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Call 24/7.
Here are the best methadone clinics in Detroit Lakes, MN. Get immediate methadone treatment in Detroit Lakes from a local and trusted Methadone clinic. Find medication-assisted treatment options in Detroit Lakes, Minnesota from one of the treatment centers below.
Call (877) 855-0765 for 24/7 help with treatment.
Compassion House is a methadone clinic in Detroit Lakes, MN. It is situated in Becker County at 811 8th Street Se, 56501 zip. Compassion House provides short-term residential treatment, long-term residential treatment and full residential treatment. Other than methadone treatment, Compassion House offers HIV and AIDS education, support and counseling, substance use education and hepatitis education, counseling and support. Compassion House provides medication assisted services to men.
24/7 help with treatment
Drake Counseling Services is a methadone treatment facility in Detroit Lakes, Minnesota. It is located in Becker County at 28579 Highway 10 East, 56501 zip. Drake Counseling Services provides regular outpatient treatment, intensive outpatient treatment and outpatient treatment. Other than methadone treatment, Drake Counseling Services offers substance use education, individual counseling and group counseling. Drake Counseling Services provides medication-assisted services to women and men.
24/7 help with treatment
Lakes Counseling Center is a methadone clinic in Detroit Lakes, MN. It is located in Becker County at 1000 8th Street Se, 56501 zip. Lakes Counseling Center provides regular outpatient treatment, intensive outpatient treatment and outpatient treatment. Other than methadone treatment, Lakes Counseling Center offers family counseling, substance use education and individual counseling. Lakes Counseling Center provides medication-assisted services to women and men.
24/7 help with treatment
Treatment at a suboxone clinic in Detroit Lakes is often similar to the treatment received at a methadone clinic. Both of the medication assisted treatment options work by reducing narcotic and opioid cravings for those who are addicted. A big difference between suboxone and methadone is that suboxone can be prescribed by doctors, while methadone treatment needs to be received at a clinic.
Services such as intervention, counseling, relapse prevention, behavior therapy and other support services are commonly found in methadone clinics throughout Minnesota. A methadone clinic may be part of a larger addiction treatment center, and as such, may have all of the services found in Detroit Lakes drug rehabs.
Each methadone clinic in Detroit Lakes has its own policy about what patients they will take. However, most clinics will accept both walk-ins and those who have made a previous appointment. It is usually a good idea to call ahead of time just to confirm availability.
The short answer is no. Methadone treatment services in Detroit Lakes are available both in residential format, also known as inpatient, as well as outpatient format. Having both options allows addicted individuals to choose whether inpatient or outpatient clinical treatment will work better for their lifestyle.
There are a total of 3 medication assisted therapies that can be received in Detroit Lakes: methadone, buprenorphine (Suboxone) and Naltrexone. All three are approved by the FDA for drug addiction treatment. Methadone is the one that is most commonly used in addiction clinics.


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Drake's highly anticipated Certified Lover Boy album has yet to be released, but we've finally got a better look at the merch.
Drizzy's been obsessed with California-based brand Chome Hearts for the better part of the last year and has been flexing exclusive pieces like the hoodie and cross-embossed seats in the video for "What's Next." Now, the partnership between OVO and Chrome Hearts is giving us a sneak peek at some merchandise that hopefully will be available to the public.
The first OVO member to flex a few pieces was none other than Chubbs, who previews them on his Instagram. Pictured are matching sweatpants and sweatshirts that feature Chrome Hearts' massive cross on the back with an Old English font. Then, down the leg, it reads "Certified Chrome," an apparent not to the 6 God's upcoming album. The colors range from navy with yellow detailing, red with white detailing, tan with red detailing, and a colorful sky blue with yellow detailing.
Chubbs even posted a short clip of him donning the tan pants, which gave us another sneak peek at the upcoming all-white NOCTA x Nike Hot Step Air Terra, which looks like a slightly modern take on the Air Terra Humara.
It wasn't long after that the OVO boss himself took to Instagram for another hint at what could be coming from the OVO x Chrome Hearts link up. In his stories, he posted a picture of OVO co-founder and co-manager Oliver El-Khatib rocking the navy sweats, with a matching yellow Lamborghini truck in the background, no less.
The collaboration is no surprise, given that Drake even has some jewelry from Chome Hearts, which is the company's original foray. Nearly a year ago, while riding around Toronto, he showed off a diamond-encrusted gold Rolex with a chunky link bracelet and tagged Chrome Hearts.
While it would be nice for the merch to see a general release, we're still waiting for the album, Drizzy.

subset: commoncrawl


text: Cullen Lilley (Biology / Music, '17) is employed as a Microbiologist at the Centers for Disease Control and Prevention (CDC). In this role, Cullen applies next generation technologies to diagnose and subtype bacteria for the National Listeria, Yersinia, Vibrio, and Enterobacteriaceae Reference Laboratories. Cullen will also be pursuing a Master's Degree in microbiology to prepare himself for a career in clinical microbiology and infectious disease. Prior to this position, Cullen worked for one year as a Microbiology Technician in an industrial microbiology laboratory at WuXi AppTec. During his time there, he learned how modern diagnostic molecular microbiology is conducted and achieved the title of molecular diagnostic technologist with the American Association of Bioanalysts—MDxT(AAB). Cullen is happy to share his experiences with interested students.


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The Trump administration has issued a stop-work order on an independent study that was attempting to study safety on offshore drilling to make the process safer.
The National Academies of Sciences, Engineering and Medicine (NASEM) was ordered by the Interior Department's Bureau of Safety and environmental Enforcement (BSEE) to halt its study earlier this month.
The study was supposed to review and update BSEE's offshore oil and gas operations inspection program to enhance safety, which was established after the 2010 Deepwater Horizon explosion that killed 11 people. Last year, the BSEE was heavily criticized for "[continuing] to rely on pre-Deepwater Horizon incident policies and procedures."
A final decision on canceling the contract will be made within 90 days. In the meantime the BSEE is "paused…to allow time to ensure that there are no duplicate efforts."
As Jacqueline Savitz, a vice president with the environmental group Oceana, stated to The Time-Picayune, "One thing we should all be able to agree on is that safety is of paramount importance, so preventing a study like this simply flies in the face of common sense."
This is the second time in the last four months that the Interior Department has cut off funds to the National Academies for a safety study. In August, funding was cut from the Office of Surface Mining for research on the health effects of people in Appalachia living near mining operations.
The Sierra Club believes that the move was to allow for a major push to expand offshore drilling. "I think this is an example of Trump demonstrating he wants to open up federal waters to more drilling at the expense of people on the planet. He is much more supportive of corporate polluters than protecting people's safety," says Kelly Martin, deputy director of the Sierra Club's Out Wild America campaign.
NASEM issued the following statement regarding the decision:
"The U.S. Department of the Interior's Bureau of Safety and Environmental Enforcement has ordered the National Academies of Sciences, Engineering, and Medicine to suspend all work on a study to review and update the bureau's offshore oil and gas operations inspection program to enhance safety. The stop-work order, dated Dec. 7, says that within 90 days the stop-work order will either be lifted and work on the study can resume, or the contract to perform the study will be terminated. The committee conducting the study held its first and only meeting (to date) in Washington, D.C. on Oct. 26-27. Future meetings planned to be held in the Gulf of Mexico region have been put on hold. The National Academies are grateful to the committee members for their service and disappointed that their important study has been stopped.
This is the second National Academies study halted by DOI in the last four months. In August, a study on the potential health effects for people living near surface coal mining sites in Central Appalachia was stopped pending a review of contracts by DOI. The National Academies have not received any update on the status of that review and the study remains on hold. Given how important this study is to the citizens and communities surrounding these surface mining sites in Appalachia, the National Academies believe the study should be completed and are exploring options to do so. Some private donors have expressed an interest in funding the completion of the study.
The National Academies of Sciences, Engineering, and Medicine are private, nonprofit institutions that provide independent, objective analysis and advice to the nation to solve complex problems and inform public policy decisions related to science, technology, and medicine. They operate under an 1863 congressional charter to the National Academy of Sciences, signed by President Lincoln."


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220 VOLTS Domo DO970T 4-SLICE TOASTER features Electronic toast control, Rotary browning control and Integrated bun warmer.
Product Code: Domo DO970T Product ID: 15025
Product sold by: samstores.com
4 Long-slice
Electronic toast control
Rotary browning control
Defrost & reheat function with LED indicator.
Cancel button.
Integrated bun warmer
Slide out crumb tray.
Cable storage
Color: Brushed steel.
This appliance is not designed for use in
Name | Rating | Comments |


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In late September, Foundation debuted on Apple TV+, bringing Isaac Asimov's sci-fi franchise to the screen for the first time. "The series of books was long held to be unfilmable," the BBC said.
Less than a month later, Dune arrived on HBO Max and in domestic multiplexes, having hit international theaters weeks before. The movie marked the first attempt in more than 20 years to translate Frank Herbert's books to the screen, after multiple prior tries that resulted in an unforgettable flop of a film and two forgettable TV miniseries. "Dune has earned a reputation for being 'unfilmable,'" Time observed.
The month after that, The Wheel of Time rolled out on Amazon Prime Video. Like Foundation, the series represented the inaugural big- or small-screen adaptation of a seminal genre text—in this case, Robert Jordan's library-length opus. "The Wheel of Time is the ultimate unfilmable fantasy saga," NBC News noted.
In less than two months, three of the most notoriously unadaptable pieces of popular fiction from the second half of the 20th century yielded three honest-to-goodness, full-fledged adaptations. Almost in tandem, Foundation, Dune, and The Wheel of Time shed their "unfilmable" labels not only on tautological grounds—they had, in fact, been filmed—but based on some amount of merit. All three were, at minimum, well cast, competently (and expensively) produced, and coherently told; all three met with more critical acclaim than condemnation; all three earned green lights for sequel seasons or films. Their nearly simultaneous and at least semi-successful releases reflected the culmination of multiple trends in on-screen, scripted entertainment that made it both desirable to tackle these Everests of IP and artistically and financially feasible to summit them. Together, they made 2021 the end of "unfilmable."
The reasons for the former widespread belief in the three properties' unsuitability for the screen vary by the franchise, but in all three cases, the difficulties begin with the extent of the source material and the scale of its world building. The Wheel of Time is a 14-book (plus a prequel) series so sprawling that it took two authors to finish it; Jordan died before he could complete the narrative, leaving Brandon Sanderson to pen the last three volumes based on Jordan's notes. All told, the story spans a five-figure page count and close to 4.5 million words.
Foundation began as a series of short stories that were collected into a trilogy; decades later, Asimov added two prequels and two sequels, resulting in a seven-book series with enough peripherally related novels in their orbit to form a 15-book suggested syllabus. Dune comprises six novels, not counting the two sequels published by Frank's son Brian and Kevin J. Anderson, who finished the story the elder Herbert had planned to tie up in a seventh book he hadn't begun when he died. In case the saga wasn't convoluted enough, the younger Herbert and Anderson also pumped out 14 more prequels (and counting).
The three epic tales take place in far-future versions of our current reality—so distant in time and/or place that only scattered references to the world we know survive. In place of our historical-cultural context are thousands of years' worth of backstory stuffed with cycles of rapid progress and complete collapse; fearsome devils and feuding dynasties; inscrutable prophecies and struggles to control interstellar travel; complex systems of magic and science so sophisticated that it's indistinguishable from magic; mysterious sisterhoods or few female characters at all. As Tayshia Adams would say, "It's a lot." For those inclined to immerse themselves in stacks of lore-filled doorstops, Foundation, Dune, and The Wheel of Time are rare treasures. But for producers and screenwriters in search of stories that could be compressed into two-hour movies or hour-long episodes with manageable budgets, they were tantalizing, unobtainable totems of nerd culture whose hordes of fans and enduring renown didn't translate into lucrative cinematic or televised tentpoles.
Thus, the trifecta of unfilmability remained on networks' and studios' radars but took decades to creep from "optioned" to "developed" to "produced." After the fallout from David Lynch's infamous 1984 take on the material, Dune went without another movie version for almost 40 years, though Syfy aired two three-part miniseries, Frank Herbert's Dune and Frank Herbert's Children of Dune, in 2000 and 2003, respectively. (Herbert's books also spawned 2013's Jodorowsky's Dune, a celebrated documentary about an earlier, doomed adaptation attempt.) Five years elapsed between the 2016 announcement and 2021 release of the version that eventually clicked, which was produced by Legendary, directed by Denis Villeneuve, and distributed by Warner Bros. That effort followed a four-year Paramount project that never came to fruition.
At least there was some precedent, however derided, for a Dune adaptation. Foundation went through roughly five false starts—mostly film projects, plus a planned HBO series—over a quarter-century or so before its big breakthrough this year as an Apple streaming series, created by Josh Friedman and showrunner David S. Goyer, whose 10-episode first season most famously featured Jared Harris and Lee Pace. And various would-be creators whiffed on Wheel of Time miniseries, film, and TV adaptation attempts over 20-plus years before another series slowly came together in an eight-episode first season coproduced by Amazon Studios and Sony Pictures Television, run by Rafe Judkins, and headlined by Rosamund Pike.
Given the investments of time and resources required to propel these properties to the screen, it was, perhaps, preordained that the massive swings wouldn't be one-offs. Mercifully for fans who had dreamed of these adaptations for decades, more Dune, Foundation, and The Wheel of Time are on the way. Despite the pandemic and a day-and-date cinematic/streaming release, Dune has grossed almost $400 million in theaters worldwide, and according to some sources it was the most-watched streaming movie for weeks after its high-profile launch. All in all, the movie did brisk enough business to seal an unsurprising announcement of Dune: Part Two, which is scheduled for October 2023. (Villeneuve hopes to make at least three Dune movies, and a prequel streaming series, Dune: The Sisterhood, is also in the works from a separate creative team.) Streaming audience sizes being as opaque as they are, it's tough to tell how well watched Foundation and The Wheel of Time have been, but both were renewed for second seasons before their first seasons premiered, and The Wheel of Time especially seems to be something of a hit.
It's not a coincidence that this wave of once-unfilmable adaptations crested in 2021. As the streaming wars have intensified, Hollywood's appetite for TV content has grown as insatiable as a sandworm. This year, the industry set another new record for scripted-TV quantity, the product of a pandemic-induced production backlog that caused a slight release downturn in 2020, a COVID-caused uptick in demand for at-home entertainment, the launch of even more streaming services, and increased competition among the existing streaming top dogs amid slowing subscription growth. Those forces have fueled bigger budgets, higher-pedigree casts and creators, more flexible formats, and greater tolerance for risk in the fight for differentiators—prestigious, must-see series with the potential to drive subscription growth. Those series tend to be drawn disproportionately from fantasy and sci-fi, which—as Game of Thrones most powerfully demonstrated—bring built-in fan bases and long-gestating stories that are ripe for the picking. (Unless their world-builders unexpectedly slow down.)
An annual avalanche of reboots, sequels, and spinoffs isn't sufficient to meet the demand; stocking streaming catalogs takes fresh adaptations, too. Enter the unfilmables. After decades of neglecting and mismanaging video game IP, Hollywood has gotten wise to gaming's largely untapped stockpile of stories: HBO's The Last of Us, Amazon's Mass Effect, Paramount's Halo, and Sony Pictures' long-delayed Uncharted movie (with a screenplay by Judkins) are among the forthcoming big bets on the genre. But beloved, bestselling book series that haven't been seen on screen (lately, at least) also broadcast the siren song of recognizable names, preexisting demand, and near-infinite narrative runways. Foundation, Dune, and The Wheel of Time may have been famously unfilmable, but at least they were famous for something.
Other "unfilmable" properties have been filmed to great effect: Stanley Kubrick supposedly dismissed The Lord of the Rings as unfilmable decades before Peter Jackson leveraged more advanced technology to bring it to the big screen. In the past, though, only moviemakers had pockets deep enough to bankroll convincing sci-fi/fantasy special-effects fests, and they would have had a hard time condensing the likes of Foundation down to two hours—or even LotR's nine. The explosion in scripted budgets and the increasing quality of home theaters now allows TV writers, producers, and directors the luxury of presenting an extended sci-fi/fantasy narrative (or an eight-hour docuseries about the Beatles) without sacrificing the audiovisual spectacle that comes from a big screen and surround sound. Foundation, Dune, and The Wheel of Time are big. It's the pictures that got less small.
Foundation and Dune debuted on streaming services that launched in late 2019 and mid-2020, respectively, and that made significant strides this year in their quests for award wins and market share. The Wheel of Time is a cornerstone of Amazon's strategy of investing more money in major originals to lure eyeballs away from leading rivals Netflix and Disney+ (which boast buzzy exclusives of their own). If you're going to drop half a billion bucks on a Lord of the Rings prequel, why not double down and snap up a Tolkien-inspired series whose first book hews uncomfortably close to Fellowship's framework? Splashy superhero, sci-fi, and fantasy shows can cut through the static of Peak TV: Amazon boasts The Boys; Netflix nabbed The Witcher, Squid Game, and Shadow and Bone; and Disney never stops its MCU and Star Wars assembly lines. The showrunners of Foundation and The Wheel of Time envision their adaptations as eight-season series, best-case outcomes that remain many renewals away but give the streaming execs who hold their rights something to salivate over.
The path to these three challenging adaptations was smoothed by the success of another series that (sadly) ran for eight seasons: Game of Thrones. George R.R. Martin's A Song of Ice and Fire—another fantasy series once said to be unfilmable, thanks to its depth, its breadth, and its surplus of point-of-view characters—yielded one of the biggest (era-adjusted) TV hits of all time. Thrones became all-consuming because of a confluence of factors, including an active online community that predated the adaptation, suspense surrounding the (still)-unknown ending of the book series, and its pre-Peak TV debut. But A Song of Ice and Fire also oozed attributes that, despite its unfilmable label, made it a great fit for TV: subversive, stunning twists, compelling characters, and a heaping helping of sex and violence. For all of their virtues, Foundation, Dune, and The Wheel of Time individually lack some or most of those qualities—which, when combined with an even less favorable media environment for a monoculture-caliber smash, makes Amazon's once-explicit goal of finding the next Game of Thrones seem far-fetched.
It's easy to be cynical about the economic imperatives underpinning the emergence of these heretofore unfilmable franchises, and one could decry the lack of Hollywood hero's journeys that haven't been heard before. (As if there were ever a time in human history when our species didn't recycle stories.) These adaptations were developed against a backdrop of other tiring trends: Actual and fictional conglomerates alike are acquiring and consolidating content catalogs, the better to brew up a postmodern mélange of callbacks, crossovers, and nostalgia. Just as investors demand exponential growth from companies in more traditional industries, investors in studios demand IP proliferation. Fictional galaxies aren't good enough; only universes or multiverses suffice. Characters connected by little more than a shared corporate parent are meeting up in proto-Metaverses or kicking each other's butts in a rash of Super Smash Bros.–style brawlers. Some of the Frankenstein's monsters that stem from this thirst for synergy are exciting (Free Guy), and some are deflating (Space Jam: A New Legacy); at times, a single franchise swings between the two poles. In the aggregate, though, the constant bombardment by brand names feels overwhelming either way.
From the audience's end, the fact that a piece of IP can be filmed today doesn't necessarily suggest that it should be filmed. There's a hefty opportunity cost to developing any big-budget show, and placing a big bet on a Foundation or a Wheel of Time may preclude the pursuit of several smaller-scale projects whose ambitions don't depend as much on green screens. On the other hand, Dune, Foundation, and The Wheel of Time—in that descending order—are all genuinely enjoyable to varying degrees.
If there's a common element to the three adaptations' defiance of those dire, "unfilmable" forecasts, it's their willingness to make judicious departures from the books. Villeneuve reduces Dune's lore to its essence, stripping out some of the visions and complex plot elements that Lynch labored to preserve. Foundation simplifies Asimov's millennia-spanning, anthology-series structure, using technological tricks and a clever reimagining of the empire's rulers to keep the cast consistent throughout. The Wheel of Time abridges Book 1's travelogue elements, conflating certain cities and sequences to accelerate the lengthy trip from the Two Rivers to Tar Valon. There's also much more sex in TV Foundation and The Wheel of Time than there was in the books that inspired their first seasons. (Actually, any amount of sex would qualify as much more sex than that.) And all three adaptations diversify their casts, rejecting the predominantly white worlds of old-school sci-fi/fantasy.
The adaptations' omissions come at some cost. Even with a 155-minute running time, Dune surrenders some of the series' philosophical musings and monologues, nodding at its themes instead of exploring them explicitly. The main knock against the film is that it doesn't come close to finishing the first book's story, a deficiency its sequel(s) should address. Foundation is faithful to Asimov's themes but plays fast and loose with some science and tries a tad too hard to inject romance into a story that was largely devoid of it. (Then again, it helps to have compelling characters, and as originally written, Foundation doesn't.) If anything, The Wheel of Time (which will wrap up its season on Friday) is excessively sped up, losing a little character development in its efforts to keep the exposition and set pieces coming. The on-screen series spells its stakes out too plainly: If the book has a will-they-or-won't-they, the show almost immediately makes clear that they will. And while the book initially keeps the reader in the dark about the core characters' roles, the show shares revealing prophecies from the start. As a recent reader of the start of the series, I found some of the Amazon version's subtle and seemingly arbitrary tweaks distracting.
Across the board, the adaptations are more action-oriented, more sanded down (no Arrakis pun intended), and more accessible than the books, which can be a mixed blessing. But although not every subplot, character, or personality trait makes the cut, the creative teams largely wield their scalpels responsibly: If we're grading on an adaptation difficulty curve, they graduate with honors. Plus, a large part of the appeal of an adaptation is the chance to see what an imaginary world might look like outside of one's mind's eye. The Foundation and Dune adaptations are worthwhile if only because they look incredible. (By contrast, Wheel of Time's CGI and even practical effects in some scenes are almost embarrassingly bad; maybe Amazon can toss some of LotR's loose change Wheel's way next season.)
Some critics of the Foundation and Dune adaptations argue that the old Foundation and Dune still haven't been filmed—that what we got instead are altered imitations masquerading as the originals. There's some truth to that, as there is with any adaptation—cue the age-old movie vs. book debate—but if any adaptation should get to take creative license, it's one that tackles a book as inherently hard to film as Foundation or Dune. Plus, there's something to be said for switching things up to a certain extent. As a partly plot-driven viewer who's perpetually swamped with scripted TV, I've found myself feeling less and less amped about adaptations, especially those that largely retrace the steps of source material I've already read (or played). In general, I'd rather opt into an adaptation that uses the source as a springboard to tell a fresh story set inside the same universe, like Arcane vis-à-vis League of Legends, despite the problems with prequels. Change can be scary, but the unaltered books will still be there when we want them.
If Foundation characters became studio executives, Salvor Hardin might declare adaptations the last refuge of the incompetent. But execs can't consult Hari Seldon when projecting TV ratings or box office earnings. Instead, they default to known names, which means more adaptations and offshoots of other shows. But with almost 2,000 scripted series airing per year, there's more than enough room in the TV tent for both originals and retreads. In the 2020s, TV truly can be anything, from the offbeat specificity of Evil or Reservation Dogs to the IP powerhouses that are vying to claim a portion of Thrones' audience, like the Diadochi carving up the empire of Alexander the Great.
With more streamers stockpiling originals and Foundation, Dune, The Wheel of Time, and other credible recent adaptations (such as The Stand and His Dark Materials) proving that development hell is escapable, the genre vault could be about to cough up more film and TV holdouts. The Three-Body Problem is headed for Netflix, and—speaking of series that have proved hard to adapt—Villeneuve is attached to direct Rendezvous With Rama. (I know I said I was sort of over adaptations, but that one makes me drool.) Might The Dark Tower finally make it to TV? Could Amazon set its sights on fully fleshing out any deep Tolkien lore still left on the vine? What about The Kingkiller Chronicle, which seems to be on the backburner after seeming several years ago to be the next big thing? Or Discworld, which makes Wheel look like light reading? The Wheel weaves as the Wheel wills, but if those series (or others) aren't part of the Pattern, it won't be because they're unfilmable. That idea died this year.


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Combination Padlock, 1-7/8in, Assorted Colors
The Master Lock No. 1561DAST Standard Dial Combination Padlock features a 1-7/8in (48mm) wide metal body for durability, with an anodized aluminum finish. The 9/32in (7mm) diameter shackle is 3/4in (19mm) long and made of hardened steel, offering extra resistance to cutting and sawing. The 3-digit combination offers keyless convenience. The locking mechanism features anti-shim technology, offering maximum security. The bright metallic colors simplify locker identification. The Limited Lifetime Warranty provides peace of mind from a brand you can trust.
- Bright metallic color simplifies locker identification
- 1-7/8in (48mm) Wide durable metal body with anodized aluminum cover
- Hardened steel shackle for extra cut resistance
- 3-digit combination security for keyless convenience


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Our aim is to study the effect of different temperatures and pH on the activity of salivary content, amylase on starch.
All living beings need energy to survive. It is from the food we consume that we get our energy. We know that the energy we are getting is by the process of digestion that breaks down the complex substance of starch into simpler molecules of glucose, which are further metabolized into CO2 and water through the process of glycolysis. The human digestive tract starts at the mouth and ends at the anus.
The digestion of the food starts as soon as we put food in our mouth. Our teeth cut the food into small pieces and the salivary glands secrete saliva that mixes with these food materials. The saliva contains an enzyme called salivary amylase which hydrolyses starch into maltose. The complete digestion of starch occurs only in the small intestine by the action of pancreatic amylase.
The activity of enzymes is strongly affected by several factors, such as temperature and pH.
All enzymes are proteinaceous in nature. At a lower temperature, the enzyme salivary amylase is deactivated and at the higher temperature, the enzyme is denaturated. Therefore, more time will be taken by an enzyme to digest the starch at lower and higher temperatures. Optimum temperature for the enzymatic activity of salivary amylase ranges from 32 °C to 37 °C. The optimum temperature means that the temperature at which the enzyme shows the maximum activity. At this optimum temperature, the enzyme is most active and hence, takes less time to digest the starch.
The optimum pH for the enzymatic activity of salivary amylase ranges from 6 to 7. Above and below this range, the reaction rate reduces as enzymes get denaturated. The enzyme salivary amylase is most active at pH 6.8. Our stomach has high level of acidity which causes the salivary amylase to denature and change its shape. So the salivary amylase does not function once it enters the stomach.
The effect of temperature and pH on the activity of salivary amylase on starch can be studied by using the Iodine test. If we add saliva on starch, the salivary amylase present in saliva gradually acts on starch and converts it into maltose. Starch keeps on giving blue colour with iodine till it is completely digested into maltose. At this point, no blue colour is formed. This is the end point or achromic point.


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Many businesses were surprised by how difficult it is to sell products over the Internet. Admittedly, you'd have to pay people to cart away some products, and people sometimes just browse the Web to confirm that they're getting a bargain at local stores. But some otherwise sensible businesses neglected a key rule: the more difficult you make it to buy your products, the fewer you'll sell.
Jared Spool, founder of User Interface Engineering (www.uie.com), has devoted considerable effort to understanding how people use – and fail to use – the Web. Recently, he described how each step in the purchasing process discourages some potential buyers, eliminating them the same way the mesh of a sieve prevents large grains of sand from passing through.
You begin losing customers when they reach your home page and can't find what they're looking for. If that product doesn't immediately appear on the screen, and they don't know its name, some try out links to different parts of your site until they find one that leads to the product.
If they know the name, they may instead try the search function and hope they spell the name correctly. Unfortunately, frequent Web users know how unintuitive many links are, and how frustrating search engines can be. Many customers quit after following links deep into your site without finding what they seek or search until they exhaust all possible spellings. Sometimes they alternate between these approaches.
Both obstacles can be overcome if you study the words visitors actually use to describe their needs. Search engines and links fail when your Web pages use only the words you chose; with no synonyms, anyone who relies on words you didn't include in your site won't find what they seek. The solution? Hire a professional indexer who understands how people use words to create a traditional "back of the book" index for your site or to help you choose keywords.
More customers disappear after they find a product – and an array of alternatives. Even those who know they can display each product in its own browser window find that alternating among all these open windows gets frustrating, and either print the pages or try to memorize the differences between the products.
Few sites support the most common shopping behaviour: displaying products side by side for easy comparison. Assuming you actually permit such comparisons, you may eliminate more customers by failing to provide the information they need to make a decision, or providing useless information. To know what criteria people use to compare products, you'll have to ask them.
Those who decide to buy, however, face another obstacle when they reach your online cash register and discover it takes longer to fill in pages of personal information than to shut down the computer and visit the local mall. You could solve this problem by convincing buyers to set up an account so future purchases take relatively few keystrokes, but only repeat customers will be motivated to do so.
Concealed shipping charges also sabotage many sales; displaying these charges on the same page as the product, or linking to a shipping cost calculator that opens in its own window, might prevent this. Those with the tenacity to actually complete an order often receive the wrong model, colour or size. Understanding what buyers expect to receive, and how to ensure that they get it, solves this problem; failing to do so leads to product returns, lost sales and perhaps even lost customers.
In one study, Spool found that only 34 of an original 100 eager buyers successfully obtained the product they sought. How these statistics compare with those for traditional stores is a matter for another study. Here, the important point is that each part of the sieve can be understood and eliminated or minimized – but only if you're willing to act as a user's advocate by identifying the obstacles and proposing solutions. I'll discuss a few more details in the next article.
Hart ([email protected]) is a translator, technical writer, editor and a senior member of the Society for Technical Communication. He lives in Pointe-Claire, Que., where he works for a forestry research institute


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Horoscopes by Rob Brezsny
Week of September 14th, 2006
(December 22-January 19)
When playing the card game known as bridge, you're fortunate if you're dealt no cards of any particular suit. It allows you to use the trump suit to win tricks. There's an analogous situation in your life right now, Capricorn. A lack of a certain resource can work to your advantage. It will allow you to be a free agent, an X-factor, a wild card. You'll be able to capitalize on loopholes that aren't normally available to you. Luck will come to you through what you're missing.
Need a few more whacks applied to your mental blocks in the coming week? A few more caresses administered to your growing edge? Cruise on over to your Expanded Audio Horoscope for the week ahead.
Thousands of things go right for you every day, beginning the moment you wake up. The vast majority of everything is working with breathtaking efficiency and consistency. You would clearly be deluded to imagine that life is primarily an ordeal.
The preceding oracle comes from my book, PRONOIA Is the Antidote for Paranoia: How the Whole World Is Conspiring to Shower You with Blessings. It's available at Barnes & Noble and Amazon.


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What we can realistically expect is not cast in stone. It's a creation—a result of the way we think and act. If we treat people badly, it's realistic to expect they won't like us. If we treat them well, we earn their loyalty, cooperation, and love. Always, we are potters working with the clay of this world.
George: George has two friends: one expects the best of him, the other expects the worst. They bring out two different Georges. What kind of George would you bring out? It would depend on your approach, don't you think?
Realism and relationship. Statistically, over 50% of marriages end in divorce. What that means is, over 50% of people fail to meet the requirements for enduring, fulfill- ing love. But if you want to know what your chances are, it depends on what you do, and the heart you do it with.
Man #1: He loves his wife generously, he cares to understand her, and in practical matters he's responsible and supportive. HIS chances for lasting love are very high.
Man #2: He is generous in financial terms, but emotionally inattentive and dismissive. For HIM, it would be UNrealistic to expect success in love.
What generalizations can be made about love, then? None! It is realistic to expect love to fail if you create conditions in which it must fail—with selfishness, reactivity, insensitivity, etc. But if you offer consistent love and care, and choose a genuinely loving partner, you have reason to expect beautiful results—realistically.
Realism and past experience. Most people think it's realistic to expect the past to repeat itself. But is it? Only if your approach stays the same. If your approach changes, things will be different. Have you ever noticed that when you change, your whole world changes? Everything and everyone seems different. Interesting, huh?
True realism. You determine your own odds in life. You're not a mere statistic, but an individual creating your own destiny—either mining or undermining life's possibilities by the way you think and act. You won't always get what you want even if you do your best. Sometimes circumstances or other people's wills prevent the fulfillment of your dreams. Even so, a person who brings love, care, and intelligence to all of life will create beauty and goodness—just as, realistically, a lazy, careless, stingy, fearful, or loveless attitude will bear different, more bitter fruit.
A realistic farmer knows what it takes to grow healthy crops, and labors lovingly to create the right conditions. Similarly, life, love, and relationships have requirements that need to be met if they are to flourish. Truly realistic people work to meet those demands in a good spirit. For them, realistically, bountiful harvests are most likely.


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Imagine a world where there is no drama on TV networks, multiplex movies, or performing arts centers. While that world would be monotonous, your family business should be drama-free!
Even when there are no family members involved, running your own business is difficult. When family members are involved, though, the difficulties can rise enormously.
It's not all sunshine and rainbows when you're working with relatives or friends. However, if you can get past the drama and personal feuds, operating a family business can be rather gratifying.
90% of family companies fail to pass down to the third generation. Family businesses have challenges for a variety of reasons, including personal and professional conflicts, poor recruiting practices, and a general lack of interest from one generation to the next.
Then there's the emotional turmoil. Many families already struggle to get along without having their livelihood and assets tied to community decisions. Typical issues in strategy and operations management in "regular" organizations are dwarfed by problems with family relations.
But if you put personal drama and strife aside, running a family business can be immensely rewarding.
If you run a family business, you'll need to take extra precautions to avoid burnout, maintain workplace harmony, and seek counsel from professionals outside the family.
What steps can a family business practitioner take for peace while running a family business? The full answer will be discussed in the article below
Read: Kintsugi - Japanese art of repairing broken pottery for your Family Business
Family drama and businesses
Some family business owners cope with power battles among family members, while others fight to stay on the same page and treat everyone equitably in the family firm.
There's also the issue of staff who aren't completing their tasks properly. "The biggest drama would be that jobs and roles can sometimes be forgotten, and anybody believes they're the new boss," one small business owner said.
Many family business owners have a hard time distinguishing between business and personal problems. "We try to set a rule that there is no business discourse at home," one small business owner says. If we do, there will be a certain day and time made aside for it. It's difficult."
"The biggest issue I've encountered with family businesses is the inability to transfer roles," said another respondent. Your role at work is very different from your role at home, and this needs to be made clear in many cases."
It's also difficult to clock out for the day when you run a family business. "I have a hard time leaving work for the day," one small business owner admitted. I'm still trying to strike a decent balance."
Do you agree with some of these points? Take a look at these suggestions for running a family business while avoiding the controversy.
1. Assign specific roles
In your company, both family and non-family people play a significant role. Designate and convey roles to ensure that everyone's responsibilities are crystal clear.
Verify that all members of your family and staff are aware of their roles and expectations. Create an organizational chart with your pen and paper, outlining the responsibilities of each family member. There will be no misunderstanding about each member's job in the company this manner.
Based on their skills and abilities, place the best people in the greatest positions. Aunt Kelly's belief that her son should take over as customer service manager does not imply that he has the necessary expertise or skill set.
To avoid short-term conflict and disappointment, it's simple to place family members in desired jobs. However, not every family member is capable of performing particular tasks.
Keep your options open when filling roles in a family-run firm. There could be superior talent out there who can contribute more.
Read: Improving Family Business Communication
2. Create a succession strategy
Your family business has been built on a lot of blood, sweat, and tears by you and your kin. But what happens when it's time to hand over the reigns to someone else? Create a succession plan to help your company plan for the future.
Succession is a problem for 40% of businesses in the United States. Unfortunately, if you don't have a plan in place, your company may not be able to survive.
According to another report, 70% of family-owned enterprises fail when they pass down to the next generation. Don't allow your mom-and-pop shop become a statistic.
Ask yourself questions such, "Who has the potential to head my company?" as you create your succession plan. What kind of owner and leader does my company require?
In most cases, succession planning is not a do-it-yourself project. Many businesses use a small business lawyer or a CPA to assist them create a strong plan. Consider enlisting the assistance of a business specialist.
Regularly revisit your strategy to maintain information current, especially when succession occurs.
3. Make Time For Your Family
Running a business may be difficult, especially when you're doing it with your family. It's possible that your patience will run out. You may also notice that you spend more time bickering than agreeing.
During difficult times, engage in enjoyable family activities.
Despite the fact that you manage a business together, work should not be your family's major priority 24 hours a day, seven days a week. Make time outside of work for your family. Participate in activities that can help you bond and de-stress. Take in a film. After work, go out to eat. Have a picnic with your family. Do whatever it is that you and your family enjoy.
While expanding your small business, form a team and have fun doing it. And keep in mind that you're all on the same team.
4. Deal With Workplace Drama
You've probably heard the expression, "Save the drama for your mommy." In this instance, you should keep the drama at home.
Allowing resentment to flow over into the workplace is not a good idea. Keep office drama to a minimum for the sake of everyone's well-being. Personal and family matters should not be discussed at work. Have a plan in place to defuse the situation if it becomes heated.
Now, I'm not claiming that you'll have no workplace drama. Whether your company is family-owned or not, you'll have to put out certain fires from time to time.
I experienced with workplace drama when I established Patriot Software, which specializes in accounting and payroll software. One of my employees threatened to beat up another, and another set fire to a laundromat.
And do you want to know what I've learned from these kinds of encounters?
Yes, you must deal with disputes. But don't dwell on them after you've dealt with them. Now is the time to move on.
5. Delegate Power to Non-Family Members
In order to strike a balance between family unity and economic success, enlist the support of non-family members to keep everyone in line.
As previously stated, family drama is a certain method to ruin your company. Give someone else authority to avoid turmoil and keep things neutral.
Assign a mediator if you have a non-family employee you trust. Have a non-family employee step in whenever the family dynamic interferes with business activities.
Read: Sibling Rivalry in Family Business
Family-owned enterprises should keep one thing in mind: it's not worth risking connections and your company's success in the long run.
You can only have so much family, after all. If you want to avoid workplace trouble with family members, talk it out before things get out of hand. Also, avoid bringing personal matters into the job.


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While they don't offer any additional features, Arturia's Limited Edition Creation Series versions of its DrumBrute drum machine and MicroBrute, certainly look a bit different. These feature a "shadowy recreation" of Michelangelo's The Creation of Adam, and offer a metallic, high-contrast livery.
Both instruments are currently available for pre-order, and will ship at the beginning of July. Prices are €449 for the DrumBrute Creation and €299 for the MicroBrute Creation; that's the same as the standard versions, so if you want to stand out from the crowd, you won't have to pay a premium to do so.
Find out more on the Arturia website.


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American 'Karens' are having public meltdowns over wearing face masks
It seems many Americans hate being told what to do.
Rejecting authority in favour of individual freedom appears to be an intrinsic part of the cultural DNA of some US citizens.
So it's no surprise that being told to wear a face mask in public has become a deeply politicised issue – even as the US battles the worst coronavirus infection rate in the world.
Face masks have come to symbolise a heated debate between those willing to follow official health advice and those who feel it violates their freedom.
There are few people more outraged about being told to wear face masks than Karen – the internet's nickname for stereotypical, entitled white women.
Karen can often be seen asking to speak to store managers, threatening legal action or posting inspirational quotes on Instagram.
More recently in 2020, Karen has been spotted hoarding toilet paper and dismissing the coronavirus pandemic as an issue that has been blown out of proportion.
Now, she is throwing tantrums after being told to wear a face mask.
And social media is loving it.
KAREN AND HER TEARS … pic.twitter.com/HP0Ud21LFO
— gregarious 🏳🌈 (@gryking) June 27, 2020
Welcome to Dallas, Texas where the weather is sunny and the #Karens act funny 😆 #KarensGoneWild #Karen #KarenOfTheDay #KarenStrikesAgain #WearAMask pic.twitter.com/NgQkaKHjq0
— Karens Gone Wild (@karensgonewild_) June 28, 2020
"I never threatened him." Hear from woman who was denied service at a Clairemont Starbucks for refusing to wear a mask. She publically shamed the barista. A Go Fund Me Page on his behalf is now over $22,000. She says she's getting death threats. #nbc7 & https://t.co/ylvk5rP6Vf pic.twitter.com/gCREw0LR5V
— Artie Ojeda (@ArtieNBCSD) June 25, 2020
Hilarious public meltdowns aside, resistance to face masks in the US comes with a more sinister side.
Though face masks are not foolproof against COVID-19, a growing body of research suggests that wearing one in public can dramatically reduce the spread of the disease.
It's pathetic that we're at a point where we have selfish idiots who refuse to wear a mask with over 2 mil infections & 123K people dead. pic.twitter.com/HRJtc6grwW
— 🌊MasksSaveLives😷 (@mammaTam55) June 24, 2020
In the US, where case numbers exceed a staggering 2.6 million and more than 128,000 people have died, any action designed to slow the virus is being encouraged by health authorities.
President Donald Trump, however, has so far resisted wearing a face mask – a stance that is often copied by his supporters.
Darren storms the supermarket!! He rages! This dude was not happy he was told to wear a mask at the grocery store. Of course this was in Florida! pic.twitter.com/ZnyVxGMs2T
— Perez (@ThePerezHilton) June 22, 2020


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Registered user since Tue 22 May 2018
Smita Ghaisas is a Chief Scientist and a Distinguished Engineer at TCS Research, Tata Consultancy Services Ltd (TCSL). She leads Data Driven Requirements Engineering (RE) Research. She additionally leads the technical task force for an enterprise-wide initiative in AI powered governance of contractual obligations at TCS. For this initiative, she has defined a technical strategic solution and roadmap and deployed it in coordination with the CIO's office, Delivery Excellence Group, and Corporate Legal at TCS.
Her current interests include creating scalable AI solutions that solve non-trivial practical problems in large enterprises.
She has served on program committees of flagship conferences such as ICSE, FSE, and RE and was the co-chair of the Industry Innovation track of RE 18. She also serves on the Editorial Board of the IEEE Empirical Software Engineering (EMSE) journal. For her achievements, she has been designated as a Distinguished Engineer, an award conferred in recognition of her contribution to enhanced research and IP footprint and value creation for her company.
View general profile


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BridgeBio Pharma Inc. terminated its bid for the remaining stake in Eidos Therapeutics Inc. as it failed to reach an agreement with a special committee of Eidos' board.
Palo Alto, Calif.-based BridgeBio, which develops therapies for genetic diseases, owns about 66% stake in Eidos. The company's final offer was equivalent to 1.5 BridgeBio shares for each Eidos share.
Initially, BridgeBio offered 1.3 shares for each Eidos share. A special committee of Eidos board unanimously rejected the offer in September.
Under the offer, Eidos' shareholders had the option to choose between receiving their consideration as all-stock, cash and stock mix, or all-cash, such that the transaction is not more than $110 million.
San Francisco-based biotechnology company Eidos develops treatments for a progressive condition associated with the buildup of abnormal deposits of a certain protein called amyloid in the organs and tissues.
Eidos' stock price was down 6.7% to $36.01 as of 1:43 p.m. on Oct. 14.


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When all hope is lost and humanity's fate hangs in the balance, the Master Chief is ready to confront the most ruthless foe he's ever faced. Step inside the armor of humanity's greatest hero to experience an epic adventure and explore the vast reaches of Zeta Halo, from stunning heights to mysterious depths below the ring. Rescue UNSC marines to gain reinforcements in your fight against a fearsome enemy known as "the Banished." Enjoy true Spartan freedom in the biggest, most wide open and adventure-filled Halo experience yet, launching December 8 2021.
For more information on Halo Infinite, head to: xbox.com/haloinfinite
#Halo #HaloInfinite #HaloInfiniteCampaign
Connect with us!
Web: https://halowaypoint.com
Twitter: https://twitter.com/Halo
Instagram: https://instagram.com/Halo
Facebook: https://facebook.com/Halo
Twitch: https://twitch.tv/Halo
Discord: https://discord.gg/Halo
Halo Support
Website: https://aka.ms/HaloSupport
Twitter: https://twitter.com/HaloSupport


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We are Adirondack Veterinary Service
From the moment you walk through our covered porch entrance we do everything to make sure you and your pet feel at ease. Your pet gives you wholehearted and unconditional love so when they need medical care we want you to know you came to the right place. We only see one patient at a time so our doctors and staff can give you and your pet their undivided attention. We strive to make personalized care our forte!
Our practice was established in 1992 as a large animal service to local dairies and horse stables in Oneida County, New York. In the year 2000, after an extensive remodel to the building we are in, we moved to our current facility and expanded our care to include dogs and cats.
Enjoy browsing through our site. In it you will find useful information about our staff and the services we provide. In addition, there are articles about equine and pet care you can peruse. We have also provided several links to other sites that promote optimum pet and horse health. Feel free to contact us with any questions you might have about the services we offer or pet health information you might need.
Clinic Hours
Monday-Tuesday, 8:00am – 5:00pm
Wednesday, 8:00am – 6:00pm
Thursday, 8:00am – 5:00pm
Friday, 8:00am- 5:00pm
Sat. & Sun: Closed
Emergency Services
Mon-Sun: Veterinary Medical Center
5841 Bridge St.E.
Syracuse, NY
View map
(315) 446-7933
Meet our Experienced Team
Dr. Louis Calabrese
Dr. Lou, a graduate of Michigan State College of Veterinary Medicine, has been practicing for over thirty years. Initially an equine specialist he expanded his practice to include small animals after moving to the current Rome-Taberg location. Dr. Lou is an avid sportsman who, when not serving the needs of your furry friends, can be found on local lakes and streams fishing and as he will sharehopefully catching.
Dr. Joseph Dreels
Dr. Joe was born and raised here in Central New York and graduated from the highly acclaimed College of Veterinary Medicine at the University of Illinois. He has been dedicated to the care of large and small animals in a career spanning nearly four decades. An avid golfer and now semi-retired he attends to patients here in our facility one day a week.
Nancy Salsberg
LVT (Licensed Veterinary Technician)
Nancy studied Veterinary Technology at SUNY Delhi. She joined the Adirondack team in the fall of 2018. Nancy's knowledge and expertise gained from years of practical experience have proved to be an invaluable resource. Our clients are often heard complimenting her by saying "Nancy treats our pet as if they are her own". Nancy's home furry family includes a Belgian Malinois, Chey (Chy) and two cats, Fyre & Angel.
Joyce H.
Office Manager/Client Services Representative
Joyce has been the grease keeping the wheels moving at Adirondack Veterinary Service for twenty-four years. She coordinates client services and accounting activities supporting veterinary care for all your Pets. When not at the clinic Joyce keeps herself busy at home taking care of six long haired Chihuahua's and two Pomeranian's.