better its chance of becoming an adult, mating and passing its genes on to the next generation.
Of course mothers want strong babies, but unlike fathers, mothers provide physical resources to embryos during pregnancy. Over her lifetime, a female is likely to be pregnant several times, so she needs to divide her resources among a number of embryos in different pregnancies.
Researchers have discovered over 200 imprinted genes in mammals since the first one was identified in 1991. We now know that imprinting controls some of the genes that have an important role in regulating embryonic and fetal growth and allocating maternal resources. Not surprisingly, mutations in these genes cause serious growth disorders.
Marisa Bartolomei of the University of Pennsylvania School of Medicine in Philadelphia is trying to figure out how Igf2 and other genes become imprinted and stay silent throughout the life of an individual. She has already identified sequences within genes that are essential for imprinting. Bartolomei and other researchers have shown that these sequences, called insulators, serve as "landing sites" for a protein that keeps the imprinted gene from being transcribed.
Starting at the End
When we think of DNA, we think of genes. However, some DNA sequences are different: They don't encode RNAs or proteins. Introns, described in Chapter 1, are in this category.
Another example is telomeres—the ends of chromosomes. There are no genes in telomeres, but they serve an essential function. Like shoelaces without their tips, chromosomes without telomeres unravel and fray. And without telomeres, chromosomes stick to each other and cause cells to undergo harmful changes like dividing abnormally.
Researchers know a good deal about telomeres, dating back to experiments performed in the 1970s by Elizabeth Blackburn, a basic researcher who was curious about some of the fundamental events that take place within cells.
At the time, Blackburn, now at the University of California, San Francisco, was working with Joseph Gall at Yale University. For her experimental system, she chose a single-celled, pond-dwelling organism named Tetrahymena. These tiny, pear-shaped creatures are covered with hairlike cilia that they use to propel themselves through the water as they devour bacteria and fungi.
Tetrahymena was a good organism for Blackburn's experiments because it has a large number of chromosomes—which means it has a lot of telomeres!
Her research was also perfectly timed, because methods for sequencing DNA were just being developed. Blackburn found that Tetrahymenas telomeres had an unusual nucleotide sequence: TTGGGG, repeated about 50 times per telomere.
Since then, scientists have discovered that the telomeres of almost all organisms have repeated sequences of DNA with lots of Ts and Gs. In human and mouse telomeres, for example, the repeated sequence is TTAGGG.
The number of telomere repeats varies enormously, not just from organism to organism but in different cells of the same organism and even within a single cell over time. Blackburn reasoned that the repeat number might vary if cells had an enzyme that added copies of the repeated sequence to the telomeres of some but not all chromosomes.
With her then-graduate student Carol Greider, now at Johns Hopkins University, Blackburn hunted for the enzyme. The team found it and Greider named it telomerase. Blackburn, Greider and Jack Szostak of Harvard Medical School in Boston shared the 2009 Nobel Prize in physiology or medicine for their discoveries about telomeres and telomerase.
As it turns out, the telomerase enzyme consists of a protein and an RNA component, which the enzyme uses as a template for copying the repeated DNA sequence.
What is the natural function of telomerase? As cells divide again and again, their telomeres get shorter. Most normal cells stop dividing when their telomeres wear down to a certain point, and eventually the cells die. Telomerase can counteract the shortening. By adding DNA to telomeres, telomerase rebuilds the telomere and resets the cell's molecular clock.
The discovery of telomerase triggered new ideas and literally thousands of new studies. Many researchers thought that the enzyme might play important roles in cancer and aging. Researchers were hoping to find ways to turn telomerase on so that cells would continue to divide (to grow extra cells for burn patients, for example), or off so that cells would stop dividing (to stop cancer, for instance).
So far, they have been unsuccessful. Although it is clear that telomerase and cellular aging are related, researchers do not know whether telomerase plays a role in the normal cellular aging process or in diseases like cancer.
Recently, however, Blackburn and a team of other scientists discovered that chronic stress and the perception that life is stressful affect telomere length and telomerase activity in the cells of healthy women. Blackburn and her coworkers are currently conducting a long-term, follow-up study to confirm these intriguing results.
The Other Human Genome
Before you think everything's been said about DNA, there's one little thing we didn't mention: Some of the DNA in every cell is quite different from the DNA that we've been talking about up to this point. This special DNA isn't in chromosomes—it isn't even inside the cell's nucleus where all the chromosomes are!
So where is this special DNA? It's inside mitochondria, the organelles in our cells that produce the energy-rich molecule adenosine triphosphate, or ATP. Mendel knew nothing of mitochondria, since they weren't discovered until late in the 19th century. And it wasn't until the 1960s that researchers discovered the mitochondrial genome, which is circular like the genomes of bacteria.
In human cells, mitochondrial DNA makes up less than 1 percent of the total DNA in each of our cells. The mitochondrial genome is very small—containing only about three dozen genes. These encode a few of the proteins that are in the mitochondrion, plus a set of ribosomal RNAs used for synthesizing proteins for the organelle.
Mitochondria need many more proteins though, and most of these are encoded by genes in the nucleus. Thus, the energy-producing capabilities of human mitochondria—a vital part of any cell's everyday health—depend on coordinated teamwork among hundreds of genes in two cellular neighborhoods: the nucleus and the mitochondrion.
Mitochondrial DNA gets transcribed and the RNA is translated by enzymes that are very different from those that perform this job for genes in our chromosomes. Mitochondrial enzymes look and act much more like those from bacteria, which is not surprising because mitochondria are thought to have descended from free-living bacteria that were engulfed by another cell over a billion years ago.
Scientists have linked mitochondrial DNA defects with a wide range of age-related diseases including neurodegenerative disorders, some forms of heart disease, diabetes and various cancers. It is still unclear, though, whether damaged mitochondria are a symptom or a cause of these health conditions.
Scientists have studied mitochondrial DNA for another reason: to understand the history of the human race. Unlike our chromosomal DNA, which we inherit from both parents, we get all of our mitochondrial DNA from our mothers.
Thus, it is possible to deduce who our maternal ancestors were by tracking the inheritance of mutations in mitochondrial DNA. For reasons that are still not well understood, mutations accumulate in mitochondrial DNA more quickly than in chromosomal DNA. So, it's possible to trace your maternal ancestry way back beyond any relatives you may know by name—all the way back to "African Eve," the ancestor of us all!
The Tools of Genetics: Recombinant DNA and Cloning
In the early 1970s, scientists discovered that they could change an organism's genetic traits by putting genetic material from another organism into its cells. This discovery, which caused quite a stir, paved the way for many extraordinary accomplishments in medical research that have occurred over the past 35 years.
How do scientists move genes from one organism to another? The cutting and pasting gets done with chemical scissors: enzymes, to be specific. Take insulin, for example. Let's say a scientist wants to make large quantities of this protein to treat diabetes. She decides to transfer the human gene for insulin into a bacterium, Escherichia coli, or E. coli, which is commonly used for genetic research (see Living Laboratories). That's because E. coli reproduces really fast, so after one bacterium gets the human insulin gene, it doesn't take much time to grow millions of bacteria that contain the gene.
The first step is to cut the insulin gene out of a copied, or "cloned," version of the human DNA using a special bacterial enzyme from bacteria called a restriction endonuclease. (The normal role of these enzymes in bacteria is to chew up the DNA of viruses and other invaders.) Each restriction enzyme recognizes and cuts at a different nucleotide sequence, so it's possible to be very precise about DNA cutting by selecting one of several hundred of these enzymes that cuts at the desired sequence. Most restriction endonucleases make slightly staggered incisions, resulting in "sticky ends," out of which one strand protrudes.
The next step in this example is to splice, or paste, the human insulin gene into a circle of bacterial DNA called a plasmid. Attaching the cut ends together is done with a different enzyme (obtained from a virus), called DNA ligase. The sticky ends join back together kind of like jigsaw puzzle pieces. The result: a cut-and-pasted mixture of human and bacterial DNA.
The last step is putting the new, recombinant DNA back into E. coli and letting the bacteria reproduce in a petri dish. Now, the scientist has a great tool: a version of E. coli that produces lots of human insulin that can be used for treating people with diabetes.
So, what is cloning? Strictly speaking, it's making many copies. However, the term is more commonly used to refer to making many copies of a gene, as in the E. coli example above. Researchers can also clone entire organisms, like Dolly the sheep, which contained the identical genetic material of another sheep.
Got It?
Besides the sequence of nucleotides in genes, what are some other changes to DNA and RNA that can affect our health and who we are?
Can you imagine treatments—other than vaccines and current medicines—crafted from genetic information and new molecular tools?
How is cloning a gene different from cloning an animal or a person? How do researchers use gene cloning to study health and disease?
Do you have any recurring illnesses in your extended family?


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Let LF Market Regional Properties To
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Our Sales Team
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text: You can play Boxhead Xmas free online shooting games at fogames. It has tags: Shooting,Christmas,. It has 1438 total plays and has been rated 91.7% (54 like and 7 dislike), find the fun and happy day. If you want to play more shooting games, we find some of the game: Effing Worms Xmas, Factory Balls Xmas, Boxhead More Rooms and Bloons 2 Xmas. To play other games, go to the shooting games page, the christmas games page, or just check out the new games or best games page.


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Jump to navigation Jump to search
|Look up commentator in Wiktionary, the free dictionary.
A commentator is a person who comments or expresses an opinion on a subject.
Specific commentators may include:
- A pundit, who offers to mass media their opinion or commentary on a particular subject area
- A political or social commentator, who practices advocacy journalism by adopting a non-objective viewpoint for some social or political purpose
- A biblical commentator, who offers comments on the Bible
- A sports commentator, who gives a running commentary of a sports game or event
- A color commentator, who specifically provides expert analysis and background information during a sports game or event in real time
Commentator or commentators may also refer to:
- those who wrote commentaries on Aristotle in the Middle Ages
- Postglossator or commentator, a member of a European legal school which arose in France in the fourteenth century
- Averroes (1126-1198), Muslim polymath and philosopher known as "The Commentator"
- Commentator (horse), American Thoroughbred racehorse
- "The Commentators", a 1985 UK hit single/parody by the impressionist Rory Bremner
| disambiguation page lists articles associated with the title Commentator.
If an internal link led you here, you may wish to change the link to point directly to the intended article.


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It's been a weird year for factory MotoGP bike debuts. With Ducati now a part of Audi AG, the Italian team's Wrooom! debut event was nixed, as it was jointly hosted with Ferrari.
Meanwhile in Indonesia, Yamaha Racing debuted in what looked like a basement service closet, though thankfully Movistar has come on-board as a title sponsor, creating the need to retake the team's livery photos — hopefully with a little post-processing this time.
Just two weeks away from the opening round of the MotoGP season, in Qatar, Ducati Corse has now officially debuted its racing machine, the 2014 Ducati Desmosedici GP14.


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M Line Holdings, Inc. Announces First Quarter Fiscal 2014 Results
Revenue Up 37% to $2.7 Million and Earnings Reflect $447,725 Improvement Year-Over-Year; Company on Track to Achieve Fiscal 2014 Profit Objective of $1.5 +M
Jan 13, 2014, 08:30 EST
TUSTIN, Calif., Jan. 13, 2014 /PRNewswire/ -- M Line Holdings, Inc. (OTCQB: MLHC) ("M Line"), a provider of products and services to the precision high tech segment of both the aerospace and medical industries as well as seller of high end pre-owned Japanese Computer Numerically Controlled ("CNC") Equipment, today announced its results for its first quarter Fiscal 2014 ended September 30, 2013.
(Logo: http://photos.prnewswire.com/prnh/20140113/LA44709LOGO)
In the first quarter of Fiscal 2014, the Company increased revenue by $746,604 or 37% to $2,727,194 from $1,980,590 in the first quarter of Fiscal 2013, and improved net income by $447,725, achieving a positive net income of $105,761 versus ($341,964) the same period in Fiscal 2013.
Bruce Barren, CEO of M Line, stated, "We are extremely pleased with our fiscal first quarter 2014 results. Since becoming CEO, we have added new customers and relationships, and in the last few months alone, we have seen impressive improvements in revenue and profitability. Given the state of our business today, we are confident of our ability to continue to execute successfully, and to ultimately achieve our forecasted results of $1,500,000 profit for Fiscal 2014."
He continued, "Now and moving forward, shareholder capital appreciation is of utmost importance. The focus of our turnaround continues to be on increasing shareholder value through definable results - net earnings – which improved significantly in the last quarter. It is our belief that this trend will continue in the second quarter and beyond. Our low valuation today represents a significant investment opportunity for those looking to achieve sound capital appreciation, and we will continue to communicate this opportunity to the investment community as more milestones are achieved."
Tony Anish, M Line's COO, stated, "Despite having worked with a shortage of working capital, we have been able to use our limited resources to benefit the growth and profitability of the Company as seen in our first quarter results. We are looking forward to an exciting 2014, benefitting from the strong outlook in the aerospace industry for the ensuing 10 year period."
About M Line Holdings, Inc.
M Line Holdings, Inc. (OTCQB: MLHC). M Line provides products and services to the precision high tech segment of both the aerospace and medical industries as well as selling high end pre-owned Japanese Computer Numerically Controlled ("CNC") Equipment. Key customers of our group include Panasonic Avionics, UTC Aerospace Systems, Beckman Coulter and BE Aerospace as well as our exciting new relationship with SIE (Structural Integrity Engineering). The Company is headquartered in Tustin, California. For more information see our website at http://www.mlineholdings.com/
Forward Looking Statements
This news release contains certain "forward- looking statements." Forward-looking statements are based on current expectations and assumptions and are inherently subject to risks and uncertainties, some of which cannot be predicted or quantified, and many of which are beyond the Company's control. The forward-looking statements are also identified through the use of words "believe," enable," "may," "will," "could," "intends," "estimate," "anticipate," "plan," "predict" "probable," "potential," "possible," "should," "continue," and other words of similar meaning. Actual results could differ materially from these forward-looking statements as a result of a number of risk factors detailed in the Company's periodic reports filed with the SEC. Given these risks and uncertainties, investors are cautioned not to place undue reliance on such forward-looking statements and no assurances can be given that such statements will be achieved.
For Further Information
Contact: Tony Anish
SOURCE M Line Holdings, Inc.


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Become Your Best You!
May 2, 2016
President and founder of Frame of Mind Coaching, Kim Ades, was recently interviewed
on the Becoming Your Best podcast with host Steve Shallenberger!
|Listen Here!
You will learn:
-Why many highly driven people get stuck and frustrated
-How to milk negative experiences for the valuable info their contain
-How seemingly bad situations can be turned into positive ones
-And much, much more!
"Before we can control our thinking, we have to become aware of it."
-Kim Ades on Becoming Your Best
If you like what you hear in this interview, we welcome you to take our assessment!
|Click Here to Assess Your Frame of Mind!


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What men want from women?
Nice clothes.
Nice body.
Good credit rating.
Good job.
Smells good.
Etc etc.
What a list!
I looked at Mrs Gutman to see which of the things she has. The only thing she has is that she smells good. But that's not very hard to find in a woman. Most women smell good.
Now if you ask me, Mr Gutman, what's most important, it isn't even on Halley Suitt's list.
A woman must be kind, sweet and nice to be with. Someone who cares for her man, nurtures him, gives him a little confidence and a little loving when he needs some support. Most important he needs to be listened to when he has something to say, and left alone when, as John Gray explains, he needs to go into his cave.
A man who is supported is a happy man. It isn't the size and shape of her butt that matters as much as the depth and accessibility of her heart, and her respect for the male need of privacy, and above all else, to be a trusted source of strength and protection.


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By Tim Bedley
In my 25th year of teaching I made a major change in my classroom. I asked my families to opt out of letter grades.
This past summer, I did a lot of reading on the effect of letter grades on students. I became convinced that letter grades did more harm than good to the average student. I was determined to make a big adjustment in my 4th/5th combo class. But how?
The first week of school I held I parent meeting. Most parents attended. I got on my soapbox and explained my thinking on letter grades. Unfortunately I didn't have a solution. I was very transparent with my parents and admitted my lack of a plan. Here's what I talked about at the meeting.
Why do I not like letter grades?
- Grades are subjective and arbitrary. What is an A? Who deserves A's? If I give my students a math test, do the students who earn 90-100% deserve A's? Why? What if the test is too hard or too easy? Should I grade on a curve? I teach GATE, so how would that work? Shouldn't GATE students have a higher GPA than non-GATE students? How much higher? Was the math test given at a time when students were truly prepared?
- Grades give parents a false sense of security or insecurity. My kid got an A! Wow! She is doing great! Well, not necessarily. If a child earns a C, is that failure? Should a parent worry or rejoice?
- Grades don't communicate any specifics. What does it mean to get a B in social studies? What information does that give to a parent about performance?
- Grades vary greatly from teacher to teacher. For years, students from my 5th grade class who earned B's and C's from me have reported getting straight A's when they hit middle school. Why? Am I too hard? Are the middle school teachers too easy? I truly don't know and I don't believe there is any way to know.
- Grades don't motivate most kids. This is a generalization and of course there are exceptions. I have found that most kids in elementary school are most motivated by "getting it done." They just want to know that the assignment is over. I have offered retakes on tests many times over the years (on the student's own time) and have never once had a student retake to improve a grade.
What hurdles did I have to overcome with the absence of letter grades?
- The district requires that I fill in a report card, with letter grades, on each student.
- Parents love grades, particularly those with kids who tend to get good ones.
- Families know nothing else. Letter grades are a part of our American school culture.
- Misunderstanding and shunning by fellow teachers. It's hard to rock the boat. (I do not expect my colleagues to follow my "no letter grades" plan.)
- Honor roll. What do I do with all of the kids in my class who are accustomed of standing up before their peers at the end of each trimester to be recognized as honor roll students?
So the parent meeting ending without a resolution.
I sought council from my brother, Scott. He helped me to figure out a great compromise. I would throw the decision back to the parents. I asked each family to decide if they wanted to stick with letter grades or use an alternative. The alternative was to give students and parents feedback in the form of assessments, rubrics, data, and narratives. BUT no letter grades written on any assignments. 22 of the 31 students in my class and their families decided to opt out of letter grades.
What about report cards and honor roll? I still fill in report cards on these kids, but I don't give a copy to the parents. It remains an internal document only. I award "honor roll" certificates to students to recognize them for relative areas of strength. For example, one student was recognized for excellence in math and leadership. The non-graded students stood in front of their peers along with the honor roll kids. I spoke individually with each of my teaching colleagues and explained what I was up to. I also told them I was NOT trying to get anyone else to follow suit. No one seemed to have a problem with the de-grading of my class.
The first trimester has concluded. Each of the 9 letter graded students received a standard report card. The other 22 received a one-page narrative written by me along with several other forms of specific feedback throughout the grading period.
How has this effected the kids and parents? The verdict is still out. I will be sharing my observations in a post later this year. I heard very little back from any of the kids or parents after the first "report cards" went out. The little I did hear was positive. The parents appreciated the narrative. An example of a narrative is shown below (formatting did not work on the blog.)
I am interested in your thoughts, supportive or constructive. Please leave a comment.
Girl Student
1st Trimester Critique by Mr. Bedley
Girl is a WONDERFUL young lady. She comes to school ready to learn every day.
- Reading Almost doubled her AR goal of 25 points. Reads books that are at a good level for her. Able to stay focused on books for a sustained period of time. Averaged 80% correct on the 3 story quizzes. Able to focus when reading with a friend.
- Writing Very active on class blog. Writing improves all the time. Listens to instruction and learns. Effective collaborator with peer writing critiques. Follows directions and writes more than required.
- Math Near the top of the class in math. Tries to get all answers right and understand every problem. Careful with math consensus. Stays on task until finishes math in class. Excellent scores on math tests.
- Hit the Road Jack Valuable team member. Works hard to accomplish tasks. Learning a lot.
- Behavior, manners Excellent behavior. Loves to help out in class. Follows class rules and procedures. Uses manners consistently. Does not complain.
- P.E. attitude/effort Tries to do her best at P.E. A good team player, good sport.
- Peer relationships Gets along really well with other students. Very mature.
- Responsibility Homework always completed on time. She's only missed one stamp all year. Hard worker.
- Tutoring Girl is one of our best tutors. She's very thorough and cares for her tutee. She's very skilled at following the lesson plans and uses good judgement. She encourages her tutee.
- Research skills Girl knows how to find information on her own and use it to present her findings in a clear manner.
- Leadership Girl is a positive role model in the classroom. I would like to see her gain a little more confidence to lead other students and take risks.
- Speaking skills, discussion, pair share Girl knows how to share talk time, speak out in front of the class with good volume and clarity, proper English.
- Collaboration Good team member. Stays on task. Listens to the ideas of other students.
- Direction following Great at following directions.
Overall, I am extremely pleased with Girl and her performance in all subject areas. She is a model student! If you wish to discuss Girl's progress in more depth, please email me and we can set up a conference appointment.


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Urdu At A Glance
The Urdu and Hindi languages have a unique relationship: they're "mutually intelligible." That means if you can understand Urdu, you can understand Hindi, too. They're like fraternal twins—they share a common grammar and vocabulary, and are considered to be separate forms of the same language: Hindustani. But like fraternal twins, they're not identical. They're written in separate scripts; both languages have different cultural influences; and Urdu, not Hindi, is the language often associated with the Muslim religion.
In 1947, a newly independent Pakistan declared Urdu as its national language to avoid giving preference to any native Pakistani language. But nearly all Pakistanis—90 percent—speak a native language other than Urdu and use Urdu as their second or third language. Outside of Pakistan, some of the largest communities of Urdu speakers live in the U.S., U.K., Saudi Arabia, and Bangladesh.
For English speakers, Urdu's biggest challenge is learning to read from right to left. But once you master that, communicating with other Urdu speakers is easy: the Urdu keyboard is available on Apple's Macs and mobile devices and Microsoft's laptops and PCs.
Want to meet new people—lots of new people? Learn Urdu, and you can converse with 500 million people throughout the world. Do you like watching movies? Bollywood, the world's biggest film industry, releases 1,000 movies each year—twice Hollywood's output—and almost all of them are in Urdu. And if you're an avid reader and Urdu speaker, consider jumping on a plane to India, where more than 3,000 Urdu publications, including 400+ newspapers, await. Knowledge of Urdu also puts you on the fast track if you want to learn Arabic, Farsi, or Kurdish.
The language of Urdu holds an esteemed place in literature and religion, too. Many revered religious texts are written in Urdu, including one of the world's largest collections of Islamic literature and translations of the Qur'an. The rich literary tradition of Urdu poetry, which originated in the 17th century, features several poetic genres and is treasured in the Urdu-speaking community as well as worldwide.
There are also practical reasons to study Urdu, especially if you aspire to become a linguist, translator, or teacher in South Asia. Looking for a job in the financial, intelligence, technology, public health, or film industry? Speaking Urdu can help you break in. If you want to know more about the Afghanistan or Pakistan regions, Urdu is a valuable tool. The State Department considers Urdu a "significant language," and offers undergraduate and graduate scholarships for its cultural immersion program. Learning Urdu opens doors to new discoveries, new relationships, and new opportunities, in places that were once home to some of the oldest civilizations on Earth.
What can you do with Urdu?