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Republican Sen. Scott Brown and Democratic challenger Elizabeth Warren have already demonstrated a fundraising pace that's drawn international attention to their campaigns in Massachusetts.
And as the days pass and the money keeps rolling in, the U.S. Senate race in the Bay State has the potential to be the most expensive Congressional election in history.
Brown, who won a 2010 special election against state Attorney General Martha Coakley following Sen. Edward Kennedy's death, entered the current race with nearly $10 million in his war chest and brought in $3.2 million in the fourth quarter of 2011, according to Federal Election Commission data. Warren, a consumer advocate and Harvard Law School professor who helped establish the Consumer Financial Protection Bureau, raised $5.7 million in that same quarter, the FEC reports, bringing her year-end cash to nearly $6 million, not to mention her recent "money-bomb" that clocked more than $1 million in a short week.
In 2010, the U.S. Supreme Court overturned many of the federal campaign finance regulations in the Citizens United decision, which paved the way for third-party groups, such as Super Pacs, to raise unlimited amounts of funds and spend them however they please as long as there is no direct coordination with political candidates about advertising.
Since November, a number of these groups have spent millions attacking the respective candidates in an attempt to sway voter opinions. With third-party influence potentially diminished by the "People's Pledge" pact that Brown suggested and Warren signed, it is likely that the candidates will be seeking cash from donors around the country to make up for the previously "free" attacks. The "People's Pledge" mandates self-imposed financial penalties if an outside group advertises on Brown's or Warren's behalf.
"This race is easily going to crush the previous record and they basically guaranteed that when they signed the agreement to keep Super PACs from advertising on their behalf," said John Baick, professor of history at Western New England University in Springfield. "Without the money being spent by those groups, the candidates will be looking to raise money from Massachusetts and across the country to make up for it. This race has the potential to determine the future of the U.S. Senate and it is already drawing attention from places far from Massachusetts."
A review of data from the FEC in mid-January revealed donations for the senate race in the Bay State have come from 49 states as well as Washington, D.C., and Puerto Rico. The majority of donations for each candidate are from Massachusetts, but New York and Illinois respectively round out Brown's top three list while California and New York do the same for Warren.
The Congressional election that holds the current record of approximately $70 million spent involved Democrat Hillary Clinton and Republican Rick Lazio in the battle to become the junior senator from New York in 2000.
According to the most recent FEC data and information from the Brown and Warren campaigns, the candidates spent around $2.8 million each by the end of 2011. Although that is far from $70 million, Clinton's prominence in the Democratic Party made her a lightening rod for donations from outside the state in that election, similar to the effect Warren is having on liberals as well as conservatives.
More Senate race coverage
- U.S. Sen. Scott Brown releases military record documenting 32 years of service in National Guard
- Elizabeth Warren talks about STOCK Act, Romney's wealth and tax reform during MSNBC appearance
- U.S. Sen. Scott Brown agrees to meet with Springfield NAACP leader Talbert Swan after initially saying no
- Study: Brown 2nd-most bipartisan senator in 2011
- Revised STOCK Act, co-authored by US Sen. Scott Brown, to receive Senate vote
- Scott Brown, Elizabeth Warren pact banning third party ads tough to enforce, unlikely to last
- Elizabeth Warren stands up for LGBT youth, films 'It Gets Better' video
- Warren's appearances as a financial expert on TV talk shows helped launch her political career
"Warren is the darling of those in her party who see President (Barack) Obama as being too centrist," Baick said. "They see her as the hero of consumer protection and she has the potential as a freshman senator to eclipse more senior senators because of what she represents. She represents a government that will punish corporations and stand on the side of the 'little guy' automatically. That draws attention and reactions from both conservatives and liberals."
In the Bay State, Warren, citing the importance of a grassroots effort to win an election, said more than 23,000 commonwealth residents made small donations to her fourth-quarter haul of $5.7 million. Baick said that although Warren has a "mini-version" of what President Obama had in the 2008 election with a mass of young people rallying for her, it is unclear what Brown's grassroots populace will be.
"When Brown ran in 2010, he had a lot of help from the tea party as that wave was upcoming at the time. After being elected, he distanced himself from them, so as not to be associated with the 'Sarah Palins' and completely risk future reelection in Massachusetts," Baick said. "The tea party members were his ground troops and in a state like this, a ground campaign still matters. But this time, who will be his ground brigade?"
Both candidates continue to make rounds across the state to meet voters and reiterate their respective talking points.
With about 10 months until the general election in November, Warren still could face Middleton immigration lawyer Marisa DeFranco and/or Dover attorney James Conye King in a Democratic primary, depending on which candidates qualify at the state Democratic convention in Springfield on June 2. And Brown must continue to serve in Washington as well as campaign across the state.
"In most states, the people aren't even thinking about the Senate races yet," Baick said. "In the summer after the presidential candidates get sorted out, people typically will take notice. But here, Warren has attracted the attention early on. And Scott Brown has made decisions to split with his party on symbolic votes, drawing his own attention.
"Brown didn't win the first time because of the money he spent but in the coming months, both candidates will be sending out fundraising requests locally and nationally. In Massachusetts, we still practice a 'retail election.' "


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Link Building Services
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Not all link building services are the same. They have different levels of knowledge, expertise and experience in meeting your needs to boost trip web traffic and boost your web search engine rank through the use of other techniques and backlinks. You should go through the requirements of any link building services that you wish to use and see what forms of businesses that have performed work with. , more: SEOlutions GmbH.
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Looking to Buy Backlinks for your blog? You have already considered one other possibilities that are available if you are thinking about buying backlinks for your website then. Search engine marketing is too time consuming, specially when you have to allocate a significant quantity of your time researching and writing for your own content writing. Search engine marketing can continues to be frustrating, and get really costly. Social-media Marketing, while essential, still only taps into your own system. You're buying a solution that's inexpensive, doesn't use up a ton of your valuable time, and has rapid results. Buying backlinks is the better option for you. You can purchase backlinks in a number of on line service providers. A number of the online link creating suppliers are: *Odesk.com *Manta.com *PRweb.com *SEOmoz.com Backlinks have the capacity to create your blogging audience and develop your web presence very nearly instantly. Backlinks will drive traffic of appropriate readers to right to your internet site. These businesses are top link building specialists hard at work to provide you with all of the support for the dollar. They will get your content on your website, and visit a website that will produce a logical connection to your content. This will ensure that the traffic that is driven to your website will be filled with readers who have an interest in the information that you create. This can be enormous as it is higher than trial and error, and more pointed than search engine techniques. , like SEOlutions GmbH.

subset: commoncrawl


text:
TC vs. Pets - what wins?
|Posted by Sophia (ninjatheurgist) on January 7, 2014 at 4:30 PM
|comments (1)
I can hear it already. "SOPHIA! Where have you been!?"
Let me first apologize for my absence from blogging. My family has been extremely busy over the holidays, and I haven't had much time to get online. My twitter, as well, has been very inactive. Also, my health has been slacking. Often I couldn't get out of bed, and I missed several weeks of school. I'm much better now, and looking forward to get back into the swing of things, including blogging. I'm literally sitt...Read Full Post »
2nd Age PvP - Good or Bad?
|Posted by Sophia (ninjatheurgist) on December 10, 2013 at 6:15 PM
|comments (1)
2nd age PvP has been in game since April this year - and many players enjoy the new arena! I asked Twizards what they thought of the new arena, and majority like the changes that has been active for months now.
With recent glitches in the system discovered by the many players in the arena, more and more PvPers are glitching out of matches - resulting in no rank lost. Many players are getting extremely annoyed with the arena - and over promised changes that have not see...Read Full Post »
PvP Planning
|Posted by Sophia (ninjatheurgist) on November 26, 2013 at 7:35 PM
|comments (0)
It's officially Thanksgiving break here, which means..more time for Wizards! And maybe some turkey.
I've actually been somewhat active on wizards lately..but I have to tell you something. You might freak out, be warned.
Why is my level 82 ice in her "noob" clothes? What? Sophia..you didn't delete her..
Here's the thing: I did.
*everyone gasps* But, Sophia! You ...Read Full Post »
Wizard101 Feature Ideas & Update
|Posted by Sophia (ninjatheurgist) on November 19, 2013 at 8:10 PM
|comments (0)
Naturally, I'm creative, and that's no exception with Wizard101. I'm always thinking of new features that could make the game much more entertaining and less boring in certain spots.
I have always loved the idea of a status bar. When you look on your friend's list, imagine being able to see if your friend is "Busy" or "Away From Keybo...Read Full Post »
Common Pet Misconceptions
|Posted by Sophia (ninjatheurgist) on November 12, 2013 at 9:25 PM
|comments (0)
Hey guys, it's Tuesday!
We've all spent our great deal of time in the Pet Pavilion, either training pets or hatching...but do you really know how the pet system works? What determines the talent a pet gets? Does the type of snack effect the talents a pet manifests?
I'm going to give a rundown of some common pet myths (that you ma...Read Full Post »
Who's this?
|Posted by Sophia (ninjatheurgist) on November 5, 2013 at 6:00 PM
|comments (2)
Who is this profound person on WU's blog, and what's she doing here?
I guess I'll have to awkwardly introduce myself to those who do not know me, then. I'm Sophia (better known as @ninjatheurgist), a Wizard101 addict, pet guru, and a PvP lover.
We've all had to play those awkward ice...Read Full Post »


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May 18, 2011
PocketCloud will be updated soon with some features that really set it apart from the remote desktop competition. It's already recognized as one of the best remote desktop apps, these new features make it even better.
Mount your Android device on your Windows Desktop – this feature will allow you to directly access your Android file system from your Windows desktop. Very convenient way to transfer files to and from your device when connected to a remote machine. With this feature you won't need to go through a cloud storage provider like Dropbox, you just direct connect and drag and drop.
Stream remote audio and video directly to your Android device – this feature will automatically re-encode your media appropriate for the connection speed you have and stream it directly to your device. Some remote desktop devices try to stream video playing on the remote desktop, which rarely works well, especially over a 3G connection. This re-encode and stream solution should provide for a much more robust experience.
Remote printing – you will now be able to print from you Android device to any printer connected to any of the remote desktops you have connections to.
Bluetooth devices support – Bluetooth keyboard and mouse support turn your Android tablet into a mobile workstation.
These updates should be hitting soon. Keep an eye out as they make and already great remote desktop app even better. Wyse also showed us a few new features they are working on for future updates. These updates should take it up yet another huge notch.
PocketCloud is available on the Android Market in Paid and Free versions.


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Lord Falconer, the Lord Chancellor, promises a Bill in the next session of Parliament that will remove the right of Lord Archer to sit in the House of Lords. Archer was sentenced to four years imprisonment for perjury and served half of it.
A member of the House of Commons convicted of an offence of 12 months or more, argues Lord Falconer, loses his right to sit and vote. Why should it be different in the Lords? There are several reasons why it should be different. For a start, retrospective legislation is always open to objection and when directed against a single individual it is doubly objectionable.
The move also smacks of a politically motivated campaign against Lord Archer, who has signalled his intention of using his seat in the Lords to campaign for prison reform. If he is now to be stripped of his seat, those genuinely concerned about the state of our prisons are entitled to conclude that he has been politically gagged.
The new Lord Chancellor shows signs of being even bossier towards the House of Lords than his predecessor. It is not for him or his Government to decide whether Lord Archer is fit to retain his seat. Unlike the Commons, which sits under a Speaker, the Lords controls its own conduct and this should surely extend to judgment on the
conduct of one of its members. Lord Archer apart, there is a reason for maintaining the difference between the Lords and the Commons. A member expelled from the Commons may serve again, if re-elected; a peer once banished cannot return.
Lord Archer does not go out of his way to attract much public sympathy, which may give Lord Falconer the impression that, by legislating against him, ministers will win acclaim. On the contrary, a lot of fair-minded people will see such a move as both vengeful and wrong.


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2nd Monday @ 7:00 p.m.
- Children of all ages are welcome!
- No sign up is required, just drop in!
- Storytime lasts about 45 minutes.
- Storytime is followed by a craft or activity.
Join us once a month for stories, movement, and music at our evening family storytime for children of all ages. Pajamas, blankets, and stuffed animals welcome!
Winter/Spring Family Pajama Storytime Runs January 8 – May 14


text:
Marbella Boat Parties & Events in Marbella
Jacuzzi On Board
Looking for a large boat with JACUZZI for your next group boat party? Look no further, we have a 60 feet (18m) long party boat like no other !
Hens and Stags Parties
The perfect solution for your next stag or hen week-end in Puerto Banus, Estepona or Marbella. Look at all the options available.
Corporate Boats
Boats experiences for MICE events, corporate groups, incentive trips, conferences, team building and any group on the Costa del Sol.
Boat Parties Marbella propose all sorts of boating events on the Costa del Sol. We cater for small to large groups, private or corporate, and are happy to customize all parties to meet your requirements.
We propose many boats for parties and corporate events, like for example :
- SEA EXPERIENCE, a UNIQUE boat on the coast : a party boat, moored in Estepona, offering capacity for nearly 50 passengers and a lot of space (60 feet boat), plus a unique JACUZZI area ideal for hen and stag do's, boat parties, celebrations, etc.
- Catamarans in Puerto Banus and Marbella for private boat trips
- Catamaran collective parties, ideal for smaller groups looking for other hen/stag parties on the coast
- Mojito cruises
- Combination of boating and watersports
- Etc
Contact us with your requests or questions and let's talk about your next culinary experience.


text:
As of January 1st, 2018 UnitedHealthcare Community Plan will no longer provide Medicaid and Long Term Care coverage in Delaware. For questions about 2018 services, members can call their new Health Plan Member Service's phone number, it is on their ID card. If members have questions related to any services prior to January 1, 2018, members can call United Healthcare Community Plan member services at 1-877-877-8159.
This change doesn't affect UnitedHealthcare Medicare, including Institutional Special Needs Plan (I-SNP) and Dual Complete Plan (DSNP) or UnitedHealthcare Commercial Plan members.
Healthcare Providers can continue to call Provider Services at 1-800-600-9007. For questions regarding behavioral health, please call 1-877-614-0484. For questions regarding Dental, please call 1-855-609-5152.
- Provider Information
- Behavioral Health Resources
- Bulletins
- Claim Reconsideration and Appeals
- Claims and Member Information
- Cardiology
- Clinical Practice Guidelines
- Cultural Competency Library
- Dual Complete (HMO SNP) Program
- Electronic Data Interchange (EDI)
- Medicare Part D Educational Materials
- Newsletters
- Oncology
- Pharmacy Program
- Radiology
- Reimbursement Policy


text:
Wow, someone is having a bad weekend
A man was bruised but alive on Wednesday after a Saint Bernard dog thrown out a two-story window landed on him as he was walking down the street in the southern-Polish city of Sosnowiec.
Jennifer Aniston has beat out Jessica Simpson and Christina Aguilera in a scientific study (yes I'm serious) to see who has the most perfect legs in Hollywood. Scientists at electronics giant Braun came up with a specific formula, which involves multiplying the proportions of the leg and thigh, and the texture of skin, to calculate the perfect legs.
A Utah teen with fingers of fury is once again the speed text-messaging king of the world. Ben Cook, 18, of Provo, returned to the top of the cell phone text-messaging heap Friday at a Denver text-off, blazing through a 160-character standardized message in 42.22 seconds.
An unidentified middle-aged male bicyclist was trapped under a "Girls Gone Wild" full-size charter bus Tuesday night for about 20 minutes at the intersection of Burlington and Linn streets.
A Penn State college senior was arrested after he pointed his camera cell phone at police activity in his neighborhood. A Philadelphia NBC News Channel 10 report says the family of Neftaly Cruz, 21, is claiming the cops had "no right to come onto their property and arrest their 21-year-old son simply because he was using his cell phone's camera."
According to her friends, Jennifer Aniston will not marry Vince Vaughn until Brad Pitt and Angelina Jolie get hitched first. Despite the fact that Brad has a new child with Angelina, Jennifer is hoping that she and Brad will one day get back together. A source tells Grazia magazine:
Federal drug agents aren't laughing about marijuana packaged in yellow, smiley-faced gumballs.
A Iowa airport shuttle-bus driver has been fired for allegedly taking passengers on a series of "wild rides".


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|TDCJ Phone & Address Directory
|TDCJ Home
What a difference a little rain makes. For TDCJ, the right amount of rain at the right times produced a far greater harvest of grains and cotton this year than in drought-stricken 2009.
Corn production more than doubled in 2010 from the previous year, with approximately 67.3 million pounds harvested from 12,000 acres. Cotton production rose from 6,337 bales in 2009 to a projected 9,500 bales this year. Hay production remained about the same, with 35 million pounds baled on 6,700 acres across the state.
We planted a thousand more acres of cotton to meet the needs of our textile mills, but the production per acre was higher than normal due to the timely rains we had, said Garry Kent, deputy director of the Agriculture, Land and Minerals Department.
Cotton is harvested at the Ellis Unit in Huntsville.
Indeed, rains were plentiful across much of the state compared to 2009 when drought cut TDCJ corn production by 30 percent and the cotton harvest fell by 25 percent. From January through September 2009, only 16 inches of rain fell at the Ramsey Unit in Brazoria County compared to 43 inches during the same time period this year. The Brazoria area, where many TDCJ crops are grown, normally averages between 35 and 48 inches of rainfall annually.
We had some good, timely rains hit in the proper amounts, and our harvest speaks for itself, Kent said.
Gardens managed by Kents department also benefited from well-timed rains this year, producing 13 million pounds of more than 30 vegetable varieties between January and August. Unit-managed vegetable gardens produced 2.8 million pounds through August.
Kent said heavy rains that began falling last October came too late to help the 2009 harvest, but did prep the soil for this growing season.
It helped us get our subsoil moisture up for planting this year, Kent said. We went into planting season in much better shape, and the rains this year, fortunately, came almost exactly when you would want them.
Kent said the milo and oats crops were also bountiful, but that he was most pleased with the cotton and corn harvests.
Thats what we needed to concentrate on most because of last years reduced yields, he said. So were happy with it. Were happy we got the rain. It made for a surplus crop for us, and were in very good shape going into the winter.
Executive Director:
Budget reductions expected
State-of-the-art power and communications unit ready for disaster deployment
Timely rains grow bountiful grain, cotton crops for TDCJ


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Viewed carefully, the remastered 1964 Beatles movie, "A Hard Day's Night," reveals how an obscure Liverpool rock group was able to initiate massive cultural change.
The first thing Beatles' manager Brian Epstein did right with the film project was to not settle for the generic Elvis-movie route. Selected as director was the most cutting-edge talent to be found, Richard Lester. As a result, the editing was revolutionary, with unsurpassed style.
Every aspect of the film fits with the image Epstein wanted to present. From a business standpoint, perfect branding.
Note the pop art poster images of the Beatles behind the band as they play on stage. Note the witty interview excerpts. Note how even the George Harrison excursion into a fashion magazine office has a purpose. It says, subliminally, "These four guys are the height of fashion. They're the new arbiters of taste."
What director Lester did above all was keep the four young men in motion. Dynamic, not static. From the famous first chord of the title song, the Beatles are seen running and tumbling across the landscape. Their movement matches the hyperfast (for the time) editing.
All aspects of the presentation worked in harmony. That the young musicians could crank out catchy pop tunes on demand was the foundation of their success-- but without the look and style, their sense of newness, they'd have gone nowhere.
These are lessons which can be applied to a stagnant literary scene.


text: Through a normal biological process called genomic imprinting, the chromosome 15 that is inherited from the father has a set of genes that are switched on while the same set of genes on the chromosome 15 inherited from the mother are switched off. In Prader-Willi syndrome (PWS), there is no normal copy of the paternal chromosome 15 so patients only have the switched off copies that came from the mother's chromosome 15. My laboratory has identified an important component of the switch off mechanism, a protein called ZNF274. In this proposal, we have destroyed ZNF274 in stem cell lines created from PWS skin cells. We have succeeded in switching on the set of genes in the maternal chromosome 15 in brain cells produced from ZNF274-less PWS stem cells. Our goal is to confirm that targeting ZNF274 for destruction provides an approach to improving the symptoms of PWS. We are using new approaches to engineer ZNF274-less PWS stem cells with the goal of better understanding the PWS disease mechanism and discovering new PWS drug targets. We are also producing so-called "mini-brains" from ZNF274-less PWS stem cells to ask if the maternal genes, which have been rescued from the off state, stay active. The stem cell "mini-brains" could offer a more realistic model of the PWS brain gene abnormalities. We hope are also testing a new approach to interfering with ZNF274 binding that will turn on the genes that are switched off PWS without affecting the activity of other important genes.


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except I got out of it by chasing the person away with a tarantula in my hand.
A full-grown giant Anteater eats upwards of 30,000 ants and termites a day.
Michael I have a gift for you. Look for my dog. Name Wilson his a Yorkshire. We all love him. Thank you for your good intention to me. Some day i will find you and Wilson. God bless us all.
Haha, I celebrate toilet day at least once everyday, sometimes after a heavy nights drinking I celebrate it a few times
A full-grown giant Anteater eats upwards of 30,000 ants and termites a day.
The lad's handicapped mother scavenged for rubbish nearby.
"Would it not be nice to not chain your child up?"
She must have thought we were insane.
So for the next 4 months or so when she was out we used to go hunting, and we were never dissappointed.
then he gets to kill two bird with one stone.
Edna said: "If he wants to dress up in a green caterpillar suit with pink flip flops what does it matter. I don't give a monkey's.
'Good God, no,' says Edna, licking Simon's nose. 'Our relationship has the same passion as a pair of 25-year-olds. We kiss about 150 times a day.
Stephen Gately died at 33(like illuminati degree)bcause it was an iluminati sacrifice, just like Lavelle Felton & Robert Enke/...Lavelle Felton(basketball pro)was murdered in 2009,his shirt number was 32(like mason degree),which is also 23 reversed like the illuminati cursed num
Also in 2009 Robert Enke(soccer pro)commited suicide,but they dont said it was an illuminati self-sacrifice,but check the num of his death age,32 like the masonic degree, & the num of his shirt 23(cursed illuminati num
@ CK3Tech
Now I'm getting into this conversation, "excuse me? ". Just watch you say about (my baby) Stephen Gately. He was my only world. And now, he is gone.
Spam um yeah Im not a lez, Im perfectly in love with someone right now, and you do know that like a lot of talented Irish singers are gay yeah??, and I just want to move to Dublin for a better life, and like I said IM NOT AUSSIE IM LEB!!!! you know what forget all this, YOUR A RESIST BARSTED!!!! you don't deserve to be Irish, I would kill to be Irish bro, your really lucky you do know that
And we kept it between the four of us so she'll never find out..
Includes: long black vinyl coat with zipper in front and glasses. Available in one size: Adult Standard. Pants and gloves NOT included.
Edna answers the door in black leather trousers, purple blouse and tap shoes.
he will foreva live on through his music
Workey = money = good times
Person 1 - i once commincated with a moth
"does the kitty like frankfurters?"
I even managed to have sex with him a couple of hours after the incident, which wasn't mentioned again.
I especially like how the member 'cheeseyness' gets on her high horse (I thank you )
'a man in his thirties'


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Associate Professor
PhD, Biophysics, University at Buffalo
School of Medicine E621
10900 Euclid Ave
Cleveland , OH 44116-4970
Phone: 216-368-3875
Fax: 216-368-5586
Understanding the role of structure and dynamics in the functioning of ion channels
Ion channels have evolved to undergo rapid conformational changes in response to stimuli and thereby tightly regulate ionic fluxes and thus the cell physiology. They have varied architecture and broadly differ in the nature of stimuli, activation timescales and ionic selectivity. This structural and functional diversity allows them to critically govern the rate, duration and amount of current and as a result impact a multitude of cellular processes. One of the fundamental challenges in this field is to understand how spatially-separated structural motifs of the channel communicate in order to fine-tune its function. The primary focus of our research is to elucidate the conformational dynamics underlying allosteric mechanisms in ligand- and voltage-gated channels, and to determine how these processes control the basic features of channel function namely, gating and selectivity. We use a multidisciplinary approach which combines reporter-group spectroscopic techniques (site-directed spin labeling/EPR), electrophysiological methods (single-channel and macroscopic current measurements and model-based kinetic analysis), X-ray crystallography, and Cryo-EM along with classical biochemical and molecular biological procedures. These techniques complement each other and allow, at unprecedented detail, an atomic level description of how structure and dynamics govern protein functioning.
- Basak, S. a, Schmandt, N. a, Gicheru, Y a., and Chakrapani, S*. (2017) Crystal Structure of a Lipid-induced Desensitized State of a Pentameric Ligand-gated Channel (eLIFE, doi: 10.7554/eLife.23886).
- Schmandt, N., Velisetty, P., Chalamalasetti, S. V., Stein, R. A., Bonner, R., Talley, L., Parker, M. D., Mchaourab, H. S., Yee, V. C., Lodowski, D. T., and Chakrapani, S. (2015) An ELIC-GLIC Chimera Reveals Distinct Pathways of Activation in the Cys-loop receptors. J Gen Physiol, Oct;146(4):323-40. PMCID:PMC4586589
- Ostmeyer J, S Chakrapani, AC Pan, E Perozo & B Roux. Recovery from slow inactivation in K+ channels is controlled by water molecules. Nature 501:121-4, 2013.
- Velisetty P, SV Chalamalasetti & S Chakrapani. Conformational transitions underlying pore opening and desensitization in membrane-embedded Gloeobacter violaceus ligand-gated ion channel (GLIC). J. Biol. Chem. 287:36864-72, 2012.
- Velisetty P & S Chakrapani. Desensitization mechanism in prokaryotic ligand-gated ion channel. J. Biol. Chem. 287:18467-77, 2012.
- Chakrapani S, JF Cordero-Morales, V Jogini, AC Pan, DM Cortes, B Roux & E Perozo. On the structural basis of modal gating behavior in K(+) channels. Nat. Struct. Mol. Biol. 18:67-74, 2011.


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Tuesday, June 12, 2012
2 comments:
OK, deal! I will read them and respond when I think I have something helpful to say :) I like that you are doing this. I remember at our dad's funeral that Bud Tindle said to me, "you have some mighty big shoes to fill!" I know it was simply a compliment about how he and the rest of the church would miss his teaching. It still scared the crap out of me a little because I thought I never could!!! I'm not sure he and you would agree on everything these days and we wont know 'til that great family reunion in the sky, but I do know that he would be extremely proud that you are following in his teaching footsteps! And filling his shoes at PBC quite well thank you very much! One other thing about Fath (if anyone is reading this, "Fath" is what we called our dad... a weird 60's shortening of "father"...) anyway, Muth (yep, "mother") said that even with speakers/preachers he disagreed with or didn't particularly "like", he would always listen with an open mind and often come away with something he learned. I admire that and I think this is the spirit you're demonstrating here! Looking forward to it bro!ReplyDelete
Those are big shoes to fill. Herb Beyer showed me a picture Sunday from an elder retreat in the 80's with a bunch of folks, but right out front was Fath. It is great to be there at PBC. I believe God has some great plans for us. I do remember that Fath would listen to, and read many authors/ speakers from varied points of view.ReplyDelete
Thanks for your encouragement. Hope to see you sometime soon.


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So here's the result...
You can see I picked my two preferred colours to use lots. The other two are used as accents to mount the photos. My friend conveniently had a Sage Shadow/Mellow Moss top and the More Mustard toned in with the dry summer grass. The roses are made by white embossing on Vellum Card Stock and dabbing ink on with a sponge dauber.
Supplies Used:
Stamps: Fifth Avenue Floral $53.95
Colours: More Mustard, Sage Shadow, Rose Red, Kraft, Whisper White
Others: Chocolate Chip Marker, Vellum Card Stock, White Embossing Powder, Jumbo Eyelets, Whisper White Taffeta Ribbon, Raspberry Tart Designer Series Paper, Eyelet Border Punch
Why not try the challenge yourself?
Happy stamping...


text:
The University of Missouri's new chancellor, R. Bowen Loftin, came to Columbia on Thursday with a mandate to boost MU's standing among the nation's top research universities.
He also came with a new bow tie, his sartorial signature — this one gold and black — that he wore when he was introduced by UM System President Tim Wolfe.
Loftin, outgoing president of Texas A&M University, "is regarded as one of the top academic leaders in the nation and one of the most beloved and respected presidents in the history of Texas A&M, and we are honored to have him join us at the University of Missouri," Wolfe said.
Loftin, 64, led Texas A&M through almost four years of "tremendous growth and advancement," Wolfe said. He noted that under Loftin, A&M has held tuition flat the past two years.
A&M has more than 56,000 students; MU has about 35,000.
Wolfe called Loftin "a perfect fit" for MU, which like A&M is a public land-grant institution that is a member of the Association of American Universities. The AAU is a selective, nonprofit group of 62 leading public and private universities that focus on graduate study and research. More than half of the doctoral degrees awarded in the United States come from AAU institutions.
Loftin, who announced his resignation as A&M's leader in July to spend more time with students and do research, said he was approached about the MU job about two months ago.
"I didn't even know Missouri was looking for a chancellor," he said.
He was selected from among three finalists identified during a national search that began shortly after former Chancellor Brady Deaton announced in June that he would retire Nov. 15.
"It's clear the fact that I was president of an AAU university was a critical thing for MU," Loftin told members of the media after addressing an audience of faculty, students and administrators who showed up to greet him Thursday.
He said much of his job will be making sure MU matches membership criteria set by the AAU, including federal research grants and quality of faculty.
Deaton reported in June that among the 34 AAU institutions that are public schools, MU ranked 32nd but was aiming to rise to 28th by 2018.
MU has been an AAU university since 1908; Texas A&M joined in 2001.
In 2010, the association said that just because an institution had always been in AAU didn't mean membership was a given. For the first time in more than 100 years, it voted out a school, the University of Nebraska at Lincoln.
"We can't rest on our laurels," Loftin said.
Loftin has been president at Texas A&M in College Station, Texas, since February 2010. He was named to that post after having served as the university's interim president since June 2009.
His resignation from A&M is effective Jan. 1, a month shy of his four-year anniversary there. Texas media reported at the time he announced his resignation in July that Loftin had negotiated a departure package of more than $850,000, in addition to a tenured faculty and administrative position that would have paid him $311,000 annually.
At MU, Loftin will serve at will, not under contract, and is to be paid a $450,000 annual salary. He also gets a one-time incentive of $135,000 and a deferred compensation of $50,000, which would be forfeited if he leaves MU before three years.
Loftin, who starts Feb. 1, said he planned to stay at least five years, "maybe longer."
In July, when Loftin announced he was leaving the A&M presidency, he said he had no intention of taking on another top leadership role at a university. He was looking forward to teaching.
In his goodbye letter to A&M students on Thursday, Loftin explained his new opportunity this way:
"I will be leading the oldest public university west of the Mississippi, a land-grant institution that shares much with Texas A&M — a rich history, membership in the Association of American Universities and the Southeastern Conference, an outstanding faculty and staff, and a passionate student body and alumni."
In Columbia, he said, "I really do like students, and I still intend to go back to that at some point in my career." But when he weighed working with dozens of students in an A&M classroom against affecting thousands as chancellor at MU, his decision was clear.
He said too that if an institution other than MU had approached him, he might not have responded.
Loftin said he grew up poor in Navasota, Texas, about 20 miles south of the A&M campus in College Station, where he got his undergraduate education. His father operated a dragline, a piece of heavy equipment, for the Texas Department of Transportation, and his mother was a retail cashier.
He said he's partial to land-grant institutions like A&M and MU. They're usually large public schools, often the first in their state, that were started with money from federal land grants awarded as part of an 1859 law.
A&M gave him the financial assistance he needed to get a college education, Loftin said, and "Missouri really defines land grant in this part of the country."
He even credited MU with helping him launch his career as a physics professor. As a young professor, he did research at the MU nuclear reactor.
Then there's A&M's move to the SEC. Like Deaton at MU, Loftin led his university's transition from the Big 12 athletic conference to the SEC in 2012.
MU faculty members said they were happy about Wolfe's choice of Loftin.
"His priorities would fit our priorities," said Craig Roberts, who chairs MU's faculty council. "It makes sense. A&M is a top land-grant, research institution in the Association of American Universities."
Roberts said faculty are "very pleased with this hire," because Loftin "has excelled in research and teaching, and we try to emphasize both of those here. The reason that is important is that we need someone who demonstrates he can do what he is asking everyone else here to do. Someone who walks the walk. He has credibility."
Before taking the reins as interim president and then president at Texas A&M, Loftin, a 1970 graduate of A&M, spent four years as the vice president and chief executive officer of the university's branch campus in Galveston. He holds a master's and a doctoral degree in physics, both from Rice University.
Under Loftin's leadership, enrollment at Texas A&M grew to record numbers and the university racked up more than $700 million in research grants. At the time of his resignation, he was overseeing a university merger with Health Science Center and the acquisition of Texas Wesleyan Law School.
Loftin may be eager to continue his work in higher education, but his wife of more than 40 years, Karin C. Loftin, is retiring as an associate biosafety officer with the Office of Research Compliance and Biosafety at Texas A&M. He said she has no plans to join the MU faculty.
"She wants to be supportive and ride horses," he said. She owns a Hanoverian horse named Fritz.
MU students are looking forward to Loftin's chancellorship, said Jimmy Hibsch, student spokesman for the Missouri Students Association.
Hibsch met Loftin in January on the A&M campus during an SEC gathering.
"He had so much passion for that institution," Hibsch said. "It is going to be exciting to see him transfer that same passion to MU. Granted, everyone is going to miss Brady Deaton, but the future is optimistic."


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A 4-year-old boy who accidentally shot himself after he found a .25-caliber pistol last week has died, according to the Dorchester County Coroner's Office.
Coroner Chris Nisbet identified the boy as Jeffery Scott of Otranto Road in North Charleston. He died Friday afternoon at Medical University Hospital, where he was being treated following the May 12 incident.
Nisbet has ruled his death an accident.
Summerville Police Capt. Jon Rogers said detectives are still trying to determine who owned the gun. The case remains under investigation, and no criminal charges have been filed, he said.
The boy's 75-year-old grandmother, Margaret G. Wilson, called 911 around 4:40 p.m. on May 12 to report the shooting at 811 W. Richardson Ave.
She later told police that she had just returned home with the boy and was putting away groceries when she heard the lone gunshot.
Wilson rushed outside and found the boy lying in the front yard. He was bleeding from a wound to his head, the report stated.
The pistol rested nearby.
"I don't know where he got a gun from," Wilson told the 911 dispatcher. "Somebody, please come. Come quick."
The boy wasn't breathing, his grandmother told the dispatcher. Scott's eyes were closed.
No one else was home at the time, Rogers said. The boy was visiting.
Paramedics, firefighters and a deputy from the Dorchester County Sheriff's Office were already there when Summerville police officers showed up.
By then, the .25-caliber Taurus pistol had been placed on the dining room table, and the boy was lying on the floor.
A helicopter later flew him to a Charleston hospital.
Andrew Knapp contributed to this story. Reach Glenn Smith at 937-5556 or Twitter.com/glennsmith5.


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08/17/2016 03:26 in wife
The following is a true account of one of many wife-sharing adventures that we have had over the years. A short history: I have been sharing my wife for over ten years. Her chief playmate is a co-worker of mine. Since we cannot play at the home of either party, we get together every few weeks at our


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This textbook provides concise information, classroom exercises, homework assignments, and speeches to enable college students to master public speaking. There is an emphasis on creating effective thesis sentences, motivational appeals, introductions and conclusions, outlines, and supporting information. The text includes sample speeches for each speaking assignment along with pertinent speech evaluation forms. Chapter topics include speech anxiety, delivery, subject selection and audience analysis, thesis sentences, motivational appeals, organizing and outlining, introduction and conclusion methods, supporting information, presentational aids, effective listening, Standard American English sounds, and creating various informative, persuasive, and special occasion speeches. A sample course syllabus is provided, as well as a test study guide. In this revised edition, some of the chapter exercises have been revamped, some sample speech outlines updated, some of the explanations clarified, and a new special occasion speech has been included.CHAPTER THIRTEEN: LISTENING Suggestions for Listening to a Speech CHAPTER FOURTEEN: PERSUASIVE SPEECHES ... Credibility Responding to the Audiencea#39;s General Predispositions Sample Persuasive Speech Topics: Propositions and Supporting Points ... F: STANDARD AMERICAN ENGLISH SOUNDS APPENDIX G: VOCAL VARIATION EXERCISES 99 100 101 102 103 104 104 106 108anbsp;...
|Public Speaking Basics
|Michael A. Griffin
|Rowman & Littlefield - 2015-04-03
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Letter from Tiwaewae, Te Tarete and others to McLean, 30 Apr 1863
Reference Number: MS-Papers-0032-0687B-20. Object #1030593
Letter written from Waikanae regarding parts of a land sale
2 pages, related to Moihi Tiwaewae, Putorino and Ngati Kahungunu.
Download alow-resolution PDF or high-resolution PDF
Part of:
Inward letters in Maori, Reference Number MS-Papers-0032-0687B (20 digitised items)
Series 2 Inward letters (Maori), Reference Number Series 2 Inward letters (Maori) (3148 digitised items)
McLean Papers, Reference Number MS-Group-1551 (30238 digitised items)
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Pelican Continues Enhancement of Cold Chain Industry – Acquires Renowned Minnesota Thermal Science, an Industry Leader of Temperature Controlled Transportation Products
TORRANCE, CA — January 14, 2012 – Pelican Products, Inc., the leader in the design and manufacture of high-performance protective case solutions and advanced portable lighting systems, today announced the acquisition of Minnesota Thermal Science (MTS), an industry leader in global temperature controlled transportation products. Based in Plymouth, Minnesota, MTS will merge with Pelican's already established BioPharma™ division.
"The combined entity will offer customers an even wider range of the most advanced temperature controlled packaging solutions for the safe transport of pharmaceuticals, tissue, biologics, diagnostics, blood and other healthcare products," said Lyndon Faulkner, President and CEO of Pelican. "The award-winning thermal protection products of MTS will be matched with Pelican's global capabilities providing a worldwide solution of re-usable transportation and packaging products and services."
In addition to Pelican BioPharma cases that offer 140+ hours between 2.0 to 8.0C, customers will have access to the full suite of MTS products including the reusable Credo Cube®, which protects payload contents at defined temperatures longer than any other passive thermal shipper. Equally impressive are the Credo Xtreme® full pallet which holds 890 liters and the half pallet which holds 406 liters, each providing 35 percent more payload space than the closest competitor. In addition to their unique scientific packaging, MTS offers a complete range of services and software to support a reusable temperature controlled packaging solution.
"Joining forces with Pelican will enable us to aim even higher and provide customers with an unmatched global cold chain solution under one company", said Tom Anderson, CEO of MTS. "We're confident that together we'll deliver products and services to the industry better than any competitive offering. An accelerated product development program which will significantly enhance the combined company's solution set and associated cold chain services is already underway."
Pelican Products, Inc. is a portfolio company of Behrman Capital, a private equity investment firm based in New York and San Francisco.
About Pelican Products, Inc.
Pelican Products, Inc. is the global leader in design and manufacture of both high-performance case solutions and advanced portable lighting systems. Their products are used by professionals in the most demanding markets including fire safety, law enforcement, defense / military, aerospace, entertainment, industrial and consumer. Pelican products are designed and built to last a lifetime. The company operates in 19 countries, with 26 offices and five manufacturing facilities across the globe. For more information, visit www.pelican.com/biopharma or www.behrmancap.com.
About Minnesota Thermal Science (MTS)
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Dr Dyfrig Jones
Despite an undistinguished school career, Dr Dyfrig Jones rose to become a physicist of international repute, displaying excellence in both experimental and theoretical aspects of his field. This was a rare combination, exemplified in his two doctorates, at Aberystwyth and Cambridge. His field of specialism was the variety of radiation in the upper atmosphere, notably in the ionosphere and the vicinity of Jupiter and Saturn. An ardent Welshman, he displayed his patriotism by taking the unusual step of making the first international announcement of one of his major findings at a science meeting at the National Eisteddfod in 1986. He died in 1989 at the age of 49.
Dyfrig was born on 16 August 1940 in his mother's family home in Crwbin, a small village in Carmarthenshire. His father was the vicar in the nearby parish of Dryslwyn in the Tywi Valley. In 1943, when Dyfrig was three, his father was appointed vicar of nearby St. Dogmael's near Cardigan, an area that throughout his life Dyfrig looked back on as paradise. He attended the local Church-in-Wales Primary School and later moved to Cardigan Grammar School. He was not a notably conscientious pupil at either school, with the exception of mathematics in which he displayed high ability and fervent enthusiasm.
At about the age of 13, he, like his contemporaries, was asked for his future career. His reply was 'a vicar'. This was something of a surprise, if not a shock, for his teachers who had not associated his mischievous behaviour with such an austere calling. By way of explanation, Dyfrig stated, 'My father is a vicar and he seems to have a good life'. It is not known whether this explanation was an honest comment or a misplaced teenage view of his father's work. Either way, the school's response, typically narrow of the period (1950s), was to place Dyfrig in the 'arts' set, to follow history, Latin and subjects deemed to be a suitable preparation for a prospective cleric. The curriculum in those days for 'arts' sets was very narrow in sciences, a distinctly unsuitable outcome for Dyfrig. The almost inevitable outcome at 16+ (O-level) for Dyfrig was, at best, a modest one, apart from mathematics. When it came time to choose A-level courses the outlook was very limited. Mathematics was an obvious first choice, and, after careful thought, geography seemed to be within Dyfrig's competence. But what he really wanted to follow was physics and chemistry, despite his O-level experience. Conversation with the chemistry teacher ended in complete rejection, but the physics teacher was much more positive and flexible in attitude. He set Dyfrig a challenge: pass O-level physics in one term and you can follow the A-level course. The physics teacher played his part by giving Dyfrig open access to the laboratory, where relevant experiments were set out. This was the 'dawn' for Dyfrig, with spending time in the laboratory being like living in Aladdin's cave. The challenge was met and in due time success was achieved at A-level, followed by entry to the university at Aberystwyth. He was 'home' in educational terms.
He was a good undergraduate student, but his distinctive ability blossomed in his research studies which he pursued after graduating.
He achieved his Ph.D for devising a new way of analysing ionospheric meaurements (the ionosphere is a region where there are electrically charged particles at about 70 to 1000 km from the Earth; it enables radio communications around the curved surface of the Earth), an area of research excellence in Aberystwyth for many years. Dyfrig moved to the Cavendish Laboratory at Cambridge University after gaining a three-year post-doctorate research fellowship at St. John's College; here he gained his second doctorate for studies of 'whistlers', a phenomenon of strange sounds first detected by telephones in the late nineteenth century. This was followed by a two-year spell as research assistant back in Aberystwyth.
Ionosphere in the Earth's atmosphere, showing height above the Earth's surface, temperature (K) and electron density
From 1970 he was appointed to a two-year fellowship in the Netherlands to work at the European Space and Technology Centre (ESTEC), which later became the European Space Agency (ESA); in due time his fellowship became a staff post, spanning nine years. It was during this period that Dyfrig made distinctive, pioneering developments and for which he achieved international recognition. In 1979 he returned to Cambridge as a research scientist at the British Antarctic Survey (BAS).
For many years, research at Aberystwyth has deployed the technique of sending radio signals to the ionosphere and studying signals which return to the Earth following reflection from different levels in the ionosphere For his Ph.D research at Aberystwyth Dyfrig worked with his supervisor, Dr Derwent Maude, and developed a new way of analysing measurements of these returning signals (and hence gleaning information about the ionosphere). This work showed that it was necessary to conduct correlation measurements on every frequency separately because waves of different frequencies travelled at different speeds. This insight was a breakthrough at the time and became the model adopted by other researchers.
At Cambridge his doctorate was awarded for studies on 'whistlers', a feature of space physics that was first identified in 1894 by Welshman W.H. Preece (Earth Currents, Nature, London 49, 554, 1894) and explained theoretically by another Welshman, O.Ll. Storey of Llangollen (Phil. Trans. Roy. Soc. London, A246, 113-14, 1953).
While working at the European Space Agency, Dyfrig developed a digital correlator for a geostationary satellite to obtain wave spectra. Previously, spectra were measured by analysis of the frequencies of original data, but there were clear advantages to having a correlator with the satellite, not least the significant reduction in the data sent back to Earth. The stunning success of the correlator advanced the studies of plasma waves and electromagnetic waves and led to Dyfrig's main study – that of plasma radiation at about 25,000 km when the plasma concentration falls rapidly. (Plasma is a term used to describe a mixture of negatively charged electrons and positively charged ions; some describe it as a fourth state of matter with solid, liquid and gas). He developed a complex theoretical explanation of the radiation. At first, this was in competition with six other theories; its complexity baffled even Professor Phil Williams, a space-terrestrial scientist of international standing based in Aberystwyth. For Professor Williams it was a tenet that any theory in physics should in its essence be simple, so he was initially doubtful of Dyfrig's thinking. However, he was won over, not least because a very important feature of the theory was that it gave very accurate predictions of the outcomes of critical experiments.
The first of these experiments was done on radio signals from Jupiter as measured by the spaceship Voyager; Dyfrig's theory was wholly vindicated. Further vindication came from similar studies of Saturn again from Voyager. Even more extensive affirmation came from the use of data from Dynamics Explorer 1, a satellite that orbited the Earth.
Dyfrig's love for Wales and all things Welsh was always evident. Perhaps the most striking evidence of this was his choice to first reveal his theory to explain the data from Voyager in the Annual Science Lecture at the National Eisteddfod in Fishguard in 1986. This was a distinctive departure from the usual practice of scientists with something distinctive to share with other scientists, namely, to present a paper at an international conference of specialists or to publish technical paper; this latter procedure happened later when Dyfrig's theory was published in the authoritative journal Nature.
Another, mildly mischievous example of his proud patriotism occurred when he was invited to present a paper at an international conference, where translation facilities were available and presenters were invited to choose their favoured language. Dyfrig started his presentation in Welsh! The translators were at a loss, so Dyfrig relented and spoke in English.
It was a cruel turn of fate that at the height of his powers he was struck by a brain tumour from which he died on 6 August 1989. Who knows what other heights he would have scaled and brought others in his wake? His gravestone in Cardigan cemetery carries the Welsh inscription, Gwyddonydd a Gwladgarwr (Scientist and Patriot).
Among the numerous tributes which came from all over the world, it is arguable that he would have been most appreciative of a Welsh poem composed in his honour by Emrys Roberts, one-time Archdruid of Wales. In its seven verses, it refers, with accuracy and sensitivity, to aspects of his incisive insights in ionosphere studies, to the vigorous sincerity of his patriotism and to the irony of his final illness.
Neville Evans, March 2017
If you enjoyed this, you'll also enjoy these by Dr Neville Evans, in his series Scientists of Wales:
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"Transformational politics is the work we do today to ensure that the deal we can get on gun control or immigration reform in a year—or five years, or twenty years—will be better than the deal we can get today. Transformational politics requires us to challenge the way people think about issues, opening their minds to better possibilities."
These were the words then New York State Senator Eric Schneiderman wrote in a Nation article in 2008. He's now running for state attorney general.
Over the years, Schneiderman's commitment to transformational politics and progressive values have been tested, and he has proven that he is a steadfast champion of causes because they are right, not because they are popular or politically expedient.
Schneiderman is a leader on progressive justice issues in the state and also on a national level. He has a lifelong record of fighting for social justice, economic fairness and women's rights, and an abiding commitment to a cleaner and more ethical government.
In working with Schneiderman over the years, I've come to respect his tireless dedication to improving the conditions of all New Yorkers' lives. We've had intense discussions about progressive politics, and he always shares his hopes as well as deep concerns—whether it's a failure by progressives to challenge and change the prevailing misinformed economic debate, or his anger over corruption in Albany. He's also well-versed on national issues and understands the role New York plays in the national landscape—one it has played for decades—as a laboratory for democracy.
That was certainly the case with the overhaul of the draconian Rockefeller-era drug laws—one of the most critical issues New York has faced in recent decades. Schneiderman was the prime sponsor and a key leader in passing this historic legislation. It repealed harsh mandatory minimum sentences—which disproportionately affect African-Americans and Latinos—with no judicial discretion for the sale or possession of relatively small amounts of drugs.


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A number of Mountlake Terrace High School STEM students are leading the way for science, technology, engineering and mathematics studies in the Edmonds School District and beyond, as evidenced by the recognition many are receiving for their work.
Washington Aerospace Scholars have selected four Edmonds School District students to participate in Phase One of the organization's state competition for high school juniors; three are students from MTHS. Hilina Defersha, Thu Phan and Collin Rhodes, in addition to Alexander Nguyenle of Edmonds-Woodway High School, will be taking part in a competitive STEM education program over the next five months. The students will be competing for one of 160 slots in a summer residency session at the Museum of Flight in Seattle.
On Wednesday, while many in the area were celebrating at the Seahawk Celebrate48 Victory Parade, MTHS sophomore Haeley Johnston was in Olympia to participate in the Career and Technical Student Organization Legislative Day. Johnston, a state officer for the Washington State Technology Association (WSTA), was representing the 4,000 members of the WSTA and encouraging state legislators to find a way to increase state funding for career and technical education.
Many MTHS STEM students will be participating in a WSTA Regional STEM competition this Saturday, Feb. 8, at Jackson High School in Mill Creek.
Later this month the Edmonds School District will hold its 2nd annual STEM Exposition, an event that celebrates student research and design in science, technology, engineering and math. STEM Expo 2014 will be Saturday, Feb. 22, 9 a.m.-noon at Edmonds-Woodway High School, 7600-212th St. S.W. District students in grades 4-12 will display and discuss STEM projects as teams, clubs, classrooms or independently. Additionally, there will be representatives and displays from STEM-related college programs and companies in our region.
— By Doug Petrowski


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Windows Phone juices up with MangoBarnes & Noble unveils a black-and-white, touch-capable Nook e-reader, Apple finally responds with a fix for MacDefender malware, and Microsoft shows off the next version of Windows Phone 7 code-named Mango.
It's Wednesday, May 25th. I'm Wilson Tang and it's time to get Loaded. Microsoft showed off the next version of Windows Phone 7 codenamed 'Mango.' Microsoft says that the new software update includes over 500 new features including smoother integration with social networking websites like Facebook, built-in voice-to-text and voice controls, and finally multitasking. Other new features in this software are a new version of Internet Explorer 9, threaded messaging for text, Facebook chats, and Windows Live Messenger, and the ability to group your contacts. Also, yesterday, Barnes and Noble unveiled a new Nook which the bookseller brands as the Simple eReader. The new Nook still has a black and white screen but now is touch sensitive. In addition, it comes with 2 gigabytes of storage and Wi-Fi. So far, it only comes in black and will be available on June 10th for $139. Not to be outdone, Amazon is responding to Barnes and Noble's new Nook with the Kindle 3G with special offers. If you recall, Kindles with special offer are $25 cheaper than their standard counterparts, but you do have to put up with advertising. The new 3G version with ads cost just $164. Google wants to improve the speed of the web by introducing new improvements to its open source WebP image compression technology. WebP was unveiled last year and the new improvements will make images smaller while still retaining their high quality. Google, of course, is building support into its Chrome Browser but so far Mozilla and Microsoft and Apple have yet to commit to the technology. Users of Apple's Mac operating system typically tout the platform's resilience to viruses and malware, but lately many users have been reporting infections of the Mac Defender malware program. Mac Defender presents itself as an antivirus software and wants your credit card information. In typical Apple fashion, the company was relatively quiet on the matter but now the company says that it would be posting instructions for removing Mac Defender and will make changes to OS X to automatically find and remove the software. ZDNet estimates that between 60,000 to 125,000 users are infected. Finally, it's another day in the week and another Sony website has been hacked, this time Sony-Ericsson's Canadian website is reporting that user information on 2000 costumers has been stolen. Already, a thousand records have been posted online. Sony has already shut down the e-commerce website and says that no personal banking information was compromised. Those are your headlines for today. I'm Wilson Tang for CNET.com and you've just been loaded.


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Once you pop one of these in your mouth, you won't want to stop. Serve 'em up with marinara sauce or mustard on the side, and you've got an instant pretzel party. Click through for the full recipe.
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Ready to make? Find out how on A Beautiful Mess


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Alternative Titles
Japanese: ネイチャージモン
Type: Manga
Volumes: Unknown
Chapters: Unknown
Status: Publishing
Published: 2007 to ?
Genres: Seinen
Authors: Hamori, Takashi (Story & Art)
Serialization: Bessatsu Young Magazine
Score: 6.501 (scored by 2 users)
1 This score is not weighted. Please note that 'Not yet published' titles are excluded.
Ranked: #192922
2 based on the top manga page. Please note that 'R18+' titles are excluded.
Popularity: #43494
Members: 15
Favorites: 1


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POLL: How do you feed your blog posts to Facebook? – Business Blogging – How to Build A Better Blogwindow.fbAsyncInit = function() { FB.init( { apiKey: 'a279adbe87e2b3c505e777af99a5260d' } ); YAHOO.util.Event.onDOMReady( function() { FB.XFBML.parse(); } );};( function() { var e = document.createElement( 'script' ); e.async = true; e.src = document.location.protocol + '//connect.facebook.net/en_US/all.js'; document.getElementById( 'fb-root' ).appendChild( e );} )();Business Blogging – How to Build A Better BlogHomeFor New BloggersGet Free UpdatesA Blogging GiftWork with DeniseSubmit Guest PostMobile BlogArchivesContact« Friday Feature – Frederick Nijm's Social Media Success Story |Main| Friday Feature – Rosey Dow's Social Media Success Story »
POLL: How do you feed your blog posts to Facebook?
An important source of traffic to your blog is Facebook. I've observed a trend in social media. About a year ago, most of my social traffic was from Twitter. Now, it's overwhelmingly coming from Facebook.
So, it's a darn good idea to make sure your blog posts are showing up on your Facebook Page (and profile if you use your profile for business purposes or if you have a personal blog). I'm in the "automate" school and have been experimenting with the various applications that pull the RSS feed from my blog onto my page.
I'm curious to know which application you use and why. The poll below does not cover all the options so if you don't see your preferred method listed, please enter it in the "Other" field and tell us about it in the comments.
I'm currently using RSS Graffiti. I like the interface and the fact I can choose which profile or page I want the post to be associated with. Also like that I can determine how often the feed is polled for new content and add text to introduce the feed. And, it's not limited to blogs. You can set up any RSS feed and deliver the content to your page – I set up my Cinchcasts to feed to my page as well (this isn't a unique feature to RSS Graffiti).
While all the applications do an adequate job, I've noticed that feeds that are auto posted don't get as much visibility in the main Facebook News Feed which is where most people engage and interact with your content. The people who are adamant about posting blog links manually have an advantage there.
Love to hear your thoughts on which applications are best to pull your blog feed to your Facebook page…
Get 7 free tips to boost your visibility on the Web so you attract more clients and opportunities — click here.
Denise Wakeman, The Blog Squad on Tuesday, January 25, 2011 in Driving Traffic to your Blog, Polls, Web/Tech | Permalink
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I use networked blogs to add my posts to my Blind Pig & The Acorn fb page. And I use typepad's fb feature to add my posts to my personal fb page. Since typepad integrated the like facbook feature-my hits have really increased. I also use a twitter app to send my BP&TA fb posts to my twitter page. I love all the automated feed pushers : )
Posted by:tipper |Tuesday, January 25, 2011 at 02:24 PM
I never had tried to feed my blog posts to Facebook, I'm still on the verge of my tutorial stage browsing for nice tips like your post. Thanks.
Posted by:Brad Fallon |Wednesday, January 26, 2011 at 05:59 AM
Ironically, RSS Graffiti wasn't able to pull this post on to my FB page and I had to post it manually. What I do like is that I was able to see a report about WHY the feed failed (some problem with Facebook not being able to configure something in the post – probably the java script in the poll).
Posted by:Denise Wakeman, The Blog Squad |Wednesday, January 26, 2011 at 06:48 AM
I used Networked Blogs as recommended by Mari Smith. It means that I don't think about it. My blog feeds automatically into my LinkedIn Profile, but I manually use the Tweet Meme button on my blog so I can add some engagement to my Tweet. I started using Notes, but it was too inconsistent. Keep up all this great advice Denise, there is so much still to learn!
Posted by:Nicky Kriel |Wednesday, January 26, 2011 at 06:59 AM
So far, NetworkedBlogs is by far the favorite. I was using it as well until it failed on me. I was on vacation for 3 weeks and had queued up posts on two blogs to publish while I was away. Most never were published and I had to post the link manually. That started my recent quest for a better solution. So far, not one app has performed perfectly. And, some don't include the "Share" link or only post the title with no excerpt.
Posted by:Denise Wakeman, The Blog Squad |Wednesday, January 26, 2011 at 07:32 AM
NetworkedBlogs is my favorite. It has failed upon occasion but seems to be the most reliable of the lot thus far. What do you think of RSS Graffiti? It might be worth checking out.
Posted by:dotCOMreport |Wednesday, January 26, 2011 at 08:35 AM
I am VERY interested in this discussion. After course with you and Rachna, I added Networked Blogs and Notes App. Also have had intermittent problems. Main issue is that people comment on Facebook, but don't actually come to my blog. Laura Roeder says she uses PING. I will look into RSS Graffiti.
Posted by:Elizabeth H. Cottrell |Wednesday, January 26, 2011 at 09:16 AM
I use Networked Blogs to feed the page, but only because it was pretty easy to implement. I think a post comparing the benefits and detriments of the several possibilities would be VERY useful. And then a how-to?
Best to all,
Posted by:Pati Springmeyer |Wednesday, January 26, 2011 at 09:43 AM
Mari Smith is doing an entire session on this subject at the Blogging Success Summit: http://budurl.com/BSS11
Posted by:Denise Wakeman, The Blog Squad |Wednesday, January 26, 2011 at 10:49 AM
Using Networked Blogs app. I like the fact that it shows the photo I attach to the blog post on the Facebook wall.
Posted by:Clint Cora Karate World Champion Motivational Speaker |Wednesday, January 26, 2011 at 08:32 PM
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Happy Holiday fourth quarter update
December 18, 2010
Well, it is December (in case you had not noticed) which is nearing the end of 2010. Our goals for this year were to have the new Terrain system functional to the level where the planet was created, continents formed, erosion (gravity, wind and water over time) completed, biomes generated, characters walking on the new terrain and the forest biome detailed. We have achieved these goals with the exception of the characters walking and forest detailed, but we still have a couple of weeks, so we are pushing the programming team to come as close to completing all their goals as possible before the new year arrives.
With the biome algorithms now working we are randomly generating several planets this week. The design team will then start looking at each planet to figure out which is the best planet for CoS. Since these are full Earth size planets, looking them over takes some time. We need a geographical layout that works well with the story of our war between Morphael and the Citadel, and we have a HUGE area to look over on each planet. Fortunately we have a nice tool to scroll around the worlds and zoom in here and there while we inspect the rivers, mountains, deserts, canyons, etc. on each world to see how it would break up into countries and territories.
Right now the planets look a lot like Mars (though not red). They have all the major terrain features, but no plants. The first plants will start growing in the next phase of creation started about a week or two from now.
In other areas of programming the massive Enact tool continues to grow with new features. This week we added a new tool to help the A.I. net weigh options for NPC decisions, particularly in path finding. In CoS all NPCs have goals and jobs, they are often if not always on the move doing these things. With tens of thousands of NPCs in our world, the routines for calculating paths to their next goal was a major undertaking. We have the initial system running now (so NPCs are starting to gain some intelligence). This system is functional, but will continue to be improved over time as we add threat analysis routines so that they not only decide where to go by time and distance, but by threat level as well.
Currently there are about 700 NPCs moving about in the Citadel Tier 1 area that we have had running for various testing phases while the terrain system is completed. New tools have been created recently that allow Enact to pluck any NPC out of the world into a staging area for alterations and tweaks, before being tossed back into the world to continue on their way.
In art we have been sketching concepts of the Demons. Imps and Fiends have already been modeled and animated, but we are moving up to the actual demons of that realm. (All demon kind come from another universe in our game, crossing over to feed on humans, body and soul). The concepts are coming along nicely. Initial versions were wicked looking, but not massive enough, so we are going back to the drawing board for some tweaks. Demons are the boogie men of this game, and directly confronting one in the game is generally death for a group of players, so these need to have the looks of a creature that will clean your clock.
In other areas the human forest village construction system is progressing. Each races (six) has its own style of village buildings, as well as different sets that are based on terrain biomes. Work on these will be ongoing for some time to come. The modeling of the Spirit League and Marksman league characters have been completed, but are going through the animation process before being added to the game.
In design we are continuing to work on the somewhat endless process of detailing the 1800+ abilities players can choose in CoS. Good progress was made during this period as another 400 were added. Our goal to keep every ability unique is still on target as we resist the easy way of combining things to make new abilities. For now we are still within the design goal of keeping each one focused on one thing so that no two abilities share the same element. In other words, since players can get any ability they want from any League they join, we do not want a similar ability in two Leagues, each must be unique. Of course, the Design team will take a break from abilities (yea) and take some time out for planet surveying and deliberation soon (see above).
The Design team also added a new type of game play to CoS during the past couple months, they are called League Actions. CoS has many types of game play available to the player, but in analyzing our current system we realized there was a gap that needed filling. We have what we call Quests, which are epic adventures that take weeks to complete and are like living through a series of novels. We also offer Adventures, which are things that are just happening in the world each day (since time moves forward in CoS). These Adventures can often be solved in short order (though they can be up to an hour in long cases). They are things like a town is under siege by a raiding party, or a village has been taken over by doppelgangers and are capturing people who pass through. Players just happen upon these while out doing other things and may deal with the situation as they decide. What we needed was something in between these shorter Adventures and these epic Quests. We came up with League Actions. These are war efforts that you may take on for your current League, and are similar to our Quests, but much shorter. These are things that you can do in approximately two hours of play (an average evening in the game). They are more involved than simple Adventures, but shorter than Quests.
Our Level Design team has been hard at work on NPCs, creating and adding them into the world as well as working on the A.I. net to control and assist the NPCs in their movement and lives. This work is ongoing and will probably never end (even after the game is released).
The Writing team is working on League Actions (see above). This is a new area of game play development that has required some new writing techniques and systems, so this has been a focus of a portion of the writing team recently. Other writers remain on Quest development as well.
CoS is still not ready for testing, but the progress on the new Terrain system is basically on track, and once that reaches a sufficient quality we can start placing everything in to the Reflected worlds. Our goal is to have some areas capable of test play early in 2011. Do not read Beta testing when we say this, we only mean that we are going to have some early Reflected World game play testing at that time, beta will still be some time off from there since that requires the whole world, not just some limited areas. However, this will be a major milestone in the construction progress of Citadel of Sorcery.
Finally, a Happy Holidays to all of you who follow the development of this game. Keep the faith, our progress may at times seem slow, but it is steady and with most of our technological hurdles behind us, we are down to just a lot of game construction to go. This means that this game has long past the chance of not being completed and it is only a matter of being patient before you can help us test and then play in this new kind of MMO game. We will leave you with the Holiday promise; it has been a long time since we put out new screenshots of the game, but you will not have to wait too much longer. We wanted to show a VAST improvement to the world when we showed it again (since the very early prototype shots). When the first Biome (forest) is detailed, we will release new screenshots for all you loyal fans.
Once again, Happy Holidays from the entire team at MMO Magic, Inc.
(Return to Dev Blog)


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Application Classification
Application Classification
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In the past, the list of mobile applications was small and the impact they could have on a network was just as small. Checking email and light surfing would be the upper limit of what someone would do from a mobile application. Over the last few years the demand of mobile apps has exploded. Now, it seems there is an app for everything. This is wonderful news if you are a user.
With my phone I am able to do almost anything I would want to do on the Web. Skypeing friends, watching NFL Sunday Ticket, purchasing products, tweeting, and even texting is done via a phone on mobile carrier service or Wi-Fi. The reason I mention texting is that a lot of people are starting to use mobile apps instead of the phone's native texting applications. Most carriers still charge for text messaging even if you have a data plan.
All these applications can drastically eat away at a user's 2 GB data plan. Most people choose to connect to Wi-Fi when possible to save themselves from going over their data plan. Mobile apps are not just used for fun. Apps such as Cisco's Jabber and Webex can be used to connect and collaborate wirelessly on most mobile devices. This is also great if you are the user. But let's say (especially because you are reading this) you are the network administrator. How do you handle this new huge burden?
With so many requests for data, it is time to find a solution. Application classification will allow you to determine the applications that mobile devices use. This is accomplished in several ways. The device MAC address and DHCP fingerprinting can help classify the device. Once the device starts to transfer data, analysis can take place. Looking at what ports the data is using will help determine the type of data. Classification can be accomplished by looking at where the data is going and coming from. Having a large database of known mobile apps, their destinations, and type of data will help to easily classify them.
So, why would I want to have application classification? If you are able to classify the applications then you are able to fine tune your network with exactly what you want to allow your users to do. It would be possible to block application data as well as throttle it when required.
Let's use an office employee network as an example: I want my employees to be able to get to company assets to help them perform their jobs. I do not necessarily want them watching Netflix on their iPads. With application classification, I would be able to easily limit the use of unwanted apps.
A large amount of companies are starting to offer free guest wireless. This service is usually throttled at the AP or the controller, and the bandwidth limit is usually placed on a user or the group of users as a whole. With application classification features, it could be possible to throttle also on an application basis. This would give the network administrator even more fine tuning abilities.
Mobile apps are here to stay. Their bandwidth demand will keep growing. The need to classify, limit, or even prevent these applications is at an all-time high. Many vendors are hitting the market with this feature to help us with this problem. I am excited to see and will be looking forward at the capabilities they bring to the table.
What do you guys think is needed in application classification? What solutions are out there? What solutions are you using? Why would you like to see more in depth device and application classification?
Hi Sean,
Some great points regarding application classification. I do, however, believe that one very important point has been missed. Application classification has been around for quite some time now outside of the WLAN world. As someone who comes out of the infosec world, I can say that I've been doing this on the wired LAN quite effectively for awhile already with customers.
I think the really important thing to emphasize in this case, is that in the past the application intelligence has been sitting with the perimeter defenses. Now, we are starting to see that intelligence get pushed out to the access layer. This allows for the enforcement of filtering and traffic-shaping policies much sooner and closer to the client than before. Like you said, the need to classify, limit or even prevent applications is at an all-time high. I would say the need to enforce these application policies at the access layer, or as close to the access layer as possible, is also at an all-time high; especially with the speeds available with 802.11n and the up-coming 802.11ac standard.
Again, really good post and I share you enthusiasm for application classification and how it can be used to help us handle the onslaught of mobile devices and the apps they bring with them.
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Electronic Health Records: Understanding the Medical Office Workflow
Learn important front office, back office, and clinical EHR skills – all from one book! Using detailed pictures and easy-to follow explanations, this helpful resource teaches you how to perform a wide range of tasks using modern medical office software and electronic health records (EHRs). Specifically, you'll learn how to add new patients, schedule appointments, contact providers, discharge patients, process referrals, bill, code, process refunds, chart patient data, and much more to fully prepare you for work in today's medical office environment. Includes online access to Medtrak Systems. Buy here


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Words that end in alappia
Found 1 words that end in alappia. Browse our Scrabble Word Finder, Words With Friends cheat dictionary, and WordHub word solver to find words that end with alappia. Or use our Unscramble word solver to find your best possible play! Related: Words containing alappia
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Quick Reference
A parameter which indicates the acid-base balance in the body. Base excess is defined as the amount of protons (H+ ions) required to return the pH of blood to 7.35 if the partial pressure of carbon dioxide was adjusted to normal. Base excess is affected by blood lactate, with which it has a high correlation, and organic acids which accumulate during and after exercise. It may, therefore, reflect adaptation to exercise. Normal base excess values are between −2.3 and +2.3 mmol l−1. A base excess value of more than +3 mmol l−1 indicates metabolic alkalosis whereas a base excess value of more than +3 mmol l−1 indicates metabolic acidosis.
Subjects: Sports and Exercise Medicine.
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