text: Background 11-hydroxysteroid dehydrogenase 1 (11-HSD1) activates glucocorticoid locally in liver organ and extra fat tissues to aggravate metabolic symptoms. 14.56 and 11.92 M). Curcumin was A-966492 a competitive inhibitor of human being and rat 11-HSD1. Curcumin decreased serum blood sugar, cholesterol, triglyceride, low denseness lipoprotein amounts in high-fat-diet-induced obese rats. Four curcumin derivatives got higher potencies for Inhibition of 11-HSD1. One of these can be (1E,4E)-1,5-bis(thiophen-2-yl) penta-1,4-dien-3-one (substance 6), which got IC50 ideals of 93 and 184 nM for human being and rat 11-HSD1, respectively. Substance 6 didn't inhibit human being and rat kidney 11-HSD2 at 100 M. To conclude, curcumin works well for the treating metabolic symptoms and four book curcumin derivatives got high potencies for inhibition of human being 11-HSD1 with selectivity against 11-HSD2. Intro Glucocorticoids (GCs) possess an array of physiological and pharmacological tasks in mammalian features [1]. Extreme GCs under circumstances such as tension and Cushing's symptoms cause a spectral range of medical features, including metabolic symptoms [2]. GCs boost glucose result in the liver organ, induce fat build MEKK12 up, dampen glucose-dependent insulin level of sensitivity in the adipose cells, thus increasing the potential risks of metabolic symptoms [3]. Intracellular degrees of GCs (cortisol in the human being or corticosterone, CORT, in the rat) are controlled by 11-hydroxysteroid dehydrogenase (11-HSD), which includes two known isoforms: an NADP+/NADPH reliant 11-HSD1 oxidoreductase that behaves an initial reductase in the liver organ and fat cells (Fig. 1) and an NAD+ reliant 11-HSD2 [4], [5]. 11-HSD2 functions a unidirectional oxidase to avoid cortisol from stimulating the mineralocorticoid receptor in kidney and digestive tract, as well as the mutation of human being 11-HSD2 gene (plasmid A-966492 and transfection A manifestation plasmid was built to express human being 11-HSD1 (vector (pBluescriptSK+).[15]. The transformants holding an put in were chosen by colony hybridization, and a clone using the put in in the right orientation in accordance with the vector T7 promoter was determined by limitation mapping. A-966492 All transfections had been completed on 80% confluent ethnicities in 12-well plates. Aliquots of just one 1 g pcDNA I had been transfected into mammalian CHOP cells using the FuGENE Transfection Reagent (Roche) relating to manufacturer's process. Cells were permitted to grow every day and night in media including 10% fetal bovine serum. After that media were eliminated and cells had been gathered for 11-HSD1 activity assay. 11-HSD1 assay in undamaged rat Leydig cells and CHOP cells transfected with and adult rat testis as 11-HSD1 resources, we screened many nutraceuticals, including curcumin, icariin and berberine, and discovered that just curcumin (substance 1) demonstrated inhibitory results against human being and rat 11-HSD1, with IC50 ideals of 10.627.17 M and 4.180.24 M, respectively. In undamaged CHOP cells transfected with human being and adult rat Leydig cells, curcumin demonstrated inhibitory results against human being and rat 11-HSD1, with IC50 ideals of 5.782.22 M and 2.290.69 M, respectively, indicating that curcumin was slightly potent when the enzyme was assayed in intact cells. We further utilized undamaged cells to display curcumin derivatives (Fig. 2). Thiophenyl 1,4-pentadiene-3-one substances 4 and 6 had been being among the most powerful inhibitors (Desk 1 and Fig. 3). Substance 4 [(1E,4E)-1,5-bis(3-methylthiophen-2-yl) penta-1,4-dien-3-one] was 12.54 and 50.75 times stronger for the inhibition of human and rat 11-HSD1 activity than curcumin, respectively (Table 1). Substance 6 [(1E,4E)-1,5-bis(thiophen-2-yl) penta-1,4-dien-3-one] was 24.68 (human being) and 31.44 (rat) instances stronger than curcumin, respectively (Desk 1). There are obvious structure-activity reactions for these substances. Generally, the potencies of inhibiting 11-HSD1 activity for cyclic pentadienone analogues had been significantly decreased (Dining tables 1), indicating that the various constructions in the central spacer may are likely involved in the consequences of 11-HSD1. For instance, substance 9 [(1E,4E)-1,5-bis(3-methylthiophen-2-yl) cyclopentanone] didn't inhibit human being and rat 11-HSD1 at 100 M, and substance 16 [(1E,4E)-1,5-bis(thiophen-2-yl) cyclohexanone] inhibited human being 11-HSD1 activity with minimal strength (IC50?=?3.57 M) set alongside the open up chain pentadienone chemical substance A-966492 6, IC50?=?93 nM). There is also species-dependent inhibition, human being 11-HSD1 was even more sensitive to.


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Maddie's® Spayathon4PR HQHVSN Apprenticeship
Maddie's Spayathon4PR HQHVSN Apprenticeship with MSMP at Cornell
*Due to the COVID-19 pandemic, all Spayathon for Puerto Rico trips and programs are on pause.
Congratulations to the 5 applicants selected to participate in our Maddie's Spayathon4PR HQHVSN Apprenticeship program during ROUND 7 of Spayathon for Puerto Rico with Team Cornell in Mayaguez, Puerto Rico, in May 2020!
Leticia Arroyo, Animal Care Center of NYC (New York)
Rachel Bryan, Humane Society of Greater Savannah (Georgia)
Karina Fonseca, Humane Society for North Central Florida (Florida)
Brianna Marshall, Brother Wolf Animal Rescue (North Carolina)
Sarah Sperling, Altered Tails (Arizona)
How is the Maddie's Apprenticeship different from other Surgical Team volunteer positions on the team:
The Maddie's Spayathon4PR HQHVSN Apprenticeship is open to LVT and vet assistants employed by humane organizations or other animal welfare groups who have basic skills from working in a clinic, shelter, or medical program, but who would like a training experience specifically in a high-quality, high-volume spay neuter field clinic setting. Requirements include online training sessions before and after the clinic, reading and video-viewing assignments, and online quizzes. They will be assisting the surgical team by rotating through the various clinic areas, acting as assistants in receiving, induction, anesthesia, recovery, and discharge. They are funded through a $1500 stipend that is granted directly to their organization to help cover their expenses for participation in the clinic, including air and ground travel, lodging, and food. The apprenticeship is currently only offered through a grant to Cornell University's Maddie's Shelter Medicine Program at Cornell.
Surgical Team volunteers (DVM, LVT, Vet Assts, and Support) apply directly to Spayathon for Puerto Rico teams and are expected to be already highly skilled in HQHVSN and field settings. While they have a group meeting and orientation, they are expected to hit the ground running and not require training. They are reimbursed for travel costs after the clinic, and lodging is provided.
What is it all about:
The Maddie's Apprenticeship program will consist of three parts, ALL of which are mandatory:
- Preliminary online and remote training (to include reading material, online meetings, and written assignments) prior to the field clinic.
- Completion of a 9 day field Spayathon for Puerto Rico clinic, from set-up to breakdown, with 6 surgical days.
- A post training debriefing session and survey with clinic leadership.
There will be seven apprentice positions per clinic, and participants will rotate between induction, anesthesia/surgery, and recovery areas of the clinic over the course of the 6 clinic days. Apprentices will assist and be directly supervised by experienced licensed veterinary technicians and shelter veterinarians in all of their roles.
When does it happen:
Clinic dates for 2019 - 2020 are as follows. NOTE THESE ARE ACTUAL ON SITE CLINIC DATES and do not include travel the day before and after the clinic.
Round 5:
Clinic dates: October 31 - Nov 8, 2019
Round 6 (dates have changed):
- Clinic dates: February 21, 2020 - February 26, 2020
- Arrival date (travel): February 18, 2020
- Set up: February 19 & 20, 2020
- Tear down: February 27, 2020
- Departure date (travel): February 28, 2020
- Location: TBA
Round 7 (dates have changed):
- Clinic dates: May 1, 2020 - May 6, 2020
- Arrival date (travel): April 28, 2020
- Set up: April 29 & 30, 2020
- Tear down: May 7, 2020
- Departure date (travel): May 8, 2020
- Location; TBD
Round 8 (dates have changed):
- Clinic dates: November 6, 2020 - November 11, 2020
- Arrival date (travel):November 3, 2020
- Set up: November 4 & 5, 2020
- Tear down: November 12, 2020
- Departure date (travel): November 13, 2020
- Location: TBD
Each organization sending an apprentice will receive $1500 to support travel and lodging for the participant. Apprentices will work with their organization to use these funds to book travel, rent an "apprenticeship team" minivan for ground transportation during the clinic, rent shared housing with the other apprentices through Airbnb or other service, and cover additional costs. MSMP leadership can help coordinate these activities with the rest of the surgical team. One apprentice will be named as Captain and Overlord of the Apprenticeship Squad for each clinic to help coordinate these activities for the apprenticeship team in collaboration with the Maddie's Shelter Medicine Program (MSMP) leadership. Funds remaining are the organization's to use in implementation of related programs.
Physical requirements:
Candidate must have the ability to meet the physical demands of the position, which include, but are not limited to, stressful situations, prolonged standing and kneeling, warm environmental conditions, and lifting and restraining animals that may exceed 50 pounds. Clinics open at 6am and often don't end until after 6pm. You also should read the CDC's recommendations for travel to Puerto Rico in terms of medical risks and preventive care prior to applying. https://wwwnc.cdc.gov/travel/destinations/traveler/none/puerto-rico
Please complete and submit the form that can be found by clicking on the link below.
Application link: https://forms.gle/ucU6BjMyTB41MLxF6
*Notification of Acceptance: Applications will be reviewed and selected team members contacted with notice of their award by 6 weeks prior to the date of the clinic.

subset: commoncrawl


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Social media is the necessity of every business in today's world. More and more people are now connected through social media platforms. Social media platforms like Facebook, YouTube, Snapchat, and Instagram have millions of users worldwide.
Due to a large number of users on every social media platform, most businesses have created their social media accounts. Businesses can build a brand image and find their identity among competitors by utilizing social media platforms. Let us explore the top 5 social media marketing strategies.
Table of Contents
Creating Content To Engage Users
The first step in using social media platforms to grow your business is to engage your users. To engage your users, you need to create and publish content regularly on your social media accounts. You should create useful and informative content for your users. However, before creating content, you should know your target audience and study what type of content they want.
Most brands run some contest and quiz to engage their users on their social media accounts. Once you know the interest of your target audience, you can create informative content around their interest and publish on your social media accounts.
Run Paid Ads For Brand Awareness
Businesses run paid ads to create brand awareness and generate leads. In order to generate leads, you need to follow relevant marketing strategies to show the right products to potential customers. You need to target the right audience, because if you target wrong people using paid ads, you may not generate leads for your products. If you target the right people interested in your product or service, you are sure to generate decent leads.
Run Effective Campaigns To Drive Traffic
You need to develop effective campaigns to drive traffic to your website and cater to your customers' requirements. As a social media marketer, you should structure your campaign according to your target audience. You should research the latest trends followed by your audience and create a marketing strategy around them.
Use The Right Hashtags & Keywords
Social media marketers need to use the right hashtags and keywords in their posts. You need to research and find the right hashtags and keywords to use them in your posts on social media platforms. By determining the frequency of posts related to the selected hashtags, you can check which hashtag is used the most. You can also use the same for your future posts.
Another great way to use your brand name as the hashtag in your social media posts. You can also use keywords especially made for some marketing campaigns. Use trending hashtags for the current season to get more customers to reach out to you.
Have Relevant Landing Pages
Landing pages are essential for every business to capture leads. You should have a well-designed landing page where your customers can buy your product or service after getting redirected from social media. Also, you need to have a call to action option that your customers can select to subscribe to you or make a buying decision. You can provide your visitors with a registration form, newsletter, free trial, or a call back from your business.
Social media marketing is a journey where a business needs to learn to apply continuously. All the strategies change with time. What works today on a platform may not work after a year or two. You need to continuously research what works in the present scenario and what not to create your marketing strategy accordingly. You also need to keep yourself informed about the latest trends of social media platforms and post regular content on them. You can also hire a reputed social media marketing agency like https://www.injader.com to run your social media campaigns and generate leads for your business.


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Kidney cancer develops most often in people over the age of 60, and is more common in cisgender men than in women, and in African American, Native American and Alaskan Native populations. An exact cause of the disease remains unknown, however people with the following risk factors are more likely than others to develop kidney cancer:
- Smoking. Smokers are twice as likely as nonsmokers to develop kidney cancer.
- Obesity
- High blood pressure
- Advanced kidney disease. People with advanced kidney disease that requires long-term dialysis have increased risk for developing kidney cancer.
- Von Hippel-Lindau (VHL) syndrome and other hereditary kidney cancer genes. VHL is the most common cause of hereditary kidney cancer. This rare genetic disease is caused by changes in the VHL gene that can be inherited. An abnormal VHL gene can lead to multiple tumors or cysts of the eye, brain, pancreas, adrenal gland, kidney and other parts of the body. If you or a relative have a known VHL gene mutation, talk to your doctor about tests you should have for early detection of kidney cancer and other cancers.
- Family history. Your risk of kidney cancer is increased if you have a relative diagnosed with kidney cancer. People with a family history of renal cell cancer are 2 to 4 times more likely to develop the disease. If you have kidney cancer and also a family member with kidney cancer, or if your kidney cancer diagnosis occurs by age 46 or younger, you may want to pursue genetic screening for hereditary kidney cancer syndromes (such as VHL, HLRCC, HPRCC, BHD and others) to better assess your kidney cancer risk.
- Occupations that involve exposure to certain chemicals or substances in the workplace. These include coke oven workers in the iron and steel industries and exposure to asbestos or cadmium on the job.
- Gender. Those assigned male at birth are more likely than women to be diagnosed with kidney cancer.


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Yeast transforms sugars in the wort to C02 and alcohol. Yeast comes in liquid and dry form for the homebrewers use. There are multiple liquid yeasts around to suit each type of beer.
Liquid yeasts are on the whole considered to be better than dry yeasts. Each liquid yeast adds its own unique flavour to the brew. Nonetheless, liquid yeasts are about five times as expensive as dried yeasts. Hence, dried yeasts end up being more commonly used. There are excellent types of dried yeast available, such as, Gervin, Danstar and Safale yeasts, all providing wonderful results.
Yeast transforms sugar into alcohol. There are many kinds of yeast; however, just a few are suitable for brewing. The strain of yeast you use is a crucial determinant with regard to the finished beer's flavour.
This is the case because the yeast's by-products, as it converts sugar to alcohol, supply most the beer's flavour. Hence, it is vital to pamper the yeast whilst it is working by ensuring that the brew is at the correct temperature. Should the yeast be too hot, there is the production of too many flavour compounds. Should the yeast be too cold, the beer can taste pretty bland.
There are numerous types of dried yeast available. Gervin English Ale Yeast is good. Liquid yeast cultures are great too, like Whitelabs and Wyeast products. They are on the market at around £5 and necessitate you doing more work. You can, however, reuse them. The resultant quality of beer makes these liquid yeast cultures well worthwhile.


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A new type of quantum holography that uses entangled photons to overcome the limitations of conventional holographic approaches could lead to improved medical imaging and speed the advance of quantum information science.
A team of physicists from the University of Glasgow is the first in the world to find a way to use quantum-entangled photons to encode information in a hologram.
The holograph is created by measuring the differences in the light's phase where the two beams meet. The phase is the amount that the waves of the subject and object beams mingle and interfere with each other, a process enabled by a property of light known as 'coherence."
The Glasgow team's new quantum holography process also uses a beam of laser light split into two paths, but, unlike in classical holography, the beams are never reunited. Instead, the process harnesses the unique properties of quantum entanglement—a process Einstein famously called 'spooky action at a distance' – to gather the coherence information required to construct a holograph even though the beams are forever parted.
Source: Phys.org


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I can remember as it would have been yesterday, not long ago an experimental undertaking, influencer marketing has rapidly matured, making the transition to the digital marketing mainstream as a go-to strategy. There is no marketer not planning it into there marketing mix.
Based on this comparison between money spent on sponsored posts and Stories on Instagram in Q1 2019 and Q1 2020, it is estimated that Instagram's influencer marketing market size will reach between $5 billion to $6.5 billion in 2020.
But let us hold back a second and look into some details, things you must know about influencer marketing in 2020.
What to know about Influencer
Their top concern is authenticity and compliance and key to present a brand or product.
- 99% of influencers say they only work with brands they believe in and who share their values together.
- 61% prefer monetary compensation over all other types of collaboration arrangments.
- 85% report buying followers as their top compliance concern within the industry.
What you should know about social networks
Instagram is still leading the pack and is absolute leader in influencer marketing.
- More than 75% of influencers of all genders rank the platform as their favorite.
- Influencer considers stories, posts and IGTV as the top 3 content formats with the most potential in the next 6-12 months.
- Instagram influencer marketing is key to social commerce's growth: 42% of fashion influencers have already made a purchase on the platform.
- Following the footsteps of Instagram, TikTok is expected to become a major player in the influencer space with 41% of users aged 16-24.
Are you a marketer? If not so and you are maybe you are an influencer or want to be one then know the following.
What you should know about the marketers
The see influencer marketing as an integral part of their all-over marketing strategy.
- 84% believe that influencer marketing is effective at connecting with consumers on social media.
- 90% plan to increase or maintain their influencer marketing budgets.
- The overall formula to obtain the best ROI: Influencer marketing + SEO + Social Ads
For marketers scaling up their investment in 2020 as well as those initiating their influencer activity just now, it's vital to get an accurate picture of the territory as it stands today.
Below, in the infographics from the influencer marketing platform SocialPubli which shows it in a compact way.


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These days a lot of places have more ideas about how to support workforce development initiatives than funding to make them happen. A few months ago I met Telly Tucker of Discover Danville (Virginia) and heard about how one of their creative solutions. Some years ago they sold a community owned hospital and used the proceeds to start a community foundation. Since that time, the foundation has placed career and student success coaches in area schools and funded a range of scholarships for local children. That's the short version, of course, you can read more here: http://www.cfdrr.org/.
Going forward, I think it the places that get creative and find ways to fund economic and workforce development outside the usual channels will have the flexibility and the reach to execute on initiatives that might otherwise never make it off the page of planning documents. That made Danville, Virginia a place I'll remember.


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Everyone needs a "pep talk" to find encouragement once in a while. Today, I'm sharing a video made six years ago by a team of brothers, in which one went by the title "kid president."
Kid president shares many ideas here that are sure to delight you, encourage you, and possibly make you smile. I hope you will enjoy this flashback as a fresh voice to lift you today.
As you jump into the day today, don't forget to make the world just a little "more awesome."


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Can/Does MailEnable (Ent) WEBMAIL show the 'Conversation threads' (or replied to links) ??
I can see the little green arrow on the white envelope when an email has been replied to . . but clicking this opens the email and not the reply (which is in the sent-items folder).
Is there an easy way to see/find the reply for any email that has been replied to (without needing to sort through the sent-items folder) ?
Cheers, Stephen Davey


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Visitors to Spirit of Speyside: Distilled, which returns to Elgin's town hall after a hugely successful inaugural year, will be among the first to sample two new gins and a collaboration between a small craft brewery and one of the world's best-selling single malts.
Running over Friday the 1st and Saturday the 2nd September, tickets for the festival have been selling at a brisk pace, the organisers say, and give people access to over 30 exhibitors showcasing spirits, beer and food, along with food and drink venues serving their own special cocktails and Speyside snacks.
The first of the new product launches will be Avva Scottish Gin, who are launching a new limited edition expression, created to celebrate Spirit of Speyside: Distilled.
The locally produced gin, which is also bottled in Elgin, will be available to buy in very small quantities. Distiller Jill Brown, who launched the Avva brand last year, will also be telling the story of her products at one of the festival masterclasses.
Husband and wife team Bob and Silvi Duncan have also chosen the event to launch a new brand of fine artisan spirits. The couple, who are behind Duncan's Spirits, will be giving gin-lovers a chance to taste their first batch of Duncan's Gin.
The Duncans say they have put the Speyside region at the very heart of their new product, which contains the freshest Highland juniper with five other foraged and handpicked local Scottish botanicals.
The result is a gin which they feel reflects the "very essence and flavours of the Speyside landscape through its freshness and simplicity".
The festival has also been chosen as a platform to showcase a new experimental IPA – an incredible collaboration between the Speyside Craft Brewery and Glenfiddich Distillery.
Glenfiddich IPA Finish is being launched later this autumn, but organisers say that those who go along to the festival will have an exclusive opportunity to taste it before it goes to market.
Spirit of Speyside: Distilled is a sister event of the Spirit of Speyside Whisky Festival, which has been running for almost 20 years. Organisers see it as an opportunity to highlight the region's world-class food and drink producers, in addition to whisky distillers.
Event chairman James Campbell said: "We are honoured that we will have three different product launches taking place over the two days of Spirit of Speyside: Distilled.
"I think this underlines that the producers already see this event as a very important one in terms of the profile it brings, which is very encouraging given that this is only its second year.
"The producers are genuinely interested to learn what Spirit of Speyside: Distilled visitors have to say about their products. Many of them are very passionate and knowledgeable about food and drink, while others simply enjoy it for what it is – either way they are the people who go out and buy these products so it's important to get feedback from them.
"Tickets have been selling online very quickly in these last few days leading up to the event, but we will be holding some tickets back to sell on the door. We don't want anyone to miss out on this fantastic opportunity to sample Speyside's food and drink and to meet the people at the very heart of the industry."
Sponsored by Bruce Stevenson Insurance Brokers, the two day event will run over four different sessions, one from 1-5pm and one from 6-10pm on both days.
Tickets are priced at £20 which includes entry, six vouchers for tasting samples of gin, whisky or beer, a lanyard and a Glencairn crystal nosing and tasting glass. Tickets can be booked here.


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Liam Cyber Gets Off On August Alexander's Feet
Liam Cyber is always ready for more sock smelling and foot worship at any time. Just the smell of August Alexander's socks make Liam hard! When these two guys get hard you better get out of the way because it gets crowded. Liam continues to worship August's socks and then puts his tongue between each of his bare toes like the toe-sucking expert he is. Both men blow a load during this impromptu foot sex session enjoying and exploring their male foot fetish.


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I'm so excited to have a new class to share! I love the Maggie Holmes Garden Party collection that just arrived for spring and couldn't wait to play with it and come up with a new class. Here we are!
There are so many different options for the front cover of the album, but I settled on this simple combination of embellishments. I love the layered paper flower stickers that come in the class kit!
Inside the new Heidi Swapp Decades album are two premade notebooks, but we'll take them apart and use the notebook papers and the beautiful printed papers to make new pages for four notebooks to fill the album. How sweet is the sticker inside the Tim Holtz frame?! Love the birdie peeking over a page, too.
The bunny charm is flipped around but the charms from the tassels in the kit are perfect for hanging off the edge of pages. The kit comes with two tassels from a package of four.
Here are the covers of the four notebooks we'll make for the album. They are filled with flaps and foldouts and pockets - all the things I like for making your book interactive.
I'm including ten matching greeting cards in the class kit, and we'll be using some of them in our notebooks like this one here...
I'll be teaching the class on Zoom live on Sunday, May 23, and on Saturday, June 26, and I'll be adding an August date very soon. If you know that you won't be able to attend any of the live Zoom classes, you can also purchase the kit and the recording of the class without committing to the live class. You can read all about the class, including more specific information about the class kit and times of class, etc. here: Garden Party Album, and you can sign up here: The Memory Bee Online Shop.
I'm working on another new class with the Simple Stories Safe Travels collection in an Echo Park navy blue traveler's notebook - it's super cute! I'll also be offering a little boy and girl album classes using the Echo Park Little Dreamer collections in new 4x4" We R Memorykeepers albums. They are on order but haven't shipped yet. Fun things ahead!
You can still sign up for my Jello Books class in my online store and can read about it HERE. I've been making more books - I just can't stop myself! and will share them here later this week. This class is only $22 - I think you'll get addicted, too!
Have a great day and I hope to see you in class! It's so much fun to catch up! Love, Debby xoxo


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Maharshi Dayanand Saraswati Quotes
Maharshi Dayanand Saraswati was the founder of Arya Samaj and also a social reformer, freedom fighter, and great thinker of Modern India. He was an ideal Arya, a unique personality with a blend of qualities that make a man truly great the rarest of the rare. A scholar has said – "He was a happy blend of Ram and Krishna, Buddha and Christ, Shankar and Mohammad."
He was born on the tenth day of the waning moon in the month of Purnimanta Phalguna (February or March) which is celebrated as Maharshi Dayanand Saraswati Jayanti. Maharshi Dayanand Saraswati Jayanti 2024 will fall on Tuesday, March 5th. Share our Swami Dayanand Saraswati images and quotes with your friends on his Jayanti.
People should never worship images. The spread of mental darkness is due to the prevalence of idolatry.
In life, a loss is inevitable. Everyone knows this, yet in the core of most people it remains deeply denied – 'This should not happen to me.' It is for this reason that loss is the most difficult challenge one has to face as a human being.
The soul is one in its nature, but its entities are many.
He is good and wise who always speaks the truth, acts on the dictates of virtue, and tries to make others good and happy.
There is no verb for compassion, but you have an adverb for compassion. That's interesting to me. You act compassionately. But then, how to act compassionately if you don't have compassion? That is where you fake. You fake it and make it. This is the mantra of the United States of America.
The people of our country do not know the value of time. It's difficult for them to work under discipline from morning to evening, their all worked is disturbed, wastage of time is a cause of downfall in our country.
Beneficence removes evils, introduces the practice of virtue, and adds to general welfare and civilization.
The main aim of education is to create human awareness so that they can understand the difference between the truth and the untruth. Even by understanding if anyone does not practice it he is like a thief.
The tongue should express what is in the heart.
When one Arya is alone he should do self-reading when two they should discuss and ask question answers within themselves when more than two then they should do Satsang and read any chapter of Vedas.
Mother, father, and teacher are best guides of a person, that person is real lucky whose parents are virtuous as they will always guide him to the right way and always thinks good for him.
To keep yourself pure remain alone, never see bad, never hear bad, never stare at girls, never learn bad, be punctual and obey rules. By practicing these you can achieve self-control and purity.
I consider almighty god above all so only I always propagate his true message of Vedas.
As the god has given sun, water, earth, fire, air, moon to all. In the same way, he had given true knowledge of Vedas for all mankind.
When bad does not leave their badness why does the good leave their goodness.
Even if people burn my fingers by burning them as candlesticks then even I will never deviate from the path of saying the truth.
As breathing is necessary for us daily, in the same way, practicing yoga, praying to god, reading Vedas and agnihotra is necessary and should be done daily.
If all people understand the true dharma given in Vedas then it's definite that all would definitely be benefited.


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Social intranet / Digital Workplace for Healthcare
How to ensure that all employees in the organization search, find and share the right information in a central place? And how to reach potential employees or relatives as an important target group? We are a&m impact and with almost 25 years of expertise in digital communication for healthcare, we offer unique and user-friendly solutions to these challenges.
Our social intranets, websites and portals have been specially developed for and by healthcare professionals. Tickets, incidents, reservations and knowledge items from TOPdesk can be easily made available to employees, volunteers and external parties on our social intranet and portal. They do not have to worry about double logins, security, up-to-dateness and integration.
All our communication solutions can be easily linked together. This makes a duplication of work no longer necessary. Due to our critical view on security (ISO 27001 and NEN7510), all data is in a safe place. Our applications are available on all devices. We work for more than 100 healthcare organizations and have 200.000+ users. We are located in Doetinchem, the Netherlands.
How does it work you may ask?
Please watch our video. Tom is happy to take you through the social intranet of a&m impact. Specially made for and by healthcare. Note: the video is in Dutch.
Please visit our website to read more about social intranet.


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On the surface, I would go to the same place that I went with Kansas.
Iowa State is not very good offensively.
Less yards per game, both rushing and passing, than Kansas.
More turnovers per game than Kansas. More interceptions per game than Kansas.
But yet here they sit at 4-2. Granted, they are 1-2 in the conference, but all three of those games are against "quality" opponents.
A loss to Tech
- 4 Cyclone turnovers and less than 200 yards of total offense;
A win over TCU
- Horned Frogs' first game without veteran QB Pachall
- 5 TCU turnovers
- The Cyclones were to TCU what Arizona was to OSU...outgained by the opponent, but TCU mistakes turned things in Iowa State's favor
A loss to undefeated Kansas State
- Kansas State essentially played keep away...40 - 20 edge in TOP
- Iowa State did have the ball at the end with a chance to win, but got stuffed near their own goal line;
What does this necessarily tell us? Not a whole helluva lot, as the Big 12 doesn't really know who it is this season.
So about the only thing I can say is this...
If the Cyclone defense can keep OSU's offense from blowing the game open, their offense is good enough to win the game against the Cowboys' "4th quarter" defense.
For proper comparison, and since there is now a large enough sample size, I'll focus on conference games only.
Against Tech, TCU, and KState, Iowa State averaged
- 23.6 ppg...however, take away 2 interception returns for TD and that drops to 19.0 ppg for the offense;
- 257 ypg on 58 plays...4.43 yds/play
- 97 ypg rushing...32 attempts at 3.03 ypc...While both Jantz and Barnett are mobile, they are not going to put up Colin Klein stats. They will, however, keep the play alive. James White, Shontrelle Johnson, and the QB carry the load with 27 carries for 90 yards per game. White, who was averaging over 5 ypc, logged no carries against KState, so he may be working on an injury. Barnett averages over 4 ypc.
- 160 ypg passing...13 of 26...6.15 ypa...Passing attempts have gone down with Barnett at the helm, and consequently rushing attempts have gone up, relative to the average above...22/35 pass to rush against TCU...20/40 against KState
Hard to tell who the receiving threat is with only 13 completions per game. The yardage leader is Josh Lenz, who had a HUGE game against TCU (5-147 & 3 TD's), but had only 2 catches against Tech and none against Kansas State. Aaron Horne leads in receptions (10), but did virtually nothing against Tech & TCU before going 7-84 against KState. Ernst Brun Jr at TE has been the most consistent, logging 2-3 catches per game for about 30 yards. RB screens are obviously a part of the scheme. - 5 penalties for 42 yards
- almost 3 turnovers per game (1 fum/2 int), but most of that was against Tech. With Barnett getting the bulk of the snaps in the last two games, the Cyclones have only turned the ball over once in each (interceptions), which is very interesting. Jantz is the more accurate QB in completions, but has a higher int/att ratio.
- 4-13 on 3rd downs
- 22:51 in TOP
- 11.6 possessions per game
- Scoring by quarter...excluding defensive scores
Odd stats from those 3 games that might apply to OSU's defense:
- Have not scored a single point offensively on any drive that STARTED in the 4th quarter;
- Average 2 possessions in the 4th quarter (excluding end of half possessions);
- Average 5 plays per possession
- Here's all the Cyclone possessions that originated in the 4th quarter from the last 3 games
PLAYS YARDS RESULT 9 26 Fumble 6 30 Interception 4 6 Turnover on Downs 4 5 Turnover on Downs 3 3 Interception 3 5 Punt - On 35 possessions in those 3 games, the Cyclones averaged 4.8 plays and 22.7 yds per possession;
- 54% of those possessions (19) have been 3 plays or less
-13 were 3 and out
-5 ended in turnovers
-1 ended in a TD - Only 8 possessions of 7 or more plays
-75% (6) of those drives resulted in points, 5 of those were TD's;
- all but one of those drives started in either the 1st or 3rd quarters;


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A better day starts with an Aurora night.
A company founded on the dream of better sleep for everyone.
Since 1993, Aurora Sleep Products has been providing a dream-inducing balance of lavish comfort and luxurious support - the perfect combination for a rejuvenating night's sleep. And as more and more research shows, the perfect night's sleep can lead to increased energy levels, improved health and improved overall wellness.
That's why our world revolves around the concept of better sleep. In fact, our company was literally founded upon this guiding principle. It all started when a couple moved to Central Florida back in 1993. The wife shopped for pillows, but was losing sleep over the fact that she simply could not find a good pillow. She thought . . . why buy a pillow you're not happy with when you can make your own-and make it better! So, the company was born and sales flourished.
Aurora Sleep Products was appropriately named after the cherished sleeping beauty character (Aurora) from the classic children's fairy tale. You might say we believe in sleeping happily ever after.
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Aurora provides specially-designed pillows and sleep products for hotels, resorts, cruise lines, yachts, furniture stores, sleep shops, interior designers/work rooms, hospitals and medical industry, nursing homes, and even college dorms. With Aurora, customers can rest easy knowing they will receive the highest level of comfort, quality, personalized service and value.
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Emulsified vitamin D WisdOM-3 is a proprietary emulsification process which improves overall taste for increased patient compliance Easy-to-use Can be dropped directly in the mouth or mixed in drinks Citrus-flavoured Great taste for excellent patient compliance D-mulsion is emulsified vitamin D using the unique WisdOM-3 process which minimizes bile dependency. It uses lanolin as a precursor, and a base of extra virgin olive oil. Vitamin D helps in the development and maintenance of bones and teeth.*
Suggested Use
Recommended Dose (All Ages): Take one drop daily, or as recommended by your health care practitioner.
Dietary Considerations
Wheat Free Dairy/ Milk Free Gluten Free Vegetarian Yeast Free Sugar Free Corn Free Free of Artificial Colors/Flavors
Product Info
Serving Size: 1 Drop Servings Per Container: 1200 Disclaimer Amount Per Serving Vitamin D (cholecalciferol) 1000 IU Other ingredients: Stevia (Stevia rebaudiana) Leaf Std. Extract (90% Stevioside), Purified water, Maltodextrin, Modified tapioca starch, Extra virgin olive oil, Lemon oil, Microcrystalline cellulose, Sodium carboxymethylcellulose, Citric acid, Potassium sorbate, Natural mixed tocopherols
Guaranteed to contain no added wheat, yeast, gluten, corn, sugar, artificial coloring or flavoring or dairy products. Ideal for vegetarians. Quality Assurance Tamper-resistant package. Do not use if outer seal is missing or broken. Store in a cool, dry place.
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Payment methods
Your payment information is processed securely. We do not store credit card details nor have access to your credit card information.
Required Notice For California Residents: California Proposition 65 WARNING: Consuming this product can expose you to chemicals including lead which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov/food.


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Porvair Filtration has introduced an in-process, product validation service for its range of polymeric cartridge filters for use within the pharmaceutical industry.
The range of polymeric cartridge filters from Porvair Filtration is used across many markets including biopharmaceuticals, food and beverage, industrial and chemical process.
However, process validation of cartridge filters, specific to a product is mandatory within the pharmaceutical industry to ensure compliance with standards set by regulatory authorities including the United States FDA, European Pharmacopeia and ISO 13408-2.
Porvair's sterile filter range is already validated to remove bacteria in accordance with the recommendations of leading regulatory and advisory bodies such as HIMA, PDA and ASTM.
A detailed validation guide for each product lists the tests undertaken to ensure bacterial retention and USP VI compliance.
However, standardised tests do not reflect actual process conditions, the company claims.
Ingredients used in the manufacture of pharmaceuticals, such as solvents and oils, can degrade filter cartridges; resulting in unacceptably high levels of leachables and extractables, or a compromise in product sterility.
Porvair Filtration, in collaboration with leading FDA approved laboratories, is offering to undertake independent testing for chemical compatibility, extractables, leachables, and bacterial retention.
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The Eagle Flies
About the only appealing aspect of the Steelers 3rd Pre-Season Game last night in Philadelphia, were the Eagles Cheerleaders. The rest of the action on the screen was very difficult to watch, unless of course you are an Eagles fan. The performance by the Steelers first team Offense and Defensive was very reminiscent of last years teams, the Defense couldn't get off the field, giving up long drives resulting in touchdowns, and the Offense just stumbled and bumbled around. The Defense in recent years has been described as old and slow, after much investment in making it young and fast, it is still a moveable object that opponents have very little difficulty in pushing and shoving around. The Eagles Nick Foles led offense came out in a no huddle, uptempo mode. Foles lead the team right down the field on first three drives, resulting in two touchdowns and a field goal. The drives were of 80 yards, 77 yards, and 50 yards respectively. Steeler fans have to be scratching their collective heads, we have a total of 5 first round picks starting on Defense, second year Jarvis Jones and brand new phenom Ryan Shazier, as well as second round upstart Stephon Tuitt. After all the free agent additions, the collective draft picks, OTA's, a full training camp, and what looked like a successful start to "Team Development" as Coach Tomlin likes to say, this was the best product he could put on the field?
What is most troubling, is that the same issues and deficiencies are still nagging this team. Pour tacking, soft coverage, no pressure, missed assignments, and the most glaring problem, stopping teams on third down. Is the problem Dick Lebeau you might ask? That certainly is the one constant throughout all the personnel changes and upgrades, has the game past him by? Has Coach Tomlin lost his ability to motivate and prepare his team? The latter being true as the blame surely needs to fall on the person in charge, but what is the problem exactly and how can it be corrected? Some of you may by saying, it's only pre-season, we'll get better. However, how much confidence can you gain from that statement. Until we finally see sound execution on a consistent basis, there's no reason to think things have changed.
Offensive Struggles
Conventional wisdom would point to the recent arrests of running backs Le'Veon Bell and LaGarrette Blount as the primary reason the team was out of sorts, and there is certainly some merit to that. Watching the Steelers Offense flounder and flail about, you can only imagine what must have really been on the minds of Bells teammates. But why was Big Ben so scattershot? Overthrowing his receivers, making poor decisions, a complete lack of leadership and cohesion. Everyone was in a funk, totally lethargic and meek. The bottom line moving forward is this, there has to be something more going on in the passing game than Antonio Brown and Heath Miller. Newly acquired slot receiver Lance Moore didn't dress and hasn't shown much in the way of impact. His blocking last week was less than stellar and no apparent chemistry between him and Big Ben has been displayed. Free agent Darius Heyward-Bey has seen limited action, but looks as if he will beat out rookie incumbent Martavis Bryant if the choice comes down between the two. Where is Justin Brown? Should a pass or two not been thrown his way last night, if not just for shits and giggles.
Second, Third Teams
There was a clear stage set for rookie wide receiver Martavis Bryant to earn his stripes last night, however it may be safe to say he showed his true colors instead. There were high hopes for the 6′ 5″ former Clemson receiver, however it looks like he's not adapting to NFL competition. Bryant has shown trouble consistently handling coverages, whereas in College he had a keen sense for the ball, he now is far too occupied with beating the corners he's up against. Receivers have to be physical, there is a lot that goes into running routes, field awareness, separation, then of course eying the ball. The Steelers made a concerted effort towards giving him opportunities on a variety of routes, including a fade route from the red zone. Bryant failed miserably, he just doesn't seem to have the toughness or concentration, the majority of the passes thrown his way throughout this pre-season should have been caught.
Conversely, the efforts by slash sensation Dri Archer have been consistent and promising. Archer has been a guy who is showing not only that he can play in the NFL, but can be productive. A true bright spot throughout, showing again last night that he is someone that will work hard and can be relied on. Speaking of someone we can rely on, what is going on with Sean Suisham? A missed 46 yard field goal last night to go along with one in the first game against the Giants, last week he missed an extra point. Suisham only missed two attempts all of last year, he's already 3 in the hole in exhibition play. Hard to say how significant that will be this season, if the Defense continues to allow high scores, game winning field goals may not be necessary. Perhaps money is the root of all evil, how many players have you seen deteriorate right after they cash their check.
All the sudden the September 9, opener against Cleveland doesn't look like a cake walk. Furthermore going into Baltimore 0-1 would not be a very comfortable feeling, 0-2 facing the Panthers in week 3, well, you can do the math. Of course it's only pre-season right, it doesn't mean anything in the grand scheme of things, right? You say these problems will be all fixed, everything ironed out and raring to go. We'll soon know, but looking into the reflection of last years ills is troubling to say the least. This team has it's work cut out … Next up, cutting the roster down.


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Direct Shipping means you will ship the item directly to your buyer, rather than to Vestiaire Collective for quality control checks and authentication.
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How to play 'Halo' on your iPhone or iPad with Microsoft's Project xCloud
Project xCloud is the codename for Microsoft's new game streaming service, and it is now available in beta for users to test out, bringing massively popular titles like "Halo - The Master Chief Collection" to the iPhone and iPad. We've spent a few hours playing to test it out.
Microsoft has just started public testing Project xCloud on iOS and iPadOS, which means that this is heavily in beta territory. So as we tested it out, the lag, text overlays, or other idiosyncrasies can for the moment be blamed on its TestFlight status rather than any real issues with the app itself. Fortunately, bugs we did see were few and far between.
You need at least 10Mbps internet speed via cellular or 5GHz Wi-Fi. For our time using it we relied on a gigabit Wi-Fi 6 network on our iPhone 11 Pro Max. More than enough to ensure that our internet connection isn't to blame for any playback issues.
Playing Halo on iPhone
To get going and start playing, you also need the Project xCloud app, a Microsoft account, and of course an Xbox controller.
If you want additional information on using controllers with iOS and iPadOS, we did a more in-depth look at what the requirements are and how they work. For the sake of brevity, the important part you need to know is how to pair the controller.
To do so, press the connect button on the front of the controller until it starts to blink rapidly, then find it in the Bluetooth settings on your iPhone or iPad.
We then were able to jump into the Project xCloud app and choose "Halo - The MasterChief Collection." The game goes straight to the main menu, just as it would on your Xbox console.
While we gamed, the experience felt very smooth and natural — not at all like we were streaming the entire game. Occasionally we saw a small amount of lag, but nothing that was a dealbreaker and this will hopefully be corrected post-beta.
Most of our testing was done by playing social online multiplayer matches using our iPhone, though of course this all works on our iPad Pro as well.
A promising proposition
Apple Arcade is a great option for casual players, but Project xCloud is something more and brings much more substantial titles to mobile.
Streaming gaming is clearly going to become more prominent going forward. It allows you to play games that aren't necessarily available on a platform and reduces the need to download massive game files before playing.
Project xCloud isn't the only game streaming service around. Steam Link allows you to play PC titles on your iPhone, iPad, or Apple TV. GeForce NOW brings many Windows-only titles to the Mac. And now we have Project xCloud that brings many Xbox titles to iPhones and iPads.
While in beta, Microsoft is only testing with "Halo - The MasterChief Collection" but upon launch, many more will be available. That includes "Tekken 7," "Madden 20," "Devil May Cry 5," "Borderlands 3," "Gears 5" and plenty more. Be sure to visit the Project xCloud site for the full list of current titles.
If you'd like to sign up to try to nab a spot in the current beta, head over to the streaming service's website to learn more.


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The two SK Group units have participated in a Series D funding round for Cala, the leader in non-invasive bioelectronic therapy via a wearable device that is proven to reduce essential tremors. SK Biopharmaceuticals said the investment in Cala will pave the way for further strategic partnership and investment in the largest biotech and healthcare market.
SK Biopharmaceuticals has focused on the development of treatments for central nervous system disorders including epilepsy. The company said its strategic partnership with Cala would open up the potential to explore solutions for new indications in neurology and become a "stepping stone" to drive innovation in patient access and care.
"We are excited to forge a strategic partnership with Cala Health in bioelectronic medicine, and further support our common goal of spurring innovation and improving patients' lives," SK Biopharmaceuticals CEO Cho Jeong-woo said in a statement on May 19.
SK Biopharmaceuticals is developing a digital therapeutic device that can detect seizures for patients with epilepsy. Digital treatments are software and devices that directly prevent, manage, and treat diseases using digital technology. They enable personalized treatment for patients using AI and big data technologies, and have a low risk of side effects.
Cala's wearable neuromodulation therapies merge innovations in neuroscience and technology to deliver individualized peripheral nerve stimulation, and its vertically integrated commercial model is reshaping the delivery of prescription therapies. "Together, we will accelerate the realization of our joint mission of developing treatments and driving innovation to help more patients struggling with neurologic disorders," said Cala CEO Renee Ryan.
© Aju Business Daily & www.ajunews.com Copyright: All materials on this site may not be reproduced, distributed, transmitted, displayed, published or broadcast without the authorization from the Aju News Corporation.


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DIY Reclaimed Wood Stool + Plans
Build your own reclaimed wood stool following these DIY wooden stool plans! This simple farmhouse DIY step stool is great to help reach things or to use as an ottoman or plant stand, too.
See more reclaimed wood projects here, and build a simple flip-over barstool step ladder or a DIY ladder chair, too.
Simple DIY Wooden Stool
Hi friends! It is Mindi from MyLove2Create. Today I am excited to share my latest build, a simple wooden DIY stool made from reclaimed wood.
See my recent Elevated Planter Box and my other contributor projects here.
You can't beat the character of reclaimed wood. I used this same wood for shelving in my Teen Boys Bedroom Reveal, it is just so pretty!
The idea for this DIY step stool came from these cute wood stools I spied in Target one day. I snapped a quick photo, because that is what I do when I want to build something.
It is a good thing I did, because I have not been able to find this stool online, anywhere…so I don't even know if they sell them anymore.
Never you fear! You can make your own following the plans I put together — you can use actual reclaimed wood or new wood, either will work!
How to Make a DIY Wood Stool
click here to see the photo tutorial at Mylove2create
This post contains affiliate links for your convenience. See our full disclosure policy here.
Wood Stool Dimensions
Following the woodworking plans and using 3/4″ thick boards, the farmhouse wood stool measures 17" W x 11" D x 14" H.
Note: If you use thicker reclaimed wood, the height will vary a bit due to the added thickness of the top — Mindi's stool is closer to 14 1/2″.
If you need a taller step stool, build a flip-over barstool step ladder (24″ tall) or a DIY ladder chair (~46″).
DIY Wood Stool Materials
- printable woodworking plans
- (1) – 1" x 10" x 6' board (actual ¾" x 9 ¼")
- (1) – 1" x 6" x 6' board (actual ¾" x 5 ½")
- (1) – 1" x 2" x 8' boards (actual ¾" x 1 ½")
- (~21) – 1 ¼" pocket hole screws
- (~2-4) – 2" wood screws or 2″ brad nails
The longest length of wood needed for this DIY wooden stool plan is ~17″, so this is a great scrap wood project, too!
I used different widths of boards that I pieced together to get the widths I wanted for the top and legs, but the material list includes the widest readily available boards to make it easy if you're buying new wood.
Using reclaimed wood makes this DIY stool so beautiful with the automatic character of the old wood!
You can use new wood, too, of course, and give it a reclaimed look by beating it up a bit like I did on my console table or by using a rustic layered stain technique like I did on the super easy farmhouse wood bench.
*Please note I am giving the dimensions for 3/4" thick wood in the supply list and in the woodworking plan cut list. The wood I actually used is 1" thick reclaimed wood, and it can be more difficult to find, but the cut list can be used for either thickness, or you use a thicker wood too, modify to fit your needs/wants, the true beauty of DIY. 🙂
Tools needed
- Miter saw
- Kreg Pocket hole jig**
- Nail gun and nails
- Drill
- Clamps
- Sander
- Finishing supplies as desired
Tips for ripping boards using a circular saw
Using reclaimed wood meant I was working with boards of different widths than you can buy at the store, so I pieced boards together to fit the cut list dimensions from the plans.
To make the legs wider, like my inspiration piece, I needed to rip one of the three leg boards in half for an extension to be added to the two leg boards.
Rather than getting out the table saw, I grabbed my trusty tool combo, my Ryobi Circular saw and my Kreg Rip Cut to do the job.
If you are using 1×10 boards you don't need to do this step the wood is the perfect width for the legs.
In the top left photo you can see how I have clamped my wood, this will enable me to use my rip cut around the clamp (see top right photo).
I set my rip cut so that the board will be cut right in half, and the 2×4 support board is over enough so that my blade will not hit it while I rip the board.
Tips for ripping boards using a jigsaw
When I did a dry fit on the wooden stool pieces, I realized I didn't like how wide the apron pieces were and I wanted them much smaller (which is why I listed 1×2 boards in the plans instead of thicker).
Without my table saw set up, I knew it would be dangerous to rip a narrow piece like this on a miter saw, and impossible with my rip cut, so I busted out my jig saw!
I used a scrap piece of 1×2 as my thickness guide, and marked it on my apron (top left). Then I clamped my piece on one end and cut as far as I could with my jig saw.
I unclamped it and flipped it around and cut the rest of the line. I followed the same process with both apron pieces to get the width I wanted. Done, and so easy! And safe. 😉
Tips for Pocket Holes on 1″ Thick Lumber
My reclaimed wood was 1" thick and so I need to adjust my Kreg Jig and depth collar on my drill bit accordingly.
If you are using 3/4" thick wood you will need to set the adjustments for that thickness.
You can see how easy it is to drill pocket holes with an angled cut, just make sure the cut end is flush to the bottom of the jig when you clamp it in.
Here is a shot of all my pocket holes. The ones on the top of the legs will screw into the top seat board. (And all of these pocket hole locations are detailed in the woodworking plans!)
I also want to point out that I had to adjust my screw length to 1 1/2" in order to match my board thickness. This it very important to remember when using a pocket hole jig.
Again, if you are using 3/4" wood you will use 1 1/4" pocket hole screws.
Building a Simple DIY Wooden Stool
Get the full cut list and dimensions in the printable wooden stool plans. The plans include the full assembly instructions as well, which are also detailed in the photos here.
Step 1: Assemble Wood Stool Seat
After you've cut the pieces to length with the dimensions and bevels listed in the plans, you'll attach the 2 seat pieces together using wood glue and pocket holes screws.
I always make sure to clamp my boards in this process so my boards don't shift while drilling in the screws.
Step 2: Assemble the Stool Legs
To build the stool, I started by adding the two apron pieces to the top of one leg, making sure they were flush with the top (top photos).
Then I glued and clamped the other leg to the apron pieces and added my screws.
I did need to use a shorter drill bit for this, because the space was tight. Using Right Angle Drill or Drill Attachment is really helpful.
I want to note that you can build the stool legs without pocket holes as well, just pre-drill and screw through the legs from the outside into the apron pieces using 2 to 2 1/2" screws.
I measured and marked where I wanted my support board on the stool legs and attached it with my pocket hole screws.
Step 3: Attach Leg Assembly to Seat
On the bottom side of the stool seat I measured and marked where the top of the legs needed to be placed. I love using a combination square for quick accurate marking.
That's it! Just 3 steps to build your own DIY wood stool!
Click here to add the wooden stool DIY plans to your cart.
Finishing the DIY Reclaimed Wood Stool
Since I had exposed fresh edges with my cuts, I needed to stain them to match the natural reclaimed wood look.
I decided to go with a natural vinegar and steel wood stain (like this recipe) to help unify the pieces with a nice natural grayish color.
On the left I tested it on a scrap piece to see if I liked it, on the right I am applying it to the stool.
I have used this same stain on several projects like my Chalkboard Coat Rack and my Marvel Subway Art.
You may have noticed that I filled in my pocket holes with wood filler…I wasn't entirely sure I should have done that, I think they might have blended better without being filled.
Oh well, life lessons, I did try and paint them with some craft paint to try and blend them better, but totally forgot to take photos of that process…but I don't think I did a very good job anyway. Ugh. Thankfully they're not that visible now at least.
I sealed it with three coats of poly, sanding with 400 grit sandpaper between coats one and two for a nice smooth finish.
This shot is by my front door right under the mailbox, and it might be a good home so my kids aren't moving the porch chairs to get the mail every afternoon!
It looks great in my boys room, but I might steal it for the kitchen! 🙂 It's a good thing I am not indecisive! (wink wink)
Click here to get the simple wooden stool plans.
This really is a simple build especially if you use the dimensional lumber I provided in my cut list.
You can always get creative with your finish and make it look like reclaimed wood (using a method like this or this or this homemade stain), or just paint it!
More great projects for reclaimed wood:
- DIY antique wood cutting boards
- reclaimed wood herringbone coffee table
- easy rustic photo frames
- reclaimed wood "home" latitude and longitude sign
- floating reclaimed wood vanity
- reclaimed wood planked kitchen island or backsplash


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Layer 7 Innovations is a Toronto, Canada based Virtual, Augmented and Mixed Reality Solutions Company that is focused on creating out-of-the-box platform solutions for SMEs and enterprises across global markets. With the 4th industrial revolution gathering full steam we see organizations turning toward new technologies to get ahead and beat the competition. We are certain that virtual & augmented reality has the potential to penetrate almost every area of our lives soon.
Layer 7 Innovations' culture is based on a people driven Company approach that places people front and centre of all we do as a company.


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Engage With Your Base With Online Gaming: Create Strong Brand Ambassadors For Your Business
Special to Hudson Valley Public Relations by Frank Morello, Intern Marist College
Over the past decade, gaming has grown to exponential heights, going from a niche market to a household activity, something that both children and adults alike take part in. This is partly due to things like the recent success of Nintendo's Wii system, as well as gaming's foray into the smartphone world through apps.
Gaming is now something that mostly everyone partakes in daily, whether it's sitting down on your couch and playing Call of Duty with some friends, or opening up Candy Crush on your iPhone and tapping away for 15 minutes during your morning commute.
Marketers have been quick to see the very apparent opportunities in using gaming as a marketing tool. With its nearly universal appeal gaming is something that can be used to reach all kinds of people, all across the globe.
Mobile gaming is by far the most popular form of gaming, with millions of apps offering fun, bite sized gaming fun to the millions of smartphone owners all across the globe. Mobile games are generally cheap to make, free to distribute and have shown their ability to promote products and services effectively time and time again.
Advertising-based video games, also referred to as "advergames" in the industry, have been used by companies to market their brands since as long as video games have existed. Advergames started out far before the Internet, and were normally distributed for free on floppy disks or CDs.
The Main Goals Of Advergames Are One of Two Objectives:
- To Promote Incentives that Drive Responses.
- And to Deliver Awareness to the Customer.
Historically, advergames were normally distributed from the company direct via the mail. Typically the customer mails in UPC codes from the product being advertised.
This creates a response function:
- Gives the consumer an incentive to both purchase the product.
- And take the necessary steps to obtain the game.
As a result of this response function, customers would then receive a game whose primary goal is to:
- Promote and remind the core consumer of the product.
- Create brand identity and loyalty about the product while providing free entertainment.
Incentives work best with loyal consumers who identify with the brand and are repeat customers. The main goal of gaming is to create a brand experience that associates the game with the brand to build brand loyalty and to stimulate repeat product purchase.
Some of the earliest examples of advergames can be seen in a partnership between Mattel's M Network division and Kraft Foods. Mattel and Kraft joined forces to create the "Kool-Aid Man" video game for the Atari 2600 system in 1983.
Intended to promote Kool-Aid, buyers of the product could mail in UPC symbols from Kool-Aid containers in order to receive the free game. It was later available for retail purchase. Kraft made use of the crossover in audience between people who drank Kool-Aid and those who video game players. All the while building brand identity, loyalty to stimulate product purchase. The game fundamentally functioned as an interactive advertisement. Players become involved with controlling the Kool-Aid mascot through various levels of the game.
Coca-Cola has done an excellent job creating branded games, like they did with their My Beatmaker app for the Olympic games. Coca-Cola's mobile game "Crabs and Penguins" was designed with the idea to keep customers engaged for a long time. This mobile app allows players to unlock levels and become engrossed in a story, all with Coca-Cola branding throughout. Users are constantly reminded of the Coca-Cola brand while playing the game, truly combining awareness with engagement.
These games all reinforce the brand while creating an engaging, emotional connection with their target audience. Many other companies have joined Coke in creating branded gaming content for the mobile market, reaching their target market directly through something they love.
Finding a free advergame in a cereal box was commonplace in the 90's. The core target base enjoyed the cereal while having fun playing the branded game. "Chex Quest" was a wildly popular CD-ROM game in 1996, that was included in the purchase of a box of Chex Cereal. The "Chex Quest" game was very similar to the game "Doom" which was a bid success for both fans and critics alike.
More Examples of Effective Video Game Market Promotions
Burger King started selling three different "King Games" at their restaurants for an additional $3.99 for the Xbox and Xbox 360 systems. The games were a massive hit, selling over 3.2 millions copies in the US and Canada alone. "King Games" was the highest selling game of the 2006 holiday season.
Doritos released multiple free Doritos based games through the Xbox Live service to promote their product. The game was downloaded 1.4 millions times in it's first month of release.
Kim Kardashian teamed up with mobile app developer Glu Mobile to create the mobile game "Kim Kardashian: Hollywood" for iPhone and Android. The game successfully created high levels of awareness Kardashian's television show and generated over $1.6 million in it's first five days of release through micro-transactions.
Advertising-based video gaming is a massive industry in itself. Profits from gaming exceeded over $207 million in 2007, and expected growth is projected to be explosive. Mobile gaming is now tactically used to promote many brands. Most of the games are free and can be played on smartphones by downloading the apps from the Apple App Store or Google Play Store.
As the popularity of advergames grows, so will the ways to create brand loyalty and product usage.
To learn more about gaming or creative ways to grow your business, give us a call at 845.202.7087 or visit our website at www.hudsonvalleypublicrelations.com.
Kuo A, Rice D. Catch and Shoot: The Influence of Advergame Mechanics on Preference Formation. Psychology & Marketing [serial online]. February 2015;32(2):162-172. Available from: Business Source Premier, Ipswich, MA. Accessed March 27, 2015.
Campenelli, Melissa. "eMarketer: In-Game Advertising Spending To Reach $650 million in 2012". Online Marketing Strategies and Tactics. Retrieved from http://www.emarketingandcommerce. com/article/emarketer-game-advertising-spending-reach-650-million-2012/1
Burke, Adrienne. "Even Small Brands Can Use Game Apps To Engage Customers". Yahoo Small Business Investor. Retrieved from https://smallbusiness.yahoo. com/advisor/blogs/profit-minded/even-small-brands-game-apps-engage-customers-215648712.html
Goh, Khim-Yong, and Jerry Wenjie Ping. "Engaging Consumers with Advergames: An Experimental Evaluation of Interactivity, Fit and Expectancy." Journal of the Association for Information Systems 15.7 (2014): 388-421. ProQuest. Web. 1 Apr. 2015.
Photo source: http://www.cheatcc. com/imagesfeatures/advergames.jpg


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Jonah 1:11-16
11 So they said to him, "What should we do to you that the sea may become calm for us?"-for the sea was becoming increasingly stormy. 12 He said to them, "Pick me up and throw me into the sea. Then the sea will become calm for you, for I know that on account of me this great storm has come upon you." 13 However, the men rowed desperately to return to land but they could not, for the sea was becoming even stormier against them. 14 Then they called on the LORD and said, "We earnestly pray, O LORD, do not let us perish on account of this man's life and do not put innocent blood on us; for You, O LORD, have done as You have pleased." 15 So they picked up Jonah, threw him into the sea, and the sea stopped its raging. 16 Then the men feared the LORD greatly, and they offered a sacrifice to the LORD and made vows.
There is a verse in Romans 8 that many people remember for times of trouble:
26 In the same way the Spirit also helps our weakness; for we do not know how to pray as we should, but the Spirit Himself intercedes for us with groanings too deep for words; 27 and He who searches the hearts knows what the mind of the Spirit is, because He intercedes for the saints according to the will of God. 28 And we know that God causes all things to work together for good to those who love God, to those who are called according to His purpose.
Generally, we only refer to verse 28, but as we can see, the Holy Spirit works in and upon us in accordance with His good will. It is at this point we recognize that God used Jonah's disobedience to reveal His sovereignty. Did He call upon Jonah to go to Nineveh knowing he would flee and take this boat? If we recognize God's complete control over everything then the answer is not only yes, but we can take it one step further to say that God called Jonah to go not just for the salvation of Nineveh, but also the men on this boat! Too often we diminish God's sovereignty and how He orchestrates things in and through us. We limit His sovereignty in our minds to only what we could possibly orchestrate in our own lives.
At this point, Jonah finally took responsibility for his own actions and disobedience. We can liken it to when an entire class of students gets punished for something one student did and the teacher is trying to draw out the guilty party. We are ok with taking our own punishment because we recognize that we deserve it, but when others are affected, our guilt weighs on us too much and we generally fess up to our wrongs so that others don't have to suffer for our disobedience. Some of you might be wondering, "but why did God put the lives of others at risk just to make a point?" Again, He was completely in control the whole time. The crew might have thought they were going to die, but they weren't and they didn't. As Jonah took responsibility for his actions, God was glorified.
We saw earlier that each man prayed to his own god, looking for mercy from whoever was willing to give it. They recognized, once the storm calmed, the great power of the Lord Almighty. They recognized His sovereignty and genuinely feared Him. It was Jonah's sacrifice to jump off the boat that led to the salvation of these men. So what then, does that mean for us? We will see soon what happens once Jonah puts aside his own feelings for Nineveh and sacrifices his own desire for that of God's. Sometimes God has to take us to a place where we recognize that self sacrifice is the only way we can comply with God's will. This is why Jesus said in Matthew 16:
24 Then Jesus said to His disciples, "If anyone wishes to come after Me, he must deny himself, and take up his cross and follow Me. 25 "For whoever wishes to save his life will lose it; but whoever loses his life for My sake will find it.
Our cross isn't a burden we must bear every day, it is the device by which we die to ourselves so we can live freely within God's will! We constantly reference this verse and mourn our cross as a daily burden when we should be celebrating the freedom and calmness it brings in our life! Jonah's cross was to be obedient and go to Nineveh, forsaking his own will and complying with God's. How is God calling you to deny yourself today and follow Him?


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The destructive environmental and socio-economic impacts of the El Niño/Southern Oscillation (ENSO) demand an improved understanding of how ENSO will change under future greenhouse warming. Robust projected changes in certain aspects of ENSO have been recently established. However, there is as yet no consensus on the change in the magnitude of the associated sea surface temperature (SST) variability, commonly used to represent ENSO amplitude, despite its strong effects on marine ecosystems and rainfall worldwide. Here we show that the response of ENSO SST amplitude is time-varying, with an increasing trend in ENSO amplitude before 2040, followed by a decreasing trend thereafter. We attribute the previous lack of consensus to an expectation that the trend in ENSO amplitude over the entire twenty-first century is unidirectional, and to unrealistic model dynamics of tropical Pacific SST variability. We examine these complex processes across 22 models in the Coupled Model Intercomparison Project phase 5 (CMIP5) database, forced under historical and greenhouse warming conditions. The nine most realistic models identified show a strong consensus on the time-varying response and reveal that the non-unidirectional behaviour is linked to a longitudinal difference in the surface warming rate across the Indo-Pacific basin. Our results carry important implications for climate projections and climate adaptation pathways.
Original language | English |
Pages (from-to) | 786-790 |
Number of pages | 5 |
Journal | Nature Climate Change |
Volume | 4 |
Issue number | 9 |
DOIs | |
Publication status | Published - 2014 Sept 11 |
Bibliographical note
Funding Information:We acknowledge the World Climate Research Programme's Working Group on Coupled Modelling, which is responsible for CMIP, and we thank the climate modelling groups for producing and making available their model output. For CMIP the US Department of Energy's Program for Climate Model Diagnosis and Intercomparison provides coordinating support and led development of software infrastructure in partnership with the Global Organization for Earth System Science Portals. S.T.K. is supported by CSIRO Office of Chief Executive and Wealth from Oceans Flagship, and W.C. is supported by the Australian Climate Change Science Program, and a CSIRO Office of Chief Executive Science Leader award. A.S. is supported by the Australian Research Council. S-I.A. is supported by the National Research Foundation of Korea Grant funded by the Korean Government (NRF-2009-C1AAA001-2009-0093042).
All Science Journal Classification (ASJC) codes
- Environmental Science (miscellaneous)
- Social Sciences (miscellaneous)


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VSAC will transfer the servicing of your Federal Student loans to American Education Services and the guarantee of all VSAC Federal Student loans to the Trellis Company, an approved Federal Guaranty Agency, over the weekend of March 16th. Click here for more information.
VSAC Announces Improvements to College Savings Program
The Vermont Student Assistance Corporation (VSAC) has renewed its agreement with TIAA-CREF Tuition Financing, Inc. (TFI) to manage the Vermont Higher Education Investment Plan (VHEIP) — Vermont's official 529 college savings plan — and is offering several enhancements to benefit Vermont families.
The number of VHEIP investment options has expanded from three to six to provide families a wider range of choices with varying strategies and degrees of risk. Investors may choose options that range from conservative to aggressive, selecting those that best fit their college savings objectives and investment philosophy.
In addition, program management fees have been restructured to help account owners put more of their investments toward their college savings goals. Of particular note, fees have been reduced for the Managed Allocation Option, a popular choice for many families because the underlying investments automatically adjust as the student beneficiary ages.
As of September 30, the investment lineup is as follows:
Managed Allocation Option — fees decrease from 80 to 53 basis points (50 basis points equals one-half of a percent)
Interest Income Option — continues as a zero-fee option
100% Equity Option — fees remain at 80 basis points
Equity Index Option (new) — fees set at 53 basis points
Balanced Option (new) — fees set at 70 basis points
Fixed Income Option (new) — fees set at 78 basis points
Effective November 30, two options will change:
The Interest Income Option will be renamed the Principal Plus Interest Option with a guaranteed principal investment strategy — continues as a zero-fee option
The 100% Equity Option will be renamed the Diversified Equity Option with an active management strategy — fees increase to 89 basis points
In addition to those changes, plans are underway to make managing a VHEIP account online much easier. Account owners will be able to view electronic quarterly and annual statements online, rebalance existing assets to new or existing investment options, and make withdrawals to the bank account on record.
Vermont Higher Education
The Vermont Higher Education Investment Plan launched in December 1999 and has grown to an asset value of $100 million in about 9,600 accounts. VHEIP is the only 529 plan for which Vermont taxpayers can claim a state income tax credit of up to $250 per taxpayer per beneficiary (up to $500 for married couples filing jointly) on contributions in each taxable year. Also, contributions and any earnings grow free from federal and Vermont income taxes; withdrawals remain tax-free as long as they are used for qualified expenses, including tuition, room and board, books, and fees at most colleges nationwide and some abroad.
A VHEIP account can be opened for as little as $25 per investment option, and individuals can make periodic or regular contributions to the account with a minimum of $25 (or $15 per pay period by payroll deduction, if offered).
The program Web site — www.vheip.org — provides complete information and online enrollment. Information and applications can also be obtained by calling toll-free 1-800-637-5860. There are no income or residency restrictions on who can open an account.
VSAC is a public, nonprofit corporation established by the Legislature in 1965 to help Vermonters plan and pay for education or training beyond high school. TFI, a national leader in managing 529 college savings plans, is part of the TIAA-CREF group of financial services companies, the leading provider of retirement services in the academic, research, medical, and cultural fields.
This entry was posted on Thursday, October 8th, 2009 at 12:03 pm and is filed under News & Views, VSAC News Releases. Both comments and pings are currently closed.


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Gust showed off the latest gameplay footage of Atelier Lydie & Suelle: Alchemists of the Mysterious Painting during a recent live stream, where we got to check out Firis and her sister Liane, as well as the recently revealed Plachta and other characters.
In addition to a look at Lydie and Suelle interacting with some new and familiar faces, the gameplay footage shows us some of its synthesizing system, exploration of a mysterious painting world, and some battle action.
Check out our previous report for info on two recently revealed alchemists Lucia and Alto, as well as some more information on the synthesis system and worlds you'll get to explore.
Atelier Lydie & Suelle: Alchemists of the Mysterious Painting releases in Japan on December 21, 2017 for PlayStation 4, PlayStation Vita, and Nintendo Switch.