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Forklifts for Sale, NewUsed Lift Trucks & Material Handling Equipment Dealers MH Equipment Ohio
New & Used Forklifts For Sale. Rentals, Training, Parts, Service, Fleet and Other Construction-Material Handling Solutions From MH Equipment
Welcome to MH Equipment, your local authorized Hyster and Yale* dealer. Each and every day we work hard to be great stewards of our customer's resources by providing the highest quality products and exceptional service. Here at MH, we always carry top quality material handling equipment to meet our customer's needs including a broad selection of Hyster forklifts, Yale lift trucks, aerial work platforms, floor cleaning equipment, personal transporters, rail car movers and more industrial, janitorial and material handling equipment. In addition, all our branches provide fleet, parts, rental, repair and service solutions to the valued customers that rely on us each day.
MH Equipment: Dealers Servicing The Leading Forklift Brands
As a leading materials handling solutions provider, we are proud to serve the Midwest from our locations in Illinois (Danville, Decatur, Peoria & Ottawa), Indiana (Indianapolis & Evansville). Iowa (Cedar Rapids, Davenport, Des Moines, Dubuque, Eldridge, Ottumwa, Sioux City & Waterloo), Kentucky (Louisville, Calvert City & Bowling Green, Lexington), Missouri (Cape Girardeau-Scott City & St. Louis), Nebraska (Grand Island & Omaha), Ohio (Cincinnati, Columbus & Dayton); Erie, Pennsylvania and Charleston, West Virginia. You can find the contact information and location of each of our dealers on our Locations page.
When you visit a MH Equipment dealership you can be sure that our machines will fulfill any job specification. We carry the leading brands in material handling including Hyster, Yale*, Mariotti, JCB, Rico, Cascade, Cushman, Genie, Motrec, Navigator, PowerBoss, and Rail King. All of our dealers feature a vast inventory of quality new and used equipment to help fulfill any need.
Not only can you shop for a new or used fork lift, lift truck, aerial work platform, floor cleaning machine, rail car mover and more material handling machinery, but we also strive to provide the best service in the industry. Each of our locations in Illinois, Indiana, Iowa, Kentucky, Missouri, Nebraska, Ohio, Pennsylvania and West Virginia are accessible 24 hours a day and our top of the line service staff will be available to help with any need you have. Whether you need installation and prep work or maintenance and repair, our skilled staff is committed to providing the service and support you have come to expect from MH Equipment.
If attachments or parts are what you need we have a vast selection of types including, clamps, roll handlers, forklift batteries and chargers, and parts for all makes and models of material handling equipment. Our incredible variety of aftermarket products is sure to have the solution to whatever is needed at your warehouse or other facility.
At MH Equipment, you can also rent industrial and material handling equipment. You'll find every rental forklift. lift truck, AWP, industrial sweeper unit or other piece of machinery well-serviced and ready to work when you need it. We are always happy to facilitate any rental program to ensure it fits your requirements — from renting or leasing to short-term or long-term — and we carry all the leading brands in our rental fleet like Hyster, JCB, Mariotti and Yale*.
Forklift Operator Training
Of course, we also provide Forklift Operator Training. We focus on keeping safety as our highest priority and we can train your operators to be more productive in a safer manner. Training can be conducted at your location or at one of our facilities.
Fleet Management
MH Equipment also offers impressive fleet management solutions and software for any operation. We will help you improve efficiency and increase the return on investment from your fleet of lift trucks, forklifts and other equipment. Increasing the profitability of your operation is essential as competition increases across all industries so try our demo and see how we can help you decrease inefficiency.
So visit one of our locations across the Midwest today for quality new and used material handling equipment or use our interactive Web site to shop our inventory, set up a service appointment or learn more about fleet management solutions.We live by the motto that People Matter, Passion Inspires and Purpose Unites and these virtues help ensure you will be happy you went with MH Equipment for all your equipment needs!
*Yale lift trucks are available in our St. Louis, Cincinnati and Dayton areas at this time. For information on purchasing Yale lift trucks outside the St. Louis, Cincinnati or Dayton areas, please contact us and we will forward you to the appropriate Yale equipment dealer.
Call MH Equipment today at 888-564-2191 to learn more about our extensive line of material handling products and services!


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NEW YORK (AP) — A money manager the government says set a record by making $50 million on a single trade based on inside information went on trial Tuesday as a prosecutor promised to take jurors "into the world of hedge funds."
Anthony Chiasson, a co-founder at former hedge fund group Level Global Investors, is standing trial on insider trading charges along with Todd Newman, a Needham, Mass., hedge fund portfolio manager. Lawyers for the men said they did nothing wrong, relying on research conducted by analysts that the government now says were corrupt.
Assistant U.S. Attorney Richard Tarlowe said both men benefitted from a "corrupt chain of people who shared secret inside information" with one another.
He said Chiasson made about $50 million and Newman recorded a $2.8 million profit for his hedge fund when both learned that Dell Inc. was going to disappoint investors when it announced in the summer of 2008 that gross margins were lower than expected. Tarlowe said prosecutors would show jurors emails, instant messages, summaries of stock trades and phone records to support the testimony of four individuals who were part of the insider trading chain.
The witnesses "will give a unique window into criminal activity that only a participant can provide," he said.
At a news conference in January, U.S. Attorney Preet Bharara said the Dell trades represented the largest transaction ever prosecuted in Manhattan. He said it was part of a $78 million scheme.
At one point during his opening statement, Tarlowe told jurors: "We will take you into the world of hedge funds."
Chiasson's defense lawyer, Reid Weingarten, suggested he will do the same by describing a highly competitive hedge fund industry that relies on analysts with inflated egos who compete ferociously to get information that others don't have, sometimes through insiders at public companies and 6through other research.
"These people can become famous," he said of the analysts, including one accused in the scheme who was paid $2 million in 2008. "They are highly, highly paid."
Chiasson also was paid well, Weingarten said, making "A-Rod-type money" in 2007, a reference to the more than $20 million annual salary of New York Yankees slugger Alex Rodriguez.
Weingarten said it was not unusual to get information from public companies that stage road shows and seek attention from analysts and others in a quest to raise money.
He blamed Sam Adondakis, a former Level Global analyst who has pleaded guilty in the case, for his client's trouble, saying he was leading a double life by portraying himself as a responsible analyst to Chiasson and others while making dirty deals to get information he should not have.
The lawyer said Chiasson's Dell bet was consistent with his contrarian nature and common sense, since Dell's stock had run up unreasonably before its drop after earnings. He also said the Dell trade was not unusual for a $4 billion hedge fund.
Stephen Fishbein, Newman's lawyer, said his client had no idea that a corrupt analyst was feeding him inside information, since he disguised it as legitimate research.
He noted that Newman made more than 32,000 trades in 366 securities in 2008.
He said talking to company insiders was common in the industry and was "a perfectly acceptable way to do research."
Fishbein said he would prove through his client's trades, which included gains and losses in the same stocks, that he did not know secrets.
"Newman did not trade as if he was getting tomorrow's news today," he said.

subset: commoncrawl


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An F-35B Lightning II, attached to the "Avengers" of Marine Fighter Attack Squadron (VMFA) 211, launches from the flight deck of Wasp-class amphibious assault ship USS Essex (LHD 2) during a regularly scheduled deployment of the Essex Amphibious Ready Group (ARG) and 13th Marine Expeditionary Unit (MEU).
Photo via Trailblazer Firearms
T&P on Facebook
Looking for a great career? Or know another veteran, service member, or military spouse who is? Get started at Hirepurpose.


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Meet thousands of Granite singles through one of the best Granite online dating sites. Matchmaker.com has great instant messenger and live video Granite chat service for our members. Granite dating has never been easier with our show interest feature that will allow you to break the ice with attractive local singles.
Matchmaker.com has some great services for Granite singles looking for a longer term relationship. Besides our great Granite chat product with live video matchmaker users can send email messages to people in the area. The Granite dating scene can be hard to find the right person at times; however, we are here to help and our Granite online dating service is free to register.
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Carbon Fiber width 1.0m Hydrographic Film Water Transfer Printing Film Activator Hydro Printing Film
Product Description:
KOUE Water Transfer Printing Film
Questions you may concern
What is water transfer printing?
Answer: Water Transfer Printing (also known as water immersion printing, hydrographic printing, hydro dipping, hydro imaging and fluid imaging) is a 3D decorating process.
The Water Transfer Printing process is extensively used to decorate items that range from entire all-terrain vehicles and car dashboards to small items like bike helmets or other automotive trim. Films can be applied to all types of substrates including plastic, glass, wood, ceramic, stone and metal. For the most parts, if the item can be dipped in water, the hydro graphic process can be used.
What film patterns we have?
Answer: We have thousands of patterns including Carbon Fiber, Skull, Camouflage, Wooden, Marble& Stone, Animal Skin, Cartoon, Flower, Metal Brush, Decoration, etc. Many films are very popular in the whole world. We can also print your own design if you want.
What items can this technology apply to?
Answer: This process can be used on almost all 3D parts surface treatment, like car interiors, wheels, helmet, motorbike, x-box, furniture, shoes, soles, slippers, fishing tools, glasses, etc.
What width film we have?
Answer: We have films in 50cm to 100cm width.
How can place an order?
Answer: Please kindly send us an inquiry, or contact us on trademanager by Alibaba.
Here are details :
1) Please contact us, and we will send you our film catalogue by email.
2) When you get the catalogue, please select patterns you like, and list us pattern numbers and quantity respectively.
3) We will quote you the total soon after your list. Payment by T/T bank transfer, PayPal, Western Union, LC is ok.
4) We will ship your order by DHL, FedEx, EMS, UPS or TNT express in 1-5 days after releasing payment. You may get your cargo in 7-15 days after payment.
Selecting film on our official website: http://koue.en.alibaba.com
What kind of packing we use?
Answer: The film should be packed in a plastic bag.
Lay film face down on flat surface with a flat item such as a book on top for weight to protect paper from curling, then we pack the roll within plastic package and carton package outside.
Do we offer freight discount?
Answer: We will quote you freight at the discount price we get from express companies. There are big freight discount from DHL/UPS/TNT/FedEx for more than 20KGS (About400 sqms film) order.
Do we offer process support?
Answer: It's our honor if we can help you to start WTP business, we are glad to offer you process support. If you have any questions, just let us know.
Do we offer film activator?
Answer: We can offer activator to you. Activator is the key to WTP process. Please contact us, and you will get more than you need.
Can we print film at our own design?
Answer: We provide customized printing service. If you have any design, just send us picture in AI or CDR format. Kindly let us know the film width you would like to print, we will email you the detail of this service.
What if the shipping cargo were damage or shortage?
Answer: We will well wrapped with tapes, and pack the films in carton box, then we choose the best express company (TNT/UPS/FedEx/EMS) to deliver cargo to avoid shipping damage.
If you got damaged packing, please kindly let us know within 3 days. Before you open the box please take photos of the package, shoot weighting photos, and send us pictures. We will composite you soon after the damage or shortage confirmed.


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An arms company will join an existing, affiliated firm in Fort Smith and together they will undergo a $7 million expansion and add up to 120 jobs in the next five years, officials said Thursday.
Walther Arms will locate at Chaffee Crossing, where it will share a campus and business resources with Umarex USA, the Arkansas Economic Development Commission said in a statement. The manufacturing operations will include making components for airguns and firearms.
The commission said the companies hope to add between 70 and 120 jobs in the next five years.
"We are absolutely fired up to see Fort Smith become the home for the iconic Walther brand and company," Walther Arms and Umarex USA Chief Executive Officer Adam Blalock said in a statement. "My personal hope and objective is to see more manufacturing and jobs return to the USA in the coming years and what better place than Fort Smith!"
Umarex USA opened in Fort Smith in 2006 and has seen its sales volume double since moving its operations to the Chaffee facility in 2010.
"Fort Smith's excellent workforce helped convince Umarex and Walther to increase production here, and their overall Arkansas experience led to make our state their North American Headquarters," Gov. Mike Beebe said in a statement. "Success stories like this will help to influence other companies deciding where to invest for success."
Officials say some products being manufactured abroad will be shifted to Fort Smith in the expanded facility.


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Caring for you and your family means providing complete care, from preventive care to maintain good health to specialty care from highly trained physicians using the latest medical equipment. The Sutter Physicians Alliance is made up of two medical groups with more than 250 primary care doctors and more than 800 specialists located throughout the Greater Sacramento region. By working together, we ensure you have access to the care you need at the high standard of quality you deserve.
Our Medical Groups
Sutter Medical Group
Amador, Placer, Sacramento & Yolo Counties
Sutter Independent Physicians
Amador, Placer, Sacramento & Yolo Counties
Managing Your
Health Online
Current Users
My Health Online Login
New Users
Login with Access Code
Sign up/How to enroll
• E-mail my doctor
• View my lab results
• Refill my prescription
• Manage my family's health
• My medical record
• Schedule appointment
• Pay bills


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Bortezomib and Combination Chemotherapy in Treating Patients With Relapsed or Refractory Acute Lymphoblastic Leukemia
|The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
|ClinicalTrials.gov Identifier: NCT01769209
Recruitment Status : Active, not recruiting
First Posted : January 16, 2013
Last Update Posted : January 23, 2018
- Study Details
- Tabular View
- Results Submitted
- Disclaimer
- How to Read a Study Record
|Condition or disease
|B-cell Adult Acute Lymphoblastic Leukemia Ph Positive Adult Acute Lymphoblastic Leukemia Recurrent Adult Acute Lymphoblastic Leukemia T-cell Adult Acute Lymphoblastic Leukemia
|Drug: bortezomib Drug: doxorubicin hydrochloride Drug: pegaspargase Drug: vincristine sulfate Drug: dexamethasone Drug: cytarabine Drug: methotrexate
|Phase 2
I. Determine the response rate of bortezomib in combination with a chemotherapy backbone of doxorubicin (doxorubicin hydrochloride), vincristine (vincristine sulfate), PEG-asparaginase (pegaspargase), and dexamethasone in patients with relapsed/refractory acute lymphoblastic leukemia.
I. Determine progression free survival. II. Estimate the rate of complete response (CR) and CR with incomplete platelet recovery (CRp) after this re-induction compared to a historical baseline.
III. Estimate failure-free survival (FFS) and survival percent at 1 year compared to a historical baseline.
IV. Assess safety and tolerability of the study drug. V. Determine whether bortezomib induces reactive oxygen species (ROS) in circulating acute lymphoblastic leukemia (ALL) blast cells.
Patients receive bortezomib subcutaneously (SC) on days 1, 4, 8, and 11; doxorubicin hydrochloride intravenously (IV) on day 1; pegaspargase IV or intramuscularly (IM) on days 5 and 22; vincristine sulfate IV on days 1, 8, 15, and 22; dexamethasone orally (PO) daily on days 1-14; cytarabine intrathecally (IT) on day 1 and methotrexate intrathecally (IT) on day 15. Patients with central nervous system disease receive intrathecal treatment per investigator's discretion.
After completion of study treatment, patients are followed up every 3 months for up to 2 years.
|Study Type :
|Interventional (Clinical Trial)
|Actual Enrollment :
|18 participants
|Intervention Model:
|Single Group Assignment
|None (Open Label)
|Primary Purpose:
|Official Title:
|Phase II Study of Subcutaneous Bortezomib in Combination With Chemotherapy in Relapsed/Refractory Adult Acute Lymphoblastic Leukemia
|Study Start Date :
|March 2013
|Actual Primary Completion Date :
|September 30, 2017
|Estimated Study Completion Date :
|September 30, 2018
Experimental: Treatment (bortezomib, chemotherapy)
Patients receive bortezomib SC on days 1, 4, 8, and 11; doxorubicin hydrochloride IV on day 1; pegaspargase IV or IM on days 5 and 22; vincristine sulfate IV on days 1, 8, 15, and 22; dexamethasone PO daily on days 1-14; cytarabine IT on day 1 and methotrexate IT on day 15. Patients with central nervous system disease receive intrathecal treatment per investigator's discretion.
Drug: bortezomib
Given SC
Other Names:
Drug: doxorubicin hydrochloride
Given IV
Other Names:
Drug: pegaspargase
Given IV or IM
Other Names:
Drug: vincristine sulfate
Given IV
Other Names:
Drug: dexamethasone
Given PO
Other Names:
Drug: cytarabine
Given IT
Other Names:
Drug: methotrexate
Given IT
Other Name: MTX; amethopterin
- CR rate [ Time Frame: On day 29 at the end of induction therapy ]Response rates will be evaluated and accompanied by 95% confidence intervals using the binomial distribution. Response rate by categories will be calculated with 95% confidence intervals.
- Progression-free survival (PFS) [ Time Frame: From the start of treatment to disease progression or death, whichever comes first, assessed up to 2 years ]Analyzed using Kaplan-Meier survival analysis and accompanied with 95% confidence interval.
- CR and CRp rate after re-induction [ Time Frame: Up to 2 years ]Compared to a historical baseline.
- Failure-free survival (FFS) [ Time Frame: At 1 year ]Analyzed by the Kaplan Meier method. Compared to a historical baseline.
- Survival percent [ Time Frame: At 1 year ]Compared to a historical baseline.
- Incidence of adverse events as assessed by Common Terminology Criteria for Adverse Events (CTCAE) version 4.0 [ Time Frame: Up to 45 days after completion of treatment ]Toxicity profile will be presented by rate of overall toxicity and rates of grade 3 or 4 toxicities analyzed separately and combined. Adverse events will be summarized and accompanied by 95% confidence intervals using binomial distribution.
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies.
|Ages Eligible for Study:
|18 Years and older (Adult, Older Adult)
|Sexes Eligible for Study:
|Accepts Healthy Volunteers:
Inclusion Criteria:
- Voluntary written informed consent before performance of any study-related procedure not part of normal medical care, with the understanding that consent may be withdrawn by the subject at any time without prejudice to future medical care
Female subjects who:
- Are postmenopausal for at least 1 year before the screening visit, OR
- Are surgically sterile, OR
- If they are of childbearing potential, agree to practice 2 effective methods of contraception, at the same time, from the time of signing the informed consent form through 30 days after the last dose of bortezomib, or agree to completely abstain from heterosexual intercourse
Male subjects, even if surgically sterilized (i.e., status post vasectomy) who:
- Agree to practice effective barrier contraception during the entire study treatment period and through a minimum of 30 days after the last dose of study drug, OR
- Agree to completely abstain from heterosexual intercourse
- • The patient has relapsed or refractory B or T cell acute lymphoblastic leukemia that has progressed following at least one prior therapy. Ph+ patients are eligible. Relapsed ALL is defined in patients as the reappearance of leukemia cells in the peripheral blood or bone marrow or appearance of extramedullary disease after a complete remission. Refractory ALL is defined in patients as failure to achieve a complete remission after induction therapy. Complete remission is defined by <5% leukemia cells in the bone marrow with recovery of peripheral blood counts. Relapsed disease can be documented by bone marrow biopsy (>5% cells in the bone marrow) or by flow cytometry in the peripheral blood or biopsy of extramedullary disease.
- Must have received at least one (1) line of prior systemic therapy that may NOT have included VELCADE (bortezomib); patients who have undergone autologous/allogeneic stem cell transplantation are eligible
- Transplant eligible patients are eligible
- Eastern Cooperative Oncology Group (ECOG) performance status 0-2
- No poorly controlled intercurrent illness including, but not limited to, ongoing or active infection, poorly controlled diabetes, symptomatic congestive heart failure, or psychiatric illness that in the opinion of the investigator would limit compliance with study requirements
- Aspartate aminotransferase (AST) and alanine aminotransferase (ALT) < 2.5 x upper limit of normal
- Total bilirubin =< 1.5 x upper limit of normal (ULN) unless elevation is deemed due to leukemia infiltration. In these patients, dose modifications may be required based on standard guidelines.
- Patients must have adequate renal function defined as creatinine clearance of >= 30 ml/minute (Cockcroft-Gault)
Exclusion Criteria:
- Patient has > 1.5 x ULN total bilirubin
- Patient has >= grade 2 peripheral neuropathy
- Patient had myocardial infarction within 6 months prior to enrollment or has New York Heart Association (NYHA) class III or IV heart failure, uncontrolled angina, severe uncontrolled ventricular arrhythmias, or electrocardiographic evidence of acute ischemia or active conduction system abnormalities; prior to study entry, any electrocardiogram (ECG) abnormality at screening must be documented by the investigator as not medically relevant
- Patient has hypersensitivity to bortezomib, boron, or mannitol
- Female subject is pregnant or lactating
- Serious medical or psychiatric illness likely to interfere with participation in this clinical study
- Diagnosed or treated for another malignancy within 2 years of enrollment, with the exception of complete resection of basal cell carcinoma or squamous cell carcinoma of the skin, an in situ malignancy, or low-risk prostate cancer after curative therapy
- Participation in clinical trials with other investigational agents not included in this trial throughout the duration of this trial
- Radiation therapy within 3 weeks before randomization; enrollment of subjects who require concurrent radiotherapy (which must be localized in its field size) should be deferred until the radiotherapy is completed and 3 weeks have elapsed since the last date of therapy
- The patient has been exposed to >= 350mg/m^2 of anthracycline (doxorubicin equivalent)
- The patient has a left ventricular ejection fraction of < 40%
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01769209
|United States, California
|Stanford University, School of Medicine
|Stanford, California, United States, 94305
|Principal Investigator:
|Michaela Liedtke
|Stanford University
|Responsible Party:
|Michaela Liedtke, Assistant Professor of Medicine, Stanford University
|ClinicalTrials.gov Identifier:
|NCT01769209 History of Changes
|Other Study ID Numbers:
NCI-2012-03094 ( Registry Identifier: CTRP (Clinical Trial Reporting Program) )
|First Posted:
|January 16, 2013 Key Record Dates
|Last Update Posted:
|January 23, 2018
|Last Verified:
|January 2018
Additional relevant MeSH terms:
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Leukemia, Lymphoid
Neoplasms by Histologic Type
Lymphoproliferative Disorders
Lymphatic Diseases
Immunoproliferative Disorders
Immune System Diseases
Dexamethasone acetate
Liposomal doxorubicin
Anti-Inflammatory Agents
Autonomic Agents
Peripheral Nervous System Agents
Physiological Effects of Drugs
Gastrointestinal Agents
Hormones, Hormone Substitutes, and Hormone Antagonists
Antineoplastic Agents, Hormonal


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Rex Activity Center recognized by Colorado Preservation, Inc.
The Colorado Preservation, Inc.'s 23nd Annual Dana Crawford Award Celebration, in May at the History Colorado Center, honored Adams State University's efforts to preserve the exterior of the historic Rex Activity Center.
Adams State Bill Mansheim, vice president for finance and governmental relations, attended the event and accepted the CPI's State Honor Award for the historic building's exterior rehabilitation, completed with assistance from History Colorado's State Historical Fund. The award was presented during the annual award ceremony, which was established in 1988 and recognizes accomplishments in the areas of preservation, rehabilitation, promotion, philanthropy and leadership.
Rex Activity Center History
Constructed in 1938-39 through Public Works Administration project funds, Rex Activity Center was originally built as Adams State's first free standing gymnasium. The college's first president, Dr. Ira Richardson, wished to acknowledge and celebrate the Hispanic culture of the San Luis Valley, and had the gym, along with the President's Residence, now known as the Marvel House, and three dorms built in the Spanish Colonial Revival style, by the accomplished Denver architect, the late William Norman Bowman. The former dorm buildings have been demolished.
The Rex, named for Clifford P. Rex, who served on the Board of Trustees of State Normal Schools from 1925-1949, stood vacant for 30 years after construction of Plachy Hall. After a capital fee was passed by students in 1995, Rex was remodeled for an on-campus fitness center.
In 2007, a State Historical Fund grant of $25,000, funded by limited stakes gambling taxes, supported a planning project to evaluate and analyze the deteriorating stucco, paint and the methods of the early construction, as well as later patch jobs on the exterior of the Rex. The original appearance of the building was researched and methods were developed for the safe removal of detrimental materials and application of new materials to replicate the appearance and function of the originals.
In 2009, Adams State received an additional $198,000 from the State Historical Fund for exterior improvements to Rex, including a new stucco finish coat in the original texture and brick cleaning and repair. Adams State matched the grant with $100,000. Architect Belinda Zink created the construction documents and supervised the exterior rehabilitation of the Rex. Tawney Becker, now Adams State grant specialist, assisted with writing the grant.


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RICHMOND, Va. (AP) — The door opened Monday for tens of thousands of nonviolent felons in Virginia to regain the right to vote, with state officials outlining steps each will have to take to recapture their basic civil rights.
Gov. Bob McDonnell has said up to 100,000 disenfranchised felons ultimately could be added to the voter rolls, serve on a jury or hold political office.
"For past offenders, our goal is to grant civil rights back to as many as possible," McDonnell said in a statement. "This is the right thing to do for all Virginians to help make the commonwealth a safer and better place."
A former prosecutor and attorney general, McDonnell said offering past offenders to opportunity to resume their lives as productive citizens, "we can better keep them from committing another crime and returning to prison." He called that step a move to thwart "prison expansion" and to promote "smart government."
The move by Virginia is part of a national trend as states recognize that the denial of basic rights to offenders serves little societal good, said Myrna Perez, deputy director of the Brennan Center for Justice.
"Legislatures across the country the country over the past 10 years have been making laws more expansive and more open," said Perez, who called Virginia's move "a welcome first step."
The task will not be easy. The state has no database of past felons and no electronic records were kept before 1995.
Secretary of the Commonwealth Janet Kelly said the "biggest challenge" has involved locating felons who have been out of the system for years or decades.
"We could easily find the felons who were currently in the system or who had previously expressed an interest in getting their rights back," Kelly said.
For the 500 to 700 felons who complete their sentences each month in the state, basic rights are to be automatically restored, provided they satisfy other requirements.
The state has added four workers to help process requests and locate others, aided by some additional funding and upgraded technology. The state will also work with such groups as the National Association for the Advancement of Colored People and the American Civil Liberties Union to reach out to nonviolent felons.
The Sentencing Project, a rights advocacy group, estimates that about 350,000 Virginians remained disenfranchised in 2010. Virginia was among six Southern states in which more than 7 percent of the adult population is disenfranchised, and one in five African-Americans are disenfranchised.
The Advancement Project, one of the groups that has worked with the state, said it was committed with them to helping spread the word. "Today marks the beginning of more Virginians having their voting and other civil rights restored than ever before," said the group's co-director, Judith Brown Dianis.
For nonviolent offenders to retain their civil rights, they must have completed their prison sentences, probation or parole; have no outstanding fines, restitution or court costs; and have no pending felony charges.
In Virginia, only the governor can restore a felon's civil rights. McDonnell had already streamlined the process and has restored the rights of more than 5,000 felons, more than any other previous administration.
While McDonnell had already eliminated a two-year waiting period for nonviolent felons, felons convicted of a violent crime will still have to wait five years and apply to regain their civil rights.
The American Civil Liberties Union of Virginia, while commending the governor for the progress in restoring voting rights, was critical of the pace of the state's efforts to restore rights to ex-prisoners — and other elements of the program. It said less than 10 percent of the 100,000 eligible nonviolent offenders would be able to vote in the upcoming election.
The ACLU and other advocates said the state also should work to restore the civil rights to violent offenders.
"We encourage our next governor to expand upon McDonnell's legacy and ensure that even more Virginians are eligible to vote," said Tram Nguyen of the Virginia New Majority, one group active on the issue.
The Secretary of the Commonwealth's office has a contact form on its website http://www.commonwealth.virginia.gov/ that's also available at probation and parole offices. By Aug. 1, a web-based form will allow for a direct submission of restoration or rights and a toll-free number (1-855-575-9177) has been established for those without computer access.
Steve Szkotak can be reached on Twitter at http://twitter.com/sszkotakap.
Brennan Center for Justice: http://www.brennancenter.org/


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I Can Do That: Corner Shelf
This handsome hanging storage unit is a snap to build with screwed butt joints.
By Megan Fitzpatrick
Pages: 84-85
From the November 2008 issue #172
Buy this issue now
This simple and casual storage unit offers a choice when it comes to stock selection. In the November 2007 "I Can Do That" column, we discussed an easy way to glue up panels using pocket screws ("Shaker Step Stool," issue #165). So you might wish to follow the steps outlined there to make panels for the backs, top and shelf.
But, you can also buy already glued-up panels of pine at the home center for just a little more cash outlay, so that's what I did for this project. My shopping trip for this corner shelf was quick and easy. I picked up two 24″ x 48″ pine panels, one pine 1″ x 8″ x 3′ for the sides, one pine 1″ x 2″ x 2′ for the rail, and two double hooks with a rubbed-nickel finish.
From the November 2008 issue #172
Buy this issue now


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For days and times for Mass, Confession and other regular liturgies and devotions, please see the schedule of worship services.
El Grupo de Oración en Español se reunirá a las 7 de la tarde en el salón de conferencias del Oeste.
All are welcome to adore our Lord in the Blessed Sacrament this First Friday. Exposition of the Blessed Sacrament is held following the 12:10pm Mass until 5pm in the Blessed Sacrament Chapel, located to the left of the sanctuary.
Always God's Children (AGC) is a Cathedral ministry that fosters Christian community and spiritual growth among persons who are gay, lesbian, or bisexual, as well as their friends and family members. AGC meets on the second Sunday of each month from September through May at 3:30pm in the West Conference Room.
All are welcome to adore our Lord in the Blessed Sacrament at a Eucharistic Holy Hour from 6 to 7pm. The Sacrament of Reconciliation will be available in English and Spanish during the hour.
New Catholics and "newer" Catholics are invited on the fourth Wednesday of the month for Mystagogy, or "learning about the mysteries" of our faith. Feeling called to join us?
Join us for our monthly Rosary for Life on Saturday, December 22 at 11:30am in the Cathedral.
Únase a nosotros por el Rosario Mensual por la Vidael sábado 22 de diciembre, a las 11:30 de la mañana en la Catedral.
Copyright © 2007–2018. All rights reserved.


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Charles W. Blackwell, 70, the Chickasaw Nation's Ambassador to the United States and the Director of Native Affairs & Development Group, died on January 2, 2013, in Rockville, Maryland, of respiratory complications following surgery.
Ambassador Blackwell was widely recognized for his advocacy for Tribal sovereignty, for zealously protecting the cultural integrity of Tribal Nations and in seeking definitive standards for engagement of the Federal Tribal trust relationship.
Mr. Blackwell was a member of the Chickasaw Nation and was also of Choctaw descent. He was born at Concho Indian Hospital in El Reno, Oklahoma, and was raised in Tishomingo, near the Blue River, and other small towns in the Chickasaw Nation. He spent elementary-age summers with his grandparents who were Bureau of Indian Affairs educators on the North Plains and in New Mexico. Consequently, he had lifelong deep ties with Picuris Pueblo in Northern New Mexico, and with North Plains community institutions, such as the Loneman School on the Oglala Sioux Tribe's Pine Ridge Indian Reservation. He was conversationally fluent in Choctaw, Chickasaw and Lakota, and had a strong affinity for all New Mexico Pueblo communities and Oklahoma Indian Country Tribal customs and traditions.As an educator and lawyer, Ambassador Blackwell was a pioneering advocate for Tribal Nation building, the creation of institutions of Tribal development and governance, and the use of formal modern diplomacy in the nation-to-nation relationship that Tribal Nations share with the United States federal government. He assisted Tribal Nations, privately owned businesses, non-profits and corporations with building solid business relationships.
Mr. Blackwell received his Bachelor of Arts degree in Education in 1964 from East Central State College in Ada, Oklahoma. He was the founding president of the Epsilon Omega chapter of Pi Kappa Alpha fraternity, and the editor of the campus newspaper. Upon graduation, he taught English at Window Rock High School in Ft. Defiance, Arizona, until 1968 when he began his legal studies and received his law degree from the University of New Mexico in 1972. After graduation, he worked at the American Indian Law Center where he served as the Associate Director of the Special Scholarship Program in Law for American Indians. During his tenure, he helped place more than 700 American Indians and Alaskan Natives in law schools all over the United States. From 1974 to 1977, he was the Assistant Dean at the University of New Mexico School of Law.
In 1979, Blackwell established the organization that became the Native Affairs & Development Group, which was relocated to Washington, DC in 1985. As its Director, he served as a consultant nationwide, including as Special Advisor to Chairman Takuro Isoda of Daiwa Securities America in the World Trade Center from 1991 to 1995. He was then among the first American Indians to work in the Wall Street venue, and this work formed the foundation for his insight and ability to guide successful business relationships between private and Tribal business partners.
In 1990, he received his first appointment in diplomatic service for the Chickasaw Nation. He was named the Chickasaw Nation Ambassador to the United States in a 1995 ceremony in Washington, DC. In 1998, Ambassador Blackwell founded Pushmataha House, located on Capitol Hill, which served as an important center for Tribal business, government and cultural affairs. He recently relocated on Capitol Hill to a new Office of the Ambassador, Piomingo House.
As a public servant, Mr. Blackwell's work extended to serving the larger American Indian community in the realms of economic empowerment, health care, education and the environment. He was appointed to the EPA Director's National Clean Air Action Advisory Committee. In 1995, he was selected by the U.S. Secretaries of Commerce, Agriculture, and the Interior to represent Indian Country on the Western Governor's States Drought Coordination Council. He was a dynamic advocate for health care and Indian education. President Clinton appointed him to the Presidential Advisory Council on HIV/AIDS in 1997, where, as the only American Indian appointee, he pushed for awareness and information efforts in Tribal communities. In 2006, he participated in the Indian Country Methamphetamine Task Force, speaking at the National Congress of American Indians Annual Session on how Tribal Nations should campaign to their youth with an innovative method of creating Tribal-specific comic books with an anti-meth theme.
He routinely informed Federal agencies on their trust responsibilities. Speaking on Tribal values in energy needs, he received a Special Act Award from the Secretary of the Department of Energy in 2006. He was a constant voice for Tribal economic empowerment and diversification. He received the National Director's Legacy Award for Lifetime Achievement from the Department of Commerce, Minority Business Development Agency in 2007. Mr. Blackwell was a member of the Native American Bar Association and the American Indian Society of Washington, D.C.
He cherished being a parent and a grandparent to his sons, Geoffrey and Jonathan, and their daughters. He mmensely enjoyed southwestern sunsets, classic style and the storytelling of generations. His laugh will be long remembered.
Mr. Blackwell is survived by his older son, Geoffrey, daughter-in-law, Beth and granddaughters, Megan and Jennifer, of Rockville, Maryland; and his son, Jonathan, daughter-in-law, Jacy and granddaughter, Montana, of Martin's Ferry, Ohio.
A memorial service was held at the National Museum of the American Indian, Smithsonian Institution, in Washington, DC on Saturday, January 26th, the first ever held there for a Tribal leader. Memorial services will be at 11 a.m. Friday, February 22nd, in Ada, Oklahoma, at the Chickasaw Nation Community Center. A memorial service will also be held in Albuquerque, New Mexico.
In lieu of flowers, the family respectfully asks that any donations please be sent in memory of Charles W. Blackwell to the Loneman School, P.O. Box 50, Oglala, SD 57764, on Pine Ridge Indian Reservation.


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Rochester Institute of Technology is one of the top schools to study video game design for 2013, according to new international rankings from The Princeton Review.
RIT's game design and development programs rank fourth at both the undergraduate and graduate levels. RIT's program is housed in the School of Interactive Games and Media within the B. Thomas Golisano College of Computing and Information Sciences.
"Our faculty continue to refine our programs and provide our game design and development students with a world-class educational experience," says Andrew Sears, dean of the B. Thomas Golisano College of Computing and Information Sciences. "This is important and challenging given the rapidly evolving nature of this field and the number of students enrolled in these programs."
The Princeton Review, one of the nation's best known educational services companies, partnered with PC Gamer to produce the "Best Schools for Gaming 2013." The fourth-annual list is published in the April edition of PC Gamer magazine.
To make its selections, The Princeton Review weighed a number of criteria, including school curriculum, faculty, facilities, infrastructure, career services, student scholarships and financial aid.
RIT has been a pioneer in the field of video game design and development education. Gaming students get to work with hands-on research projects like Just Press Play, a game aimed at increasing student engagement and exploration of the collegiate experience. Graduates of RIT's game design and development programs have gone on to work at companies including Microsoft, Electronic Arts, Vicarious Visions and Nickelodeon.
RIT's Bachelor of Science in game design and development provides a broad-based undergraduate education in computing while exposing students to the breadth of game development processes. Students are required to complete coursework in the liberal arts, social sciences and the laboratory sciences.
Students who pursue RIT's master's degree in game design and development take a series of core courses in such areas as emerging technologies, electronic entertainment and history of games. Students can focus on game engine development or artificial intelligence for games while supplementing these studies with courses in a variety of other areas. The degree culminates with a capstone project in which students create their own games.
"Our undergraduate program is one of the largest of its kind," Sears says. "While larger programs are not always better, in this case, the number of students studying game design allows us to offer students a rich variety of relevant courses."
The Princeton Review's rankings for the top 15 undergraduate and graduate schools to study video game design for 2013 are listed below.
Top 15 Undergraduate Schools to Study Video Game Design for 2013
Top 15 Graduate Schools to Study Video Game Design for 2013


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Gay Marriage, Black Voters
Why Obama is able to endorse gay marriage in a way a white Democratic president couldn't.
"I've just concluded that for me personally, it is important for me to go ahead and affirm that I think same-sex couples should be able to get married."
With that statement, President (and candidate) Obama advanced a cause that had been moving at geological speed until Vice President Joe Biden suddenly thrust the administration into support. Last time a presidential campaign jumped the gun on gay matters, Bill Clinton casually promised to end the exclusion of gays from the military in 1992. Although he didn't lose that election, many analysts date the weakening of his administration from his losing battle to make good on that promise, culminating in the universally despised "don't ask, don't tell" policy. Twelve years later, after the Massachusetts Supreme Court issued the first gay marriage decision, African-American boxing promoter Don King toured the black churches of Ohio to gin up the Republican vote. The difference—the black vote went from 10 percent Republican to 17 percent Republican—arguably took the state and the 2004 election from John Kerry.
Obama's committed not to make the same mistake. After Vice President Biden grew feet and walked out of the warm sea on Meet the Press, Obama couldn't duck anymore. But he's not Bill Clinton, and he's not John Kerry. Because he's not white. And so he has a unique opportunity to move the gay issue along faster than anyone else could.
Not so many people still remember, but it was an African-American, then Joint Chiefs of Staff Chairman Colin Powell, who killed Clinton's effort to repeal the exclusion of gays from the military. Before Clinton raised the issue, the exclusion was a matter of Pentagon policy, which the executive could order changed—just as Harry Truman had ordered the military to integrate blacks. Indeed, Truman was the model for Clinton's plans and the gays' hopes. They thought the nation had learned its lesson about racial exclusion and that the heroic example of Truman's early commitment to civil rights would empower Clinton to do the same thing. Those plans and hopes died when the shining star of the integrated military, Colin Powell, the first nonwhite chief of staff in history, denied that racial justice was an argument for gays. "Skin color," the general wrote, "is a benign, non-behavioral characteristic. Sexual orientation is perhaps the most profound of human behavioral characteristics. Comparing the two is a convenient but invalid argument." Repeal might have failed anyway, but once Powell took the stage to deny the racial analogy, it was dead on arrival.
In the two decades after Powell spoke (and before he changed his mind in 2009), the gay revolution, unassisted by any president until this afternoon, undertook the task of changing peoples' minds about the malignancy of their behavioral characteristic. Powell looked more and more like an ungrateful winner who wanted to pull the ladder up once he'd been admitted to the club.
Gays came out, cared for their sick, served with honor, kissed on TV, and started Glee clubs. One small state at a time, they started squirreling away places to marry, until they took New York last June. The New York-centered media covered so many gay marriages, it gave rise to a gay movement to resist the rush to the altar. The latest polling reveals that white people are finally evenly divided on the issue of gay marriage. And nonwhites are similarly split. Liberal commentators use these facts to argue that race is irrelevant. But those numbers are not what matters.
Anti-gay-marriage whites are not voting for Barack Obama. Forty-nine percent of white folks oppose gay marriage, but 74 percent of Republicans oppose gay marriage. And the Republican Party is almost entirely white. Where are the 48 percent of nonwhite voters who oppose gay marriage? Where are almost all nonwhite voters? In the Democratic Party. Even if every single black Republican is anti-gay, there simply aren't enough of them to account for all the black anti-gay voters. Therein lies the danger for a Democratic candidate supporting gay marriage: that voters otherwise disposed to him will not support him because of his stance on gay marriage.
And here is where Obama is different. If the black community doesn't flood the polls, Obama will lose in November. But he's the first black president of the United States. Black voters are sticky with Barack Obama in a way no white president could dream of. For whites, a white president is the natural order of things. For blacks, it was the miracle of Grant Park. Once the Iowa caucus happened, even Hillary Clinton, the wife of the "first black president," could not stem the tide. As black houses went into foreclosure after 2008 and the unemployment rate went through the roof, Obama's support among blacks stayed amazingly firm. As the election approaches, his support is at the same level as in 2008.
A simple thought experiment reveals the issue: Try to imagine Don King in black churches exhorting congregations to vote against Barack Obama over gay marriage. Not going to happen. In this way, the president was uniquely suited among Democratic politicians to advance the issue (just as Powell could have done in 1993). Until today, Obama's mealy-mouthed and harmful public statements on gay marriage looked suspiciously Powell-esque. But as happens now and then to Barack Obama, history gave him an opportunity no one else could seize, and he did.


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in this section
Matthew P. DeLisa
Matthew DeLisa received his B.S. in Chemical Engineering from the University of Connecticut in 1996; his Ph.D. in Chemical Engineering from the University of Maryland in 2001; and did postdoctoral work at the University of Texas-Austin, Department of Chemical Engineering. DeLisa joined the Department of Chemical and Biomolecular Engineering at Cornell University as an assistant professor in 2003. He was promoted to associate professor in 2009 and to professor in 2013, at which time he was named the William L. Lewis Professor of Engineering. He also recently served as a Gastprofessur at the Swiss Federal Institute of Technology (ETH Zürich) in the Institut für Mikrobiologie.
Professor DeLisa's research focuses on understanding and controlling the molecular mechanisms underlying protein biogenesis -- folding and assembly, membrane translocation and post-translational modifications -- in the complex environment of a living cell. His contributions to science and engineering include the invention of numerous commercially important technologies for facilitating the discovery, design and manufacturing of human drugs and seminal discoveries in the areas of cellular protein folding and protein translocation. DeLisa has received several awards for his work including an NSF CAREER award (2005), a NYSTAR Watson Young Investigator award (2004), a Beckman Foundation Young Investigator award (2005), an Office of Naval Research Young Investigator award (2006), and a NYSTAR Distinguished Faculty Award (2007), the inaugural Wiley-Blackwell Biotechnology and Bioengineering Daniel I.C. Wang award (2008), a Cornell Provost's Award for Distinguished Scholarship (2009), the American Chemical Society BIOT division Young Investigator award (2010), and the Biochemical Engineering Journal Young Investigator award (2013). He was also named one of the top 35 young innovators (TR35) by MIT's Technology Review (2005), was selected as the Allan P. Colburn Memorial Lecturer at the University of Delaware (2009), and was chosen to deliver the Keynote Lecture at the SIMB RAFT X Meeting (2013). Most recently, he was named the AIChE Division 15C Plenary Award Lecturer (2013), was selected to the IDA/DARPA Defense Science Study Group (2014-15), and was elected as a fellow of the American Institute for Medical and Biological Engineering (2014).
Research Interests
It has been suggested that life depends on 200-300 core biological processes, the vast majority of which are accomplished by large heterogeneous protein assemblies commonly referred to as machines. Unfortunately, the functional details of many cellular machines have yet to be described for lack of effective tools. In turn, this has hindered our ability to harness nature's machines for tackling problems that cannot be solved with natural systems. The DeLisa laboratory is working to address this need by bridging fundamental biological and chemical concepts with new tools for interrogating and manipulating biological machinery directly in living cells. A major goal of the DeLisa group is to engineer the protein machinery of simple bacteria for solving complex problems in biology and medicine. They focus on the molecular machines of protein biosynthesis as both a target for understanding and reprogramming cellular function and as a toolbox for the creation of therapeutically and industrially relevant molecules. Their unique approach involves probing and exploiting the function and specificity of cellular protein machinery by integrating protein engineering - the science of redesigning natural biomolecular scaffolds - with microbial genetics, biochemistry and molecular biology to address these problems. The end result is a deep understanding of the complexities of intracellular protein machinery that can ultimately be used to inform the engineering of cellular processes for the purpose of discovery, design and production of a diverse array of useful products and processes.
Teaching Interests
DeLisa's contributions to teaching have focused on two concepts. First, to enrich the current chemical engineering curriculum by seamlessly integrating biology as a foundational science of our discipline. Second, to develop group-oriented learning experiences that expose students to engineering design, open-ended problem solving and, whenever possible, hands-on research. Recognition for his past teaching contributions was given by the College of Engineering in 2007 with the awarding of the Mr. & Mrs. Richard F. Tucker '50 Excellence in Teaching Award.
Selected Publications
- 2013. "Ubiquibodies: synthetic E3 ubiquitin ligases endowed with unnatural substrate specificity for targeted protein silencing." Journal of Biological Chemistry. .
- 2012. "Twin-arginine translocase mutations that suppress folding quality control and permit export of misfolded substrate proteins." Proceedings of the National Academy of Sciences of the United States 109 (33): 13392-13397. .
- 2012. "An engineered eukaryotic protein glycosylation pathway in Escherichia coli.." Nature Chemical Biology 8 (5): 434-436. .
- 2010. "Delivery of foreign antigens by engineered outer membrane vesicle vaccines." Proceedings of the National Academy of Sciences of the United States 107 (7): 3099-3104. .
- 2009. "Synthetic metabolic pipelines." Nature Biotechnology 27 (8): 728 - 729. .
Selected Awards and Honors
- CAREER Award (National Science Foundation) 2005
- Biochemical Technology Division Young Investigator Award (American Chemcial Society) 2010
- Young Investigator Award (Biochemical Engineering Journal) 2013
- Defense Science Study Group (DSSG) (IDA/DARPA) 2013
- Elected Fellow (American Institute for Medical and Biological Engineering) 2014
- BS (Chemical Engineering), University of Connecticut, 1996
- MS (Chemical Engineering), University of Maryland, 1999
- Ph D (Chemical Engineering), University of Maryland, 2000
- Postdoctoral Associate (Chemical Engineering), University of Texas, 2001


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In a match of rivals of Shakhtar in the Champions League there was a sensation. The French Lyon has created a sensation in the Champions League, having beaten the defending champion of England of Manc...
Date: a month ago 2018-08-16 13:00 Category: Gaming
The game For Honor is distributed free of charge
For now, from June 12 to June 18, on the official site the game For Honor in the Starter Edition version for the personal computer can be downloaded absolutely free of charge, instead of usual 15 dollars. In this version six heroes, three of whom - initially, and others it is necessary to buy for currency, are available. However, in Ubisoft have already counted that for an unblocking of one character from 8 to 15 hours spent in a game there are enough.
to receive a gift, it is necessary to bring the account to Uplay. And if, yesterday, in day of start of an action, the server experienced big strain and worked unstably, then today necessary actions can be carried out without problems. we Will remind
, For Honor is a game-faytingom, a stimulator of medieval soldiers for personal computers, Play Station 4, Xbox One. An exit of a game was announced at the specialized forum E3 in 2015. There was the first trailer of the video game Cyberpunk 2077 News from the Correspondent.netv of Telegram. Subscribe for our https://t.me/korrespondentnet channel
URL: http://newswell.info/articles/the_game_for_honor_is_distributed_free_of_charge
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The wildlife of Southeast Asia is beautiful and mysterious but under threat. To help raise awareness and conservation funds for selected threatened animals in Southeast Asia, the International Union for Conservation of Nature Species Survival Commission (IUCN SSC) and the European Association of Zoos and Aquaria (EAZA) have teamed up to launch a new campaign.
The EAZA-IUCN SSC Southeast Asia campaign was initiated by EAZA in response to findings from IUCN that large animals (over 1kg) in Southeast Asia are at particular risk of decline and extinction due to illegal trade and habitat loss. The campaign will run until September 2012 and hopes to raise €750,000 for conservation projects to protect a number of different species in Southeast Asia.
Along with raising awareness and funds, the campaign also aims to help reduce the trade and hunting of animals in Southeast Asia, a major threat to many species as they are hunted for food and used in traditional medicines. A fourth aim of the campaign is to influence European consumer behaviour and demonstrate how this can positively benefit biodiversity.
So far there are six projects that the EAZA-IUCN SSC Southeast Asia campaign will support across the Southeast Asia region. Three involve specific species; the Rufous-headed hornbill (Aceros waldeni), the Saola (Pseudoryx nghetinhensis) and the Sumatran Rhino (Dicerorhinos sumatrensis). The remaining three projects support conservation work being done in the Hukaung Valley Wildlife Sanctuary, the Mekong River Basin and the Mesangat Wetland.
Co-chairs of the new campaign are Gary Betton, who works at Banham Zoo and is chair of the EAZA Camel and Camelid Taxonomic Group (TAG) and Will Duckworth who is the IUCN Red List Authority for the IUCN SSC Asian Wild Cattle Specialist Group. Both offer a great wealth of experience and enthusiasm.
You can find out more about the EAZA-IUCN SSC Southeast Asia campaign and the incredible animals it is supporting by visiting the campaign website.
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Justin Bieber Is Obsessed With His Girlfriend Selena Gomez & I Totally Get Why!
Not only did Justin flirt with Selena in front of millions of onlookers at the MuchMusic Video Awards but he even took to his Twitter to compliment her! It's all because Justin's feeling for Selena are the real deal and I'll tell you why!
Justin Bieber can't get enough of Selena Gomez and I must say it's incredibly refreshing. Yes he may only be 17-years-old and they're a young couple by Hollywood standards — Selena is just 18. But I can tell you from experience that if you are head-over-heels in love you want to shout it from the rooftops and tell every single one of your girlfriends! And in this case, Justin telling his over 10 million Twitter fans!
We told you that when Justin took the stage at the 2011 MuchMusic Awards on June 19 that we were shocked by his flirtatious "banter" with Selena. At one point he even called her beautiful and asked her out jokingly on a date. It was unbelievable — and I loved it!
Justin didn't stop there — he even went on Twitter to joke: "@brunomars you def killed it and @selenagomez you did a great job and were lookin good. nice meeting you. lol. ;)"
Justin is so enamored with Selena that he doesn't care what backlash he'll get from his female fans. This to me symbolizes true love. Justin's feelings for Selena isn't just lust — he's been bitten by the Selena bug and he wants us to know.
Ladies, the best thing a guy can do is let you know his true feelings. It rarely happens but when he wants to tell the world you're his — you know he's a keeper.
Justin is in love with Selena and I adore the fact that he wants us all to know!
— Chloe Melas
Get More From Our BFFs at Glamour.com


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BBC News
- Brexit: Labour agrees on 'all options' conference vote
- Contaminated blood scandal: Inquiry 'must uncover truth'
- Women seeking sperm donor online harassed
- Buckingham Palace: Man released over 'Taser' keyring error
- Thomas Jones: Murder arrest over missing student
- Compensation for delay-hit Northern passengers extended
- Labour conference: John McDonnell unveils shares plan for workers
- Child mental health: Camhs 'not fit for purpose'
- Care job vacancies in England rise to 110,000
- Chas and Dave: Dave Peacock pays tribute to bandmate
- Girl with allergy dies after Pret baguette
- Greg James marries partner Bella Mackie
- Contaminated blood scandal inquiry is 'too little, too late'
- The woman reclaiming nude for women of colour
- Corbyn: 'Anti-Semitism is a scourge on any society'
- The Bodyguard: Meet the real-life close protection officer
- Life as a medical photographer at Addenbrooke's Hospital
- Jamie Chadwick races again for first time since historic win
- Labour Conference: Can Jeremy Corbyn keep the party united?
- BBC Breakfast
- Front pages examine Labour Party conference
- The UK's most ambitious children
- Bodyguard reviews: Critics' verdicts on BBC show's finale
- New children's novel brings refugee crisis to the classroom
- Shared ownership: Problems halved or doubled?
- Esports degree: 'I won't spend three years playing games'
- How familial DNA trapped a murderer for the first time
Local Pubs in CAISTER-ON-SEA:
BeerInTheEvening.com search for pubs in CAISTER-ON-SEA
TheGoodPubGuide.co.uk search for pubs in CAISTER-ON-SEA


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A Trial of PEHRG214 in HIV-Infected Patients
|The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
|ClinicalTrials.gov Identifier: NCT00385567
Recruitment Status : Terminated (Difficulty recruiting eligible patients in timely fashion)
First Posted : October 9, 2006
Last Update Posted : August 26, 2010
- Study Details
- Tabular View
- No Results Posted
- Disclaimer
- How to Read a Study Record
HRG2 is a Phase 2 randomized, controlled, open-label, multi-dose trial to determine the efficacy, safety, immunogenicity, and pharmacokinetic profile of PEHRG214 in HIV-infected patients, treated three times weekly for up to 16 weeks.
All patients are receiving optimized standard of care HAART.
The primary objective of the study is to determine the effect of PEHRG214 in decreasing the viral load (>=1.0 log10), as compared to a Control group. The primary hypothesis is that treatment with PEHRG214 will result in clinically meaningful and sustained viral load suppression.
The total sample size is 70-74 patients from approximately 8-10 participating study centers. The first 16-20 patients are enrolled in the non-randomized "pilot arm" and 54 subsequent patients are randomized (2:1 within center) to Treatment or Control group. The total study duration is 7-12 months.
|Condition or disease
|HIV Infections
|Drug: PEHRG214
|Phase 2
The study design is a randomized, controlled, open-label multi-dose trial of PEHRG214 administered intravenously three times weekly, with the potential for dose escalation in selected patients. Patients with HIV infection, viral load at least 10 times greater than the site laboratory's lower limit of detection and CD4 count of <220 cells/mm3, will be entered into the trial. All patients must be taking an optimized background regimen (OBR) of antiretroviral agents, as confirmed by the Principal Investigator, in accordance with the U.S. Department of Health and Human Services Guidelines for the Use of Antiretroviral Agents in HIV-1 Infected Adults and Adolescents, May 4, 2006.
A non-randomized "pilot arm" of 16-20 patients will first receive 2.0 mg/kg three times weekly for 12 doses. After a "pilot arm" patient has received at least 12 doses of PEHRG214 at 2.0 mg/kg, dose escalation to 4.0 mg/kg three times weekly will follow a scheme based on adverse event, HAGAR, and viral load assessments for each individual patient, and in certain cases, further review by the DSMB. After the "pilot arm" patients have received 12 doses at 4.0 mg/kg, all subsequent patients will enter the protocol at the 4.0 mg PEHRG214/kg level. The subsequent 54 patients will be randomized, in 2:1 ratio within center, to the Treatment group and Control group, respectively. The treatment group will receive PEHRG214 at a dose of 4.0 mg/kg three times weekly for up to 48 doses (16 weeks). The Control group will not receive the investigational drug, but will undergo observation while receiving standard of care HAART.
After at least 12 doses of PEHRG214 at 4.0 mg/kg, dose escalation to 8.0 mg/kg three times weekly will follow a scheme based on adverse event, HAGAR, and viral load assessments for each individual patient, and in certain cases, further review by the DSMB.
The Control patients will be evaluated every 4 weeks for 16 weeks according to the Schedule of Assessments in Appendix 1F. After 16 weeks, these patients will have the option of being enrolled in an extension protocol where they can receive PEHRG214.
|Study Type :
|Interventional (Clinical Trial)
|Estimated Enrollment :
|70 participants
|Intervention Model:
|Parallel Assignment
|None (Open Label)
|Primary Purpose:
|Official Title:
|A Phase 2 Randomized, Controlled Trial of PEHRG214 in HIV-Infected Patients
|Study Start Date :
|January 2007
|Actual Primary Completion Date :
|September 2008
|Actual Study Completion Date :
|September 2008
- Decrease in viral load >= 1.0 log10 at 16 weeks
- Positive changes in CD4 count, weight, and Karnofsky Performance Score at 16 weeks
- Improvement in quality of life as determined monthly, using the MOS-HIV Health Survey
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies.
|Ages Eligible for Study:
|18 Years and older (Adult, Older Adult)
|Sexes Eligible for Study:
|Accepts Healthy Volunteers:
Inclusion Criteria:
- Serological documentation of HIV infection at any time prior to study entry.
- CD4 cells count of <220 cells/mm3 within 35 days of study drug administration.
- Viral load at least 10 times greater than the site laboratory's lower limit of detection within 35 days of study drug administration.
- The patient must be taking an optimized background regimen (OBR) of antiretroviral agents, as confirmed by the Principal Investigator, in accordance with the US Department of Health and Human Services Guidelines for the Use of Antiretroviral Agents in HIV-1 Infected Adults and Adolescents, May 4, 2006; (http://www.aidsinfo.nih.gov/guidelines/) or comparable standard of care guidelines.
- OBR has been individually selected for the patient based on prior viral resistance testing and antiretroviral treatment history.
- OBR has been stable for at least 4 weeks prior to Screening and is expected to remain stable for the duration of the trial.
- Karnofsky performance status >=60%.
- Adequate laboratory parameters: absolute neutrophil count >1000 cells/mm3 hemoglobin >9.0 g/dL; platelets >75,000/mm3; creatinine <1.5 x upper limit of normal; SGOT/SGPT <3.0 x upper limit of normal; bilirubin <2.0 mg/dL. Note: Patients who are taking indinavir or atazanavir will be allowed on this trial if their bilirubin is >3.0 mg/dL and if it is deemed by both the Principal Investigator and patient's physician that the elevated bilirubin is solely related to indinavir or atazanavir.
- Women of Child Bearing Potential (WOCBP) must have a negative serum or urine pregnancy test.
- Prophylaxis for Pneumocystis carinii pneumonia using aerosolized pentamidine, trimethoprim/sulfamethoxazole, mepron or dapsone is required for study patients.
- Signed informed consent.
Exclusion Criteria:
- Patient is pregnant or lactating.
- Active opportunistic infection which is progressive, or imminently disabling or life-threatening, in the judgment of the Principal Investigator.
- Cytotoxic chemotherapy, interferon treatment, or radiation therapy within the preceding 3 weeks (patients who have received intralesional chemotherapy will not be excluded, however).
- Any investigational drugs within 30 days or any investigational biologic agents within 6 weeks. Patients taking antiretroviral investigational drugs within Expanded Access Programs (21CFR312.34) are not excluded from participation, provided these drugs are not excluded elsewhere in the protocol.
- Patients who have received an HIV vaccine.
- Known hypersensitivity to animal proteins, including red meats, milk, or milk products, or previous treatment with a caprine antibody and HAGAR (Human anti-goat antibody response) or the presence of HAGAR at screening.
- As this is an experimental regimen, patients will not be permitted to enroll if they had been on an effective antiretroviral regimen, which they tolerated well and which they discontinued for the sake of enrolling in this protocol.
- Active drug abuse.
- Any condition which in the Principal Investigator's opinion may render the patient unable to complete the study or which may pose significant risk to the patient.
- Chronic treatment with immunosuppressant drugs, including corticosteroids, except for the treatment of adrenal insufficiency. Topical steroids are permitted.
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00385567
|United States, California
|L.A. Gay & Lesbian Center
|Los Angeles, California, United States, 90028
|United States, Florida
|University of Miami School of Medicine - AIDS Clinical Research Unit
|Miami, Florida, United States, 33136
|United States, Illinois
|Northstar Healthcare
|Chicago, Illinois, United States, 60657
|United States, Iowa
|University of Iowa - HIV/ AIDS Clinical Trials
|Iowa City, Iowa, United States, 52242
|United States, New York
|Beth Israel Medical Center - AIDS Clinical Trials Unit
|New York, New York, United States, 10003
|United States, Texas
|University of Texas Southwestern Medical Center - HIV Research Clinic
|Dallas, Texas, United States, 75390
|Puerto Rico
|Clinical Research Puerto Rico, Inc
|San Juan, Puerto Rico, 00909
|Responsible Party:
|Simon Wilkinson, Virionyx Corporation Limited
|ClinicalTrials.gov Identifier:
|NCT00385567 History of Changes
|Other Study ID Numbers:
|First Posted:
|October 9, 2006 Key Record Dates
|Last Update Posted:
|August 26, 2010
|Last Verified:
|August 2010
Keywords provided by Virionyx Corporation Limited:
Treatment Experienced
Additional relevant MeSH terms:
HIV Infections
Lentivirus Infections
Retroviridae Infections
RNA Virus Infections
Virus Diseases
Sexually Transmitted Diseases, Viral
Immunologic Deficiency Syndromes
Immune System Diseases


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New York: A new study on the long-term effects of giving away a portion of one`s liver for transplant shows donors can experience physical and psychological complications years after the operation.
Almost half of the 83 liver donors surveyed had complaints ranging from pain and digestive problems to depression three or more years after surgery. But nearly all said they`d donate again, according to the study published in the Annals of Surgery.
"There is a risk for some long-term complaints, which may be potentially controllable by workup modifications, improvements in surgical techniques and a thorough follow-up of donors at the transplant centers," Dr. Georgios Sotiropoulos, lead author and professor of surgery and transplantation at University Hospital Essen in Germany, told Reuters Health in an email.
Prospective donors should be thoroughly informed of possible long-term effects of donation, Sotiropoulos` team wrote in their report, and many of the donors surveyed suggested a central registry of living donors to track how they fared over time.
In a living donor liver transplant, a team of surgeons removes a lobe of the donor`s liver to implant in the recipient. The remaining portion of the donor`s liver regrows to full size within two months.
Transplant surgeons say they would rather not have to put a healthy person at risk by taking a piece of their liver for someone else, but there aren`t enough organs available to provide livers for everyone who needs them.
At the end of October, according to the US Organ Procurement and Transplantation Network, more than 16,000 patients were on the waiting list for a liver transplant -- and nearly 900 patients have died so far this year because no liver became available for them.
The severe shortage and the liver`s unique ability to regenerate itself are why doctors turn to living donors.
Organs from living donors also have some advantages over the alternative, a liver from a cadaver, because a living donor is typically healthier and the donation can occur at the best time for the recipient.
The average age of donors in the German study was 36, and their average time since donating was six years.
In the study, 31 percent of donors complained about having diarrhea or an intolerance to fatty foods. About 10 percent complained of gastroesophageal reflux and a small number of donors had discomfort at the incision site or in the ribs. Three donors reported bouts of severe depression -- two of them requiring hospitalization -- and one patient had worsening of preexisting psoriasis.
Of the 83 donors surveyed, 39 reported no lingering symptoms or problems.
Three young and otherwise healthy men, however, said they had been turned down for life insurance because there`s so little data available on the long-term effects of living liver donation.
Dr. Jean Emond, vice chair of the Department of Surgery and director of the transplant center at New York Presbyterian/Columbia Hospital in New York, said, though the study did not have a control group, its findings are consistent with past research.
"I think the conclusions are cautious and reasonable," said Emond. "We need to keep a close eye on these people."
Emond told Reuters Health that his center aims to bring donors back for checkups once a year.
"A lot of them don`t want to come back because they feel good, because it`s too much trouble or their (recipient) died and they don`t want to be reminded of the bad memories," said Emond. "The other thing is if they live far away it could be hard to do."
He added that there needs to be psychological support before and after the procedure.
"In our center we have a psychiatrist ... to try and understand the makeup that may be exacerbated under the stress of donation," said Emond.
About 4,500 liver donations have been made in the U.S. by living donors since the first surgery in 1989, according to the national transplant database.
The first liver donations from living donors were made to children, who require a smaller piece of the liver than adults.
Emond, who assisted with the first live-donor liver surgery, said the procedure slowly grew in the U.S. until 2001. The following year an infection killed a donor at Mount Sinai Medical Center in New York. According to Emond, the high-profile case led to more stringent regulations for the procedure.
Last year two donors died after the operation, one in Massachusetts and another in Colorado.
"This year was a tough year," said Emond. "Unlike the first two deaths that happened in the U.S., these two deaths happened in centers that have superb safety programs in place. It really shook everybody in the community that`s doing it." But Emond added that doctors cannot expect everyone to survive the risky surgery.
According to Emond, the risk of death after donating a large portion of the liver is about one in 1,000.
"The ethical standard has to be that you do it because it`s the right thing to do for the patient with full and informed consent," said Emond.
Bureau Report


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Gerard Butler: InStyle/Warner Bros. Party Person
Gerard Butler suits up for the InStyle/Warner Bros. Golden Globes Party on Sunday (January 16) at The Beverly Hilton Hotel in Beverly Hills, Calif.
The 41-year-old Scottish actor has been making the rounds at different parties over the past few days.
The night before, Gerry attended The Art of Elysium's 4th Annual Black Tie "Heaven" Charity Gala at L.A.'s California Science Center.
Earlier in the week, Gerard came out to support Save the Children and Artists for Peace and Justice at Bulgari's private event.
FYI: Gerard is wearing head to toe Dolce & Gabbana paired with David Yurman's Sea Urchin Shirt Studs and Cufflinks.


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Salisbury Fire Surround £310.00
Fire Surround Dimensions
Hearth Dimensions
Rebate: 1 inch removable to 3 inches; click here to find out about rebates.
Measurement 'D': This is always from the bottom of the leg to the corner of the opening.
Product Description
Pictured with Black Granite Marble and finished in Olde England White, the majestic Salisbury fire surround adds style and beauty to any living room. Boasting an undeniable presence, the surround is completed with a subtle and yet eye-catching beading around the inside of the legs and on the underside of the shelf. The mantel width is a large 57" and its neutral Olde England White finish suits any marble colour and sits best on standard 54" marble set.
This fire surround can be, made to measure so that it perfectly fits your room, you can also have either Halogen or LED downlights installed for added ambience.
To select a veneered hearth and back panel, use the drop-down menu and add your colour preference at the checkout; alternatively Click Here to select your colour. To view our selection of Hearths and backs, Click Here.
We recommend that you take advantage of our colour sample service as colours on monitors often do not match the finished product. Click Here to have some samples sent to you.
This surround is shown here in Olde England White the Napier Mirror complements this surround perfectly. 'Äã
Range Description
Classic Wood SurroundsThis range of wood mantels showcases a timeless collection of beautiful wooden fireplaces with styles that present a regal aura.
All the surrounds are available in a variety of colour and wood finishes made from high-quality hardwood veneers and the range encompasses durable and functional designs to suit all tastes.
Each mantel is available for any fire application and is individually handmade by expert craftsmen.
Hearth & Back Dimensions
|37" or 40"
|37" or 40"
|48", 54" or 60"
|15" or 18"
Hearth Footprint
We would always suggest that you take delivery of your hearth before cutting your carpet. The sizes given are for the top of your hearth, the footprint is usually around 0.5" on both sides and front.
Bespoke Sizes
We can alter the size of your hearth, in both width and depth. Please call us for a quotation.
Standard Sizes
The standard sizes for hearths are:
|48", 54" or 60"
|15" or 18"
The back panel standard sizes are:
|37" x 37"
|40" x 40"
If your require a hearth that is not an option on your chosen fire surround, please order from our Hearth & Backs section.
All our fire surrounds can be upgraded to be used with an open fires, Solid Fuel Stoves or Gas HE Fires.
You must follow your manufacturers and Hetas guidelines as we do not make the surrounds fire proof. We are ensuring they won't warp or peel if fitted correctly.
You should always ensure that your installer is registered with Hetas, and always ask your installer for identification; they will be able to produce a HETAS ID card with their registration competence on the reverse.
If you do not have an installer then visit the HETAS website (www.hetas.co.uk) and using their search, you will be able to find an installer in your location.
Please call a Hetas engineer for installation advice.
Our surrounds can be used with any gas fire with an output of 4Kw or less. For greater output select the solid fuel upgrade
Gas fires must be fitted per distances from combustible materials, as specified in your instruction manual. Any HE or glass fronted fire must have the solid fuel upgrade. HE & glass fronted fires can only be used with Granite Hearth and Backs.
If you visit www.gassaferegister.co.uk, you will find a list of engineers in your location.
You must use a Gas Safe Engineer if you are having a gas fire fitted, they can generally fit your entire fire surround and will supply you with a safety certificate.
Please call a Gas Safe engineer for installation advice.
All our surrounds can be used with electric fires; you do not need a qualified electrician as they come fitted with standard plugs.
If you are fitting your fire surround against a wall without a hole, then you need to ensure that you have the correct surround rebate. If you have a chimney, this needs a cowel or to be sealed to stop the fire overheating and becoming noisy.
If you are moving a socket, then you need to use a qualified electrician. Once the work has been carried out, you will receive a Part P certificate from the electrician.
If you are looking for a qualified electrician, then a good website to visit is www.electricalsafetyfirst.org.uk.
Call us if you require help with rebates.


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The first reaction when Will Gardner was shown lying dead, blood covering his body from gunshot wounds this season on "The Good Wife" was: "WHAT?" Then came the other: "But Alicia!"
The shocking death of the renegade lawyer, played by Josh Charles, in the season's 15th episode threw fans into a frenzy.
Charles stopped by the Los Angeles Times on Monday to talk about the show's reenergized fifth season, which critics have lauded. Among the topics discussed, the push-and-pull dynamic between Will and protagonist Alicia Florrick (Julianna Margulies) — a central component to the show.
The season had largely been propelled by the former lovers being at odds after Will discovered Alicia, whom he brought into his law firm when no one wanted her, sneaking around to start her own firm.
The tension between the eternal flames was high throughout the season — and the two hadn't yet fully called a "truce" when Alicia received the heart-stopping call from Kalinda that Will had been killed. Asked about his thoughts on how things ended for Will and Alicia, Charles said the untidiness felt appropriate.
"I think that's part of the intent," he said. "You kind of see the ice thaw a little bit and so maybe you get a hint that things could one day improve. And then they don't. The rug gets pulled out from under you. That happens in life, I think. I don't know. I was always drawn — maybe it's the dark part of my personality — to the tragic element of their relationship. Because we've seen the other stuff done a lot. And I think the idea of two people who really do feel a connection, but for all these different reasons [their timing] is off — I always responded to that element."
Charles added that he never discussed with creators Robert and Michelle King what they thought their end game was for those two characters. But he has his own thoughts on it.
"My feeling, my own opinion, is that I don't know that it ever was the end game," he said. "I think there was always going to be something between them, a connection. I felt like the ending — you got a sense, I think from that episode, that they were going to find a mutual respect again. It was going to happen. Because, like I said, with time and distance and healing, Will could sort of take his emotions out of it. He could look at the move and go, 'You know what, maybe I would have done something similar.'"
For more on what Charles had to say about his time on the show, check out the video above.