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How Bark Works
1.Post details
Post details of your Carpet Cleaning requirement in moments, completely free.
2.Find professionals
We will find Carpet Cleaners in Moreton and do the legwork to contact them on your behalf.
3.Get quotes
Receive fast, free Carpet Cleaning quotes from the best Carpet Cleaners near Moreton.
Review proposals, compare Carpet Cleaning prices and choose the best local Carpet Cleaners for your job.
5.Write review
Submit a review to help others find recommended Moreton Carpet Cleaners
Carpet Cleaners in Moreton
Finding the right carpet cleaning company in Moreton, Essex can be a daunting process, thankfully using Bark to find the best carpet cleaning company in Moreton, Essex is fast, easy and free!
Whether you've spilt some wine on the carpet, you're coming to the end of your tenancy on it or a whole host of other reasons you might need it cleaned; we're sure to have you covered.
Raising a carpet cleaning request on Bark will enable us to reach out to carpet cleaners in Moreton, Essex to find the best cleaner for you.
Once we've found a selection of professional carpet cleaning companies that we think are right to help with your request we'll ask them to reach out to you directly. You can then discuss your carpet cleaning needs with them on the phone in detail.
Once you are happy with the carpet cleaning companies in Moreton, Essex, you have spoken with you can decide on one based on their quote and Bark reviews.
Bark's service for finding upholstery cleaning quotes in Moreton, Essex is completely free, and we put you in touch with the carpet cleaning company directly.
There are a large number of different types of carpet cleaning that you choose from we've listed some of the most popular uses below as a guide, so you know which is the best method to clean your upholstery.
- Steam Cleaning - This method uses hot water or steam to agitate the carpet, dissolving and freeing the dirt. This is one of the most common methods of carpet cleaning.
- Carpet Shampooing - This is a relatively outdated method of carpet cleaning, and you'll find that the majority of carpet cleaners in Moreton, Essex will not use this anymore as it leaves behind a residue.
- Encapsulation - Foam encapsulation uses synthetic detergents that once dry, will turn into to a dry powder. The loosened dirt will be encapsulated in the powder and then can be vacuumed from the carpet afterwards. This is a common and effective method that many carpet cleaning companies in Moreton, Essex will use.
- Bonnet Cleaning - This is a popular method for commercial carpet cleaners in Moreton, Essex and involves a large spinning fabric disc soaked in detergent. This 'scrubs' the carpet and pulls up any dirt. A common place to see this is hotels.
- Dry Carpet Cleaning - This involves a dry chemical that will absorb the dirt when scrubbed and the dissolves it. The residue can be hoovered after the carpet is clean.
Carpet Cleaners in Moreton ready to help
Excellent Plus Ltd
Excellent plus is a new family company with a year of expiration like employed. We offer quality, high responsible and fast work . We provide a 24-hour domestic and business professional service in London and surrounding areas. We give a completely care for your carpet and our customers - "You deserve to breathe in fresh air". We have a very competitive call-out charges in most cases refundable and no other hidden costs. Payment for any work is due on satisfactory completion of the work, so you can feel safe with us.
Trendy Cleaning And Services Ltd
We offer a variety of services, including office cleaning, warehouse cleaning in Greater London but our specialty and best-selling service is home cleaning. Our team consists of highly experienced and trustworthy professionals, who will make your place spotless and healthy for you and your family! *** Our main services are the | CARPET & UPHOLSTERY | PRESSURE WASHING | END OF TENANCY | OVEN | cleaning ***
Cheap Deep Cleaning Ltd
We welcome you as our new customer to our company.Our company provide cheap and quality cleaning.We offer commercial and domestic cleaning services .We will give you a complimentary price quote fot cleaning services that will fit your needs and your budget.
RGV Multiservices Ltd
At RGV , we are a professional company based in Uxbridge supplying multi-services to both private customers and businesses in and around London . From cleaning to property maintenance , removals or onsite-services , we strive to offer best services, in the most cost effective ways to both our existing clients as well as new ones . For more information , services and reviews from existing clients ,please visit our website : www.rgvmultiservices.com
Ivoryrose Cleaning Services Ltd
IvoryRose is a first class cleaning specialist in London and the South East. We have built a reputation for providing an exquisite service at a very competitive price. Our attention to detail is exemplary and we consistently offer a quality finish that is sure to satisfy your needs. We offer a wide range of services that are flexible enough to cater to the specific needs of your home or business. Whether you need commercial cleaning, home cleaning, pre or end of tenancy cleaning, window cleaning, carpet cleaning, office cleaning or shop cleaning we're sure to have the right package to suit you. We cover a wide range of areas in London and all over the south east. Where ever your home or offices may be, our team of dedicated cleaners can get to you promptly. With our hub in the heart of London we're very near to north, east, south, west and central London. We also specialize in areas such as Rainham, Barking, Seven Kings, Hornchurch, Grays, Purfleet, Redbridge, Romford, West Thurrock, Stanford LeHope, Chafford Hundred and all surrounding areas. We're a company of the highest standards who always insists on excellence. All our staff are DBS checked and undertake thorough health and safety training which underpin all the work we carry out.
MTL Property Cleaning services
Here at MTL Cleaning Services we offer a wide range of services from window cleaning,pressure washing,gutter clearence and repair plus end of tenancy cleaning. For our building services ie : Builders cleans. Window cleaning. All staff have public liability insurance and IPAF and CSCS cards. We also have DBS police clearance for sensitive areas such as Schools,Academy's and Hospitals . You can visit us at yell.com or Facebook. Just enter. MTL Property Cleaning Services
Professional Cleaning Services for Shining Properties Choose the cleaning service you need and get any building professionally cleaned. All cleans are carried out by experienced cleaners, with special equipment and chemicals. ⇒ End of tenancy cleaning Top to bottom deep cleaning of rented buildings. Special discounts for landlords and agencies. ⇒ Carpet cleaning Dirt and stains removal from carpets with professional Prochem equipment and chemicals. All carpet cleaning services are available at a discount when booked together with another service. ⇒ Domestic cleaning Regular home cleaning, catering to individual needs. Weekly and fortnightly rates available. ⇒ Office cleaning Daily, weekly and one-off cleaning of offices and commercial spaces. The entire London areas are covered, M25 included.
Renaissance specialist cleaning
A reputable & proffesional cleaning company established since 1990 in pursuit of exellence with high customer satisfaction high standards of cleanliness and reliable and honest service bespoke services to customer requirements with a wealth of experience and knowledge and know how in the domestic market our technicians have been fully trained to every aspect of the job.we have a experienced team available in all these above areas, we specialize in one off cleans,end of tenancy cleans, spring cleans,deep cleans,oven cleaning dishwashers cleaned and carpet and upholstery cleaning mattress cleaning, rug cleaning curtain steam cleaning, ,stain removals, leather cleaning, mould removal, fumigation,sanitizing,trauma cleaning one of the very few cleaning service provider companies in the uk that cater for every aspect of the domestic cleaning market your one stop cleaning experts
Blues brothers bests of...
Cleaning is the one chore that most people are either too tired or simply reluctant to do. It's easy to understand that after a long day or week at work, you'd rather spend time with your family, enjoy a hobby, relax in front of the TV or catch up with friends. So why not enjoy your downtime and leave the cleaning to professionals? We're a small family-run cleaning company with great potential and an enthusiasm to take on cleaning challenges. Not only do we know what we're doing, we can do it in half the time it would take you to complete the task. Every member of our team is trained to professional standards and we take great pride in sprucing up spaces until they are spotless. Whether you only want your windows and carpet cleaned or would rather have a deep clean after a party, we'll do what needs to be done to have it sparkling and pristine. We do not mind taking care of any extras to keep you happy – we love it when our loyal clients recommend us with glowing reviews about our attention to detail and high standards of hygiene. There's nothing too small or too large that we can't handle. We are flexible and do our best to accommodate same-day bookings. Please contact us to discuss your specific requirements and we'll be happy to be of service. SINCE NOW WE ADDING TO BIDVINE: RUBBISH REMOVALS, ALL TYPES OF REMOVALS AND DELIVERYS,PROPERTY MAINTENANCE + HANDYMAN SERVICE, FELL MORE THAN WELCOME TO CONTACT IS FOR FREE QUOTE - Peter;)
Zones Cleaning Services
Zones Cleaning provides an excellent service on every occasion. Over 20 Years experience providing outstanding service Cleaning tasks will be carried out to an exceptionally high standard We Guarantee all work will pass the inspection. Our staff are prepared to return to rectify any faults, Our staff are professional and highly trained to carry out all cleaning tasks that our clients require. We work very hard to make our cleaning as ABC(Always Brilliant firstname.lastname@example.com Great attention is paid to Customer Service, whether Corporate or Individual Clients Our Motto: We Don't Cut Corners.. We Clean Them Sample End of Tenancy Cleaning: Walls, Sockets & Light Switches - Dust and clean to remove scuffs, finger marks and cobwebs Covings & Ceilings - Remove cobwebs. Woodwork, Stairs, Balustrades and handrails - Vacuum, dust and clean to remove scuffs and finger marks. Fire Places(Not Chimneys) - Clean sweep and polish. Vinyl, Wood and Tiled Floors - Wash, polish, treat and clean. Paintwork - Clean and dust: skirting boards, architraves, picture rails, dado rails, door frames, window frames and sills. Furniture - Move clean and polish, including the inside of drawers and cabinets, clean behind/under and return to original position. Soft Furnishings - Vacuum all covers, including beneath cushions. For leather upholstery wipe with a clean damp cloth. Curtains, Pelmets, Blinds & Net Curtains - Vacuum Ceiling and wall Lights - Clean, remove cobwebs( including shades) Windows - Clean inside and out (where access permits) KITCHEN Units - Clean inside and out, including drawers, cupboards including the top and bottom to remove dust, dirt and grease. Work Surfaces - Clean and polish Sink, Unit, Taps and Faucets - Remove all lime scale and water marks, clean and buff Cooker/Stove - Clean and degrease including any grill pan and oven racks Fridge & Freezer - Defrost, Clean inside and out( including top) and deodorise) Switch off at mains and leave the door(s) ajar Dishwasher/washing machine - Clean inside and out including: soap and fabric softener, drawer, filters and rubber seal. Tumble Dryer - Clean inside and out ensuring filters and hoses are cleaned thoroughly and condenser tank emptied Microwave - Clean inside and out including turntable and grill (where applicable) Extractor Fans and Cooker Hoods - Clean and degrease BATHROOMS Bath, WC, Bidet & Shower Cubicles - Remove all lime scale and water marks, clean and buff Taps, faucets and Fittings - Remove all lime scale and water marks, clean and buff. Visible Pipes- Clean, dust and polish where accessible Shower Screen and Tiles - remove all lime scale, mould and water marks and then polish Mirrors & Glass - Clean and Polish Extractor Fans - Vacuum and wipe clean REFUSE All refuse and unwanted items should be removed from the Premises OUTSIDE SPACE INCLUDING TERRACE, BALCONY, PORCH & CELLAR Sweep, tidy and remove any refuse Services offered are: Daily Office Cleaning End of Tenancy Cleaning Carpet and Upholstery Cleaning One Offs Deep Cleans for Residential and Commercial Properties We cover London areas and suberbs Call today: 020 8699 0033 or E-mail; email@example.com For a Free Quotation We have gained excellentn feedback nand testimonies over 20 Years. Our Motto is: "We Don't Cut Corners... We Clean Them"
5 Star Sparkle
We offer Professional Carpet and Upholstery cleaning company. We are a small team of qualified Professionals and specialise in End Of Tenancy Carpet Cleaning both for Domestic and Commercial premises.over the past 5 years we have serviced many hotel's from premier inn, B&B's and commercial properties, schools and offices. We use Professionial equipment, we use a Truck Mounted ETM 800PSI triple vacs, with an inbuil t 3k heater Carpet cleaning machine and professional Prochem products for stain removal, high traffic etc.
EcoClean & Property Services Ltd
EcoClean are a professional office cleaning company covering Essex and London. We also specialise in carpet, upholstery and hard floor cleaning for both commercial and residential premises.
CleanPro Services Ltd
CleanPro Services specialize in a compact range of cleaning services to ensure a quality service is provided to the customer by qualified members of the team. Our services include : End Of Tenancy Cleaning, Office Cleaning, Carpet Cleaning, Window Cleaning, Oven Cleaning, Serviced Property Cleaning, After Builder Cleaning, Pressure Washing. All staff are dbs checked and we are fully insured for your peace of mind. Dont hesiate to get in touch for a quote/enquiry
Maintain Cleaning Services Ltd
We are a family run, local cleaning company that has over 28 years experience in the industry! Our aim is to leave each and everyone of our clients feeling like they have spent their money extremely well. Offering a wide range of services to the following areas - Bedfordshire, Hertfordshire, Cambridgeshire, North & West London. At Maintain we understand that day to day life can be very busy and stressful and we always try to work to our clients needs. Get in touch today for more information about us, advice or to book in your free written quote! Sean and the family look forward to working with you. Check out our latest promotions and offers on Facebook/Twitter/Instagram or take at look at our website for more details www.maintaincleaningservices.co.uk
Our goal is to provide the highest standard of cleaning at a reasonable and competitive price, and to meet your highest demands. CQD Cleaning Services has special teams of cleaning technicians operating all over High Wycombe, Marlow, Reading, Maidenhead, Milton Keynes Chesham,Slough,Oxford & surrounding areas still growing,using industrial and commercial cleaning products, detergents and dust which is all too often left over daily. Property sizes and conditions can vary widely when it comes to after cleaning. Prices for our cleaning service, including materials, equipment, and a team of cleaners are subject to no obligation site inspection.
Cleanbright Solutions UK has over 30 years experience providing high quality cleaning services to the Barnet, North London and Hertfordshire area. Being a family run business we pride ourselves on delivering a reliable, professional and affordable cleaning service to both our local commercial and domestic customers. Our wide range of cleaning services include Carpet, Curtain and Upholstery Cleaning, Tile and Grout Cleaning and Patio and Driveway Pressure Washing. If you need cleaning for your home or office look no further than Cleanbright Solutions UK. Using the latest American Truck-mounted Cleaning machine we can promise our customers the deepest and driest clean possible leaving your carpets as fresh as the day they were laid. Please visit our website for full details on how we can help you.. www.cleanbright.co.uk or call us on 020 8449 0209
Eco Clean Homes
We are a family owed and operated business that takes pride in doing a fantastic job cleaning for our customers at a very competitive rate and without harming Mother Earth in the process. We provide one off's and regular domestic cleaning, Comercial cleaning, window cleaning and carpet cleaning.
Fast Cleaners Croydon
Fast Cleaners Croydon offers services ranging from carpet cleaning, commercial cleaning, rug cleaning and many more! Our cleaners are here to make your space sparkling clean! Call us today on 020 3322 1893 for a free quote.
Revive and Sanitise
Welcome to Revive & Sanitise and our page. Please visit us regularly to keep up to date with our latest special offers. Revive & Sanitise are a family-run domestic and commercial Carpet and Upholstery cleaning service. We are based in central Bedford - and cover up to 25 mile radius, including Bedfordshire, parts of Buckinghamshire (Milton Keynes, Bletchley), Northamptonshire (Rushden, Wellingborough) and parts of Cambridgeshire (St. Neots, Sandy, Biggleswade) – and we may consider further afield if required. We offer a wide range of excellent services, starting with our standard deep-steam cleaning plus Sanitising, Deoderising and Stainguard protection. Below are just some examples of what our clients have hired us to clean. Full house end of tenancy cleaning Carpets and Stairs Regular and Oriental Rugs Settees, sofas, chairs and footstools Floor coverings Leather furniture Antiquated furniture office space carpet and upholstery cleaning Cars and Motor Home interiors And even coach and bus interior cleaning!
Clean & Garden Ltd
Clean & Garden Ltd is professional and passionate cleaning and Garden maintenance service provider. We take delight in leaving our customers with the best smile possible. We treat our customers with respect, we don't just treat them like number but as real people with unique needs. Why should you choose Clean & Garden? because all our staff our highly trained, fully vetted, insured and we offer guarantee for all our services.
Cleaning Perfect
We have a long and proud history delivering Blitz Cleaning services since 2011, helping people to live comfortably in their own homes. We take pride in helping people who need it most, undertaking Blitz Cleans for vulnerable adults in the following Local Authorities, Royal Borough of Greenwich, Lambeth, Bromley, Croydon, Lewisham, Southwark, Bexley, Kingston, Hounslow, Hammersmith and Fulham, Westminister, Islington, Tower Hamlets, Newham, Haringey, Barnet, Hackney, Kent, Surrey, Essex, Middlesex, Surrey and London. We provide council contract cleaning London and Blitz or deep cleaning services on heavily cluttered properties that require de-cluttering and or heavy duty cleaning. This can include jet and steam cleaning of hard and soft furnishings, as well as removal of unwanted items. London Blitz Clean has been a prominent player in residential clutter clearance for several Local Authorities, Housing Associations, Residential Homes, Nursing homes, Women/Men homeless shelters, drug rehabilitation units and private landlords in London. Our friendly, expert cleaners pride themselves on providing exceptional standards of cleanliness, whilst showing sensitivity to the home owner, providing professional and bespoke cleaning services in London. Our team of specialists assure no job is too big or too small and use approved and tested procedure and equipment to achieve excellent results with every clean.
Lee Bassett Carpet & Upholstery Cleaning
Professional cleaning of all types of wet-cleanable carpets and upholstery. Reliable & conscientious service at sensible prices. Fully insured. Over 25 years experience.
Neighbourhood Carpet CleanersCertificate of Excellence 2015
Neighbourhood Carpet Cleaners is a London based professional cleaning company, specialising in Carpet Cleaning and End of Tenancy Cleaning Services. The company was founded in 2012 and also provides Jet Washing and Gardening services. Due to our diverse range of cleaning services, we are able to provide bespoke, tailor made property restoration services for Landlords, Estate Agents, Lettings Agents, SME's and Corporate Organisations.
Dan Hooper
We'll match or beat the price of any cleaning service from competitors. Domestic And Commercial Cleaning Domestic Cleaning Commercial Cleaning Regular Cleaning Builders Cleans Spring Cleaning Sparkle Cleans Upholstery Cleaning Office Cleaning Carpet Cleaning Factory Cleaning Window Cleaning Schools Cleaning Oven Cleaning Contract Cleaning Laundry/Ironing Services Holiday Let Cleaning End of Lease Cleans Elderly House Cleaning One-Off Cleans Restaurant Cleaning End of Tenancy Kitchen Cleaning Moving out Clean Upholstery Cleaning What Do We Do We offer daily, weekly, monthly cleaning services to all... Out of hours cleaning services available - Fully insured - All Staff CRB checked All staff follow our strict privacy and confidentiality policy. Excellent testimonials on request - Key Holders and Burglar Alarm awareness Reliable, trustworthy and efficient staff - CIS Registered Domestic and Commercial Our dedicated teams of staff clean a substantial amount of both domestic and commercial premises on a regular basis. We have a very high standard and take pride in all our work. We are extremely security conscious and respect the privacy of our customers and therefore make sure our staff are vetted and reference checked before they are able to start work. Builders Cleans Our Builders Cleans take us across the UK working alongside national and local building and construction companies. We carry out our builder's cleans to new and refurbished premises working 24/7 if required to enable us to execute the work with the set timescale. We are very well accustomed to the 'last minute' call and have the flexibility and commitment to accommodate the short notice and changes to schedules. We are CIS registered, fully insured and comply with Health and Safety Regulation
Professional carpet and upholstery cleaning, mattress cleaning, rug cleaning. Dirt and odour removal. Pet stains removal. We are a small company, striving to deliver excellent service. If you are looking for professional carpet cleaning services in London to take care of your expensive floor coverings you've reached the right place. We will use state-of-the-art equipment and modern techniques to clean your carpets. Not only we eliminate dirt, stains, and bacteria, we also help you prolong the life of your carpets. Our specialists carpet cleaners are certified to use the equipment, minimising the risk of damage and accidents. We care for your floor coverings in a way you'd like us to, and select cleaning chemicals carefully after analysing the quality and material of your carpet. We use mild chemicals that protect the carpet fibres, while ensuring 100% elimination of any dirt. We make no compromises – we make sure your carpet looks like new. Every time!
Nw4 carpet cleaning
We provide professional carpet cleaning services in North London and all London. All of our carpet cleaning involves individual treatment and removal of stains using professional products and powerful steam cleaning extraction machines, ensuring your carpets are left as clean and dry as possible. Thoroughly cleaned carpets are anti-bacterially treated then deodorised. All cleaning agents used are bio-degradable and environmentally friendly. Our carpet cleaners are trained professionals and can advise you on the best cleaning system for your carpet.
Easy Cleaning London
Easy Cleaning London
Sharafi & Co
We are a wholesale supplier of Antique and Bespoke Persian and Oriental rugs to leading dealers and collectors. We are open by appointment to the public. Our online retail clients come to us because they want unusual oriental rugs and carpets quality goods at competitive prices, purchased from a reliable source. We have one of the largest selections of Persian Tribal Kilims. We are highly respected in the antique oriental rug industry for oriental carpet cleaning and rug restoration.
J Clean
Splendclean Ltd
Shine and Sparkle Cleaning
We deliver friendly and efficient commercial and domestic cleaning services in Greater London and Essex. Our highly trained staff by using the latest equipment is ready to provide the best service tailored to your needs. Customer satisfaction is guaranteed at a competitive price. We do not leave till you are happy with everything. We are a small business where everyone takes full responsibility and ownership. It is our company and therefore we provide high-quality service at all the time. We have years of experience and know what needs to be done for your 100% satisfaction. We also specialize in Deep Carpet Cleaning with our professional hot extraction machinery (shampoo and hot extraction method) We can give you 40% discount on that if it is combined with End Of Tenancy cleaning. A little bit more about our services: - Weekly domestic cleaner: Same cleaner every week, tailored cleaning checklist, you can request anything from ironing to washing up - End of Tenancy cleaning: Proper deep cleaning of your home. We take away the stress that moving comes with and guarantee that you get your deposit back. Oven, fridge and terrace cleaning are available too. - One-off cleaning: If you need us for a deep cleaning of your bathroom or kitchen, we can give you a customized quote. We will make sure everything is spotless.
J&A Flawless Clean
We provide domestics and commercial cleaning along with handy men and removal services with excellence.
We specialise in personalised cleaning services plan for our clients as well as general cleaning services. Residential & Commercial We serve clients of all nature. Whether you require assistance around the house or want regular cleaning of the office. We are here to take care of it all. Regular & Seasonal Cleaning For the occasional or seasonal clean out or a regularly scheduled service. We can take the burden of cleaning off your shoulders leaving you to get on with the more important stuff. Specialist & Eco Friendly We use specialist equipment and Eco-friendly products to assure you excellent quality of work and a great healthy environment.
Easy Housekeeping is a company that embraced technology to simplify the relation of customers requiring on-demand cleaning services. We employ state of art technologies in our professional scheduling service that makes great experiences for customers and amazing housekeepers like you to transact in a legal, safe and secured environment.
Roffey Cleaning
Roffey Cleaning provide professional carpet and upholstery cleaning using hot water extraction and the latest dry cleaning techniques with the envirodri system. We are fully insured members of the National Carpet Cleaning Association and provide a friendly local service across Southend and Essex.
Aqua Cleaners LTD
Aqua Cleaners Ltd offers professional carpet, upholstery and hard floor cleaning. We are Prochem trained and certified, therefore we operate to a very high standard producing excellent results. Aqua Cleaners Ltd also has full public liability insurance to give our customers that added peace of mind.
Carpet Cleaners on Bark
We have 4682 Carpet Cleaners actively using Bark.com.
We'll reach out to them as well as others, based on your requirements.
Within hours, sometimes minutes, they'll contact you on Bark.
Professionals value their reputation on Bark and strive to do a great job for customers they find on our platform.


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Truncating mutations in the giant sarcomeric protein Titin result in dilated cardiomyopathy and skeletal myopathy. The most severely affected dilated cardiomyopathy patients harbor Titin truncations in the C-terminal two-thirds of the protein, suggesting that mutation position might influence disease mechanism. Using CRISPR/Cas9 technology, we generated six zebrafish lines with Titin truncations in the N-terminal and C-terminal regions. Although all exons were constitutive, C-terminal mutations caused severe myopathy whereas N-terminal mutations demonstrated mild phenotypes. Surprisingly, neither mutation type acted as a dominant negative. Instead, we found a conserved internal promoter at the precise position where divergence in disease severity occurs, with the resulting protein product partially rescuing N-terminal truncations. In addition to its clinical implications, our work may shed light on a long-standing mystery regarding the architecture of the sarcomere.https://doi.org/10.7554/eLife.09406.001
The heart is able to beat partly because of a large protein called Titin that helps to give heart muscle its elasticity. Mutations that shorten the gene that encodes Titin can cause part of the heart to become enlarged and weakened, a condition called dilated cardiomyopathy. Some people with shortened copies of this protein have a mild form of cardiomyopathy and are able to lead relatively normal lives. Others develop more severe symptoms that prevent the heart from pumping blood effectively and may even cause the individual to need a heart transplant.
Genetic studies have revealed that mutations that shorten the Titin protein by disrupting the portion of the gene corresponding to the latter two-thirds of the protein (which encodes the so-called "C-terminal" end of the protein) cause more severe symptoms than mutations that occur near the start of the gene. But it is not clear why the location of the mutation matters.
To investigate this problem, Zou et al. used a gene-editing tool called CRISPR to create genetically engineered zebrafish. These fish had mutations at one of six different points in the gene that encodes the zebrafish version of Titin. Just as with humans, mutations near the C-terminal end of the gene caused more severe muscle problems in the fish.
Specifically, Zou et al. found that the worst disease was associated with mutations that occurred at or after a "promoter" region within the gene and near this C-terminal end. Normally, the promoter produces an independent smaller form of the Titin protein, which helps to reduce the severity of muscle problems in zebrafish that have mutations near the start of the gene. However, mutations near the C-terminal end of the gene also damage this smaller form, preventing this failsafe from working, and so lead to more severe symptoms. Zou et al. also found this promoter to be active in both mouse and human hearts.
Future work will focus on learning how this smaller form of Titin works to help muscle develop and withstand stress and determine whether increasing its production can overcome the more severe forms of disease.https://doi.org/10.7554/eLife.09406.002
The use of genetics in clinical medicine depends on knowledge that an identified mutation confers risk of disease. Recent guidance issued by the American College of Medical Genetics emphasizes that the strongest form of evidence supporting causality of a mutation is whether it results in a truncation of the protein (nonsense, frameshift or canonical splice-site mutations), specifically for genes where loss-of-function mutations are known to cause disease ( Richards et al., 2015 ). Truncating mutations within alternatively spliced exons and at the extreme C-terminus of the protein must be interpreted with caution, as they may have little to no impact on protein function. However, the guidelines do not address whether truncating mutations at different positions along the length of the protein might differ in phenotype severity or mechanism of action, a finding that could complicate interpretation of truncation mutations for a broad range of inherited diseases.
The web framework for perfectionists with deadlines.
Everything you need to know about Django.
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Django has a lot of documentation. A high-level overview of how it's organized will help you know where to look for certain things:
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Django provides an abstraction layer (the "models") for structuring and manipulating the data of your Web application. Learn more about it below:
Django has the concept of "views" to encapsulate the logic responsible for processing a user's request and for returning the response. Find all you need to know about views via the links below:
The template layer provides a designer-friendly syntax for rendering the information to be presented to the user. Learn how this syntax can be used by designers and how it can be extended by programmers:
Django provides a rich framework to facilitate the creation of forms and the manipulation of form data.
Learn about the various components and tools to help you in the development and testing of Django applications:
Find all you need to know about the automated admin interface, one of Django's most popular features:
Security is a topic of paramount importance in the development of Web applications and Django provides multiple protection tools and mechanisms:
Django offers a robust internationalization and localization framework to assist you in the development of applications for multiple languages and world regions:
There are a variety of techniques and tools that can help get your code running more efficiently - faster, and using fewer system resources.
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Django offers multiple tools commonly needed in the development of Web applications:
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subset: commoncrawl


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Ok, I considered putting this in web development, because it is a good example of a VERY bad site.
Anyway, I am looking for some different translation software, because my company has been haveing problems communicating with a couple of clients over seas. I decided to checkout http://systransoft.com/ to see what they had. On their main page, they have 8 little flags in the top right corner. Being curious, I decided to check them out an see what they are all about. Well, here is a screen shot of the results.....Either check it out, or try for yourself.


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Just came back from a break and have been trying to get into VW, mainly doing stuff with friends so I get to come whatever, people have been telling me that spiral is the best non-empy WS(which I'm working on... 17/50 buds and 19/50 fangs) for VW, what is the concensus and/or math pertaining to this. Any help would be appreciated, thanks guys xoxoxoxoxo :3
Just wanted to note that I scrolled through and didn't see a topic like this so I'm sorry if it has already been asked.
Edited, Nov 27th 2012 2:39am by itege


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Annual grades fall sharply for Florida schools
A-rated schools fall 39 percent
Annual grades fall sharply for Florida schools
A-rated schools fall 39 percent
TALLAHASSEE, Fla. —
The number of top-rated schools in Florida has fallen sharply.
The Department of Education on Friday released new A to F grades for many of the state's public schools.
The grades showed that the number of A-rated schools fell nearly 39 percent this year, while the number of F-rated schools more than doubled.
The number of F-rated schools could have been much higher. Earlier this month, the State Board of Education voted by a 4-3 margin to tweak the formula that allowed as many as 150 schools to avoid getting an F grade.
The decision to change the grading standards was done over the protest of some officials who said the move would confuse parents and mask the true performance of many schools.


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2012 Mazda Mazda5 Values
Select a 2012 Mazda Mazda5 trim level
Mazda Resources:
2012 model year changes
The Mazda5 is all new for 2012, with a resculpted, dynamic look on the outside, better interior detailing and a slightly larger, more powerful engine--without affecting fuel economy. And with the stylish new look inside and out, around the idea of "seductive smartness," it doesn't give up any interior space or functionality.
Competitive comparison
Seating for six; space-efficient layout; versatility; steering and handling; fuel-efficiency; new, more stylish look
Special features for 2012
The Mazda5's sliding side doors might lead some to dismiss it as a minivan, but they shouldn't; there's nothing else on the market quite like this unique vehicle, which combines some of the attributes of a minivan (but smaller) and a crossover utility vehicle (but lower). The Mazda5 has excellent passenger design: It takes up about the same parking footprint as a compact sedan, but it has comfortable seating for six. Mazda says that even with all six seats up in place, there's enough cargo space for a standard baby stroller. Also, the sliding doors are easy to operate and are easier to manage when in tight parking spaces. Furthermore, this model is already known for its entertaining driving character, and with a little more power and steering and suspension tuned even more for handling, the Mazda5 is one family choice for those who like the twisties.
Receiving its first massive makeover since the Mazda5's introduction in 2006, Sport, Touring and Grand Touring trim levels showcase the 6-passenger 2012 Mazda5. While the Mazda5 Sport is the base model, a sizable standard convenience listing features air conditioning and 6-speaker MP3-capable stereo system. With few options available on trim levels, upgraded features will be presented standard in the 2012 Mazda5 Touring or Grand Touring. Bluetooth becomes standard on the Touring model while leather seating and HID headlamps are only appearing on the Mazda5 Grand Touring. Replacing the 2.3 liter engine with a larger, more potent 2.5 liter inline-4 worth 167 horsepower, front-wheel drive power is routed through either a brand new 6-speed manual or 5-speed automatic gearbox. The engine paired with either transmission produces fuel economy of 21 miles city or 28 miles highway per single gallon of gasoline. Rightfully for a family-based vehicle, all 2012 Mazda5 are loaded with standard safety features including stability control with traction control as well as front, side and curtain air bags.


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Do you know you can win a DISCOUNT COUPON by submitting your review for an apartment rental or hotel in Sofia. Simply send us your valuable comment on a Sofia hotel or apartment you have visited and we will send you a discount coupon for one of our travel services. Your review will provide useful information to our visitors looking for an accommodation in Sofia, Bulgaria.
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Updated: 19 March 2007 to resolve some errors
In my last post ("How small can you go?" 22 Jan 2007) I presented a custom control that allowed you to determine if the control was below a specific size, and to alter its visual appearance based upon this. There are many cases however where altering appearance based upon size is important (for example, to make the thumb grips on scrollbars disappear when they become too small), and I felt a more generic method of performing this calculation was required.
Ideally this method would not require a special base class as described in my previous post. It should also be as general as possible, allowing bindings to any available dependency properties.
So let us consider how we currently implement triggers,
<Trigger Property="IsMouseOver" Value="True">
<Trigger Property="Width" Value="150">
The first of these examples makes perfect sense. The IsMouseOver property is either true or false. We apply the default style when it is false, and apply any changes specified within the Trigger when it is true. However, the Width property does not have a small number of distinct values. Whilst the above trigger will apply if the width equals 150, it will not if it is 149,148,147,etc. or 151,152,153,etc. If only we had a less-than trigger...
Now let me introduce the IValueConverter interface. This according to the MSDN documentation "Provides a way to apply custom logic to a binding." Basically it allows you to include some logic that alters the value of the property before the trigger performs its comparison.
For example,
<DataTrigger Value="True" Binding="{Binding RelativeSource={RelativeSource Self}, Path=ActualWidth, Converter={StaticResource addTenConverter}, ConverterParameter=150}">
Here we specify a custom converter, whose logic simply adds ten to a value. Therefore if the Width of our element is 140, the binding will first call our converter, which will of course return 150. Since this matches the Value attribute, the trigger will be applied. The converter just sits between the Property and the comparison to Value and provides some conversion.
So how does this help us? Well, there is one more attribute we need to introduce. The ConverterParameter attribute allows us to supply an additional parameter to our converter when it does its stuff. Now we can envisage,
<... .Resources>
<cvt:LessThanConverter x:Key="LessThanConverter"/>
</... .Resources>
<DataTrigger Value="True" Binding="{Binding RelativeSource={RelativeSource Self}, Path=ActualWidth, Converter={StaticResource lessThanConverter}, ConverterParameter=200}">
Note that we create an instance of the converter as a static resource. The actual code behind the converter is relatively straightforward. All we do is take the supplied value, compare it to the supplied parameter, and return true if the value is less otherwise return false. In fact this is slightly more complex. Whilst a ValueConversionAttribute may be applied to the converter class specifying the type for the parameter, when written in XAML as shown above this is ignored and a string is supplied anyway. Therefore the resulting code is,
using System;
using System.Windows.Data;
using System.Globalization;
[ValueConversion(typeof(double), typeof(bool), ParameterType = typeof(double))]
public class LessThanConverter : IValueConverter
public object Convert(object value, Type targetType, object parameter, CultureInfo culture)
double doubleValue = (double)value;
double doubleParameter;
if (parameter is double)
doubleParameter = (double)parameter;
else if (parameter is string)
if (!Double.TryParse((string)parameter, out doubleParameter))
throw new FormatException("The parameter for this LessThanConverter could not be converted to a System.Double");
throw new ArgumentException("The parameter for this LessThanConverer is of an unsupported type", "parameter");
Console.WriteLine("{0} < {1}", doubleValue, doubleParameter);
return doubleValue < doubleParameter;
public object ConvertBack(object value, Type targetType, object parameter, CultureInfo culture)
return new NotSupportedException();
So now we can trigger when any dependency property that is defined as a double is less than a specified value. The original problem from part 1 however involved changing the appearance of a window when either of the Width or Height properties were below a certain threshold. We can specify two separate triggers, but this requires duplication of all the setters within them. What we really need is some way to apply a 'logical OR' operation to two or more triggers. Next time... The IMultiValueConverter interface.


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MMQB: Washington vs. Utah – Week 5 Recap
The Washington Huskies marched into Salt Lake City for the first time ever, looking to go 2-0 in Pac-12 play this season. And they did just that, with a sound 31-14 defeat of the Utes in their first home Pac-12 game…ever. This puts the Huskies at 4-1 overall and 2-0 in conference play, tied with Stanford and Arizona State as the only undefeated teams in Pac-12 play so far.
QB Keith Price is proving week by week that he's the real deal. He continued to show that again this week against Utah. He was a solid 22/30 for 226 yards and 3 touchdowns, with 1 unfortunate interception.
That gives Price 17 on the year, putting him in the #2 spot in the nation for passing touchdowns behind Baylor's Robert Griffin III, who has 18.
RB Chris Polk was half man, half amazing as he showed that last week's 60 yard performance was a fluke. This week he rolled to a whopping 189 yards rushing on 29 carries over a nationally ranked Utah defense that just could not seem to slow him down.
The Husky wide receivers didn't do too badly themselves, either.
Jermaine Kearse led the team with 7 catches for 70 yards and his team-leading 5th touchdown of the season. It was a big statement game for the senior, looking to get his licks in before he inevitably enters next year's NFL Draft. Devin Aguilar had 2 catches for 40 yards and a touchdown while true freshman Kasen Williams had 2 grabs for 30 yards and the third passing touchdown of Price's day.
On defense, the Huskies proved they can continue to make the big stops when necessary. Their biggest feat this week was only allowing an astounding 17 yards rushing on 23 carries for Utah. That is a 0.7 yards per carry average.
And continuing their growing trend this season, the Husky defense only allowed 7 points in the second half, in garbage time with Utah scoring with 7 seconds left in the game.
CB Desmond Trufant and LB Cort Dennison led the team with 4 tackles a piece with Trufant making 2 assists and Dennison coming up with 6 assists. Dennison was in on almost every play whether he was credited or not.
The Husky defense allowed over 300 yards again this game, but they made up for it in turnovers. They caused 4 fumbles, recovering 3 of them. CB Greg Ducre picked off one pass while S Sean Parker stole another. It was an impressive game all around.
The pressure they put in the Utah quarterbacks was tremendous and ended up being a game changer for them.
Yes, I said quarterBACKS. Starting QB Jordan Wynn was knocked out of the game by the third quarter, being replaced by QB Jon Hayes and the Huskies just kept plugging after that, taking advantage of almost all miscues thrown their way.
Each week, the Huskies seem to improve one aspect of their game while holding pat on the rest. If they continue at this rate, the Huskies are going to put up a serious fight for the Pac-12, and that's no joke.
They are already ranked #28 in the nation and climbing.
This week, Washington is on their Bye Week and will return to play in week 7, facing another team new to the Pac-12, Colorado, at Husky Stadium.
How bout them Dawgs?!


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To fix one problem, you have to potenually open yourself to another.The Apache Software Foundation recently released a software update that fixed a number of problems but also introduced a dangerous new security threat.
There have been a number of recent Apache Web Server vulnerabilities that require the attention of administrators, security professionals, and Webmasters. The threats pose various levels of danger and some can be exploited remotely
The most recent vulnerability is a remotely exploitable threat that can allow an attacker to compromise access controls. This is being referred to as the �Satisfy� directory threat. You can see the original advisory here (scroll down to the description). The threat from this vulnerability is that some password-protected folders won�t be protected if you update to Apache version 2.0.51.
A locally exploitable buffer overrun vulnerability in the configuration file variable .htaccess (Bugtraq ID 11182, CAN-2004-0747) affects a large number of Apache 2.x versions and is found in most Linux versions, including Mandrake, SuSE, Red Hat, and others. This threat has caused a number of users to update to version 2.0.51, making a large number of systems vulnerable to the remotely exploitable Satisfy vulnerability described above.


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For the best experience on the Abcam website please upgrade to a modern browser such as Google Chrome
Synthetic peptide:
C-SNPSYRTSTQEVK, corresponding to internal sequence amino acids 1765-1777 of Human LRP4 (NP_002325.2).
Our Abpromise guarantee covers the use of ab85697 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|Use a concentration of 0.1 - 0.3 µg/ml. Detects a band of approximately 200 kDa (predicted molecular weight: 216 kDa).
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"


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Angelo's Steakhouse Italian reflects the local culture of Murphys: A meat-oriented menu honors the area's ranching heritage, the rustic decor gives the feel of a trattoria in the Old Country, but the biggest cut sold here (40 ounces, usually for two to four people), is called "The Flintstone," after Fred of cartoon fame.
Angelo's Steakhouse Italian reflects the local culture of Murphys: A meat-oriented menu honors the area's ranching heritage, the rustic decor gives the feel of a trattoria in the Old Country, but the biggest cut sold here (40 ounces, usually for two to four people), is called "The Flintstone," after Fred of cartoon fame.
Yes, you are still in California, as the many local wines available on the menu demonstrate.
Plan ahead if you want to come here. On a weekend, you risk being turned away if you don't have a reservation. On a weekday, you might have the place to yourself if you come in the afternoon as we did on a recent Friday.
Service was courteous and prompt. We were invited to select our preferred spot and chose a table under a window. Our first discovery was the calamari appetizer ($9), which was the best either of us had ever had.
Rather than coarsely chopping the calamari as is typical, these were formed into a shape somewhat like a small breaded fish stick. The spicy aioli dipping sauce had a fiery but pleasing kick.
Watch for specials at Angelo's and be aware that they are cooked in the traditional ways. Many customers, for example, rave about the osso bucco, a roasted veal shank.
The night we were there, the special was a rack of lamb ($24).
The lamb was delicious, tender and very rare. That rare finish was excellent for me but wouldn't please everyone. The lamb came in a reduction sauce, a way to offer the intense flavor of well-cooked meat combined with the tenderness of the rare lamb.
The carrots and broccoli beside the lamb were cooked al dente. A sprig of fresh rosemary was in the mashed potatoes.
The other member of our party opted for the wild salmon filet topped with lemon preserve ($20). It was served with fingerling potatoes and baby carrots.
The salmon, too, was cooked to perfection, moist and tender. The portions were moderate, well within what most hungry adults can eat.
That's not to say that Angelo's couldn't take care of someone fresh off a month-long wilderness trek. The menu also includes a 12-ounce ribeye ($24), a 16-ounce T-bone ($25) and of course the famous 40-ounce Flintstone ($52). The Flintstone comes covered with crispy fried onions and two servings of pasta Bolognese.
Our server said that only once in his two years at Angelo's had he seen an individual finish the Flintstone without help.
Those desiring a dinner without red meat could choose any of a number of dishes including the gnocchi potato dumplings topped with basil pesto, chopped tomatoes and grated Parmesan cheese ($14) or the chicken alfredo with a grilled chicken breast over fettucine ($14).
Some customers have expressed frustration in online reviews that Angelo's sticks to its reservation system and turns away customers at times.
But the history of the building that Angelo's has occupied for the last few years suggests the chef may have his reasons.
The kitchen here is small. A restaurant that formerly occupied the site closed after sometimes accepting too many customers at once and failing to care for them all properly.
Questions? Comments? Contact LENS Editor Robin Nichols at (209) 546-8274 or firstname.lastname@example.com.


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Ward Eight Recipe
What with the third debate, Joe the Plumber, and all the heat associated with the closing days of the election, a person could need a drink or two. If that's the case, consider this a campaign-related concoction.
The Ward Eight purportedly dates back more than a century, to a time when politics could be truly bare-knuckle. Rumored to have been created at the Locke-Ober (the second oldest restaurant in Boston) to celebrate the victory of Martin Lomasney's 1898 campaign for a seat representing Boston's Eighth Ward--a celebration that suitably took place the night before the election--the Ward Eight is a simple twist on a whiskey sour.
Wait, did I say simple? When it comes to politics, nothing is simple, and by incorporating fresh OJ and a little grenadine into the venerable sour, the Ward Eight rises above the ordinary. With more than two weeks left yet until the election, you may want to keep a pitcher of these close at hand.
- 2 ounces rye whiskey
- 3/4 ounce fresh lemon juice
- 3/4 ounce fresh orange juice
- 1 teaspoon grenadine
Combine ingredients in a cocktail shaker and fill with ice. Shake well for 10 seconds and strain into chilled cocktail glass. Garnish with a campaign button.
This post may contain links to Amazon or other partners; your purchases via these links can benefit Serious Eats. Read more about our affiliate linking policy.


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In this problem-based data analysis activity, students identify trends and make predictions about the possible influence of climatic factors and vegetative growth on macro invertebrates. Step-by-step instructions for use of the MY NASA DATA Live... (View More) Access Server (LAS) guide students through selecting a data set, importing the data into a spreadsheet, creating graphs, and analyzing data plots. The lesson provides detailed procedures, related links and sample graphs, follow-up questions, extensions, and teacher notes. Designed for student use, MY NASA DATA LAS samples micro datasets from large scientific data archives, and provides structured investigations engaging students in exploration of real data to answer real world questions. (View Less)
Materials Cost: Free per student


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BRUSSELS (Reuters) - Serbia's ambassador to NATO jumped to his death from a multi-storey carpark at Brussels airport, officials said on Wednesday, and Serbia said it was investigating the incident.
Branislav Milinkovic, 52, jumped to his death during a conference of NATO foreign ministers, but officials did not make any connection between the meeting and his suicide.
"We are shocked and we are investigating all circumstances" surrounding the ambassador's death, said a Serbian Foreign Ministry official who asked not to be named.
"We have no clues about what could prompt Milinkovic to do that. He was a good man," the official said.
NATO Secretary-General Anders Fogh Rasmussen was "deeply saddened by the tragic death of the Serbian ambassador," who was highly respected, said an alliance spokeswoman.
Brussels prosecutor's office said: "We can be sure that it was a suicide, therefore we are not investigating any further."
The Serbian Foreign Ministry praised Milinkovic as a distinguished diplomat and jurist who would be "remembered as a skilled diplomat, an intellectual and a noble man."
Milinkovic was appointed ambassador to NATO in 2009 but had already been based in Brussels since 2004 as an envoy from the now defunct state union of Serbia and Montenegro.
Serbian tabloid newspaper Kurir reported that Milinkovic jumped around 10 meters (30 feet) in the presence of Serbia's assistant foreign minister for security policy, Zoran Vujic.
The report, which could not immediately be confirmed, quoted an unnamed foreign ministry source as saying: "It's possible the man was depressed and that nobody had noticed."
(Reporting by Robert-Jan Bartunk in Brussels and Aleksandar Vasovic in Belgrade; Writing by Sebastian Moffett; Editing by Jon Boyle)


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Your privacy is important to us. We have updated our privacy policy to better explain how we use data on this site. Read it here
"Star Trek: Into Darkness," which opens this week, marks the 12th entry in the long-running sci-fi franchise.�In anticipation of what is expected to be one of the summer's biggest blockbusters, we boldly go and attempt to rank the "Star Trek" films that came before.�We're sure true fans will find plenty to disagree with and probably consider switching their verbal phasers from stun to kill.�Here's our list from worst to first. So as Capt. Jean Luc-Picard would say: "Engage!"��11. "The Final Frontier" (1989)�Spock's half brother, or cousin, or old roommate from the Vulcan Science Academy – it really doesn't matter, because the plot is so awful – hijacks the U.S.S. Enterprise and steers the ship into the center of the galaxy to search for God. What the crew discovers isn't a divine being, but an alien trapped on a planet who wants to use the Enterprise to escape. Fans find a super massive black hole of a movie that nearly drains their love of the franchise.�Why it's ranked last: Maybe it was because William Shatner directed it and his ego was spiraling more out of control than usual. Maybe a great idea got lost in the dozens of rewrites the script went through. Whatever the reason, the movie was a muddled mess that lacked a consistent tone, a true galactic threat and the qualities that make Trek great.�Best moment: Kirk, Spock and McCoy go camping in Yosemite National Park. Seriously, this should've been the whole movie.��10. "Nemesis" (2002)�The last film featuring the "Next Generation" crew, who square off with a villain named Shinzon, played by a young Tom Hardy wearing an outfit that looks as if it was stolen from the set of "The Matrix." Anyhow Bane ... er, Shinzon, seeks to destroy Capt. Jean Luc-Picard. The motive: Shinzon is Picard's clone and he's got existential angst because of it. Um, what? This movie actually got made?�Why it's ranked here: Producers promised an awesome adventure. Instead we get a few scenes of Picard and Shinzon sharing a pot of Earl Grey tea and a plot that's basically a retread of a more well-regarded "Trek" film. And what's this business about a Picard clone?�Best moment: The Enterprise rams Shinzon's ship. Fans are amazed for, like, two seconds.��9. "The Motion Picture" (1979)�The first film in the franchise features a sentient alien probe threatening Earth. The Enterprise crew responds, spending most of the film's running time talking in undecipherable technobabble and reacting to what they see on the starship's view screen.�Why it's ranked here: It felt as if the producers put most of their budget into the special effects, forgoing the humor and humanity that were the hallmarks of the original series.�Best moment: 1980s B-movie actress Persis Khambatta gets kidnapped and turned into a robotic probe, which improves her acting dramatically for the second half of the movie.��8. "The Voyage Home" (1986)�Yet another alien probe travels to Earth and tries to communicate with humpback whales. The probe doesn't find any – because they're extinct in the future – and begins to inadvertently destroy the planet. So Kirk and crew travel back in time to1986 San Francisco to get some whales, which admittedly sounds ridiculous but doesn't turn out to be a "Final Frontier"-level train wreck after all.�Why it's ranked here: The film is horribly outdated when watched today. It came out during a time when Live Aid, Farm Aid and Greenpeace were all the rage and The "Voyage Home's" "Save the Whales" message seems hokey in the context of the rest of the "Trek" universe.�Best moment: A punk rocker flips the bird at Spock and Kirk. Spock gives him the Vulcan neck pinch.��7. "Generations" (1994)�An obsessed scientist named Soran wants to desperately return to something called the Nexus and he's willing to blow up a planet to do it. Capt. Picard, somehow forgetting all the hand-to-hand combat prowess he displayed during the "Next Generation's" run on TV, enlists the help of Capt. James T. Kirk to help him defeat Soran.�Why it's ranked here: The first "Next Generation" film was serviceable because it brought Picard and Kirk together. But it also wasn't that great because dozens of other "TNG" episodes were far better than this film and SPOILER ALERT Kirk dies in a way not befitting the most awesome Starfleet captain who ever lived.�Best moment: The Enterprise crash lands on a planet. Yes, the sequence was absolutely amazing.��6. "Insurrection" (1998)�Another "TNG" outing and this one's the most underrated in the entire film franchise despite a plot about a planet that bestows eternal youth and some villains who use the "Trek" equivalent of botox trying to destroy it. But Picard disobeys orders and drags his crew to help him save the populace. Among whom is a woman who happens to be about 500 years of age but looks 40, that Picard kinda has the hots for.�Why it's ranked here: It's pretty decent because it's "TNG" crew at their best, showcasing the friendship, humor and teamwork they were known for during their TV run. Fans might have felt let down because its scale was smaller than the "TNG" film that came before it. And yes, it did feel like a glorified television episode. But its themes and action set pieces rival any in the film franchise.�Best moment: The Planet Of Youth forces Worf to relive Klingon puberty which is as horrifying and hilarious as you would expect.��5. "The Search for Spock" (1984)�The surviving crew of the Enterprise, still reeling from the havok that Ricardo Montalban and his heaving chest wreaked upon them in the previous film, suspects that (SPOILER ALERT) Spock isn't dead and was somehow resurrected. Because Vulcans, no matter how logical they are, can somehow illogically come back to life.�Why it's ranked here: It's a good, but not great, "Trek" movie because it continues one of the best Trek story lines conceived. The Klingons, the warrior race and arch-nemeses of Kirk, are once again the main villains. And Kirk hits the self-destruct button on the Enterprise.�Best moment: Christopher Lloyd, speaking with the same inflection he had as Doc Brown in "Back to the Future," plays the main Klingon bad guy and chews up the scenery.��4. "Star Trek" (2009)�The reboot the franchise sorely needed after the disaster that was Nemesis. Director J.J. Abrams takes the helm. A new batch of younger actors portray the iconic members of the Enterprise. Eric Bana plays troubled Romulan Nero who wants to destroy every planet in the Federation. And Leonard Nimoy reprises his role as Spock. What's not to like?�Why it's ranked here: Fans were blown away because this marked the moment when Star Trek became a bonafide summer blockbuster. Sure, great films came before it, but the reboot was epic in scale and nearly every scene is packed with something awesome, whether it was callbacks to previous movies, the new cast channeling the old or the most breathtaking action sequences Trek ever had.�Best moment: Kirk, Sulu and a redshirt named Olson make a space jump onto a moving platform. Olson bites it in a spectacular fashion totally befitting a redshirt.��3. "First Contact" (1996)�The Next Generation's greatest enemy, the cybernetic organisms known as the Borg, travel to the past to assimilate Earth. Picard, still suffering from PTSD because he once was turned into a Borg drone, jettisons the decorum of being a Starfleet captain and goes on a mission of vengeance. Plus, fans get to see the origins of the Federation.�Why it's ranked here: It's one of the most thrilling "Treks" ever because it takes the most chilling adversary from the television series, places the Enterprise crew in grave peril and shows them blasting their way out of it. And they still have time for funny dialog and awesome jokes. The subplot involving warp drive inventor Zefram Cochran is, as Spock would say, equally fascinating.�Best moment: When Cochran asks the Enterprise crew, "So you're all astronauts on some sort of ... star trek?"��2. "The Wrath of Khan" (1982)�An adversary from Kirk's past, genetically-engineered superhuman Khan Noonien Singh, returns to seek vengeance when former Enterprise crewman Pavel Chekov mistakenly gives Khan a means to escape his exile. Khan then uses a MacGuffin called the Genesis device to threaten the universe and (SPOILER ALERT) force Spock to sacrifice himself to save his friends.�Why it's ranked here: OK, let's get it out of the way, if you're a fan, you're probably upset "Khan" isn't No. 1. Fans routinely rank this the greatest of all "Trek" films. It resurrected the franchise after the plodding "The Motion Picture," it gave Kirk a worthy antagonist, it addressed the age of the original crew in a touching way and its climactic battle in a nebula is phenomenal. But the seriousness of the film is almost undermined by Montalban's over-the-top performance and its pace slows to a crawl at some points. It's great, but Trek, as a film franchise, was still finding its footing at this point. Everything that's awesome about the series culminates, and soars, with the last film featuring the original crew – which happens to be our top pick.�Best moment: "Khaaaaaaaaaaaannnnnn!" It's a meme. Google it.��1. "The Undiscovered Country" (1991)�The Klingon's homeworld is on the verge of annihilation and the Enterprise crew must overcome their biases and hatred of their greatest enemies in an effort to forge a lasting peace. But a conspiracy against the peace accord is brewing and Kirk and Spock race to uncover the plot.�Why it's ranked here: It's the best Trek movie ever because it has an intense and vastly entertaining murder-mystery plot. It's an allegory on the fall of communism and deals with prejudice and xenophobia head on. It reveals the souls of one of "Trek's" best adversaries. Its pacing is perfect. It's a fantastic send off for the original crew and a great lead-in to the "Next Generation." And it has the qualities that all of "Star Trek" is built upon: optimism, a sense of discovery and a vision of the future we all can live in.�Best moment: Spock mind-melding with his protege Valeris (Kim Cattrall), so he can learn of an assassination attempt, is one of the most dramatic "Trek" scenes ever.��


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ABC German 1.3
More then just card matching game, ABC German is powerful alphabet learning tool for toddlers and preschoolers. When you child tap on a card as it flips over the letter and a word that starts from that letter is pronounced. As they match two pairs they are rewarded and they do like to get rewarded making them match more and more letters. After a while, not only does it help your child learn their German ABC, but also helps them rapidly build...


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This calendar shows all activities, meetings and services in and around St Peter's. You can skip to previous and future months, and hover over events of interest to see more information.
Events for January 30, 2018 › Regular Services
Events Search and Views Navigation
8:00 am
Morning Prayer
Our daily short morning serviceFind out more »
5:00 pm
Evening Prayer
Our daily short evening serviceFind out more »


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40% Saponins
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Tribulus terrestris is a natural herb extract containing atleast 40% saponins.Tribulus terrestris is actually a plant belonging to the Caltrop Family, primarily found in North America. But also widely distributed around the world.
Our tribulus has been engineered to form an easily swallowed convenient capsule. This product can be taken from 1- 3 times throughout the day.
This supplement is ideal for anyone who participates in regular exercise looking to maintain strength and lean muscle mass
Please note that the labelling on this product is provided in English as a minimum. French, Italian, German, Spanish, Danish, Swedish and Finnish may also be present on a product by product basis.
Consume 1 capsule, 1-3 times daily. Best taken with food.
Do not exceed the stated recommended daily dose. This product should not be used as a substitute for a varied, balanced diet. Keep in a cool dry place out of direct sunlight. Not suitable for vegetarians. Store out of the reach of young children.
Tribulus Terrestris Powder (40% Saponins), Capsule (Gelatin), Bulking Agent (Dicalcium Phosphate), Anti Caking Agents (Silicon Dioxide, Magnesium Stearate).
Made in a facility that handles Milk, Soy, Egg, Gluten and products thereof.
Serving Size - 1 Capsule
Servings Per Container - 100 (100 Capsules), 300 (300 Capsules)
|Per Serving
|Tribulus Terrestris
|300 mg
2 reviews
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Great stuff when compared to the traditional brands sold my other retailers. Does as it should by helping with endurance, energy and libido when cutting down and preparing for a show. Goes Well With:MyThermo Xtreme CLA L-Carnitine
Great price compared to other sites and I have found it very effective.Goes Well With:Water


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The Chinese Medicinal Herb Farm
A Cultivator's Guide to Small-Scale Organic Herb Production
Foreword by Steven Foster
Contributions by Sean Fannin
A leading light in the field of medicinal herb cultivation, The Chinese Medicinal Herb Farm is the first cultivation guide of its kind, and presents invaluable information for growers interested in producing high-quality efficacious herbs in all climates of the US, with the historical connectedness of ancient practitioners.
It has become increasingly important-especially as the market for herbal medicine continues to grow-that we transition to local and domestic medicinal cultivation. Increasingly there are concerns in regards to not only the quality but the purity of imported herbs, and wild herbs picked for medicinal purposes are ever more endangered than in past years both at home and abroad.
Peg Schafer, longtime grower and teacher, guides readers with information on propagating, cultivating, and harvesting Chinese herbs, and presents fascinating new scientific data that reveal the age-old wisdom of nature and the traditional systems of Chinese medicine. Through 79 detailed herb profiles–all tested and trialed on Schafer's certified organic farm-Schafer offers easy-to-follow information, suitable for both growers and practitioners, for growing efficacious wild-simulated herbs. Also included is important information on species conservation, crop integration, and how to avoid the introduction of invasive species. Sidebars on traditional medicinal uses for each herb and delicious recipes are also featured throughout.
Vegetable and CSA farmers will find this book of great interest for adding value-added crops to their repertoire, and beginner growers looking to incorporate medicinals into their gardens will find this an invaluable guide to understanding where herbal medicine comes from, and will make eating-your-medicine more accessible than ever.
Reviews and Praise
Book News-
Schafer, affiliated with the Chinese Medicinal Herb Farm in Petaluma, California, co-founded the first U.S. company to offer organic, domestically grown Chinese medicinal herbs. In this guide for Chinese medicine practitioners and organic farmers, she gives advice on organically growing and harvesting 79 medicinal herbs. Most of the herbs are used in Chinese medicine, but a few belong to the Ayurvedic tradition. The first section of the book gives background on herbal traditions, risks to the future of herbalism, and conservation and global trade in medicinal plants. This section also gives general advice on cultivation in the nursery, garden, and field, and on harvesting, drying, storing, and shipping herbs, collecting and saving seeds, and selling herbs. The book then provides profiles of 79 herbs. Each herb entry gives a plant description, advice on propagation and planting, a list of suitable plant companions, and a brief summary of medicinal uses, plus notes on field production, pests and diseases, and harvest and yield. Each entry also includes a couple of color photos of plants in the field and the roots, flowers, or other parts when processed for medicinal use.
More Reviews and Praise
"Comprehensive" best describes Schafer's specialized resource. She begins, appropriately, with a discussion of small-scale cultivation as a way to protect the environment and be part of the international trade in medicinal plants. The growth of herbal trade parallels the increase in the number of Americans exploring acupuncture and other elements of traditional Chinese medicine, so this guide will meet the rising do-it-yourself interest in growing medicinal herbs. Schafer's easily understood instructions are accompanied by boxed inserts of important tips, charts and tables, and photographs. Most of the book is dedicated to 79 detailed herb profiles with growing information and medicinal uses. Also provided are plant and medicinal name cross-references; hardiness-zone maps with a China-U.S. latitude overlay; resources for herb seeds and plants; recommended readings, listings of websites, and herbal and conservation organizations; and an all-important glossary of horticultural, medicinal, and Chinese terms. This genuinely unusual, authoritative manual will likely be in brisk demand.
"For the practitioner of Chinese medicine, The Chinese Medicinal Herb Farm is a teacher, drawing us closer to the herbs we use. For the casual gardener, it is a handbook for growing fresh Chinese herbs as part of a healthy diet. For anyone who has an interest in growing their own Chinese herbs, Peg Schafer gives us a new reason to look forward to spring."--Andrew Ellis, author of Notes from South Mountain: A Guide to Concentrated Herb Granules
"Peg Schafer, the most experienced Chinese medicinal herb grower in North America, charts a new course in Chinese medicinal plant cultivation by providing the guidance needed to grow the most important of these herbs domestically. This book offers more than just cultivation tips, but also an assurance of proper plant identification, optimal growing and harvesting conditions, freshness of materials, and the ability to access Chinese medicinals with the lowest carbon footprint possible."--Roy Upton, Executive Director, American Herbal Pharmacopoeia
"Peg Schafer understands in more ways than one that good health springs from the land. Herbs from the Chinese tradition perfectly complement more familiar healing plants. The concept of "regional medicine farms" resonates so well with the growing desire to eat more locally. But of course! We are what we eat, and that includes the medicinal plants that work with our bodies to create wholeness. Every plant person will instantly recognize the gift waiting within this book-Schafer shares many astute observations of how each plant garners medicinal oomph, what she calls the vital qi (chi) of each herb. And that's the right sort of inspiration to launch any thinking gardener!"--Michael Phillips, author of The Holistic Orchard, and co-author Nancy Phillips of The Herbalist's Way
"Peg Schafer is the best artisanal grower I know. For this book, she has distilled the knowledge of the small group who, over the past two decades, has pioneered North American production of Chinese medicinal herbs, and tested it through direct experience. This book clearly explains the whys as well as the how-tos, and delivers information into the eager hands of all perennial polyculturalists who will grow us a post-peak oil healthcare system; it is a gift to us all."--Jean Giblette, owner, High Falls Gardens and co-founder, LocalHerbs.org
"This is by far the most detailed and thorough book that addresses the urgent issue of organic cultivation and processing of Chinese herbs. It will have a profound effect on future land use, herb availability, pesticide burdens, and sustainability in a field that is expanding rapidly around the world. I can't stress enough how valuable and rare this information is to practitioners and users of Chinese herbal medicine. I highly recommend this book for all TCM herbalists, as well as gardeners and farmers who want to learn the art of the organic cultivation of Chinese medicinals."--Bill Schoenbart, L.Ac., D.A.O.M
About The Author
|324 pages
|Book Art:
|Color illustrations and maps
|8 x 10 inch
|Chelsea Green Publishing
|Pub. Date:
|November 30, 2011
Available In/Retail PricePaperback, 324 pages, $34.95
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Listen to today's episode of StarDate on the web the same day it airs in high-quality streaming audio without any extra ads or announcements. Choose a $8 one-month pass, or listen every day for a year for just $30.
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Robert Hooke
Today marks the birthday of one of the world's most versatile natural philosophers -- the British scientist and inventor Robert Hooke. He was born 375 years ago today.
Hooke entered Oxford University at the age of 17. In his early twenties, he discovered what's known today as Hooke's law of elasticity, which says that the stretching of a solid mass is proportional to the force applied to it.
By age 30, Hooke was curator of experiments for London's Royal Society -- the first true scientific organization in the world. His prolific experiments, demonstrations, and writings helped to keep the prestigious group intact and financially solvent for many years. His greatest work, Micrographia, which was published in 1665, began the study of insect anatomy. Perhaps most important, it suggested for the first time that the microscope might be useful in biological study.
Hooke's inquiring mind also turned to the heavens. In 1664, he observed a dark spot in Jupiter's southern hemisphere. It's the first recorded mention of Jupiter's Great Red Spot, which astronomers didn't formally catalog for another 200 years.
Hooke was one of many scientists who attempted to solve the mystery of planetary motion. His pioneering work was an inspiration to Sir Isaac Newton, who ultimately developed a theory of universal gravitation. But it was also the source of a scientific quarrel that turned two of the greatest scientists of their time into lifelong enemies.
Script by Laura Tuma, Copyright 1995, 2010
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