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I knew this day was coming but its still hard now that its here. Microsoft is officially killing off windows live mesh and replacing it with Sky Drive. Sky Drive is great and all (maybe... I don't know or care actually) but along with this shift they are taking away the one feature of mesh that I loved which was the instantaneous direct syncing of files from one computer to another without using a specific folder or messing with symlinks.
I like to keep my documents, music and pictures synced between my desktop and laptop. I could theoretically prune it down but that would take a lot of work and I'd rather just have it all no matter what computer I'm using. In total its probably 100 GB and tens of thousands of files. For me it doubles as backup system. I don't need a way to access the files over the internet (Thats the beauty of having them locally!).
Does anyone know of any free alternatives out there? The closest thing I came across was http://www.cubby.com but to get the direct syncing between computers costs money. Other ideas? Anyone else disappointed that mesh is going the way of the dodo?


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Sandie Cohen started quilting 10 years ago on the recommendation of an artist friend, whom she had asked for painting lessons.
"I have virtually no drawing or painting skills," Cohen laughs. "But I've always been a very good sewer. My grandfather was a tailor. I made my children's clothes when they were young. It seemed like quilting might come natural to me."
She's now crafted over 50 quilts.
To read more on Cohen, pick up a copy of this week's Arts & Entertainment section in The Observer.

subset: commoncrawl


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- Japanese Grand Prix - FP2
Qualifying will be crucial - Vettel
- Race:
- Japanese Grand Prix
- Drivers:
- Sebastian Vettel
- Teams:
- Red Bull
Sebastian Vettel believes qualifying will be crucial for the Japanese Grand Prix and is predicting a "very, very tight" session on Saturday.
Having been 17th in the morning practice session, Vettel improved in the second session and was third quickest in FP2 at Suzuka. He admitted that he had not been comfortable with the way the car was handling in FP1 but said further progress was going to be required overnight after a close Friday between Red Bull and McLaren.
"I think overall we had a good day," Vettel said. "This morning the car was very nervous and I think we lost out a little bit compared to the others but this afternoon seemed to be quite a bit better, I was a lot happier and both compounds seem to perform reasonably well. Looking forward to tomorrow I think it will be extremely close so we need to make sure that we do another step overnight."
Despite his optimism, Vettel stressed just how important it would be for Red Bull to qualify strongly.
"We need to make sure we get our maximum. Days like today we were able to improve ourselves which is most important and we need to make sure - as I said - that we find something overnight because tomorrow I think will be a very, very tight qualifying session and I think for the race it will be very important where you will qualify."


text: AirAsia commences four inaugural flights from East Malaysia to Peninsular Malaysia KOTA BHARU, 22 March 2014 AirAsia continues to reinforce its connectivity between East and Peninsular Malaysia with the commencement of four inaugural flights from Sarawak to Penang, Langkawi, Terengganu and Kota Bharu. There are two new routes from Miri, and two more from Kuching connecting Sarawakians to the North and East Coast of Peninsular Malaysia. New routes from Kuching are to Kota Bharu (3x weekly), as well as to Langkawi (4x weekly). The Kuching to Kota Bharu inaugural flight took place today and AirAsia was honoured by the presence of Yang Mulia Dato' Seri Tengku Dr Zainal Adlin Bin Tengku Mahamood, Member of the Board of Directors of Tourism Malaysia, who was at the Sultan Ismail Petra airport in Kota Bharu to receive all guests on flight AK5507 from Kuching. The new Kuching – Kota Bharu route is AirAsia's ninth domestic route from Kuching, and the sole airline to connect Kuching directly to the East Coast of Peninsular Malaysia. AirAsia operates the Kuching – Kota Bharu route 3x weekly every Tuesday, Thursday and Saturday (refer flight schedule below for more details). The airline also commenced other new East Malaysia – Peninsular Malaysia flights yesterday, from Miri - Terengganu (3x weekly) and Miri – Penang (4x weekly), bringing the total to four new East Malaysia – Peninsular Malaysia connectivity. For more details, visit www.airasia.com. AirAsia connects both East Malaysia and Peninsular with 399x weekly flights, and offers the best connectivity within East Malaysia as well. Stay tuned to AirAsia's Twitter (www.twitter.com/AirAsia) and Facebook (www.facebook.com/AirAsia) for updates on latest promotions, activities and AirAsia news. Jadual penerbangan Kuching – Kota Bharu: Route Flight No Depart Arrive Frequency Kuching – Kota Bharu AK 5507 7.00am 8.55am Tues, Thurs , Sat Kota Bharu – Kuching AK 5508 9.20am 11.20am Tues, Thurs, Sat Flight Schedule for Kuching - Langkawi: Route Flight No Depart Arrive Frequency Kuching – Langkawi AK 5097 12.05pm 2.15pm Mon, Wed, Fri, Sun Langkawi – Kuching AK 5098 2.40pm 4.50pm Mon, Wed, Fri, Sun Flight Schedule for Miri – Penang: Route Flight No Depart Arrive Frequency Miri – Penang AK 5527 9.10am 11.35am Mon, Wed, Fri, Sun Penang – Miri AK 5528 12.00pm 2.25pm Mon, Wed, Fri, Sun Flight Schedule for Miri – Terengganu: Route Flight No Depart Arrive Frequency Miri – Terengganu AK 5513 9.10am 11.15am Tue, Thurs, Sat Terengganu – Miri AK 5514 11.40am 1.45pm Tue, Thurs, Sat


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In the paint, beyond the arc and mid-distance jumpers - points came frequent and diverse Monday, as the Arkansas Tech women defeated Cameron University 83-45 at Tucker Coliseum.
The output was 1-point shy of the Golden Suns' season high, dating back to an 84-64 win over Central Oklahoma on Nov. 18.
"We really executed well," said head coach Todd Schaefer. "I thought Cameron would give us problems with their athleticism, but we were able to take them out with our first shots."
Unlike Saturday's 53-48 loss to Northeastern (Okla.) State, the Golden Suns (4-4) were able to move the ball efficiently and add points to the scoreboard a number of ways.
Tech shot just 18 percent from the field in the second half of Saturday's game but shot nearly 60 percent and recorded more points in the first half Monday (52) than the entire game Saturday.
The Suns came out with a roar, making 11 of their first 12 field goals and taking the visitors out of the game early on. Tech built a 22-6 lead with just under 15 minutes to play in the first half.
The Golden Suns closed the half on a 19-7 run and led 52-19 at halftime.
The second half was a completely different story early on, as the Suns were held scoreless in the first five minutes of play, and the Lady Aggies (0-10) were able to cut the lead to 25. Schaefer made a five-player swap after he saw the third turnover in 5 minutes.
A new lineup improved the ball movement, and Tech was able to reclaim a dominant 30-point margin.
Following the official's timeout with 9:47 remaining, Schaefer made another five-player exchange, trying to find the energy the first-half Suns provided. Despite the coach's criticisms, the home side maintained a lead close to 30 throughout the rest of the game.
After hearing a mouthful from their coach, the Green and Gold players started doing the fundamental things that earned them the large lead and put the game beyond any doubt with a 40-point advantage.
Dardanelle native Katie McCormick ended the game with 13 points, while Lauren Dennis had 12 and Daiane Domingos had 11.
Schaefer praised freshman guard Amanda Grappe, who "didn't score a lot of points, but set the tempo."
"It all started with Ashley," he said.
Also on the coach's good side was freshman Julie Smith, who shot 3 of 4 from 3-point range.
The Suns' next game is scheduled for Wednesday at Southwestern Oklahoma. Tipoff is set for 6 p.m.
North Alabama 94, Tech men 91
The Wonder Boys dropped another close game Monday, falling 94-91 at North Alabama.
Details from the game were unavailable at press time and will be published in Wednesday's edition of The Courier.
Northeastern State 53, Tech women 48 (Saturday)
The Golden Suns came out flat against Northeastern State in a sloppy 53-48 loss Saturday at Tucker Coliseum.
Saturday marked the first action for the Tech women since their Dec. 6 victory over Central Missouri in a high-scoring 80-76 game, which had four Golden Suns scoring in double digits.
That winning formula was nowhere to be found Saturday. The Tech women held a 28-21 halftime lead but shot just 18 percent from the field in the second half.
"We didn't do a good job staying in our offense (Saturday)," Schaefer said. "(NSU) made us force everything, and we took shots that we didn't want to take."
NSU came out after halftime and quickly went to work on a 3-point shot from senior Wendy Fehrenbach. Following more Lady Red production, Tech found its lead slip to two early on.
Midway through the half, NSU's Adrienne Barnhill landed a 3-ball to give the visitors their first lead since the 11:13 mark in the first half.
Tech quickly countered after junior Krishna Baker scored on the ensuing possession, tying the game at 39 with 6:36 left on the clock.
With the game tied, Northeastern State was the first to take a stab at the lead on two consecutive baskets. The visitors managed to shut down the Suns' offense and stretched the lead to 53-46 with a minute to play in the game.
Junior Daiane Domingos came off the bench and was Tech's only double-digit scorer with 14. Baker, who played her first game of the season, came away with eight points and a team-high seven rebounds in 22 minutes of play.
Inconsistent shooting and poor shot selection was the theme early on, and the teams were tied 12-12 midway through the first half.
After the official's timeout with 9:33 remaining in the half, the Suns caught fire with an 11-0 run to earn a 23-12 advantage.
However, the Lady Reds were able to string together a run of their own late in the half and trimmed Tech's 11-point lead to five with under a minute left in the half.
A late basket by freshman Lauren Dennis gave the Suns a 28-21 halftime lead.


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Fish tapeworm
Fish tapeworm is an infection with a parasite found in fish.
Causes of Fish tapeworm
The fish tapeworm (Diphyllobothrium latum), is the largest parasite that infects humans. Humans become infected when they eat raw or undercooked freshwater fish that contain fish tapeworm cysts.
The infection is seen in many areas where humans eat uncooked or undercooked fish from rivers or lakes, including:
- African countries in which freshwater fish are eaten
- Eastern Europe
- North and South America
- Scandinavia
- Some Asian countries
After a person has eaten infected fish, the larva begin to grow in the intestine. Larvae are fully grown in 3 - 6 weeks. The adult worm, which is segmented, may reach a length of 30 feet. Eggs are formed in each segment of the worm and are passed in the stool. Sometimes, parts of the worm may also be passed in the stool.
Fish tapeworm infection may lead to vitamin B12 deficiency and anemia.
Fish tapeworm Symptoms
Most people who are infected have no symptoms. If symptoms do occur, they may include:
- Abdominal discomfort or pain
- Diarrhea
- Weakness
- Weight loss
Tests and Exams
People who are infected sometimes pass segments of worm in their stools. These segments can be seen in the stool.
Tests may include:
- Complete blood count, including differential
- Blood tests to determine the cause of anemia
- Vitamin B12 level
- Stool examination for eggs and parasites
Treatment of Fish tapeworm
You will receive medicines to fight the parasites. You take these medicines by mouth, usually in a single dose.
The drug of choice for tapeworm infections is praziquantal. Niclosamide can also be used. You may need vitamin B12 injections or supplements to treat the vitamin B12 deficiency and anemia that can occur with this infection.
Prognosis (Outlook)
Fish tapeworms can be removed with a single treatment dose. There are no lasting effects.
Potential Complications
- Megaloblastic anemia
- Intestinal blockage (rare)
When to Contact a Health Professional
Call your health care provider if:
- You have noticed a worm or segments of a worm in your stool
- Any family members have symptoms of anemia
Prevention of Fish tapeworm
Avoiding raw freshwater fish and cooking fish enough (to more than 140 degrees F for 5 minutes) will prevent infection with the fish tapeworm. Freezing fish to -4 degrees F for 24 hours also kills fish tapeworm eggs.
White Jr AC, Brunetti E. Cestodes. In: Goldman L, Ausiello D, eds. Goldman's Cecil Medicine. 24th ed. Philadelphia, PA: Saunders Elsevier; 2011:chap 362.
King CH, Fairley JK. Cestodes (tapeworm). In: Mandell GL, Bennett JE, Dolin R, eds. Principles and Practice of Infectious Diseases. 7th ed. Philadelphia, PA: Elsevier Churchill Livingstone; 2009:chap 290.
Related Images
|Review Date: 9/1/2013
Reviewed By: Jatin M. Vyas, MD, PhD, Assistant Professor in Medicine, Harvard Medical School; Assistant in Medicine, Division of Infectious Disease, Department of Medicine, Massachusetts General Hospital. Also reviewed by David Zieve, MD, MHA, Bethanne Black, and the A.D.A.M. Editorial team.


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So hypothetically speaking...If several hundred people were gullible enough to fall for this bologna, then wouldn't the "50,000" authors be getting hundreds of emails? If it was sent to each "author" twice and their "media contacts," then that means peoples inboxes would be flooded with hundreds of e-mails. Since that is obviously not going to happen....I doubt their newest scam will even work!
*** added a moment later ***
What I am was getting at, is if nobody on this thread receives an e-mail and nobody on the PA boards gets an e-mail...then what secret 50,000 authors are getting the emails? This idea is so dumb I have a hard time seeing how anybody would fall for it. Miranda didn't think this through. She should have sat on the can longer. Which is where she where she probably dreamed it up; considering how shitty it is, haha


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STARKVILLE, Miss. (WCBI/MSU Athletics) – Old Waverly Golf Club, one of the South's premier golf destinations located in nearby West Point, Miss., will become the new home to Mississippi State men's and women's varsity golf programs, the MSU Athletic Department announced Wednesday.
The Bulldog Club, the private fundraising arm of the Mississippi State Athletics, has partnered with Old Waverly on the $2.2 million project that includes a driving range, short-game area, putting green, plus a team clubhouse and indoor hitting bays. Over $1.3 million has been raised thus far.
The first phase, which features the team practice areas (driving range, a short-game area, and a unique putting green shaped as the state of Mississippi), is currently under construction and should be completed this fall.
A 6,300-square foot team clubhouse with locker rooms, players' lounge, coaches' offices, indoor putting center (with Sam PuttLab training system), exercise room and conference room will be constructed once fundraising is complete. The project will also feature a 2,431-square foot indoor hitting bay, equipped with two Trackman swing and ball flight analysis systems and a club repair room.
World-renowned golf course architecture firm Hanse Golf Course Design is planning the practice area and driving range. The company's founder, Gil Hanse, was elected "Architect of the Year" by Golf Magazine in 2009. Hanse Golf Course Design was recently selected by the Rio de Janeiro Olympic committee to design the host course for the 2016 Olympic Games.
Old Waverly was founded by MSU alum George Bryan. Mississippi State's Athletic Administration building, the Bryan Building, if named after his father, John H. Bryan Sr.
"The proximity to Old Waverly, along with the long history between the Bryan family and Mississippi State, made this project possible," said MSU Athletics Director Scott Stricklin. "The new Bulldog golf facility will be one of the finest of its kind in the nation. The all-encompassing facility will dynamically enhance our golf programs and provide our student-athletes with all of the tools necessary to develop their skills on the course."
A fixture on the annual Golfweek Top 100 and Golf Digest 100 "Greatest Courses in America," Old Waverly is one of the South's classic par-72 layouts. Since 1990, Old Waverly has hosted numerous events, including the men's and women's Southeastern Conference Championship, Southern Golf Association Women's and Junior Championships, the 2006 U.S. Women's Mid-Amateur Championship, as well as the 1999 U.S. Women's Open.
"This opportunity that Old Waverly Golf Club and our donor family is providing is program changing," said MSU women's head coach Ginger Brown-Lemm. "Our program has grown tremendously, and I look forward to seeing what the future holds with a facility of this caliber. The future of Mississippi State golf is exploding with excitement and promise."
"With the support of the Bryan family and other key donors, we will soon have one of the top facilities anywhere," said MSU men's head coach Clay Homan. "This facility has been given a tremendous amount of thought and planning and is sure to give our student-athletes all they need to excel at the highest level."
In 2013-14, the MSU women's team posted its all-time best NCAA Championship finish, taking sixth place, while the Bulldog men reached NCAA Regional play for the second straight year.


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I'd love to get this system . . . but only if it had the iPod dock!
Sonoro Cubo Compact System
Sonoro is a German audio manufacturer. The company recently commissioned a survey on the listening habits of 560 consumers. Thirty-nine percent of them named FM radio as their number one audio entertainment source, beating iPods and other MP3 players at 23 percent. That was interesting, but when I visited the Sonoro site, I found something even more interesting: the Cubo system.
It's bigger than it looks, at five inches high, 8 wide, and 9.5 deep. Available colors include numerous sedate earthtones, plus red, pink, and the sweet lime green I chose for the review sample. It comes packaged with a pair of white linen gloves to prevent your fingers from marring the glossy surface of the unit or its dock. The front panel includes a large backlit amber liquid crystal display, with tuning buttons to the left and volume buttons to the right. Below the slot-loading CD mechanism are transport keys. On the top is a single full-range speaker surrounded by station presets and other radio-related controls.
The Cubo comes with the best iPod dock every invented--or at least, the one I like the best. It consists of two pieces of transparent plastic that fit together to form a cradle. There's no iPod docking connector, perhaps making this a kind of non-dock. Instead, a mini-plug cable fits underneath into the iPod's headphone jack. True, a line-level connection through the docking connector would be audibly superior to going through the iPod's flea amp. And the Sonoro docking method won't charge the battery or perform other functions enabled by the docking connector. Why, then, do I prefer it?
Because I don't like charging the battery every time I connect one of my iPods to a system. I prefer to run the battery down to at least 25 percent before recharging. Even a lithium ion battery may lose some of its running time if charged constantly after brief uses--this is why Lenovo laptops include software that intelligently charges the battery as needed. If anyone would like to dissent, please do so in the comments field.
Sound is full and rich. With talk radio, there is definitely a bit of tubbiness with both male and female voices. The Cubo is more for music, which it enriches with a meaty rhythm section sound and a slick upper-midrange rolloff that takes the sting out of heavily equalized pop music.
Price: $350 via Saks Fifth Avenue.
Mark Fleischmann is the author of the annually updated book Practical Home Theater and tastemaster of Happy Pig's Hot 100 New York Restaurants.
The cubo is indeed a beautiful machine. Imagine my profound disappointment when my cubo (only 5 months old) was suddenly unable to recognise any CDs. The shop has taken it back in for repair - which means no music system until the New Year. On the whole a very frustrating experience - especially considering the purchase price of almost 300 euros. I suspend judgement.jpfholo257u8
The Sonoro Cubo is a compact, all-in-one sound system, complete with FM radio, CD player and auxiliary input for your portable media player. Each one is encased in a wooden enclosure with either a colored lacquer or natural wood finish. They come in a variety of colors, and make a dramatic statement on any bookshelf
finally i've found your review and comments which confirm my suspicion that i would not be the first purchaser of sonoro cubo to find that it doesn't recognise cds, nor probably the last. mine never has, since purchase last thursday. very disappointing. is there a solution before returning it to shop, as this is not easily accessible?
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text:
Multiplex Detection of Cell Surface Markers using Plasmonic Sensors
Published on
Gold nanorod molecular probes (GNrMPs) were designed and fabricated for multiplex identification of cell surface markers in HBECs. Cells were probed directly using dark field microscopy integrated with a spectral imager for simultaneous detection of up to three surface markers. The immunophenotype composition of these cell lines indicative of their metastasis potential was assessed using the GNrMPs. Due to the high multiplexing capacity of gold nanorods, the multiplexing capability of the GNrMP assay could possibly be expanded to 15 or greater. The technique has the potential to become an important tool for diagnosis and prognosis of breast and other cancers.
Breast cancer has the highest incidence among women in the western world affecting up to 10% of women and therefore is among today's most pressing health concerns.1 Despite improvements in diagnosis and treatment, the effect on mortality has been modest. Recent studies of breast cancer have identified a subpopulation (CD44+/CD24-) of breast cancer cells that demonstrated CSC properties.2 A direct relationship between progenitor states and invasive capacity of cancer cells (invasion being the first step in the metastasis cascade) was also established via flow cytometry analysis of various breast cancer cell lines for CD44 and CD24 phenotype and subsequent analysis of CD44+/CD24- (progenitors) and CD44-/CD24+ (non-progenitors) cells for invasion and metastasis using matrigel and xenograft models. It has been reported that five among 13 breast cancer cell lines (MDA-MB-231, MDA-MB-436, Hs578T, SUM1315, and HBL-100) contained a higher percentage (> 30%) of CD44+/CD24- cells.3 Hence, identification of cells of CD44+/CD24- immunophenotype within a population of tumor cells may have great value in terms of predicting the invasiveness and metastasis potential of the tumor. We report a procedure to fabricate gold nanorod molecular probes (GNrMP) and deploy these structures for multiplex detection(4-7) 10064.
Their team has developed a range of spectroscopic and biosensor technologies for disease diagnostics and food security monitoring. Tracking protein interactions and monitoring and detecting the dynamic state of single molecule events in cells is addressed through techniques such as Fluorescence Correlation Spectroscopy, FRET, Fluorescence lifetime imaging, enhanced single cell Raman spectroscopy , Plasmonic sensing, and Optical Trap.
He has published over 130 refereed research articles in areas covering thermodynamics and viscoelactic modeling of biological systems, spectroscopic methods, bio and nanomaterial sensors, and is a member of American Chemical Society, Institute of Biological Engineering, Biophysical Society, and American Association for Clinical Chemistry.
Cite this work
Researchers should cite this work as follows:
Centre for Cellular and Molecular Biology, Hyderabad, India