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Associate Professor of History
On leave for fall 2018 semester
Hubbard Hall - 23
18th-20th Century Russia and the Soviet Union; socialist culture; 19-20th Century Germany; First World War; Second World War; women in modern Europe; visual culture
18th-20th Century Russia and the Soviet Union; socialist culture; 19-20th Century Germany; First World War; Second World War; women in modern Europe; visual culture
My research focuses on the intersection between religious belief and everyday life in the experience of ordinary Russian people during 19th and 20th centuries, including the so-called "godless" Soviet period. I am interested in the diverse and evolving ways that individuals understood the role of God and faith in their lives, selves and communities – both what they valued as sacred, and how their beliefs gave them a framework for acting, understanding change, and structuring society. These questions are relevant to Russia's past as well as its present, as Russians today debate the role that the Orthodox Church should play in modern society and politics, and the relationship between Orthodoxy and "Russianness."
At the center of my current book project, "Defying Orthodoxy," is the collective experience of the tens of thousands of devout Russian Orthodox believers who, over the course of the last century, have challenged dominant norms of faith, authority and identity in order to proclaim their personal salvation through the teachings and prayers of a charismatic lay preacher known as "Brother Ioann" Churikov (1861-1933).
My first book, Working Souls: Russian Orthodoxy and Factory Labor in St. Petersburg, 1880-1917 (Bloomington, Indiana: Slavica Publishers, 2007), addressed questions of religious (and irreligious) identity among workers in Russia's most revolutionary and modern city, St. Petersburg/Petrograd. While documenting the remarkable vitality and diversity of urban religious life at the end of the Imperial era, it explores the various ways in which the components of workers' religious identity – their practices, sensibilities, and beliefs about God, self and society – were transformed by the experience of modern factory life. It also considers the extent to which the evolving spiritual needs and demands of the working class laity precipitated changes in Russian Orthodoxy and the role of the Church in modern society.
"Zhizn' v Kommune BICh v 20 godakh" ("Life on the Churikov Commune in the 1920s"), forthcoming in Russian in a conference volume, "Dvizhenie 'narodnykh trezvennikov'" (St. Petersburg).
"The Pious Women of an 'Unsimple Folk': Female Perspectives on Faith and Authority Among the Orthodox Laity of St. Petersburg, 1895-1917," Church and Society in Modern Russia: Essays in Honor of Gregory L. Freeze eds. Manfred Hildemeier and Elise Kimerling Wirtschafter (Wiesbaden: Harrassowitz Verlag, 2015), 113-132.
"Orthodoxy and the Politics of Emotion in the Case of 'Brother Ioann' Churikov and His Followers, 1910-1914," in Orthodox Parodoxes: Heterogeneities and Complexities in Contemporary Russian Orthodoxy (Brill, 2015).
"Worker Cultures in Revolutionary Russia, 1914-1922," in Russia's Great War and Revolution, 1914-1922. The Century Reappraisal (Slavica, 2014).
"Petitions to Brother Ioann Churikov," in Orthodox Christianity in Imperial Russia: A Sourcebook on Lived Religion, ed. Heather Coleman (Indiana University Press, 2015).
"Villain or Victim? The Faith-Based Sobriety of the Factory Worker Peter Terekhovich in Soviet Russia, 1925-29." Europe-Asia Studies, Vol. 65, no. 9 (November 2013): 1737-54
"Trials of the Unorthodox Orthodox: The Followers of Brother Ioann Churikov and Their Critics in Modern Russia, 1894-1914," Russian History 40 (2013): 244-63.
"The Religious Landscape in Revolutionary St. Petersburg, 1900-1917." Journal of Urban History 37:6 (November 2011): 842-857.
«Из истории неортодоксального православия: «преступления» братца Иоанна Чурикова и его последователей в России в 1905-1914 гг.» ["A Case of Unorthodox Orthodoxy: The 'Religious Crimes" of Brother Ioann Churikov and his Followers in Modern Russia, 1905-1914."] in "Vina i Pozor v kontekse traditsionnoi kul'tury," eds. Marianna Muraveyva and Natalia Pushkareva (St. Petersburg: European University Press, 2011).
"Raising Lazarus: Orthodoxy and the Factory Narod in St. Petersburg, 1905-1914," Jahrbucher fur Geschichte Osteuropas, vol. 52, no. 3 (2004).
"Orthodoxy and the Experience of Factory Life in St. Petersburg, 1881-1905," in New Labor History: Worker Identity and Experience in Russia, 1840-1918, ed. by Michael Melancon and Alice Pate (Slavica, 2002).


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Restoration Hardware Unveils New Store in Houston
Restoration Hardware knows how to throw a party. For a while I've been keeping tabs on the progress of their new location in Houston's Highland Village, and this Thursday night patience was finally rewarded when the store was opened to (select members of) the general public. On behalf of Apartment Therapy, I was there to scope it out.
My friends were confused when I told them I was going to a party at a furniture store. But this is no ordinary furniture store. It is 25,000 square feet of vignettes designed to wow you at every turn. Imagine a giant manor house plunked down in the middle of metro Houston. Sort of like a zoo for furniture, where you can see all the pieces in their natural setting.
Also visible in their natural setting, on this particular evening, were the cream of Houston society, bedecked in furs and sipping bellinis by Cipriani while listening to music by Swedish band Lykke Li. I wandered about, taking in the roof deck, the caged chandeliers, and the overwhelmingly comprehensive selection of teas. I had a lovely evening, and also came to an important realization: I would buy a lot more furniture if every store I went to served free drinks.

subset: commoncrawl


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Lagothrix lugens
|Scope: Global
Language: English
|Scientific Name:
|Lagothrix lugens Elliot, 1907
Common Name(s):
Lagothrix lagotricha ssp. lugens Elliot, 1907
Lagothrix lugens
|Taxonomic Notes:
|The taxonomy of Lagothrix is based on Fooden (1963), but follows Groves (2001, 2005) in recognizing cana (E. Geoffroy, 1812), lugens Elliot, 1907, and poeppigii Schinz, 1844 as full species rather than subspecies of lagotricha (Humboldt, 1812). Groves (2001, 2005) also recognized the form tschudii Pucheran, 1857, from Peru (see Cruz Lima 1945).
|Red List Category & Criteria:
|Critically Endangered A3cd ver 3.1
|Year Published:
|Date Assessed:
|Stevenson, P. & Link, A.
|Mittermeier, R.A. & Rylands, A.B. (Primate Red List Authority)
Listed as Critically Endangered as it seems reasonable to expect that the population of this species will decline in the order of 80% over the next 45 years (three generations) due primarily to the effects of habitat loss and hunting.
|Previously published Red List assessments:
|Range Description:
|The range was delimited by Defler (2003, 1004) and Hernández-Camacho and Cooper (1976). Occurs to the north of the lower Río Guayabero, where it is scarce (Klein and Klein 1976). More common through the piedmont of the Uribe region (between La Macarena and the Cordillera Oriental and in the Serrania La Macarena). It extends north to the along the eastern slopes of the Cordillera Oriental to about 3,000 m. In Central Colombia, L. lugens extends from the upper Magdalena valley to at least southern Tolima, west of the of the Río Magdalena and historically at least to the southern part of the Department of Cesar, on the west side of the Cordillera. It is almost certainly extinct there today. There is an isolated enclave in the Serrania de San Lucas in south-eastern Bolivar and northern Antioquia at the northern end of the Central Cordillera. The San Lucas population, studied briefly by Kavanagh and Dresdale, 1975), may have been connected to the populations of the upper Magdalena valley when there was forest there. L. lugens meets L. lagothricha somewhere in the Department of Caquetá, but exactly where is not known.
Bodini and Pérez-Hernández (1987) reported that no woolly monkeys have been collected in Venezuela, but that they would expect L. lugens to occur in the Selva San Camilo. State of Apure (following the distribution proposed by Fooden [1963] and Hernández-Camacho and Cooper [1976]).
|Countries occurrence:
Native:Colombia (Colombia (mainland))
|Additional data:
|Range Map:
|Click here to open the map viewer and explore range.
|Occurs at densities of up to 50 individuals/km² in protected areas (P. Stevenson pers. comm.).
|Current Population Trend:
|Additional data:
|Habitat and Ecology:
|Occurs in primary forest from lowlands up to elevations of 3,000 m. They have also been recorded in gallery and Mauritia palm forest odf the eastern plains of Colombia as well as in seasonally flooded forest (Hernández-Camacho and Cooper 1976; Klein and Klein 1976; Moynihan 1976). Studying a group of L. lugens in the Tinigua National Park, Colombia, Stevenson et al. (1994) observed a preference for mature forest (82% of the group's time spent there) over open, degraded forest (11%) and flooded forest (5%).
In 1967, Klein and Klein (1976) made some observations on the habitat and distribution of this species in La Macarena Natural National Park, Colombia, and Bernstein et al. (1976a) and Kavanagh and Dresdale (1975) made a brief study of its behaviour in a patch of cloud forest in the Serrania de San Lucas, Bolívar, Colombia. Woolly monkeys are frugivores, eating also young leaves, leaf buds, flowers, nectar and bark (Ramirez 1980). Stevenson et al. (1994) reviewed observations on group sizes in the Tinigua National Park. Seven groups observed during the late 1980s and early 1990s ranged in size from 14 to about 33. One of the groups (17 individuals: 4 adult males, 5 adult females, 1 subadult male, 1 subadult female, 2 infant males and 2 infant females) ranged over 169 ha.
Late maturation and long inter-birth intervals (typically around 3 years) makes it difficult for them to recover from hunting and other threats. Females begin mating at 5 or 6 years of age, when they leave their natal groups, but do not conceive until 1.5-3 years later (Nishimura et al. 1992).
|Major Threat(s):
|The major threats are hunting for food (mainly subsistence) and habitat loss due agricultural development/expansion. Habitat loss is also taking place due to clearance of forest for coca plantations, accompanied by fumigation of coca plantations that results in defoliation of contiguous forests. Late maturation and long inter-birth intervals (typically around 3 years) makes it difficult for them to recover from hunting and other threats.
|Conservation Actions:
This species occurs in the three contiguous protected areas of:
La Macarena National Park (630,000 ha) (see Nishimura and Izawa 1975; Nishimura 1986; 1988, 1990a,b; Stevenson 1992)
Tinigua National Natural Park (201,875 ha) (see Stevenson et al. 1994; Stevenson 2000; Stevenson and Castellanos 2000)
Cordillera de los Picachos Natural National Park (286,600 ha) (in range: Defler 2003, 2004).
Also present in Cueva de los Guacharos Natural National Park (9,000 ha) (INDERENA 1989).
This species is listed on Appendix II of CITES.
|Stevenson, P. & Link, A. 2008. Lagothrix lugens. The IUCN Red List of Threatened Species 2008: e.T39926A10289596. . Downloaded on 25 September 2018.
|To make use of this information, please check the <Terms of Use>.
|If you see any errors or have any questions or suggestions on what is shown on this page, please provide us with feedback so that we can correct or extend the information provided


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21 U.S. Code § 360g–1 - Agency documentation and review of significant decisions regarding devices
prev | next
(a) Documentation of rationale for significant decisions
(1) In general
The Secretary shall provide a substantive summary of the scientific and regulatory rationale for any significant decision of the Center for Devices and Radiological Health regarding submission or review of a report under section 360 (k) of this title, an application under section 360e of this title, or an application for an exemption under section 360j (g) of this title, including documentation of significant controversies or differences of opinion and the resolution of such controversies or differences of opinion.
(b) Review of significant decisions
(1) Request for supervisory review of significant decision
Any person may request a supervisory review of the significant decision described in subsection (a)(1). Such review may be conducted at the next supervisory level or higher above the individual who made the significant decision.
(2) Submission of request
A person requesting a supervisory review under paragraph (1) shall submit such request to the Secretary not later than 30 days after such decision and shall indicate in the request whether such person seeks an in-person meeting or a teleconference review.
(3) Timeframe
(A) In general
Except as provided in subparagraph (B), the Secretary shall schedule an in-person or teleconference review, if so requested, not later than 30 days after such request is made. The Secretary shall issue a decision to the person requesting a review under this subsection not later than 45 days after the request is made under paragraph (1), or, in the case of a person who requests an in-person meeting or teleconference, 30 days after such meeting or teleconference.
Source(June 25, 1938, ch. 675, § 517A, as added Pub. L. 112–144, title VI, § 603,July 9, 2012, 126 Stat. 1051.)
LII has no control over and does not endorse any external Internet site that contains links to or references LII.


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Practice Law. Promote Justice. Change Lives.
Dan Arshack, at right, is a 1983 graduate of the Antioch School of Law, and is now practicing in New York City with his firm, Arshack, Hajek & Lehrman, PLLC. Dan and his firm were recently in the New York Law news http://www.lawahl.com/index.php.
Dan wrote us a note on his work - and I think you'll find his range of cases to be quite fascinating!
Joe Libertelli, Director, Alumni Relations
Hi Joe,
I thought you might want to know what your alumni are up to.
We are not your run of the mill defense firm. We are problem solvers and committed litigators. While most of our work is criminal defense, we do a significant amount of commercial litigation as well. We recently successfully litigated a Lanham Act (trademark) case and won a difficult and very drawn out arbitration/mediation involving the division and re-allocation of interests of a very well known NYC construction business, a variety of family trusts and property owned by a variety of LLC's.We tend to handle "unusual" and "difficult" cases often that require very prompt attention and creative and aggressive interventions. We sometimes are asked to represent co-defendants in multi-defendant cases. Here are four examples of our "interesting" cases in the last couple of years:When a major law firm decided that they could not handle a fairly "toxic" case we were asked to represent the highest ranking former official of Libya's Kaddafi regime to defect from Libya at the inception of the Arab Spring and we said "yes." The representation required protecting the client's interests in interactions with FBI, UK Investigators, Scottish Police and SEC investigators all of whom eyed our client as potentially liable for a variety of very public and deeply troubling events with which Libya had been associated from the mid 1980's to 2010. In accepting the assignment, on very short notice, we first had to learn and absorb an enormous amount of historical and factual data concerning the client's role within the Libyan government during the years of interest. This was immediately followed by two weeks of marathon meetings and negotiations with law enforcement officials from several continents in Doha, Qatar. Thereafter, ongoing interaction with those officials resulted in no charges being filed and interest in our client, thankfully (to him) waning. We were contacted by the single largest taxpayer in the Democratic Republic of the Congo (DRC) who had been identified in a very public UN report prepared by UN area experts, as a funder and supporter of rebel groups in that country. He denied the allegations and needed us to generate the evidence that the allegations were false and then convince the UN to retract the allegations made in the report. The mere fact of the allegations had a seriously detrimental effect on our client's business interests throughout the DRC and elsewhere in Africa and Europe. The assignment was made all the more difficult given the fact that active hostilities were then occurring in the DRC and more so, because there existed no process within the UN structure to address allegations such as those made in UN reports. After meeting with our client in Europe, we put a team together and developed a plan to fix the problem. We sent our intrepid top flight investigators to the DRC to take statements and generate documentary proof of the falsity of the allegations and submitted the UN's documentary "evidence" to computer forensic analysis which conclusively proved that the documents the UN experts had relied upon were forgeries and others were wholly created to impugn our client's reputation. We then engaged in a difficult and contentious process within the UN to establish our "right" to due process within that institution. After providing briefing papers to the UN and two sets of hearings during which we demonstrated the lack of integrity of the evidence relied upon by the UN experts and had our witnesses testify and provide evidence, the UN took the completely unprecedented step of agreeing to retract all of the damaging statements made against our client. Last year, we were retained to represent the owner of a New York based hedge fund, a non- U.S. citizen, who had been the subject of a prolonged SEC investigation and the defendant in a variety of civil law suits filed by unhappy investors. We became involved after he was arrested on his way out of the country after judgments totaling in the mid-eight figures had been entered against him in the SEC and civil actions. After a year of parsing the evidence and countless meetings and negotiations with the Federal prosecutors during which we developed a close collegial working relationship, we are currently preparing that case for trial this summer. Stay tuned.We were contacted by the Colorado Office of the Public Defender in the case of James Holmes the defendant in the Aurora, Colorado theatre shooting. We were asked to make an effort to subpoena and attempt to compel a Fox News reporter based in NYC to appear and to give testimony in the Colorado case. The situation arose after law enforcement officials in Colorado, in an effort to illegally influence the outcome of a death penalty case, violated a court imposed gag order by leaking confidential communications between the defendant and his psychiatrist to the Fox News reporter in NYC. The reporter is attempting to rely on her statutory journalist shield to fight the subpoena and refuse to disclose the identity of her confidential sources. She is represented by mega-firm Hogan Lovels who has been resisting our efforts and whom we beat at the trial level. Then they tried to have the subpoena stayed, twice, at the Appeals Court and we beat them both times, so they appealed. Last week we argued the case in the Appellate Division First Department (attached, find the New York Law Journal's description of that event). Stay tuned on this one as well. (But I think the Fox News reporter should plan on a visit to the Rockies.) As you can see, we don't back away from difficult cases. We revel in them. That's what UDC alumni do - and that's what we do. Please do stay in touch.Best Regards, DanDaniel N. ArshackArshack, Hajek & Lehrman, PLLC1790 Broadway Suite 710New York, New York 10019ph- 212-582-6500fax- 212-459-0568www.lawAHL.com
7 hours agoUDC Law Alumna, Student sworn in as DC Commissioners
9/17/2018"Lawyers for the People:" Alum Coury Mascagni, '12, forms New Non-Profit Law Firm
9/14/2018D.C. Vital Records Reform Bill Authored by Rudi Schreiber, '95, Signed by Mayor Bowser
9/19/2018Writing Wednesdays: Sound Sentences & Perfect Paragraphs
9/20/2018University Opening Convocation (No Morning Classes)
9/23/2018Anita: the Film, the History, and the Kavanaugh Nomination: Film and Panel Discussion
9/24/2018Law School Town Hall Meeting
UDC David A. Clarke School of Law
4340 Connecticut Ave NW
Washington, DC 20008
Phone: 202-274-7400
Admission Inquiries: firstname.lastname@example.com
General Inquiries: email@example.com


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March 18. 2013 6:06PM
UNH historian wins Bancroft Prize
Joseph W. McQuaid: Prizes & playoffs: Well done, UNH
DURHAM - A University of New Hampshire professor has been named a recipient of the 2013 Bancroft Prize.
Columbia University announce that W. Jeffrey Bolster, associate professor of history, is one of two recipients of the prize for what UNH Media Relations said in a release was Bolster's "gripping and eloquent history of the human impact on the ocean. ''
Bolster , a former seafarer himself, wrote "The Mortal Sea: Fishing the Atlantic in the Age of Sail" (Belknap Press of Harvard University Press, 2012). The other winner is John Fabian Witt of Yale University for "Lincoln's Code: The Laws of War in American History" (Free Press, 2012).
Bolster's theme is that overfishing is more than a contemporary problem.
He writes that, "Beginning the story well before industrialization emphasizes the longevity of people's short-sighted impact on the ocean, and emphasizes, as well, how modern technology was not necessary to affect the balance of nature. "
"With its deep roots, this tale is probably the longest history possible of Euro-Americans' interaction with any aspect of their natural environment, a story of unrealistic hopes, frequent articulated concerns, destruction, and denial," he said.
The Bancroft Prize is awarded annually by the trustees of Columbia University. There were 223 books nominated and considered for the 2013 prize.


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Sanford police chief job offered to Illinois deputy chief
Sanford police chief job offered to Illinois deputy chief
SANFORD, Fla. —
Sanford's city manager has offered the police chief's job to the deputy chief from Elgin, Ill.
After paring down the list of the candidates to replace chief Bill Lee, they've offered the job to Cecil E. Smith. If he accepts the job he'll be paid just over $110,000 a year.
Leaders had been considering candidates since an October forum that was held for residents to talk about what they want in a new chief.
The interim chief, Richard Meyers, has said he did not want to remain in the position.
Meyers stepped in as chief when Lee was let go in the wake of the Trayvon Martin shooting controversy.
Related: George Zimmerman At Sanford Police Dept.


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"Off the Hook" 3
Giclèe Reproduction $ 49.00
Original Drawing $ 135.00
This original production drawing by animator Jim Dewicky is from the Spaceman Jax episode "Off the Hook" in season two.
This rare piece of production artwork is stamped with the PUD Film company logo and an archival number from the Archival Department of PUD Film. The drawing comes with a certificate of authenticity.
General Details
Artist: Jim Dewicky
Year: 1962
Material: Red pencil and graphite
Paper: Animation paper
Size: 26.7 x 33.0 cm (10.5 x 13 in) - 12FLD
Spaceman Jax and the Galactic Adventures was first broadcast in 1961, sponsored by Sunnington Morn Breakfast Cereals. It was created by Bill Pendergast and Leo Ulrich, and designed by Philip La Carta (who also designed Brigadier Buffalo and Manfred J. Platypus, P.I.). The show was the first big success for P.U.D. Film, and though it originally ran for just three seasons, it has continued to enjoy success in syndication.
Sign up
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|October 3, 2012, 10:33 AM
Senior Member
Join Date: November 12, 2005
Posts: 2,536
Pull Down Powder
I'm working on this 8mm Mauser project. I'm pulling down 1955 Yugo ammo that hang fires a great deal. The primers are too hard, which is typical of that ammo. This ammo I am reloading is from a case I unsealed myself.
I used H414 in the last loads, worked ok actually. But I burned off that original powder. On this set I am going to reuse the powder and just change the case and primer.
The powder is a course flake and loads to the bottom of the neck. The Yugo ammo actually is pretty accurate when it fires. I compared the case capacities of the Yugo case and the Winchester case I am using. The Yugo case has slightly less capacity. I pulled ammo in 3/10 round sets and averaged the powder charge. I came up with a high of 40.8 grains and a low of 40.5 grains. then I pulled rounds signally and came to the same results. I'm using 40.5 grains in this load. It meters well in my Hornady lock and load auto powder measure. I will be using standard CCI primers.
I don't want to toss 900 rounds worth of powder that looks perfect and comes from ammo that is basically very accurate in my Mausers, when it fires.
I'll post how it goes
|October 4, 2012, 09:41 AM
Senior Member
Join Date: May 27, 2007
Posts: 5,261
If your mainspring is not producing enough energy for reliable ignition, put in a new one. I install new Wolff mainsprings.
For a M48 I would use the 22 pound spring, the lightest one they have, the heavier springs make bolt lift hard.
Basically I install new mainsprings on virtually all of my old bolt rifles, it really makes a difference in lock time, on military two stage triggers, it often reduces creep on the final stage.
In so far as 1955 powder, it close to the end of its shelf life, if not beyond, I would not load up hundreds of cases and have the stuff sitting around. I did that with surplus IMR 4895, before I found gunpowder has a shelf life, and within a year, I lost 700 LC Match cases due to cracked case necks. As gunpowder deteriorates it outgasses NOx, one byproduct is nitric acid gas. Gunpowder has stabilizers that consume this NOx, but given enough time, the stabilizers are gone. That nitric acid gas will ruin brass. You will see pin hole though corrosion on old ammunition, that is the nitric acid gas eating up the brass.
Also, if you get sticky extraction or "funny" retorts, stop using it . Old powder will blew up actions.
If I'm not shooting, I'm reloading.
Last edited by Slamfire; October 4, 2012 at 09:47 AM.
|October 8, 2012, 08:04 AM
Senior Member
Join Date: November 12, 2005
Posts: 2,536
I shot this load yesterday. 40.5 grains of the pull down powder. Accuracy was excellent. while the group was 4 inches it was a straight line string vertically. You could have put a straight edge along the holes. 10 shots in that group. The string is my fault. I can see well enough to keep the windage on but elevation I have trouble with. Old eyes I guess.
I think the big difference in the load was that the military load ran in a .3 grain variation and the old hard primer was inconsistent. I tossed exactly 40.5 grains and used a new primer.
I also shot a varget load with that bullet. Not good at all. Now I'm sorry I burned off that powder from the first batch.
|October 8, 2012, 01:16 PM
Senior Member
Join Date: September 15, 2007
Location: NC
Posts: 707
Year ago I pulled down a couple hundred rds. of 53 & 55 surplus berdan ammo because of primer issues,split necks and poor accuracy.
Needless to say the powder and bullets worked fine in new boxer primer cases and accuracy improved dramatically when I reduced the charge down by about 1.5 grs. from the original factory load average.
|October 8, 2012, 03:18 PM
Senior Member
Join Date: September 8, 2010
Posts: 495
I'm in the same situation, the Yugo ammo I have has a lot of duds and needs a lot of second strikes. I pulled the projectiles, but tossed the powder.
I honestly, I debated about it, too. The powder didn't seem to show any signs of age, but I figured better to be safe than sorry. Tough call, though, I could see it going either way. Maybe next time I'll reduce the charge and reuse the powder...
|October 8, 2012, 10:28 PM
Senior Member
Join Date: November 12, 2005
Posts: 2,536
As long as you know that ammo is from the same case there is no need to down load. Just do what I did.
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The Wayne County Historical Societys "Plain Speaking" series returns this Friday, August 17, to the subject of Wayne County artist Howard D. Becker, whose paintings are currently being featured in a museum exhibit. Two previous presentations featured Becker the father and Becker the personality, and this weeks panel will discuss Howard Becker as artist.
Panelists are Juan H. Espino of Hawley, Thomas Colbert of New York City and Hawley and Charles G. Woods of Honesdale.
Tom Colbert, an Iowa native, earned a master of fine arts degree from the University of Iowa and has exhibited his paintings at galleries in New York City, Florida, Nebraska, South Dakota, New Jersey, Iowa, Hawley and Honesdale, as well as in his studio at his Hawley home. Colbert is a trustee of the Wayne County Historical Society and Chair of the Towpath to Trail Committee that is developing the society's historic property at Lock 31.
Charles G. Woods, a Chicago native, holds degrees in philosophy and religion and is an award-winning architect as well as a prolific painter. A local resident for more than twenty-five years, his paintings have been shown at more than fifteen art shows in the last five years. He is an art critic for a Scranton/Wilkes-Barre newspaper. His work is currently on display at Grand Style Framing Co. Gallery in Honesdale.
Juan H. Espino is a native of Mexico who has lived in Wayne County since 1988. Well-known for his colorful paintings of local scenes as well as his interpretation of national and international events, Espino is the owner of the Looking Glass Art Gallery in Hawley. In addition to exhibiting locally, in 2010 he was invited to exhibit at the Musée International d'Art Naif in Quebec, Canada, and will be showing his paintings at the Capitol building in Harrisburg during the month of October. Espino is also a Trustee and guest curator of the Howard Becker exhibit at the Wayne County Historical Society.
The "Plain Speaking" talks are free and scheduled for Fridays 5-6 pm in the Multi-Purpose Room. For more information and/or a "Plain Speaking" schedule, call the Wayne County Historical Society at 570-253-3240.


text: Vancouver Whitecaps bracing for big leap to top league - Georgia Straight July 31, 200812:00AM PDT Previous Next By Jeff Paterson Much has been said and written about Vancouver's bid to land a Major League Soccer franchise to begin play in 2011. And as sports wagers go, it looks like Vancouver joining the top league in North America is a sure bet. Less clear, however, is exactly what the Whitecaps will be getting themselves into and what they'll be able to provide fans in terms of the level of on-field competition on a regular basis. There's no denying that MLS teams have bigger names and bigger payrolls than teams like the Whitecaps that compete in the United Soccer League's First Division. But is the level of play so much better that the 'Caps will be able to attract 20,000 fans to a Major League Soccer game downtown, instead of the 5,000 loyal fans they have for USL home games at Swangard Stadium? They certainly hope so. And when you look at the 48,000 the Caps attracted for last November's visit by David Beckham and the Los Angeles Galaxy, it's clear there are enough casual soccer fans and stargazers out there to put big crowds in the seats on occasion. Keep in mind that the Whitecaps held the Galaxy to a scoreless draw that night and then beat the Beckham bunch earlier this year in a friendly in Edmonton. The 'Caps also earned a 1-0 victory against Toronto FC on Canada Day, and a week later battled that same MLS club to a 2-2 draw at Swangard. And Montreal, another team currently in the USL, won a three-team round-robin tournament with Vancouver and Toronto to earn the right to represent Canada in the next round of CONCACAF (Confederation of North, Central American and Caribbean Association Football) champions-league qualifying. So there's ample evidence to suggest that United Soccer League teams can hold their own against Major League Soccer sides, and that the gap in talent is far smaller than MLS would like fans to believe. And with expansion franchises in Seattle (next year) and Philadelphia (in 2010) set to join MLS before another round of expansion for 2011—the round expected to include Vancouver—will the talent pool be able to meet the needs of MLS and its newest clubs? Then again, MLS continues to grow in size and scope, and Beckham's arrival may signal the start of a European invasion (or perhaps from other parts of the world), giving more teams access to names with big drawing potential. But even beyond the star power that the United Soccer League cannot provide, MLS appears to be a step up from the echelon on which the Whitecaps are playing. "I think when you strip away everything else, certainly there are four of five players on MLS rosters that perhaps on paper are a level above what we have in USL," the 'Caps director of soccer operations, Bob Lenarduzzi, told the Straight after the club's July 25 announcement that it was submitting a formal application to join Major League Soccer in three years' time. But Lenarduzzi has been around long enough to know that lower-level teams often raise their game when facing more talented clubs. "When it comes down to a competition between the two, it's much like what we find in every other country in the world when it comes to cup play: inevitably the championship teams will knock off the premiership sides," he added. "Now, over the course of a season, can you sustain that? Probably not." If the Whitecaps are granted entry into Major League Soccer in 2011, there will likely be significant carryover from the team that plays in the USL the previous year. But in order to be competitive—and this is a city that has seen championship soccer in the past and likely won't accept too many years of expansion woes—the Whitecaps will have to upgrade their talent base. That's why Lenarduzzi and his staff will be keeping a close eye on the transition in Seattle, where the USL's Sounders will make the jump to MLS for next year. A club that struggles to put 2,500 people in the seats for USL games has already sold 16,000 season tickets for next year. They've been able to convince soccer (and sports) fans in the Emerald City that they're going to the big leagues. And the Sounders will be under the gun to produce. "In the case of Seattle, they're in USL this year, they're going to be in MLS next year, and their roster will likely significantly change from this year to next," said Lenarduzzi. "When you look at our league and the success we've had [against MLS teams], it would appear there isn't a great deal of difference. "But there is that subtle difference that you would see if, in fact, you were playing against that opposition over the course of the season. There's no doubt that MLS is the top level of soccer in North America." Although there have been recent reports that Vancouver Canucks owner Francesco Aquilini is also eyeing an MLS expansion franchise for this city, it would seem the original bid by Lenarduzzi, on behalf of Whitecaps owner Greg Kerfoot and backed by NBA superstar Steve Nash, is the front-runner. MLS is expected to announce its expansion cities for 2011 before its championship game in November. The Whitecaps are confident their bid will be accepted by MLS, just as they believe Major League Soccer will be accepted by the people of Vancouver. If they're correct on both counts, the sport could very well reach levels of popularity not seen here since the glory days of the original Whitecaps, 30 years ago. Previous Next


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TUNIS (Reuters) - At least 200 people were injured as Tunisians demanding jobs and economic development clashed with police on Wednesday, medical sources said, in the latest unrest to hit the country that spawned the Arab Spring uprisings.
Officers fired teargas and rubber bullets to disperse crowds who rallied for a second day in Siliana, a city in Tunisia's economically deprived interior on the edge of the Sahara desert, said witnesses.
Tunisia ousted its president Zain al-Abidine Ben Ali last year, setting off a wave of uprisings that toppled rulers in Egypt, Libya and Yemen and inspired the revolt in Syria.
Its new, elected Islamist-led government has since struggled to revive the economy in the face of a decline in trade with the crisis-hit euro zone and disputes between secularists and Salafi Islamists over the future direction of the North African state.
A medic from Siliana Hospital who did not wish to named said more than 200 people had been injured in the clashes.
A journalist from France 24 television told Reuters he and a colleague had been hospitalized for wounds from birdshot apparently fired by riot police.
Many protesters demanded called for the resignation of local officials, saying the authorities had failed to release development funds for their region.
State television said that at least 80 people were injured and that residents blocked the entrances to the city, setting tires alight on roads.
Iyed Dahmani, a politician from the Republican Party in the town, said the national guard - an interior ministry-run security force - had deployed tanks to help restore order.
The protests were the fiercest since hardline Salafi Islamists attacked the U.S. embassy in Tunis in September over an anti-Islam film made in California. That violence left four people dead.
Prime Minister Hamadi Jebali has accused both Salafis and liberal elites of harming Tunisia's economy and image through their conflict with each other. His Ennahda party has tried to present itself as a middle way between liberals and Salafis.
The World Bank on Tuesday approved a $500 million loan to Tunisia to help it recover from the uprising, with another $700 million loan coming from other donors.
The loan, the World Bank's second since the revolution, aims to support Tunisia's economic recovery by providing funds to improve the business and financial sectors and reform social services.
(Reporting By Tarek Amara; Writing by Tarek Amara and Andrew Hammond; Editing by Andrew Heavens)


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Chief Washakie Scholarship Recipients Selected at UW
Chief Washakie scholarships recently were awarded to 14 University of Wyoming students for the coming academic year.
They will be recognized at the American Indian Studies Honoring of Graduates ceremony at 6 p.m. Friday, May 10, in the Garden Ballroom of the UW Conference Center, located at 22nd Street and Grand Avenue in the Hilton Garden Inn.
New recipients are Caitlin Brown, family and consumer science, junior, Lander; Rain Chippewa, juris doctoral candidate, Fort Washakie; Colleen Friday, environmental and natural resources/rangeland ecology and watershed management, junior, Laramie; and Lorraine Goggles, education, freshman, Lander.
Also, Mia Holt chemistry, sophomore, Lander; Nicola Holt, anthropology, junior, Lander; Franklin Lanier, psychology, sophomore, Riverton; Shane Lawson, elementary education, sophomore, Riverton; Jesse Moss, criminal justice, junior, Arapahoe; and Tacy Thornley, secondary art education, senior, Riverton.
Current recipients of the Chief Washakie Scholarship who will continue to receive support for the coming year are Melvin Arthur, a graduate student in kinesiology and health, Ethete; Kristie Asay, psychology, junior, Riverton; Vittrio Capitan, art (graphic design), junior, Fort Washakie; and Nan Craft, organizational leadership, junior, St. Stephens.
The scholarship program was created in 2003 when the Chief Washakie Foundation gave $200,000 to UW. Funds were collected to create Chief Washakie statues in the United States and Wyoming capitol buildings, and the joint tribal headquarters in Fort Washakie. The gift was matched by the state, creating a $400,000 endowment which annually produces income for the scholarships.
The Chief Washakie Memorial Endowment at UW was established to help students and educators -- with significant ties to the Wind River Reservation community -- gain formal knowledge, skills and abilities.
The selection committee is composed of representatives of the Wind River Reservation community and UW. Members are James Trosper, Chief Washakie Foundation chairman; Mark Harris, co-chairman of the Chief Washakie Foundation; Zedora Enos, great-granddaughter of Chief Washakie; May Raynolds, a Lander resident and member of the Chief Washakie statue committee; Debra Reed-LIttlesun, UW financial aid scholarships associate director; Angela Jaime, UW College of Education associate professor; and Tammy Mack, UW student financial aid scholarships assistant director.
For more information about the Chief Washakie Scholarships, contact Reed-Littlesun at (307) 766-2411 or email email@example.com.


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Building on last year's success, the 2015 Design Automation Conference in San Francisco is offering even more substantial content in the track centered on silicon IP and design reuse. Reading through the list of topics, speakers, and companies set to be featured across a diverse set of sessions from June 7-9 at Moscone Center, two things are obvious.
One, a lot of work has been done to assemble all of this. And two, it's possible the thorny issues surrounding IP reuse may never go away: integration, verifying quality, convincing staff to use design blocks that originate outside of the group, and dealing with the massive amounts of data that IP selection and reuse generates.


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Part of National Museums Liverpool
After a long absence our Claw Club has been re-launched! The Claw Club is a FREE natural history group for 8-11 year olds, held on a Saturday morning each month in World Museum. The club is run by the Bug House and Clore Natural History Centre staff with the help of our very own museum experts.
Here is a taster of some of the sessions we run:
In the summer there will be outdoor field trips to Hilbre Island where we may see grey seals, visits to Sudley House for bug hunts and beachcombing in New Brighton.
How to join:
The club is free to join but places are limited. Our outdoor sessions are also free to attend but please be aware that we cannot provide transport and car parking fees may apply to some sites. Parents are expected to remain with children on field trips.
If all places are currently filled, you will be added to a waiting list. If you would like to join, please complete the membership form below and return to the address shown.
Alternatively you can contact the World Museum information desk on 0151 478 4393 and ask to speak to Bug House staff.
We use cookies to allow you to use parts of the site, to provide extra services such as page translation, to help us analyse how our visitors use the site, and for marketing and advertising purposes. The site includes content and tools provided by third parties, such as social media platforms, who may also use cookies to track your use of this site.
© Copyright 2018


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Smaller Businesses
You are here: Home : Topics A-Z : Smaller Businesses
The Scourge of Performance Reviews
While the purpose of employee assessments is well founded, in practice they invite mismanagement and should be replaced with different performance-enhancement tools.
August 16, 2012
I don't like performance reviews, and I'm not alone. Not that they can't be done well. It's just that, owing to human nature, they rarely are.
Let me count the ways they fall short: (1) Many people, including otherwise good managers, shy away from difficult discussions. (2) The typical numerical grading scheme is so subjective that getting a new manager only to receive a higher or lower grade than before is commonplace. (3) Some managers use reviews as a tool to bully, intimidate, get even with, or stifle the development of their reports. (4) Reviews create much stress in the organization, as managers don't like giving them any more than employees like getting them. (5) These days, employees are often required to assess not only themselves but also their managers, though it's anyone's guess how honest one can be without suffering ill repercussions. Read more...
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Private Company Pessimism Grows
A new report on privately held growth companies says they–re uncertain about European and U.S. economies, the fiscal cliff, new financial regulations, and global warming. (No, not global warming. But the other stuff, yes.) August 14, 2012
How to Shore Up the "People" Part of Supply-Chain Performance
The success formula includes crystal-clear processes, input from the right people to drive engagement in following those processes, and ongoing learning by doing. August 8, 2012
Is This Pay Package Good Enough?
Job-hunting CFOs may have an innate sense as to whether a compensation offer feels right, but how can they know for sure? Here are some tips for getting comfortable with the decision. July 30, 2012
Stories of Demise of Health Coverage Are Exaggerated
Deloitte research shows that 9% of employers expect to eliminate health benefits within three years. But that result isn–t nearly as sensational as many reports on the research implied. July 26, 2012
Will Big Companies Drop Health Benefits?
Once the dust settles on the forthcoming state insurance exchanges, small companies may not be the only ones seeking to shed employee health plans. July 12, 2012
Investing in Interns Can Produce More Than Interim Benefits
How businesses can use internships – paid and unpaid – to boost short-term productivity and lay a foundation for long-term growth. July 2, 2012
Stunned CFOs Now Must Focus on Complying with Health-care Act
The Supreme Court opinion was not the one most of them wanted. But now finance chiefs need to work on compliance and make some tough decisions. June 28, 2012
No Escaping Cyber Risk, Companies Warned
Virtually all organizations are prone to data breaches, which, according to recent research, cost an average of $5.5 million each. June 26, 2012
Top 10 Trends in Executive Job Market
A quarter of companies are expected to add executive positions in 2012, says networking group ExecuNet. May 21, 2012
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"World Court Judge Joan Donoghue"
The judge is the first female American to sit on the court, which is in The Hague, Netherlands. Donoghue discusses the role of the court and her work on it with host Marcia Franklin. G
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Ashlee Lyn Waterman engaged to Benjamin Dictor
Joseph and Ann-Marie Aguire of Warwick are pleased to announce the engagement of their daughter, Ashlee Lyn Waterman, to Benjamin Dictor, son of Ronald Dictor of Wheaton, Ill. and Debra Dictor of Plainfield, Ill.
After graduating from Warwick Veterans Memorial High School, Ashlee served our country in the United States Navy, eventually settling in Colorado, where she currently resides with Ben, originally from Illinois.
An August 2012 wedding is planned.
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A Different Life
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Brassed Off, directed by Mark Herman and released in
1996, stars Pete Postlethwaite, Tara Fitzgerald, Stephen Tompkinson
and Ewan McGregor. Strangely marketed as a comedy, this film tells
the very moving story of impending mass redundancies in Grimley, a
Yorkshire mining town, when its profitable colliery is threatened
with closure.
It is set in 1992, at a time of great change in the coal
industry, and chooses to focus on the lives of the miners who play
in the Grimley Colliery Brass Band. The band is led by their
passionate conductor Danny, who is determined to take the group to
the finals of the National Championships at the Albert Hall. The
late Pete Postlethwaite plays Danny, in one of his most acclaimed
performances. This film was said to have played a part in the
inspiration for The Coalfield Regeneration programme set up in the
late 1990s to improve the quality of life in Britain's coalfield
The opening scene shows us some miners
finishing a shift at the coalface before transforming into cleanly
scrubbed workers clocking off. We first meet the all male group of
musicians soon after that at their rehearsal where they are joined
by a young woman called Gloria, who is visiting Grimley, and turns
out to be the grand daughter of a former member of the band. An
exception is made to the all male constitution of the band by
allowing her to join them, after an audition in which she proves
that she will be an asset to them in their quest to win the
National Championships.
A love interest develops between Gloria and a
young man in the band called Andy, which provides one of several
storylines, as it becomes clear that Gloria's presence in the town
has something to do with the potential closure of Grimley's
coalmine. Through the following scenes, the film introduces us to
the respective families and partners of each of the main members of
the band and we come to understand the precarious financial
predicament that some of them are in as they contemplate
As Brassed Off progresses, the miners
are offered a very favourable redundancy package by management,
which many can't resist and when a majority vote to accept the
deal, pit closure becomes inevitable. One of those accepting the
offer is Danny's son, Phil, who is the trombonist in the band. He
is already struggling to survive as a result of debts he accrued
from the lengthy strike action he took ten years earlier. We watch
him develop depression as he struggles to provide for his wife and
four children. Unable to share his problems with anyone, he
struggles to earn money as a children's entertainer called Mr
Chuckles. His serious financial predicament only comes to light
with the arrival of two moneylenders at his front door, who demand
the immediate payment of his debts before taking all of the
possessions from his home. As a result, his wife leaves, taking the
children with her, because she can no longer cope with such an
impoverished life. At this point, Phil finds himself completely
alone, having lost his job, his wife, his children and the contents
of his house. When his father collapses in the street and is
admitted to hospital with coal related lung disease, Phil attempts
The miner's band seems likely to collapse
after these events but doesn't and they manage to keep the hope of
National Championships alive as they struggle to hold on to their
self esteem and community identity through their music, at the same
time as contemplating a period of great personal uncertainty.
Brassed Off provides an ideal platform to discuss the
effects that job insecurity and involuntary redundancy can have on
the mental health of individuals and their families. Using the
example of Phil and his family, the film provides us with an
unfolding case history in which to consider the precipitating
triggers for his depression and attempted suicide. It also provides
an opportunity to reflect on the role of purposeful goal directed
activity, both paid and unpaid, in maintaining an individual's self
esteem and self worth.
In the current economic climate in which there
are, once again, threats of large-scale job losses, Brassed
Off's themes may be as pertinent to our society now as it was
in the 1990s. With the recent announcement that the pharmaceutical
company, Pfizer, is to close its R&D establishment in Sandwich,
Kent, where 2,400 jobs will be lost (Guardian
newspaper; 1st February 2011), there is concern about
the effect that this will have on the town and its surrounding
area. A whole infrastructure has grown up to cater for the staff
and their families at the Pfizer plant and local groups talk of
devastation to the surrounding environs when the facility closes.
In a very direct way the issues portrayed in the film are relevant
to the community in Sandwich.
An editorial in the March 2011 edition of the
British Journal of Psychiatry by Dunlop and Mletzko
entitled Will current socioeconomic trends produce a depressing
future for men? ( BJPsych 2011 198, 167-168) discusses the
topic some have called 'Mancession', reminding readers that
approximately 75% of jobs lost since the beginning of the recession
in 2007 were held by men. This is because the construction and
manufacturing industries have been disproportionately affected by
redundancies in the past few years.
An article entitled Job insecurity,
socio-economic circumstances and depression by Meltzer H,
Bebbington P, Brugha T; Psychol Med 2010 Aug (40(8):
1401-7) considers the topic of job insecurity in
the context of the current economic difficulties in the UK and
concludes that job insecurity has a strong association with
feelings of depression in the people that they studied.
An interesting editorial in the BMJ from 2009,
reviews the topic of Unemployment and Health (BMJ
2009; 338:b829). Written by Danny
Dorling, professor of human geography, the article discusses the
effects of mass unemployment on physical and mental health by
reflecting on past epidemics and highlights how young adults, in
particular, are affected. These topics are all brought to life by a
viewing of Brassed Off and the film is surely relevant to
all mental health professionals, as well as those working in
primary care, as the UK faces a period of time characterised by
spending cuts and rising unemployment.
For more specific advice on how to approach
the consequences of losing ones job, the NHS choices website has an
short video called 'coping with redundancy',
as well as plenty of other information on managing the health
consequences of threatened or actual job loss.
Minds on Film is written by Dr Joyce Almeida.
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Minds on Film is a monthly blog that explores
psychiatric conditions and mental health issues as portrayed in a
selection of readily available films.
Please note that this blog may contain
plot spoilers. Any views expressed are purely my own.


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It was heartbreak for Vancouver Whitecaps FC central defender Carlyle Mitchell on Sunday as his Trinidad & Tobago were beaten 1-0 in extra time by Cuba in the final of the 2012 Caribbean Cup in St. John's, Antigua and Barbuda.
HIGHLIGHTS: //www.youtube.com/watch?v=3t5a1JlCceU
It was a strong tournament overall for the 'Caps central defender, as Mitchell played every minute of the tournament for his country and converted from the spot in Friday's semifinal penalty kick win over Martinique.
In Sunday's final, Mitchell almost broke the deadlock in the ninth minute when his header hit the crossbar.
Cuba survived and despite missing a penalty in the 61st minute, the Lions of the Caribbean secured their first ever Caribbean Cup when Marcel Hernandez scored in the 22nd minute of extra time.
Despite the loss, the Soca Warriors are guaranteed a spot in next year's CONCACAF Gold Cup.
Meanwhile, it was a disappointing tournament for highly-fancied Jamaica and Whitecaps FC striker Darren Mattocks.
Mattocks came on as a 53rd minute substitute in the Reggae Boyz' shock 2-1 loss to French Guiana on December 8 in their opening group game.
Mattocks then started and played the full 90 minutes of Jamaica's remaining matches– a 0-0 draw with Martinique and a 1-0 defeat to eventual Caribbean Cup winners Cuba.


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Ever since "Ace Ventura: Pet Detective", Carrey has been widely known as a comedian. After Ace Ventura, he continued his comedic routes with such films as "The Mask", "Dumb and Dumber" and an Ace Ventura sequel. He was the king of comedy and a guy that studios wanted.
His next project proved that people were not ready for any change from their funnyman. "The Cable Guy" would mark his first 20 million dollar paycheck and his first film that would confuse many critics and fans. People didn't like the fact that Carrey played a dark character who was the antagonist. As the movie has aged though, some now regard it to be one of his better comedies.
He responded with his next movie, "Liar Liar". It was a return to old in this slapstick comedy, where he could not tell a lie for 24 hours. The film received outstanding reviews, with critics calling it his best comedy. It also made a big splash at the box office. However, Carrey would surprise audiences with his following roles.
His next film, he played the role of a man who doesn't know he's living in a constructed reality soap opera, being televised to billions across the globe. "The Truman Show" would prove to be Carrey's best-reviewed film, averaging a 95% at Rotten Tomatoes. Some Critics compared the performance to Tom Hanks in "Forrest Gump", with many others surprised by the strong performance.
"The Truman Show" would earn Carrey's first Golden Globe Award for Best Performance by an Actor in a Drama, and he showed no signs of slowing down either.
Carrey continued to show his range of acting with his next films "Man on the Moon", "The Majestic", and "Eternal Sunshine of the Spotless Mind". He proved that he was not just a comedian, or did he.
After he teamed up for the second time with director Joel Schumacher, some critics and fans thought he should stick to his Comedies. However, many thought "The Number 23"'s failure was largely Schumacher's fault, saying, 'with a better director it could have been better'. "The Number 23" went on to score an 8% on Rotten Tomatoes, becoming Carrey's worst critically received film to date.
His next film, coming soon, is arguably his toughest role to date. Based on the true story, Carrey plays as Steve Russell, a homosexual con artist who is resilient to lose the love of his life, Phillip Morris, and goes to extremes to reunite with him. "I Love You Phillip Morris" is already receiving great buzz out of Sundance Film Festival and European Film Festival, being called 'Carrey's best film since Eternal Sunshine of the Spotless Mind' and 'one of Carrey's best performances'
Unfortunately, the debate that 'Carrey should stick to comedies' will most likely always be there. However, don't expect that to stop him from exploring new-interesting roles.


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Ted Schutz, 80 - March 26, 2008
Ted Schutz, 80, of Elwood, died Wednesday, March 19, 2008, at Gothenburg Memorial Hospital.
Services were held on Saturday, March 22, at Our Redeemer Lutheran Church in Elwood with the Rev. Jeff Ernstmeyer officiating. Burial took place at the East Salem Cemetery southwest of Elwood.
Schutz was born on Nov. 10, 1927, at Gosper County to Richard and Josephine (Heny) Schutz. He attended Salem Lutheran Parochial School.
On May 2, 1948, he was united in marriage to Janet Umberger at the Methodist Church in Elwood. The couple made their home southwest of Elwood where they farmed and raised livestock until moving to Elwood in 2000.
He was a lifetime member of the Salem Lutheran Church as well as Our Redeemer Lutheran Church at Elwood. He was also a past member of the Elwood Public School Board.
Schutz enjoyed spending time with his grandchildren as well as attending rodeos and traveling, according to family members.
He was preceded in death by: his father, Richard Schutz; two step-fathers—Frank and Emil Jorges; three brothers—Robert, Paul and Kenneth; a sister, Nora June Lehmann.
Survivors include: his wife, Janet Schutz of Elwood; four sons—Scot (Cindy) Schutz, Steve (Nancy) Schutz and Stanley (Rhonda) Schutz, all of Elwood, and Clay (Janet) Schutz of Grand Island; a daughter, Jane (Bob) Hilton of Elwood; thirteen grandchildren—Anthony (Cori) Schutz of Lincoln, Tiffany (Bodie) Weeder of Minden, Danielle Schutz of Lincoln, Grant Schutz and Stephen Schutz of Elwood, Lisa (Naeson) Halker of Gretna, Lori (Ryan) Shutts of Sidney, Jason Schutz of Elwood, Amy (Rob) Czaplewski of Grand Island, Eric (Jami) Hilton of Eagle, Perry Schutz, Levi Schutz and Maddie Schutz, all of Grand Island; nine great-grandchildren—Angelina and Berlyn Schutz, Payton and Hudson Weeder, Remington and Bellamy Halker, Aidan Shutts, Jenna Czaplewski and Nevayla Hilton; sister, Elmyra Wolf of Arapahoe; sister-in-law, Esther Kaup of Elwood; numerous other relatives and friends.
A memorial has been established.
Online condolences may be shared at berrymanfuneralhome.com.
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Hayden Panettiere Confirms Engagement to Wladimir Klitschko, Shows Off Ring!
Hayden Panettiere shows off her large engagement ring while stepping out for her interview at the Good Morning America studios on Wednesday (October 9) in New York City.
The 24-year-old actress confirmed her engagement to her longtime love Wladimir Klitschko during her interview later during Live! with Kelly & Michael.
Host Kelly Ripa pointed out the ring on her left hand, to which Hayden replied: "I think it speaks for itself." Kelly then further asked for confirmation if she was engaged and she replied, "I am."
FYI: Hayden is wearing a Givenchy jacket, Mugler pants, and Saint Laurent boots.
Congrats to the happy couple!!!


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MOUNTAIN VIEW, Calif., -- February 12, 2002 -- Synopsys Inc. (Nasdaq: SNPS) and Artisan Components, Inc. (Nasdaq: ARTI) today announced that Artisan's SAGE-X™ 0.18- and 0.13-micron family of standard cell libraries are now qualified and immediately available for Synopsys PrimeTime® SI. With PrimeTime SI and Artisan's SAGE-X libraries in their nanometer design flow, customers are able to pinpoint crosstalk-induced timing problems quickly, thereby reducing the risk of potential chip failures.
PrimeTime® SI is a full-chip, static crosstalk analysis tool that detects and isolates signal integrity effects found in designs using 0.18-micron technology and below. PrimeTime SI extends the proven static timing techniques of the industry-leading PrimeTime tool to include crosstalk analysis, delivering a fully integrated solution that is easy to adopt. To help the adoption, Artisan has enhanced its library characterization tool around Synopsys characterization guidelines to generate Liberty™ (.lib) libraries that are fully qualified for PrimeTime SI.
Artisan's SAGE-X Standard Cell Libraries are optimized for density and speed and have an enhanced cell set designed to generate superior RTL-to-GDSII results through optimization for state-of-the-art electronic design automation (EDA) tools and flows. The libraries contain 535 cells and 130 functions and include a rich set of combinatorial and sequential functions; ultra high-performance, high-density arithmetic cells; register file support via high-density 'bit cells'; scan flip-flops for design-for-testability support; and integrated clock gating cells for power optimization support.
To facilitate library qualification, Synopsys provided Artisan with a correlation kit consisting of a library screener and characterization guidelines for PrimeTime SI. Working together, Synopsys and Artisan verified that the libraries - when tested with PrimeTime SI - met the characterization guidelines and offered SPICE-level accuracy.
"To avoid costly respins, customers moving to 0.13-micron design need to analyze their SoC designs for potential crosstalk-related timing failures," said Dhrumil Gandhi, senior vice president of product technology at Artisan Components, Inc. "To address this need, we have enhanced our library modeling tools around Synopsys' characterization guidelines, enabling us to generate Liberty (.lib) libraries that are fully qualified for PrimeTime SI. As a result, our customers can adopt PrimeTime SI for static crosstalk analysis in their designs."
"Advanced library modeling for nanometer design continues to be a key focus of our Synopsys/Artisan alliance, as demonstrated by the qualification of Artisan Libraries for PrimeTime SI," said Antun Domic, senior vice president and general manager of Synopsys' Nanometer Analysis and Test Group. "Synopsys and Artisan now offer easy access to high-quality libraries for PrimeTime SI, enabling our customers to perform fast, accurate gate-level crosstalk analysis on their system-on-chip designs."
About Artisan Components
Artisan Components, Inc., (Nasdaq: ARTI) is a world leader in intellectual property (IP) components, providing high-quality solutions for many of the world's leading semiconductor foundries, integrated device manufacturers, ASIC vendors and IC design teams. Artisan's Process-Perfect™ memory generators, standard cell and I/O libraries are optimized to achieve the full-speed, density and low-power potential of each semiconductor process. Each product is verified using the industry's most comprehensive QA and validation procedures and delivered ready to use with a complete set of views and models supporting leading design tools. Artisan's headquarters are located at 141 Caspian Court, Sunnyvale, CA 94089-1013.
About Synopsys
Synopsys Inc. (Nasdaq:SNPS), headquartered in Mountain View, Calif., creates leading electronic design automation (EDA) tools for the global electronics market. The company delivers advanced design technologies and solutions to developers of complex integrated circuits, electronic systems and systems-on-a-chip. Synopsys also provides consulting and support services to simplify the overall IC design process and accelerate time to market for its customers. Visit Synopsys at http://www.synopsys.com.
Safe Harbor Statement
This press release may contain forward-looking statements, including, without limitation, statements regarding the performance and capability of Synopsys' PrimeTime SI and Artisan's qualified libraries and general market acceptance of such products. These statements are subject to various risks and uncertainties, including, but not limited to, deployment delays, industry resistance, product capability and performance, revenue recognition and collection, demand for semiconductors generally and end user products that incorporate semiconductors, and general economic conditions. We refer you to the documents that Artisan and Synopsys file from time to time with the Securities and Exchange Commission, in particular their respective annual reports on form 10-K and quarterly reports on form 10-Q.
Artisan Components is a registered trademark and Process-Perfect is a trademark of Artisan Components, Inc. All other trademarks or registered trademarks are the property of their respective owners.


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Zachman Enterprise Architecture: Modelling Workshop Zachman Certification
News • Dec 24, 2013 14:02 GMT
Zachman Enterprise Architecture: Modelling Workshop Zachman Certification
John Zachman and Sunil Dutt Jha
29th September - 2nd October 2014, London
This newly revised four day seminar and workshop, based on the recently released Zachman Framework V3.0, for the first time incorporates actual modeling experience. The modeling workshop is based on actual Enterprise experience and is designed to give the participants hands-on experience creating both "Primitive" (architecture) models as well as "Composite" (implementation) models. The seminar and workshop will prepare delegates for both levels of the Zachman Certified- Enterprise Architect program: Zachman Certified™ - Enterprise Architect Associate Level 1 and Level 2.
Learning Objectives
A sense of urgency for aggressively pursuing Enterprise Architecture
A comprehensive definition (description) of Enterprise Architecture
Differentiation of Enterprise Architecture from Systems Implementation
Creating Enterprise Strategy Models which form the basis for Enterprise Architecture
Differentiation of Ontology from Methodology
Utilizing Enterprise Architecture for operational decision making
A strategy for reducing "time-to-market" for systems implementations to virtually zero
Strategy for integration beyond jurisdiction (Interoperability)
Architectural Principles for meeting enterprise requirements
Ensuring traceability across the artifacts for impact analysis and change management
BPM, SOA, BI, MDA, ITIL, etc. in the context of the Zachman Framework


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There's a good kind of pain that comes with age. It's the aches in my knees, hips and ankles that I get from sitting in a tree stand too long. Yeah, I realize that sounds kind of weird, but that first tree-stand vigil of the year always leaves me basically crippled. Joints pop, tendons hurt and muscles ache.
But I love it. Absolutely love it.
As Deer & Deer Hunting freelance videographer Nate Winters and I climbed into the first stand of the year, we obviously had high hopes. Our host, Mark Schuh of Schuhter's Outpost already had provided us with visual proof that several nice bucks were using the oak and hickory draw where we would be hunting.
Although I've hunted this part of my home state numerous times, I must admit that this trip was markedly different. The topography was the same, but the outfitter's approach was much different. Schuh is all about low-pressure hunting, which means he highly discourages morning hunts during the early season. The rationale for that is simple: It is difficult, if not impossible, to hunt this area's bluff country in the mornings without spooking deer on your way to the stand.
Schuh started his venture five years ago when he saw a special opportunity to provide a niche service that was going to change the way people experience quality whitetail hunts in two states (Wisconsin and Minnesota) from one location. Through countless hours of hard work, planting food plots, scouting land, and studying whitetail behavior, Mark began to create a hunter's paradise. With the help of landowners, family, friends, and neighbors, Schuhter's Outpost began building its name and reputation.
He started by remodeling an old granary shed into a full service rustic hunting cabin, while retaining the traditional "hunting shack" atmosphere. He spent countless hours in the field observing, scouting, and preparing hunting properties for clients who demand the absolute best. The deadly combination of quality management, strategic food plots, waterholes, stand-locations (and access to them) has created top-notch trophy whitetail hunting.
Schuhter's Outpost now has access to nearly 2,500 acres of intensely managed property in the heart of Buffalo County and Southeastern Minnesota's finest whitetail habitat. Every year the quality of bucks and hunting goes up.
For our hunt last weekend, the temperatures were warm, but not unbearable. It seemed almost too early in the year to be hunting, but every September archery opener feels like this. I guess it just takes a few cold nights to flip that switch fully to "beast mode" for us diehard bowhunters.
With my safety harness secured and Mathews Heli-M hoisted to my lap, it's time to sit. And wait. And hope. And dream. We might see a deer this afternoon, and we might not. Doesn't matter, because we're hunting. Let the season begin. Whitetail season is upon us, and I honestly can't think of a better place to watch the sun go down than from this glorious perch high above the forest floor.
This is a five-part series. Previous posts:
1. Bowhunting in Buffalo County, Wisconsin
2. Getting Dialed in to Hunt Big Bucks
3. Today: Bow Season Starts in Corn Country
Up next: Checking out a bona fide 170-class typical 10-pointer.


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Mass. police dog accidentally fires stolen Manchester gunBy BENJAMIN C. KLEIN
Union Leader Correspondent
March 04. 2013 7:12PM
LAWRENCE, Mass. - No one was injured when a police dog searching for a handgun stolen from New Hampshire managed to fire the weapon with its paw Saturday morning in Lawrence.
Ivan, a 3-year-old German shepherd, and his handler, Lt. John Pickles of the Essex County Sherriff's Department, were startled when a gun Ivan was searching for in a snowbank fired when he pawed at it to indicate its location.
Essex County Sheriff's Department spokesman Maurice Pratt said the department was called in by the Lawrence Police Department for help locating a weapon after a man was seen burying something in the snow by police after a report of shots being fired.
After the gun was recovered, Detective Tom Cuddy of the Lawrence Police Department said police matched it to a gun that was stolen from Manchester on Oct. 2 of last year.
Pratt said Ivan, who is one of the department's 18 K-9s, has been with the department about a year and is narcotics and search trained.
"Ivan is trained to sit when he finds something, then the handler will instruct him to paw for the item, and that is when the gun fired," Pratt said.
While the round that was fired has not been located, Pratt said, "The most important thing is that the dog, officer and civilians are fine. We are fortunate no one was hurt."
Despite the scare, Pratt said Lt. Pickles and Ivan would not miss any time due to the incident.
"We sure have not heard of anything like this ever happening," he said.
While a police dog firing a gun he was searching for might be new, there are media accounts of man's best friend accidentally firing off a few rounds.
In November 2011, a duck hunter in Utah was injured when his dog jumped on the bow of a boat and discharged a shotgun into his owner's backside. Last week, a Florida man was shot in the leg while driving when his excited dog, who was jumping around inside a truck, hit an unsecured gun and caused it to fire.


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- Contact:
- firstname.lastname@example.com
Aaron Byrd has always had a desire and curiosity to seek out new experiences, people, places and, most of all, music. Having visited 17 countries (so far) and spending at least three hours a day listening to new music, it's safe to say music and travel are his biggest passions in life.
His attraction to the unknown and thirst for discovery has fueled an eclectic and expansive taste in music, from the underground hip hop scene the LA native explored as a teenager to his love of Guaguanco from Cuba.
An Engineering major at UCLA, it's not surprising that he likes to dig into the roots of where things begin, from tango to trip hop. He fuses musical connections across all borders, boundaries and timelines because what he looks for is more than a catchy beat.
"I see music as an extension of human emotion and the songs I am drawn to most have a subtle sense of euphoria. Something that is not overwhelmingly bold, but undeniably powerful."
Byrd learned his DJ skills from the best of them – KCRW's own Garth Trinidad. He became a loyal fan of the station while in college and, after paying his dues as a volunteer at the front desk, he found a mentor in Trinidad while working in the studio during his show.
Since his start at KCRW in 2007, Byrd has appeared on the front page of the New York Times and in both the LA Times and LA Weekly. He is called on to curate a wide range of events around town, from post-performance events at the LA Opera to a weekly live performance series at a boutique West Hollywood hotel.
As a DJ, Byrd has opened for Groove Armada, James Blake, Fat Freddy's Drop, Little Dragon, and Jose James and is regularly featured at clubs around town.


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This is the third in a series of blogs describing conversations with small companies that exhibited at 2012 Design Automation Conference in San Francisco, June 4th to 6th.
Since I published the Monday@DAC and Tuesday@DAC blogs, both Dan Nenni and Mike Demler have published attendance numbers for the conference. Interesting that the two sets of numbers see the same cup as either half-full or half-empty.
Per Nenni, the cup's half-full when comparing DAC 2011 in San Diego to DAC 2012 in San Francisco: "Conference attendees were up to 1901, up 9% on last year. But exhibits only passes were way up to 2783, an increase of 39%. Even booth staff was up 11% to 2704."
Per Demler, however, the cup's half-empty when comparing DAC 2009 to DAC 2012, both in San Francisco: "Conference attendees remained essentially flat compared to the last San Francisco DAC, at 1,962 in 2009 versus 1,902 this year. Exhibit-only attendees dropped by nearly 20%, from 3,337 three years ago to 2,703 in 2012. It is interesting to note that Booth Staff actually increased slightly, from 2,697 to 2,704."
Demler added: "An analysis of the DAC exhibitor list reflects many of the changes that have occurred in the industry. Fewer than 100 companies on the show floor, approximately half of the exhibitors, actually develop design tools."
Demler also observed that PDF Solutions, a company whose CEO is on the EDAC Board, did not exhibit at DAC 2012. PDF Solutions does not consider itself a design tool company, however – see my interview with John Kibarian here – so even had the company exhibited that may not have alleviated concerns.


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**1/2 (out of four)
If nothing else, I'll remember "The Iceman" as the movie that dared to cast David Schwimmer in a supporting role as a mustached, ponytailed killer. And the former Chicagoan handles himself just fine.
Otherwise, this true-life story of a bad man who almost never feels bad about what he does lingers in the middle ground between grungy entertainment and a biopic that doesn't illuminate its subject. In 1964 New Jersey, Richie (Michael Shannon, another former Chicagoan) seems like a charming-enough guy. He tells his date, Deborah (Winona Ryder), that she's "a prettier version of Natalie Wood" and balances a spoon on his nose. Yeah, his description of his family is, "My sister and brother are out there somewhere, I guess," but again, he balances a spoon on his nose! Gotta be a good guy.
Actually, he's someone who'd slit your throat for giving him lip and spent years upping his body count with assignments from crime boss Roy Demeo ("Goodfellas' " Ray Liotta, who knows about recruiting someone into the biz). "The Iceman" doesn't need to over-explain how Richie kept his secret life secret while married to Deborah and raising their two daughters, but it seems safe to assume the hitman lifestyle would have a hitch or two that would wind up generating suspicion from the family. Whether it is lateness or blood on a shirt or something—director/co-writer Ariel Vromen should have identified how Richie worked under the radar for so long, not just from the authorities but from the only people in the world he cares about (who think he's in "currency exchange").
It's not clear why Richie's love for his own family doesn't translate to any sympathy for other families, outside of his refusal to hurt women and children. He kills because he's good at it and needs the money, and the moral consideration pretty much ends there. Snippets of backstory add little.
Still, "The Iceman" resists deriving fun from murder like "Pain and Gain," and few actors do the menacing stare like Shannon. "The Iceman" thrives on that scowl, from the cold, flinchless gaze when Roy first puts a gun in his face to his fearless work with his unexpected partner Mr. Freezy (Chris Evans). That Richie's temper eventually bubbles over unsettles less than his chilling, short-term patience when Marty (James Franco in a surprising, one-scene part) prays for his life. "You think God will come down and save you?" Richie asks, willing to wait and see. Take a guess who wins that bet.
Watch Matt on "You & Me This Morning," Friday at 6:55 a.m. on WCIU, the U
Want more? Discuss this article and others on RedEye's Facebook page.


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Phase II Study of Vandetanib in Individuals With Kidney Cancer
|The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
|ClinicalTrials.gov Identifier: NCT00566995
Recruitment Status : Completed
First Posted : December 4, 2007
Results First Posted : March 11, 2015
Last Update Posted : April 7, 2015
- Study Details
- Tabular View
- Study Results
- Disclaimer
- How to Read a Study Record
This study will examine the effectiveness of an investigational drug called ZD6474 (also known as vandetanib or ZACTIMA). Vandetanib is an experimental drug that is designed to prevent the growth and development of new blood vessels on tumors and to prevent the direct growth of cancer cells. It has been tested in a number of clinical trials on adults with cancer, but the United States (U.S.) Food and Drug Administration has not specifically approved it as a cancer treatment. The purpose of this investigational study is to better understand how vandetanib affects humans who have kidney cancer related to von Hippel-Lindau (VHL) disease, and to develop tests that may improve researchers understanding of kidney cancer and its effects.
Volunteers must be at least 18 years old and must have been diagnosed with kidney cancer related to VHL. Candidates must have a life expectancy greater than three months and must have at least one measurable renal tumor for study purposes. Candidates may not be receiving any other investigational agents or have been treated with an investigational drug within the past four weeks. Candidates who have had surgery, chemotherapy, or radiotherapy within the past four weeks will be excluded from the study. Candidates will be screened with a physical examination and medical history.
During the study, participants will receive an oral dose of vandetanib once a day for 28 days (a treatment period known as a cycle). Participants will need to return to the National Institutes of Health every two weeks on the same day of the week as the first dose of vandetanib for a series of tests and procedures, including blood and urine tests and an electrocardiogram. Every 12 weeks, computerized tomography (CT) or magnetic resonance imaging (MRI) scans will be done to assess the size of participants tumors. Participants whose tumors do not grow and who do not have unacceptable side effects may continue to receive vandetanib to maintain the current condition, until researchers conclude the study....
|Condition or disease
|Renal Cancer Von Hippel Lindau
|Drug: ZACTIMA (Vandetanib) (ZD6474)
|Phase 2
Show Detailed Description
|Study Type :
|Interventional (Clinical Trial)
|Actual Enrollment :
|37 participants
|Intervention Model:
|Single Group Assignment
|None (Open Label)
|Primary Purpose:
|Official Title:
|A Phase 2 Study of ZD6474 (Vandetanib) in Patients With Von Hippel Lindau Disease and Renal Tumors
|Study Start Date :
|November 2007
|Actual Primary Completion Date :
|June 2014
|Actual Study Completion Date :
|March 2015
Experimental: Vandetanib in Participants with Kidney Cancer
300 mg/day (starting dose) oral dose of vandetanib once a day for 28 days
Drug: ZACTIMA (Vandetanib) (ZD6474)
- Overall Response Rate. [ Time Frame: cycle 3, day 28 ]Overall response rate is defined as the percentage of participants with either a partial or complete response occurring at any time after initiation of therapy. Response is determined by the Response Evaluation Criteria in Solid Tumors (RECIST). Partial response (PR) is at least a 30% decrease in the sum of the longest diameter (LD) of target lesions, taking as reference the baseline sum LD. Complete response (CR) is a disappearance of all target lesions. Progressive disease (PD) is at least a 20% increase in the sum of the LD of target lesions, taking as reference the smallest sum LD recorded since the treatment started or the appearance of one or more new lesions. Stable disease (SD) is neither sufficient shrinkage to qualify for PR nor sufficient increase to qualify for PD (progressive disease), taking as reference the smallest sum LD since the treatment started.
- Number of Participants With Adverse Events [ Time Frame: 72 months and 14 days ]Here is the number of participants with adverse events. For a detailed list of adverse events, see the adverse event module.
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies.
|Ages Eligible for Study:
|18 Years and older (Adult, Older Adult)
|Sexes Eligible for Study:
|Accepts Healthy Volunteers:
Patients must satisfy all the following criteria to be eligible for study enrolment.
Clinical diagnosis of von Hippel Lindau disease.
The presence of at least one measurable (as defined by RECIST) renal tumor (renal cell carcinoma (RCC)). Patients with tumors localized to the kidney as well as those with metastatic RCC are eligible.
Age greater than or equal to 18 years.
Life expectancy greater than 3 months
Performance status Eastern Cooperative Oncology Group (ECOG) 0-2.
Patients must have normal organ and marrow function as defined below: white blood cell (WBC) count greater than or equal to 3,000micro/L, absolute neutrophil count greater than or equal to 1,500 micro/L platelet count greater than or equal to 100,000 micro/L, serum creatinine less than or equal to 1.5 times upper limit of reference range or measured 24 hr. creatinine clearance greater than or equal to 50 ml/min, aspartate aminotransferase (AST) and alanine aminotransferase (ALT) less than 2.5 times upper limit of reference range, total bilirubin less than 1.5 times upper limit of reference range (less than 3 times upper limit of reference range in patients with Gilberts disease), alkaline phosphatase less than or equal to 2.5 times upper limit of reference range (or less than or equal to 5 times upper limit of reference range if considered to be related to liver metastases by the principal investigator (PI)).
No history of serious intercurrent medical illness.
At least four weeks from completion of any other surgical or investigational therapy for von Hippel Lindau and at least 4 weeks from any major surgical procedure. In addition, patients who have undergone recent major surgery should have well healed surgical incisions.
All men and women of childbearing potential must use effective contraception.
Negative pregnancy test in female patients of childbearing potential within 7 days prior to enrolment on study
Ability to understand and the willingness to sign a written informed consent document.
Prior or concomitant non-von Hippel Lindau associated malignancy with the exception of adequately treated basal or squamous cell carcinoma of the skin, cervical carcinoma in situ or any other malignancy from which the patient has remained disease free for more than five years.
Known brain metastases (unless adequately resected or irradiated with no evidence of recurrence for at least 6 months).
Patients who have had chemotherapy or radiotherapy within 4 weeks prior to entering the study or those who have not recovered from adverse events (to less than or equal to grade 1 Common Terminology Criteria in Adverse Events (CTCAE) v3.0) due to agents administered more than 4 weeks earlier.
Patients may not be receiving any other investigational agents or have received treatment with a non-approved or investigational drug within 4 weeks prior to Day 1 of study treatment except those used for imaging studies.
Use of 5HT-3 antagonists because of the potential effect on corrected QT interval (QTc) interval.
Any concurrent medication that may cause QTc prolongation or induce Torsades de Pointes.
Concomitant medications that are potent inducers of cytochrome P450 3A4 (CYP3A4) function, such as rifampin, rifabutin, phenytoin, carbamazepine, barbiturates such as phenobarbital, or St. Johns Wort.
Clinically significant cardiac event (including symptomatic heart failure, myocardial infarction or angina) within 3 months of entry or presence of any cardiac disease that in the opinion of the Principal Investigator increases the risk of ventricular arrhythmia.
History of clinically significant arrhythmia [including multifocal premature ventricular contraction (PVC), bigeminy, trigeminy, ventricular tachycardia] that is symptomatic or requires treatment (CTCAE grade 3) or asymptomatic sustained ventricular tachycardia
Uncontrolled atrial fibrillation. Atrial fibrillation controlled on medication is not excluded.
Presence of Left bundle branch block.
Previous history of QTc prolongation while taking other medications that required discontinuation of that medication.
Congenital long QT syndrome or first degree relative with unexplained sudden death under the age of 40 years QTc with Bazetts correction that is unmeasurable, or greater than or equal to 480 msec on screening electrocardiogram (ECG). If a patient has QTc greater than or equal to 480 msec on screening ECG, the screen ECG may be repeated twice (at least 24 hours apart). The average QTc from the three screening ECGs must be less than 480 msec in order for the patient to be eligible for the study). Patients who are receiving a drug that has a risk of QTc prolongation are excluded if QTc is greater than or equal to 460 msec.
Potassium concentration less than 4.0 mEq/L, calcium (ionized calcium or adjusted for albumin), or magnesium concentrations outside normal limits despite optimal supplementation/correction
Left ventricular ejection fraction less than 45 percent measured by multiple gated acquisition scan (MUGA) or echocardiogram (ECHO)
Hypertension not controlled by medical therapy (systolic blood pressure greater than 150 mmHg or diastolic blood pressure greater than 100 mmHg).
Uncontrolled intercurrent illness including, but not limited to, ongoing or active infection, symptomatic congestive heart failure, unstable angina pectoris, cardiac arrhythmia, or psychiatric illness/social situations that would limit compliance with study requirements.
Patient known to be human immunodeficiency virus (HIV) positive and requiring antiretroviral therapy.
Currently active diarrhea that may affect the ability of the patient to absorb ZD6474 or tolerate further diarrhea.
Patients on therapeutic anticoagulation
Patients with known bleeding disorders
Pregnant women are excluded from this study because ZD6474 is an anti-angiogenic agent with the potential for teratogenic or abortifacient effects. Because there is an unknown but potential risk for adverse events in nursing infants secondary to treatment of the mother with ZD6474, breastfeeding should be discontinued if the mother is treated with ZD6474.
Any known hypersensitivity to ZD6474 or other excipients of ZD6474.
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00566995
|United States, Maryland
|National Institutes of Health Clinical Center, 9000 Rockville Pike
|Bethesda, Maryland, United States, 20892
|Principal Investigator:
|W. Marston Linehan, M.D.
|National Cancer Institute (NCI)
Additional Information:
|Responsible Party:
|W. Marston Linehan, M.D., Principal Investigator, National Institutes of Health Clinical Center (CC)
|ClinicalTrials.gov Identifier:
|NCT00566995 History of Changes
|Other Study ID Numbers:
|First Posted:
|December 4, 2007 Key Record Dates
|Results First Posted:
|March 11, 2015
|Last Update Posted:
|April 7, 2015
|Last Verified:
|March 2015
Keywords provided by W. Marston Linehan, M.D., National Institutes of Health Clinical Center (CC):
Kidney Tumors
Clear Cell Renal Cancer
VEGFR Inhibitor
EGFR Inhibitor
Von Hippel Lindau
Kidney Tumor
Additional relevant MeSH terms:
Von Hippel-Lindau Disease
Kidney Diseases
Urologic Diseases
Nervous System Diseases
Vascular Diseases
Cardiovascular Diseases
Kidney Neoplasms
Carcinoma, Renal Cell
Urologic Neoplasms
Urogenital Neoplasms
Neoplasms by Site
Neoplasms, Glandular and Epithelial
Neoplasms by Histologic Type
Neurocutaneous Syndromes