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Merus Announces First Patient Dosed in a Phase 2 Clinical Trial of MCLA-128 in Two Metastatic Breast Cancer Patient Populations
Combination trial to evaluate MCLA-128 in HER2-positive and hormone receptor-positive/HER2-low metastatic breast cancer patients
UTRECHT, the Netherlands, Jan. 26, 2018 (GLOBE NEWSWIRE) -- Merus N.V. (Nasdaq:MRUS), a clinical-stage immuno-oncology company developing innovative bispecific antibody therapeutics (Biclonics®), today announced that the first patient has been dosed in a Phase 2, open-label, multi-center international clinical trial to evaluate MCLA-128 in two metastatic breast cancer (MBC) populations including HER2-positive MBC patients and hormone receptor positive/HER2-low MBC patients.
MCLA-128 is a full-length IgG bispecific antibody with enhanced antibody-dependent cellular cytotoxicity (ADCC) targeting HER2 and HER3 receptors. MCLA-128 blocks the HER3 signaling pathway by employing a Dock & Block(TM) mechanism. MCLA-128 is designed to dock onto a specific region of the HER2 receptor to orientate MCLA-128's HER3 binding arm to block HER2:HER3 heterodimerization. Oncogenic signaling through the HER3 pathway, even in the presence of high heregulin concentrations, may thus be effectively blocked.
"Initiation of the Phase 2 clinical trial in patients with HER2-positive MBC populations and hormone receptor-positive/HER2-low MBC populations represents another key milestone for Merus," said Ton Logtenberg, PhD., Chief Executive Officer. "With promising single agent activity observed in heavily-pretreated patients underscoring the potential of MCLA-128 in MBC, this study is designed to elucidate the activity of this important HER2/HER3-targeted candidate in combination with current standards of care in areas of unmet need. Concurrently, our study evaluating single agent activity for MCLA-128 in gastric, ovarian, endometrial and non-small cell lung (NSCL) cancers is ongoing and we anticipate defining a clinical plan for MCLA-128 in solid tumors beyond metastatic breast cancer starting the second quarter of 2018. In addition, we remain committed to the remainder of our pipeline candidates, including MCLA-117 in acute myeloid leukemia, which is currently in the clinic, MCLA-158 for the potential treatment of colorectal cancer, which we expect to enter the clinic in the first quarter of 2018, as well as MCLA-145, which we are developing with Incyte Corporation in solid tumors."
The MCLA-128 Phase 2 clinical trial is expected to enroll approximately 120 patients in total across the U.S. and Europe. The first cohort, HER2-positive MBC patients who are progressing on anti-HER2 therapies including TDM-1, will receive MCLA-128 in combination with trastuzumab and chemotherapy. In preclinical studies, synergistic activity of MCLA-128 and trastuzumab has been demonstrated to inhibit heregulin-driven tumor cell growth. The second cohort, MBC patients with confirmed hormone receptor positive status and HER2-low (immuno-histo-chemistry (IHC) HER2 1+ or 2+ and fluorescent in-situ hybridization (FISH) negative for HER2 amplification) who are progressing on hormone therapies and CDK4/6 inhibitors, will receive MCLA-128 in combination with endocrine therapy. In preclinical models, blocking of signaling through the HER3 pathway has been shown to synergize with endocrine therapy. The primary endpoint for both cohorts is the clinical benefit rate at 24 weeks. Additional details about the study can be found on ClinicalTrials.gov, using identifier NCT: NCT03321981.
About MCLA-128
MCLA-128 is designed to block HER3/heregulin-dependent tumor growth and survival as well as enhance immune-mediated cytotoxicity in tumors. MCLA-128 employs a Dock and Block(TM) mechanism in which the mode of HER2 receptor binding orientates the HER3 binding arm to effectively block oncogenic signaling through the HER2:HER3 heterodimer even under high heregulin concentrations. In addition, MCLA-128 is modified for enhanced ADCC in order to recruit and activate immune effector cells to directly kill tumor cells.
About Merus N.V.
Merus is a clinical-stage immuno-oncology company developing innovative full-length human bispecific antibody therapeutics, referred to as Biclonics®. Biclonics®, which are based on the full-length IgG format, are manufactured using industry standard processes and have been observed in preclinical and clinical studies to have several of the same features of conventional human monoclonal antibodies, such as long half-life and low immunogenicity. Merus' most advanced bispecific antibody candidate, MCLA-128, is being evaluated in a Phase 2 combination trial in two metastatic breast cancer populations. MCLA-128 is also being evaluated in a Phase 1/2 clinical trial in Europe in gastric, ovarian, endometrial and NSCL cancers. Merus' second most advanced bispecific antibody candidate, MCLA-117, is being developed in a Phase 1 clinical trial in patients with acute myeloid leukemia. The Company also has a pipeline of proprietary bispecific antibody candidates in preclinical development, including MCLA-158, which is designed to bind to cancer stem cells and is being developed as a potential treatment for colorectal cancer and other solid tumors, as well as MCLA-145, which is designed to bind to PD-L1 and a non-disclosed second immunomodulatory target, which is being developed in collaboration with Incyte Corporation.
Forward Looking Statement
This press release contains forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995. All statements contained in this press release that do not relate to matters of historical fact should be considered forward-looking statements, including without limitation statements regarding clinical development plans for MCLA-128, including defining a clinical plan for MCLA-128 in other solid tumors in 2018, the expected enrollment for and design of the Phase 2 clinical trial of MCLA-128, expected advancement of MCLA-158 into the clinic in 2018, the clinical development of MCLA-145, and the design and treatment potential of MCLA-128, MCLA-158 and MCLA-145.
These forward-looking statements are based on management's current expectations. These statements are neither promises nor guarantees, but involve known and unknown risks, uncertainties and other important factors that may cause our actual results, performance or achievements to be materially different from any future results, performance or achievements expressed or implied by the forward-looking statements, including, but not limited to, the following: our need for additional funding, which may not be available and which may require us to restrict our operations or require us to relinquish rights to our technologies or Biclonics® and bispecific antibody candidates; potential delays in regulatory approval, which would impact our ability to commercialize our product candidates and affect our ability to generate revenue; the lengthy and expensive process of clinical drug development, which has an uncertain outcome; the unpredictable nature of our early stage development efforts for marketable drugs; potential delays in enrollment of patients, which could affect the receipt of necessary regulatory approvals; our reliance on third parties to conduct our clinical trials and the potential for those third parties to not perform satisfactorily; we may not identify suitable Biclonics® or bispecific antibody candidates under our collaboration with Incyte or Incyte may fail to perform adequately under our collaboration; our reliance on third parties to manufacture our product candidates, which may delay, prevent or impair our development and commercialization efforts; protection of our proprietary technology; our patents may be found invalid, unenforceable, circumvented by competitors and our patent applications may be found not to comply with the rules and regulations of patentability; we may fail to prevail in existing and potential lawsuits for infringement of third-party intellectual property; and our registered or unregistered trademarks or trade names may be challenged, infringed, circumvented or declared generic or determined to be infringing on other marks.
These and other important factors discussed under the caption "Risk Factors" in our Annual Report on Form 20-F filed with the Securities and Exchange Commission, or SEC, on April 28, 2017, and our other reports filed with the SEC, could cause actual results to differ materially from those indicated by the forward-looking statements made in this press release. Any such forward-looking statements represent management's estimates as of the date of this press release. While we may elect to update such forward-looking statements at some point in the future, we disclaim any obligation to do so, even if subsequent events cause our views to change, except as required under applicable law. These forward-looking statements should not be relied upon as representing our views as of any date subsequent to the date of this press release.
Kimberly Minarovich
+1 646 368 8014
David Rosen
+1 212-600-1902
The issuer of this announcement warrants that they are solely responsible for the content, accuracy and originality of the information contained therein.
Source: Merus N.V. via Globenewswire
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BIMobject AB: Kallelse till extra bolagsstämma den 5 september 2018. Patrick Söderlund och Hjalmar Winbladh föreslås som nya styrelseledamöter i BIMobject AB. Split 2:1 föreslås.15.8.2018 15:30 | Pressmeddelande
Aktieägare representerande cirka 49 procent av rösterna i BIMobject AB har meddelat att de föreslår att Hjalmar Winbladh och Patrick Söderlund väljs till nya styrelseledamöter vid en extra bolagsstämma onsdagen den 5 september 2018. Ben O'Donnell lämnar sitt uppdrag som styrelseledamot i samband med den extra bolagsstämman. Styrelsen kommer därefter att bestå av Stefan Larsson (VD), Anders Wilhjelm (ordförande), Johannes Reischböck, Philippe Butty, Hjalmar Winbladh och Patrick Söderlund. Vidare föreslås ändrad ersättning till styrelsen. Nytt arvode utgår med 800 000 kronor, fördelat mellan styrelseordförande och Söderlund om 400 000 kronor vardera. Styrelsen föreslår även att stämman beslutar om aktieuppdelning av befintliga utestående aktier i förhållande 2:1. Patrick Söderlund, född 1973 och svensk medborgare, är Chief Design Officer samt Executive Vice President på Electronic Arts. I denna roll leder han utvecklingen av bolagets tekniska innovationer och bolagets marknadsföringsteam
BIMobject AB: Notice to attend Extraordinary General Meeting on September 5, 2018. Patrick Söderlund and Hjalmar Winbladh proposed as new Board Members in BIMobject AB. A split 2:1 is proposed.15.8.2018 15:30 | Pressmeddelande
Shareholders representing approximately 49 percent of the votes in BIMobject AB have announced that they propose that Hjalmar Winbladh and Patrick Söderlund are appointed new Board Members at an Extraordinary General Meeting to be held on Wednesday September 5, 2018. Ben O'Donnell resigns as Board Member in connection with the Extraordinary General Meeting. The Board will thereafter be composed of Stefan Larsson (CEO), Anders Wilhjelm (Chairman), Johannes Reischböck, Philippe Butty, Hjalmar Winbladh and Patrick Söderlund. Furthermore, a change in remuneration to the Board is proposed. The new Board fee totals SEK 800,000 and is to be divided between the Chairman and Söderlund with SEK 400,000 each. The board also proposes that the General Meeting resolves to split the company's shares 2:1. Patrick Söderlund, born in 1973 and a Swedish citizen, is Chief Design Officer and Executive Vice President at Electronic Arts. In his present role he manages the development of technology innovation
BIMobject AB: Offentliggörande av delårsrapport april - juni 201815.8.2018 08:00 | Pressmeddelande
Den fullständiga rapporten finns även tillgänglig på bolagets hemsida (info.bimobject.com). Andra kvartalet 2018 Faktureringen ökade med 83 procent och uppgick till 33 MSEK (18). Koncernens nettoomsättning ökade med 75 procent och uppgick till 28 MSEK (16). Fördelning mellan projekt och webservices (prenumerationer) var 40/60 procent (60/40). Bruttomarginalen ökade till 86 procent (81). Koncernens rörelseresultat förbättrades och uppgick till -15 MSEK (-17). Resultat per aktie uppgick till -0,29 SEK (-0,31) före utspädning. Kassaflödet från löpande verksamheten uppgick till -18 MSEK (-15). Ackumulerat antal användare ökade och uppgick till cirka 845 000. Ackumulerat antal nedladdningar uppgick till 25,5 miljoner. Antalet tillverkare uppgick till 1230. Styrelsen beslutade att påbörja processen för notering av bolaget vid Nasdaq Stockholm. Viktiga händelser andra kvartalet BIMobject ingår samarbete med Pipe Retail Solution för att effektivisera digital butiksplanering. BIMobject tecknar
BIMobject AB: Interim Report April - June 201815.8.2018 08:00 | Pressmeddelande
Second quarter 2018 Billing increased by 83 percent to SEK 33 (18) million. The Group's net sales increased by 75 percent to SEK 28 (16) million. The distribution between projects and web services (subscriptions) was 40/60 (60/40) percent. The gross margin increased to 86 (81) percent. The Group's operating profit improved to SEK -15 (-17) million. Basic earnings per share amounted to SEK -0.29 (-0.31). Cash flow from operating activities was SEK -18 (-15) million. The accumulated number of users increased to approximately 845,000. The accumulated number of downloads amounted to 25.5 million. The number of manufacturers was 1,230. The Board decided to initiate the process of listing the Company on Nasdaq Stockholm. Significant events during the second quarter BIMobject forms strategic partnership with Pipe Retail Solution to streamline digital planning of retail spaces. BIMobject signs Letter of Intent with leading US 3D media company Matterport. CEO's comments EQT Ventures' investment
Immunicum AB (publ) to Present Preclinical Data on Ilixadencel in Combination with CPIs and Immune Enhancers at ESMO 2018 Congress13.8.2018 08:00 | Pressmeddelande
Press Release 13 August 2018 Immunicum AB (publ) to Present Preclinical Data on Ilixadencel in Combination with CPIs and Immune Enhancers at ESMO 2018 Congress Immunicum AB (publ; IMMU.ST) announced today that the company will present a poster on its lead development candidate, ilixadencel, at the European Society for Medical Oncology (ESMO) 2018 Congress, held October 19-23, 2018 in Munich, Germany. Immunicum will announce the complete data through a press release following the presentation. The poster abstract will also be published in the ESMO 2018 Congress Abstract Book, a supplement to the official ESMO journal, Annals of Oncology. Poster Information: Title: Intratumoral administration of pro-inflammatory allogeneic, "off-the-shelf", dendritic cells in combination with anti-PD-1 or anti-CD137 has a synergistic anti-tumor effect Presentation Number: 440P Presenter: Dr. Alex Karlsson-Parra, Chief Scientific Officer Date & Time: Monday, October 22, 2018; 12.45 - 13.45 CET Location: H
Immunicum AB (publ) presenterar prekliniska data för ilixadencel i kombination med checkpointhämmare och immunaktiverare på 2018 års ESMO-kongress13.8.2018 08:00 | Pressmeddelande
Pressmeddelande 13 augusti 2018 Immunicum AB (publ) presenterar prekliniska data för ilixadencel i kombination med checkpointhämmare och immunaktiverare på 2018 års ESMO-kongress Immunicum AB (publ; IMMU.ST) tillkännagav idag att bolaget kommer att presentera en poster om sin ledande produktkandidat, ilixadencel, på 2018 års kongress för European Society for Medical Oncology (ESMO) , som hålls den 19-23 oktober 2018 i München i Tyskland. Immunicum kommer att offentliggöra fullständiga data i ett pressmeddelande som följer efter presentationen. En sammanfattning av postern kommer också att publiceras i ESMO 2018 Congress Abstract Book, ett komplement till ESMO:s officiella årsbok, Annals of Oncology. Posterinformation: Titel: Intratumoral administration of pro-inflammatory allogeneic, "off-the-shelf", dendritic cells in combination with anti-PD-1 or anti-CD137 has a synergistic anti-tumor effect (Intratumoral administration av pro-inflammatoriska allogena dendritiska celler som kan lagr
I vårt pressrum kan du läsa de senaste pressmeddelandena, få tillgång till pressmaterial och hitta kontaktinformation.Besök vårt pressrum


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On Wed, Mar 16, 2016 at 12:36 PM, Tom Lane <t...@sss.pgh.pa.us> wrote: > Robert Haas <robertmh...@gmail.com> writes: > > That doesn't update the cost of the subpath, which it probably needs to > > do. I wonder if this shouldn't be implemented by recursing. > > > if (IsA(path, GatherPath) && !has_parallel_hazard((Node *) target->exprs, > > false)) > > apply_projection_to_path(root, something, ((GatherPath *) > > path)->subpath, target); > > > Tom, any comments? I think it would be smart to push this into 9.6. > > I agree with the idea that this problem should be solved, but there's > nothing much to like about the particular details here. If we're going > to push down stuff into the workers, I think adding a Result if needed > to do that is something we'd definitely want it to do. So more > along the lines of > > if (IsA(path, GatherPath) && > !has_parallel_hazard((Node *) target->exprs, false)) > { > GatherPath *gpath = (GatherPath *) path; > > gpath->subpath = > apply_projection_to_path(root, > gpath->subpath->parent, > gpath->subpath, > target); > }
I agree. That's a cleaned-up version of the formula I posted. > However, I continue to doubt that apply_projection_to_path really ought to > know about parallel safety. > > And there is a larger problem with this: I'm not sure that it's > appropriate for apply_projection_to_path to assume that the subpath is not > shared with any other purposes. If it is shared, and we update the > subpath's target in-place, we just broke the other path chains. That's true. I don't see an obvious hazard here, because the Gather's child came from the rel's partial_pathlist, and the only way it gets used from there is to stick the Gather on top of it. So it really can't show up anywhere else. I think. But I agree it's a little scary. (To some lesser extent, apply_projection_to_path is always scary like that.) One idea is to skip generate_gather_paths() for the final rel and then make up the difference later: apply the final rel's target list once we've computed it, and then generate a gather path based on that. But I don't see an obvious way of doing that. > Now the existing uses of apply_projection_to_path don't have to worry > about that because they're always messing with paths whose parent rel > isn't going to be used in any other way. Maybe this one doesn't either > because the subpath would always be a partial path that won't have any > other potential application besides being a child of *this specific* > Gather path. But I'd like to see that addressed in a comment, if so. > > If it's not so, maybe the answer is to always interpose a Result node, > in which case just use create_projection_path() in the above fragment. Mmmph. That seems like a 2-bit solution, but I guess it would work. What if we taught create_projection_plan() to elide the Result node in that case? That is, instead of this: if (tlist_same_exprs(tlist, subplan->targetlist)) We could do this: if (is_projection_capable_path(subplan) || tlist_same_exprs(tlist, subplan->targetlist)) -- Robert Haas EnterpriseDB: http://www.enterprisedb.com The Enterprise PostgreSQL Company -- Sent via pgsql-hackers mailing list (email@example.com) To make changes to your subscription: http://www.postgresql.org/mailpref/pgsql-hackers


text: foodandwine.comNo One Is Using Napkins AnymoreAccording to a recent survey, napkins are becoming obsolete. Marketing intelligence agency Mintel conducted a study in which only 56 percent of participating consumers reported purchasing paper napkins in the past six months—but 86 percent bought paper towels. Apparently, people are using paper towels as napkins.


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WoW page on Battle.net launcher is blankMac Technical Support
Since last night, same problem here. Only way I can launch the game is by the Apps folder on my Mac.
WoW Performance Guide For Macs - Patch 7.3Mac Technical Support
Thanks, Stoneblade. As you work at it, can you see if there is a fix for the massive stutter I (and I think quite a few others) get every time I go to a new location? It is so bad it makes the game unplayable --I get like 1.5 seconds play, then freeze for .5 sec, over and over again. Not just movement, but also shooting and everything -- screen just freezes completely for the .5 second.Doubt if it is my gear, it is a new iMac Pro with 3GHz Intel Xeon, 128GB memory, Radeon Pro Vega 64. 27" retina display and a second 27" LG UltraFine display.I have tried almost every level of graphics settings …
Mac FPS drop since patch - fixed!Mac Technical Support
Bindley, thanks for the excellent post on workaround settings. After 3 days of total frustration, I tried them, and at least so far they seem like it makes the game playable. Damn shame, though, that I have an excellent and updated system, including a new LG 5k ultra fine monitor, and the only way to play is to make the thing look like a 10-year old monitor. :-(Edited -- nope, sorry, none of them worked. When I logged back in, the problems were back.
Stuttering, FPS drops after 8.0General Discussion
Massive stuttering randomly, but frequent enough to make the game unreliable at best and unplayable at worst. I have a new system, new monitor, everything far exceeds Blizz's new equipment requirements. I have tried every suggestion in the forums for tweaking video settings, including advanced ones, but nothing helps. I cannot even run world quests because I never know when the massive stuttering will kick in.This is one of those too-frequent times when the hardware people and the internet providers blame the app, and the app blames the hw and internet providers. all I know is, it worked fine …
Choppy gameplay with 60fps?Mac Technical Support
07/30/2018 03:12 AMPosted by Nausic0F286B2013..?? do u even know we are almost in 2019.. i bet if u would buy a new imac pro everything would work without problem.Nope, I have a brand new iMac Pro and the game stutters so bad now it is unplayable. OS is completely up to date, and the graphics card — while admittedly is not one serious gamers would brag about — is the high end Radeon Pro Vega 64. All of this should be way more than sufficient to run this game. It worked fine before 8.0.
Choppy gameplay with 60fps?Mac Technical Support
I am having the same problem with my new LG Ultrafine 5k monitor that I use with my iMac pro. I am running updated OS, have 128 GB of memory, and Radeon Pro Vega 64 16368 MB. Have tried all sorts of system graphics settings in game, but it is herky-jerky almost to unplayable level. I get 60fps for 1-2 seconds, then a second of almost standstill, looks like 20-30 fps, then back to 60, etc. Makes no difference with vsync setting, or with full windowed or not.It does seem to finally have gone away while I am in Dal, so maybe the shaders thing is happening, but honestly if I have to re-cover every…
Why cant we get online?Technical Support
If they are having problems now, I can hardly wait until they try to roll out the new expansion simultaneously throughout the world...
Live Developer Q&A Thursday 6/14 – Submit Your QuestionsGeneral Discussion
Why not turn the gardener's cottage in our garrisons over to each of us as player housing? It's already there, and you could add in couple quests for decorating. Voila! Almost no work on your part, lots of happy players, everybody wins.
Live Developer Q&A Thursday 6/14 – Submit Your QuestionsGeneral Discussion
When will we get much-needed changes to skinning? Things like ability to skin if people refuse to loot, group-skinning like we have now for mining and herbalism, and AoE skinning? Come on, it's past time!


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Examples of navigator in a Sentence
The crew includes a copilot and a navigator.
Would you be willing to act as navigator while I drive?
The ship is equipped with a satellite navigator.
Recent Examples of navigator from the Web
Not always the most graceful navigator of his own fame, Smith, 26, also seems to have grown into himself as a person, performer and advocate — an air of self-assurance that informed every second of his Wednesday show.
Eight members of the team are back for this race, with some playing leading roles: Liz Wardley, a watch captain under Caffari; Abby Ehler, a boat captain on Team Brunel; and Libby Greenhalgh, the navigator on Team Sun Hung Kai/Scallywag.
Behavioral health navigators could help cut down that time, Kromm said, by working more with families to figure out their next treatment steps outside the emergency room.
Another change involves the housing navigators, who help connect the homeless to various resources.
The trafficking group allegedly organized transport from the Tunisian port of Nabeul to Trapani in Sicily aboard rubber dinghies equipped with high-speed outboard motors and trained navigators for 3,000 euros ($3,690) to 5,000 euros per person.
In a sharp shift, the new rules further weaken the network of consumer assisters, known as navigators, whose funding the Department Health and Human Services slashed last year.
In a sharp shift, the new rules further weaken the network of consumer assisters, known as navigators, whose funding the Department Health and Human Services slashed last year.
But navigators say this understates their accomplishments.
These example sentences are selected automatically from various online news sources to reflect current usage of the word 'navigator.' Views expressed in the examples do not represent the opinion of Merriam-Webster or its editors. Send us feedback.
First Known Use of navigator
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NAVIGATOR Defined for English Language Learners
Definition of navigator for English Language Learners
: a person who finds out how to get to a place : a person who navigates a ship, an airplane, etc.
: a device (such as a computer) that is used to plan or find the route to a place
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Aceline Lamare Storm Door May 24th, 2018
There are many different types of doors that range from metal steel aluminum wooden or even fiberglass that not only prevents moisture and bugs but also gives some homes a different look. In some cases the storm door may not...Read More
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Hinges knobs and closure devices which are not as effective as they where when new can easily be replaced to restore the door to like new condition. The little clips that serve to hold the glass in place for the...Read More
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This lets air into the home and circulate throughout it. During the warm summer months this can cool down the house just as well as an air conditioning unit. Storm doors also brighten up the interior of the house. By...Read More
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It is advisable to be familiar with any precaution aspects that may be mentioned. Instruction sheets may be in English and Spanish. Ensure that the tools necessary for the completion of the project are at hand. Some tools that you...Read More
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Storm doors also help to protect homeowners and their homes from the harmful outside elements and weather. Air and light are able to come in through the screen and glass panels however rain hail bugs and other potential threats are...Read More
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Now that you have accurate measurements for the storm doors youll need to shield your exterior wood doors and enhance your homes security you can give them to your general contractor take them to a home improvement store or give...Read More
Aceline Lamare Storm Door March 06th, 2018
This keeps unwanted people from coming inside the home. People who have already installed them on their homes enjoy having them because of the additional level of security they provide. They act as a barrier between the homeowner and any...Read More
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By Catherine R. Sands on June 13 2018 15:29:55
A business plan is not a document you create once and store in your bottom drawer. It is a living guide that you should develop as your business grows and changes. Successful businesses review and update their business plan when circumstances change.
A business plan is a blueprint for how your business will run and reveals what future direction your business will take. Understandably you will want to be careful who you show your plan to and avoid your competition seeing it.
Make it clear and concise; include only the most important elements, keeping it at a maximum of half a page. To create the summary go back over your plan, pick three or four key messages and write a brief overview, then conclude with details of the action you want the reader to take.
You may want to consider the following key questions to help determine if you are ready to start writing your business plan.
~ Have you thoroughly refined your business idea so you have a good understanding of how your business will operate?
~ Have you researched your business concept to determine if there is a need for it in the marketplace?
~ Have you completed a feasibility study to determine expected level of success?
~ Do you have the money required to start and grow the business?
~ Are you prepared to invest significant time into the business to get it up and running?
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For Cornell Evans, supervisor of the exhibit shop for the Smithsonian Institution's Freer Gallery of Art, the motto is: "Anything made of wood, we can make."
The "we" consists of fellow woodcraftsmen John Marshall and Francis Smith, and finisher John Bradley.
Since last fall, the four men have worked on the display areas of the Arthur M. Sackler Gallery. They have constructed a large moongate entryway, 10-foot-long lattice panels, ornate brackets, display cases, window frames, floor moldings, and two 8-by-5-foot lattice doors.
Scheduled to open Sept. 28, the Sackler gallery will showcase Asian and Near Eastern art including ancient jades, ivories, ceramics and paintings -- part of a $7.3 million museum, research and educational complex on the Mall.
(Because of space considerations, most of the Sackler complex has been built underground.)
The display areas for these artifacts were designed by the Sackler's assistant head of design, John Zelinik, who along with department head Patrick Sears spent months researching Chinese and Near Eastern architecture. Despite the often elaborate plans, Zelinik and Sears had no worries about the Freer woodcraftsmen being up to the task.
"We didn't even ask any questions about whether they could do it. We knew they could do it," Zelinik said.
"We looked upon it as a challenge," Evans said.
For the lattice panels, Evans and his crew took 6-inch-by-14-foot boards of poplar and cut them into 10- and 12-foot strips called "runs." These runs were then planed down to three-quarter by seven-eighth-inch pieces that were glued together to make the lattice pattern.
A 10-foot panel requires 1,000 such pieces, and all of them have to be planed to the exact measurements specified in the blueprints. An error in even one piece will create a flaw in the overall scale of the panel.
It's the sort of precision demand that the Freer craftsmen are used to. "You have to be right on it," said Marshall, a 20-year veteran of woodcrafting who made the doors to the Freer's souvenir shop. "Even with things like floor moldings; you want those moldings to look like they grew around that wall."
In most cases, a designer turns over blueprints to a woodcrafter. After studying the blueprints for a while, the woodcrafter draws the design onto the wood, enlarging it to the proper scale. This drawing is called a layout and is often done with nothing more than a pencil and a straight edge. For designs that require curves, the craftsmen use trammel points, two clamps with attached pencils that can be fitted to either end of a narrow length of wood. The craftsman centers with one marker and draws the circular line with the other in much the same way a geometry student uses a drawing compass.
Sometimes, the craftsmen have to work without blueprints. Evans was once asked to build two replicas of a lattice-back, Ming Dynasty bench. The designers had no blueprints, just a book photograph. In addition, they wanted him to "westernize" the benches by making the seats shorter and the legs longer. With only the photo to go on, Evans built the two benches that can be seen in the downstairs hallway of the Freer Gallery.
A craftsman for 23 years who is also an assistant football coach at Ballou High School, Evans first became interested in woodworking while growing up in the Manor Park area. He built soap box cars for himself and his friends, and they staged races on Peabody Street.
Evans enrolled at Bell Vocational High School, where he studied in the wood shop. By his senior year, he was in a job training program at Garrett Plastics and Store Fixtures. "Mr. Garrett was a big influence on me," Evans said. "He was the first black man I'd ever seen who had his own mill. He was a sharp woodworker and he encouraged me."
After high school, Evans did four years of apprenticeship under German woodcraftsman Wilhelm Linden.
"He was precise," Evans said of Linden. "He stayed on my back. He taught me about taking an image of a drawing off the paper and putting in my mind."
Seeing-in-the-mind and patience are two skills Evans considers essential to his work: "When you get the blueprint, you have to be able to see what it {the design} is going to look like when it's done, like a camera . . . . And you have to be patient, otherwise you'll get frustrated because a good woodcrafting job takes time."
When the woodcraftsmen are done, they turn the work over to John Bradley.
"What I know you can't get from a book," said Bradley, who has been a finisher for 18 years. "What I know comes from experience."
Bradley mixes and experiments with lacquers to come up with the best stains for each project he is given. "Oftentimes a manufacturer will state in the directions that a stain or lacquer won't do certain things, but I can work with it in the shop and get more out of it. There's a lot of creativity involved."
The woodcrafters feel the same way about their work.
"You have to use your mind as well as your hands," said Smith, a woodcraftsman for 16 years, the last four at the Freer, "and the work is difficult because you have your different cuts and measurements."
"You have to put yourself into it," Evans said. "This work is my love. We're artists."


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Mission Areas
Water Resources
Mission Areas L2 Landing Page Tabs
Water is one of seven science mission areas of the U.S. Geological Survey (USGS). Water's mission is to collect and disseminate reliable, impartial, and timely information that is needed to understand the Nation's water resources.Read Science Plan
Oregon Water Use Program
With the ever-increasing rate of utilization of and competition for water (particularly during periods of drought) accurate, current water-use information is of considerable value. This is particularly so in determining future water availability in hydrologically critical areas and for making sound resource-management decisions. For the Oregon Water Science Center, a viable water-use data-...
SPARROW Model Assessments of Nutrients and Suspended Sediment in the Pacific Northwest and California
SPARROW can be used to relate water-quality data to landscape characteristics, such as natural properties and human activities
Malheur Lake Light Transmission Study
The Malheur National Wildlife Refuge provides habitat for a variety of highly valued ecosystem services, including shorebirds, waterfowl, and a diversity of other wildlife species.
Future Climate Effects on Columbia and Willamette River Levees
USGS research directly helps local public agencies that are responsible for the design and maintenance of the levees that surround the northern Portland metropolitan area with the goal of protecting life and property in the event of flooding from the Columbia and Willamette Rivers that surround the city.
Upper Klamath River Basin Forecasts
"Determining water availability in the Upper Klamath Basin has always had a degree of uncertainty as a result of the complex hydrology and geology in the region and limited streamflow data."
Spring Vulnerability Study for Southeastern Oregon
Evaluating Spring Vulnerability to Climate Change on BLM Priority Management Areas in Southeastern Oregon
Harney Basin Groundwater Study
This study will characterize and quantify the groundwater system in the Harney Basin to address gaps in our present understanding.
Willamette River Basin Dissolved Gas Monitoring Network
USGS total dissolved gas (TDG) data help guide spill and discharge management from dams operated along tributaries of the Willamette River.
Sediment Fingerprinting in the Upper Klamath Basin
Sediment fingerprinting has been used successfully to identify land uses that are the major sources of sediment. This study will apply these techniques in a predominantly rural, volcanic landscape.
Effects of Highway Runoff on Water Quality
"SELDM facilitates analysis by providing precipitation, pre-storm streamflow, and other variables by region or from hydrologically similar sites."
Macroinvertebrate Communities Evaluated Before and After a Channel Restoration Project in Silver Creek, Blaine County
The U.S. Geological Survey, in cooperation with Blaine County and The Nature Conservancy, evaluated the status of macroinvertebrate1 communities prior to and following a channel restoration project in Silver Creek, Blaine County, Idaho. The objective of the evaluation was to determine whether 2014 remediation efforts to restore natural channel conditions in an impounded area of Silver Creek...
Water Quality in Aquifers Used for Drinking-Water Supplies, Gem County
The U.S. Geological Survey, in cooperation with Gem County and the Idaho Department of Environmental Quality, is assessing the quality of groundwater from freshwater aquifers used for drinking-water supplies.
The USGS collects, analyzes, and distributes data on a wide variety of water-related issues and resources. Much of our data is publicly available through the National Water Information System (NWIS), but additional datasets and analytical tools are also available.Access NWISWeb
Computed instantaneous suspended-sediment concentration in Williamson River
Suspended-sediment concentration data from National Real-Time Water Quality (NRTWQ) website.
Tualatin River Basin Water-Quality Sites
Map of currently active monitors in the Tualatin River Basin, Oregon.
Tualatin River Basin Water-Quality Samples
Real-time compilation of water quality samples for Tualatin River Basin from USGS National Water Information System (NWIS).
Harney Basin Data Mapper
Map viewer of groundwater sites in the Harney Basin, Oregon
Oregon Streamflow Table
Table of current streamflow conditions for 245 site(s) in Oregon.
Flood Inundation Mapper
The USGS Flood Inundation Mapping Program has two main functions: 1) partner with local communities to assist with the development and validation of flood inundation map libraries; and 2) provide online access to flood inundation maps along with real-time streamflow data, flood forecasts, and potential loss estimates.
Portland HYDRA Rainfall Network
The HYDRA rainfall network is operated and maintained by the City of Portland Bureau of Environmental Services. Rainfall data are provided with their permission and cooperation.
National Water Information System (NWIS) - Oregon
National Water Information System: Mapper (Oregon)
Dissolved Organic Matter in the Upper Klamath River, Lost River, and Klamath Straits Drain
Data from an Analysis of Dissolved Organic Matter in the Upper Klamath River, Lost River, and Klamath Straits Drain, Oregon and California, 2013–16
Goldman, J.H., 2017, Data from an analysis of dissolved organic matter in the Upper Klamath River, Lost River, and Klamath Straits Drain, Oregon and California, 2013–16: U.S. Geological Survey data release,...
Virginia Water-Monitoring-Site Mapper
The Water-Monitoring-Sites Mapper is an interactive map of Virginia water monitoring-site locations from the USGS National Water Information System (NWIS). It provides access to surface water, groundwater, and water quality monitoring data for active sites. The functionality includes query, select, tabular display by county,...
West Virginia Water-Monitoring-Site Mapper
The Water-Monitoring-Sites Mapper is an interactive map of West Virginia water monitoring-site locations from the USGS National Water Information System (NWIS). It provides access to surface water, groundwater, and water quality monitoring data for active sites. The functionality includes query, select, tabular display by county,...
West Virginia Real-Time Precipitation Network
This interactive map shows current and cumulative rainfall total for precipitation sites in West Virginia. Map provides real-time precipitation radar image to overlay from National Weather Service.
Downloadable spatial data files for exploration and analysis.
Alabama Climate Response Network
Network wells depicted on the Climate Response Network location map
Note: Color shading in the table below indicates multiple wells that plot as a single point on the state location map above.
Note: BLS = Water Level in Feet Below Land Surface, RVD = Water Level referenced to a vertical datum
Alabama Active Water Level Network
Alabama Counties depicted on the state location map with active wells
Mobile River Basin Study
The Mobile River Basin in Alabama, Georgia, Mississippi, and Tennessee is one of the 59 study units that are part of the U.S. Geological Survey's National Water-Quality Assessment (NAWQA) Program.
Michigan Lake Water Clarity Interactive Map Viewer
Available online are estimated Secchi-disk transparency (eSDT) and corresponding estimated trophic state index (eTSI) values for Michigan inland lakes. To view available eSDT for Michigan inland lakes greater than 20 acres without interference from clouds, cloud shadows, dense vegetation or shoreline, go to the Michigan Lake Water Clarity Interactive Map Viewer.
Buffalo National River Services and River Level Guide
Real-time displays of current floating conditions at various sites along the Arkansas Buffalo River.
How much water do we use?
Map viewer used to visualize water use by region and date for U.S. freshwater withdrawals, 1950-present (created by USGS VIZLAB)
Major rivers and tributaries in Alabama (taken from Hutson and others, 2009)
As part of their mission to protect public health and aquatic ecosystems, Alabama state agencies need accurate and representative streamflow statistics to establish realistic and applicable criteria for both water quality and water quantity (fig. 1).
Arkansas Groundwater - Quality Network
The Arkansas Groundwater - Quality Network is a web map interface that provides rapid access to the U.S. Geological Survey's (USGS) NWIS and the U.S. Environmental Protection Agency's (EPA) STORET databases of ambient groundwater information. The interface enables users to perform simple graphical analysis and download selected water-quality data.
StreamStats Alabama
Beta version 4 is now available for most states on a trial basis, and version 3 remains available. Beta version 4 provides a single user interface (at http://streamstatsags.cr.usgs.gov/streamstats/) for all states that are implemented, rather than separate applications for each state, as in versions 2 and 3, and the user interface is more user friendly than previous versions.
Largest local sources of total nitrogen for National Hydrography Dataset catchments in the United States Pacific Northwest (2002 conditions)
USGS StreamStats
StreamStats is a Web-based tool that provides streamflow statistics, drainage-basin characteristics, and other information for USGS streamgaging stations and for user-selected ungaged sites on streams. When users select the location of a streamgaging station, StreamStats provides previously published information from a database. When users select a site on an ungaged stream,
U.S. Geological Survey Flood Inundation Mapping Science
Static flood-inundation map libraries consist of maps that have been created in advance of a flood that are ready to be served through the Internet. Each library consists of a set of flood extent and depth maps developed for predetermined stream stage intervals (for example, a map for each one foot of stage).
Linking transit times to catchment sensitivity to atmospheric deposition of acidity and nitrogen in mountains of the western United States
Transit times are hypothesized to influence catchment sensitivity to atmospheric deposition of acidity and nitrogen (N) because they help determine the amount of time available for infiltrating precipitation to interact with catchment soil and biota. Transit time metrics, including fraction of young water (Fyw) and mean transit time (MTT), were...Clow, David W.; Mast, M. Alisa; Sickman, James O.
Detections of current-use pesticides at 12 surface water sites in California during a 2-year period beginning in 2015
Surface water samples were collected by the U.S. Geological Survey and multiple cooperators during base flow/irrigation runoff and storm runoff conditions from 12 sites throughout California, over 2 consecutive years beginning in April 2015, from both urban and agriculturally dominated watersheds. Water samples were analyzed by gas chromatography/...Sanders, Corey J.; Orlando, James L. ; Hladik, Michelle L.
Rating stability, and frequency and magnitude of shifts, for streamgages in Virginia through water year 2013
The U.S. Geological Survey, in cooperation with the Virginia Department of Environmental Quality, has quantified several measures of rating stability and the frequency and magnitude of changes to ratings through time for 174 real-time continuous streamgages active in Virginia as of September 30, 2013. Generalized additive models (GAMs) were fitted...Messinger, Terence; Burgholzer, Robert W.
Spatial and temporal trends in selenium in the upper Blackfoot River watershed, southeastern Idaho, 2001–16
Phosphate mining in southeastern Idaho has been an important economic driver for the region and State for over 100 years, but weathering of mining waste rock has also released selenium into the Blackfoot River. This report analyzes and presents data from three separate but complementary studies monitoring selenium in streams in the region. The U.S...Zinsser, Lauren M.; Mebane, Christopher A.; Mladenka, Greg C.; Van Every, Lynn R.; Williams, Marshall L.
Comparison of regression relations of bankfull discharge and channel geometry for the glaciated and nonglaciated settings of Pennsylvania and southern New York
Streambank erosion in areas of past glacial deposition has been shown to be a dominant source of sediment to streams. Water resource managers are faced with the challenge of developing long and short term (emergency) stream restoration efforts that rely on the most suitable channel geometry for project design. A geomorphic dataset of new (2016, n=...Clune, John W.; Chaplin, Jeffrey J.; White, Kirk E.
Groundwater discharge characteristics for selected streams within the Loup River Basin, Nebraska, 2014–16
Streams in the Loup River Basin are sensitive to groundwater withdrawals because of the close hydrologic connection between groundwater and surface water. Groundwater discharge is the primary component of streamflow in the Loup River Basin and constitutes more than 90 percent of streamflow in the central part of the Sand Hills. To improve the...Hobza, Christopher M.; Schepers, Aaron R.
Preliminary groundwater salinity mapping near selected oil fields using historical water-sample data, central and southern California
The distribution of groundwater salinity was mapped for 31 oil fields and adjacent aquifers and summarized by 8 subregions across major oil-producing areas of central and southern California. The objectives of this study were to describe the distribution of groundwater near oil fields having total dissolved solids less than 10,000 milligrams per...Metzger, Loren F.; Landon, Matthew K.
Refinement of a regression-based method for prediction of flow-duration curves of daily streamflow in the conterminous United States
Regional regression is a common tool used to estimate daily flow-duration curves (FDCs) at ungaged locations. In this report, several refinements to a particular implementation of the regional regression method for estimating FDCs are evaluated by consideration of different methodological options through a leave-one-out cross-validation procedure...Over, Thomas M.; Farmer, William H.; Russell, Amy M.
Coeur d'Alene Basin Environmental Monitoring Program, surface water, northern Idaho—Annual data summary, water year 2017
Streams within the Coeur d'Alene River drainage basin in northern Idaho have been extensively affected by historical mining activities and are subject to ongoing remedial actions as part of the Bunker Hill Mining & Metallurgical Complex Superfund Site. The U.S. Geological Survey (USGS) operates 12 real-time streamgages and collects surface-...Zinsser, Lauren M.
Prioritization of oil and gas fields for regional groundwater monitoring based on a preliminary assessment of petroleum resource development and proximity to California's groundwater resources
The California State Water Resources Control Board initiated a regional monitoring program in July 2015 to determine where and to what degree groundwater quality may be adversely impacted by oil and gas development activities. A key issue in the implementation of the regional groundwater monitoring program is that each year, detailed...Davis, Tracy; Landon, Matthew K.; Bennett, George L.
Geohydrology, geochemistry, and numerical simulation of groundwater flow and land subsidence in the Bicycle Basin, Fort Irwin National Training Center, California
Groundwater pumping from Bicycle Groundwater Basin (referred to as Bicycle Basin) in the Fort Irwin National Training Center, California, began in 1967. From 1967 to December 2010, about 46,000 acre-feet of water had been pumped from the basin and transported to the Irwin Basin. During this time, not only did water levels in the basin decline by...Densmore, Jill N.; Woolfenden, Linda R.; Rewis, Diane L.; Martin, Peter M.; Sneed, Michelle; Ellett, Kevin M.; Solt, Michael; Miller, David M.
Modeling managed flows in the Sacramento/San Joaquin watershed, California, under scenarios of future change for CASCaDE2
Projections of managed flows from the Sacramento River/San Joaquin River watershed, California, into the San Francisco Bay and Sacramento-San Joaquin Delta under scenarios of future climate change are needed for evaluations of potential impacts on water supply and estuarine ecosystems. A new, multiple-model approach for achieving this is described...Knowles, Noah; Cronkite-Ratcliff, Collin
Software and related material (data and documentation) are made available by the USGS to be used in the public interest and the advancement of science.
Exploration and Graphics for RivEr Trends (EGRET)
Exploration and Graphics for RivEr Trends (EGRET) is an R-package for the analysis of long-term changes in water quality and streamflow, including the water-quality method Weighted Regressions on Time, Discharge, and Season (WRTDS).
Water Resources Applications Software
Software and related material (data and documentation) are made available by the U.S. Geological Survey (USGS) to be used in the public interest and the advancement of science.
Shoreline Management Tool
The Shoreline Management Tool—An ArcMap Tool for Analyzing Water Depth, Inundated Area, Volume, and Selected Habitats, with an Example for the Lower Wood River Valley, Oregon
Calculate Streamflow Depletion by Nearby Pumping Well - STRMDEPL08
STRMDEPL08—An Extended Version of STRMDEPL with Additional Analytical Solutions to Calculate Streamflow Depletion by Nearby Pumping Well
The USGS produces many types of multimedia products. Use the links below to browse our offerings of photograph galleries, podcasts and sound files, videos, aerial photos, and posters related to water. The USGS Newsroom has a Web page that highlights the main collection of multimedia products.
USGS scientists on the Colorado River in the Grand Canyon, AZ
USGS scientists on the Colorado River in the Grand Canyon, AZ
Grand Canyon bank Erosion.
Comparing 2009 vs 2014 Bank surface after erosion, Grand Canyon AZ.
Sediment Deposit in the Grand Canyon, AZ
Sediment Deposit in the Grand Canyon, AZ
Assateague Island Gage
Assateague Island Gage
Understanding Floods | Long-term Streamflow Data Collection (AD)
The USGS is developing methods to improve data collection during floods to gain new insight into the rise and fall of flood waters. In the past, the only data left behind after a flood was how high the water got, or the peak of the flood. This video presents the methodology that hydrologists are using to set up a Continuous Slope-area Reach in remote areas that are...
Understanding Floods | Long-term Streamflow Data Collection
The USGS is developing methods to improve data collection during floods to gain new insight into the rise and fall of flood waters. In the past, the only data left behind after a flood was how high the water got, or the peak of the flood. This video presents the methodology that hydrologists are using to set up a Continuous Slope-area Reach in remote areas that are...
Arial Image of the 2011 Missouri River Flood
Arial Image of the 2011 Missouri River Flood
Water Sampling on the Floodplain of the Missouri River
Water Sampling on the Floodplain of the Missouri River
Arial Image of the Deposits of the 2011 Missouri River Flood
Arial Image of the Effects of the 2011 Missouri River Flood
Map of the U.S. by state, showing total water withdrawals, 2015
Map of the U.S. by state, showing total water withdrawals, 2015
Indirect Measurement Field Notes and Metadata
This video describes the notes and other metadata that need to be recorded during indirect measurement surveys.
June 2018 "People" category winner Molly Schreiner
Molly Schreiner water quality sampling at Bound Brook in Middlesex, NJ
Not All Arsenic Tests are Created Equal
The reliability of arsenic testing for drinking water in Minnesota depends on how and when well water samples are collected, according to a new U.S. Geological Survey and the Minnesota Department of Health study, which highlights ways to improve the accuracy of arsenic tests for private wells.
Water-Quality Monitoring Program Aids Restoration of Great Lakes
A new water-quality monitoring program, established by the U.S. Geological Survey, can provide scientists and managers with the best available data to help evaluate the health of Great Lakes ecosystems and improve water quality for recreation and commercial fishing.
January 23, 2018 M7.9 Gulf of Alaska Earthquake and Tsunami
One week ago, on January 23rd at 12:31 a.m. local time, Alaskans were rocked by a magnitude 7.9 earthquake, with an epicenter in the Gulf of Alaska, about 350 miles southwest of Anchorage, and about 175 miles southeast of Kodiak Island.
Salinity Decreased throughout Upper Colorado River Basin Over Time
Salinity loads that originate from groundwater within the Upper Colorado River Basin have decreased from 1986-2011, according to a new U.S. Geological Survey study done in cooperation with the Colorado River Basin Salinity Control Program.
Alaska Earthquake Rattles Florida's Groundwater Plumbing
At 12:32 am Alaska time on January 23, 2018, a magnitude 7.9 earthquake shook Alaska residents out of their beds and set off fears of a tsunami all down the West Coast. Fortunately, the tsunami was only a few inches in height, but within an hour of the earthquake in Alaska, waves of a different sort were hitting far away in Florida.
USGS gages assist Georgia, Alabama and Florida water management efforts
Fayette County Georgia, Water System Director, Lee Pope, discusses water management efforts to alleviate issues downstream.
Groundwater Quality in the North: The Glacial Aquifer System
A regional assessment of untreated groundwater in the Glacial aquifer system, which includes parts of 25 states across the northern contiguous United States, is now available from the U.S. Geological Survey.
Groundwater Quality in the Southwest: The Rio Grande Aquifer System
A regional assessment of untreated groundwater in the Rio Grande aquifer system, which includes parts of Colorado, New Mexico and Texas, is now available from the U.S. Geological Survey.
Groundwater Quality in the East: The Piedmont and Blue Ridge Crystalline-Rock Aquifers
A regional assessment of untreated groundwater in the Piedmont and Blue Ridge crystalline-rock aquifers, which includes parts of 11 states across the contiguous United States, is now available from the U.S. Geological Survey.
The Quality of the Nation's Groundwater: Progress on a National Survey
This story was updated on December 7, 2017.
The U.S. Geological Survey is near the midpoint of a complex undertaking to survey the quality of the nation's largest drinking-water resource.
Groundwater Quality in the Midwest: The Cambrian-Ordovician Aquifer System
A regional assessment of untreated groundwater in the Cambrian-Ordovician aquifer system, which includes parts of Minnesota, Wisconsin, Michigan, Iowa, Illinois, Missouri and Indiana, is now available from the U.S. Geological Survey.
Scientists Home in on Causes of High Radium Levels in Key Midwestern Aquifer
Oxygen levels, dissolved minerals among factors responsible for high concentrations of radium in untreated water from aquifer that underlies six states


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Pomegranate - Mason Jar Candle
Regular price $16.95
An exotic and sweet scent that is refreshing and slightly floral.
All of our candles are made with 100% soy wax.
Burn Time = 90-100 Hours (16oz Mason Jar)
Approx 5.1" Tall and 3" Diameter
Add a prize to your candle! What will you get? Cash? a gift? a reward? Jewelry? Order and find out!


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New homes in Cape Coral Florida have been popping up post recession in strong numbers. Waterfront homes were the first to return as builders looked to take advantage of Cape Corals biggest asset. Waterfront new homes in Cape Coral pricing tends to run north of 400k. This put a large section of buyers on the sidelines for a long period of time. Next came the production builders. Pricing was better, but options were very limited and quality was suspect. Now, Irma comes to visit and more questions about new homes in Cape Coral are being raised. Are the current homes being built safe? Will they withstand a major storm? Are they efficient? Well, homes have to be to the current code but not beyond. One builder of new homes in Cape Coral is going above and beyond Cape Signature Homes is using a revolutionary wall system called Hercuwall.
Watch the video below from the nations third largest home builder currently using Hercuwall.
HercuWall® is a single product that combines many operations: composite concrete and steel structure, superior insulation, water and vapor barrier, window and door casings and sills, and attachment points for drywall and exterior finishes.
HercuWall® incorporates patented ShearStrip® Technology that is a disruptive innovation facilitating concrete construction without conventional steel rebar reinforcing. This advancement is the "secret sauce" that gives HercuWall® its unique advantage in the marketplace.
HercuWall® consists of a kit of panels manufactured on computer controlled equipment to exactly match the architectural plans for each individual project. HercuWall® is delivered to the job site as a kit of panels that when set in place exactly match the plans for the building. The kit contains corner panels, wall panels, and window and door panels. Installed by framers or block masons, the system is easy to learn and requires no special trades skills as no job site modification of the panels is required.
HercuWall® competes with wood frame and concrete block construction providing a faster build cycle, a stronger, more energy efficient, bug proof, water proof, mold proof, quieter home or building. Highly durable and virtually maintenance free.
HercuWall® window and door openings more precise than site built construction. Each opening is cased out with a extruded XPVC material that looks and feels like wood but is impervious to water and weather, will never rot, and is maintenance free. The XPVC casings can be painted and exposed or wrapped with stucco or siding on the exterior and drywall on the interior. A sloped window sill from the same materials finishes the opening.
As you can see the home below appears as any other home when finished.
Backed by over 40 years experience in construction, Cape Signature Homes has devised 8 floor plans for building new homes in Cape Coral with standard features that are considered upgrades with many other builders. These features include a metal roof with 40 year warranty, brick walkways and driveway, choice of exterior finish, granite counters, many flooring options, 9′ ceilings with inset trays, choice of appliance package and much more.
Located in and specializing in new homes in Cape Coral, the team has been serving the West Coast of Florida from Tampa to Naples since 2002. Specializing in helping our clients design and build high-end, custom new homes in Cape Coral constructed using a revolutionary and state-of-the-art insulated, poured concrete paneling system that delivers superior strength, safety, and energy efficiency.
We currently feature 8 floor plans ranging in size from 1325 sf. to 2338 sf. and prices starting at $180,000. The models for the new homes in Cape Coral include The SeaGem, The GulfView, The SandDollar, The BeachWalk, The SandCastle, The Coconut Cove, The Surfside and The Boca Grande.


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Thinking About a Home Remodel? Read Our Home Remodeling Tips!
Considering a home remodeling project for your Chicagoland home? Renovation projects are a great way increasing the value of your investment and tailor your space to your lifestyle at the same time.
In this post, we've compiled some tips for those considering a home remodeling project. Questions about any of our tips? Let us know by contacting us!


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Local musicians are preparing to put on a show in Maine to help raise money for striking FairPoint workers.
The concert on Monday evening at the Empire in Portland is being headlined by eight-piece band Model Airplane.
Other performers include Adam Waxman, Joe Farrell and Kenya Hall.
About 1,700 FairPoint workers represented by two unions in Maine, Vermont and New Hampshire have been on strike since Oct. 17.
Union officials say they have received nearly $150,000 in donations to help support the workers who are no longer earning their paychecks. People have also sent food, medicine, grocery store gift cards and other gifts.
Monday's concert begins at 9 p.m. and tickets are $10.
Cops & Courts
71-year-old Camden driver leads police on multi-county chase
How do the forecasts stack up?
Green Plate Special
Recipe: Roasted Tomato, Fennel and Sardine Pasta
Former Maine drug agent steps into an unlikely role
Cops & Courts
Maine judge tells no-show jurors they're out of order


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Stihi u konveyera (Poems at conveyer belt).
by Bezymenski, Alexander
OGIS, 1932. Paperback. Very Good+. 16mo. Original printed wraps. (Inventory #: KC16109)
by Regional Plan Association; Okamoto, Rai Y.; Williams, Frank E.; et alNew York : Viking Press , 1969
by [newspaper]New York : Samuel Loudon , 1789
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