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Polyarteritis nodosa is a serious blood vessel disease in which small and medium-sized arteries become swollen and damaged.
Periarteritis nodosa
Polyarteritis nodosa is a disease that affects arteries, the blood vessels that carry oxygen-rich blood to organs and tissues. The cause is unknown, but it occurs when certain immune cells attack the affected arteries.
More adults than children get this disease. The tissues that are fed by the affected arteries do not get the oxygen and nourishment they need, and become damaged.
People with active hepatitis B and C may develop this disease.
Symptoms are caused by damage to affected organs, often the skin, heart, kidneys, and nervous system.
Symptoms include:
If nerves are affected, you may have numbness, pain, burning, and weakness. Damage to the nervous system may cause strokes or seizures.
No lab tests are available to diagnose polyarteritis nodosa. You will have a physical examination.
Lab tests that can help confirm the diagnosis include:
Treatment uses medications to suppress the immune system, including steroids such as prednisone. Often, similar medications, such as cyclophosphamide, are used.
For polyarteritis nodosa that is related to hepatitis, treatment may involve plasmapheresis and antiviral medicines.
Current treatments with steroids and other drugs that suppress the immune system (such as cyclophosphamide) can improve symptoms and the chance of long-term survival.
The most serious complications usually involve the kidneys and gastrointestinal tract.
Without treatment, the outlook is poor.
Call your health care provider if you develop symptoms of this disorder. Early diagnosis and treatment may improve the chance of a good outcome.
There is no known prevention. However, early treatment can prevent some damage and symptoms.
Sergent JS. Polyarteritis and related disorders. In: Harris ED Jr., Budd RC, Genovese MC, Firestein GS, Sargent JS, eds. Kelley's Textbook of Rheumatology. 8th ed. Philadelphia, Pa: Saunders Elsevier; 2008: chap 83.
Stone JH. The systemic vasculitides. In: Goldman L, Schafer AI, eds. Cecil Medicine. 24th ed. Philadelphia, Pa: Saunders Elsevier; 2011: chap 278.
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text: Hey, looking for some advice on setups for these two sticks. I'm sure I can dig up some stuff scattered on the site, but maybe people have some fresh perspectives. 1. On the Speed, I currently have a full bed of Babolat VS Natural Team Gut 17 at 58. I've only had this stick for a couple of weeks, so just learning its ins and outs. I'm generally happy with the VS, and will play with it until it wears, but curious about different set ups to unleash the Speed's full potential. I know Nole uses VS and ALU (at least, that's what public sources say), but I'd be willing to try a full bed of poly/co-poly, if people have found success. 2. On the Aero Pro Drive, I've really only used RPM blast in a full bed and hybrid set up. Really frustrated with this stick. Everything seems to sail after a few days of play and never get the desireable feel. I'm considering trying a full bed of some type of poly or co-poly (other than RPM). Perhaps Solinco Tour Bite 16L (1.25) or Yonex Poly Tour Spin 1.25 16L. Please let me know your thoughts and what's worked for you. Thanks for your time and advice.

subset: commoncrawl


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At paint night, participants 21 and over unleash their inner Picasso by painting their own replica of a certain subject. The instructor gives step-by-step instructions, but encourages guests to add their own flair.
A rise in "just add alcohol" events has been sweeping the nation, including luxury movie theaters, nail salons and boutiques. Shown by the popularity of "paint nights" at dozens of restaurants in the area, the South Shore prefers its cocktails mixed with creativity.
At paint night, participants 21 and over unleash their inner Picasso by painting their own replica of a certain subject. The instructor gives step-by-step instructions, but encourages guests to add their own flair. The $30 lesson covers paint, brushes, a canvas, easels and appetizers.
Turner's Yard, a popular gastro-pub in Pembroke, first hosted the social event in May. There was such high attendance that they didn't have enough easels. The restaurant booked Pour Artist owner and Instructor Heather Martin of Weymouth for the rest of the year.
"It's a creative alternative to just going out for a cocktail," Martin said. "When you're here you forget about work, bills and stress. You're only focused on having fun."
Fun, rather than precision, was definitely the theme of the paint night at Turner's Yard on Thursday, August 22, where 30 women showed up for the lesson. While Martin gave detailed instructions on how to paint a bouquet of flowers, students laughed over their mistakes, gave updates on their kids' whereabouts, raved over the food, and tagged themselves on Facebook.
"Most of these people work in white-walled offices where they can't be artistic," Sharon Browne, of Hull, who learned about the event through her friend, who sat beside her, Cathryn Liscombe of Pembroke. "It's a fun way to go out with friends while being creative."
Despite the carefree tone of the event, many participants showed up wary of their artistic abilities, claiming they could only produce stick figures. Liscombe said she was stressed as she first picked up her paintbrush, while Martin laughed and assured her that no experience is necessary.
"People come in here every time saying 'I can't do this'" Turner's Yard events manager, Jan Nguyen, of Pembroke said. "They're amazed when they leave with this beautiful painting."
Sheila Palumbo, of Hanson, used to be nervous when she first starting attending paint nights – but that was months ago. Now, she has become one of Martin's regulars. She recruited friends to join her, and even hired Martin for an upcoming event at her church.
"It's a great night full of food, friends and alcohol," Palumbo said, with her friend and fellow regular, Deb Johnson of Cedarville. "Then you get to walk away with this beautiful piece of art. We're huge fans."
If you can't make it to an event with the Pour Artist, check out the dates at Paint Nite and Sip, Dip, and Dabble, which also host local paint events.
Like Martin, June Alexandra of Sip, Dip, and Dabble also has impressive turnouts for her paint events. She said she believes it's so popular because anyone can do it.
"People are so amazed and proud of themselves when they see what they've accomplished at the end of two hours," she said. "So amazed, in fact, they come back and bring a friend."
Upcoming paint nights are: The Pour Artist at The Black Raspberry Pub in Plymouth, tonight; Paint Nite at Mr. Dooleys in Cohasset, Monday, Sept. 16; Paint Nite at Hingham Beer Works in Hingham, Monday, Sept. 16; Paint Nite at Cagney's Pub in Quincy, Tuesday, Sept. 17; Sip, Dip and Dabble at Ledge Kitchen & Drinks in Dorchester, Wednesday, Sept. 18; The Pour Artist at Turner's Yard in Pembroke, Thursday, Sept. 19; The Pour Artist at Turner's Yard in Pembroke, Thursday, Oct. 17.
Mary Pavlu may be reached at firstname.lastname@example.com.
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Market discount narrows
AN OPPORTUNITY appears to have arisen for investment companies to list on the sharemarket as the market discount of listed investment companies narrows.
Over the past year, listed investment companies have returned 22 per cent on average, which has prompted Naos Asset Management, with about $20 million under management in two unlisted funds, to test the waters in the listed space.
It is seeking to raise up to $50 million for its Naos Emerging Opportunities Co, which is to invest in emerging companies that are outside the S&P/ASX 100 Index, but not microcaps. ''We can be 100 per cent cash, or hold up to 15 to 20 positions,'' Naos managing director Sebastian Evans said. ''It will be a high-conviction fund.''
Chaired by former Macquarie banker David Rickards, with another ex-Macquarie banker, Warwick Evans, as a director, management and directors are putting $2 million of their own money into the fund.
''The rush for yield is on its way to reaching a climax,'' Mr Evans said, with the fund to focus on poorly understood or overlooked stocks.
The Naos prospectus follows Contango Asset Management seeking to raise $200 million for a listed fund.
Amid a rally of the listed investment company sector over the past year, Djerriwarrh and Mirabooka have been pushed to trade at a premium of 21 per cent and 13 per cent respectively, while the three listed funds in the Geoff Wilson stable - Wilson Asset Management, Wilson Active and Wilson Research - are trading at about net asset backing, as is Cadence Capital, Australian Leaders and Mercantile Investment.
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