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General Opening Hours
Mon - Tue : 11am - 11pm
Wed - Thu : 11am - 12am
Fri - Sat : 10am - 1am
Sunday : 10am - 12am
The Sail and Anchor is an iconic Fremantle landmark. Come down and see just why this heritage listed pub is so appealing. With the spiraling staircase, wood paneled walls, pressed tin ceiling, and friendly staff, this venue is definitely worth booking for your next function.
Let's not forget the main attraction though. The beer. Boasting 40 cold taps, three hand pumps and four bars; it's no surprise that we are the leader of the craft beer revolution in Fremantle. The tap beer selection changes regularly, offering old classics, new favourites, small batch releases and seasonal styles, making a visit to the Sail and Anchor an adventure.
Functions - Meetings, cocktail Style weddings, engagements, birthdays & sundowners
Dining - Pub dining over the entire venue & garden cafe
Entertainment - Live music
64 South Terrace, FREMANTLE WA 6160
Ph 08 9431 1666


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Immersive Training Solutions (TS)
// How we help you
An effective training program imitates real-life conditions as closely as possible. A person who in real life situations might encounter heavy sensory experiences will have a reduced performance level unless having been trained in these environments.
// latest news
Can Olfactory Training Improve Your Sense of Smell?
The idea that you can improve your sense of smell might seem strange. Even the idea that different people have different strengths…Read More
Benefits of Multi-Sensory Training Solutions
Burning rubber, thick smoke, chemical vapors…these are just some of the extreme sensory experiences that military and first responders face. Inexperience dealing…Read More
SensoryCo Helps First Responders and Military Prepare with Military Olfactory Desensitization
First responders and military personnel are often in dangerous situations where they are assaulted by an ambush of sights, sounds, and smells…Read More

subset: commoncrawl


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You are here: Start Resources
|Game Studios
A list of game studios with examples of their work in the corporate environment and with serious games.
A checklist of what businesses should know when working with game studios.
|Gamification Platforms & Technologies
A matrix of gamification platforms and technologies for different niches with details and links, including paid and open source solutions.
A checklist for evaluating gamification platforms that help you decide which one to choose.
|A compilation of game and gamification design related books.


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|ognizant Communication Corporation
The Regenerative Medicine Journal
Cell Transplantation, Vol. 15, pp. 455-462, 2006
0963-6897/06 $90.00 + 00
Copyright © 2006 Cognizant Comm. Corp.
Printed in the USA. All rights reserved.
Myoblast Therapy: From Bench to Bedside
Zhongmin Liu,1 Yanling Wu,1 and Bing-guan Chen2
1Heart Center, Shanghai East Hospital, Tongji University,
Shanghai 200120, China
2Research Center, Shanghai East Hospital, Tongji University, Shanghai 200120, China
Myoblasts are defined as stem cells containing skeletal muscle cell precursors. A decade of experimental work has revealed many properties of myoblasts, including the stability of resulting hybrid myofibers without immune suppression, the persistence of transgene expression, and the lack of tumorigenicity. Early phase clinical trials also showed that myoblast-based therapy is a promising approach for many intractable clinical conditions, including both muscle-related and non-muscle-related diseases. The potential application of myoblast therapy may be in the treatment of genetic muscle diseases, cardiomyocyte damaged heart diseases, and urinary incontinence. This review will provide an overview of myoblast biology, along with discussion of the potential application in clinical medicine. In addition, problems in current myoblast therapy and possible future improvements will be addressed.
Key words: Myoblast therapy; Duchenne muscular dystrophy; Myocardiopathy; Incontinence; Gene therapy
Address correspondence to Bing-guan Chen, M.D., Ph.D., Medical Research Center, Shanghai East Hospital, Tongji University, 150 Jimo Rd, Shanghai 200120, China. Tel: +86-21-38804518; Fax: +86-21-58798999; E-mail: firstname.lastname@example.com
Cell Therapy for Parkinson's Disease: Only Young Onset Patients Allowed? Reflections About the Results of Recent Clinical Trials With Cell Therapy and the Progression of Parkinson's Disease
Gurutz Linazasoro
Centro de Investigación Parkinson (CIP), Policlínica Gipuzkoa, San Sebastián, Spain
The selection of the best candidates for surgery among Parkinson's disease (PD) patients is a debated topic. This could be particularly important for transplantation studies in which patients with advanced PD and motor complications refractory to conventional pharmacological treatments are usually included. The development of lesions in nondopaminergic structures, which apparently are unaffected by the intervention, could eventually lead to the appearance of disabling, treatment-resistant symptoms. This has been considered as the crucial factor responsible for the outcome of any therapeutic procedure. However, other factors might be involved. It is suggested in this article that the rate of progression of PD and the effects of ageing are more important than the extradopaminergic involvement in the final outcome. Rate of progression of PD is critically related to the power of compensatory mechanisms, which are age related and under the control of still unknown genes. Thus, patients with young onset parkinsonism (YOP), either caused by gene mutations or not, could be the best candidates for surgery because they have a slower disease progression and more competent compensatory mechanisms. On the other hand, this can also explain the appearance of unexpected side effects such as the "runaway" dyskinesias reported following transplantation.
Key words: Surgery; Transplantation; Parkinson's disease; Compensatory mechanisms; Neural plasticity
Address correspondence to Gurutz Linazasoro, Centro de Investigación Parkinson (CIP), Policlínica Gipuzkoa, Parque Tecnológico de Miramón, 20012 San Sebastián (Gipuzkoa), Spain. E-mail: firstname.lastname@example.com
Bridging Nigrostriatal Pathway With Fibroblast Growth Factor-Primed Peripheral Nerves and Fetal Ventral Mesencephalon Transplant Recuperates From Deficits in Parkinsonian Rats
Yung-Hsiao Chiang,1 Shinn-Zong Lin,2 and Feng C. Zhou3
1Department of Neurological Surgery, Tri-Service General
Hospital, National Defense Medical Center, Taipei, Taiwan
2Tzu-Chi General Hospital, Buddist Tzu-Chi University, Hua-Lien, Taiwan
3Department of Anatomy and Cell Biology, Paul Stark Neuroscience Institute, Indiana University School of Medicine, Indianapolis, IN, USA
Previous studies have indicated that the nigrostriatal dopaminergic (DA) pathway can be reconstructed in hemiparkinsonian rats with a bridge transplantation technique involving fetal ventral mesencephalic transplants and glial cell line-derived neurotrophic factor. In this study, we examined if the nigrostriatal pathway can be restored by combining peripheral nervous tissue with the fetal ventral mesencephalon transplants. Adult rats were injected with 6-hydroxydopamine into left median forebrain bundle. Those with marked rotational behavior, which has been previously shown to indicate complete DA dennervtion, were used for transplant treatments. One month after the lesion, fetal ventral mesencephalic cells were transplanted into the nigral region followed by nigral-striatal grafting of peripheral nerves as a bridge. The bridging nerves (sciatic or intercostals) were pretreated with basic fibrous growth factor (nerve+bFGF+) or Hank's saline (nerve+bFGF-). We found that (a) animals receiving transplants of VM and bFGF+ nerve had a reduction in rotational behavior; (b) animals receiving bFGF- nerve bridge only had a partial improvement in rotation. Reinnervation of tyrosine hydroxylase (TH)-immunoreactive (ir) fibers into the striatum was found in both of the above groups with more innervation in the former than in the latter. No TH-ir fibers in lesioned striatum or reduction in rotational behavior were found in animals receiving VM only, or VM plus bFGF. Taken together, our data indicate that peripheral nerve, with the aid of bFGF, greatly facilitates the reconstitution of the TH pathway from nigra to striatum and improves motor function in hemiparkinsonian rats.
Key words: Nigrostriatal pathway; Parkinsonian rats; Bridge transplantation; Peripheral nerves; Fetal ventral mesencephalon
Address correspondence to Yung Hsiao Chiang, M.D., Ph.D., Department of Neurological Surgery, Tri-Service General Hospital, National Defense Medical Center, 325 Cheng Kung Road, Sec. 2, Taipei, Taiwan. Tel: 886-2-87927177; E-mail: firstname.lastname@example.com
Inhibition of p38 MAP Kinase in the Early Posttransplantation Phase Redistributes Blood Vessels From the Surrounding Stroma Into the Transplanted Endocrine Tissue
Åsa Johansson,1 Daniel Sandvik,1 and Per-Ola Carlsson1,2
1Department of Medical Cell Biology, Uppsala University,
SE-751 23 Uppsala, Sweden
2Department of Medical Sciences, Uppsala University, SE-751 85 Uppsala, Sweden
Transplanted pancreatic islets attain a chronically decreased vascular density following transplantation, despite the increased concentrations of vascular endothelial growth factor (VEGF) secreted from beta-cells in response to hypoxia during culture and in the immediate posttransplantation phase. VEGF, however, exerts dual effects on endothelial cells, and in islet endothelial cells of the adult, the vascular permeability-inducing effects of VEGF seem normally more pronounced than those to induce angiogenesis. p38 MAP kinase activity has recently been shown to serve as a switch to separate these properties of VEGF; inhibition of p38 MAP kinase activity enhances VEGF-induced angiogenesis and, at the same time, abrogates VEGF-induced vascular permeability. We hypothesized that the revascularization of transplanted islets may be hampered by a predisposition of adult islet endothelial cells to react to VEGF by forming fenestrae rather than migrating and proliferating. We therefore administered the p38 MAP kinase inhibitor SB203580 by daily IP injections for the first 14 days following transplantation, and then studied the influence of this treatment on the oxygen tension, blood perfusion, and vascular density of the islet grafts 1 month posttransplantation. SB203580 treatment redistributed islet graft blood vessels from the stroma into the endocrine tissue, and this redistribution of blood vessels into the endocrine tissue was accompanied by an increased oxygenation of the islet cells. However, the total number of blood vessels in the tissue was not affected. The blood perfusion of the islet grafts was also similar in control and SB203580-treated animals. Our results suggest that effects of VEGF to preferentially induce vascular permeability may partially contribute to, but is not the main cause of, low revascularization of transplanted islets.
Key words: Engraftment; Bandeiraea simplicifolia; Blood flow; Oxygen tension
Address correspondence to Per-Ola Carlsson, M.D., Ph.D., Department of Medical Cell Biology, Uppsala University, Husargatan 3, Box 571, SE-751 23 Uppsala, Sweden. Tel: +46 18 471 4425; Fax: +46 18?471 40 59; E-mail: firstname.lastname@example.com
Isolated Pancreatic Islets in Three-Dimensional Matrices Are Responsive to Stimulators and Inhibitors of Angiogenesis
André Kidszun,1 Darius Schneider,1 Doris Erb,1 Gundula Hertl,1 Veronika Schmidt,2 Michael Eckhard,1 Klaus T. Preissner,2 Georg Breier,3 Reinhard G. Bretzel,1 and Thomas Linn1
1Medical Clinic and Policlinic 3, Justus Liebig University,
Rodthohl 6, 35392 Giessen, Germany
2Department of Biochemistry, Justus Liebig University, Friedrichstrasse 24, 35392 Giessen, Germany
3Department of Pathology, Medical Faculty Carl Gustav Carus, University of Technology Dresden, Fetscherstrasse 74, 01307 Dresden, Germany
The formation of a new microvasculature is essential for the long-term survival and function of the islet graft. In this study we examined endothelium of isolated pancreatic islets by stimulation with growth factors, different culture conditions, and genetic modification. We also inspected the effect of immunosuppressives used in human transplantation on angiogenesis. Isolated islets were embedded in a three-dimensional fibrin or Matrigel matrix. The effect of hyperglycemia, hypoxia, and the addition of VEGF and bFGF was investigated. We exposed islets from transgenic mice expressing the VEGF gene (RIP1VEGF-A) to high glucose (16.7 mmol/L) medium and tested the immunosuppressive agents rapamycin (100 ng/ml) and FK506 (100 ng/ml). To quantify angiogenesis the percentage of sprouting islets was determined. New endothelial capillary-like structures protruded from isolated pancreatic islets. Addition of VEGF to the islets and transgenic RIP-VEGF islets showed a two- to threefold increase of sprouting islets compared to control. Hypoxic culture conditions stimulated angiogenesis, resulting in a twofold increase of capillary sprouting. Rapamycin and FK506 proved to be potent inhibitors of angiogenesis in this system, because a decrease of sprouting islets of more than 20% by both agents was observed. Isolated pancreatic islets are capable of forming new capillary structures and are susceptible to pro- and antiangiogenic stimuli.
Key words: Angiogenesis; Islet transplantation; VEGF; Rapamycin; FK506; Fibrin matrix; Rip1VEGF-A
Address correspondence to Thomas Linn, M.D., Ph.D, Medical Clinic and Policlinic 3, Justus Liebig University, Rodthohl 6, 35392 Giessen, Germany. Tel: 0049-641-99-42841; Fax: 0049-641-99-42489; E-mail: firstname.lastname@example.com
Endothelial Cell Preservation at 10°C Minimizes Catalytic Iron, Oxidative Stress, and Cold-Induced Injury
Michael A. J. Zieger1,2 and Mahesh P. Gupta1
1Methodist Research Institute, Clarian Health Partners, Inc.,
Indianapolis, IN, USA
2Department of Medicine, Indiana University School of Medicine, Indianapolis, IN, USA
There is growing evidence that oxidative stress plays an important role in mediating the injury induced by hypothermia during the preservation of cells and tissues for clinical or research use. In cardiovascular allografts, endothelial cell loss or injury may lead to impaired control of vascular permeability and tone, thrombosis, and inflammation. We hypothesized that hypothermia-induced damage to the endothelium is linked to increases in intracellular catalytic iron pools and oxidative stress. In this study, bovine aortic endothelial cells and cell culture methods were used to model the response of the endothelium of cardiovascular tissues to hypothermia. Confluent cells were stored at 0°C to 25°C and cell damage was measured by lipid peroxidation (LPO) and lactate dehydrogenase release. Varying the bleomycin-detectible iron (BDI) in cells modulated cold-induced LPO and cell injury. In untreated cells, injury was highest at 0°C and a minimum at 10°C. A similar temperature-dependent trend was found in BDI levels and cell plating efficiencies. Arrhenius plots of cell killing and iron accumulation rates showed biphasic temperature dependence, with minima at 10°C and matching activation energies above and below 10°C. These findings imply that the mechanisms underlying the hypothermic increase in catalytic iron, oxidative stress, and cell killing are the same and that preservation of the endothelium may be optimized at temperatures above those routinely used.
Key words: Hypothermia; Oxidative stress; Iron; Endothelial cells
Address correspondence to Michael A. J. Zieger, Ph.D., Methodist Research Institute, Clarian Health Partners, Inc., 1701 North Senate Blvd., Indianapolis, IN 46202, USA. Tel: (317) 962-6940; Fax: (317) 962-9369; E-mail: email@example.com
Application of a New Subretinal Injection Device in the Dog
András M. Komáromy,1 Signe E. Varner,2 Eugene de Juan,3 Gregory M. Acland,4 and Gustavo D. Aguirre1
1School of Veterinary Medicine, University of Pennsylvania,
Philadelphia, PA 19104, USA
2SurModics, Inc., Irvine, CA 92606, USA
3Beckman Vision Center, University of California, San Francisco, CA 94143, USA
4Baker Institute, Cornell University, Ithaca, NY 14853, USA
The use of a new subretinal injection device (RetinaJectTM Subretinal Cannula, SurModics, Inc., Eden Prairie, MN) to access the subretinal space in the canine model was evaluated. Subretinal injections were performed in 33 mongrel dogs between 2 and 52 months of age (median = 9 months). In 5 normal dogs the injection of 150 μl saline or India ink occurred by using a conventional subretinal injection device (CSID) with a 30-gauge anterior chamber irrigating cannula. The sclera had to be surgically exposed and penetrated before the subretinal injection with the CSID could occur. After removing the CSID, the conjunctiva over the sclerotomy site had to be closed. In a second group of 28 dogs [16 normals, 10 RPE65 mutants, and 2 with progressive rod cone degeneration (prcd)], the 25-gauge needle of the RetinaJectTM was used to penetrate the conjunctiva and the sclera. Once the tip of the needle was close to the retinal surface, a 39-gauge polyimide cannula was extended and brought into apposition with the retina for the subsequent subretinal injection of 150 ml saline, India ink, or adeno-associated virus (AAV). No closure of the conjunctiva was required. The animals were clinically monitored between 1 and 59 weeks after surgery. From this second group 25 eyes were harvested for routine histological analysis either immediately after surgery or after a clinical observation time of between 1 and 40 weeks. Both devices provided equally successful access to the subretinal space. The main advantage of the RetinaJectTM was that no surgical dissection was required; this led to a shorter procedure time and milder postoperative conjunctival swelling. In summary, the use of the RetinaJectTM can be recommended as an alternative to the CSID for subretinal injections in dogs.
Key words: Animal model; Dog; Retinitis pigmentosa; Subretinal injection
Address correspondence to András M. Komáromy, D.M.V., Ph.D., Department of Clinical Studies, School of Veterinary Medicine, University of Pennsylvania, 3900 Delancey Street, Philadelphia, PA 19104, USA. Tel: 215-573-2695; Fax: 215-573-2162; E-mail: firstname.lastname@example.com
Periosteal Cell Pellet Culture System: A New Technique for Bone Engineering
Maril Akiyama,1,2 Hidehiko Nonomura,1 Syed H. Kamil,1 and Ronald A. Ignotz1
1Center for Tissue Engineering, University of Massachusetts
Medical School, Worcester, MA 01655, USA
2Department of Biomaterials, Osaka Dental University, Hirakata-shi, Osaka 573-1121, Japan
To treat bone loss that is induced by disease or wounds, bone grafts are commonly used. In dentistry, guided tissue regeneration is effective in the treatment of periodontal diseases. However, bone resorption after implantation is a major problem with the bone graft and guided tissue regeneration technique. This study examines a cell pellet culture system without exogenous scaffolds for bone regeneration. First, we examined the effect of ascorbic acid on cells. Transmission electron microscopic observation revealed that cells formed a three-dimensional structure of multiple cell layers after 5 weeks of culturing in medium containing 50 mg/ml ascorbic acid with the medium changed every 7 days. A single cell pellet was produced by centrifuging cells that were gathered from 10 tissue culture dishes. Van Gieson staining and collagen type I immunostaining showed that the pellet contained collagen fibers and cells that adhered to the collagen fibers. Several of these cell pellets were implanted subcutaneously on the backs of nude mice for 6 weeks. Histology and immunohistochemistry results indicated new bone formation, vascular invasion, and insular areas of calcification. Bone tissue was surrounded by osteoblasts. The appearance of new bone formation is similar to that seen in intramembranous ossification. The present pellet system is reliable and might solve problems of bone resorption after implantation.
Key words: Pellet culture system; Bovine periosteal cells; Bone regeneration; Three-dimensional structure
Address correspondence to Mari Akiyama, Department of Biomaterials, Osaka Dental University, Hirakata-shi, Osaka 573-1121, Japan Tel: +81-72-864-3056; Fax: +81-72-864-3156; E-mail: email@example.com
Directed Three-Dimensional Growth of Microvascular Cells and Isolated Microvessel Fragments
Carlos C. Chang1 and James B. Hoying1,2,3
1Biomedical Engineering Program, University of Arizona, Tucson,
2Arizona Research Laboratories, University of Arizona, Tucson, AZ 85724, USA
3The BIO5 Institute, University of Arizona, Tucson, AZ 85724, USA
Tissue engineering has promise as a means for repairing diseased and damaged tissues. A significant challenge in tissue construction relates to the constraints placed on tissue geometries resulting from diffusion limitations. An ability to incorporate a premade vasculature would overcome these difficulties and promote construct viability once implanted. Most in vitro microvascular fabrication strategies rely on surface-associated cell growth, manipulated cell monolayers, or random arrangement of cells within matrix materials. In contrast, we successfully suspended microvascular cells and isolated microvessel fragments within collagen and then microfluidically drove the mixtures into microfabricated network topologies. Developing within the 3D collagen matrix, patterned cells progressed into cord-like morphologies. These geometries were directed by the surrounding elastomer mold. With similar techniques, suspended fragments formed endothelial sprouts. By avoiding the addition of exogenous growth factors, we allowed constituent cells and fragments to autonomously develop within the constructs, providing a more physiologically relevant system for in vitro microvascular development. In addition, we present the first examples of directed endothelial cell sprouting from parent microvessel fragments. We believe this system may serve as a foundation for future in vivo fabrication of microvascular networks for tissue engineering applications.
Key words: Microvascular; Tissue engineering; Microcirculation; Cell patterning
Address correspondence to James B. Hoying, University of Arizona, UA PO Box 245084, Tucson, AZ 85724-0001, USA. Tel: 520-626-5273; Fax: 520-626-2890; E-mail: firstname.lastname@example.com


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Watch Teen Wolf Season 1 Episode 10 online via TV Fanatic with over 6 options to watch the Teen Wolf S1E10 full episode. Affiliates with free and paid streaming include Amazon, iTunes, Vudu, YouTube Purchase, Google Play, and Amazon Prime.
|Watch Now
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|Watch Now
|YouTube Purchase
|Watch Now
|Google Play
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|Amazon Prime
|Watch Now
Episode Details
Stiles learns something about Derek's family. Elsewhere, Scott does all he can to protect his friends from the Alphas.
- Show:
- Teen Wolf
- Season:
- Teen Wolf Season 1
- Episode Number:
- 10


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Control how many times a user can see your AD (to avoid overexposure)
Users can get sick and tired of being 'followed' online by your ads. I like to set my bid high, but at the same time prefer that users only see the ad max X times per day/week, for instance.
57 votes
Geert shared this idea


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The latest British high-tech aeronautical achievement
Is Geneva airport ready to authorise the landing of paper aeroplanes piloted by a Playmobil figure? At Madrid, they were ready, tracking the descent as well as possible despite the difficulties!
13:11 Posted in Potpourri | Permalink | Comments (0) | Tags: playmobil, vulture, paper, plane | | del.icio.us | | Digg | Facebook


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Big Thinkers Giving Back
Were we are today is because of people and opportunities that have presented themselves into our lives. With that thought in mind each of our Big Thinkers wants to show it's gratitude for those along their professional and personal journeys who have positively impacted their lives. They are doing so by donating a portion of all client business to alternating charities. There is so much need in the world that Big Thinkers isn't looking to make a difference with just one, but with as many as they can.
Together we can make a difference.


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Some frank words about Overdrive and the mess that is DRM:
The point of libraries is to make content freely available for the common good, I thought, so these restrictions are a little weird. Physical library cards don't require a certain type of wallet; why should the electronic ones only work on Windows? I asked Chris Pasco-Pranger, a "willfully unemployed librarian" (his words), to explain the system, and he had some choice words for the OverDrive system.
Here's how he responded (edited for clarity and length):
"Any patron of a member library can download titles (eBooks, audio, etc.) available from Overdrive to a home PC for a specified loan period. Typically, one approaches the service through a Public Library's website, for example at Brooklyn Public Library –> eBooks, eVideo & eAudio in the left navbar –> Search the Digital Media Catalog. You can add titles to a cart and then checkout using your library card number. A DRM scheme is applied, so you can only play a given title during the lending period, you can't burn it to disc, etc.
"The biggest problem (by far) with Overdrive ('Our strategic technology partners include Microsoft Corporation, Adobe Systems, Inc., and Mobipocket.') is its lack of support for Macs/iPods. Read the FAQ and weep. Of course, Overdrive would say that it's Apple that doesn't support THEM, because, y'know, Overdrive is SO much bigger of a deal than the iPod. Oh, the DRM headaches…


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Details about this Driver
|Download driver for: SONY VGN-BZ569P
|Supported System
|Win 7, Win 10, Win XP, Win 8, Win Vista, Win 8.1, Win Server 2003
|File Size
|7938 kb
|VAIO Care Software Update for SONY VGN-BZ569P
This utility updates the VAIO Care software to version6.3.0.09020 and provides the following benefits:
Updates the support phone number listed for Brazil within the VAIOCare software
Improves the Self Heal functionality by allowing critical updatesto be installed silently
Improves the VAIO Care user interface
Provides a link to the Sony® forum within the Contact Sonyoption
Improves the performance of the VAIO Care application
The Safest Way to Update Sony Drivers
Way to Update Drivers with Device Manager
QUESTION: I have Sony Vaio STV151A11D laptop keybord its not functioning , I been make reserch site for discover the option , but I cant obtain any answer. I living in france , and it doesnt have any a lot more sony vaio assistance .. Thank you and seeking foward hear from you soon .
ANSWER: Sorry to hear about this. Ensure that there are no debris on the keyboard and no water spill. Reinstall the keyboard driver from Device Manager. Reset BIOS to default setting. You could possibly also wish to perform method restore back to an earlier date when the keyboard was nevertheless working. You could possibly also run DriverTuner to download the Sony drivers and Windows Update for Microsoft drivers.
To update driver for SONY VGN-BZ569P using Windows Update.
You can check Windows Update any time to see if it's found updated drivers for your devices, especially if you recently installed a new device. Then, you can install the updated drivers. Here's how:
- Open Windows Update by clicking the Start button. In the search box, type Update, and then, in the list of results, click Windows Update.
- In the left pane, click Check for updates. If there are any available updates, click the links to see more information about each update. Windows Update tells you if an update is important, recommended, or optional. Each type of update might include drivers for SONY VGN-BZ569P.
- On the Select the updates you want to install page, look for updates for your SONY VGN-BZ569P, select the check box for each driver that you want to install, and then click OK. There might not be any available driver updates.
- On the Windows Update page, click Install updates. If you're prompted for an administrator password or confirmation, type the password or provide confirmation. Windows Update will tell you if the updates were successfully installed.
Still can't Fix SONY VGN-BZ569P Driver Problem? Don't Worry! You can Try DriverTuner
1. Download DriverTuner and install it
2. Scan your computer for outdated drivers. Select the ones(here you should choose SONY VGN-BZ569P) you want to update and click download
3. After the download process is finished, you should click SETUP to install them. That's it! Your driver for SONY VGN-BZ569P has been updated. Sometimes a reboot is required to let the drivers take effect.
|Fix Driver Problems
|Driver Update Tool
Windows 10, 8, 7, Vista and XP


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Home › Forums › Discussion by State › Kentucky › Kentucky Concealed Carry Permits
Tagged: ccw, concealed carry, kentucky, license, permit
This topic contains 0 replies, has 1 voice, and was last updated by Jacob Paulsen 1 year, 11 months ago.
- AuthorPosts
- August 24, 2016 at 9:58 am #77994
Jacob PaulsenParticipant
May Issue VS Shall Issue: Shall Issue to Residents Only
Issuing Authority: Kentucky State Police
Required Training: A certificate or an affidavit or document certifying completion of a firearms training course offered or approved by the Department of Criminal Justice Training.
How to Apply: The application will be sent to the Kentucky State Police within five working days. The Department of Kentucky State Police shall, within 90 days, either issue a license or deny the application, in which case the applicant shall be informed in writing of the grounds for denial and his right to submit, within 30 days, documentation relating to the denial.
Non-Residents: No, Kentucky will only issue a License to Carry to military personnel if: Is a citizen of the United States who is a member of the Armed Forces of the United States who is on active duty, who is at the time of application assigned to a military posting in Kentucky (If you meet the above requirement you would apply like a resident.)
Renewal: Permits are valid for five years before renewal. If you fail to renew your license on or before the expiration date and wish to renew your license, you will be required to pay an additional late fee of fifteen dollars ($15.00). If six months or more has passed since the expiration date of your license, your license has permanently expired and cannot be renewed. If your license has permanently expired, you may reapply for licensure pursuant to KRS 237.110 by obtaining a CCDW application from the Sheriff of your county of residence.
Processing Time: within 90 days
Cost: The applicant must pay the $60 application fee at the time of application.
Change of Address:You are required to notify the Kentucky State Police within thirty days after the changing of your permanent address or other information on your license. Failure to do so is a noncriminal violation with a penalty of twenty-five dollars payable to the clerk of the District Court. To change or update your address or personal information, you must complete a Carry Concealed Deadly Weapons Licensee Request for Change of Personal Information (KSP 121) form at the office of the Sheriff of your county of residence. Once completed, the Sheriff will forward the information to the Kentucky State Police.
Required to Notify Law Enforcement: No
Places Off Limits When Carrying:
Federal restrictions include all Federal Building, National monuments, National memorials, secure areas.
State Restrictions include:
- Police station or sheriff's office.
- Detention facility, prison or jail.
- Courthouse (Court of Justice, courtroom or court proceeding).
- County, municipal, or special district governing body meetings.
- Meeting of governing body of a county, municipality, or special district.
- General Assembly session, including committee meetings.
- Any portion of an establishment licensed to dispense beer or alcoholic beverages for consumption on the premises, which portion of the establishment is primarily devoted to that purpose.
- Elementary or secondary school facilities (without the consent of school authorities).
- Child-caring facilities, day care centers, or any certified family child care home.
- Areas within an airport where restricted access is controlled by the inspection of persons or property.
- Any place where federal law prohibits the carrying of a firearm.
In addition to the above restrictions, units of state and local governments and postsecondary education facilities (colleges, universities, technical schools and community colleges) have the authority to limit the carrying of concealed weapons on property owned or controlled by them (KRS 237.115). You should check with units of state and local government as well as postsecondary education facilities prior to carrying a concealed weapon on their property.
Private Property Prohibitions:"Handgunlaw.us highly recommends that you not enter a place that is posted "No Firearms" no matter what the state laws read/mean on signage. We recommend you print out the No Guns = No Money Cards and give one to the owner of the establishment that has the signage." As responsible gun owners and upholders of the 2nd Amendment we should also honor the rights of property owners to control their own property even if we disagree with them." "No Firearm" signs in Kentucky have no force of law unless they are posted on property that is specifically mentioned in State Law as being off limits to those with a Permit/License to Carry. If you are in a place not specifically mentioned in the law that is posted and they ask you to leave, you must leave. If you refuse to leave then you are breaking the law and can be charged. Even if the property is not posted and you are asked to leave you must leave. Always be aware of the possibility that responding Police Officers who may have been called without your knowledge and may not know the laws on trespass etc. could arrest you even if you are within the law.
State Website: Kentucky
Current Reciprocity Map:
- AuthorPosts
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Child Nutrition Billing and Collections
2017 Special Education Graduate Survey
1st day of school- 8-22-18
Order transcripts here!
Click on your school to go to the order page:
Check out these highlights from Pleasant Valley Elementary School
Professional Personnel Sub Callout
Welcome to Marion County Schools Web Page! We are proud to offer high quality education to the youth in our county. As you look at County Schools you will see a progressive attitude with a focus on education and using technology to enhance that focus. We are excited that you have decided to join us on this Web Page. The page was designed with you as a patron in mind. As you review these sites please feel free to comment on how we can improve our information for the community. We are excited that you will take part in helping us prepare the future of our community. My office is located at 1516 Mary Lou Retton Drive in Fairmont. (Appointments suggested by calling 304-367-2100).
You can also contact me by email at email@example.com. Thank you once more for visiting our website.


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BENTON, Ill. -- The driver of a Greyhound bus that struck and killed a southern Illinois firefighter will serve 2 years of probation and pay $2,000 in fines as part of a plea deal with prosecutors.
Sammie Rogers Jr., 42, of Chicago was sentenced Wednesday on charges of misdemeanor reckless driving after entering a plea in which he didn't admit guilt but acknowledged prosecutors had sufficient evidence for a conviction.
Franklin County prosecutors dropped a reckless homicide count.
Authorities say Rogers' northbound bus hit volunteer Sesser firefighter James "Shib" Miller on Interstate Highway 57 in July 2007. Illinois State Police said the 43-year-old Miller had just helped douse a tractor-trailer blaze along the freeway and was helping to clear the scene when the bus traveled through traffic cones, hit the left rear side of a Sesser fire truck, then struck Miller.


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Save the Children Liberian Nurse Visit
06/03/2012. OXFORD, UK. Liberian nurses Watta Mamie Borbor (pictured right) and Rommina Yah (pictured centre right) visit the children's wing of John Radcliffe Hospital in Oxford on behalf of charity Save the Children. Matron Nettie Dearmun (pictured left) gave them a guided tour before they met nurse Charlie McCulloch (pictured centre left) who spent time with them in Liberia. Photo credit: Cliff HideAdd to Lightbox Download


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My name is Beth Whitaker. I am a group fitness Instructor at the Keller location. I teach HIIT at 6:30PM On Mondays
On this Journey my goals are to make the best of our workouts, keep them challenging all while having fun! I started my love for fitness in High School and love the physical and emotional challenges we face when exercising. For me, exercise was all mental therapy since I have ADHD, starting my day with a good workout gives me my sanity. I was a special ed teacher for 12 years, and have always had a passion for helping others and celebrating with them through their successes, large or small. Fitness is also where I have met the best of friends through events that I had participated in: half-marathons, one full marathon, triathlons, strength training, soccer, softball, etc.
Through all of this, I learned the most effective ways to stay in shape, how important it is to continually educate yourself on new and innovative workouts, working out as a group seems so much more effective in so many ways.


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Council likely to vote Tuesday on opening Park Avenue
By Ty Johnson
Published in News on July 3, 2011 1:50 AM
When the City Council meets Tuesday night for the first time in the 2011-12 fiscal year, it will make decisions on many items it considered for much of 2010-11.
A decision is expected concerning the council's next step toward opening Park Avenue through Herman Park more than two months after the council voted to remove the bollards that were erected in late 2010, closing the street without properly allowing the public to speak out on it.
A measure to reduce the speed limit of the section of the road that runs through Herman Park from 25 to 10 mph is on the consent agenda, along with site and landscape plans for a proposed Social Security administration building and a museum building requested by the Old Waynesborough Commission.
The council's consent agenda also contains a resolution requesting the North Carolina Department of Transportation to name the new U.S. Highway 70 Bypass over Wayne Memorial Drive after Goldsboro's four police officers who died on duty.
The sole public hearing of the meeting will be on the city's delaying and rescheduling of the 2011 municipal election. The redistricting maps, necessary because of population shifts revealed by last year's Census data, must be approved by the Department of Justice because of Wayne County's situation concerning the Voting Rights Act of 1965. To maintain the act's requirement of "one person, one vote," elections cannot be held until the districts are set, but a hearing must be held before a delay can be approved.
Other items the council will discuss include the approval of the redistricting of electoral districts, the demolition of the Golds Inn on Highway 70 East near Highway 117, the renovation of hole 14 at the city's municipal golf course and a budget amendment authorizing the Finance Department to purchase the building at 2406 E. Ash St. from the Arts Council of Wayne County. Discussions about the building have proposed locating an Air Force museum at the location.


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The Digital Cartographic Standard for Geologic Map Symbolization, FGDC-STD-013-2006, was published and released as a print document in October, 2008. Available online in PDF format since August, 2006, a printed version was found to be a useful supplement because of the standard's length and the complexity and high resolution of many symbols.
The Digital Cartographic Standard for Geologic Map Symbolization provides the Nation's producers and users of geologic map information a single modern standard for the digital cartographic representation of geologic features. Use of this standard will give maps and related products a consistent appearance. The standard provides descriptions, examples, cartographic specifications, and notes on usage for a wide variety of symbols that might be used on a digital geologic map or related product (for example, cross sections). It includes a CMYK color chart, a chart of commonly used geologic map patterns, a geologic age symbol font, bar scales, mean declination arrows, and quadrangle location maps.
The standard is designed for producers and users digital geologic map information. It applies to geologic map information published by the Federal government in both offset-print and plot-on-demand formats. It is also suitable for electronic publications (for example, in a Portable Document Format (PDF) file) and display on computer monitors. The standard is scale-independent, meaning that the symbols are appropriate for geologic maps at any scale. Non-Federal agencies and private companies that produce geologic-map information are urged to adopt this standard as well.
In addition to the print publication, the Digital Cartographic Standard for Geologic Map Symbolization is also available in the following formats:
1. PDF format, which is best for viewing and plotting
2. PostScript format, for use in Adobe Illustrator and other graphic-design software
3. An ESRI version is under development. A beta version is
anticipated for testing in Spring, 2009
FGDC Geologic Data Subcommittee sponsored development of the
Digital Cartographic Standard for Geologic Map Symbolization. The
FGDC endorsed the standard in August 2006.
The USGS maintains the Digital Cartographic Standard for Geologic Map Symbolization. Office of Management and Budget (OMB) Circular A-16 designates the USGS as the lead agency for geologic data. The Geologic Mapping Act of 1992 (and subsequent reauthorizations) stipulates standards development under the auspices of the National Geologic Map Database (NGMDB). Under this authority, the NGMDB will function on behalf of the USGS as coordinator of this maintenance activity (see http://ngmdb.usgs.gov/info/standards/). Maintenance will be conducted in cooperation primarily with the Association of American State Geologists (AASG), which is the USGS's partner in the Geologic Mapping Act.
The Map Symbol Committee provides technical advice to preparers of the Digital Cartographic Standard for Geologic Map Symbolization. Committee membership comes from the NGMDB, USGS scientific staff and Publications Groups, the AASG, and the academic community. The NGMDB relies on the Map Symbol Committee to help maintain the Standard. The Map Symbol Committee will review comments and suggestions for revisions, additions, and deletions to the standard. A log of revisions to each section of the Standard is maintained.
Users and producers are invited to submit comments and suggestions for updates or other improvements to the Digital Cartographic Standard for Geologic Map Symbolization by email to: mapsymbol [at] flagmail.wr.usgs.gov.
For more information about the Digital Cartographic Standard for Geologic Map Symbolization, please contact David Soller (drsoller [at] usgs.gov) at (703) 648-6907.


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Our Boys Team Program follows the guidelines established by the national gymnastics governing body (USA Gymnastics). The program starts every athlete with a strong foundation. This foundation involves: strength, flexibility, and essential key elements/skills in order to develop a strong competitive gymnast for future years.
Summer: (Mid June - Late August)
Fall: (September - Late December)
Winter: (January - April)
Spring: (May - Early June)
Compulsory Level 4
Compulsory Level 5
Compulsory Level 6
Compulsory Level 7
Optional Level 8
Optional Level 9
Optional Level 10
Our Level 4 Boys Team took 1st Place at the 2016 MN State Championships - 2 years in a row!
For the first time in Maple Grove GGS history, our Level 5 Boys won the 2016 Minnesota Boys State Championships!


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(121)Northwoods Living at Its Finest! Discover the advantages of Up-North living in this custom 1 1/2 story home with architectural dormers situated on 43+/- acres of mature hardwoods and fields offering privacy and abundant wildlife. The striking design features 3-4 bedrooms, 2 baths, a deck and large, open porch. The well-landscaped lawn has mulberry and apple trees, plus an assortment of other varieties. All appliances included in sale. Enjoy what some people only dream of. Located on Fairview Road northwest of Kennan. Serious inquiries only. Additional 40 acres available. (5-35-2W)
Features Residential
|Style: 1.5 Story
|Lake Chain:
|Garage: 2 Car, Attached, Detached, Multiple Garages
|Lake Name:
|Year Built: 1978
|River Name:
|Basement Type: Full Basement, Interior Entrance, Laundry Hookups
|Water Frontage (feet): 0
|Fin SqFt Total: 1,865
|Lake Size-Acres: 0
|Lot Size: 1873080
|High School: PR Phillips
|Site Influence: Driveway, Easy Access, Hunting, Park Setting, Pasture Land, Private Setting, Rural Setting, Stream/Creek, Wooded Area
|School District: Phillips
|Construction: Frame/Stick


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From Dallas, Pennsylvania, USA:
My 12 year old daughter has had type 1 diabetes since she was 10. How long does it take for full type 1 diabetes to surface in a child? Is it a long process or can it happen overnight?
The destruction of the beta cells in the pancreatic islets by autoimmunity usually takes a number of years. In its later stages, however, the final development of clinical or insulin dependent diabetes may take place very suddenly often as the result of some intercurrent infection.
Original posting 26 Jun 2002
Posted to Diagnosis and Symptoms
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Last Updated: Tuesday April 06, 2010 15:09:34
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text: 23 May 2013If you�re over 40 and have finally decided to take the plunge and undergo a cosmetic procedure, you might be thinking about getting Botox or fillers. Traditionally injected around the eyes and forehead, these help diminish the appearance of lines and wrinkles caused by every day movement. Elsewhere they can help change things like a downturned mouth.Permanent hair reduction is another option for those in their 40s. Approved laser procedures for both men and women can deliver hair loss exactly where they want it. Liposuction can reduce fat all over the body and the destruction of fat cells can be in the form of high negative pressure, ultrasonic or laser energy and mechanical energy. Laser-assisted liposuction destroys fat cells and is best used on small, localised areas. The liquefied remains of fat stay in the body for three to six weeks until they are absorbed. Often in cases where more fat needs to be removed, power assisted liposuction is used. Over 40s can often be the victim of droopy eyelids. If this is a problem, surgery might be an option to rid the face of its bags.