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Shipit — is a community of senders and travelers united by the mobile app that helps the former ship packages and the latter make extra money while traveling.
Shipit is a symbiosis of best ideas and practices of courier, crowdsource and crowdshipping services. We have synthesized the best business practices to create a revolutionary and unique service. Just as Uber and BlaBlaCar have already become a part of our daily lives, Shipit is going to become an irreplaceable tool for shipping.
It is the first app of its kind that will use smart contracts and blockchain as a native tool to make people lives easier all around the world. By implementing Shipit tokens and using the blockchain we want to build relationships between users based on transparency, safety and ease of tracking for all deliveries on the platform.
While courier services are becoming more expensive, Shipit allows users to ship and track open packages at lower costs and risks. Shipping has never been easier.
Shipit — Send packages. No couriers. Just people.
Millions of people ship packages daily and all around the world. However, there is a high chance of a sender running into issues of expensive shipping services, delivery delays, and high risks of shipments getting lost or damaged. Customs and postal services may cause a wide variety of troubles ranging from excessive paperwork to outright theft. At the same time those services cannot boast of outstanding efficiency and fast work: sometimes the shipments are delivered behind all reasonable deadlines. Aside from that, governments often charge different shipping fees and taxes inexplicable to the sender.
Commercial courier companies are not perfect as well. It is worth mentioning that courier and parcel delivery services have to employ a lot of people, machinery, and equipment units as well as to take care of insurance policies for their activities. All that leads to more than significant costs that are eventually carried by customers.
Delivery and courier services often cannot ship a parcel directly from point A to point B and are forced to resort to transit hubs which introduce even more threats and risks. Naturally, the increase in number of intermediary delivery and courier companies involved does not lead to increase of the responsibility of each party involved.
Although courier and parcel delivery companies have made our lives easier, they still have not fully addressed any of the questions above. Naturally, in the world of globalization and digitization and given the constant growth of global GDP and retail e-commerce sales, the significance of these issues is going to increase proportionally to the shipping volumes worldwide.
The world around us is rapidly developing and people all around the globe wanting to make things better than they are today may have only one viable option - to shift from the consumption and possession economy to the sharing economy.
Market growth
In spite of current difficulties, the global market of courier and parcel delivery services constantly develops and provides the delivery companies with billions of revenue. The courier and express delivery industry has been growing by annual 1% during the last five years from 2012 to 2017. The IBISWorld experts expect the demand for courier services to continue to increase over the next five years by 2022. This is caused by the growth of customer spending and demand for goods. Many companies are going to turn to air means of shipping in order to secure out on-time deliveries for the customers. There are almost 3 million employees and 600,000 companies on the market. The market size of the industry currently counts with $240 bln. According to the report by Accenture.com, the market of express deliveries is expected to grow from $237,9 bln in 2017 to $343,1 bln in 2020.
The number of start-ups contributing to sharing economy and attracting more investments grows annually. Investor interest rises to new features and possibilities that collaborative consumption can offer. Sharing goods and services, barter, rent makes people reflect not only on what they get but also how they get it. According to TIME Magazine's visionary article, collaborative consumption is one of 10 ideas that are going to change the world within the next 10 years. It is a new socio-economic model that is going to reshape consumption of services and goods. Although, there are prominent players in some sharing economy industries such as Airbnb in travelling, ZipCar in carsharing, Uber in taxi – the crowd shipping market is still at its very early stages of development.
Having analyzed problems that customers of courier and parcel delivery services usually face, our team came with the idea of Shipit and designed the project's main concept.
Let people ship your packages.
Shipit a mobile app that connects senders and travelers around the globe and provides them with cost-effective, fast, and reliable solution to deliver packages. Aside from that, it is an excellent tool to earn extra money while traveling. Shipit allows to set new delivery chains, to make complicated processes simpler, and to manage luggage more efficiently. It does not matter where you send your shipment, shipping will still be the most cost-effective and simple!
Shipit is a symbiosis of best ideas and practices of courier, crowdsource and crowdshipping services. We have synthesized the best business practices to create a revolutionary and unique service. Just as Uber and BlaBlaCar have already become a part of our daily lives, Shipit is going to become an irreplaceable tool for shipping items.
It is the first app of its' kind that uses smart contracts and blockchain as a native tool to make people lives easier all around the world. By implementing blockchain we want to build relations between participants based on transparency and safety, which should be an objective of any system. By integrating cryptowallet, we want to spare the app of any issues and restrictions related to fiat transactions.
Objective of Shipit is to create an alternative platform for express deliveries based on principles of sharing economy, blockchain and crowd shipping.
How It Works
The app is simple and intuitive. You just need to take a picture of an item you want to ship using your smartphone camera, input points A and B of your shipment's journey, set the size and value of item and the price you are willing to pay for the delivery. The system matches the input data with that of travelers and picks the best matches. Communicate with the candidates, pick the best one, hand off your item and track it upon delivery. Shipit verifies its users and monitors all shipments providing items' safety. Interactive interface makes the shipping simple and fast. You do not need to worry about making a mistake or missing important details.
Key Features
No customs charges or taxes, if the item fits green channel requirements.
Lower probability of theft or damage.
Shipping to individuals and legal entities.
Lower costs than when using delivery services.
Personal communication with delivering travelers.
No paperwork and bureaucracy.
Sender does not overpay for brand and promotion.
Sender's money is fairly distributed within the system instead of being transferred to corporations.
Travelers manage their luggage more efficiently.
Travelers contribute to the world.
Target Market
The Asia-Pacific Region (APAC) has long been a major focus for multinational enterprises, as the supply chains have been going through the process of globalization, and the demand of Western countries for Asian exports has been increasing. As the region shifts from an export-dependent economy to a customer-oriented one, the dynamics of logistics undergo changes as well. Local international supply chains once primarily constituted by dominating air and water freight companies have become a solid network of regional supply chains based on e-commerce. Unlike the US, the APAC market is fragmented and immature and is struggling to cope with huge demand. As a result, many retailers and e-commerce providers have created their own logistics solutions.
Despite the growth in online spending, the domestic supply chains in the Asia-Pacific Region are underdeveloped compared to its export supply chains. Some of the problems that the region is struggling with inadequate warehouse services, fragmented supply chains, poor technology and service, competition based exclusively on prices.
The Shipit team strongly believes that the Asia-Pacific Region is the most promising among the largest and developing markets. According to reports by experts from Accenture, the region's share in the near future will not only prevail over other regions of The World, but also will strengthen its position in general due to economic growth by 2020.
Boom the ICO Market with your project!
|Bitcoin Talk
|Hard Cap
|Soft Cap
|Token/Coin Name
|Preico Bonus
|Not Available
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|Not Available
|Preico Start Date
|August 01, 2018
|Preico End Date
|September 01, 2018
|Main ICO Start Date
|August 01, 2018
|Main ICO End Date
|September 01, 2018
|June 21, 2018
Honestly this project's actually very good, especially for those who are in the sending community and tourists, in addition to having earned a very big wage they also make extra money from Shipit while traveling. Extraordinary.
What you say's true.
However whether they aren't mistaken, Shipit gives incentives to those who have a fairly large wage. Well everything is their right as a developer it's up to them to do what.
The idea is good. Courier services are expensive and burocratic in most countries.
I don't think we should make a token for everything.. but it may work.
very good idea ,the project is unique. And the mpv also interesting. Hope will be best one.
One of the best and unique ICO is Shipit. It will help businesses and specially each people with business or don't have. Shipit is a symbiosis of best ideas and practices of courier, crowdsource and crowdshipping services.
Nice concept! this could be useful. Goodluck!
Another shipping platform that will be launching soon right? In my opinion, this kinds of platforms need large financial funds to support its project. Lets see what can it do in the future.
I like the ideal all planned.one of the major problem from cargo is expensive fee i hope you doing great to be success
This project reminds me of another ICO project that focuses in the shipping industry. Although, unlike the other ICO, this one is centered and is accompanied by a mobile app. The use and integration of the blockchain technology to the shipping services is a good idea, although, the adoption of its usage will be difficult as it aims to omit couriers.
This project reminds me of another ICO project that focuses in the shipping industry. Although, unlike the other ICO, this one is centered and is accompanied by a mobile app. The use and integration of the blockchain technology to the shipping services is a good idea, although, the adoption of its usage will be difficult as it aims to omit couriers.
Concepts are great. In this time courier service is much expensive. This project reduce that problem. One of the best project.
Already I heard another project for same specification bit know I don't mention the project name. My dought is unique projects are reach shortly on entire world. So this project reputation is little difficult in this scenario.
The project comes with excellent idea to perform better actions in shipping industry with just a mobile app and the travelers can make money while to traveling other destinations.
Read their whitepaper and this article thoroughly so it will impress you to invest in this project.
The idea is great, but the logistics of using travelers as couriers sounds a bit over reaching to me. Having traveled and knowing all the things that could go wrong, the likelihood of late shipments is hurdle unto itself.
i think this project have a good quality and very well on demand at moment
so this project very important
I got the idea of this. But it is still more convenient in ordinary courier company for me. But i like the idea of this project, it has so many benefits and I know most people will like it
Shipit is a place where you can deliver your items with the help of other shipit holder or member? This is a great idea giving an opportunity to others to earn and travel at the same time.
So this is more like a courier company then. There is nothing wrong if people try this as their courier in travelling abroad.
This is a great idea because Traveling is very indemand and convenient eveyday. I give 5 star!
In some countries people only need to dream of fast and safe parcels as the contingent of workers can never be ideal. Shipit will fix this problem completely. Very useful product is expected.
this is a good idea but am not sure if it will be implemented well. incase it does it will be a major success in shipping the industry.
There is nothing wrong with the ideas, concept and the main goals of this project. After I read and understood about it, I am very interested in what your project has to offers to us.
But I'm a bit pessimistic about the app you created to be realized.
This really looks like worse and the profiles on Linkedin...
There are already two of the projects got successful but...
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Yeah right. Huge claims to supply everyone with access...
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When we visit my sister in McAlester we always have to stop in at the Yellow Gazebo to see what is new. They have great toys, gifts, and decor items that you can't find anywhere else. Staff is friendly and helpful without being pushy.4


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Serafina Bar
Featuring luxurious furnishings and exuding elegance reminiscent of the Italian Renaissance, Serafina Bar offers a refined Venetian 'Bacaro' dining experience, a signature cocktail list and live entertainment in the evening.
Exuding a character reminiscent of the Italian Renaissance, Serafina Bar features lush furnishings, striking blown-glass chandeliers and a rich experience. With unique cocktails and small dishes inspired by Venetian 'Bacaro' cuisine, guests are encouraged to watch the sun set below the horizon whilst being serenaded by live entertainment in the evening. A selection of premium spirits and cigars is available to enhance the experience.
Serafina Bar hosts a daily happy hour from 6:00 p.m. to 8:00 p.m.
Please note: Serafina Bar is an adults only venue, welcoming guests aged 21 years or older.
All prices are inclusive of 7% municipality fee, 10% service charge and 5% VAT.
Be Social by Heinz Beck at Serafina
Serafina | Monday to Saturday | 7:00 p.m. - 11:00 p.m.
Sample the simplicity of Italy featuring an à la carte menu of epicureancuisine, complemented with a touch of Chef Heinz's signature cooking style. Showcasing dishes such as Beef Tartare with quail egg, Tortellini Burrata and tomato water, Fusilli cacio e pepe with peas foam to the decadent dessert Panna Cotta with Marsala Ice Cream, enjoy a casual relaxed evening with melodic live music.
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|Serafina Bar only welcomes guests 21 years old or older.
Children are not allowed
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- Hai-ling Qiao, Yu-Rong Hu, +4 authors Yu-Zhong Guo
- European Journal of Clinical Pharmacology
- 2005
Omeprazole, lansoprazole and rabeprazole have been widely used as proton pump inhibitors (PPIs). They can be metabolized in the liver by CYP2C19, a polymorphic enzyme, and have a wide… (More)
- Yu-Rong Hu, Hai-ling Qiao, Quan-cheng Kan
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AIM To study the kinetic characteristics of lansoprazole in healthy Chinese subjects in relation to CYP2C19 genotype status for the individualized dose regimen of lansoprazole. METHODS Nine… (More)
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Inspired by dew drops forming in natures garden the Aroma Dew ultrasonic diffuser is stylish with wood look base, colour changing lights and dew drop shape.
The cool mist technology uses ultrasonic waves to release the essential oils into the atmostphere in their 100% purist form so that the oils can be easily absorbed.
If you're looking for an elegant natural looking diffuser to create a relaxing feel in your home the Aroma Dew is perfect for you!
Ultrasonic Vaporisers use vibrations to retain essential oils in their 100% purest form, and once dispersed into the air they are easily inhaled and absorbed, offering health and healing benefits.
Unlike traditional vaporisers the Aroma Bloom uses no heat source and minimal water so there is NO condensation created making them safe for the whole family including babies and children to use.
Negative ions help remove dust, germs and bacteria in the air to assist with breathing, improving sleep and enhancing general wellbeing. The Aroma Bloom is great for children with asthma.
Purify the air in your home to remove allergies, stale air and odours. Our essential oil blends also have antibacterial properties, as these are dispersed into the atmosphere, will also assist to cleanse and clean the air and rid of air-borne bacteria.
The Aroma Bloom uses ultrasonic waves to create air moisture to combat the drying effects of heating and air-conditioning. This beautifies and moisturises the skin, and is ideal even in warmer climates and may assist making breathing easier during illness.
Each of the ultrasonic diffusers offer a slightly different lighting feature using healthy LED lighting. All diffusers can run with the light completely off (emitting no light at all).


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By implementing Simparel, Mamiye Brothers Inc., a leading manufacturer of children's and teen apparel, has improved its overall supply chain efficiencies, reduced their central costs, and has been able to tap into new distribution channels with ease.
"We managed to 'milk' our original ERP for 15 years, but over that span of time it became no longer a 'package solution' but a highly customized solution with many 'bolt-ons' that were costly and difficult to manage," explains David Cropper, CIO of Mamiye Brothers Inc.
Prior to implementing Simparel, Mamiye Brothers was using a legacy ERP solution that they had implemented over 15 years ago. The outdated solution did not provide the functionality today's fashion and apparel ERP solutions offer out-of-the-box, nor did it support the company's growth and expansion.
"To accommodate Mamiye's changing business model, the company resorted to "the bolt-on strategy", as have most fashion and apparel companies who have not made the change to a more modern, unified ERP solution like Simparel.
Since implementing Simparel's Unified Global ERP Solution for fashion and apparel manufacturers, Mamiye has been able to accommodate their growth and better manage their overall apparel supply chain.
The advanced technology and unified platform Simparel offers, has allowed Mamiye to 'tweak' their business model in order to tap into other distribution channels, which Cropper states would have been difficult in their old environment.
In addition to the achieving the agility to grow and expand their business, Mamiye decided to leverage cloud based computing (SaaS) to reduce their central costs. When evaluating their options, Mamiye decided that Simparel had the best SaaS option, offering the same flexibility, adaptability and functionality of a licensed solution.
"With Simparel, now we have a platform that allows us to move into the future rather than being constrained by the past. Simparel has helped us improve process efficiency and has given us the ability to tweak our business model to tap into other distribution channels that would have been difficult in our old environment," explains Cropper.
About Simparel
Designed specifically for the apparel, footwear, home furnishings and accessories industries, Simparel enables manufacturers to reach their full potential by accelerating performance across the entire company, as well as their global supply chain. The Simparel Unified Global ERP Solution provides global enterprise visibility and collaboration throughout the PLM, Supply Chain Management, Order-to-Cash, EDI, Logistics and Distribution processes.
True end-to-end functionality lets customers focus on products and sales by making business decisions faster and easier, improving product delivery, and facilitating cost and inventory management. This unified model approach has been proven to enable greater agility, flexibility and responsiveness.
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'We've lost a brother': Robert Costello remembered by former colleague
One of the two Fredericton police officers who died in the shooting that also killed two civilians Friday morning is being remembered as a constant source of cheer by a friend and former colleague.
Lawrence Robert Costello, 45, was a 20-year police veteran and is survived by his partner and four children.
This morning the most amazing man kissed me goodbye as he headed to work. This evening, I lay in our bed knowing that kiss will never happen again.
Dean Secord, past president of the New Brunswick Police Association, became friends with Costello while they served on the executive together.
"He was always cheerful, no matter what was going on, [he] was always the person thinking positive. It was great working with him," said Secord.
Secord retired from the Saint John Police Force in March after serving for nearly 30 years.
As he and Costello got to know each other, they realized they had both gone to school in Sussex together.
Dean Secord, past president of the New Brunswick Police Association, says Robb always had a positive attitude. (CBC)
Secord said the news of his friend's death Friday mid-morning was difficult, and he spent the day remembering Costello.
"I've got a knot in my stomach and it won't go away" said Secord.
Secord said the loss is compounded by the fact that Costello was so positive and wanted to make change in the community.
"It's a big loss, not only to the policing community," said Secord. "We've lost a friend. We've lost a brother."
Secord acknowledged that he is just one of many people who cared for Costello. He said his heart goes out to both his and Sara Burns' friends, colleagues, and family.
Burns is the other police officer who was killed in the shooting on Friday. Burns, 43, joined the Fredericton Police Force in 2016 but previously served as an auxiliary officer for two years. She was married with three children.
Secord said he hasn't reached out to Costello's family yet, despite having met his partner a few times. He said he doesn't want to overwhelm them but will reach out in due time.
Police officers Robert Costello, 45, and Sara Burns, 43 were killed in the north-side shooting in Fredericton on Friday morning. (Fredericton Police Force/Twitter)
"Somebody has lost a son and a husband and a father. And a wife, and a mother. So it's a big loss overall to the community."
He said it will be a tough time in Fredericton over the next few weeks.
"We'll grieve, we'll get through this horrible tragedy," said Secord. "Robb's now looking down upon us."Read more


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CHMP Issues a Positive Opinion on Janssen's ZYTIGA® to Include Earlier Stage Prostate Cancer Patients
Janssen-Cilag International NV ("Janssen") today announced that the European Medicines Agency's (EMA) Committee for Medicinal Products for Human Use (CHMP) has recommended broadening the existing marketing authorisation for ZYTIGA® (abiraterone acetate) plus prednisone / prednisolone to include an earlier stage of prostate cancer than its current indications. If approved by the European Commission, abiraterone acetate plus prednisone / prednisolone in combination with androgen deprivation therapy (ADT) can be used for the treatment of adult men with newly diagnosed high-risk metastatic hormone-sensitive prostate cancer (mHSPC).1
"As shown by the results from the LATITUDE study, adding abiraterone acetate plus prednisone / prednisolone to ADT alone significantly improves overall survival and radiographic progression-free survival in men with metastatic hormone-sensitive prostate cancer and high-risk features in comparison to treating patients with ADT alone, where median survival is currently less than three years. Today's decision means we are one step forward in ensuring mHSPC men across Europe may be able to benefit from this treatment soon," said Professor Karim Fizazi, principal investigator of the LATITUDE trial and Head of the Medical Oncology Department at Institute Gustave Roussy.
The CHMP recommendation is based on data from the multinational, multicentre, randomised, double-blind, placebo-controlled Phase 3 study, LATITUDE. The trial was designed to determine if newly diagnosed patients with mHNPC who have high-risk prognostic factors benefit from the addition of abiraterone acetate and prednisone to androgen deprivation therapy (ADT) vs placebos and ADT.2 Data were presented at the 2017 American Society of Clinical Oncology congress in Chicago, USA and published in the New England Journal of Medicine.
"We are very pleased with the CHMP's decision which recommends abiraterone acetate plus prednisone / prednisolone in combination with ADT for use in adult patients with newly diagnosed high-risk metastatic hormone-sensitive prostate cancer. Janssen Oncology has played a significant role in transforming the way prostate cancer is treated so far and aims to continue this progress," said Dr. Ivo Winiger-Candolfi, Oncology Solid Tumor Therapy Area Lead, Janssen Europe, Middle East and Africa.
Abiraterone acetate plus prednisone / prednisolone has already been approved by the European Commission (EC) for the treatment of metastatic castration-resistant prostate cancer (mCRPC) in adult men who are asymptomatic or mildly symptomatic after failure of ADT in whom chemotherapy is not yet clinically indicated and of mCRPC in adult men whose disease has progressed on or after a docetaxel-based chemotherapy regimen.3
In the LATITUDE study, the safety profile of ADT in combination with abiraterone acetate plus prednisone was consistent with prior studies in patients with metastatic castration-resistant prostate cancer (mCRPC). Most common adverse events were elevated incidences of mineralocorticoid-related hypertension and hypokalemia in the ADT in combination with abiraterone acetate plus prednisone arm compared with ADT and placebos.4 The observed degrees of hypertension and hypokalemia were both medically manageable with antihypertensive medications and potassium supplements as needed, only rarely required treatment discontinuation, and seldom led to serious consequences.4
The CHMP's Positive Opinion will now be reviewed by the European Commission, which has the authority to grant approval of the new indication.
About high-risk metastatic hormone-sensitive prostate cancer (mHSPC)
Not all prostate cancer is the same. It ranges from cancer confined to the prostate gland to cancer that has spread outside of the prostate to the lymph nodes, bones, or other parts of the body. The extent or spread of prostate cancer determines its stage.5 Hormone-sensitive prostate cancer (HSPC) refers to a stage of the disease when the patient is still sensitive to treatment with ADT.6 Patients with newly diagnosed mHSPC, particularly with high-risk characteristics, have a poor prognosis. ADT plus docetaxel has shown improved outcomes in mHSPC when compared to ADT alone, but many patients are not candidates for docetaxel and may benefit from alternative therapy.7 Also, while the majority of patients initially start on ADT, it usually becomes less effective over time.8,9,10
About the LATITUDE Trial 2
The Phase 3, multinational, multicentre, randomised, double-blind, placebo-controlled LATITUDE study enrolled 1,199 newly diagnosed patients with metastatic hormone-naïve prostate cancer (mHNPC) and was conducted at 235 sites in 34 countries in Europe, Asia-Pacific, Latin America, and Canada. A total number of 597 patients were randomised to receive ADT in combination with abiraterone acetate plus prednisone (n=597), while 602 patients were randomised to receive ADT and placebos (n=602). Patients included had high-risk mHNPC documented by positive bone scan or metastatic lesions at the time of diagnosis on computed tomography (CT) or magnetic resonance imaging (MRI). Additionally, patients had to have at least two of the three following high-risk factors associated with poor prognosis:2
- Gleason score ≥8
- ≥3 bone lesions
- presence of measurable visceral metastases
These results served the basis for Janssen's Type II variation application submission to the European Medicines Agency (EMA), seeking to expand the existing marketing authorisation for abiraterone acetate plus prednisone or prednisolone to include the treatment of adult men with newly-diagnosed, high-risk metastatic hormone-sensitive prostate cancer (mHSPC). If approved, this will broaden the use of abiraterone acetate plus prednisone / prednisolone to include an earlier stage of prostate cancer than its current indications.
Overall, the safety profile of ADT in combination with abiraterone acetate plus prednisone was consistent with prior studies in patients with metastatic castration-resistant prostate cancer (mCRPC). Most common adverse events were elevated incidences of mineralocorticoid-related hypertension and hypokalemia in the ADT in combination with abiraterone acetate plus prednisone arm compared with ADT and placebos. The incidence rate of grade 3 or higher hypertension (20% vs. 10%) was greater than that observed in prior studies of abiraterone acetate in mCRPC patients. There were no serious sequelae from the increased rate of hypertension. The incidence of hypokalemia was higher than that reported in prior Phase 3 studies of abiraterone acetate plus prednisone in mCRPC; however, only two patients discontinued treatment due to hypokalemia and there were no hypokalemia-related deaths. Mineralocorticoid-associated adverse events were generally medically manageable.
About abiraterone acetate
Abiraterone acetate plus prednisone / prednisolone is the only approved therapy in mCRPC that inhibits production of androgens (which fuel prostate cancer growth) at all three sources that are important in prostate cancer - the testes, adrenals and the tumour itself.3,11,12
Indications 3
In 2011, abiraterone acetate in combination with prednisone / prednisolone was approved by the European Commission (EC) for the treatment of mCRPC in adult men whose disease has progressed on or after a docetaxel-based chemotherapy regimen.
In December 2012, the EC granted an extension of the indication for abiraterone acetate permitting its use, in combination with prednisone or prednisolone, for the treatment of mCRPC, in adult men who are asymptomatic or mildly symptomatic after failure of androgen deprivation therapy in whom chemotherapy is not yet clinically indicated.3
Further Information 3
The most common adverse reactions seen with abiraterone acetate plus prednisone / prednisolone include urinary tract infection, hypokalemia, hypertension, and peripheral oedema.
For a full list of side effects and for further information on dosage and administration, contraindications and other precautions when using abiraterone acetate plus prednisone / prednisolone please refer to the summary of product characteristics, which is available at: http://www.ema.europa.eu/docs/en_GB/document_library/EPAR_-_Product_Information/human/002321/WC500112858.pdf
About the Janssen Pharmaceutical Companies
At the Janssen Pharmaceutical Companies of Johnson & Johnson, we are working to create a world without disease. Transforming lives by finding new and better ways to prevent, intercept, treat and cure disease inspires us. We bring together the best minds and pursue the most promising science. We are Janssen. We collaborate with the world for the health of everyone in it. Learn more at www.janssen.com/emea. Follow us on http://www.twitter.com/janssenEMEA for our latest news.
Cilag GmbH International; Janssen Biotech, Inc.; Janssen Oncology, Inc. and Janssen-Cilag International NV are part of the Janssen Pharmaceutical Companies of Johnson & Johnson.
Cautions Concerning Forward-Looking Statements
This press release contains "forward-looking statements" as defined in the Private Securities Litigation Reform Act of 1995 regarding the continued development and potential of abiraterone acetate plus prednisone / prednisolone. The reader is cautioned not to rely on these forward-looking statements. These statements are based on current expectations of future events. If underlying assumptions prove inaccurate or known or unknown risks or uncertainties materialise, actual results could vary materially from the expectations and projections of Janssen-Cilag International NV, any of the other Janssen Pharmaceutical Companies and/or Johnson & Johnson. Risks and uncertainties include, but are not limited to: challenges and uncertainties inherent in product research and development, including the uncertainty of clinical success and of obtaining regulatory approvals; uncertainty of commercial success; manufacturing difficulties and delays; competition, including technological advances, new products and patents attained by competitors; challenges to patents; product efficacy or safety concerns resulting in product recalls or regulatory action; changes in behaviour and spending patterns or financial distress of purchasers of health care products and services; changes to applicable laws and regulations, including global health care reforms; and trends toward health care cost containment. A further list and descriptions of these risks, uncertainties and other factors can be found in Johnson & Johnson's Annual Report on Form 10-K for the fiscal year ended January 1, 2017, including under "Item 1A. Risk Factors," its most recently filed Quarterly Report on Form 10-Q, including under the caption "Cautionary Note Regarding Forward-Looking Statements," and the company's subsequent filings with the Securities and Exchange Commission. Copies of these filings are available online at www.sec.gov , www.jnj.com or on request from Johnson & Johnson. Neither the Janssen Pharmaceutical Companies nor Johnson & Johnson undertakes to update any forward-looking statement as a result of new information or future events or developments.
1 European Medicines Agency. ZYTIGA CHMP meeting highlights. Available at: http://www.ema.europa.eu/docs/en_GB/document_library/Summary_of_opinion/human/002321/WC500236610.pdf. Last accessed October 2017.
2 National Institutes of Health. A Study of Abiraterone Acetate Plus Low-Dose Prednisone Plus Androgen Deprivation Therapy (ADT) Versus ADT Alone in Newly Diagnosed Participants With High-Risk, Metastatic Hormone-Naive Prostate Cancer (mHNPC). Available at: https://clinicaltrials.gov/show/NCT01715285 . Last accessed October 2017.
3 ZYTIGA® summary of product characteristics (February 2017). Available at: http://www.ema.europa.eu/docs/en_GB/document_library/EPAR_-_Product_Information/human/002321/WC500112858.pdf. Last accessed October 2017.
4 Fizazi, K. et al. Abiraterone plus Prednisone in Metastatic, Castration-Sensitive Prostate Cancer. New England Journal of Medicine 2017; 377:352-360.
5 Prostate Cancer Foundation. Staging the disease. Available at: https://www.pcf.org/c/staging-the-disease/ Last accessed October 2017.
6 Moul, J.W. Hormone naïve prostate cancer: predicting and maximizing response intervals. Available at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4814946/. Last accessed October 2017.
7 Engel Ayer Botrel, T. Efficacy and Safety of Combined Androgen Deprivation Therapy (ADT) and Docetaxel Compared with ADT Alone for Metastatic Hormone-Naive Prostate Cancer: A Systematic Review and Meta-Analysis. Available at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4911003/. Last accessed October 2017.
8 Gillessen S, et al. Management of patients with advanced prostate cancer: recommendations of the St Gallen Advanced Prostate Cancer Consensus Conference. Ann Oncol. 2015;26:1589-1604.
9 Cornford P, et al. Guidelines on Prostate Cancer. Part II: treatment of relapsing, metastatic, and castration-resistant prostate cancer. Eur Urol. 2017;71:630-642.
10 American Cancer Society. "Treating Prostate Cancer That Doesn't Go Away or Comes Back After Treatment." Available at: https://www.cancer.org/cancer/prostate-cancer/treating/recurrence.html. Last accessed October 2017.
11 Hoy, SM. et al. Abiraterone Acetate: A review of its use in patients with metastatic castration-resistant prostate cancer drugs. Drugs 2013; 73:2077-2091.
12 Ritch, CR. Cookson, MS. Advances in the management of castration resistant prostate cancer. BMJ. 2016 Oct 17;355:i4405. Doi: 10.1136/bmj.i4405.
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Maxion Wheels to Showcase Market-Leading Light Weight Commercial Vehicle Wheels at REIFEN 201816.8.2018 04:05 | Pressemelding
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La isla de Martha's Vineyard y otros lugares
David Hockney
AbeBooks Seller Since May 26, 2003Quantity Available: 1
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About this Item
Bibliographic Details
Title: La isla de Martha's Vineyard y otros lugares
Publisher: Ediciones Poligrafa, Barcelona
Publication Date: 1985
Binding: Hardcover
Book Condition:Very Good
Dust Jacket Condition: No Jacket
About this title
Contains a 32 page booklet with an explanatory text in Spanish and 150 pages from a sketchbook, as well as a slipcase with an opuscule and a facsimile edition of the sketchbook.
"About this title" may belong to another edition of this title.
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Black Friday Deals 12A.D. Nike Kobe A.D. Navy Blue Kobe 12, PriceVitamin E – For overall health Vitamin E, a fat-soluble vitamin, has antioxidant properties. Antioxidants help your body fight infections. Vegetable oils contain vitamin E. Ask your registered dietitian (RD) about other sources of vitamin E.
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A healthy diet is an important part of your care Eating a well-balanced diet containing a variety of foods is the best way to meet your vitamin needs. If your vitamin requirements cannot be met through food alone, you may require a multivitamin supplement. Ask your CF Center registered dietitian (RD) to determine which vitamin supplement is best for you.
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meet the Step 1 & with 5000 IUs of D3 and other fat soluble vitamins to meet the Step 2 increase in patients with low vitamin D levels.
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Read more
NEW Patient Assistance Program...
Have you heard about the NEW Patient Assistance Program that pays for vitamins? If not read on, as this outlines four important program areas: ELIGIBILITY, COVERAGE, ENROLLMENT and FULFILLMENT.
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Upcoming Car Mercedes-Benz E-Class All-Terrain Review
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The Launch of Suzuki Burgman Street
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Pre-bookings for BMW G310 R and G310 GS open in India
BMW has announced to open pre-bookings for two of its motorcycles. Both the anticipated motorcycles will be available in India…Read More »


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Arnold Battle of Columbus First Official Competition Qualifier
Hi to all Martial Arts Community Family members,
We are excited to announce that the Arnold Battle of Columbus World Games is establishing the qualifier circuit to promote the Arnold Battle of Columbus 2019 World Games.
The Arnold Battle of Columbus (ABOC) has succeeded for 42 years with integrity and reputation, it wouldn't be possible without all of your dedication and commitment.
I'd like to ask you again to take a positive leadership role for this very first ABOC qualifier on September 8th, 2018 here in Columbus.
Please review the attached poster above with information and register as soon as possible. The online registration form will be up very soon.
Please post this info to all available forums and encourage your students to register to participate, let it begin with your registration first.
Thank you all again for your continuous support.
Yours truly,
2018 Meditation For July BB Test
Sunday, 6/24, over 40 OMAC branches black belt students up to 8th dan completed 12 hours of meditation. The test coming on July 19-22 at Kenyon college during the 37th annual OMAC summer camp.
They completed 3-6 days of fasting prior to 12 hours meditation on Sunday. Sgm Choi leading the last phase of meditation. Congratulations to all OMAC instructors and students. This tradition has been started since 1971 after young master Choi brought taekwondo in the USA.
The Oriental Martial Arts College (OMAC)
Founded in 1963 in Korea, moved to USA in 1971
(Affiliated with: USAT, Kukkiwon, WTF, Taekwondo-won, Songmookwan)
Founder/President Grand Master Joon P. Choi
· 10th Degree Black Belt with 60 years Experience
· Trained FBI, Swat, Secret Service, Navy Seal,
OSU Football Team 1991
· Coached U.S. Taekwondo Team in 1988 Seoul Olympic (11 medals)
· Trained over 25,000 Students
· Produced over 20 U.S. National Champions & Olympic winners
· Over 100 Certified Instructors
Our Vision KYO:
Kids Grow Up Happy & Healthy, Young Become Wise & Strong,
Old enjoy peace and harmony
Our Mission ETAT: Education, Training, Application, Teaching
Our Greatest Common Goal: Self-improvement for Success & Happiness
OMAC's 4 Process of Developing an Holistic Life Skills
1. Education (Mental Exercise)
2. Training (Physical & Mental Exercise)
3. Applying (Application of Holistic Life Skills in everyday Life)
4. Teaching (Confirming own Skills & Promoting Positive Self
by Teaching)
OMAC's Success Formula (True Partnership) :
Good Parents + Good Teachers + Good Life Skills = A Bright Future
OMAC's holistic skills focus on personal growth through development of the mind, body, spirit, and emotion of the Moogong Warrior, the OMAC student practitioner. Fundamental to this growth and development are some of the first "Words of Wisdom" that all students are required to learn: innae, geukki, joen gyung, shin-nyum, sarang... patience, discipline, respect, confidence, love.
OMAC Central Ohio has 9 branches and clubs throughout Columbus, Reynoldsburg, Westerville, Minerva Park, Worthington, Dublin, Gahanna, New Albany, Hilliard, and Franklin County to provide you the greatest opportunities to learn martial arts in Central Ohio, close to your home. We offer multiple taekwondo classes each day, each designed for different ages (youth, adult), skill levels (beginner, advanced), and skill focus (sparring, conditioning, forms, self defense), although a student is free to attend any (or all) of these classes. We also offer other disciplines such as Gumdo, Hapkido, and Kimoodo on certain nights of the week.
OMAC Quick Facts
Sr. Grand Master Joon P. Choi started OMAC in 1971 and has taught over 25,000 students, including nearly twenty US national champions and four Olympic participants.
Sr. Grand Master Joon P. Choi coached the American Olympic Taekwondo Team in taekwondo's first Olympic games: 1988.
OMAC's World Headquarters has been in Reynoldsburg, OH for 26 years.
Sr. Grand Master Choi is a two time Korean National Champion.
OMAC Main Programs: Taekwondo, Karate, Kung Fu, Hapkido, Weapons, Little Tigers, Kimoodo, Women's Self Defense, Wushu/Kung Fu/Tai Chi, and Instructor/Referee Certification.
OMAC Major Events:
* Winter Camp/Big Bow Ceremony
* Arnold World Sports Festival
Taekwondo Championships
* Spring Camp
* Battle of Columbus Martial Arts World Games/Asian Festival
* Summer camp
* Buckeye Classic Taekwondo-
Martial Arts Championship with
Ohio State Fair
* International Exchange - Europe & Asia
* Fall Camp
* Halloween & Inter School
Take a look around.


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9375 Whitley Dr
Indianapolis, IN 46240-1349
Sales: (317) 573-0200
Nav System, Heated Seats, Moonroof, iPod/MP3 Input, CD Player, Back-Up Camera, Aluminum Wheels, HEAD-UP DISPLAY. FUEL EFFICIENT 33 MPG Hwy/23 MPG City! 430i xDrive trim, Jet Black exterior and Coral Red Dakota Leather interior SEE MORE! KEY FEATURES INCLUDE Sunroof, All Wheel Drive, Power Liftgate, Rear Air, Back-Up Camera, Turbocharged, iPod/MP3 Input, CD Player, Onboard Communications System, Aluminum Wheels, Keyless Start, Dual Zone A/C. Remote Trunk Release, Keyless Entry, Steering Wheel Controls, Child Safety Locks, Electronic Stability Control. OPTION PACKAGES PREMIUM PACKAGE Heated Front Seats, Remote Services, Advanced Real-Time Traffic Information, Navigation System, Instrument Cluster w/Extended Contents, Lumbar Support, HEAD-UP DISPLAY. BMW 430i xDrive with Jet Black exterior and Coral Red Dakota Leather interior features a 4 Cylinder Engine with 248 HP at 5200 RPM*. VEHICLE REVIEWS The 2018 4 Series takes the agility, acceleration and balance of the 3 Series and strengthens it with a wider stance and lower center of gravity. -KBB.com. Great Gas Mileage: 33 MPG Hwy. MORE ABOUT US We are a Five Time Center of Excellence Award Winning Dealership. We achieved this award in '10, '11, '12, '13, and '15. Discover the Dreyer Reinbold Difference. You'll be very glad you did. Horsepower calculations based on trim engine configuration. Fuel economy calculations based on original manufacturer data for trim engine configuration. Please confirm the accuracy of the included equipment by calling us prior to purchase.
9375 Whitley Dr
Indianapolis, IN 46240-1349
(0 Miles)
Sales: (317) 573-0200
Year: 2018
Make: BMW
Model: 430i xDrive
Price: $45,900
Mileage: 4,863
Engine: I-4 cyl
Transmission: AUTOMATIC
Exterior Color: Jet Black
Interior Color: Coral Red Dakota Leather
Fuel Type: Other
Stock #: 26968
City MPG: 23
Hwy MPG: 33
Featured Options
Essentials Package
Premium Package
Matte Chrome Exterior Trim
Fineline Anthracite Wood Trim
Head-up Display
Included Packages
Essentials Package
Premium Package
Sport Line
Additional Options
Matte Chrome Exterior Trim
Head-up Display
CO2 relevant vehicles
Sport Automatic Transmission
Tire pressure monitor
Alarm System
Universal garage-door opener
Exterior parts in body color
Rear view camera
Without Lines designation
Floor mats
Auto-dimming mirrors
Auto-dimming rearview mirror
Power Front Seats
Split fold-down-rear seat
Storage package
Rain sensor and auto headlight
Automatic climate control
Additional 12-V power sockets
LED Fog Lights
Hi-fi sound system
DVD Area coding, North America
BMW Assist eCall
BMW TeleServices
ConnectedDrive Services
Instrument cluster
Anthracite headliner
Oil Chg 10,000 mls/12 months
Daytime driving lights
Shipping package
Transport protection
Tier 2
BMW First Aid Kit


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12555, NY Rent to Own Homes
|345 Listings Found
Prime Location-High Visibility! Street side currently rented as Nail Salon and rear portion is a 2
42 Quassaick Avenue, New Windsor, NY, 12553Details »
Location, Location, Location. This absolutely stunning 1890 Victorian with a wraparound front porch sits twelve mile from the Beacon...
1203 North Avenue, Beacon, NY, 12508Details »
-to-date appliances & one air conditioned unit. Most affordable -beats paying rent! Monthly HOA includes: taxes
10 Oakwood Terrace(105, New Windsor, NY, 12553Details »
This beautiful newly restored 24 x 40 Pinegrove manufactured home is located in a well-kept mobile home park with high ratings and is...
27 Oriole Circle, Newburgh, NY, 12550Details »
Vacant land suitable for commercial development for sale or lease. Located on Route 17K close to I
253 Route 17k, Newburgh, NY, 12550Details »
includes fifteen fully rented units with a Gross Rental Income of $197,100. Most units have been
99 Dubois St, Newburgh, NY, 12550Details »
Great for investors! two apartments rented- top floor New Windows. Private parking in back
170 First St, Newburgh, NY, 12550Details »
Airport. 60 mis to NYC. Lots of storage in basement & easy pull-down attic. Live in or rent out â?? great
14 Parkview St, Newburgh, NY, 12550Details »
St, Newburgh, NY 12550four Bedrooms two Bathrooms 960 sq/ft Lot 1306 sq/ft 2 Family, fully rented
58 Grove St, Newburgh, NY, 12550Details »
sure to be a wonderful place to rent and live out the other floor. A front porch for 1 device
43 Beacon St 3200 Square, Newburgh, NY, 12550Details »
and 2 1 beds units. Fully rented with month to month leases. Parking on premises for eight cars plus
702 Broadway, Newburgh, NY, 12550Details »
acres with two older homes on the property that are rented out. Located with-in five minutes to all
Newburgh, NY, 12550Details »
the building and rent the other half. Possibilities are endless. (Listing 6751110 Confirmed 8/19/2018.)
446 South Plank (Route 52 Rd, Newburgh, NY, 12550Details »
of multi-family and mixed use properties. The portfolio includes 29 fully rented units with a Gross Rental
283 Washington St, Newburgh, NY, 12550Details »
Assesment has been reduced to $224,000. Calling all professionals! Why pay rent when you can buy
313 Fullerton Ave, Newburgh, NY, 12550Details »
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Info Ice And Fire Double Edged
Online Game instruction
Use your mouse and keyboard to play this game.
Previous game Save Chieftain
Next game Tom And Jerry Escape
Use your mouse and keyboard to play this game.
Previous game Save Chieftain
Next game Tom And Jerry Escape
Mona loves spring so she thought to embrace the season of Renaissance with joy and good attitude. She wants to look completely perfect in order to match with the good spirit of spring. Take a look into her wardrobe and choose the dress you like the most. Remember it has to be a springlike dress. ...
Roleplay as a Strong Warrior Hero on a Quest to save the Village from the Perils of the Evil Chaos Monster Clan. Defeat the monsters and level up by gaining experience points for each battle won. You can customize the Hero's name.
Emma is very honored to attend the annual party that her boss is throwing. It is a select party, with sophisticated dress code and could use your fashion skills to dress her breathtaking. She went to Milan to acquire a stylish dress but she cannot decide which one to wear. Dress her with few mode...
Jerry is on the hunt for cheese again, Help Jerry collect all the cheese to pass the level. Watch out for the spikes are you will fail. Have fun playing Jerry and Cheese. Use your mouse to draw a line to the cheese.
Play An exciting bike challenge game. Ride your bike and clear the obstacles to complete the level. Collect coins to score points. All the best! Use your mouse to play this game.
Its time to perform some crazy stunts, get on your dare devil bike and show some dare stunts. Use your mouse and keyboard to play this game.
In many parts of West Africa and India, many kids grow up playing the Rubber band game. It's like hide and seek, or paintball in the United states. Basically kids split into different teams, usually two, then they go into hiding already equipped with their shield and armor (casual clothing, mask,...
Girls, come here to experience the exciting moment! Wow, beautiful wedding dress, stylish hairstyle, pretty accessories and good-looking veil. They are so attractive. Do not forget to select a bouquet of roses. Furthermore, you could even color the background, gowns, hairs and flowers. Now, your ...


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This property has been removed by the agent. It may be sold or temporarily removed from the market
4 bedroom detached house for saleConiston Drive, Holmes Chapel
Sold STC
Property Description
Key features
- Detached family home being within walking distance to the high school
- Extended to create substantial living accommodation
- Three reception rooms including a large sitting/dining room with log burning stove
- Open plan living dining kitchen with doors onto the garden
- large utility room and downstairs wc
- Four bedrooms to the first floor along with a four piece white bathroom suite
- Ample off road parking to the front
- Private lawned rear garden
Full description
Ideally situated within walking distance of Holmes Chapel Comprehensive School, a four bedroom detached home with three reception rooms along with an open plan living dining kitchen.
This detached family home is ideally situated being within a short walk of Holmes Chapel Comprehensive School along with the village centre with all its amenities.
Having been extended over the years to create spacious living accommodation which comprises of three reception rooms - Study/play room, living room and a sitting/dining room to the rear with a log burning stove. The open plan living dining kitchen has ample space for a sitting area and a dining area, with doors opening to the rear garden. A downstairs wc and a large utility room provides ample storage space.
To the first floor there are four bedrooms along with the family bathroom which is fitted with a four piece white suite.
Externally, the front provides off road parking for several vehicles, while the rear garden is mainly laid to lawn with fence boundaries, all offering a great degree of privacy.
A fantastic family home which must be viewed to be appreciated.
More information from this agent
To view this media, please visit the on-line version of this page at www.rightmove.co.uk/property-for-sale/property-70724819.html?premiumA=true
Energy Performance Certificates (EPCs)
To view this media, please visit the on-line version of this page at www.rightmove.co.uk/property-for-sale/property-70724819.html?premiumA=true
Listing History
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Map & Street View
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Market Info
Disclaimer - Property reference 495687. The information displayed about this property comprises a property advertisement. Rightmove.co.uk makes no warranty as to the accuracy or completeness of the advertisement or any linked or associated information, and Rightmove has no control over the content. This property advertisement does not constitute property particulars. The information is provided and maintained by Gascoigne Halman, Holmes Chapel. Please contact the selling agent or developer directly to obtain any information which may be available under the terms of The Energy Performance of Buildings (Certificates and Inspections) (England and Wales) Regulations 2007 or the Home Report if in relation to a residential property in Scotland.
* Average speeds are based on the download speeds of at least 50% of customers at peak time (8pm to 10pm) from packages available on comparethemarket.com. Speed can be affected by a range of technical and environmental factors. The speed you receive where you live may be lower than that listed above. You can check the estimated speed to your property prior to purchasing. Fibre/cable services at your postcode are subject to availability. You can confirm availability on the provider's website. Providers may increase charges. You should have the right to exit your contract without penalty if this happens. The information is provided and maintained by Decision Technologies Limited.
Map data ©OpenStreetMap contributors.


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The hexadecimal color code #0f473a is a dark shade of green-cyan. In the RGB color model #0f473a is comprised of 5.88% red, 27.84% green and 22.75% blue. In the HSL color space #0f473a has a hue of 166° (degrees), 65% saturation and 17% lightness. This color has an approximate wavelength of 501.64 nm.
They always say time changes things, but you actually have to change them yourself.

…

It is not the language of painters but the language of nature which one should listen to, the feeling for the things themselves, for reality, is more important than the feeling for pictures.

…

For me, painting is a way to forget life. It is a cry in the night, a strangled laugh.

…


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Edu-Care Recycling Uk
Beech effect left hand desk
We currently have 9 in stock.
Beech effect left hand desk with push-fit metal legs
1600cm wide
80-120cm deep
73cm high
As all of our items are recycled from office clearances, they may show marks and signs of use. All items are cleaned before entering our warehouse and showroom. We can deliver locally for an additional cost (please contact us for more information) or buyer can collect for free from us.
Opening hours are 9.00am to 5.00pm, Monday to Friday.


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About this pro
21 years in business
5 hires on Thumbtack
1 employee
Justine R.Feb 14, 2018Verified
Tamiza S.
So far we are coming up with concepts for my collection. Matt responded in a timely manner. Is very warm and friendly. Also very knowledgeable. I am beyond grateful I found him through Thumbtack. We are going to create some wonderful masterpieces! Photos to follow in the near future...Jan 9, 2018Verified
Angelina S.
This designer really has the creative capacity to make something amazing whatever the idea may be. I am currently having him make a mermaid gown costume for me and it is turning out so very beautiful. He is flexible with your schedule which I appreciate and he pays attention to every detail big or small. Professional and talented so look no further!Oct 13, 2017Verified
Thumbtack Customer
Has a clear punctuality and valueNov 21, 2017
Megan P.
Project will start in November.Sep 25, 2017Verified


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