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Dissertation Topic Selection & Outline
Are you looking for unique and innovative dissertation topic based on the strong research gap substantiated with the latest review? Do you want to assess the feasibility of uniqueness of dissertation topic being selected by you? Are you looking to conduct a brainstorming session with our expertise about topic selection?
Then You've Certainly Reached the Right placePlace an Order
We Select Topic for your UK & the US dissertation
The most demanding & daunting task of the dissertation writing is the research proposal. At Tutors India, we offer research proposal writing service, where you can relax and remain stress free given that work being handled by an experienced researcher.Our Process
Tutors India Difference in Topic Selection
For the majority of students, the UK / the US dissertation writing is a far most challenging piece of academic work that they have attempted or ever likely to try in the future. The majority of the students do agree and would have experienced the scenario. The significant concern that students struggle during this period is to identify the appropriate UK or the US dissertation topic that has well conceptualized and has a very clear set of aims. This is even more challenging for students from non-English speaking countries such as Brazil, Chinese, Malays, Singaporeans, Indonesia and other Asian countries.
Unique & Innovative Topic Selection based on the recent trends
Tutors India Dissertation topic/ title provide a convincing rationale for critical decisions. We select topics from three sources, from student, supervisor, and external organization
Student: As this would reflect some long-standing interest that they would have developed during the part of the course.
Guide/supervisor /mentor: Whom they would have built a relationship as part of an ongoing research project and their potential publications and,
Organization or Industry: An external organization where they are currently working (may be an industry problem).
Organization or Industry: An external organization where they are currently working (may be an industry problem).
Research papers: We help you to get ideas from research papers including database like PROQUEST, Science Direct, JSTOR, Emerald, Web of Science, IEEE, Google Scholar…
UK/ the US dissertation topic selection
Topic selection for master's dissertation is important as the experience gained at this stage would provide enormous benefits (e.g., obtaining a job, work experience, gain analytical skills, and improve research skills).
We Select Topic for your UK or the US dissertation
At Tutors India, we offer a topic that is well-grounded in the scholarly literature, manageable with given time frame, resources, availability of data sources, within your range of competence. Significant in practical or theoretical terms? Original & not been done before & ensure that the topic takes you where you want to go.
What Services do we offer under dissertation topic selection?
|3-4 topics along with the research aim.
|One standard topic selection and 500 words outline with research aim, objectives, literature review, research methodology, data analysis guidelines and references lists (upgradable)
|one standard topic with 1000 words along with advanced features and expected contribution, research gap, and bibliography for additional reading (upgradable)
|Type of editing
|Premium Editing
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|Standard Proofread
|Typographical errors
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|Terminology/reference check
|Logic, relevance and clarity
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|Cover letter
|Tutors India certificate
|On request
Specialized Subject Matter Expertise across the globe
We offer topic Selection for Management, Social Science, Engineering, Technology, Life Science, Medical, Arts & Literature / Linguistics, and much moreOur Writers
All your Topics are chosen by qualified and experienced researchers from the US & UK
Our writers have robust experience in research methodology, industry (domain specific), and educational degrees from international and top-ranked universities from India, the US, and the UK.Our Writers
Topic Selection Service Features
Based on Research Gap
The dissertation topics are selected based on the research gap and future recommendations proposed by previous researchers. Our topic selection is driven by your research question that is interested in exploring. We adjust and iterate the topic based on the research question and as we start finding the new resources. Tutors India ensures that topic is not too narrow or broad.
Detailed Literature Review & Industry Problem
The Aim and research objectives proposed which would be developed based on the detailed literature review and industry problem. We use a wide range of information to discover the topic including statistics, news reports, textbooks, historical information and of course recent peer-reviewed scholarly articles from the peer-reviewed journals.
Proposed Methodology & Expected Outcome
A literature review would be key in your dissertation therefore we provide recent articles published in the proposed area and gaps identified and proposed a methodology which would also cover research design, qualitative or quantitative, target population, data collection methods, tools used and finally expected outcome.
Topic Speaks about Your Research
To support our argument, we offer detailed references lists and bibliography.
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Free: Order a dissertation proposal, you will get free dissertation topic & outline – Use Promo code: TOPICPROP
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We deliver more than your expectation – ensure to provider the proper context, delimit the boundary condition, cite landmark studies, stay focused on the research question, a clear sense of direction, clear citation, APA or any other specific style.
Our topic selection service is exclusive
as we do not just provide topics, but the rather clear explanation and justification for the choice
Your Topic Selection
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Fully Referenced
Our dissertation work is fully referenced with latest articles and textbooks. We refer only peer-reviewed sources such as scholarly articles and textbook to select the topic. We refer database including Web of Science, ProQuest, Google Scholar, Business Source Complete, and latest newspapers articles such as Economic Times, Forbes, The Wall Street, The Economics to identify the industrial problem.
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(1) Unlimited Revision for the work being committed. (2) We ensure on-time delivery (3) We support 24/7. (4) Our word count committed does not include references and bibliography & help you to locate the sources cited (5) Ensure three-level quality check including Technical QC, Editor QC and final check against the requirement (6) Confidentiality of the information (7) Plagiarism free work – less than 5% percent. (8) Only experienced and subject specific writers will be allotted.
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We are aware of the consequences of plagiarism. Hence, topic selection is completely plagiarism Free. Our work is scanned against online sources in a similar way like WriteCheck or Turnitin. We wanted to ensure that our clients i.e., researchers and students are not finding any issues with regards to plagiarism and so we issue plagiarism-free certificate*. Our streamlined and high-quality research writing process ensures your dissertation is not just copy-pasted, but written only after brainstorming sessions with our team of professional researchers.
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Our work is delivered at a specified date and time. Our specific changes to the delivered work will be carried out within 45 days of delivery. We guarantee delivery of minor changes within 24 working hours and significant changes within 48 working hours. We acknowledge all your emails within 30 minutes of working hours. Further any delay in the delivery can be raised at email@example.com
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Our writers have experience in research methodology, industry experience, and educational degrees from international and top-ranked universities from India, the US, and the UK. We identify the perfect SME according to your subject and area. Expert is selected through a stringent selection process including the signing of non-disclosure and confidentiality agreement. You can be very sure about the quality of the work since expert writer is identified as per International Research Experience
Frequently Asked QuestionsView More
On which areas you provide dissertation topics and outline
At Tutors India, we provide dissertation topics in wide areas of research such as employee engagement dissertations, customer buying behaviour dissertation, project management dissertation, knowledge management dissertation, International marketing, performance management, strategic management and business policy, management of technology, international business, total quality management, public relation theories dissertation and many more. We also offer topics for various subjects such as MBA in HR, HRM, Finance, Economics, Operations, Nursing, medical, geographic, accounting, history, sociology, English, Music, advertising, fashion, tourism, architecture, computer science, politics, art, statistics
What Information that I need to provide while ordering for dissertation topic and outline
To provide topic and match exactly with your requirement, provide key research interested areas within your scope, target country, industry experience and feasibility of data collection, if any. And any other information that our writer should know also can be provided from your end.
How I can use my dissertation outline and topics?
The topics we provide would provide you clear and precise understanding of the proposed research area and ensure that you move in the right direction. A dissertation topic can be used
What if I require some customization in the topics we deliver?
Our service is completely flexible and tailor made to the customer. Hence, if you can provide the areas of customization related to research area initially proposed, we can make amendments in the dissertation topics.
What if my guide/professor rejects the topic and outline?
The service we provide is completely flexible. Hence, we can tailor made or customize your delivered topics based on the research area provided initially. Simply provide your modifications and we will deliver you according to the requirement.
Is there any option that I can use my dissertation topic and outline as a proposal?
The outline and dissertation topics that we provide is only a starting valuable guidelines enable to kick start your dissertation writing. The requirement was topic selection and outline and therefore it can only serve as guidelines for writing your proposal. Further, dissertation research proposal would have different set of guidelines and instructions specific to the university, and hence you should not be confused or expect research proposal with this requirement. However, we are happy to provide a custom proposal for your dissertation. To order a custom research proposal, you need to fill simple online order form along with the university guidelines.
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Tutors India has capability and skills to handle subjects across the field. We chose qualified and experienced subject specific expertise while you order your Ph.D. or Master's dissertation. We have more than 2000+ expertise working across the world who can handle arts, literature, sciences, engineering or medicine.
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The following image shows the shipbreaking yards at Alang, an industrial complex north of Mumbai in the Gulf of Khambhat. Photo taken from space via Digital Globe.
A huge portion of the world's merchant fleet finds itself beached at the end of its useful life at Alang, a workplace that also claims the lives of many of its workers as well. The following documentary gives a fascinating account of the business of shipbreaking.
In an editorial last year, Jacob Sterling, Head of Environment & Corporate Social Responsibility at Maersk Line makes the call for more responsible and environmentally-friendly ship recycling processes. "When ships are scrapped on beaches, I will argue that it is less likely that the materials are recycled to their full potential," comments Sterling. "Taking ships to proper recycling yards like the ones in China will enable a far better recycling of the steel for use in building new ships and other constructions."
Read more HERE.

subset: commoncrawl


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Trusted Choice agencies are insurance and financial services firms whose access to multiple providers and commitment to quality service enable us to offer our clients competitive pricing, a broad choice of products, and unparalleled advocacy. As a Trusted Choice agency, we are dedicated to you and are committed to treating you as a person, not a policy. This commitment means we shall:
- Work with you to identify the insurance and financial services that are right for you, your family, or your business, and use our access to multiple providers to deliver those products.
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- Help solve problems related to your coverage or account.
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EUR/JPY – Sell off continues, eyes 125.00 handle
JPY bulls are in no mood to relax amid fresh oil-driven risk-off in the equities and are now eyeing psychological level of 125.00 in the EUR/JPY cross.
Three-day losing streak
Taking into account a 150-pip fall seen today, the cross has been on a three-day losing streak. JPY bulls are making their presence felt, trapping analysts who had called for a fresh wave of JPY driven carry trades last week, on the wrong side of the trade.
It was widely believed that Yen funded carry trades would resume as new fiscal year starts in Japan. However, the move has caught many by surprise and is partly due to risk aversion in the markets.
Ahead in the day, focus is on the US ISM non-manufacturing data and sentiment in the US stock markets.
EUR/JPY Technical Levels
Spot may challenge bids around psychological figure of 125.00. If it cuts through the same, pair may test 124.67 (Mar 22 low), which is followed by a major support at 124.00 levels. On the other hand, a break above 125.38 (Mar 24 low) would shift risk in favor of a re-test of 126.09 (Apr 14, 2015 low) and 126.84 (daily high).
(Market News Provided by FXstreet)


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Through our insurance company, we purchased an Activa AdvantaJet from HealthMor Personel Care for our 11 year old son Amos Stowers. Amos was beginning to develop knots on his arms and buttocks from the insulin injections, even though he rotates his injection sites. We decided to check into the jet injectors as we had heard that using one did not cause the knots. I surfed the web to do my research. The Children with Diabetes pages were very helpful in my research. I compared the jet injectors listed on the products pages and called for additional information. The reasons we chose the AdvantaJet are:
- It allows 1/2 unit delivery of the insulin.
- It has 12 comfort settings.
- It has a 30 day money back guarantee, for any reason.
- A registered nurse, in our case a diabetes educator, comes to your home and teaches you how to properly use and clean the device. The nurse even gave me her home phone so I could call her if I needed any help at all. She spent 2 hours at our home, going over the usage and cleaning several times with Amos, not mom and dad, to be sure he could do it himself.
- A video with all the instructions the nurse gives you comes with it in case you forget something.
- 24 hour a day technical support.
- They helped us get the paperwork through our insurance company.
- If our insurance would not have covered it, they were willing to finance it for us at payments we could easily afford to make. The price was US$789.
- Amos was at the age where he bordered between the GentleJet and AdvantaJet. They sent us the AdvantaJet and told me that if it was too powerful for his skin type they would trade it for a GentleJet and refund the difference to our insurance company.
It took from July until September 1996 to get approval. HealthMor Personal Care sent our endocrinologist the forms necessary to get approval from the insurance company, had the doctor's office fax the completed forms back to them and they dealt directly with the insurance company on the matter. Every time I called HealthMor to check on the status, they would follow up and call me back and let me know how things were progressing.
When the nurse received the jet injector she called and set up an appointment to come to our house. She did an excellent job of demonstrating the injector. It comes with a bottle of saline solution for you to use to practice with, so that you can determine the comfort setting best for you. We injected everybody in our family so that we could all see and feel exactly how it works. I was shocked, it does not hurt at all, done properly.
I purposely gave myself a shallow injection as well as a deep injection, so that I would know what my son would experience if he should ever have a shallow or deep injection. The shallow one stung and it felt like the saline splattered out around the injection site. The deep injection hurt, comparable to bruising your arm and I did in fact get a hideous looking bruise that lasted about a week from it.
We started Amos out on the lowest comfort setting and by luck it was just the right one for him. Amos thinks everybody that is diabetic should have one. He does not understand that they do not work for everybody. We did discover that the injection site needs to have some fatty tissue to inject into. Amos has no fat at all on his stomach or on his thighs and even on the lowest setting he experiences a "shallow" type injection. However, he does have just a little bit of fatty tissue on his arms and his buttocks, so he rotates those sites.
We have demonstrated this device for our doctors, friends who are diabetic and others who are interested. Everyone is just amazed! We are completely satisfied with the product. We are also very satisfied with the follow up by HealthMor Personal Care. They call periodically to check to see if we are having any problems, if we need insulin vial adaptors, etc. When we did have a problem, we received an immediate answer and it worked. They called once a week for the first month, once every 2 weeks the next two months and once a month ever since.
We recently took a trip to Washington, D.C. I was concerned, "Would the air pressure at 40,000 ft have an effect on the injector? What about airport security, would they think it was a bomb? What should we do about taking it thru security? etc". I posted my concerns on the Parents of Children With Diabetes message board. I received two very helpful e-mail responses from members. I was assured that the air pressure was not an issue by a man who had been using an injector for a couple of years. In fact, he insisted that using the injector was much easier than using a syringe during turbulence. He was absolutely correct. We did have to use it during some terrible turbulence and I was glad we had it, a bump of turbulence could have cause a syringe needle to break off in his arm. I received another e-mail advising me to get a document from our endocrinologist stating Amos was diabetic and needed to carry insulin, a jet insulin injector, lancets, alcohol swabs and his glucometer with him. I did. I did not have to produce that document even once. We went through airport-type security in several of the buildings we toured. I just pulled the injector out of the fanny pack we carried our diabetic stuff in and explained what it was and had no problems at all.
Amos's insulin requirements dropped about 1/2 unit (Humalog) per injection. The absorption rate is much higher than with a syringe type injection. wW had to make an adjustment to the comfort setting last month because he has grown and his skin is getting a tiny bit tougher.
We realize that this product, like any other product, will not work for everyone, but it sure has worked well for us. If you would like more information you can e-mail me at firstname.lastname@example.com.
The opinions expressed in this article are those of the author and not necessarily those of children with DIABETES.
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Last Updated: Thursday February 27, 2014 19:28:20
This Internet site provides information of a general nature and is designed for educational purposes only. If you have any concerns about your own health or the health of your child, you should always consult with a physician or other health care professional.
This site is published by T-1 Today, Inc. (d/b/a Children with Diabetes), a 501c3 not-for-profit organization, which is responsible for its contents. Our mission is to provide education and support to families living with type 1 diabetes.
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AUGUSTA, Maine (AP) — A Maine legislative committee has unanimously endorsed a bill to authorize Gold Star Family license plates in Maine.
The Transportation Committee's action Thursday sets the bill up for likely legislative approval.
Secretary of State Charles Summers Jr. hailed the committee's action. He says the plate will be a solemn, dignified tribute to those who have given their life in service to their country.
The bill is sponsored by Republican Rep. Bradley Moulton of York.
Gold Star Family registration plates are expected to be made available by the end of the summer to families who qualify.


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Comment: Looking out for each other
THE recent spate of missing persons cases in this region underline the importance of people looking out for each other.
It is something we do quite well in this country, and we should never lose sight of it.
The large groups of volunteers engaged in these searches is symptomatic of this.
On a wider scale as winter takes its grip, the importance of care for the elderly is also extremely important.
The range of services that once existed for vulnerable groups is, in many cases, no longer there, or has been whittled down to be almost ineffective.
The need for good neighbours and strong community ethos has never been more acute.
Meanwhile, for the families of missing people, it is an inordinately difficult time and our thoughts are with them.


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Recently I was introduced to Lickibrush, a rubber brush shaped like a large tongue that is used by cat owners to bond with their pet. Picture this – the cat owner grips the Lickibrush in his teeth and combs it through the cat's fur with long grooming licking strokes. Most cats do this for themselves, but somewhere along the way some smart and crafty cat decided it would be easier to train their human to lick for them. As a result, the enterprising cat marketed Lickibrush as a tool for humans to bond with Frisky (or whatever their cat's name might be). Think about it; who is smarter – the cat getting a massage and groom without lifting a paw, or the silly human with a rubber tongue protruding from his face?
I like cats, and over the years, I bonded with several, but not once did it occur to me to strengthen that bond by licking them. Whether it is a cat or a human, there are consequences for cat licking. HAIRBALLS! A cat choking, gagging, and throwing up hairballs is a disgusting sight to behold and even worse to clean up. So, why in the name of all that is sane, would a cat owner want to engage in a process that will ultimately lead to convulsive heaving and expulsion of nasty human size hairballs? Who wants to clean up that mess? Bonding with my cat or any animal is just not that important to me!
I hope animal loving fanatics will forgive me, but I must politely and emphatically say, "NO!" to Lickibrush. The product simply does not make sense. However, I have several products I am preparing to market that not only make sense but are practical and beneficial in the world of animal lovers. Like Lickibrush, these products may appear to be a bit peculiar, but I can assure you unlike Lickibrush each one makes perfect sense and lends itself to practical application in the world of pet mania.
Five New Pet Products Every Pet Owner has to Have
This device is the ultimate gadget for getting into you dog's head. Dog owners wear the rubber dog snout with a soft pliable wet nose (simply moisten with water before each use) over their nose. When wearing the PooShootSniffer, dog owners can bond with Rover in ways never imaginable. The instructions are extremely simple – while wearing PooShootSniffer, the owner drops to his hands and knees behind their pet and sniffs. That is all there is to it! By sniffing Rover's butt, the owner says "I care," "I am here for you," and "You are special." PooShootSniffer is the perfect remedy for dogs that are depressed or lonely. WARNING: If your dog growls when you are using PooShootSniffer, back off! Rover is letting you know that he is uncomfortable, and you are violating his personal space.
This device is designed expressly for pet owners with talking parrots. However, it could just as easily be used with children to prepare them for watching movies, riding the school bus, or hanging out at the mall. Babelshit is an electronic device that is mounted on the side of Polly's cage. When switched on, it produces profanity in up to 64 languages. It audibly feeds Polly a steady stream of intoxicating four letter words. With Babelshit, your pet parrot as well as your kids can learn to curse like all the cool folks do these days. Now, how cool and classy is that?
Have you ever been away from home on business or a vacation and missed your pets? That can be a real bummer, and make the trip almost unbearable. However, Crapsteppers can help remedy that lonely displaced feeling. Crapsteppers are rubber shoe soles that smell like dog crap. Although it is sometimes impossible to bring your dog with you when out of town, with Crapsteppers, you can always bring the pungent smell of dog crap with you regardless of how far from home you travel. Simply slip Crapsteppers rubber soles on your shoes, and instantly it smells as though you have been wallowing in dog poo. The scented rubber soles can be worn on any shoe – casual or formal. Imagine yourself sitting in your next boring business meeting wearing a pair of Crapsteppers. While those around you are gagging, you can relax and almost feel Rover between your toes.
For those dog owners with limited room to pack, Crapsteppers also comes in a convenient travel size spray as well as sensible towelette packets. The great news is the rubber slip ons, the travel spray, and towelettes come in three nose titillating fragrances: Outdoorsy – a classic mixture of doggy poo and fresh cut grass; OopsyFresh – the warm fragrance of fresh doggy poo in an enclosed area (such as a living room or kitchen) mixed with elegant touches of morning bacon and coffee; and LingeringHeaven – the faint yet distinctive fragrance of well cured and forgotten or lost doggy poo.
Can't bring your best friend with you? Take along Crapsteppers! With Crapsteppers, you will never escape the lingering overpowering spice of dog poo that pet owners know and love so well.
This unique device is for the pet owner who is too busy or too lazy to take his dog for a walk, or the pet owner lives in an apartment with no space for Rover to run and play. The 3D device straps around Rover's head over his eyes, so he can have the sensation of going on long walks or running free in vast open fields of daises (watch where you step!). It is also ideal for overweight couch potato dogs. The truly smart dog owner will buy two DoggySEE/DoggyRUN devices, so he can share long leisurely walks in the park and runs through mountain meadows with Rover. For the thoughtful dog owner, DoggySEE/DoggyRUN is all about taking an active interest in the life of your pet.
The HumanDoggyDoor comes directly from the why didn't I think about this department! This ingenious structure is attached to and around a doggy door. It expands the opening so humans can also enter and leave the house or apartment at will. It comes complete with frame, door panels, and hardware to attach to Rover's door, and it has doorknobs the human can be trained to turn to enter or leave the house or apartment. The structure also comes with locks as part of the doorknob assembly, so Rover can lock his owner in or out of the house/apartment at his discretion.
There is nothing fancy about any of these products. They are products that are long overdue on the pet market. Therefore, the next time you are in the car, house, or movie theater and smell dog poo, don't ask who stepped in the poo, look for someone wearing rubber Crapsteppers instead.
©Jack Linton, May 2, 2017


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How to Make Henna or Mehndi Cone at Home
How to Hold Henna or Mehndi Cone
This post is created using experience and technique that Beena From ArtPassion shared in her below YouTube video. If you prefer watching the video instead of text then check her mehndi cone tutorial video.
Many people requested that I should teach them or show them the right way to hold henna or mehndi cone. It is very important to hold the henna cone in comfortable position while making Mehandi Design.
It is likely to teach the "Right Way" of holding a pen or pencil. There is no perfect way to show you how to hold a pen or pencil. Everyone holds the way they feel comfortable with, the way they have learned from the very beginning and the way their teacher taught them how to hold a pen pencil. Exactly same way holding mehandi cone is also depend on your own comfort way and everyone has their own difference style to hold it.
So I really sorry i can't teach the "Right Way" to hold henna or mehndi cone. But i can show you the way i hold my henna cone. I am not sure if it is right way or wrong way but that's the way I hold my henna cone. The most common way of holding mehndi cone is like this :-
- Keep mehndi cone in between your first and middle finger.
- Where henna cone is resting on the middle finger and the first finger is securing it. Both fingers concentrate on the motion of mehndi cone.
- And your thumb is getting more from grip while controlling pressure on the henna cone.
- Height: I hold henna cone from the height where I can rest my wrist on surface and control the cone and most of the time that's the top of my cone as i use smalls size cone. I need height so i can cover more area without stopping at points while drawing long lines or big motives. If I hold mehndi cone from near the teap then my movements get are limited and it could give me shaky lines.
- Angle: I like to hold my cone in around 85 90 degree angle.
- Size of cone: Now i would like to give one suggestion from my personal experience that if possible use small size mehndi cone. it's easy to control by your thumb and your fingers. After working for long hours with small size mehandi cone your hands and thumb won't get tired.
Where to get Mehndi Cone or Mehndi Paste ?
I always suggest to make your own henna cone with good quality henna. Not only it gives you best consistency but you also have a freedom to select consistency based upon size of cone.
There is no doubt that best quality henna paste gives best results to draw mehndi design images. It's good to use your own henna paste. Because always remember that in many latest henna designs we don't drag the lines. Check design in below simple mehnadi design image which I made without dragging lines. It can only be possible if you're mehndi paste is fresh.
Store-bought henna cones lack this quality. If for any reason you have to use the ready-made cone, go for better quality and transfer paste into your own empty cone. Now this is my suggestions, You should try the cones available near to you and experience the difference. Don't forget to let me know in below comment box. Until unless you test it you won't understand the difference.
How to Handle Partially filled Henna Cone
When henna cone is full it's easy to handle but the moment it started to be empty. its get complicated and little bit difficult to handle. What I do in such situations, I keep using till my thumb can handle the situation and when it become impossible to band the cone, I refill it. So now instead of pressing the cone I have to squeeze the cone. Check the image below how I squeeze the cone after refilling it. Once you learn it and start using, it will make your life easier.
Note: Be a little bit careful as squeezing too much can give messy design so little it easy
So, Till the squeezing cone works for me, I keep using my cone that way but when I feel now it's also getting difficult i use clip. This is the best technique I have learnt in past. What I do I just secure my cone with clip as shown in pic below with tightness I want with my cone. So i have my mehndi cone always like full cone. No need to use more pressure or do anything else and I can use my cone to the last bit of mehndi inside
Using another hand as a surface area
Many times while applying mehndi we don't have a surface to rest of our wrist. In that case, I use my other hand as a rest area and I keep it under my main hand. Sometimes we need to keep other hand in breeze type form so design below the other hand don't get ruined. But I always prefer to keep my hand on surface to get stability. Check the Image below
How to Clean the Henna or Mehndi Cone
I hold tissue paper or towel to clean the tip of the cone. I do it constantly because it's my habit now.
Check More Tips and Tricks and Designs for Mehandi Design


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Airtime 2000 wrote:Good lord, not ANOTHER Tornado! Thats 5 Tornado's opening this year at SF parks alone (SFSTL, SFDL, SFAW, SFKK and now this one). Plus Michigans Adventure is getting one. At this rate, every SF park will have a Tornado by 2008.
Return to Theme Parks, Roller Coasters, & Donkeys!
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text:
We've gone out of our way to highlight this series because we want to make sure that all of our customers are aware of it and so have the opportunity to take advantage of this tremendous value.
Produced on a semi-regular schedule in London, England, each of the Proper Records Box Sets contains four CDs and a booklet of 40 to 68 pages in length. Each CD is packed to its limit, so every set holds close to five hours of music -- which in most cases translates to around 100 individual tracks. And what music! High quality mastering accompanies an extremely discerning selection of the finest recordings of popular music of the first half of the 20th Century. While the focus is on Jazz -- and let's face it: that's where the majority of the best music was being made (or at least recorded) during the period 1900 -1955 -- there is nevertheless quite a variety to choose from: the great male and female vocalists, swing, blues, bluegrass, country & western, celtic, ska, gospel and more; with new additions coming every few months or so. And everything is good, especially the price. Through the combination of employing several different sources and increasing our volume, we are currently able to offer each set for the copacetic price of only $29.75 per box!
SPECIAL NOTE: You may now purchase Proper Boxes 1 through 134 directly over the web (payments through PayPal) from The Proper Box Zone at Copacetic 2.0., our new 24/7 eCommerce site. We'll add the more recent Boxes as soon as we can.
Here's an alphabetical list of all the boxes currently available for sale (parenthetical comments are ours):
PROPERBOX70 Roy Acuff King of Country Music
PROPERBOX157 Cannonball Adderly 'Dis Here' ¡NEW!
PROPERBOX24 Louis Armstrong Satchmo in the Forties (THIS IS IT!)
PROPERBOX93 Louis Armstrong King Louis (ABSOLUTELY NECESSARY)
PROPERBOX67 Eddy Arnold Eddy's Song
PROPERBOX57 Mildred Baily Mrs. Swing
PROPERBOX84 Chet Baker The Early Years
PROPERBOX19 Count Basie The Count Basie Story
PROPERBOX18 Sidney Bechet The Sidney Bechet Story (HOT!)
PROPERBOX66 Bix Beiderbecke The Bix Beiderbecke Story
PROPERBOX121 Tony Bennett Young Tony
PROPERBOX132 Art Blakey The Prime Source
PROPERBOX112 Earl Bostic The Earl Bostic Story
PROPERBOX86 Clifford Brown Joy Spring
PROPERBOX59 Milton Brown Daddy of Western Swing
PROPERBOX90 Dave Brubeck Time Was
PROPERBOX141 Cab Calloway & His Orchestra This Is Hep
PROPERBOX127 The Carter Family Country Folk
PROPERBOX68 Benny Carter The Music Master
PROPERBOX158 Serge Chaloff Boss Baritone ¡NEW!
PROPERBOX133 Ray Charles The Way I Feel
PROPERBOX98 Charlie Christian The Original Guitar Genius
PROPERBOX161 Sonny Clark Sonny's Conception ¡NEW!
PROPERBOX120 Kenny Clarke Klook's the Man
PROPERBOX31 Nat King Cole Cool Cole, The King Cole Trio Story (MAX SUAVE)
PROPERBOX34 Bing Crosby It's Easy To Remember
PROPERBOX17 Miles Davis Young Miles
PROPERBOX105 Doris Day Sentimental Journey
PROPERBOX138 Fats Domino The King of New Oreleans Rock 'n' Roll
PROPERBOX69 Roy Eldridge Little Jazz Trumpet Giant
PROPERBOX25 Duke Ellington Masterpieces, 1926-1949 (AWE INSPIRING)
PROPERBOX74 Ella Fitzgerald Romance and Rhythm
PROPERBOX116 Ella Fitzgerald Dearly Beloved
PROPERBOX107 Red Foley Hillbilly Fever
PROPERBOX119 Lefty Frizzell Give Me More, More, More
PROPERBOX62 Slim Gaillard Laughing In Rhythm (VOUT OREENEE!)
PROPERBOX52 Stan Getz The Sound
PROPERBOX30 Dizzy Gillespie The Dizzy Gillespie Story 1939-1950 (TOP BOP)
PROPERBOX109 Benny Goodman The Essential BG
PROPERBOX16 Dexter Gordon Settin' The Pace
PROPERBOX55 Wardell Gray The Wardell Gray Story
PROPERBOX115 Woodie Guthrie Some Folk
PROPERBOX118 Bill Haley From Western Swing to Rock
PROPERBOX160 Joe Harriott The Joe Harriot Story ¡NEW!
PROPERBOX117 Tubby Hayes The Little Giant
PROPERBOX12 Lionel Hampton The Lionel Hampton Story (JUMPIN')
PROPERBOX20 Wynonie Harris Rockin' The Blues
PROPERBOX14 Coleman Hawkins The BeBop Years
PROPERBOX15 Woody Herman The Woody Herman Story
PROPERBOX58 Johnny Hodges The Jeep is Jumpin'
PROPERBOX26 Billie Holiday The Lady Sings (A REASON TO LIVE)
PROPERBOX111 John Lee Hooker The Boogie Man
PROPERBOX63 The Hoosier Hot Shots Everybody Stomp
PROPERBOX123 Lightin' Hopkins Texas Thunderbolt
PROPERBOX154 Howlin' Wolf The Best of (3 CD + DVD)
PROPERBOX106 Mahalia Jackson Come to Jesus
PROPERBOX126 Milt Jackson Bags of Soul
PROPERBOX49 Illinois Jaquet The Illinois Jaquet Story
PROPERBOX81 Lonnie Johnson The Original Guitar Wizard
PROPERBOX5 Spike Jones and his City Slickers Strictly for Music Lovers
PROPERBOX47 Louis Jordan Jivin' with Jordan
PROPERBOX13 Stan Kenton The Stan Kenton Story
PROPERBOX1 Gene Krupa The Gene Krupa Story (THE MAN!)
PROPERBOX148 Leadbelly The Definitive
PROPERBOX45 Peggy Lee The Peggy Lee Story
PROPERBOX108 Peggy Lee Miss Wonderful
PROPERBOX125 Jimmy Lunceford Strictly Lunceford
PROPERBOX48 Machito and His Afro-Cubanos Ritmo Caliente
PROPERBOX104 Dean Martin Young Dino
PROPERBOX23 Glenn Miller The Golden Years, 1938-1942
PROPERBOX77 Charlie Mingus The Young Rebel
PROPERBOX101 Thelonious Monk Monk's Moods
PROPERBOX113 Jelly Roll Morton Doctor Jazz
PROPERBOX96 Gerry Mulligan Jeru
PROPERBOX11 Fats Navarro The Fats Navarro Story
PROPERBOX21 Anita O'Day Young Anita (SASSY)
PROPERBOX46 Charlie Parker Boss Bird (KLACTOVEESEDSTENE!)
PROPERBOX99 Charlie Parker Chasin' the Bird
PROPERBOX151 Charlie Patton The Definitive (3 CD + DVD)
PROPERBOX134 Les Paul & Mary Ford In Perfect Harmony
PROPERBOX94 Oscar Peterson Piano Power
PROPERBOX35 Edith Piaf Love and Passion
PROPERBOX153 Charlie Poole The Essential
PROPERBOX22 Bud Powell Tempus Fugue-It (CLASSY)
PROPERBOX137 Elvis Presley The Tupelo Mississippi Flash
PROPERBOX156 Louis Prima Buono Sera ¡NEW!
PROPERBOX53 Django Reinhardt Swing de Paris
PROPERBOX92 Shorty Rogers West Coast Jazz
PROPERBOX124 Sonny Rollins Sax Symbol
PROPERBOX131 Ronnie Scott Boppin' with Scott
PROPERBOX159 Phil Seamen Seamen's Mission ¡NEW!
PROPERBOX85 Artie Shaw The Artie Shaw Story
PROPERBOX40 George Shearing From Battersea to Broadway
PROPERBOX33 Frank Sinatra All Or Nothing At All
PROPERBOX78 Bessie Smith Chattanooga Gal
PROPERBOX139 Jimmy Smith Electrifyin'
PROPERBOX87 Sons of the Pioneers My Saddle Pals and I
PROPERBOX36 Jo Stafford Yes Indeed!
PROPERBOX65 Sonny Stitt Sax O' Bop
PROPERBOX130 Maxine Sullivan It's Wonderful
PROPERBOX60 Art Tatum Piano Grand Master
PROPERBOX80 Jack Teagarden Big "T"
PROPERBOX51 Sister Rosetta Tharpe The Original Soul Sister
PROPERBOX73 Mel Torme Jazz and Velvet
PROPERBOX64 Lennie Tristano Intuition
PROPERBOX54 Ernest Tubb The Texas Troubadour
PROPERBOX89 Big Joe Turner Shout, Rattle and Roll
PROPERBOX155 Various Artists Larkin's Jazz ¡NEW!
PROPERBOX150 Various Artists Roots of Bob Dylan (3 CD + DVD)
PROPERBOX149 Various Artists Roots of Led Zeppelin (3 CD + DVD)
PROPERBOX147 Various Artists Little Red Book of Protest Songs (3 CD + DVD)
PROPERBOX146 Various Artists Rare Rock 'n' Roll Rampage
PROPERBOX145 Various Artists Little Walter and the Kings of the Blues Harmonica
PROPERBOX143 Various Artists Rockin' Memphis
PROPERBOX142 Various Artists Steelin' It: The Steel Guitar Story
PROPERBOX140 Various Artists With My Little Ukelele In My Hand
PROPERBOX135 Various Artists Rock 'n' Skiffle: Brit Beat Beginnings
PROPERBOX129 Vaious Artists The Cosimo Matassa Story
PROPERBOX128 Various Artists Gypsy Jazz
PROPERBOX122 Various Artists Classic Rockabilly
PROPERBOX114 Various Artists Squeeze Me - The Jazz & Swing Accordian Story
PROPERBOX110 Various Artists The Louisiana Hayride Story
PROPERBOX103 Various Artists From Boppin' Hillbilly to Red Hot Rockabilly
PROPERBOX100 Various Artists We're Gonna Rock, We're Gonna Roll
PROPERBOX95 Various Artists Blazing Bluegrass
PROPERBOX91 Various Artists Cajun Capers: Cajun Music 1928-1954
PROPERBOX88 Various Artists Jazz in Britain 1919 - 1950
PROPERBOX83 Various Artists Stompinn' Singers & Western Swingers
PROPERBOX82 Various Artists Jazz at the Philharmonic
PROPERBOX79 Various Artists Doo-Wop Delight
PROPERBOX76 Various Artists The Arranger's Touch
PROPERBOX75 Various Artists Swinging Hollywood Hillbilly Cowboys
PROPERBOX72 Various Artists Kings of Komedy
PROPERBOX61 Various Artists The Big Horn
PROPERBOX56 Various Artists Swing Tanzen Verboten: Swing & the Nazi Era
PROPERBOX50 Various Artists Hillbilly Boogie (TWANGIN')
PROPERBOX44 Various Artists The Dawn of Doo-Wop
PROPERBOX42 Various Artists Good News: 100 Gospel Greats (GET THE SPIRIT!)
PROPERBOX29 Various Artists Bluegrass Bonanza
PROPERBOX28 Various Artists Gettin' Funky - The Birth Of New Orleans R&B
PROPERBOX10 Various Artists Bebop Spoken Here (COOL, AS IN DEFINITIVE)
PROPERBOX9 Various Artists Hittin' On All Six
PROPERBOX7 Various Artists Broke, Black and Blue
PROPERBOX6 Various Artists Doughboys, Playboys and Cowboys
PROPERBOX4 Various Artists Deep Ska (DEEP)
PROPERBOX3 Various Artists Farewell to Ireland
PROPERBOX2 Various Artists The Engine Room (THE JAM!)
PROPERBOX27 Sarah Vaughan Young Sassy
PROPERBOX41 Charlie Ventura Bop for the People
PROPERBOX38 T-Bone Walker The Original Source
PROPERBOX71 "Fats" Waller Handful of Keys
PROPERBOX43 Dinah Washington The Queen Sings
PROPERBOX102 Muddy Waters King of Chicago Blues
PROPERBOX152 Muddy Waters Steppin' Stone (3 CD + DVD)
PROPERBOX97 Chick Webb Stomping at the Savoy
PROPERBOX37 Ben Webster Big Ben
PROPERBOX39 Hank Williams Hillbilly Hero
PROPERBOX32 Bob Wills and His Texas Playboys Take Me Back To Tulsa
PROPERBOX8 Lester Young The Lester Young Story
¡NEW! - The Proper Deluxe Box Set Series
As best we can tell, this series is simply a revival of the jewel-box format of the first 83 Proper Boxes. In every way they are identical to the rest of the Proper Boxes (4 discs; 5+ hours; 48 - 64 page booklet; etc). The boxes do display a seal, however, that states, "Limited Edition Deluxe Box Set." So, perhaps, these boxes have smaller print runs than the standard Proper Boxes, and will not be kept available, as the Proper Boxes (generally) are, but allowed to sell out. We'll let you know if/when we find out more. Here are the first of the "Deluxe" Boxes:
Proluxe 5001 Buddy Rich Strike It Rich
Proluxe 5002 Oscar Pettiford Oscar Rides Again
Proper Box Set Series:
copacetic price - $29.75
ordering info
SPECIAL NOTE: You may now purchase Proper Boxes 1 through 134 directly over the web (payments through PayPal) from The Proper Box Zone at Copacetic 2.0., our new 24/7 eCommerce site. We'll add the more recent Boxes as soon as we can.
A Note on Availability: Every effort is being made to keep the entire Proper Box Series available for immediate shipping at all times. However, from time to time temporary holes may appear in our stock. Should it occur that you request a particular box which we are out of stock of at that moment, we will contact you as soon as it is back in stock. Current stock status is listed below.
Actual Availability (we'll update this as often as possible) as of 30 November 2011:
All Proper Boxes are currently in stock except: 33, 38, 50, 56, 66, 71, 79, 81, 91, 98, 128 & 144
A SPECIAL UPDATE ON THE PROPER BOX SERIES FORMAT: Beginning with Proper Box 84, Proper Records adopted a new compact format for the Proper Box series. In addition, each time a particular box sells out of stock, it will be reissued in this format (as about half have been so far). This new format eschews the bulky, petro-chemical consuming jewel case and opts instead for an LP-style jacket to hold each of the four CDs (just so there's no confusion: there are four LP-style jackets -- one for each disc). The booklet design has not been affected, but it is 1/2" narrower than originally; however, the quality of paper stock has been improved and there has been, on average, an increased page count for the booklets, so rest assured that there is no skimping going on. What we have here is a new and improved format that will provide you with the same amount of music with the same high quality and with equal if not superior support materials, but will use less resources to manufacture and -- importantly, as these are made in England -- cost less to ship, enabling us to continue to offer these at the same amazingly low price. And, as an added bonus, they will take up less than half the space on your shelves at home!UPDATE ON THE PROPER BOX SERIES FORMAT #2A: Proper Box numbers 147 through 155 are slimmed down even further and – in most, but not all cases – contain 3 CDs and 1 DVD instead of simply 4 CDs as had all previous boxes. Begining with Proper Box 156, the format returns to the above format that it had beginning with Proper Box 84, with the notable exception that the booklets have – so far, since returning to this format with PB 156 – all been 20-24 pages each; leaner than previously.
• Proper Introduction
• Proper Pairs
• The Copacetic Library of Jazz Books
Copacetic Commodities


text:
by Saurabh Somani
A match that began with a celebration of Sachin Tendulkar, ended with a celebration by Sachin Tendulkar.
But like for much of his life, the celebration of him was loud, unending and rapturous while the celebration by him was animated, brief and not over the top.
Tendulkar had combined with Gautam Gambhir to keep Sri Lanka at bay and earn a draw for India, on a pitch that was a bad advertisement for Test cricket.
Both Tendulkar and Gambhir scored centuries - bringing the the total number of centuries in the match to seven - but their knocks were more about their mind conquering their impulses than their mind and skills conquering the bowlers and the conditions.
India began the day, trailing by 144 runs, and ended it leading by 78. In between, Sri Lanka picked up the wickets of nightwatchman Amit Mishra and centurion Gautam Gambhir.
Mishra and Gambhir had ended Day 4 well for India, with Mishra displaying decent batting talent. He continued the good work in the morning, while Gambhir looked like he had set himself up to bat throughout the day. Mishra had progressed to 24, when he flicked Angelo Mathews off his pads for a good-looking shot, only to see Dilshan come in between the ball and its intended course towards the boundary. It was a brilliant reflex catch, and was so unexpected that Mishra actually stood for a while in disbelief. However, this innings would have not only given him the confidence to bat in future Test matches, but it will also be a valuable, though subtle, confidence boost in the minds of the established batsmen who will now know that Mishra can be relied upon to hang around if they find themselves batting with him towards the end of an innings.
After Mishra's fall, Tendulkar walked out to the crease to join Gambhir. On a road of a pitch, Tendulkar and Gambhir eschewed any risks, but didn't pull down the shutters altogether and kept the scoreboard moving. They took India to lunch, still trailing Sri Lanka by 78 runs, but with no threat to losing their wickets if they kept their heads.
Gambhir had reached his seventh Test century in the first session, displaying an uncanny ability to lift his game when his team needed him the most. This was his 6th century in his past 8 Test matches, underlining the rich vein of form he has been in during the past year and more. This was also the fourth time Gambhir had made a century in his second innings during a Test match. In fact, Gambhir's average in the second innings of all Test matches he has played went up to an astounding 63.67. Taken in conjunction with a very good first innings average of 48.70, it tells you just why Gambhir has been so valuable for India at the top of the order.
However, after lunch, Gambhir momentarily lost his cool and had to pay for it with his wicket. He charged down the track to Rangana Herath and, much like his friend and opening partner Sehwag, ended up giving a dolly to mid-off. Gambhir had done his job though and played a large part in taking India to safety. After Gambhir departed for 114, the old warhorses - Laxman and Tendulkar - got together and their partnership was unbroken till the end of the match.
The final day's play had been in stark contrast to the frantic run-gathering of the previous four days, but at no stage did either Laxman or Tendulkar look discomfited. They took India's total past the deficit-mark of 334, and progressed serenely towards their respective individual landmarks - Laxman to his fortieth half-century and Tendulkar to his forty third century.
As Tendulkar reached the nineties, Sangakkara changed bowling tactics, with all the bowlers bowling negative lines. However, Tendulkar was equal to the task, once turning a ball from miles outside off-stump to the square-leg boundary, and once stroking the ball through a packed off-side cordon for another boundary. He reached his century with a scampered single off Welegedera, and had an animated but brief celebration.
The match was then called off at the end of the over, with Tendulkar unbeaten on 100 and Laxman on 51.
It is worth noting that but for the brief burst from Welegedera on the first morning, there was nothing in the pitch for the bowlers. The Indian cricket administrators have consistently maintained that they want to uphold the purity and sanctity of Test cricket, and they are not merely looking to cash in on the popularity of the limited-overs formats. However, with pitches like these, it is the surest way of killing interest in Test cricket.
This pitch would have been great for an ODI or a Twenty20 match with the likelihood of big scores from both sides. But for a Test match, that demands an equal battle between bat and ball to be compelling, it was a disaster. There were almost 1600 runs scored in this Test, and only 21 wickets were lost.
In the immediate future, Sri Lanka would be hoping for more sporting pitches to end their win-drought on Indian soil. In the extended future, every fan of Test cricket would be hoping for more sporting pitches so that the most challenging format of the game is alive and flourishes.
For the previous days match reports:
Match Report Day 1 - click here.
Match Report Day 2 - click here.
Match Report Day 3 - click here.
Match Report Day 4 - click here.
India salvage draw with Tendulkar, Gambhir tons
by Saurabh Somani


text:
|System: Wii
|Review Rating Legend
|Dev: Good Feel
|1.0 - 1.9 = Avoid
|4.0 - 4.4 = Great
|Pub: Nintendo
|2.0 - 2.4 = Poor
|4.5 - 4.9 = Must Buy
|Release: Sept. 22, 2008
|2.5 - 2.9 = Average
|5.0 = The Best
|Players: 1
|3.0 - 3.4 = Fair
|ESRB Rating: Everyone
|3.5 - 3.9 = Good
Finishing a level within a time limit plays out differently than one might expect, that is unless you have played previous Wario Land titles. Players will traverse levels, making their way to a metal prison that holds an innocent denizen of the Shake Dimension captive. Once found, players will need to shake it until its captives are set free. Unfortunately, as soon as it breaks, an alarm sounds, giving players a limited amount of time to make it back to the beginning of the level. If you fail to make it in time, you will be unable to keep the treasure and coins you've managed to collect during that level. Fortunately, there is really no reason to fear this, as it is often incredibly easy to beat these generous countdowns. The only real challenge lies in trying to beat the time set by the missions. Successfully completing missions and finding treasure is not necessary to advance in the game but it definitely adds to the game's replayability.
Boss battles have always been a major part of every Wario Land game to date and Shake It! is no exception. One of the best is a floating face that needs to be fed enemies and eventually bombs to be defeated. Another has Wario piloting a rocket propelled unicycle, complete with an extending arm fashioned to a boxing glove. Players will need to tilt the Wii-mote left and right to speed up and slow down, all while punching incoming debris back at the car of your enemy. This redirected trash knocks out the vehicle's engines, allowing Wario's boxing glove to pummel the car and eventually its occupant into oblivion. These battles are as challenging as ever and will often test players' reflexes and patience.
Aside from the unfortunate incorporation of shaking everything you come across, the only other flaws in Shake It! came from its visuals and sound. The sound effects were great but the music didn't quite strike the funky chord that many fans of the series have come to expect. Wario himself and the various characters you'll come across during the game look like well animated cartoons. However, the backgrounds and platforms in the game criminally lack detail. Often backgrounds appear like water-colored paintings, consisting of little more than empty space with very few objects present. Most of the game's levels are also fairly bland-looking, leaving one wondering exactly why the Wii's hardware wasn't put to better use with this title.
Even with its minor faults, Wario Land: Shake It! still manages to be a great platforming experience. Shaking your controller gets old very quickly, but the tried and true platforming goodness that is Wario Land, thankfully, remains intact. With all the hidden levels and treasures to be found and each level's missions to complete, Shake It! will also provide players with many hours of enjoyment, even after completing the game. Hopefully, this will be the first of many Wii Wario Land sequels to come.
Adam Brown
CCC Staff Contributor
Game Features:


text:
Medically reviewed on Sep 10, 2018
(peg VI soe mant)
Index Terms
Dosage Forms
Excipient information presented when available (limited, particularly for generics); consult specific product labeling.
Solution Reconstituted, Subcutaneous:
Somavert: 10 mg (1 ea); 15 mg (1 ea); 20 mg (1 ea); 25 mg (1 ea); 30 mg (1 ea)
Brand Names: U.S.
- Somavert
Pharmacologic Category
- Growth Hormone Receptor Antagonist
An analogue of human growth hormone, pegvisomant selectively binds to growth hormone (GH) receptors, blocking the binding of endogenous GH, leading to decreased serum concentrations of insulin-like growth factor-1 (IGF-I) and other GH-responsive proteins. Pegvisomant is made up of a recombinant DNA protein covalently bound to polyethylene glycol (PEG) polymers.
SubQ: 57%
Urine (<1%)
Time to Peak
Serum: 33 to 77 hours
Half-Life Elimination
~60 to 138 hours (~2.5 to 6 days)
Use: Labeled Indications
Acromegaly: Treatment of acromegaly in patients who have had an inadequate response to surgery or radiation therapy, or for whom these therapies are not appropriate.
There are no contraindications listed in the US manufacturer's labeling.
Canadian labeling: Hypersensitivity to pegvisomant and any component of the formulation.
Dosing: Adult
Acromegaly: SubQ: Initial loading dose: 40 mg; maintenance dose: 10 mg once daily following initial loading dose; doses may be adjusted by 5 mg increments or decrements in 4- to 6-week intervals based on IGF-I concentrations (maximum maintenance dose: 30 mg daily)
Dosing: Geriatric
Refer to adult dosing.
Dosing: Renal Impairment
There are no dosage adjustments provided in the manufacturer's labeling (has not been studied).
Dosing: Hepatic Impairment
At initiation of therapy:
Normal liver function test (LFT): Initiate therapy; monitor LFT monthly for first 6 months, quarterly for next 6 months, then biannually the following year.
Baseline LFT elevated but ≤3 x ULN: May initiate therapy with monthly evaluation of LFT for 1 year then biannually the following year.
Baseline LFT >3 times ULN: Do not initiate treatment without comprehensive work-up to determine cause; monitor closely if treatment is started.
With ongoing therapy:
LFT ≥3 x but <5 x ULN without signs/symptoms of hepatitis, hepatic injury, or increase in total bilirubin: Continue treatment, but monitor LFT weekly for further increases; perform comprehensive hepatic work-up to rule out alternative cause of hepatic dysfunction
LFT ≥5 x ULN or transaminase ≥3 x ULN associated with any increase in total bilirubin (with or without signs/symptoms of hepatitis or other liver injury): Discontinue immediately and perform comprehensive hepatic work-up. If LFTs return to normal, may cautiously consider restarting therapy with frequent LFT monitoring.
Signs or symptoms of hepatitis or hepatic injury: Perform comprehensive hepatic work-up; discontinue permanently if liver injury is confirmed.
Remove vial and diluent from refrigerator approximately 10 minutes prior to administration. Reconstitute each vial with 1 mL SWFI. Aim diluent along glass wall of vial, do not inject diluent directly on powder. Gently swirl solution in order to dissolve powder; do not invert the vial or shake the solution. After reconstitution, each vial will contain 10, 15, 20, 25, or 30 mg/mL of pegvisomant. Use only 1 dose per vial.
SubQ: For SubQ administration only; to minimize the risk for lipohypertrophy, rotate injection site daily; if 2 injections are required, select a different injection site for second injection; may administer in upper arm, thigh, abdomen, or buttocks; do not rub injection site. Do not use on area of skin with rash, lumps, bruising or on broken skin. The manufacturer recommends the initial dose be administered under the supervision of prescribing healthcare provider.
Store intact vials under refrigeration at 2°C to 8°C (36°F to 46°F); protect from freezing. Following reconstitution, use within 6 hours. Do not use reconstituted solution if cloudy or foaming.
Drug Interactions
Blood Glucose Lowering Agents: Pegvisomant may enhance the hypoglycemic effect of Blood Glucose Lowering Agents. Monitor therapy
Macimorelin: Growth Hormone Products may diminish the diagnostic effect of Macimorelin. Avoid combination
Opioid Analgesics: May diminish the therapeutic effect of Pegvisomant. Monitor therapy
Pegloticase: May diminish the therapeutic effect of Pegvisomant. Monitor therapy
Pegvaliase-pqpz: PEGylated Drug Products may enhance the adverse/toxic effect of Pegvaliase-pqpz. Specifically, the risk of anaphylaxis or hypersensitivity reactions may be increased. Monitor therapy
Somatostatin Analogs: May enhance the adverse/toxic effect of Pegvisomant. Specifically, this combination may increase the risk for significant elevations of liver enzymes. Monitor therapy
Test Interactions
Interferes with measurement of serum GH concentrations by available GH assays; commercially available GH assays will overestimate true GH levels
Adverse Reactions
Central nervous system: Pain (8% to 14%)
Gastrointestinal: Diarrhea (≤14%), nausea (≤14%)
Hepatic: Abnormal hepatic function tests (4% to 12%; >10 x ULN: ≤1%; ≤15 times ULN: <2%)
Immunologic: Antibody development (17%; non-neutralizing anti-GH antibodies; relevance unknown)
Infection: Infection (≤23%)
Local: Injection site reaction (4% to 11%)
Respiratory: Flu-like symptoms (4% to 12%)
1% to 10%:
Cardiovascular: Chest pain (≤8%), hypertension (≤8%), peripheral edema (≤8%)
Central nervous system: Dizziness (≤8%), paresthesia (≤7%)
Endocrine & metabolic: Lipohypertrophy (1%)
Neuromuscular & skeletal: Back pain (≤8%)
Respiratory: Sinusitis (≤8%)
Miscellaneous: Accidental injury (≤8%)
<1%, postmarketing, and/or case reports: Anaphylactoid reaction, anaphylaxis, angioedema, erythema, hypersensitivity reaction, increased serum alkaline phosphatase, laryngospasm, pruritus, skin rash, tumor growth, urticaria, weight gain
Concerns related to adverse effects:
• Hepatic effects: May increase liver function tests; transient but marked elevations (≤15 x upper limit of normal [ULN]) in transaminase levels, usually without accompanying hyperbilirubinemia, have been reported with use; transaminase levels often normalized following interruption of therapy; use with caution in patients with hepatic impairment; monitor hepatic function periodically during therapy; discontinue use immediately with confirmed liver injury.
• Lipohypertrophy: May occur following administration; daily rotation of injection site may prevent or reduce incidence.
Disease-related concerns:
• Diabetes: Use with caution in patients with diabetes mellitus; may affect glucose metabolism; monitor closely; dosage adjustments of antidiabetic therapy may be necessary.
Other warnings/precautions:
• Administration: The manufacturer recommends the initial dose be administered under the supervision of prescribing health care provider.
• Monitoring: Interferes with commercially available GH assays; do not make dose adjustments based on serum GH concentrations reported from assays; use insulin-like growth factor I (IGF-I) levels to adjust therapy.
Monitoring Parameters
GH-secreting tumor size, serum glucose in diabetic patients, serum IGF-I (every 4 to 6 weeks after initial dose and dosage change, every 6 months when normalized, and when multiple injections are converted to single daily injections).
Liver function tests (ALT, AST, total bilirubin, and alkaline phosphatase levels):
Normal: Monthly for first 6 months, quarterly for next 6 months, biannually for the next year
Elevated, but ≤3 x ULN: Monitor monthly for at least 1 year, then biannually for the next year
>3 x ULN: Withhold treatment; perform comprehensive liver function evaluation (rule out cholelithiasis or choledocholithiasis); if appropriate for treatment, closely monitor hepatic function and clinical status.
During therapy:
≥3 x but <5 x ULN without signs/symptoms of hepatitis, hepatic injury or increase in total bilirubin: Monitor weekly for further increases; perform comprehensive hepatic work-up
≥5 x ULN or transaminase ≥3 x ULN associated with any increase in total bilirubin (with or without signs/symptoms of hepatitis or other liver injury): Comprehensive hepatic work-up. If appropriate for treatment monitor closely
Pregnancy Risk Factor
Pregnancy Considerations
Adverse events have been observed in some animal reproduction studies.
Patient Education
• Discuss specific use of drug and side effects with patient as it relates to treatment. (HCAHPS: During this hospital stay, were you given any medicine that you had not taken before? Before giving you any new medicine, how often did hospital staff tell you what the medicine was for? How often did hospital staff describe possible side effects in a way you could understand?)
• Patient may experience diarrhea, common cold symptoms, injection site irritation, flu-like symptoms, back pain, nausea, rhinorrhea, or rhinitis. Have patient report immediately to prescriber signs of liver problems (dark urine, fatigue, lack of appetite, nausea, abdominal pain, light-colored stools, vomiting, or jaundice), dizziness, passing out, angina, severe headache, bruising, bleeding, swelling of arms or legs, or skin changes (HCAHPS).
• Educate patient about signs of a significant reaction (eg, wheezing; chest tightness; fever; itching; bad cough; blue skin color; seizures; or swelling of face, lips, tongue, or throat). Note: This is not a comprehensive list of all side effects. Patient should consult prescriber for additional questions.
Intended Use and Disclaimer: Should not be printed and given to patients. This information is intended to serve as a concise initial reference for health care professionals to use when discussing medications with a patient. You must ultimately rely on your own discretion, experience, and judgment in diagnosing, treating, and advising patients.
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text:
Karl Wiley basked in boxing glory after stopping his opponent in a 14-second first round flurry.
It was the first time in the ring for Karl, and his hard-hitting debut got plaudits from Sheffield's world champion Kell Brook.
But Karl, aged 36, of Queens Road, Sheffield, was not in the ring for glory – he did it for his grandmother, who was cruelly taken by Alzheimer's Disease.
Sheila Rose Concannon, of Arbourthorne, who had 10 children, 27 grandchildren and 22 great grandchildren, died aged 80 in March 2014 – but started to feel something was wrong aged 59.
She was diagnosed aged 63 and the disease took hold quickly.
Karl said: "She was surrounded by family and friends but she was always looking for her loved ones.
"We were right there with her but she did not know us, we were all strangers to her.
"What happened to my grandmother left a lasting impact on all our lives, we were all touched by this terrible disease."
Alzheimer's Disease is a physical disease that affects the brain. It causes damage to parts of the brain and symptoms develop including problems with memory loss, communication, reasoning, orientation and sometimes hallucinations.
Boxing is taking off as a hugely popular way to raise money for charities. Karl decided to get involved to raise money for the Alzheimer's Society in his grandmother's memory.
Karl, a media sales executive, hit The Sheffield Boxing Centre in Hillsborough, run by former city lightweight boxer Glyn Rhodes MBE.
But with top training comes the hard work and as Karl explains, it's no walk in the park.
Karl said: "It's such a great experience to get trained by top boxers. They teach you the basics like how to stand correctly and make you train like a professional.
"You don't turn up thinking it's going to be an easy ride, it's such an eye-opener.
"They tell you it won't be easy – you're going in to get punched after all – so you need to be ready."
After tasting victory in his debut bout, Karl has pencilled in another fight and is hitting the gym hard.
He said: "I'm really up for the next fight now, it's not long away I can't wait to get back in the ring again.
"But win, lose or draw I'll still enjoy myself because it's for a great cause."
Karl said his grandmother is still his motivation for success. He said: "As a kid me and various aunties and uncles would go up to her house and watch all the Saturday night TV. All of us would go and play football on the field in a big group and she'd come along with us. They were happy times."
Karl's next bout is due to take place at 3pm tomorrow at Sheffield United's Bramall Lane stadium.
For tickets contact Karl at firstname.lastname@example.com


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Kesito is a desk organizer that helps us to order those little objects that we always have on hand; pencils, paper clips, business cards and of course, our Smartphone.
If you can't see your desktop for the mess, but the idea of a sterile, tidy workspace is unthinkable, then relax we have designed a desk organizer that maintains the creative flow. Handmade in the Spanish region of Tierra de Pinares using sustainably sourced pine wood, the Kesito Desktop Organizer is made up of three diamond-shaped blocks that can be arranged in a row, a hexagon, or separately. One piece can hold a forest of upright pens, one is slotted for cards, notes, and smartphones, and the third is the perfect spot for pins, paper clips, and other small bits and bobs. Get organized without losing the inspiration of creative chaos.
We combine the know-how and knowledge of the craftsmen with innovative proposals of designers creating products with personality, that are elegant, timeless, and respect the environment, manufactured one by one by the craftsmen of Tierra de Pinares (Spain).


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New Mexico is amongst 31 states that have reached a settlement with three nationwide credit reporting firms that have agreedaccepted fix contested info on credit reports more rapidlyquicker, wait longer prior to including potentially destructive details and make other modifications.
Under the settlement, Equifax, Experian and TransUnion likewise will certainly pay a combined $6 million to getting involved states.
Its a good day for all consumers in the United States, stated Ohio AttorneyAttorney general of the united states Mike DeWine. He pioneered the investigation that led to the deal after reading a 2012 examination by The Columbus (Ohio) Dispatch about consumers rejected vehicleauto loan, residence loans and tasks due to the fact that of errors by reporting firms.
Other lawyers generalattorney generals of the united states applauded the deal.
This settlement is a crucial step that offers substantial protections for customers in New Mexico, New Mexico AttorneyAttorney general of the united states Hector Balderas said in a statement Tuesday. We negotiated for many years to attain these modifications, and the outcomes of our efforts will put higher control in the hands of New Mexico customers over this essential piece of their monetary lives.
The contract requires companies to:
Preserve information about issues with entities that furnish them information– such as collection firmsdebt collection agency, department shopsoutlet store or banks– and make that details readily available to states so patterns can be identified;
Utilize a better, more in-depth system to share data with those so-called furnishers;
Set up a more extensive procedure for complex disputes, such as those involving identity theft, fraud or mixed credit files where 2 peoples identities have actually been puzzled;
Inform consumers about how they can even more contest the result of an examination.
The settlement restricts credit reporting companies from including information about fines and tickets to a consumers credit report and bars the addition of medical debt till 180 days after it is reported to offer customers time to work with their insurance coverage companies.
It likewise allows customers to acquire an additional free credit report in a 12-month duration if a charge they challenge ends up to lead to a modification to their report. Federal law currently enables customers of getting a free copy of their credit report once a year from each of the 3 reporting firms.
The three nationwide credit reporting firms have been in compliance with federal and state law, however as we revealed in launching the National Customer Assistance Plan, we do not hesitate to make enhancements beyond what the law needs when doing so will certainly benefit consumers, stated Stuart Pratt, president and CEO of the Consumer Data Market Association, which represents the credit reporting firms.
Pratt stated the most recent thorough government research discovered credit reports are materially precise 98 percent of the time.
Other states in the settlement were Alabama, Alaska, Arizona, Arkansas, Florida, Georgia, Hawaii, Idaho, Illinois, Indiana, Iowa, Kansas, Louisiana, Maine, Maryland, Massachusetts, Michigan, Missouri, Nebraska, Nevada, North Carolina, North Dakota, Oregon, Pennsylvania, Rhode Island, Tennessee, Texas, Vermont and Wisconsin.


text:
The NBA has made it official: Orlando Magic guard Victor Oladipo will be one of four players who will participate in All-Star Weekend's slam dunk contest Feb. 14 at Barclays Center in Brooklyn.
The Milwaukee Bucks' Giannis Antetokounmpo, the Minnesota Timberwolves' Zach LaVine and the Brooklyn Nets' Mason Plumlee also will complete in the contest.
Dedmon contributes
One of Dewayne Dedmon's best attributes as a player is his explosive jumping ability.
But his ability to elevate might not be as impressive as his talent for dealing with the ups and downs of an NBA...


text:
Lamborghini Aventador: Just Like a Prius?
When does a Lamborghini super sports car with 700 horsepower seem like a puttering Prius hybrid?
Perhaps when its 12-cylinder engine suddenly shuts down at traffic lights, then automatically starts up again when the light turns green and the driver is ready to go.
The Italian car maker is touting just such a feature on its new flagship model, the 2013 Aventador LP 700-4.


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Microsoft has been trying to reinvent itself for a few years in an effort to catch up to the market that grew up all around it because of its reluctance to change. Like any large industry leader, moving swiftly is not a strength. And, once a large organization gets comfortable with their position in the market, they prefer to sit back and survey their empire which causes them to forget what got them there in the first place. Microsoft is a good example of this, but there are other cases like Dell and Intel. When proliferation reaches critical mass, innovation decreases, technology becomes stagnate, and opens the door for a new champ.
Part of Microsoft's effort to reinvent itself has been through reorganization. Almost every quarter-end for the last couple years has been met with a shift in product group personnel and executives. During this time period I've seen a lot of good friends move to different positions. Some of them moved into areas completely different than where they spent the majority of their tenancy at Microsoft. And, still others left to take jobs outside of Microsoft. Some of those came from personal decisions, but a good amount was forced.
Paul Thurrott spent some time piecing together the news on the upcoming reorg along with some thoughts on how things might shake out. You can read it here: More Details Emerge in Coming Massive Reorg at Microsoft. Paul does a great job covering tidbits of news concerning Microsoft, but his primary focus, at times, is targeted more toward the consumer areas like devices and entertainment. As we experience what Microsoft has envisioned for their own future, these areas will likely converge and blur, so it's valuable for IT to understand the shifts that are coming in all areas at Microsoft.
However, it's also important to sum up news of a reorg as it relates directly to IT now. A lot of IT Pros probably consider news of a Microsoft reorg to have very little to do with the fundamentals of their daily tasks. But, that's not entirely true. As Paul stated in his article, Satya Nadella will probably be an instrumental chief after the reorg, providing executive management over the services division. Satya has been with Microsoft since 1992, but in 2011 was named the president of the Server and Tools division, which includes System Center.
Related: Truth in IT: The Cloud is IT's Kobayashi Maru Moment
We already know that Microsoft is undertaking a massive Cloud movement, developing a mirrored image of on-premise capability in Windows Azure, and we know that Microsoft announced the "Cloud-First" development strategy at TechEd 2013 North America, but with another new reorg coming, and a hardened focus on devices and services, there could be many shifts for IT to watch out for.
Some of those that come to mind are:
- Licensing– With every new reorg there has been accompanying changes in how on-premise and Cloud services are licensed. Watch for changes over the next six months to make Windows Azure even more appealing by making it cheaper to use and maintain than on-premise solutions. Yes, this whole PRISM thing has a lot of companies drawing back like they just stepped on a rattlesnake, but if the price is right…
- Cloud devices– To me, this is one area that Microsoft could take a stab at. At TechEd 2013 North America there were many Expo vendors who had put together turnkey Cloud solutions using their own hardware but software from Microsoft. Microsoft's foray into building their own tablets (Microsoft Surface) is allowing them to cut their teeth in an industry for which they are infants. Microsoft matures quickly. The ability to purchase equipment, plug it in, and be up-and-running in 15 minutes or less is appealing for a lot of customers. Who knows? Maybe we'll see something along the lines of an Xbox-like Cloud device. It could happen.
- A renewed Public Cloud push– We've known for a long time that Microsoft's ultimate goal is to become the utility company for the Cloud. This goal is not going to change, only become more prominent with every internal reorg. And, while Microsoft is doing extremely well promoting the Hybrid Cloud as a business alternative, this is just a stop-gap measure to ensure that customers become comfortable with utilizing a Public Cloud by being able to automate offloading (outsourcing) technology workloads.
It'll be interesting to see how this all shakes out, but don't think for a minute that the reorg will not affect at least some area of IT in the near term. What do you think will happen due to the upcoming reorg? Do you care?


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How Starbucks Can Use Internal Weekly Email Digests to Connect with Employees
Before I became a designer, I was a barista at Starbucks (typical of people who don't know what to do with their lives). Although it's one of the best companies to work for and I had an amazing team, one of the problems I've encountered repeatedly over the years still remains unsolved: How do you get employees to take advantage of Starbucks's 401k match? I still run a blog for baristas and have friends at Starbucks, so it'd be amazing if I could help them out.
Fortunately, I think this is a problem where an email digest can help (… but I'm probably biased, for obvious reasons).Â
The big problem
Starbucks's benefits package includes a generous 4-6% 401k match for part-time employees. This is so good, it's unreal… it makes Starbucks one of the few part-time jobs where employees can actually save money! But it only works if people actually take advantage of it. From my experience, employees know of it, they may even want to do it… but most fail to.Â
I once worked with a co-worker in her mid 50s who was struggling to cover her bills, and wanting to help, I asked if she had been contributing to her 401k (because you can take a low-interest loan from it). She'd been employed for almost 10 years so I assumed she must had a decent chunk saved up, but it turns out she had never started her retirement plan! She's a warm lady who survived breast cancer, so I was very saddened to hear about her predicament.
And she wasn't the only person who failed to set up their 401k. In fact, I met so many people who "didn't understand it" or "never got around to it" that I decided to write an unofficial guide to Starbucks's 401k (It now ranks either 1st or 2nd when you Google "Starbucks 401k.")!
This happens because employees lack the mental bandwidth to "figure it out" and fall victim to the status quo bias. This shouldn't be a surprise, because being a Starbucks barista is actually more difficult than you'd think, and many employees also go to school or have 2nd jobs.Â
They actually do get a piece of physical mail with information about this, but it happens once a year (I think), and then they have to set up their 401k plan online. Switching from physical to digital creates serious friction, especially if it's something they don't fully understand. And coupled with our natural planning fallacy, this means most people just never get around to it.Â
A smaller problem
Many employees lack trust in corporate. Starbucks is actually one of the most employee friendly companies, but it suffers from the same problem most large organizations have: lack of communication with front-line employees.
Most of the communications that came through were things we were REQUIRED to read. It felt like "corporate" was this distant entity that made our policies but had no direct exposure to customers like we did. In reality, Starbucks does its research, even going as far to as opening stealth stores to test new products — they know what they're doing (most of the time).Â
Sure, employees can go online and scan Starbucks headlines if they really want to. But this is a job, not a career to retail employees. Once they are off the clock, they stop working.Â
I believe a weekly digest email can solve these problems
Information about 401k and Starbucks news can be sent through email in a weekly digest. I think this will be effective because:
1.) The higher frequency (compared to physical mail) will ensure 401k (as well as other benefits) stay on top-of-mind. Taking action also becomes easier because you're already online.Â
2.) Regular communication with corporate will slowly build trust with employees.Â
The issue then becomes getting employees to open these emails. Because they stop "working" once they're off-the-clock, they're going to ignore these emails unless there's something they really need. And let's be honest… it's not very exciting to read an email about benefits and Starbucks news.Â
So how do you get employees to "work" outside of work?
The solution: include their weekly schedule in the email.Â
Baristas almost never get the same schedule week-to-week and occasionally they'll forget when they work or show up at the wrong time. Having a digital copy would be a HUGE immediate utility and will guarantee this email gets opened multiple times throughout the week.Â
And, they'll LOVE Starbucks for doing it.Â
This is how it could look like:
I actually showed this to baristas and the response has been great!
One reader responded:
Are you okay with me talking to someone who can actually do something to make that happen? I am a current partner who works at a Seattle store rather close to the Support Center. We get people from almost every department in our store and on a few occasions they have listened to us and our problems and fixed them. I would love to see your email idea happen and I know it would help so many people.
There we have it — it's a win/win.
I hope Starbucks makes it happen!
Although I wrote this specifically for Starbucks, the same principles apply to many other organizations. An internal digest can be an ideal medium to send timely reminders and company communications. Can your organization benefit from a weekly digest?


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text:
Charles and Ray Eames
Charles (1907–1978) and Ray (1912–1988) were two of the most important and influential designers in post-war America. Creating some of the most famous pieces of 20th century furniture, such as the Eames Lounge and Ottoman and the series of Eames Aluminium Group Management Office Chairs, their designs today are as popular as they were in the last century.
Lounge chair with Hocker Lounge€ 998.00
dining chair DSX matte€ 69.00
dining chair DCM€ 197.00
office chair EA117 Hopsack
Regular Price: € 534.00
Special Price: € 420.00
children's chair DSW junior transparent€ 49.00
dining chair DSX upholstered€ 99.00
children's chair Puppy chair small
Regular Price: € 54.00
Special Price: € 36.00
barstool DSW Eifel barstool upholstered€ 107.00
lounge chair Lounge€ 799.00
ottoman Lounge€ 199.00
dining chair DSS matte€ 69.00
office chair EA117 mesh netweave€ 299.00
office chair EA117
Regular Price: € 449.00
Special Price: € 399.00
dining chair DSW matte€ 59.00
dining chair DSR matte€ 59.00
dining chair DSR Black base matte€ 59.00
dining chair DSW Transparent€ 99.00
dining chair DSR Transparent€ 99.00
dining chair DAR Transparent€ 99.00
dining chair DSR upholstered€ 99.00
dining chair DSR Black base€ 107.00
game chair Aaron mesh netweave€ 499.00