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— "It is corrupt to use the tax laws as a cover for corporate lobbying, but it's even worse in this case. Exxon uses ALEC's charitable status to fuel its disinformation campaign on climate change, so taxpayers are literally paying Exxon to lie to them."
Constantine Cannon partner Eric Havian commenting on IRS whistleblowers' complaint alleging Exxon and a purported charity have colluded to finance a campaign denying climate change while violating the tax laws.
* * *If you would like more information or would like to speak to a member of Constantine Cannon's whistleblower lawyer team, please click here.

subset: commoncrawl


text: DOVER (June 25, 2012) -- The Delaware House of Representatives approved the autism insurance reform bill, SB.22, by unanimous vote. The measure, which would require health plans to cover autism therapies, such as Applied Behavior Analysis up to the age of 21, heads to Governor Jack Markell. Delaware would become the 32nd state to enact autism reform legislation.


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YWO > Community Forum > Need help writing a song for a pub scene in my fantasy book
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|View Post #1 (Link) Need help writing a song for a pub scene in my fantasy book
Literary Newbie
Join Date: Apr 2017
Posts: 2
Points: 5
Times Thanked: 0
What I have so far is something, but I am not proud of it. In my book, there's this guy that gets drunk and ends up doing a little foot stomping and singing on a table in a tavern. Can you guys help with the song? Here it is,
"Dance and sing at the jolly old pub
We are the bubs at this pub
have a mug of ale
If you want to run from life just take a sip to bail
I'll up and burst your gritty mug
Beer is a joy, Oh boy
The joy of the Day
Ale is the male off scale
Beer and song is the height of the night all along
When you sing a swing
At yer shady pub"
This isn't going to be all the song. I hope to add more if I can figure out a good topic and rhythm with rhyming. The song in a way is like an Irish jig. It needs to be a song that makes the reader want to dance. And the singer, by the way, has a pretty low voice.
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Join Date: Jan 2008
Location: ὡς ἐν ἄλλῳ κόσμῳ
Posts: 1,375
Points: 30
Times Thanked: 115
You do not post work here or in the Newbie Section. You post work in the writing forums which you can find by clicking the tab at the top called 'Writing'.
Please read the Site Rules, the Critique Guidelines, and the How to Critique Guide as these will help you understand how the site works and how to critique properly. If you have any further questions or worries, please don't hesitate to message me back.
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The Fess mss. consist of nineteen black and white undated photographs of paintings by artist Theodore Clement Steele, 1847-1926, and one of his studio in Brown County, Indiana. The photographs were made by Frank Michael Hohenberger, 1876-1963, also of Brown County, Indiana.
The photographs, titled in pencil in Hohenberger's hand, are: Belmont, The Cloud, Distant Hills, Early Spring, Early Spring - Hunnicutt Valley, The First Snow, Forest Interior, The House of the Singing Winds (on verso in unidentified hand - House of Mr. & Mrs. T.C. Steele), In Hunnicutt Valley - Late Afternoon, The Iris Drive, Morning Mists, The Peafowl (on verso in unidentified hand - Mrs. Steele In Their Living Room), A Serene Afternoon, Still Life, Turn of the Road, The Wheat Field, Winter Morning (on verso in unidentified hand - Copy of T.C. Steele Painting now owned by Indiana University), two untitled pieces: one a country scene, the other of two ladies, one seated, one standing (on verso in unidentified hand - Mrs. Steele Entertaining Herself), and Corner of the Studio.
In his diary, present in the Hohenberger mss. in Lilly Library, Frank M. Hohenberger noted on June 5, 1919 (p. 90 and 98) that he photographed the living room, the studio, and the painting of Mrs. Steele with peafowl. On Sept. 12, 1921 (p.208), he "made exposures of paintings at Mr. Steele's Studio." On Oct. 9, 1923 (p.281), "Mrs. Steele wanted me to copy some of the old oils in Munich."
Glass plates of some of the photographs are present in the Hohenberger mss. [See Vertical File for list]
Collection size: 20 items


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Fatigue Syndrome Day is celebrated on May 12th of each year. The staff at National Whatever Day were unable to discover the origin of Fatigue Syndrome Day.
Chronic fatigue syndrome (CFS) is the common name for a group of significantly debilitating medical conditions characterized by persistent fatigue and other specific symptoms that lasts for a minimum of six months in adults (and 3 months in children or adolescents). The fatigue is not due to exertion, not significantly relieved by rest, and is not caused by other medical conditions. CFS may also be referred to as myalgic encephalomyelitis (ME), post-viral fatigue syndrome (PVFS), chronic fatigue immune dysfunction syndrome (CFIDS), or by several other terms. Biological, genetic, infectious and psychological mechanisms have been proposed, but the etiology of CFS is not understood and it may have multiple causes. There is no laboratory test or biomarker diagnostic of CFS.
Symptoms of CFS include malaise after exertion; unrefreshing sleep, widespread muscle and joint pain, sore throat, headaches of a type not previously experienced, cognitive difficulties, chronic and severe mental and physical exhaustion, and other characteristic symptoms in a previously healthy and active person. Additional symptoms may be reported, including muscle weakness, increased sensitivity to light, sounds and smells, orthostatic intolerance, digestive disturbances, depression, painful and often slightly swollen lymph nodes, cardiac and respiratory problems. It is unclear if these symptoms represent co-morbid conditions or are produced by an underlying etiology of CFS. CFS symptoms vary in number, type, and severity from person to person.
Although fatigue is a common symptom in many illnesses, CFS is comparatively rare. Estimates of prevalence vary from 7 to 3,000 cases of CFS for every 100,000 adults; national health organizations have estimated more than one million Americans and approximately a quarter of a million people in the UK have CFS. CFS occurs more often in women than men, and is less prevalent among children and adolescents. Quality of life is extremely compromised.
Although there is agreement that CFS poses genuine threats to health, happiness and productivity, various physicians' groups, researchers and patient advocates promote differing nomenclatures, diagnostic criteria, etiologic hypotheses and treatments, resulting in controversy about many aspects of the disorder. The name "chronic fatigue syndrome" is controversial; many patients and advocacy groups, as well as some experts, believe the name trivializes the medical condition and they promote a name change.


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HunieCam Studio Free Download PC Game Cracked in Direct Link and Torrent. HunieCam Studio is a business tycoon / management sim game.
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Web 1 and Web 2 (Period 4) exams must be complete by Wednesday.
Checklist for exam:
1. Web 2 and Web 1: Do you have a link to a blog on your subject?
2. Citations are formatted properly.
3. Alt text, titled pages, etc...
4. Saved in Udrive correctly, checked all files.
When Done:
1. Save folder in udrive: bschneiderdogs-DONE. When it is marked Done I know to grade it.
2. Complete and score evaluation and submit on blog.
3. Move on in tutorials or book.
One note:
For Dreamweaver movies vs. Windows Movie Maker. Go to Flash. Import the movie you made in Movie Maker. When you save the movie in Flash you can then embed that Flash movie in Dreamweaver.
Web 4: This is the final day for Thinkquest. Triple-check your work on the thinkquest site. Please do the evaluation when you are done.
Monday, March 31, 2008
New Week
Web 1 and Web 2 (Period 4) exams must be complete by Wednesday.
Posted by Mr. Schneider at 6:31 AM 0 comments
Tuesday, March 25, 2008
OK, its Tuesday and still no baby. Its got to happen soon...
Web 4: Try to get final drafts of your diversity and collaboration pieces in my hands today. I will post your sites to thinkquest on Monday whether I am in school or not. Be certain that you have checked all your sources. Triple check that the site works on thinkquest.
Web 2 and Web 1: We will briefly review noodletools and how to properly cite your information. Remember, if you include ten pictures in a video, you need to cite them.
For all: Here is an audacity tutorial if you are interested in exploring it further.
All of you should read this report from the NY Times about bullying. What can you do to make sure this is a safe school where things like this do not happen?
Posted by Mr. Schneider at 6:30 AM 0 comments
Thursday, March 20, 2008
All students will be working on their projects today.
Web 4 students should be exploring the idea of video. A new version of their thinkquest paragraphs should be submitted to me as well.
Web 1 and Web 2 students must answer the following on their blog today:
- What are the 3-5 main points that answer your question?
- Include at least one link to your primary, or best source.
At this point Web 1 and Web 2 students will be locked into their topic. No more switching.
Posted by Mr. Schneider at 6:33 AM 0 comments
Wednesday, March 19, 2008
Today Web 1 and Web 2 will review Movie Maker. Short, 30 second movies can be powerful vehicles for your message. Each of these videos has over 3000 views.
Posted by Mr. Schneider at 8:23 AM 0 comments
Tuesday, March 18, 2008
Blog Entries
Web 4:
Please evaluate your rough draft using the language from the evaluation criteria. You should focus on between 5-7 of the bulleted points. Please include points that you think you did well on, and points you think you must improve over the next week. Your blog entry should be formatted using bullets (unordered list: UL).
It is important to take time to reflect on your work before we jump ahead for the final draft. Take the time to analyze your work so you can build on your strengths and try to improve your weaknesses.
Web 2 and Web 1:
Please submit a blog entry that answers the following questions:
- Which topic will you choose? Why?
- You have looked at several examples. List 3-5 characteristics of a successful exam.
- What will be your biggest challenge for this exam (research, technical things, etc...)??
Posted by Mr. Schneider at 7:03 AM 0 comments
Monday, March 17, 2008
Today we will launch the exams for Web 1 and Web 2.
Both Web 1 and Web 2 have the same exam questions. If you were in my class for Web 1 you will recognize the format and questions. I repeat the questions on purpose. I want to see how you have developed your design skills and techniques.
This is a serious research project. You will need to follow directions and be sure to cite your work correctly.
In conjunction with the project I will be doing a series of short demonstrations of programs we have on your computer. You might decide to incorporate these techniques into your project.
Of course, our baby is still due. So soon I will need to take care of that. Hopefully I can make it through today and fully explain the exam.
Posted by Mr. Schneider at 6:33 AM 0 comments
Tuesday, March 11, 2008
Due Dates
Any work for Project 3 (including quiz) will be due by the end of class on Friday. No exceptions!
If you are in Web 1 you should not move on to Project 4. Help your classmates get done.
If you are in Web 2 then you SHOULD move on to Project 4. I will add more notes later but let it be known that the Flash buttons will probably not work in this project.
Web 4? Tick tock tick tock. Monday's rough draft deadline approaches.
Get it done.
Posted by Mr. Schneider at 12:52 PM 0 comments
Monday, March 10, 2008
Some interesting articles this weekend in the NY Times. Please be sure to write or comment about one, or all, of these articles in your blog.
The first is about athletic scholarships for college and all the misinformation that is out there. Athletes are continually surprised at how many scholarships are actually out there. I can't tell you how many times I hear of coaches or trainers saying they have the "secrets" for getting scholarships.
A second article is the growing trend of academic scholarships. This was talked about by the coaches in the first article, that you have a MUCH better chance of getting a full ride academic scholarship. MIT just announced that if your family income is under $75,000 per year that they will waive tuition for accepted students. Several other schools have adopted similar programs.
Finally, there is an article about paying students to excel. This article focusses on younger students. Many people object to this idea, that students should receive cash for getting high marks. However, I do see some inconsistencies as we certainly support "paying" students by giving academic scholarships.
And, this one is just for fun. What do you think about texting?
So, what do you think? Be sure to include links to the articles in your blog entry. Web communications is about taking many sources and forming your own message. This is how we practice. Your article should be a few paragraphs long (at least) and should invite more conversation. If people leave comments, then you made a good article.
Posted by Mr. Schneider at 6:53 AM 0 comments
Monday, March 03, 2008
Web 1 and Web 2 students should be working on Project 3. If you finish Project 3 please do not move on to project 4 yet. We do several activities (including a big exam) between these projects.
If "done" please work on:
1. Web2 Quiz.
2. Web 1 Quiz. Take your quiz from Project 1 (your class schedule). Code this project again, but use tables to format the page and your schedule.
3. Blog connections. Several of you choose colors on your blog that are hard to read like this or this . Please change this!!
Posted by Mr. Schneider at 6:48 AM 0 comments


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SOURCE: LexisNexis HPCC
May 17, 2013 12:07 ET
ATLANTA, GA--(Marketwired - May 17, 2013) - LexisNexis Risk® Solutions today announced the program schedule for the First International Symposium on Big Data & Data Analytics in Collaboration (BDDAC), held in conjunction with the 2013 International Conference on Collaboration Technologies and Systems, May 20-24, 2013, in San Diego. LexisNexis and its team from HPCC Systems®, an open-source, enterprise-proven platform for Big Data analysis and processing, are bringing together big data and academic experts from leading organizations and universities across the country and abroad.
"The research and academic communities, government organizations and leading companies in the Big Data field are key to the innovation in technology required to solve today's societal challenges," said Flavio Villanustre, Vice President, Information Security, LexisNexis, and symposium organizer. "It is this type of collaboration that fuels the evolution of information technology. We appreciate everyone's contribution to make this forum a reality for organizations looking to extract better insights from Big Data."
The First International Symposium on Big Data and Data Analytics in Collaboration (BDDAC 2013) Program Schedule:
Speaker: Peter Kogge, University of Notre Dame and EMU Solutions, Inc., Indiana, USA
"Big Data" traditionally refers to some combination of high volume of data, high velocity of change, and/or wide variety and complexity of the underlying data. Recently, a growing number of "Deep Data" problems have arisen where it is the relationships between objects, and not necessarily the collections of objects, that are important, and for which the traditional implementation techniques are unsatisfactory. The goal is to discover, to at least a first order approximation, what are the tall poles preventing a speedup of their solution.
Panel Speakers:
Have you wondered why there is so much data and why it is growing so fast? Companies have been collecting data for years in transaction systems. The adoption of mobile phones and the expansion of the Internet are leading to every machine becoming a node on the Web, relentlessly generating data! The moderator will engage a panel of data scientists and researchers into a discussion on the best tools and approaches for studying social media data and understanding the difference between "tons of data" and "meaningful information derived from data." Panelists will share their insights and knowledge on how new technologies are helping to drive decision-making, uncover patterns and reveal relationships that never before could have been obtained.
Speakers: Siddhartha Bagaria, Staff Scientist; Richard Palmer, Principal; and Jacob Spoelstra, Global Head of R&D, Opera Solutions, LLC
Volume and velocity are two of the three V's that define Big Data. This is especially true in the global travel industry, where billions of messages are being passed between travel agents and travel providers on a continual basis, arriving at rates of hundreds/thousands per second (this includes for example availability requests, rate information, bookings, changes to booking and cancellations.) This presents a challenge for traditional Business Intelligence reporting. This case study discussion will describe the approach, the technology used, results obtained and lessons learned.
Speakers: Zack Bennett, Consulting Computational Linguist, and Marc G. L'Heureux, Senior Computational Linguist, LexisNexis
This case study examines how the legal and professional business of LexisNexis uses scaled active learning on the HPCC Systems environment to focus manual topical annotations on critical documents pulled from a large corpus powering its content and technology solutions. The active learning system uses natural language processing and machine learning techniques to identify and present "next best" training set candidates to legal editors, combining massive parallel processing with expert human analysis to improve classifier accuracy while minimizing human effort.
Mary Galvin of LexisNexis Special Services Inc. will also present a demo session at CTS 2013 on Smart View™ Entity Resolution. This demo highlights how data scientists can gain new, deeper insights into entities of interest across "big" datasets; all without needing to attempt to integrate separate, disparate technologies for data processing, entity resolution, and data enrichment. Using Smart View's unique, statistical approach, combined with an easy-to-use interface and powerful visualization features, offers a compelling solution, data scientists can tackle their organization's internal entity resolution challenges.
Participants on the BDDAC 2013 International Program Committee can be found here.
LexisNexis offers free, online introductory programming classes to learn HPCC Systems, designed for professional and student developers and the academic community. For more information, visit http://learn.lexisnexis.com/hpcc.
About HPCC Systems®
HPCC Systems® (www.hpccsystems.com) from LexisNexis® Risk Solutions offers a proven, data-intensive supercomputing platform designed for the enterprise to process and solve Big Data analytical problems. As an alternative to legacy technology, HPCC Systems offers a consistent data-centric programming language, two processing platforms and a single, complete end-to-end architecture for efficient processing. Connect with us on Twitter (@hpccsystems), Facebook (https://www.facebook.com/hpccsystems) and LinkedIn (http://www.linkedin.com/company/hpcc-systems)
About LexisNexis Risk Solutions
LexisNexis® Risk Solutions (www.lexisnexis.com/risk/) is a leader in providing essential information that helps customers across all industries and government predict, assess and manage risk. Combining cutting-edge technology, unique data and advanced scoring analytics, we provide products and services that address evolving client needs in the risk sector while upholding the highest standards of security and privacy. LexisNexis Risk Solutions is part of Reed Elsevier, a leading publisher and information provider that serves customers in more than 100 countries with more than 30,000 employees worldwide.
Media Contact
Jill Ratkevic
Black Swans Media for LexisNexisEmail Contact
Media Contact
Jill Ratkevic
Black Swans Media for LexisNexisEmail Contact
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Visiting the Middle of the World!
On my wonderful trip to Quito, Ecuador, I was given the opportunity to visit the Middle of the World Monument and the Intiñan Solar Museum. Both places are a must visit while you are in the area of Quito. The … Continue reading
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Thyroid gland diseases
Thyroid gland diseases. The diagnosis, the differential diagnosis, preventive maintenance and treatment of goiter
Iodine deficiency diseases (IDD) are pathological states caused by reduced iodine contains in organism. About 740 million of the world population are ill with IDD.
kinds of IDD:
Ø Hypothyroidism,
Ø Diffuse euthyroid goiter or nontoxic,
Ø Nodular and multinodular euthyroid goiter,
Ø Functial autonomy of the thyroid gland.
The main phatology is Goiter – diffuse. Now we use modern classification of increasing of the thyroid gland.
Degrees of Thyroid Gland Size Abnormalities
· 0 degree - goiter is hidden and not palpable;
· I degree - goiter is palpable, but hidden; or one or more nodules are palpable in the thyroid gland;
· II degree - goiter is palpable and visible.
Factors of Etiology.
- Main factor is iodine insufficiency, f.e. in water, in food
- Goitrogenes factors, which inhibit transportation of iodides to the thyroid gland
- Low level of microelements, such as Zn, Co, Se, Mg, Cu and high level of Ca
- Ionize radiation and environment pollution with radionuclides
- Infectious diseases
- Helmintic invasion
- Lack of Vitamin A - reduction
- Hereditary factors connected with disorders of syntheses thyroid hormones
Differenceeted natural stumogenes of food products contained in tapioca, soy, peanut, turnip. Some flavonoids provoked disorders of metabolism iodine, f.e. african millet, sorghum, bobs.
What do analysis of presence of iodine deficiency? Analyses of iodine deficiency can be made according to concentration of iodine in urine. There are some degrees of iodine deficiency:
Endemic goiter severity criteria (WHO, 1994)
Indices, at children and adults
Severity degree
goiter rate during palpation(%)
less than 5
more than 30
Thyroid gland volume rate more than 97 percentiles (%)
less than 5
more than 30
Median of iodine excretion with urine (ug/1)
more than 1 00
less than 20
Median of thyroglobulin concentration in blood (ng/ml)
less than 10
more than 40
Median of TSH level in blood more than 5 mu/1 newborns), %
less than 3
more than 40
The Iodine Deficiency caused the secretory ability of the thyroid gland and promotes goitrogenesis. The decrease of thyroid hormone in blood leads to increasing of TSH hormone production and to the development of iodine deficiency hypothyrosis. As a result it promotes follicles hypertrophy, strengthening of bloodstream in a gland and iodine absorption - compensatory mechanisms. After that thyroid gland hyperplasia develops. This adaptive mechanisms allow to support an euthyroidism for the long time in the conditions of insufficient iodine supply. Goiter, as the basic manifestation of iodine insufficiency, is also a display of adaptation possibilities of organism.
Thyroid hormone increases in pubertal age, during pregnancy, at the serious somatic or infectious diseases. At this situations develop hyperplasia thyroid gland acquires a nodular character. Nodules and adenomas appear in a gland. A diffuse endemic goiter grows into diffuse-nodular goiter. Adenomas and nodules are able to grow into thyrotoxic in case of sufficient iodine supply. Iodine-induced thyrotoxicosis develops following this mechanism. In these conditiones functional autonomy of the thyroid gland is developing. At iodine deficiency, number of autonomously-functioning thyrocytes is increasing, they formed into nodular and multinodular forms, often with thyrotoxicosis.
In pathogenesis of clinical displays of endemic goiter certain role is played by natural immunity inhibition.
Clinical features.
Appear increasing of thyroid gland. The degree of increasing can be different. Usually the increase is diffuse, but sometimes it is diffuse-nodular. With mild and moderate iodine deficiency the increase of the thyroid gland takes place slowly, achieving maximal sizes during 10-15 years and more. Clinically the goiter is usually euthyroid, with gradual development of the hypothyroidism.
Goiter is only the external display of iodine deficiency. Clinical features are caused by a hypothyroidism. Fatigue, deceleration of psychical reactions, dysmenorrhea, galactorrhea, abnormalities of the reproductive ability arc connected with hypothyroidism.
Characteristic signs of hypothyroidism:
• constipations,
• physical and mental fatigue,
• somnolence, chillness,
• growth of body weight,
• anemia.
In severe cases endemic cretinism develops which is manifested by disorders of the nervous system.
Diagnosis. - Thyroid hormones in blood is decreasing.
- TSH in blood plasma is increasing.
- Goiter size.
- Testing of ioduria.
- Ultrasound examination of the thyroid gland enables to determine its size and presence of nodules.
On indication: - Nodules formations are punctuated.
- Scanning with radioactive iodine.
1. Diffuse endemic goiter prescribe iodides in daily dose up to 200μg, in case of a big goiter (2nd degree) L-thyroxin is prescribed to decrease TSH concentration in blood. The dosage of L-thyroxin is from 25 to 100 μg per day. Patient's condition must be strictly monitored and controlled to achievement an euthyroidism.
Surgical intervention is necessary for patients with large goiters or in case of presence syndrome of compression and dysfunction.
2. Nontoxic Nodular and Multinodular goiter. There are three methods of treatment: surgical, medicamental, and active supervision of the nodule.
- Medical tactics depends on functional condition of the nodule, cellular compound, growth velocity. The medicamental treatment of nodular goiter by L - thyroxine is applied in case of hypothyrosis. The purpose of the treatment is a replacement therapy, achievement of euthyrosis, inhibition of further enlargement of nodes.
- Surgery is applied in case of node malignization, autonomic adenomas, quickly enlarged retrosternal nodes, compression of trachea or esophagus, mediastinum.
- Active supervision is applied to patients with nodes (10-30 mm in diameter) without signs of proliferation, which does not enlarge during dynamical ultrasound investigation, usually these are mature and elderly people.
Iodine deficiency may be prevented by realizing mass, group and individual iodine prophylaxis.
Mass prophylaxis is carried out for all inhabitants of an iodine deficient area. Iodized salt consumption is a tried and tested method. Iodination is made by using potassium iodide, 20 -40 mg/kg of salt, that provides matriculation of 150 μg of iodine every day. For mass prevention oily dine solution (lipiodol) is also used. Ingestion of this product provides a body with a sufficient amount of iodine for 6 to 12 months and intramuscular introduction - for 1 to 3 years.
For individual and group prevention iodine preparations are used, primarily antistrumin, 1 tablet 1-2 times a week, as well as iodides (Iodide-Farmak, IodBalance and Iodomarin) -10 and 200 μg in tablets.
Group prevention is an additional introduction of iodides on the back-ground of the mass prophylaxis for the categories of people with an increased iodine requirement: pregnant women, nursing mothers, adolescents.
Individual prevention is prescribed to some patients in case of an increased iodine requirement. These patients will include: women one year before a scheduled pregnancy, recovers after severe somatic or infectious diseases, after antibiotic therapy courses or sulfonamide treatment, persons with affected alimentary organs, if abnormal iodine absorption may occur.
Iodine requirement for different age categories
Children under 1 years old
50 μg/day
Children 1-6 years old
80 μg /day
Children 6-12 years old
120 μg /day
Children older than 12years old
and adults
150 μg /day
Pregnant women and
nursing mothers
150 to 200 μg /day
Thyrotoxicosis (synonym: Basedow's, Graves' s - diffuse toxic goiter) is a disease characterized by excessive production of thyroid hormones (hyperthyroidism) and by diffuse enlargement of the thyroid gland. Changes in other organs caused by influence of thyroid hormones and autoimmune disorders.
Graves' disease is mostly a disease of women of 20-50.
Thyrotoxicosis occurs in consequence of the thyroid-stimulating globulins formation, which compete with TSH receptors on a surface of thyreocytes and induce a cell growth and excessive secretion of thyroid hormones.
Factors that lead to autoimmune disorders can be:
§ excessive amount of iodine,
§ treatment by lithium,
§ infectious diseases (a flu, quinsy, chronic tonsillitis, a scarlet fever, whooping cough, rheumatism, encephalitis).
Some viruses can form complexes with thyreocytes surface proteins, changing its structure and antigenic characteristics.
As provocative moments of disease manifestation can act
• an excessive insolation,
• a mental trauma,
• pregnancy and postnatal period.
Thyrotoxicosis is classified as a disease which develops due to the mechanism of hypersensitivity of the slow type.
Genetic defect is located in organ-specific CD-8 - lymphocytes (T-supressors). Because of the suppression of "forbidden" T-lymphocytes clones is not carried out they survive and cooperate with organ-specific antigenes of a thyroid gland.
Clones of lymphocyte that are sensibilized to the antigenes of a thyroid gland stimulate B-lymphocytes to synthesis of antibodies to thyroid-stimulating hormone receptor. Thyroid-stimulating immunoglobulins of class G cooperate with follicular epithelium receptors and induce thyreocytes to excessive production of thyroid hormones and to hypertrophy and hyperplasia.
It is impossible to explain completely a pathogenesis of diffuse toxic goiter by action of thyroid-stimulating immunoglobulins. They are also found at subacute and autoimmune thyroiditis. In these cases they do not stimulate but depress the function of a thyroid gland. In pathogenesis of a diffuse toxic goiter a major importance is given to lymphocytic infiltration of the gland which produces a tumor necrosis factor and alpha interferon.
Pathogenesis of clinical symptoms of diffuse toxic goiter is connected with increased cathabolic impact of excessive amount of thyroid hormones.
Clinical features.
Most prominent clinical symptoms of disease are:
- increasing irritability,
- nervousness,
- tachycardia,
- weight loss with normal nourishment,
- weakness,
- a tremor of all body,
- sweating,
- heat intolerance,
- diarrhea,
- tearfulness.
The skin is wet and warm. In some patients an uneven hyperpigmentation of all body is observe. In some patients a pretibial swelling (thyroid acropathy, pretibial myxedema) is observed. The skin is characterized by swelling of pretibial areas, brownish in color.On feet the leather skin is horned, crawls over phalanxes of fingers.
The eyes signs are characteristic to the majority of patients with a diffuse toxic goiter – Ophtalmopathia.
v Palpebral fissures are widely opened with expression of surprise - Delremplin's symptom.
v The exophtalmus is determined, more often on both eyes. Exophotalmus can affect one eye, for instance a rare winking - Shtelwag's symptom;
v Retraction of upper lid, owing to what during the movement of an eyeball downwards between upper lid and an iris appears a white strip of sclera - Gref's symptom or during the movement of an eyeball upwards - Coher's symptom.
v Disorders of convergence of eyeballs is called - Moebius's symptom.
The most typical clinical symptoms of thyreotoxicosis are changes in cardiovascular system. The most common is sinus tachycardia. The pulse rate reaches 100 beats per a minute and more. May be: - extresystole,
- atrial fibrillation.
Symptoms of thyrotoxicosis and their frequency
Frequency (%)
Heat intolerance
Increased systolic blood pressure
Weight loss
Muscle weakness
Eye signs
Increased appetite
Atrial fibrillation
Pretibial myxedema
The systolic blood pressure increased and diastholic blood pressure is reduced. It is connected with increase cardiac output (systolic blood pressure) and peripheral vasodilatation (diastolic blood pressure). Borders of relative heart dullness are displaced to the left, heart tones are loud and strengthened. A systolic murmur may be often heard. The origin of murmur is connected with enlargment of atrioventricular ostiums and bloodstream acceleration. The gemodinamic changes includes increased stroke and minute volumes of bloodstream, volume of circulating blood, bloodstream. Heart insufficiency develops in 15-20 % of cases, mainly in patients with atrial fibrillation. Thyreotoxic cardiomiopathy develops under influence of excessive amount of thyroid hormones and catecholamines, which received a clinical name «hyperthyroid heart».
Electrocardiographic examination shows the signs of a left ventriclar hypertrophy. High waves R, S and T, shortening of interval S-T, sinus tachycardia are fixed. As soon as heaviness of «hyperthyroid heart» increases the waves size decreases and wave T becomes twophase or negative, the depression of S-T segment and atrial fibrillation are observed.
Changes of muscular system are shown by thyrotoxic miopathy. Significant muscular.
Half of patients suffer from changes of digestive system. Defecation becomes more frequent, it can be up to 20 times a day. Weight loss is one of the most typical symptom of thyrotoxicosis. It is caused by increased catabolism due to high amount of thyroid hormones.
Characterize presents of psychic and nervous symptoms in clinical picture, f.e. a nervous hysteria. Patients appear to be nervous, anxious, irritate with no reason, start crying. Changes of mood are often. Tremor of fingers of the extended hands (Mari's symptom) is typical. Tremor is constant. In case of serious clinical course of thyrotoxicosis depression, delirious conditions and delirium are possible.
On the part of skeletal system an intensification of osteoporosis is possible as a result of stimulating impact of thyroid hormones on osteoclasts.
Dysfunction of other glands of internal secretion, in particular, reproductive glands is frequently observed during thyrotoxicosis. Half of women with thyrotoxicosis have deranged menstrual cycle and dysmenorrhea. In case of mild forms of thyrotoxicosis menorrhea. The menstrual cycle becomes single-phase with insufficiency of lutein phase.
Males has atrophic changes in testis, prostate gland, reduced libido and potency. These specified symptoms are temporal, reverse development occurs after the liquidation of thyrotoxicosis.
Function of adrenal glands is intensified, as a result - hypocorticoidism develops, and chronic suprarenal insufficiency (Addison's desease).
Patients with thyrotoxicosis may have reduce tolerance to carbohydrates even to development of a diabetes.
The thyrotoxic crisis develops within several hours to one day.
· Excitation increases
· Tachycardia - 200 beats per a minute
· Extrasystole
· Atrial fibrillation
· Systolic arterial blood pressure increases
· Diastolic arterial blood pressure decreases.
· Sweating is increased
· The skin is warm and wet to touch
· The body temperature increases and can arise up to 40 °C
· Psychical and emotional excitation
· Psychical excitation - acute psychosis with a disorientation, delirium, hallucinations
· The diarrhea
· Vomiting
· Muscular weakness up to adynamia
· Patients can lose consciousness - Thyreotoxic coma
· Other complectation - acetone appears, ketonurine
· Acute hepatic insufficiency
· Reduction of diuresis up to anury
· The systemic alkalosis, hypokaliopenia
Diagnosis is based on the establishment of excessive production of thyroid hormones (hyperthyroidism) and on diffuse enlargement of the thyroid gland.
The most typical clinical signs are:
- excitability,
- irritability,
- weight loss,
- weakness,
- tachycardia,
- atrial fibrillation,
- sweating,
- tremor of all body.
A goiter in a patient diffuse hyperplasia
Functional activity of a thyroid gland
1. Level of thyroid hormones increased.
2. Depression of TSH.
Thyroid gland volume is determined by ultrasound studies. In case of toxic goiter a thyroid gland is diffusely enlarged.
Thyrotoxicosis can be treated by medications, surgery or by using a radioiodine.
Antithyroid drugs is always used - mercasolile, thyrosol, thiamazole, metisole. These medicaments block formation of organic iodine in a thyroid gland, they inhibit the process of condensation of iodotyrosines into triiodothyronine and thyroxine.
In case of intolerance to mercasolil, other medicaments with thyrostatic actions are prescribed,
a) iodides,
b) Lughole's iodine solution is prescribed up to 50 drops a day.
Beta-blockers are prescribed with antithyroid medicaments.
· propranolol is 120 mg per day
· atenolol (50-100 mg per 24 day),
· metoprolol (100-200 mg per day),
· bysoprolol (5-10 mg per day).
Glucocorticoids can be also used in case of relative suprarenal insufficiency. The prednisolonum is prescribed in an initial dose of 20-30 mg, reducing each five days to 5 mg or other glucocorticoids in an adequate dose.
Treatment of a thyrotropic crisis includes:
-Elimination of provoking factors (whenever it is possible);
-Blockade of thyroid hormones synthesis;
-Blockade of peripheral action of hormones;
-Maintenance of vital functions of an organism;
-Removing thyroid hormones and thyroidstimulating immunoglob-ulines from an organism.
Blockade of thyroid hormones synthesis is reached by oral introduction of mercasolil or through nasogastral probe. Initial dose of mercasolil is 60 mg, further dose is 30 mg each 4 hours. Preparations of iodine are prescribed in 2 hours after introduction of mercasolil. It excludes use of iodides for thyroid hormones synthesis.
Intravenous drip-feed of 1000 ml of 5 % solution of glucose with 1 ml of Lughole's iodine solution is prescribed. 10 % natrium iodides solution is injected, by 1 ml intravenously each 3 hours. Lughole's iodine solution can be given by oral introduction or through nasogastral probe by 30—40 drops each 3 hours.
Peripheral action of hormones is blocked by B-blockers, that is why a pro-pranolol is injected intravenously from 1 up to 3 mg each 3 hours. Glucocorticoids are also intravenously dropwise injected. Hydrocortison is prescribed up to 500 mg per day or prednisolonum - 200 mg per day, dexamethazon up to 20 mg per day. Strengthening of thyroid hormones excretion from an organism is reached by assignment of phenobarbital, in dose up to 200 mg per day.
Body temperature of patients is reduced by covering them with bubbles of ice, cold blowing, by assignment of acetoamiphenum (paracetamol).
Excessive amount of thyroid hormones released from an organism with the help of plasmapharesis, hemadsorbtion. The water regimen of an organism is supported by introduction of a 5 % solution of glucose and 0.9 % solution of natrium chloridis.
Hypothyroidism is a disease, caused by a persistent reduction of thyroid hormone impact on a target organs.
Nowadays the following forms of hypothyroidism are distinguished:
1. Primary hypothyroidism – as a result pathology in a thyroid gland.
2. Central hypothyroidism (hypothalamic-pituitary). Hypothyroidism develops due to a defeat of a pituitary gland (secondary hypothyroidism) or hypothalamus (tertiary hypothyroidism).
3. Peripheral hypothyroidism, caused by resistance of tissues to thyroid hormones action
4. Subclinical hypothyroidism is a syndrome, which is characterized by increasing plasma level of TSH on a background of a normal level of thyroxine and triiodothyronine.
5. Transient hypothyroidism. Hypothyroidism, which developed on a background of some diseases (conditions) or reception of medical preparations and inclined to spontaneous disappearance of its displays after elimination of etiological factors.
It is known that primary hypothyroidism makes approximately 95 % of all cases of hypothyroidism. Often it is an outcome of autoimmune thyroiditis, it may be a display of congenital defects of thyoroid hormones biosynthesis, the heaviest iodine deficiency, medicamentous or toxic effects.
The pathogenetic basis of hypothyroidism is an disorder of metabolism. Metabolism is reduced, especially in organs and tissues, which quickly grow and updated:
• erythropoesis is slowed down and anemia occurs
• Free fatty acids, triglyceridis, cholesterol are collected in organism because of lipids metabolism delay
• Proteins metabolism - accumulation of glycosaminglycans - a mucinous swelling.
Clinical features.
The disease develops slowly and gradually. Weakness, drowsiness, sluggishness, memory impairment, chill, constipations are typical complaints of patients. Frequently patients with anemias.
Clinical symptoms
Frequency %
Dryness of the skin
Speech delay
Face puffiness
Increased tongue
Hair loss
Increased borders of relative heart dullness
Memory impairment
Pallor of a skin
Yellowish discoloration of the skin
Weight increase
Lack of breathe
Hoarseness of the voice
Hearing impairment
Cardiovascular system. Abradycardia in case of a significant anemia tachycardia occurs. The borders of relative heart dullness are displaced due to dystrophic changes in myocardium and accumulation of liquid in a pericardium. The diastolic pressure increases. On electrocardiography the interval R-R is increased, voltage of waves is reduced, there can be a depression of S-T segment, inversion of T wave.
Significant changes in gastrointestinal system are observed. A decreased motility of the. The tongue is increased. The secretion is decreased, the absorption of vitamin B12 is disturbed, this process aggravates anemia.
Essential changes are revealed in nervous system, both in peripheral and in central. A hypothyroid patient is slow in thought, they less able to concentrate and memorize. The mental potential of a person decreases. Some of patients feel fears, disturbing-depressive syndrome is formed.
Changes in peripheral nervous system –as a result tunnel syndrome.
The bronchitis and prolonged pneumonias are.
The changes of muscles and joints - edema of synovial structures and capsules of joints of hands and legs – as a result pseudomyopathic syndrome occurs.
Anemia – decrease of hemoglobin synthesis, reduction of iron absorbtion in digestive system, vitamin Bp and folic acid deficiency.
Myxedema coma.
The reason of its development is untreated hypothyroidism.
Reasons: - cold exposures,
- respiratory diseases,
- surgical interventions,
- narcosis,
- food and medicamental intoxications,
- medical drugs, that oppress central nervous function (neuroleptics, tranquilizers, sedatives).
In patogenesis : - hypercapnia,
- hypoxia,
- water and electrolytic imbalance,
- hypothermia.
Hypoxia is caused by pulmonary hypoventilation. Adiposity, edema of body, hydrothorax, ascites, mucinous swelling of alveoluscs promote hypoxia development. Decreas of kidney's bloodstream - hypercapnia - coma develops gradually.
Clinic features.
· Weakness,
· Apathy,
· Drowsiness occurs,
· Movements become slower.
Appearance of patients with hypothyroidism is rather specific: puffy face with specially strongly pronounced swelling lips, ears and eyelids. The skin is dry, pale, rough with scales and it feels cold. The skin practically can not be taken in folds because of significant mucinous swelling.
The body temperature is reduced. Bradycardia. Boundaricss of heart dullness arc displaced.
Diagnosis and the differential diagnosis.
Ø Hypothyroidism is diagnosed on its clinical symptoms and laboratories results of hormones in plasma of blood.
Ø Reduction of triiodothyronine
Ø Thyroxine and increasing of TSH.
Instrumental diagnostics.
Ø Increased time of Achilles tendom reflex - the limits of 270 ± 30 Msec.
Ø An atrophy of a thyroid gland - ultrosound.
Hypothyroidism is treated by synthetic analogues of thyroid hormones: Levothyroxine and Liothyronin. There are also combined preparations of Levothyroxine with Liothyronine and a potassium iodide (Thyrocomb, Thyrotom, Novothyral e.a.)
Thyrocomb (70 ug of the Levothyroxine, 10 ug of the Liothyronine, 160 ug of the potassium iodide).
Thyrotom (40 ug of the Levothyroxine, 19 ug of the Liothyronine).
Thyrotomorte (120 ug of the L-thyroxine, 30 ug of the L-triiodothyronin).
Novothyral (120 ug of the Levothyroxine, 20 ug of the Liothyronine).
Euthyrox with 25, 50, 75, 100, 125, 150, 175, 200 ug of levothyroxine.
Levothyroxine is the most used preparation - for adults is 1.6-2.2 ug /kg/ per day. The treatment begins with 1/4 of a day.
Calculated dose increasing each 2 weeks twice and gradually leading up to a necessary effective therapeutic dose. The treatment begins from 25 ug of the Levothyroxine per day leading up to 100-150 ug per day. All the dose is taken in the morning after a breakfast. The efficiency of the treatment is estimated by a regress of clinical symptoms regression and normalization of the TSH.


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As many of our clients have expressed their desire to continue learning, and reading, about various topics covered in their Personalised Career Coaching sessions, we have created the lists below with our recommendations.
Clicking on either the picture or link provided will take you directly to the book's Amazon page, where you will be able to read more customer reviews, get a feel for the book with its sample pages, and even buy it if it interests you.
Give and Take: Why Helping Others Drives Our Success - Adam Grant
Give and Take: Why Helping Others Drives Our Success
For generations, we have focused on the individual drivers of success: passion, hard work, talent, and luck. But today, success is increasingly dependent on how we interact with others. It turns out that at work, most people operate as either takers, matchers, or givers. Whereas takers strive to get as much as possible from others and matchers aim to trade evenly, givers are the rare breed of people who contribute to others without expecting anything in return.
Using his own pioneering research as Wharton's youngest tenured professor, Adam Grant shows that these styles have a surprising impact on success. Although some givers get exploited and burn out, the rest achieve extraordinary results across a wide range of industries. Combining cutting-edge evidence with captivating stories, Grant shows how one of America's best networkers developed his connections, why the creative genius behind one of the most popular shows in television history toiled for years in anonymity, how a basketball executive responsible for multiple draft busts transformed his franchise into a winner, and how we could have anticipated Enron's demise four years before the company collapsed--without ever looking at a single number.
Named one of the best books of 2013 by Amazon, the Financial Times, and the Wall Street Journal- as well as one of Oprah's riveting reads, Fortune's must-read business books, and the Washington Post's books every leader should read. "Give and Take" highlights what effective networking, collaboration, influence, negotiation, and leadership skills have in common. This landmark book opens up an approach to success that has the power to transform not just individuals and groups, but entire organisations and communities.
Never Eat Alone: And Other Secrets to Success - Keith Ferrazzi
Never Eat Alone, Expanded and Updated: And Other Secrets to Success, One Relationship at a Time by Keith Ferrazzi (2014-06-03)
Do you want to get ahead in life? Climb the ladder to personal success?
The secret, master networker Keith Ferrazzi claims, is in reaching out to other people. As Ferrazzi discovered in early life, what distinguishes highly successful people from everyone else is the way they use the power of relationships —so that everyone wins.
In "Never Eat Alone", Ferrazzi lays out the specific steps —and inner mindset— he uses to reach out to connect with the thousands of colleagues, friends, and associates on his contacts list, people he has helped and who have helped him. And in the time since "Never Eat Alone" was published in 2005, the rise of social media and new, collaborative management styles have only made Ferrazzi's advice more essential for anyone hoping to get ahead in business.
The son of a small-town steelworker and a cleaning lady, Ferrazzi first used his remarkable ability to connect with others to pave the way to Yale, a Harvard M.B.A., and several top executive posts. Not yet out of his thirties, he developed a network of relationships that stretched from Washington's corridors of power to Hollywood's A-list, leading to him being named one of Crain's 40 Under 40 and selected as a Global Leader for Tomorrow by the Davos World Economic Forum.
Ferrazzi's form of connecting to the world around him is based on generosity, helping friends connect with other friends. Ferrazzi distinguishes genuine relationship-building from the crude, desperate glad-handing usually associated with "networking." He then distils his system of reaching out to people into practical, proven principles. Among them:
Don't keep score: It's never simply about getting what you want. It's about getting what you want and making sure that the people who are important to you get what they want, too.
"Ping" constantly: The ins and outs of reaching out to those in your circle of contacts all the time —not just when you need something.
Never Eat Alone: The dynamics of status are the same whether you're working at a corporation or attending a social event —"invisibility" is a fate worse than failure.
Become the "King of Content": How to use social media sites like LinkedIn, Twitter, and Facebook to make meaningful connections, spark engagement, and curate a network of people who can help you with your interests and goals.
In the course of this book, Ferrazzi outlines the timeless strategies shared by the world's most connected individuals, from Winston Churchill to Bill Clinton, Vernon Jordan to the Dalai Lama.
Chock-full of specific advice on handling rejection, getting past gatekeepers, becoming a "conference commando," and more, this new edition of Never Eat Alone will remain a classic alongside alongside How to Win Friends and Influence People for years to come.
Body of Work: Finding the Thread That Ties Your Story Together - Pamela Slim
Body of Work: Finding the Thread that Ties Your Career Together
These days it's increasingly rare to have a stable career in any field. More and more of us are blending big company jobs, startup gigs, freelance work, and volunteer side projects. We take chances to expand our knowledge, capabilities, and experience. But how do we make sense of that kind of career - and explain it? Pamela Slim, the acclaimed author of Escape from Cubicle Nation, gives us the tools to have meaningful careers in this new world of work. She shows how to find the connections among diverse accomplishments, sell your story, and continually reinvent and relaunch your brand.
Crossing the Unknown Sea: Work as a Pilgrimage of Identity - David Whyte
Crossing the Unknown Sea: Work As a Pilgrimage of Identity
"Crossing the Unknown Sea" is about reuniting the imagination with our day to day lives. It shows how poetry and practicality, far from being mutually exclusive, reinforce each other to give every aspect of our lives meaning and direction. For anyone who wants to deepen their connection to their life's work—or find out what their life's work is—this book can help navigate the way.
Whyte encourages readers to take risks at work that will enhance their personal growth, and shows how burnout can actually be beneficial and used to renew professional interest. He asserts that too many people blindly trudge through a mediocre work life because so many "busy" tasks prevent significant reflection and analysis of job satisfaction. People often turn to spiritual practice or religion to nurture their souls, but overlook how work can actually be our greatest opportunity for discovery and growth. "Crossing the Unknown Sea" combines poetry, gifted storytelling and Whyte's personal experience to reveal work's potential to fulfill us and bring us closer to ultimate freedom and happiness.
David and Goliath: Underdogs, Misfits and the Art of Battling Giants - Malcolm Gladwell
David and Goliath: Underdogs, Misfits and the Art of Battling Giants
What if everything we thought about power was wrong? What if, in the ancient story of the shepherd boy who topples a giant, David actually had the advantage?
Three thousand years ago on a battlefield in ancient Palestine, a shepherd boy felled a mighty warrior with nothing more than a pebble and a sling-and ever since, the names of David and Goliath have stood for battles between underdogs and giants. David's victory was improbable and miraculous. He shouldn't have won.
Or should he?
In DAVID AND GOLIATH, Malcolm Gladwell challenges how we think about obstacles and disadvantages, offering a new interpretation of what it means to be discriminated against, suffer from a disability, lose a parent, attend a mediocre school, or endure any number of other apparent setbacks.
In the tradition of Gladwell's previous bestsellers-The Tipping Point, Blink, Outliers and What the Dog Saw-DAVID AND GOLIATH draws upon history, psychology and powerful story-telling to reshape the way we think of the world around us.
This thought sets Malcolm Gladwell on an extraordinary journey that takes him from art to basketball, the brain to revolutions, along the way weaving unforgettable stories of misfits, outsiders, tricksters and underdogs who have faced outsized challenges and won. With his trademark warmth, humour and gift for showing us the world through new eyes, Gladwell lets us see why the powerful aren't always what we think they are - and that some of us have more strength and purpose than we could ever imagine.
Die Empty: Unleash Your Best Work Every Day - Todd Henry
Die Empty: Unleash Your Best Work Every Day
Most of us fill our days with frantic activity, bouncing from task to task, scrambling to make deadlines and chase the next promotion. But by the end of each day we're often left wondering if any of it really mattered. We feel the ticking of the clock, but we're unsure of the path forward.
"Die Empty" is a tool for people who aren't willing to put off their most important work for another day. Todd Henry explains the forces that lead to stagnation and introduces practices that will keep you on a true and steady course.
The key is embracing the idea that time is finite, so you should focus on the unique contribution to the world that only you can make. Henry shows how to sustain your enthusiasm, push through mental barriers, and unleash your best work each day.
Happier: Learn the Secrets to Daily Joy and Lasting Fulfillment - Tal Ben-Shahar
Happier: Learn the Secrets to Daily Joy and Lasting Fulfillment by Tal Ben-Shahar (2007-05-31)
Can we really learn to be happy? Yes, we can. Each semester, nearly 1,400 students sign up for Harvard professor Tal Ben-Shahar's life-changing class "How to Get Happy". Currently it's the hottest course at Harvard, taken by 20 percent of graduates.
In Happier, Professor Ben-Shahar brings the ideas of the Ivory Tower to Main Street, distilling the lessons and exercises from his course into an audio trove of practical wisdom. Grounded in the Positive Psychology movement, based on years of researching the works of scientists, academics, and philosophers, Happier emphasizes the importance of pursuing a life of both pleasure and meaning. Lessons, exercises, and "Happiness Boosters" cover self-esteem, empathy, friendship, love, achievement, creativity, spirituality, and humor.
I Could Do Anything If I Only Knew What It Was - Barbara Sher
I Could Do Anything If I Only Knew What It Was: How to Discover What You Really Want and How to Get It
If you suspect there could be more to life than what you're getting...if you always knew you could do anything if you only knew what it was, this extraordinary book is about to prove you right!
A life without direction is a life without passion. The dynamic follow-up to the phenomenal best-seller "Wishcraft, I Could Do Anything If I Only Knew What It Was" (the New York Times Bestseller) guides you, not to another unsatisfying job, but to a richly rewarding career rooted in your heart's desire. And in a work of true emancipation, this life-changing sourcebook reveals how you can recapture "long lost" goals, overcome the blocks that inhibit your success, decide what you want to be, and live your dreams forever!
You will learn:
* What to do if you never chose to be what you are.
* How to get off the fast track--and on to the right track.
* First aid techniques for paralyzing chronic negativity.
* How to regroup when you've lost your big dream.
* To stop waiting for luck--and start creating it.
Presence: Bringing Your Boldest Self to Your Biggest Challenges - Amy Cuddy
Presence: Bringing Your Boldest Self to Your Biggest Challenges
Have you ever left a nerve-racking challenge and immediately wished for a do over? Maybe after a job interview, a performance, or a difficult conversation? The very moments that require us to be genuine and commanding can instead cause us to feel phony and powerless. Too often we approach our lives' biggest hurdles with dread, execute them with anxiety, and leave them with regret.
By accessing our personal power, we can achieve "presence," the state in which we stop worrying about the impression we're making on others and instead adjust the impression we've been making on ourselves. As Harvard professor Amy Cuddy's revolutionary book reveals, we don't need to embark on a grand spiritual quest or complete an inner transformation to harness the power of presence. Instead, we need to nudge ourselves, moment by moment, by tweaking our body language, behavior, and mind-set in our day-to-day lives.
Amy Cuddy has galvanized tens of millions of viewers around the world with her TED talk about "power poses." Now she presents the enthralling science underlying these and many other fascinating body-mind effects, and teaches us how to use simple techniques to liberate ourselves from fear in high-pressure moments, perform at our best, and connect with and empower others to do the same.
Brilliantly researched, impassioned, and accessible, Presence is filled with stories of individuals who learned how to flourish during the stressful moments that once terrified them. Every reader will learn how to approach their biggest challenges with confidence instead of dread, and to leave them with satisfaction instead of regret.
Refuse to Choose!: A Revolutionary Program for Doing Everything That You Love - Barbara Sher
Refuse to Choose!: A Revolutionary Program for Doing Everything That You Love
Don't know what to do with your life? Drawn to so many things that you can't choose just one? New York Times best-selling author Barbara Sher has the answer―do EVERYTHING!
With her popular career counseling sessions, motivational speeches, workshops, and television specials, Barbara Sher has become famous for her extraordinary ability to help people define and achieve their goals. What Sher has discovered is that some individuals simply cannot, and should not, decide on a single path; they are genetically wired to pursue many areas. Sher calls them "Scanners"―people whose unique type of mind does not zero in on a single interest but rather scans the horizon, eager to explore everything they see.
In this groundbreaking book, readers will learn:
• what's behind their "hit and run" obsessions
• when (and how) to finish what they start
• how to do everything they love
• what type of Scanner they are (and which tools they need to do their very best work)
The Confidence Code: The Science and Art of Self-Assurance - Katty Kay
The Confidence Code: The Science and Art of Self-Assurance---What Women Should Know
Following the success of Lean In and Why Women Should Rule the World, the authors of the bestselling Womenomics provide an informative and practical guide to understanding the importance of confidence—and learning how to achieve it—for women of all ages and at all stages of their career.
Working women today are better educated and more well qualified than ever before. Yet men still predominate in the corporate world. In The Confidence Code, Claire Shipman and Katty Kay argue that the key reason is confidence.
Combining cutting-edge research in genetics, gender, behavior, and cognition—with examples from their own lives and those of other successful women in politics, media, and business—Kay and Shipman go beyond admonishing women to "lean in". Instead, they offer the inspiration and practical advice women need to close the gap and achieve the careers they want and deserve.
The Most Good You Can Do - Peter Singer
The Most Good You Can Do: How Effective Altruism is Changing Ideas About Living Ethically (Castle Lectures Series)
Peter Singer's books and ideas have been disturbing our complacency ever since the appearance of Animal Liberation. Now he directs our attention to a new movement in which his own ideas have played a crucial role: effective altruism.
Effective altruism is built upon the simple but profound idea that living a fully ethical life involves doing the "most good you can do." Such a life requires an unsentimental view of charitable giving: to be a worthy recipient of our support, an organisation must be able to demonstrate that it will do more good with our money or our time than other options open to us.
Singer introduces us to an array of remarkable people who are restructuring their lives in accordance with these ideas, and shows how living altruistically often leads to greater personal fulfilment than living for oneself.
"The Most Good You Can Do" develops the challenges Singer has made, in the New York Times and Washington Post, to those who donate to the arts, and to charities focused on helping our fellow citizens, rather than those for whom we can do the most good. Effective altruists are extending our knowledge of the possibilities of living less selfishly, and of allowing reason, rather than emotion, to determine how we live. "The Most Good You Can Do" offers new hope for our ability to tackle the world's most pressing problems.
The Slight Edge - Jeff Olson
"The Slight Edge" is a way of thinking, a way of processing information that enables you to make the daily choices that will lead you to the success and happiness you desire. Learn why some people make dream after dream come true, while others just continue dreaming and spend their lives building dreams for someone else. It's not just another self-help motivation tool of methods you must learn in order to travel the path to success. It shows you how to create powerful results from the simple daily activities of your life, by using tools that are already within you.
In this 8th anniversary edition you ll read not only the life-changing concepts of the original book, but also learn what author Jeff Olson discovered as he continued along the slight edge path: the Secret to Happiness and the Ripple Effect.
This edition of "The Slight Edge" isn't just the story, but also how the story continues to create life-altering dynamics how a way of thinking, a way of processing information, can impact daily choices that will lead you to the success and happiness you desire. "The Slight Edge" is the key that will make all the other how-to books and self-help information that you read, watch and hear actually work.
The Slight Edge - Jeff Olson
"The Slight Edge" is a way of thinking, a way of processing information that enables you to make the daily choices that will lead you to the success and happiness you desire. Learn why some people make dream after dream come true, while others just continue dreaming and spend their lives building dreams for someone else. It's not just another self-help motivation tool of methods you must learn in order to travel the path to success. It shows you how to create powerful results from the simple daily activities of your life, by using tools that are already within you.
In this 8th anniversary edition you'll read not only the life-changing concepts of the original book, but also learn what author Jeff Olson discovered as he continued along the slight edge path: the Secret to Happiness and the Ripple Effect.
This edition of "The Slight Edge" isn't just the story, but also how the story continues to create life-altering dynamics how a way of thinking, a way of processing information, can impact daily choices that will lead you to the success and happiness you desire. "The Slight Edge" is the key that will make all the other how-to books and self-help information that you read, watch and hear actually work.
15 Secrets Successful People Know About Time Management - Kevin Kruse
15 Secrets Successful People Know About Time Management: The Productivity Habits of 7 Billionaires, 13 Olympic Athletes, 29 Straight-A Students, and 239 Entrepreneurs
What if a few new habits could dramatically increase your productivity, and even 5x or 10x it in key areas? What if you could get an an hour a day to read, exercise, or to spend with your family? New York Times bestselling author, Kevin Kruse, presents the remarkable findings of his study of ultra-productive people.
Based on survey research and interviews with billionaires, Olympic athletes, straight-A students, and over 200 entrepreneurs—-including Mark Cuban, Kevin Harrington, James Altucher, John Lee Dumas, Pat Flynn, Grant Cardone, and Lewis Howes—-Kruse answers the question: what are the secrets to extreme productivity?
First Things First - Stephen R. Covey
Stephen R. Covey's First Things First is the gold standard for time management. His principle-centered approach for prioritising gives the reader the security to make changes and sacrifices needed in order to obtain happiness. The snapshots takes this philosophy and remasters with the entire text, and an addition of user friendly, clear and concise graphics. These added elements summarise and analyse all of the layers of behind the philosophy in an efficient manner while retaining the core message of time management and happiness.
Time Management: How To Get More Done in 5 Simple Steps - Hugo Gerard
Time Management: How To Get More Done in 5 Simple Steps.: Success Secrets & Habits You need to be More Productive
How can you practice the art of true time management and use it to free up your schedule? This book will help show you how to achieve superior efficiency in every area of your life, to make proper use of your time and of course, develop excellent time management skills.
When effective time management skills develop into a good habit, it is almost certain that your vision will become a whole lot clearer. What skills you'll learn when you read this book, - Planning and prioritizing your work - Types of scheduling lists - Organizing your environment - Focusing on what is important - And many other key-points to help you move forward.. "Small changes today are all you need to make, and that willingness to make it makes all the difference to you experiencing a whole new life ahead of you.
Born For This: How to Find the Work You Were Meant to Do - Chris Guillebeau
Born For This: How to Find the Work You Were Meant to Do
In "Born For This", Chris Guillebeau shows readers how to create their own self-styled career, offering a practical, step-by-step guide to finding work that feels so right it doesn't even seem like work.
Whether this is by launching a side job that turns a passion into a profitable business, winning the career lottery by finding a dream position within a traditional organization, becoming a DIY rock star by fashioning an entirely new profession around our varied interests, or hacking an existing humdrum job into work we will love, Guillebeau offers an actionable method and framework for turning our passions into paychecks.
Career Change: How To Conquer The Fear Of Failing - John Allen
Career Change: How To Conquer The Fear Of Failing
What's the first obstacle in changing career? Your own fear of change. This book uses practical exercises to help conquer this fear and get you started.
Nearly 90% of us work in a job that we don't enjoy. Even if the job is well paid, people are too scared to leave and try something different. This fear gets worse the older we get. Most career change books focus on training and skills, but they don't really talk about getting past the first major hurdle; a fear of change.
In this book, I take you through the ways you can confront your fear of change and get a career that's right for you…no matter how old you are.
Career Change: Stop Hating your Job - Joanna Penn
Career Change: Stop hating your job, discover what you really want to do with your life, and start doing it!
"Are you tired of asking "What should I do with my life?" Are you sick of your job? Don't worry, I know how you feel! I used to start every working week saying "I hate my job" and spend every Friday night drinking too much to drown my misery. I was a cubicle worker in large corporates, going to pointless meetings, writing endless documents no one would read, testing computer systems that would soon be obsolete. Every day, my soul and my creativity died a little. Maybe you feel the same? Well, life is too short to just exist on the edge of breakdown, and there is a better way of living. You need to discover what you love to do and then make that your job, your life's work. This book will take you through understanding the way you feel now as well as how to improve your current situation immediately so you can create enough space to work on breaking out and doing what you truly love. It also contains the career change process I used to go from management consultant to full-time author-entrepreneur. It's time to change your career and your life." - Joanna Penn
Day Job to Dream Job: Practical Steps for Turning Your Passion into a Full-Time Gig - Kary Oberbrunner
Day Job to Dream Job: Practical Steps For Turning Your Passion Into A Full-Time Gig
Are you squandering your talents in a job you don't love? Do you feel trapped and dissatisfied, afraid to risk your financial security to pursue your dream? The truth is you don't need an MBA, investors, or a lucky break to have the job you always wanted. With the right amount of knowledge, encouragement, and guts, anyone can make the leap from day job to dream job!
Through sharing his own story and the success of others who have followed his process, Kary gives you the tools you need to turn your passion into your full-time gig--starting now!
How to Get a Job You Love - John Lees
How to Get a Job You Love 2015-2016 Edition
How to Get a Job You Love, the UK's definitive careers guidebook, has undergone its biggest update in over a decade. This revamped and substantially updated edition reflects the latest changes in the rapidly evolving UK job market.
Put simply, How to Get a Job You Love provides all of the inspiration and motivation needed embark on a change of career, or to identify what sort of career you want in the first place. It's also packed full of practical hints, tips and useful resources.
Insightful exercises and activities guide the reader on a path of discovery to help identify their skills, passions and motivators and find ways to apply these to their professional and personal lives.
How to reinvigorate your work after the recession, particularly for those who have hidden in safe jobs
How to navigate the hidden job market through networking and social media
How to shorten the length of your job search
Brand new exercises to draw out your hidden skills and values
New insights into how employers prefer to recruit
Up-to-date interview tips from recruitment experts
Advice on how to perform well in your first 90 days in a new role
Luck Is No Accident: Making the Most of Happenstance in Your Life and Career - John Krumboltz
Luck is No Accident: Making the Most of Happenstance in Your Life and Career
Unplanned events—chance occurrences—more often determine life and career choices than all the careful planning we do. A chance meeting, a broken appointment, a spontaneous vacation trip, a "fill-in" job, a hobby—these are the kinds of experiences that lead to unexpected life directions and career choices.
Newly revised and updated with fresh examples and current issues for today's challenging times, Luck is No Accident actively encourages readers to create their own unplanned events, to anticipate changing their plans frequently, to take advantage of chance events when they happen, and to make the most of what life offers. The book has a friendly, easy style about it, and is packed with personal stories that really bring the ideas into focus.
What Color is Your Parachute? - Richard N. Bolles
What Color Is Your Parachute? 2016: A Practical Manual for Job-Hunters and Career-Changers
What Color Is Your Parachute? is the world s most popular job-hunting guide, revised and updated annually, with more than ten million copies sold. This 2016 edition features the latest studies and perspectives on today s job-market, including proven strategies for finding jobs even when everyone tells you there are none. Career expert Richard N. Bolles reveals surprising advice on what works and what doesn t so you can focus your efforts on tactics that yield results.
This helpful manual shares proven tips for writing impressive resumes and cover letters, as well as guidance for effective networking, confident interviewing, and the best salary negotiating possible. But it goes beyond that by helping you to zero in on your ideal job and life with its classic Flower Exercise. Whether you re searching for your first job, were recently laid off, or are dreaming of a career change, What Color Is Your Parachute? will guide you toward fulfilling and prosperous work.
Effective Leadership - John Adair
Effective Leadership (NEW REVISED EDITION): How to be a successful leader
Leaders play an essential role in every aspect of our modern lives and good leadership is an art that is highly prized. Effective leaders not only control, appraise and analyse, they also encourage, improve and inspire.
In Effective Leadership John Adair, Britain's foremost expert on leadership training, shows how every manager can learn to lead. Drawing on numerous examples of leadership in action – commercial, historical, military – he identifies the essential requirements for good leadership and explains how you can enhance your personality, knowledge and position to become the best leader you can be.
Recognized as the ultimate tool for any aspiring leader, this landmark book will help you to:
• Understand leadership – the characteristics and skills you need to be an effective leader
• Develop leadership abilities – how to define tasks, plan, brief, communicate, motivate and set an example
• Grow as a leader – how to put your leadership skills into practice
The 360 Degree Leader: Developing Your Influence from Anywhere in the Organization - John C. Maxwell
The 360 Degree Leader: Developing Your Influence from Anywhere in the Organization
Don't wait for that promotion! Start leading NOW...right where you are! What's the number one question leadership expert John C. Maxwell is asked while conducting his leadership conferences? "How can I implement what you teach when I'm not the top leader?". Is it possible to lead well when you're not the top dog? How about if the person you work for is a bad leader? The answer is a resounding yes!
Welcome to The 360 Leader. People who desire to lead from the middle of organizations face unique challenges. And they are often held back by myths that prevent them from developing their influence. Dr. Maxwell, one of the globe's most trusted leadership mentors, debunks the myths, shows you how to overcome the challenges, and teaches you the skills you need to become a 360 leader. If you have found yourself trying to lead from the middle of the organization, as the vast majority of professionals do, then you need Maxwell's insights. You have a unique opportunity to exercise influence in all directions-up (to the boss), across (among your peers), and down (to those you lead). The good news is that your influence is greater than you know.
A More Beautiful Question: The Power of Inquiry to Spark Breakthrough Ideas - Warren Berger
A More Beautiful Question: The Power of Inquiry to Spark Breakthrough Ideas
In this groundbreaking book, journalist and innovation expert Warren Berger shows that one of the most powerful forces for igniting change in business and in our daily lives is a simple, under-appreciated tool ―one that has been available to us since childhood. Questioning ―deeply, imaginatively, "beautifully"― can help us identify and solve problems, come up with game-changing ideas, and pursue fresh opportunities. So why are we often reluctant to ask "Why?"
Berger's surprising findings reveal that even though children start out asking hundreds of questions a day, questioning "falls off a cliff" as kids enter school. In an education and business culture devised to reward rote answers over challenging inquiry, questioning isn't encouraged―and, in fact, is sometimes barely tolerated.
And yet, as Berger shows, the most creative, successful people tend to be expert questioners. They've mastered the art of inquiry, raising questions no one else is asking―and finding powerful answers. The author takes us inside red-hot businesses like Google, Netflix, IDEO, and Airbnb to show how questioning is baked into their organisational DNA. He also shares inspiring stories of artists, teachers, entrepreneurs, basement tinkerers, and social activists who changed their lives and the world around them―by starting with a "beautiful question."
Berger explores important questions, such as:
- Why aren't we nurturing kids' natural ability to question―and what can parents and schools do about that?
- Since questioning is a starting point for innovation, how might companies and business leaders begin to encourage and exploit it?
- And most important, how can each of us re-ignite that questioning spark―and use inquiry as a powerful means to rethink and reinvent our lives?
"A More Beautiful Question" outlines a practical Why / What If / How system of inquiry that can guide you through the process of innovative questioning ―helping you find imaginative, powerful answers to your own "beautiful questions."
Scaling Up Excellence - Robert I. Sutton
In "Scaling Up Excellence", bestselling author Robert Sutton and Stanford colleague Huggy Rao tackle a challenge that determines every organisation's success: scaling up farther, faster, and more effectively as a program or an organisation creates a larger footprint. Sutton and Rao have devoted much of the last decade to uncovering what it takes to build and uncover pockets of exemplary performance, to help spread them, and to keep recharging organisations with ever better work practices.
Drawing on inside accounts and case studies and academic research from a wealth of industries – including start-ups, pharmaceuticals, airlines, retail, financial services, high-tech, education, non-profits, government, and healthcare -- Sutton and Rao identify the key scaling challenges that confront every organisation. They tackle the difficult trade-offs that organisations must make between "Buddhism" versus "Catholicism" -- whether to encourage individualised approaches tailored to local needs or to replicate the same practices and customs as an organisation or program expands. They reveal how the best leaders and teams develop, spread, and instil the right mindsets in their people -- rather than ruining or watering down the very things that have fuelled successful growth in the past. They unpack the principles that help to cascade excellence throughout an organisation, as well as show how to eliminate destructive beliefs and behaviours that will hold them back.
Scaling Up Excellence is the first major business book devoted to this universal and vexing challenge. It is destined to become the standard bearer in the field.
Amazon Best Books of the Year list, Business & Investing
Inc.com 10 Best Business Books of 2014
Financial Times - The Pick of 2014's Management Books
The Globe & Mail's list of 5 Best Business Books in 2014
Library Journal's list of 5 Best Business Books in 2014
Strategy and the Fat Smoker; Doing What's Obvious But Not Easy - David Maister
Strategy and the Fat Smoker; Doing What's Obvious But Not Easy
We often (or even usually) know what we should be doing in both personal and professional life. We also know why we should be doing it and (often) how to do it. Figuring all that out is not too difficult. What is very hard is actually doing what you know to be good for you in the long-run, in spite of short-run temptations. The same is true for organisations.
What is noteworthy is how similar (if not identical) most firms' strategies really are: provide outstanding client service, act like team players, provide a good place to work, invest in your future. No sensible firm (or person) would enunciate a strategy that advocated anything else. However, just because something is obvious does not make it easy. Real strategy lies not in figuring out what to do, but in devising ways to ensure that, compared to others, we actually do more of what everybody knows they should do.
This simple insight, if accepted, has profound implications for:
How organisations should think about strategy
How they should think about clients, marketing and selling
How they should think about management.
In 18 chapters, Maister explores the fat smoker syndrome and how individuals, managers and organisations can overcome the temptations of the short-term and actually do what they already know is good for them.
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Pétanque Courts
Towards the end of 2013 Pearl Valley constructed two pétanque courts. They are located next to the swimming pool and provide the perfect opportunity to spend some time outside with friends and family. The Pearl Valley Pétanque Association hosts monthly member competitions, which are well supported and enjoyed by many.


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The 5 Characters George R.R. Martin Wishes Game of Thrones Would Have Included
He says they still have a part to play in his books.
Just for fun, George R.R. Martin has taken to EW to talk about his favorite characters from his books that have been cut from Game of Thrones. Martin himself admits that the show could never have included the entirety of his massive cast list, which meant that important figures like "Nimble" Dick Crabb, Aenys Frey, and Dickon Manwoody failed to make the cut. Still, he says, among the missing there are five whose absences hurt most of all. (Spoilers within!)
Strong Belwas
In A Clash of Kings, Barristan Selmy enters Daenerys's service by disguising himself as the squire of Strong Belwas, a gigantic eunuch who used to duel in Meereen's fighting pits. Belwas is your classic "silly fat guy" — he loves to eat, he never wears a shirt, and, after one battle, he turns around and poops on the corpse of the man he just killed. In the books, he has a small role to play in the big fighting pit scene that's coming next week, but his main contribution is being a bit of fun in a part of the series that could definitely use it. "I understand why he was cut," says Martin, "but I kind of miss him."
Jeyne Poole
As you probably know by now, Sansa Stark was never married to Ramsay Bolton in the books. The unfortunate girl who was is Sansa's old friend Jeyne Poole, who was captured by the Lannisters at the end of the first book, taken in by Littlefinger, and forced to pose as Arya Stark in her wedding to Ramsay. Jeyne's fate is even more gruesome than Sansa's, so far: On their wedding night, Ramsay forces Theon to perform cunnilingus on her, and there are implications he makes Jeyne have sex with dogs. Martin apparently relished bringing back such a minor character in a major way, though he doesn't comment on the wisdom of changing Sansa's plot around.
Garlan and Willas Tyrell
In the books, Loras Tyrell is not the heir to Highgarden; he's only the third son, which makes his sexuality slightly easier for his family to swallow. His brother Garlan has only been seen briefly, while his oldest brother, Willas, hasn't appeared at all, but by all accounts, they're both solid dudes. Garlan is kind to both Sansa and Tyrion in their moments of need, and Willas is apparently one of the smartest men in Westeros. In spite of their lack of screen time, Martin insists they've got important roles to play in The Winds of Winter: "I didn't just throw them in for hoots and giggles."
Lady Stoneheart
Remember all those fans who were mad Catelyn Stark never came back from the dead on the show? Count Martin among their number. "Lady Stoneheart does have a role in the books," he tells EW. "Whether it's sufficient or interesting enough … I think it is, or I wouldn't have put her in. One of the things I wanted to show with her is that the death she suffered changes you." Though one GOT director has indicated the show's staff didn't quite know what to make of her, some fans are still holding out hope for her inclusion, even predicting that the title of the season-five finale is proof Stoneheart will make an appearance. If so, at least one bearded, bespectacled audience member will be cheering.