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Something Special is the perfect place to choose your wedding gown. We offer you something utterly unique: the experience of seeing the very best bridal fashion. Bespoke gowns are available from talented British designer Sandra Usude who has over 15 years experience, giving you a personal and caring service.
We are a well established company who pride ourselves on our professional and friendly service providing an extensive range of menswear for that special occasion. Our bridal department hosts some of the world's leading designers. Our stunning collection of bridal gowns, bridesmaids and accessories are unbeatable.
Set in spacious and elegant surroundings with an unrivaled choice of designer bridal gowns, bridesmaids, accessories, mens wear hire and much more. Our company is based on the belief that our customers' needs are of the utmost importance. Our entire team is committed to meeting those needs.
Providing an excellent collection of exquisite bridal gowns, an array of bridal accessories, and superb quality menswear.
You will enjoy our undivided attention as we discover, with you, the perfect wedding gown or occasion dress. When you find a bridal gown to match your heart's desire at Broughton's Bridals, then we will ensure that it fits perfectly.
Here at Paradise Grove, we specialise in providing Individually designed bridal gowns in all sizes and Bridesmaids in all sizes. We also have Men's and children's waistcoats and cravats available. Our aim is to make you feel as special as possible by creating the wedding gown of your dreams.
Star Dry Cleaning Leed is a Yorkshire based professional cleaning service provider. All work is carried out to the highest standard and is tailored to your exact requirements. All cleaners are fully vetted, so you can be confident that you will be provided with a decent, trustworthy and reliable cleaner.
We can confidently state that no other retail or hire company offers you the functionality, versatility and quality that we can. We do this because for 150 years our family business holds quality and service central to its core values.
At Big Day you will find everything you need in menswear for every formal occasion.
Your Stunning One-Stop Bridal Shop! Offering bridal wear, bridesmaids dresses, beauty treatments, bridal accessories, wedding cakes, mens formal wear and more!
Buy the finest Mens shoes and accessories for your wedding. Full ranges of top brands, including Loake, Barker, Grenson, Trickers, and Crockett & Jones.
We stock a huge range of wedding dresses, bridesmaid and evening dresses and suits from leading designers. We also offer accessories such as shoes, tiaras and veils.
The high quality kiltmakers owner, Gordon Nicolson, has over twenty-eight years experience in crafting kilts that are second to none. If you are after an original garment, any tartan is available in this popular store. For a totally unique piece, tartan design is also available to accommodate that extra special occasion.
Geoffrey (Tailor) specialise in traditional hand sewn made to measure kilts for men.
Howie Nicholsby's 21st Century Kilts offer a unique take, and are a fitting homage, to a traditional Scottish style. The use of original textiles, ranging from leather, gold and purple denim, camouflage, to pinstripe offer something different to those fond of this age old item.
The Kilt Hire Co began hiring & selling kiltsin 1991, in the town of Musselburgh, on the East coast of Scotland. Our reputation for keen pricing and commitment to excellent customer service quickly grew, with regular customers coming back time and time again to both hire and buy.
Denis Hope offers the best in quality and service for that special occasion. You will receive individual attention, professional advice and will be able to select from one of the most comprehensive collections of mens and boys hire wear available.
Are you looking for good quality suit hire? We offer so much more choice than you will find in the High Street Stores and being a family run business of course you will receive personal professional and unrivalled service. Our shops are totally dedicated to suit hire for all occasions in fact it's all we do.
We are a family run business situated on Kirkcaldy High Street. We understand that your wedding day should be perfect in every way. Therefore we try to make choosing your outfits as relaxing and stress free as possible. We have Wedding Gowns, Bridesmaid Dresses and Grooms Suits all under one roof.
We supply a range of bridal accessories from beautifully hand crafted tiaras, head dresses and veils to jewellery and shoes. Our bridal studio, based in Middleton, Manchester stocks an exquisite selection of bride and bridesmaid gowns, prom dresses, menswear and communion gowns.
Aults Menswear is located on Newport Street in Bolton, Greater Manchester and offers suit hire, formal hire and wedding suit hire. Established in 1891 we have many years of experience in the suit hire business and can help you find the perfect suit for any occasion.
Are you looking for the Wedding Gown of your dreams, Bridesmaid Dresses, Tiara, Veil, Bridal Shoes, Evening Wear, Prom Outfit or even Men's Formal Hire? If so Proposals should be your first port of call.
If you are looking for a stunning collection of wedding dresses in the Manchester area we are confident every customer will be spoilt for choice by our vast experience and fantastic bridal ranges, complimented by a great choice for mens suit hire, bridesmaids and accessories.
After the Big Day, what better way to capture your memories than to have everything expertly cleaned ready for storage. We offer a totally bespoke service to suit your needs and budget. We also carry out any small repairs, for example to hems and trains.
Granada Dry Cleaners, a privately-owned family-run business, was established in 1956 and is still to this day run by the original owners. We are based in the City Centre of Manchester and have a vast amount of experience in providing all aspects of dry cleaning.


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Say what you want about the TEA PARTY...
… but I don't recall any video of doctors handing out fake sick-notes so they could protest.
Wisconsin Teacher Unions are shooting themselves in their own feet. No one will back their insistance at benefit-collective-bargaining when they fake sick days instead of teaching kids.
Unions, in this case at least, are not all for the children; they are for the dollars. Not that there's anything wrong with it, because that's what the free market is all about. But in a free market, there aren't union strikes (or the threat of them) that influence those dollars.
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Karen Corcoran-Walsh will offer her knowledge in documentary on flakka
Karen Corcoran-Walsh, owner of Inspirations for Youth and Families teen rehab and the Cove Center for Recovery adult drug treatment center was interviewed recently by A Plus Pictures, for a documentary on flakka, to be aired on either Netflix, HBO, MTV, or Lionsgate Films. One of the most pressing questions involved the recent acquittal of a Miami man who played a supporting drug role in the first-ever flakka trial.
Watch the interview
Here are the excerpts from the interview
A Plus Pictures: What type of drugs does Inspirations for Youth and Families treat today?
Karen Corcoran-Walsh: Most of the street drugs that are in our communities today. The range of drugs would be anything from Special K, flakka, other synthetic drugs, amphetamines, bath salts and other drugs like Rave drugs, ecstasy and so on.
What are the characteristics of a teen using flakka?
KCW: The characteristics would be more of a risk taker, because flakka is a drug that is not commonly used with teenagers and the signs of flakka use would be a teenager that would go beyond the scope of the easily available drugs or the more commonly used drugs.
What is flakka?
KCW: It's Alpha PVP, which is an amphetamine-like meth and characteristics like that. It's comprised of cathinones which gives the illusion of a very happy state.
What are the signs of someone using flakka?
KCW: Well the signs of someone under the influence of flakka is someone who would present very erratic, sweating profusely, possibly appearing as if they had a fever. They are going to be extremely happy, extremely abnormal in their presentation. They would possibly say things that wouldn't make sense. They would rattle on in their sentences and possible be hyper-verbal and they may be imaging people chasing them. There is a lot of paranoia that goes with someone under the influence with flakka. They can be dangerous at times because their behavior is unpredictable and if they are in fear of their life or what they would envision someone chasing them and threatening them and they can retailiate although it is just their imagination. So this can happen very quickly facing someone under the influence of flakka.


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SAN JOSE, Calif. - Hugo Campos has a small computer buried in his chest to help keep him alive. But he has no idea what it says about his faulty heart.
SAN JOSE, Calif. � Hugo Campos has a small computer buried in his chest to help keep him alive. But he has no idea what it says about his faulty heart.
All the raw data it collects, especially any erratic rhythms it controls with shocks, go directly to the manufacturer. And some of it later gets sent to his doctor.
But Campos is fighting to see the data his body produces, and his David-and-Goliath campaign puts him on the leading edge of what�s called the �e-patient movement� � �engaged, equipped and enabled� � that seeks to harness data so that patients can learn more about their bodies.
�It�s mine. I paid for it. It�s in my body,� said the 45-year-old, who since his heart-related collapse four years ago has devoted himself to accessing the electronics of his tiny defibrillator.
The information could help him take control of his health, said the graphic artist. Already, he discovered � using an online spreadsheet accessible from his iPhone � that caffeine and Scotch trigger irregular heartbeats.
But it would be far better to have raw, real-time data, he said.
Federal law entitles patients to easy access to their health records, including X-rays and pathology reports.
But implanted-defibrillator data are different. The information stays with manufacturers, who use it to monitor and improve their products. And it comes in a format not easily understood. Patients can get only interpreted data, not the raw data.
Each year, hundreds of thousands of Americans are implanted with small battery-powered electrical-impulse generators, such as pacemakers, loop recorders and cardiac defibrillators.
The devices are critical for people such as Campos, whose irregular heartbeat threatens cardiac arrest. The devices also wirelessly transmit data to bedside monitors and then over a telephone line to the manufacturers.
Much of the collected data are diagnostic. But these devices also collect huge amounts of proprietary information, such as wiring breakdowns, battery voltage and the time it takes to release a shock.
But Campos� campaign has a professional supporter.
�It is embarrassing to leave our patients in the dark, by design or technological necessity,� Dr. David Lee Scher, a former cardiac electrophysiologist who founded DLS Healthcare Consulting, wrote on his blog.
He cautions that the data are very technical, even for physicians, and often irrelevant. He urges patients and physicians to work together on a solution.
To learn how to understand the device and its data, Campos earned a certificate from the Arrhythmia Technologies Institute and bought 19 used devices on eBay.
Calls and emails deluged Campos after an online video of a speech he gave in November went viral, and he has testified before the U.S. Food and Drug Administration.
He also has started a blog and founded an online user group.


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Current PayPal Pledges:$2,591
Our rewards system is simple: All tiers include the rewards from previous tiers, with 3 exceptions:
The Kickstarter version of the game will be released for Windows.
Now that we have met our Porting stretch goal, we will be giving out Wine wraps at the PC release then upgrade Mac and Linux users to the native versions when the engine ports are ready. This is for DIGITAL COPIES, if you're a Mac user and would like to see physical Mac copies in our store, let us know!
Android and iOS copies cannot be offered as rewards due to rules relating to their distribution (which are beyond our control).
Mage's Initiation is a Role-Playing / Adventure Game hybrid, very similar in style and execution to Sierra On-Line's classic Point--Click
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and King's Quest series. It maintains all the charm of classic and timeless adventure games of yesteryear while adding 21st century innovation to the mix - like multiple game interfaces, and a free-range magical combat system!
We're all very big fans of the adventure genre here at Himalaya Studios, and we feel that Sierra's games really hit their peak in the early 90s. We're working hard to provide a nostalgic experience, reminiscent of that golden era of 2D Sierra adventures circa 1993-1994.
Mage's Initiation has a medieval / fantasy setting and it features multiple playable character classes, spell-casting, and an open-field magical combat system, complete with equippable items and monster loot drops!
In the quiet, provincial realm of Iginor, evil is stirring. Dangers abound on all sides: the forest, wastelands, and even the once-protective mountains look to the tiny town with glaring eyes. Into this, a young, would-be Mage sets forth to prove himself worthy of joining the ranks of his brethren. This is his journey. A Mage's Initiation.
You assume the role of D'arc, a sixteen-year-old Initiate who must complete a trio of tasks set by his Mage Masters. Journey through the medieval-styled realm of Iginor. Brave a goblin-infested forest. Navigate a vast lake to encounter an evil so pure, not even beauty can disguise it. Ascend to the peaks of Flyteria, a valley of winged warriors once dedicated to protection of the human town.
Succeed and D'arc shall take his place among his fellow Mages.
Fail and nobody shall remember his name.
In-game screenshots from the current alpha build of Mage's Initiation.
Earth, Air, Fire, Water... the choice will affect your game-play. From combat strategy to spells and puzzles, each class provides a unique set of challenges. With four ways to live (and re-live) the adventure, you're sure to discover great replay value!
A management system is the way in which an organization manages the inter-related parts of its business in order to achieve its objectives. These objectives can relate to a number of different topics, including product or service quality, operational efficiency, environmental performance, health and safety in the workplace and many more.
The level of complexity of the system will depend on each organization's specific context. For some organizations, especially smaller ones, it may simply mean having strong leadership from the business owner, providing a clear definition of what is expected from each individual employee and how they contribute to the organization's overall objectives, without the need for extensive documentation. More complex businesses operating, for example, in highly regulated sectors, may need extensive documentation and controls in order to fulfil their legal obligations and meet their organizational objectives.
ISO management system standards (MSS) help organizations improve their performance by specifying repeatable steps that organizations consciously implement to achieve their goals and objectives, and to create an organizational culture that reflexively engages in a continuous cycle of self-evaluation, correction and improvement of operations and processes through heightened employee awareness and management leadership and commitment.
The benefits of an effective management system to an organization include:
MSS are the result of consensus among international experts with expertise in global management, leadership strategies, and efficient and effective processes and practices. MSS standards can be implemented by any organization, large or small.
Audits are a vital part of the management system approach as they enable the company or organization to check how far their achievements meet their objectives and show conformity to the standard.
In order to help the auditing related to these standards, ISO has released
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providing specific guidance on internal and external management system audits.
Many ISO management system standards have the samestructure [PDF] and contain many of thesame terms and definitions. This is particularly useful for those organizations that choose to operate a single (sometimes called "integrated") management system that can meet the requirements of two or more management system standards simultaneously.
Standards are developed by the people who need them – that could mean you.
Technical committees include experts from both standards and industry and these experts are put forward by ISO's national members. If you want to help shape future standards in your field, contact your
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Certification to management system standards is not a requirement. You can benefit from implementing these standards without being certified to them.
However, if you are looking to get certified to one or more of our management system standards, then you need to get in touch withan external certification body.
That's because ISO does not perform certification .
Read more about
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Certification is not the only way to show conformity to standards. Read more about conformity assessment .
Find out how many certificates to ISO management standards are awarded in each country, each year.
Useful to know when it comes to conformity.
Post written by
Gerry Valentine
Sydney Evan Pave Diamond Love Single Stud Earring yAbDECim
is an executive coach and public speaker with 25 yrs. Fortune 100 experience. He advises business leaders and entrepreneurs.
"What does it mean to be resilient?" That's the question one reader asked in response to my
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on Forbes. It's a great question.
The idea of "resilience" has entered the mainstream of life. Well-known researchers like Brene Brown and Angela Duckworth have published on the topic. But a lot of people don't understand what resilience is.
There's a misinterpretation that resilience is about being fearless, being tough or just being able to pick yourself up by the bootstraps. These misperceptions are especially prevalent in business circles. That's a big problem because this way of thinking can actually make business leaders less resilient. Let's clear that up.
Fear, Adversity AndParalysis
The easiest way to understand resilience is to first understand how it gets derailed, and that's often through a destructive process I call the "fear, adversity, paralysis cycle." Here's how it works. When faced with adversity, we all feel fear. It's a fear that we won't be able to overcome the adversity. That's perfectly natural. The problem develops when the fear becomes a paralysis that prevents us from responding productively to the adversity. And the paralysis always leads to even more adversity -- either the original adversity worsens or a new one arises.
For example, Eastman Kodak
filed for bankruptcy
in 2012 -- some people would say because of the digital camera. But here's something many people don't know: The digital camera was
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who worked for Kodak back in 1975.
So, what happened? The cycle happened. When faced with the disruptive technology of digital photography, Kodak's leaders -- people who only understood the film business -- allowed their fear of change to trigger a paralysis that prevented them from leveraging their own invention. By the time Kodak came around, the competition had an insurmountable lead.
Examples of fear and paralysis are all around us, and most people don't notice them. It's the executive who's terrified of change and clings to the past. It's the entrepreneur who is so frightened that she micromanages everything and paralyzes her company. It's the company with employees who are so caught up with blaming and finger-pointing that it can't innovate.
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Darcy DeLoach
Dr. DeLoach earned her Bachelor of Music in Music Therapy, Master of Music in Music Therapy and Doctor of Philosophy in Music Education with Emphasis in Early Childhood and Medical Music Therapy from the Florida State University. Before joining the University of Louisville faculty, Dr. DeLoach taught at Florida State University. She is a Fellow of the National Institute of Infant and Child Medical Music Therapy and participates in trainings on a continuing basis.
Dr. DeLoach has worked clinically in medical, hospice, special education, and battered women and children shelter settings. Her research focuses are neonatal intensive care unit music therapy interventions, music therapy for procedural support, and early childhood development including children with autism spectrum disorders. Dr. DeLoach received the South Eastern Region American Music Therapy Special Recognition Award for Outstanding Research Contributions. She presents and lectures nationally and internationally to music therapy, music education, and medical audiences.
She is the past chair of the board of directors for the Certification Board for Music Therapists and currently serves as co-chair of the Autism Task Force for the American Music Therapy Association and on the Editorial Board for the Journal of Music Therapy. She has served as an outside reviewer for the Journal of Autism and Developmental Disorders, New Zealand Journal of Music Therapy, and the Journal of Neonatal Nursing.


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Hilary Duff Hits the Beach in a Bikini After Calling Out Body Shamers
Hilary Duff isn't afraid of what body shamers have to say!
The 29-year-old actress hit the beach in a bikini on Friday afternoon (August 4) while on vacation in Wailea, Hawaii.
Hilary was joined by her five-year-old son Luca (not pictured) as they enjoyed some fun in the sun.
Earlier that day, Hilary took to her Instagram to call out people who had some not-so-nice things to say to in response to photos of her in a one-piece swimsuit.
After sharing her empowering message, she posted a selfie enjoying some fresh pinapple juice!
It looks like Hilary is continuing to enjoy her vacay no matter what body shamers have to say!
FYI: Hilary is wearing L'PORT bikini bottoms.


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The Lost Continent
Mia the Mage
Main Wiki
Our Adventures
Memorable Quotes
Mia, known as "Mia the Mage" to some parts of the criminal element of Walsh, was the lover and partner in crime of Fligg Errol. She often used her magic to conceal the evidence of Fligg's crimes; most notably she helped him rape and murder Challa Redroot. Overconfidence in her skills as a cleric of Wee Jass led to Mia's death in 995 W. when she was stabbed and then melted by acid after challenging Ianto in an altercation outside of The Gladiator.


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Operational Excellence.
Avalign has worked in partnership with OEM customers for more than 30 years to provide unmatched value in the development and manufacturing of precision medical instruments. We are focused on developing long-term strategic relationships and are intent on providing our customers with exceptional products and value-added services. Attention to detail and superior quality standards contribute to a highly responsive, technologically advanced source for manufactured instruments. Our precision machined instruments provide interoperability between instruments and implants, between instruments and between components within assemblies.
Dedication and Commitment.
Engineering expertise combined with manufacturing capabilities enable us to provide our customers with exceptional medical solutions that improve the quality of life for their patients. Each customer has a specific Product Engineer dedicated to their project. Our Product Engineers work jointly with customers in all phases of product design and manufacture. From "Concept through Packaging" to "Design for Manufacturing," our engineers have a proven track record of success and have the ability to take on development projects both large and small in scope. This approach helps our customers shorten their product development cycles, reduce production lead times and reduce their design and manufacturing costs with the end result being a successful product launch.
Learn more about Flex-Shaft Technology
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Manufacturing Capabilities.
Avalign Instruments & Implants continually evaluates and invests in state-of-the-art technologies to meet our customer's manufacturing needs and quality expectations. In satisfying their complex requirements and inspection criteria, we utilize many of the latest manufacturing and inspection technologies, including:
- 4- and 5-axis CNC Mills
- Citizen Swiss Turning Centers
- Mori Seiki Mill Turns
- Wire EDMs
- Gun Drills
- Coordinate Measuring Machines (CMMs)
- OGP Vision Measurement System
- Ultrasonic Cleaning, Passivation and Laser Marking
Other capabilities include welding, polishing, heat treating, coating, electropolishing, anodizing, assembly and final packaging.
Development resources are valuable and often limited. Avalign Instruments & Implants employs proven, streamlined, cost-effective methods to launch innovative devices to the end-user market.
Click here to contact Avalign Precision Machined Instruments
8727 Clinton Park Drive Fort Wayne, IN 46825 Telephone: (800) 255-4576 Fax: (260) 482-9782


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Buzzfeed often creates headlines that compel us to click on them. Have a look at these headlines from the last few weeks on the site:
A Mountain Biker Had A Seven-Week-Long Erection After Injuring His Penis
The Couple Who Asked The Internet To Name Their Daughter May Be Regretting It About Now
There Is An App Which Will Quit Your Job For You
15 Whimsically Surreal GIFs To Get Lost In
Stunning Ice Sculptures Grow In The Coldest Weather
What Does Your Favorite Breakfast Food Say About You?
We feel compelled to click the link and discover why mountain biking is related to penis injuries. We really want to know what the daughter has been named. WHICH app will quit my job? Why are the GIF's surreal or the ice sculptures stunning? And how is my personality related to breakfast foods?
Compelling headlines grab our attention. Numbers in headlines pique our curiosity. Strange multiples of numbers are more attractive to us than 'normal' numbers. A title containing the number 11 titles with 5, 10 or even 15.
We want to discover what the extra number gives us (or, in the case of 9 whimsically surreal items, what the missing item might be).
Superlatives are also useful. The use of 'best, worst, most, least, awesome, dreadful, surreal, stunning, favourite, hated etc.' will get more clicks than titles and subtitles that are missing these words.
Clever body text is important too
Use of the right compelling phrases within the body text will also determine whether success eludes you. Researchers Tanushree Mitra and Eric Gilbert at Georgia Institute of Technology in Atlanta looked at the way that pitches for kickstarter funding.
The team looked at a list of 45,815 Kickstarter projects, scraped the data and found that some phrases really helped to get funding. These are the top 14 phrases likely to receive funds:
The phrases least likely to receive funding are:
Images are screenshots from the paper Phrases that Predict Success on Kickstarter
The phrase "even a dollar" throws up some interesting options according to the paper. It appears in the dataset where projects were not funded.
The visualization shows that the most likely phrases are even a dollar short, even a dollar will, even a dollar can, perhaps be perceived as "grovelling for money".
On the positive side, the phrase "pledgers will receive" and variations on this theme appear most often in projects that are successful in receiving enough money to complete their kickstarter project.
The team also noted that forward looking phrases were more likely to be successful at getting funding than non forward looking phrases.
We like to think we will get something in returns for our pledge, we want to think that the object we covert is rare, exclusive, special, one-off or time limited offer.
People asking for funding just need to tap into that desire…
PS – 6 was not the number of attention grabbing words – it was just a better number than 10
Image: By Tkgd2007 (Made by myself in Illustrator) [Public domain], via Wikimedia Commons
Eileen Brown is a social media strategist and consultant at Amastra, a columnist at ZDNet and author of Working The Crowd: Social Media Marketing for Business. Connect with Eileen on Twitter and Google+ or contact her to find out how she can elevate your brand and help your business become more social.


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APA (Old Order Amish; Eastern Pennsylvania)
Inheritance: autosomal recessive
Genes: CYP11B2
Aldosterone deficiency I
CMO I deficiency
Aldosterone deficiency due to defect in steroid 18-hydroxylase
Salt wasting
Failure to thrive
Growth retardation
Clinical Characteristics
General description (for patients):
This condition leads to salt wasting and electrolyte imbalance in children beginning as early as several weeks of age. If not treated, severe dehydration may result. There may be increased susceptibility to infection.
Medical description:
This adrenal cause of salt wasting results from a defect in one of the steps of aldosterone biosynthesis, the 18-hydroxylation of cortisone (B) to 18-hydroxycorticosterone (18-OHB). The decrease in aldosterone can lead to hyperkalemia, hyponatremia, and metabolic acidosis resulting in failure to thrive and growth retardation. Severe dehydration and intermittent fever may also occur. The ratio of corticosterone to 18-OHB is elevated, just the reverse of an allelic disorder, CMO type II, in which the next enzyme in the cascade, 18-oxidase, is deficient. Those patients surviving infancy have a milder disease as another mineralocorticoid, 22-deoxycorticosterone, aids in maintaining electrolyte balance.
A mutation in the CYP11B2 gene on chromosome 8 (8q21) causes this disorder via a defect in the corticosterone methyloxidase enzyme. The same gene also codes for steroid 18-hydroxylase (P-450C18). This is an autosomal recessive disorder which has been found among the Lancaster County, Pennsylvania, Amish secondary to a five base pair deletion in the CYP11B2 gene.
Mineralocorticoid supplements have been reported to be helpful. Over time the new endproduct, 11-deoxycorticosterone (DOC) is accepted as the new mineralocorticoid diminishing the need for exogenous mineralocorticoid.
Variable as a result of variations in mutations. Few families have been reported.
Ancillary treatments and support:
Electrolyte monitoring.
Specialists and speciality centres:
Pediatricians, endocrinologist.
Mitsuuchi, Y., Kawamoto, T., Miyahara, K., Ulick, S., Morton, D.H., Naiki, Y., Kuribayashi, T., Toda, K., Hara, T., and Orii, T., Yasuda, K., Miura, K., Yamamoto, Y., Imura, H., and Shizuta, Y.: Congenitally defective aldosterone biosynthesis in humans: inactivation of the P-450C18 gene (CYP11B2) due to nucleotide deletion in CMO I deficient patients. Biochem. Biophys. Res. Commun. 190: 864-869, 1993. PubMed ID: 8439335
Peter, M., Fawaz, L., Drop, S.L.S., Visser, H.K.A., and Sippell, W.G.: Hereditary defect in biosynthesis of aldosterone: aldosterone synthase deficiency 1964-1997. J. Clin. Endocr. Metab. 82: 3525-3528, 1997. PubMed ID: 9360501


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November 22, 2012 11:32 ET
TORONTO, ONTARIO--(Marketwire - Nov. 22, 2012) - Striking contract course instructors, teaching assistants and continuing education instructors at the University of St. Michael's College, members of Unit 4 of Local 3902 of the Canadian Union of Public Employees (CUPE 3902-4) have reached a tentative agreement with their employer.
"We're very pleased to inform St. Mike's students and the broader University of Toronto community that we have successfully negotiated a first collective agreement that is fair to our members, fair to St. Mike's and strengthens quality post-secondary education," said Tadhg Morris, a member of Unit 4's bargaining team and a Celtic Studies instructor at St. Mike's.
Details of the agreement are not being released until Unit 4 members have had a chance to review it today. A ratification vote will follow soon after.
"The bargaining team was creative and we were able to break the impasse and achieve a fair settlement, without any intervention from the province," said Abe Nasirzadeh, Chair of CUPE 3902.
"I think we've demonstrated-not just to St. Mike's and the University of Toronto, but also to the provincial government and others who are trying to interfere with free collective bargaining-that the system works. More to the point, the system works best when employers and employees sit down and negotiate agreements free of interference and the threat of legislation," he added.
Abe NasirzadehCUPE 3902 Chair647-236-3902Kevin WilsonCUPE Communications416-821-6641
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Trucks & Cars
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Next Day Service Available
Compu de Sign located at 3719 John F Kennedy Blvd in Jersey City, NJ services vehicles for Truck Body Repair. Call (201) 217-0039 to book an appointment or to hear more about the services of Compu de Sign.
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Since 1990 the company has been providing Graphic Arts And Related Design.
Compu De Sign can be found at John F Kennedy Blvd 3719. The following is offered: B2B Signage. The entry is present with us since Sep 9, 2010 and was last updated on Nov 14, 2013. In Jersey City there are 7 other B2B Signage. An overview can be found here.


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Raji is a force
Expect the man who provided the Packers the NFC championship-winning touchdown to make the most difference in Super Bowl XLV.
Packers nose tackle B.J. Raji, whose fourth-quarter interception return for a touchdown against the Bears paved the road to Dallas, can't wait to exploit perhaps the Steelers' only weakness. The Steelers likely will be without rookie Pro Bowl center Maurkice Pouncey, who has a high ankle sprain and possible fracture. Replacement Doug Legursky could make his first start at the position.


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The annual Halloween Spook House sponsored by the Lisle Park District will be open Wednesday and Thursday in the Lisle Park District Community Center, 1825 Short St., Lisle. The friendly monster hour, for children 3 to 9, will be held from 5 to 6:30 p.m., followed by a costume parade. The spook house will reopen for those 10 and older at 7 p.m. Admission to the spook house is $1.
A pumpkin-carving contest for 6- to 12-year-olds will be held at 3:30 p.m. Tuesday in the Lisle center.
The Lisle Lions will hold their annual ''Goblin Burning'' bonfire at dusk Thursday in Community Park, across from the center.


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EAST RUTHERFORD, N.J. (AP) - Josh Scobee kicked a 21-yard field goal as time expired to give the Jacksonville Jaguars a 24-22 victory over the New York Jets on Sunday.
With the Jaguars facing second-and-6 from the 10, Maurice Jones-Drew took a handoff up the middle and went to a knee at the 1 to give Jacksonville first and goal with just over a minute left.
New York had no timeouts left. David Garrard knelt the ball twice, giving Scobee the opportunity to kick the game winner for the Jaguars (5-4).
It was another devastating loss for the Jets (4-5), who came out of their bye-week break making the same types of mistakes that plagued them in the first eight games.
New York has dropped five of its last six.
(Copyright 2009 by The Associated Press. All Rights Reserved.)


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Tenants who refuse to let council engineers into their homes to check their heating could go to prison.
Residents in the North East have been warned that they could face two years in jail. By law gas heating in rented homes must be serviced every 12 months because of the carbon monoxide danger.
Last week a Northumberland County Court judge granted Castle Morpeth Borough Council an injunction against a tenant and threatened a two-year sentence if the tenant refused access.
Castle Morpeth director of community and customer services Trevor Walker said these tenants were putting themselves and the council at risk.
He said: "We can tolerate it for so long but when it gets to two years without the system being serviced, we decided we had to do something, and court action is the ultimate step."


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Developers / Re: Supporting the ACT Solutions ZCU201 USB Z-wave Interface« on: February 03, 2008, 10:19:38 am »
Thanks a lot, Hari! Since those old ACT ZWave controllers aren't sold anymore, this is pretty important. I just got one of the controllers and we're going to test it and try to make it work for the 0710 release.You are welcome. Btw, the intermatic ha22 (04FC0204) should also work with this driver. When you modify the ZWave device template please don't forget to also add the two Seluxit usb id's (16c006eb, 1d6f0001).
I don't know if all fixes are in the lmce branch yet (one file got updated in the trunk, ListAvailableSerialPorts.sh is still missing, see notes on that issue: http://mantis.linuxmce.org/view.php?id=3823).
feel free to contact me if you need any assistance.
best regards,
Greetings. I assume the reference to the seluxit devices relates to the kernel driver at http://svn.charonmedia.org/svn/vendor/spcp8x5/ringbuf.c ?
In any case: the driver compiles and loads with 2.6.24, and I have taken the liberty to add the driver to http://www.linuxdriverproject.org/twiki/bin/view/Main/OutOfTreeDrivers
Now I just need to read up on zwave to figure out what to get and what to avoid...


text: http://omegle.com I saw this somewhere and thought hey wtf, ill try it out. Basically you click the chat button, and get connected with a total stranger. Ive done it like 9 times and none were a bot, and were actually really nice. Now im SURE you can chat for 2 mins, then shift the convo to something your promoting, and pounce on them with your aff link. Ive already directed 2 convo's towards weight loss and 1 towards "that wierd berry thing oprah was talking about called acai" Check it out


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A group asking the Boulder Valley School District to create an owl preserve on the Twin Lakes property in Gunbarrel that's being eyed for an affordable-housing development plans to speak at Tuesday's school board meeting.
The group, which includes two Boulder Valley students who recently completed a documentary called "Home for the Owls," wants the school district to maintain its 10-acre property as open space and owl habitat instead of using it for affordable housing.
The county is proposing building an affordable-housing development on its own 10 acres and the school district's 10 acres.
The school board meeting is scheduled to start at 6 p.m. Tuesday at the Boulder Valley Education Center, 6500 E. Arapahoe, Boulder.


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Yakuza: Dead Souls launch trailerPosted Mar 13, 2012 8:15am PDT - 4,942 views
The Japanese Ground Self-Defense Force shuttles in to Kamurocho to take on a zombie outbreak, but are soundly defeated. Now, only four gun-wielding heroes with ties to the yakuza can save the village.
Yakuza: Dead Souls pre-order trailerPosted Mar 12, 2012 9:40am PDT - 7,716 views
Pre-order Yakuza: Dead Souls for access to an ample helping of exclusive weapons, costumes, and missions.
Yakuza: Dead Souls mini-games trailerPosted Feb 16, 2012 10:43am PST - 4,200 views
Killing zombies is a dirty, mind numbing experience. Refresh your senses in plenty of Yakuza: Dead Souls mini-games!
Yakuza: Dead Souls 'Story' TrailerPosted Jan 18, 2012 3:23pm PST - 4,489 views
The series swerves into undead territory with Yakuza: Dead Souls, and this trailer lives up to its caption that reads "should you ever find yourself in a Tokyo overrun with zombies, it's good to have friends… especially friends with shotguns. "
Yakuza: Dead Souls 'Characters' TrailerPosted Dec 02, 2011 11:38am PST - 7,927 views
Kamurocho is in ruins, and zombies roam the streets after the Japanese Ground Self-Defense Force fails to contain the outbreak in Yakuza: Dead Souls.
Yakuza: Dead Souls 'Announcement' TrailerPosted Oct 05, 2011 8:33am PDT - 10,593 views
The Japanese gangster series' undead spin-off comes westward in March 2012.


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I'd pick her up any day of the week. She's so eager to please and looks like she's having so much fun.
Featuring: Jewel Styles and Peter Delmar
Date: March 11th, 2013
Photos: 40
Jewel knows that it's nice to be nice! This guy didn't have to stop and pick Jewel up from the side of the road. She knows that. He probably had important places to be. And he didn't have to drive her to where she needed to go. But he did. He was nice, and the thing is, Jewel is nice, too. And she wanted to pay him back for his kindness by sucking and fucking his cock! They say you get what you give, so make sure you give good! "I'm a big believer in treating others the way you want to be treated," Jewel said. "That's why I give guys the first-class cock treatment. If I lavish their dick with attention, then they are very likely to give my pussy the kind of pleasure it needs." Jewel gets all the pleasing she can handle with this guy's hot beef injection. See it for yourself in the DVD Pickin' Up Pussy 4! "His dick felt so big in my little hands, and it felt even bigger in my little pussy! I was so turned on I even did a split over his cock." We helped Jewel to fulfill one of her hot fantasies.
What Members are saying about this update...
May 05, 2016
September 04, 2014
don't wait any longer, give your dick a treat and come to Jewel, incredibly hot
horny bitch.
May 19, 2013
Clearly knows what to do with a dick. Those hot pants are a hell of a turn on.
She can come to my motel room anytime.


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SACRAMENTO- Following an unprecedented step by the Trump Administration to weaken federal vehicle fuel efficiency standards, California State Senate Democrats have written a letter to California Attorney General Xavier Becerra offering strong support for decisive legal action to intervene on the state's behalf.
The Trump Administration on Wednesday issued an executive order reopening review of the federal Corporate Average Fuel Economy (CAFE) Standards finalized in 2012 under President Obama. These standards, modeled after California's pioneering tailpipe emissions standards (AB 1493, Pavley), have helped save Americans billions of dollars in avoided fuel costs while reducing toxic air pollution.
"Weakening fuel efficiency standards amounts to a taxpayer giveaway to oil companies," Senate Leader de Leon said. "Why does President Trump want Americans to give more of their hard-earned money to ExxonMobil and OPEC?"
The 22 Democratic Senators offered their support to Attorney General Becerra's intervention in a federal suit against the Environmental Protection Agency by the Alliance of Automobile Manufacturers, announced in coordination with the President's executive order, challenging the feasibility of the current fuel efficiency standards.
Multiple reports suggest the Trump Administration may also attempt to withhold California's waiver under Section 209 of the Federal Clean Air Act to pursue air quality standards that are more stringent than federal law requires.
Even before the federal Clean Air Act was enacted in 1970, California had already begun its pioneering efforts to reduce smog and air pollution from the transportation sector. Congress and the President acknowledged and supported California's efforts by enacting Section 209 of the Federal Clean Air Act, which grants California unique authority to set its own vehicular pollution control standards if granted a waiver by the US EPA.
Over the past 50 years, under both Republican and Democratic administrations, over 145 waivers have been granted to California to pursue tougher standards, in recognition of the fact that our state continues to have regions suffering the worst pollution in the country.
"California's right to pursue strong clean air standards is explicitly granted by federal law," Senate Leader Kevin de León said. "If this administration has a problem with that, they can go through Congress or see us in court."
"Trump's Administration seems on the verge of Making America Polluted Again," said Senator Bob Wieckowski (D-Fremont), chair of the Senate Environmental Quality Committee. "Rather than raising the bar to challenge America's innovators by putting their ingenuity to work building 21st century vehicles, he's waving the flag of surrender on climate change, and guaranteeing more people will suffer from dirtier air, higher asthma rates and respiratory problems."
Environmental Protection Agency Administrator Scott Pruitt has worked closely with the fossil fuel industry throughout his career to undermine critical environmental protections. The relationship is so close that Mr. Pruitt's office has been known to directly copy industry language into official agency correspondence.
Press Release: California Leaders Blast Cynical Ploy by Trump Administration, Automobile Manufacturers to Roll Back America's Car Pollution Standards
Senate Unveils California Environmental Defense Act, Public Lands and Whistleblower Protections
New York Times: Trump to Undo Vehicle Rules That Curb Global Warming
Washington Post: EPA to pull back on fuel-efficiency standards for cars, trucks in future model years
New York Times: The Pruitt Emails: E.P.A. Chief Was Arm in Arm With Industry
Statement by California Senate Leader on the Confirmation of EPA Administrator Scott Pruitt
VIDEO (Senate Democrats): Conversation with former EPA Administrator Gina McCarthy
#PreserveCA #ActOnClimate


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Michael Tsai has released version 2.4 of SpamSieve, his Bayesian spam filter for Apple Mail, Microsoft Entourage and Outlook 5, Emailer, Eudora, GyazMail, Mailsmith and PowerMail. This update provides a universal binary to the Apple Mail plug-in, which will allow SpamSieve users to run Apple Mail on Intel Macs without resorting to Rosetta.
Other changes include accuracy improvements in the Bayesian filter engine, heuristics for detecting "phishing" scams, the ability to file Apple Mail messages in different mailboxes based on their "spammines," support for Habeas headers, a change to the Software Update alert that keeps it from interfering with spam filtering, and more.
This is a free update for registered owners of SpamSieve. The full software is US$25 and requires Mac OS X v10.2.8 (v10.3.5 recommended).


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As we enter the new year, we want to share some accomplishments at Orange County Animal Services during 2017. A number of notable innovations continued to buld on our successful effort over the last decade to reduce animal intakes and create a robust rehoming program for healthy and sound animals. But they all ultimately depend upon the strong support of county residents and their diverse communities.
Animal Services continues to seek to eliminate the need for euthanasia as a means of population control in Orange County. Increasingly, we have also concentrated our efforts on wellness, enrichment, and ensuring that cats as well as dogs have their varied needs meet during their shelter experience. Also, as a county agency with responsibilities in our municipalities and unincorporated areas, Animal Services seeks to be prepared for natural disasters as well as to provide more field and sheltering services.
Against this broader backdrop, we want to share the following highlights:
Growing spay and neuter: Thanks to a grant from the Margo T. Petrie Foundation, we have been able to make free spay and neuter services for cats and dogs available to more county residents than ever before. They are now available to residents with a household income of up to 400 percent of the federal poverty level as well as people on public assistance. In this way, we intend to continue to drive down the rate of pet reproduction, animal admissions, and the euthanasia of animals for whom there is no shelter space or homes.
Redefining adoptable animals: Through our veterinary health care program, we have developed and strengthened initiatives to treat heartworm in dogs and ringworm in cats. We have also made changes in our management of kittens, which have helped to control the incidence and spread of upper respiratory infections within the feline shelter population. These and other health care changes, made possible by reduced shelter numbers resulting from spay and neuter efforts, have meant that many ill animals are now being treated and adopted rather than euthanized.
Generator Installation: Late in the year, a much awaited diesel-powered generator was installed as part of a broader process of capital improvement in county facilities. The size of the generator is sufficient to power the entire Animal Services Center. It operates with an automatic transfer switch and smart digital controls which enable it to be exercised weekly. In addition to enabling Animal Services to operate in all areas of service when there is a loss of electricity, the generator ensures that the shelter itself remains minimally comfortable during winter or summer months in the face of inclement weather, hurricanes, or other incidents requiring an emergency response.
Shelter cat enhancements: In 2017, we concluded our effort to see that our cat enclosures meet the latest housing recommendations formulated by the Association of Shelter Veterinarians. Specifically, we installed portals in stainless steel cat cages throughout our admission and holding areas to allow adjacent cages to be transformed into double compartments (in the same manner we had previously done in our adoptable cat room). These portals not only increase space, but they also benefit cats by allowing food, bedding, and litter to be kept separate. In this and other ways, they helped to reduce stress and improve the health of shelter cats.
Kitten fosters: Our veterinary health care staff created a foster program for kittens too young to be spayed or neutered and adopted upon their admission. More often than not this is the case during "kitten season," the months from spring through early winter when there is an incessant influx of pregnant cats and kitten litters. Foster homes are an ideal setting for their socialization, and their home care has helped tremendously in stemming both the incidence and spread of upper respiratory infections among felines.
Public animal art: Along with the Animal Services Advisory Board, staff partnered with the Orange County Arts Commission to support "Calypso Cat," a hand-made steel sculpture by artist Mark Elliott, which now greets visitors at the entrance to Animal Services. A figurative feline was favored because of our ongoing concern with more proactively and humanely managing cats in our county, as reflected in our five-year strategic plan for free roaming cats. At the same time, adding more public animal art – given the prior acquisition of Mike Roig's "Sit" and "Stay" sculptures – was greeted as a tremendous opportunity to express the rich and varied bond between people and animals.
All of these accomplishments are made possible by truly outstanding community support. Without support from residents and elected officials, stakeholders and partners, and our remarkable volunteers, it is inconceivable that we could continue on this extraordinary path. Thankfully, we have every reason to believe that 2018 will be another year of innovation, growth, and service as we continue to strive to meet the needs of our residents and our animals in a proactive and progressive manner.
Robert A. Marotto is Orange County's Animal Services director and currently chairs the N.C. Animal Federation.


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Apr 24, 2010
LYNCHBURG, Va. – The Washington and Lee baseball team had its 2010 season end on Sunday morning with an 8-3 loss to fifth-seeded Lynchburg in an ODAC Tournament game that took two days to complete at City Stadium.
The No. 6 Generals were trailing the No. 5 Lynchburg Hornets, 7-1, when play was suspended due to rain before the Generals came to bat in the seventh inning. The game was resumed at 11:00 am on Sunday morning in the top of the seventh inning.
Lynchburg (23-14-1) took a 1-0 lead in the first inning on an RBI double by Brock Shiflett before W&L tied the score at 1-1 in the third inning when senior catcher Will Lewis (Columbia, S.C./A.C. Flora) singled home first-year shortstop Jonathan Stutts (Charlotte, N.C./Charlotte Country Day).
The Hornets responded with three runs in the bottom of the frame, including a two-run double by Shiflett to take a 4-1 lead. LC then added a single run in the fifth and a pair of runs in the sixth before play was suspended.
When play resumed, the Hornets scratched across a run in the bottom of the eighth inning on a sacrifice fly by second baseman Jordan Watkins to extend LC's advantage to 8-1.
After retiring the first six batters that he faced, LC's Josh Youngman ran into trouble in the ninth inning as W&L tallied a pair of runs on an RBI single by senior first baseman Hunter Serenbetz (Stamford, Conn./Taft School) and an RBI double by senior third baseman Jim Plantholt (Pylesville, Md./North Harford) to pull W&L within five runs at 8-3.
However, Jared Milner relieved Youngman with two outs in the ninth and got sophomore designated hitter Alston James (Columbia, S.C./Hammond) to fly out to left to end the game.
Senior Chuck Davidson (Winnetka, Ill./New Trier) started on one days rest for W&L and took the loss (4-6) as he allowed five runs on nine hits and one walk with four strikeouts in 4.0 innings of work. He did pitch to two batters to lead off the fifth inning.
Matt Morgan earned the win (4-0) for Lynchburg as he surrendered just one run on six hits and three walks with a pair of strikeouts in 6.0 innings.
Plantholt finished 3-for-5 with an RBI to lead the Generals at the plate. Lewis finished 2-for-4 with a walk and an RBI. Stutts was 2-for-3 with a walk and a run scored and senior second baseman John Ditore (Seattle, Wash./Bishop Blanchet) and sophomore centerfielder Mike Decembrino (Yardley, Pa./Pennsbury) both singled and scored a run.
Lynchburg's top five hitters went a combined 11-for-19 with eight runs and seven RBIs to pace the Hornets. Leftfielder Mike Walters was 2-for-5 with two runs, centerfielder Cameron Grant was 2-for-5 with two runs scored and an RBI. Rightfielder Jeff Taylor had two hits in five at-bats with two walks, three runs scored, one RBI and a stolen base. Shiflett was a perfect 3-for-3 with two walks, four RBIs and a run scored and first baseman Chris Colquhoun was 2-for-3 with an RBI.
At the conclusion of play, Stutts and Plantholt were both named to the all-tournament team. Stutts hit .500 (6-12), with three walks, three runs scored and two stolen bases in W&L's four tournament games, while Plantholt was 6-for-16 (.375) with a double and three runs driven in.
The Generals conclude their season with an overall record of 14-19 and Lynchburg advances to the ODAC Championship where it will face Bridgewater at 1:00 pm.


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I stayed at the bar and helped clean up cause I was told I'd get free shots. Didn't happen.
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That's the oldest trick in the book!
Hate when that happens.
First. Merry Christmas.
Yeah, someone tricked me into doing this over the summer...and inevitably almost got my ass kicked.


text: Memory# Publisher: Hiskores Inc. Genre: Education Released: 23 Nov, 2009 Size: 1.3 MB Price: $0.99 Click here to request a review of this app App Store Info Description Help you to memorize 6 cards in 3 seconds. Improve your memory. Please practise for at least 3 days. What's New in Version 1.1 Some graphic changes Screenshots Screenshot 1 of 4


text: I'm looking for a few Facebook gurus that have many accounts/groups/fanpages. I'm launching a Facebook application and looking to make it grow. I will require users to send out invites via app, send chips to friends ( yes this is a poker application built in flash as3) suggest app fan page to friends or promote via your own fan page(s). Please pm me with what you are capable of providing and your price. I'm open to trading status updates on fan pages as I have an active and verified fan page which has 160,000 fans, which 90% of them are from the USA.


text: Bonniot and Farrand Launch Uncle Published on January 31, 2003. Former A Band Apart executive producer Eric Bonniot and director Jason Farrand, formerly of Atlas Pictures, have joined together to launch Uncle, Santa Monica's newest production company. In addition to Farrand, the company's roster includes former Atlas director Kerry Shaw Brown; agency veteran and former Big Leap director Rick Rabe; and Ash Beck, formerly of Squeak. Vamp Films' Dodonna Bicknell also joins the startup as executive producer. Most Popular In this article: Creativity News