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I kinda hate this character buy at the same time i find him very interesting.
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Check out the full color version here http://bencamberos.com/
The 10 Most-Viewed Pieces Of Youtube Animation Aren't What You Might Expect - Youtube is the new gatekeeper for animation creators – and that's not necessarily a good thing. The post The 10 Most-Viewed Pieces Of Youtube Animation A...
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Aug 17 | 6 Elul |
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TIGIT, also known as WUCAM and Vstm3, is an immune checkpoint protein expressed on lymphocytes. Highest expression levels are observed on effector CD4+ and CD8+ T cells, regulatory T cells, and NK cells. TIGIT has several distinct mechanisms of action that inhibit lymphocyte activation. First, TIGIT is an inhibitory counterpart of the co-stimulatory receptor CD226. When TIGIT is present on the surface of lymphocytes, it outcompetes CD226 for CD155 binding and thus negates CD226 signaling. Second, TIGIT inhibits CD226 homodimerization in cis, preventing CD226 signaling. Third, the cytoplasmic tail of TIGIT contains an immunoreceptor tyrosine-based inhibitory motif (ITIM), which could potentially lead to inhibitory signaling.
The TIGIT/CD155 Blockade Bioassay reflects the mechanism of action (MOA) of biologics designed to block the TIGIT/CD155 interaction.
The assay consists of two genetically engineered cell lines:
TIGIT Effector Cells: Jurkat T cells expressing human TIGIT with a luciferase reporter driven by a native promoter that can respond to both TCR activation and CD226 co-stimulation
CD155 aAPC/CHO-K1 Cells: CHO-K1 cells engineered to express human CD155 with an engineered cell-surface protein designed to activate the TCR complex in an antigen-independent manner
When the two cell types are co-cultured, TIGIT inhibits CD226 activation and promoter-mediated luminescence. Addition of an anti-TIGIT antibody blocks the interaction of TIGIT with CD155 or inhibits the ability of TIGIT to prevent CD226 homodimerization, resulting in promoter-mediated luminescence.
Traditional Method
'Cells as reagents' Method
Standardized Reagents Improve Results
The TIGIT/CD155 Blockade Bioassay is a bioluminescent cell-based assay that overcomes the limitations of existing assays and can be used to measure the potency and stability of antibodies and other biologics targeting TIGIT.
Accuracy and Precision are critical to bioassays and the development of biologics. The TIGIT/CD155 Blockade Bioassay is both accurate and precise. Accuracy is a measure of how close results are to a target or reference value. Precision is a measure of repeatability. This assay was developed and prequalified according to ICH guidelines for accuracy and precision giving it the performance characteristics required for many applications of a bioassay used for antibody drug discovery research and development.
Measure of repeatability from multiple assays of the same homogeneous sample under the same operating conditions over a short time (same analyst; same lab; same day).
Measure of repeatability of multiple assays of the same homogeneous sample with different analysts or equipment or on different days.
Ability of your assay to provide measured values that are proportional to the concentration of the sample.
Repeatability (100% reference, %CV)
Intermediate Precision (%CV)
= 0.999 (50-200% range)
y = 0.974x + 3.33
TIGIT/CD155 Blockade Bioassay Technical Manual
TIGIT Effector Cells
CD155 aAPC/CHO-K1 Cells
Fetal Bovine Serum
Bio-Glo™ Luciferase Assay Buffer
Bio-Glo™ Luciferase Assay Substrate
RPMI 1640 Medium
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NOT FOR MEDICAL DIAGNOSTIC USE. FOR IN VITRO USE ONLY. BY USE OF THIS PRODUCT, RECIPIENT AGREES TO BE BOUND BY THE TERMS OF THIS LIMITED USE STATEMENT. If the recipient is not willing to accept the conditions of this limited use statement, and the product is unused, Promega will accept return of the unused product and provide the recipient with a full refund.
This product may not be further sold or transferred by the recipient and may be used only by the recipient, and then only for (1) research use, (2) discovery, development and monitoring of biologic drugs and vaccines, (3) quality assurance testing of biologic drugs and vaccines, and (4) product release assays for biologic drugs and vaccines. No other commercial use is allowed. "Commercial use" means any and all uses of this product by recipient for monetary or other consideration, including providing a service, information or data to unaffiliated third parties, and resale of this product for any use. Recipient has no right to propagate, modify, derivatize, genetically engineer or otherwise create variations of the cells or genes stably transfected within the cells. In addition, recipient must use Bio-Glo™ Luciferase Assay System purchased from Promega Corporation for all luminescence assays using this product or contact Promega to obtain a license for use of this product with reagents other than Promega's. PROMEGA MAKES NO REPRESENTATIONS OR WARRANTIES OF ANY KIND, EITHER EXPRESSED OR IMPLIED, INCLUDING AS TO MERCHANTABILITY OR FITNESS FOR A PARTICULAR PURPOSE WITH REGARDS TO THIS PRODUCT. The terms of this agreement shall be governed under the laws of the State of Wisconsin, USA.
U.S. Pat. No. 8,008,006 and European Pat. No. 1341808.
Patent Pending.
Licensed from Lonza Cologne GmbH under U.S. Pat. Nos. 7,700,357, 8,192,990 and 8,003,389, European Pat. Nos. 1297119, 1522587, 1607484 and 1741778 and other pending and issued patents.
Product cannot be used for proficiency testing.
Measure potency and stability of biologics designed to block the TIGIT/CD155 interaction.
Measure the potency and stability of biologics designed to block immune checkpoint signals.
Measure the potency and stability of biologics designed to block immune checkpoint signals
High-performance microplate reader for detecting luminescence, fluorescence and absorbance.
Stable luciferase reagent ideal for reporter bioassays.
Control antibody for the TIGIT/CD155 Blockade Bioassay and the PD-1+TIGIT Combination Bioassay.
Anti-PD-1 blocking antibody for use with the PD-1/PD-L1 Blockade Bioassay.
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Backyard Design Ideas Welcoming Your Summer Home Relaxation
Backyard Desaign Ideas with Beautifull Flower on Chic Flowerpot close Big Wooden Fence
Before summer is coming, letâ's see these backyard design ideas to set your yard becomes better spot for relaxing. Try to set again the outdoor furniture arrangement. If the furniture can be remodeled, you can do it for making the new nuance for your backyard. During summer, the season will be warm and youâ'll need time to enjoy the breezy evening. The seasonal atmosphere fits with the romantic patio set among the greenery. The trend of contemporary outdoor is simpler than traditional outdoor space.
Creating absolutely comforting private place is the main point of backyard decorating ideas. Secluded spot in your backyard should be the most comforting spot. Place it right beside the wall or on the backyardâ's corner with cozy furniture. Donâ't worry for mixing more materials, modern outdoor is constructed from various things like bricks, gravel, wood chips, or concrete. Those materials are best combined with green lawn. Whether you want rustic look or updated yard, they are amazing for yard arrangement. Making the yard looks welcoming without giving crowded sight is necessary for relaxation area.
Planting lush vegetation keeps the coziness of the yard. Plant the greenery on the wall, too since itâ's excellent with rusticity. Red brick wall is perfect with natural decoration such as green vines. This spot ambiance is fantastic for reading spot. You can spend your whole summer daylight by sitting here and read a good book. The nuance would keep you relaxed after hectic days.
Decorating the outdoor isnâ't really important for some people. They think that outdoor shouldnâ't be as beautiful as the interior. Itâ's wrong since making the outdoor like the indoor nuance will amplify the outdoor beauty. When you arrange, color, and put alluring accessories, the outdoor decoration will spoil your eyes with its beauty. Backyard patio design ideas are part of backyard plans need to be used as outdoor decorating references.
Wonderful Small Backyard Desaign Ideas with Nice Paving Pathway and Lovely Multicolored Flower
Adorable Lawn Grass close Whitee Gravel plus Wooden Stair in Backyard desaign Ideas
Lovely Backyard desaign Ideas with Large Fence and Wooden Stair close Green Grass
Awesome Backyard Desaign Ideas with Small Pool inside Brick Steeping plus Simple Chair
Alluring Small pool in Backyard desaign Ideas with Cozy Chair on Wooden Floor
Amazing Garden in Backyard Desaign Ideas with Green Lawn Grass and Cute Steeping
Fascinting Small Backyard desaign Ideas with Wooden Sitting Area on Green Lawn Grass
Bewitching Backyard Desaign Ideas with Wooden Sitting Area on Streaky Floor near Lawn Grass
Appealing Landscape in Backyard Desaign Ideas with Comfortable White Sofa on Paving PathwayGallery Tags:
More Furniture & Interior Inspiration
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Mesmerizing Kitchen Island Lighting Combined with Minimalist Kitchen Island and Chic Kitchen Extractor


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Thursday, 09 June 2016 10:46
Forty days left until the Democratic Party's convention in Philadelphia, and Bernie, just like Jesus did two millennia ago, will be trying to find answers in solitude… and fight temptation from the devil of "accommodating politics." Jesus would do it, according to the Gospels, in the wilderness without food; Bernie is likely to do it at home, in pretty Burlington (Vermont), keeping a normal diet and the company of a smart phone.
The demonstration of affection for progressivism by Democrats and honest-to-heart Independents was dealt a heavy blow by Tuesday's election results; results likely to be reinforced by President Obama's imminent endorsement of Hillary Clinton… triggered by a battle cry urgency to stop this 2016-boogeyman, Donald Trump, from branding the nation as his psycho-political casino: Fantasy-Trump-America.
It's beginning to look as if the $200 million spent by Bernie believers to bring about and promote a progressive sociopolitical agenda for America may prove not to have been in vain, as the voice of progressivism that Clinton-Husband silenced in the 1990's, might not remain totally muzzled in Clinton-Wife's prospective centrist-right platform.
Resurgent progressivism and loyal conservatism both appear to be undergoing painful castration in this 2016 presidential election; one by undemocratic and corrupt insider party politics, the other by the uglier face of bigoted-populism which might represent well over 25 percent of the nation's population. No, folks… not 5, 10 or 15 percent, but upwards of a quarter, maybe a third! This populism is responding to a demographic change in America of major transformational proportions; populism with a latent bigotry now finding an opportunity to surface as champion-du-jour, Donald Trump, singularly leads the way in "finally!" making acceptable both the vocalization and the behavior that up to now has been considered taboo, politically incorrect.
Once again we are politically marching towards another presidential election with the limited prospect of choices, most based on aesthetics, not substance; a chance to select the proverbial lesser evil or failing to select at all. Next January, either odious-Donald or odious-Hillary will be taking up White House residency, Johnson (Libertarian) and Stein (Green) having only non-critical influence in the outcome of the election thanks to our electoral system. And that brings us to why America is in such dire straits.
It's been eight decades since the start of the Spanish Civil War and the advent of that cloak-and-dagger term, "fifth column," coined by a Spanish general, Emilio Mola, and popularized in the works of an American writer, Ernest Hemingway.
A fifth column referred to a secret group that surreptitiously undermined the efforts of a larger group from within; a term perhaps a bit distant and esoteric for us today, but its meaning, whether we associate it with patriotism or with treason, remains with us no matter what we call it, or how we prefer to explain its aims and behavior.
Bill Clinton, and his then bride, Hillary, may have entered elective politics in Arkansas back in the mid-1970's using the Democratic front door, but in chameleonic fashion, as Ronald Reagan consolidated the tenets of his presidency in the 1980's, Governor Clinton was quick to mimic his own right turn in politics in the hinterlands of Arkansas. Heck, if President Reagan was then making hay advocating a smaller government and welfare reform, Bill and his Little Rock cadre of young New Democrats certainly was able to see an immediate personal future following suit embracing both issues, a plagiarized version of what The Old Gipper was preaching from the White House. After all, old soldiers may never die, but young politicians must adopt change – ideology forever damned! Or they too, like the old soldiers, could slowly (or speedily) fade away.
And Bill Clinton then, just as Bill Clinton now, was proving to be masterful at remaining politically relevant without the slightest intention of fading away. And that feverish desire for relevance as qualified and quantified in his mind by both money and power, appeared to consume not just him but his spouse as well throughout their lives. Such intense desire might have given this duo the cavalier attitude many of us see in them. It's as if this couple is intent to prove to any and all Americans that fidelity has little or nothing to do with the rule of morality, and everything to do with faithfulness to a cause, particularly when that cause is close, personal and meritoriously deserved; even if characterized by most as personal selfishness, totally lacking honesty and decorum.
Bernie will give his all to bring back progressivism to the Democratic Party, but it will be to no avail... for Americans are not yet ready for a revolution; we may still need a few more darker days in both the economy and our unintended quest in world affairs. By election time the Clintons political machine will be humming, well-greased, courtesy of Wall Street… and the fifth column will no longer have to operate in the shadows, Hillary and Bill having made fifth column deception a mainstream virtue.
© 2016 Ben Tanosborn
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Basketweave Cowl by Undeniable Glitter- Alyssa
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Basketweave Cowl
This pattern is available for free.
This cowl is made with the basketweave stitch, worked flat, blocked, and then seamed together. I enjoyed working with this beautiful color changing yarn, and this stitch, as it was my first time using both with this cowl.
I used one skein of Knit Picks Chroma Fingering in Hollyhock, with size 6 needles. The cowl is worked flat, blocked, and then seamed together. Blocking really helped flatten out the edges of this scarf, as they were curling quite a bit before.
For more information, see: http://undeniableglitter.blogspot.com/2016/07/basket...
About this pattern
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About this yarn
by Knit Picks
70% Wool, 30% Nylon
396 yards / 100 grams
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Doubletree By Hilton San Antonio Downtown29.422237296, -98.503680076
ex. Radisson Hotel San Antonio Downtown Market Square
The hotel lies in the center of an entertainment area, giving access to Arneson River Theatre, which is 1450 meters away. Founded in 1992, the hotel underwent a renovation in 2009.
Doubletree By Hilton San Antonio Downtown Hotel is also placed within a 30-minute walk of San Antonio Museum of Art . The property is set a 10-minute stroll from San Antonio center.
The hotel is set next to a museum, a theater and a palace.
Guests can reach Doubletree By Hilton San Antonio Downtown Hotel from San Antonio International airport within 20 minutes' drive.
Doubletree By Hilton San Antonio Downtown Hotel features 250 rooms across 5 floors. Bathrooms in these modern rooms are fitted with a shower, a hairdryer and a double vanity.
Eat & Drink
A continental breakfast is offered at the dining area. The casual restaurant provides special meals. Guests are welcome to the Poolside bar to relax with a drink. Mi Tierra Cafe & Bakery is about 500 meters away and serves Mediterranean, Mexican and Californian specialties.
A full breakfast is served and charges are applicable.
The facilities as a storage room, an elevator and a garage are offered for guests.
Guests will appreciate a spa centre and a hot tub provided on site. On-site fitness facilities include a gym and a fitness centre.
Wireless internet is available in public areas at USD 9.95 per day.
Guest Parking
Private parking is possible on site at USD 15 per day.
Year renovated: 2010. Number of floors: 5. Number of rooms: 250.
USD 9.95 per day
USD 15 per day
Late check-in/ -out
24-hour check-in
24-hour reception
Poolside snack bar
Coffee/Tea in lobby
Restaurant buffet
Breakfast room
Fitness centre
Outdoor swimming pool
Indoor heated swimming pool
Spa & wellness centre
Sports & Fitness
- Fitness centre
- Room service
- Self-service laundry
- Dry cleaning
- Medical facilities service
- Newspaper service
- Breakfast room
- Restaurant buffet
- Cafe
- Poolside snack bar
- Coffee/Tea in lobby
- Business centre
- Meeting/ Banquet facilities
- Fax/Photocopying
- Cots
- High chairs
Spa & Leisure
- Indoor heated swimming pool
- Outdoor swimming pool
- Leisure/ TV room
- Spa & wellness centre
- Jacuzzi
Room features
- Air conditioning
- Heating
- VIP room facilities
- Dressing area
- Tea and coffee facilities
- Turndown service
- Ironing facilities
- Rollaway beds
- Bathtub
- Hair dryer
- Free toiletries
- Television
- Telephone
- AM/FM alarm clock
Room decor
- Carpeted floor
Rooms and availability
2 Double beds2 Double beds, 1 Double bed, 2 Single beds
4 persons
In the Room
Private bathroom
Air conditioning
1 King-size bed
4 persons
In the Room
Air conditioning
1 King-size bed
4 persons
In the Room
1 King-size bed1 King-size bed, 1 Double bed
2 persons
In the Room
Air conditioning
2 Double beds2 Double beds, 1 King-size bed
4 persons
2 persons
1 Double bed
2 persons
In the Room
Private bathroom
Air conditioning
1 King-size bed
2 persons
In the Room
Air conditioning
- Nearby
- Restaurants
- City landmarks
The staff was very nice and helpful and everything was clean!
Guest rating
Reception staff was very ill-mannered and inexpert. The online reservation was processed bad, when we arrived at the hotel we had to wait almost 1 hours because they didn't find the reservation. Their suggestion was that we call to Booking and solve our problem!! Sorry but, solving attitude was horrible!!
The bed was extremely comfortable! I loved the decor of the hotel in general. I was pleased to see an energy efficient toilet and of course, I loved the warm cookies offered @ check-in.
The only thing that I didn't like about the Doubletree was the air conditioning was extremely loud in the room. Also, if you want to be in the midst of downtown (I.E. - Riverwalk), you should consider staying elsewhere. It is not within walking distance.
We enjoyed the convenience of the bus system, even though we were confused at first with the different types and colored routes. There is no public transportation near our home, so new experience, but fun. We walked almost everywhere and found the hotel convenient to the downtown area. The hotel is beautiful and well kept/clean. Our room was spacious, clean and very convenient for a traveler.
The "sleep number bed" even though considered a luxury, was not comfortable for us no matter what settings were used. We didn't always come back to a made-up bed/room and fresh towels. That was frustrating, but easily remedied with a phone call to the desk for towels.
The coffee they provided was great, and the room was comfortable
Good breakfast, the room was very clean and the beds were very comfortable. Internet WIFI in the room is free.
The hotel is very near The Mexican Market but you have to go by car to the riverwalk. Besides, the noise from the street could be heard inside the room.
The cookies were awsome, parking is free. Busy hotel with bar, and the view of the city from the top floor parking lot was great.
breakfast is not free.
Very good
Very clean and comfortable. Close to alot of activities.
Could not easily get on hwy 35 north. No continental breakfast.
Guest rating
Broken equipment in gym, electronic keys problematic (room and gym). Front desk under-staffed. Air conditioning too loud. Bathroom not cleaned (hairs in shower, mold) Clothes iron not clean. Pool not clean (a lot of debris).
Very good
Hotel staff were very good. For instance, there was a problem with the resturant bill at checkout, the staff immediately worked it out going above and beyond what I was even asking. Room was good for the price.
Restuarant service was very uneven. Sometimes attentive and sometimes you could not get served. One morning I asked for coffee from four different people, each of whom said they would take care of it and then proceeded to meander around and not bring the coffee. Did not care for parking costs or the lack of shuttle to Revierwalk.
Guest rating
Beds were comfortable.
I was very disappointed in my stay. We have stayed at many other Doubletrees and expected the same atmosphere. I understand they were just remodeled, however, in my experience, anything over 120 usually comes with amenities such as a mini fridge or microwave. There was nothing like that here. The ice machines were broken on the last 3 floors so we couldn't keep anything cool. The bathrooms have no privacy, they do not lock, they simply slide shut. The white linens where stained. All together we know we will not be staying there again.
Very good
Easy to find off of freeway. Excellent front desk staff. Lovely breakfast dining area.
Don't plan on relying on the shuttle service. We were told the shuttle would leave at the top of each hour. We waited 20 minutes, along with 17 others, and finally we all drove our own cars downtown. Downtown parking is difficult to find and expensive when you do find it.
Guest rating
Bed was comfortable.
We reserved 2 rooms with king size beds a month in advance. Called night before and confirmed reservation. When we got to the hotel, they did not have king size beds available.
|Cities nearby


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When you are faced with a clogged lead pipe then call an experienced who can support unclog your pipes and patch up your dwelling in Hillingdon WD3. Multiple the time your washing machine will share the equivalent pipes as your handbasin and when washing laundry is placed in position in the kitchen, it'll usually empty in a flash into the water closet waste upvc lead pipe A blockage in the pipes of your handbasin can stop water from getting to your washing machine. In this case, it'd be imperative to contact a plumbing engineer immediately so that they can radient an obstruction in pipes and leave you with a washing machine that works in Hillingdon WD3.


text:
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text:
Overweight mother who worried her sons would be bullied because she was a size 18, uses FACEBOOK to help her drop three stone and show others how to do it
- Kelly suffered post natal depression after the birth of her two sons
- Turning to junk food for comfort her weigh reach 14st 7lb and size 18
- Worried her boys would be teased about her size, joined a slimming group
- Although she had success, she found her motivation slipping
- Decided to start the Yummy Mummy Facebook page to document progress
- Shares recipes, diary entries and photos with other mothers
- Now has reached 11st 7lb and is a size 12 but hopes to lose another 10lb
A mother-of-two has transformed herself into a super svelte mum with the help of Facebook.
Kelly Cairns, 34, from Ryhope, Sunderland, had never struggled with her weight until she gave birth to her two sons and suffered from post-natal depression, which caused her weight to balloon to 14st 7lb and a size 18.
Worried what the other school children would say to her sons, Kelly, now a size 12, decided to do something about her weight.
Turning to food as comfort during bouts of post natal depression caused Kelly's weight to reach 14st 7lb
Kelly has lost over 3st after gaining support through a Facebook group, and intends to lose another 10lb
She started a Facebook page for recipes, diary entries and photos, and with the support of her followers has lost over three stone - with more to go.
Kelly, who runs a business from home and now weighs 11st 7lb, said: 'I started losing the weight with a slimming club, but when it plateaued I needed something to help me with the last push.
'I started the Yummy Mummy Weight Loss Plan on Facebook in August this year to help me lose the final 10lb before November.
Kelly, pictured as a size 18, says her bad eating habits continued as her sons grew up, causing her weight to keep rising
Kelly credits the support she has received and shared online with her continued weight loss success
'In the first weekend I got over 400 likes on the page - I couldn't believe it.'
Kelly first started piling on the pounds after the birth of her two sons - Rhys, nine, and Evan, seven.
She suffered with post-natal depression and turned to food as a comfort.
Kelly said: 'As the boys got older, I was stuck in bad habits and the weight continued to go on.
'I would worry what the other kids would say to Rhys and Evan at school in the playground.
'The final straw for me was when I saw a picture of myself from the side and I looked huge.
Kelly decided to start the Yummy Mummy Facebook page to document her progress and help her to get over the final hurdle and lose those last few pounds
'I had moved from Wales to Sunderland and didn't really have many friends, so stepping through the doors to the Slimming World group was a huge deal.'
Kelly's diet before
Breakfast: White toast or cereal
Lunch: Sandwich from Greggs
Dinner: Takeaway or something from a jar
Snacks: Biscuits and crisps
Kelly's diet after
Breakfast: Fruit smoothie
Lunch: Leftovers from last night or soup
Dinner: Pasta with homemade sauce or chili
Snacks: Fruit
Kelly lost the majority of her weight thanks to the group, but after leaving she missed the moral support and her weight loss slowed down.
Kelly began losing weight as she feared sons Rhys (l) and Evan (r) would be bullied over her size
During this time Kelly also started weight training. Although it helped tone her body, she lost motivation as her muscle gain also meant she put on weight.
She decided to start the Yummy Mummy Facebook page to document her progress and help her to get over the final hurdle and lose those last few pounds.
She said: 'Putting pictures online helped me see how far I've come and if I'm having a fat day then the encouragement of others helps keep me going.
'I started putting recipes up to show other mums that eating healthily doesn't have to cost a fortune.
'I never thought it would be this popular, but it's a real confidence boost.
'Now I just need to lose the final 10lbs. I'm hoping to do it by the end of November.'
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New West Grocery
4522 S 220th Pl Kent, Washington 98032
Print | Save | Directions
AboutNew West Grocery is located at the address 4522 S 220th Pl in Kent, Washington 98032.
New West Grocery has an annual sales volume of 0 - 500K. .For more information contact Tho Hang, Owner
For maps and directions to New West Grocery view the map to the right. For reviews of New West Grocery see below.
Employee Size: 1 To 4
Exact Employee Count: 3
Exact Sales Volume: 250000
Sales Volume: 0 - 500K
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26220 116th Ave Se Kent, Washington 98030
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- Phone: (206) 783-5444


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Home / are wifi garage door openers securemost secure garage door opener Tag
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- Alain F. Carpentier, Sylvain Marc Chauvaud, +7 authors Charles Dubost
- The Journal of thoracic and cardiovascular…
- 1980
Between January, 1969, and January, 1978, 551 patients with mitral incompetence were treated by a system of reconstructive techniques. Mitral valve incompetence was classified into three types… (More)
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- 1969
- Alain Carpentier, Jean Léon Guermonprez, Alain Deloche, C Frechette, Charles Dubost
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Prolapsed leaflet is the result of ruptured chordae, elongated chordae, or ruptured papillary muscle. Various techniques adapted to each of these lesions were developed, and repair of 213 prolapsed… (More)
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The incidence of beta 2-microglobulin deposits appears to increase with time on dialysis. However, the precise prevalence of the disease is not known at present because adequate, noninvasive… (More)
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Acute primary hyperparathyroidism is a rare disease with a high mortality rate in some series. Between 1960 and 1986, 1000 patients were treated for primary hyperparathyroidism, among them 59… (More)


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The family of James Byrd Jr., a Texas man dragged to his death 20 years ago, is working to preserve the memory of a racially motivated killing that shocked the nation.
Book Review
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Daily Incident Report for Thursday, August 9, 2018
Daily Incident Report for Thursday, August 9, 2018
Page Content
Fatal Crash Investigation –
On August 8 at 3:58PM, investigators from the Crash Investigation Unit responded to the area of the Prince William Pkwy and Minnieville Rd in Woodbridge (22193) to investigate a pedestrian involved crash. The investigation revealed that the drivers of a 2010 Mitsubishi Galant sedan and a 1995 Ford F-Super Duty truck were traveling northbound on the Prince William Pkwy when a road rage incident occurred. Both vehicles continued to the above area where they stopped due to traffic. As the vehicles were stopped, the driver of the pickup truck, herein referred to as a pedestrian, exited the vehicle and began to approach the Galant. At that point, the driver of the Galant maneuvered into the left lanes. In the process, the pedestrian and a 2012 Honda Odyssey minivan were struck. As a result at that collision, the pedestrian was caught between both the sedan and the minivan. Investigators are still determining which vehicle struck the pedestrian. The driver of the Galant stopped in the immediate area of the crash and contacted police. The pedestrian died at the scene as a result of his injuries. Due to the nature of the death, detectives from the Violent Crimes Bureau are investigating the incident with the assistance of the Crash Investigation Unit. No other injuries were reported. Speed, alcohol, and drug use are not factors in the collision. At this time, no charges have been placed. The investigation continues.
The pedestrian [driver from the 1995 Ford F-Super Duty] was identified as Larry Dean
, 53, of Woodbridge
The driver of the 2010 Mitsubishi Galant was identified as a
34-year-old man
of Woodbridge
The driver of the 2012 Honda Odyssey [uninvolved in the initial road rage incident] was identified as a
68-year-old woman
of Woodbridge
Armed Robbery –
On August 9 at 2:46AM, officers responded to the 7-Eleven located at 12417 Cape Cod Ct in Woodbridge (22192) to investigate a robbery. Employees of the store reported to police that an unknown man entered the business and approached them near the rear of the store. During the encounter, the man brandished a handgun and demanded money. The man took an undisclosed amount of money before fleeing on foot. No injuries were reported. A police K-9 searched for the suspect who was not located.
Suspect Description:
Black male, unknown age, 5'4"-5'"7, 125-145lbs with a small thin build and a medium complexion
Last seen wearing a gray hooded sweatshirt, black face mask, light gray pants, gloves and black & white tennis shoes
Malicious Wounding by Caustic Substance –
On August 7 at 10:17PM, officers responded to a residence located in the 15000 block of Greenmount Dr in Woodbridge (22192) to investigate a fight. The investigation revealed that three woman came to the residence to speak to a male occupant who was not home at the time. At one point, a verbal altercation ensued between the three woman and the victim, identified as a 28-year-old woman, who was a female occupant of the residence. During the encounter, two of the women, identified as the accused parties below, sprayed the victim in the face with pepper spray. Police were eventually contacted and detained all parties involved. Minor injuries were reported. Following the investigation, the two accused women, identified below, were arrested. The victim was also charged with assault for her involved in the altercation and was released on a court summons.
Arrested on August 7:
Mamyiye Isratu
, 23, of 65 Stonegate Pl, #101, in Stafford
Constance Lalita
, 36, of 19050 Fuller Heights Rd in Triangle
Both woman were charged with
malicious wounding by caustic substance
Court Date:
October 16, 2018
| Bond:
Held WITHOUT Bond
Anyone with information regarding the incidents listed in this report is asked to contact the
Prince William County Police Department
or by email at
You are now leaving the official Prince William County Government website.


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Patriot Day rotates to Vestavia Hills
The Vestavia Hills Police and Fire Honor Guard will post the colors, and Ron Higey of Birmingham International Church will offer the invocation. more
Running groups to host fundraiser for Hollywood pedestrian bridge
On Sept. 29, the groups will hold a "run social" beginning at the parking lot of Over Easy and Mexico Lindo. Andress said there will be a run from 6 to 8 a.m., with food and door prizes at the parking lot after the run. more
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There will be an art show and reception with cocktails and hors d'oeuvres at 6:30 p.m. and the seated dinner and talent show at 7:30 p.m. more
NEDA Walk at Central Park to fight eating disorders
The effort continues locally with the annual Birmingham NEDA Walk, which raises awareness and funds to support the fight against eating disorders. more
Trinity UMC to host Lil' Lambs consignment sale Sept. 13-15
Trinity United Methodist Church will transform its gym into a sales floor starting Sept. 13 with a special preview sale. more
Give for a good cause at the annual Harvest of Hope Luncheon
All funds from the event will benefit individuals and families in the Birmingham area who need financial assistance through Oak Mountain Missions Ministries. more
Mac + Cheese fest moves to Brookwood Village
Originally held in Avondale, Katie Harris-Lovoy with Community Grief Support said the move to Brookwood Village allows more space for both people and parking. more
Annual Buddy Wade golf tournament benefiting Homewood Athletic Foundation set for Sept. 18
To raise money for grants, the HAF will host its annual Buddy Wade Memorial Golf Tournament on Tuesday, Sept. 18, at the Robert Trent Jones Golf Trail at Oxmoor Valley. more
Endless stories to tell
A coffee group called 'The Has Beens' has maintained its weekly meetings for more than two decades. more
Family first
A nonprofit with Homewood ties is aiming to keep families in Congo together, while also facilitating necessary adoptions. more
Letting the garden grow
After sitting empty for several months, and years of only part-time management prior to that, Milam said her first weeks have been spent cleaning up and uncovering the garden's potential. more
Homewood resident attends Space Camp at U.S. Space and Rocket Center
The weeklong educational program promotes science, technology, engineering and math (STEM), while training students with hands-on activities and missions based on teamwork, leadership and problem solving. more
Homewood Library hosts Block Party
The fifth annual fundraiser, held Saturday, Aug. 11, featured food, games and music. more
Accordionists on the rise, according to local teacher
Accordion music and the number of students has dwindled in the Birmingham area since the 1970s. more
Retro Run brings decked-out crowd
The annual Retro Run was held July 28 in downtown Homewood. more
Homewood resident qualifies for para-cycling world championships
Jennifer Schuble will race in Maniago, Italy, Aug. 2-5. more
Get to know local law enforcement at National Night Out Aug. 7
Come get to know the men and women who protect and serve the community at National Night out on Aug. 7. more
Homewood Theatre sets 2018-19 season
After selling out nearly every performance last season, the Homewood Theatre has added an additional show and performance for the upcoming year. more
The Bell Center to host 10th annual Tailgate Challenge
To celebrate the return of football season, The Bell Center is hosting their annual Tailgate Challenge on Aug. 25. more
Birmingham Boys Choir offers food, prizes, music at 8th annual Taste of Birmingham
Birmingham Boys Choir will host its annual culinary-themed fundraiser, The Taste of Birmingham, from 6-9 p.m. on Tuesday, Aug. 21, at Haven in Lakeview. more
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