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Fire Safety Training
In accordance with Article 21 of the Regulatory Reform (Fire Safety) Order 2005, the College provides training on various fire safety topics to complement the physical safeguards that are in place within our buildings. The following courses are available to staff and can be booked online:
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The new 2021 Mercedes-AMG GLS 63
The apex of performance Disclaimer[1]
The apex of performance: Discover the new 2021 Mercedes-AMG GLS 63 SUV.
The Mercedes-AMG GLS 63 SUV is the S-Class of SUVs with an extra boost of power.
Summiting the peak of power comes the new 2021 Mercedes-AMG GLS 63 SUV.
Satisfying a hunger for intense performance, undeniable comfort and dynamic agility comes the latest in advanced sport utility vehicles. This stunning specimen knows the meaning of expressive elegance while dominating the blacktop with an imposing design. Its AMG-specific radiator grille with vertical slats in high-gloss chrome is our largest yet. Reinforcing its domineering stance, this SUV features standard Active LED Headlamps with Adaptive High Beam Assist and a silhouette amplified by the newly designed front bumper with an integrated jetwing.
Step inside to experience a cavernous interior thanks to its increased wheelbase, lengthening legroom exponentially. Claiming the prestige as the S-Class of SUVs, the GLS 63 delivers first-class comfort with AMG driver and front passenger seating that provides lateral support with AMG-specific upholstery. Optimal comfort includes multicontour seats with climate controls and massage functions. Additionally, a top-tier visual presence demands the same of its soundscape — and the Burmester® surround sound system delivers just that. And when intuition is in need, the Mercedes-Benz User Experience (MBUX) multimedia system is awaiting your every whim. Simply state "Hey Mercedes" to activate numerous functions via this natural voice technology further connecting you to your vehicle.
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The Mercedes-AMG GLS 63 SUV is set to take on the pavement summer 2020.Disclaimer[1]


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After a week of dramatic shifts and major pivot points, it's time to make a few adjustments.
As the planet of love, abundance and self-worth glides through her last week in the sign of the scales, she'll be confronted by the three outer planets in Capricorn, during which time we will all be forced to ask ourselves: 'Do the books balance?,' in all senses of the word.
A series of squares between Pluto, Jupiter & Saturn, and Venus in Libra will also be asking you to reassess personal values, boundaries and power dynamics within key financial or creative situations and close relationships to make sure that everything is fair, just and equitable.
Is there mutual reciprocity? Do you feel valued by others, and vice versa? Do you still share the same core beliefs and values? Do you want the same things? Or are you now on different pages from some people in your life?
The good news is that as this happens, the Sun, fresh from its conjunction at New Moon, will form positive aspects to both Jupiter and Saturn, helping to counteract any potential doubts or feelings of alienation, self-pity or unworthiness with a dose of calm confidence and inner conviction – suggesting that you will intuitively know the answers to these questions by the way you feel inside, particularly in your heart and solar plexus.
Do you feel as if you are coming into greater alignment with your sense of personal truth, integrity and self-respect? If so, then take this as your guide and compass. Know too, that while some connections may now naturally fade into the background, others are likely to grow, strengthen and in some cases, new connections may also start to come in for you, particularly once we move into Sagittarius season, which happens at the end of the week. This is the Law of Resonance.
Surprise news, shocking plot twists and abrupt endings related to travel, communication and technology could also occur on Tuesday as Mercury opposes Uranus. You'll need to employ a lot of patience and tact to avoid stubborn stand-offs or mental tussles. Expect possible tension or anxiety levels to temporarily spike as you adjust to sudden surges of electrical activity or incoming information from unexpected sources within your mental body or upper chakras.
To find out more about what to expect from the Cosmic Weather this week, check out my videocast on IGTV.


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WHO: 2020 - the year we understood the true value of health
Baku, January 15, AZERTAC
"The COVID-19 pandemic has shaken the world and brought many countries to a standstill. The virus has swept through our nations, communities and lives, exploiting gaps in our emergency preparedness, weaknesses in our health systems and inequalities in our societies. It is a human tragedy and a global crisis. As we have stepped into 2021, we look back to 2020 what have we learned, what have we achieved, and what hope is on the horizon?" says an article by representative of the World Health Organization (WHO) in Azerbaijan, Dr. Hande Harmanci and WHO Regional Director for Europe, Dr. Hans Henri P. Kluge headlined "2020: The year we understood the true value of health".
A Year in Review: Lessons learned
Experience has now shown us that health is at the centre of development, a determinant of individual and collective growth. At every step of life's journey, we need targeted, tailored support to promote our health and well-being. Attending school is precious for a child's social development; providing a social safety net is vital when jobs are threatened; creating supportive environments and quality care offers older people the dignity they deserve.
Responding to the pandemic has required action beyond treating the virus. Insights into human behaviour and cultural norms have been critical to tackle COVID fatigue and misinformation campaigns spread through social media. We have learnt that we needed to engage communities more effectively to be part of the solutions. And that only when measures are scientifically sound and culturally acceptable will they be effective.
To meet varied and complex needs, health systems have had to adjust with unprecedented speed. They established dual track service delivery where essential services were provided in parallel to services focused on pandemic response. Digital solutions have contributed to bridging service gaps when face-to-face services were impossible. These innovations will be crucial to catch-up for missed heart disease, diabetes, hypertension, cancer and other disease-specific services, and to accommodate growing mental health needs.
Science and research have been indispensable in shaping our response – from developing diagnostics, exploring treatment and producing vaccines at unprecedented speed. Old and new technologies have been used to establish the evidence for public health and social measures.
Our health and care workers are cherished professionals, who deserve our unwavering respect and gratitude. They also require adequate social, mental, physical and financial support, to ensure their health and well-being, and to guarantee sustainable, functioning health systems during the pandemic response and beyond. Frontline workers – teachers, social, community and postal workers, bus drivers, grocery and supermarket staff, and many others – who before were invisible and undervalued, have kept our societies running.
We have seen inspiring examples of community solidarity, human ingenuity, collective and individual compassion in every corner of the Region. People have remarkable resilience, optimism and generosity and Azerbaijan was no exception.
The WHO Country Office in Azerbaijan has been at the epicentre of the COVID-19 response in the country since the beginning, supporting various ministries, government partners, agencies, and NGOs. We have also been one of the major sources of information for the UN at large, the diplomatic community and international partners.
WHO was one of the "early responders" in the country, bringing in international technical expertise, physically and virtually, to prepare the health system for the upcoming surge. The REACT-C19 project, which started in April 2020, was a quick response to help prepare hospitals for the pandemic. At that time, when there were 6 COVID designated hospitals in the country, REACT-C19 teams worked in 12 hospitals over a period of 3 months to improve their readiness to accept COVID patients, as well as create a safe environment for health care workers and patients. REACT-C19 has left a legacy, the PROACT Project, which aims to support the creation of sustainable systems to improve the essential competencies of health care workers and to deliver essential health services to those who are left behind because of COVID-19.
In addition to technical assistance, Azerbaijan has also received WHO laboratory testing kits, large numbers of personal protective equipment, and hospital equipment from WHO to improve the management of COVID-19 patients. We are grateful to have collaborated with the main development partners in the country, the European Union and USAID, to provide both technical assistance in Azerbaijan as well as life-saving devices and goods.
The recent hostilities in and around the Nagorno-Karabakh region significantly stretched the health system, which was already under stress due to the pandemic. Numbers of new cases and deaths increased rapidly during the time. This had a knock-on negative impact on the provision of essential health services such as vaccinations, control of some chronic diseases, etc. Findings from a WHO-organized health needs assessment mission in Ganja, Barda, Tartar and Aghdam highlighted areas for further collaboration and where health services should be strengthened. We will be honoured to support with the Government of Azerbaijan in these areas and beyond.
Furthermore, we were extremely proud when Azerbaijan allocated a total of $10 million to the WHO central COVID fund to fight the pandemic, showing solidarity with the global community. This has given the WHO Country Office in Azerbaijan a boost and encourages us to do even better for the health of the country.
The year 2020 has shown us that health is not only an individual concern, but it requires collective effort.
2021 and beyond: leaving no-one behind
We all have a role to play to shape the future we need. This can only be achieved by placing health and equity at the heart of all policies. WHO/Europe's health strategy "United Action for Better Health", is built upon what citizens expect from their health authorities in order to thrive in healthy communities. For this, we need to guarantee people's right to universal access to quality care, accelerate action to reduce health inequities and strengthen public health leadership at local, regional, national and international levels. This is an ambitious agenda but one we can achieve together. People increasingly – and rightly – hold their health authorities to account for meeting these expectations and to "leave no-one behind."
In the wake of COVID-19, it is clear that building strong, sustainable, equitable and responsive health systems is in everybody's interest. Health is fundamental to ensure both economic development and social cohesion.
There is a wider context to health – from how we produce our food, the way we live in urban settings, the factors that make communities resilient, to what areas our financial systems invest in, and the value we place on those who provide essential services. The pandemic has forced us recognize and reassess these issues.
To lead us in a new direction, WHO/Europe has brought together expert and political voices. The Pan-European Commission on Health and Sustainable Development comprises experts from a range of fields including former heads of state and government, distinguished life scientists and economists, heads of health and social care institutions, and leaders of the business community and financial institutions. The Commission is looking forwards, through the impact of the pandemic, to changes that are needed in society, with a view to elevating health to the top of the political agenda. It will offer guidance on how to invest in health, health systems and social care systems for the benefit of all sectors.
2020 has taught us that health is not something we can take for granted, and healthcare is only truly effective and protective if everyone has access. If we want to protect ourselves from future crises, we must leave no one behind.


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Visitors are spoiled for choice, with a range of attractions from museums and galleries, markets, sports, desert safaris by the spectacular Inland Sea or the UNESCO-listed Al Zubarah Fort.
In the morning, take some time to walk along the Corniche and enjoy the architectural diversity of old and new Doha by day.
Visit the Museum of Islamic Art (MIA). The MIA's magnificent and imaginatively presented displays of the finest art and artifacts from across the Islamic world have earned it recognition among the world's top cultural institutions.
Spend your late afternoon wandering through the bustling alleys of Souq Waqif for an authentic experience taste of traditional commerce, architecture and culture.
Start your day by getting your adrenaline rush with a heart-stopping roller coaster ride over the desert steep dunes. Many tour operators offer a range of activities from a 4x4 off-road safari to camel riding, sand boarding and driving a dune buggy.
Most of the desert tours will take you to Qatar's most impressive natural wonders, the 'Inland Sea' or Khor Al Adaid. A world recognized natural reserve with its own eco-system. This is one of the few places on earth where the sea encroaches deep into the heart of the desert.
For those in search of chic luxury and high-end shopping, The Pearl-Qatar is a man- made island off the West Bay coast featuring Mediterranean-style yacht-lined marinas, residential towers, villas and hotels, as well as brand name boutiques and showrooms. When you get hungry there are plenty of dining options, the waterfront promenades are lined with cafes and restaurants serving delicious local and international cuisine.
Next visit the Sheikh Faisal Private Museum at Al Samriya featuring a fascinating collection of more than 15,000 exhibits covering a spectrum of arts, artifacts and equipment. You can also see many everyday household and traditional items that evoke a flavor of Qatari life in the pre-oil era. A highlight for most people at this museum is its extensive collection of vintage cars.
If you want to learn more about the history of Qatar then check out the Al Zubarah Fort. Located on Qatar's north-west coast and surrounding 60-hectare archaeological works, this UNESCO World Heritage site is one of the most extensive and best-preserved examples of an 18th–19th century settlement in the region. It covers the remains of a walled coastal town that once ranked as one of the Gulf's most important pearl diving and trading centers with links extending to the Indian Ocean. The fort houses a visitor centre.
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The Houston Astros will look to stop a nine game losing streak as they start a four-game series Thursday night against the Pittsburgh Pirates at Minute Maid Park.
The Pirates start the series just 2-1/2 games behind the Cincinnati Reds while sitting in the first of the two National League Wild Card spots. The Astros are currently last in the Central, 24-1/2 games behind the Reds.
Houston will send out rookie left-hander Dallas Keuchel (1-2, 4.03 ERA) to the mound, making his second start after being recalled from Triple A Oklahoma City. In his last start against the Arizona Diamondbacks on July 21, Keuchel was roughed up for seven hits and six runs in just 3-1/3 innings in Houston's 12-3 loss.
The Pirates will counter with A.J. Burnett (11-3, 3.59 ERA), who has thrived after being traded by the New York Yankees in the offseason. In his last start against the Miami Marlins on July 21, Burnett earned the win after giving up eight hits and one run in 7-1/3 innings in Pittsburgh's 5-1 win.
Check out the game schedule and broadcast information right here:
Date/Time: Thursday, July 26, 7:05 p.m. CT
TV: Fox Sports Houston
Online streaming: MLB.tv
Read more on the Astros at The Crawfish Boxes and SB Nation Houston. Head over to Bucs Dugout for more on the Pirates. Baseball Nation is your source for news and analysis around Major League Baseball. Also, be sure to subscribe to the SB Nation Youtube Channel for video commentary.


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However and can, although rarely, reach and damage the central nervous system, especially during fetal development. In areas hard hit by the 2015-2016 South American epidemic, there has been an unusual increase in cases of neonatal neurological abnormalities and Guillain-Barré syndrome (GBS).
This simple observation, supported by scientific evidence, prompted the WHO to conclude that ZIKV infections contracted during pregnancy are a cause of congenital brain abnormalities and that ZIKV is a trigger of GBS.
In fact, it has been observed that congenital ZIKV infection can be associated with a wide range of brain abnormalities, including microcephaly, craniofacial disproportion, intracranial calcifications, brain atrophy and asymmetry, abnormal or absent brain structure, hydrocephalus, migration disorders neurons.
The following neurological problems have also been reported: hypertonia, spasticity, hyperreflexia, irritability, tremors, convulsions, brain stem dysfunction, limb contractures and dysphagia. Concerning the eye, the following problems have been reported: microphthalmia, lens subluxation, cataract, intraocular calcifications, optic nerve atrophy, optic nerve hypoplasia, macular degeneration, macular chorioretinitis, chorioretinal atrophy.
Other neonatal abnormalities that have been reported include: excessive and redundant scalp, arthrogryposis (joint stiffness) and talismus (flexion of the foot that rests only on the heel).
Obviously, congenital microcephaly and other neonatal abnormalities can also have other causes, including genetic disorders (chromosomal abnormalities), craniosynostosis, cerebral anoxia, exposure of the mother during pregnancy to factors such as alcohol, mercury, radiation, severe malnutrition or other infections ( such as cytomegalovirus, herpes simplex, rubella, lymphocytic choriomeningitis, chicken pox, syphilis and toxoplasmosis).
The virus generally remains in the patient's blood (viraemia) for up to 14 days after the onset of symptoms (although there have been cases of much longer viraemia), during which time if it is bitten by a competent mosquito (eg tiger mosquito) , the disease can be spread.
There is currently no vaccine or specific treatment for ZIKV infection or associated diseases.Treatment is symptomatic and mainly based on pain relieving, antipyretic and antihistamine therapy to reduce itching caused by skin rash. In addition, bed rest and fluid replenishment are recommended.
The only way to prevent infection is to avoid being bitten by an infected vector (mosquito). Residents or travelers in a country, where the virus is present, must take protective measures by covering exposed skin with appropriate clothing
(long sleeves and long pants) especially during the hours in which the vector circulates (being daytime mosquitoes, from dawn at sunset), use repellents, adopt physical barriers (mosquito nets on doors and windows) and stay overnight in places protected by mosquito nets.
For the possible serious consequences of an infection contracted during pregnancy, special precautions must be taken by all couples who intend to have a child and pregnant women who live or travel to countries at risk. In particular, those who have traveled to these countries should not have unprotected intercourse on their return for at least 3 months for men and 2 months for women.
Those who live in areas at risk and are planning a pregnancy must instead do everything possible to avoid exposing themselves to the bites of infected mosquitoes. More information can be found on the WHO website (see MORE INFORMATION at the bottom of the page).In countries where the virus is not present, the basis for a good response in case of accidental introduction is surveillance.


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Whatever small appliance you're looking for, you've come to the right place. We stock loads of food processors, kettles, toasters, coffee machines and more.
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You can check out our different small appliance buying guides here.


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The Suites at our 3 star hotel in Kochi are designed keeping in mind the tastes and preferences of the modern traveller. These suite rooms in Kochi have an area of 495 sq. ft. and can accommodate 2 adults and 2 children comfortably. Our suites in Kochi offer the perfect sojourn when you are travelling with friends and family. The suites come with a separate living room, where you can unwind after a long day and have a relaxing stay in Kochi. Additionally, we also offer amenities like 24-hour room service, high-speed Wi-Fi, tea & coffee maker, mini bar, wardrobe and much more to help you have a comfortable stay at one of the best hotels in Kochi.
- Air Conditioning
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Authentic Writing
Since 1993
Good writing is art. It has a life of its own. Authentic Writing creates a studio where every writer can discover and explore their most important stories, a place to become the writer that only they can be.
Marta Szabo, co-director and facilitator
Fred Poole, founder and co-director


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before encore 6 a collection of portraits by john lee bird
14 Jun 2016 – 15 Jun 2016
Event times
Tuesday: 18:00-23:00
Wednesday: 12:00-23:00
Cost of entry
20th Century Theatre
- 291 Westbourne Grove
- Notting Hill
- London
- United Kingdom
John Lee Bird marks ten years of before encore project with exhibition of 36 new portraits documenting London's mercurial creative counter-culture at 20th Century Theatre
before encore is an ongoing portraiture project in which seminal London artist John Lee Bird documents the influential performers, muses, designers, musicians, poets and artists who exist within the creative spaces between marginal and mainstream popular culture.
2016 sees before encore enter its tenth year and 14th-15th June sees a two day exhibition at London's 20th Century Theatre of the latest 36 portraits representing a diverse subculture of London's performance/club/queer/music DIY art scenes.
The exhibition will be a riotous celebration of not only John Lee Bird's work but also his subjects, with countless musicians & performers from the latest portraits taking the stage, as well as a number of surprise guests from previous phases of Before Encore.
The exhibition, which is free and unticketed, runs from 6pm-11pm on Tuesday 14th June & from 12pm-11pm on Wednesday 15th with live performances from 7pm on both nights. Musicians & artists confirmed to perform include Madam, Mikkokoo, The Black Site, Catmilk, Chicken, Sam Amant, Bete Noire, Campbell L Sangster, Thom Shaw, Dale Cornish, Marisa Carnesky, The Budda Cakes, Mr Teds, Timberlina & Oozing Gloop as well as a number of surprise guest appearances.


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We might be further away from conducting secure, online elections than most people realize, according to a new report.
Designing and implementing a reliable and accountable online voting system is extremely complicated because of a wide range of security flaws, inaccurate authentication measures, and a lack of publicly reviewed standards, experts have concluded.
In a report commissioned by the U.S. Vote Foundation, an organization that provides absentee ballot and voter-registration services, researchers noted that "every publicly audited, commercial Internet voting system to date is fundamentally insecure."
"Until researchers adequately address these challenges, Internet voting systems should not be used in public elections."
The research team, comprised of computer-science experts from more than half a dozen American universities, concluded that for any online election system to be viable, it must be "end-to-end verifiable." The end-to-end verification system, or E2E, would enable users to ensure that their votes have been correctly recorded and included in the final tally. For the sake of transparency, the researchers said, the process must also let voters "check for themselves that the election result is correct and the election was conducted properly."
It remains unclear, however, whether it is currently possible to meet the rigorous standards set forth in the report.
For instance, there are additional problems that cannot be solved by simply implementing a reliable end-to-end verification system. Experts note that an online voting system may still be vulnerable to denial-of-service attacks that aim to disrupt large numbers of voters.
A system that is correct, secure, and usable is still not useful to voters if it is unavailable during an election. Many government websites are unreliable, especially during a distributed denial-of-service (DDoS) attack or just after a security breach.
Many companies whose businesses depend on having highly available and secure websites have effectively solved this problem. Companies like Amazon, Google, and Facebook have uptimes comparable to those necessary to run a public election, even if threatened by DDoS attacks.
The necessary network, server, and security infrastructure—and the consequent cost—to fulfill the availability demands of these companies and their customers is significant. The cost is so significant that every government that has attempted to build a facility dedicated to running Internet elections has spent many millions of dollars per election.
The widespread use of malware is also a major concern. "A compromised computer may corrupt the voting phase: even if the voter receives an unaltered ballot, malware may change the way the ballot is displayed or the way the vote is recorded before casting the ballot," the report said.
Another hurdle to implementing an online election system is authenticating voters. As the researchers observed, the system must be able to positively identify the voter in a way that is impossible to counterfeit.
"Unfortunately, [authentication] is a very difficult and complex problem that remains unresolved (in the U.S. at least) for the foreseeable future," the report said.
As the integrity of the vote is a matter of national security, common authentication methods such as passwords or email confirmations would not suffice.
"Almost every month we hear of huge data breaches at commercial or government institutions that have already allowed vast amounts of personal information on tens of millions of people to fall into the hands of criminals or foreign powers," the report noted. "Thus, any authentication mechanisms based on merely presenting personal information (name, address, account number, driver's license or social security number, mother's maiden name, etc.) [are] hopelessly compromised already, and way too weak for use in an election."
Moreover, the report's authors said, the research community must figure out how to setup an online voting system that average voters can understand. "Most voters are not system administration experts," the report said. Experts must also determine how to avoid new forms of voter fraud that may arise in the context of online elections.
"While some of these issues can be addressed by current technologies, further research is necessary to determine if all of these concerns can be adequately addressed, " the report concluded. "Until researchers adequately address these challenges, Internet voting systems should not be used in public elections."
Illustration by Max Fleishman


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is a form of exercise which requires total body resistence.This type of training will increase your strength, core stability and functionality! It will improve your fitness levels for athletic performance and a better everyday life!
HIIT or METABOLIC TRAINING
is the current rage in fitness, fusing High Intensity Intervals with total body weight exercises, torching calories before and after your workout! This workout is perfect for the modern overscheduled trainee, increasing strength, improving cardiovascular capacity, burning fat, building muscle and boosting metabolism, all in 30 min or less!ENDURANCE TRAINING
trains the aerobic system, to increase your cardiovascular strength as well as muscular endurance. Running and skipping rope are my choice of an endurance workout.TRX - SUSPENSION TRAINING
is a complete body workout which strengthens your core, builds muscle and burns calories! It is functional training which will prepare your body for what you do and want to achieve. Applying body weight exercises with the suspension trainer, you will gain core stability, flexibility, strength and endurance."Train hard, eat right and live inspired" -Tod Dunkin


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3D Printing or Plastic Injection : our guide to cost efficiency
Posted By Alexia Toulmet on Nov 19, 2014 | 0 comments
It's out! We're happy to announce the launching of our Guide to Cost Efficiency through Short Series Manufacturing.
There's no need to prove how useful 3D Printing is for Rapid Prototyping. Or even to create customized objects. However, the advantages that the technology presents can go far beyond that.
Advancements in pricing and online technologies (specifically Sculpteo's Batch Control tool) have opened the world of 3D printing into that of manufacturing – into direct and exciting competition with injection molding, the current standard in manufacturing.
In order to perfectly understand the main advantages of 3D Printing for short series production, we made a comparative analysis of the respective advantages and drawbacks of each technology when it comes to production. We have led our studies, depending on the following criteria:
- The number of units produced
- The volume of the object
- The complexity of the object's design.
The study confirms that 3D printing is an economically viable solution for manufacturing particularly for objects with complex design features. It presents designers and product developers a new mode of accomplishing and designing their product's objectives.
Currently, 3D printing does not offer a replacement for injection molding, however it does provide an additional, financially responsible option for manufacturing. The study is meant to offer business of any size the knowledge to successfully design and produce their objects.
To get a better understanding, you can easily download the guide on our website.


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'Scoob!' Tops Redbox Disc Rentals for Second Week
August 5, 2020
Warner Bros. Home Entertainment's Scoob! remained in the top spot on the Redbox kiosk disc rental chart the week ended Aug. 2. The animated film was released on disc July 21 after a premium VOD run.
Universal Pictures Home Entertainment's You Should Have Left was the No. 2 disc rental and debuted at No. 1 on the Redbox On Demand chart, which tracks digital rental transactions.
Warner's direct-to-video Deep Blue Sea 3 was the No. 3 title on Redbox's kiosk disc rental chart, which tracks DVD and Blu-ray Disc rentals at the company's more than 40,000 red kiosks. Redbox offers early availability of the disc, which will be widely released Aug. 25.
Lionsgate's Survive the Night was the No. 4 title on the disc rental chart and No. 10 on the digital chart.
Universal Pictures Home Entertainment's Trolls World Tour, the top On Demand title the previous three weeks, slipped to No. 2 on that chart. It was No. 5 on the disc chart.
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Rounding out the top five on the On Demand chart were Sony Pictures' Bloodshot at No. 3, Universal Pictures' The Invisible Man at No. 4 and Screen Media's The Outpost at No. 5.
Top DVD and Blu-ray Disc Rentals, Redbox Kiosks, Week Ended Aug. 2:
- Scoob! — Warner
- You Should Have Left — Universal
- Deep Blue Sea 3 — Warner
- Survive the Night — Lionsgate
- Trolls World Tour — Universal
- Grand Isle — Screen Media
- The Invisible Man (2020) — Universal
- Force of Nature — Lionsgate
- Bad Boys for Life — Sony Pictures
- Becky — Redbox
Top Digital, Redbox On Demand, Week Ended Aug. 2:
- You Should Have Left — Universal
- Trolls World Tour — Universal
- Bloodshot — Sony Pictures
- The Invisible Man (2020) — Universal
- The Outpost — Screen Media
- Bad Boys for Life — Sony Pictures
- Force of Nature — Lionsgate
- Sonic the Hedgehog — Paramount
- The Secret: Dare to Dream — Lionsgate
- Survive the Night — Lionsgate


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Pierre Wesselrin is a 40-year-old American who lives in Paris by sponging off his working friends and various wealthy acquaintances. He receives a telegram saying that a rich aunt has died, so he throws a party, using borrowed money of course, and invites all his friends. After discovering that his aunt disinherited him, his luggage is impounded and he is thrown out of his apartment. All his friends are now away for the summer, or are working outside Paris, so he is forced to wander the streets and become a clochard.
Also Known As (AKA): O Signo do Leão, Il segno del leone, El signe del lleó, Im Zeichen des Löwen
File Name : Le signe du lion 1959.mkv
File Size : 3969.33 MB
Resolution : 1184×720
Duration : 01:43:00
Video : AVC, 24.000 FPS
Audio : DTS (VBR), 48.0 kHz, 1 channel, 1 stream
Quality: BRRip
Language: French
Subs: English, Spanish (embedded)
Country: France
Genres: Drama


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Former Egyptian President Mohamed Morsi stands inside a glass defendant's cage during the hearing in police academy in Cairo, Egypt on May 16, 2015. [Photo/IC] |
Only two hours after the Cairo Criminal Court sentenced Morsi and dozens of Muslim Brotherhood (MB) leaders and affiliates to death over jailbreak and espionage charges, a group of militants opened fire at a car carrying judges in Al-Arish City, killing three of them together with their driver.
Three other judges were critically injured in the attack.
Police rushed to the scene, cordoned off the area and started an investigation to identify the assailants.
No groups have claimed responsibility for the attack. However, analysts say it is more likely that the assault was carried out by the Sinai-based Ansar Bayt al-Maqdis, which has recently pledged allegiance to the Islamic State (IS) regional militant group.
Saturday's attack raised fear that judges will be the new targets for militants who have been targeting army and policemen across the country.
This urged Egyptian President Abdel-Fattah al-Sisi to order security forces to provide protection for workers of the judicial system, according the State TV.
Military operations escalated notably in restive Sinai Peninsula after the ouster of Morsi by the army in response to mass protest against his one-year rule in 2013.
Anti-government attacks have extended lately to reach the capital Cairo and other provinces across the country.
Meanwhile, Saturday's Cairo Criminal Court ruling was the first death sentence against an Egyptian leader in modern history.
The former president and 105 other defendants, most of whom are members of the Palestinian Hamas group, were sentenced to death over 2011 jailbreak in the case publicly known as the "Wadi al-Natron jailbreak."


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It's being reported that Disney and Sony Pictures are working on a new deal with the Spider-Man film property that should get Spider-Man very happy.
This news comes from a pretty well-know 'scoopster' on Twitter called Roger Wardell.
His track record has been a bit spotty over the years, but he does often get good intel.
He's now taken to Twitter to reveal that Disney and Sony Pictures might be working on a new Spider-Man deal together.
You might remember that Sony and Disney almost failed to renegotiate the Spider-Man movie franchise contract last year.
That would have meant Tom Holland's Spider-Man might not have been able to star in the MCU movies.
Thankfully, they worked things out, and they might be looking to make even more Spider-Man movies together.
Sounds like Disney and Sony might be renegotiating that Spider-Man contract
Read more: The Umbrella Academy Season 3 Is Already In The Works At Netflix
Here's what Roger Wardell wrote on Twitter about this new Spider-Man deal:
Disney understands the money-making powers of Spider-Man while Sony is aware of being completely unable to compete with the Mouse at the moment. New agreement should please many Marvel fans.
He doesn't do into any specifics, yet here's hoping that Disney and Sony do work things out.
I'd love, for instance, to see Miles Morales be brought into the MCU at some point.
What do you make of this news?
Would you like to see more Marvel and Sony Spider-Man movies moving forward?
Let us know your thoughts in the comments below.
What do you make of this story? Let us know in the comments below or on our Facebook or Instagram pages!
And if you enjoy listening to film podcasts, why not check out our podcasts, Small Screen Stories and Small Screen Film Club wherever you get your podcasts!


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Immersive exhibition presents virtual reality work about the millennial human migrations and transculturalism.
Picture: Gabriel Mario Velez
A VR artwork is calling the attention of curators and of the audience – The Transeuntis Mundi. Created by a duo of Latin American artists and Scholars, it's an immersive experience about the migration phenomena that permeates human's history.
The Transeuntis Mundi, in Latin, proposes to capture the sound and visual memory of peoples, cultures and places to generate an archive of human cultural heritage. It is about the story of the millennial passersby that have been crossing the world and it aims to evoke the power of ancestry, identity and legacy.
This project was created in 2018 by the Brazilian artist Cândida Borges and the Colombian artist Gabriel Mario Vélez – two artists and immigrants based in NYC, academic researchers about the field of composition in emerging technologies. They consider their migrational experience and cultural backgrounds as the reference for creating this poetical/technological work.
In this current version, named "Web Derive 01", New York, Austin, Rochester and McAllen are some of the cities presented in the work – exactly for its force representing the blend of cultures, genetics, and borders. Other countries are the UK, Brazil and Colombia, completing 4 continents of exploration of this piece.
The work was launched in 2019 and since then over 3000 people have experienced the in-person installations throughout Medellín, New York, Miami, Rio de Janeiro, and Rochester. Online since the beginning of the pandemic, the project has accumulated invitations to perform in international festivals and conferences, while they wait to resume in-person exhibitions.
Radically immersive way to experience art and culture
Virtual reality is the top medium when talking about immersive art nowadays. By virtually migrating inside the VR headset, the visitors are invited to experience the power of traveling through cultures and places. Online and powered by computers and phones, it offers the visitor the chance to experience its landscapes in 360-degree audio and video. Voices and languages, cars, music, trains, bells, wind, claps, phone rings, everything moving and becoming a spatialized experience over the internet, that finally unveil little spontaneous narratives of everyday life events.
The current exhibition is at the platform Artsy, one of the most prestigious media for Art collectionists. It's hosted by The Light Gallery and promoted by the great Colombian/British curator Luz Osorio. This is a unique opportunity to enjoy and acquire a piece of the small and very exclusive collection of the Transeuntis Mundi Project. The current series presents the VR work "Derive 01", a series of 9 photographies and a luxury photography book signed by the artists.
The Transeuntis Mundi will be online touring through many international festivals during this pandemic year. Next exhibitions will be hosted at the Manizales Festival (Colombia), NIME Festival 2021 from Shanghai (China) and at the Museum of Contemporary Art in Rio de Janeiro (Brazil). Check and follow www.transeuntismundi.com for more information.
Till May 21st – Artsy Exhibition
Junho, 15 a 18th – NIME 2021 – Shanghai, China. Online.
Trailer: https://www.youtube.com/watch?v=kY3rjcffP_c&feature=emb_title .
To know more about the work Transeuntis Mundi:
PICTURES: https://transeuntismundi.com/gallery/


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Top 10 Tips to Homeschool Middle School History
This post may contain affiliate links. For more information, please read my disclosure policy.
Are you planning to homeschool middle school history?
Don't worry! Middle school history is easy and fun to teach using these ten tips.
Tips to Homeschool Middle School History
1. Use Historical Fiction
Historical fiction is a fabulous way to bring different time periods to life when you homeschool middle school history.
Kids experience life as the character sees it. The problems become intimate. And children remember history.
I don't use only historical fiction when I homeschool middle school history. But it's a great addition to spice up your regular history studies!
2. Chronological
Keep history chronological and start at the beginning. It's hard to understand the Dark Ages without understanding the Romans.
It's hard to comprehend the importance of the Renaissance if you don't know about the Dark Ages.
To be honest, kids in middle school love to read about Egyptian mummies and pyramids, the Roman gladiators, and Vikings.
There are a lot of fascinating facts to learn about history.
3. Choose a Core
Choose a core text to guide your way through history. This is a book or textbook that covers all of history.
The book doesn't need to be thick or detailed. It's simply an overview of what is going on.
You and your child read about a time period, person, or event before writing a short narration about what you learned.
Then you encourage rabbit trails.
And here's a list of recommended history books you can use as a core.
4. Encourage Rabbit Trails
Rabbit trails are the detours you take in your studies. Because the core text is simply giving you an overview of the time, place, and people, you need to research to fill in the holes.
This is the time to encourage your child to investigate something interesting about the time.
Since most middle school kids will be studying history again in high school, you don't need to try to learn everything.
Focus on the most fascinating bits with your child. You never know where these rabbit trails will lead.
5. Horrible Histories are Fun
If you've never read a Horrible History book, you've missed a terribly delightful treat.
The Horrible History books concentrate on the fascinating bits of history that make you cringe, gross you out, and make you grateful to live in 2016.
Middle school kids adore these books, and they do teach a lot of history in between the EWWW factor.
6. Use Elementary Level Books Liberally
There's no reason to insist your middle school child uses only difficult reading material.
Reading material that is meant for younger children is easy to read, easier to understand, and helps to teach kids research skills.
Use literature and difficult history books when you homeschool middle school history. But encourage your child to use elementary books for research papers.
And focus on the skills you're teaching.
7. Write Papers
History has fodder for many, many writing assignments. Have your child write research papers about their favorite historical topic.
They can write compare and contrast papers writing about the difference between Roman gladiators and the Greek Spartans.
You can even write short stories about characters living during the historical time period you're studying.
8. History Projects
Don't forget the many, many historical projects you can do. Create the armor of a crusader. Build salt maps of the United States or Europe.
Try your hand at weaving or creating urns.
Check out books such as Victorian Days for ideas on projects, activities, and recipes to try as you study history.
9. Study with Friends
Make a study group of friends. You can meet once a week or once a month at various houses.
Assign topics to be studied individually.
Come together to exchange research and do projects together.
You can try reenactments together or have medieval or Roman dinners.
There's even the possibility of getting all the families together every few months for a big historical bash.
10. Homeschool Middle School History And Have Fun
Middle school does up the amount of information that needs to be learned, but have fun along the way.
Encourage projects and research. Watch movies and documentaries.
Don't worry about learning every historical detail.
Instead, concentrate on enjoying your studies and deepening your child's love of learning.
It's fun to homeschool middle school history! The stakes aren't as high as in high school, but the kids are ready for more learning and discussion.
Relax, take your time, and do a few projects along the way.


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Bred by Swamp Boys (Instagram @swampboysseeds)Wedding Cake x GMO/ TK Skunk
Not for beginners. This strain has immediate cerebral effects followed by a rush of energy throughout the body. The cerebral effects are very potent and long lasting with surprisingly little to no crash, which can be reminiscent of a strong Sativa.


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BMW has revealed the shape of things to came for its M-series with the sexy Concept M4 Coupe. Unveiled at the annual Pebble Beach/Monterey automobile weekend, the Concept M4 picks up where the M3 left off with a design that holds to the "race car for the road" philosophy of the company's Motorsport line.
BMW Concept M4 Coupe
The carbon fiber roof helps ensure a lower center of gravity and reduces weightBMW
The M4 features twin tailpipes, a characteristic synonymous with the M-series
The M4 combines motor racing genes and unrestricted everyday suitability in a highly emotional overall concept," says Dr. Friedrich Nitschke, President BMW M Division.
Flashing an exclusive "Aurum Dust" color scheme, the design preview of the upcoming M4 leaves no doubt as to the car's heritage. The front end is is marked by large air inlets and the traditional BMW face, with its twin round LED headlamps and the iconic power dome hood a clear nod to previous M models, as are the twin tailpipes at the rear.
Buffed out wheel arches shelter the 20" alloy rims fashioned in the traditional M style – five filigree double-spokes with polished outer surfaces that provide a window to the M Carbon ceramic brakes.
The M4 also sports a carbon fiber reinforced plastic (CFRP) front splitter, roof, and rear diffuser. The CFRP roof helps reduce weight and lower the vehicle's center of gravity while the rear diffuser increases down force and adds to the brawny look of the coupe's back end.
While no official performance specs or drivetrain details have yet been released, BMW says this new concept offers a "first outlook on a high-performance sports car of tomorrow." It has certainly proved its ability to turn a few heads at Monterey.
A production version of the M4 is expected in 2014.
You have read this article with the title BMW unveils Concept M4 Coupe. You can bookmark this page URL https://astrofuturetrends.blogspot.com/2013/08/bmw-unveils-concept-m4-coupe.html. Thanks!
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RC - Monday, August 26, 2013


text: You are here: Home>Archive>WHERE THE LINES MEET>Oral history audio recording of Dorothy Hendry (b.1934). Oral history audio recording of Dorothy Hendry (b.1934). The new Bletchley electric signal box, 1965. An interview covering memories of the wife of a signalman in Bletchley from the 1950s onwards. Topics include memories of Bletchley, living at Railway Terrace, family holidays by train, the Great Train Robbery and the Beeching cuts. Creator Hendry, Dorothy Extent 1 audio tape cassette Reference number WLM/033 Records in this Group Interview about memories of life as a railway family in Bletchley from the 1950s, and related events. WLM/033/001 Dorothy Hendry remembers her first visit to Bletchley Station and to the town: a 'quaint little town'. On moving to Bletchley they first lived in Railway Terrace, which she describes as 'a nice community', everyone was connected with the railways. Talking of family life there, she mentions the Newfoundout, the old railways sheds and the ... No Comments Start the ball rolling by posting a comment on this page! Add a comment about this page Your email address will not be published. Required fields are marked *Your comment:Name * Email * Website Save my name, email, and website in this browser for the next time I comment. I consent to my name and e-mail address being stored along with this comment, and to the website editors communicating with me by e-mail about the comment if necessary. My name may be published alongside the comment on the website, but my e-mail address will not be published. My information will not be shared with any third party (see our Privacy Statement - opens in a new window). * Δ In this collection Our archive Collection: WHERE THE LINES MEET Group: Oral history audio recording of Dorothy Hendry (b.1934). Item: Interview about memories of life as a railway family in Bletchley from the 1950s, and related events. Search the archive Text search Date search


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Much has been said about Princess Diana's iconic style, but though her dresses were deserving of every headline, so was her jewellery, and I'm not just referring to that engagement ring which she redesigned after Prince Charles gave it to her.
The royal had an extensive collection (which Kate Middleton and Meghan Markle inherited), which included an initial necklace long before they were trendy, as well as two special watches and of course, many, many diamonds.
Di was said to also love sapphires, and in fact quite a few of her favourite pieces included the gemstone. One of her favourite necklaces, which she wore all the time, was a three strand pearl choker, with at its centre a giant sapphire surrounded by diamonds.
She was photographed wearing it at many events in the late 80s and 90s, including a ball in Vienna, a concert at the Royal Albert Hall, the Met Gala and, most famously, at the Serpentine Gallery event where she debuted the revenge dress.
The story behind it is rather unusual, since the piece didn't start off as a necklace at all, but as a brooch. It was a wedding gift from her grandmother-in-law, the Queen Mother.
Diana wore it pinned to her Belville Sassoon gown at a Downing Street banquet in 1982, and although she wore it as a brooch a few times, she quickly had it mounted onto a seven strand pearl choker.
Since the royal didn't wear brooches much, she therefore created a piece she knew she would get much more wear out of. Whilst we don't know the exact date she had the piece made, we do know she was first photographed wearing it at President Ronald Reagan's ball in Washington in 1985.
A famous pictures shows her being twirled around the dancefloor by John Travolta, in a velvet off-the-shoulder gown, set off beautifully by her precious necklace.


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On this week's episode of Fast Facts – Perio Edition, Katrina Sanders, RDH wrap up the breakdown of the AAP 2017 Classification System highlighting state 4.
"These are patients in which there is complex management required in order to stabilize the patient's existence of this disease."
"It is imperative to understand that this adequate rehabilitation is being done in order to preserve the remaining dentition."
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More Fast Facts: https://www.ataleoftwohygienists.com/fast-facts/
Katrina Sanders Website: https://www.katrinasanders.com
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Papapanou, P. N., Sanz, M., Buduneli, N., Dietrich, T., Feres, M., Fine, D. H., … & Tonetti, M. S. (2018). Periodontitis: Consensus report of workgroup 2 of the 2017 World Workshop on the Classification of Periodontal and Peri‐Implant Diseases and Conditions. Journal of periodontology, 89, S173-S182.


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Eitel Wolf Dobert
Eitel Wolf Dobert was born in Germany in 1895. As a young man he struggled to make a living as a writer and lecturer. In the 1920s he joined the National Socialist German Workers Party (NSDAP). After visiting France he published A Nazi Discovers France (1932). The book sold well but it upset the Nazis and when they gained power he fled to Switzerland.
In 1933 Dobert married Margarita Siniossoglou in Geneva. According to Gary Kern she was "a slim, bob-haired Greek born in Istanbul, but raised in Berlin and able to speak German, French, and Italian." With her and his camping equipment on the back of a motorcycle, he embarked on a tour of Europe. David Dallin has argued that during this period he began working for Walter Krivitsky: "Eitel Wolf Dobert was a young Nazi when Walter met him in Germany, but with pacifist leanings. He broke with Nazism, went to Paris and became Walter's secret agent, making many trips to Germany."
In early 1939 Eitel and Margarita Dobert moved to the United States and settled in Cold Spring. Soon afterwards he went to see Paul Wohl and Krivitsky who were living at 600 West 140th Street. Krivitsky had recently fled to the United States and suspected Dobert was a NKVD agent who had been sent to kill him. However, eventually Krivitsky began to trust the couple and they spent a great deal of time together. During this period Dobert became friends with Max Eastman, the well-known writer and biographer of Leon Trotsky.
In the summer of 1940 Eitel and Margarita Dobert purchased a 90-acre farm in Barboursville, about 15 miles north of Charlottesville, in Virginia, for $1,000. The Doberts moved into a two-room log cabin and decided to raise chickens. Margarita later recalled: "My God, it was hard! We nearly starved. When we made $50 a month it was a great month."
On Thursday 6th February, 1941, Walter Krivitsky visited the Doberts. Soon after arriving Krivitsky purchased a .38 caliber Colt automatic pistol and cartridges at the Charlottesville Hardware store. On his return to the farm he and Dobert began target practice. By 8th February he had run out of ammunition. Margarita Dobert later commented: "On Saturday he asked me to drive to town and buy 150 cartridges for the gun."
On Sunday 9th February, Krivitsky checked into the Bellevue Hotel in Washington at 5:49 p.m. He paid $2.50 in advance for the room and signed his name in the register as Walter Poref. The desk clerk, Joseph Donnelly, described him afterwards as nervous and trembling. At 6:30, he called down for a bottle of Vichy sparkling water. The bellboy considered him a typical foreigner - "quiet and solemn".
The young maid, Thelma Jackson, knocked on Krivitsky's room at 9.30. When she did not receive an answer she assumed the room was free for cleaning and inserted her passkey. She opened the door and discovered a man lying on the bed the wrong way round, with his head toward the foot. She noticed he had "blood all over his head". The police were called and Sergeant Dewey Guest diagnosed the case as an obvious suicide. Coroner MacDonald issued a certificate of suicide that afternoon.
Krivitsky left behind three suicide notes, each one in a different language known to him (English, German and Russian). Police handwriting expert, Ira Gullickson, was shown the notes found with the body and declared that they were without any question written by the man who signed the hotel register. Gullickson argued that the notes were written on different times, because they showed an increase in nervous tension.
The first letter, in English, was addressed to Louis Waldman: "Dear Mr. Waldman: My wife and my boy will need your help. Please do for them what you can. I went to Virginia because that there I can get a gun. If my friends should have trouble please Mr. Waldman help them, they are good people and they didn't know why I bought the gun. Many thanks."
The second suicide note, in German, was addressed to Suzanne La Follette: "Dear Suzanne: I believe you that you are good, and I am dying with the hope that you will help Tonia and my poor boy. You were a good friend." This letter raised several issues. It is true that in the early days of their relationship he did write in German because his English was poor. However, in recent letters, he had used English.
The third letter was to his wife, Antonina Porfirieva: "Dear Tonia and dear Alek. Very difficult and very much want to live but I can't live any longer. I love you my only ones. It's difficult for me to write but think about me and you will understand that I have to go. Don't tell Alek yet where his father has gone. I believe that in time you will explain since it will be good for him. Forgive difficult to write. Take care of him and be a good mother - as always be strong and never get angry at him. He is after all such a such a good and such a poor boy. Good people will help you but not enemies of the Soviet people. Great are my sins I think. I see you Tonia and Alek and embrace you."
Gary Kern, the author of A Death in Washington: Walter G. Krivitsky and the Stalin Terror (2004) claims that two sentences in this letter cause certain problems: "Good people will help you but not enemies of the Soviet people. Great are my sins I think." He goes on to argue: "These two statements have the look of a political recantation and, as such, suggest either a mental breakdown or something dictated by the NKVD."
On hearing of Krivitsky's death, his lawyer, Louis Waldman, called a press conference and announced that he had been murdered by the NKVD and named the killer as Hans Brusse. (1) An NKVD agent (Hans Brusse) who had twice before tried to trap Krivitsky had appeared in New York City, where Krivitsky lived. (2) Krivitsky planned to buy a farm in Virginia, thus he intended to live. He had changed his name, applied for citizenship, bought a car. (3) The NKVD was expert in forgery and had samples of Krivitsky's hand in every language.
At the White House, Adolf Berle, President Roosevelt's advisor on national security wrote in his diary: "General Krivitsky was murdered in Washington today. This is an OGPU job. It means that the murder squad which operated so handily in Paris and in Berlin is now operating in New York and Washington." Joseph Brown Matthews, who was an investigator for the House Committee on Un-American Activities, commented: "It's murder. I have no doubt of it." New York Times reported that Krivitsky had told them: "If they ever try to prove that I took my own life, don't believe them."
One of the most surprising aspects of the case was that rooms on both sides of Krivitsky had been occupied. So had the rooms across the hall. In the past, guests had often complained about noises in the room next to them because of the thinness of the walls. However, no one heard gunfire in the quiet early morning hours when the suicide had taken place. The gun found in Krivitsky's room did not have a silencer.
The Washington Post argued: "All in all, it would seem that the Washington police and coroner disposed of the case in rather summary fashion... The whole thing looks like a pretty careless piece of work." Frank Waldrop of The Washington Times-Herald ridiculed the police investigation: "Anybody'd rather be a second-guessing citizen than Chief of Police Ernest W. Brown, with such a staff of lunkheads to do the field work in homicide matters." However The Daily Worker disagreed: "The capitalist press is desperately trying to make a frame-up murder case out of what is clearly established in the suicide of General Walter Krivitsky."
Alexander Kerensky believed Hans Brusse had murdered Krivitsky: "Hans Brusse is the man. The most vicious murderer in all the Soviet. We know him. We know his methods. His favourite tactic is to drive a man to suicide by threatening to capture and torture his family. It has been done many times in many countries. I believe Krivitsky got a concrete warning recently that they would kill him or kidnap his family. That is their favourite plan of operation. Krivitsky had a burning mission to expose Stalin for what he is. And in my opinion he was not the type to commit suicide."
Whittaker Chambers definitely believed that he had been killed by the NKVD: "He had left a letter in which he gave his wife and children the unlikely advice that the Soviet Government and people were their best friends. Previously he had warned them that, if he were found dead, never under any circumstances to believe that he had committed suicide." Krivitsky once told Chambers: "Any fool can commit a murder, but it takes an artist to commit a good natural death." Martin Dies, Isaac Don Levine and Suzanne La Follette all believed Krivitsky was murdered.
However, Eitel Wolf Dobert, told reporters that Krivitsky seemed very worried and probably had committed suicide. He also thought that Krivitsky had written his suicide notes the last night that he stayed on his farm. Mark Zborowski, who was later exposed as a NKVD agent who had been involved in the death of Lev Sedov, also believed Krivitsky committed suicide. He told David Dallin: "He was a neurasthenic and a paranoiac, eternally in fear of assassination. He felt that he was a traitor. As a Communist, he did not have the right to do what he was doig. He had days of high spirits and days of dejection."
Paul Wohl also disagreed he had been murdered. He said: "When we lived together, he often talked of suicide." Wohl also dismissed the idea that Hans Brusse killed Krivitsky. He claimed that although he was a Soviet agent he was not the type "to be assigned to assassinations, but rather a technician". Gary Kern, the author of A Death in Washington: Walter G. Krivitsky and the Stalin Terror (2004) has pointed out: "If Hans were so innocuous, one has to wonder, then why had Wohl sent his letter of warning to Krivitsky in the first place... And if he were not an assassin, but a technician, then what was he doing in America on a political assignment? And how did Wohl, a private citizen, know about any of these things?"


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Some of the more exciting ideas in biotech are coming up in molecular diagnostics. There's cool science at work. A number of tests have potential to cut down on overtreatment, reduce waste in healthcare, and give physicians clever new ideas on how to help patients.
But this industry, which accounts for less than 2 percent of healthcare spending, is stuck in neutral. If it's ever going to grow into a bigger business that delivers lots of valuable information about health, the molecular diagnostics industry needs a tough, science-minded, credible regulator. It needs a thorough, predictable, and efficient third party who can comb through complex data sets and say with confidence what's real, what's clinically meaningful, and what's BS.
Physicians, patients, and payers aren't just going to do this by themselves.
Just like the pharmaceutical industry, the diagnostics world needs a strong FDA.
"We have to have some kind of pathway that gets rid of the uncertainty hanging over the whole space now," says Kim Popovits, CEO of Redwood City, CA-based Genomic Health (NASDAQ: GHDX), a leader in molecular diagnostics.
While the FDA has done some things in recent years to improve how it reviews companion diagnostics that help guide treatments for cancer, there is still a vast swath of the diagnostics world that is lightly regulated at best. It allows for skepticism about these tests to fester among payers, and spawns fear among investors who worry the payers will never pay. "We'd like a process that has clarity and some certainty around how you do it," Popovits says. "When you develop a drug, you go through Phase I, II, and III, and then you go to FDA. They say 'yea or nay,' and then you get reimbursed. That's a process we need."
For sure, the idea of tough, consistent FDA regulation of diagnostics isn't new. The FDA has been making noises for years about getting more aggressive about regulating "high-risk" laboratory-developed tests (LDTs) that influence big healthcare decisions like how to treat a cancer patient—where the consequences of a false test can be dire. AdvaMed, the trade group for medical device and diagnostic companies, has said the FDA should regulate "higher-risk" tests. Industry leaders Brook Byers of Kleiner Perkins Caufield & Byers and Mara Aspinall of Roche's Ventana Medical Systems unit co-wrote an op-ed for the Boston Globe in 2011 about why they think the FDA should bring more rigorous regulation to the diagnostics business.
"For one thing, both payers and physicians need and deserve to have confidence that the advanced diagnostic methods being used are reliable and accurate," Byers and Aspinall wrote. "As it stands today, diagnostics are regulated by a variety of state and federal agencies, but there are, as yet, no clear policies in place for the approval of new molecular diagnostics."
Not a whole lot has changed on the regulatory front in the last couple years, but a lot has changed in the technology world. Consider some recent diagnostics stories:
—Cambridge, MA-based Foundation Medicine (NASDAQ: FMI) introduced a test in 2012 that takes a tumor sample from a cancer patient and scans it for alterations in 235 cancer-related genes to see what might be driving the tumor. Like many other lab-based companies, Foundation Medicine's lab is certified under the usual Clinical Laboratory Improvement Amendments (CLIA) standard—a pretty low bar. The company has published its analytical methods in a top peer-reviewed journal, going further than most of its peers. But the Foundation Medicine test is not approved by the FDA for providing a clinically validated, health-outcome altering diagnostic test. Medicare still hasn't come out with a consistent policy saying what the test is worth. The result? Foundation Medicine has to fight tooth and nail, and negotiate with payers, to get reimbursed each time a patient gets its test.
The company, to its credit, acknowledges the barrier to entry is pretty low, and it's willing to jump over higher regulatory hurdles. "The stakes are high. You have really ill patients. There are doctors without a lot of bandwidth to reconcile conflicting results. We have to be right in what we report out to oncologists and pathologists," says Vince Miller, chief medical officer of Foundation Medicine. "As we continue in this era of precision medicine, the good news is that the value of molecular diagnostics in cancer should go up. We're certainly prepared and hopeful that the barriers to entry and new standards will be raised as well."
—South San Francisco-based Crescendo Bioscience just enjoyed a big success, being acquired by Myriad Genetics (NASDAQ: MYGN) for $270 million. Crescendo, another lightly regulated CLIA lab, developed a proprietary test that looks at 12 proteins in a blood sample of patients with rheumatoid arthritis. It's the first-ever quantifiable way of measuring the molecular activity of this common inflammatory disease. It's a radical new idea in a world where physicians—even in 2014!—basically just squeeze knuckle joints, ask patients how much it hurts, and then make a subjective judgment on what to do next. The Crescendo test has the potential to tell a physician when a cheap generic drug is holding the disease in check at the molecular level, or when a $20,000 a year biotech drug isn't getting the job done. Without going through an FDA clearance process, Crescendo had a pretty easy path to the market. But it took Crescendo three years on the market before it could get Medicare reimbursement at $575 per test. After a decade of work and $100 million in venture capital, the company got to the point
of $10 million a quarter in revenue—enough to entice Myriad to buy. Even after Medicare has signed off, Crescendo still has its work cut out explaining the value of its test to payers.
—Genomic Health has sought to commercialize a new test for prostate cancer over the past year, and presented some solid clinical data about it last year at the American Urological Association annual meeting. But the service hasn't truly caught on, partly because the company and the investigators who conducted the key prostate cancer study haven't yet gotten the results published in a top peer-reviewed journal. Without results published in a peer-reviewed journal, the company can't really talk turkey with payers. The peer-review process can take months, or maybe more than a year, and even then, peer-reviewers can't provide the same level of scrutiny that full-time professional FDA staff can provide.
—Madison, WI-based Exact Sciences(NASDAQ:EXAS), has had an impressive run in the stock market over the past year, in no small part because of its unusual embrace-the-FDA-fully strategy. The company has developed a molecular test that screens for early signs of colorectal cancer in a stool sample—a less invasive approach than traditional colonoscopy. Although Exact could have taken a cheaper, easier route to the market by simply running a small clinical trial to show the test's value, and then set up a CLIA lab, it chose to go the extra mile to satisfy the data hounds at the FDA. Exact Sciences is now preparing for a FDA advisory panel meeting on March 27, in which expert advisors to the FDA will debate the merits of Exact's colon cancer screening test in public. Exact is actually in parallel talks with the FDA and Medicare, to both evaluate the quality of its data, and determine what it's worth, in one fell swoop. "We felt (FDA approval) would be helpful in commercialization of the test, because more doctors would have confidence in it, and insurers would have confidence, as would the Medicare system," CEO Kevin Conroy told me in November.
Naturally, there is a downside to submitting to regulation. It raises the barriers to entry for new market entrants, increasing the time and expense to develop new tests. Some tests probably won't get developed that might be useful for patients. It would stifle some innovation. If the regulators are incompetent, excessively risk-averse, too slow, or deaf to the needs of patients, it could be a disaster. Somebody, i.e. the taxpayers and the companies themselves, is going to have to foot the bill for extra staff and resources to help the FDA carry out this expanded mission.
These all seem like reasonable trade-offs to me. In the pharmaceutical industry, we're willing to accept a little less innovation so that we can be confident of a safe, effective, well-regulated U.S. drug supply. The FDA is far from perfect, but it's pretty good at what it does. When the FDA messes up a drug review, it's front-page news, which means that it's still unusual and unexpected. It would be unthinkable for any politician to put the FDA out of the drug regulation business.
I happen to believe that some types of markets, especially those that are highly technical and high-stakes like the world of diagnostics, tend to function better with tough, trusted regulatory bodies. An unregulated Wild West free market is great if you're selling books online or consumer smartphone apps. It's not such a great thing when you're talking about credit-default swaps or cancer drugs.
Professional medical societies already do set some standards, and sign off when they think a diagnostic test is well validated enough for standard practice. Peer-reviewed journals have a role here too, in separating good data from bad. Payers are increasingly building up some of their own expertise to make science-based judgments.
All of that effort can and should continue, but I would argue those things together aren't enough to inspire confidence in molecular diagnostics. "There is a hodgepodge system vouching for quality of diagnostic tests," says Brad Gray, CEO of Seattle-based NanoString Technologies, the developer of a molecular diagnostic test for breast cancer. "There's no good housekeeping seal of approval on these products. We have to make a decision, as an industry, not just diagnostics, but the whole healthcare system, about what to do."
These molecular diagnostics represent the long-awaited payoff from society's investment the past couple decades in basic biology and genomics. And it's precisely because of the long investment in basic science that we should make a corresponding investment in science-based regulation. I'm not saying every single test in the tens of thousands of labs around the U.S. needs to go through an FDA approval test—it's just not practical and necessary for everything, especially for simple one-off blood tests in hospitals. But if we stick with the system we have now, society will get very few widely-used molecular diagnostic tests. A bit of well-crafted regulation, led by smart people at the FDA with the resources to do their jobs, could go a long way toward delivering on the promise of precision medicine.


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The Department of Labor (DOL) recently released its first set of rolling FAQ guidance regarding its new rules expanding the definition of fiduciary investment advice under the Employee Retirement Income Security Act of 1974 (ERISA) and the Internal Revenue Code of 1986 (Code), adopting new prohibited transaction exemptions (PTEs), and amending certain previously existing PTEs. The DOL answered questions regarding the new PTEs and the amendments to existing PTEs under ERISA and the Code. The DOL also reaffirmed the applicability date of April 10, 2017, stating that this date provided adequate time for financial service providers to adjust to the rule changes.
One common area of confusion regarding the new rules was the extent to which the new Best Interest Contract (BIC) exemption would be available for use by discretionary investment managers. One of the conditions to use of the BIC exemption is that the fiduciary not have any discretionary authority or control with respect to the recommended transaction. This excludes a large portion of investment advisers that serve as discretionary investment managers. However, there are limited circumstances in which they can receive protection under the BIC exemption.


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Abhi telling Pragya that he got Kiara and his DNA test and it matched. He says it is clearly written that Kiara is my daughter, our daughter. He says why did you hide this from me, what was your helplessness. He asks how can you hide such a big truth from me and asks her to tell. Pragya cries and gets emotional. She hugs him and says I was scared. Abhi asks why? Pragya says I thought if I take Kiara to you, then you will take her and will punish me for the mistake which I haven't done. Abhi says didn't you see love in my eyes. He says Kiara was away from her father for many years and asks what do you think that I will separate her from her mother.
Pragya says sorry. Abhi says you gave me such a big happiness, that I can leave my life, but not you. He says I don't want kiara alone, but my family. He says both of you are similar and says when I see her, I miss you and when I see you, I miss her.
He says did I say you that I came in this world to meet you and love you. He says today if I am alive is because of you, so I want to stay with you, live with you. I can't separate Kiara from you. He says first we were two, now we are three. He says I am pleading and begging infront of you and asks can I get my Kiara and family. He says I can't stay without you both and promises her that he will not fight with her and will not let her go. He says I can do anything if you are together. Pragya says we will stay together, you, me and Kiara. They have a hug…It turns out to be Abhi's dream. He thinks I have started dreaming again and says I am going alone, but will return Kiara and Pragya.
King is at home and thinks of Pragya's words. He thinks why Pragya met me and asked help from me, she made my career and says he didn't understand the Karmic connection. He thinks he listens to Pragya and realizes he is in love with her. He thinks Chachi had told me, and thinks if she is right about me then she is right about Abhi. He thinks if Abhi has feelings for Pragya. Abhi comes to King's house.
Bahadur is standing at the door and tells Tanu that nobody came. Tanu says I know. Disha hears them. Bahadur asks her to go to her room and says he will bring the report to her room. Tanu scolds him. Disha hears them. Door bell rings. Tanu sends Bahadur to kitchen and opens the door and gets the report. She checks the report and reads that sample was contaminated. She thinks Abhi couldn't prove that Kiara is his daughter, then why he was happy. He shall be sad and thinks he might be happy to make her feel sad or jealous, and thinks it is good. She thinks once Abhi loves her then she shall not be scared from Pragya. Disha is hiding and smiling. She recalls waiting outside and colliding with the delivery guy and replacing the reports. She thinks Tanu will be confident now and will not do anything.
Abhi rings the bell. King sees him peeping inside. Abhi asks where is Pragya? King says not today and says today we will talk about your behavior which changes seeing Pragya. Abhi says I want to meet Pragya and says he will go to school and meet her. King asks him to forget Pragya and take her out of his heart. Abhi asks what happened? King says Chachi told me that you have feelings for Pragya, but I ignored her words and told that Abhishek is my friend and can't do this, but after whatever I have seen with my eyes, I have realized that you have feelings for Pragya.
Abhi says you are thinking wrong. King says when I kept my hand on her shoulder, you felt pain and when I was about to dance with her, you held her hand and took her to dance floor. He says it was cheap thing and asks him to say yes or no. he says Chachi saw you and Pragya together, but I said no, my friend can't do this. He says I didn't know that my friend comes to meet my wife at my house, and have soft feelings for her. Abhi says I am friend and about to tell…but King asks him to say yes or no, and asks him to say if he has feelings for Pragya. Abhi says yes.
He says she is so good that naturally feelings come out. King says Chachi was right, you are fixing Tarun and Neha's relation so that society restriction ends and you get a chance to get closer to her, so she was right, but whatever you are doing is cheap. Abhi says you are making fun of my feelings. King says you are making fun of my friendship and says you didn't think before eying at my wife. He asks him to get out. Abhi says you didn't know what we have between us. King says if I see you with Kiara or Pragya then…..
Abhi says truth is that neither Pragya is your wife nor kiara is your daughter, so you have no rights on them. King says you know the truth, but that doesn't matter to my family. He asks did you ask Pragya with whom she wants to live? He says Pragya is my wife and Kiara is my daughter in society's view. He says I love Pragya and will marry her soon, so that such people like you stay away from you. Abhi tries to tell him about their relation. King asks him to remember their enmity and tells that they will not talk other than Neha and Tarun's marriage. He says after their marriage, you will see Pragya and King's marriage and after that you will not take her name and will call her Mrs. Singh. King closes the door and goes inside. Abhi tells that she is his wife, but King doesn't hear him.
Disha waits for Abhi and thinks where is he? She calls Purab and asks about Abhi. Purab says I thought he is at home. Disha says may be he is with Di. Purab ends the call.
Pragya is at Kiara's school. Teacher asks him to sign the form and tells that all parents shall attend sports day. Pragya signs and gives the form. Teacher says you forgot to write father's name. Pragya thinks of Abhi and King and tells that if she can give the form later. Teacher says ok and goes. Pragya thinks to tell all truth to Abhi after Neha and Tarun's marriage to lower her heart.


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Last Thursday, per usual, I programmed Thursday's Thirst to be sent out at 8:15 a.m. and at that precise time I received notification that it had been sent. However, I quickly noticed that I had not received it and that very few people were opening it. A quick check found that it was not getting to most of the audience. I tried resending it an hour later, but received the same results. I waited until Monday, tried it again and ditto. In frustration I turned to Shane, my tech adviser, with the plea, "Please find what's wrong."
I was convinced that Mail Chimp was having technical difficulties, or that I was experiencing another problem with this new laptop. It did not take long for Shane to get back to me. He had found the problem, and the problem was ME!
Ouch! I was the cause of what I had been so quick to blame on others. And the problem I caused was beyond what I could fix … I could see the symptoms, but was clueless as to the cause. Reparations now in place (thanks, Shane), I am confident today's edition will be sent to all … And, in case you are interested, I intend to resend last week's one more time later today.
Technical difficulties are defined by Wikipedia as "unforeseen equipment problems such as hardware failures or software bugs that make it difficult or impossible to perform a desired action." What it took Shane to point out to me was something that Nathan pointed out to David long ago. David was his own problem then … I am my own problem now … and neither one of us could figure it out on our own! Thanks be to God who sends us "technical advisors" through whom he not only points out the problem, but actually solves it. It is only through the Holy Spirit working in us that we are able to say, "Have mercy on me, O God, according to your unfailing love; according to your great compassion blot out my transgressions. … For I know my transgressions, and my sin is always before me. … Surely I was sinful at birth, sinful from the time my mother conceived me." (Psalm 51.1-5)
The "technical problems" that make healthy relationships "difficult or impossible" for us are not found in computers … they are in us. And rather than just being minor glitches we can easily fix ourselves, our problems ultimately can only be solved by the Master Technician (and designer of the universe) … our Lord Jesus Christ. However, they are likely never to be resolved if we refuse to recognize them or keep blaming others.
Are you experiencing "technical difficulties" in any relationships these days? (If you think you are not, I suggest your re-read the previous paragraph). We have been given the prayer through which God solved the problem in David. It's one I continue to use every day, "Create in me a pure heart, O God, and renew a steadfast spirit within me. Do not cast me from your presence or take your Holy Spirit from me. Restore to me the joy of your salvation and grant me a willing spirit, to sustain me. Then I will teach transgressors your ways, so that sinners will turn back to you … Open my lips, Lord, and my mouth will declare your praise." (Psalm 51.10-15)
I sure hope this gets out to everyone today … and that God uses it to resolve many technical difficulties … starting with MINE.