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An abscessed tooth is an infection, or a collection of pus within the pulp (inner part of tooth). The pus, or abscess, is enclosed in the tissues of the jaw bone, as well as at the tip of the infected tooth. In most cases, an abscess tooth is the result of tooth decay, but there are numerous reasons why an abscess tooth forms.
There are three types of abscess teeth: a gingival abscess, periapical abscess and a periodontal abscess. The gingival abscess occurs in the gum tissue only, not affecting the tooth or the periodontal ligament. The periapical abscess is found in the dental pulp and the periodontal abscess occurs in the supporting bone and tissue structures of the teeth.
A tooth abscess needs to be treated as soon as possible. If it isn't, it can lead to serious, life-threatening complications. Prevention of abscess teeth is key to maintaining proper oral health.
Tooth Abscess Symptoms
If you have an abscess tooth, chances are you'll be experiencing serious symptoms, including:
- Severe toothache that will not stop throbbing
- Increased sensitivity to hot and cold
- Fever
- Sensitivity when biting or chewing
- Swelling in face, cheeks and lymph nodes (located under your jaw or in your neck)
- Taste of pus or infection in your mouth
- Foul-smelling odor from the infection in your mouth
You will definitely be able to tell if your tooth is an abscess or not due to the factors listed above. The pain is severe and refuses to go away. You will be able to taste the bacteria filled pus that is oozing from the infection if the abscess tooth is left untreated. Some people also experience nausea and vomiting due to the bacteria invading the body.
When to See the Dentist
You should see your dentist twice a year, or every six months to ensure your oral health is in good condition. If you do not see your dentist regularly, and you are having symptoms of a tooth abscess, you should make an appointment immediately. A tooth abscess can go from bad to worse within hours, so seeking medical attention is critical to avoid the symptoms listed above. If your dentist is unavailable and you are experiencing a fever and swelling in your face, you should go to the emergency room. Fevers and swelling are indicators that the infection has spread deeper into the jaw, bones, surrounding tissues, and other parts of your body.
Tooth Abscess Causes
The number one cause of a tooth abscess is poor oral hygiene. Abscess teeth occur when bacteria has the chance to build-up and enter into the dental pulp. The dental pulp is the most important part of each tooth, where the blood vessels, nerves and connective tissues are. Bacteria invades the dental pulp through a number of different ways such as through a broken, chipped or cracked tooth, through a dental cavity, or it may be able to enter a persons system due to an underlying autoimmune disorder such as Sjogren's Syndrome.
Other causes include:
- Trauma to the tooth or mouth
- Medical conditions that weaken the immune system, such as diabetes
- Gingivitis
- Gum disease
Abscess Tooth Treatment
The first thing your dentist will want to do is take panoramic x-rays to see how bad the abscess is, or to see if it has spread to other parts of your mouth, such as into your jaw bone. Treatment involves eliminating the infection and draining the pus or bacteria from the tooth. Drainage can happen three ways: root canal, incision or tooth extraction. Extracting the tooth allows drainage, but doesn't allow you to save the tooth. Dentists try to preserve teeth by performing root canals, but sometimes root canal surgery may be required to remove diseased root tissue. Your dentist may consider draining the abscess by means of an incision into the swollen gum tissue.
Antibiotics may also be prescribed to help fight the infection and to prevent or stop the infection from spreading further. Many times, over-the-counter pain medication such as Ibuprofen or Tylenol can help reduce pain, fight infection and reduce swelling.
Preventing Tooth Abscesses
Preventing a tooth abscess is simple. All you have to do is maintain proper oral health by brushing your teeth, flossing and rinsing at least twice a day. Plus, you have to continue to see the dentist every six months. Regular check-ups are a great way to detect problems early or before they turn into abscess teeth. Your dentist may be able to fill a cavity or give you a good cleaning during your visits. Either way, your dentist will be able to spot problems, conditions and diseases during their early stages. Another key prevention tip is if you are injured or trauma occurs to your teeth, seek dental care. Bacteria can invade your teeth quickly, within minutes of being exposed to uninfected area.


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Source: Reuters / The Huffington Post
WASHINGTON – The United States said on Wednesday that U.S. citizens were among the hostages taken when Islamists raided a gas facility in Algeria and that U.S. Secretary of State Hillary Clinton had telephoned Algeria's prime minister to discuss the incident.
"Beyond confirming that there are Americans among the hostages, I will ask you to respect our decision not to get into any further details as we try to secure these people," State Department spokeswoman Victoria Nuland told a news briefing.
Nuland said Clinton had spoken with both Algerian Prime Minister Abdelmalek Sellal and the U.S. ambassador in Algeria on Thursday, and that U.S. officials were also in contact with the security office of British Petroleum, which operates the gas field together with Norway's Statoil and Algeria's state company Sonatrach.
To read this article in its entirety visit The Huffington Post.

subset: commoncrawl


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One thing about eating differently that is difficult is that you want some things that you are used to. I have tried a lot of new foods, but my favorites are still the stuff that were basic staples in my diet. Alfredo noodles were one of those things!
Who doesn't love the creamy goodness? Well, now my tummy doesn't! So here is a different version of the cheesy classic that makes me (and my tummy) happy!
You Need:
- 1/4 cup vegan margarine ("Earth's Balance" is what I use)
- 1/2 tsp. minced garlic
- 2 cups cooked (or 1-15 oz can, drained and rinsed) white beans
- 1 1/2 cup plant based milk (I used Unsweetened Original Almond Milk, because it's what I had in the fridge)
- salt, pepper, parsley, and garlic powder: to taste
In a medium saucepan, simmer on low heat butter and garlic for 2-3 minutes. Transfer to a blender and add the beans and 1 cup of the milk. Blend until smooth. If it is too thick, or you don't like the texture, slowly keep adding milk (a little at a time), and blending to find your desired consistency.
Once you are content with the consistency, pour it back in the saucepan and turn the heat on low. Add seasonings to taste. Cook it til warm, stirring frequently. Toss it on half a box of cooked whole grain pasta.
The flaw with this recipe is that it doesn't make a lot (it covers a half of a box of cooked pasta well, but if you make more pasta, you would want to double it.) Something you can do is buy the plant based milk when it's on sale. Some varieties of plant based milk are in the dairy section of the grocery store; some are in the cereal aisle. Check the cereal aisle if you know you'd like to have this sauce but not sure exactly when you are going to have it, because you can store that milk (as long as it hasn't been opened) in your pantry, freeing up much needed fridge space. Once you open up your plant based milk, either the milk from the cereal aisle or the dairy section, it needs to be used up within 7-10 days.


text: Google trying to get another piece of your life. Code: "With infinite storage, [B]we can house all user files[/B], including: emails, web history, pictures, bookmarks, etc and make it accessible from anywhere (any device, any platform, etc). We already have efforts in this direction in terms of [B]GDrive[/B], GDS, Lighthouse, but all of them face bandwidth and storage constraints today."


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Separate names with a comma.
Discussion in 'iOS 7' started by CosmoPilot, Aug 16, 2013.
Did Beta 6 delete iRadio for anyone else? Does the configuration profile bring it back?
iTunes Radio is still there for me.
It came back after 2 soft resets.
This hasn't changed...My problem with itunes Radio is this: in order to use it on the road you have to allow cell data here:
So, I have to have all else turned off, because, if I have automatic updates on, it will update my apps, using cell data, while on the road, when all I want is cell data for iRadio!
I'm trying to find a way to suggest to apple so that they actually change it, it's quite a big deal...
If they want me to use iRadio, they have to make it so I can turn cell data on ONLY for iRadio and not iRadio AND iTunes Match AND automatic updates, it's just so stupid...anyone that uses this much cell data will either go over their monthly plan or go high enough to get "throttled".
I want to be able to use automatic downloads for updates while on wifi only.
I want to be able to use iRadio on wifi or cell data.
There is no way to set it this way.
Under cellular try disabling AppStore ... That may work as a workaround for now


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Emotions Captured in Illustrations That You Can Almost Feel!
Ever heard the saying "A picture is worth a thousand words"? The works of this Korean Illustrator named Zipcy are the perfect proof that an image, a picture, a drawing is much more than just that. Zipcy's work captures emotions with such perfection that you will feel the emotions presented in each one of her illustrations.
Meet Zipcy whose real name is Yang Se Eun, a 29-year-old artist from Seoul, South Korea.
Zipcy is an illustrator who loves to show emotional sensitivity in her drawings. You can almost feel the love reflected in each one of her illustrations below. Or very well guess what the characters in her drawings would be thinking or feeling in that moment. It's truly an amazing work where each piece it's worth more than a thousand words. Here's my take on the first impression I get when I see each illustration.
"Let me feel your heart beat and keep it forever."
"I love the way you caress me."
"I'm lost without you."
"I need you by my side."
"I can feel you love my touch."


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Help: What is unsent complement data?
Some data may temporarily be stored on your phone if your connection is slow while broadcasting live. Upload this data afterwards to smooth out the archived broadcast.
Being truly LIVE is the most important aspect of Bambuser broadcasting, and our mobile applications are therefore written to adapt to the varying upload speed of mobile networks. If broadcasting using the chosen quality settings produces more data than your connection can send live, parts of the data may be stored temporarily on your phone instead. This allows us to keep latency at an absolute minimum at all times while you are live and still provide smooth video for later viewing.
Stream health bar in Android app
Unsent complement data in iPhone app
The stream health concept
Our newer applications include a stream health bar showing how much data is actually sent live. A high stream health suggests that most or all of the data is sent live, and your viewers get a smooth experience. A low stream health suggests that your connection is not fast enough for the quality settings you have chosen and your viewers may experience choppy video.
If your network connection is very fast and your stream health is constantly high, it suggests that it could handle even better quality video, and you can consider raising the video quality under Settings. You may of course use as low settings as you wish, to conserve bandwidth, which can be useful if your mobile data contract has a monthly data limit.
Unsent complement data
If some data can not be sent live, it can be stored in your phone, provided that you have the feature enabled. This data is not in any way a complete recording, but only contains parts that weren't sent live, a complement to the live broadcast. This means that it doesn't occupy any more space than necessary.
Uploading unsent data
You may upload any stored unsent data at any time after broadcasting live. The mobile application contains a list of any unsent data, where you can choose whether to complete a particular broadcast right now, upload everything at once or delete data you no longer need (for example if you have already removed the archived broadcast).
When you have uploaded the unsent data for a broadcast, our servers will combine the live-data with the uploaded data, put all the data in the right order and create a smoother broadcast that can be viewed on demand.


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This page contains videos and articles on the accessories that can
be used to complement crystal energy. These include oracle and
crystal cards, candles, pendulums, and essential oils.
The Many Uses of Crystal Oracle Cards
Achieving Goals with Candles and Crystals
Working with Pendulums & Crystals
How to Store and Display Your Crystals
Healing Through Scent: Eucalyptus
Healing Through Scent: Lavender
Aromatherapy for Autumn
How to Decorate with Crystals Video
How to Choose a Pendulum Video
How to Use Crystal Oracle Decks ideo
How to Use Crystals for Animal and Angel Oracle Cards Video
How to use Pendulums for Divination Video
Uses for Candles Video
Check out more great information in our Beginner's Reference Guide!


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GREEN TOWNSHIP, OH (FOX19) - A man was arrested over the weekend in Green Township who police say was found hiding in an enclosed porch wearing socks on his hands.
According to the Green Township Police Department's Facebook page, Jason Crabb, 32, was reported as 'suspicious' by a resident in the 5600 block of Muddy Creek Road on Saturday morning. A neighbor told police he was wearing a backpack and walking around a home in the area.
Upon arrival, an officer found Crabb hiding in the porch area of the residence. A wrench, socket set, and a hypodermic needle were discovered in his backpack.
Crabb reported being homeless and walking to Green Township from Clifton.
He was charged with burglary, possession of criminal tools, and possession of drug abuse instruments.
He was taken to the Hamilton County Justice Center where a judge set his bond at $70,000.
Copyright 2013 WXIX. All rights reserved.


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LavAzza Classico K-Cups [16/box]
LavAzza Classico K-Cups utilize a special start-stop roasting method to create this blend with a signature intense aroma of dried fruits along with a rich and full-bodied flavor. Classico is medium roasted featuring coffees from Brazil and Africa, perfect to enjoy as part of your everyday coffee ritual.
Important Note: These K-Cups are only compatible in coffer makers designed to accept Keurig K-Cup style capsules (including the new Keurig 2.0 machines). They DO NOT fit any other type of coffee maker or espresso machine.
- LavAzza Classico KCups
- medium roast
- box of 16 capsules
- Italian coffee, packaged in USA
- for your reference: 1 case = 10 boxes
Be the first to rate this item!


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Aston at the Waikiki Banyan is surrounded by a wide variety of dining options. Whether you're looking for romantic ambiance to celebrate a special occasion or a hole-in-the-wall with delicious local fare, there is always something within walking distance to suite your taste.
Banyan Breeze Coffee Company
Open daily from 5:00am to 7:00pm.
Lobby Level
Call (808) 923-2733.
Casual attire.
Kickstart your day. Banyan Breeze is the perfect spot for espresso drinks, smoothies, and a variety of light fare including pastries, sandwiches, salads and wraps.
Banyan Snack Bar
Open Monday-Saturday from 11:00am to 7:00pm and Sundays from 11:00am to 4:00pm
Located on the 6th Floor Recreation Deck
Call (808) 931-3620
Aston Waikiki Banyan boasts the best and largest recreation deck in Waikiki. Take a break from lounging poolside and join us for our wide variety of ono plate lunches, snacks, smoothies, and shave ice.
Tiki's Grill & Bar
Aston Waikiki Beach Hotel
2570 Kalakaua Avenue
Open Monday-Saturday from 11:00am to 7:00pm and Sundays fr.
Call (808) 923-8454.
Casual attire.
Located just a short 5 minute walk away at the Aston Waikiki Beach Hotel, Tiki's Grill & Bar is a hip, open-air eatery reminiscent of the iconic tiki bars of the 1950s and 60s. Tiki's features an eclectic Pacific Rim menu with delectable island flavors. Join us nightly for live contemporary Hawaiian entertainment.
Grocery Delivery Service
Don't waste your vacation at the grocery store! Island Grocery Service can stock your kitchen for you before your arrival. Visit islandgroceryservice.com to place your order.


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'Some stories are just so good, you can never let them go.' This is something all TV series fans would agree with. The character developments and the story lines of some TV shows are so amazing that we bond with them as if it's a real life story. Because of this, once you watch a great TV series, it's hard to resist watching it for a second, third time or as many times as you like.
This article talks about some of the best TV series you don't see on screen anymore, but will remain in our hearts forever, yet still using megamovies to watch free tv shows online it's possible to remind a bit on them.
Friends (1994-2004)
From its catchy theme song to the great casting, everything about Friends was amazing. The series, directed by David Crane and Martha Cauffman started in the year 1994 and aired on NBC for 10 years or 10 seasons with a fan base that grew each day.
The story was about a bunch of (6) friends who led interesting lives in their New York City apartments. Monica (Courtney Cox Arquette), Joey (Matt LeBlanc), Rachel (Jennifer Anniston), Chandler (Matthew Perry), Phoebe (Lisa Kudrow), and Ross (David Schwimmer) are characters everyone still misses even12 years after the show ended. By time the last episode aired, Friends gained up to 52.5 million viewers and is the last sitcom to be ranked No. 1 on television.
Lost (2004-2010)
Lost is a TV series about a group of survivors of a plane crash work together for their survival on a deserted island. This American TV series started in 2004 and aired for 6 years with 6 seasons and a total of 121 episodes on the ABC channel. Falling in to the Sci-Fi and supernatural genres, the story was loved by many people. The creation credits of Lost go to J.J. Abrams, Jeffery Lieber, and Damon Lindelof.
The season one of the series had an estimate of 16 million views while in the last season the viewers were over 11 million. The show won many awards like the Emmy Award for Outstanding Drama Series in 2005, Golden Globe Award for Best Drama in 2006 and was named the TV series with the highest rating in the first 10 years (2002-2012) of IMDB Pro.
How I Met Your Mother (2005-2014)
The story starts with Ted Mosby (Josh Radnor) recounting the story of how he met their mother to his two children in the year 2030. From then his story continues with the flashbacks of his life in Manhattan with his 4 best friends Marshall Eriksen (Jason Segel), Lily Aldrin (Alyson Hannigan), Barney Stinson (Neil Patrick Harris), and Robin Scherbatsky (Coby Smulders).
Ted's search for 'The One', Lily and Marshall's never ending love story and Barney's jokes kept the audiences entertained for 9 years and 9 seasons of the show with the ultimate hope of finding out how Ted met his wife. The series creators were Carter Bays and Craig Thomas who received the inspiration for the story from the period they lived in the New York City as friends. Winning 9 of the 28 Emmy nominations the series received, HIMYM also won People's Choice Award for Favorite Network TV Comedy in 2012. Although the ending of the story received mixed reviews, the fan base of the series grows to this date.


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'Twas the Week Before Christmas (Harlequin Special Edition Series #2304)
Paperback(Mass Market Paperback - Original)
A romantic inn
a white Christmas
hot cocoa by a roaring fire
it all adds up to a perfect holiday romance from Special Edition debut author Olivia Miles!
Dear Holly,
As I look around the inn, I see garland and mistletoe, colored lights and ornamentseverything I have always professed to despise. You were right to wonder why I would choose to visit the White Barn Inn. You were right about a lot of things.
Since I met you, though, everything has changed. I've changed. And that's why I can't go on any longer without telling you the whole story. I don't know if you will ever be able to forgive me. But they say Christmas is a time for miracles. And you do believe in them, don't you? The question is, can you still believe in me?
Product Details
|Publication date:
|Harlequin Special Edition Series , #2304
|Edition description:
|Product dimensions:
|4.34(w) x 6.64(h) x 0.62(d)
About the Author
Olivia loves hearing from readers. Visit her website, www.oliviamilesbooks.com.
Read an Excerpt
"Looks like a storm's about to roll in."
"So I heard," Holly Tate murmured distractedly. Furrowing her brow, she studied the reservation list and then glanced at the hands of the old grandfather clock at the base of the stairs. There was still one guest unaccounted for, and the dining room would be closing in fifteen minutes. Well, she'd have the chef hold a turkey sandwich and a slice of apple pie. She could always send it up to the guest's room upon check-in, just as a courtesy. Exceptional customer service was something she took seriously, and while a few minor complaints were inevitable, The White Barn Inn had yet to receive a bad review on any travel website Holly knew of. The repeat customers she saw year after yearand the referrals they providedalways filled her heart with a sense of pride and warmth.
"They say we should get three or four inches tonight," the assistant manager and housekeeper, Abby Webster, continued. "Steady through the morning and afternoon, but the Nor'easter's expected to hit tomorrow night."
Holly finally glanced out one of the tall, lead-paned windows that framed the front door. Large flakes of snow were falling steadily on the vast stretch of lawn that separated the old mansion from the main road. There would be no sense in asking the handyman to clear the path; it would be covered again in half an hour. It would have to wait until morning.
"We're still waiting on one guest," Holly informed her friend. Though she was Abby's employer, the two women were also good friends. Life at the inn was quiet and occasionally confining, resulting in long days, weekends, and holiday hours. After leaving Boston five years ago to transform the large historic home she had inherited from her grandmother into a bed-and-breakfast, Holly had retained fond memories of riding bikes or lining up at the candy store on Main Street with Abby during her annual summer visits to her grandmother's house in Maple Woods. Having lost touch years before, the friends had picked up where they had left off and grown even closer since.
"Do you want me to stick around until he arrives?" Abby asked halfheartedly.
Holly shook her head. "You go home to that handsome husband of yours," she said. "Besides, I don't want you driving in this kind of weather at night."
"The streets should be plowed by the morning." Abby stifled a yawn and pulled her red wool pea coat off the wrought-iron rack next to the front desk. She shrugged herself into a hand-knitted creamy wool hat and wrapped a matching scarf tightly around her neck. "Don't stay up too late."
"Have a good night," Holly called after Abby, pulling her cardigan tighter around her waist as a cold gust of wind rushed through the open door. The flames that were burning high and steady in the fireplace in the adjacent lobby flickered precariously. Holly wove her way through the oversize sofas and chairs, pausing to plump a pillow and refold a chenille throw, and then added another log from the neatly packed pile at the side of the brick hearth.
She checked her watch again. Ten minutes until the kitchen closed. Stephen, the chef, would be eager to get home, especially in this weather. Inside the dining room, another large fireplace crackled invitingly, casting a warm, golden glow on the four couples hunched over their desserts and savoring the last sips of their red wine. Conversation was low and intimate, and Holly silently crossed the polished floorboards to the kitchen where inside a clattering of pots and pans posed as a sharp contrast to the serenity of the other areas of the inn.
"We've got a straggler," Holly said, grabbing a Christmas cookie from a tray and taking a bite.
"Those are for the guests!" Stephen chided, throwing a white dishtowel over his shoulder.
"You know me." Holly laughed. "I can never resist your gingerbread. Besides, it's only a few weeks out of the year, so I'm entitled. I'll hit the gym in January."
"Sure you will." Stephen smiled, knowing all too well that this was not true. Holly had only been saying this every Christmas season since the inn had officially opened for business four and a half years ago, and she still had every intention of following throughif she ever managed to find the time. Running the inn had become her life and she poured everything she had into doing her job well. There was little time for anything else. Or anyone else, as Stephen also liked to point out.
"Do you mind putting together a tray before you go? A turkey sandwich and a slice of pie would be perfect."
"Are we sure this person is even going to make it in tonight?" Stephen pulled a loaf of sourdough from the basket on the counter and began slicing two thick pieces. "It's getting bad out there."
"Maybe not, but even if he's already tired from a long drive, he might want a little something." Holly perused the variety of cookies and plucked a dried-cranberry-and-nut variation off the platter. She took a quick bite, casting a furtive glance in Stephen's direction. Delicious. "Besides, this particular gentleman is staying in the Green Room."
"Ah," Stephen said, laying a wedge of cheese on top of a round of heirloom tomato. Every room in the inn was named after the color of its walls, and the Green Room was the best suite in the house, right down to its king-size bed, steam shower and private balcony. Abby liked to joke that it was named the Green Room because it reeked of money, but Holly had chosen the color specifically because of the way the leaves from the trees grazed its third-floor windows in the spring.
"I should go and see if he's arrived yet," she said, dusting the cookie crumbs off her hands. "Thanks again for putting something together."
"No problem," Stephen said. "See you tomorrow afternoon."
Holly retraced her steps to the front lobby, noting with a stir of childish glee the way the holiday lights, wrapped around garland framing each window, glowed like stars in the dimly lit room. Standing just to the left of the massive Christmas tree was a tall man hunched over the thick doormat, stomping the snow off his feet. His slightly wavy brown hair was wet and slick, and the shoulders of his black cashmere coat were dusted with fine white powder. At last!
"Welcome to The White Barn Inn," Holly said cheerfully, watching in slight dismay as the melting snow spilled over onto the cherry wood floors. She darted to the small reception desk to grab a rag, and returning quickly to the scene of the crime, she sopped up as much of the icy water as the cloth would hold.
"I'm afraid I've made a bit of a mess."
"Oh, no it's fine," Holly said easily, still fixated on her task. "Just a little water, no harm done. There." Once satisfied that the damage was under control, she stood to formally introduce herself to the latecomer and found herself face to face with a shockingly handsome man.
"Sorry again." The guest grinned sheepishly, gesturing to the snow melting off his weather-inappropriate shoes. His turquoise eyes flickered with boyish charm.
Holly struggled to compose herself, finally finding her voice. "Good to see you arrived safely. These roads can be treacherous if you aren't used to them."
"No, I'm fine," the man said mildly. He swept a hand through his damp hair and followed her over to the reception desk. "Believe it or not, there's a country boy hiding under this city slicker." His grin widened.
"That makes us opposites, then. I was born and raised in Boston. I've been in Maple Woods for five years now and I'm still terrified of driving in the snow, especially at night." Holly smiled.
"I'm Max, by the way. Max Hamilton. I'm booked for the next two nights. But then, you probably knew that."
Holly accepted Max's hand into her own, alarmed by the chill of his palm. The man must be freezing. "I had an inkling," she said, noticing how his skin warmed slowly from the heat of her own. The subtle intimacy made her feel instantly connected to him. "I'm Holly. Holly Tate."
"Pleased to meet you, Holly Tate."
Sucking in a nervous breath, Holly fished through the drawer for the key to the Green Room, noting the slight quiver in her hands, but happy for a diversion. Finally locating the familiar green keychain, she handed it over to its temporary owner and went through some of the routine information about the inn. The sound of her voice, on autopilot, filled the room, but her attention was on anything but breakfast hours or turndown services.
It had been a long time since she'd had the pleasure of being in the company of a man as attractive as Max Hamilton, and her stomach fluttered as she looked him over. She estimated him to be in his early to mid-thirtiesunmarried, she noted with a flip of her heart as he signed the registration book, left-handed, and devilishly handsome. Something about those electric blue eyes and that broad, kind smile made him instantly appealing.
"I'm past check-in, aren't I?" Max looked slightly alarmed at the realization. "I hope they didn't keep you at work on account of me."
Holly took in the friendly twinkle of his eyes and genuine, lopsided grin and felt herself inwardly melt. "Don't worry about it," she said. "And besides, they didn't keep me at work. I own the place."
Something in Max's demeanor shifted and the glint of his eyes turned murky for one quick, telling second. Holly wasn't surprised. No one expected a woman in her late twenties to be the proprietor of this establishment. She was often met with disbelief when she revealed this fact.
"Surprised you, didn't I?" she smirked, coming around the desk.
Max curled his lips into an irresistible smile. "You definitely did," he said.
Max Hamilton wasn't sure what to make of this revelation. What a strange profession for a woman as young as Holly. An innkeeper? In this remote little town? He had assumed that the owner of this quaint establishment would be an elderly retired couple, not the sexy young thing that stood before him.
He'd have to rethink his strategy.
"So you own all this?" he asked, gesturing to the lobby and the rooms beyond. It was clear that a lot of attention had gone into the furnishings and decor. The house was built in the colonial style, traditional with white siding and black shutters, but large and substantial. Coming up the main drive, he'd noticed the wreaths hanging from each window by a thick crimson ribbon, the inviting lanterns the hugged the front steps, the pine garland that wrapped the awning posts. Sweeping his gaze over holiday decorations that seemed to fill every inch of the foyer in which they stood, he had to wonder if that red front door had been painted especially for the holiday. Probably, he decided.
"That's right," Holly nodded and then stopped herself suddenly. "Well, almost. My family's been leasing the land for three generations, but I've been saving toward buying it when the lease is up."
Max raised an eyebrow. "That's a pretty substantial investment."
"You'd think so, but not in a small town like this. The Millers were the original owners of the land back in the early nineteen hundreds and the family has stayed in town for the most part. George Miller is the current owner now and he and his wife have no real use for the land, so luckily we've managed to come to an agreement."
"So then you were right the first time you answered my question," Max continued. "You really do own all this."
"Not yet," Holly corrected. "The lease was for ninety-nine years. It was a Christmas gift from my greatgrandfather to my great-grandmother. It expires next week."
"And then?"
"And then hopefully everything can be signed and sealed." Holly smiled, bringing a soft blush to her otherwise creamy complexion and a spark to her hazel eyes.
Max shifted his weight from his left foot to his right, unable to match her visible excitement. He grimaced at the water seeping from his black leather loafers onto the polished floorboards. "I'm doing it again," he warned, glancing at Holly from under the hood of his brow.
Holly laughed at his expression, saying, "Oh, I'm being rude babbling about the history of the inn when you've had such a long trip and probably want to get settled."
She bent down to pick up his luggage, but Max immediately stopped her. "I may be your guest for the evening, but I'm also a gentleman."
Holly's pale cheeks flushed with pleasure and she refused to meet his eye when she said, "I'll show you to your room, then. Follow me."
Gladly, Max thought, fighting off a suggestive smile. He did as he was told and followed her up the winding staircase to the second floor landing, and then up yet another set to the third floor. He couldn't resist taking in the curves of her figure, the slim waist and flare of her hips under her form-fitting black skirt. Her rich, chestnut brown hair brushed her back, swaying slightly against her narrow shoulders, and he traced his gaze down the length of her long legs as she carried herself silently up the red carpet-lined stairs, careful not to disturb guests who, it seemed, had already turned in for the night.
"Here we are!" she announced breathlessly, catching his eye. Max noticed how large and round her pupils were in the dim light, how her hazel eyes had darkened to moss, interrupted by flecks of amber. Her cheeks had a slight rosiness to them, and her lips were wide and tinted with the faintest touch of ruby lip gloss.
"You honestly planned to carry my luggage all this way?" Max grinned and reflexively winked.
Holly bristled and tucked a loose strand of hair behind her ear. For the faintest hint of a second, Max wondered if this was such a good idea, after all.
As a major retail owner and developer, Max and his team had pinpointed Maple Woods as the ideal location for the next major upscale shopping mall in their portfolio. The demographics were strong, and the location roughly halfway between New York and Boston made a compelling argument. He'd driven through Maple Woods and the four neighboring towns three times each in the last two months, and the thirty acres of land housing The White Barn Inn was the best site.
He'd come to Maple Woods tonight with his renderings in hand, along with substantial market and financial research to back up his pitch, prepared to meet with the planning board and make an offer to the owner of the inn that couldn't be beat. He'd assumed the owner would be a retired couple, happy to trade in long, relentless days of serving others for a life of comfort and financial security.
He had assumed wrong.
The owner of the inn was this bright, cheerful, drop-dead gorgeous creature. And something told him she wasn't going to walk away quietly. The owner of the land, on the other hand, could most likely be bought. There was no way Holly could top his offer, and George Miller would have to be a fool to turn down what Max was prepared to offer him.
Max rolled his luggage to a stop beside an oversize armchair near the far window. Looking around the perfectly appointed room with the white trim and soothing sage-green-painted walls, it was becoming increasingly clear that Holly had invested a lot of time and money into what had probably been a very old home in need of substantial work. The inn could hardly be pulling in enough to make her rich. And that only led to one conclusion.
She loved this place. She wasn't going to go down without a fight.
Unless, Max thought, I manage to convince her otherwise.
Customer Reviews
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Lovable Christmas read!! I loved it. It is a shorter story, but not too short, you really still feel like you get the whole story and nothing is rushed. Holly and Max are perfect for each other, both lonely and in need of that special someone to trust. Max is holding back some truths about why he is in Maple Woods at Holly's Inn. This is not a problem until he starts falling for Holly...that wasn't part of the plan for him originally! Will Max and Holly's brewing love conquer all in time for Christmas? Olivia Miles writes such great characters, cozy towns, and holiday cheer! Enjoy this one!!


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Tuesday, September 27, 2016
Women's media organizations team up for voter registration initiative
A slate of women's magazines, like Essense and Women's Health, along with sites like Jezebel, HuffPost Women and The Cut, have signed on. Collectively, the initiative is expected to reach 67 million women in the U.S.
InStyle's Laura Brown on the Presidential Debate
In Paris, many of those abroad for Fashion Week are setting middle-of-the-night alarms so they can watch the debate live — at 3 a.m. local time. "I need to feel like I'm part of this," said Laura Brown, InStyle's editor in chief.
The state of publisher referral traffic from LinkedIn
According to data from analytics firm Chartbeat, since January the amount of traffic to publishers referred from LinkedIn has grown from 0.15 percent to 0.25 percent. (Before the spike in January, it was closer to 0.011 percent of total referral traffic).
With "vimages," The Economist is using Facebook to make low-budget video versions of its stories
Economist readers seem to responding well to the format. The video adaption of the Norberg book review reached 3.3 million people, which Waddell owes in part to its reliance on few words and lots of statistics to tell the story.
Sports Illustrated Reveals Arnold Palmer Cover
As the publication sometimes does when warranted, it has revealed its next cover a little earlier than usual.
Bloomberg Names Head of Digital Strategy
"Kibi Anderson is tasked with identifying and closing new partnerships and strategic relationships that help to expand the reach and monetization of our digital products," wrote Scott Havens, Bloomberg Media's global head of digital.
Why Snapchat's Spectacles Can Succeed Where Google Glass Failed
Our hopes and dreams are about to be fulfilled by a $129 pair of video-recording Spectacles that its creator calls a "toy." But while they are going to be super-fun to play with, Snap Inc.'s Spectacles are a serious brand extension for the company that created ephemeral visual conversation.
CSO Imran Khan Explains Snapchat's Rebrand to Snap Inc.
"We rebranded our company to Snap Inc. because we are bigger than just one app," Khan said. "Snap Inc. is a camera company—we believe that reinventing the camera represents our greatest opportunity to improve the way people live and communicate."
Day in the Life: Twitter's head of content planning thinks 'feed first'
Stacy Minero heads Twitter's content planning and creative agency development team, where she works with brands and agencies to tailor content for Twitter.
Disney Is Working With an Adviser on Potential Twitter Bid
Disney, the owner of ABC and ESPN, could obtain a new online outlet for entertainment, sports and news. Jack Dorsey, chief executive officer of Twitter, is on the board of Disney.
Grazia Hommes Launches in France
Romain Duris fronts the cover of a first issue of Grazia Hommes that's slated to hit French newsstands on Wednesday, coinciding with day two of Paris Fashion Week.
Associate Member Spotlight: License League, Inc.
Five questions with Daniel J. Schaible, COO/Founder, License League, Inc.: License League is about creating a delivery channel to be able to monetize content at the article level in an aggregated format.
MPA–The Association of Magazine Media has released its 2016/17 Magazine Media Factbook today, the definitive source of magazine media research. Since 1985, MPA has been compiling and packaging the most compelling and comprehensive facts and figures around magazine media. Derived from third-party sources and MPA's own research and data collection, the new Factbook has nearly 100 pages of current and useful information. "Nothing informs a discussion better than solid data," said MPA's President and Chief Executive Officer Linda Thomas Brooks, "and the 2016/17 Magazine Media Factbook has plenty of conversation starters. The research continues to show that magazine media is the most trusted, inspiring and influential of all media, and several new studies provide even more proof of magazine media's unique ability to drive sales."
Nielsen Catalina Solutions (NCS), the leader in helping CPG marketers optimize return on advertising spend (ROAS) with in-store purchase data, presented the study, "Yes, Advertising Works. Now, What's My ROAS Across Media Platforms?" at the Advertising Research Foundation's Audience Measurement 2016 conference. The study generated benchmarks that allow marketers to compare the return they should expect from every dollar of their cross-media, digital video, display, linear TV and magazine advertising spending. In its analysis, NCS worked with The Advertising Research Foundation, CBS Corporation, Meredith Corporation, Sequent Partners and a prominent technology and display advertising company.
October 25, 2016
MPA Offices
November 30, 2016
Hearst Tower
December 01, 2016
Hearst Tower
February 08, 2017
Conrad New York
Contact Alison Heisler, firstname.lastname@example.com or 212-872-3740, for details and custom opportunities.
Corn and beans have long been related — in history, in the garden, and in the kitchen. As two of the "three sisters," as Native Americans call them, they coexist happily. Vining beans climb cornstalks, while big leaves of squash carpet the ground below. Modern gardeners tend to give each one its own bed, and most plant sweet corn instead of the flint and flour corns traditionally used in three sisters growing strategies. However, varieties of corn and beans have long been intertwined. It's a treat to have them together in the summertime, such as in these sweet corn and shell bean recipes.


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Once again the captains of the Beach Haven Charter Fishing Association are both looking offshore for tuna and billfish as well as seeking some nice fluke in the inshore ocean waters around various types of structure as those fish begin their migration into the ocean.
Captain Matt Curtis made a couple of trips recently offshore with "Get Reel Sportfishing" which each trip resulting in several bluefin tuna. On most of the trips the crew boated both their "over" and "under" bluefin. The largest tuna were right at the 100-pound mark. Captain Mark has also taken a few inshore trips for summer flounder and has found improved luck with his keeper to throwback ratio. He is finding more fish in the 20-25 inch range with the bite in the ocean showing some definite improvement from recent weeks.
Captain Ray Lopez along with his mate Max Goldman recently had three action packed charters on the "Miss Liane" looking for fluke and anything else they might find in the area. One trip resulted in a total of 58 fish including 49 fluke to go with the rest black sea bass. Another trip had anglers catching over 30 fluke to go with a mix of sea bass, bluefish, and even some weakfish. On all of the trips multiple keepers were netted.
The annual White Marlin Tournament sponsored by the Beach Haven Marlin and Tuna Club is going on right now and Captain Jimmy Zavacky is fishing it with an eager crew on the "Reel Determined" with his son serving as mate. He says he is targeting bigeye tuna but will take whatever might come after his spread of lures. Also hoping to take home prizes in the tournament is Captain Bill Kaiser on his boat, "Tuna Sue" which has done well on tuna in the past in this event.
Additional information on the Beach Haven Charter Fishing Association can be found at www.BHCFA.net.
About The Author: Jim Hutchinson Sr.
Company: Beach Haven Charter Fishing Association
Area Reporting: Beach Haven-bay and ocean
Bio: I am a writer who will assemble the weekly reports for the association and submit them.


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Fri 8th Dec at 7:00pm
The Blockheads
@ Islington Assembly Hall, London
This event has been and gone!
Catch the next one:
Check out the info below for future tour dates, and track them to receive alerts when they tour near you
Never miss another 'The Blockheads' show
This event takes place at Islington Assembly Hall, which has achieved Bronze Status for disabled access from Attitude Is Everything.
The Blockheads
Formed in 1977 to promote Ian Dury's album New Boots and Panties on the first Stiff Records tour of the UK. The Blockheads are fronted by Derek 'The Draw' Hussey, who was Ian's best friend and is now the band's vocalist and wordsmith. Chaz Jankel, Norman Watt-Roy, John Turnbull and Mick Gallagher still remain from the original band and the current line-up is augmented by John Roberts on drums and a rolling line up of saxophonists including Gilad Atzmon, Terry Edwards or Dave Lewis. These legendary Brit-Funkers will be playing all the old favourites and new material.
The Blockheads tour dates


text: So my AppleCare finally ended on my iBook. I took it in to see a Genius because the battery has been crapping out lately. While I'll be getting a new battery, the Genius suggested I could upgrade my HDD. My question to you all is have any of you upgraded your HDD without professional installation and how did that go about? Where would you recommend getting a pro installation at an affordable rate (specifically in the Orange County area)?? What about hard drive recommendations?


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Your Europe, Your Say (YEYS) 2018!
The European Economic and Social Committee (EESC) is inviting you to Brussels on 15-16 March 2018, to join a real-life debate under the theme "United in diversity: a younger future for European culture". In order to participate, you need to register your school via the online registration form before 24 November 2017.
After the registration has closed, one school from each of the 28 EU Member States will be picked at random, to take part in the simulation. The selected schools will then choose three students in their pre-final year of secondary education (16 -18 years old) to represent them, as well as an accompanying teacher. If you are one of these three lucky students you have to make sure you are able to express yourself in English. The EESC will cover your and your teacher's travel and accommodation expenses.
Here is how the last year's event looked like:
Brussels is ready to welcome you!
Find out more about #YEYS2018 here.
Published: Thu, 16/11/2017 - 14:00
Info for young people in the western balkans


text: SensL has introduced the PCMPlus, an intelligent photon-counting module that incorporates a solid-state CMOS-compatible photon-counting sensor with a microprocessor-based control board. Operating from 400 to 850 nm, the Peltier-cooled unit features a typical QE of 45% at 650 nm, a timing jitter of ≤150 ps FWHM, an internal operating voltage of <40 V and an integrated counter that eliminates the need for external counting electronics. All module parameters can be remotely configured by PC via a USB interface, enabling users to optimize the sensor performance for particular applications. It is available with up to 16 sensors as well as in stand-alone and fiber-pigtailed versions.


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Conversations with Caregivers: Keeping Loved Ones Busy
A Special Series for Dementia Caregivers
Caring for a loved one with dementia isn't always easy. Pheasant Ridge Memory Center is hosting a discussion series to bring family caregivers together around topics of interest to share their experiences and provide their tips and tricks for what works best for them.
Seating is limited. To RSVP, call 540-685-4900.


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Main Menu
Research Compliance, Education and Outreach Menu
When we talk about conducting research ethically and having ethics, what does "ethics" mean? In the simplest terms, ethics are the norms for conduct that distinguish between acceptable and unacceptable behavior. So, when we talk about conducting research ethically, we are talking about the normal conduct that is acceptable when conducting research.There are numerous resources that guide us in understanding these norms of conduct, including, The Belmont Report, Good Clinical Practice Guidelines and even the Federal regulations. This section provides resources on these norms for conduct that guide research with human participants.
The Belmont Report is a report created by the National Commission for the Protection of Human Subjects of Biomedical and Behavioral Research. The purpose is to protect participants in clinical trials and research studies. The Belmont Report highlights 3 principles imperative to conducting ethical research which are justice, beneficence and respect for persons.
Researchers should minimize risks to study participants by utilizing procedures that are consistent with sound study design. Studies should be designed to ensure the research will likely develop or contribute to generalizable knowledge. In addition, researchers should document in their IRB application and support materials how the potential risks of participation are reasonable in relation to anticipated benefit and that the expected results of the research justify proceeding.
The Belmont Report Educational Video – Office for Human Research Protections (OHRP)
Office for HumanResearch Protections Educational Videos including:
Research Use of Human Biological Specimens and Other Private Information
Reviewing and Reporting Unanticipated Problems and Adverse Events
General informed Consent Requirements
Institutional Review Board (IRB) Membership
Complex Issues with Research Involving Vulnerable Populations
IRB Records (Parts One and Two)
The Basics of Informed Consent
The Basics of Informed Consent for non-English Speaking Individuals
Human Subject Protection Training at UH (CRECProgram)
Protecting Human Subjects Training (HRSA)
Good Clinical Practice (GCP): GCP is an international quality standard that is provided by International Conference on Harmonisation (ICH). GCP Guidelines include standards on how clinical trials should be conducted, defines the roles and responsibilities of clinical trial sponsors, clinical research investigators, and monitors and includes protections for human research participants in clinical trials.
To harmonize the various international drug development regulations and guidelines.
To provide a unified standard to facilitate the mutual acceptance of clinical data by the mutual acceptance of clinical data by the regulatory authorities and remove redundancy/duplication in development and review process.
Good Clinical Practice is an international ethical and scientific quality standard for designing, conducting, recording, and reporting trials that involve the participation of human subjects. Public assurance that the rights, the rights, safety, and well-being of trial participants are protected is consistent with the Declaration of Helsinki andThe Belmont Report and results in credible data.
ICH – GCP Guidelines
Collaborative Institutional TrainingInitiative (CITI) GCP course (Note you must login to CITI to complete the course.)
Good Clinical Practice: A Question & Answer Reference Guide
Addresses the most frequently asked questions in clinical research. Provides FDA supported interpretation of regulations in answering the questions. Updated yearly.
CenterWatch's training guides are "must-read" resources for those interested in clinical research and for seasoned professionals seeking to better understand their roles and improve the management of their clinical trials operations in a safe and ethical manner.
Becoming a Successful Clinical Research Investigator Guide to Patient Recruitment and Retention
Protecting Study Volunteers in Research – 4th edition
The CRC's Guide to Coordinating Clinical Research
Go to http://store.centerwatch.com/c-29-training-guides.aspx to purchase your own copy or contact the UH Clinical Research Center to check out a copy.
Responsible Conduct of Research, A. Shamoo & D. Resnick, 2003 (Oxford: Oxford).
All research conducted at University Hospitals Health System, and its affiliates, is governed by Federal and state regulations pertaining to human research protections, as well as other guidance and local policies and procedures.
The UH IRB regulates human subject research under the following U.S. Code of Federal Regulations: 21 CFR Parts 50 and56, 45 CFR Part 46, Subpart A (The Common Rule) and 45 CFR 160 and 164 (HIPAA Privacy Rule). Regulations that govern investigational new drugs (INDs) are found in 21 CFR Part 312; biologics are found in 21 CFR Part 600 and devices are found in 21 CFR Part 812.
A Federalwide Assurance (FWA) is an institution or organization's assurance to the Federal government that human subject research conducted at that site is in compliance with Federal regulations pertaining to the protection of human subjects.
The UH IRB's FWA is FWA00003937.
The Assurance states that all research involving human subjects that is conducted by UH staff or by researchers who fall under the purview of UH, or on UH premises or under its sponsorship, whether supported by Federal funds or not, must be reviewed and approved by the UH Cleveland Medical Center IRB. This policy also applies to protocols sponsored by UH staff conducting research at other hospitals, institutions, or community groups. In order to approve human subject research in accordance with Federal regulations the UH IRB must determine that all of the following requirements are satisfied:
Any UH clinician or staff involved in conducting human subject research at UH must read and be familiar with the following institutional policies.
R-39 Clinical Investigation
Key Points
CP-7 – Investigational Drugs
Key Points
R-40 Research Misconduct
Key Points
For a complete list of UH Research policies see Research section of the policies on the UH intranet.
For a complete list of UH IRB Policies click here.
UH IRB Policies address the following areas:
IRB Administration
Investigator Issues
New Protocols
Protocol Issues
Consent Issues
Vulnerable Populations
Actions for Approved Protocols
Miscellaneous Topics
Click here for a complete list of effective and bResearch SOPs.
Standard Operating Procedures (SOPs) are uniformly written procedures, with detailed instructions to record routine operations, processes and practices followed within a business organization. In clinical research, SOPs help define the group's (e.g., unit, division, department, institution, etc.) standard practices and daily processes conducted to assure execution of research tasks in accordance with institutional, state and federal guidances.
SOPs should contain adequate detail to clearly guide research staff through a particular procedure and thereby establish uniformity in the everyday functions of the department. Each SOP should have a specific aim but be written in a general format that can be easily followed by a broad audience. By laying out defined processes, the primary function of an SOP is to specifically avert procedural deviations.
Distribution, education and training on new departmental SOPs should be consistent. It is important to document the date research staff have been appropriately trained and are deemed competent to perform new SOPs implemented by the department. Research staff should be monitored consistently and receive refresher training at regular intervals to ensure compliance.
Existing SOPs should be reviewed at regular intervals to reassess applicability of the policy. Annual review is recommended and review prior to sponsor interactions is encouraged.
The following list of the USFood and Drug Administration (FDA) Guidance documents represents the Agency's current thinking on good clinical practice (GCP) and the conduct of clinical trials. For a complete list of all available FDA Guidance documents click here.
The principal investigator is ultimately responsible for the conduct of the study and for assuring compliance with IRB policies and procedures and with local, state and Federal regulations pertaining to human subject protections.
Even though a principal investigator may delegate specific tasks to other members of the research team, he or she cannot delegate the responsibility for ensuring that those tasks are completed according to institutional and Federal regulations. The following is a list of responsibilities a principal investigator must be aware of.
The primary responsibility of the principal investigator is to acknowledge and accept the responsibility and ethical obligations for protecting the rights and welfare of human research participants in compliance with current Federal regulations and IRB requirements governing human subject research.
The principal investigator is the ultimate protector of the research participant's rights and safety. He or sheis obligated to:
Investigators have a responsibility to protect human subjects and ensure the integrity of the data from clinical investigations. The following resources provides detailed information on the investigator's responsibility to 1) supervise a clinical study in which some study tasks are delegated to employees or colleagues of the investigator and 2) to protect the rights, safety, and welfare of study participants.
Presentation Archive: InvestigatorResponsibilities in FDA Regulated Research (6/2012)
Principal Investigators andDelegation of Study-Related Tasks to Co-Investigators and Study Staff
The '1572' is a Federal form and is the statement of the investigator that he/she will abide by the Federal guidelines set forth in the Code of Federal Regulations for the use of drugs in an investigational setting.
Presentation Archive: About FormFDA 1572 Statement of Investigator (7/2009)
FDA Guidance: Frequently Asked Questions – Statement of Investigator
To help develop a cadre of well-trained investigators, FDA has launched a Clinical Investigator Training Course targeted at medical professionals (experts who sign FDA Form 1572 before participating in an investigation). The 3-day course includes lectures given by senior FDA experts and guest lecturers from industry and academia, providing FDA's perspectives on new safety concerns, adverse event monitoring, compliance with legal and ethical obligations of clinical research, and acceptable scientific and analytic standards in clinical study design and conduct.
The annual courses, held in November, cover topics ranging from basic concepts of clinical trial design and how to review clinical data for sources of bias and errors to what to look for in drugs being studied in a clinical trial. Click here for a link to view videos, slides and transcripts from past sessions.
FDA Clinical Investigator Course 2012
Access videos, slides and transcripts from the FDA's annual Clinical Investigator Course. Topics include:
The Clinical Trial Protocol
FDA and the Regulation of Clinical Trials
Understanding the Investigator Brochure – Non-Clinical and Phase 1 Studies
Early Clinical Studies Session
Putting It All Together – Application and Compliance Issues
Breakout Sessions for Drug/Device/Biologics
Safety of Clinical Trials and Special Populations
FDA Clinical Investigator Course 2011
Access videos, slides and transcripts from the FDA's annual Clinical Investigator Course. Topics include:
FDA Structure
Good Clinical Practice – Key Topics
Investigator Responsibilities – Parts 1 and 2
Informed Consent and Ethical Considerations
CMC (Chemistry, Manufacturing and Controls – Quality) and the Investigator Brochure (Drugs and Biologics)
Pharmacology/Toxicology in the Investigator Brochure
FDA Perspective on International Studies
The Design of Clinical Trials
Clinical Trial Endpoints
Issues in Clinical Trial Designs for Devices
The Analysis of Investigator Data, Sources of Bias and Error
Safety Considerations
How to prepare an IND/IDE application
An IND is required for a clinical study if it is intended to support a:
There are three IND types:
The IND application must contain information in three broad areas:
Investigators who are IND holders are responsible for (this is a list of general responsibilities, and shouldnot be considered all inclusive):
Investigational New Drug (IND) Application– Information from the FDA
Presentation Archive: How Do You Know When and IND is Required? (4/2012)
Presentation Archive: Maintaining your IND with the FDA: Keys for Success (7/2012)
UH Investigator Initiated Research Checklist – Good Clinical Practice (GCP) Guidance
An investigational device exemption (IDE) allows the investigational device to be used in a clinical study in orderto collect safety and effectiveness data to support a Premarket Approval (PMA) application or a Premarket Notification[510(k)] submission to the FDA.
Clinical evaluation of devices that have not been cleared for marketing requires:
Investigators who are IDE holders are responsible for (this is a list of general responsibilities, and shouldnot be considered all inclusive):
Investigational Device Exemptions – Information from the FDA
Presentation Archive: How Do You Know When an IDE is Required? (3/2012)
Presentation Archive: Maintaining Your IDE with the FDA: Key for Success (7/2012)
The online, electronic Facilitated Review Hub is a collaborative effort within the Cleveland Clinical and Translational Science Collaborative (CTSC) to provide a centralized review and approval process for human subject research involving two or more CTSC affiliated institutions and its participating medical research facilities. Investigators at Case Western Reserve School of Medicine (CWRU), Cincinnati Children's Hospital Medical Center (CCHMC), Cleveland Clinic (CC), Nationwide Children's Hospital (NCH),The MetroHealth System (MHS), The Ohio State University (OSU), University Hospitals Cleveland Medical Center (UHCMC), and University of Cincinnati (UC) are eligible to utilize the 'Hub'. Once a protocol is approved at one CTSC institutional review board (IRB of Record), it can be submitted to the Hub for a Facilitated review by the other participating institutions (Named IRBs).
Researchers can register to access the IRB hub at https://mhirb.metrohealth.org/irb
Click here for an easy to follow flow chart of what you need to do and what you should expect in preparing to begin your research study. The UH Clinical Research Center is here to assist throughout this entire process, please contact the IRB Administration Office at 216-844-1529 with any questions.
IRB Policy – Protocol Submission Guidelines
Clinical Investigation (FDA) : Any experiment that involves a test article and one or more human subjects. The terms research, clinical research, clinical study, study, and clinical investigation are deemed to be synonymous.
Human Subject (DHHS) : A living individual about whom an investigator (whether professional or student) conducting research obtains (1) data through intervention or interaction with the individual or (2) identifiable private information.
Human Subject (FDA) : An individual who is or becomes a participant in research either as a recipient of the test article or on whose specimen a test article is used or as a control. A subject may be a healthy individual or a patient.
Research (DHHS) : A systematic investigation, including research development, testing, and evaluation, designed to develop or contribute to generalizable knowledge.
Protected Health Information – PHI is individually identifiable health information, including demographic data that is collected from an individual, and:
(UH Policy R-3 – Uses and Disclosures of PHI for Research Purposes)
Subject Identifiers under HIPAA include: (1) Names (including the patient's name and names of other individuals connected to the patient); (2) Geographic subdivisions smaller than a state (zip-code, street address, etc); (3) All elements of a date (except year) including birth date, admission date, discharge date, date of death, and all ages over 89); (4) Telephone numbers; (5) Fax numbers; (6) E-mail address; (7) Social security number; (8) Medical record number; (9) Health plan beneficiary numbers; (10) Account numbers; (11) Certificate/license numbers; (12) Vehicle identifiers and serial numbers including license plates; (13) Device identifiers and serial numbers; (14) Web universal resource locators (URLs); (15) Internet protocol (IP) address numbers, (16) Biometric identifiers including fingerprints and voice prints; (17) Full face photographic (or comparable) images; (18) Any other unique identifying number, characteristic, or code unless otherwise permitted by the Privacy Rule for re-identification (UH Policy R-3 – Uses and Disclosures of PHI for Research Purposes)
Test Article (FDA): Any drug for human use, biological product for human use, medical device for human use, human food additive, color additive, electronic product, or any other article for human use.
Mission: To provide global leadership to promote integrity and excellence for the clinical research profession. The Association of Clinical Research Professionals (ACRP) is the primary resource for clinical research professionals in the pharmaceutical, biotechnology and medical device industries, and those in hospital, academic medical centers and physician office settings.
ACRP Certification is granted in recognition of verified work experience and successful performance on a multiple-choice exam. ACRP currently offers three Certification exams, one for Clinical Research Associates/CRAs (Monitor), one for Clinical Research Coordinators/CRCs (Site), and one for Physician Investigators/PIs (MD). The exams are based on the industry's largest validated job analysis to ensure the exams reflect the frequency and importance of what CRAs, CRCs, and PIs do in the clinical research process.
CRA, CRC and PI exams are offered in March and September every year. Exams will evaluate your expertise on topics and regulations specifically related to your ability to make decisions in specific scenarios. For more information on each of the exams and the deadlines for registration, visit the ACRP website at www.acrpnet.org.
Mission: Public Responsibility in Medicine and Research (PRIM&R) is dedicated to advancing the highest ethical standards in the conduct of research through education, membership services, professional certification, and public policy initiatives. Via a wide variety of conferences and courses, PRIM&R provides balanced, well-researched, and accurate information on the range of ethical and regulatory issues affecting research while also offering unparalleled access to certification, networking, and professional development resources. For more information visit the PRIM&R website at http://www.primr.org/ .
PRIM&R is the professional home for those whose responsibilities include the protection and welfare of human and animal subjects. PRIM&R strives to enhance the ethical and responsible conduct of research through the educational and professional development of its members. Members include professionals from around the world responsible for overseeing the use of human and animal research subjects, including administrators, government officials, and academic department chairs, as well as members of institutional review boards, human research protection programs, animal care and use committees, and institutional biosafety committees.
PRIM&R sponsors two certification initiatives; the Certification for IRB Professionals (CIP®), for individuals working with institutional review boards and human research protection programs, and the Certification for Professional IACUC Administrators (CPIA), for those working with animal care and use committees. These credentials strengthen each profession by providing established bodies of relevant knowledge and standards of practice, and by providing potential career advancement opportunities.
The Society of Clinical Research Associates, a professional membership organization, was developed to provide educational programs, certification, and a forum for research professionals to exchange information.
SoCRA established the Certification Program for Clinical Research Professionals (CCRPs) in order to create an internationally accepted level of knowledge, education, and experience by which clinical research professionals will be recognized by the medical research community.
A Clinical Research Professional may serve as a clinical investigator, sub-investigator, clinical researcher, research nurse, administrator, coordinator, data manager, project manager, IRB coordinator, Quality Assurance specialist, regulatory affairs specialist, research pharmacist, consultant, or educator in clinical trials management. The examination is based on those areas that are common to all Clinical Research Professionals; any member of the clinical research team is able to apply for this certification. Questions are formulated to be straight -forward and easily understood. For more information visit the SoCRA website at http://www.socra.org/.
Mission: To globally foster and strengthen research management, administration and knowledge transfer in research management and administration.
The Society of Research Administrators International maintains 12 certificate programs encompassing every aspect of Research Administration – Hospitals, Universities, Nonprofits and Commercial Institutions. SRA's certificate programs offer comprehensive training specific to today's educational needs of research administrators.
The curriculum for each program includes a required half-day or full-day workshop, and four (4) to eight (8) required sessions, which are held at various SRA meetings throughout the year.
Clinical Trials Research Administration 101
Clinical Trials Research Administration 201
Financial Management
Human Research Protections
Introduction to Research Administration and Management
National Institutes of Health Grants Fundamentals
Research Integrity
Research Law
The Practice of Research Administration and Management
For more information visit the SRA website at http://www.srainternational.org/
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It's not that simple anymore. Led by consumer-savvy Media Director-Team Leader Donna Campanella, who applied her consumer-goods background from Sony Electronics to a fledging medium known as direct-to-consumer advertising, Pfizer has been at the forefront of the industry when it comes to placing ads. "We like to look at it by saying, `Let's find the connectivity sweet spot,' " Ms. Campanella says. "Could that be the evening news? Sure. But it could also be a talk show. It could be cable. It could be on the Internet on WebMD. People are not one-dimensional."
Pfizer does its media buying through Aegis Group's Carat, New York, a long-term relationship that only strengthened in 2001 following a shoot-out for the business. Pfizer had long used Carat, but the marketer had just acquired Warner-Lambert Co., and with $700 million in billings now up for grabs, Warner-Lambert executives were pushing for its incumbent, WPP Group's MindShare. Carat prevailed.
"We're looking at going beyond the basic media buys," Ms. Campanella says. "There's a lot of information out there, and that means using the entire marketing mix."
Like radio. An ugly stepchild when compared with network TV, cable, magazines and even the Internet, radio emerged in Pfizer's plans when it came time to break a campaign for Relpax this year.
Having just awarded Relpax to Havas' Arnold Worldwide, New York, in January, Pfizer was looking to position the migraine headache medication alongside market leader Imitrex from GlaxoSmithKline. But it not only wanted to differentiate the brand but differentiate the advertising.
Research showed that the consumer Relpax was trying to reach was a working mother, a person juggling work and family who rarely sits down to watch TV. In fact, she's more apt to hear a spot on the car radio while shuttling her kids back and forth to school and soccer.
So Relpax became the first DTC drug Pfizer ever launched without TV advertising.
"Not many brands introduce on radio, but we recognized there was an opportunity there," Ms. Campanella says. "Nobody looks at radio because of the fair balance without the visual like you have in television or magazines. We were one of the first brands to step up because we understood who our target was. We found that connectivity sweet spot."
Pfizer spent $546,000 on Relpax in 2003, all of it in magazine ads. In the first six months of this year, the pharmaceutical company has supported the brand with more than $19 million in measured media: $15.2 million in magazines, $1.3 million in Sunday newspaper magazines and $2.6 million on radio, according to TNS Media Intelligence/CMR. And still not one cent on any kind of TV.
"Donna's very savvy," says one network executive. "There are times, and I'm sure some of those times are unintentional, but there are times when I see a lot of copycatting going on when other people see what Donna and Pfizer are doing."
Part of that is being able to work backward, so to speak. Pfizer's first goal in marketing communications is to spark a conversation between patient and doctor. "By talking about the condition, the consumer is going to the doctor and starting that dialogue, so we think unbranded is as effective as branded," Ms. Campanella says.


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Near Locust Grove in Orange County, Virginia — The American South (Mid-Atlantic)
Morning of May 6
The Confederates struck first. At 4:30 a.m., the Wilderness erupted with a deafening chorus of artillery and small arms. The Southerners closed with their blueclad opponents, only to feel the shock of Union volleys fired at point blank range. Ewell's men fell back to this line of trenches where they in turn repulsed Federal counterassaults. By mid-morning this area grew relatively quiet while the armies clashed in earnest a few miles south.
Location. 38° 19.402′ N, 77° 45.773′ W. Marker is near Locust Grove, Virginia, in Orange County. Marker can be reached from Constitution Highway (State Highway 20), on the right when traveling west. Touch for map. The marker is in Wilderness Battlefield at stop 5 of the Gordon Flank Attack trail, near Driving Tour Stop Two (the Exhibit Shelter).
Other nearby markers. At least 8 other markers are within walking distance of this marker. Fighting on the Evening of May 5, 1864 (about 500 feet away, measured in a direct line); Gordon's Attack Falters (about 700 feet away); John Gordon Proposes a Flank Attack (approx. 0.2 miles away); Gordon's Flank Attack (approx. 0.2 miles away); Wilderness Battlefield Memorial (approx. 0.2 miles away); The Federals Fall Back (approx. ¼ mile away); The Culpeper Mine Road (approx. ¼ mile away); The Confederate Defense (approx. half a mile away). Touch for a list and map of all markers in Locust Grove.
More about this marker. The upper half of the marker displays a battle map indicating positions of the forces engaged and the important roads.
Also see . . . Gordon Flank Attack Trail. National Park Service page detailing the Gordon Flank Attack Trail. (Submitted on April 27, 2008, by Craig Swain of Leesburg, Virginia.)
Categories. • War, US Civil •
Credits. This page was last revised on June 16, 2016. This page originally submitted on April 27, 2008, by Craig Swain of Leesburg, Virginia. This page has been viewed 827 times since then and 30 times this year. Photos: 1, 2, 3. submitted on April 27, 2008, by Craig Swain of Leesburg, Virginia.


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When Swiss telephone subscribers begin dialing direct to the Soviet Union on July 1 they should have no trouble remembering the code. Just dial 007. A spokesman for the Swiss postal administration announced the new service Monday and said any connectin to Ian Fleming's famous screen spy, James Bond, was unintentional.
"It's just one of those thigs -- 7 was the next number free," the spokesman said.
By adding three more digits to the basic code, it will be possible to dial numbers directly in five Russian cities -- Moscow, Minsk, Leningrad, Kiev, and Tallinn.


text: 36517 LUCAS Dr, Denham Springs, LA Posted on April 25, 2015 by buyorsellbatonrouge 0 Flares Filament.io 0 Flares × Denham Springs, LA Home for Sale ! View the Property Details, More Photos, Map & School information here at the updated Single Property Website! Live Oak schools and No flood zone! This 4 bedroom home is spacious and nicely configured with a split and open floor plan. The living and hall have new wood laminate flooring, tile in the kitchen, stainless steel appliances. The 4th bedroom could be a mother in law suite/office/playroom. There is a covered patio and large fenced in yard with swing set to remain. This allows for ample parking with the J-Swing garage and extra slot parking. Come see this beauty today before it's gone. Schedule a Showing Search All Homes For Sale Homes from $150,000-$300,000 in Livingston Parish 4 bedroom homes for sale in Denham Springs Baton Rouge Homes For Sale What is Your Home Worth? Homes Close to Where You Work Free List of Foreclosed Homes For Sale Avoid Foreclosure Call 225-921-7477 for more information on this or any other property. Visit Property Website Michelle CobbKeller Williams RealtyEmail Me Now225-921-7477Licensed In: LouisianaLicense #: 0000076780 36517 LUCAS DrDenham Springs, LA 70706Bedrooms:4Bathrooms: 2 fullList Price: $ 214,900Living Area Approx: 1815 Have questions? Ask me.


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May 7, 2010 -- Carestream Health of Rochester, NY, has completed orders for medical imaging and image information management systems for medical facilities serving the Muscogee (Creek) Nation and Citizen Potawatomi Nation in Oklahoma.
The Citizen Potawatomi Nation Health Service in Shawnee purchased a Carestream PACS network and a Carestream DRX-Evolution system to move from film- and paper-based workflow to an all-digital environment.
The Muscogee (Creek) Nation Division of Health ordered a DRX-Evolution and Carestream DryView 5800 laser imager. The DRX-Evolution will be installed in the Okmulgee Indian Health Center, one of four outpatient clinics serving the Muscogee Nation.
Carestream nets French accreditation, April 30, 2010
Carestream takes 7 Canadian orders, April 14, 2010
Carestream inks deal with OncoVision, April 13, 2010
Carestream scores DRX-1 orders, April 8, 2010
Carestream taking orders for mobile DR, March 24, 2010
Copyright © 2010 AuntMinnie.com


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You've probably heard or have seen the internet stories about how supposedly a McDonald's burger will not rot. The facts that we do know about McDonald's burgers is that when it is left out in the air it will not grow mold. Another thing we know is that in order for mold to grow, the following things need to be present: mold spores, air, moisture, and a hospitable climate. Many believe that the reason behind this non-decomposing phenomenon is because there are a lot of chemical preservatives inside the burger, making it an inhospitable environment for mold to grow.
Scientists have experimented with McDonald's burgers and have brought up multiple theories as to why these burgers simply will not rot. They have stated that one reason could be that these burgers have a high salt level and is preventing the decomposition. Others believe that the small size of a McDonald's burger is allowing it to dehydrate so fast enough that there is not enough moisture present for mold to grow in.
Of all the theories, one that seems to be quite possible. It states that the reason behind the burger not being able to grow mold would be because there are no mold spores present on a burger from McDonald's, or in the air in or around where the burgers may have been stored. Even after all of these theories, we do now know that McDonald's burger do indeed rot and decompose…under certain circumstances.
When asked about whether or not there was an explanation about all of this burger chaos, Dr. Keith Warriner, the program director at the University of Guelph's Department of Food Science and Quality Assurance, he responded by saying, "There have been a lot of online videos and photos touting the fact that when left out for an extended period of time, a McDonald's hamburger does not rot and that this is because they are laden with chemicals. The reality is that McDonald's hamburgers, french fries and chicken are like all foods, and do rot if kept under certain conditions. Essentially, the microbes that cause rotting are a lot like ourselves, in that they need water, nutrients, warmth and time to grow. If we take one or more of these elements away, then microbes cannot grow or spoil food."
Using a McDonald's burger as our prime example, we have found that the patty loses water in the form of steam when it is being cooked. The bun, of course, is made out of bread. So toasting it reduces the amount of moisture. This means that after the preparation, the hamburger is left pretty dry. But when left out in the open in a room, there is more water loss as the humidity in most buildings is around 40%. So, in the absence of moisture or high humidity, the hamburger simply dries out, rather than rot.
So there we have it. A McDonald's burger isn't exactly an "everlasting burger", it will decompose like all other foods. It just requires a longer process! Myth busted.


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Seven myths about learning from an American source - common sense to insightful New Zealand teachers?
Many people — educators included — still cling to some of these misconceptions about learning because they base what they think on their own experiences in school, ignoring what 21st century science and experience are revealing.
Here are seven of the biggest myths about learning that, unfortunately, guide the way that many schools are organized in this era of standardized test-based public school reform.
Basic Facts Come Before Deep Learning
This one translates roughly as, "Students must do the boring stuff before they can do the interesting stuff." Or, "Students must memorize before they can be allowed to think." In truth, students are most likely to achieve long-term mastery of basic facts in the context of engaging, student-directed learning.
Rigorous Education Means a Teacher Talking
Teachers have knowledge to impart, but durable learning is more likely when students talk, create, and integrate knowledge into meaningful projects. The art of a teacher is to construct ways for students to discover.
Covering It Means Teaching It
Teachers are often seduced by the idea that if they talk about a concept in class, they have taught it. At best, students get tentative ideas that will be quickly forgotten if not reinforced by a student-centered activity.
Teaching to Student Interests Means Dumbing It Down
If we could somehow see inside a student's brain, its circuitry would correspond to its knowledge. Since new learning always builds on what is already in the brain, teachers must relate classroom teaching to what students already know. Teachers who fail to do so, whether due to ignorance or in pursuit of a false idea of rigor, are running afoul of a biological reality.
Acceleration Means Rigor
Some schools accelerate strong students so that they can cover more material. Schools in the Innovative teachers are more likely to ask such students to delve deeper into important topics. Deep knowledge lays a stronger foundation for later learning.
A Quiet Classroom Means Good Learning
Students sitting quietly may simply be zoned out -- if not immediately, then within 15 minutes. A loud classroom, if properly controlled, includes the voices of many students who are actively engaged.
Traditional Schooling Prepares Students for Life
Listening to teachers and studying for tests has little to do with life in the world of work. People in the work world create, manage, evaluate, communicate, and collaborate


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Author: Akikaze Shirakumo
Artist: Akikaze Shirakumo
Genre: Ecchi, Harem, School Life, Seinen
Summary: The first year middle school Student Council Chairpersons (iincho) come from different elementary schools and different backgrounds. These six cute, glasses-wearing middle school girls often fight, but they have a common enemy in the sexual-harassing Student Council President. Will they be able to do their job without being distracted by infighting or thwarted by the controlling Student Council President?
– Chapter 1 – Release


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I do not enjoy intercourse with my husband. I researched on the internet and I found out that I need stimulation for a long time, 30 to 45 minutes. But my husband does not know that and he thinks that I am reaching climax. I have two questions: I let him think that I have reached climax so that I will not bother him and spoil his enjoyment. Is this regarded as lying? If he asks me whether I enjoyed it, I tell him yes, meaning that I only enjoyed seeing him. The more important question is that he stimulates me during intercourse but I do not reach a climax, then immediately after that I resort to masturbation until I reach a climax. Is this haraam? I know that masturbation is haraam but I know that my husband will never help me because it needs too much time, and he wants to fulfil his desire. What should I do?.
There is nothing wrong with what you have mentioned about pretending to have reached climax, rather it is indicative of the intelligence and wisdom with which Allaah has blessed you and of your good treatment of your husband. We ask Allaah to reward you for that and to make it a cause of happiness for you and your husband.
It is not lying if you tell him that you enjoyed it, meaning that you only enjoyed seeing him.
Masturbation is haraam, including the way that you have mentioned. What you have to do is to stop doing that, and repent from what has happened in the past. You should understand that this is may reduce your pleasure with your husband, and make the problem that you are suffering worse.
This problem is usually due to two main reasons:
1 – The husband's not understanding the problem or not having any interest in solving it after he finds out about it. From your question it seems that your husband is keen to make you enjoy it, and he understands that a woman may be deprived of that. Hence the way to deal with it is to be frank about it, in a way that will not hurt his feelings or spoil his enjoyment. Perhaps as time goes by you will find an opportunity to tell him, in an appropriate manner, so that you will not be forced to resort to something haraam and you will be able to enjoy that which Allaah has permitted for you.
2 – It may be due to the nature of the husband or wife, in terms of strength or weakness of desire. This can be dealt with by natural means, medication or psychological preparation and doing that which will increase love, and the most important is the wish of each spouse to fulfil the desire of the other.
See also question no. 23390.
And Allaah knows best.


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- klablo7
- 4 years ago
- Wedding: October 2014
Hi bees! I am thinking of getting a food truck at the end of the night. Do you think most guests would prefer comfort food (like grilled cheese, mac n cheese, etc) or desserts (crepes, waffles, ice cream)? We are doing cake and cookies for dessert. I think everyone would like a stop at the food truck on the way out (hopefully to the after party!) but just confused as to what to get! Thanks 🙂


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Dear List, I am desperately trying to get the german umlauts going for both vdr receiving EPG information (out of the air directly from the channels...) and via epg4vdr 0.5 http://www.wontorra.net/article.php?story=20050429181815661
I've noticed that standard EPG has the correct encoding, but only the one from epg4vdr has not. However the pulled .xml files still have the right (i.e. utf-8) encoding. Only when this information is transferred to vdr (I guess via SVDRP) umlauts and everything is distorted. Also then the dumped epgdata file contains wrongly encoded parts... Any ideas what I could do about this? Soeren _______________________________________________ vdr mailing list email@example.com http://www.linuxtv.org/cgi-bin/mailman/listinfo/vdr


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paragraphLike any major decision in life, moving home is full of rational and emotional thoughts and feelings. It's completely understandable. Moving involves spending a lot of money, making big decisions about the future and securing your family's happiness.
We believe there's a better way to move home. It's why we set-up Move Revolution and it's why we only employ decent, talented people to work hard to maximise your happiness and not our margins. The fact that our process costs, on average, half what a traditional estate agent will charge is both a great source of pride and proof our approach works.
paragraphPeople and principles.We set up Move Revolution in July 2009. There were just two of us; we had one small room but a host of big ideas. We set out to be the estate agent of choice where we operated. And we had a business plan that embraced the advantages of the Internet, did away with High Street shops and, crucially, recognised that better customer service was a key point of difference.
Our progress has been remarkable. Every customer who has let through us has bought into us and our unique way of working. Moreover, they've spread our message.
Personally, I think our real strength isn't in that business plan but in our people. And their dedication. We actually really care that buyers and tenants love their new home, and that the process leaves a lasting, positive impression.
Cliff Cooper - Founder & Director
Check out our available properties
You can see the properties we're currently marketing for rent by clicking the button below:View properties


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So as I sit here, still stuck on an energy rush from this weekends excitement and the one to come, it hit me.
How easily do things grab hold of us and jerk us into new directions. I'm generally a very focused worker. I've lately been a bit stand offish about my video game play, and been anti gadget.
Yet, here I am, tinkering endlessly with this modified nook, anticipating long hours of play with my friends this weekend, and unable to focus on my job. Albeit I'm doing my job, its with great determination that I remain on task.
How much more or less is our faith a part of our being when we are so easily pulled this way and that? That our hearts and minds are so easily redirected. I'm thankful to say that I've continued to read the word, remain in prayer, and give glory to God in what I'm doing and in what is being done for me… this time. This isn't always the case for me, or for others. To witness that these idols come and go, serves as an amazing contrast to Gods steadfast nature. Why would we need anything more? Why do we forget that? That answer is both simplistic and complex, sin, or that our chief idol is ourselves and not our Creator.


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Roger Keats, a former Illinois state senator and Cook County Board president, is packing up and leaving the Land of Lincoln for good. The 62-year-old Keats was a good government reformer who helped clean up the rampant corruption in the Chicago-area courts uncovered by Operations Greylord and Gambat.
But now he's throwing in the towel, and he and his wife are heading for Texas. "I am tired of subsidizing crooks," Keats told the Wilmette Beacon.
In "Good Bye and Good Luck," a letter to all the friends and political supporters he's leaving behind after 60 years, Keats says he is leaving what he calls "the most corrupt big city…and most corrupt state in America" with "a heavy heart."
"But enough is enough!" he writes. "The leaders of Illinois refuse to see we can't continue going in the direction we are and expect people who have options to stay here."
Indeed, Illinois has already lost a quarter of its population and will lose another seat in the next Congress.
And that's not the only sign of serious, and possibly irreversible, decline.
"Illinois just sold still more bonds and our credit rating is so bad we pay higher interest rates than junk bonds! Junk Bonds!" Keats points out.
"Illinois is ranked 50th for fiscal policy; 47th in job creation; first in unfunded pension liabilities; second largest budget deficit; first in failing schools; first in bonded indebtedness; highest sales tax in the nation; most judges indicted; and five of our last nine elected governors have been indicted. That is more than the other 49 states added together!...
"We are moving to Texas where there is no income tax while Illinois' just went up 67%. Texas' sales tax is half of ours, which is the highest in the nation. Southern states are supportive of job producers, taxpayers and folks who offer opportunities to their residents. Illinois shakes them down for every penny that can be extorted from them."
As a recent study by Americans for Tax Reform found, migration from high-tax states like Illinois to states with lower taxes and less government spending like Texas will dramatically alter the composition of future Congresses as more and more Americans, like the Keatses, vote with their feet.


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The 2011 LPGA Tour schedule will be released today, and Golfweek's Beth Ann Baldry says to expect a major twist.
The inaugural Founders Cup, designed in the spirit of pioneering LPGA founders, will be a charity-driven event in which players receive financial help for travel expenses, but don't take home a paycheck. Sources say the three-day tournament will be in Phoenix at the JW Marriott Desert Ridge on March 18-20, kicking off the tour's domestic schedule. The move fills a key market for the LPGA, which attracted record crowds at nearby Superstition Mountain when Safeway was sponsor of the former event.
Players still would receive official "money" and points toward rankings, the Hall of Fame and season-ending awards. They'd just give whatever money they earned back to charity.
It's an admirable idea, and I look forward to hearing more about it from Commissioner Mike Whan. (In-Kyung Kim may have inspired the idea after she donated all of her $220,000 check from the Lorena Ochoa Invitational to charity.) But some LPGA players may not be thrilled. It's relatively easy for established players with plenty of income to sign up, but it's a tougher assignment for those struggling to make a living on tour. Buy! Buy! Buy!If you have an extra $1.5 billion, you can jump into the bidding for Fortune Brands' golf division, which includes Titleist, Footjoy and Scotty Cameron putters.
Fortune Brands Inc., planning a breakup of the company, selected Morgan Stanley to run an auction for its golf division in a sale that may fetch as much as $1.5 billion, said four people with knowledge of the matter.
Morgan Stanley may approach potential strategic acquirers such as Nike Inc. and Adidas AG, as well as private-equity firms and Asian companies such as Sumitomo Rubber Industries Ltd., which owns the Srixon golf-ball brand, said the people, who asked not to be named because the discussions are private.
Fortune, also the maker of Jim Beam, announced Dec. 8 that it would split into three separate businesses and focus on distilled spirits, after activist investor William Ackman acquired a stake. The company will spin off its home and security division and sell or spin off the golf unit, which makes Titleist golf balls, Fortune said last month.
Sell! Sell! Sell!Japan may be home to one of the brightest stars in the game, Ryo Ishikawa, but the overall health of golf in Japan seems to be in shambles. I'm no Gordon Gekko, but when a company like Goldman Sachs stops investing in your business, it can't be good.
Goldman Sachs Group Inc. is selling its stake in Accordia Golf Co., ending an almost decade-long investment in the sport in Japan as player numbers fall.
A Goldman Sachs investment unit will sell 470,587 shares in Accordia, the Tokyo-based golf operator said in a statement today. The stake is worth about 37 billion yen ($445 million) based on today's closing price. Accordia's stock has lost 60 percent since Goldman Sachs took the company public in 2006.
Goldman Sachs spent more than 3 trillion yen since 1997 on assets in Japan, including golf facilities and office buildings. The nation's golf-course industry has been in decline since an asset bubble burst 20 years ago, and is unlikely to return to its former glory as the population shrinks and the economy stagnates, said Daisuke Seki of IB Research and Consulting Inc.
Divine DesignsGood news for architecture buffs: a large collection of Robert Trent Jones blueprints and other artifacts are being donated to Cornell University.
Donated by his sons, Rees and Robert Trent Jr., the collection covers seven decades of blueprints, correspondence, finanical records and photographs from Jones, who graduated from Cornell in 1930 and was 93 when he died in 2000 having designed 325 courses in more than 25 countries, including the layout at Cornell.
Tweet of the Day
@nikegolf: You never know who you'll see at the Nike Headquarters gym…@TigerWoods working out before his product mtgs http://plixi.com/p/68223193


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Up through version 8.15, versions of X-Plane were distributed via the network as simple downloads of compressed archives. Versions 8.16 and later use an installer program that fetches updated components as needed from network servers. Upgrade and installation techniques, needless to say, differ radically.
X-Plane media have also been sold through retail channels at various times.


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Our Physicians
- Linda F. Barr, M.D.
- Michael Baydarian, M.D.
- Ajay Behari, M.D.
- Jason M. Birnbaum, M.D.
- Brian J. Bohner, M.D.
- Philip Buescher, M.D.
- Jacques R. Conaway, M.D.
- Wendy Dubin, M.D.
- John H. Eppler, M.D.
- Mark S. Gosnell, M.D.
- Francois Gregoire, M.D.
- Daniel Grove, M.D.
- Preetam Jolepalem, M.D.
- Francis Khoo, M.D.
- Richard Linthicum, M.D.
- Anita Naik, D.O.
- Khalid Puthawala, M.D.
- George J. Pyrgos, M.D.
- Salim Rizk, M.D.
- Mitchell L. Schwartz, M.D.
- Hasan Shakoor, M.D.
- Daniel L. Shinners, M.D.
- Peter Sloane, M.D.
- Cynthia Soriano, M.D.
- Stuart R. Willes, M.D.
- Huimin Wu, M.D.
George J. Pyrgos, M.D.
Office Location:
Harry & Jeanette Weinberg Cancer Center
9103 Franklin Square Dr., Suite 300
Baltimore, MD 21237
Office Phone:
B.S. Marmara University Medical School, Istanbul, Turkey
M.D. University of Ioannina Medical School, Ioannina, Greece
Postgraduate Training:
Research Fellowship in Clinical Immunology, Johns Hopkins University
Residency in Internal Medicine, Johns Hopkins Bayview Medical Center
Fellowship in Pulmonary and Critical Care, Johns Hopkins University
Fellowship in Allergy Clinical Immunology, Johns Hopkins University
Board Certification:
American Board of Internal Medicine
American Board of Internal Medicine, Pulmonary Disease
Hospital Affiliations:
Franklin Square Hospital Center