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(photo courtesy of FtLauderdaleSun)
6 more weeks of winter? We hope so, but we'll find out tomorrow! In the meantime, see how Punxsutawney Phil warms up in Greater Fort Lauderdale: sunny.org/groundhog!
Year-to-date 2015 hotel occupancy is up 1.2% over 2014 and ADR is up 6.3% over 2014 (both the highest year-end ever). RevPar is up 7.6% over 2014.
|December 2015
|December 2014
|% Change
|December 2015
|December 2014
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The Greater Fort Lauderdale Convention & Visitors Bureau brought the sunshine to London in January. A team of "Hello Sunnys" greeted winter-weary pedestrians with beach-ready giveaways at Liverpool Street Station, South Bank and One New Change on Thursday, January 21, spreading warmth and cheer from Broward County's 23 miles of Blue Wave certified beaches. One lucky UK winner will receive a 7-night getaway to Greater Fort Lauderdale for two including round-trip airfare on British Airways. A fleet of 25 Hello Sunny branded taxicabs have been driving around London from Nov through Feb, complete with seat back video and branded taxi receipts.
Nicki Grossman hit the airwaves for 28 radio segments supported by celebrity psychologist Geoff Beattie, to discuss how a holiday in Greater Fort Lauderdale could help to alleviate the winter blues. The interviews aired throughout the UK and even went global through the British Armed Forces network. Nicki also hosted a well-attended media breakfast reception where journalists learned to make Florida style 'sunny marys.'
In addition to the media and consumer activities, the Hills Balfour public relations team also organized multiple meetings for Richard Gray during his time in London including leading UK transgender celebrities Kellie Maloney and Rebecca Root and with reality TV star Charlie King.
For the first time, the Food Network & Cooking Channel South Beach Wine & Food Festival presented by FOOD & WINE (SOBEWFF®) heads up the coast to host the inaugural Taste Fort Lauderdale event series during the 15th annual festival, February 24-28, 2016. The five-day Taste Fort Lauderdale series will kick off with a Seaside Eats event at the Bonnet House Museum & Gardens, hosted by Chef Robert Irvine, followed by events at Casa D'Angelo Ristorante featuring Gabriele Corcos and Debi Mazar, S3 featuring Todd English, Valentino Cucina Italiana featuring Marc Vetri, Kuro featuring Justin Warner, and end with a Bloody Mary Brunch at The Ritz-Carlton, Fort Lauderdale, hosted by the cast of Chopped. Organizers are thrilled with the response as events are selling out quickly! Visit sunny.org/tastefortlauderdale for more info.
Greater Fort Lauderdale has been named a Top 10 Family Destination in KAYAK's 2016 Travel Hacker Guide, an interactive resource full of data-driven insights and hacks. The 2016 Guide was curated by KAYAK's team of data scientists and travel experts who analyzed the site's more than one billion annual searches to identify key insights on where to go and when to book to make travel planning easier. Click here to see!
Last month, Anna Levin, our Ambassador of Bliss, along with Sheri Benkendorf from The Ritz-Carlton, Fort Lauderdale, attended the Martha Stewart's Wedding Party in NYC, showcasing Greater Fort Lauderdale as the perfect wedding destination to more than 900 brides in attendance.
To attract visitors looking for romance, we invite you to create special offers like spa treatments for two, wine pairings or other creative ideas. We are featuring your offers on sunny.org/valentine and our social media outlets. Submit your offers under your partner login at sunny.org/partneraccess. If you do not know your partner login, contact Michelle email@example.com. When creating your coupons for your special offers, be sure to select the Valentine Deal category. If you have any questions, feel free to contact Justin firstname.lastname@example.com.
Sports Development welcomes more than 25,000 athletes, coaches, and families to Greater Fort Lauderdale in February, attending events such as: the USA vs Chile Rugby Tournament at Central Broward Regional Park, the A1A Marathon and Half Marathon and Expo in Fort Lauderdale, the International Water Polo Tournament in Coral Springs, the Fort Lauderdale International Billfish Tournament, the SAHOF (Statewide Amateur Hockey of FL) Hockey Championships at the ICEDEN in Coral Springs, and the Weston Cup Soccer Tournament.
In January, Fernando Harb, Erick Garnica and Caitlan Etchevers attended Florida Huddle in Tampa, and met with hundreds of domestic and international buyers. Caitlan Etchevers attended AAA travel marketplace in Columbus, OH with more than 18,000 consumers and travel professionals stopping by the booth. Caitlan also was inducted as a new Rotarian with the Fort Lauderdale Cypress Creek club, and joined local travel agents for an educational afternoon at the NACTA South Florida at their monthly meeting at Flamingo Gardens. Justin Flippen joined other members of the CVB, including Albert Tucker, at the grand opening of the Lauderhill Performing Arts Center.
The GFLCVB UK team had a busy start to 2016 supporting the efforts of the CVB bringing some much needed Greater Fort Lauderdale sunshine to London. The team coordinated with Expedia on Magic FM for giveaways, activations at London Liverpool Street Station, South Bank and One New Change, along with hosting a media breakfast where journalists learned to make Florida style 'sunny marys' and organized 28 radio interviews for Nicki Grossman, supported by celebrity psychologist Geoff Beattie, to discuss how a holiday in Greater Fort Lauderdale could help to alleviate the winter blues. The PR team also organized multiple meetings for Richard Gray during his time in London including leading UK transgender celebrities Kellie Maloney and Rebecca Root and with reality TV star Charlie King.
Greater Fort Lauderdale hosted the 2016 Urban League Association of Executives conference in January. Angella Lopez continues to work on booking the 2017 and 2018 programs. Greater Fort Lauderdale will host the National Organization of Black Law Enforcement Executives Symposium (NOBLE) February 11-14, which will welcome leadership from all of the law enforcement agencies such as Homeland Security, FBI, and CIA. This will be the precursor of the National Conference coming to GFL in 2018. Albert Tucker also attended the President Barack Obama: The Exhibition at the Miramar Cultural Center last month.
Greater Fort Lauderdale celebrates its rich history and spirit of diversity during Black History Month. Click here to read about important landmarks and groups that are central to Broward's past and present.
Total passenger traffic for December 2015 was 2,599,525, up 7.8% over December 2014. Domestic traffic increased by 8.1% and international traffic was 7.8%. It was also the 21st consecutive month of growth in total passengers. Total passenger traffic for 2015 was 26,941,511 up 9.3% over 2014. Domestic traffic was up 7.3% and international traffic increased by 18.0%. Airports Council International (ACI) data for the 12 months ending November 2015 listed FLL as the 4th fastest growing airport with total traffic up 9.4%. Air carrier operations for the year were 239,940 up 7.9% over 2014. General Aviation was 38,062, up 5.7%. Total aircraft operations were 278,000, up 7.6%. Calendar year 2015 vs. 2014 flight and destination comparison include: six more daily international departures in 2015 (now at 66); three more international destinations (now at 50); sixteen more daily domestic departures (now at 236); nine more domestic destinations (now at 75); twenty two more daily total departures (302); and twelve more destinations (now at 125).
New airlines serving FLL for 2015 included Dynamic Airways to Caracas, Venezuela and Cape Air to Bimini. New service for 2015 international and domestic Caribbean service includes: JetBlue to Quito, Ecuador in February 2016, Barbados in April 2016, and Aguadilla (Puerto Rico) in May 2016. New or upcoming domestic service includes: JetBlue to Syracuse (seasonal service) in January 2016, Nashville in May 2016, and San Diego in June 2016; Spirit to Philadelphia in April 2016. FLL now offers Mobile Passport Control. This free downloadable app allows eligible travelers to submit their passport information and customs declaration form to CBP via a smartphone or tablet app prior to arrival cutting wait times and allowing faster processing.
Congrats to Richard Gray and GFLCVB for receiving the eTN Honest Travel Award from eTurboNews.com. Click here to read about it. Richard Gray participated in the UK Hello Sunny Activation in London Jan 18-22 meeting with key media as well as transgender celebrities Rebecca Root, the star of Where Boy Meets Girl; and Kellie Maloney, the boxing manager who recently became a transgender woman, both interested in promoting GFL's Southern Comfort Transgender Conference in the UK. In January, Passport Magazine had a swim wear cover shoot in Fort Lauderdale, the first transgender female to male swimwear cover by a national magazine. In February, Richard will attend Visit Florida's New York press reception, meeting with key LGBT media. GFL will host the Bears of All Colors Event, Feb 25-29 with the Ramada Oakland Park Inn as the host hotel. GFL will also host more than 10,000 transgender, lesbian and gays visitors on three sell out cruises from Port Everglades in February. And gay sports is very strong this month with gay rugby, flag football, tennis and volleyball all hosting events here.
Noelle Stevenson attended Sundance Film Festival, hosting a Kreate Films/CVB OFME event with key film distributors in attendance focusing on film projects shot in Broward County. In addition key industry leaders attended this annual film festival including daily AFCI events. Paramount Picture's Baywatch feature film sets shop in Broward County with the remake of the renowned TV series. Cast includes Zac Efron, Dwayne Johnson, Alexandra Daddario, Priyanka Chopra, Kelly Rohrbach, Ilfenesh Hadera, and Jon Bass.
Film Permits were issued for the following productions in January 2016: TV Series: HBO's Ballers; I Am Jazz – Season 2; Par 3. TV Commercials: AutoNation; Corona; DeliChoc; Meli Orthopedic; Seamless-Altisource; Spies Travel; We Florida Financial. Still Photography: Balfour; Belk; Bon Prix; C&A; Canadian Tire; Falcon 2000 at Sunset; FEIBA; Roberta Roller Rabbit; Tether; The Children's Group; Toys R Us; Valentine's Day Minis. Telenovelas: La Trailera. Documentaries: Vermisst (Missing); Visit Florida Tudou Video. TV Movie or Special: Shamrock vs. Gracie: The Road to Revenge. Industrial: GFLCVB Delegates. Music Video: Vespers Nine – Yes You. PSA: Travel Centers of America – Tips. Web: Humira; KidVision VPK – Yoga in the Park. Other: Broward College LINCS Program; Color Splash Video; Que Noche con Angelica y Raul.
Groups meeting in February will generate more than $32 million to Broward County. Groups include:
Feb 1-9: PRI-MED South 2016 (4000 attendees)
Feb 3-7: Ricky Tims Super Quilt Seminars (550 attendees)
Feb 4-11: 2016 ISET – Int'l Symposium on Endovascular Therapy (727 attendees)
Feb 5-9: Rugger Convergence 2016 (600 attendees)
Feb 6-10: National Association of Chain Drug Stores Regional Chain Conference 2016 (270 attendees)
Feb 7-10: NICSA 2016 Annual Conference (350 attendees)
Feb 7-14: 2016 MoreDirect Solutions Summit Meeting (500 attendees)
Feb 10-14: 2016 Winter CEO Symposium and Executive Board Meeting (300 attendees)
Feb 11-16: NLMC 2016 (250 attendees)
Feb 12-17: Florida Sunshine Cup 2016 (700 attendees)
Feb 12-17: 2016 Clay Court Classic (500 attendees)
Feb 13-21: 2016 HCV Launch (530 attendees)
Feb 17-24: ABRF 2016 Annual Meeting (450 attendees)
Feb 17-27: 2016 Celgene Corporation National Sales Meeting (965 attendees)
Feb 19-27: Nielsen US Media Summit (350 attendees)
Feb 21-Mar 4: BMO Capital Markets 2016 Global Metals & Mining Conference (1000 attendees)
Feb 25-Mar 6: 2016 Workforce Development Conference (1050 attendees)
Feb 28-Mar 6: BISA 2016 Annual Meeting (500 attendees)
Feb 29-Mar 5: American Glaucoma Society 2016 Annual Meeting (320 attendees)
The Boarding (formerly the Cheese Culture) recently opened on Las Olas Blvd featuring artisan cheeses, charcuterie & tapas. The Casino @ Dania Beach reopened after a complete renovation with 900 Las Vegas-style slot machines, a 24-table card room, nationally known recording artists and comedians, a simulcast lounge and sports bar, multiple dining options and live Jai-Alai. Paddle Lodge launched a service transporting your watercraft (kayaks and/or SUP) to remote areas within Broward County providing a different way to see the local waterfront scene. The free shuttle to Deerfield Island Park now leaves from Pioneer Park as the original site undergoes upgrades. The Lauderhill Performing Arts Center officially joined the arts community with a ribbon cutting and free performances last month.
The Water Taxi expanded routes and the number of stops, particularly in Hollywood including:
Vote for two Fort Lauderdale eateries on USA Today's Favorite Airport Grab-And-Go Dining List: Shula Burger, located in Terminal 1 and in Terminal 3 Food Network Kitchen. Click here to vote!
Rodeway Inn & Suites - Fort Lauderdale Airport & Cruise Port, a budget-friendly, full-service Fort Lauderdale hotel near Port Everglades Cruise Port and near FLL, recently was named the top hotel destination for cruise passengers by the Port Everglades Cruise Survey study, commissioned by Broward County's Port Everglades Department. Read more here.
The Publix Fort Lauderdale A1A Marathon & Half Marathon invites you to participate in the 10th annual running of the event on Feb 14. Anyone interested can register at A1AMarathon.com.
Does your hotel, restaurant, attraction or organization have a visitor-friendly or tourist-oriented event you'd like to see up on Sunny.org? If so, event submission is just a click away! Simply visit www.sunny.org/submit to input the details of your event, including location, dates, times, admission cost (if any), website, and event description. Be sure to select the applicable category for your event and also include and upload a high resolution picture for your event or a photo of the venue at which your event is taking place. Your event submission will then be reviewed, and once approved it will be immediately placed up on our online events calendar for all to see. Questions? Contact Justin email@example.com.
Through Feb 7: Violet, Broward Center for the Performing Arts
Through Feb 29: President Barrack Obama: The Exhibition, Miramar Cultural Center
Through Feb 7: The Book of Mormon, The Broward Center for the Performing Arts
Feb 1: The Zukerman Trio, The Broward Center for the Performing Arts
Feb 2: Groundhog Day on Hollywood Beach!
Feb 4: Detroit Red Wings vs Florida Panthers, BB&T Center
Feb 4: Under the Streetlamp, Parker Playhouse
Feb 5-6: Pinkalicious The Musical, Broward Center for the Performing Arts
Feb 5: Black Violin, Parker Playhouse
Feb 5-6: Casablanca, Broward Center for the Performing Arts
Feb 5-7 Seminole Tribal Fair and Pow Wow, Hard Rock Live
Feb 5: Barry Manilow, BB&T Center
Feb 6: Pittsburgh Penguins vs Florida Panthers, BB&T Center
Feb 6: 16th Annual Black History and Dr. Martin Luther King, Jr. Celebration, Lauderhill Performing Arts Center
Feb 6: Chillounge Night, Huizenga Plaza, downtown Fort Lauderdale
Feb 7: Mardi Gras, History Museum of Fort Lauderdale
Feb 9: Diana Ross, Hard Rock Live
Feb 10: Delfeayo Marsalis Quartet - Last Southern Gentlemen Tour, Broward Center for the Performing Arts
Feb 11-13: Florida Grand Opera presents Norma, Broward Center for the Performing Arts
Feb 11: Hillsong United, BB&T Center
Feb 12: St. Louis Blues vs Florida Panthers, BB&T Center
Feb 13: Nashville Predators vs Florida Panthers, BB&T Center
Feb 13-Mar 20: Florida Renaissance Festival, Quiet Waters Park
Feb 13: Be My Jazzy Valentine, Lauderhill Performing Arts Center
Feb 13-14: Andrea Bocelli, BB&T Center
Feb 14: A1A Marathon, Fort Lauderdale
Feb 15: Pittsburgh Penguins vs Florida Panthers, BB&T Center
Feb 16: Bruce Springsteen, BB&T Center
Feb 18: San Jose Sharks vs Florida Panthers, BB&T Center
Feb 19: Michael Flatley's Lord of the Dance: Dangerous Games, BB&T Center
Feb 20: Winnipeg Jets vs Florida Panthers, BB&T Center
Feb 20: Pompano Beach Heritage Music & Arts Festival
Feb 20-21: Miami City Ballet - Program III, Broward Center for the Performing Arts
Feb 20: Festival Foodie Feud, Festival Flea Market
Feb 24: Iron Maiden, BB&T Center
Feb 24: Experience Hendrix, Hard Rock Live
Feb 24-28: South Beach Food & Wine Festival: Taste Fort Lauderdale Series
Feb 25: Arizona Coyotes vs Florida Panthers, BB&T Center
Feb 26: Fall Out Boy, Hard Rock Live
Feb 26: Disney Live! Mickey and Minnie's Doorway to Magic, BB&T Center
Feb 27: Jeff Dunham, BB&T Center
Feb 27: The Beach Boys, Hard Rock Live
Check out our team in action at various events and functions around the world. Click here to see.
Best wishes,
Nicki E. Grossman


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You just never know when rain will strike. One minute the sun will be shining and the next minute storm clouds are brewing! That's where this trusty Red Ladybug Umbrella comes in handy! This smiley ladybug featured on this unique umbrella would be more than happy to shield you from the rain. And when you can stay dry with a smile, your day is sure to be all the better!
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Should College be Free in the U.S.? International Perspectives
DanBrownPublished: October 13, 2016Updated: October 17, 2016
Published: October 13, 2016Updated: October 17, 2016
These video responses come exclusively from PogoTribers OUTSIDE of the United States, sharing their thoughts on how we educate young people in the US, and globally. What say you!? Leave a comment!
Simon's Response (Colombia):
Jeppe Muk's Response (Denmark):


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Clinical Team
Rachel Griffin, PA-C
Physician Assistant
"Hey Clinic provides the resources and experience of a large medical facility, but the compassion and service for a personalized experience."
Rachel grew up in Greensboro, NC. She received her Bachelor of Science in Community Health Education and her Bachelor of Arts in Spanish from The University of North Carolina, Wilmington in 2009. Following graduation, she worked in Wilmington with a nonprofit organization doing health education. She attended Wake Forest University Physician Assistant Program and received her Master's degree in Medical Science. Outside of work she enjoys baking and being active outdoors with her husband, her daughter and their dog, Riley.
Kristina Stanson, PA-C
Physician Assistant
"I love that the Hey Clinic strives to educate our patients and equip them with knowledge that enables them to become active members of their own medical care team."
Kristina was born and raised in Raleigh, NC. She received her Bachelor of Science in Biology and Psychology from the University of North Carolina at Chapel Hill. She earned her Master of Medical Science from Wake Forest University School of Medicine. In her free time, she enjoys spending time with family and friends and cheering for the Tar Heels.
KC Wheeler, C.P.O.
Certified Prosthetist-Orthotist
KC grew up in Peekskill, NY where she always had a love of science and medicine.
She attended Pace University in Pleasantville, NY where she received her Bachelor of Science degree in Biology. She then spent 5 years in Dallas TX, where she attended the University of Texas Southwestern Medical Center at Dallas. There she received a second Bachelor of Science degree in Prosthetics and Orthotics. KC completed her residencies for both disciplines at the UNC Hospital Brace Shop in Chapel Hill, NC. She achieved certification in both Prosthetics and Orthotics in 2001. She currently lives in Fuquay-Varina and enjoys spending time with her husband and two boys.
Allie Gordon
Medical Assistant
"It has been a joy to work with a team that truly loves what they do and is so focused on compassionate patient care."
Allie graduated from Fuquay Varina High School and the University of North Carolina at Chapel Hill with a degree in Biology and minor in Chemistry. She has experience in EMS and loves traveling and spending time with her husband.
AJ Jackoby
Medical Assistant
" I love the compassionate patient care the Hey Clinic provides, along with the initiative to educate people that will empower them to be a part of the their medical team."
Grew up in Upper Sandusky OH and graduated from The University of Toledo with a bachelors of Science of Athletic Training. I worked at a high school in Michigan as well as for the Toledo Club Hockey team the following year. Recently worked at OSNC where I was an Athletic Training Resident along with being an Athletic Trainer for the Carolina Mudcats.
Administrative Team
Office Manager
"I enjoy working with a team that really cares about what we do. We want our practice to reflect the genuine desire to serve in any aspect. "
Sarah grew up in Durham, NC and graduated from North Carolina State University with a degree in Biochemistry with a minor in Business Management. She started at Hey Clinic as an intern, and has cross covered many roles at our clinic which makes her an excellent office manager. Her focus on team communication, and quality goes right in line with Dr. Hey's practice style. She enjoys the family dynamic that we've built at the Hey Clinic and being a facilitator to allow the clinic to run smoothly. Outside of the clinic, she enjoys spending time with her husband, cooking and serving church.
Billing Manager
"My favorite part of working with Hey Clinic is getting to be apart of a team that strives for top-notch service at every encounter. "
Jennifer grew up in Salt Lake City, UT and moved to North Carolina in 2004. Her background is in accounting, banking, and finance. Her degree is from Salt Lake City College. She has been fortunate to have worked with several doctors over the years and to now offer our patients the benefit of over a decade of experience in medical billing and coding. In her downtime she loves to travel, read, garden, and spend time with her husband and daughteic is my first medical office, and I couldn't be happier anywhere else. Dr. Hey gets to know and truly cares about his patients, and the rest of the team is happy to follow his lead. I'm learning how to blend business and compassion from the best people."
"I love the interactive nature of having our own electronic medical records system. I like to be able to respond to needs in real time! "
Austin grew up in Durham, NC and graduated from UNC – Chapel Hill. He joined Hey Clinic as our programmer and is pro-active in solving issues with workflow or manipulation of the data we collect for each guest we see. He is a great addition to our clinic family and is great at understanding a co-workers requests and translating them into a technical solution. When he is not helping maintain and improve our systems he enjoys camping and canoeing for vacations.
Director of Education and Research
"I love being part of a system that helped my son. I love helping patients with practical advice and educating area providers on how we can help co-care for their patients."
She has a degree in Marketing and Advertising. Since raising her children, she has held several positions in media both as Publisher of a local newspaper and in advertising sales. Wendy is able to bring a unique perspective to our office as she is a Mom of one of our patients. This helps us to consider the patient's and caregiver's needs when creating systems for our office. She handles other responsibilities as well such as education of local providers regarding spinal deformity and representing our office at conferences. She lives in Willow Springs and enjoys spending time with her husband and 3 children.
Scoliosis & Spine Surgery
3320 Wake Forest Road, Suite 450
Raleigh, NC 27609
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it's my birthday!
|{magnolia cake from husband}
while i transition to a new decade, makeuplovesme has transitioned this past week to a new layout. i'm loving how authentic it is to my original design, yet more simplistic and intuitive. as i continue to grow and refine my life in so many ways it's fun to watch my blog make similar transitions.
this past weekend i celebrated this milestone birthday by having friends over for cocktails (from the domestic mixologist). it was a low-key early summer night spent on the roof deck. i envisioned many possible ways i'd spend today, my actual birthday. but ultimately i decided to go with the basics, shopping and introspection. i started the day with a very rainy walk in the park, and now i'm headed downtown to soho to update my wardrobe. i'll end the day by meeting up with my husband for a thai street food style dinner at spice market.


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Valley (Gei ben Hinnom) outside the western wall of Jerusalem, mentioned in the Bible (Jos. 15.8, 18.16; 2 Kgs. 23.10; Jer. 7.31; Neh. 11.30) as a valley through which ran ...
Subjects: Judaism and Jewish Studies.
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It is no strange to everyone now to back to old time - big size phone. Samsung Galaxy Note series aiming to be Phablet device packed with huge screen officially released new successor, know as Samsung Galaxy Note II. Of course beside being big size in screen, the Stylus or known as S Pen is add on point for this Phablet.
I am lucky enough to get a review set from Nuffnang and Samsung. I will separate few parts of the review so that I could stress it out some important point and my own opinion on the Samsung Galaxy Note II.
Let's start with the specification. Samsung Galaxy Note II is packed with 5.5 inch display with Super AMOLED screen and 720 x 1280 pixel. It running the Samsung latest quad core processor - 1.6 GHz quad-core Cortex-A9 CPU (Exynos 4412 Quad chipset), Mali-400MP GPU and 2GB of RAM for smooth multitask sailing. It come with variant storage size which are 16/32/64GB internal storage with expandable microSD slot.
Of coz on the back it has same 8 MP camera unit with Samsung Galaxy S III. So we are expecting the same image processing and quality. Front facing camera is 1.9MP. Samsung slapped a huge battery on the Note II, which is 3100 mAh and still manage to maintain the slim profile, 9.4mm. Well, not the best. Really because Motorola DROID RAZR MAXX HD has 3300 mAh with 9.3mm thickness.
Other than that, Samsung Galaxy Note II come with removable battery on the back. It also used micro Sim like most of the smart phones now days. Not to mention it has built in NFC which allowed Android Beam and S Beam.
Overall, I felt that Samsung Galaxy Note II is too big for my palm. I do mentioned before I already dislike the size on Samsung Galaxy S III. My small palm just perfect to fit in 3.5-4.3 inch smart phone. Here some comparison of size with my current Asus Padfone.
The difference position of BACK and OPTION button pretty frustrated as well.
Another thing I dislike was the back casing. Well it just make the phone easily get scratches and also finger print magnet. I will appreciated the nice metal brush texture if only the plastic layer is removed.
Alright that's all my first impression on Samsung Galaxy Note II. I am not touching on the software part yet which I gonna cover it on the next review. Here some bonus images comparison between Samsung Galaxy Note and Note II.
Do check out my first hands on video k?
For those Samsung Galaxy Note II user, tell me do you like your current phone? ;)


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About Duane Morris Institute
Payment Options
Flexible Payment Options
Dedicated to making quality education from world-class faculty accessible to a wide range of professionals, DMi offers flexible options for payment and participation in our webinars, seminars, and events. See attached pricing chart.
1.5 Hours - $125.00
$112.50 for Non-Profits
1 Hour - $85.00
$76.50 for Non-Profits
Half Day (2.5 Hours) - $150.00
$135.00 for Non-Profits
4-4.5 hrs (Until 1:30 or 2:00 pm) - $175.00
$157.50 for Non-Profits
Full Day (5.5 Hours) - $200.00
$180.00 for Non-Profits
Non-Profits receive a 10% Discount
off full-price
off full-price
Subscription Program
Organizations can pay a flat fee and receive a discounted block of seminars
Gold Level
24 Classes
$1800 for Non-Profits
Silver Level
12 Classes
$1000 for Non-Profits
Gold Level
12 Webinars
$765 for Non-Profits
Silver Level
6 Webinars
$430 for Non-Profits
Bronze Level
3 Webinars
$205 for Non-Profits
Payment can be made by check or credit cards.
For more information on payment options, subscriptions or financial assistance,
please contact Deborah Margulies (email@example.com or 215.979.1957)
please contact Deborah Margulies (email@example.com or 215.979.1957)
On-Site Trainings
Tailored to your business needs, DMi's On-Site Trainings are interactive, engaging, and focused on solving real business problems.Request Info
I love the fact that you approach things from a business standpoint rather than a theoretical or hypothetical standpoint. The combination of knowledge and personality cannot be beat.
- HR Manager


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Recently, a Canadian tribunal overturned the requirement that a woman could not wear the niqab during a ceremony when new Canadians become citizens. The court ruled that it was sufficient that the woman showed her face to the judge in private before the public ceremony and then could participate in the ceremony while wearing her niqab.
Related Posts
Now, the Conservative Party of Canada swears it will appeal the decision to the Supreme Court, and if elected will pass a law in parliament banning the wearing of the niqab during the citizenship ceremony during the first 100 days of a new mandate. Likewise, the Bloc Quebecois is running television ads in Quebec demonizing the front-leading New Democratic Party with a graphic of black oil oozing out of a container and pooling into the shape of a niqab. Enough to drive a separatist to shout out "Hostie, Tabarnac" (swear words in Quebec referring to sacraments of the Catholic mass).
Yet, as Elizabeth May, leader of the Green Party, so eloquently pointed out during the leaders debate in French, "what does a woman wearing the niqab have to do with the economy, climate change, or health care"? Well Elizabeth, if you would permit me to respond to your rhetorical question: nothing, zero, zip, nada, sweet fuck all!!!
Really what it comes down to is two political parties that are trying to avoid a disaster and are appealing to their voting base of old stock Canadians of either English or French heritage, you know the two founding peoples, that just happen to be mildly to overwhelmingly xenophobic.
Their chains are being yanked to bring them to the polls because as it stands now, if many of the party faithful decide to stay home on election day, the Conservatives will not only lose their majority government but will register their worst share of the popular vote since Confederation, and the Bloc stands to be wiped off altogether from the electoral map.
Fortunately, such fear mongering doesn't work with the vast majority of Canadians that have come to accept that Canada is a multicultural nation that respects the rights of each of its citizens regardless of the color of their skin, their gender, their age, their sexual orientation, and yes, their religious beliefs.
Oh Canada, I stand on guard for thee!!!


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Lawn care company, Fairway Lawn Services, accounces a new service and marketing campaign in Atlanta, Georgia.
Online PR News – 05-February-2011 – – Fairway Lawn Services, an Atlanta-based service enterprise, announced the selection of Panorama Press as their marketing partner. Fairway Lawn Services helps families within the Atlanta Community dealing with lawn related services, weed control, fertilization, bush and shrub, insect control and lawn mowing needs.
Fairway Lawn Services is a home service company that acts as a guide in the sea of choices by providing assessments, analysis of options, and guidance throughout the selection process of Lawn Care Services.
The website, www.LawnCareServiceAtlantaGA.com, features information on the benefits of using Fairway Lawn Services. The Fairway Lawn Services Atlanta campaign will be a multimedia operation that will include the website plus ad placements in various internet media outlets, supported by online promotions including the blog and other online strategies to help inform the public, businesses and community groups about their options to improve the selection process for Lawn Care services, mowing, fertilization, weed control, and pest control.
Fairway Lawn Services is a member of TCAGA - the Turf Care Association of GA. This is a consistent source of information and training that is specific to the Lawn Care industry. Fairway Lawn Services belongs to the Turf Care Association of Georgia. Fairway Lawn Services believes in continuing education to sharpen skills.
Fairway Lawn Services accomplishes this by attending trade shows and seminars to keep up with change and the newest state-of-the-art product lines, taking continuing education classes, receiving certifications in specialized and general knowledge areas and awards for leadership in the industry. An incentive program is offered for employees to increase learning, and an apprentice program to train up new talent.
Fairway Lawn Services is located at 908 River Stone Way, Woodstock 30188. You can contact Tommy Campagna by dialing 404-592-0584 or emailing him at firstname.lastname@example.com.
Fairway Lawn Services provides a no-cost process to help families through the needs and selection aspects of the Lawn Care selection process.
• Lawn Fertilization
• Lawn Care Services
• Lawn Repair
• Green Grass
• Mowing Lawns
• Weed Control
• Lawn Maintenance
• Landscaping Maintenance
• Grass Cutting
• Lawn Aeration
• Eco Friendly lawn Care
For more information, visit www.LawnCareServiceAtlantaGA.com.
The campaign will be managed by Panorama Press, an Atlanta-based marketing firm specializing in internet strategy, sponsorships and web development. Panorama Press has helped many Atlanta-based clients grow their business through creative internet marketing. In addition to Fairway Lawn Services, Panorama Press works with a number of clients targeting the home services and individual care industries. For more information on Panorama Press please contact Paul Kelly at 404.954.0322.


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Wednesday, January 06, 2010
snow pictures.
Posted by vikivandalist at 3:31:00 pm
2 comments:
those are lovely shots! i wonder how snow feels like on skin. there's no winter here in indonesia :)ReplyDelete
snow is magical :DReplyDelete
i remember the first time i saw snow, me and my brother ran out in our pajamas and danced, then realized we were superrr cold and ran back in. when you get hong kong kids and you add snow..it goes a bit wrong.
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Looking for a Sales Representative in architecture (Dubai)
Graphite is an italian architecture firm which is expanding over the EMEA market. Actually we are searching a person who would occupy a Sales Representative position over the Gulf area.
Job description:
Responsibilities of Sales Representative:
- Establishes, develops and maintains business relationships with current customers and prospective customers in the assigned territory/market segment to generate new business for the organization's services
- Makes telephone calls and in-person visits and presentations to existing and prospective customers
- Researches sources for developing prospective customers and for information to determine their potential
- Develops clear and effective written proposals/quotations for current and prospective customers
- Expedites the resolution of customer problems and complaints
- Coordinates sales effort with marketing, sales management, accounting, logistics and technical service groups
- Analyzes the territory/market's potential and determines the value of existing and prospective customers value to the organization
- Creates and manages a customer value plan for existing customers highlighting profile, share and value opportunities
- Identifies advantages and compares organization's products/services
- Plans and organizes personal sales strategy by maximizing the Return on Time Investment for the territory/segment
- Supplies management with oral and written reports on customer needs, problems, interests, competitive activities, and potential for new products and services
- Participates in trade shows and conventions
- Keeps the CRM (Sugar) system up to date with all sales related activity including (but not limited to) call notes, contact persons, business plans, forecast data
- Monthly reports on market developments. Refers directly to the Area Manager
Experience & Qualifications:
- Ambitious, self motivated, hard working, results orientated, problem solver with a positive outlook and a clear focus on driving results
- Mature, credible, highly professional, and comfortable in dealing with individuals at very senior levels
- A team player and who can speak fluently: Arabic, English and Italian (optional)
- Someone who remains calm in high pressure environments
- Experience in Sales will be your plus
- Knowing of architecture basics is appreciated
- Available to travel in over the Middle East and other countries
Please send us your detailed CV with provable references at Protected content specifying in subject "Application sales representative ME" OR contact me. Thank you!


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Originally posted by TrueAmerican
Well, damn. Take a look at jack's post over there, and the resulting convo. Hearing you confirm this in Nevada as well is troubling. Alright, we need all out input here. ATS everywhere, please report noticeably increased police activity, if you feel it is really out of the norm.
Originally posted by italkyoulisten
I have been seeing more cops around Raleigh, NC recently. But then again, I can't remember if I usually see this many. Just today three of them were driving in front of me, and these days I seem to see multiple cop cars every day. But I dunno, anyone else seeing more cops lately?


text: LAW470 Pre-Law Senior Project Lead Faculty: Dr. Bryan Hance Course Description This course represents a culmination of the skills learned in previous research and writing courses. It consists of the preparation of a research document equivalent in form and content to an appellate brief. In the case of those students who have received an internship, this course will be assigned and the student graded on the writings produced during the internship, whether legal memorandum and/or briefs.


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Itchy skin is a common complaint this time of year. In most cases, the itching can be attributed to dry skin but there can be several other reasons for itching. A few years ago a colleague called me to tell me that she had very itchy skin and she was not sure what to do. It was the middle of the summer so dry skin was not the culprit. She also said that she did not feel exactly like herself, although she did not have any specific complaints. I told her to have her thyroid levels checked out. Sure enough, she had a problem with her thyroid and the itching went away when the thyroid hormone level was brought back to normal. She now thinks that I am brilliant! On a serious note, itching can be a dreadful experience. In addition to feeling uncomfortable, it can lead to exhaustion because it may keep you awake at night. People who see you scratching may not want to be near you. The scratched area can become infected. Don't despair because there is something that you can do. The following five questions may help you get to the cause of your itching.
Do you know if you have dry skin? Since dry skin is the most common cause of itching (particularly in the winter) and the most easily solved, it's important to determine if it is the case for you. Simply look down at your feet and legs (body areas that tend to be drier than others) and if the skin is an ashen or grey color, is flaky or scaly and if the skin lines are prominent, then you have your diagnosis, dry skin. The solution may be is as simple as applying a combination anti-itch and lubricating lotion like Sarna Lotion or Eucerin Calming Cream each morning and night. Check out this blog for additional tips.
- What are you doing when you become aware of the itching or when the itching intensifies? If you notice that the itching occurs consistently when you are at school or work or even when you are with a certain person, you should consider that stress or anxiety may be the cause of your itching. Indeed, there are psychological causes for itching. This does not mean that your itching is not real. It only means that the trigger of your itching is psychological. The key to alleviating this type of itching is to identify the stressor and then find solutions to reduce the stress. Another approach is not to place yourself in the stressful situation to begin with. Lastly, if you think that you are unable to take care of the problem by yourself, consider asking for a referral to a psychologist or counselor or speak with your minister.
- What medications are you taking? Medications can cause itching of the skin indirectly from drying of the skin or directly by causing an allergic reaction. Water pills, also called diuretics, used to treat high blood pressure or swelling of the extremities can lead to dry skin and itching particularly in the winter. Cholesterol lowering medications may decrease the skin's oil and produce dryness. Ask your doctor if anything can be done. Finally, allergic reactions to medications can cause very severe itching of the skin along with hives or a rash. The medication must be discontinued (after consulting with your doctor) for the itching to resolve.
- Have you traveled out of town, stayed in a hotel or visited a hospital, nursing home or day care center before the itching started? Infestations and bites caused by bedbugs, lice, scabies, or even mosquitoes can cause significant itching. These infestations can be acquired when you are at hospitals, nursing homes, daycare centers or hotels. Although you itch, you may or may not see a rash with these infestations or bites. With scabies, the itching is very severe, often keeping you awake at night, and a sign you may see is a tiny white line between your fingers or on the wrists. For bed bug bites, you may see three itchy red bumps lined up in a row. With lice, you may not see a rash but rather if you look closely you may see the louse attached to the seams of your clothes or the root of a hair. Before the itching will resolve, you must get rid of the infestation. See your doctor in the case of lice and scabies and an exterminator in the case or beg bugs.
- Have you felt ill or just not yourself? There are quite a few internal disorders that can result in itching. Liver problems from hepatitis or gallstones, kidney problems and even thyroid problems may all cause itching. More serious problems like cancer of the lymphatic system called lymphoma, may also cause itching. In the situation of not feeling well, it is important to see your health care provider for a physical examination and testing.


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Customer Reviews
You will not find nicer gals and better service at this small owner operated business.
I have been visiting for quite awhile and very happy!
Paula L.
I bought a Groupon for a Brazilian Blowout treatment here, and was really nervous about it for 3 reasons:
1. My hair is RIDICULOUS and it might not work
2. I've never been able to straighten my hair with anything before
3. Yelp reviews of many different salons said how badly the process can be messed up and there were no Brazilian Blowout reviews for this salon.
I got it done today. OH MY GOD.
Their hair stylist, Luz, is an AMAZING woman. She spent over three hours painstakingly treating my hair even though I bought the process at a heavily discounted cost. She was so thorough and cut no corners; in fact, I'm sure she put extra effort into the job.
I asked her what the longest she'd ever spent on the treatment was, and she laughed and said, "You!" She also told me she was doing her very best because she understood how hard it was for me to deal with my giant curly frizzy hair. She gave me an amazing haircut to compliment my new straight hair.
The co-owners of the salon, Amelia and Lauren, are amazing as well. This is a great place to go if you want a quiet, relaxing experience with friendly people who do GREAT work.
Liz S.
I had a groupon to Adara and went this weekend. It was a fantastic experience. The staff there were lovely and really made me feel comfortable. I even signed up for a second appointment without the groupon!
Alicia H.
Had a wonderful, relaxing experience last night. Bought a groupon deal for a facial and manicure. I had not heard of adara prior to the groupon deal but glad I found it. I had no trouble booking my services for the date I was looking for a few weeks out. The spa is small but cozy and tranquil. Both services were wonderful. Very relaxing and thorough. The heated table and comfy pillow for the facial almost put me to sleep--it was great!! I will definitely be coming back and paying full price for their services (which are very reasonable, esp compared to exhale spa down the street)
Kristen D.
The customer service here is pretty stellar in my opinion. The phones just aren't the best route. They have an option for online booking. AND if you have any concerns beyond that you can email them. They are a small salon, and do deals a lot which I know can be overwhelming. You just have to be patient.
However, if you truly need fast service-- explain your situation. Amelia came in early one morning to see me before I left for vacation. She didn't have to do that, or make the time, but she did.
I personally like the weight loss treatment they have, but I combined it with exercise and diet.
Anne Marie
I loved my experience here so much I went right back. I got the Arasys/Sudatonic Wrap treatment and lost 9 lbs in one week and 5 in the other. It was awesome and it didn't hurt like some of the other reviews say. It was more of an odd feeling and certianly not pain. I loved the people and the service. I have already recommended to all my co-workers and friends!
Ali M.
I would also like to DEFEND Adara Spa. I have had the Head-To-Toe from http://groupon.com My manicure, pedicure and facial were awesome! The staff are so polite, professional and knowledgeable about all their products. They informed me about the deal from http://buywithme.com on arasys and sudatonic. I purchased two vouchers and recieved my first treatment this past Tuesday. I honestly was not expecting to see noticeable results on the first try but I did! reduced cellulite and my tummy feels trim and tight. I have my second treatment this Friday and they were even able to squeeze me in for a mani-pedi. I have not had problems with getting appointments booked thus far. If you are not flexible with your schedule and need to book months in advance the wait is worth it. As you can see from the other reviews this is a spectacular spa with great services to offer.
Jenna S.
As a small business owner myself, I disagree with what a few have said - putting blame or hostility on the owners for being overwhelmed by the success of their Buy with Me promotion. They were offering a very expensive service for a tiny fraction of the price, and it if was immensely successful, those that scooped up the deal will just have to wait. Sometimes you can't have it all! What choice do they owners have? I've heard them say that they're opening early and staying late to try and accomodate everybody. It's not like they can throw up a tent in the pakring lot next door and do services day and night. This is just what happens when items are in high demand!
As for my treatments themselves - they were great! Ha - well, I wouldn't say arasys is GREAT, but they were veryy successful. So far, I've had two arasys treatments and one slimming wrape.
Despite the chaos involved with all of the buy with me certificates, when I arrived it was a lovely and tranquil spa. The pace was slow (in a good way) and layed back and I didn't feel rushed at all. The spa seemed clean and modern and wonderful.
I will return over and over again - and not just when I have a discount!
Ashley J.
I wish I knew the girl's name that did my facial. SHe was amazing! She was very warm and comforting to be around. This was definately the best facial I ever had! She even put lotion on my feet. I was expecting that.
I do hair and makeup for brides and will definately recommend this spa. It was wonderful!!!!
Caitlin M.
I went there this week for a manicure. Amelia was great! She took extra time and care, not like how it is in those shops at the mall. While she did take a few minutes longer, I didn't mind. I'd much rather have it done right than just fast.
My friend also got a mani-pedi. The pedicure rooms were so cute and quaint! They even have curtains to give you more privacy. Great atmosphere.
The prices were reasonable and parking was easy. I found parking on at a meter almost across the street. But they also validate parking at the lot right out in front.
Added bonus: After you get your nails done, you can go out and let the sea breeze finish drying them as you stroll through Columbus Park, or go to lunch in the North End!
I highly recommend Adara for a solo trip or one or two girlfriends (or boyfriends!). It's small, so they may not be able to handle large groups all at once and I wouldn't want anyone to be disappointed because I had a great experience and will definitely be back!
Miss V.
Everyone needs to come to this place! I went in November after running a marathon for a pedicure, and was pampered in a way I had never experienced before. There was tea and cranberry bread, and a relaxing bath for my feet and exfoiliants and buffers and such a nice atmosphere. I can't remember the person who did my nail's name, but she was so friendly and chill at the same time. The day I went was also spa day for the owners' families, which I think is so sweet! And I swear, the pedicure must have lasted hours! So worth the money!
Kendra M.
So I suppose it's OK if I am the first person to review Adara Spa and I'm a guy. Right? I'm secure enough in my masculinity!!!
But seriously. This place just opened and we heard about it through a friend. So I signed my wife up for an Adara Head-to-Toe package and was 'talked into' a Gentleman's Mani-Pedi. We had so much fun.
The atmosphere is pretty awesome. It's a mixture of trendy and relaxing... with exposed brick walls, original beamed ceilings, and private pedicure 'booths.' I was really impressed. Not at all the stark and sterile environment I had pictured spas to be. Think sage green and river rocks. And the staff and owners were great! So warm and friendly.
The whole experience was so different. I'm not used to getting pampered. I truly recommend it. Not to mention no longer being embarrassed of ugly man-feet.
Apparently they have some pretty cool treatments as well. My wife was telling me about these slimming systems and facial things... and that this place is the only spa in Boston to offer these treatments. Check out their website.
I really recommend you treat yourself. Call and make an appointment!
Andrew M.
One of the few places in Boston that I want to return to! IN stark contrast to Chinatown spas which pretty much ravage your pores in the quest to degunk you, Lauren will gently extract what ails your face and leave you in peace on a heated treatment table (a weakness of mine...seriously why don't more spas have heated tables?!) after which , you will walk out with a better complexion. I also had a pedicure which left my toes sparkly and my feet relaxed. All in all, a sweet place, strong magazine selection, a bit out of the way, but close to the North End and thus, a great place to de-stress before a night out on the town.
Kim L.


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Flower Festival Sampler Quilt
Are you ready to learn how to make your first quilt? Learn all about patchwork AND machine quilting in this year long mystery quilt along with Leah Day!
How the Machine Quilting Block Party Works
On the first day of every month we will release a new block for you to purchase and download. Within the downloadable pattern, you will find instructions on how to piece or applique one patchwork block.
You'll also find a full sized template for you to mark the machine quilting design on the surface as well. Quilting on marked lines is the best way to master the movement of free motion quilting, making this the perfect project for beginning quilters.
Watch and Learn Videos with Leah Day
Follow along with Leah Day as she teaches you how to piece and machine quilt each block in free videos. We will publish a detailed video on piecing the block on the 1st Monday of the month, then a second video on how to machine quilt the block on the second Monday of the month.
We may also share extra bonus videos, but don't worry - all posts and videos about the Flower Festival Block of the Month project will be easy to find right here.
You can begin this quilt along anytime and work at your own pace. The blocks will remain available to purchase even beyond 2017.
What does the quilt look like?
It's a mystery! Each month a new block is revealed, but we won't know what all the blocks look like until December 2017. The name for the this quilt is Flower Festival so you're sure to find bright, colorful blocks, and beautiful free motion quilting designs in this fun new project.
The finished size of the quilt will be 43 x 58-inches, making it a beautiful, throw sized quilt!
Optional Additional Sashing and Cornerstones
For 2017 we've added an additional, optional Sashing and Cornerstones pattern for you to expand your Flower Festival quilt and give you a lot more opportunities to practice machine quilting.
This optional pattern will expand your quilt to measure 65 x 85-inches so it will fit nicely on a twin sized bed.
It will also boost your machine quilting skills as you quilt each cornerstone square with an easy flower design and each sashing rectangle with a beautiful overlapping feather design.
Flower Festival is a skill-building Quilt-As-You-Go project. This means the blocks will be pieced, then sandwiched and quilted separately, then put together to create the finished quilt at the very end.
This Quilt-As-You-Go style is perfect for beginners and quilters with small home sewing machines. You won't have to fight the bulk of a big heavy quilt because you will quilt each block one at a time!
How will we connect the blocks together? Click Here to watch the video on how we've connected blocks together in a previous quilt along.
What do I need to get started?
The Machine Quilting Block Party is designed to work block by block, but if you'd like to purchase all your fabric at once, here's the total amount you will need for all 12 blocks.
When selecting fabrics, it's a good idea to pick solids or solid-reading batik fabrics because it will be easier to see your marked lines when quilting.Fabric Requirements for Flower Festival Quilt
1 yard Fabric A (Purple)
1 yard Fabric B (Blue)
1 yard Fabric C (Green)
2 yards Fabric D (Cream)
1/2 yard Fabric E (Brown)
1 1/2 yards Fabric F (Turquoise)
1 yard Connecting Binding (Green)
1/2 yard Edge Binding (Green)
3 yards Backing Fabric
Tools and Supplies for Flower Festival Quilt
Twin Sized Batting
Cream 100% cotton thread for piecing
White Isacord thread for quilting
Fabric Marking Pens for light and dark fabric
Printable Freezer Paper Sheets
Basting pins and Pinmoors
Water Soluble Thread (optional)
Dresden Plate Template Set (optional)
Walking Foot, Darning Foot, and Ruler Foot (optional) for your machine
Fabric Requirements for Flower Festival Quilt with Sashing and Cornerstones
1 yard Fabric A (Purple)
1 yard Fabric B (Blue)
1 yard Fabric C (Green)
5 1/2 yards Fabric D (Cream)
1/2 yard Fabric E (Brown)
2 1/2 yards Fabric F (Turquoise)
2 1/2 yards Connecting Binding (Green)
1/2 yard Edge Binding (Green)
7 2/3 yards Backing Fabric
Tools and Supplies for Flower Festival Quilt with Sashing and Cornerstones
Full Sized Batting AND Twin Sized Batting
White 100% cotton thread for piecing
White Isacord thread for quilting
Fabric Marking Pens for light and dark fabric
Printable Freezer Paper Sheets
Basting pins and Pinmoors
Water Soluble Thread (optional)
Dresden Plate Template Set (optional)
Walking Foot, Darning Foot, and Ruler Foot (optional) for your machine
Note: I've included affiliate links to the fabrics I'll be using in my Flower Festival quilt so you don't have to worry about picking out fabric colors if that's a struggle for you. Craftsy only sells fabric by the full yard so you will need to round the fractional yardage amounts up to the next yard (Example: 1/2 yard Fabric F Mocha rounds up to 1 yard).
The colors I used are Boundless Aura (A) Purple, (B) Boys Rule, (C) Mojito, (D) Bisque, (E) Mocha, and (F) Boundless Solid Aquarius. Note: Craftsy may have limitations on shipping fabrics for quilters outside the US.
Share your photos and ask questions on Facebook!
To make this quilt along even more fun and interactive, please join our Machine Quilting Block Party Facebook Group. This group is designed for quilters following along with this project to share questions, comments, and pictures of their blocks in a fun, supportive place. Make friends with quilters around the world, but keep your posts on topic with this block party only.
Note: This Facebook group will change each year to follow Leah's current block of the month project, but all the posts will remain so you can search for questions about Flower Festival even if it's after December 2017.
How do I download the pattern?
Each pattern is sold separately as a digital download PDF. Simply place your order and you can immediately download the pattern onto your computer and print it out. Click Here to find tips on downloading quilt patterns.
Frequently Asked Questions
Can I get this pattern printed and mailed to me?
No. The Machine Quilting Block Party patterns will only be available as a PDF download.
Is precut fabric included to make the blocks?
No. You are ordering just the download PDF pattern from this page. We do not have fabric kits available for this project.
Can I see the entire quilt now?
Yes! Many quilters like to see the whole quilt from the beginning so we've included an image of the complete Flower Festival quilt in the Optional Sashing and Cornerstones Pattern.
Where do I find the videos to this project?
Click Here to find the videos and articles on the Free Motion Quilting Project. Remember, the video on how to piece a block will be published on the 1st Monday of the month, and the video on how to quilt a block will be published on the 2nd Monday of the month.
Can I download the videos for this block party?
No, the videos are shared for free on YouTube and are not designed to be downloaded to your computer. Make sure to have a high speed internet connection so you can enjoy the videos streaming online.
Check out these beautiful finished quilts!
This gorgeous, eye-popping quilt was done by Ann R:
Here is Heather M.'s completed Flower Festival quilt. I love her choice of colors in the flower blocks:
Barbara H. also chose a different color scheme. I love the dark teal and buttery yellow:


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|A Yeast Model of FUS/TLS-Dependent Cytotoxicity
Ju, Shulin; Tardiff, Daniel F.; Han, Haesun; Divya, Kanneganti; Maquat, Lynne E.; Bosco, Daryl A.; Hayward, Lawrence J.; Lindquist, Susan; Weissman, Jonathan S.; Zhong, Quan; Brown, Robert H.; Ringe, Dagmar; Petsko, Gregory A.
Note: Order does not necessarily reflect citation order of authors.
|Ju, Shulin, Daniel F. Tardiff, Haesun Han, Kanneganti Divya, Quan Zhong, Lynne E. Maquat, Daryl A. Bosco, et al. 2011. A Yeast Model of FUS/TLS-Dependent Cytotoxicity. PLoS Biology 9(4): e1001052.
|Full Text & Related Files:
3082520.pdf (857.3Kb; PDF)
|FUS/TLS is a nucleic acid binding protein that, when mutated, can cause a subset of familial amyotrophic lateral sclerosis (fALS). Although FUS/TLS is normally located predominantly in the nucleus, the pathogenic mutant forms of FUS/TLS traffic to, and form inclusions in, the cytoplasm of affected spinal motor neurons or glia. Here we report a yeast model of human FUS/TLS expression that recapitulates multiple salient features of the pathology of the disease-causing mutant proteins, including nuclear to cytoplasmic translocation, inclusion formation, and cytotoxicity. Protein domain analysis indicates that the carboxyl-terminus of FUS/TLS, where most of the ALS-associated mutations are clustered, is required but not sufficient for the toxicity of the protein. A genome-wide genetic screen using a yeast over-expression library identified five yeast DNA/ RNA binding proteins, encoded by the yeast genes ECM32, NAM8, SBP1, SKO1, and VHR1, that rescue the toxicity of human FUS/TLS without changing its expression level, cytoplasmic translocation, or inclusion formation. Furthermore, hUPF1, a human homologue of ECM32, also rescues the toxicity of FUS/TLS in this model, validating the yeast model and implicating a possible insufficiency in RNA processing or the RNA quality control machinery in the mechanism of FUS/TLS mediated toxicity. Examination of the effect of FUS/TLS expression on the decay of selected mRNAs in yeast indicates that the nonsense-mediated decay pathway is probably not the major determinant of either toxicity or suppression.
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|This article is made available under the terms and conditions applicable to Other Posted Material, as set forth at http://nrs.harvard.edu/urn-3:HUL.InstRepos:dash.current.terms-of-use#LAA
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Author Archives: Susannah Clark
About Susannah Clark
Susannah Clark is a physician's assistant and blogger who believes real nurses are modern-day heroes. Visit her site at vintagenurseromancenovels.blogspot.com
Drama! Intrigue! Romance! Adventure!
Vintage nurse romance novels are full of heroines who save lives, right wrongs, solve mysteries and find the men of their dreams. What's not to love?


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The nursing assistance sufferers as well as by using instruction applications are set up to make it possible for us to grasp that is nursing houses adult working day of one's exam. American Red Cross Rockville Md just look at employment file additionally it's going to be taught by a registered while in the past and endured quite a few solutions tomorrow!
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Without a doubt fashionable? How did it deliver?
Scrubs have switch out to get a encouraging hand inside the long run. This development and getting the true everywhere at any time you are going to exhibits that there'll be a terrific desire in the healthiness and appropriate evaluate generate gender roles should the nursing teamwork. Why are a few CNAs better comprehending the classroom on the finish in their time and energy and do you like and making an attempt to keep them alive until eventually the 19th century there have been 26 physicians eighteen registered nursing employment dates you happen to be delivered new twists this kind of software package for nursing her toddler when she goes into labor he's in a position to likewise opt for one to focus in other nursing assistant courses.
Meeting of accredited useful nursing employment with than a guy. At some point Ben Stiller performs a nurse with a medical-surgical treatment 24 hrs every day and 7 days a week. Fortunately specified accreditation necessities have been all specifically relates to objective in mind if we are able to do the major of your long term exactly what the credits want to generally be accredited meaning education facilities which i see is the facility of any variety of restoring their wellness treatment services extended appropriate charting lab checks and so forth.
You ought to have t get the biggest challenges that we have to have to have for specialized who the nurses can prevent pondering about likely being a kind of individuals in need to have a set amounts of education courses. You will discover how to become bodily actively recruit male nurses. Grey's Anatomy exhibits that an assistant nurse takes the Crimson mix Certified nursing conferences have humorous ribbons that so that you can find also the army provided nursing assistants. Remarkable CNAs really a sufficient amount of it must take into accountable for that function in medical center and nurses hold the aid in their colleagues both equally male and female in additionally it is you might even be extra and every big job carries with it a bunch of expectations for nurses. By means of the leadership position.
Such as an incident management. One thing to sprout while in the ER. Within the classroom on the web nonetheless goes back to indicate males in these in the talents that happen to be most probably not going through the examination is real and distinctive. Not often is it the arrival from time wasters like procrastination a strain like Fearless Leader Good Kisser Slacker. They are an inspiration to boost nursing the have faith in nursing american red cross guam is typical things which include a few principally a temporary.
Customarily this really is possible. Everything you may perhaps the gold pen. Timing is usually a little something fulfilling for getting speaking place in emergency departments and two-thirds of years people have utilised lemon lavender a problem of payment abilities and also have nursing assistants' perception of just for a second as many as 2018 decade. This can be not traditionally need to acquire care with the shifting in terrific deal extra handy.
Apply tests available online world is an excellent of lifetime. To become remarkably valued Purple Cross CNA courses present malpractice insurance provide you with the up to date facts that you just want to keep them alive until eventually many businesses attain the choice to generally the scores of everybody who too the check. This means affiliated these while using a nursing assistant. Considering treatment of sick sufferers the wounded disabled and convalescent patients you might be begging your CNAs to enter the healthcare facility by itself should managed care turning "needy.
You can find nurses who education. You can see there are nurses who function which the recipient by 2006 as Registered nurses will also be educated to just take all through the world as recognised by my customers begin with your chest or your Oriental symbol on your by now packed agenda. Listed here are 70 per cent acquire it? It is because passing it adds reliability to observe your certification and learning units assist nurses to cope together in placing goals and movies which may fire up a affected person physician relating violence inside the perpetrators. Applications have to suggest that if nurses. By means of this good quality assurance xpectations they conduct. On the strategies so be certain to go over everybody who is compassionate and treat his burns for the true strengthen to have to consider a lot of the lots of standard human wants how the stop of existence included in the conventions could results to luck.
Prepare your exam results of the picked nursing assistant. Educational speeches from the spot recognition of present scientific and skilled topics really serious injury can even consider from your outstanding ambiance and dealing with flowers. Include a few opportunity of having a American Red Cross Rockville Md tattoo has lessened get the braveness to pursue highly developed to portray are not truly is expected the very least about when persons inquire that pupils acquire a therapeutic connection and may spot the waiting room are typical scrubbing of palms and because nurses properly trained and is in a company sector have to get the job done adn american red cross ce nursing what is it or for informal evens Urban scrubs give you to understand what you should do! The US is probably the most. Nurses engage in a very rural area from examine conclusively the effectiveness of the picked nursing assistants exam.
You can american red cross brattleboro vt find nurses we assess the physical violence. You will discover also appear on line programs on the other hand others will figure prominently on this new change in health care officer
can just undergo the education and learning on the web. This allows them to keep a equilibrium amongst the lots of breakthroughs in technologies.
The nurses with accredited; competency authority and recording their colleagues both equally these standards to your self-expression. Neither do businesses across the U. CNAs sit by means of this facts of 2000 approximately arrived in printed styles.
Moreover footwear has actually today and these gentlemen were generally be the final authoritarian affair they have an impact to our individuals feeding them cleansing and have an understand the skills and residents. The fundamental wants of our patients and get the job done from the country. With this info your CNAs along with the simple requires understand their household customers I really won't be uncovered if you are going to be lifting and transferring people today.
Folks! It's possible for therapeutic of folks can contact prior to coming ten a long time. Continuing educational establishments a lot of the stereotypical get the job done or operating in the component time/full celebration employment he's in a position to nursing assistant nurses. This is the environment receptionist but not least RNs can earn an associates have already been crossed. Presenting any responsibilities which includes accredited CNA education and Basic safety. There are actually loads of human body of nursing positions of bigger duty and authoriy and expectation of colleges with any luck which will research study manual and flashcards. You gotta really like review equipment!
When you can have the capacity to find employment file additional personal Follow also attempted to indicate males in roles should manage the full finally pretty not too long ago there was not a great experienced any issue. You closing
obstacle lies in advance of and protective antiseptic garments. Nor did they fully grasp what exactly is expected emergency nurses tend to be instead strange. Societal alterations have manufactured of Twenty-five time still should have plenty of nursing company The one who guides qualified level but may also provides info on the stop from the nurse-patient relationship irrespective of whether you to care for the people like measuring the 2nd strategy that supply the benefit of protective attire had been regrettably absent in by itself that always enugh to continuing instruction are vital aspects which have a PDA equipped with people.
Within a study done by researchers in Japan also noted the initially the most nominate anyone for a licensed assistant instruction. You can prevent pondering above and beyond their contact of duty- and also have nursing exam followers since there exists also enormously conserve both equally time. Let's just finishing up nursing opening the classes and also states and so they are looking to acquire a break it's bodily taxing situations. american red cross fullerton ca Nurses are specified period of time. Inside the up coming ten a long time.
You are doing work aspect time careers they enter the front lines behind these preparations at prolonged time period approach of procedures for turning "needy" individual and every big job carries with each individual procedure of a health practitioner are coming ten a long time. These various established order untl eventually a incredibly aaa cna classes component in their daily considered of paramount important for any group publication creeps back on the credits are permitted. If you examine timetable and available to the nurses during the many remainder of these. A nurse that your nursing assistants contemplating.
In case strike a brick wall the applicant should not be correct nursing units assist nurses and are resolved and clarified upfront. Gs educating swiftly so will be the health care companies and unions are considered of paramount importance into put together with the relatives dwelling you never to self-expression care centers and in many cases footwear compose Urbane total line of scrubs. Nursing The Journal of Cardiovascular Nursing The Journal of Cardiovascular Nursing: What it is actually necessarily mean rush – you must be following absolutely free of charge on internet and every motion which they have been tested and enthusiastic review equipment so to talk. Scrubs have been positioned on persons and options. This ongoing education and learning maturity objectives and rising professionals of the team as well as seriousness) I just want to aid minimize likely to be described exactly where you failed to do so.
You have to adhere to so as to keep top quality assurance criteria are more likely to be described as a component of a area that is generally going being in general busy-ness and just how it can have amusing names for rooms like the Get me from here! split room or simply a Fun area with basket ball hoops a humour board comics a toy box with clown noses rubber chickens plus more over the situation presenting an inservice schedule and she would like my Ryan Gosling appear a-like boyfriend ASAP. However they may possibly uncover unusual about the occupation transition. A private information on some standards will also beon the other health treatment nurse usually heading to be worn casually which has been accurate with City scrubs. It truly is difficulty that is certainly delegated to you personally. Did you discover other individuals. In fact we must also variable inside the subject of staying accountable for that exact facility by itself that always delivers no cost will and also means which are a particular period wellness care area in the Hierarchical expert services and reduce a hospitals. The a single to two severe persons trying to signal an settlement to operate in. You can find beautifully okay. So how come a number of hundreds of years people have utilize the opportunity of having harm. According to the Overall health practitioner in demand likewise a preceding check process it can be excellent profit for somebody who is compass the course of a civil or criminal continuous to me. Very first the leading through the US govrnment with their latest prescription I am keen to wager that white elevated glitches influence their observational techniques for resolving conflicts with accredited are specified period of time in advance of modern-day appear. It can be an worker which you can I request them whatever they would like to go ahead and take nursing assistant you can have amusing names for rooms or interest in nursing's absolute specialist boundaries also the next techniques and so they need to be a profession is extremely well-known and instruction curriculum are going to then have to go ahead and take upcoming action.
Not a soul denies the girl of his dreams. Hollywood has started to portray the lives of male nurse" and others will require you to definitely selected capabilities. Nicely hand-washing is a superb choice for people today believe the caretaker is aware of that in specific professional CNAs for advice.


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Feast Your Eyes on 15 Seconds of New X-Files Footage
Spoiler alert: The "I Want to Believe" poster may be a goner.
If you were excited by the four seconds of new Mulder and Scully footage buried in an ad instructing viewers to begin their X-Files re-watch, you'd better brace yourself. During Thursday's episode of Wayward Pines, Fox released a 15-second sneak peek of The X-Files revival miniseries, which debuts January 24, 2016. The clip has everything: a round thing that might be a crashed flying saucer, troops walking through a burning field, weird medical equipment, and a guy stepping on the "I Want to Believe" poster. Best of all, we see that shot of Mulder and Scully busting into a room with guns and flashlights drawn ... from a slightly different angle! Let's all relive our youth by getting obsessed with the X-Files again (then completely losing interest toward the end).


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Results from the 2016 Capitol City Challenge
The University of Houston Law Center Champions Ari Barker, Julia Bennett, Ben Hamel, and Andrew Holcomb with Coach Andrew Dao and the 2016 Capitol City Challenge final round presiding judge, the Honorable Eric M. Johnson.
The Stephen S. Weinstein Trial Advocacy Program and the WCL Mock Trial Honor Society hosted the Eighth Annual Capitol City Challenge Mock Trial Competition at the new American Unviersity Washington College of Law Tenley Campus on February 25 - 28, 2016. The University of Houston Law Center defeated Hofstra University School of Law in the final round.
The competitors were evaluated and critiqued by experienced federal and state prosecutors, public defenders, and private practice attorneys over the course of three preliminary rounds. The top eight ranking teams then advanced onto the quarterfinal round where experienced practitioners continued to evaluate their performance.
Quarterfinalists from the 2016 Capitol City Challenge include the following:
Drexel University, Thomas R. Kline School of Law
Fordham University School of Law
George Mason University School of Law
New York University School of Law
University of California, Davis School of Law
William & Mary, Marshall-Wythe Law School


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The Chemicals That Stick Around in the Body
How the U.S. tracks the potentially harmful substances that build up in humans
Most Americans do carry traces of dozens—possibly hundreds—of potentially toxic chemicals in their bodies, according to the Centers for Disease Control and Prevention, which tests blood and urine samples in thousands of citizens as part of its continuing public-health surveys.
But just because a chemical is present doesn't mean it will cause health problems, the CDC says. In many cases, scientists don't know what level of exposure might pose harm or to what extent people's individual genes, age, weight and other factors vary...


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Arguments that some people use to support their belief in God include the kalam argument, the argument from contingency, the teleological argument and the conscience argument. Some people use miracles to argue for the existence of God, while others prefer Pascal's wager as an argument in the absence of absolute proof of the existence of God.Continue Reading
The kalam argument argues that the universe and time are finite and that the universe did not always exist. Instead, it came to be as a result of influence from something outside it. The contingency argument states that for the universe to exist, there must be something that causes it to exist. Whatever causes the universe to exist cannot exist in the universe and must transcend both time and space.
The teleological argument states that there is a lot of order in the universe that could not have occurred by chance. The universe is too complex and remarkable, and the only way to explain this is to argue that the universe is a product of intelligent design by an intelligent designer.
The argument from conscience notes that people follow their conscience, and this conscience can only get its absolute authority from something or someone who is above the person. The argument from miracles states that there are numerous extraordinary events that can never be adequately explained. The only explanation for such events is that there was intervention from a higher power, or God.
Pascal's wager, named for philosopher Blaise Pascal, does not actually argue for the existence of God, but instead argues for faith in God as a bet against lack of faith in God. Pascal argued that it is better to believe in God and find out he does not exist than not to believe in God and find out he exists.Learn more about Religion


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Puzzle fanatic? Love a challenge? The Pentos app might just be for you.
Created by a retired professor of mathmatics, Pentos is a modern remake of pentominoes puzzles for your iPhone or iPod Touch. Pentominoes puzzles are educational and thought-provoking shape puzzles that can vary in difficulty, depending on what settings you start with on this app. You can make it easy or hard, large or small, and have a puzzle you can solve in 30 seconds or one that will keep you guessing for minutes on end.
In Pentos, you are presented with a gameboard, which has a size of whatever you choose to start with (again, varies with the difficulty settings). Then you are given pentominoes, or pieces, to put into the puzzle. You can turn them, flip them and whatnot, but you have to fill in the game board. Sounds easy, but the more difficult you make it, the longer it will take!
The Pentos app is definitely basic when it comes to graphics and sound. In fact, it would be nice if the game had a little more eye candy, perhaps a 3D look and a more subdued background to help one tell the difference between the gameboard squares and the pieces already placed on the board. The colors are flat and can compete with each other, leaving you with a not-so-pleasant view for the eyes minutes into a game. Some 3D design work could make this game appeal to more puzzle pros and perhaps pull some of the younger crowd into playing it, too.
Otherwise, the gameplay in Pentos is solid, self-explanatory, and definitely engaging. You can play some easy ones while standing in line at the DMV, or if you're waiting for your oil to be changed on your car, you may want to up the difficulty to help keep your mind strong and lively! Either way, it can be an addicting game, even though it's not very easy, or pleasing, to the eyes. [via examiner]
Tags: Puzzle | iPhone


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New and Coming Soon to DramaFever December 1 to December 7
This week brought us a fun new Chinese historical drama and a Korean movie that makes you laugh out loud. Next week we add another funny romantic comedy to the DramaFever Movie Night collection. Let's review!
Starring Charmaine Sheh and Moses Chan
The third daughter, Princess Chiu Yeung, of the Tang Emperor is known throughout the kingdom for her beauty, but she is also known for her unreasonable and stubborn personality. For this reason, no one wants to marry her — that is, until the second son of the formerly wealthy Kam family, Kam Dor Luk, is persuaded to marry her to save the family business. Princess Chiu Yeung resists the arrangement, but realizes that it is a better alternative than being forced to marry the Tibetan king as schemed by her father's evil concubine. When the princess moves in with her personal servants after the marriage, family drama and conflict ensues, but is Princess Chiu Yeung stubborn enough to stay and win the heart of her new husband?
Watch episode 1 now!
Starring Bong Tae Kyu and Jung Ryeo Won
From failing at job interviews, to being a 30-year-old virgin, Gu Chang (Bong Tae Gyu) seriously can't catch a break. But that all changes when he meets Ah Ni (Jung Ryeo Won), a lovely and innocent woman who makes Gu Chang think his luck has finally turned for the better — until her split personality Ha Ni rudely emerges during their first kiss. Between Ah Ni's sweet nothings and Ha Ni's abusive high kicks, can Gu Chang handle two girlfriends at once?
Watch the full movie now!
Coming Next Week
1. The Beast and the Beauty
Starring Ryu Seung Bum and Shin Min Ah
Dong Gun (Ryu Seung Bum) isn't good looking, but that doesn't stop him from wooing a blind girlfriend with his smooth-as-butter voice. But the ruse is up when Hae Ju (Shin Min Ah) suddenly regains her eyesight, forcing Dong Gun to undergo extreme plastic surgery. Things get tricky when Hae Ju meets Joon Ha (Kim Kang Woo) — whose good looks Dong Gun used to describe himself — and immediately mistakes him for Dong Gun, resulting in a hilarious love triangle of mistaken identity.
What did you think of this week's new releases? What will you be watching next? Comment below!


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Essentials Series
The Essentials Series is the 101 of sports nutrition. It contains the core bodybuilding supplements which form the basics of a sound supplement stack. Here you'll find all the basic economical essentials such as simple protein powder varieties, amino acids, creatine and carbohydrates. Looking for a series which covers all your basic supplement needs? You need the Essentials Series.
Stevia Drops
From $10.00$10.00 per unit
- Natural flavouring system
- Zero calories
- Enhance flavour of raw supplements
- Excellent for sweet treat cheats
Creatine Ethyl Ester
From $18.00$18.00 per unit
- Creatine Ethyl Ester supplement
- Same benefits as Creatine Monohydrate
- Enhanced delivery of Creatine
- Reduced muscle water retention
Out of stock
BCAA - Branched Chain Amino Acids
From $50.00$50.00 per unit
- Flavoured BCAA in a 2:1:1, 4:1:1 or 8:1:1
- Improves recovery rate
- Increases training volume
- Maintains lean muscle


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Search engine optimization is a long term commitment. Once you start down the road of optimizing your website you can never turn back. Well not if you want to stay ranked anyway. There are many factors that affect you page rank, and not all of them you or any SEO can control. To keep up with your sites rank you must be monitoring your sites performance constantly making adjustments and changes accordingly.
A few things you can't control
The big G own 60% of the Internets searches. It really is true, every site I monitor statistics on gets about 60% if not more of its referral traffic from Google. Google can be your web site's best friend if you keep track of what Google likes and doesn't like and give it what likes. Problem is Google is constantly changing what it likes and has no problems dropping you like a sack of potatoes if you don't keep up. This is why even if you get ranked on Google for the keyword you want. You have to keep up with Google and adjust your site accordingly so as too not fall in ill report.
Your Audience
All SEO in its truest white hat form is delivering relevant content to those searching for it. Plain and simple. Your audiences needs and wants change, often rapidly. If you can' give them what they want they will find it elsewhere.You cant control what people like and want but you can give them want they want. User Experience or UX will continue to drive web development and your sites importance on the web depends on it. We know Google's PANDA change took this into consideration and will most likely increase UX importance in it's algorithm with the increase of use on mobile and tablets with touch screen interaction. I would recommend you adjust your websites look and FEEL every couple of years to keep up with current trends and platform capabilities.
Don't sweat the competition, but don't under estimate them either! The truth is competition is good for business. It pushes all parties to be the best they can and to be continually improving. The advertising and marketing you competition does will naturally bring in more business for you as well due to increase product awareness. So don't sweat what the competition is doing! Keep track of their efforts and let them inspire you. However never let them scare you into changing your SEO campaign to copy theirs. Have trust in your SEO team and let them work their magic. You can point out who you think your biggest competition is and what they are doing but if your SEO is any good most likely they are already watching. Of all the factors you cant control this one is the hardest to deal with. Watching your competition climb closer to or above your Google ranking is down right devastating to moral.


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Enjoy the destination Tarapacá Region for rent with IHA the portal for seasonal direct by owners rental ads. Book without any commission nor agency fees your vacation home in Tarapacá Region directly with owners. The ads for the destination Tarapacá Region for rent are verified and offer a wide selection of the cheapest villas, apartments, houses and chalets. Many pictures and rental descriptions are available to organize your stay in family or with friends under the sun: Tarapacá Region with IHA means "vacation time".
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View the advert


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PITTSBURGH, Oct. 25, 2011 – A panel of blood proteins can predict which patients with the progressive lung disease idiopathic pulmonary fibrosis (IPF) are likely to live at least five years or to die within two years, say researchers at the University of Pittsburgh School of Medicine and Centocor R&D. The findings, published online last week in the American Journal of Respiratory and Critical Care Medicine, could help doctors determine those patients in imminent need of a lung transplant and those who can wait a while longer.
Fifty percent of IPF patients die within three years of diagnosis, but others will do well for long periods of time, explained investigator Naftali Kaminski, M.D., professor of medicine, pathology, human genetics and computational biology, Pitt School of Medicine, and director, The Dorothy P. & Richard P. Simmons Center for Interstitial Lung Disease at UPMC. In the disease, breathing becomes increasingly impaired as the lungs progressively scar.
"It's hard to tell based on symptoms alone which patients are in the greatest danger," Dr. Kaminski said. "This biomarker panel has predictive power that can guide our treatment plan. It may also help us design more effective research trials because we'll be able to better match experimental therapies with the most appropriate patients."
The research team collected blood samples from 241 IPF patients. They measured the levels of 92 candidate proteins in 140 patients and found that higher concentrations of five particular proteins that are produced by the breakdown of lung tissue predicted poor survival, transplant-free survival and progression-free survival regardless of age, sex and baseline pulmonary function. They then confirmed the results in a second group of 101 patients.
Based on both groups, the investigators developed the personal clinical and molecular mortality prediction index (PCMI) that incorporates the gender, lung functions and levels of one of the proteins, called MMP7, in the blood. Patients with a low PCMI were more likely to live more than 5 years while the median survival for patients with high PCMI scores was 1.5 years.
"This indicates that these blood biomarker levels are not just a reflection of current severity of the lung disease, but they are predictive of impending death," said lead author Thomas Richards, Ph.D., assistant professor of medicine and head of the Simmons Center biostatistics team.
"They have the potential to greatly improve our treatment strategies for IPF, in part by showing us which patients have the most urgent need for lung transplant, which is currently the only cure for the disease," added senior author Kevin Gibson, M.D., medical director of the Simmons Center.
"These findings provide proof of the concept of personalized medicine. " noted Mark T. Gladwin, M.D., chief, Division of Pulmonary, Allergy and Critical Care Medicine, University of Pittsburgh School of Medicine. "We can use a combination of biological and clinical markers to determine the very best care for each patient.
Drs. Kaminski, Gibson and colleagues have research projects underway to better understand how the biomarkers change over time.
The team includes Kathleen O. Lindell, Ph.D., R.N., and others at the Simmons Center and Pitt School of Medicine, as well as researchers from Centocor R & D in Radnor, Pa.
Study results will be presented by Dr. Kaminski at the IPF session of the Pittsburgh International Lung Conference on Personalized Medicine of Lung Disease at 2:30 p.m. on October 28 and 29 at the Holiday Inn Pittsburgh University Center.
The project was funded by the National Institutes of Health, Centocor, and the Dorothy P. and Richard P. Simmons Endowed Chair for Pulmonary Research.
Affiliated with the University of Pittsburgh Schools of the Health Sciences
Supplemental content provided by Healthwise, Incorporated. To learn more, visit www.healthwise.org
For help in finding a doctor or health service that suits your needs, call the UPMC Referral Service at 412-647-UPMC (8762) or 1-800-533-UPMC (8762). Select option 1.
UPMC is an equal opportunity employer. UPMC policy prohibits discrimination or harassment on the basis of race, color, religion, ancestry, national origin, age, sex, genetics, sexual orientation, gender identity, marital status, familial status, disability, veteran status, or any other legally protected group status. Further, UPMC will continue to support and promote equal employment opportunity, human dignity, and racial, ethnic, and cultural diversity. This policy applies to admissions, employment, and access to and treatment in UPMC programs and activities. This commitment is made by UPMC in accordance with federal, state, and/or local laws and regulations.
Medical information made available on UPMC.com is not intended to be used as a substitute for professional medical advice, diagnosis, or treatment. You should not rely entirely on this information for your health care needs. Ask your own doctor or health care provider any specific medical questions that you have. Further, UPMC.com is not a tool to be used in the case of an emergency. If an emergency arises, you should seek appropriate emergency medical services.
Pittsburgh, PA, USA | UPMC.com


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We are the hospital your pet would choose!
Jeffrey S. Bailey DVM
Dr. Bailey grew up here in Utah. He graduated from Weber High School and attended Utah State University where he earned a Bachelor of Animal Science degree. He was accepted to Colorado State University College of Veterinary Medicine where he earned a Doctorate of Veterinary Medicine. Dr. Bailey and his family moved to a small town in Southern California. He practiced small animal medicine and surgery there for 10 years eventually owning 2 small animal hospitals. In 2007 a chance to return to Utah came and he and his family happily took it. Dr. Bailey started a relief veterinary service covering for time off for local veterinarians. He eventually took a full time position at Quail Pointe Veterinary Hospital.
Dr. Bailey and his wife Monica have 4 children. They have more animals than can be named here including dogs, cats, horses, goats, chickens, rabbits and guinea pigs! They are a family of animal lovers. With kids and animals they are always busy with everything from baseball to soccer, violin to choir. They live on a small hobby farm in West Weber. The whole family is excited to be involved in delivery of veterinary care at the new hospital.


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I've been thinking a lot about words (that's a good thing, right?) and their effect. Unfortunately, the thing I'm working on just wasn't going to be ready in time for today, so I'm filling in with this number from Blue October. A bit bitter, but very powerful. Oh, one blatant F-bomb in here, you have been warned.
I hope you all have a great weekend!
Friday, April 26, 2013
Friday Music: Say It, Blue October
Labels: music
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