text:
I was so surprise that kixeye suspended my account after i bought gold from them, for the past one year i have spend more than $1000 from this game (war commander), they can't provide me how my account was suspend, they are a cheat company, i would like them to refund me back my money, or unsuspended my account, this is a cheat company that cheat all my money.
they should stated why i'm suspended, anyway i would like them to refund my money back after i have spend so much on that cheating company game,i'm so pissed that they are not fair to every players, they engage their own employee that cheat and force us to buy gold from them, their team members clan called as (KT)
Review about: Kixeye Account.
Monetary Loss: $2000.
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text: Black magic is the very effective way to solve your problems quickly and even more effective way. But it also causes harmful effect if you use this black magic by your own. Our Black Magic Specialist in Washington DC (USA) has a several years' experience and millions of customers are satisfied. Call Now for Immediate Solution.

subset: commoncrawl


text:
June 19, 2017
| Article
Summer is upon us and that means pedicure appointments are filling up as clients prepare to shed their shoes in favor of flip-flops and sandals. Make sure your clients' heels are healthy and smooth so they dare to be bare. These five treatments will fight dry skin and give your clients beautiful, beach-ready feet.
January 3, 2017
| Article
Beautification is our business, but what happens when a new client reluctantly reveals feet that appear to defy even our considerable skills? Learn how to talk clients out of their embarrassment and into a regular foot maintenance program.
June 5, 2015
| Product
Invented by a nurse, Happy Feet and Body Formula TX is a two-part system that works to relax, soothe, hydrate, and reduce aches and swelling by improving circulation.
December 29, 2014
| Product
Cuccio Naturalé's Professional Pedicure Hydrating Heel Treatment contains both organic argan and urea, imparting intense hydration for extremely dry skin.
May 1, 2014
| Article
Pedix Feet is a new complete foot and leg care line by Alessandro featuring the MarinaVital complex, which contains spirulina algae, proteins, amino acids, enzymes, vitamins, sea salts, essential oils, and plant extracts.
March 18, 2014
| Product
Alessandro's Pedix Feet Heel Smoothing Stick is the ideal treatment for targeted relief of dry, cracked heels.
September 13, 2013
| Video
Treating cracked, callused, and dry skin is an important element of any pedicure. Gehwol recommends products and techniques for the service as well as follow-up or at-home care.
August 21, 2012
| Article
To repair dry, cracked, and fissured heels, podiatrist Bill Danzeisen swears by Barefoot Botánica's Cracked Heel Repair Creme and Pomegranate Sugar & Shea Scrub, products he custom formulated for his clients.
June 27, 2012
| Article
New York City-based podiatrist Dr. Krista Archer has launched her own line of ARCH skin products, which use natural ingredients to heal and moisturize dry, cracked feet and protect the nails.
March 8, 2012
| Video
Foot care company Gehwol shares how to use its products to heal clients' heel cracks, callus, and dry skin conditions.
January 31, 2011
| Product
For problem feet, Nailology offers its best-selling Crack No More Heel Cream.
December 15, 2010
| Product
Sole Mate helps dissolve and soften thick calluses and fight foot bacteria.
January 1, 2010
| Product
Called the "sole soother", this heel cream comes in a handy stick and can also be used on rough knees and elbows.
December 29, 2009
| Product
Xenna Corporation's CalleX Ointment thins and softens hardened skin and exfoliates dry, cracked heels.
June 1, 2008
| Product
Pedi-Sox now has a Softening & Conditioning Foot Cream to work in conjunction with the Pedi-Sox brand pedicure sock.
Eye-Catching Acrylic Powders14 photos
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text: In 2006, students at Austin High School in Austin, Minnesota engineered a prank that capitalized on the unusual architecture of their school. A busy street separates two buildings on the school's campus. Students can use the crosswalk or an underground tunnel to get from one building to the other. At an appointed time on the day of the prank, 94 students began filing across the street, using the crosswalk. Then they circled back through the underground tunnel and crossed the street again—and again, and again—creating an endless stream of pedestrians. Traffic was tied up for nearly 10 minutes as cars lined up waiting for the students (including one dressed as a cow and another as a chicken) to finish crossing.


text:
Blacklight: Retribution made major waves when it launched on PC in early 2012. Free-to-play is everywhere now, but at that time a gorgeous, fast-paced first person shooter was not the experience most gamers pictured when they imagined a free game download.
In the 18 months since, free-to-play has become much more common. But Blacklight's fast-paced, Call of Duty-esque action and clever sci-fi gameplay twists allowed the game to keep its loyal player base. IGN awarded it an 8.5/10 for a reason, after all.
And now that Blacklight is available on the PS4, console gamers now have the opportunity to jump in as well. But where to start? Is Blacklight a freemium trap, or is it truly possible to have a fun, spending-free experience? Let's take a look.
How free is it?
At a glance Blacklight's store and unlock systems seem just like every other freemium game. As you level up you unlock new guns and equipment which you can buy with in-game currency.
Blacklight's major tweak to this formula is that you can also rent items for a day or a week. It's a fairly generous system, especially if you're committed to playing at least a little while with your rented equipment before it expires. Play just a handful of matches and you'll earn back the game points you spent renting equipment for the day. This lets you try out a variety of loadouts and weapon types relatively risk-free without dropping major dough - or any dough at all, really. You can rent a sniper rifle one day and a shotgun the next to get a feel for which you like most.
The catch to this relatively forgiving rental system is twofold. First, buying an item outright, so that you always have access to it and don't have to keep renting, is often extremely expensive. More on this in a bit.
Second, although almost every item in the game can be earned by non-paying players willing to grind, any item purchased with premium currency bypasses the level requirement. So non-paying players will need to wait until level 20 to unlock badass abilities like Cloak, while paying players can jump right in and purchase it, along with any other item, regardless of their requirements.
This means there won't be an army of super-powered super-soldiers mowing down second class citizen free players with all their inaccessible exclusive gear, but if you intend to play for free you might begin to resent the grind.
If you buy just one thing…
Like Call of Duty, a kitted-out, max-level Blacklight player can often wipe the floor with you thanks to their perfectly tuned loadout. But also like Call of Duty, your basic starter assault rifle, available from level 1, is more than capable of dishing out plenty of punishment of your own. Especially if you get the drop on an enemy. So when you first jump into Blacklight, enjoy getting a feel for the maps, the controls, and the unique multiplayer experience Zombie Studios has crafted. As you earn some GP feel free to spend it on one-day rentals so you can get some experience with different scopes, barrels, weapon types, and more.
Eventually you should get a pretty good feel for what kind of play style suits you most. Stealthy cloaked sniper? Up close and personal pistol user? Once you've made up your mind, it's probably a good time to plunk down some dough.
Instead of spending GP to rent all the parts needed for your favorite loadout each day, they can be permanently purchased real real-world money. It isn't cheap, though. Each of the individual parts might run you $5 or more, and you might need several to complete your desired setup. Realistically you might need to drop $30 to customize your class, but this amount can be higher or lower depending on specifics.
This might seem expensive, but by this point in your Blacklight career the game's flexible rental system should have already given you a good idea of what items are best for you to spend your money on, and you should have already put in enough hours to know you want to spend any at all.
What can you spend if you get addicted?
Unfortunately Blacklight: Retribution is not the kind of game where OCD gamers will be able to easily own everything. With individual gun parts and items often running $5 or more, and with hundreds of attachments available, a truly hooked gamer could easily spend thousands of dollars. That's an extreme example, but $100+ for a dedicated player is within the realm of possibility.
On the flipside, almost everything can also be permanently unlocked with earned currency - albeit a whole lot of it. About 5,000 games played will give you enough currency to unlock most items in the game. It's a crazy-high number, but plenty of Call of Duty and Halo players put in far more than that without breaking a sweat.
Justin Davis is the second or third best-looking Editor at IGN. You can follow him on Twitter at @ErrorJustin and on IGN.


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|JUSTIN BIEBER with a fan. And she seems a little standoffish so I'm just going to assume he spit on her.
Anyway, our boy is at this very moment onstage at the ACC whipping the tweens into a frenzy of hormones (I mean those poor girls' faces are going to break out like they've never broken out tomorrow), and he apparently got there without doing anything more scandalous than lobbing a gob off his Yorkville hotel balcony. Which, considering his behaviour lately is practically a miracle, yet which was nevertheless enough to send TMZ into an all-caps frenzy: "JUSTIN BIEBER SPITTING AGAIN, Caught in the act!" (You can see the pics here, and man are they attractive. He practically looks like royalty.)
Uh, dudes. If Biebs is in town and something wet drops out of the sky onto your head and it turns out to be just spit, that's a good thing.
Editor's Note: Although I have to say I haven't written disaster off just yet. Because he's brought his moronic Svengali Lil


text:
Big Knit Scarf
Product Code: SALE_BKTCS
£45.00 was £85.00
Select a colour:
Select a size: Size Guide
Product description
A look-twice splash of colour. An enveloping whisper of warmth. Drape it on and you're ready to face the world.
100% cashmere
Size 170x70cm (67"x27.5")
100% cashmere
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text:
The Hill: Warrior candidates not yet battle-hardened, Dems worry
from The Hill:
Hackett stumbled in early September, Democrats add, when he failed to announce his bid to unseat Sen. Mike DeWine (R-Ohio) sooner instead of later, inviting a challenge from Rep. Sherrod Brown (D). Now the party faces a protracted primary.
What? That sure isn't how I remember it going down. I coulda swore it was Brown who delayed. Coulda swore. What kind of revisionist history is this? So now Hackett is the reason for a contested primary? I seem to remember he got there first and Brown said he felt the people of the 13th still needed him.
this blog isn't bullshit
Hackett "stumbled" by not announcing during the worst natural disaster in the history of the country (which drenched Ohio)?
I think the only mistake Hackett made was trusting Sherrod Brown. MTB made the same mistake by trusting that Sherrod Brown would keep his committment. Let's hope that the voters won't set themselves up to get burned by putting faith in somebody as untrustworthy as Brown.
Paul was being careful to make sure that he had the support of the leadership in Washington. Paul's crazy that way. He likes to be a good team player. Little did he know that the rats in DC were already trying to screw him. Lies from that trip came out the same day in the press.
Hackett stumbled?
Even if Hackett had announced in September, Sherrod Brown would STILL hve announced later because Hackett had ALREADY TOLD BROWN THAT HE WAS GOING TO RUN AFTER HE GOT BROWN'S OKAY THAT Brown WASN'T GOINT TO RUN. It was Strickland who convinced Sherrod to finally enter the Senate race. This had nothing to do with Hackett.
Reporters are so stupid.


text:
No shortage of gluten in Paris, where there seems to be a boulangerie on almost every block. Piled atop a counter, freshly baked plump brioches are the special of the day.
15 April 2015
Gluten rules
Labels: boulangerie , boulangeries , breads , brioches , gluten , special of the day
Posted by Barbara Pasquet James
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text:
Fund Established To Help Daughter Of Drunken Driving Victim
Fund Established To Help Daughter Of Drunken Driving Victim
LOUISVILLE, Ky. —
A fund has been established to help the daughter of a woman killed by a drunken driver.
Sherrie Dulin, 48, died last Thursday, three days after she was hit while crossing the street at National Turnpike and Outer Loop.
Police said Heidi Diaz hit Dulin in the crosswalk. According to police, Diazs blood alcohol level was nearly twice the legal limit and she didnt have a drivers license.
Donations can be made at any Republic Bank to the Paige Miller Support Fund.
Miller, Dulins daughter, is a junior at Atherton High School.
Miller is also a member of the Louisville Youth Philanthropy Council, which gives grants to help out the community.


text:
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text:
Hirschsprung's disease, Light micrograph
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text:
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The Universal Connector infrastructure records data provenance throughout any ISL/CHAIN-enabled analytic workflow. Provenance tracking is started immediately upon data receipt. Provenance is recorded in detailed terms, such as data source, data record, unique personal identifiers (e.g., passport numbers, drivers licenses numbers), and the relationships between identifiers common to multiple records..
The information explosion over the past decade has shifted the focus from gathering data to creating knowledge. Global InfoTek provides our customers with knowledge creation solutions, from semantic understanding of data to user controlled orchestration and workflow
Global InfoTek researches, designs, develops, and scientifically evaluates intelligent software applications using a broad range of state-of-the-art knowledge intensive techniques. Global InfoTek strives to solve customer's hard problems by using the best state of the art techniques and building on the latest research for scalable and deployable technologies.
Global InfoTek, Inc. provides experienced staff to conduct scientific test and evaluation of emerging technologies for its customers. Our staff works closely with program managers from concept definition to post experiment analysis to ensure unbiased technical assessment of complex information systems. Global InfoTek, Inc. has supported numerous test and evaluation efforts during the past twenty years. Our experience enables us to offer proven strategies for scientific accomplishments and attainment of program objectives.
Depending on the program's needs, Global InfoTek typically provides the following services:
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As a test and evaluation performer Global InfoTek often helps to focus and accelerate the pace of research projects by developing a clear, program-wide system concept that fosters the research and development of representations and artifacts needed for interaction across program areas.


text:
From 01/08/2018 To
* From To
This garment passed a 60L/m²/hr shower test lasting 1hr. This test replicates the average conditions of a rain shower.
This jacket's fabric is water repellent: this is its capacity to make water run off its surface without absorbing it. It prevents the fabric from soaking up water and keeps it lightweight and breathable. A fabric becomes water repellent by applying a treatment to its outer surface.
What's more, the main seams that are most exposed to the rain are taped.
The fabric's water repellent properties must be reactivated in order to preserve long-lasting effective waterproofing: we recommend that this is done every 3 washes or after wearing a dozen times in the rain. After washing, the garment must be thoroughly rinsed, after which the water repellent properties can be easily reactivated by warming: for a short period of time in a tumble dryer or with a hair-dryer, for example. You will find all our tips in the maintenance manual of this product sheet.
Raincut over-trousers for protecting the lower body as well, so that you can have a complete outfit that offers highly effective protection against wind and showers.
We measure a fabric's capacity to support a column of water expressed in mm (based on the ISO 811 standard). The higher the water pressure, the more waterproof the fabric. A component with a waterproof rating of 2000 mm means that the fabric can withstand the pressure exerted by a 2000 mm column of water
To find out whether a fabric is breathable, we test its evaporative resistance or RET (based on the ISO 11092 standard). The lower the fabric's resistance, the more water vapour generated by physical activity evaporates, and the higher the fabric's breathability. For example: RET < 9 = extremely breathable fabric / 9 < RET < 12 = very breathable fabric / 12 < RET < 20 = breathable fabric / RET > 20 = fabric is not breathable or has low breathability.
The environmental impact of the product is calculated over its entire life cycle using different indicators. An overall rating of ABCDE is provided to help you easily identify products with the best environmental performance by comparing products of the same type with each other (t-shirts, trousers and backpacks). Decathlon is a voluntary participant in this environmental labelling initiative. For further information: http://sustainability.decathlon.com/
2XS: 0.22 kg
XS: 0.22 kg
S: 0.22 kg
M: 0.22 kg
L: 0.22 kg
XL: 0.22 kg
2XL: 0.22 kg


text:
As a business consultant, advisor or coach, your success is as closely tied to the success of your clients as ours is. Worldwide101 provides high quality virtual business services to growing small businesses. From administrative support to customer service, from marketing to book-keeping, we help cover key functions so that business owners can stay focused on the strategic priorities. When you recommend Worldwide101 to your clients, you are giving them access to a valuable resource for their business growth, and an industry-leading team with a 100% quality guarantee.
Copyright © 2015 Worldwide 101 Ltd


text:
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This year resesrch shows that approximately 85% of all Web sites are found via search engines
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In the field of SEO, link building describes actions aimed at increasing the number and quality of inbound links to a webpage
Our SEO review consists of several factors like a content, linking structure, social media efforts, and its trust on the internet
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text:
The Des Moines Science Fiction Society (DMSFS) is a 501(c)(7) organization that seeks to work cooperatively with local individuals, organizations, and media to promote a variety of causes, including: scientific research, space exploration, literacy, and the arts. Basically, we are a gathering of central Iowa science fiction, fantasy and gaming fans. Our interests include reading science fiction and fantasy (of course), watching science fiction and fantasy (of course), cutting-edge science and technology (of course), playing games (of course), the space program (of… you get the idea), computers, F&SF gaming, alternative philosophies and faiths such as neo-paganism, cyberpunk, overdressing, under-dressing, and many, many, many other cool things.
Persons seeking information on science, science-fiction, or fantasy-related topics, and organizations looking for additional resources (including volunteers) for similarly-related activities, are invited to contact any club officer or member at email@example.com.
DMSFS is the sponsor of DemiCon, Des Moines' annual science fiction, fantasy and gaming convention. But we do other things, too. Like getting together twice a month to discuss science fiction stuff. Go to a monthly movie. Hosting DemiCon Lites to learn awesome things and supporting the community like knitting, computer security, listening to live music, costuming, walking for a cause, and the list goes on. Also for throwing some bodacious parties (oops — excuse me; I meant, "gathering for the semiannual DMSFS constitutional conventions"). And most essentially like enjoying the company of others that share our interests.
DMSFS currently meets the second and fourth Fridays of each month at the Valley Junction Activity Center at 217 4th Street. It is 2 doors north of the Tavern Restaurant in the Valley Junction district. There is a parking lot off of the 4th Street side of the building with plenty of room. The building is a 2 story sandstone building with burgundy awnings and trim. We meet in the lower level large room.
Membership in the DMSFS is open to anyone and everyone (really — it says so in our bylaws). There are no dues or membership fees. No goofy hazing rituals (well… maybe we'll "smooth" you, if you've never been smoothed before. But only if you want to). Our current members include high school students and senior citizens; doctors, landlords, business owners, computer geeks, and mimes; readers, writers, media fans, gamers, and people with real lives. In short, folks from all walks of life.
If you live in, or even just occasionally visit, the Des Moines area, then for heaven's sake, join us! Meetings are typically held on the second and fourth Fridays of each month. Exact details for the next meeting can be found on our calendar/event page. If you have any questions concerning DMSFS, please e-mail us at email@example.com.
Now that you know all this, you no longer have an excuse not to at least stop by once in a while to say, "Hi." We'd appreciate the opportunity to meet you and find out who you are.


text:
simpleSAMLphp login
User login
Google kereső
Cell Biology group
Head of the group:
Gábor Szabó
Full Professor
E-mail: szabogmed.unideb.hu
www: rcmm.dote.hu/research-groups/cell-biology/
Gábor Szabó, M. D., Ph. D., D. Sc.
Katalin Goda, Ph. D.
Éva Hegedűs, Ph. D.
László Imre, M. Sc., Ph.D. student
Gábor Szalóki, M. Sc., Ph.D. student
Szabolcs Tarapcsák, M. Sc., Ph.D. student
Péter Nánási, M. D., Ph.D. student
Erfaneh Firouzi Niaki, Dr. Pharm., Ph.D. student
Adél Nagy Vezendiné, laboratory assistant
Tamás Varga, Ph.D.
Henrietta Nagy, Ph.D.
Zsolt Bacsó, M.D., Ph.D.
Ferenc Fenyvesi, Ph.D.
Orsolya Bársony, Ph. D student
Zsuzsa Tóth, Ph. D. student
György Fenyőfalvi, M. D.
Gyöngyi Dajka, laboratory assistant
Annamária Téglási, laboratory assistant
Lóránt Székvölgyi, Ph.D.
We are interested in the mechanistic and molecular relationships between catalytic activity, conformational changes and microenvironment of ABC transporters. P-glycoprotein (ABCB1, Pgp) is in the focus of our interest; we have currently extended our work to ABCG2 (BCRP) and plan to do similar studies on MRP1 (ABCC1). The members of the ABC superfamily of membrane transporters are involved in the regulation of the uptake into and distribution within our body of physiological substrates as well as various xenobiotics, drugs. Due to their wide substrate spectrum, a consequence of their preference for lipophylic compounds, they also play a critical role in the multidrug resistance phenomenon severely limiting therapeutical success in cancer. Our ambition is to understand the molecular details of their catalytic cycle and the intimate molecular interactions with their microenvironment, as well as to apply the knowledge obtained at the cell/molecule level in the context of the whole organism, in vivo.
Our experimental approaches include: (a) sensitive flow-cytometric methods to detect substrate efflux; (b) ATPase assays to measure the interaction of drugs with ABC transporters in membrane fractions; (c) intracellular ATP concentration measurements in live cells using a FRET-based intracellular ATP sensor; (d) a flow-cytometric platform for the measurement of raft- and cytoskeleton-association of cell-surface proteins, applicable also for rapid, simple, serial analysis of intermolecular associations between different cell surface proteins; (e) immunoprecipitation and co-immunprecipitation to study protein-protein interactions by Western-blot and MALDI analysis; (f) a sensitive flow cytometric assay to measure ATP dependent conformational changes of Pgp and ABCG2 in Staphylococcus toxin permeabilized cells; (g) a confocal microscopic assay to measure substrate binding to transporters in live as well as permeabilized cells; (h) xenotransplantation system in SCID mice to study the effect of ABC transporter modulators on multidrug resistant tumors by PET.
Publications (last 10 years):
1. Szalóki G., Krasznai ZT., Tóth Á., Vízkeleti L., Szöllősi AG, Trencsényi Gy, Lajtos I., Juhász IJ, Krasznai Z., Márián T., Balázs M., Szabó G., Goda K.: "The strong in vivo anti-tumor effect of the UIC2 monoclonal antibody is the combined result of Pgp inhibition and antibody dependent cell-mediated cytotoxicity. PLOS ONE 9 (9): e107875. 2014, IF: 3.534 (2013)
2. Krasznai ZT, Trencsenyi G, Krasznai Z, Mikecz P, Nizsaloczki E, Szaloki G, Szabo JP, Balkay L, Marian T, Goda K: 18FDG a PET tumor diagnostic tracer is not a substrate of the ABC transporter P-glycoprotein. European Journal of Pharmaceutical Sciences 64: 1-8, 2014, IF: 3.005 (2013)
3. Trencsényi Gy., Márián T., Lajtos I., Krasznai Z, Balkay L., Emri M., Mikecz P., Goda K., Szalóki G., Juhász I., Németh E., Miklovicz T, Szabó G., Krasznai ZT. "18FDG, [18F]FLT, [18F]FAZA and 11C-methionine are suitable tracers for the diagnosis and in vivo follow up the efficacy of chemotherapy by miniPET both in multidrug resistant and sensitive human gynecologic tumor xenografts" BioMed Research International, Volume 2014, Article ID 787365, IF:2.706 (2013)
4. Fenyvesi F, Réti-Nagy K, Bacsó Z, Gutay-Tóth Z, Malanga M, Fenyvesi É, Szente L, Váradi J, Ujhelyi Z, Fehér P, Szabó G, Vecsernyés M, Bácskay I. Fluorescently labeled methyl-beta-cyclodextrin enters intestinal epithelial Caco-2 cells by fluid-phase endocytosis. PLoS One. 2014 Jan 8;9(1):e84856.
5. Goda K, Szaloki G: "A sensitive tool to measure CFTR channel activity." 2013. Cytometry A. 83(6), pp. 528-529. IF: 3.066
6. Telbisz A; Hegedus C; Ozvegy-Laczka C; Goda K; Varady G; Takats Z; Szabo E; Sorrentino BP; Varadi A; Sarkadi B: Antibody binding shift assay for rapid screening of drug interactions with the human ABCG2 multidrug transporter. EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES 45: 101-109, 2012, IF: 2.987
7. Krasznai, Z.T., Tóth, Á., Mikecz, P., Fodor, Z., Szabó, G., Galuska, L., Hernádi, Z., Goda, K.: Pgp inhibition by UIC2 antibody can be followed in vitro by using tumor-diagnostic radiotracers, 99mTc-MIBI and 18FDG. Eur. J. Pharm. Sci. 41:665-669, 2010. IF:3.291
8. Goda K, Bacsó Zs, Szabó G. Multidrug resistance through the spectacle of P-glycoprotein (review) Current Cancer Drug Targets, 9:281-97, 2009. Review IF:5.129
9. Özvegy-Laczka, C., Laczkó, R., Hegedűs, C., Litman, T., Várady, G., Goda, K., Hegedűs, T., Dokholyan, N.V., Sorrentino, B.P., Váradi, A., Sarkadi, B.: Interaction with the 5D3 Monoclonal Antibody Is Regulated by Intramolecular Rearrangements but Not by Covalent Dimer Formation of the Human ABCG2 Multidrug Transporter. J. Biol. Chem. 283 (38), 26059-26070, 2008. IF:5.52
10. Fenyvesi, F., Fenyvesi, É., Szente, L., Goda, K., Bacsó, Z., Bácskay, I., Váradi, J., Kiss, T., Molnár, É., Janáky, T., Szabó, G., Vecsernyés, M.: P-glycoprotein inhibition by membrane cholesterol modulation. Eur. J. Pharm. Sci. 34 (4-5), 236-242, 2008. IF:3.65
11. Goda K, Fenyvesi F, Bacsó Z, Nagy H, Márián T, Megyeri A, Krasznai Z, Juhász I, Vecsernyés M, Szabó G Jr. Complete inhibition of P-glycoprotein by simultaneous treatment with a distinct class of modulators and the UIC2 monoclonal antibody. J Pharmacol Exp Ther. 320:81-8. 2007. IF:4.003
Nuclear organization and chromatin structure group - Superhelical and relaxed chromatin domains
Due to the repressive nature of nucleosomes, the main underlying scheme of gene regulation in eukaryotic cells is de-repression. On the other hand, nucleosome stability is highly sensitive to the degree of superhelicity, a transcription dependent feature of the matrix anchored DNA loops. However, at their anchorage points, genomic DNA is relaxed due to strand discontinuities arising in conjunction with transcription, likely introduced by topoisomerase enzymes. We are investigating the molecular determinants and dynamic features of these two distinct chromatin domains in the context of gene activition. Our ambition is to unravel the complex relationships between nucleosome stability and organization of superhelical chromatin loops, and understand the relationships between the organizational principles seen at the loop level and those of global nuclear compartmentalization.
Our experimental systems include mammalian cells, mouse embryonic stem cells and S. cerevisiae, studied by (a) confocal microscopic analysis of the localisation patterns of free 3'OHs detected by in situ nick translation or terminal transferase reaction relative to those of transcription related R-loops (RNA/DNA-hybrids), topoisomerase enzymes and epigenetic marks (PTMs); (b) a laser scanning cytometric (LSC) assay of nucleosome stability, measured in a PTM and cell cycle dependent manner; (c) an LSC assay of superhelical density and size distribution of loops; (d) molecular combing of DNA; (e,f) various gelelectrophoretic techniques (denaturing urea-agarose, CHEF), including single-cell electrophoresis of large DNA molecules; (g) a reverse South-Western blotting technique to map strand breaks and R-loops and (h) standard genomic techniques (microarray,chip seq).
Publications (last 10 years):
1. Szekvolgyi L, Ohta K, Nicolas A. Initiation of meiotic homologous recombination: flexibility, impact of histone modifications and chromatin remodeling. CSH PERSPECT BIOL (2015)
2. Acquaviva L*, Szekvolgyi L*, Dichtl B, Dichtl BS, Saint Andre CD, Nicolas A, Géli V. The COMPASS Subunit Spp1 Links Histone Methylation to Initiation of Meiotic Recombination. Science 339(6116): 215-218.
*joint first-authors
3. Imre L, Balogh I, Kappelmayer J, Szabó M, Melegh B, Wanker E, Szabó G. Detection of mutations by flow cytometric melting point analysis of PCR products. Cytometry A. 2011 Sep;79(9):720-6. doi: 10.1002/cyto.a.21104. Epub 2011 Jul 19. PubMed PMID: 21774077.
4. Hegedüs E, Kókai E, Kotlyar A, Dombrádi V, Szabó G. Separation of 1-23-kb complementary DNA strands by urea-agarose gel electrophoresis. Nucleic Acids Res. 2009 Sep;37(17):e112. doi: 10.1093/nar/gkp539. Epub 2009 Jun 23. PubMed PMID: 19553189; PubMed Central PMCID: PMC2761254.
5. Hegedüs E, Imre L, Pataki J, Lizanecz E, Székvölgyi L, Fazakas F, Bacsó Z, Tóth A, Szabó M, Seres Z, Szabó G. Heteroduplex analysis using flow cytometric microbead assays to detect deletions, insertions, and single-strand lesions. Cytometry A. 2008 Mar;73(3):238-45. doi: 10.1002/cyto.a.20492. PubMed PMID: 18205197.
6. Székvölgyi L, Rákosy Z, Bálint BL, Kókai E, Imre L, Vereb G, Bacsó Z, Goda K, Varga S, Balázs M, Dombrádi V, Nagy L, Szabó G. Ribonucleoprotein-masked nicks at 50-kbp intervals in the eukaryotic genomic DNA. Proc Natl Acad Sci U S A. 2007 Sep 18;104(38):14964-9. Epub 2007 Sep 11. PubMed PMID: 17848525; PubMed Central PMCID: PMC1986596.
7. Székvölgyi L, Bálint BL, Imre L, Goda K, Szabó M, Nagy L, Szabó G. Chip-on-beads: flow-cytometric evaluation of chromatin immunoprecipitation. Cytometry A. 2006 Oct 1;69(10):1086-91. PubMed PMID: 16998871.
8. Székvölgyi L, Hegedüs E, Molnár M, Bacsó Z, Szarka K, Beck Z, Dombrádi V, Austin C, Szabó G. Nick-forming sequences may be involved in the organization of eukaryotic chromatin into approximately 50 kbp loops. Histochem Cell Biol. 2006 Jan;125(1-2):63-73. Epub 2005 Sep 30. PubMed PMID: 16195888.
9. Pataki J, Szabó M, Lantos E, Székvölgyi L, Molnár M, Hegedüs E, Bacsó Z, Kappelmayer J, Lustyik G, Szabó G. Biological microbeads for flow-cytometric immunoassays, enzyme titrations, and quantitative PCR. Cytometry A. 2005 Nov;68(1):45-52. PubMed PMID: 16163684.


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HK radicals: how independence movements start
From America to India, history is littered with examples of how separatist movements are born out of a sense of frustration with the status quo. Is there a lesson to be learned for Hong Kong?
What are the historical processes that radicalise individuals hitherto prepared to work incrementally within established political frameworks, turning them resolutely towards sweeping change? Many leaders of what would become independence movements often, subsequent heads of new nation-states did not initially aim for full political separation from their erstwhile sovereign power. Most simply wanted a desire for reasonable political change to be met sympathetically, intelligently and constructively by those in power. History offers numerous examples of the independence genie once released adamantly refusing to go back in the bottle.
In the early 1770s, George Washington, Thomas Jefferson and their associates in Britain's North American colonies initially sought better representation for their local interests in London, and a more responsive home-grown government. And that was all. These individuals radicalised into separatism leading ultimately to the American revolution and a new independent state only when requests for improved governance on local issues were repeatedly, arrogantly ignored by a faraway, poorly advised government badly served on the spot by its own appointees.
On the winding path towards Indian independence, from early constitutional reforms in 1917 to the government of India Act in 1935, which paved the way for autonomy, any slow down was, rightly or wrongly, interpreted by Indian nationalists as a sign of poor faith by Britain. Venal, incompetent local politicians who like crabs in a bucket were usually more interested in pulling each other down than climbing out of the pot, didn't help matters; the few genuine statesmen among them, such as Jawaharlal Nehru, had their work cut out to maintain the forward momentum that finally brought independence in 1947.
In 1946, following Sukarno's August 1945 declaration of independence from the Dutch, Indonesian nationalist leaders signed the Linggadjati Agreement. This accord would recognise an independent Indonesia with close association with the Netherlands, along similar lines to the relationships between Britain and Australia, New Zealand, Canada and South Africa.
Almost immediately, this compromise was unilaterally altered by the Dutch government, rendering it practically unworkable and politically impossible for even the most moderate Indonesian nationalists to accept. The Dutch went on, over the next decade, to lose literally everything they possessed in Indonesia as a direct consequence.
In Hong Kong, essential reform has been repeatedly stalled since the 1997 handover. Across the political spectrum, no one with any credibility continues to publicly pretend that all is well, that the Hong Kong people are fundamentally apolitical and only interested in making money, and that every other reassuring bromide from the past still retains any relevance.
Widespread youth mobilisation is the most striking new development; the sheer number of articulate, motivated 20-somethings who ran for public office in the 2016 Legislative Council election or attempted to do so, until prevented is unprecedented.
When one side of a political reform process feels it has been unreasonably obstructed, serially hoodwinked, generally led up the garden path and yes, let's say it deliberately lied to, the day soon comes that no other course seems open but complete rejection of the status quo. The chronology, seen throughout history, of deferral, disappointment and rising public frustration with glacial progress towards a state of affairs that might offer better local governance, speaks directly to Hong Kong's parlous situation.
As I wrote in this column three years ago, when Occupy gradually became inevitable, everyone in Hong Kong's political spectrum from pan-democrat ranters to United Front zombies and hopelessly out-of-their-depth bureaucrats was dangerously in the wrong. Nothing substantive has changed for the better. It remains to be seen if the incoming administration can bridge seemingly impassable chasms, or whether Hong Kong's deeply unfunny political farce will eventually dissolve into tragedy.
Category: Hong Kong


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CLL Computer Club
The Club was organized to promote computer literacy for
the CLL members and to help develop a pool of instructors and teaching
assistants for the computer classes.
As personal computers become available and affordable for most homes, they have also become more powerful. The concept of computer literacy is moving beyond computer basics to more powerful applications under the heading of multimedia literacy. Our Computer Club has expanded its scope to fill these growing requirements.
Eligibility for Membership
All CLL instructors, faculty and students who are interested in keeping abreast of the fast changes in computer technology and sharing their computer knowledge and experience are eligible to join our growing numbers of club members.
Meeting Place and Time
Place: UWF, Fort Walton
Beach Campus
Building 3, Room 368. This is a temporary location; the Club will meet in Room 357 when construction in that room is finished.
Date and Time: Second Tuesday of every month at 10:00 am. The meeting will finish no later than 12 noon.
Typical Meeting
The meeting starts with a Question and Answer/problem solving session followed by a computer related presentation by either a club member or an outside guest speaker.
We do not always solve all computer problems, but we do help in sharing your pain.
Club Officers
The Club President "Lead Digerati" Jim Cooper organizes and hosts the meeting each month. The Club Secretary, Judie Day, keeps the membership list up to date and sends out announcements of upcoming meetings and handouts provided by the presenters via e-mail.
Judie also does the publicity and promotion.
The Club now has a membership of 67 members (and growing) with an average of 30 to 35 attending each session. Our membership includes locals, transplants, and snowbirds. They are a good cross section of the United States and Canada.
Being a CLL member is the only requirement for membership. There are no dues or fees.
News: The club now has an
e-mail address; you can reach us at


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Answered By: ask crisslibrary Last Updated: May 06, 2015 Views: 26
Answered By: ask crisslibrary
Last Updated: May 06, 2015 Views: 26
If you want to set up an account, you can do so at this page: https://unomaha.illiad.oclc.org/illiad/NBU/illiad_firsttime.htm. If you already have an account, you can sign in here: https://unomaha.illiad.oclc.org/illiad/NBU/. That last page also has a link you can click if you forgot your password. If you still have problems, you can call the interlibrary loan office at 554-3209.
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|1st United States Flag
|Rhode Island Flag
A special thanks also to all musicians for their wonderful music helping define the character of the American People and historical sensitivity of the history of Rhode Island Revolutionary War Major General Nathanael Greene, who author David McCullough agrees is the Greatest Forgotten Hero in American History. Viewers are not authorized by law to copy the sound or imagry contained on this Web Page. FBI Warning: Unauthorized duplication or recording of this material is prohibited by U.S. Federal Law and is protected by copyrights including all sound and imagery, which are ©2006 Nathanael Greene Homestead Museum, Spell Hall or by other contributing artists, designers and authors.
This site is managed by: Gregg A. Mierka, Webmaster, C/O Gen. Nathanael Greene Homestead Museum, at Spell Hall, Coventry, R.I.
A special thanks also to Pulitzter Prize Author-Historian David McCullough, who agreed General Nathanael Greene is the Greatest Forgotten Hero in American History, and something must be done about that.
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In this section
Below are the summary notes from the fifth meeting of the SLG for season 2017/18
Below are the summary notes from the fourth meeting of the SLG for season 2017/18
Below are the summary notes from the third meeting of the SLG for season 2017/18
SLG Notes 19.11.pdf
Also, please see the questions and response to specific questions tabled by DUSF ahead of the SLG.
DUSF response.pdf
Below are the summary notes from the second meeting of the SLG for season 2017/18.
Below are the summary notes from the first meeting of the SLG for 2017/18 season.
If you want to play your part in shaping the future of Dundee United Football Club, its relationship with its fans and how the match day experience develops, you can apply now to be part of the newly expanded Dundee United Football Club Supporters' Liaison Group (SLG).
The SLG was created last summer to encourage greater supporter interaction and after a successful trial season, the opportunity is now there for more fans to become a SLG committee member and have their voices heard.
The new format will see each of the established supporters' groups receive one position on the SLG and we invite United fans to get in touch if they wish to play a part in shaping the future alongside these supporters' groups as a collective SLG.
Up to six independent supporters will be chosen to join the SLG and all positions will be reviewed and selected on an annual basis.
To express an interest in becoming involved in the SLG for this coming season, please email firstname.lastname@example.com with a short bio of yourself and tell us why you wish to be involved in the SLG for season 2017/18. Deadline for applications is 13 September 2017.
The ideal candidates will have a passion for United as well as knowledge and experience of the issues under discussion and it would be advantageous if the applicants help the SLG reflect a cross-section of the Dundee United support regarding gender, age, location and background.
The SLG will meet regularly during the season and focus specifically on the critical issues that fans have raised. Directors and key members of staff at the Club will attend meetings to discuss operational rationale.
The SLG will provide a platform for discussion and resolution. Key issues such as ticket availability and pricing, stadium matters, relationships and communication between different supporters' groups, equality and diversity, Club communications, commercial and Club shop products will all be open to discussion.
Summary notes from each the meetings along with other SLG information will be displayed on the new Club website.
Alongside the regular meetings throughout the season, Club Chairman Stephen Thompson, directors and senior officials will meet the SLG twice per season at Tannadice to ensure the board are connected to and communicating with our support base.
Dundee United are determined to make sure that all supporters are treated equally; this is the ethos of the improved fans' engagement process. All United fans are invited to apply for a place on the SLG and supporters will be able to keep track of SLG activity by visiting the new Club website where minutes will be uploaded within seven days of meetings.


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Visit Edmunds.com for a complete listing of local car dealerships in Sheffield Lake, Ohio. Find the best deal on your next vehicle with online discount price quotes on car, truck, SUV, and minivan models. With the ability to compare prices on new and used vehicles in Sheffield Lake, Edmunds.com makes the car buying process convenient and cost-effective. Search for car dealerships in Sheffield Lake, Ohio with our comprehensive dealership network and avoid the common hassles associated with car shopping.
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Tier pricing is a promotional tool that lets you price items differently in correspondence to their quantity.
Tier prices used for those customers who are willing to order multiple products, and you want to reward them by giving a discount.
You can create tier prices in Store Manager to manage them or import them from a .csv file during products import.
To import tier prices you need to have correct .csv file with tier prices added. The .csv file should also contain product identifier, so you could assign the corresponding tier prices to correct products.
Run the process of products import and it will import your tier prices very quickly.
You need to assign the column "Tier Price" of .csv to the appropriate database field at the 6-th step of import process:
As soon as the import completed, you can check import results at:
Please, also check for these useful articles:
How to ...(part1) >


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We have been using Copylam's services for the duration of our two-year project and are very happy with their service. Even when we're under pressure or trying to meet a tight deadline (which is almost always), we feel confident Copylam will do an excellent job, on time and within budget. Copylam always deliver – and if they can't (we often ask for things outside their scope), they go above and beyond to find someone who can. Thanks Richard and the Copylam team for making us look good!
As a NSW agency attending an interstate event, Copylam's professional service was really invaluable... not only did they complete a large job in a short time, their communication with us really gave peace-of-mind. Thanks Copylam!Amy - Game Licensing Unit, Department of Primary Industries
One thousand thank-yous to Richard and the team at Copylam. Our eleventh hour order was completed in record time, when no one else could help us. Richard went above and beyond for us and we will be recommending him to all of our friends. Such a professional and easy- going attitude, thank you again!
Katherine - 10 feet tal
Thank you so much they are amazing, love your work mate. Appreciate the quality and workmanship. (Custom business cards)Jake Bui Photography, Brisbane, Qld
Just looking at the calendars again. I wanted to say thank you so much they look great and I'm so happy with how they have turned out.Cathy, Toowoomba, QLD
I want to express my gratitude and appreciation for all the work you did for us for our wedding. The final products were fantastic quality and all our guests loved them. We really appreciated your attention to detail and making sure we were happy with the final outcomes. Thank you for doing last minute jobs for us and having everything ready on time.
I cannot say how thankful we are - having you dealing with our invites, displays, thank you cards and everything else really made things so much easier.
Thank you, and Merry Christmas.Steph Toowoomba QLD
Thankyou to Warren and the Team at Copylam! They rescued me in my hour of need and were able to prepare some Business Cards for a friend of mine, at the 11th hour and when we thought all was lost. Prompt and efficient service, with excellent pricing – what more could you ask for? I'll be returning to Copylam for all of my printing needs in the future and will be recommending them to everyone I know. Thanks again guys. Kind Regards, LeahLeah, Toowoomba
"I just wanted to send a quick email to say thank you for all your help and patience regarding the business cards. Your replies were quick and professional. You went above and beyond in relation to my expectations as a customer."
"Looking forward to doing business with you again soon."CHS Bricklaying, Canberra, ACT
"Copylam went out of their way to create a Presentation Folder to our specifications. We were very impressed with their level of customer service and communication. Thank you Copylam, we will definitely be using you again in the future"Smile IT, Brisbane


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Here is a short list of some of TSP's favorite flicks. Stay cool on this hot summer day. I am thinking perhaps a movie viewing in sub zero temps is just what the doctor ordered. Enjoy!
The Gladiator – Favorite Epic
I love me a good epic and this one continues to reign supreme on my list of top flicks. Russell Crowe plays a war hero turned gladiator who goes to Rome to seek revenge on the corrupt son who murdered his family. Ancient Rome and the Colosseum are brought back to life on screen and this incredibly gut wrenching tale unfolds within one of the most incredible ancient cities of all times. This is a must see.
The Sound of Music – Favorite Movie Musical
Julie Andrews plays a nun turned governess aka au pier for a a widowed naval officer. Maria shares her gift of song and music with the seven children she is caring for and the children's father and she accidentally fall in love. Likely story, I know, but it is one of my favorites and if you haven't had a chance to sit down and enjoy it, now is the time.
Harold and Kumar Go To White Castle – Favorite Stoner Flick
The title pretty much sums it up. Harold and Kumar are pals/stoners and they get the munchies and go on a trippy adventure for White Castle. This is the exact opposite of a cerebral movie, thus the stoner flick genre, but if you like to laugh and have the slightest sense of humor, then I promise you will giggle. Ya might consider getting blazed yourself.
The Family Stone – Favorite Holiday Flick
Sarah Jessica Parker plays the worst human possible as a wound up too tight, successful business woman who goes home for the holidays with her boyfriend, played by Durmot Mulroney (yes please) and finds herself pretty lost within this super liberal, very dynamic, fun loving family. It is nostalgic and heart warming and will tug at you heartstrings.
Amelie-Favorite Foreign Film
French film alert! I love, well, I am more like obsessed with Parisian life. Here you have a beautiful, whimsical, romantic comedy depicting Parisian life exquisitely. Meet Amelie, a young beautiful girl raised by a couple of pretty eccentric parents convinced she was ill, keeping her from experiencing a normal child's life. One thing leads to another and Amelie becomes inspired and devoted to bringing random happiness to people by doing the most creative and beautiful things. The love in this story is lovely and sweet. The soundtrack has been making love to my ears since 2001 and the storyline and cinematography is unparalleled. Pop open a bottle of Rosè and get ready to fall in love with Amelie and her quirky, beautiful self.
Drop Dead Gorgeous-Favorite Comedy
This right here is a classic. Right up there with Gone with the Wind. First off, Brittany Murphy is in it. Love(d) her. It is a fictional document style comedy where contestants of a beauty pageant from Mount Rose, Minnesota, are followed and interviewed. The young and talented (you're going to laugh your ass off) pageant girls begin dying off in very mysterious ways. Oh, and one of the moms is in an explosion and her beer can melts to her hand and she continues to use it as an ashtray. Brilliance at its best! You're welcome.
American Beauty-Favorite Drama
Go ahead and grab the popcorn. This film is about a middle-class, middle aged man who basically hates his life. He becomes obsessed and completely infatuated with… wait for it…. his teenage daughter's best friend. Yep. And that's not all. We got a pot dealing neighbor with a homophobic dickhead dad, a slutty and seductive cheerleader, an insecure teenage girl, and a materialistic and ambitious wife. We also got cheating, we got lying, we got rose petals falling all over the place. Pop this in and probably pop a boner but be ready for that thing to go down quick because the twists are unreal.
Love Actually-Favorite Romantic Comedy/Holiday Movie
I am a real sucker for the holidays and an even bigger sucker for a killer romantic comedy. Make it a British film and you bet your ass it's a favorite of mine. Ten peoples hearts are followed during the hectic and exciting weeks before Christmas. There are so many different and at times intertwined love stories here. There is love between friends, children, parents, dudes who want to bang American chicks, famous musicians, politicians, work affairs, sibling love, unexpected love…you name it. It is beautiful, funny, sweet, and uplifting. Oh, and there are christmas songs to boot!
Be sure to check out the Mid Sis's review of the documentary, Amy. She was lucky enough to get a sneak peak before it was released and it has definitely been added to my list of "must sees." Still not satisfied? Here are The Mr. Project's list of must see movies for the rest of 2015.
Love it. Live it. Share it.


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We are very keen to keep in touch throughout the season, so if your contact details change we encourage you to update
these online through your MyBulldogsAccount. Simply log in using your member number and password.
- You can log in to MyBulldogsAccount to renew your membership
- You can reset your member account password
- You can view your order history - check on previous memberships and orders
- You can update your credit card details - to apply a new credit card to an existing Committed Bulldog payment plan a payment must be made.


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Individual • Business • Club/Team • Event
Bike education materials for your classroom, youth organization, and more.
Bike Lights, Jerseys, License Plates, T-Shirts, and more
Share your love for bikes while driving your car
Support Bike Advocacy & Education
Premiere Business Members & Sponsors
Get certified to teach the SafeCyclist Curriculum
Resources for teachers and community members
On February 3rd, 2005, Bahram Daneshvar and Charles Thiele, both visiting Fredericksburg from Minnesota, set out on their bicycles to experience the fabled Texas Hill Country.
The two cyclists were touring with a group of about 50 cyclists from Minnesota that had traveled to Fredericksburg specifically to ride the roads which have made the Hill Country a national destination for bicyclists.
As Published - TBC Listserve - 5-21-2005
by Guy Taylor
One thing that really ticks me off is a cyclist that makes no effort to assist the passing of a motor vehicle but "hogs" the road. The car v. cyclist attitude that many riders have created from years of fighting traffic hinder our efforts for equal access. What ever happened to the "Drive Texas Friendly" attitude we used to have in this state.
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Day 1. Arusha - Kuro Tarangire
From the bustling north Tanzanian town of Arusha to the little gem of Tarangire National Park. The mountain landscapes give way to the arid Acacia and baobab of the Maasai steppe: this is rich big game country and ripe for exploring. Overnight at our beautiful bushcamp, Kuro Tarangire.
Accommodation: Kuro Tarangire
Day 2. Tarangire
From our stylish tented camp, we can walk straight into the bush in search of giraffe or zebra, game drive over to the Silale swamp where the eles hang out or look for big cats under cover of a night drive. We love that our little patch of Tarangire is remote yet in the middle of the action. Overnight Kuro Tarangire.
Accommodation: Kuro Tarangire
Day 3. Tarangire - Ngorongoro Crater
From Tarangire, drive up to the lush Ngorongoro Highlands where forests, monkeys, coffee farms and lush gardens are the norm. You might stop off for a picnic and game drive in Manyara National Park en route. Arrive at our newest camp, Entamanu Ngorongoro and sit back to enjoy the spectacular views over the Crater and surrounding Highlands. Overnight Entamanu Ngorongoro
Accommodation: Entamanu Ngorongoro
Day 4. Ngorongoro Crater & Highlands
An early departure to make the best of the day in the Ngorongoro Crater. One of Tanzania's most famous landmarks, the crater is known for both it's wonderful scenery and also the varied wildlife that thrives inside. Spend the morning game driving with your guide, and enjoy a picnic lunch on the crater floor. Return for a relaxed afternoon or perhaps a walk into the Highlands, with sundowners watching the sun dip below the horizon over the Southern Serengeti plains. Overnight Entamanu Ngorongoro.
Accommodation: Entamanu Ngorongoro
Day 5. Ngorongoro Highlands - Northern Serengeti
Fly from Manyara to the central/northern Serengeti. Meet your Nomad car and guide and head on a game drive towards camp. Settle into camp for a siesta after lunch and venture out for a game drive in the late afternoon returning to camp for drinks around the fire and dinner. Overnight Serengeti Safari Camp
Accommodation: Serengeti Safari Camp
Day 6. Serengeti - Mara River/Bologonja Area
Discuss the day's activities with your guide over a camp breakfast; he'll know the whereabouts of the migration and all the other creatures of interest. Sometimes the herds are spread throughout the Nyamalumbwa and Bologonja plains and sometimes they are frantically crossing the Mara River. Wherever they are, our camp will be well located for the action. Overnight Serengeti Safari Camp
Accommodation: Serengeti Safari Camp
Day 7. Serengeti - Mara River / Bologonja area
An early start today, perhaps with a picnic breakfast or lunch in search of the great herds. Of course it's not all about the wildebeest and you'll be on the look out for elephant, buffalo, big cats and even rhino. Linger when you find something of interest as so much of the pleasure of this place is the freedom you feel being in the middle of nowhere. Return to camp for a hot shower and delicious meal. Overnight Serengeti Safari Camp
Accommodation: Serengeti Safari Camp


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Celebrating 50 Years as Carnegie Mellon UniversityWe pay tribute to the innovations and innovators who have transformed education, our society and our world over the last 50 years. Learn more
Andrew Carnegie famously said, "My heart is in the work." At CMU, we think about work a little differently...
- Aug 27 Fall semester begins
- Sep 3 Labor Day; No classes


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GVP Proofreading Workshop 2014
Respected Devotees, Please accept our humble pranama. From March 31 through April 12, some of the GVP proofreaders living in Vrndavana participated in a five day workshop totaling six hours. The workshop is now in pdf format. It is easy to read and is organized according to topic, with a complete contents page. The workshop contains numerous examples […]Read more


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After data entry, the system indexes the elevator, positions the first tray and moves the tray to the X/Y loading station.
A "pick and place" arm removes the part from the tray and loads it into the spindle nose.
The loading arm has dual or quad end effecters for insertion and removal of either blocked parts or blanks from the spindle nose and the loading trays.
During the roughing cycle, the arm returns the cut part to the holder, picks up the next part and waits for the finish cut to be completed. This keeps load/unload time to a minimum.
All loader movement is completed prior to the start of a finish cut to minimize vibration.
DAC International offers the industry's most comprehensive lens manufacturing software — easy to use and easy to customize. Full maintenance and calibration capability is built into our software, as well as on-line editing
Full details on DAC International Software


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Join Terri Wagner for an in-depth discussion in this video Using status meetings to check in, part of Project Management: Preventing Scope Creep.
…Project status meetings allow project team members and customers…to stay informed of project performance, problems, issues, and expectations.…As project manager, you're able to gather the information during the…status meeting and communicate the information…to project stakeholders in status reports.…A mature organization will support and encourage full…disclosure of what is occurring on your project.…Less mature organizations may often play that game called shoot the messenger.…
When there is open, honest communication, full…disclosure, during the status meetings, we can see…when the projects are tracking to the…constraints, and see when we are experiencing slips.…One dangerous form of scope creep is that which is unreported.…When the added scope goes undocumented and unevaluated, we will not…know the cost and schedule impacts, until we…start seeing schedules slip and budgets being over run.…Then, not until a deeper dive is done, do we uncover the…truth behind the extra money and time being spent on the project.…
Lynda.com is a PMI Registered Education Provider. This course qualifies for professional development units (PDUs). To view the activity and PDU details for this course, click here.
The PMI Registered Education Provider logo is a registered mark of the Project Management Institute, Inc.
- What is scope creep?
- Why does scope change?
- Factoring in organizational maturity
- Setting scope and requirements
- Building a budget
- Resetting unrealistic expectations
- Resolving communication issues with stakeholders

- The PMI Registered Education Provider logo is a registered mark of the Project Management Institute, Inc.


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Carbone, Marrone, Ruby Reflections, Quartz Reflections, Smoky Ash and Chocolate Truffle.
As stated in the Caesarstone Press Release:
Ruby and Quartz Reflections have been two of CaesarStone's colors for the past several years. The colors contain post-consumer recycled glass.
Carbone and Marrone colors both contain recycled CaesarStone material. These wondrous colors are created by taking remnants from fabricators after production and mixing in new CaesarStone material. These two shades are only available in New York, the Northwest or by special order.
The two new additions in 2009 to the Recycled Collection are Chocolate Truffle and Smoky Ash. They are both comprised of post-consumer recycled glass.
We will look forward to further details from Caesarstone regarding the quantities of recycled content and how the material will help organizations meet their LEED objectives.


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Department of Economic Security
Providing Opportunity, Assistance and Care for Arizonans in need!
Direct Support Professional (Direct Care)
Division of Developmental Disabilities
6740 S. Tucson Boulevard
Tucson, AZ 85756
The Division of Developmental Disabilities (DDD) is seeking an experience and highly motivated individual to join our team as a Direct Support Professional (Direct Care). This position requires a caring individual to assist members who have Developmental Disabilities (i.e., autism, cerebral palsy, intellectual disability or epilepsy) ranging from moderate to severe.
- Encourages and involves members with developmental disabilities in recreational activities available at home or in the community during leisure time
- Communicate (verbal and/or written), reads, writes and follows directions; implements Individual Service Plans (ISP) programs and strategies, collects and records data
- Administers, orders and stores medications of members according to doctor's orders
- Prepares, cooks, sets up, serves and assists members with developmental disabilities in eating meals; encourages member participation in meal-time process and ensures nutritional requirements are met
- Completes general housekeeping duties as assigned
KNOWLEDGE, SKILLS AND ABILITIES (KSAs):
Knowledge of:
- Planning processes
- Providing personal care
- Human rights
- Cleaning and basic housekeeping
Skill in:
- Planning activities designed to meet specific needs of individual members
- reference.
- Time and work management
- Participating in and implementing Individual Support Plans
- Using a computer, including email
Ability to:
- Display compassion with respect to others
- Attend staff training
- Apply the basic principles of program training and data collection designed to meet the specific needs of members including medication administration
- Learn and use nutritional principles and special mealtime techniques
- Learn and apply behavior support techniques
- Must be 18 years of age to apply
- Willing to work weekends, holidays, overtime, and change work locations, when necessary
- Read and write English
- Have a current, valid state issued driver's license appropriate to the assignment. Employee is subject to driver's license record checks and must maintain an acceptable driving record, valid motor vehicle insurance and registration, and must complete any required training (see Arizona Administrative Code R2-10-207.12)
- Employee shall have a valid level one fingerprint clearance card issued pursuant to Arizona Revised Statute 41-2758.07 to be able to work with children and vulnerable adults
- Candidates for this position shall be subject to a search of both the Child Protective Services Central Registry pursuant to A.R.S. 8-804 and the Adult Protective Services Registry pursuant to A.R.S. 46-459
- Successfully pass background and reference checks. Employment is contingent upon completion of a post-offer medical/physical examination and the agency's ability to reasonably accommodate any restrictions.
The Department of Economic Security offers a comprehensive benefits package to include:
- Sick leave
- Vacation with 10 paid holidays per year
- Health and dental insurance
- Retirement plan
- Life insurance and long-term disability insurance
- Optional employee benefits include short-term disability insurance, deferred compensation plans, and supplemental life insurance
Positions in this classification participate in the Arizona State Retirement System (ASRS).
Please note, enrollment eligibility will become effective after 27 weeks of employment.
If you have any questions please feel free to contact 520-638-2684 for assistance.
Persons with a disability may request a reasonable accommodation such as a sign language interpreter or an alternative format by contacting 602-364-3981. Requests should be made as early as possible to allow time to arrange the accommodation. Arizona State Government is an AA/EOE/ADA Reasonable Accommodation Employer.
There are no jobs currently listed.


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The tatami feels good, and it smells good.
We have 10 Japanese style rooms at Hiroshima Hana Hostel.
6 of them are standard 6-jo(jo: num. of tatami mats, 6畳) room with private shower that we call unit bath in Japanese(prefabricated bath). The rest of them are a little differ in width.
We refaced all the tatami mats of Japanese rooms at Hiroshima Hana since we opened in 2008.!(some have not refaced yet!).
Refacing tatami mats are suggested regularly to maintain the condition properly.
Since my explanation for tatami is not enough, so I would like to introduce one website writes about tatami:
If you would like to try fresh tatami mat equipped room, stay Hiroshima Hana!!
Book now!!
Hostelworld: Hirosihma Hana Hostel
Fresh Tatami rooms are waiting for your stay
Sunday, June 08, 2014 haya No comments
The tatami feels good, and it smells good.


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How to Store Pool and Spa Accessories in a Creative Way
05/19/2017 | Categories: Outdoor Living
Storing Pool & Spa Accessories in College Station, Brazos Valley & Bryan
Does your pool look like a disaster area every time it gets used? Are there pool chemical bottles, towels, pool toys, and more all over your backyard? A pool and outdoor features can really bring your backyard to life, but all of the stuff that comes along with it can really make it look kind of cluttered. Here are some great ways to store pool and spa accessories in a chic, fun, and stylish way.
Take advantage of secret spaces
There are a lot of products out there that can serve two purposes for your pool. For example, if you have a deck around your pool, consider making some of the seating with a lid that opens up to allow for storage of pool accessories. There are many outdoor living pieces that are designed today with storage in mind – from ottomans to tables and much more, find the ones with a dual purpose…aesthetic and functionality.
Use large hooks
These can be attached to a wall or fence and offer a great way to store your items in a way that looks neat and clean. While they won't be completely out of view, you can maintain the beautiful look of your pool by putting these hooks in more hidden areas. If you don't want to hide your items or don't have the space, install the hooks along with decorations around them. For example, you can find some large letters to spell out your family's names.
Buy specialized containers to store pool and spa accessories
These come in a range of sizes and colors to match with the design of your backyard. Remember to pick storage bins that will go along with the current aesthetic of your pool. Some storage bins for pools are not enclosed – which means that you can still see all of the items being stored. Depending on the feel of your backyard, you may decide to buy a storage bin that completely covers what is being stored.
No matter how you store pool and spa accessories, make sure that you're doing so in a safe way. Keep chemicals and pool equipment out of reach of the little ones and instruct them to steer clear from it. Decide what kind of storage will allow you to keep a beautiful and stylish backyard while still being functional.
Founded in 2005, Sunshine Fun Pools is the leading pool builder in Brazos Valley; building more than one-hundred pools each year while maintaining 98% customer satisfaction rating. Sunshine Fun Pools specializes in custom pool design, quality pool construction, pool remodeling and pool maintenance services.
Call Sunshine Fun Pools today if you are looking for a professional, qualified customer pool builder in the College Station Bryan area. For more College Station & Bryan Pools pool design tips, subscribe to their blog and YouTube Channel or 'Like' them on Facebook. You can also read their customer reviews to learn more about the exceptional services they provide.
Ready to get started on your own backyard oasis? Contact the College Station, Bryan pool experts at Sunshine Fun Pools today!


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absOrb is a colorful anti-shooter. It's about collection, not destruction.
The basic point of absOrb is to collect as many orbs as possible. You control a ring of color to collect the orbs. Simply move your mouse to where you want the ring to go. As the game progresses, different colored orbs will be released (you'll know because the screen will flash). To toggle the ring through the colors you have available, simply press the left or right arrow keys (or the 1 - 4 keys) on your keyboard.
The special "Chrome" orb allows you to collect orbs of any color for a limited time. Clock orbs may slow down or speed up time, white orbs give you an extra life, but stay away from the dark orbs!
Developed by GoldCartridge.com using the EffectGames.com engine.