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With one form to rule them all, the Gravity Hopper Multisite Global Forms plugin is the ideal solution for distributing Gravity Forms to your WordPress multisite network. Create. Distribute. Sync. Receive.
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The plugin restricts users from editing attributes of a form that are considered global (i.e. general form settings, form fields, and confirmations). Your network users will be allowed to customize form feeds (including notifications not deployed with the form and unlocked feeds added by other add-ons). Such customizations will not be overwritten when a global form is synced. All form entries on the child site will remain.
Do we play nice with other Gravity Form add-ons?
Multisite Global Forms should work alongside other Gravity Form add-ons, but has not yet been tested thoroughly with all native or third-party extensions. Note that you will want to ensure any add-ons in use on the form, will need to also be active on the network sites. If you encounter a conflict, please submit a support ticket and we'll check it out.
Are large networks supported?
Mostly. At the moment, performance in a larger network environment is likely dependent upon your server infrastructure. The network overview dashboard is currently operational only on networks with less than 200 sites. We've not yet had opportunity to further optimize the plugin for use on larger networks.
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If you have a form set to send entries from the network sites to the primary site, all feeds (notifications, payment processing, etc.) will be run on the child site. No feeds will be run on the network's primary site.
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When a global form is trashed, it is moved to the trash on all sites. When a global form is deleted, it is permanently deleted from all sites. If you want the form to remain available on all sites, then you should first unset the global flag for the form.
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Yes and no. We're working on this. There are some inherent limitations in handling feeds. Certain feeds have settings that can easily be ported to other sites. Other feeds are configured in a way that they should not be copied to a site other than that on which it was created. At the moment, Stripe feed syncing has been enabled and is being used as a testing ground for how (and to what extent) this feature should be available. Prior to deployment, you can lock or unlock specific feeds for editing by the site owner.


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Turn Around 5-7 Business Days , Rush
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Seminar (WS 2009/10)
Principles of Biological Development
Biological development typically starts from a single fertilized cell, follows a precisely regulated sequence of steps and finally leads to an intricate pattern of differentiated tissues in the adult organism. It has turned out that biological development can be interpreted as cooperative phenomenon emerging in a system of interacting cells and molecules. Accordingly, mathematical modelling is essential to understand key steps in the developmental dynamics as cell division, signalling, differentiation, segmentation or regeneration. In the seminar, we are focusing on the question: What are the mechanisms of self-organization that govern the pattern formation orchestra and how can suitable mathematical models be analyzed? By means of talks, discussions and computer simulations, key questions of biological development and suitable mathematical models will be introduced.
The seminar is intended for undergraduate and graduate students in mathematics, biology or computer science who are interested in this highly interdisciplinary application field.
- Flyer (pdf) with the Objective of the seminar.
- Time: 4 Monday afternoons 14.00-17.00: Nov. 16, Dec. 14, 2009 and Jan. 18, Feb. 8 2010
Kickoff meeting and distribution of talks: October 26, 14.00-15.00, INF-1096 - Location: INF-1096, Computer Science Dept. of TU Dresden at Nöthnitzer Str. 46
- Organizers:
Christopher Antos, Center for Regenerative Therapies Dresden
Lutz Brusch, ZIH, TU Dresden
Andreas Deutsch, ZIH, TU Dresden
Andy Oates, Max Planck Institute of Molecular Cell Biology and Genetics (MPI-CBG) - Contact: Andreas Deutsch, Tel. 463-31943
- In this semester the related lecture "Introduction to Mathematical Biology II" takes place. More information.
- Program of the Seminar talks: download here.
click here for older and future lectures
(to download lecture material and papers please proceed here)


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Home>Products>Custom-made Martin Guitar>Martin M130 Silk and Steel Custom Acoustic Guitar Strings
Martin M130 Silk and Steel Custom Acoustic Guitar Strings
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Gauges 11.5-14-23-28-38-47.
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I actually put these strings on an old guitar that was my dads......from WWII and it sounds pretty darn good.Martin M130 Silk and Steel Custom Acoustic Guitar Strings
.I get a couple of sets of these when I haven't played for a while and have to build up my callouses.
Martin M130 Silk and Steel Custom Acoustic Guitar Strings
.I absolutely love these strings. I put them on a guitar that up to that point I had intended on selling, it just never had the right sound or feel. But with the Martin M130 Folk Silk & Steel strings, it has vastly improved the sound and feel of my guitar.
I have sold my more experienced friends on these strings just by playing with them-- they said they had never felt anything like them, loved the sound, and then continued to play on my guitar all night. :-)
The feel is soft and easy on the fingers, strings bend with more ease, extending the time you can physically spend with your guitar (especially important for beginners who usually complain a lot of finger fatigue, or older musicians with arthritis, or nerve damage like I have). The sound is a lovely mixture of steel highs and mellow lows. I originally bought these strings because I read that they were a mellow alternative, somewhere between Phosphor-Bronze and Nylon (and my guitar was overzealous in the treble and lacking in the bass). What I did not expect was the overall range-- soft and mellow but well-voiced bass strings, and ethereal high notes on the top strings. I am well impressed!
These strings have lasted surprisingly well. I put them on my guitar 3 1/2 months ago, and play multiple times a week (sometimes 7 days straight and other times missing a week at a time), and the sound and intonation still surprise me. They stay tuned very well (even on my more "entry level" guitar), and have not yet developed that dreaded "flatness" that seems to start creeping up on my other strings within weeks of use.
Would I buy these again? You betcha. In fact I just ordered another 3 sets for myself and 2 as gifts. Enjoy!
Martin M130 Silk and Steel Custom Acoustic Guitar Strings
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I have several acoustic guitars including an early 90's Gibson Chet Atkins solid body and wanted to change the strings. I put these Silk and Steels on and whoa Nelly what a difference! I think they are very understated. If you're plugging in a solid body or other acoustic they're perfect. Unamplified on a box guitar I'd prefer something else. This is not a knock! They really sound good to my ears, very lively, good tone etc, and easy on the fingers. To me they're a special purpose string. My Chet needed these as they are very forgiving and sound good for vocal accompanyment for my seated acoustic solo act. Not loud or squeaky sounding and definitely not screechy if you know what I mean? With the Chet volume is not a problem. I'll keep using these or some like them on the Chet, but something else on my others for unamplified volume. Part timer out!Martin M130 Silk and Steel Custom Acoustic Guitar Strings
.These were the strings that Martin recommended for my 1954 00-17 Martin. However I plan to put on the 1400 strings to protect the holes at the bridge. Same strings but protection at the bridge area with silk wrapping. Otherwise they are great low tension strings for older guitars that cannot take the tension from ie light strings.
Martin M130 Silk and Steel Custom Acoustic Guitar Strings
.I use these strings on an acoustic folk guitar and play only fingerstyle. These strings give a warm but defined tone, with balanced response - I've found phospher bronze strings for instance to have overpowering basses for my playing. I play professionally and daily, and these strings last 3-4 months.
Martin M130 Silk and Steel Custom Acoustic Guitar Strings
.I use these stings for my Fender California Elvis Presley Signature guitar and play folk music for myself and family. These strings sound fantastic and are easy on the fingers.
Martin M130 Silk and Steel Custom Acoustic Guitar Strings
.Great strings my acoustic 4hrs at a show that's a four hr show I love the feel on my fingers
Martin M130 Silk and Steel Custom Acoustic Guitar Strings
.I was surprisingly impressed with these strings. I have shifted to lighter gauge strings in recent years for playability. However since I tried what I considered are the sister strings to these, the Martin FX130 (silk and phosphor), I figured I'd try these out.
When I opened the package, I was apprehensive about the tone of these strings because they appear more rope like than what I typically associate with steel strings. I was also a bit surprised by the pure burning silver color of the strings (as a result of the steel coating i imagine), I have since grown to like the contrast of them on my guitar.
Enough about aesthetics, few people buy strings based on how they look. The tone was incredible to my ears. It has much more overtones (which I usually dislike) than I've ever heard from any other strings I've tried. The tone was further complex by the fact that it had a hint of a classical guitar sound (not enough to make it displeasing for steel string players)
From a playability standpoint, I found it required a touch higher pressure from my typical extra light gauges (.010) as compared to these (.0115).
The longevity of these strings may be it's only down fall. I don't excrete much oil from my hands (and strings seem to have about 25%-33% more life with me than my friends), and from daily playing of about 1 to 2 hours per day, over the course of a week, I found that a light tarnish has already begun to form. I imagine these strings will only last 3 weeks at this rate.
Martin M130 Silk and Steel Custom Acoustic Guitar Strings
.If you like the vintage guitar sounds of the folk era, these are your strings!
They are a little softer and quieter than bronze or brass strings. The timbre is somewhere between a steel-string guitar and a nylon string. The plain strings are sharp and clear, and the wound strings have the gorgeous, broader tone that comes from the silk winding.
Silk and steel strings were the "Gold Standard" in the folk era of the 60s.
They're easier on your fingers, and the mellower tone leaves space in the mix for your voice.
If you tend to play vigorously with a pick, either lead or rhythm, these may not be the strings for you. They don't have the punch or definition of bronze, brass or monel steel.
But if you play fingerstyle or strum gently, these are about the sweetest-sounding strings there are, especially for accompanying voice.
There's a reason they're still making them after all these years!
Martin M130 Silk and Steel Custom Acoustic Guitar Strings
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IES Grant
Title: | A Longitudinal Efficacy Study of the Montessori Preschool Model on Academic and Social-Emotional Outcomes | ||
Center: | NCER | Year: | 2018 |
Principal Investigator: | Faria, Ann-Marie | Awardee: | American Institutes for Research (AIR) |
Program: | Early Learning Programs and Policies [Program Details] | ||
Award Period: | 5 years (08/01/2018 - 07/31/2023) | Award Amount: | $3,294,232 |
Type: | Efficacy and Replication | Award Number: | R305A180181 |
Description: | Co-Principal Investigator: Lillard, Angeline Purpose: The purpose of this study is to investigate the impact of Montessori preschool education on children's kindergarten readiness skills. Although the Montessori model has expanded into public schools and Head Start programs in recent years, no large-scale evaluation of the efficacy of the Montessori preschool model for developing children's academic, social, and emotional skills has been conducted. In this project, researchers will compare children who enter Montessori at age 3 and attend for two years prior to kindergarten with their peers who participate in other early care and education experiences during those two years. Project Activities: Researchers will evaluate the impacts of participating in a Montessori program on students' academic and social-behavioral skills. They will randomly assign children to the Montessori program or a waitlist control group within lotteries at each preschool program site. The researchers will collect data and conduct analyses to compare outcomes for students who were offered enrollment in a Montessori program with the outcomes for students who participated in the lotteries but were not offered Montessori enrollment (and attended other types of preschool programs instead). They will also conduct a cost effectiveness study of the public Montessori preschool model. Products: Researchers will produce evidence of the efficacy of Montessori preschool education to improve children's kindergarten readiness skills, prepare short research briefs, infographics, blog posts and webinars to share findings with practitioners, and produce peer-reviewed publications. Structured Abstract Setting: The study will take place in Montessori and non-Montessori public preschool programs, in six racially and socioeconomically diverse, urban, and suburban districts in Dallas, Texas; Houston, Texas; Washington, DC; Baltimore, Maryland; Hartford, Connecticut; and New Haven, Connecticut. Sample: The study sample will include 18 Montessori public preschool sites and 666 children from racially and ethnically diverse backgrounds. Intervention: This study will evaluate the Montessori model for preschool, which is based on the theory that young students learn more by action than by thought. Primary classrooms are multiage, including 3- to 6-year old children. Montessori teachers provide a prepared classroom environment filled with appropriate materials, but students have considerable freedom to select the activities they engage in each day. Research Design and Methods: Researchers will use a blocked individual random assignment design, where children are randomly assigned within lotteries to either attend Montessori at age 3 or assigned to a waitlist control group within each site. Each public Montessori preschool in the study (18 in all) will have its own lottery. The researchers will follow the same cohort of children for three years (fall 2019 to spring of 2022). The researchers will administer direct child assessments, collect teacher report data, conduct classroom observations, and collect administrative data from school districts when children enter kindergarten. They will also examine the relationship between fidelity of implementation of the Montessori model and impact, conduct a cost effectiveness study, and disseminate study findings. Control Condition: Students from the Montessori waitlist who are not admitted to the program will serve as the control group. These students will attend non-Montessori preschool programs or participate in other home care arrangements. The research team will track students in the control condition and document their enrollment in non-Montessori preschool programs. Key Measures: Primary measures include standardized direct child assessments of children's academic and social-behavioral skills, classroom observations, and measures of fidelity of implementation fidelity. Direct assessments will include subtests of the Woodcock-Johnson tests of achievement, the Rubin Social Problem Solving task, a theory of mind scale, the Social Skills Improvement System Rating Scales, the marshmallow task (which assesses self-regulation), and the Preschool Learning Behaviors Scale. Classroom observation measures include the Classroom Assessment Scoring System and the Developmental Environmental Rating Scale. Data Analytic Strategy: Researchers will conduct multilevel analyses to estimate the impact of being offered admission to a Montessori school through a lottery. They will assess the impact of Montessori at the end of each of the three years of the study and conduct growth curve analyses to estimate the impact of Montessori across three years. The research team will also conduct complier average treatment effect analyses to estimate treatment effects on those who attended Montessori. |
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text: Home › Forums › Game Frame › Technical Support › v2 firmware using neopixels This topic has 1 reply, 2 voices, and was last updated 7 years, 9 months ago by Jeremy Williams. Viewing 2 posts - 1 through 2 (of 2 total) Author Posts May 25, 2016 at 1:27 pm #2641 aromanoParticipant HI, I just finished building my own and I noticed you have v2 firmware.. I'm have two issues… the entropy libabry I downloaded doesn't seem to be compatible with the entropy library you used in your firmware ( which version entropy did you use? ) also it seems that the firmware is setup for some other led thats aren't the ws2812 neopixels… is that an easy change to get this working with my display? thanks ! May 25, 2016 at 3:57 pm #2643 Jeremy WilliamsKeymaster V2 software is designed for the Teensy LC and APA102C LEDs, the hardware used in the Game Frame redesign launched this year. Neopixels are incompatible with the IR Remote control, since they tie up the system interrupts, but if you want to try it out you can just change the LED type from APA102 to WS2812. I used the version of Entropy installed with Teeensyduino. Author Posts Viewing 2 posts - 1 through 2 (of 2 total) You must be logged in to reply to this topic. Log In Username: Password: Keep me signed in Log In


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EZQ System for In-Person Meetings
In-Person Meetings: Join a line from anywhere!
In-person services are now available! Don't get stuck waiting in line, join the line from anywhere! The new EZQ (Easy Queue)/Qless system allows you to get in line from anywhere so that you have more time to study, get to class, grab a coffee, visit with friends or soak up the sun. Don't worry, you'll receive wait time updates so you know when to visit the office for your meeting. It's the smarter way to get in line.
The following offices use EZQ to schedule in-person meetings:
- Financial Aid
- Business Office
- Success Center
- Admissions
- Advising
- Bookstore
How it Works
- To meet in-person, join a line online, use the mobile app, or text "quinsig" to 508.315.6028.
- Once you have joined a line, you will get an text message that says "You have joined the line. X minutes until your appointment."
- Once it is your turn, you will get "It's your turn! Go to …..". At this time you may proceed to the appropriate office or location.
- If you do not appear at the location in time, you will get a message explaining, "Your appointment has expired you have 15 minutes to rejoin the line by texting J".
- If you do not rejoin the line, you will get a "NO Show" text and have your appointment cancelled.
In-Person FlexAppointment Scheduling Process
- Make an appointment for an in-person meeting using the app, Web site, or kiosk. You can only schedule one active FlexAppointment in the system at a time.
- You will receive an email and text message confirming your in-person appointment.
- 24 hours before your in-person appointment, you will receive an appointment reminder email.
- The morning of the in-person appointment, you will receive a text reminder.
- 30 minutes before your in-person appointment, you will receive a text reminder.
- You may proceed to the designated office or location of your in-person appointment.


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the mma news
UFC: Ultimate Fighter house goes on the market for $5 million
Jay Rock -
The Ultimate fighters has been airing on Television for 13 years now and has completed 27 seasons and heading to it's 28th this August...
UFC: Conor McGregor's boxing coach Owen Roddy confident that McGregor can exploit both Khabib Nurmagomedov and GSP's 'flaws'
UFC lightweight champion Khabib 'The Eagle' Nurmagomedov might probably be the frontrunner to face former featherweight and lightweight champion Conor McGregor. However, McGregor's boxing...
UFC: Brian Ortega opens up about failed drug test in UFC debut
Brian Ortega (14-0) will finally get his chance at gold at UFC 226, next weekend. Brian Ortega has overcome more than adversity inside the octagon,...
Latest news
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The gap between the last Round of 32 games on Sunday and the first Sweet 16 games on Thursday always feels like it's about three months long. You go from having action flying at you from all directions for 12 hours a day to absolutely nothing in the snap of a finger. It's an abrupt revocation of joy that conjures up memories of the final present on Christmas morning and the knowledge that only dinner and forced conversation with over-served relatives lay ahead.
The joy returns in just a few hours when the Sweet 16 tips off with Miami and Marquette at 7:15 p.m. ET (check out the full schedule). Here's everything you need to know between now and then in order to be properly educated.
1. Florida Gulf Coast has already made history, and is looking to make more
By shocking Georgetown and San Diego State on the tournament's opening weekend, the Eagles became the first team seeded higher than 14 to ever advance to the Sweet 16. The 1986 Cleveland State Vikings and the 1997 Chattanooga Mocs, both 14 seeds, had previously been the worst-seeded teams to crash the Regional semifinals. Six 13 seeds, including Ohio last season, have advanced out of the tournament's first weekend, but none have wound up winning their next game.
The 2002 Missouri Tigers, a 12 seed, remain the worst-seeded team to ever play in a Regional championship game, which means...
2. La Salle can also make history
FGCU's run has resulted in an understudy role for La Salle, which has become the second "First Four" team in three years to win a trio of games during the opening week of the tournament. If the Explorers find a way to beat Wichita State on Thursday, then the comparisons to VCU, which went from the First Four to the Final Four back in 2011, will be ratcheted up a notch.
Though La Salle is actually a worse seed than VCU (11) was when the Rams made their run, this isn't the usual Cinderella story of a no-name program coming out of nowhere to capture America's attention. Though it had been 23 years since the Explorers last won an NCAA Tournament game, this is still a program which won a national title in 1954 and was one win away from cutting down the nets again the year after. That said, the 1955 run was the last time La Salle won more than a game in the big dance.
3. Rick Pitino has owned the Sweet 16
No. 1 overall seed Louisville was the only truly dominant team during the tournament's opening weekend, a trend which is likely to continue on Friday if Rick Pitino's Sweet 16 history is any indication. Not only is Pitino 10-0 in the round, his teams have won all 10 games by double digits.
The list:
6. Providence 103, 2. Alabama 82 (1987)
2. Kentucky 87, 3. Massachusetts 77 (1992)
1. Kentucky 103, 5. Wake Forest 69 (1993)
1. Kentucky 97, 5. Arizona State 73 (1995)
1. Kentucky 101, 4. Utah 70 (1996)
1. Kentucky 83, 4. St. Joseph's 68 (1997)
4. Louisville 93, 1. Washington 79 (2005)
3. Louisville 79, 2. Tennessee 60 (2008)
1. Louisville 103, 12. Arizona 64 (2009)
4. Louisville 57, 1. Michigan State 44 (2012)
That's an incredible average margin of victory of 22.0 points.
4. Coach K and Tom Izzo will have their tournament rubber match
There have been just three Sweet 16s since Tom Izzo took over at Michigan State in 1996 that haven't featured either his Spartans or Mike Krzyzewski's Duke Blue Devils. Despite this, the two titans of the sport have met just twice in the NCAA Tournament.
In 1999, Elton Brand scored 18 points to lead Duke past fellow top seed Michigan State, 68-62 in the Final Four. The Blue Devils would go on to lose to Connecticut in the national title game two days later. Izzo exacted a little bit of revenge six years later when the fifth-seeded Spartans upset No. 1 Duke in the Sweet 16, 78-68. If the Blue Devils score 68 again when the two meet on Friday, well, I don't know how you should react, but it'll be weird.
Things get a little bit more one-sided when you look beyond the tournament, however, as Coach K owns a 6-1 all-time advantage over Izzo. All seven of those games have taken place while Krzyzewski has been at Duke and Izzo has been at Michigan State.
5. Indiana and Syracuse will meet in a 1987 title game rematch
Thursday night's meeting between the Hoosiers and the Orange will be just the fourth between the two storied programs since they played one of the most memorable championship games in history. With Syracuse needing just one stop to secure its first national title, Indiana's Keith Smart got free and delivered what is still referred to simply as "The Shot" around Bloomington.
6. The game is a bit more personal for Syracuse's Brandon Triche
The man Smart is hitting the game-winning shot over in that video is Howard Triche, the uncle of current Orange senior Brandon Triche. The Triches say the shot isn't one of those things that they talk about much, but Howard -- who was a senior in 1987 -- recently predicted that his nephew's college story will have a different ending than his did.
"This is his dream," Howard said. "This is where he's going to. It's going to turn out different for him."
7. Miami's Reggie Johnson will not play this weekend
The Hurricane center had a surgical procedure to repair a minor meniscus issue on Tuesday, and will not play in this weekend's East Regional games. Johnson, a senior who averaged double figures in both his sophomore and junior campaigns, has seen a drastic decrease in production this season, thanks in large part to a broken thumb he suffered just before Christmas. Johnson scored seven points and grabbed 15 rebounds in Miami's first two NCAA Tournament games.
8. Mark Lyons vs. Aaron Craft will be fun
Perhaps the most intriguing individual matchup in the Sweet 16 will be the showdown between Arizona point guard Mark Lyons and Ohio State's Aaron Craft. Lyons, who is averaging 25.0 ppg in the big dance, is one of the better pure scorers in the country, but the Xavier transfer has had significant issues with turnovers throughout this season. Craft has an earned reputation as the best on-ball defender in college basketball. He held Iona's MoMo Jones, a similarly-skilled point guard who also played at Arizona, to 3-for-14 from the floor with zero assists and four turnovers in Ohio State's tournament opener.
The game won't be as simple as Craft vs. Lyons, but it's hard to envision one of the players being dominated by the other and still being able to celebrate a victory.
9. Florida is the biggest Sweet 16 favorite
Vegas currently has the Gators as a 13-point favorite over Florida Gulf Coast, the largest spread of any Sweet 16 game. The second-biggest favorite is No. 1 overall seed Louisville, which is favored over Oregon by 10 points.
10. If Marquette beats Miami, Buzz Williams will probably dance
It's sort of his thing.
11. Kansas needs Ben McLemore to break out of his funk
The Jayhawks turned a nine-point halftime deficit against North Carolina into a 12-point victory, and did so with their best player on the bench for nearly the entire second half run. McLemore finished that game 0-for-9 from the field and scored just two points.
"I've talked to enough people (and) coaches over the years that say you don't (bench) your best player or leading scorer," Kansas coach Bill Self said after the UNC game. "We were actually better during that stretch. And Ben was the biggest cheerleader we had."
But McLemore's struggles aren't limited to last weekend. In his last four games, the freshman All-American has made just 8-of-26 shots and is averaging only 7.0 ppg. That has to change if the Jayhawks are going to be able to take care of business this weekend despite a drastic spike in the level of competition.
12. Wichita State received a surprise inspirational speaker this week
Wichita State hadn't even arrived back on campus following their massive upset of top seed Gonzaga before they got Tebow'd (am I using that right?).
"After we had gotten off the plane a gentleman taps me on my shoulder and says, 'Tim Tebow would like to address your team.'" Shockers coach Gregg Marshall recalled. "There was no connection, other than the fact that he was in Wichita to load up for fuel. He congratulated our players and said he watched our game. He told us not to lose that fire and that we'd remember these moments the rest of our lives."
Tebow would know, based on his own extensive personal NCAA Tournament experience.
13. Russ Smith and Mark Lyons are the tournament's (active) leading scorers
Temple's Khalif Wyatt dropped 31 in back-to-back games before the Owls were bounced by Indiana in the Round of 32, a scoring average unlikely to be surpassed by any player left in the tournament. Still, the tournament's active leading scorers are Russ Smith of Louisville and Mark Lyons of Arizona, both of whom scored 23 and 27 points in their first two tourney games.
14. If Florida Gulf Coast can hang in there early, they'll have a chance late
Bill Connelly, take it away.
On the flipside, Florida has had basically one weakness in 2012-13. The Gators have decimated almost every team with whom they crossed paths this season, but they have played six games decided by single digits ... and lost all six. It is the reason they were only a 3-seed in the NCAA Tournament despite statistical dominance. It doesn't doom them to failure in the NCAAs -- among other things, six games isn't much of a sample size -- but it certainly suggests that, if the game is close in the final minutes and FGCU is playing loose and effective basketball, the edge might turn ever-so-slightly toward the team from Fort Myers.
15. Rick Pitino says his team's game with Oregon is a "coin flip"
Pretty much everyone agrees at this point that the selection committee flubbed up by dealing Oregon a No. 12 seed, but Pitino might be going just a tad overboard with his Duck-lovin'.
16. Four of the five highest-paid coaches in the game are in the Sweet 16
That would be Duke's Mike Krzyzewski, Louisville's Rick Pitino, Kansas' Bill Self and Florida's Billy Donovan. The one absentee? John Calipari, who failed to get his Kentucky team into the tournament a year after winning the national championship.
More in College Basketball:
• Get ready for an all-B1G Final Four
• Bill Connelly: Here's how FGCU beats Florida
• NBA Draft: Can Ben McLemore get back on track?
• Sweet 16 power rankings: Cards still on top
• Printable bracket for March Madness


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For anyone looking for Dog Training, we offer hands on group lessons. We're running a Holiday Special @ $85 per session, our group sessions usually last 1 - 2 hours and you will get to work one on one with our main instructor. *Free photo shoot with every lesson.
We offer obedience training and protection dog training.
Mention this ad to get the Holiday Special.
520-840-4345 (texting preferred)


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Department of Chemical Engineering
Advertisement Number: P.Rect/R&D/2023/12
Indian Institute of Technology, Kanpur (IIT Kanpur) invites applications for the post of Project Scientist-I in a SERB/DST sponsored Project on "Ab initio Modeling of Molten Metal Batteries". We are looking for motivated and talented candidates with prior experience with density functional theory calculations (preferably in VASP or CP2K) and Catalysis. Coding in C/C++ and familiarity with Linux environment is also highly desirable.
Position Details:
The applicant may contact Dr. Vishal Agarwal (firstname.lastname@example.com) for any further details. Please do not send application to this address.
The appointment is purely temporary and on contractual basis.
Selection: The selection committee approved by IIT Kanpur reserves the right to fix suitable criteria for short listing of eligible candidates satisfying qualifications, experience and the recommendations. Only short-listed candidates will be interviewed (online). If shortlisted, copies of relevant certificates will be required, and be checked against original certificates at the time of interview. Candidates having prior experience in ab initio MD simulations in CP2K or VASP will be given preference.
Job Responsibilities: The successful candidate would be the key person in driving the project along with the PI. Additionally, the candidate should assist the PI running the laboratory and guiding the research of PhD students.
Applications: Application should be submitted by filling the form in the link below on or before Feb 1st, 2023:
Dr. Vishal Agarwal and Dr. Raju K Gupta Department of Chemical Engineering Indian Institute of Technology, Kanpur Uttar Pradesh-208016, India E-mail: email@example.com; ph: +91 512 259 6895


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Now on sale at 2019 Dead and Co. tour prices, this limited series of face mask/scarf/tapestry/bandana prints features Jerry Jaspar's Laughing Jack and Grateful Hug.
Each mini tapestry represents a limited edition of one, a unique art print. Useful for, but not limited to headband, neck scarf, face mask, belt, pet scarf, lampshade, monitor cover, framed art, handkerchief, festival flag, blindfold, or all these combined. NOTE: If you are framing or using the print as an art piece, do not wash it. Use cold water and hang dry if you're wearing the scarf. Keep it out of direct sunlight, which bleaches dye. Due to the nature of tie dye, your unique piece will vary in color and pattern from those shown. We invite you to a virtual tour of our stock and studio via phone apps like messenger or WhatsApp. If Jerry is available he'll be grateful to meet you in person. Thanks for checking us out!


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Often forgotten, but certainly worth your while: gutter maintenance
Perhaps it is because this a greenhouse component is not really in sight. And perhaps it is also because it is not everyone's favourite job. We are talking about greenhouse gutter maintenance. This is often postponed for a little longer than is good for the quality of a very important part of your greenhouse. No worries: Alumat Zeeman to the rescue!
We may not give it any thought for days on end, but that 'simple' gutter has a lot to endure. The burning sun, which eventually affects the material. Excessive rainfall, which has been particularly heavy in recent years. Heavy packs of snow. Or dirt from autumn leaves. Just as every component of your greenhouse is deserving of attention, the gutter also requires maintenance from time to time. A good rule of thumb is: lubricate your gutter once every five years.
What do you need?
With summer just around the corner, this is the best time to work outside. Alumat Zeeman makes life easy for you because it can supply you with everything you need: a good quality coating (yes, restored to our product range by popular demand), brush heads, greasing brushes and gloves. After all, isn't it true that good equipment is half the battle won? Order the equipment you need directly from stock. All the best on your roof!


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A Brief History of Dixfield, Maine
Text by Charlotte Collins
Images from Dixfield Historical Society
Town of Dixfield seal, 1988
Dixfield Historical Society
Following the Revolutionary War, the Commonwealth of Massachusetts needed to raise money to pay off its huge war debts. The Committee of the State of Eastern Lands became the vehicle for veterans to obtain new lands in the Province of Maine (then owned by Massachusetts). Land speculators swarmed all over Maine surveying its natural resources. They plotted access to the Boston markets through Maine's rivers and ports. By 1782, for example, Reuben Colburn from Pittston, the same Reuben Colburn who had built the leaky bateau for Benedict Arnold's ill-fated assault on Quebec City in 1775, joined with several others to explore northwestern Maine. On the top of their list was to see if it was possible to build a road from the headwaters of the Connecticut River to the Kennebec. Years later their efforts turned into the Coos Road, running from northern Vermont down the Androscoggin and Sandy River valleys to Hallowell.
A Revolutionary Was soldier, Col. Jonathan Holman of Sutton, Massachusetts, had heard reports and was spurred on to explore what would become the Town of Dixfield. He successfully raised a company of citizens from the Sutton area who also were interested in this enterprise. To a large extent, these men were from the same families who had fought with him during the French and Indian Wars in 1759 and again in putting down Shay's Rebellion just the year before.
Holmantown Memorial Plaque, Dixfield, 2003
Dixfield Historical Society
Col. Jonathan Holman, Deacon Asa Waters and Capt. Andrew Elliott, all of Sutton, Massachusetts, spent a considerable amount of time in August and September of 1787 in exploring land suitable to the establishment of a township. They could not, however, obtain the purchase of it until July 2, 1789, when Col. Holman "paid earnest toward it, for himself and others."
All were from Worcester County, Massachusetts and each paid his one, two or more 60ths of the costs. The price for the land which would become Dixfield was: 2,895 pounds, 11 shillings and 5 pence, plus expenses incurred of 136 pounds, 12 shillings and 5 pence. "The Early History of Dixfield" states that at one of the earliest town meetings held at Sutton, Massachusetts in April, 1791, the proprietors voted:
that four Rights shall be obliged to clear and seed 20 acres, set up a house
18 feet square, have 50 living apple trees on the land within six years from
the first of this month, or to forfeit to the Proprietary 50 acres on each Right.
Other directives were initiated and soon settlers began to arrive, forming three distinctive sections within Township No. 1 called Holmantown. They were Dixfield Common or Center, East Dixfield, and Dixfield Village. Upon its incorporation on June 21, 1803, these three sections grew into very diverse parts of the new community now called the Town of Dixfield. Each was a small community unto itself, but offering skills, talents, and spiritual brotherhood that benefitted their neighbors within the town as well as to those settling in nearby, newly established communities. With its incorporation, Dixfield became the 147th town in the State of Maine.


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I must object to this. Utah should be #1 thank you very much. Obviously, the makers of this list have not read Uprising USA.
I must object to this. Utah should be #1 thank you very much. Obviously, the makers of this list have not read Uprising USA.
Maybe it's the more moderate weather in Kentucky, George. We don't get much snowfall or seriously cold weather, and we tend to be reasonably damp the rest of the year.
Backlash for "nuking SLC" 😉
PS–I know it wasn't a "nuke"
Wouldn't the cold weather help against the zombies…freezing and all that?
"We've got some interesting news." The man in the white lab coat said.
I looked up from the receiver of my M-60 and put the oily rag down. "What is so interesting that you'd come all the way from London, still wearing your lab coat, when you could have sent a text?"
We were set up in a camp in the foot hills of some mountain I don't know the name of in Germany. We were on the way to Switzerland and we wanted everything to look clean and shiny and presentable.
The Swiss represented the only nation to survive almost completely intact from the uprising. Their borders have been closed since everything started. Neutrality has been enforced by armed barricades. Two days ago the message came that the Swiss wanted to talk to me, and cordially invited me to come visit. This meant only one thing. They wanted to trade.
Switzerland is not completely self sustaining. They have resources and agriculture… but they don't have enough agriculture for themselves, and they don't have the mineral resources. These things, they have to import.
We on the other hand, have a lot of agriculture and mining resources… but we lack something critical ourselves. Man Power. Most of Europe was dead, undead, or fighting to not become either of the others.
The man in the white coat was tall and bearded. I remember his face, but not his name. I had given him all the research we had taken from Cheyenne Mountain about the zombies. "I found it," he said.
"You found what, exactly?"
"The 3rd strain."
"Yes, we know there is a third strain… three bacterial and one viral… the Zombie Plague."
"Right, but we didn't know what the 3rd Strain did." The doctor wound himself up into lecture mode to tell me what I had broken into Cheyenne Mountain to get. I didn't stop him. "The first Strain converts proteins into sugars. Feeding tissues vital energy… when the zombie is stressed, the production goes into overdrive, giving the zombie that corpselike appearance even if the heart never stopped beating. The second strain of bacteria produces oxygen as a bi product, which is why zombies can't drown. They don't need to breath. The virus causes the brain damage that basically wipes a subjects mind of human behavior."
I was now impatient. "Yes, yes, we knew all of this… cut to the chase."
"Well, in all the studies, we could never find what the third strain did."
"Well the reason was because we never observed the strain under the right conditions." The doctor said with a voice that sounded as if that response would answer all the questions.
I tapped the machinegun with a .308 cartridges and raised an eyebrow.
"Well, we had taken a tissue sample and somehow it was put in the freezer."
"That's what activate the 3rd Strain!"
"Doctor… please…. for the love of all that is holy… I'm about to shoot you in the knees."
"Cold was the right condition!"
April was shaking her head. I pulled out my STI 10mm, "Tell me, right now… or I'm going to shoot you… What does the 3rd Strain do?"
"When they get cold, they produce Threitol and Sorbitol."
I put my gun down and sat back. "Ah… so when they get cold they produce alcohols… which act as an anti-freeze."
"Precisely," the doctor said. "This protects cellular walls in freezing temperatures."
I nodded, grasping this information. "Which is why zombies can freeze in the winter, and thaw out and revive in the spring… just like that beetle does."
The doctor looked puzzled. "Beetle?"
It was now my turn to lecture the doctor. "In Alaska there is a beetle that can freeze solid, but every spring when it warms up they revive and go about their little lives."
"Remarkable. I didn't know that."
I looked at him. "You didn't know that? I thought everyone did. Hmm."
"Well, the zombie plague has the same effect on the human body." He paused. "If this research could be put to use… we could prevent injuries from frostbite with an inoculation."
"That is the exact type of thinking that created the zombie plague in the first place. Doctor, listen to be carefully. What I want from you is a way to kill the zombies… Agent X works after awhile but in the mean time it makes the zombies a hundred times more dangerous until they finally die. Agent 11 and 12 works too slowly. We need something that works fast, without turning them into even worse monsters. That is the only research I want you to be doing. If you can't do that, you can help someplace else, like in one of the refineries, power plants, or fishing. You're choice. Now get out of my sight before I become irritated."
The doctor looked shocked and turned and walked out of the tent.
"A little harsh, don't you think?" April said quietly as she pulled a bore-snake through her ACR.
"Maybe." I stood up and walked to the tent flap and held it open. The doctor was stomping across the field, hands in fists. I picked up the mic from my lapel. "Caroline, do you see the man in the white lab coat walking west?"
After a second, "Yes, my Ogre, I see him."
"Tell him I said thank you and given him some food rations… make sure he has everything he needs."
"Roger that." Caroline said.
I turned my attention to the vehicles in the field. Men were scrubbing them with soap and water, cleaning off dried blood and mud. Even my Land Rover looked good now.
I looked back at April, she looked great but her uniform looked dusty from the long day of fighting through German towns. I looked down at myself. I looked about the same.
"Do we have any clean clothes at all?"
"Just some BDU's" She said, looking up at me.
"I think we need to go shopping. We need to look presentable when we go see the Swiss."
April grinned, "There was a nice store in Engen."
"Take the Girls and a team and see what you can find."
How do we get signed copies of all four?
Oh and Ogre ever get a chance to read "Recon of Worlds" on Amazon Kindle? Just asking cause I can't stand not knowing!!!
I'll look into the Recon of Worlds…
I'll do a Box set once my four are done.
Nice Uprising Europe teaser! Good work, George. I ordered my t-shirt yesterday!
FORTH?!! Alaska is fricken FORTH?
I read the comments about the map, the map maker based it on states with the highest number of gun sales in 2010. Screw that. we only have 600,000 people. I'm 100% sure there's enough guns in Alaska to arm every man, woman and child with at least two.
On top of that, there's only ONE ROAD into or out of Alaska. Heck, blow up two bridges and Anchorage would be cut off from the rest of the state. We pump oil, all the gas, diesel and JP used in-state is refined in state. All our electricity is generated in state, we're not connected to any grid that runs outside Alaska.
All of that and Kentucky is #1 in zombie survival. Well, when the real zombies come, I'll be glad to live here.
You will like Uprising USA then. Alaska becomes the R.O.A. Republic of Alaska.
Now you've given me a reason to read your book.
R.O.A. About fricken time!
Oh, and it's a frog we have that can freeze during the winter and come back to life in the spring.
National Geographic showed a beetle. Frog too? Interesting… but I used the biology base the bug had. Don't know anything about the frog.
Yeah, a frog is a step closer to people than a beetle is.
Don't worry Utah is #1. They use NICS data to proxy firearms in the state, BUT Kentucky runs NICS checks on CCW holders once a month, grossly inflating the NICS reports.
Ya but in the R.O.A. SaraP is the dictator in cheif, got to be a back story and fight there…you did not paint a very comfortable picture of the soccor mom in the Uprising USA story Og.
Ugh. Never mind my previous comment if you put that stupid $%*&* in charge again.
She gets something special before the series ends…
WTF?! West Virginia is #41?! That's ridiculous! Does NOT compute!
I'm trying to figure out how Arizona is at #25.
As usual, SC ranks low. So we're unemployed, dumb and can't survive zombies. Yay us!
Wyoming at # 40? 40? You've got to be joking. Casper would most likely fall, and maybe Cheyenne, but the rest of the state? No way. Infectable population centers would be few and far between. The maps base data is all wrong.
Utah at number 2? Maybe. But the Wasatch Front would be a friggin' WAR ZONE. If we're talking state wide data, this map is, pardon the language, all fucked up.
AHHHH taunting me with uprising I don't have in my hand! AHHHHHHHHHH!!!!!
UK is coming very soon…
P.S I loved Uprising USA if you didn't grasp that 😀


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Hear, Taste, Smell, See, Feel.
Last week you read about how to take a regular habit and turn it into an opportunity. Hopefully you had an opportunity to read on how important it is to reduce stress in your life and how you can use your breathe as a way to bring in the Rest and Digest mode. Then we brought it all together to changing a habit you already have so you can use it as a way to find moments of calm in your day.
Finding Pockets of Joy
Finding pockets of joy in your day can be difficult sometimes especially when your life is busy and you are overwhelmed with stress. It's annoying to have to think through how you would change something you already do in a way that would make life more enjoyable for you. It seems like the old way was working. Brushing your teeth was simply just to get your teeth clean and not a time to have to remember to do something else.
You have to be all in for it to work
None of this will work if you aren't able to see the benefit of taking time to stop being in fight or flight mode and bring yourself into rest and digest. You have no control over fight or flight. Rest and digest won't happen instinctually. For you to to have the balance between stress and calm you have to engage rest and digest to counteract your stress load. It's the only way. You have to take ownership of your ability rest in order to undo the physical reactions to stress.
Hopefully by now you have identified a habit you'd like to change but now you have a question on how to actually change it.
Use Your Senses to Guide You Through This Process.
Think of your habit and then ask yourself:
Can I focus on what I hear?
Is there water running that you can focus on?
Are there birds singing?
Can you focus on the sound of your breath?
What can you hear? Can you focus on that or at least notice it for a while?
Can I focus on taste?
If I am eating or drinking something can I focus on the taste?
Can I notice how my mouth, body and mind react to tasting this or even before I taste it?
What memories are tied to that taste?
As I taste it can I slow down and breathe so I can enjoy it more?
Can I focus on what I smell?
Focus on the smell of the hot cup of coffee you are drinking before taking a sip.
Linger with the cup by your nose and really smell what is in the cup.
Smell the flower, candle, cream you use while performing that habit.
Smell what you are eating so you can taste it even more.
Breathe in deeply so you can fully smell the item that is there.
Can I notice what I See?
What can you see?
What is the texture of the mug that holds your coffee?
What can you notice about the color of the wall in front of you?
Can you really see yourself in the mirror when you brush your teeth?
Can I identify what I can Feel?
What can you physically feel?
Is there a texture to your toothbrush?
Can you feel your clothing against your skin or the weight of your blanket in the morning?
How does the pencil feel against the paper when I doodle?
By just checking in with each one of the senses you can establish what would work while re-making your habit. Focusing on one or multiple senses while doing something and also focusing on deep breathing that you learned. You are well on your way to find pockets of joy throughout your day.
Just remember this is an exercise in slowing down.
Please don't try to see how many habits you can change at a time! Identify and change one habit and then once it happens automatically move on to creating the next one.


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Sign the Resolution
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Swedish National Road Administration, S-78187 Borlange, Sweden
In 1991, Sweden introduced requirements for drivers applying for licences after having been sentenced for having driven with more than 0.015 BAC (blood alcohol concentration). The driver is required to present to the licensing authority a certificate stating that he/she is not dependent upon alcohol or other drugs, this certificate can be obtained from a doctor but only after a minimum of three months observation. During this time, the applicant has to see the doctor on a number of occasions and liver enzyme testing will be applied. After this period - if no problems are found - the driver can obtain a conditioned license after passing the written and the practical driving test. The conditions last for at least 18 months during which he/she has to see the doctor at least three times to prove that a relapse has not occurred.
In order to study and evaluate the effects of the new requirement, the following data were collected in two counties:
The data was collected from 3754 cases in the two counties, June 1st, 1989 - May 31st, 1991 and June 1st, 1991 - May 31st, 1992.
The material was split into two sets:
A: in this set, action was taken after the revocation of the license.
B: in this set, no action was taken after the revocation of the license.
Set A was subdivided into eight subgroups in order to look at the proportion of licenses with specific conditions; the proportion of license applications, turned down and the reasons for this; the proportion of license applications with no administrative action and the reasons for this etc. Comparisons were made between before and after periods.
Set B was checked for presence in criminal registers. Those, who had no criminal convictions, were checked for drunkenness in public during the last two years. Comparisons were made between before and after periods.
In addition to the study of the cases, the administrative court doctors in all of Sweden and the doctors who had signed the certificates in one of the counties, responded to a questionnaire regarding the requirement and its effects. This questionnaire was answered by 19 of the 24 administrative court doctors and by 59 of the 80 certifying doctors.
The first issue concerns whether the proportion of applications turned down without administrative scrutiny had been influenced by the introduction of the new requirement.
Prior to the requirement 6.9% of the applications were turned down and after the introduction 4.6%.
Most of these cases are related to the fact that the applicants had been convicted again. Thus, some cases may be unrelated to the introduction of the requirement.
The propensity to supply the administrative court's request for additional certification was not changed by the introduction of the new requirement. Prior to as well as after the introduction, the proportion who failed to supply such certification was 11.6%.
The proportion of drunken drivers who chose not to reapply was 38.8% prior to the introduction and 21% after.
The general impression from the administrative court doctors is that they find the new requirement to have improved the quality of the process. Despite the fact that they cannot observe, directly, the treatment and rehabilitation given to the applicants by the certifying doctors, they have the impression that the new requirement has meant earlier treatment and more dependency treatment by specialists. About 50% of the administrative court doctors have experienced an increased work load.
As for the certifying doctors, they claim that they now write more comprehensive and stringent certificates. Treatment regimens have become more conform and stricter and the new requirements have made it easy to get the applicants to accept these new routines.
Some 60% of the administrative court doctors would like to see the BAC level, at which the new requirement takes effect, lowered from the present 0.15% down to 0.10%. Only 15% of the certifying doctors shared this view. However, 40% of them wanted the requirement to apply to all drunken drivers.
There had been some misgivings that the requirement would possibly mean that a greater proportion of drunken drivers, who had had their licenses revoked, would refrain from applying. The reason for this being that the new requirement would incur new costs for the applicants and also force them into treatment programs. Although the size of this study is limited, it indicates that these misgivings did not come true. Rather, we can see a tendency towards a smaller proportion of drunken drivers who fail to reapply for license.
We can also see that the doctors themselves and their patients, as indicated by the doctor, regard the new requirement as being beneficial.
We can find no contraindications relative to a lowering of the BAC limit, where the requirement takes effect, to 0.10%.


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Bauhaus - Museum Boijmans Van Beuningen
The curriculum at the Royal Academy of Art (KABK) in the Hague is in many aspects inspired by the Bauhaus. In the run-up to the exhibition The Netherlands < > Bauhaus - Pioneers of a New World at the Museum Boijmans Van Beuningen, students of the Interior Architecture & Furniture Design department received the assignment to create an interactive, stand-alone installation and a parade in line with the subtitle of the exhibition 'pioneers of a new world'.
Students were asked to delve into the Bauhaus: in its social context, in the content of the training and in the results achieved. This should form a historical basis for a contemporary interpretation of the two components of the assignment.
Pop-up installation and parade
Parts of the installation will be engaged in a choreography, forming a performance parading through the streets and resembling the Bauhaus Drachenfesten. The pop-up installation will be presented at various locations in Rotterdam, including the Centrale Bibliotheek (13-25 March) and the Grafisch Lyceum (26 March-25 April).
The research and the design process for the pop-up installation and the parade will be on view in Zaal G at the museum as from 9 February. The parade will hit the streets in Rotterdam on 9 and 18 February, 2 and 4 March.
KABK students receive a 50% discount at the Boijmans upon presentation of a valid student ID card.
Parade during the Museum Night in Rotterdam 2 March 2019
Parade photos by Sofia de Benedictes
Participating students
Iris Bossen, Sarah Bovelett, Joyce Edel, Rowan Graaf, Maple He, Aaron Kopp, Mabel Kraus, Bart Krijnen, Sasha Pirazhenka, Tijs Struijk, Daphne Veer.
Guiding teachers
Krijn Christiaansen and Cathelijne Montens
Guest teacher: Katleen Arthen
Project details
Museum Boijmans Van Beuningen
Type of work produced
research/design process, pop-up installation, parade


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Botanical Illustrations
The Grade 3 & 4 students were busy with observational illustrative artworks during their First Unit: How the world works. The unit of study examined p how plants and animals adapt to their environment in order to survive and to reproduce. The students had the opportunity to experiment and improve their drawing and painting skills using a trans disciplinary approach to the unit.
The students had time to practice their artistic skills on cacti, plastic eggs and pears, orchids, apples and strawberries. The students had the opportunity to use different art mediums including different kinds of pencils, pen, watercolor paints and pastels (with baby oil). In the drawing projects the students used different shading techniques to help make their illustrations more creative and give it a sense of 3-dimensionality to the different subjects. The students were very studious and brought their best in this special project. The classroom was specifically prepared for this shading project. The blinds had to be closed and the lights had to be shut down. Special adjustable lanterns were provided to give suitable lighting.
The students were very observant and focused on the forms of the chosen subjects. They successfully replicated their forms onto the paper. The students have shown that they were independent thinkers and inquirers. They were also risk-takers in embarking on this new challenge in art class.


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Continuous Flow Technology Partnership with Shanghai Desano Pharmaceuticals
Nov. 5, Shanghai – Asymchem and Shanghai Desano Pharmaceuticals Co., Ltd. signed a partnership agreement to commercialize continuous flow technology. Based on the agreement, Desano will leverage Asymchem's comprehensive knowledge of continuous flow reaction technology, including process development, quality assessment, equipment manufacturing, and quality attribute studies etc. that may be required in the registration process. Asymchem holds several patents in this area and this agreement is the first of its kind to realize the commercial cooperation model and reach the industrial application.
Asymchem hosts Forum on New China Policies within the Pharmaceutical industry
Nov. 5, Zhangjiang, Shanghai – Asymchem hosted the forum, Discussing the "Opportunities and Challenges of Innovative Pharmaceutical Industry Development under the New Policies". The forum invited top experts, scholars, key policy leaders, entrepreneurs, and investment leaders from within the industry in China. The forum allowed for discussion and interpretation of the future of innovative drugs from policy-driven high-quality development of China's pharmaceutical industry. As well as providing a platform for in-depth discussions on how to better promote the development of innovative drugs in China. During the forum, Asymchem signed cooperation agreements with Axtertx and UTC Therapeutics Inc and will provide continuous flow reaction technology services, CMC and clinical trials, mRNA-related assays, and other technology services to accelerate the process of innovative drug launch.
Five year anniversary of Shenzhen Stock Exchange IPO
From 2016-2021, Asymchem has had an impressive five-year post-IPO track record. As of today, Asymchem has 20 business centers, 8 production sites, and more than 7,000 employees, of which 2,600 are scientists and engineers worldwide. The company has had a compound growth rate of over 30% in operating revenue and over 30% in net profit. Over the past five years, Asymchem has maintained high R&D investment, and the four R&D technology platforms (CEPS, CFCT, CBST, and CIMT) have enabled Asymchem to continuously improve business capability. 617 projects have been completed since 2016, and Asymchem continues to contribute to global innovative drugs through its one-stop service platform. In addition, the company has also fulfilled social responsibility and contributed to sustainable development through various methods, such as Green Walk, the fight against COVID-19, and establishing scholarships.
Technology Updates
Transaminase mutant granted patent
Asymchem has developed its synthetic route for the preparation of key intermediates for migraine drugs utilizing the bioenzymatic method. Compared with the traditional chemical process of two-step reductive amination (high pressure, precious metal catalyst, 55% yield), the transaminase mutant obtained by enzyme engineering modification can catalyze the transamination reaction of the target substrate in one step with high efficiency (yield >81%, de >99.5%) and achieve kilogram-scale scale-up, showing great potential for industrial application. The related synthetic route and mutant sequence have been granted by the China National Intellectual Property Administration (CN112980810A, CN 112980899A ).
Oligonucleotide Service Platform Capacity Expansion
Asymchem has established a one-stop service platform for CMC of antisense oligonucleotides, siRNA, nucleic acid aptamer, vaccine adjuvant CpG, including process development, analytical method development and validation, GMP pilot production, process validation, etc. The company has achieved stable supply of oligonucleotide APIs and provided CMC services from phase I to phase III clinical and future commercializable production for several customers. Two pilot production lines have been established, which can achieve an annual production capacity of 10~16 Kg of siRNA. Asymchm will further enhance the capacity layout, it is expected that by 2022 4Q, 6~8 pilot production lines (60~100 Kg/year) and 2 commercial production lines (~200 Kg/year) can be realized, to reach the world's leading oligonucleotide API production capability.
500 L peptide Production Line Operational
Asymchem's commercial solid-phase peptide production line is now operational with two 500L solid-phase synthesis reactors, DAC600 purification equipment, and a 17.5m2 lyophilizer. The line can meet the demand of 5~10Kg/batch commercial production of peptides.


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Ethicheck are the proud suppliers of the MATOS® PLUS and MATOS® ARIA Pharmacy Grade Refrigerators, which are also referred to as Medical or Vaccine Refrigerators.
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PILE- 'Songs Known Together, Alone'
Pile are a rock band. They make rock music. Think Pixies or Polvo or Fugazi. Their last album was a winning combination of off-kilter rhythms, unique, unsettling quiets, and weird, wiry louds. But Pile began life as the solo project of singer-songwriter Rick Maguire. So, when the pandemic locked him and his band members in different places last year, it wasn't unprecedented that Pile pare down again. What's really come as a surprise though, is the end product of Maguire's isolation.
'Songs Known Together, Alone' finds the frontman picking through his band's entire back catalogue and revisiting, reflecting, and rewriting as he goes. In Maguire's own words, it is "a collection of re-imagined versions of songs from previously released records, tracked live and alone." In my own words, it is a smart, heartfelt, hypnotic effort, crackling with emotion and touched by magic. You might have heard these songs before, but you haven't heard them like this. These are old songs, but this is a whole new record. A stunning record. It has absolutely stopped me in my tracks.
The first half of the album is performed on guitar and some kind of foot-pedal synthesizer that might just be of Maguire's own invention- 'Touched by Comfort' (from 2015's 'You're Better Than This') is superbly slowed down while the circling, sparkling guitars some 90-seconds in lift me up, out of my chair and, thank god, out of my head. 'I Don't Want to Do This Anymore' (from 2017's 'A Hairshirt of Purpose') is extended from a sub-two-minute instrumental into a mesmerising, meandering, beautiful thing. And 'Keep the Last Light On' (from 2018's 'Odds and Ends') unhooks Maguire's voice from electric chords and lets it run loose through cloudy ambience. The second half of the album is performed on piano. 'Hair' (from 2019's 'Green and Gray') is a pretty faithful, but very pretty adaptation, while 'Build a Fire' (from 2007's 'Demonstration') has lovingly had all the lactic acid leeched out of its muscles. It stretches, it relaxes. And all of this was recorded live, in a barn in upstate New York, but it sounds neither loose nor far away. Instead, it sounds like Maguire could be playing in the very next room, and playing these songs the way they were always meant to be.
The tight, knotty nature of Pile's full band output can make me feel (in an admittedly compelling way) unsettled and tense. There is none of that here. Instead these 'Songs Known Together…' are subtle and tender and reassuring. Or maybe politely haunting. Either way, no amps are buzzing, no one is shouting. The hazy, constant quality of the synths makes me think of a comfort blanket, or of a safe space, or of sunsets, like the one on the front cover.
All that said, I don't think you need any familiarity with the original tracks for all of this to work. During the quietest spaces of 'Touched By Comfort' it's like being in a room while some natural born songwriter pulls a new tune out of thin air. You could play 'Mama's Lipstick' to… well, you can probably guess. And the way Maguire's voice, drenched in reverb, sometimes disappears into this music, would be compelling even if you'd never heard a rock band in your life. Sometimes it's not even a voice at all, it becomes a whole new instrument. On the newly-combined 'Rope's Length/My Employer' it initially sounds like Maguire is singing into a rotating fan, voice clipped and stuttering, before it disassembles completely, a robot chorus, static in the air. A whole new voice on a whole new record. Screw it, bring on more lockdowns, I want all my favourite bands to do this.


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Spartoo.co.uk - new voucher codes for July! Save up to 60%!
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Talk to one of our consultants today and learn how to start leveraging your business.
We answer by phone from Monday to Fridayfrom 9 am until 5 pm.
We will respond to your email within 3 hours on business days.
Visit on appointment Monday to Friday from 11 am to 4 pm.
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In the following extended excerpt from Wandering in Darkness Eleonore Stump provides a response to the overly dismissive critics of theodicy (and defense) (a theodicy seeks to explain why God allows suffering; a defense offers a possible explanation for why God allows suffering). The passage nicely marginalizes the incredulity of the critic even as it illustrates how such incredulity is of little persuasive force to the Christian:
"scornful disparagers of theodicy seem a bit like avuncular Martians whose sole knowledge of human life on earth comes just from videotape footage of medical treatments taking place within a large city hospital. Imagine how the doctors who run the hospital must look to such a Martian. The Martian sees patients being given drugs that make them sick and wretched. He sees patients having their limbs amputated or their internal organs cut out, and he hears the groans of those recovering from surgery. He sees patients dying in the hospital, including those dying as medical teams are doing things to them, and he observes the grief of their families and friends. This litany of misery could continue ad nauseum. The Martian seeing all this will be filled with horror and with moral indignation at the doctors who plainly allow the suffering when they are not in fact actively causing it.
"Any suggestion that the doctors are actually benevolent toward their patients will be met by the Martian with scorn and with incredulity that we would have the face to try advancing such a claim. The Martian knows what he has seen. We can try telling him that the patients are in the hospital in the first place only because they are sick, and he will reply indignantly that in very many cases there was no sign of sickness in them that he could see when they came into the hospital; the signs of sickness appeared only after the doctors went to work on them. We can explain to him that the sickness in question often take specialized skills, which only the doctors have, to diagnose; and he will dismiss our explanation with disdain as special pleading. We can tell him that without the treatments the patients would be sicker or would even die, and he will point out that many of the patients he saw died apparently just because of the doctors' treatments. We can respond that, on the contrary, many of the patients are in fact cured and live a long time outside the hospital, and then the Martian will turn on us with withering moral disgust at such pie-in-the-sky nonsense as the notion of life outside the hospital. And so on and on." (Wandering in Darkness, 17-18)
Given this illustration, I can understand why the Martian is skeptical, even disparaging, of attempts to explain the suffering of the patients. But of course, that doesn't provide a reason for us to be skeptical. We have a different perspective on the suffering than the Martian. We recognize the hospital as a place of healing and restoration.
In the same way that we embed the suffering in the hospital inside a larger narrative in which it is morally justified, so the Christian embeds the suffering of this life inside a larger narrative in which that suffering is morally justified.
The least we might expect from the Martian is the concession that from our perspective the sufferings of the hospital do not provide a reason to deny the goodness and/or capability of the physicians. Likewise, the least the Christian might expect from the atheist is the concession that from the Christian's perspective the sufferings of this life do not provide a reason to deny the goodness and/or capability of God.


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Onkyo will ship three THX-certified components in September 2010.
Onkyo will ship three new THX-certified components in September 2010, including its first multichannel preamp-processor that is also 3D-ready, a 150-watt nine-channel amplifier, and a next-generation Blu-ray player.
The flagship PR-SC5508 ($2,199) is a THX-Ultra 2 Plus certified, network-capable, 9.2-channel audio-video controller that is 3D-ready with an HDMI 1.4 interface. The PR-SC5508 also features:
-HQV Reon-VX video processing and 1080p upscaling
-ISF Video Calibration
-DLNA 1.5 and Windows 7 compatible connection to PC audio and Internet radio
-Pandora, Rhapsody, Mediafly, Slacker, Napster, VTuner, and Sirius Internet Radio
Connectivity on the PR-SC5508 includes 8 HDMI inputs, dual USBs, two balanced line-level XLR audio inputs, and nine XLR preamp outputs.
The matching PA-MC5500 ($1,699) nine-channel power amplifier is THX-Ultra2 Plus certified and is 8-ohm rated at 150 Watts per channel, and up to 400 Watts dynamic power into 3 ohms. It features Onkyo's WRAT (Wide Range Amplifier Technology) design for "low negative feedback, low distortion, extended frequency response, and a power supply with high instantaneous-current capability."
Other features of the PA-MC5500:
-A three-stage inverted Darlington circuit to remove distortion
-Balanced line-level XLR inputs
-Anti-resonant chassis and gold-plated inputs and outputs
-Multi-zone and bi-amp capability
The Onkyo BD-SP808 ($599) is a THX- and DLNA 1.5-certified Blu-ray player that offers Blockbuster On Demand, Marvel Qdeo video scaler and Dolby TrueHD and DTS-HD Master Audio sound.
The Profile 2.0 BD-SP808 has an Ethernet port for BD-Live features, including picture-in-picture and web-based firmware updates. There's an SD card slot for playback of downloaded web content, and HDMI Source Direct mode outputs video signals in their native resolution.
by Steve Crowe
Custom Installation Services, LLC – "We may be a few dollars more than the competition, but we are a million times better".


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On Wednesday, October 10, 2018, the City invites the community to City Hall to participate in a meeting to establish a vision and conceptual plan for downtown Napa's Brown Street Corridor. The focus area for the project includes the segment of Brown Street between Pearl and Third Streets. Revising the vision for this space could allow for more recreational space for families to gather, as well as employees from local businesses to enjoy during their workday. Additionally, new potential plans could allow for more walkable and bike-able space right in our downtown, tying the north and south ends together.
While several sites along the corridor promise opportunities for future private redevelopment, the City is proactively attempting to identify and establish a community vision so future development proposals can be responsive to that vision.
As part of the project, the City will be examining the function and flow of movement within the corridor, and the downtown. As part of the study, the City is considering different phases of development for the project. For example, engineers are in the process of analyzing the Second Street Garage to determine the structural feasibility of retrofitting the garage to accommodate a more pedestrian-focused design (between First and Second Street). Long-term plans could consider completely replacing the garage as part of a future redevelopment plan. Designers are also considering a pedestrian-focus for Brown Street, between Second and Third Streets.
To date, stakeholder interviews with local property owners, businesses, non-profits, and other government organizations have established that a pedestrian and bike-friendly design could enhance the overall downtown in many ways – from a transportation connectivity standpoint to outdoor recreational and dining opportunities, as well as enhanced greening along the corridor. Earlier this summer, the Parks, Recreation, and Tree Advisory Commission, an advisory body to the City Council,gave input on the project. All of this input has set the stage for the October 10th Community Meeting.
Community members can elect to attend a short presentation by the design consultant at either 6 p.m. or 7 p.m. After the presentation, attendees will be invited to participate in a 40 to 45-minute interactive session, wherein they can indicate their preferences for specific design elements.
Funding for the conceptual design project was made possible by a federal grant the City received through Caltrans. These funds are enabling the City to begin the visioning process for the corridor concurrent to completing the corridor's primary civic space, Dwight Murray Plaza. City staff anticipates completing the design by the end of the year.
Check out the flyer here!


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A month ago, I looked at the month of April for the Red Sox. That worked well, so we're doing it again.
In general, May was good to the Red Sox. They went 15-11 — a step back from their torrid April, but still good — and finished the month in second place in the AL East behind the red-hot Tampa Bay Rays.
Some things went well for the Red Sox, as they were anchored once more by a strong showing from their offense. The unit finished 7th in baseball in wRC+ for the month. Still, many things took a step back as well, including their rotation, which had the 11th worst ERA in baseball, and their bullpen also took a step back, going from the 7th best bullpen ERA to the 16th best.
The offense being a strong point is no surprise, but what was surprising was where they were getting their output from this month. Hunter Renfroe had an incredibly hot May, as he carried more than his share offensively over the past month. Batting .319/.333/.604 for the month of May, Renfroe finished the month with the second-best wRC+ (155) on the team, trailing only Xander Bogaerts and finishing a spot ahead of Rafael Devers.
One more impressive performance offensively in the month of May belongs to none other than Enrique Hernández. Following a right hamstring strain and a subsequent rehab appearance in Worcester, his bat returning to the lineup gave the Red Sox a bit of a shot in the arm before falling off a bit at the end of the month. In all, he hit .255/.328/.400, acceptable for a leadoff hitter. While I was skeptical about his ability to play leadoff, given poor on-base skills in the past, he has recovered from a substandard April to become a solid overall contributor in this Red Sox lineup.
But it was not all sunshine and rainbows. Several players underperformed in May as well. The first player of note was Franchy Cordero, who has already been demoted to Triple-A Worcester to work on his swing in a low-stress environment. Cordero has been a frustrating player to watch, in part because his talent level should be higher than he is showing. Prior to his demotion, he launched a ball several millions of feet away, probably into the stratosphere (OK, so it was only 474 feet), which gave Sox fans a great parting gift. Currently in Triple-A, he's been hitting bombs, something I expect to continue.
I was also put off by the performances of Marwin Gonzalez and Bobby Dalbec. Christian Vázquez escapes my ire on the basis of being extremely good defensively, and being only a bit below average offensively for the month of May.
Gonzalez's defense has actually been pretty good, especially for a utility player, but his bat has been black hole level terrible for the past month. Part of this is aided by a terrible 2.5 percent walk rate (he drew only one more walk than Nate Eovaldi, a pitcher, despite playing in 21 games) and 30.4 percent strikeout rate. He's been borderline unplayable, only slipping through the cracks because the rest of the team has been hitting well enough.
Dalbec in particular has me already looking at potential first base options that could be available via trade over the next two months. His hitting has been bad, and his defense has been worse. At first base, we just have a higher level of expectation from our players at the plate and Dalbec, for as much power as he possesses, is just not reaching that level. He hit .200/.243/.429 for the month of May, with his wRC+ coming in at 80 (100 being league average).
While the pitching took a step back after what was a masterful month of April, there were some bright spots to be had, and you don't have to look that far to find the first star of the month in Josh Taylor. Taylor had become something of a whipping boy for armchair general managers and fans across social media, but the lefty's performance should silence his critics. Taylor came into 11 games in the month of May, pitching eight scoreless innings in the month. He was often called in with runners on, and some scored, but this is less a Taylor problem and more a problem for whoever he relieved.
Hirokazu Sawamura also had a particularly good month, as he pitched to a 2.16 ERA himself in 8 1⁄3 innings of work. While he was still quite hittable, he limited the damage allowed in part due to his only allowing two walks for the month. More impressively, he struck out fourteen batters in his small sample of innings and did a good job of throwing strikes in general (66 percent for the month).
Other relievers at the upper end of the hierarchy did well, such as Adam Ottavino, Matt Barnes, and Darwinzon Hernandez, but this almost doesn't merit mention as they performed to expectations. Hernandez was bit a touch by the walk bug, Barnes had a single shaky outing, and Ottavino played his wire to wire tightrope act well, and none of this is shocking to me.
The last positive mention I want to make here is for Martín Pérez. He performed greatly in the month of May, just as he performed acceptably in the month of April. This is great for the team, as the relief corps have been a bit inconsistent. For Perez to come in and do his job is great. He is pitching well above expectations, and one can only hope that continues.
However, I'm not sure which Pérez we will get in the second half of the season. He has performed well in the first halves of seasons in the past, but I wanted to look more deeply into it. Pérez has had three full seasons of note in 2016, 2017 and 2019. In 2016, his ERA through May 3.12. After May it was 5.03. In 2017, his ERA through May was 4.19. After May it was 5.14. In 2019 he had a 3.71 ERA through May, but a 5.93 ERA after. Will this happen to Perez again in 2021? I hope not, but it bears watching going forward.
There were a few bad performances that need to turn around if the Red Sox want to have a successful June. The chief offender this month has to be Eduardo Rodriguez. After a strong April that made many of us think he was back following COVID-related myocarditis, May definitely has given me pause on this assertion. While he has been hamstrung by some bad luck, the general quality of contact against him has also been stronger, which makes me think it isn't luck, but rather an issue with decreased velocity and poor pitch selection or sequencing. We cannot eliminate the possibility he is tipping his pitches, either. Either way, his ERA ballooned to 7.28, easily the worst month of his career.
For all the good things I wrote about Matt Andriese last month, I have to write some pretty bad things this time around, as he was wholly ineffective and thrown into situations that didn't make a whole lot of sense. I'm not sure what Andriese's role is with the Red Sox going forward, but I certainly hope more care is given to his placement in the coming months. Part of this can be fixed by having the starters pitch deeper into games, as five of his nine appearances began in the sixth inning.
The last negative note for the month will be the combined form of Austin Brice and Colten Brewer. Brice was designated for assignment to clear a roster spot for Danny Santana. He went unclaimed on waivers and still lurking in the organization. Brewer didn't pitch as much as Brice, but showed he was (so far) the same Brewer as before, as he gave up four hits, three walks, and four earned runs in a single inning of work, taking a potentially winnable game and pushing it so far out of reach that Alex Cora brought out bench players to rest his starters.
It was a good month for Red Sox baseball, but one that also showed this team needs a lot of improvement if it wants to hang in the playoff discussion this season.
A: Xander Bogaerts, Rafael Devers, Hunter Renfroe, Josh Taylor, Hirokazu Sawamura, Martín Pérez, Matt Barnes
B: Danny Santana, Kevin Plawecki, Enrique Hernandez, J.D. Martinez, Alex Verdugo, Eduard Bazardo, Adam Ottavino, Darwinzon Hernandez, Garrett Richards
C: Jonathan Araúz, Michael Chavis, Christian Vazquez, Garrett Whitlock, Nathan Eovaldi, Nick Pivetta,
D: Bobby Dalbec, Christian Arroyo, Phillips Valdez
F: Marwin Gonzalez, Franchy Cordero, Eduardo Rodriguez, Matt Andriese, Austin Brice, Colten Brewer
On the whole, the team performed well, and several players played up to expectations at the least, so I would give the team for the month of May a B. They played better in April, and against a lot more divisional opponents. Many of this month's games were against non-divisional opponents, which may be a saving grace in the long game. In June they are up against a gauntlet of teams, playing the Astros six times, the Yankees six times, the Blue Jays four times, and the Rays three times, with only two off days the entire month.
Month Ahead
Three players I'm highlighting for the month of June: Garrett Whitlock, Nick Pivetta, and Eduardo Rodriguez, as I see them as the keys to potential success over the next month. Which Whitlock are we getting the rest of the way? He was excellent in April and merely acceptable in May. Is Eddie going to be a problem we need to solve later this year? Was May a mirage or a sign of ailments bothering him? Can Pivetta chill out with the base hits? He lowered his walk rate a lot, and he feels so close to figuring something out.