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Brett O'Donnell is a debate consultant who trains Republican candidates. He has worked with George W. Bush and John McCain, and for a short time earlier this year, he helped prep Mitt Romney.
O'Donnell is an expert on "the pivot."
If you have watched a debate, you have watched a pivot. "The pivot is a way of taking a question that might be on a specific subject, and moving to answer it on your own terms," O'Donnell says.
Take, as just one small example, a moment from the 2004 debate between President George W. Bush and Sen. John Kerry.
You could, by the way, just as easily use an example from Kerry — both Bush and Kerry used pivots roughly the same amount of the time.
In this case, the moderator, Bob Schieffer of CBS News, asked President Bush about job loss. What, Schieffer wondered, would Bush say to someone who has lost his job? Bush began by promising to "continue to grow our economy" and then, subtly, changed course. Suddenly, Bush was talking about education, specifically his signature No Child Left Behind legislation. "I went to Washington to solve problems," he explained. "And I saw a problem in the public education system."
In two or three sentences, Bush had moved from a question about lack of jobs to an answer about education and a promise fulfilled. That is the power of the pivot. Which is why, in the age of debate coaches like O'Donnell, candidates in both parties use them all the time — "frequently," O'Donnell says, "better than 60 or 70 percent of the time, I would say."
The question is, how good are viewers at identifying these "pivots" — or, in the language of my people (journalists who ask questions), "dodges"?
How good are you?
There's a man at Harvard who actually has an answer to that question.
The Pivot And The Brain
Todd Rogers, a behavioral psychologist at Harvard's Kennedy School of Government, got interested in looking at pivots, or dodges, or whatever you want to call them, after watching the 2004 Bush-Kerry debate I quoted earlier.
To him, the dodging on both sides of that debate was enraging, and he couldn't understand why others didn't feel the same.
To figure it out, he decided to do a study that tried to replicate what typical viewers see when they watch a debate.
He recorded a moderator asking candidates a series of questions.
In the first question, the moderator asked the candidates about health care in America, and the politician answered with a health care answer — a long disquisition on why Americans could not afford the care they needed.
Rogers then took that answer and used it as a response to a totally different moderator question, this one about the problem of illegal drug use. So one set of people saw a candidate answering a health care question with a health care answer, while another group saw an illegal-drug use question answered with a health care answer. Essentially, the second group saw a relatively subtle pivot, from drug use question to health care answer.
Finally, he had a third group view the moderator asking a question about terrorism, which was answered again with the exact same health care answer — a much more blatant shift.
At the end of this he asked the different groups two things:
Can you remember what question the person was asked?
How honest, likable and trustworthy is this person?
'Exploiting Our Cognitive Limitation'
What he found was that when a politician answered the health care question with a health care answer, viewers could recall the question and thought the candidate was likable, honest and trustworthy.
When the politician pivoted a little bit and answered the illegal drug question with a health care answer, viewers could not recall the question — but they didn't penalize the politician at all. "Listeners thought he was just as honest, trustworthy and likable as the guy who actually answered the question," Rogers says.
It was only when the politician answered the terrorism question with a health care answer that people could actually tell. "Everyone noticed, and they thought he was a jerk," Rogers says.
This led Rogers to the conclusion that people are capable of detecting dodges — but only if they're egregious. They don't seem capable of detecting subtle evasions.
Rogers believes this is because we have limited attention, and most of the time when we're watching debates, we spend that attention on social evaluation — Do we like this person? Do we trust this person? — and only generally monitor content.
It's only when the speaker is wildly inconsistent that some deep mental wire is tripped. "It raises some flags, and we direct our limited attention to assessing whether this person is doing something unusual by failing to answer the question and offering an egregiously different answer," Rogers says.
This, Rogers believes, is why politicians can get away with dodging questions as much as 70 percent of the time.
"Politicians," he says, "are exploiting our cognitive limitation without punishment."
Years ago, I asked a government official a question. He said some words, but was candid about candid about not being candid. Notice he said, I am addressing your question, not answering it. It's worth recalling that difference as we prepare for a presidential debate tonight. Let's examine one of the techniques that candidates have used in the past to turn debate questions to their advantage. The technique is called the pivot by political professionals who do debate prep. And as NPR's Alix Spiegel reports, audiences are not very good at spotting it.
ALIX SPIEGEL, BYLINE: If you have watched a debate, you have watched a pivot.
BOB SCHIEFFER: New question, Mr. President.
SPIEGEL: It is 2004, the third debate between President George Bush and Senator John Kerry. And the moderator, Bob Schieffer of CBS, has a question. He wants to know what President Bush would say to a worker who has lost his job...
SCHIEFFER: ...lost his job to someone overseas.
PRESIDENT GEORGE W. BUSH: I say, Bob, I've got policies that continue to grow our economy and create the jobs of the 21st century. And here's some help for you to go get an education.
SPIEGEL: There. Right there is the pivot. The moment Bush moves from a question about lack of jobs to an answer about education - specifically, Bush's signature No Child Left Behind legislation.
BUSH: I went to Washington to solve problems. And I saw a problem in the public education system in America. They're just shuffling too many kids through the system year after year, grade after grade without learning the basics.
SPIEGEL: Classic pivot. And according to debate consultants, candidates who are effective debaters, both Republicans and Democrats, use these pivots more or less constantly.
BRETT O'DONNELL: Frequently, better than 60 or 70 percent of the time, I would say.
SPIEGEL: This is Brett O'Donnell. O'Donnell is a debate consultant who trains Republican candidates. He's worked with George W. Bush, with John McCain, and for a short time earlier this year, with Mitt Romney. And for O'Donnell it is very clear, the pivot, it is critical for candidates.
O'DONNELL: The pivot is a way of taking a question that might be on a specific subject and moving it to answering it on your terms that best advances the message of the campaign.
SPIEGEL: Debates are not about debating, he tells me. They're about delivering a message to voters. And that's why you need the pivot, so you can quickly get to your message. And this view, by the way, is not unique to Republicans. Sam Popkin, a debate strategist who's helped at least two Democratic presidents develop their own pivots, agrees with O'Donnell.
SAM POPKIN: It's a sincere sounding evasion of the question.
SPIEGEL: So you mean a pivot is a dodge.
O'DONNELL: It's a dodge.
POPKIN: It's a dodge.
SPIEGEL: It's a dodge. And if it's a good dodge it is totally invisible.
POPKIN: When it feels right, you don't notice.
O'DONNELL: If you get that the candidate is pivoting, then it's an ineffective pivot.
SPIEGEL: So how good is the average viewer at detecting the average pivot? There's a man at Harvard who actually has an answer to that question.
TODD ROGERS: My name is Todd Rogers. I am an assistant professor of public policy at the Harvard Kennedy School.
SPIEGEL: Todd Rogers got interested in looking at dodges, or pivots, or whatever you want to call them, after watching the 2004 Bush/Kerry debate that you heard earlier. To him, the dodging on both sides of that debate was enraging, and he couldn't understand why others did not feel the same.
And so to find out, Rogers decided to do a study which tried to test what a typical viewers sees when they watch a debate. Here's what he did.
ROGERS: We record a moderator asking a politician a question. Moderator will say...
UNIDENTIFIED WOMAN: Candidate one, what will you do about the...
ROGERS: What will you do about the health care problem in the America? The politician will say, I'm glad you asked me that.
UNIDENTIFIED MAN: I'm glad you asked this question. There's so many challenges facing America today. Many of our problems have arisen because too many Americans cannot afford the care that they need.
SPIEGEL: So, a health care in gets a health care answer.
But what would happen if you gave the same answer to a question about illegal drugs? Or even a question about terrorism? The viewers noticed when the answers are not responsive. And if they notice, do they hold it against the candidate?
Here's what Rogers found. When the question and the answer are about the same topic, like health care with health care, viewers...
ROGERS: Can recall the question asked, and they think that, you know, he's a likeable, honest and trustworthy.
SPIEGEL: When the question was about illegal drugs and the answer was about health care though, viewers suddenly couldn't remember the question. And because they couldn't remember the question, they didn't notice the dodge, and so didn't hold dodging against the politician.
ROGERS: Listeners thought he was just as honest, trustworthy and likable as the guy who actually answered the question.
SPIEGEL: It was only when the politician answered a terrorism question with a health care answer that people could actually tell.
ROGERS: Everyone noticed, and they thought he was a jerk.
SPIEGEL: Which led Rogers to this conclusion.
ROGERS: People are capable of detecting dodges - but only if they are very egregious. They don't appear to be capable of detecting subtle dodges.
SPIEGEL: Rogers says this is because we have limited attention, and most of the time when we are watching debates, we spend that attention on social evaluation - do we like the person? Are they trustworthy? And we're only generally monitoring content - unless the question and the answer are really, really far apart.
ROGERS: It raises some flags, and we direct our limited attention to assessing whether this person is doing something unusual by failing to answer the question and offering an egregiously different answer.
SPIEGEL: Rogers says this is why politicians can get away with dodging questions as much as 70 percent of the time.
ROGERS: Politicians are exploiting our cognitive limitation without punishment.
SPIEGEL: Now Rogers thinks that if the networks simply printed the moderator's questions at the bottom of the screen while the candidates answered, it would really help viewers; it would help them identify the dodging, and also it would make the voters better informed.
ROGERS: It's specifically the questions that politicians don't want to answer that we actually need answers to.
SPIEGEL: But Brett O'Donnell, the Republican debate coach, doesn't think it will work. O'Donnell pointed out that during the Republican primary debates, CNN put the questions at the bottom of the screen as the candidates answered and even told the candidates before the debate that they were going to do that. But he says it didn't change how the candidates answered.
And as for viewers?
O'DONNELL: Don't think it's going to fix the problem. You know, first of all, most people are picture primacy anyway - more interested in looking at the candidate than reading on the screen. But I don't think there is a problem, to be honest with you. I think that when candidates stretch pivots too much the public will understand that they've not answered the question. And when don't stretch them, and they're pushing out their vision, I think that's a healthy thing.
SPIEGEL: Researcher Todd Rogers disagrees. He says he's already done another study that shows that printed questions do help watchers see pivots.
But as to whether ones identified - those viewers will see the pivots as a problem - that, Rogers says, he will leave for the viewers themselves to decide.
Alix Spiegel, NPR News, Washington.
INSKEEP: You're listening to MORNING EDITION from NPR News. Transcript provided by NPR, Copyright NPR.


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By Elizabeth Daley
PITTSBURGH (Reuters) - One person was injured and another was missing after an explosion and fire on Tuesday at a natural gas well owned by Chevron Corp in southwestern Pennsylvania, a company spokesman said.
The blast occurred around 6:45 a.m. local time at Chevron Appalachia's Lanco 7H well in Dunkard Township, about 50 miles south of Pittsburgh.
"One employee of a contractor is currently unaccounted for and another contractor employee was taken to the hospital for minor injuries and has since been released," Chevron spokesman Kent Robertson said in an email.
The Lanco well pad has three natural gas wells. Nineteen workers were on the well pad during the explosion, Robertson said, adding a fire continued to burn.
"At the time of the incident, preparations were being made to run tubing, which is often done prior to bringing wells into production," Robertson said.
There was no drilling or hydraulic fracturing at the time, he said.
Robertson said the company did not immediately know the cause of the explosion. Wild Well Control, an organization trained specifically to deal with natural gas explosions, was on site, he said.
"Chevron's primary concern at this point is to contain the fire and ensure the safety of its employees, contractors and the surrounding community," Robertson said.
(Writing by Ian Simpson and Eric M. Johnson; Editing by Edward McAllister and Chizu Nomiyama)

subset: commoncrawl


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Elan's beyond-the-plaque Alzheimer's med gets fast-tracked
The FDA put Elan's experimental Alzheimer's medication ELND005 on the approval fast track. The company announced the expedited status Wednesday in a statement with its partner, Toronto-based Transition Therapeutics, from whom Elan licensed the therapy.
Just as Otsuka and Lundbeck are going beyond tau tangles and plaques, Elan is approaching the brain-degeneration disease from a different angle. Elan's experimental drug focuses on agitation and aggression that is found among moderate-to-severe Alzheimer's disease patients. The companies said in a statement that ELND005 Phase II results "appeared to decrease the emergence and severity," of aggression and agitation. The companies said that around 60% of AD patients develop agitation and aggression. The Otsuka/Lundbeck effort, which is gearing up for Phase III testing, focuses on cognitive function among moderate Alzheimer's patients.
Elan's focus on later-stage patients may be considered a retroactive pursuit, in light of recent discussions that arresting the disease may be effective before it takes hold, but a need for downstream treatments remain critical. Non-profit advocacy group the Alzheimer's Association says that one-third of seniors will die of Alzheimer's or another form of dementia. The group also notes that Alzheimer's-related deaths rose 68% between 2000 and 2010, and the number of AD patients is only expected to increase.
Among those pursuing late-stage treatments are Eli Lilly, which is reframing its experimental drug solanezumab as a possible treatment for mild Alzheimer's disease patients. The drug failed among its initial target—moderate patients—but that there was a positive read among a small subset of patients. Its newest round of trials will focus on mild patients, and recruitment will be limited to patients who test positive for beta-amyloid, which is thought to be a possible trigger for Alzheimer's disease.
Eli Lilly, for example, is repositioning its experimental drug solanezumab further upstream. The drug failed among later stage patients, but the company found a possible positive result if it pooled data from a subset patient group and pooled data from two trials. The company's new effort will focus on this subset—mild patients. The company is also requiring candidates to test positive for beta amyloid to enter the trial.
Merck is also following the beta-amyloid lead, and announced Sunday that its Phase Ib BACE inhibitor showed progress among mild-to-moderate AD patients. The company released its data at the Boston Alzheimer's Association International Conference and said it was expanding its research into Phase II tests, which will include up to 1,700 patients. BACE inhibitors act on precursor proteins which lead to amyloid plaques. The inhibitors seek to block this action, and drug makers including Roche and AstraZeneca are among those pursuing this approach. Lilly abandoned its Phase II BACE inhibitor last month over liver abnormalities among clinical trial patients. The company said it did not think the liver abnormalities were linked to the BACE inhibitor.


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Friday , March 09, 2018 - 5:00 AM
OGDEN — Clocks aren't the only thing springing forward this weekend. Ogden's women of roller derby hope to spring past an opponent that basically cleaned their clocks last year.
On Saturday night, the Junction City Roller Dolls will host "Daylight Skatings," the league's season opener, at the Golden Spike Event Center. The rock-'em, sock-'em contest on roller skates will feature local favorites Junction City Trainwrecks and the Wyoming-based Jackson Hole Juggernauts.
The event begins at 6 p.m. Saturday, March 10, in the Exhibit Hall of the event center at 1000 N. 1200 West in Ogden. Doors open at 5 p.m.
RELATED: Roller Dolls do derby right
Jamie Trujillo, a member of the Junction City Roller Dolls, says roller derby is a fast, action-packed sport.
"We've been referring to it as 'Not your mama's roller derby,'" Trujillo said. "It is a full-contact sport. It's not scripted like it was back in the 1980s when it was more like WWE wrestling."
Roller derby involves two five-woman teams on roller skates, competing on an oval-shaped flat track. One player from each team is designated the "jammer." Jammers score points by passing everyone on the opponent's team. The rest of the women on the track try to help their own jammer score points while keeping their opponent's jammer from passing them.
RELATED: For Ogden's Trainwrecks, roller derby is serious business
The participants usually take on derby nicknames, similar to a stage name. Trujillo's is TruRebel.
"It's like my alter ego," she said. "As Jamie T., I wouldn't even jaywalk. But when I'm TruRebel on the track, it's all free game."
Trujillo says they're hoping for some payback this year against the Jackson Hole Juggernauts.
"We played them last year and they slaughtered us — like, 200-some points to 90," she said.
The evening will feature a sanctioned bout, as well as a co-ed scrimmage.
Tickets are $10 in advance, from brownpapertickets.com or a roller derby athlete. Admission is $12 at the door. Children 12 and younger are admitted free.
The 2018 Junction City Roller Dolls season will also include two competitions in April, one in August and one in October.
Contact Mark Saal at 801-625-4272 or email@example.com. Follow him on Twitter at @Saalman. Friend him on Facebook at Facebook.com/MarkSaal.
Sign up for e-mail news updates.


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Sinclair Community College was chosen to receive the 2012 Award for Outstanding Student Services from the Instructional Technology Council (ITC). This award is presented every year to an organization that has built a solid reputation for outstanding service for their online students - on campus and off campus. Sinclair has proven that their services are replicable and innovative. Winners are held to the high best-practice standards exemplified by previous ITC award winners.
The Bellwether Awards recognize outstanding, trend-setting programs and practices that are successfully leading community colleges into the future. Applications for the awards are competitively peer reviewed by a panel of judges that selects 10 finalists to present at the Community College Futures Assembly. At the Assembly, each finalist college gives a presentation, which is judged according to how well it addresses need, results, strategy and capacity. In addition, the program is measured on its sustainability and its impact on the workforce of 2020.
Every year ITC asks its members to nominate an exemplary eLearning program that has demonstrated leadership and replicable innovation in several areas: ensuring quality instruction, excellent course and degree development, instituting effective retention strategies, promotion, providing appropriate student services, and outstanding faculty professional development.
ITC provides leadership, information and resources to expand and enhance distance learning through the effective use of technology. An affiliated council of the American Association of Community Colleges established in 1977, ITC represents higher education institutions in the United States and Canada and is a leader in advancing distance education.
The contest was searching for new mobile applications (apps) that showcase the talents and creativity of Ohioans, and highlights what is unique to Ohio. eTech Ohio encourages mobile application developers, both new and experienced, to produce apps that will increase awareness and usage of mobile apps in Ohio. The purpose of this contest was to increase awareness, interest, and knowledge of mobile applications development in Ohio and to increase usage of educational mobile applications in Ohio.
Skeletal PAL is a mobile application directed toward the study of human anatomy. PAL features a series of inter-linking puzzles that match bone images to teach skeletal structures and their correlating articulations in the human body.
Download Skeletal PAL for Android on the Android Marketplace.


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Observe que a Coinbase já não tem compatibilidade com este navegador. Recomendamos a atualização para o Google Chrome ou Firefox mais recente.
San Francisco, CA
Our vision is to bring more innovation, efficiency, and equality of opportunity to the world by building an open financial system. Our first step on that journey is making digital currency accessible and approachable for everyone. Two principles guide our efforts. First, be the most trusted company in our domain. Second, create user-focused products that are easier and more delightful to use.
Moving and transacting financial assets safely is core to executing on our vision and building our brand of trust. The payments team builds shared infrastructure for Coinbase and GDAX to securely store and trade billion dollars of assets. We take on hard engineering problems in cryptography, security, blockchain technology and distributed systems, with a focus on building high reliability services for product teams.
On payments, you will be tasked with helping Coinbase and GDAX expand to new markets and assets. You'll work closely with product, infrastructure, fraud and security teams to add new cryptocurrencies to our platform, and to help expand to new countries around the globe. You will also be responsible for designing, building and maintaining scalable software systems used by over 9 million customers use to trade cryptocurrencies.
A little about our team: we take continuous learning to heart. We often dive into computational, financial and economic theory to better understand the engineering problems we face. We also make sure that we have the best tools for the job - we are thoughtful about code quality, testing and architecture, we push code to production confidently multiple times a day, work primarily on microservices and have great monitoring, alerting and debugging tools for production. We also value positive energy, and clear communication and are committed to building an inclusive environment for people from every background.
Nice to Haves
We are an equal opportunity employer and value diversity at our company. We do not discriminate on the basis of race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status.


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The HKTDC Hong Kong Toys & Games Fair kicked off Monday at the Hong Kong Convention and Exhibition Centre (HKCEC). The fair, organized by the Hong Kong Trade Development Council (HKTDC), runs through Thursday, January 12. Three complementary fairs—the Hong Kong International Stationery Fair (staged by HKTDC and Messe Frankfurt (HK) Ltd.), the Hong Kong Baby Products Fair, and the HKTDC Hong Kong International Licensing Show—are also running concurrently with the toy fair.
The 38th Toys & Games Fair is welcoming first-time participants from Greece, Macau, Russia, and Ukraine. Group pavilions are bringing together companies from the Chinese mainland, India, South Korea, Spain, Taiwan, and Thailand. Other highlights include the World of Toys Pavilion, a new Animal Kingdom product zone, the return of the Eco Toys Display Zone, and the Brand Name Gallery, which boasts a record 80 exhibitors—30 percent more than last year. The Hong Kong Toys Conference looks at the latest safety directives from the European Union and the U.S.
This post was originally written by Elizabeth A. Reid and published by ToyBook.com. For more news, visit www.toybook.com, follow The Toy Book on Twitter, and like The Toy Book on Facebook. The Toy Book is a bimonthly trade magazine covering the toy industry, published by Adventure Publishing Group.


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v. -- pon·dered, pon·der·ing, pon·ders
v. tr. -- To weigh in the mind with thoroughness and care.
v. intr. -- To reflect or consider with thoroughness and care.
Welcome to Pondered.org. Almost every day we pick a topic, any topic and 'ponder' it. We think about it. We research it. We look into it. We give it a bit of thoroughness and a bit of care. Then we write about it... And we post it here.
Randomness is the key here: We're talking about a wide variety of topics: from educational topics like online degrees, online colleges, and online universities, to tax attorneys and lapel pins, even a little info on oscilloscopes thrown in for fun. Anything and everything… Nothing really is to'out there' for us!
Sound like fun? Well, honestly, it is. To us, at least. We enjoy picking a random topic, thinking about it for a bit, scratching a few words onto paper, and tossing up an article that just might help one person, or maybe (If we're lucky) even two. We learn something, they learn something, everybody's happy... So, check it out: Read an article or two. Have fun. Learn something. We did...


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The years 1751–52 marked a turning point in Washington's life, for they placed him in control of
Mount Vernon
. Lawrence, stricken by
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, went to Barbados in 1751 for his health, taking George along. From this sole journey beyond the present borders of the United States, Washington returned with the light scars of an attack of smallpox . In July of the next year, Lawrence died, making George executor and residuary heir of his estate should his daughter, Sarah, die without issue. As she died within two months, Washington at age 20 became head of one of the best Virginia estates. He always thought farming the "most delectable" of pursuits. "It is honorable," he wrote, "it is amusing, and, with superior judgment, it is profitable." And, of all the spots for farming, he thought Mount Vernon the best. "No estate in United America," he assured an English correspondent, "is more pleasantly situated than this." His greatest pride in later days was to be regarded as the first farmer of the land.
He gradually increased the estate until it exceeded 8,000 acres (3,000 hectares). He enlarged the house in 1760 and made further enlargements and improvements on the house and its landscaping in 1784–86. He also tried to keep abreast of the latest scientific advances.
For the next 20 years the main background of Washington's life was the work and society of Mount Vernon. He gave
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attention to the rotation of crops, fertilization of the soil, and the management of livestock. He had to manage the 18 slaves that came with the estate and others he bought later; by 1760 he had paid taxes on 49 slaves—though he strongly disapproved of the institution and hoped for some mode of abolishing it. At the time of his death, more than 300 slaves were housed in the quarters on his property. He had been unwilling to sell slaves lest families be broken up, even though the increase in their numbers placed a burden on him for their upkeep and gave him a larger force of workers than he required, especially after he gave up the cultivation of tobacco. In his will, he Angara Classic Three Stone Swiss Blue Topaz and Diamond Engagement Ring Z1XymMCDnB
the slaves in his possession to his wife and ordered that upon her death they be set free, declaring also that the young, the aged, and the infirm among them "shall be comfortably cloathed fed by my heirs." Still, this accounted for only about half the slaves on his property. The other half, owned by his wife, were entailed to the Custis estate, so that on her death they were destined to pass to her heirs. However, she freed all the slaves in 1800 after his death.
For diversion Washington was fond of riding, fox hunting, and dancing, of such theatrical performances as he could reach, and of duck hunting and sturgeon fishing. He liked billiards and cards and not only subscribed to racing associations but also ran his own horses in races. In all outdoor pursuits, from wrestling to colt breaking, he excelled. A friend of the 1750s describes him as "straight as an Indian, measuring six feet two inches in his stockings"; as very muscular and broad-shouldered but, though large-boned, weighing only 175 pounds; and as having long arms and legs. His penetrating blue-gray eyes were overhung by heavy brows, his nose was large and straight, and his mouth was large and firmly closed. "His movements and gestures are graceful, his walk majestic, and he is a splendid horseman." He soon became prominent in
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affairs, was an active member and later vestryman of the Angara Round Peridot Split Shank Ring with Diamond Halo hrBELl
, and as early as 1755 expressed a desire to stand for the Virginia Angara BezelSet Morganite Teardrop Earrings with Diamond Accents 7PZblib
Singapore continues to perform its traditional function as a financial intermediary, shipping raw materials such as rubber, timber, and spices from the Southeast Asian region in exchange for finished goods from both within and, especially, outside the region. Major imports are machinery and transport equipment and crude petroleum, while machinery and refined petroleum products are the major exports. China, the United States, Indonesia, Malaysia, and
are Singapore's principal trading partners.
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activities, where goods are transhipped and sometimes processed or manufactured in the immediate area, account for about one-third of Singapore's export trade. Notable in this capacity has been the oil-refining industry. In an attempt to foster additional trade, Singapore has become a joint-venture partner in numerous projects with Malaysia and Indonesia. Investments in the nearby Indonesian island of Batam have been important in this respect.
Singapore has one of the world's busiest ports in terms of shipping tonnage. The Port of Singapore Authority oversees all shipping activity and operates a number of terminals on the island. Containerized cargo accounts for more than half of the general-cargo tonnage. The island has a well-developed network of roads and highways, but traffic congestion frequently is a serious problem. In the late 1980s and early 1990s the government opened a light-rail mass-transit system that links the major population centres in the housing estates with employment centres and the central business district. Singapore is linked by rail to
Peninsular Malaysia
via the connecting causeway at Johor. Singapore's international airport,
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, at the eastern end of the main island, is a major regional and overseas air hub.
Singapore is a unitary
parliamentary democracy
based on the Westminster model. The president is head of state; until 1991 the largely ceremonial post of president was filled by parliamentary election, but in that year the constitution was
to allow for the direct popular election of the president and for presidential powers to be expanded. The unicameral Parliament consists of 94 members, of whom 84 are elected and 10 are appointed to terms of up to five years. The parliamentary majority selects the
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, who is head of government, and the cabinet from its own ranks, and they in turn form the government. In each constituency there is a Citizens' Consultative Committee, designed to link local communities to the ruling party.
Religious affiliations reflect ethnic patterns. About two-thirds of all Chinese profess some degree of attachment to
, Buddhism, or Daoism or to some combination thereof. Virtually all Malays, and some Indians, adhere to
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, which is the formal religion of about one-seventh of the population. The Christian community has grown rapidly to become comparable in size to the Muslim population; nearly all Christians are Chinese. Almost all of the remaining population practicing a religion is Hindu, but there are also many Singaporeans who have no religious affiliation.
Heavily urbanized, Singapore has a high population density, but it also has been a regional leader in population control. Its birth and population growth rates are the lowest in
Southeast Asia
. Singapore's high average
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and its low infant-mortality rate reflect high standards of hygiene and access to a superb health care system. The low birth rate and greater longevity of the population have raised the median age, a trend also occurring in other developed nations.
Singapore, one of the great
entrepôts of the British empire, has experienced remarkable
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and diversification since 1960. In addition to Angara Marquise Round Tanzanite Cross Pendant LBLplPA
its position as a world trade centre, it has developed powerful financial and industrial sectors. Singapore has the most advanced economy in Southeast Asia and is often mentioned along with other rapidly industrializing countries in Asia, notably South Korea and Angara Marquise Cut Sapphire and Diamond Ring in White Gold bBsJfy98
. Singapore's economy always has differed from those of the other Southeast Asian countries in that it never has been primarily dependent on the production and export of commodities.
Economic development has been closely supervised by the Singaporean government, and it has been highly dependent on investment capital from foreign
multinational corporations
. The government holds about three-fourths of all land and is the chief supplier of surplus capital, which is derived largely from contributions to the Central Provident Fund (CPF) social-security savings program. In addition, the government has attempted to
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the value and productivity of labour in order to attract investment and boost export competitiveness. This has been accompanied by a strong commitment to education and health. Labour shortages and rising wages have heightened the push for restructuring the economy even more toward higher value-added production.


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METAIRIE — With no playoff games to look forward to and the season finale coming Sunday, some New Orleans Saints began the process of taking a long look around the locker room on Wednesday.
It happens every year in the NFL, but the Saints, for the past three seasons anyway, have been thinking about the postseason — not who will or won't be around when they reconvene for offseason workouts in April.
"This is a business. … Everyone knows that no team is going to be the same year in and year out," middle linebacker Curtis Lofton said.
Lofton should know. Last year at this time, he was completing his fourth season with the Atlanta Falcons. Less than three months later, he was with the Saints after signing a four-year contract as an unrestricted free agent.
"It changes, but at the same time you cherish the moments that you have with these guys and relationships that will continue for years and years," Lofton noted. "You just go out this last game, have fun and enjoy each other's company."
That's what some Saints will be thinking about when they take the field Sunday for the season finale against the Carolina Panthers in the Mercedes-Benz Superdome.
While they aren't scheduled to have nearly as many high-profile free agents as a year ago when quarterback Drew Brees, guard Carl Nicks, wide receivers Marques Colston and Robert Meachem, and cornerback Tracy Porter were set to go on the market, they have a few.
As of Wednesday, 18 Saints had contracts that will expire at the end of the league year in early March. The list included 10 unrestricted free agents who will be free to sign with any team.
The biggest names on the UFA list are tackle Jermon Bushrod, defensive tackle Sedrick Ellis, wide receiver Devery Henderson and linebacker Scott Shanle, although Shanle, a 61/2-year starter, was phased out of the defense at midseason.
When asked how much turnover he expected this offseason, Brees said he hadn't thought a lot about it because they were focused on finishing the season strong and winding up 8-8 after being 5-8 three weeks ago.
"You always expect it a little bit, so you kind of just wait and see," said Brees, who signed a five-year, $100 million contract in July after being designated the team's franchise player. "I don't think it's going to be any different than any other year."
When Bushrod's name came up, Brees voiced his approval to get him back. Brees lost Nicks, a two-time Pro Bowl selection and an All-Pro, to the Tampa Bay Bucs last spring.
"Jermon Bushrod has certainly cemented himself as one of the best left tackles in this league," Brees noted. "Obviously, I want him back. … I'd love to have him back.
"I understand how this business works and everything else, but we'll wait and see how all that transpires. But man, I really hope he's back with us."
Bushrod, who was selected to the Pro Bowl last season, spoke whimsically Wednesday about his six years with the Saints while expressing hope that he'll return.
A fourth-round draft pick in 2007, he got into the starting lineup two years later and has been a big part of the Saints' offense for four seasons after signing a two-year contract extension in 2011.
"I really don't like talking about it," Bushrod said when asked about what may happen. "It's a good position to be in, but at the same time it's a bad position to be in.
"I've established a great relationship with the guys, and I have a family here. But you've got to let the business side take care of itself, and we'll work it out."
Bushrod wouldn't say whether he sought a longer contract when he negotiated a new deal after the players' lockout ended in August 2011, saying some things need to remain private.
But he said he was happy at the time because he wanted to earn it before getting another opportunity — hopefully with the Saints again.
"Whenever I start to think about it … I have no control over what's going to happen," Bushrod said. "The more I think about it, the more stressed I get. Whatever happens happens, and everybody is going to be all right."
Henderson, a nine-year veteran who joined the Saints as their second-round draft pick in 2004 out of LSU, said he hasn't talked to club officials about how or if he fits into their plans next season after seven successful years with one of the NFL's most productive offenses.
He has twice been an unrestricted free agent and rejected offers from the Bucs both times to remain with his home-state team to continue his career than now includes 123 games with 77 starts.
Like Bushrod, he doesn't like to talk about what may happen.
"Sometimes guys may be frustrated or discouraged, so it's easy to say he might think about going other places," Henderson said. "I just keep my head up and think positive. It's all Saints, and that's just my approach until it changes."
Shanle, who has started 93 of 97 games since coming to the Saints in a trade in 2006, has already seen the writing on the wall after being a healthy inactive for eight of the past nine games.
Shanle said he might think more about it being his final game on Sunday if he were out there playing 70 snaps. But he said he's had plenty of time lately to reflect on his career with the Saints.
"I've had time to kind of look back at all the things that have been great about being part of this organization," he said. "Whatever happens, I'm ready for, regardless if it's going someplace else, coming back or doing something entirely different in my life — I'll be ready for it."
Saints potential free agents
Unrestricted: Tackle Jermon Bushrod, linebacker Jonathan Casillas, quarterback Chase Daniel, defensive tackle Sedrick Ellis, wide receiver Devery Henderson, linebacker Ramon Humber, cornerback Elbert Mack, defensive end Turk McBride, wide receiver Courtney Roby, linebacker Scott Shanle.
Restricted: Center Brian de la Puente, long-snapper Justin Drescher, running back Chris Ivory.
Exclusive rights: Safety Rafael Bush, tight end Michael Higgins, guard/center Eric Olsen.


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Enjoy your visit, and come back!
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Positioning herself to perfectly execute a winning shot is something Caroline McCarthy does well. Last summer, however, she never could have imagined that a tie-breaking point in a game would land her in South Shore Hospital's emergency department with a severe wrist fracture. "I was shocked, because I've never broken anything," Caroline recalls. "My biggest fear was that I may never be able to play tennis again." At 15, with aspirations to bring her talent to the court in college, it was hard to fathom the thought of giving up the sport she loves.
Caroline was referred to Dr. Glen Seidman, an orthopedic surgeon, who specializes in hand surgery. "Dr. Seidman was so encouraging from the moment I met him. He assured me that he would repair my wrist and get me back on the court." Within three days, he was performing surgery on Caroline's wrist, to bring back normal function in the joints involved.
Caroline completed occupational hand therapy — and finally regained full function of her wrist. It was a celebratory day when she met with Dr. Seidman, reporting she was pain-free and back on the court, only a few short months after surgery.
Now in her junior year at Carver High School, Caroline sparkles when asked about her post-recovery tennis. "Dr. Seidman and the South Shore Hospital team were amazing! I'm just so grateful that I can play again," she remarks.
South Shore Hospital's Outpatient Center for Orthopedics, Spine and Sports Medicine in Hingham is now making undergoing treatment of musculoskeletal dysfunction much more manageable. "In Caroline's case, many different locations were required for treatment. The new center in Hingham eliminates this headache with a coordinated approach," Dr. Seidman explains. "Colleagues working together under the same roof coupled with the latest techniques in hardware bring improved patient results – all in an outpatient atmosphere."
Introducing South Shore MyChart, the new and improved Patient Portal.
No matter what you're facing, receiving exceptional, unified care is non-negotiable. That's why we're bringing people, caregivers and excellence in medicine together. As One.
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South Shore Health Systems: >> See all


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Britney Spears spent $6.8 million of her fortune last year (12), running up huge tabs at a range of fast food restaurants and blowing $3,400 on Christmas lights for her home.
The Toxic hitmaker spent almost $40,000 on clothes, hair and make-up, including $500 on a manicure, but legal documents obtained by editors at TMZ.com also reveal she is a keen bargain hunter who enjoys shopping at cut-price stores such as 99 Cents Plus.
Spears also ran up tabs at fast food takeaways including McDonald's, In-N-Out Burger, Domino's Pizza, and El Pollo Loco.
The papers reveal Spears' back catalogue and trademarks earned more than $14 million throughout 2012, on top of her reported $15 million salary for her stint as a judge on The X Factor.


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2013 and earlier-Mercedes-Benz SLK Lease Questions
kyfdx Posts: 88,617
edited May 2015 in Mercedes-Benz
For current leasing information, go to 2015 Mercedes-Benz SLK Lease Questions
For current pricing information, go to Mercedes-Benz SLK Prices Paid
Ask your Mercedes SLK lease questions here!
For current pricing information, go to Mercedes-Benz SLK Prices Paid
Ask your Mercedes SLK lease questions here!
Prices Paid, Lease Questions, SUVs
slk280 Posts: 2I am in southern California and want to lease this vehicle for a term of 36-42 months [whatever will get me the best payment] at 12,000 miles per year. My questions are: (1) what should I expect to actually pay [cap cost]; (2) what kind of residual percentage is appropriate for this car [I hear it has the highest residual for its market segment]; and (3) what kind of money factor can I expect for a deal completed by march 31st?
While this may be off-topic I was hoping for some additional input. My trade is a 2003 Acura TL Type-S in pristine condition with only 27,500 miles, brand new Michelin speed-rated tires with a little under $20,000 owed. My research shows that I shouldn't have any trouble getting out of the vehicle with out rolling anything into the lease and may be able to actually get $500 towards the SLK. Any thoughts to the contrary?
Hello slk280. I am not personally all that familiar with what the market is like for this particular model right now. I can tell you though that the roadster segment is not exactly hot right now. Most consumers are able to get pretty good deals on them. For more specific info on this model, try stopping by the following discussion: "Mercedes-Benz SLK: Prices Paid & Buying Experiences".
As far as its lease program goes, if you were to lease a 2006 Mercedes-Benz SLK280 through Mercedes-Benz Credit right now for 39 months with 12,000 miles per year, its buy rate lease money factor and residual value should be .00240 and 61%, respectively.
Smart Shopper / Prices Paid Forums0
lopz Posts: 22How does one arrive at lease monthly payments from the money factor and the residual value? Thank you.0
trini47 Posts: 1I bought a 2005 Mercedes SLK 55 AMG from Bill Ussery Motors in Coral Gables and took my car into the dealer when i noticed the two rear tires had unusual inside ware. My car has 7000 miles on it and i did not think a one year old car with such low miles would be needing tires so soon. Well to my suprise the dealer Said this is a "LOW PROFILE'' Car and they said this is what I should expect, and would not replace the tires. I am taking further action but was wondering if any one out there has had this same problem!!!!!0
jproc Posts: 135If I get 15k miles out of my tires I consider myself lucky.
I've got a 99 230 which I've had over 4 years and about 35k miles and I am on my 3rd set0
Hi lopz. Edmunds.com has a great article that describes exactly how to calculate lease payments on vehicles. Click on the following link to check it out: Calculate Your Own Lease Payment.
Prices Paid Forums0
Hey trini47. You may have better luck getting a response to your post in one of the following discussions: "Mercedes-Benz SLK" or "Mercedes-Benz SL and SLK (all models)".
Prices Paid Forums0
firstmb Posts: 2First watch your trade in value. By trading in, you can loose easly $2,000 - $5,0000. A dealer can only give you trade in value. They can make it look good on paper, but they do this all day long. Even I learn a new trick each time I look at buying a new car. If they show you more above value than trade in on paper that means you didn't do very well on the buying price. I usually save at least $5,000 on a new car but they always size up the buyer on their knowledge. NEVER EVER talk payment to a dealer. when they ask what you want your payment to be, then your not talking about the total cost. The only good thing about a lease is the users tax depending on your state. Instead of paying all your sales Tax after you purchase a car, you only pay a users tax with ever monthly payment. If you total the car after 30 days then you have only lost one month of users tax not the total cost of the car.
Just keep in mind when a dealer says that they are not making any money on this deal that they are willing to give you, they would not be in business if they were not making any money. Remember, Leases are call "Fleases</".
Sell you call out right. The dealer wants you car so bad that they can avoid delivery cost and lot fee for Taxes. Hope some of this helps.0
marias17 Posts: 1I am trying to get the best deals for leasing an SLK350 2006/2007 ... preferably 27 months .... can anyone help?0
sjl2 Posts: 10Can you please post October lease rates for 2006 MB SLK 280/350 for 24/27 and 36/39 months? Thanks.0
topspin Posts: 7Lease Rates & Residuals – Effective 10/6/06
Add 2% to Residual Value for 12k mi/yr and 3% for 10k mi/yr on all terms for Mercedes
2006 SLK Class 2dr Convertible SLK280 / Compare Instant Lease Quotes
24 mo/15k mi – Residual Value 61% of MSRP – .00405 Base Money Factor Rate
36 mo/15k mi – Residual Value 55% of MSRP – .00370 Base Money Factor Rate
48 mo/15k mi – Residual Value 48% of MSRP – .00370 Base Money Factor Rate
60 mo/15k mi – Residual Value 42% of MSRP – .00370 Base Money Factor Rate
2006 SLK Class 2dr Convertible SLK350 / Compare Instant Lease Quotes
24 mo/15k mi – Residual Value 62% of MSRP – .00405 Base Money Factor Rate
36 mo/15k mi – Residual Value 56% of MSRP – .00370 Base Money Factor Rate
48 mo/15k mi – Residual Value 50% of MSRP – .00370 Base Money Factor Rate
60 mo/15k mi – Residual Value 42% of MSRP – .00370 Base Money Factor Rate
2006 SLK Class 2dr Convertible SLK55 / Compare Instant Lease Quotes
24 mo/15k mi – Residual Value 61% of MSRP – .00405 Base Money Factor Rate
36 mo/15k mi – Residual Value 54% of MSRP – .00370 Base Money Factor Rate
48 mo/15k mi – Residual Value 47% of MSRP – .00370 Base Money Factor Rate
60 mo/15k mi – Residual Value 40% of MSRP – .00370 Base Money Factor Rate0
imshane54 Posts: 5Dear Car Man..... Ha ha....
You helped me a month ago to buy an Infiniti G35. Thank you very much! I now need your help again. I need to buy a Mercedes SLK350 with a premium package II, Run Flats and an ipod int. kit. The MSRP including options looks like 53,900. I have not negotiated the price yet. Can you give me an idea of what a good deal looks like on a 39 month lease with drive offs? I owe you! Thanks again. Your services are very much appreciated!0
oliver9 Posts: 6Hi CarMan
Sorry I can't find sl550 lease question forum. So I posted here. Edmunds posted an attractive financing incentive at 4.9%/4 years for the sl550. I was wondering if you can post the Feb lease rates for sl550.
Thanks for doing this service. This help tremendously.0
toddturner Posts: 8I saw this on Edmunds site, but not at mbusa.com. Does anyone have lease rate / residual info on this?
There may be other leases available. Contact a local dealer for more information.
Start: 03/01/2007 End: 04/02/2007
$499 Monthly Payment Calculate Other Monthly Payments
27 Month Term
$2750 Down Payment
NA Security Deposit
10000 Annual Mileage
Restrictions Lease is based on the 2007 SLK280 equipped with optional Premium 1 package. Dealer may contribute $1,507.88 towards the $499 monthly special lease.
Comments $4,044 is due at signing. Dealer participation may vary. Incentives and Rebates are provided subject to the terms of our Visitor Agreement. Tax, tags and insurance are extra.0
newcar45 Posts: 14If you go to the dealership, the salesman will present this to you. From what was listed, the money factor was .001 and the residual was 66%.
Pretty good right?
Unfortunately, the MSRP of the model listed is pretty rare (non-metallic paint, not an automatic, etc.), and 10k/year will probably be lacking for many people.
I'm curious, should the money factor change if you don't make a down payment or if you increase the annual mileage from 10k to 12k?
And, what should a good monthly price be for a 27 month lease with 12k/year for an SLK280, automatic, metallic paint, Premium 1 and a CD changer (MSRP $49,505?)?0
outie Posts: 42Does anyone have the latest MF and residuals for the 07 models? SLK55 in particular. Thanks.0
lbh2315 Posts: 6Here is the proposed deal, Carman - any advice?
2007 Mercedes-Benz SLK280
Metallic Obsidian Black
7G Auto trans
Premium Pack I
CD changer
AIRSCARF, heated seats
Purchase Price = $46,000
Decap = $1,000
Money factor = .00150
36 months
57% residual
Monthly of $596/mo (incl. tax)
Thoughts? I am also looking at the Audi TT and the Porsche Boxster. This deal seems to beat them hands down.0
I just saw that MBUSA.com is showing a new "Summer Love" sales campaign. Unfortunately, no actual numbers are provided so although the SLK is listed as a car in the sales event...I have no clue how good it truly is...
Does anyone know the Residual and MF for this month??? (36mo/48mo and 15k)
Thanks in advance!0
I just spoke with my local dealership and he confirmed that new rates will be coming on July 15th as the current rates are "horrible". On top of this, there's $3k mfg to dealer cash right now on the SLK 280....Hopefully, I can walk away with a great deal in a week or so...0
Can anyone give me the scoop on how much I will pay for a 24 mo or a 36 mo lease - HEAR their is a $3000 dealer cash incentive and great rates? Can someone post some nubers for 10 to 15K/year at 24 mo or 36 mo? TOTALs?0
Hi- would you mind giving me the scoop on how much I should be paying if I lease in the next 10 days? Looking for some numbers. THANKS
johnboyps Posts: 6Does anyone know if Mercedes has decent leases for used SL's? I am considering leasing a used SL instead of a new one. I don't put many miles on a car and thought leasing a used one might be cheaper on the payments. Does anyone have any input on leasing used? I have always leased new cars.
fx4a4 Posts: 2Hi Car_man,
Can you please provide me with the residuals and money factors for a 350 SLK with amg sport package. looking at 33 month term with 10k per year. What type of dicount off of msrp can i expect?
rking1118 Posts: 3I have a 2004 SL500 with the lease coming due in mid May. Residual is just over $49,000. I love the car and have had virtually NO problems with it. The car has 39,000 miles on it and will be about 7,000 under the amount allowed by the lease (12,000 a year) at lease end. These vehicles are going for around $40,000 at the auction and only a car that has been completely reconditioned is worth close to what my lease end buyout would be. I know this car and have done the maintenance on it, however with 40,000 miles, I will need to replace tires again, do the brake pads and a B service if I keep the car. I have been told that I may be able to negotiate a better buyout from MercedesBenz financial. What should I offer? I would not mind keeping the car, but not at the automatic buyout. I am considering offering $40,000. Is that even realistic? Thanks in advance for any help and guidance.
gforce11 Posts: 225Rking, I would pitch the 40k buyout to MB Financial. They are usually willing to negotiate, specially since models similar to yours are no where near your buyout price. Residuals are generally projections and estimates of what your car might be worth at lease end so I would never pay that price. I know my sister was able to renegotiate her Volvo S40 (I know, not the same car but same idea) at lease end and was able to shave $3000 dollars off the buyout price. You got nothing to lose.0
erichayes Posts: 1Can someone post the 2009 slk lease rates?
I have a 2009 slk 350 on order. it should be coming in within the next month.
I feel a little exposed that i do not know the current residual and money factor offered.
The dealer said they could not tell me until it comes in.0
sparkangelo Posts: 6I'm looking for a short term lease on the slk 2012. What are some quotes that's out there?
10k mi 24 or 27mo lease.0
Hello sparkangelo. Mercedes-Benz Financial's current buy rate lease money factor and residual value for a 24-month lease of a 2012 SLK350 with 10,000 miles per year are .00154 and 68%, respectively for consumers who qualify for its top credit tier.
Use these numbers and negotiate as low a selling price as possible.
Prices Paid: Buying & Leasing Experiences Forum0
georged4 Posts: 34Hi Carman,
Are current Mercedes SLK new car leases for the longer terms available?
The Mercedes dealer in Fort Meyers has offered 8.5% off MSRP for a 2012 SLK. Is that a decent deal? I am considering the lease vs 72 month financing VS a finance with Balloon payment. The salesman discourages balloon but my thinking is that he does better with a lease.
Our plan is to buy the car new and keep it for many years. I know a purchase is the best financially, but I'd like to keep the payment low. I have Tier 1 credit and stable income so am not worried about refinancing in 3-6 years unless of course rates go crazy high. IF that happens I Can always sell since I will probably put $10K down so should have equity.
I can get less than 4% on a 72 month financing from Cap One.0
Hi georged4. One can lease a Mercedes-Benz vehicle for up to 60 months through its captive finance company, but its lease support is only available for up to 48-months.
Prices Paid: Buying & Leasing Experiences Forum0
This discussion has been closed.


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New -Craft MMO Announced, Using Unreal 3
According to the spec sheet, CrimeCraft will allow players to take a strong role in the economic dealings of the world, with the ability to deal in real estate as well as operate a number of types of businesses including shops, factories, and banks. Player can choose to operate on either side of the law. Vogster notes that the game's social system will be "developed" and its combat system "unique," though it does not go into great detail. Several pieces of character artwork were released.
"We are proud to have Vogster Entertainment choose Unreal Engine 3 for what promises to be a truly engaging MMO game." said Epic VP Mark Rein when the license deal was annouced. "We are confident that our technology will help Vogster Entertainment develop an outstanding product, and we look forward to this exciting new relationship. To work with such a talented group of developers in exciting places like Kiev and Moscow is going to be a lot of fun for Epic."
CrimeCraft is currently planned for release in 2008 on PC, PlayStation 3, and Xbox 360.


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Global Metabolomics Market Worth $1.5 Billion by 2017
Jan 11, 2013, 06:30 EST
DALLAS, January 11, 2013 /PRNewswire/ --
The report "Metabolomics (Biomarker Discovery/Metabolite Detection/Metabolite Profiling) Market By Applications (Drug Discovery/Toxicology Assessment/ Diagnosis) and Indications (Oncology/Cardiology/Neurology) - Forecasts from 2012 to 2017", analyses the global metabolomics market by region, applications and indications with five year revenue forecasts. It also identifies the factors driving and restraining the global metabolomics market with analysis of trends, opportunities and challenges.
The market is segmented and the revenue is forecasted on the basis of major regions such as America, Europe, Asia and Rest of the World (ROW) covering the key countries for each region. Further, the market is also segmented and revenues are forecasted on the basis of applications and disease indications.
Browse 11 market data tables and 36 figures spread through136 slidesand in-depth TOC on "Metabolomics (Biomarker Discovery/Metabolite Detection/Metabolite Profiling) Market By Applications (Drug Discovery/Toxicology Assessment/ Diagnosis) and Indications (Oncology/Cardiology/Neurology) -Forecasts from 2012 to 2017"
Early buyers will receive 10% customization on reports.
In the post genomic era, metabolomics is gaining importance as another promising "omic" technology for understanding the biology of various diseases. Rapid advancement has been occurring in prediction, detection, monitoring and understanding of various diseases using metabolomic technologies.
The market for metabolomic data analysis tools and software is increasing at a higher rate. Metabolomics allows pharma companies to stretch their R&D efforts by improving efficiency in target discovery and validation, mode-of-action, and toxicology studies. There has been a significant global growth in biotechnology and pharmaceutical industries in the last decade and the market is expected to have a double-digit growth rate in the coming years.
Biomarker discovery services and increased need for toxicity testing are driving the metabolomics market. Nutraceuticals, plant genomics, nutri-genomics, and systems biology are some high growth and emerging application areas that are expected to drive the global market of metabolomics in coming years. The global market for metabolomics in terms of revenue is estimated to be worth $343 million in 2012 and is expected to reach $1.5 billion by 2017, growing at a CAGR of 35% from 2012 to 2017.
About MarketsandMarkets
MarketsandMarkets is a global market research and consulting company based in the U.S. We publish strategically analyzed market research reports and serve as a business intelligence partner to Fortune 500 companies across the world.
MarketsandMarkets also provides multi-client reports, company profiles, databases, and custom research services. M&M covers thirteen industry verticals, including advanced materials, automotives and transportation, banking and financial services, biotechnology, chemicals, consumer goods, energy and power, food and beverages, industrial automation, medical devices [ http://www.marketsandmarkets.com/medical-device-market-research-11.html ], pharmaceuticals, semiconductor and electronics, and telecommunications and IT.
We at MarketsandMarkets are inspired to help our clients grow by providing apt business insight with our huge market intelligence repository. To know more about us and our reports, please visit our website http://www.marketsandmarkets.com
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text:
What is in this article?:
- Luscious, light desserts
- 5 tips for lighter desserts
If you think the words healthy and dessert simply don't go together, prepare to be delighted and surprised. In these light, easy-to-make desserts, rich-tasting, wholesome ingredients combine wonderfully to please any sweet tooth, without gluten, dairy, or the sugar or fat overload found in many holiday treats.
More About:
If you think the words healthy and dessert simply don't go together, prepare to be delighted and surprised. In these light, easy-to-make desserts, rich-tasting, wholesome ingredients combine wonderfully to please any sweet tooth, without the sugar or fat overload found in many holiday treats. Using luscious but healthy foods such as fresh fruits, inviting spices, rich nuts, subtle sugars, and smart fats, each recipe packs a powerful nutrient punch and satiates sweet cravings—plus they're all gluten- and dairy-free! Enjoy a guilt-free holiday season with these deliciously different desserts.
Green Apple Tart with Vanilla Pecan Crust
Serves 8 / This scrumptious tart strikes a rare balance between rich and not-too-sweet. Prep tips: Fresh vanilla bean adds a decadent element, but you can substitute 1 teaspoon vanilla extract in a pinch. A mandoline makes it easy to slice apples uniformly, but a good sharp knife works too. view recipe
Cinnamon Walnut Cookies
Makes 10 / Hurrying for a holiday treat? Throw all of the ingredients into the food processor and bake up a batch of these amazing little cookies for your next party. Full of fiber-rich dates, walnuts with omega-3s, and delightfully powerful cinnamon, they offer a clean, satisfying taste, sans a post-dessert hangover. view recipe
Rosemary Pecan Cookies
Makes 24 / Rosemary adds a surprisingly sumptuous flavor to these button cookies, while almond flour provides protein and nutrients. They are less sweet than a typical cookie, but highly addictive. Ingredient tip: Grapeseed oil lends a buttery taste. view recipe
Lemon Thyme Mini Muffins
Makes 16 / A sweet and unexpected take on their lemon poppy-seed cousins, these are fabulous with a post-dinner cup of tea. Ingredient tips: When baking, I prefer grapeseed oil for its buttery flavor. If you haven't used coconut flour before, you'll be surprised at how little is called for in this recipe. It's an economical, fiber-rich, and gluten-free flour that yields fluffy baked goods. Look for Bob's Red Mill coconut flour in the baking aisle or gluten-free section of your natural market. view recipe
Creamy Cinnamon Pumpkin Pudding
Serves 6 / This rich and creamy vegan treat goes together in minutes and melts in your mouth. Ingredient tips: Cooking with agar, a vegan jelling agent derived from red algae, creates an almost instant pudding that will wow your holiday guests—food restrictions or none. Yacon, a thick syrup made from the yacon root, is a lower-calorie sweetener that helps with digestion; I use it in recipes as a substitute for molasses. Serving tip: This pudding is great warmed, with a dollop of whipped cream if you're not vegan.
Cranberry Pear Crisp
Serves 8 / Using almond flour—a superfood in disguise—sneaks protein into your favorite treats, while cooking condenses the fruit to create a burst of sweet pear flavor that complements tart cranberry. This colorful crisp is rich, warm, and soothing on a chilly day and is a truly healthy modern classic … though if you're not vegan you may want to add a dollop of cream, vanilla yogurt, or warm coconut milk. Ingredient tip: I use grapeseed oil for its nice, buttery flavor, but another mild oil such as safflower would also work. view recipe


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Each Eucalyptus candle is carefully crafted to bring forth energizing fragrance and glowing light, helping to create a world of possibility in any environment. Our non-metal wick provides a clean, pure burn time of a minimum of 60 hours.
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View the Eucalyptus Collection.
Smells amazing
This is one of my all time favorites! I recommend this scent to all my friends my whole house smells wonderful!!
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I fell in love with your Eucalyptus at the GreenBriar Hotel in WV. The fragrance is absolutely amazing, the candle is out of this world wonderful. I was extremely disappointed when you discontinued the shampoo & conditioner!
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I really love the eucalyptus smell! Its refreshing; calming and a relaxing aroma! I just love it and recommend it for Christmas!
Love Eucalyptus!!!!!!! Best smell ever!!
love this smell!!! There are not very many fragrances that I like. This one hits it out of the park! Every one loves it!!
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Try it, you'll LOVE it!
My most favorite fragrance...there are many more that I love also.
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What we learned: Ohio State Nike
COLUMBUS, Ohio - Rivals.com analyst Brian Perroni breaks down three things we learned from the Nike camp/Elite 11 at Ohio State last weekend.
1. QBs are stronger than we thought
So far on the Elite 11 tour, the quarterback play overall has been a bit underwhelming. There have been a few prospects here and there that have been truly impressive but it has been disappointing as a whole.
However, the last regional event of the year certainly brought out the best. Four of the top seven quarterbacks in the latest rankings were on hand and most of them lived up to their billing. Gunner Kiel, the No. 1-ranked passer, was the most consistent performer of the day. Fellow Rivals250 prospects Jameis Winston and Tyler Matthews were very impressive as well.
In addition to prospects at the top, the depth of the class was shown too. Chad Kelly had a very good outing and, even though he didn't have a chance to show off his running ability, he proved to be a good passer as well. Other prospects such as Sean Maguire and Kentucky commit Patrick Towles certainly impressed too.
Overall, the Columbus Elite 11 was by far the best regional event of the tour. Though the quarterback position is still a bit down in the class of 2012, it helped show that it still has plenty of legitimate top prospects.
2. Midwest defensive linemen have a common flaw
The defensive line position was the most impressive group at the Columbus Nike Football Training Camp. It was not even close when compared with the depth at other spots. However, there was a common theme among nearly all of the top prospects in the group.
Unlike with other regions this year, the top defensive linemen from the Midwest all seem to be on the shorter side. Defensive ends Adolphus Washington and Se'Von Pittman, the two highest-rated linemen at the camp, both could end up as outside linebackers in college. Neither has the ideal height or length to play on the line. Michigan commit Mario Ojemudia is even smaller than the other two.
The defensive tackle position was more of the same. There were quite a few guys with very strong lower bodies that were able to get a good pass rush but they all lacked height.
Danny O'Brien and Sheldon Day are both four-star prospects but neither one is taller than 6-foot-2. They could have trouble stopping the run at the next level when they are playing against much bigger offensive linemen than they see in high school.
3. The class of 2013 looks strong
Though many seniors-to-be were impressive all weekend, it was some class of 2013 prospects that stole the show at times.
At the Elite 11 event, two of the most impressive quarterbacks were current sophomores. Matt Alviti and Michigan commit Shane Morris both held their own with their older counterparts. In fact, Morris won the quarterback MVP award at the camp on Saturday.
Outside linebacker Jaylon Smith, defensive end Taco Charlton and cornerback Cameron Burrows all had their position coaches raving on Saturday. Smith actually took home linebacker MVP honors ahead of several well-known juniors including Michigan commit James Ross. Running back Berkley Edwards, the younger brother of NFL wide receiver Braylon Edwards, showed flashes of brilliance as well.
Overall, if the Elite 11 and Nike Camps are any indication, next year should be another strong one across the Midwest.


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Erection Problems: Questions Your Doctor May AskSkip to the navigation
Topic Overview
Your doctor may ask questions about the type of erection problem (erectile dysfunction) you have. Examples include:
- Have you started taking any new medicines recently?
- Do you feel depressed or have a low mood or trouble sleeping?
- Are you having any difficulty or stress in your relationship or marriage?
- Did the erection problem start suddenly?
- How long have you been having erection problems?
- When do you have erections, what are they like, and how long do they last?
- What kind of erections do you have when masturbating?
- Do you have erections in the morning or during the night?
- Have you noticed a change in your desire or sexual interest?
- Have you noticed changes in your orgasms or ejaculation?
- Have you ever had any damage to your pelvic area (including surgery or radiation)?
- Do you have heart disease, vascular disease, or diabetes? Have you ever had a stroke?
- Are you having tremors, large changes in how much you weigh, diarrhea or constipation, or are you suddenly very sensitive to hot or cold temperatures?
- Do you have headaches or problems with your peripheral vision?
- Do you smoke cigarettes?
- Do you drink alcohol? If yes, how much?
- Do you have burning when you urinate or blood in your urine?
- What expectations and motivations affect both you and your partner?
Related Information
ByHealthwise Staff
Primary Medical Reviewer E. Gregory Thompson, MD - Internal Medicine
Specialist Medical Reviewer Christopher G. Wood, MD, FACS - Urology, Oncology
Current as ofMarch 14, 2017
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Current as of: March 14, 2017
Author: Healthwise Staff
Medical Review: E. Gregory Thompson, MD - Internal Medicine & Christopher G. Wood, MD, FACS - Urology, Oncology
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Pegasus is a manufacturer of plumbing products that add a touch of luxury to every home. Their range of products includes faucets, sinks, toilets, vanities, bath hardware, bath storage, showerheads and sinks. Pegasus faucets are renowned for their smooth finish and durability. All faucets manufactured by Pegasus feature a mix of beautiful finish and contemporary styling.
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Look closely at any Pegasus product and you'll see how their high standards are carried through every detail. You see it in the rich luster of their finishes. You feel it in the weight of our Roman Tub faucets. You'll notice it in extra touches like how our tub spouts come with decorative escutcheons, or how our shower faucets come with uniquely styled showerheads.
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It's a common sight during the Christmas season to see children lined up, waiting for a picture with Santa Claus.
It's a common sight during the Christmas season to see children lined up, waiting for a picture with Santa Claus.
However, as the camera snapped pictures of Santa at Crowder College on Thursday, it wasn't children climbing up on his lap, for the most part, but his four-legged friends instead.
The Crowder Veterinary Technology Club hosted their first Pet Photos with Santa event from 3 to 7 p.m. in the Williams Agriculture Building.
A Crowder photography student took the pictures, and photo packages were available, starting at $15.
Jay Wilkins, agriculture division chair, served as Santa for the photo shoot.
Crowder student and Veterinary Technology club president Steffanie Stevens said proceeds from the photo packages will help fund an upcoming trip for the club.
"There's a conference in Kansas City and it helps pay for our hotel rooms and registration," Stevens said.
Though Shawna Estep, veterinary technology instructor, said she had participated in similar events in the past, the Crowder fundraiser was Stevens' idea.
"I was just looking online at different fundraisers that techs did, so I thought this would be a great idea for Crowder since we've never done it before," Stevens said.
Estep said the response to the inaugural event had been positive, with 15 appointments in the books at the start of Thursday's photo session.
Among the furry friends posing for a photo on Santa's lap were Dirty, a papillon, Sadie, a pit bull and Cooper, a golden retriever.
Robin Wetzel, a member of the Crowder Veterinary Technology club, also brought her family pet, a three-year-old pomeranian named Reggie, for his picture with Santa Claus.
"The semester is coming to a close and it's just something fun to end the semester," Wetzel said of the event.


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EARTHQUAKE STRIKES: An 8.6-magnitude earthquake and an 8.2-aftershock hit off Indonesia's western coast Wednesday but did not cause a major tsunami.
WHY NOT? These two quakes were strike-slip quakes, which cause a horizontal tearing movement that does not displace the seabed, causing vibrations in the sea instead.
MEGA-THRUST: The tsunami that devastated Japan last year and the 2004 tsunami off Indonesia were mega-thrust earthquakes. They cause the seabed to heave vertically, dispersing large volumes of water.
MAGNITUDE: The magnitudes of Wednesday's quakes were smaller. Japan's temblor was 9.0-magnitude, about four times more powerful than Wednesday's first quake. The 9.1-magnitude quake in 2004, which triggered an Indian Ocean tsunami that killed 230,000 people, was five times more powerful.


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La Belleza Pura Mochila Bag
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La Belleza Pura Mochila Bag
Every one of our Mochila Bags is 100% cotton and handcrafted by the women of the Wayuu Tribe of La Guajira, Colombia. The distinct patterns on the bags are unique to this tribe and every Mochila Bag is one of a kind. Mahayulu is committed to fair business practices, and through your purchases, we aim to improve the livelihoods of the Wayuu people by providing them positive work and compensating them at an above-market rate for their beautiful bags. Thank you for your support in preserving the rich cultural traditions of Colombia.
- measures 10" W x 11" H
- 100% cotton
- one of a kind
- handmade
- $10 of your purchase goes to the Aguayuda Foundation to bring clean water to the Wayuu
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