text:
House of Lords Journal 236 (Session 2002-03)
Lords Journals
Minutes and Order Papers
Monday 2 December 2002
The House met at half-past two oclock.
The following Lords Spiritual and Temporal were present:
Irvine of Lairg, L.
Page 49
Fearn, L.
Ferrers, E.
Filkin, L.
Fitt, L.
Flather, B.
Fookes, B.
Fowler, L.
Freyberg, L.
Gale, B.
Gardner of Parkes, B.
Garel-Jones, L.
Geddes, L.
Geraint, L.
Gibson of Market Rasen, B.
Gladwin of Clee, L.
Golding, B.
Gordon of Strathblane, L.
Goudie, B.
Graham of Edmonton, L.
Gray of Contin, L.
Greengross, B.
Greenway, L.
Griffiths of Fforestfach, L.
Grocott, L.
Hanham, B.
Hanningfield, L.
Hardy of Wath, L.
Harris of Haringey, L.
Harris of Richmond, B.
Haskel, L.
Haskins, L.
Hayhoe, L.
Hayman, B.
Henley, L.
Higgins, L.
Hodgson of Astley Abbotts, L.
Hogg of Cumbernauld, L.
Holme of Cheltenham, L.
Hooper, B.
Hooson, L.
Hope of Craighead, L.
Howe, E.
Howe of Aberavon, L.
Howe of Idlicote, B.
Howell of Guildford, L.
Howells of St. Davids, B.
Hughes of Woodside, L.
Hunt of Chesterton, L.
Hunt of Wirral, L.
Hussey of North Bradley, L.
Hylton, L.
Inge, L.
Inglewood, L.
Islwyn, L.
Jacobs, L.
Janner of Braunstone, L.
Jauncey of Tullichettle, L.
Jeger, B.
Jenkin of Roding, L.
Jones, L.
Jordan, L.
Kimball, L.
King of Bridgwater, L.
King of West Bromwich, L.
Laird, L.
Lamont of Lerwick, L.
Lea of Crondall, L.
Lester of Herne Hill, L.
Lipsey, L.
Lloyd of Berwick, L.
Lofthouse of Pontefract, L.
Lucas, L.
Luke, L.
Lyell, L.
McColl of Dulwich, L.
MacGregor of Pulham Market, L.
McIntosh of Haringey, L.
MacKenzie of Culkein, L.
Mackenzie of Framwellgate, L.
Maclennan of Rogart, L.
McNally, L.
Maddock, B.
Mallalieu, B.
Mancroft, L.
Marsh, L.
Masham of Ilton, B.
Mason of Barnsley, L.
Massey of Darwen, B.
Mayhew of Twysden, L.
Merlyn-Rees, L.
Michie of Gallanach, B.
Miller of Hendon, B.
Milner of Leeds, L.
Mishcon, L.
Molyneaux of Killead, L.
Monro of Langholm, L.
Monson, L.
Montagu of Beaulieu, L.
Moran, L.
Morgan, L.
Morris of Manchester, L.
Mowbray and Stourton, L.
Moynihan, L.
Murton of Lindisfarne, L.
Naseby, L.
Newby, L.
Newton of Braintree, L.
Noakes, B.
Northbourne, L.
Northbrook, L.
Northesk, E.
Northover, B.
OCathain, B.
Onslow, E.
Oppenheim-Barnes, B.
Orme, L.
Ouseley, L.
Owen, L.
Oxburgh, L.
Oxford, Bp.
Palmer, L.
Parekh, L.
Park of Monmouth, B.
Patel, L.
Patel of Blackburn, L.
Paul, L.
Pearson of Rannoch, L.
Pendry, L.
Perry of Southwark, B.
Perry of Walton, L.
Peston, L.
Peyton of Yeovil, L.
Phillips of Sudbury, L.
Pilkington of Oxenford, L.
Pitkeathley, B.
Plant of Highfield, L.
Plumb, L.
Ponsonby of Shulbrede, L.
Prior, L.
Prys-Davies, L.
Quirk, L.
Radice, L.
Ramsay of Cartvale, B.
Randall of St. Budeaux, L.
Rawlings, B.
Razzall, L.
Rea, L.
Redesdale, L.
Rees, L.
Rees-Mogg, L.
Rendell of Babergh, B.
Rennard, L.
Renton, L.
Richard, L.
Rix, L.
Roberts of Conwy, L.
Rodgers of Quarry Bank, L.
Rogan, L.
Roll of Ipsden, L.
Roper, L.
Russell, E.
Saatchi, L.
Sainsbury of Turville, L.
St. John of Bletso, L.
St. John of Fawsley, L.
Saltoun of Abernethy, Ly.
Sandberg, L.
Sawyer, L.
Scotland of Asthal, B.
Scott of Needham Market, B.
Seccombe, B.
Sharp of Guildford, B.
Sharples, B.
Shaw of Northstead, L.
Sheldon, L.
Shrewsbury, E.
Shutt of Greetland, L.
Simon, V.
Simon of Glaisdale, L.
Skelmersdale, L.
Skidelsky, L.
Slim, V.
Smith of Clifton, L.
Smith of Gilmorehill, B.
Soulsby of Swaffham Prior, L.
Southwark, Bp.
Stern, B.
Stevens of Ludgate, L.
Stewartby, L.
Stoddart of Swindon, L.
Stone of Blackheath, L.
Strabolgi, L.
Strange, B.
Strathclyde, L.
Swinfen, L.
Taverne, L.
Taylor of Blackburn, L.
Tebbit, L.
Temple-Morris, L.
Tenby, V.
Thomas of Gresford, L.
Thomas of Macclesfield, L.
Thomas of Swynnerton, L.
Thomas of Walliswood, B.
Thomson of Monifieth, L.
Thornton, B.
Tordoff, L.
Trumpington, B.
Turnberg, L.
Turner of Camden, B.
Uddin, B.
Varley, L.
Waddington, L.
Wade of Chorlton, L.
Wakeham, L.
Walker of Doncaster, L.
Walmsley, B.
Warner, L.
Warnock, B.
Warwick of Undercliffe, B.
Whitaker, B.
Whitty, L.
Wigoder, L.
Wilberforce, L.
Wilcox, B.
Wilkins, B.
Williams of Crosby, B.
Williams of Elvel, L.
Williams of Mostyn, L.
Williamson of Horton, L.
Worcester, Bp.
Wright of Richmond, L.
PRAYERS were read by the Lord Bishop of Chelmsford.
Judicial Business
|Grobbelaar (Appellant) v. News Group Newspapers Limited and another (Respondents)Further to the Judgment of the House of 24th October last (69th Report from the Appellate Committee (Session 2001-02) [2002] UKHL 40), it was ordered that paragraph 2 of the Order of Mr Justice Gray of 28th July 1999 be set aside; save that the interim orders made in the course of the proceedings stand, that the appellant do pay to the respondents two-thirds of the cost of the trial before Mr Justice Gray, in the Court of Appeal and before this House, the amount of such last-mentioned costs to be certified by the Clerk of the Parliaments if not agreed between the parties.
|Regina v. H M Coroner for the Western District of Somerset (Respondent) and another (Appellant) ex parte Middleton (FC) (Respondent) (England)The appeal of the Secretary of State for the Home Department was presented and it was ordered that in accordance with Standing Order VI the statement and appendix thereto be lodged on or before 13th January next (lodged 28th November).
|Chester (Respondent) v. Afshar (Appellant) (England)The appeal of Fari Afshar was presented and it was ordered that in accordance with Standing Order VI the statement and appendix thereto be lodged on or before 13th January next.
|Jackson and another (Petitioners) v. Royal Bank of Scotland (Respondents)The petition of James Jackson and Chui-Mang Davies praying for leave to present an appeal notwithstanding that the time limited by Standing Order I has expired was presented and referred to an Appeal Committee.
|Anheuser-Busch Inc (Petitioners) v. Budejovicky Budvar Narodni Podnik (Respondents)The petition of Anheuser-Busch Inc praying for leave to appeal was presented and referred to an Appeal Committee (lodged 29th November).
|Regina v. Monmouthshire County Council (Respondents) ex parte M W H & H Ward Estates Limited (Petitioners)The petition of M W H & H Ward Estates Limited praying for leave to appeal was presented and referred to an Appeal Committee.
|Matthews (Appellant) v. Ministry of Defence (Respondents)The appeal was set down for hearing and referred to an Appellate Committee.
|Tomlinson (Original Respondent and Cross-appellant) v. Congleton Borough Council and others (Original Appellants and Cross-respondents)The petition of the original appellants praying that the time for lodging the statement and appendix and setting down the cause for hearing might be extended to 7th January next (the agents for the original respondent consenting thereto) was presented; and it was ordered as prayed.
|Command PapersThe following papers, having been presented to the House by command of Her Majesty on the dates shown, were ordered to lie on the Table:
|ImmigrationControl of Immigration: National Statistics for 2001; (29th November)
|Commercial DebtsExchange of Notes between the United Kingdom and Cote dIvoire regarding Certain Commercial Debts; (29th November)
|Departmental PerformanceAutumn Performance Reports 2002 of the
|Export Credits Guarantee Department; (29th November)
|Department for Education and Skills; (29th November)
|Office of the Deputy Prime Minister; (29th November)
|Department for International Development; (29th November)
|Museums and GalleriesReport and Accounts for 200102 of the Greater Manchester Museum of Science and Industry Trust.
|Statutory Instruments (Standing Order 71)The following negative instruments, having been laid before the House on 29th November, were laid before the House and ordered to lie on the Table:
|M11 Motorway (Junction 8) (Speed Limit) Regulations 2002, laid under the Road Traffic Regulation Act 1984;
|Community Design (Fees) Regulations 2002, laid under the Finance Act 1973;
|Negative InstrumentsThe following instruments were laid before the House and ordered to lie on the Table:
|Reciprocal Enforcement of Maintenance Orders (Hague Convention Countries) (Variation) Order 2002, laid under the Maintenance Orders (Reciprocal Enforcement) Act 1972;
|2. (i)
|Architects Qualifications (EC Recognition) Order 2002
|European Communities (Designation) (No. 4) Order 2002
|laid under the European Communities Act 1972;
|Criminal Justice Act 1988 (Designated Countries and Territories) (Amendment) (No. 2) Order 2002, laid under the Criminal Justice Act 1988;
|Criminal Justice (International Co-operation) Act 1990 (Enforcement of Overseas Forfeiture Orders) (Amendment) (No. 2) Order 2002, laid under the Criminal Justice (International Cooperation) Act 1990;
|Drug Trafficking Act 1994 (Designated Countries and Territories) (Amendment) (No. 2) Order 2002, laid under the Drug Trafficking Act 1994;
|Education Act 2002 (Modification of Provisions) (No. 2) (England) Regulations 2002, laid under the Education Act 2002;
|7. (i)
|Education (Determination of Admission Arrangements) (Amendment) (England) Regulations 2002
|Education (School Information) (England) Regulations 2002
|Education (Variation of Admission Arrangements) (England) Regulations 2002
|Education (Admissions Appeals Arrangements) (England) Regulations 2002
|Education (Admission Forums) (England) Regulations 2002
|Education (Objection to Admission Arrangements) (Amendment) (England) Regulations 2002
|Education (Coordination of Admission Arrangements) (Primary Schools) (England) Regulations 2002
|Education (Co-ordination of Admission Arrangements) (Secondary Schools) (England) Regulations 2002
|laid under the Schools Standards and Framework Act 1998;
|Office of Communications (Membership) Order 2002, laid under the Office of Communications Act 2002.
|Papers not subject to parliamentary proceedingsThe following papers were laid before the House and ordered to lie on the Table:
|Local Authority Permits for Part B Installations and Mobile Plant (England and Wales) Fees and Charges Scheme 2002, laid under of the Pollution Prevention and Control (England and Wales) Regulations 2000;
|First Report of the Parliamentary Commissioner for Administration, Session 200203, on Access to Official Information: Investigations Completed May to October 2002, laid under the Parliamentary Commissioner Act 1967;
|Report and Accounts for 200102 of the Churches Conservation Trust, laid under the Pastoral Measure 1983;
|Proposal for a draft Order in Council: Health and Personal Social Services (Quality, Improvement and Regulation) (Northern Ireland) Order 2003, laid under the Northern Ireland Act 2000.
Public Business
|Road Traffic (Amendment) Bill [HL]A bill to make provision with respect to the driving and use of vehicles drawn by horses or other animals on roads or in other public places; and for connected purposes was presented by the Lord Beaumont of Whitley, read a first time and ordered to be printed. (HL Bill 13)
|Business of the HouseIt was moved by the Lord Privy Seal (Lord Williams of Mostyn) that Standing Order 41 (Arrangement of the Order Paper) be dispensed with on Tuesday 10th December next to allow the motion standing in the name of the Lord McIntosh of Haringey to be taken before the National Minimum Wage (Enforcement Notices) Bill [HL]; the motion was agreed to.
|Human RightsIt was moved by the Chairman of Committees that a Select Committee of six Lords be appointed to join with a Committee appointed by the Commons as the Joint Committee on Human Rights:
To consider:
(a) matters relating to human rights in the United Kingdom (but excluding consideration of individual cases);
(b) proposals for remedial orders, draft remedial orders and remedial orders made under section 10 of and laid under Schedule 2 to the Human Rights Act 1998; and
(c) in respect of draft remedial orders and remedial orders, whether the special attention of the House should be drawn to them on any of the grounds specified in Standing Order 74 (Joint Committee on Statutory Instruments);
To report to the House:
(a) in relation to any document containing proposals laid before the House under paragraph 3 of the said Schedule 2, its recommendation whether a draft order in the same terms as the proposals should be laid before the House; or
(b) in relation to any draft order laid under paragraph 2 of the said Schedule 2, its recommendation whether the draft Order should be approved;
and to have power to report to the House on any matter arising from its consideration of the said proposals or draft orders; and
To report to the House in respect of any original order laid under paragraph 4 of the said Schedule 2, its recommendation whether:
(a) the order should be approved in the form in which it was originally laid before Parliament; or
(b) that the order should be replaced by a new order modifying the provisions of the original order; or
(c) that the order should not be approved,
and to have power to report to the House on any matter arising from its consideration of the said order or any replacement order;
That, as proposed by the Committee of Selection, the Lords following be named of the Committee:
L. Bowness
L. Lester of Herne Hill
L. Parekh
|B. Perry of Southwark
B. Prashar
B. Whitaker;
That the Committee have power to agree with any Committee appointed by the Commons in the appointment of a Chairman;
That the Committee have power to adjourn from place to place;
That the Committee have leave to report from time to time;
That the Committee have power to appoint specialist advisers;
That the minutes of evidence taken before the Committee from time to time shall, if the Committee think fit, be printed;
the motion was agreed to; and a message was ordered to be sent to the Commons to acquaint them therewith.
|Procedure of the HouseIt was moved by the Chairman of Committees that the Select Committee on Procedure of the House be appointed and that, as proposed by the Committee of Selection, the following Lords together with the Chairman of Committees be named of the Committee:
L. Alderdice
B. Blatch
V. Brookeborough
E. Caithness
L. Chalfont
L. Cope of Berkeley
L. Craig of Radley
L. Crickhowell
L. Denham
L. Donaldson of Lymington
L. Geddes
L. Gladwin of Clee
L. Goodhart
B. Goudie
|L. Grenfell
L. Grocott
L. Haskel
L. Irvine of Lairg (Lord Chancellor)
L. Judd
B. Rendell of Babergh
L. Roper
L. Strathclyde
B. Symons of Vernham Dean
L. Trefgarne
L. Waddington
B. Warnock
L. Williams of Crosby
L. Williams of Mostyn (Lord Privy Seal);
the motion was agreed to.
|Crime (International Co-operation) Bill [HL]It was moved by the Lord Filkin that the bill be now read a second time; after debate, the motion was agreed to and the bill was committed to a Grand Committee.
The House was adjourned at twenty minutes past six oclock
till tomorrow, half-past two oclock.


text:
By Ian Bush
PHILADELPHIA (CBS) — Comcast Corporation is starting a new service that aims to keep customers from straying to Netflix or other streaming video providers.
It's called Xfinity Streampix. For $5 per month (or included in some cable packages), Comcast says they'll deliver movies and full, past seasons of small-screen shows to your TV, computer, iPhone, or iPad.
The cable giant says that it's in addition to the tens of thousands of films and programs it offers "on demand."
Xbox 360 and Android apps are coming, as well.
Earlier this month, Verizon announced a tie-up with Redbox to start its own streaming service.
Netflix costs a bit more than Comcast's offering, but you don't have to pay a cable bill to be a member.
Netflix and Hulu also are trying out some original, scripted series in a stab at adding value.
Top Content On CBSPhilly
- PHOTOS: Summer's Hottest Concerts
- VIDEO: Latest News & Weather
- AUDIO: Podcasts & Shows
- NEWS: Top Headlines
- PHOTOS: View The Best Galleries

subset: commoncrawl


text:
Hotel Summary
Summary Page
Rooms & Prices
Rooms From £26.00
Customer Reviews
View Our Customer Reviews
Local Attractions
Local Attractions near Us
Welcome to Hendham House
Address: 3-4 Beech Mount, Harpurhey, Manchester, M9 5XS
Hotel Description
Set in quiet residential area, on the outskirts of Manchester city centre, Hendham House offers contemporary accommodation and free public parking. This guest house is 2 minutes' drive from the M60 motorway and 5 minutes' drive from the city centre. All the rooms at Hendham House have access to shared bathroom facilities. A cooked breakfast is served in the morning and evening meals, snacks, and tea and coffee can be enjoyed in the dining room. There are excellent transport links to M.E.N. Arena, Sports City, Printworks and Palace Theatre are within a 10-minute drive. Manchester Northern Quarter and Manchester Piccadilly Gardens are just over 2 miles away.
Our Facilities
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Attractions - Hendham House
Manchester City Football Club - Football Club
Distance 2.12 miles (3.39 km)
Manchester Centre - Town Centre
Distance 2.5 miles (4 km)


text:
All in all, The Year of the Snake feels like far greater value for money than the previous Zodiac Tournament and Nightmare in North Point DLCs. Although short in duration, it's a quality experience that's in-keeping with the main story, whilst providing players with an excellent reason to get back on the streets of Hong Kong.
After getting the snot kicked out of me in my first 3-on-1 brawl (it's been a few months since I've played!) I quickly Googled "How to fight in Sleeping Dogs" and set off to do what Wei Shen does best. From there on, this DLC was pure enjoyment, right up to the very last roundhouse.
Great game. Didn't know about this dlc. Might give it a try.


text:
Brady Foltz
No. 15 TCU Set For Big 12 Debut
Horned Frogs to open conference play Saturday at Kansas
2012 Preview: Foltz Anchors Offensive Line
Foltz and Fry both appear on watch lists for national awards
TCU vs. Samford - 8/30/14
Football, USATSI
2014: Started all 13 games ... helped key a TCU offense that finished second in the nation in scoring (46.5 points per game) and tied for fifth in total offense (533.0 yards per game) ... Horned Frogs set single-season school records for points (604), passing yards (4,240), total yards (6,929), first downs (331) and plays (1,038).
2013: Saw action in 10 games ... added depth on the offensive line while also contributing on special teams.
2012: Appeared in 12 of 13 games ... paved the way for TCU to accumulate 1,977 yards rushing and 13 rushing touchdowns ... TCU had three runners with at least 417 yards rushing ... helped TCU control the ball as it led the Big 12 in time of possession and rank eighth nationally at 32:44 minutes per game.
2011: Redshirted in his first season at TCU.
High School: Ranked by Rivals.com as the No. 41 guard nationally and No. 2 in the state of Kansas ... the 10th-ranked overall recruit in Kansas ... a 4A first-team all-state and all-league selection on the offensive and defensive lines as a senior and junior ... did not allow a sack his final two seasons ... totaled 101 pancake blocks his senior year as Rose Hill rushed for 3,500 yards ... totaled 21 tackles on defense with a sack and an interception return for a touchdown ... team captain and most valuable player ... a Wichita All-Metro selection and a member of the Wichita Eagle Top 22 ... a four-year letterman in football who also lettered three years in basketball and track and field.
Personal: Younger brother of former TCU offensive guard Blaize Foltz ... his father, Roger Foltz, played football at Wake Forest ... his mother, Heidi Foltz, was a basketball player at Fort Hays State ... chose TCU over Air Force and Colorado State.
Academics @TCUAASO
Baseball @TCU_Baseball
M Basketball @TCUBasketball
W Basketball @TCUWbasketball
Equestrian @TCUWEquestrian
Football @TCUFootball
M Golf @TCUMensGolf
W Golf @TCUWomensGolf
Rifle @TCURifle
Swimming & Diving @TCUswimdive
Soccer @TCUSoccer
M Tennis @TCUMensTennis
W Tennis @TCUWomensTennis
Track & Field @TCUTrackField
Beach Volleyball @TCUBeachVB
Volleyball @TCUvolleyball


text:
No Yao Ming or Tracy McGrady? No worries for the Houston Rockets on Sunday night when they took down the reigning-champeen Los Angeles Lakers, 101-91, at Staples Center. Without Ming, who is done for the season, and McGrady, recovering from left-knee surgery, Houston benefited from unlikely contributors Aaron Brooks (a career-high 33 points, including five three-pointers) and David Andersen (a career-high 19 points).
About Andersen, who hails from Down Under, Lakers coach Phil Jackson said, "We obviously didn't know the scouting report that well on Andersen. We knew he's a shooter, but we didn't see him playing at that level."
Take note, Alvin Gentry, when your Phoenix Suns travel to Texas to take on the Rockets (6-4). Good news for the NBA's current best team is that, before Houston stole the stage in L.A., the Rockets weren't really playing that well. The loss of two superstars is huge for any team, so the team's average start was to be expected.
Along with Brooks and Andersen, the Suns will have to deal with team-leading scorer Trevor Ariza and Houston's main man on the boards, Luis Scola. The Rockets like to get up and down the floor -- reference their 100-plus points scored in their past nine contests -- so Phoenix will need to be lights out from the floor to continue its totally hot start.
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Tip-off at Houston's Toyota Center is 6:30 p.m. TV: My45 (cable 9). Radio: KTAR-AM 620. More info: www.suns.com.


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St. Charles Community College Nursing Student
Hi. I am new to this website - I just registered today.
I am starting the nursing program at St. Charles Community College this Fall semester. I have read over the program information for both the lab and lecture and it looks pretty intense, especially the lab.
I see that a lot of outside practice is required for the labs. If anyone is interested in being a partner with me for the sake of practicing their labs, please let me know.
My class schedule is as follows:
Monday and Wednesday Lecture: 8 to 9:50am
Tuesday Lab: 2 to 4pm
Thursday and Friday clinicals starting at 7am until noon
I am not employed so I am pretty open.
I would love to make new friends for school. Let me know if anyone is interested in getting in touch - especially if we have the same class/lab schedules.
About ScccNursingStudent
Joined: Aug '06; Posts: 1Aug 15, '06Hello,
I'm Trying To Get Into The Lpn Program At Stchas Because It Seems So Difficult To Get Into The Rn Program. I Am Going There Tomorrow To Complete The Process. I Will Contact You To Let You Know The Outcome. Congrats And Hope To Talk To You Soon.Aug 19, '06I am interested in trying to find an online course to get my lpn license. Any suggestions?Aug 19, '06You must've been at orientation yesterday. I was sitting in the front row :-)
Unfortunately, I have none of your classes. Good luck finding someone. I live in the Troy area, am hoping to buddy up with some people.Aug 20, '06Hi! I was at orientation, too! I'm starting to feel pretty intimidated about the whole process.
I have lecture on Mondays and Wednesdays from 10:00 to 11:50.
My lab is on Tuesdays from 2:00 - 3:50
And I also have clinicals on Thursday and Friday mornings.
I think that lab is what is concerning me the most with passing all of the skills.
Although I work with a gal that made it through her first semester and was at the end of the second semester and got a 77.8% in a class and she was kicked out of the program! YIKES!
I'm pretty scared about juggling three children, and their schedules, a husband, and working nights on the weekends! I guess the positive way to look at it all is that the semester will go by faster if I am busy!Aug 21, '06I'm very excited. I can't believe I'm here!!!! I've been looking forward to this forever!Sep 8, '06hello!!!
I have lecture at 8am to 9:50 at SCCC. I guess I'm in your class. What is your name? I sit in the front row all the way over by the wall away from the door. My best friend sits next to me and she is also a member of this site. We live in St. Charles. My name is Sandi. I have clinicals in the mornings too. Where do you go?Sep 8, '06Hey I am gymrat33's best friend!!! I always go to the lab after class on Monday and Wednesday. We sit in the front of class all the way against the wall. Please let us know if you want to come in and practice with me. My name is Leslie by the way.Feb 7, '07I am trying to get in to the nursing program at SCCC for '08 (I have some pre-reqs I have to finish). How long is the wait list for the RN program?Feb 22, '08I start SCCC in August of this year. There is no wait list. I applied last August, after I completed all of the general classes, took the dosage test in January, and received my acceptance letter about two weeks ago. They accept the first 80 people to pass the test and meet all of the program requirements. If you haven't already applied, then I don't believe you can get in this year. But I see your post was made last year, so perhaps you've already applied and someone else can use this info.
I'd be interested to know if anyone else on here will be starting this August. I've very excited!!!Mar 5, '08Hello! This is my first time posting on this site. I registered last year and completely forgot. I got my letter a few weeks ago. I'm kind of excited and kind of worried. I'm a bit of a pessimist so I keep thinking the letter is a "maybe you got in" letter. It just seems so simple. I guess for all the stress I went through hoping to get in, I was expecting a gold ticket or something. LOL. So I'm still waiting for that final letter we are supposed to get, then maybe I will feel fully excited.
CongratulationsMar 10, '08Congratulations Uniscore1! Don't be pessimistic. If you received the letter, then you are in! I'm very excited, but I'm also anxiously awaiting the orientation packet. I want to go ahead and get a start on buying the supplies I will need. I was accepted at Flo Valley as well, and they have already sent me their instructions. Perhaps SCCC will send theirs soon.
Let me know when you get your packet, and I'll do the same for you.:spin:Mar 10, '08I just spoke to an admission secretary and was told that the letters will be sent out before Fall registration, which is in April.


text:
Buffalo Nickel
Call (828) 575-2844Directions
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At Buffalo Nickel, we strive to provide you with a warm and inviting atmosphere, free of pretense. A place where you can feel comfortable and relaxed as you join us for dinner or drinks.
Business Hours
Monday Closed
Tuesday 5:00 PM - 12:00 AM
Wednesday 5:00 PM - 12:00 AM
Thursday 5:00 PM - 12:00 AM
Friday 5:00 PM - 12:00 AM
Saturday 5:00 PM - 12:00 AM
Sunday 5:00 PM - 12:00 AM


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Mirrors like the HIB Aries Magnifying Bathroom Mirror are always handy. There are often times when you need to look just that little bit closer, and a normal mirror just won't do.
A Multi Functional Mirror
Magnifying mirrors like the HIB Aries one are often referred to as shaving or vanity mirrors. This is mainly because many people use them to either get a closer and more accurate shave, or simply to check what they look like in more detail. Lucky then that the HIB Aries Magnifying Bathroom Mirror has 3 x magnification. This way each time you look in it, you will see things 3 x closer.
Moves Around for Ease
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Your delightful HIB Aries Magnifying Bathroom Mirror could be yours not too far away. Contact Splash Direct to find out more.


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Head Coach Brant Tolsma
Coach's Corner with Brant Tolsma (Audio Interview)
Liberty is coming off its annual trip to Terre Haute, Ind., for NCAA Pre-Nationals. Sam Chelanga finished 2nd in the men's 8K white race Saturday, while the Flames finished 29th as a team. On the women's side, Liberty finished 33rd, with Dacia Bushman leading the way individually at 111th out of 249 runners. Recently, cross country coach Brant Tolsma sat down with Nick Pierce to discuss the results from Pre-Nationals and what's next for his squads as they prepare for Big South Championships.
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|ognizant Communication Corporation
The Regenerative Medicine Journal
Cell Transplantation, Vol. 16, pp. 489-494, 2008
0963-6897/08 $90.00 + 00
Copyright © 2008 Cognizant Comm. Corp.
Printed in the USA. All rights reserved..
A Preliminary Gene Expression Profile of Acute Graft-Versus-Host Disease
Matthew P. Buzzeo,1 Jie Yang,2 George Casella,2 and Vijay Reddy1
1Department of Medicine, Division of Hematology/Oncology,
University of Florida, Gainesville, FL, USA
2Department of Statistics, University of Florida, Gainesville, FL, USA
Allogeneic hematopoietic stem cell transplantation (HSCT) is the treatment of choice for high-risk hematological malignancies, yet a major complication associated with this therapy is acute graft-versus-host disease (GVHD). Despite a well-defined pathophysiological mechanism, there are no definitive markers for predicting acute GVHD development or progression to advanced stages. In the current study, we enrolled four acute GVHD and four acute GVHD-free recipients of allogeneic HSCT and collected peripheral blood just prior to onset of clinical acute GVHD for analysis on Affymetrix GeneChip® Human Genome U133 Plus 2.0 microarrays. We noted significant differences in expression of 1,658 genes between control and acute GVHD patients, based on an analysis of covariance (ANCOVA) by type of transplant, a pooled error estimate, and a false discovery rate (FDR) of 10%. In conclusion, we offer the first report of a preliminary molecular signature of acute GVHD in allogeneic HSCT patients.
Key words: Graft-versus-host disease (GVHD); Hematopoietic stem cell transplantation (HSCT); Microarray; Gene expression
Address correspondence to Vijay Reddy, M.D. Ph.D., at his current address: Florida Center for Cellular Therapy, Florida Hospital Cancer Institute, 2501 N. Orange Ave., Suite 581, Orlando, FL 32804, USA. Tel: 407-303-2070; E-mail: email@example.com
Prenatal Tolerance Induction: Relationship Between Cell Dose, Marrow T-Cells, Chimerism, and Tolerance
Jeng-Chang Chen,1 Ming-Ling Chang,2 Shiu-Feng Huang,3 Pei-Yeh Chang,1 Marcus O. Muench,4 Ren-Huei Fu,5 Liang-Shiou Ou,5 and Ming-Ling Kuo6
1Department of Surgery, Chang Gung Children's Hospital, Chang
Gung University College of Medicine, Taoyuan, Taiwan
2Department of Hepatogastroenterology, Chang Gung Memorial Hospital, Taoyuan, Taiwan
3Division of Molecular and Genomic Medicine, National Health Research Institutes, Miaoli, Taiwan
4Blood Systems Research Institute and Department of Laboratory Medicine, University of California, San Francisco, CA, USA
5Department of Pediatrics, Chang Gung Children's Hospital, Taoyuan, Taiwan
6Department of Microbiology and Immunology, Graduate Institute of Basic Medical Sciences, Chang Gung University College of Medicine, Taoyuan, Taiwan
It was reported that the dose of self-antigens can determine the consequence of deletional tolerance and donor T cells are critical for tolerance induction in mixed chimeras. This study aimed at assessing the effect of cell doses and marrow T cells on engraftment and tolerance induction after prenatal bone marrow transplantation. Intraperitoneal cell transplantation was performed in FVB/N (H-2Kq) mice at gestational day 14 with escalating doses of adult C57BL/6 (H-2Kb) marrows. Peripheral chimerism was examined postnatally by flow cytometry and tolerance was tested by skin transplantation. Transplantation of light-density marrow cells showed a dose response. High-level chimerism emerged with a threshold dose of 5.0 × 106 and host leukocytes could be nearly replaced at a dose of 7.5-10.0 × 106. High-dose transplants conferred a steady long-lasting donor-specific tolerance but were accompanied by >50% incidence of graft-versus-host disease. Depletion of marrow T cells lessened graft-versus-host disease to the detriment of engraftment. With low-level chimerism, tolerance was a graded phenomenon dependent upon the level of chimerism. Durable chimerism within 6 months required a threshold of >2% chimerism at 1 month of age and predicted a 50% chance of long-term tolerance, whereas transient chimerism (<2%) only caused hyporesponsiveness to the donor. Tolerance induction did not succeed without peripheral chimerism even if a large amount of injected donor cells persisted in the peritoneum. Neither did an increase in cell doses or donor T-cell contents benefit skin graft survivals unless it had substantially improved peripheral chimerism. Thus, peripheral chimerism level can be a simple and straightforward test to predict the degree of prenatal immune tolerance.
Key words: Cell dose; Chimerism; Graft-versus-host disease; Immune tolerance; In utero transplantation; T cell
Address correspondence to Jeng-Chang Chen, M.D., Department of Surgery, Chang Gung Children's Hospital, 5, Fu-Shin Street, Kweishan, 333, Taoyuan, Taiwan. Tel: +886-3-3281200, ext. 8227; Fax :+886-3-3287261; E-mail: email@example.com
Improved Xenogenic Hepatocyte Implantation Into Nude Mouse Liver Parenchyma With Acute Liver Failure When Followed by Repeated Anti-Fas Antibody (Jo2) Treatment
Isabelle Vidal,1,2 Nadège Blanchard,2,3 Eliane Alexandre,2 Arnaud Gandillet,2* Marie-Pierre Chenard-Neu,4 Frank Staedtler,5 Martin Schumacher,5 Philippe Bachellier,2,6 Daniel Jaeck,2,6 Huseyin Firat,7 Bruno Heyd,1,8 and Lysiane Richert1,2,3
1EA 3921, IFR 133, Faculté de Médecine et de
Pharmacie, Besançon, France
2Laboratoire de Chirurgie Expérimentale, Fondation Transplantation, Strasbourg, France
3KaLy-Cell, Témis Innovation, Besançon, France
4Service d'Anatomo-Pathologie, Hôpital de Hautepierre, Strasbourg, France
5Novartis Pharma AG, Biomarker Development, Basel, Switzerland
6Centre de Chirurgie Viscérale et de Transplantation, Hôpital de Hautepierre, Strasbourg, France
7Firalis SAS, Huningue, France
8Service de Chirurgie Digestive et Vasculaire, Hôpital Jean Minjoz, Besançon, France
Hepatocyte transplantation is a promising therapy for acute liver failure in humans. Recently, we succeeded in inducing various acute and chronic liver failures in nude mice. Engraftment of transplanted xenogeneic rat hepatocytes, visualized in the host liver by anti-MHC class I immunohistochemistry, revealed that liver repopulation was limited, and equivalent in nude mice with and without acute liver failure. In the present study, acute liver failure was induced in nude mice by a single injection of sublethal anti-Fas antibody Jo2, followed 24 h later by rat hepatocyte transplantation and than by a weekly repeated injection of Jo2. Rat hepatocyte engraftment into the recipient liver parenchyma 3 weeks following hepatocyte transplantation was about sevenfold increased when nude mice were subsequently subjected to weekly repeated Jo2 injection. Genomic analysis of these mice showed an overall transcriptome profile of upregulation of cellular cycle blocking transcripts, activation of liver injury inducing IFN-g/STAT1 pathway, and circadian transcript signature of antiproliferative cell status compared to mice submitted to hepatocyte transplantation only. The findings of the present study suggest that the induction of cell proliferation blockade in recipient livers could promote sufficient engraftment of transplanted hepatocytes to allow transient or definitive treatment of liver failure in humans.
Key words: Nude mice; Anti-Fas antibody treatment; Xenogeneic hepatocyte engraftment; Circadian genes; p21
Address correspondence to Lysiane Richert, Laboratoire de Biologie Cellulaire, EA 3921, IFR 133, Faculté de Pharmacie, 4, place Saint Jacques, 25030 Besançon Cedex, France. Tel: +33 3 81 66 55 52; Fax: +33 3 81 66 56 79; E-mail: firstname.lastname@example.com
*Present address: Stem Cell Research, Paterson Institute for Cancer Research, Christie Hospital NHS Trust, Manchester, UK.
Sertoli Cell Line Lacks the Immunoprotective Properties Associated With Primary Sertoli Cells
Jannette M. Dufour,1 Brinda Dass,1 Katie R. Halley,1 Gregory S. Korbutt,2,3 Doreen E. Dixon,2 and Ray V. Rajotte2,3
1Cell Biology and Biochemistry, Texas Tech University Health
Sciences Center, Lubbock, TX, USA
2Surgical-Medical Research Institute, University of Alberta, Edmonton, Alberta, Canada
3Department of Surgery, University of Alberta, Edmonton, Alberta, Canada
Sertoli cells are important for maintenance of the immune privileged environment of the testis and prolong survival of cotransplanted cells. The objective of the current study was to examine the immunoprotective properties of a mouse Sertoli cell line (MSC-1) in order to identify a Sertoli cell line that could be used to aid in investigation of the immunoprotective abilities of Sertoli cells. BALB/c islets were cotransplanted with 0-9 million primary BALB/c Sertoli cells or MSC-1 cells into diabetic C3H or BALB/c mice and protection of grafted islets was examined by monitoring blood glucose levels and immunohistochemical analysis. Additionally, expression of potential immunoprotective factors in MSC-1 cells was examined. Cotransplantation of islets with 3 million primary Sertoli cells significantly prolonged islet allograft survival (61.1 ± 6.9 days; p < 0.05) compared with control mice that received allogeneic islets alone (26.9 ± 2.1 days). Grafts collected from normoglycemic C3H mice at 100 days posttransplant contained insulin-positive b-cells adjacent to allogeneic Sertoli cells arranged in tubule-like structures. In contrast, cotransplantation of islet allografts with MSC-1 cells did not prolong islet survival (average 29.8 ± 3.3 days) regardless of the number of MSC-1 cells transplanted and the rejected grafts contained very few b-cells and randomly arranged MSC-1 cells. The lack of islet cell survival was not due to detrimental effects of MSC-1 cells because syngneic islets cotransplanted with MSC-1 cells were functional throughout the study. MSC-1 cells were found to express known Sertoli cell-expressed, immunoprotective factors, clusterin, Fas ligand, and transforming growth factor-b1, suggesting additional factors may be involved in Sertoli cell immune privilege. These data indicate the MSC-1 cell line lacks the immunoprotective properties associated with primary Sertoli cells. Further study of this cell line could be useful in examining the mechanisms that enable Sertoli cells to provide immune privilege.
Key words: Sertoli cell; Immune privilege; Islet; Transplantation; MSC-1
Address correspondence to Dr. Jannette M. Dufour, Cell Biology and Biochemistry, 3601 4th St. STOP 6540, Texas Tech University Health Sciences Center, Lubbock, TX 79430, USA. Tel: (806) 743-2616; Fax: (806) 743-2990; E-mail: email@example.com
A Rat Embryo Staging Scale for the Generation of Donor Tissue for Neural Transplantation
E. M. Torres,1 U. M. Weyrauch,1 R. Sutcliffe,2 and S. B. Dunnett1
1Department of Biosciences, Cardiff University, Cardiff CF10
2Charles River Laboratories, Research Models & Services, UK
In rat models of Parkinson's and Huntington's diseases, embryonic neural cells obtained from embryos of specified ages can be implanted into the brain to partially restore both physiology and function. However, in litters produced using overnight mating protocols (often from commercial suppliers), the embryonic age can be difficult to determine precisely. As a result, embryonic size based on crown to rump length (CRL) is usually a more reliable method of embryo staging than the day of mating. This approach is not without difficulty. There are a number of rat staging scales in the literature, none of which deal with donor ages younger than E13, and there are discrepancies between scales at some donor ages. In the present article, we have devised a short mating-period protocol to produce precisely aged embryos. We show that CRL is a highly accurate, reproducible index of donor age and we present an updated embryonic staging scale for Sprague-Dawley (CD) rats that includes donor ages younger than those previously reported.
Key words: Dopamine graft; Donor age; Embryo staging
Address correspondence to E. M. Torres, Cardiff University, Biomedical Sciences Building, Museum Avenue, PO box 911, Cardiff CF10 3US, UK. Tel: 00 44 (0)2920 874115; E-mail: firstname.lastname@example.com
Electrical Stimulation-Induced Release of <gk>b-Endorphin From Genetically Modified Neuro-2a Cells
Volker Storn,1*+ Michael Kirschbaum,1*# Burkhard Schlosshauer,1 Andreas F. Mack,2 and Cornelia Fricke1
1NMI Natural and Medical Sciences Institute, University of
Tuebingen, 72770 Reutlingen, Germany
2Anatomisches Institut, University of Tuebingen, 72074 Tuebingen, Germany
The quantity of therapeutic gene products released from genetically engineered cells can be controlled externally at different levels. The widely used approach of controlling expression, however, generally has the disadvantage that chemical substances must be applied for stimulation. An alternative strategy aims at controlling gene products at posttranslational levels such as secretion. The secretion of a therapeutic agent can be regulated if the agent is targeted to the regulated secretory pathway and stored in the secretory granules until its release. In this article we address the question of whether the release of b-endorphin, an opioid with a potent analgesic effect, could be induced by electrically stimulating stably transfected Neuro-2a cells. Throughout this study we used the human proopiomelanocortin (POMC) gene, which is the precursor molecule for human -endorphin. We analyzed its subcellular localization and found it in the regulated secretory pathway in Neuro-2a cells. Using electrical field stimulation we were able to identify a stimulation pattern that significantly increased the release of b-endorphin-immunoreactive material, although to a limited extent. This result indicates that electrical stimulation of secretion could be used to manipulate the amount of a therapeutic agent released from transplanted cells.
Key words: Electrical stimulation of secretion; Endorphin; Genetically engineered cells; Neuro-2a; Pain; Regulated secretory pathway
Address correspondence to Prof. Burkhard Schlosshauer, NMI Markwiesenstr. 55, 72770 Reutlingen, Germany. Tel: +49-7121-51530-20; Fax: +49-7121-51530-62; E-mail: firstname.lastname@example.com
*These authors contributed equally.
+Current address: Department of Dermatology, University of Heidelberg, Vossstr. 11; 69115 Heidelberg, Germany.
#Current address: Fraunhofer Institute for Biomedical Engineering, Am Mühlenberg 13; 14476 Potsdam, Germany.
Comparison of Human Serum With Fetal Bovine Serum for Expansion and Differentiation of Human Synovial MSC: Potential Feasibility for Clinical Applications
K. Tateishi,1 W. Ando,2 C. Higuchi,2 D. A. Hart,3 J. Hashimoto,2 K. Nakata,2 H. Yoshikawa,2 and N. Nakamura2
1Department of Orthopedics, National Hospital Organization
Kure Medical Center, Hiroshima, Japan
2Department of Orthopedics, Osaka University Graduate School of Medicine, Osaka, Japan
3McCaig Centre for Joint Injury and Arthritis Research, The University of Calgary, Calgary, Canada
The aim of this study was to evaluate the effect of human serum (HS) on growth and differentiation capacity of human synovium-derived mesenchymal stem cells (MSC) in comparison to cells grown in fetal bovine serum (FBS). Human MSCs were isolated from the synovium of knee joints of three donors and the cells were cultured individually in varying concentrations of allogenic HS or FBS. Bovine MSCs were isolated from synovium and cultured in the same manner. Cell proliferation was assessed by the tetrazolium assay after passage 3. The capacity for chondrogenic and osteogenic differentiation was investigated in specific media followed by 1,9-dimethylmethylene blue assay and alcian blue staining, or by alizarin red staining, respectively. Human MSCs proliferated significantly more rapidly in the presence of HS than with equivalent levels of FBS. Chondrogenic or osteogenic differentiation occurred to nearly identical levels in HS or FBS. The results of this study indicate that HS is superior for the culture of human MSCs compared with FBS in terms of cellular expandability, without losing chondrogenic or osteogenic differentiation capacity. Coupled with the advantage in eliminating the potential risk accompanied with the use of xeno-derived materials, pooled, well-characterized HS could be a useful reagent to promote cellular expansion for clinical synovial stem cell-based therapy.
Key words: Human synovial mesenchymal stem cells; Human serum; Cell proliferation; Differentiation
Address correspondence to Norimasa Nakamura, M.D., Ph.D., Department of Orthopedics, Osaka University Graduate School of Medicine, 2-2 Yamadaoka, Suita, Osaka 565-0871, Japan. Tel: +81-6-6879-3552; Fax: +81-6-6879-3559; E-mail: email@example.com
Riboflavin Inhibits IL-6 Expression and p38 Activation in Islet Cells
Lorenzo Cobianchi,1,2* Alessia Fornoni,1,3,4* Antonello Pileggi,1,5 R. Damaris Molano,1 Nahir Y. Sanabria,1 Jorge Gonzalez-Quintana,1 Nicola Bocca,1 Simona Marzorati,1 Elsie Zahr,1 Anthony R. Hogan,1 Camillo Ricordi,1,5 and Luca Inverardi1,3,5
1Cell Transplant Center, Diabetes Research Institute, Leonard
M. Miller School of Medicine, University of Miami, Miami, FL, USA
2Department of Surgery, Fondazione IRCCS "San Matteo" Hospital, University of Pavia, Italy
3Department of Medicine, Leonard M. Miller School of Medicine, University of Miami, Miami, FL USA
4Division of Nephrology, Leonard M. Miller School of Medicine, University of Miami, Miami, FL USA
5DeWitt Daughtry Family Department of Surgery, Division of Cellular Transplantation, Leonard M. Miller School of Medicine, University of Miami, Miami, FL USA
6Department of Microbiology and Immunology, Leonard M. Miller School of Medicine, University of Miami, Miami, FL USA
Riboflavin is a water-soluble vitamin that reduces the production of proinflammatory mediators and oxygen radicals. Because islet <gk>b-cells are very sensitive to oxidative stress and to cytokines, we investigated the possible cytoprotective effects of riboflavin on insulinoma NIT-1 cells and on isolated rodent islets. NIT-1 cells and islets cultured in the presence or absence of 10 mM riboflavin were studied at baseline and after exposure to cytokines (TNF-a, IL-1b, INF-g). Riboflavin treatment did not affect islet cell viability as assessed by flow cytometry for caspases activation. However, riboflavin prevented the cytokine-induced increase in IL-6 mRNA expression and p38 phosphorylation analyzed by real-time PCR and immunoassay, respectively. In summary, nontoxic doses of riboflavin prevent cytokines-induced p38 phosphorylation and IL-6 upregulation in islet cells. This observation, together with the safety profile of riboflavin in the clinical setting, makes it an appealing agent for islet cytoprotection in islet transplantation protocols.
Key words: Riboflavin; IL-6 p38; Cytoprotection; Pancreatic islets; Inflammation
Address correspondence to Luca Inverardi, M.D., Cell Transplant Center, Diabetes Research Institute, University of Miami Leonard M. Miller School of Medicine, 1450 NW 10th Avenue (R-134), Miami, FL 33136, USA. Tel: (305) 243-5347; Fax: (305) 243-4404; E-mail: firstname.lastname@example.com
*These two authors equally contributed to this work.
Improved Glucose Regulation on a Low Carbohydrate Diet in Diabetic Rats Transplanted With Macroencapsulated Porcine Islets
Horatiu V. Vinerean,1 Lawrence S. Gazda,1,2 Richard D. Hall,1,4 Albert L. Rubin,2,3 and Barry H. Smith1,2,3
1The Rogosin Institute-Xenia Division, Xenia, OH, USA
2The Rogosin Institute, New York, NY, USA
3New York Presbyterian Hospital and Weill Medical College of Cornell University, New York, NY, USA
4Bob Evans Farms, Inc., Columbus, OH, USA
Islet xenografts from porcine donors can reverse diabetes in experimental animal models and may be an alternative to human islet transplantation. We have recently reported the ability of porcine islets encapsulated in a double layer of hydrophilic agarose to maintain in vitro functional ability for >6 months. Although b-cells are capable of adapting their secretory capacity in response to glucose levels, evidence has shown that prolonged hyperglycemia can compromise this ability. The aim of the present study was to determine the effects of diet manipulation on the long-term regulation of blood glucose levels, and the preservation of functional islet in the macrobeads. Twenty-one streptozotocin-induced diabetic Wistar-Furth male rats were randomly assigned to two diets containing 64% carbohydrate (CHO) or 20% CHO. Groups of five to six animals assigned to either diet were implanted with either empty (EM) or porcine islet-containing macrobeads (PIM) and followed for 333 days. Observations included general condition, body weight, blood glucose, and food and water intakes. Monthly blood samples were collected for insulin and C-peptide analysis. The 20% CHO diet significantly lowered blood glucose values when compared with those of the 64% CHO groups for both the empty (14.94 ± 0.41 vs. 16.26 ± 0.42 mmol/L, respectively, p < 0.001) and islet macrobead recipients (12.88 ± 0.39 vs. 15.57 ± 0.85 mmol/L, respectively, p < 0.001). The different diets, however, had no statistically significant effects on the preservation of islet mass in the macrobead. Serum porcine C-peptide was detected throughout the experiment in animals receiving porcine islet macrobeads, regardless of diet. Diabetic rats fed a low carbohydrate level diet and transplanted with porcine islet macrobeads had improved total tissue glucose disposal and improved clinical parameters associated with diabetes.
Key words: Porcine islets; Xenotransplantation; Encapsulation; Diet
Address correspondence to Horatiu V. Vinerean, The Rogosin Institute-Xenia Division, 740 Birch Rd, Xenia, OH 45385, USA. Tel: (937) 374-3116; Fax: (937) 374-3261; E-mail: firstname.lastname@example.com
Efficient Delivery of Human Single Fiber-Derived Muscle Precursor Cells Via Biocompatible Scaffold
Luisa Boldrin,1,5*+ Alberto Malerba,1,5* Libero Vitiello,2 Elisa Cimetta,3 Martina Piccoli,1 Chiara Messina,1 Pier Giorgio Gamba,4 Nicola Elvassore,3 and Paolo De Coppi1,5
1Stem Cell Processing Laboratory, Department of Paediatrics,
University of Padova, Padova, Italy
2Gene Transfer Laboratory, Department of Biology, University of Padova, Padova, Italy
3Department of Chemical Engineering, University of Padova, Padova, Italy
4Paediatric Surgery, Department of Paediatrics, University of Padova, Padova, Italy
5Surgery Unit, Institute of Child Health, University College of London, London, UK
The success of cell therapy for skeletal muscle disorders depends upon two main factors: the cell source and the method of delivery. In this work we have explored the therapeutic potential of human muscle precursor cells (hMPCs), obtained from single human muscle fibers, implanted in vivo via micropatterned scaffolds. hMPCs were initially expanded and characterized in vitro by immunostaining and flow cytometric analysis. For in vivo studies, hMPCs were seeded onto micropatterned poly-lactic-glycolic acid 3D-scaffolds fabricated using soft-lithography and thermal membrane lamination. Seeded scaffolds were then implanted in predamaged tibialis anterior muscles of CD1 nude mice; hMPCs were also directly injected in contralateral limbs as controls. Similarly to what we previously described with mouse precursors cells, we found that hMPCs were able to participate in muscle regeneration and scaffold-implanted muscles contained a greater number of human nuclei, as revealed by immunostaining and Western blot analyses. These results indicate that hMPCs derived from single fibers could be a good and reliable cell source for the design of therapeutic protocols and that implantation of cellularized scaffolds is superior to direct injection for the delivery of myogenic cells into regenerating skeletal muscle.
Key words: Human single fibers; Muscle precursor cells; Biocompatible scaffold; Muscle regeneration
Address correspondence to Paolo De Coppi, M.D., Ph.D., Surgery Unit, Institute of Child Health, 30 Guilford Street, London, WC1N 1EH, UK. Tel: +44 020-7905-2641; Fax: +44 020-7404-6181; E-mail: firstname.lastname@example.com
*L. Boldrin and A. Malerba equally contributed to this work.
+Current address: The Dubowitz Neuromuscular Unit, Hammersmith Hospital, Imperial College London, Du Cane Road, London W12 0NN, UK.


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2011-05-04 48 7
Wed 4 May 2011 in 48,7:
Near Bötzingen, 10 km to the northwest of Freiburg. The hash appears to be on a field, some 20 m from the nearest road.
Hijackal happens to be in Freiburg, with his bike (badly needing repair). Depending on how much work there is today, he hopes to get there in the evening.
There was no work left for the day with still plenty of daylight to go, so Hijackal cycled to the hash. The first half of the trip was easy riding along the Dreisam. Then, Hijackal learned that just because something is a field does not mean it has to be flat. Of course, he could have known: there's lots of wine from around here, and vineyards can be pretty steep.
The hash itself was in an actual vineyard, not really accessible from the road, but not fenced in either. Hijackal asked the lady just leaving the vineyard for permission to enter the vines; she didn't really seem to care about what I wanted to do there - she just commented that I should have come earlier to help her, as she was just leaving from a day's work in the vineyard. If noone had been there, Hijackal would have probably entered the vineyard anyways, so no Ambassador achievement for now...
On the way back, Hijackal took a slightly different path, going for the Tron, but forgot that he had taken a wrong turn on the way to the hash, so he hit his imaginary Tron wall at 30 km/h, luckily without any real damage...
Sorry, forgot the Stupid Grin. Still practicing...
| Hijackal earned the Land geohash achievement
| Hijackal earned the Bicycle geohash achievement


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Technology is grand.
This is how we've been talking to dad for the past two weeks. It's been a long two weeks too! We miss the man! Good thing he's coming home today.
Some pictures from John's biz trip to Scotland.
(click on this one to enlarge, it's really gorgeous)
the castle
typical street


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Locations of Spice and Herbs Store Near Me:
Bazaar Spices Union Market Location
1309 5th Street NE
Washington, DC 20002
M - Closed
Tu - 11am - 5pm
Wed - Fri - 11am - 7pm
Sat - 9:30am - 6:30pm
Sun - 9:30am - 6pm
Phone: 202-379-2907
Located in Union Market the beautiful DC artisanal food hall in the third row of merchants from the entrance near Red Apron and Cordial Fine Wines. This location carries a huge selection of exotic and hard-to-find spices, herbs, botanicals, and spice blends, beans, rices, and lentils, and other specialty food products.
Bazaar Spices Atlantic Plumbing Location
2130 8th Street NW
Washington DC 20001
M - Closed
Tu - 11am - 5pm
Wed - Sat - 11am - 6:30pm
Sun - 11am - 5pm
Located in the visually stunning Atlantic Plumbing building, in the histortic and artistic heart of Washington DC, this location is our full service artisan food studio and event space. In our Atlantic Plumbing location we offer our huge selection of exotic and hard-to-find spices, herbs, botanicals, and spice blends, beans, rices, and lentils, and other specialty food products such as artisanal honeys, and oils. In addition, we serve a full menu of hand-crafted spice and herbal infusions, as well as custom made-to-order blending and fresh spice grinding services.
The Atlantic Plumbing space is a beautiful venue for unique office off-sites and team building activities such as our Salt Tastings, Spice 101 and "Smell Me" classes, as well as cooking demos such as our "Everyday Ethiopian" or "Indian Cooking Basics". If interested in using the space for your next off-site or team building please contact us.
Online Spice Shop
In addition to our physical locations you can always buy spices online through our online spice, herb, and botanical shop. We utilize Paypal Payment processing so you can be assured that your transactions are always safe and secured.


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Lesson 39
Parts of Speech - Adjectives
There are a few adjectives that are irregular in their comparisons. Examples: good, better, best.
Instructions: Give the comparative and superlative forms of the following words.
1. many
2. ill
3. much
4. perfect
5. bad
--For answers scroll down.
1. many, more, most
2. ill, worse, worst
3. much, more, most
4. perfect - cannot be compared since there is no more perfect or most perfect.
5. bad, worse, worst
DAILY GRAMMAR - - - - by Mr. Johanson
Copyright 2014 Word Place, Inc - - All Rights Reserved.
For your convenience, all of our lessons are available on our website in our
lesson archive at http://www.dailygrammar.com/archive.html. Our lessons are
also available to purchase in an eBook, a FlipBook, and a Workbook format.
Daily Grammar Lessons Search


text:
By Lise Alves, Senior Contributing Reporter
SÃO PAULO, BRAZIL – The proposed amendment of a limit on public spending and the Brazilian government's effort to reform social Security are important factors for restart of economic growth in the country, says the latest Fiscal Monitor report released by the International Monetary Fund (IMF) on Wednesday.
According to the IMF although the country's turbulent political scenario constitutes a source of uncertainty the Temer Administration has pressed ahead with the necessary reforms.
"They have recently this week, at the highest level, reaffirmed their determination to continue with the reforms, pressing ahead with pension reform, in particular," said Oya Celasun, Chief of the World Economic Studies Division, earlier this week in a press conference at IMF Headquarters in Washington.
"If they are successful in implementing that, that should set the stage for returning fiscal finances to a much healthier setting and also putting a strong foundation for a return to stronger growth in Brazil," concluded Celasun.
The report predicts that Brazil will emerge from a full two-year recession in 2017 and grow by 0.2 percent. By 2020 the country should start to register primary surpluses. The international entity also says that freezing expenditures in real terms will help to reduce the deficit although the ratio of gross debt to the GDP is likely to continue to grow until at least 2022.
Finance Minister Henrique Meirelles arrived in Washington DC on Wednesday to attend annual meetings at the IMF and the World Bank. According to Meirelles' office the Finance Minister will meet with officials of these international organizations and discuss the reforms to be implemented in the country.


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Health and Human Services Secretary Kathleen Sebelius spent the week both in front of a Congressional panel and behind plenty of wisecracks from both late night comics and Saturday Night Live.
Alec Baldwin simply sees her as a gutsy politician willing to take accountability for the disastrous ObamaCare rollout.
By doing what, exactly, is unclear, since she will report to duty as usual come Monday morning despite being the public face of a fiasco unlike many others in modern politics.


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July 03, 2013 12:14 ET
TOWNSHIP OF BONFIELD, ONTARIO--(Marketwired - July 3, 2013) - Residents of the Township of Bonfield could soon lose the important services of municipal workers after the Mayor and Town Council started the countdown to lock out their own workers, if mediation talks on July 12th fail to produce a contract settlement, warned the Canadian Union of Public Employees (CUPE), representing 15 municipal workers in Bonfield.
"We've been trying to reach a negotiated settlement since our last contract expired December 31, 2011," said Steve Boyle, CUPE National Representative. "Every time we get to the table, the employer keeps demanding concessions that would roll back several provisions in the collective agreement, including attacks on seniority, training, employment security, scheduling, vacations, overtime, sick-leave and benefits."
"Our members have never had a strike or lockout in this community, and they don't want one now," says Boyle. "Previous rounds of negotiations when we dealt directly with the employer went a lot smoother - it's hard to reach a negotiated settlement when the Council is using a high-priced Toronto lawyer who wants to rewrite the collective agreement. At some point residents will want to ask themselves why the Township is spending thousands of dollars a day on an outside lawyer to negotiate a contract covering fifteen workers. From what's posted on their website, it looks like the lawyer has already cost the Township over $40,000, and we haven't even gotten to mediation yet."
A lockout would suspend roads maintenance, landfill and recycling services, applications and issuing of building permits, planning services, parks and recreation, tourism, by-law enforcement, health and safety, and all Township office services, since all municipal employees in Bonfield are represented by CUPE.
"Our members are residents too, and neighbours and friends of Bonfield taxpayers - the last thing they want is a service disruption," said Boyle. "That's why we are reaching out to the community, and asking residents to contact Mayor McLaren and the other councillors, to tell them to return to the bargaining table and do what it takes to reach a fair settlement for workers and for Bonfield, and one that will protect municipal services."
CUPESteve BoyleNational Representative705-474-9765CUPERobert LamoureuxCommunications905-739-3999
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Ricardo Sanchez, the former commander of U.S. forces in Iraq, filed paperwork Wednesday to run for the open U.S. Senate seat in Texas in 2012.
"I believe Texas needs a strong, independent voice to address the enormous challenges we are facing -- leadership that focuses on results rather than politics," Sanchez, a Democrat and former Army lieutenant general, said in a statement released by his campaign.
Sanchez, who now lives in San Antonio, said he'll make a formal public announcement in the coming weeks.
The Democratic Senate Campaign Committee has identified Texas as one of the six Republican-held seats the party hopes to pick up in 2012. Democrats hold a slim 53-47 majority in the chamber, and must defend 23 of their seats next fall.
Democrats see changing demographics as reason for optimism in Texas, a state where for decades the party hasn't had much success. New census data showed that the Latino population grew 42% in Texas from 2000 through 2010, and now accounts for more than a third of the overall population.


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There's a certain artistry to proper day drinking, especially in LA, where finding the best bar for every hour of sunlight in Summer can be crucial to your Funday ambitions. This should help: our first-ever guide to LA day drinking, complete with the best bar to drink at for every hour of daylight.
Fine print: This isn't for crawling purposes (obviously, that would be impossible geographically), but instead it's-whatever-o-clock-and-I'm-ready-to-start-daydrinking-what's-the-absolute-best-place-I-could-be-doing-it-at-this-very-minute purposes. Good luck.
The Definitive Eggnog Recipe You Need for the Holidays
Where to drink: The Drawing Room (address and info)
Why?: There are only a handful of bars actually open right when it's legal to serve at 6am, and most of them are dives, but none of them are as gloriously divey as this Los Feliz institution, where you're guaranteed to get your all-day drink-a-thon started right with 1) super-strong drinks, and 2) ultra-charming characters.
Where to drink: The Breakfast Bar (address and info)
Why?: Because this place is called Breakfast Bar. But also because they've got chicken-and-waffle sticks to help you set a day-base, and $3 Miller High Lifes to help you put that base to good use.
Where to drink: Playa Provisions (address and info)
Why?: Their house Bloody Marys. But also this new Top Chef-testant-run spot (the first of many by-the-sea places on this list, 'cause, duh) has you covered on the most substantial breakfast front (where you'll need to be covered at some point): their ciabatta breakfast sandwich is stuffed with (deep breath) sausage, bacon, avocado, eggs, pickled collard greens, Gruyere, and house-pickled habanero hot sauce. Pro tip: spoon some of the hot sauce into your Bloody.
Where to drink: Molly Malone's (address and info)
Why?: Because it's an institution. Because it has Guinness on draft. Because it's open. And because it's in the middle of the city, which means whether it's where you're starting the day or where you'll end up in the middle (or both!), it's convenient for someone to meet you and join you for at least one pint.
Where to drink: Open Air Kitchen + Bar (address and info)
Why?: Formerly Fatty's Public House, this Fairfax gastrobistro has a killer build-your-own-Bloody bar, which's probably right in your boozy wheelhouse around 10am.
Where to drink: Hungry Cat (address and info)
Why?: This by-the-ArcLight spot isn't just a great hidden-away treasure where you can get your drink on before a movie, but it also has brunch with killer oysters on weekends, which -- at 11am, and after a few tipples -- is kinda the perfect snack.
Where to drink: Alcove Cafe/Big Bar (address and info)
Why?: It's time to graduate to full-on, tomato-juice-free cocktails (hooray for noon!), and the Alcove's attached little bar, Big Bar, is the perfect transition spot: fresh-ingredient-filled, brunch-friendly mixed drinks like the Cockney Sparrow (Beefeater, rose tea, lemon, cucumber, Champagne) comprise the menu, and the patio's one of those you-could-spend-hours-out-there-and-not-even-notice gems.
Where to drink: Stark Bar (address and info)
Why?: It's time for something more substantive on both the food and drink side, and Stark Bar at LACMA -- one of our favorite patios to drink at in the city -- offers both: a full-on drink menu with fruit-mushing, high-end-boozing greatness, and flatbreads with pickled artichokes and gourmet sausage that'll beat back the hunger that's no doubt yearning to break free.
Where to drink: O'Brien's (address and info)
Why?: This Santa Monica Main St staple may be brotacular, but it's also got a great mid-afternoon happy hour, with $3.50 domestics from 12-7pm.
Where to drink: Golden Road Brewing (address and info)
Why?: You're probably at the point in your day where you're like: "drinking is fun. But you know what's more fun? Drinking... and playing games at the same time!" That's where Golden Road comes in: they've got giant Jenga, ping pong, and more, a slew of outdoor seats, and some of LA's best local beer, brewed right there.
Where to drink: Tropicana Bar at the Roosevelt (address and info)
Why?: The sun is high, you're ready to get half-naked, and you'd like to see people much better looking than you do the same. Thankfully, the Tropicana at the Roosevelt -- sometimes a list-y place at night -- is much easier to get into during the day, as are a bunch of other options from our list of LA's best pool bars.
Where to drink: The Whaler (address and info)
Why?: The beachside staple's just finally finished their renovations, which means you can just finally get tap Negronis and bourbon-and-IPA-based California Kings, plus late-afternoon bites including their house banh mi.
Where to drink: Mercado (address and info)
Why?: Now's when you want chips and guac. Now's when you want happy hour margaritas. Here's where you're going to get them.
Where to drink: The Bungalow (address and info)
Why?: There's no better place to watch the sunset, cheers a day of drinking well done... and figure out where the hell you're going for the night.
This list -- and all the rest -- look even sexier in our iPhone app. Get it now!
Jeff Miller is Thrillist LA's Senior City Editor and probably won't be seeing you for that 6am drink, but'll totally meet you out at 4pm. Follow him on Twitter and Instagram.
1. The Drawing Room1800 Hillhurst Ave, Los Angeles
2. The Breakfast Bar70 Atlantic Ave, Long Beach
3. Molly Malone's Irish Pub575 S Fairfax Ave, Los Angeles
4. Open Air Kitchen + Bar892 N. La Cienega, Los Angeles
5. Hungry Cat1555 Vine St, Los Angeles
6. Big Bar1927 Hillhurst Ave, Los Angeles
7. Ray's & Stark Bar5905 Wilshire Blvd, Los Angeles
8. O'Brien's Irish Pub & Restaurant2941 Main St, Santa Monica
9. Golden Road Brewing5410 W San Fernando Rd, Los Angeles
10. Tropicana Bar at the Roosevelt Hotel7000 Hollywood Blvd, Hollywood
11. The Venice Whaler10 Washington Blvd, Venice
12. Mercado1416 4th St, Santa Monica
13. The Bungalow101 Wilshire Blvd, Santa Monica
There are only a handful of bars actually open right when it's legal to serve at 6am, and most of them are dives, but none of them are as gloriously divey as this Los Feliz institution, where you're guaranteed to get super-strong drinks and ultra-charming characters.
Head out to this Long Beach hot spot for (surprise!) breakfast, especially for their chicken-and-waffle sticks, and hang around for happy hour, when you can get $3 High Life bottles.
Malone's is a West Hollywood institution with Guinness on draft, friendly vibes, and tasty bar food to scarf down in between games of darts.
This West Hollywood haunt is never a bad option for drinks, with a menu loaded with numerous wines, beers, and cocktails; but the real treat is their edibles menu, featuring options like prosciutto, fig, and arugula salad and a kale and spinach pizza with Parmesan cream sauce.
This slick, beachy seafoodery serves up raw bites like oysters, along with cooked fishes, burgers, and artfully mixed 'tails. Whether for lunch, brunch, or dinner, The Hungry Cat has been the go-to for inventive, LA-style seafood dishes for over a decade. Do it up by starting with a 1-, 2-, or 3-tier seafood platter, and pair your meal with one of the market-fresh cocktails that complement basically everything on the menu.
Big Bar's actually, well, a tiny little bar attached to the massive outdoor patio at the Alcove Cafe. It has a European feel thanks to a room-length, extra-wide marble bar, antique-looking oak cabinets, and custom-made, metal chandeliers.
Located at LACMA, this swanky bar and restaurant takes museum dining to new levels with an upscale American menu, killer cocktails, and an expansive outdoor patio. Expect wood-fired pizzas, plenty of veggie plates, and classic entrees like a burger with caramelized onions and grilled fish. The Stark Bar has an impressive spirit selection sourced from across the world, and the craft cocktails taste just right at happy hour.
This Santa Monica pub may get a little brotastic, but they also serve up delicious bar fare and a terrific mid-afternoon happy hour, with $3.50 domestics from 12-7pm.
Golden Road is the perfect place for anyone who loves drinking while playing games, because they've got giant Jenga, ping pong, and more, plus tons of outdoor seats, and some of LA's best local beer that's brewed right there. Enjoy a pint with some of the venue's delectable globally-inspired pub fare.
With its breezy palm trees and sleek design, the Tropicana Bar blends old Hollywood glamour with contemporary California cool. Guests can sip on refreshing mimosas and fresh fruit smoothies, enjoy live DJ music, or simply float in the pool and watch the Hollywood elite in action. Be sure to check out the underwater mural painted by David Hockney.
A Venice landmark, this beachside spot has been serving up market-fresh dishes and high-quality craft cocktails since the '40s. Be sure to try the fish tacos, or split some of their small bites or an artisan pizza with your group -- a group you should also convince to join in the Whaler's Monday night karaoke. While you're there, you'll want to head up to the second-floor patio bar for some gorgeous ocean views, particularly at sunset.
Mercado is a modern-tinged Mexican joint steeped in luxury woods, leathers, and steel, with a menu that boasts tons of authentic, South-of-the-border food and drink. This includes handmade tortillas, enchiladas with sweet shrimp and yellow mole, slow-cooked carnitas, and more than 70 tequila options.
This sprawling, indoor/outdoor lounge at the Fairmont Santa Monica is rustic, bougie-in-a-good-way, and straight-up charming. The beautifully designed patio is decked out with lanterns and close enough to the beach (aka, right across the street) to catch the ocean breeze. Accouterments like a fire pit and ping pong table make The Bungalow a great place to start the night with a few happy hour drinks.


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Bob Bledsaw RIP
James Mishler has a sad report to make this morning:
It is with great sadness that I must pass on the news that Robert Bledsaw, founder of Judges Guild, creator of the Wilderlands of High Fantasy, died this morning in Decatur, Illinois.
Bob was at his son's home, surrounded by family and loved ones, and passed on to the Great Adventure peacefully.
Bob was a good man, a creator of worlds, and a great friend.
I knew Bob had terminal cancer, that's what sparked my desire to reread old Judges Guild magazines (see this post from February Judges Guild Magazines Bring Back Memories). However it is still a very sad to lose him. I'll be the first to admit that Judges Guild product quality was quite variable, but it was there when nothing else was. Judge Guild adventures -- not to mention the City-State of the Invincible Overlord and the Wildnerlands of High Fantasy campaign setting -- jump started many Original D&D and AD&D campaigns back in the late 1970s.
Even Gary Gygax and TSR recognized this. Gary said this in the first edition Dungeon Master's Guide:
Bob Bledsaw of Judges Guild must also be given credit. He and his associates have certainly contributed to the overall improvement of fantasy adventure gaming, making the undertaking easier and encouraging still more interest in role playing.
We've lost of two the tabletop roleplaying game founders is less that 60 days. 2008 is shaping up to be a sad year for roleplaying gamers, especially oldtimers like me whose remember the early days of our hobby. My condolences to Bob's family and his many friends.
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In January 2014, the LGBTQIA Commission Scholarship Fund was created to 'provide scholarship support to active members of the LGBTQ (Lesbian, Gay, Bisexual, Transgender, Queer) Northern Arizona University community'. This is the first official scholarship at NAU geared towards the LGBTQ population.
To qualify as an 'endowed scholarship' that will generate funds in perpetuity, the scholarship fund must reach a minimum of $25,000.
*Please note, the scholarship is still being funded and currently is unable to accept applications. Please help spread the word to help us reach our fundraising goal so we can begin distributing awards!*
Additional regional and national LGBTQ scholarship resources may be found here on the Financial Aid website.
Once funded, scholarship applications will be considered in Spring Semesters and awards will be distributed the following academic year.
(Preference may be given to student(s) demonstrating financial need.)
Contributions can be made through the NAU Foundation online by selecting Fund #5375. Student organizations or other groups who wish to gain more information, please contact us at email@example.com


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It's All Good
4 Bedrooms, 3 Baths, Sleeps 8
It's All Good
- ASCII Whitewater: 3 - 10 miles
- ATV trails: 3 - 10 miles
- Bathroom BR1: Shared
- Bathroom BR2: Shared
- Bathroom BR3: Shared
- Bathroom BR4: Shared
- Bedding rm1: Queen w/TV
- Bedding rm2: Queen w/TV
- Bedding rm3: 2 Twins w/TV
- Bedding rm4: Queen w/TV
- Biking: Nearby
- Blender
- Boating: Nearby
- Ceiling Fans: 5
- Coffee Maker
- Covered Porch
- Crock Pot
- Cross Country skiing: nearby
- Deck
- Deck Furniture
- Deep Creek Lake: nearby
- Dishwasher
- Downhill skiing: 3 - 10 miles
- Firepit
- Fireplace
- Fishing: nearby
- Free Unlimited Long Distance
- Golfing: 3 - 10 miles
- Grill: Charcoal
- High Speed Internet: Cable
- Hiking: Nearby
- Horseback Riding: 3 - 10 miles
- Hot Tub
- Hot Tub: Outdoors
- Hunting: Less than 3 miles
- Internet Access
- Iron/Ironing Board
- Kayaking: 10+ miles
- Lake Area
- Level
- Level BR2
- Level BR3
- Level BR4
- Level BR5
- Linen Ready
- Microwave
- Night Club: 3 - 10 miles
- Offlake
- Outdoor Games
- Pet Friendly
- Place Servings: 8
- Pool Table
- Prestigious Homes
- Rafting: 10 + miles
- Restaurants: Less than 3 miles
- Snowmobiling: 3 - 10 miles
- State Forest
- Stereo
- Stove: Gas
- Swimming Pool: 3 - 10 miles
- Tea Kettle
- Television-LR: Large Screen
- Tennis: 10+ miles
- Toaster
- TV BR2: Standard
- TV BR4: Standard
- TV-BR1: Standard
- Washer and Dryer
- Wireless Internet
- With A/C
Reviews Write a Review
Stayed in January, 2014
Left on Feb 6, 2014 for a stay in Jan 2014 We were very pleased with It's all Good. We especially appreciated the large mud room area. We cooked during our stay and thus would have liked a little better quality of cookware. Overall, it was a good property and we would certainly consider returning their in the future. This review is the subjective opinion of a TripAdvisor member and not of TripAdvisor LLC. Your response: "Thank you for being our guest and for posting your review. While we have generally had positive comments about the stocked kitchen at It's All Good, we will certainly look into the kitchen cookware as the homeowner has a ton of owner pride and would not be pleased if his cookware were not up to the standard of the rest of his log cabin. We shall check further into this, thank you." This response is the subjective opinion of the management representative and not of TripAdvisor LLC.
Stayed in October, 2014
Left on Oct 22, 2014 for a stay in Oct 2014 My children, grandchildren and I spent a glorious weekend in this home. Though it was rainy and chilly outside, it was warm and sunny on the inside. The home was clean, well equipped and spacious. We all agreed that this would be a great place to return to on another occasion. This review is the subjective opinion of a TripAdvisor member and not of TripAdvisor LLC.
Stayed in November, 2014
Cozy charming log home in the woods Left on Dec 10, 2014 for a stay in Nov 2014 My family, comprising six adults, spent the long Thanksgiving weekend at "It's All Good" and thoroughly enjoyed the home and the surrounding area. The home was clean, comfortable and well-equipped. I was charmed by the log home construction. The hot tub, pool table and wi-fi were much appreciated. Just up the road was a hiking trail entrance. We explored there a few times and also walked down to the lake. I found Offlakes Rentals to be wonderful to deal with. They anticipated all our concerns and questions. Snow was forecast for our visit and we were asked our arrival time to ensure that the driveway was plowed. Much snow fell and the driveway was plowed again during our stay. This review is the subjective opinion of a TripAdvisor member and not of TripAdvisor LLC. Your response: "Thank you for your kind words, Fred. It is so much easier for Offlake Rentals to exceed expectations when our rental guests are as responsive as you at advising us of arrival time so that we can have your cabin ready and access in order. Certainly it sounds as though you took advantage of the location of It's All Good and it's nearby walking trails. While heavy snow this early in the season is rare, it is quite a treat! We look forward to accompanying your family again in the future! Keep hold of that 'repeat guest' coupon code you should have received by email!" This response is the subjective opinion of the management representative and not of TripAdvisor LLC.
Stayed in January, 2015
Left on Jan 26, 2015 for a stay in Jan 2015 Great weekend! The house was awesome, the rental company was attentive, overall excellent weekend. We will be back! This review is the subjective opinion of a TripAdvisor member and not of TripAdvisor LLC.
Stayed in December, 2014
Left on Feb 2, 2015 for a stay in Dec 2014 1 people found this review helpful This cabin was prefect for our family Christmas. It was large enough for all of us to have our own space, and at the same time to feel very close to each other. I will never forget the sound of my grand children running down the steps to see if Santa Claus had visit. This review is the subjective opinion of a TripAdvisor member and not of TripAdvisor LLC.
Stayed in December, 2015
Just got back from one of the best Thanksgivings ever! Our two sons, daughter-in-law, 2 grandchildren and 11 year old dog spent Thanksgiving week here and all really enjoyed themselves. The location is great with plenty of room for all. It being fall, we had a great view of the lake even though it's not lakefront. I was really impressed with how comfortable the beds and furniture were. We had no problem preparing our special meal as there was plenty of pots, pans, & dishes. All of us enjoyed the Discovery Center and hiking in the woods. We have rented homes at Deep Creek at least a dozen times but not with Offlake realty before. The staff was great! We will definitely rent through them again and would like to rent this particular property again.
Rates shown are based on a 4-night stay; shorter duration stays incur a nightly rate increase while nightly rate decreases for longer stays


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John Wessman, the real estate developer who plans to turn two Downtown Memphis buildings into boutique hotels, has been charged with bribery in a Palm Springs, California, corruption case.
An Atlanta-based restaurant that specializes in grassfed burgers is planning a new location in Memphis.
In a special staff meeting this week at The Commercial Appeal, USA Today Network executive and president of The Tennessean newspaper Laura Hollingsworth was asked whether The CA's corporate parent might sell its longtime home at 495 Union Ave.
Medical device company NuVasive Inc. has been approved for an 11-year tax incentive that will allow them to invest $116 million into their southeast Memphis facility and create 15 net new jobs.
When Wessman Development came to town last year with the idea of a boutique hotel, the Palm Springs, California company was part of the flood of smaller hotel projects Memphis was seeing and is still seeing. Then the company added another hotel and just this month the redevelopment of a building on Madison west of Second Street as apartments with retail on the ground floor. In a very short period of time, Wessman has had a lot of plans for Memphis.
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Ballet Memphis will present its winter mixed-repertory show, "Places Beyond," Friday through Sunday, Feb. 17-19, at Playhouse on the Square, 66 S. Cooper St. The show includes two new original works and a reprise of "Angels in the Architecture." Visit balletmemphis.org for show times and tickets.
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The dancers at Memphis's Ballet On Wheels Dance School are celebrating Black History Month in an innovative way this year. In conjunction with the Memphis Public Library, Ballet On Wheels has launched an interactive, monthlong series called "Groundbreakers: African-American Ballerina Stories of Triumph and Struggles," that invites Memphians to consider the history and future of ballet in a new light.
NASHVILLE – Calling the appointment of a board of trustees a "historic" and "essential" step for the University of Memphis, president M. David Rudd says the autonomous board will enable the university to control its own destiny.
Joe Dallesandro has "practically never" done the kind of question-and-answer session he did Thursday, Feb. 15, at the Memphis Brooks Museum of Art.
Mary Jo Pakkala, a second-year pharmacy student at the University of Tennessee Health Science Center, gives a blood pressure screening to 24-year-old Olivia Marshall at the Fred's on Lamar Avenue. The American Pharmacists Association-Academy of Student Pharmacists at UTHSC is partnering with Fred's to provide free blood pressure screenings through Feb. 28.
Even though the official grand opening isn't until May, one Crosstown Concourse tenant is already up and running.
NASHVILLE – The unveiling of legislation undercutting same-sex marriage and enforcing transgender bathroom rules turned into a short-circuited press conference and confrontation Wednesday, Feb. 15.
NASHVILLE, Tenn. (AP) – Tennessee Republican legislative leaders are suggesting stricter security to enter the Capitol complex after a few dozen protesters interrupted a news conference about transgender bathroom access.
NASHVILLE, Tenn. (AP) – Reagan administration economist Arthur Laffer is urging Tennessee lawmakers not to include a cut in the sales tax on groceries as part of Republican Gov. Bill Haslam's proposal to offset a gas tax hike.
After he had answered the obligatory questions about the Grizzlies' ugly 95-91 loss to the New Orleans Pelicans in the last game before the All-Star break, coach David Fizdale spoke to the big picture: "We're in good position."
Todd Helton stands behind the batting cage at Tennessee's Lindsey Nelson Stadium, eyeing swings and chatting with UT baseball players.
Upon his arrival as the Tennessee Titans' general manager in January 2016, Jon Robinson made an immediate impact with the trade for DeMarco Murray and his wheeling/dealing approach to the draft.
There are a lot of ways to define the state of men's professional tennis, but maybe the easiest is to open up the 2017 ATP World Tour Media Guide and turn to the alphabetical listing of players. Let's try the "K" section.
Erica Murrell admits to three obsessions: kids, animals and science. Fortunately, she's got a job that connects all three. "For me, it's about connecting people with what they're passionate about," she says. "I love figuring out where to put them."
WHEN PUBLIC GOES PRIVATE, WE HAVE IT BACKWARDS. My kids and I know more about public schools and public school innovation than our brand-new secretary of education and voucher poster girl, Betsy DeVos, and our own state senator and voucher poster boy, Brian Kelsey.
Ray's Take How much you spend from your retirement savings from year to year is arguably the most important piece in the retirement finance puzzle.
NASHVILLE, Tenn. (AP) – The largest U.S. private prison operator has rejected a shareholder resolution seeking independent audits of its detention facilities.
LITTLE ROCK, Ark. (AP) – The Arkansas House has approved cuts to the state's unemployment benefits as part of a bill that also reduces taxes on employers.
SAN FRANCISCO (AP) – President Donald Trump's administration said in court documents on Thursday it does not want a larger appellate panel to review a ruling keeping its travel ban on hold and will instead replace the ban.
NEW YORK (AP) – Freddie Mac said Thursday that it will pay the U.S. Treasury a dividend of $4.5 billion next month after its profit more than doubled in the last quarter.
PHILADELPHIA (AP) – The heart of Philadelphia's Italian Market was uncommonly quiet. Fine restaurants in the nation's capital and New York closed for the day. Grocery stores, food trucks, coffee shops and taco joints in places like Chicago, Los Angeles and Boston shut down.
DETROIT (AP) – The United Auto Workers union is preparing an ad campaign that urges people to buy U.S.-made vehicles as it tries to tap into feelings of nationalism stoked by President Donald Trump's election.
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Uganda holidays
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Accommodation rating: Superior
Please call 020 7873 5000 for more information or to make a booking.
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Located on Buziga Hill, one of the highest hills in Kampala, the Cassia Lodge offers...
Le Petit Village is located 10 minutes from the city centre of Kampala in the heart of...


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Have you ever keeping upped too late merely because your bed did not seem really welcoming? Is the bed linen in your dreams a lot better than the place where you do the dreaming? A comfy bed is easier to have than you may anticipate. Using the perfect pieces, you can make your bed linen more welcoming– so you will be thrilled to visit bed.
Welcoming Bed linen and Accessories:
one. Ornamental pillows make any bed welcoming. three or four toss pillows seem to say, "welcome to bed." Consist of a couple of accent pillows that tie into the design of your comforter or duvet. The color and the depth created by layering pillows will consist of style and a look of comfort to your bed. Consider care not to overdo it, nonetheless; a great deal of accent pillows will say "there's no room for you."
two. Mattress toppers improve comfort in an instant. Whether or not you just need a little extra cushioning on the firm mattress otherwise you have to lengthen the lifestyle of your mattress, you will love what a mattress topper can do for you. Side sleepers will particularly worth extra gentleness from a topper. A down featherbed includes rippling high-end to your bed, whilst a memory foam mattress topper can consist of a little more help.
three. A toss blanket will help you feel comfy. Whether or not folded nicely in the foot of the bed or curtained delicately across one corner, a toss blanket is outstanding at encouraging you to rest. Use it for naps or pull it up as an extra layer on cold nights. In the event you need an excellent deal of convincing that it is time to visit bed, search for something that is made from a luxuriously soft item, like cashmere or synthetic fur, and you may discover that you keep moving your bedtime previously and previously.
four. Bed linen accessories can help with special needs. In the event you need something extra in order to sleep nicely, don't depart it off your bed merely because it is unusual. Specialized pillows in particular help lots of people get a lot better night's rest. In the event you get up with pains in your back, you may need a body pillow or perhaps a particularly contoured neck pillow. If you are pregnant, you may need a pillow that can support your stomach or hips. In the event you have to sleep with oxygen, you would be happier with a pillow made to accommodate your mask. In the event you have substantial allergic reactions, you may have to use a pillow protector. Whatever your needs are, there are memory foam bed linen accessories to help you rest nicely. Once you have them, you will anticipate going to sleep.
Make Your Bed Comfy:
– Ensure Tidiness
Refurbishing your item thanks to mattress-inquirer research will help you sleep a lot better because you will rid it of dust, allergen, and wetness. Vacuum the mattress totally, using an accessory if needed.
– Use a mattress Topper
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Four children in Arizona are sickened with E. coli O157 infections that "appear to be linked" to soynut butter-containing products from "The SoyNutButter Company," according to a news release from the Arizona Department of Health. The Arizona Department of Health Services is recommending that consumers avoid eating "I.M. Healthy" brand soynut butter and soynut butter-containing products. Dr. Cara Crist, director of the department, said in a statement, "Our disease detectives are working on the state and local level to rapidly identify the source of this outbreak. As we determine suspected food sources that may be linked to E. coli, our state lab will test those products to determine if there's a match." The four children who are sick in Arizona live in Maricopa and Coconino … [Read more...]
Four Arizona Children Sickened with E. coli O157
Salmonella outbreak linked to JEM Nut Butter Spreads
A Salmonella outbreak has been linked to nut butter spreads produced by JEM Raw Chocolate of Bend, Oregon. At least 11 people have been sickened. The company is recalling its full line of nut butter spreads which are packaged in glass jars, and sold under brand name JEM Raw Organics. They were distributed nationwide in retail stores and through mail order between June 2015 and November 2015. Consumers who have purchased these products should not eat them as Salmonella can cause serious illness and death. The recalled products include: 1 oz sizes of: Cashew Cardamom - Sprouted Cashew Almond Spread with UPC 6 09728 97861 7; Cinnamon Red Maca - Sprouted Almond Spread with UPC 6 09728 97862 4; Hazelnut Raw Cacao - Sprouted Hazelnut Spread with UPC 6 09728 97865 5; Superberry Maqui Camu … [Read more...]